Guide to the Human Genome
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Search of human proteins with 62388877

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|62388877 carboxypeptidase Z isoform 1 [Homo sapiens]
         (652 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|62388877 carboxypeptidase Z isoform 1 [Homo sapiens]              1371   0.0  
gi|62388875 carboxypeptidase Z isoform 2 precursor [Homo sapiens]    1338   0.0  
gi|62388879 carboxypeptidase Z isoform 3 [Homo sapiens]              1082   0.0  
gi|4503009 carboxypeptidase E preproprotein [Homo sapiens]            403   e-112
gi|9994201 carboxypeptidase X, member 1 precursor [Homo sapiens]      394   e-109
gi|4503011 carboxypeptidase N, polypeptide 1 precursor [Homo sap...   387   e-107
gi|223005864 carboxypeptidase X (M14 family), member 2 [Homo sap...   368   e-102
gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo...   342   6e-94
gi|22202611 carboxypeptidase D precursor [Homo sapiens]               320   3e-87
gi|53832021 carboxypeptidase M precursor [Homo sapiens]               266   3e-71
gi|38327526 carboxypeptidase M precursor [Homo sapiens]               266   3e-71
gi|6631081 carboxypeptidase M precursor [Homo sapiens]                266   3e-71
gi|4503827 frizzled 2 [Homo sapiens]                                   70   6e-12
gi|8393378 frizzled 3 [Homo sapiens]                                   68   2e-11
gi|4503833 frizzled 7 [Homo sapiens]                                   67   4e-11
gi|188528609 secreted frizzled-related protein 5 [Homo sapiens]        66   1e-10
gi|6005762 frizzled 10 [Homo sapiens]                                  65   2e-10
gi|27894385 frizzled 5 precursor [Homo sapiens]                        65   3e-10
gi|4503825 frizzled 1 [Homo sapiens]                                   64   3e-10
gi|34734079 frizzled 6 [Homo sapiens]                                  64   4e-10
gi|4503835 frizzled 9 [Homo sapiens]                                   64   4e-10
gi|56117838 secreted frizzled-related protein 1 [Homo sapiens]         64   6e-10
gi|29244926 corin [Homo sapiens]                                       64   6e-10
gi|38455388 frizzled-related protein [Homo sapiens]                    63   7e-10
gi|48475052 secreted frizzled-related protein 2 precursor [Homo ...    61   4e-09
gi|13994190 frizzled 8 [Homo sapiens]                                  61   4e-09
gi|13899255 membrane frizzled-related protein [Homo sapiens]           60   6e-09
gi|61743916 carboxypeptidase A4 preproprotein [Homo sapiens]           60   6e-09
gi|170784838 secreted frizzled-related  protein 4 [Homo sapiens]       56   9e-08
gi|22547161 frizzled 4 [Homo sapiens]                                  53   8e-07

>gi|62388877 carboxypeptidase Z isoform 1 [Homo sapiens]
          Length = 652

 Score = 1371 bits (3549), Expect = 0.0
 Identities = 652/652 (100%), Positives = 652/652 (100%)

Query: 1   MPPPPPLLLLTVLVVAAARPGCEFERNPAGECHRPPAADSATCVDLQLRTCSDAAYNHTT 60
           MPPPPPLLLLTVLVVAAARPGCEFERNPAGECHRPPAADSATCVDLQLRTCSDAAYNHTT
Sbjct: 1   MPPPPPLLLLTVLVVAAARPGCEFERNPAGECHRPPAADSATCVDLQLRTCSDAAYNHTT 60

Query: 61  FPNLLQHRSWEVVEASSEYILLSVLHQLLEGQCNPDLRLLGCAVLAPRCEGGWVRRPCRH 120
           FPNLLQHRSWEVVEASSEYILLSVLHQLLEGQCNPDLRLLGCAVLAPRCEGGWVRRPCRH
Sbjct: 61  FPNLLQHRSWEVVEASSEYILLSVLHQLLEGQCNPDLRLLGCAVLAPRCEGGWVRRPCRH 120

Query: 121 ICEGLREVCQPAFDAIDMAWPYFLDCHRYFTREDEGCYDPLEKLRGGLEADEALPSGLPP 180
           ICEGLREVCQPAFDAIDMAWPYFLDCHRYFTREDEGCYDPLEKLRGGLEADEALPSGLPP
Sbjct: 121 ICEGLREVCQPAFDAIDMAWPYFLDCHRYFTREDEGCYDPLEKLRGGLEADEALPSGLPP 180

Query: 181 TFIRFSHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPE 240
           TFIRFSHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPE
Sbjct: 181 TFIRFSHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPE 240

Query: 241 VKLIGNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAA 300
           VKLIGNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAA
Sbjct: 241 VKLIGNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAA 300

Query: 301 AEGAGYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLAETRGARSDHIPIPQHYWWGKVAPE 360
           AEGAGYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLAETRGARSDHIPIPQHYWWGKVAPE
Sbjct: 301 AEGAGYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLAETRGARSDHIPIPQHYWWGKVAPE 360

Query: 361 TKAIMKWMQTIPFVLSASLHGGDLVVSYPFDFSKHPQEEKMFSPTPDEKMFKLLSRAYAD 420
           TKAIMKWMQTIPFVLSASLHGGDLVVSYPFDFSKHPQEEKMFSPTPDEKMFKLLSRAYAD
Sbjct: 361 TKAIMKWMQTIPFVLSASLHGGDLVVSYPFDFSKHPQEEKMFSPTPDEKMFKLLSRAYAD 420

Query: 421 VHPMMMDRSENRCGGNFLKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVELGCVKFPP 480
           VHPMMMDRSENRCGGNFLKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVELGCVKFPP
Sbjct: 421 VHPMMMDRSENRCGGNFLKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVELGCVKFPP 480

Query: 481 EEALYTLWQHNKESLLNFVETVHRGIKGVVTDKFGKPVKNARISVKGIRHDITTAPDGDY 540
           EEALYTLWQHNKESLLNFVETVHRGIKGVVTDKFGKPVKNARISVKGIRHDITTAPDGDY
Sbjct: 481 EEALYTLWQHNKESLLNFVETVHRGIKGVVTDKFGKPVKNARISVKGIRHDITTAPDGDY 540

Query: 541 WRLLPPGIHIVIAQAPGYAKVIKKVIIPARMKRAGRVDFILQPLGMGPKNFIHGLRRTGP 600
           WRLLPPGIHIVIAQAPGYAKVIKKVIIPARMKRAGRVDFILQPLGMGPKNFIHGLRRTGP
Sbjct: 541 WRLLPPGIHIVIAQAPGYAKVIKKVIIPARMKRAGRVDFILQPLGMGPKNFIHGLRRTGP 600

Query: 601 HDPLGGASSLGEATEPDPLRARRQPSADGSKPWWWSYFTSLSTHRPRWLLKY 652
           HDPLGGASSLGEATEPDPLRARRQPSADGSKPWWWSYFTSLSTHRPRWLLKY
Sbjct: 601 HDPLGGASSLGEATEPDPLRARRQPSADGSKPWWWSYFTSLSTHRPRWLLKY 652


>gi|62388875 carboxypeptidase Z isoform 2 precursor [Homo sapiens]
          Length = 641

 Score = 1338 bits (3462), Expect = 0.0
 Identities = 641/652 (98%), Positives = 641/652 (98%), Gaps = 11/652 (1%)

Query: 1   MPPPPPLLLLTVLVVAAARPGCEFERNPAGECHRPPAADSATCVDLQLRTCSDAAYNHTT 60
           MPPPPPLLLLTVLVVAAARPGCEFERNPA           ATCVDLQLRTCSDAAYNHTT
Sbjct: 1   MPPPPPLLLLTVLVVAAARPGCEFERNPA-----------ATCVDLQLRTCSDAAYNHTT 49

Query: 61  FPNLLQHRSWEVVEASSEYILLSVLHQLLEGQCNPDLRLLGCAVLAPRCEGGWVRRPCRH 120
           FPNLLQHRSWEVVEASSEYILLSVLHQLLEGQCNPDLRLLGCAVLAPRCEGGWVRRPCRH
Sbjct: 50  FPNLLQHRSWEVVEASSEYILLSVLHQLLEGQCNPDLRLLGCAVLAPRCEGGWVRRPCRH 109

