Guide to the Human Genome
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Search of human proteins with 55956910

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|55956910 meningioma  1 [Homo sapiens]
         (1320 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|55956910 meningioma  1 [Homo sapiens]                             2762   0.0  
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]     109   2e-23
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...   105   3e-22
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...   105   3e-22
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...   105   3e-22
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ...   105   4e-22
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]     104   6e-22
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]    103   1e-21
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]    103   1e-21
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...   102   3e-21
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...   102   3e-21
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...    97   1e-19
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...    97   1e-19
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...    97   1e-19
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ...    97   1e-19
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]       94   7e-19
gi|22027597 alpha 1 type XIII collagen isoform 13 [Homo sapiens]       94   7e-19
gi|22027580 alpha 1 type XIII collagen isoform 6 [Homo sapiens]        94   7e-19
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]       94   9e-19
gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]         93   1e-18
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ...    93   1e-18
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    92   4e-18
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]    91   6e-18
gi|194294532 alpha 1 type XIII collagen isoform 20 [Homo sapiens]      91   6e-18
gi|22027583 alpha 1 type XIII collagen isoform 7 [Homo sapiens]        91   7e-18
gi|22027565 alpha 1 type XIII collagen isoform 1 [Homo sapiens]        91   7e-18
gi|22027587 alpha 1 type XIII collagen isoform 8 [Homo sapiens]        91   7e-18
gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]      91   1e-17
gi|55750053 atrophin-1 [Homo sapiens]                                  89   3e-17
gi|55750041 atrophin-1 [Homo sapiens]                                  89   3e-17

>gi|55956910 meningioma  1 [Homo sapiens]
          Length = 1320

 Score = 2762 bits (7160), Expect = 0.0
 Identities = 1320/1320 (100%), Positives = 1320/1320 (100%)

Query: 1    MFGLDQFEPQVNSRNAGQGERNFNETGLSMNTHFKAPAFHTGGPPGPVDPAMSALGEPPI 60
            MFGLDQFEPQVNSRNAGQGERNFNETGLSMNTHFKAPAFHTGGPPGPVDPAMSALGEPPI
Sbjct: 1    MFGLDQFEPQVNSRNAGQGERNFNETGLSMNTHFKAPAFHTGGPPGPVDPAMSALGEPPI 60

Query: 61   LGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHGHPGSHHPHQHHPHFGGNFGG 120
            LGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHGHPGSHHPHQHHPHFGGNFGG
Sbjct: 61   LGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHGHPGSHHPHQHHPHFGGNFGG 120

Query: 121  PDPGASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHMAESQGPESFGPQRPGNLPDFHSSG 180
            PDPGASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHMAESQGPESFGPQRPGNLPDFHSSG
Sbjct: 121  PDPGASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHMAESQGPESFGPQRPGNLPDFHSSG 180

Query: 181  ASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAP 240
            ASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAP
Sbjct: 181  ASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAP 240

Query: 241  SGHFDMFSPSDSEGQLPHYAAGRQVPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQ 300
            SGHFDMFSPSDSEGQLPHYAAGRQVPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQ
Sbjct: 241  SGHFDMFSPSDSEGQLPHYAAGRQVPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQ 300

Query: 301  QQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQ 360
            QQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQ
Sbjct: 301  QQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQ 360

Query: 361  PPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMH 420
            PPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMH
Sbjct: 361  PPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMH 420

Query: 421  PYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNG 480
            PYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNG
Sbjct: 421  PYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNG 480

Query: 481  ALDNHLSPSAYPGLPGEFTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQ 540
            ALDNHLSPSAYPGLPGEFTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQ
Sbjct: 481  ALDNHLSPSAYPGLPGEFTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQ 540

Query: 541  QQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQ 600
            QQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQ
Sbjct: 541  QQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQ 600

Query: 601  PNFEREGGSTGAGRLGTFEQQAPHLAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPHD 660
            PNFEREGGSTGAGRLGTFEQQAPHLAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPHD
Sbjct: 601  PNFEREGGSTGAGRLGTFEQQAPHLAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPHD 660

Query: 661  PSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGVG 720
            PSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGVG
Sbjct: 661  PSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGVG 720

Query: 721  LPSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGG 780
            LPSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGG
Sbjct: 721  LPSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGG 780

Query: 781  GGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLG 840
            GGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLG
Sbjct: 781  GGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLG 840

Query: 841  APNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSG 900
            APNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSG
Sbjct: 841  APNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSG 900

Query: 901  SKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFD 960
            SKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFD
Sbjct: 901  SKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFD 960

Query: 961  KYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGD 1020
            KYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGD
Sbjct: 961  KYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGD 1020

Query: 1021 QPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTG 1080
            QPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTG
Sbjct: 1021 QPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTG 1080

Query: 1081 SPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTS 1140
            SPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTS
Sbjct: 1081 SPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTS 1140

Query: 1141 SSGAPPPDEIHPLEILQAQIQLQRQQFSISEDQPLGLKGGKKGECAVGASGAQNGDSELG 1200
            SSGAPPPDEIHPLEILQAQIQLQRQQFSISEDQPLGLKGGKKGECAVGASGAQNGDSELG
Sbjct: 1141 SSGAPPPDEIHPLEILQAQIQLQRQQFSISEDQPLGLKGGKKGECAVGASGAQNGDSELG 1200

Query: 1201 SCCSEAVKSAMSTIDLDSLMAEHSAAWYMPADKALVDSADDDKTLAPWEKAKPQNPNSKE 1260
            SCCSEAVKSAMSTIDLDSLMAEHSAAWYMPADKALVDSADDDKTLAPWEKAKPQNPNSKE
Sbjct: 1201 SCCSEAVKSAMSTIDLDSLMAEHSAAWYMPADKALVDSADDDKTLAPWEKAKPQNPNSKE 1260

Query: 1261 AHDLPANKASASQPGSHLQCLSVHCTDDVGDAKARASVPTWRSLHSDISNRFGTFVAALT 1320
            AHDLPANKASASQPGSHLQCLSVHCTDDVGDAKARASVPTWRSLHSDISNRFGTFVAALT
Sbjct: 1261 AHDLPANKASASQPGSHLQCLSVHCTDDVGDAKARASVPTWRSLHSDISNRFGTFVAALT 1320


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score =  109 bits (272), Expect = 2e-23
 Identities = 219/868 (25%), Positives = 285/868 (32%), Gaps = 162/868 (18%)

Query: 339  QPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQGEAGTPS-GGLQDGG 397
            QPP     PP  Q PQ P  +  P PPG+  R     P +P  Q G  G+P   G+ +  
Sbjct: 90   QPPTAPTRPPNGQGPQGP--KGDPGPPGIPGRNGD--PGIP-GQPGSPGSPGPPGICESC 144

Query: 398  PMLPSQHAQFEYPIHRLEN----RSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNV 453
            P  P  ++  +Y  + +++      +  Y  P      PP    P     H  +P     
Sbjct: 145  PTGPQNYSP-QYDSYDVKSGVAVGGLAGYPGPA----GPPGPPGPPGTSGHPGSPGSPGY 199

Query: 454  AKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSF--PSGPP 511
               P    PG AG        G++           S  PG PGE   P P     P+G P
Sbjct: 200  QGPP--GEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIP 257

Query: 512  LQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLR 571
                   H+                                           RN ++   
Sbjct: 258  GFPGMKGHRGFD---------------------------------------GRNGEK--- 275

Query: 572  QPNLAQLGHPGDVGQGGLV----HGGPVGGLAQPNFEREGGSTGA-------GRLGTFEQ 620
                 + G PG  G+ GL       GP+G    P      G  GA       G  G+  Q
Sbjct: 276  ----GETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQ 331