Query: 121 ICEGLREVCQPAFDAIDMAWPYFLDCHRYFTREDEGCYDPLEKLRGGLEADEALPSGLPP 180
           ICEGLREVCQPAFDAIDMAWPYFLDCHRYFTREDEGCYDPLEKLRGGLEADEALPSGLPP
Sbjct: 110 ICEGLREVCQPAFDAIDMAWPYFLDCHRYFTREDEGCYDPLEKLRGGLEADEALPSGLPP 169

Query: 181 TFIRFSHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPE 240
           TFIRFSHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPE
Sbjct: 170 TFIRFSHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPE 229

Query: 241 VKLIGNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAA 300
           VKLIGNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAA
Sbjct: 230 VKLIGNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAA 289

Query: 301 AEGAGYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLAETRGARSDHIPIPQHYWWGKVAPE 360
           AEGAGYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLAETRGARSDHIPIPQHYWWGKVAPE
Sbjct: 290 AEGAGYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLAETRGARSDHIPIPQHYWWGKVAPE 349

Query: 361 TKAIMKWMQTIPFVLSASLHGGDLVVSYPFDFSKHPQEEKMFSPTPDEKMFKLLSRAYAD 420
           TKAIMKWMQTIPFVLSASLHGGDLVVSYPFDFSKHPQEEKMFSPTPDEKMFKLLSRAYAD
Sbjct: 350 TKAIMKWMQTIPFVLSASLHGGDLVVSYPFDFSKHPQEEKMFSPTPDEKMFKLLSRAYAD 409

Query: 421 VHPMMMDRSENRCGGNFLKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVELGCVKFPP 480
           VHPMMMDRSENRCGGNFLKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVELGCVKFPP
Sbjct: 410 VHPMMMDRSENRCGGNFLKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVELGCVKFPP 469

Query: 481 EEALYTLWQHNKESLLNFVETVHRGIKGVVTDKFGKPVKNARISVKGIRHDITTAPDGDY 540
           EEALYTLWQHNKESLLNFVETVHRGIKGVVTDKFGKPVKNARISVKGIRHDITTAPDGDY
Sbjct: 470 EEALYTLWQHNKESLLNFVETVHRGIKGVVTDKFGKPVKNARISVKGIRHDITTAPDGDY 529

Query: 541 WRLLPPGIHIVIAQAPGYAKVIKKVIIPARMKRAGRVDFILQPLGMGPKNFIHGLRRTGP 600
           WRLLPPGIHIVIAQAPGYAKVIKKVIIPARMKRAGRVDFILQPLGMGPKNFIHGLRRTGP
Sbjct: 530 WRLLPPGIHIVIAQAPGYAKVIKKVIIPARMKRAGRVDFILQPLGMGPKNFIHGLRRTGP 589

Query: 601 HDPLGGASSLGEATEPDPLRARRQPSADGSKPWWWSYFTSLSTHRPRWLLKY 652
           HDPLGGASSLGEATEPDPLRARRQPSADGSKPWWWSYFTSLSTHRPRWLLKY
Sbjct: 590 HDPLGGASSLGEATEPDPLRARRQPSADGSKPWWWSYFTSLSTHRPRWLLKY 641


>gi|62388879 carboxypeptidase Z isoform 3 [Homo sapiens]
          Length = 515

 Score = 1082 bits (2797), Expect = 0.0
 Identities = 515/515 (100%), Positives = 515/515 (100%)

Query: 138 MAWPYFLDCHRYFTREDEGCYDPLEKLRGGLEADEALPSGLPPTFIRFSHHSYAQMVRVL 197
           MAWPYFLDCHRYFTREDEGCYDPLEKLRGGLEADEALPSGLPPTFIRFSHHSYAQMVRVL
Sbjct: 1   MAWPYFLDCHRYFTREDEGCYDPLEKLRGGLEADEALPSGLPPTFIRFSHHSYAQMVRVL 60

Query: 198 RRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPEVKLIGNIHGNEVAGREM 257
           RRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPEVKLIGNIHGNEVAGREM
Sbjct: 61  RRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPEVKLIGNIHGNEVAGREM 120

Query: 258 LIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGAGYNGWTSGRQNAQ 317
           LIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGAGYNGWTSGRQNAQ
Sbjct: 121 LIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGAGYNGWTSGRQNAQ 180

Query: 318 NLDLNRNFPDLTSEYYRLAETRGARSDHIPIPQHYWWGKVAPETKAIMKWMQTIPFVLSA 377
           NLDLNRNFPDLTSEYYRLAETRGARSDHIPIPQHYWWGKVAPETKAIMKWMQTIPFVLSA
Sbjct: 181 NLDLNRNFPDLTSEYYRLAETRGARSDHIPIPQHYWWGKVAPETKAIMKWMQTIPFVLSA 240

Query: 378 SLHGGDLVVSYPFDFSKHPQEEKMFSPTPDEKMFKLLSRAYADVHPMMMDRSENRCGGNF 437
           SLHGGDLVVSYPFDFSKHPQEEKMFSPTPDEKMFKLLSRAYADVHPMMMDRSENRCGGNF
Sbjct: 241 SLHGGDLVVSYPFDFSKHPQEEKMFSPTPDEKMFKLLSRAYADVHPMMMDRSENRCGGNF 300

Query: 438 LKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVELGCVKFPPEEALYTLWQHNKESLLN 497
           LKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVELGCVKFPPEEALYTLWQHNKESLLN
Sbjct: 301 LKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVELGCVKFPPEEALYTLWQHNKESLLN 360

Query: 498 FVETVHRGIKGVVTDKFGKPVKNARISVKGIRHDITTAPDGDYWRLLPPGIHIVIAQAPG 557
           FVETVHRGIKGVVTDKFGKPVKNARISVKGIRHDITTAPDGDYWRLLPPGIHIVIAQAPG
Sbjct: 361 FVETVHRGIKGVVTDKFGKPVKNARISVKGIRHDITTAPDGDYWRLLPPGIHIVIAQAPG 420

Query: 558 YAKVIKKVIIPARMKRAGRVDFILQPLGMGPKNFIHGLRRTGPHDPLGGASSLGEATEPD 617
           YAKVIKKVIIPARMKRAGRVDFILQPLGMGPKNFIHGLRRTGPHDPLGGASSLGEATEPD
Sbjct: 421 YAKVIKKVIIPARMKRAGRVDFILQPLGMGPKNFIHGLRRTGPHDPLGGASSLGEATEPD 480

Query: 618 PLRARRQPSADGSKPWWWSYFTSLSTHRPRWLLKY 652
           PLRARRQPSADGSKPWWWSYFTSLSTHRPRWLLKY
Sbjct: 481 PLRARRQPSADGSKPWWWSYFTSLSTHRPRWLLKY 515


>gi|4503009 carboxypeptidase E preproprotein [Homo sapiens]
          Length = 476

 Score =  403 bits (1036), Expect = e-112
 Identities = 205/409 (50%), Positives = 271/409 (66%), Gaps = 16/409 (3%)

Query: 183 IRFSHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPEVK 242
           I F +H Y ++   L     +C  ++R Y++GRSF+GRELLVIE S  PG HE  EPE K
Sbjct: 49  ISFEYHRYPELREALVSVWLQCTAISRIYTVGRSFEGRELLVIELSDNPGVHEPGEPEFK 108

Query: 243 LIGNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAE 302
            IGN+HGNE  GRE+LI+LAQYLC+EY  GN  I  L+++TRIH++PS+NPDG+E AA++
Sbjct: 109 YIGNMHGNEAVGRELLIFLAQYLCNEYQKGNETIVNLIHSTRIHIMPSLNPDGFEKAASQ 168

Query: 303 GAGYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLAETRGARSDHI------PIPQHYWWGK 356
                 W  GR NAQ +DLNRNFPDL    Y + E  G  ++H+       + Q+    K
Sbjct: 169 PGELKDWFVGRSNAQGIDLNRNFPDLDRIVY-VNEKEGGPNNHLLKNMKKIVDQN---TK 224

Query: 357 VAPETKAIMKWMQTIPFVLSASLHGGDLVVSYPFDFSKHPQEEKMFSPTPDEKMFKLLSR 416
           +APETKA++ W+  IPFVLSA+LHGGDLV +YP+D ++     + +S +PD+ +F+ L+R
Sbjct: 225 LAPETKAVIHWIMDIPFVLSANLHGGDLVANYPYDETRSGSAHE-YSSSPDDAIFQSLAR 283

Query: 417 AYADVHPMMMDRSENRCGGNFLKRGSI---INGADWYSFTGGMSDFNYLHTNCFEITVEL 473
           AY+  +P M D +   C  N      +    NG  WYS  GGM DFNYL +NCFEITVEL
Sbjct: 284 AYSSFNPAMSDPNRPPCRKNDDDSSFVDGTTNGGAWYSVPGGMQDFNYLSSNCFEITVEL 343

Query: 474 GCVKFPPEEALYTLWQHNKESLLNFVETVHRGIKGVVTDKFGKPVKNARISVKGIRHDIT 533
            C KFPPEE L T W+ NK SL++++E +HRG+KG V D  G P+ NA ISV+GI HD+T
Sbjct: 344 SCEKFPPEETLKTYWEDNKNSLISYLEQIHRGVKGFVRDLQGNPIANATISVEGIDHDVT 403

Query: 534 TAPDGDYWRLLPPGIHIVIAQAPGYAKVIKKVIIPARMKRAGRVDFILQ 582
           +A DGDYWRLL PG + + A APGY  + KKV +P     A  VDF L+
Sbjct: 404 SAKDGDYWRLLIPGNYKLTASAPGYLAITKKVAVP--YSPAAGVDFELE 450


>gi|9994201 carboxypeptidase X, member 1 precursor [Homo sapiens]
          Length = 734

 Score =  394 bits (1011), Expect = e-109
 Identities = 194/388 (50%), Positives = 264/388 (68%), Gaps = 10/388 (2%)

Query: 185 FSHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPEVKLI 244
           F HH+Y  M +++++   +C ++ R YSIG+S+ G +L V+E S +PG+HEL EPEV+ +
Sbjct: 297 FQHHNYKAMRKLMKQVQEQCPNITRIYSIGKSYQGLKLYVMEMSDKPGEHELGEPEVRYV 356

Query: 245 GNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGA 304
             +HGNE  GRE+L+ L Q+LC E+L GNPR+ RLL+  RIHLLPSMNPDGYE+A   G+
Sbjct: 357 AGMHGNEALGRELLLLLMQFLCHEFLRGNPRVTRLLSEMRIHLLPSMNPDGYEIAYHRGS 416

Query: 305 GYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLAETRG-----ARSDHIPIPQHYWW--GKV 357
              GW  GR N Q++DLN NF DL +  +  A+  G       + H+P+P +Y      V
Sbjct: 417 ELVGWAEGRWNNQSIDLNHNFADLNTPLWE-AQDDGKVPHIVPNHHLPLPTYYTLPNATV 475

Query: 358 APETKAIMKWMQTIPFVLSASLHGGDLVVSYPFDFSKHPQEEKMFSPTPDEKMFKLLSRA 417
           APET+A++KWM+ IPFVLSA+LHGG+LVVSYPFD ++ P   +  +PTPD+ +F+ LS  
Sbjct: 476 APETRAVIKWMKRIPFVLSANLHGGELVVSYPFDMTRTPWAARELTPTPDDAVFRWLSTV 535

Query: 418 YADVHPMMMDRSENRC-GGNFLKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVELGCV 476
           YA  +  M D S   C   +F   G+IINGADW++  G M+DF+YLHTNCFE+TVEL C 
Sbjct: 536 YAGSNLAMQDTSRRPCHSQDFSVHGNIINGADWHTVPGSMNDFSYLHTNCFEVTVELSCD 595

Query: 477 KFPPEEALYTLWQHNKESLLNFVETVHRGIKGVVTDKFGK-PVKNARISVKGIRHDITTA 535
           KFP E  L   W++NK++LL ++E V  GI GVV DK  +  + +A I+V GI HD+TTA
Sbjct: 596 KFPHENELPQEWENNKDALLTYLEQVRMGIAGVVRDKDTELGIADAVIAVDGINHDVTTA 655

Query: 536 PDGDYWRLLPPGIHIVIAQAPGYAKVIK 563
             GDYWRLL PG ++V A A GY  V +
Sbjct: 656 WGGDYWRLLTPGDYMVTASAEGYHSVTR 683


>gi|4503011 carboxypeptidase N, polypeptide 1 precursor [Homo
           sapiens]
          Length = 458

 Score =  387 bits (993), Expect = e-107
 Identities = 193/380 (50%), Positives = 253/380 (66%), Gaps = 10/380 (2%)

Query: 183 IRFSHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPEVK 242
           + F HH Y  +VR L +  + C  + R YSIGRS +GR L V+EFS  PG HE +EPEVK
Sbjct: 21  VTFRHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHLYVLEFSDHPGIHEPLEPEVK 80

Query: 243 LIGNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAE 302
            +GN+HGNE  GRE+++ L+++LC E+   N RI +L+  TRIH+LPSMNPDGYEVAAA+
Sbjct: 81  YVGNMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPSMNPDGYEVAAAQ 140

Query: 303 GAGYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLAETRGARSDHIPIPQHYWWGKVAPETK 362
           G    G+  GR NA  +DLNRNFPDL + Y    E  G  + H+P+P + W  +V PET+
Sbjct: 141 GPNKPGYLVGRNNANGVDLNRNFPDLNT-YIYYNEKYGGPNHHLPLPDN-WKSQVEPETR 198

Query: 363 AIMKWMQTIPFVLSASLHGGDLVVSYPFDFSKHPQ----EEKMFSPTPDEKMFKLLSRAY 418
           A+++WM +  FVLSA+LHGG +V +YP+D S   +         +PTPD+K+F+ L++ Y
Sbjct: 199 AVIRWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRTASTPTPDDKLFQKLAKVY 258

Query: 419 ADVHPMMMDRSENRCGGNFLKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVELGCVKF 478
           +  H  M       CG  F     I NGA WYS + GM DFNYLHTNCFEIT+EL C KF
Sbjct: 259 SYAHGWMFQGW--NCGDYF--PDGITNGASWYSLSKGMQDFNYLHTNCFEITLELSCDKF 314

Query: 479 PPEEALYTLWQHNKESLLNFVETVHRGIKGVVTDKFGKPVKNARISVKGIRHDITTAPDG 538
           PPEE L   W  N+E+L+ F+E VH+GIKG+V D+    + NA ISV GI HD+T+   G
Sbjct: 315 PPEEELQREWLGNREALIQFLEQVHQGIKGMVLDENYNNLANAVISVSGINHDVTSGDHG 374

Query: 539 DYWRLLPPGIHIVIAQAPGY 558
           DY+RLL PGI+ V A APGY
Sbjct: 375 DYFRLLLPGIYTVSATAPGY 394


>gi|223005864 carboxypeptidase X (M14 family), member 2 [Homo
           sapiens]
          Length = 756

 Score =  368 bits (945), Expect = e-102
 Identities = 185/414 (44%), Positives = 260/414 (62%), Gaps = 18/414 (4%)

Query: 185 FSHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPEVKLI 244
           F HH+Y +M ++++     C ++ R Y+IG+S  G +L  +E S  PG+HE+ EPE   I
Sbjct: 316 FKHHNYKEMRQLMKVVNEMCPNITRIYNIGKSHQGLKLYAVEISDHPGEHEVGEPEFHYI 375

Query: 245 GNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGA 304
              HGNEV GRE+L+ L Q++C EYL  N RI  L+  TRIH+LPS+NPDGYE A   G+
Sbjct: 376 AGAHGNEVLGRELLLLLVQFVCQEYLARNARIVHLVEETRIHVLPSLNPDGYEKAYEGGS 435

Query: 305 GYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLAETRGARSDHIP--IPQHY-----WW--- 354
              GW+ GR     +D+N NFPDL +  +  AE R     ++P  +P HY     W+   
Sbjct: 436 ELGGWSLGRWTHDGIDINNNFPDLNTLLWE-AEDR----QNVPRKVPNHYIAIPEWFLSE 490

Query: 355 -GKVAPETKAIMKWMQTIPFVLSASLHGGDLVVSYPFDFSKHPQEEKMFSPTPDEKMFKL 413
              VA ET+A++ WM+ IPFVL  +L GG+LVV+YP+D  + P + +  +PTPD+ +F+ 
Sbjct: 491 NATVAAETRAVIAWMEKIPFVLGGNLQGGELVVAYPYDLVRSPWKTQEHTPTPDDHVFRW 550

Query: 414 LSRAYADVHPMMMDRSENRCGG-NFLKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVE 472
           L+ +YA  H +M D     C   +F K    +NGA W++  G ++DF+YLHTNCFE+++ 
Sbjct: 551 LAYSYASTHRLMTDARRRVCHTEDFQKEEGTVNGASWHTVAGSLNDFSYLHTNCFELSIY 610