Query: 621  QAPHLAQESAWFSGPHPPPGDLLPRRMGGS-GLPADCGP-----HDPSLAPPPPPGGSGV 674
              P     +A F G     G++ P    GS G P   G      H  +  PP PPG +G 
Sbjct: 332  PGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGS 391

Query: 675  LFRGPLQEPMRMPGEGHVPALPSPGLQFG-GSLGGLGQLQSPG--AGVGLPSAASERRPP 731
                    P  +PG        +PGL    G  G  G   +PG   G G P     +  P
Sbjct: 392  PGGKGEMGPAGIPG--------APGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEP 443

Query: 732  PP--DFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQP 789
             P  +   + + G PG   G  G+  +P   PG N  P A G  G+ G  G     P  P
Sbjct: 444  GPRGERGEAGIPGVPGAK-GEDGKDGSP-GEPGANGLPGAAGERGAPGFRG-----PAGP 496

Query: 790  DFQPSQRTSASKLGALS----LGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLN 845
            +  P ++  A + GA       G+  +P  +D + G           + M  S G P  +
Sbjct: 497  NGIPGEKGPAGERGAPGPAGPRGAAGEP-GRDGVPG-------GPGMRGMPGSPGGPGSD 548

Query: 846  VTFNKKNPPEGKRKLSQNETDG-AAVAGNPGSDYFPGGT-------------APGAPGPG 891
                K  PP  + +  +    G +   G PG   FPG                PG PGP 
Sbjct: 549  ---GKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQ 605

Query: 892  GPSGTSSSGSKASGPPNPPAQ-GDGTSLSPNYTLESTSGNDGKPVSGG-----GGRGRGR 945
            GP G +   +   GPP P    GD     P        G  G P +GG     G  G   
Sbjct: 606  GPPGKNGE-TGPQGPPGPTGPGGDKGDTGP----PGPQGLQGLPGTGGPPGENGKPGEPG 660

Query: 946  RKRDSGHVSPGTFFDKYSA-APDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKA 1004
             K D+G  +PG    K  A AP   G PG++       GA   G   G+    P      
Sbjct: 661  PKGDAG--APGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGP------ 712

Query: 1005 LTSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSD 1064
               P    G   L G   +  G    G K D   P  G   +D V               
Sbjct: 713  -PGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEP--GGPGADGVPGKDGPRGPTGPIGP 769

Query: 1065 NPQALVKASRSPLVTGSPKLP----PRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGG 1120
               A     +     G+P LP    PRG   GE G   PP   G          P   G 
Sbjct: 770  PGPAGQPGDKGE--GGAPGLPGIAGPRG-SPGERGETGPPGPAGFPGAPGQNGEPGGKGE 826

Query: 1121 GGGPGHPGTPGLEQVRTPTSSSG-APPP 1147
             G PG  G  G   V  P   SG A PP
Sbjct: 827  RGAPGEKGEGGPPGVAGPPGGSGPAGPP 854



 Score = 98.6 bits (244), Expect = 4e-20
 Identities = 300/1195 (25%), Positives = 368/1195 (30%), Gaps = 215/1195 (17%)

Query: 42   GGPPGPVDPAMSALGEP-PILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPH-- 98
            G P  P  P    + E  P    N  P        S +  GGL   P  G  G   P   
Sbjct: 127  GQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYP--GPAGPPGPPGP 184

Query: 99   ---HGHPGSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLGSQPPFAEGYEH 155
                GHPGS       P + G  G P             G  G +G  G  PP A G   
Sbjct: 185  PGTSGHPGS----PGSPGYQGPPGEP-------------GQAGPSGPPG--PPGAIGPSG 225

Query: 156  MAESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDSH 215
             A   G ES  P RPG              +P P  P  + P     F G+    G D  
Sbjct: 226  PAGKDG-ESGRPGRPGE-----------RGLPGP--PGIKGPAGIPGFPGMKGHRGFDGR 271

Query: 216  SLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQ-----LPHYAAGRQVPGG-- 268
            + E       G     E   PGE  +G      P  + G+     LP  A  R   G   
Sbjct: 272  NGEKGETGAPGLKG--ENGLPGE--NGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARG 327

Query: 269  --AFPGASAMPRAAGMVGLSKMHAQP-PQQQPQQQQQPQQQQQQHGVFFERFSGARKMP- 324
                PG    P  AG  G      +  P   P     P Q+ +      +  +GA+  P 
Sbjct: 328  SDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGP---QGHAGAQGPPG 384

Query: 325  -VGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPP-PPGLLVRQNSCPPAL---- 378
              G+  S G +  +   P   P  P     + PP        PGL  R  +  P      
Sbjct: 385  PPGINGSPGGKGEM--GPAGIPGAPGLMGARGPPGPAGANGAPGL--RGGAGEPGKNGAK 440

Query: 379  ----PRPQQGEAG---TPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQH 431
                PR ++GEAG    P    +DG    P +      P    E R    +  P      
Sbjct: 441  GEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGE-RGAPGFRGPAGPNGI 499

Query: 432  PPPQQAPNQRLQHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAY 491
            P  +    +R     A P     +  R   PG  G+       GS      D    P   
Sbjct: 500  PGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGM---RGMPGSPGGPGSDGKPGP--- 553

Query: 492  PGLPGEFTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQR 551
            PG  GE   P P   PSGP  Q   P        +       +  ++        Q    
Sbjct: 554  PGSQGESGRPGPPG-PSGPRGQ---PGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPG 609

Query: 552  QNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGG-LVHGGPVGGLAQPNFEREGGST 610
            +N                         G PG  G GG     GP G          GG  
Sbjct: 610  KNG-------------------ETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPP 650

Query: 611  GA-GRLGTFEQQAPHLAQESAWFSGPHPPPGDLLPRRMGGS-GLPADCGPHDP-----SL 663
            G  G+ G    +    A  +    G    PG+  P  + G+ GL    GP  P     + 
Sbjct: 651  GENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAA 710

Query: 664  APPPPPGGSGVLF-------RGPLQEPMRM--------PGEGHVPALPSPGLQFG--GSL 706
             PP PPG +G          RG L  P           PG   VP    P    G  G  
Sbjct: 711  GPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPP 770

Query: 707  GGLGQLQSPGAG--VGLPSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVN 764
            G  GQ    G G   GLP  A  R  P     T    G  GFP GA G+   P  G G  
Sbjct: 771  GPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGP-PGPAGFP-GAPGQNGEP-GGKGER 827

Query: 765  SPPSAGGGGGSSG----GGGGGGAYPPQPDFQPSQRTSASKLGALSL----GSFNKPSSK 816
              P   G GG  G     GG G A PP P     +R S    GA       G    P S 
Sbjct: 828  GAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSN 887

Query: 817  DNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAV----AG 872
             N                     G P  + +  K  PP          + G +     AG
Sbjct: 888  GNP--------------------GPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAG 927

Query: 873  NPGSDYFPGGTAP-GAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGND 931
             PG    PG   P GAPGP G +G + +   A GPP  P  G   S  P    +   G  
Sbjct: 928  QPGEKGSPGAQGPPGAPGPLGIAGITGARGLA-GPPGMP--GPRGSPGP----QGVKGES 980

Query: 932  GKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSA 991
            GKP + G    RG           GT     +  P   G PG S G     G+  G    
Sbjct: 981  GKPGANGLSGERGPPGPQGLPGLAGT-----AGEPGRDGNPG-SDGLPGRDGSPGGKGDR 1034

Query: 992  GETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVST 1051
            GE      P       P    G     GD+ +       G    + +P  G   S     
Sbjct: 1035 GENGSPGAPGAPGHPGPPGPVGPAGKSGDRGE------SGPAGPAGAP--GPAGSRGAPG 1086

Query: 1052 SYANEDEVSSSSDNPQALVKASRS-PLVTGSPKLP-PRG----VGA-------GEHGPKA 1098
                  +   + +   A +K  R  P   G+P  P P G    +G+       G  GP  
Sbjct: 1087 PQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSG 1146