Query: 473 LGCVKFPPEEALYTLWQHNKESLLNFVETVHRGIKGVVTDKFGKPVKNARISVKGIRHDI 532
           +GC K+P E  L   W++N+ESL+ F+E VHRGIKG+V D  GK + NA ISV+GI HDI
Sbjct: 611 VGCDKYPHESQLPEEWENNRESLIVFMEQVHRGIKGLVRDSHGKGIPNAIISVEGINHDI 670

Query: 533 TTAPDGDYWRLLPPGIHIVIAQAPGYAKVIKKVIIPARMKRAGRVDFILQPLGM 586
            TA DGDYWRLL PG ++V A+A G+    K  ++   M  A R DF L    M
Sbjct: 671 RTANDGDYWRLLNPGEYVVTAKAEGFTASTKNCMVGYDM-GATRCDFTLSKTNM 723


>gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo
           sapiens]
          Length = 1158

 Score =  342 bits (877), Expect = 6e-94
 Identities = 175/404 (43%), Positives = 243/404 (60%), Gaps = 25/404 (6%)

Query: 185 FSHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPEVKLI 244
           F HHSY  M ++++     C  + RTYS+G+S  G ++  +E S  PG+HEL EPE +  
Sbjct: 562 FRHHSYKDMRQLMKVVNEECPTITRTYSLGKSSRGLKIYAMEISDNPGEHELGEPEFRYT 621

Query: 245 GNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGA 304
             IHGNEV GRE+L+ L QYLC EY  GNPR++ L+  TRIHL+PS+NPDGYEVAA  G+
Sbjct: 622 AGIHGNEVLGRELLLLLMQYLCREYRDGNPRVRSLVQDTRIHLVPSLNPDGYEVAAQMGS 681

Query: 305 GYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLAETR----GARSDHIPIPQHYWW--GKVA 358
            +  W  G    +  D+  +FPDL S  +   E +       ++++PIP+ Y      V+
Sbjct: 682 EFGNWALGLWTEEGFDIFEDFPDLNSVLWGAEERKWVPYRVPNNNLPIPERYLSPDATVS 741

Query: 359 PETKAIMKWMQTIPFVLSASLHGGDLVVSYPFDFSKHPQEEKMFS--------------- 403
            E +AI+ WM+  PFVL A+L+GG+ +VSYP+D ++ P +E++ +               
Sbjct: 742 TEVRAIIAWMEKNPFVLGANLNGGERLVSYPYDMARTPTQEQLLAAAMAAARGEDEDEVS 801

Query: 404 ---PTPDEKMFKLLSRAYADVHPMMMDRSENRCGGNFLKRG-SIINGADWYSFTGGMSDF 459
               TPD  +F+ L+ ++A  H  + +     C       G  I+NGA W   TG ++DF
Sbjct: 802 EAQETPDHAIFRWLAISFASAHLTLTEPYRGGCQAQDYTGGMGIVNGAKWNPRTGTINDF 861

Query: 460 NYLHTNCFEITVELGCVKFPPEEALYTLWQHNKESLLNFVETVHRGIKGVVTDKFGKPVK 519
           +YLHTNC E++  LGC KFP E  L   W++NKE+LL F+E VHRGIKGVVTD+ G P+ 
Sbjct: 862 SYLHTNCLELSFYLGCDKFPHESELPREWENNKEALLTFMEQVHRGIKGVVTDEQGIPIA 921

Query: 520 NARISVKGIRHDITTAPDGDYWRLLPPGIHIVIAQAPGYAKVIK 563
           NA ISV GI H + TA  GDYWR+L PG + V A A GY    K
Sbjct: 922 NATISVSGINHGVKTASGGDYWRILNPGEYRVTAHAEGYTPSAK 965


>gi|22202611 carboxypeptidase D precursor [Homo sapiens]
          Length = 1380

 Score =  320 bits (820), Expect = 3e-87
 Identities = 175/400 (43%), Positives = 243/400 (60%), Gaps = 33/400 (8%)

Query: 185 FSHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPEVKLI 244
           F HH +  M   LRR A+   ++ R YS+G+S + REL V+E S  PG HE  EPE K I
Sbjct: 501 FHHHHFPDMEIFLRRFANEYPNITRLYSLGKSVESRELYVMEISDNPGVHEPGEPEFKYI 560

Query: 245 GNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGA 304
           GN+HGNEV GRE+L+ L +YLC  +   +P +  L++ TRIHL+PSMNPDGYE  + EG 
Sbjct: 561 GNMHGNEVVGRELLLNLIEYLCKNFGT-DPEVTDLVHNTRIHLMPSMNPDGYE-KSQEGD 618

Query: 305 GYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLAETRGARSDHIPIPQHYWWGKVAPETKAI 364
             +    GR N+ N DLNRNFPD   ++ ++ +                     PET A+
Sbjct: 619 SIS--VIGRNNSNNFDLNRNFPD---QFVQITDP------------------TQPETIAV 655

Query: 365 MKWMQTIPFVLSASLHGGDLVVSYPFDFSKHPQEEKMFSPTPDEKMFKLLSRAYADVHPM 424
           M WM++ PFVLSA+LHGG LVV+YPFD  +  Q    +S +PD+ +F+ ++ +Y+  +  
Sbjct: 656 MSWMKSYPFVLSANLHGGSLVVNYPFDDDE--QGLATYSKSPDDAVFQQIALSYSKENSQ 713

Query: 425 MMDRS--ENRCGGNFLKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVELGCVKFPPEE 482
           M      +N     +   G I NGA WY+  GGM D+NYL TNCFE+T+ELGCVK+P E+
Sbjct: 714 MFQGRPCKNMYPNEYFPHG-ITNGASWYNVPGGMQDWNYLQTNCFEVTIELGCVKYPLEK 772

Query: 483 ALYTLWQHNKESLLNFVETVHRGIKGVVTDKF-GKPVKNARISVKGIRHDITTAPDGDYW 541
            L   W+ N+ SL+ F++ VH+G++G V D   G+ + NA ISV  I H +TT   GDYW
Sbjct: 773 ELPNFWEQNRRSLIQFMKQVHQGVRGFVLDATDGRGILNATISVAEINHPVTTYKTGDYW 832

Query: 542 RLLPPGIHIVIAQAPGYAKVIKKVIIPARMKRAGRVDFIL 581
           RLL PG + + A A GY  V K V +  + + A +V+F L
Sbjct: 833 RLLVPGTYKITASARGYNPVTKNVTV--KSEGAIQVNFTL 870



 Score =  280 bits (717), Expect = 2e-75
 Identities = 170/431 (39%), Positives = 241/431 (55%), Gaps = 53/431 (12%)

Query: 182 FIRFSHHSYAQMVRVLRRTASR-CAHVARTYSIGRSFDGRELLVIEFSSRPGQ------- 233
           F R+ H    ++   LR  A+     +AR +SIGRS +GR L V+  ++  G        
Sbjct: 55  FDRYYHEE--ELESALREAAAAGLPGLARLFSIGRSVEGRPLWVLRLTAGLGSLIPEGDA 112

Query: 234 ----------HELM--EPEVKLIGNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLN 281
                       L+   P+VKL+GN+HG+E   R++LIYLA+ L + Y  G+PR+ RLLN
Sbjct: 113 GPDAAGPDAAGPLLPGRPQVKLVGNMHGDETVSRQVLIYLARELAAGYRRGDPRLVRLLN 172

Query: 282 TTRIHLLPSMNPDGYEVAAAEGAGYN----GWTSGRQNAQNLDLNRNFPDL--TSEYYRL 335
           TT ++LLPS+NPDG+E A     G+        SGR N++  DLNR+FPD   T E   L
Sbjct: 173 TTDVYLLPSLNPDGFERAREGDCGFGDGGPSGASGRDNSRGRDLNRSFPDQFSTGEPPAL 232

Query: 336 AETRGARSDHIPIPQHYWWGKVAPETKAIMKWMQTIPFVLSASLHGGDLVVSYPFDFSKH 395
            E                     PE +A+++W++   FVLS +LHGG +V SYPFD S  
Sbjct: 233 DEV--------------------PEVRALIEWIRRNKFVLSGNLHGGSVVASYPFDDSPE 272