Query: 1099 PPPALGLGIMSNSTSTP------DSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPP 1147
            PP   G          P         G  G PGHPG PG      P    GAP P
Sbjct: 1147 PPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPG------PPGPPGAPGP 1195



 Score = 97.1 bits (240), Expect = 1e-19
 Identities = 163/603 (27%), Positives = 198/603 (32%), Gaps = 126/603 (20%)

Query: 579  GHPGDVGQGGLVHG-GPVGGLAQPNFEREGGSTGAGRLGTFEQQAPHLAQESAWFSGPHP 637
            G PG  G+ G     GP G   QP      G  G          AP    E     GP P
Sbjct: 552  GPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKG-------NDGAPGKNGERGGPGGPGP 604

Query: 638  --PPGDLLPRRMGGSGLPADCGPHDPS--LAPPPPPGGSGVLFRGPLQEPMRMPGEGHVP 693
              PPG       G  G P   GP        PP P G  G+   G        PGE   P
Sbjct: 605  QGPPGK--NGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGG------PPGENGKP 656

Query: 694  ALPSPGLQFG--GSLGGLGQLQSPGAG-----VGLPSAASERRPPPPDFATSALGGQPGF 746
              P P    G  G+ GG G   +PG        G P       PP P+    A G  P  
Sbjct: 657  GEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAG--PPG 714

Query: 747  PFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGGGGAYP-PQPDFQPSQRTSASKLGAL 805
            P GAAG        PG+   P   GG GS G  G  G    P  D  P +       G +
Sbjct: 715  PPGAAGT-------PGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPI 767

Query: 806  SL-GSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNE 864
               G   +P  K    G+                 GAP L      +  P G+R      
Sbjct: 768  GPPGPAGQPGDK----GEG----------------GAPGLPGIAGPRGSP-GERG-ETGP 805

Query: 865  TDGAAVAGNPGSDYFPGGT----APGAPGPGGPSGTSS--SGSKASGPPNPPAQGDGTSL 918
               A   G PG +  PGG     APG  G GGP G +    GS  +GPP P  QG     
Sbjct: 806  PGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGP--QG----- 858

Query: 919  SPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVS--P 976
                 ++   G+ G P + G    RG       + +PG         P   G+PG    P
Sbjct: 859  -----VKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGP--------PGPSGSPGKDGPP 905

Query: 977  GQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSDS 1036
            G    +GA      +G    A  P EK         GA   LG     I  + G A+  +
Sbjct: 906  GPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLG-----IAGITG-ARGLA 959

Query: 1037 SSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGP 1096
              P +                     S  PQ +   S  P   G          +GE GP
Sbjct: 960  GPPGMPG----------------PRGSPGPQGVKGESGKPGANGL---------SGERGP 994

Query: 1097 KAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAP-------PPDE 1149
              P    GL   +       + G  G PG  G+PG +  R    S GAP       PP  
Sbjct: 995  PGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGP 1054

Query: 1150 IHP 1152
            + P
Sbjct: 1055 VGP 1057



 Score = 72.4 bits (176), Expect = 3e-12
 Identities = 252/1055 (23%), Positives = 321/1055 (30%), Gaps = 192/1055 (18%)

Query: 43   GPPGPVDPAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQP-----VHGFFG---- 93
            G PGP+ P     G P   G    P    ARG+        Q  P       GF G    
Sbjct: 294  GAPGPMGPR----GAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGA 349

Query: 94   -GQQPHHGHPGSHH-PHQH-HPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLGSQPPFA 150
             G+    G PGS+  P Q   P   G+ G   P           G  G+ GG G   P  
Sbjct: 350  KGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPP-------GINGSPGGKGEMGPAG 402

Query: 151  -EGYEHMAESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSS 209
              G   +  ++GP   GP      P             A   P  +     A   G+P +
Sbjct: 403  IPGAPGLMGARGPP--GPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGA 460

Query: 210  SGSDSHSLEPRRVTNQGAVDSL-EYNYPG----EAPSGHFDMFSPSDSEGQL----PHYA 260
             G D     P      G   +  E   PG      P+G      P+   G      P  A
Sbjct: 461  KGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGA 520

Query: 261  AGRQ----VPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQ----PQQQQQQHGV 312
            AG      VPGG  PG   MP + G  G S     PP  Q +  +     P   + Q GV
Sbjct: 521  AGEPGRDGVPGG--PGMRGMPGSPGGPG-SDGKPGPPGSQGESGRPGPPGPSGPRGQPGV 577

Query: 313  FFERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQN 372
                F G    P G + + G       P    P  P  +  +  PQ  PP P G    + 
Sbjct: 578  M--GFPG----PKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQG-PPGPTGPGGDKG 630

Query: 373  SCPPALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHP 432
               P  P+  QG  GT     ++G P  P        P       +     +     +  
Sbjct: 631  DTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAP------GAPGGKGDAGAPGERG 684

Query: 433  PPQQAPNQRLQHFDAPPYMNVAKRPRFDF--PGSAGVDRCASWNGSMHNGALDNHLSPSA 490
            PP  A    L+    PP     K        PG+AG        G               
Sbjct: 685  PPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKG 744

Query: 491  YPGLPGEFTPPVPDSFPSGP--PLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQ 548
             PG PG    P  D  P GP  P+  P P                        Q   + +
Sbjct: 745  EPGGPGADGVPGKDG-PRGPTGPIGPPGP----------------------AGQPGDKGE 781

Query: 549  QQRQNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGG 608
                    +     S  ++     P  A  G PG  GQ G    G  G    P  + EGG
Sbjct: 782  GGAPGLPGIAGPRGSPGERGETGPPGPA--GFPGAPGQNG--EPGGKGERGAPGEKGEGG 837

Query: 609  STGA-------------GRLGTFEQQAPHLAQESAWFSG----PHPPPGDLLPRRMGGSG 651
              G              G  G   ++       +A F G    P PP  +  P   G SG
Sbjct: 838  PPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSG 897

Query: 652  LPADCGPHDPS--LAPPPPPGGSGVLFRGPLQEPMRM--PGEGHVPALPSPGLQFGGSLG 707
             P   GP  P+     P  PG SG   +G   +P     PG    P  P P L   G  G
Sbjct: 898  SPGKDGPPGPAGNTGAPGSPGVSGP--KGDAGQPGEKGSPGAQGPPGAPGP-LGIAGITG 954

Query: 708  GLGQLQSPGA----------GV----GLPSA---ASERRPPPPDFATSALG--------G 742
              G    PG           GV    G P A   + ER PP P       G        G
Sbjct: 955  ARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDG 1014

Query: 743  QPGFPFGAAGRQSTP-------------------HSGP-GVNSPPSAGGGGGSSGGGGGG 782
             PG   G  GR  +P                   H GP G   P    G  G SG  G  
Sbjct: 1015 NPGSD-GLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPA 1073

Query: 783  GAYPPQ-------PDFQPSQRTSASKLGALSL-------GSFNKPSSKDNLFGQSCLAAL 828
            GA  P        P      +    + GA  +       G+   P S      Q  + + 
Sbjct: 1074 GAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSP 1133

Query: 829  STAC-QNMIASLGAPNLNVTFNKKNP-----PEGKRKLSQNETDGA-AVAGNPGSDYFPG 881
              A  +  +   G P  + T     P     P G R   +  ++G+    G PG    PG
Sbjct: 1134 GPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNR--GERGSEGSPGHPGQPGPPGPPG 1191

Query: 882  GTAPGAPGPGGPSGTSSSGSKASGPPNPPAQGDG------TSLSPNYTLESTSGNDGKPV 935
               P   G G  +     G KA G    P  GD        +     +L+S +G     +
Sbjct: 1192 APGPCCGGVGAAAIAGIGGEKAGG--FAPYYGDEPMDFKINTDEIMTSLKSVNGQIESLI 1249