Query: 396 PQEEKMFSPTPDEKMFKLLSRAYADVHPMMMDRSENRCGGNFLK--RGSIINGADWYSFT 453
            +   ++S T D+++FK L++AYA  HP+M    E  C G+  +  +  I NGA WY   
Sbjct: 273 HKATGIYSKTSDDEVFKYLAKAYASNHPIMKT-GEPHCPGDEDETFKDGITNGAHWYDVE 331

Query: 454 GGMSDFNYLHTNCFEITVELGCVKFPPEEALYTLWQHNKESLLNFVETVHRGIKGVVTDK 513
           GGM D+NY+  NCFEIT+EL C K+PP   L   W++N+ESL+  +E VH G+KG V D 
Sbjct: 332 GGMQDYNYVWANCFEITLELSCCKYPPASQLRQEWENNRESLITLIEKVHIGVKGFVKDS 391

Query: 514 F-GKPVKNARISVKGIRHDITTAPDGDYWRLLPPGIHIVIAQAPGYAKVIKKVIIPARMK 572
             G  ++NA ISV GI H+ITT   GD++RLL PG + +     GY  +    ++  +  
Sbjct: 392 ITGSGLENATISVAGINHNITTGRFGDFYRLLVPGTYNLTVVLTGYMPLTVTNVV-VKEG 450

Query: 573 RAGRVDFILQP 583
            A  VDF L+P
Sbjct: 451 PATEVDFSLRP 461



 Score =  197 bits (502), Expect = 2e-50
 Identities = 135/423 (31%), Positives = 209/423 (49%), Gaps = 57/423 (13%)

Query: 159  DPLEKLRGGLEADEALPSGLPPTFIRFS---------HHSYAQMVRVLRRTASRCAHVAR 209
            DP  K    L  D +  +GL    +R S         +HSY  +   LR       H+  
Sbjct: 896  DPTTKEFETLIKDLSAENGLESLMLRSSSNLALALYRYHSYKDLSEFLRGLVMNYPHITN 955

Query: 210  TYSIGRSFDGRELLVIEFSSRPGQHELMEPEVKLIGNIHGNEVAGREMLIYLAQYLCSEY 269
              ++G+S + R +  +E S++P   E  EP+++ +  IHGN   G E+L+ LA++LC  Y
Sbjct: 956  LTNLGQSTEYRHIWSLEISNKPNVSEPEEPKIRFVAGIHGNAPVGTELLLALAEFLCLNY 1015

Query: 270  LLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGAGYNGWTSGRQNAQNLDLNRNFPDLT 329
               NP + +L++ TRI ++PS+NPDG E A  +         G+ NA+  DL+ +F +  
Sbjct: 1016 KK-NPAVTQLVDRTRIVIVPSLNPDGRERAQEKDCTSK---IGQTNARGKDLDTDFTNNA 1071

Query: 330  SEYYRLAETRGARSDHIPIPQHYWWGKVAPETKAIMK-WMQTIPFVLSASLHGGDLVVSY 388
            S+                           PETKAI++  +Q   F LS +L GG ++V+Y
Sbjct: 1072 SQ---------------------------PETKAIIENLIQKQDFSLSVALDGGSMLVTY 1104

Query: 389  PFDFSKHPQEEKMFSPTPDEKMFKLLSRAYADVHPMM---MDRSENRCGGNFLKRGSIIN 445
            P+D        K      +++  K L+  YA+ HP M        N+   N    G ++ 
Sbjct: 1105 PYD--------KPVQTVENKETLKHLASLYANNHPSMHMGQPSCPNKSDENI--PGGVMR 1154

Query: 446  GADWYSFTGGMSDFNYLHTNCFEITVELGCVKFPPEEALYTLWQHNKESLLNFVETVHRG 505
            GA+W+S  G M D++  + +C EITV   C  FP    L +LW  NK SLL+ +  VH+G
Sbjct: 1155 GAEWHSHLGSMKDYSVTYGHCPEITVYTSCCYFPSAARLPSLWADNKRSLLSMLVEVHKG 1214

Query: 506  IKGVVTDKFGKPVKNARISV-KGIRHDITTAPDGDYWRLLPPGIHIVIAQAPGYAKVIKK 564
            + G V DK GKP+  A I + +GI+  + T   G +  LL PG+H +IA A GY +   +
Sbjct: 1215 VHGFVKDKTGKPISKAVIVLNEGIK--VQTKEGGYFHVLLAPGVHNIIAIADGYQQQHSQ 1272

Query: 565  VII 567
            V +
Sbjct: 1273 VFV 1275


>gi|53832021 carboxypeptidase M precursor [Homo sapiens]
          Length = 443

 Score =  266 bits (681), Expect = 3e-71
 Identities = 153/389 (39%), Positives = 212/389 (54%), Gaps = 30/389 (7%)

Query: 185 FSHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPEVKLI 244
           F++H    M   L+  A   + V   +SIG+S  GR L V+     P +H +  PE K +
Sbjct: 20  FNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYV 79

Query: 245 GNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGA 304
            N+HG+E  GRE+L++L  YL +     +P I  L+N+TRIH++PSMNPDG+E       
Sbjct: 80  ANMHGDETVGRELLLHLIDYLVTSDGK-DPEITNLINSTRIHIMPSMNPDGFEAVKKPDC 138

Query: 305 GYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLAETRGARSDHIPIPQHYWWGKVAPETKAI 364
            Y+    GR+N    DLNRNFPD   EY  ++                      PET A+
Sbjct: 139 YYS---IGRENYNQYDLNRNFPD-AFEYNNVSRQ--------------------PETVAV 174

Query: 365 MKWMQTIPFVLSASLHGGDLVVSYPFDFSKHPQEEKMF-SPTPDEKMFKLLSRAYADVHP 423
           MKW++T  FVLSA+LHGG LV SYPFD            S TPD+ +F+ L+  YA  +P
Sbjct: 175 MKWLKTETFVLSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNP 234

Query: 424 MMMDRSENRCGGNFLKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVELGCVKFPPEEA 483
            M    E +   NF     + NG  WY   GGM D+NY+   CFEIT+EL C K+P EE 
Sbjct: 235 NMKKGDECKNKMNF--PNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEK 292

Query: 484 LYTLWQHNKESLLNFVETVHRGIKGVVTDKFGKPVKNARISVKGIRH--DITTAPDGDYW 541
           L + W +NK SL+ +++ VH G+KG V D+ G P+ N  + V+  +H     T   G+Y+
Sbjct: 293 LPSFWNNNKASLIEYIKQVHLGVKGQVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYY 352

Query: 542 RLLPPGIHIVIAQAPGYAKVIKKVIIPAR 570
            LL PG +I+    PG+   I KVIIP +
Sbjct: 353 LLLLPGSYIINVTVPGHDPHITKVIIPEK 381


>gi|38327526 carboxypeptidase M precursor [Homo sapiens]
          Length = 443

 Score =  266 bits (681), Expect = 3e-71
 Identities = 153/389 (39%), Positives = 212/389 (54%), Gaps = 30/389 (7%)

Query: 185 FSHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPEVKLI 244
           F++H    M   L+  A   + V   +SIG+S  GR L V+     P +H +  PE K +
Sbjct: 20  FNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYV 79

Query: 245 GNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGA 304
            N+HG+E  GRE+L++L  YL +     +P I  L+N+TRIH++PSMNPDG+E       
Sbjct: 80  ANMHGDETVGRELLLHLIDYLVTSDGK-DPEITNLINSTRIHIMPSMNPDGFEAVKKPDC 138

Query: 305 GYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLAETRGARSDHIPIPQHYWWGKVAPETKAI 364
            Y+    GR+N    DLNRNFPD   EY  ++                      PET A+
Sbjct: 139 YYS---IGRENYNQYDLNRNFPD-AFEYNNVSRQ--------------------PETVAV 174

Query: 365 MKWMQTIPFVLSASLHGGDLVVSYPFDFSKHPQEEKMF-SPTPDEKMFKLLSRAYADVHP 423
           MKW++T  FVLSA+LHGG LV SYPFD            S TPD+ +F+ L+  YA  +P
Sbjct: 175 MKWLKTETFVLSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNP 234

Query: 424 MMMDRSENRCGGNFLKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVELGCVKFPPEEA 483
            M    E +   NF     + NG  WY   GGM D+NY+   CFEIT+EL C K+P EE 
Sbjct: 235 NMKKGDECKNKMNF--PNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEK 292

Query: 484 LYTLWQHNKESLLNFVETVHRGIKGVVTDKFGKPVKNARISVKGIRH--DITTAPDGDYW 541
           L + W +NK SL+ +++ VH G+KG V D+ G P+ N  + V+  +H     T   G+Y+
Sbjct: 293 LPSFWNNNKASLIEYIKQVHLGVKGQVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYY 352

Query: 542 RLLPPGIHIVIAQAPGYAKVIKKVIIPAR 570
            LL PG +I+    PG+   I KVIIP +
Sbjct: 353 LLLLPGSYIINVTVPGHDPHITKVIIPEK 381


>gi|6631081 carboxypeptidase M precursor [Homo sapiens]
          Length = 443

 Score =  266 bits (681), Expect = 3e-71
 Identities = 153/389 (39%), Positives = 212/389 (54%), Gaps = 30/389 (7%)

Query: 185 FSHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPEVKLI 244
           F++H    M   L+  A   + V   +SIG+S  GR L V+     P +H +  PE K +
Sbjct: 20  FNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYV 79

Query: 245 GNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGA 304
            N+HG+E  GRE+L++L  YL +     +P I  L+N+TRIH++PSMNPDG+E       
Sbjct: 80  ANMHGDETVGRELLLHLIDYLVTSDGK-DPEITNLINSTRIHIMPSMNPDGFEAVKKPDC 138

Query: 305 GYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLAETRGARSDHIPIPQHYWWGKVAPETKAI 364
            Y+    GR+N    DLNRNFPD   EY  ++                      PET A+
Sbjct: 139 YYS---IGRENYNQYDLNRNFPD-AFEYNNVSRQ--------------------PETVAV 174

Query: 365 MKWMQTIPFVLSASLHGGDLVVSYPFDFSKHPQEEKMF-SPTPDEKMFKLLSRAYADVHP 423
           MKW++T  FVLSA+LHGG LV SYPFD            S TPD+ +F+ L+  YA  +P
Sbjct: 175 MKWLKTETFVLSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNP 234

Query: 424 MMMDRSENRCGGNFLKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVELGCVKFPPEEA 483
            M    E +   NF     + NG  WY   GGM D+NY+   CFEIT+EL C K+P EE 
Sbjct: 235 NMKKGDECKNKMNF--PNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEK 292

Query: 484 LYTLWQHNKESLLNFVETVHRGIKGVVTDKFGKPVKNARISVKGIRH--DITTAPDGDYW 541
           L + W +NK SL+ +++ VH G+KG V D+ G P+ N  + V+  +H     T   G+Y+
Sbjct: 293 LPSFWNNNKASLIEYIKQVHLGVKGQVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYY 352

Query: 542 RLLPPGIHIVIAQAPGYAKVIKKVIIPAR 570
            LL PG +I+    PG+   I KVIIP +
Sbjct: 353 LLLLPGSYIINVTVPGHDPHITKVIIPEK 381


>gi|4503827 frizzled 2 [Homo sapiens]
          Length = 565

 Score = 70.1 bits (170), Expect = 6e-12
 Identities = 47/145 (32%), Positives = 68/145 (46%), Gaps = 12/145 (8%)

Query: 6   PLLLLTVLVVAAARPGCEFERNPAGECHRPPAADSATCVDLQLRTCSDAAYNHTTFPNLL 65
           P LLL +L++ AA P  +F              D   C  + +  C+D AYN T  PNLL
Sbjct: 8   PRLLLPLLLLPAAGPA-QFHGEKGISI-----PDHGFCQPISIPLCTDIAYNQTIMPNLL 61

Query: 66  QHRSWEVVEASSEYILLSVLHQLLEGQCNPDLRLLGCAVLAPRCEG-GWVRRPCRHICEG 124
            H + E  +A  E   +   + L++ QC+P+LR   C++ AP C        PCR ICE 
Sbjct: 62  GHTNQE--DAGLE---VHQFYPLVKVQCSPELRFFLCSMYAPVCTVLEQAIPPCRSICER 116

Query: 125 LREVCQPAFDAIDMAWPYFLDCHRY 149
            R+ C+   +     WP  L C  +
Sbjct: 117 ARQGCEALMNKFGFQWPERLRCEHF 141


>gi|8393378 frizzled 3 [Homo sapiens]
          Length = 666

 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 37/124 (29%), Positives = 56/124 (45%), Gaps = 11/124 (8%)

Query: 42  TCVDLQLRTCSDAAYNHTTFPNLLQHRSWEVVEASSEYILLSVLHQLLEGQCNPDLRLLG 101
           +C  + LR C D  YN T  PNLL H      +  +  + +   H ++   C+ D R   
Sbjct: 27  SCEPITLRMCQDLPYNTTFMPNLLNH-----YDQQTAALAMEPFHPMVNLDCSRDFRPFL 81

Query: 102 CAVLAPRC-EGGWVRRPCRHICEGLREVCQPAFDAIDMAWPYFLDCHRYFTREDEGCYDP 160
           CA+ AP C E G V  PCR +C+     C    +   + WP  ++C R+       C +P
Sbjct: 82  CALYAPICMEYGRVTLPCRRLCQRAYSECSKLMEMFGVPWPEDMECSRF-----PDCDEP 136

Query: 161 LEKL 164
             +L
Sbjct: 137 YPRL 140


>gi|4503833 frizzled 7 [Homo sapiens]
          Length = 574

 Score = 67.4 bits (163), Expect = 4e-11
 Identities = 37/112 (33%), Positives = 55/112 (49%), Gaps = 6/112 (5%)

Query: 39  DSATCVDLQLRTCSDAAYNHTTFPNLLQHRSWEVVEASSEYILLSVLHQLLEGQCNPDLR 98
           D   C  + +  C+D AYN T  PNLL H + E  +A  E   +   + L++ QC+P+LR
Sbjct: 45  DHGFCQPISIPLCTDIAYNQTILPNLLGHTNQE--DAGLE---VHQFYPLVKVQCSPELR 99

Query: 99  LLGCAVLAPRCEG-GWVRRPCRHICEGLREVCQPAFDAIDMAWPYFLDCHRY 149
              C++ AP C        PCR +CE  R+ C+   +     WP  L C  +
Sbjct: 100 FFLCSMYAPVCTVLDQAIPPCRSLCERARQGCEALMNKFGFQWPERLRCENF 151


>gi|188528609 secreted frizzled-related protein 5 [Homo sapiens]
          Length = 317

 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 36/110 (32%), Positives = 55/110 (50%), Gaps = 10/110 (9%)

Query: 43  CVDL--QLRTCSDAAYNHTTFPNLLQHRSW-EVVEASSEYILLSVLHQLLEGQCNPDLRL 99
           C+D+   L  C    Y     PNLL+H S  EV + +S ++       LL  +C+ D ++
Sbjct: 53  CLDIPADLPLCHTVGYKRMRLPNLLEHESLAEVKQQASSWL------PLLAKRCHSDTQV 106

Query: 100 LGCAVLAPRCEGGWVRRPCRHICEGLREVCQPAFDAIDMAWPYFLDCHRY 149
             C++ AP C    +  PCR +CE +R  C P  +A    WP  L CH++
Sbjct: 107 FLCSLFAPVCLDRPIY-PCRSLCEAVRAGCAPLMEAYGFPWPEMLHCHKF 155


>gi|6005762 frizzled 10 [Homo sapiens]
          Length = 581

 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 56/191 (29%), Positives = 77/191 (40%), Gaps = 21/191 (10%)

Query: 2   PPPPPLLLLTVLVVAAARPGCEFERNPAGECHRPPAADSATCVDLQLRTCSDAAYNHTTF 61
           P P   L+L V+   AA    + ER   G+C             +++  C D  YN T  
Sbjct: 4   PGPRLWLVLQVMGSCAAISSMDMERPGDGKCQ-----------PIEIPMCKDIGYNMTRM 52

Query: 62  PNLLQHRSWEVVEASSEYILLSVLHQLLEGQCNPDLRLLGCAVLAPRCEGGWVRRP---C 118
           PNL+ H +    EA+   I L     L+E  C+  LR   C++ AP C    V  P   C
Sbjct: 53  PNLMGHENQR--EAA---IQLHEFAPLVEYGCHGHLRFFLCSLYAPMCTEQ-VSTPIPAC 106

Query: 119 RHICEGLREVCQPAFDAIDMAWPYFLDCHRYFTREDEGCYDPLEKLRGGLEADEALPSGL 178
           R +CE  R  C P  +  +  WP  LDC +   + D   Y  +E    G +         
Sbjct: 107 RVMCEQARLKCSPIMEQFNFKWPDSLDCRKLPNKNDPN-YLCMEAPNNGSDEPTRGSGLF 165