Query: 936  SGGGGR-GRGRRKRDSGHVSPGTFFDKYSAAPDSG 969
            S  G R    R  RD     P     +Y   P+ G
Sbjct: 1250 SPDGSRKNPARNCRDLKFCHPELKSGEYWVDPNQG 1284



 Score = 58.2 bits (139), Expect = 5e-08
 Identities = 87/348 (25%), Positives = 115/348 (33%), Gaps = 53/348 (15%)

Query: 829  STACQNMIAS---LGAPNLNVTFNK------------KNPPEGKRKLSQNETDGA-AVAG 872
            S  C ++I     L  PN  + F +              PP G+         G   + G
Sbjct: 59   SVLCDDIICDDQELDCPNPEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPG 118

Query: 873  NPGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDG 932
              G    PG   PG+PG  GP G   S    +GP N   Q D   +     +   +G  G
Sbjct: 119  RNGDPGIPG--QPGSPGSPGPPGICESCP--TGPQNYSPQYDSYDVKSGVAVGGLAGYPG 174

Query: 933  KPVSGGGGRGRGRRKRDSGHV-SPGTFFDKYSAAPDSGGAPGVS--PGQQQASGAAVGGS 989
                  G  G       SGH  SPG+    Y   P   G  G S  PG   A G +    
Sbjct: 175  P----AGPPGPPGPPGTSGHPGSPGS--PGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAG 228

Query: 990  SAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIG--SLDG--GAKSDSSSPNVGEFA 1045
              GE+     P E+ L  P   KG   + G  P + G    DG  G K ++ +P +    
Sbjct: 229  KDGESGRPGRPGERGLPGPPGIKGPAGIPGF-PGMKGHRGFDGRNGEKGETGAPGL---- 283

Query: 1046 SDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKA------P 1099
                      E+ +   +  P  +     +P   G P LP      G  G +       P
Sbjct: 284  --------KGENGLPGENGAPGPMGPRG-APGERGRPGLPGAAGARGNDGARGSDGQPGP 334

Query: 1100 PPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPP 1147
            P   G      S       G  G PG  G PG      P   +GA  P
Sbjct: 335  PGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGP 382



 Score = 54.3 bits (129), Expect = 8e-07
 Identities = 102/447 (22%), Positives = 141/447 (31%), Gaps = 62/447 (13%)

Query: 730  PPPPDFATSALGGQ-PGFPFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQ 788
            P PP   T    GQ P  P G  G    P   PG N  P   G  GS G  G  G     
Sbjct: 89   PQPPTAPTRPPNGQGPQGPKGDPG----PPGIPGRNGDPGIPGQPGSPGSPGPPGICESC 144

Query: 789  P----DFQPSQRTSASKLGAL--SLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAP 842
            P    ++ P   +   K G     L  +  P+      G                + G P
Sbjct: 145  PTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPP-------------GTSGHP 191

Query: 843  NLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSK 902
                +   + PP         E   A  +G PG         PGA GP GP+G      +
Sbjct: 192  GSPGSPGYQGPP--------GEPGQAGPSGPPGP--------PGAIGPSGPAGKDGESGR 235

Query: 903  ASGP-----PNPPAQGDGTSLSPNYTLESTSGNDGKPVSGG--GGRG-RGRRKRDSGHVS 954
               P     P PP       +     ++   G DG+    G  G  G +G       + +
Sbjct: 236  PGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGA 295

Query: 955  PGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGE--------TRGAP-TPHEKAL 1005
            PG    +   AP   G PG+ PG   A G      S G+        T G P +P  K  
Sbjct: 296  PGPMGPR--GAPGERGRPGL-PGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGE 352

Query: 1006 TSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSS--SS 1063
              P+   G+    G + +       GA+     P +      +     A          +
Sbjct: 353  VGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGA 412

Query: 1064 DNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGG 1123
              P     A+ +P + G    P +    GE GP+      G+  +  +       G  G 
Sbjct: 413  RGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGE 472

Query: 1124 PGHPGTPGLEQVRTPTSSSGAPPPDEI 1150
            PG  G PG    R      G   P+ I
Sbjct: 473  PGANGLPGAAGERGAPGFRGPAGPNGI 499



 Score = 44.3 bits (103), Expect = 8e-04
 Identities = 172/673 (25%), Positives = 211/673 (31%), Gaps = 157/673 (23%)

Query: 41   TGGPPGPVDPAMSALGEPPILGMNMEPYGFHARGHS----ELHAGGLQAQPVHGFFGGQQ 96
            TGGPPG         GEP   G    P     +G +    E    GL   P  G  GG  
Sbjct: 646  TGGPPGENGKP----GEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAP--GLRGGAG 699

Query: 97   PHHGHPGSHHPHQHHPHFGGNFGGPD--PGASCLHGGRLLGYGGAAGGLGSQPPFAEGYE 154
            P    PG        P  G    GP   PGA+   G  L G  G  GGLGS  P  +   
Sbjct: 700  P----PG--------PEGGKGAAGPPGPPGAAGTPG--LQGMPGERGGLGSPGPKGD--- 742

Query: 155  HMAESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDS 214
               E  GP + G   PG       +G      PA   P D+    A    G+    GS  
Sbjct: 743  -KGEPGGPGADGV--PGKDGPRGPTGPIGPPGPAG-QPGDKGEGGAPGLPGIAGPRGSPG 798

Query: 215  HSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAAGRQVPGGAFPGAS 274
               E       G        +PG AP  +       +  G+    A G +  GG  PG +
Sbjct: 799  ERGETGPPGPAG--------FPG-APGQN------GEPGGKGERGAPGEKGEGGP-PGVA 842

Query: 275  AMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSR 334
              P  +G  G            P  Q    ++    G     F GAR +P          
Sbjct: 843  GPPGGSGPAG-----------PPGPQGVKGERGSPGGPGAAGFPGARGLP---------- 881

Query: 335  HPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPR---PQQGEAGTPSG 391
                 PP     P    P   P +  PP P G      S   + P+    Q GE G+P  
Sbjct: 882  ----GPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGA 937

Query: 392  -------------------GLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHP 432
                               GL  G P +P            ++  S  P +  +   + P
Sbjct: 938  QGPPGAPGPLGIAGITGARGLA-GPPGMPGPRG--SPGPQGVKGESGKPGANGLSGERGP 994

Query: 433  PPQQAPNQRLQHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSM-HNGALDNHLSPSAY 491
            P  Q           P     A  P  D  G+ G D     +GS    G    + SP A 
Sbjct: 995  PGPQG---------LPGLAGTAGEPGRD--GNPGSDGLPGRDGSPGGKGDRGENGSPGA- 1042

Query: 492  PGLPGEFTPPVP--------DSFPSGP--PLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQ 541
            PG PG   PP P        D   SGP  P   P P                 +     Q
Sbjct: 1043 PGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGP--------------AGSRGAPGPQ 1088

Query: 542  QQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQP 601
              +  + +  +  A  IK         R    N    G PG  GQ G + G P  G A P
Sbjct: 1089 GPRGDKGETGERGAAGIK-------GHRGFPGNPGAPGSPGPAGQQGAI-GSP--GPAGP 1138

Query: 602  NFEREGGSTGAGRLGTFEQQAPHLAQESAWFSGPHPPPGDLLPRRMGGS-GLPADCGPHD 660
                 G S   G+ GT     P          GP  P G+   R   GS G P   GP  
Sbjct: 1139 R-GPVGPSGPPGKDGTSGHPGP---------IGPPGPRGNRGERGSEGSPGHPGQPGPPG 1188

Query: 661  PSLAPPPPPGGSG 673
            P  AP P  GG G
Sbjct: 1189 PPGAPGPCCGGVG 1201



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 109/404 (26%), Positives = 125/404 (30%), Gaps = 73/404 (18%)

Query: 9    PQVNSRNAGQGERNF-NETGLSMNTHFKAPAFHTGGPPGPVDP-AMSALGEPP----ILG 62
            P  N    G+GER    E G              GGPPG   P   S    PP    + G
Sbjct: 815  PGQNGEPGGKGERGAPGEKG-------------EGGPPGVAGPPGGSGPAGPPGPQGVKG 861

Query: 63   MNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHGHPGSHHPHQHHPHFGGNFGGP- 121
                P G  A G     A GL   P      G     G PG   P    P   GN G P 
Sbjct: 862  ERGSPGGPGAAGFPG--ARGLPGPPGSNGNPGPPGPSGSPGKDGP----PGPAGNTGAPG 915

Query: 122  DPGASCLHGGRLLGYGGAAGGLGSQ-PPFAEGYEHMAESQGPESFG--PQRPG--NLPDF 176
             PG S   G    G  G  G  G+Q PP A G   +A   G       P  PG    P  
Sbjct: 916  SPGVSGPKGDA--GQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGP 973

Query: 177  HSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSD-------SHSLEPRRVTNQGAVD 229
                  S    A  L  ++ P       GL  ++G         S  L  R  +  G  D
Sbjct: 974  QGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGD 1033

Query: 230  SLEYNYPGE-------APSGHFDMFSPSDSEGQ--------LPHYAAGRQVPGGAFP--- 271
              E   PG         P G       S   G+         P  A  R  PG   P   
Sbjct: 1034 RGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGD 1093

Query: 272  -GASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPS 330
             G +    AAG+ G    H   P   P     P    QQ  +     +G R  PVG    
Sbjct: 1094 KGETGERGAAGIKG----HRGFPGN-PGAPGSPGPAGQQGAIGSPGPAGPRG-PVGPSGP 1147

Query: 331  VGSRHPLMQPPQQAPPPPQ--------QQPPQQPPQQQPPPPPG 366
             G       P    PP P+        +  P  P Q  PP PPG
Sbjct: 1148 PGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPG 1191



 Score = 32.0 bits (71), Expect = 4.0
 Identities = 24/63 (38%), Positives = 25/63 (39%), Gaps = 10/63 (15%)

Query: 1091 AGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAP-PPDE 1149
            AG  GP  PP   G    S    +P S G  G PG PG  G          SG P PP  
Sbjct: 170  AGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAG---------PSGPPGPPGA 220

Query: 1150 IHP 1152
            I P
Sbjct: 221  IGP 223


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
            sapiens]
          Length = 1691

 Score =  105 bits (262), Expect = 3e-22
 Identities = 291/1236 (23%), Positives = 375/1236 (30%), Gaps = 285/1236 (23%)

Query: 94   GQQPHHGHPGSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLGSQPPFAEGY 153
            G++   G PG    H   P F G  G P P       G + G  G  G  G  PP   G+
Sbjct: 45   GEKGERGFPGLEG-HPGLPGFPGPEGPPGPRGQKGDDG-IPGPPGPKGIRG--PPGLPGF 100

Query: 154  EHMAESQG-PESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGS 212
                   G P   G   P  +P  + +        +P  P  Q P       G+    GS
Sbjct: 101  PGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGS 160

Query: 213  DSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAAGRQVPGGAF-- 270
               S  P    N G        YPG  P G   +  P+   G +     G   P G    
Sbjct: 161  IIMSSLPGPKGNPG--------YPG--PPGIQGLPGPTGIPGPI-----GPPGPPGLMGP 205

Query: 271  PGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQP----QQQQQQHGVFFERFSGARKMPVG 326
            PG   +P   G +GL+    +  + +   Q  P    Q  +Q+  +  E   G + +P  
Sbjct: 206  PGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLP-- 263

Query: 327  LEPSVGSRHPLMQPPQQAPPPP----------QQQP------------------------ 352
                 G R P   P  + PP P          Q +P                        
Sbjct: 264  -----GDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDP 318

Query: 353  --PQQPPQQQ---------PPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLP 401
              P +P +           PP PPGL++         PRP  G      G +  G P LP
Sbjct: 319  GYPGEPGRDGEKGQKGDTGPPGPPGLVI---------PRPGTGITIGEKGNI--GLPGLP 367

Query: 402  SQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDF 461
             +  +  +P   ++     P       M  P P   P +R Q  D  P       P    
Sbjct: 368  GEKGERGFP--GIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGP-------PGISI 418

Query: 462  PGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSFPSGPPLQHPAPDHQS 521
            PG  G+D                   P A PGLPG          P GP   H  P  + 
Sbjct: 419  PGPPGLDG-----------------QPGA-PGLPG----------PPGPAGPHIPPSDEI 450

Query: 522  LQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNL-AQLGH 580
             +            +  Q +Q  +  +       +         Q      P     LG 
Sbjct: 451  CEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGF 510

Query: 581  PGDVGQGGLVHG-------GPVGGLAQPNFEREGGSTG-----------AGRLGTFEQQA 622
            PG  G+ G           G  G    P F    G  G            G LG+    A
Sbjct: 511  PGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGS--PGA 568

Query: 623  PHL-------AQESA-WFSGPHPPPGDLL-------PRRMGGSGLPADCGPHDP-SLAPP 666
            P L        Q+      GP   PG +        P   G  GLP + GP  P    PP
Sbjct: 569  PGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPP 628

Query: 667  PPPGGSGVL----------FRGPLQEP---MRMPGEGHVPALPS----------PGLQFG 703
             P G  G+             GP  +P   +  PG+  +P  P           PGL   
Sbjct: 629  GPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQ 688

Query: 704  GSLGGL-GQLQSPGA-GVGLPSAASERR----PPPPDFATS----ALGGQPGFPFGAAGR 753
              L G+ G    PG  G+GLP     +     P PP    +     L G PG P G  G 
Sbjct: 689  PGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPP-GFPGP 747

Query: 754  QSTPHSG-PGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNK 812
            +  P    PG   PP   G  G+ G  G  G +P  P   P  RT    L     G    
Sbjct: 748  KGEPGFALPGPPGPPGLPGFKGALGPKGDRG-FPGPPG--PPGRTGLDGLPGPK-GDVG- 802

Query: 813  PSSKDNLFGQSCLAALST----ACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGA 868
            P+ +    G   L  +          +   +G P L+    +K  P            G 
Sbjct: 803  PNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPG---------PPGL 853

Query: 869  AVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKAS--------------GPPNPPAQGD 914
             V G PG    PG   PGAPGP GP G+     KA               GPP PP    
Sbjct: 854  DVPGPPGERGSPG--IPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLG 911

Query: 915  GTSLSPNYTLESTSGNDGKPVSGG-----GGRGRGRRKRDSGHVSPGTFFDK-YSAAPDS 968
                S    L+   G  G+P   G     G +G        G + P     K     P  
Sbjct: 912  IPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGL 971

Query: 969  GGAPGVS-----------PGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELL 1017
             G PGVS           PGQ   SG        G       P +  L  P   KG    
Sbjct: 972  PGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGT--- 1028

Query: 1018 LGDQ-------------PDLIGSLDG-----GAKSDSSSPNVGEFA--------SDEVST 1051
            +GD              P  +    G     G K D   P +             +    
Sbjct: 1029 IGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLP 1088

Query: 1052 SYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNS 1111
             Y     +  S  +P  L     +P   G P LP      G  G   PP   G+     +
Sbjct: 1089 GYPGNPGIKGSVGDP-GLPGLPGTPGAKGQPGLP------GFPGTPGPPGPKGISGPPGN 1141

Query: 1112 TSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPP 1147
               P   G  GG GHPG PG    +      G P P
Sbjct: 1142 PGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGP 1177