Query: 179 PPTFIRFSHHS 189
           PP F     HS
Sbjct: 166 PPLFRPQRPHS 176


>gi|27894385 frizzled 5 precursor [Homo sapiens]
          Length = 585

 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 45/152 (29%), Positives = 63/152 (41%), Gaps = 27/152 (17%)

Query: 2   PPPPPLLLLTVLVVAAARPGCEFERNPAGECHRPPAADSATCVDLQLRTCSDAAYNHTTF 61
           P  PP LLL +L     R                 A+ +  C ++ +  C    YN T  
Sbjct: 6   PSAPPSLLLLLLAQLVGRAAA--------------ASKAPVCQEITVPMCRGIGYNLTHM 51

Query: 62  PNLLQHRSWEVVEASSEYILLSVLHQ---LLEGQCNPDLRLLGCAVLAPRCEGGWVRR-- 116
           PN   H + +  EA  E      +HQ   L+E QC+PDLR   C++  P C   + +   
Sbjct: 52  PNQFNHDTQD--EAGLE------VHQFWPLVEIQCSPDLRFFLCSMYTPICLPDYHKPLP 103

Query: 117 PCRHICEGLREVCQPAFDAIDMAWPYFLDCHR 148
           PCR +CE  +  C P       AWP  + C R
Sbjct: 104 PCRSVCERAKAGCSPLMRQYGFAWPERMSCDR 135


>gi|4503825 frizzled 1 [Homo sapiens]
          Length = 647

 Score = 64.3 bits (155), Expect = 3e-10
 Identities = 35/112 (31%), Positives = 55/112 (49%), Gaps = 6/112 (5%)

Query: 39  DSATCVDLQLRTCSDAAYNHTTFPNLLQHRSWEVVEASSEYILLSVLHQLLEGQCNPDLR 98
           D   C  + +  C+D AYN T  PNLL H + E  +A  E   +   + L++ QC+ +L+
Sbjct: 112 DHGYCQPISIPLCTDIAYNQTIMPNLLGHTNQE--DAGLE---VHQFYPLVKVQCSAELK 166

Query: 99  LLGCAVLAPRCEG-GWVRRPCRHICEGLREVCQPAFDAIDMAWPYFLDCHRY 149
              C++ AP C        PCR +CE  R+ C+   +     WP  L C ++
Sbjct: 167 FFLCSMYAPVCTVLEQALPPCRSLCERARQGCEALMNKFGFQWPDTLKCEKF 218


>gi|34734079 frizzled 6 [Homo sapiens]
          Length = 706

 Score = 63.9 bits (154), Expect = 4e-10
 Identities = 34/108 (31%), Positives = 48/108 (44%), Gaps = 6/108 (5%)

Query: 42  TCVDLQLRTCSDAAYNHTTFPNLLQHRSWEVVEASSEYILLSVLHQLLEGQCNPDLRLLG 101
           TC  + +  C   AYN T FPNL+ H    +     E+ L      L   +C+P++    
Sbjct: 23  TCEPITVPRCMKMAYNMTFFPNLMGHYDQSIAAVEMEHFL-----PLANLECSPNIETFL 77

Query: 102 CAVLAPRC-EGGWVRRPCRHICEGLREVCQPAFDAIDMAWPYFLDCHR 148
           C    P C E   V  PCR +CE +   C+   D   + WP  L+C R
Sbjct: 78  CKAFVPTCIEQIHVVPPCRKLCEKVYSDCKKLIDTFGIRWPEELECDR 125


>gi|4503835 frizzled 9 [Homo sapiens]
          Length = 591

 Score = 63.9 bits (154), Expect = 4e-10
 Identities = 42/118 (35%), Positives = 57/118 (48%), Gaps = 9/118 (7%)

Query: 40  SATCVDLQLRTCSDAAYNHTTFPNLLQHRSWEVVEASSEYILLSVLHQLLEGQCNPDLRL 99
           +A C  +++  C    YN T  PNLL H S    EA++E   L+    L++  C+  LR 
Sbjct: 36  AAPCQAVEIPMCRGIGYNLTRMPNLLGHTSQG--EAAAE---LAEFAPLVQYGCHSHLRF 90

Query: 100 LGCAVLAPRCEGGWVRRP---CRHICEGLREVCQPAFDAIDMAWPYFLDCHRYFTRED 154
             C++ AP C    V  P   CR +CE  R  C P  +  +  WP  LDC R  TR D
Sbjct: 91  FLCSLYAPMCTDQ-VSTPIPACRPMCEQARLRCAPIMEQFNFGWPDSLDCARLPTRND 147


>gi|56117838 secreted frizzled-related protein 1 [Homo sapiens]
          Length = 314

 Score = 63.5 bits (153), Expect = 6e-10
 Identities = 34/110 (30%), Positives = 54/110 (49%), Gaps = 10/110 (9%)

Query: 43  CVDL--QLRTCSDAAYNHTTFPNLLQHRSW-EVVEASSEYILLSVLHQLLEGQCNPDLRL 99
           CVD+   LR C +  Y     PNLL+H +  EV + +S ++       LL   C+   ++
Sbjct: 58  CVDIPADLRLCHNVGYKKMVLPNLLEHETMAEVKQQASSWV------PLLNKNCHAGTQV 111

Query: 100 LGCAVLAPRCEGGWVRRPCRHICEGLREVCQPAFDAIDMAWPYFLDCHRY 149
             C++ AP C    +  PCR +CE +R+ C+P        WP  L C ++
Sbjct: 112 FLCSLFAPVCLDRPIY-PCRWLCEAVRDSCEPVMQFFGFYWPEMLKCDKF 160


>gi|29244926 corin [Homo sapiens]
          Length = 1042

 Score = 63.5 bits (153), Expect = 6e-10
 Identities = 32/109 (29%), Positives = 51/109 (46%), Gaps = 5/109 (4%)

Query: 43  CVDLQLRTCSDAAYNHTTFPNLLQHRSWEVVEASSEYILLSVLHQLLEGQCNPDLRLLGC 102
           C  + L  C +  YN T++PN   HR+ +    S E    S+   L++  C   L    C
Sbjct: 455 CEPITLELCMNLPYNSTSYPNYFGHRTQKEASISWES---SLFPALVQTNCYKYLMFFSC 511

Query: 103 AVLAPRCE--GGWVRRPCRHICEGLREVCQPAFDAIDMAWPYFLDCHRY 149
            +L P+C+   G    PCR +CE  +E C+     + + WP   DC ++
Sbjct: 512 TILVPKCDVNTGEHIPPCRALCEHSKERCESVLGIVGLQWPEDTDCSQF 560



 Score = 53.1 bits (126), Expect = 8e-07
 Identities = 34/145 (23%), Positives = 63/145 (43%), Gaps = 19/145 (13%)

Query: 28  PAGECHRPPAADSATCVDLQLRTCSDAAYNHTTFPNLLQHRSWEVVEASSEYILLSVLHQ 87
           P  + HR    +++ C+++    C    Y+ T  P L   R+ E+ +    +   + LH+
Sbjct: 128 PGDQSHR----NTSACMNITHSQCQMLPYHATLTPLLSVVRNMEMEKFLKFF---TYLHR 180

Query: 88  LLEGQCNPDLRLLGCAVLAPRC----EGGWVRRPCRHICEGLREVCQPAFDAIDMAWPYF 143
           L    C   + L GC +  P C    +      PCR  CE  +E C+     ++ +WP F
Sbjct: 181 L---SCYQHIMLFGCTLAFPECIIDGDDSHGLLPCRSFCEAAKEGCESVLGMVNYSWPDF 237

Query: 144 LDCHRYFTREDEG-----CYDPLEK 163
           L C ++  + +       C+ P ++
Sbjct: 238 LRCSQFRNQTESSNVSRICFSPQQE 262


>gi|38455388 frizzled-related protein [Homo sapiens]
          Length = 325

 Score = 63.2 bits (152), Expect = 7e-10
 Identities = 36/130 (27%), Positives = 56/130 (43%), Gaps = 8/130 (6%)

Query: 34  RPPAADSATCVDLQLRTCSDAAYNHTTFPNLLQHRSWEVVEASSEYILLSVLHQLLEGQC 93
           R P A +A C  +++  C    +N T  PN L H +      ++  + +     LL   C
Sbjct: 26  RVPGARAAACEPVRIPLCKSLPWNMTKMPNHLHHST-----QANAILAIEQFEGLLGTHC 80