 Score = 98.2 bits (243), Expect = 5e-20
 Identities = 237/980 (24%), Positives = 297/980 (30%), Gaps = 190/980 (19%)

Query: 271  PGASAMPRAAGMVGLSKMHAQP-PQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEP 329
            PGA  +P   G  G   +   P P+ +P             G+ F+   G    P GL  
Sbjct: 566  PGAPGLPGLPGTPGQDGLPGLPGPKGEPG------------GITFKGERGPPGNP-GLPG 612

Query: 330  SVGSRHPLMQPPQQAPPPPQQQP--------PQQPPQQQPPPPPGLLVRQNSCPPALPRP 381
              G+  P M PP   PP P  +         P QP    P   PG  + Q   P     P
Sbjct: 613  LPGNIGP-MGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNP 671

Query: 382  -QQGEAGTPSG-GL--QDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQA 437
             + G+ G P   GL  Q G P +P    +   P   L      P  +    +  PP    
Sbjct: 672  GRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGP---PGPKGFPGIPGPPGAPG 728

Query: 438  PNQRLQHFDAPP----YMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPG 493
               R+   + PP    +      P F  PG  G      + G+         L P    G
Sbjct: 729  TPGRIG-LEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGA---------LGPKGDRG 778

Query: 494  LPGEFTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQN 553
             PG   PP P        L  P  D                                   
Sbjct: 779  FPG---PPGPPGRTGLDGLPGPKGD----------------------------------- 800

Query: 554  AALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGAG 613
                   +    Q   +  P L  +G  G  G  G+   GP+G         E G  G  
Sbjct: 801  -------VGPNGQPGPMGPPGLPGIGVQGPPGPPGIP--GPIGQPGLHGIPGEKGDPGPP 851

Query: 614  RLGTFEQQAPHLAQESAWFSGPHPPPGDL-LPRRMGGSGLPADCGPHDPSLAPPPPPGGS 672
             L          +       GP  PPG   LP + G SG P   G     + PP PPG  
Sbjct: 852  GLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMG-MMGPPGPPGPL 910

Query: 673  GVLFRGP---------------LQEPMRMPGEGHVPALPSP-GLQFGGSLGGLGQLQSPG 716
            G+  R                 L  P    G    P LP P G      LG  G+   PG
Sbjct: 911  GIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPG 970

Query: 717  AGVGLPSAASER--RPPPPDFATSALGGQPGFPFGAAGRQSTPH--SGPGVNSPPSAGGG 772
               G+P  +  +  +  P D     L GQPG P G  G +  P     PG+  PP   G 
Sbjct: 971  LP-GIPGVSGPKGYQGLPGDPGQPGLSGQPGLP-GPPGPKGNPGLPGQPGLIGPPGLKGT 1028

Query: 773  GGSSG--------GGGGGGAYPPQPDFQ--PSQRTSASKLGALSLGSFNKPSSKDNLFGQ 822
             G  G        G  G    P QP     P Q+      G  S+G    P  K    G+
Sbjct: 1029 IGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPK----GE 1084

Query: 823  SCLAAL--STACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGA-AVAGNPGSDYF 879
              L     +   +  +   G P L  T   K  P            G   ++G PG+   
Sbjct: 1085 PGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGL 1144

Query: 880  PG-------GTAPGAPGPGGPSGTSSS-------------GSKASGPPNPPAQGDGTSLS 919
            PG       G  PG PGP G  G                 G    G P PP     +   
Sbjct: 1145 PGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQK 1204

Query: 920  PNYTLESTSGNDGKPVSGG--GGRG-RGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVS- 975
             +  L    GN G P   G  G  G  G +       SPG   +     P   G PG   
Sbjct: 1205 GDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPG 1264

Query: 976  -------PGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGD--QPDLIG 1026
                   PG +   G    G   GE      P    L      +G   L G+  +P L  
Sbjct: 1265 PTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGL-- 1322

Query: 1027 SLDGGAKSDSSSPNVGEFASDE----VSTSYANEDEVSS-SSDNPQALVKASRSPLV--- 1078
                G K D   P V  F   +    V  S   E E        P  L   S   ++   
Sbjct: 1323 ---NGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKG 1379

Query: 1079 -TGSPKLP----------PRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHP 1127
              G P +P          P+G   G  GP  PP   G   +          G  G PG P
Sbjct: 1380 DAGPPGIPGQPGLKGLPGPQGP-QGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQP 1438

Query: 1128 GTPGLEQVRTPTSSSGAPPP 1147
            GT GL+    P    G P P
Sbjct: 1439 GTRGLDGPPGPDGLQGPPGP 1458



 Score = 87.8 bits (216), Expect = 6e-17
 Identities = 300/1234 (24%), Positives = 376/1234 (30%), Gaps = 230/1234 (18%)

Query: 43   GPPGPVD-PAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQP----VHGFFGGQQP 97
            GPPGP   P M   GEP  + M+  P      G+      G+Q  P    + G  G   P
Sbjct: 144  GPPGPPGIPGMK--GEPGSIIMSSLPGPKGNPGYPG--PPGIQGLPGPTGIPGPIGPPGP 199

Query: 98   HH--GHPGSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLGSQP-----PFA 150
                G PG         + G NF GP  G     G  L G  G  G +  Q       F 
Sbjct: 200  PGLMGPPGPPGLPGPKGNMGLNFQGPK-GEKGEQG--LQGPPGPPGQISEQKRPIDVEFQ 256

Query: 151  EGYEHMAESQGPESF-GPQRPGNLPDFHSSGASSHAVPAPC-LPLDQSPNRAASFHGLPS 208
            +G + +   +GP    G + P   P            P     P     N      GLP 
Sbjct: 257  KGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPG 316

Query: 209  SSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAAGRQVPG- 267
              G      EP R   +G             P G   +  P    G          +PG 
Sbjct: 317  DPGYPG---EPGRDGEKGQKGDT-------GPPGPPGLVIPRPGTGITIGEKGNIGLPGL 366

Query: 268  ------GAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGAR 321
                    FPG    P   G  G + M    P   P ++ Q +  +   G+      G  
Sbjct: 367  PGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQ-KGDEGPPGISIPGPPGLD 425

Query: 322  KMP--VGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQ------------------- 360
              P   GL    G   P + P  +   P    PP  P  +                    
Sbjct: 426  GQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCI 485

Query: 361  ------PPPPPGLLVRQNSCPPALPRP--------QQGEAGTPSGGLQDGGPMLPSQHAQ 406
                  PP  PGL        P LP P        Q+GE G        G P +P     
Sbjct: 486  GTGISGPPGQPGL--------PGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGA 537

Query: 407  FEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFD----FP 462
              +P  + E   +  +          P  +     L    AP    +   P  D     P
Sbjct: 538  PGFPGSKGEPGDILTF----------PGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLP 587

Query: 463  GSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSFPSGPPLQHPAPDHQSL 522
            G  G     ++ G    G   N       PGLPG   P  P  F  GPP        Q +
Sbjct: 588  GPKGEPGGITFKGE--RGPPGN----PGLPGLPGNIGPMGPPGF--GPPGPVGEKGIQGV 639

Query: 523  QQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQL-GHP 581
                 Q      +    Q   Q  +     N       +          QP L  + G  
Sbjct: 640  AGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPG-RDGDVGLPGDPGLPGQPGLPGIPGSK 698

Query: 582  GDVGQGGLVHGGPVGGLAQPNFEREGGSTGA-GRLGTFEQQAPHLAQESAWFSGPHPPPG 640
            G+ G  G+   GP G    P      G+ G  GR+G      P        F GP   PG
Sbjct: 699  GEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGP------PGFPGPKGEPG 752

Query: 641  DLLPRRMGGSGLPADCGPHDPS-----LAPPPPPGGSGVL-FRGPLQE--PMRMPGEGHV 692
              LP   G  GLP   G   P        PP PPG +G+    GP  +  P   PG    
Sbjct: 753  FALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGP 812

Query: 693  PALPSPGLQFGGSLGGL-GQLQSPGAGVGLPSAASERRPPPPDF-ATSALGGQPGFPFGA 750
            P LP  G+Q      G+ G +  PG   G+P    +  PP  D        G PG P GA
Sbjct: 813  PGLPGIGVQGPPGPPGIPGPIGQPGLH-GIPGEKGDPGPPGLDVPGPPGERGSPGIP-GA 870

Query: 751  AGRQSTPHSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSF 810
             G    P S PG+     A G  G+ G  G  G  PP P   P       + G   L   
Sbjct: 871  PGPIGPPGS-PGLPGKAGASGFPGTKGEMGMMG--PPGP---PGPLGIPGRSGVPGL--- 921

Query: 811  NKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAV 870
                  D L GQ  L   +        S G P L         P     +  N       
Sbjct: 922  ---KGDDGLQGQPGLPGPT----GEKGSKGEPGL---------PGPPGPMDPNLLGSKGE 965

Query: 871  AGNPGSDYFPGGTAP----GAPGPGGPSGTSSSGSKASGPP----NPPAQGDGTSLSPNY 922
             G PG    PG + P    G PG  G  G S       GPP    NP   G    + P  
Sbjct: 966  KGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPG-LPGPPGPKGNPGLPGQPGLIGPP- 1023

Query: 923  TLESTSGNDGKPVSGG--------------GGRGRGRRKRDSGHVSPGTFFDKYSAAPDS 968
             L+ T G+ G P   G              G  G   +K D G   PG         P  
Sbjct: 1024 GLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKG--DPGISSIGLPGLPGP 1081

Query: 969  GGAPGVS--PGQQQASGAAVGGSSAGETRGAP----------------TPHEKALTSPSW 1010
             G PG+   PG     G+ VG        G P                 P  K ++ P  
Sbjct: 1082 KGEPGLPGYPGNPGIKGS-VGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPG 1140

Query: 1011 GKGAELLLGDQPDLIGSLDGGAKSDSSSPNV-GEFASDEVSTSYANEDEVSS---SSDNP 1066
              G    L  +P  +G   GG       P   G+   D +      + E       +  P
Sbjct: 1141 NPG----LPGEPGPVGG--GGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGP 1194

Query: 1067 QALVKASRS------PLVTGSPKLP-PRGVGA-----GEHGPKAPPPALGLGIMSNSTST 1114
              L   S        P + G+P LP P+G        G  GP  PP + G          
Sbjct: 1195 PGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPG---------- 1244

Query: 1115 PDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPPD 1148
            P   G  G PG  G PG      PT   G P P+
Sbjct: 1245 PALEGPKGNPGPQGPPGRPG---PTGFQGLPGPE 1275



 Score = 76.6 bits (187), Expect = 1e-13
 Identities = 154/597 (25%), Positives = 197/597 (32%), Gaps = 122/597 (20%)

Query: 579  GHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGAGRLGTFEQQAPHLAQESAWFSGPHPP 638
            G PG  G  GL   GP G    P  + E GS     L   +    +          P PP
Sbjct: 132  GFPGSPGFPGLQ--GPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGY----------PGPP 179

Query: 639  PGDLLPRRMGGSGLPADCGPHDPS--LAPPPPPG------GSGVLFRGPLQEPMRMPGEG 690
                LP   G +G+P   GP  P   + PP PPG        G+ F+GP  E     GE 
Sbjct: 180  GIQGLP---GPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEK----GEQ 232

Query: 691  HVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALGGQPGFPFGA 750
             +   P P  Q       +  ++      GLP    +R PP P      + G PG P G 
Sbjct: 233  GLQGPPGPPGQISEQKRPI-DVEFQKGDQGLPG---DRGPPGPP----GIRGPPGPPGGE 284

Query: 751  AGRQSTPHSGPGVNSPPSAGGGGGSSGGGG--GGGAYPPQP--DFQPSQRTSASKLGALS 806
             G +      PG    P   G  G  G  G  G   YP +P  D +  Q+      G   
Sbjct: 285  KGEKGE-QGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPG 343

Query: 807  LGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETD 866
            L    +P +   + G+               ++G P L     ++  P  +         
Sbjct: 344  L-VIPRPGTGITI-GEK-------------GNIGLPGLPGEKGERGFPGIQGPPGLPGPP 388

Query: 867  GAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSK-------ASGPPNPPAQGDGTSLS 919
            GAAV G PG   FPG    G  G  GP G S  G         A G P PP    G  + 
Sbjct: 389  GAAVMGPPGPPGFPGER--GQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPA-GPHIP 445

Query: 920  PNYTLESTSGNDGKPVSGG--GGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPG 977
            P+  +    G  G P S G  G +G    K D G           S  P   G PG+ PG
Sbjct: 446  PSDEI-CEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGL-PG 503

Query: 978  QQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGD--QPDLIGSLDG--GAK 1033
               + G        G+  GA  P  K L       GA    G   +P  I +  G  G K
Sbjct: 504  PPGSLGFPGQKGEKGQA-GATGP--KGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDK 560

Query: 1034 SDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGE 1093
             +  SP                                   +P + G P  P +    G 
Sbjct: 561  GELGSPG----------------------------------APGLPGLPGTPGQDGLPGL 586

Query: 1094 HGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPPDEI 1150
             GPK  P  +               G  G PG+PG PGL     P    G  PP  +
Sbjct: 587  PGPKGEPGGITFK------------GERGPPGNPGLPGLPGNIGPMGPPGFGPPGPV 631



 Score = 50.8 bits (120), Expect = 8e-06
 Identities = 90/364 (24%), Positives = 122/364 (33%), Gaps = 69/364 (18%)

Query: 863  NETDGAAVAGNPGSDYFPGGTA----PGAPGPGGPSGTSSSGSKAS----GPPNP----- 909
            ++ D + + G  G   FPG       PG PGP GP G    G K      GPP P     
Sbjct: 36   SKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPR--GQKGDDGIPGPPGPKGIRG 93

Query: 910  PAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSG 969
            P    G   +P   L    G+DG P   G     G +       SPG  F      P   
Sbjct: 94   PPGLPGFPGTPG--LPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPG--FPGLQGPP--- 146

Query: 970  GAPGVSPGQQQASGAAVGGSSAGETRGAP----------TPHEKALTSPSWGKGAELLLG 1019
            G PG+ PG +   G+ +  S  G  +G P           P    +  P    G   L+G
Sbjct: 147  GPPGI-PGMKGEPGSIIMSSLPGP-KGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMG 204

Query: 1020 DQ--PDLIGSLDG------GAKSDSSSPNV-------GEFASDE--VSTSYANEDEVSSS 1062
                P L G          G K +     +       G+ +  +  +   +   D+    
Sbjct: 205  PPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPG 264

Query: 1063 SDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGG 1122
               P         P + G P   P G   GE G +  P   G          P   G  G
Sbjct: 265  DRGPPG------PPGIRGPPG--PPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPG 316

Query: 1123 GPGHPGTPGLEQVRTPTSSSGAPPPDEIHPLEILQAQIQLQRQQFSISEDQPLGLKG--G 1180
             PG+PG PG +  +     +G P P  +         I       +I E   +GL G  G
Sbjct: 317  DPGYPGEPGRDGEKGQKGDTGPPGPPGL--------VIPRPGTGITIGEKGNIGLPGLPG 368

Query: 1181 KKGE 1184
            +KGE
Sbjct: 369  EKGE 372



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 162/657 (24%), Positives = 198/657 (30%), Gaps = 167/657 (25%)