Query: 94  NPDLRLLGCAVLAPRCEGGWVR---RPCRHICEGLREVCQPAFDAIDMAWPYFLDCHRYF 150
           +PDL    CA+ AP C   +     +PC+ +CE  R+ C+P       +WP  L C    
Sbjct: 81  SPDLLFFLCAMYAPICTIDFQHEPIKPCKSVCERARQGCEPILIKYRHSWPENLACEELP 140

Query: 151 TREDEGCYDP 160
             +   C  P
Sbjct: 141 VYDRGVCISP 150


>gi|48475052 secreted frizzled-related protein 2 precursor [Homo
           sapiens]
          Length = 295

 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 40/135 (29%), Positives = 63/135 (46%), Gaps = 11/135 (8%)

Query: 44  VDLQLRTCSDAAYNHTTFPNLLQHRSW-EVVEASSEYILLSVLHQLLEGQCNPDLRLLGC 102
           +   L+ C    Y +   PNLL H +  EV+E +  +I       L+  QC+PD +   C
Sbjct: 43  IPANLQLCHGIEYQNMRLPNLLGHETMKEVLEQAGAWI------PLVMKQCHPDTKKFLC 96

Query: 103 AVLAPRC--EGGWVRRPCRHICEGLREVCQPAFDAIDMAWPYFLDCHRYFTREDEGCYDP 160
           ++ AP C  +     +PC  +C  +++ C P   A    WP  L+C R F ++++ C  P
Sbjct: 97  SLFAPVCLDDLDETIQPCHSLCVQVKDRCAPVMSAFGFPWPDMLECDR-FPQDNDLCI-P 154

Query: 161 LEKLRGGLEADEALP 175
           L      L A E  P
Sbjct: 155 LASSDHLLPATEEAP 169


>gi|13994190 frizzled 8 [Homo sapiens]
          Length = 694

 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 36/117 (30%), Positives = 54/117 (46%), Gaps = 13/117 (11%)

Query: 37  AADSATCVDLQLRTCSDAAYNHTTFPNLLQHRSWEVVEASSEYILLSVLHQ---LLEGQC 93
           +A    C ++ +  C    YN+T  PN   H + +  EA  E      +HQ   L+E QC
Sbjct: 29  SAKELACQEITVPLCKGIGYNYTYMPNQFNHDTQD--EAGLE------VHQFWPLVEIQC 80

Query: 94  NPDLRLLGCAVLAPRCEGGWVRR--PCRHICEGLREVCQPAFDAIDMAWPYFLDCHR 148
           +PDL+   C++  P C   + +   PCR +CE  +  C P       AWP  + C R
Sbjct: 81  SPDLKFFLCSMYTPICLEDYKKPLPPCRSVCERAKAGCAPLMRQYGFAWPDRMRCDR 137


>gi|13899255 membrane frizzled-related protein [Homo sapiens]
          Length = 579

 Score = 60.1 bits (144), Expect = 6e-09
 Identities = 45/138 (32%), Positives = 58/138 (42%), Gaps = 15/138 (10%)

Query: 27  NPAGECHRPPAADSATCVDLQLRTCSDAAYNHTTFPNLL--QHRSWEVVEASSEYILLSV 84
           N +G    PP      C  +Q+  C   +YN T FPN+        EVVE  S Y  L+ 
Sbjct: 453 NCSGPLFPPP---ELACEPVQVEMCLGLSYNTTAFPNIWVGMITQEEVVEVLSGYKSLTS 509

Query: 85  LHQLLEGQCNPDLRLLGCAVLAPRCEG-GWVRRPCRHICEGLREVCQPAFDAIDMAWPYF 143
           L       C    R L C +L PRC   G V  PCR +C+     CQ     +   WP+ 
Sbjct: 510 L------PCYQHFRRLLCGLLVPRCTPLGSVLPPCRSVCQEAEHQCQSGLALLGTPWPF- 562

Query: 144 LDCHRYFTRED-EGCYDP 160
            +C+R     D E C  P
Sbjct: 563 -NCNRLPEAADLEACAQP 579


>gi|61743916 carboxypeptidase A4 preproprotein [Homo sapiens]
          Length = 421

 Score = 60.1 bits (144), Expect = 6e-09
 Identities = 61/241 (25%), Positives = 102/241 (42%), Gaps = 22/241 (9%)

Query: 186 SHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPEVKLIG 245
           ++HS   +   +   A+    +AR   IG SF+ R + V++FS+  G   +  P V L  
Sbjct: 122 AYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGKG---VRRPAVWLNA 178

Query: 246 NIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGAG 305
            IH  E   +   I+ A+ + S+Y   +P I  +L    I LLP  NPDGY     +   
Sbjct: 179 GIHSREWISQATAIWTARKIVSDY-QRDPAITSILEKMDIFLLPVANPDGYVYTQTQNRL 237

Query: 306 YNGWTSGRQNAQ--NLDLNRNFPDLTSEYYRLAETRGARSDHIPIPQHYWWGKVAPETKA 363
           +    S    +     D NRN       +      +GA  +      H        E K+
Sbjct: 238 WRKTRSRNPGSSCIGADPNRN-------WNASFAGKGASDNPCSEVYHGPHANSEVEVKS 290

Query: 364 IMKWMQTI-PFVLSASLHGGDLVVSYPFDFS--KHPQEEKMFSPTPDEKMFKLLSRAYAD 420
           ++ ++Q    F     LH    ++ YP+ +S  K P  E++      +K+ +L ++A A 
Sbjct: 291 VVDFIQKHGNFKGFIDLHSYSQLLMYPYGYSVKKAPDAEEL------DKVARLAAKALAS 344

Query: 421 V 421
           V
Sbjct: 345 V 345


>gi|170784838 secreted frizzled-related  protein 4 [Homo sapiens]
          Length = 346

 Score = 56.2 bits (134), Expect = 9e-08
 Identities = 31/123 (25%), Positives = 55/123 (44%), Gaps = 8/123 (6%)

Query: 41  ATCVDLQLRTCSDAAYNHTTFPNLLQHRSWEVVEASSEYILLSVLHQLLEGQCNPDLRLL 100
           A C  +++  C    +N T  PN L H + E     +  + +    +L++  C+  LR  
Sbjct: 22  APCEAVRIPMCRHMPWNITRMPNHLHHSTQE-----NAILAIEQYEELVDVNCSAVLRFF 76

Query: 101 GCAVLAPRCEGGWVR---RPCRHICEGLREVCQPAFDAIDMAWPYFLDCHRYFTREDEGC 157
            CA+ AP C   ++    +PC+ +C+  R+ C+P     + +WP  L C      +   C
Sbjct: 77  LCAMYAPICTLEFLHDPIKPCKSVCQRARDDCEPLMKMYNHSWPESLACDELPVYDRGVC 136

Query: 158 YDP 160
             P
Sbjct: 137 ISP 139


>gi|22547161 frizzled 4 [Homo sapiens]
          Length = 537

 Score = 53.1 bits (126), Expect = 8e-07
 Identities = 29/114 (25%), Positives = 52/114 (45%), Gaps = 7/114 (6%)

Query: 43  CVDLQLRTCSDAAYNHTTFPNLLQHRSWEVVEASSEYILLSVLHQLLEGQCNPDLRLLGC 102
           C  +++  C +  YN T  PNL+ H     ++  +E + L+    L++  C+  L+   C
Sbjct: 45  CDPIRISMCQNLGYNVTKMPNLVGHE----LQTDAE-LQLTTFTPLIQYGCSSQLQFFLC 99

Query: 103 AVLAPRCEG--GWVRRPCRHICEGLREVCQPAFDAIDMAWPYFLDCHRYFTRED 154
           +V  P C         PC  +C  ++  C+P       AWP  L+C ++  + D
Sbjct: 100 SVYVPMCTEKINIPIGPCGGMCLSVKRRCEPVLKEFGFAWPESLNCSKFPPQND 153


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.139    0.449 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,285,074
Number of Sequences: 37866
Number of extensions: 1455834
Number of successful extensions: 3389
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 3254
Number of HSP's gapped (non-prelim): 61
length of query: 652
length of database: 18,247,518
effective HSP length: 109
effective length of query: 543
effective length of database: 14,120,124
effective search space: 7667227332
effective search space used: 7667227332
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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