Query: 43   GPPGPVDPAM----SALGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPH 98
            GPPGP+DP +       GEP + G+   P     +G+      GL   P      GQ   
Sbjct: 950  GPPGPMDPNLLGSKGEKGEPGLPGI---PGVSGPKGYQ-----GLPGDP------GQPGL 995

Query: 99   HGHPGSHHPHQHHPHFGGNFGGP-DPGASCLHGGRLLGYGGAAGGLGSQP-PFAEGYEHM 156
             G PG   P    P   GN G P  PG        L+G  G  G +G    P  +G E  
Sbjct: 996  SGQPGLPGP----PGPKGNPGLPGQPG--------LIGPPGLKGTIGDMGFPGPQGVEGP 1043

Query: 157  AESQGP--ESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDS 214
                G   +   P  PG   D    G SS  +P   LP  +       + G P   GS  
Sbjct: 1044 PGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPG--LPGPKGEPGLPGYPGNPGIKGSVG 1101

Query: 215  HSLEPRRVTNQGAVDSLEY-NYPGE-APSGHFDMFSPSDSEGQL--PHYAAGRQVPGGAF 270
                P      GA        +PG   P G   +  P  + G    P    G   PG   
Sbjct: 1102 DPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPG 1161

Query: 271  P-GASAMPRAAGMVGLSKMHAQPPQQ---QPQQQQQPQQQQQQHGVFFERFSGARKMPVG 326
            P G    P   G+ G +    +P Q     P     P    Q+         G   +P  
Sbjct: 1162 PPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGP 1221

Query: 327  L-EPSVGSRHPLMQPPQQ--APPPPQQQPPQQPPQQQPPPPPGLLVRQN----SCPPALP 379
              EP       +  PP    +P P  + P   P  Q PP  PG    Q       PP LP
Sbjct: 1222 KGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLP 1281

Query: 380  RPQ--QGEAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQA 437
                 +GE G P    Q G P LP                            Q PP  Q 
Sbjct: 1282 GNGGIKGEKGNPG---QPGLPGLPGLKGD-----------------------QGPPGLQG 1315

Query: 438  PNQRLQHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGE 497
               R       P +N  K       G  G+     + G      +     P   PGL G 
Sbjct: 1316 NPGR-------PGLNGMK-------GDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIG- 1360

Query: 498  FTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALM 557
                     P GPP   P P  QS+  +          Q                     
Sbjct: 1361 ---------PPGPP-GLPGPSGQSIIIKGDAGPPGIPGQPG------------------- 1391

Query: 558  IKQMASRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGAGRLGT 617
            +K +      Q L  P     G PGD G+ GL           P F+  GG  G      
Sbjct: 1392 LKGLPGPQGPQGLPGPT----GPPGDPGRNGL-----------PGFDGAGGRKG------ 1430

Query: 618  FEQQAPHLAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGSGV 674
                                 PG  LP + G  GL    GP D    PP PPG S V
Sbjct: 1431 --------------------DPG--LPGQPGTRGLDGPPGP-DGLQGPPGPPGTSSV 1464


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
            sapiens]
          Length = 1685

 Score =  105 bits (262), Expect = 3e-22
 Identities = 291/1236 (23%), Positives = 375/1236 (30%), Gaps = 285/1236 (23%)

Query: 94   GQQPHHGHPGSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLGSQPPFAEGY 153
            G++   G PG    H   P F G  G P P       G + G  G  G  G  PP   G+
Sbjct: 45   GEKGERGFPGLEG-HPGLPGFPGPEGPPGPRGQKGDDG-IPGPPGPKGIRG--PPGLPGF 100

Query: 154  EHMAESQG-PESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGS 212
                   G P   G   P  +P  + +        +P  P  Q P       G+    GS
Sbjct: 101  PGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGS 160

Query: 213  DSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAAGRQVPGGAF-- 270
               S  P    N G        YPG  P G   +  P+   G +     G   P G    
Sbjct: 161  IIMSSLPGPKGNPG--------YPG--PPGIQGLPGPTGIPGPI-----GPPGPPGLMGP 205

Query: 271  PGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQP----QQQQQQHGVFFERFSGARKMPVG 326
            PG   +P   G +GL+    +  + +   Q  P    Q  +Q+  +  E   G + +P  
Sbjct: 206  PGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLP-- 263

Query: 327  LEPSVGSRHPLMQPPQQAPPPP----------QQQP------------------------ 352
                 G R P   P  + PP P          Q +P                        
Sbjct: 264  -----GDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDP 318

Query: 353  --PQQPPQQQ---------PPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLP 401
              P +P +           PP PPGL++         PRP  G      G +  G P LP
Sbjct: 319  GYPGEPGRDGEKGQKGDTGPPGPPGLVI---------PRPGTGITIGEKGNI--GLPGLP 367

Query: 402  SQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDF 461
             +  +  +P   ++     P       M  P P   P +R Q  D  P       P    
Sbjct: 368  GEKGERGFP--GIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGP-------PGISI 418

Query: 462  PGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSFPSGPPLQHPAPDHQS 521
            PG  G+D                   P A PGLPG          P GP   H  P  + 
Sbjct: 419  PGPPGLDG-----------------QPGA-PGLPG----------PPGPAGPHIPPSDEI 450

Query: 522  LQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNL-AQLGH 580
             +            +  Q +Q  +  +       +         Q      P     LG 
Sbjct: 451  CEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGF 510

Query: 581  PGDVGQGGLVHG-------GPVGGLAQPNFEREGGSTG-----------AGRLGTFEQQA 622
            PG  G+ G           G  G    P F    G  G            G LG+    A
Sbjct: 511  PGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGS--PGA 568

Query: 623  PHL-------AQESA-WFSGPHPPPGDLL-------PRRMGGSGLPADCGPHDP-SLAPP 666
            P L        Q+      GP   PG +        P   G  GLP + GP  P    PP
Sbjct: 569  PGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPP 628

Query: 667  PPPGGSGVL----------FRGPLQEP---MRMPGEGHVPALPS----------PGLQFG 703
             P G  G+             GP  +P   +  PG+  +P  P           PGL   
Sbjct: 629  GPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQ 688

Query: 704  GSLGGL-GQLQSPGA-GVGLPSAASERR----PPPPDFATS----ALGGQPGFPFGAAGR 753
              L G+ G    PG  G+GLP     +     P PP    +     L G PG P G  G 
Sbjct: 689  PGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPP-GFPGP 747

Query: 754  QSTPHSG-PGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNK 812
            +  P    PG   PP   G  G+ G  G  G +P  P   P  RT    L     G    
Sbjct: 748  KGEPGFALPGPPGPPGLPGFKGALGPKGDRG-FPGPPG--PPGRTGLDGLPGPK-GDVG- 802

Query: 813  PSSKDNLFGQSCLAALST----ACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGA 868
            P+ +    G   L  +          +   +G P L+    +K  P            G 
Sbjct: 803  PNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPG---------PPGL 853

Query: 869  AVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKAS--------------GPPNPPAQGD 914
             V G PG    PG   PGAPGP GP G+     KA               GPP PP    
Sbjct: 854  DVPGPPGERGSPG--IPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLG 911

Query: 915  GTSLSPNYTLESTSGNDGKPVSGG-----GGRGRGRRKRDSGHVSPGTFFDK-YSAAPDS 968
                S    L+   G  G+P   G     G +G        G + P     K     P  
Sbjct: 912  IPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGL 971

Query: 969  GGAPGVS-----------PGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELL 1017
             G PGVS           PGQ   SG        G       P +  L  P   KG    
Sbjct: 972  PGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGT--- 1028

Query: 1018 LGDQ-------------PDLIGSLDG-----GAKSDSSSPNVGEFA--------SDEVST 1051
            +GD              P  +    G     G K D   P +             +    
Sbjct: 1029 IGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLP 1088

Query: 1052 SYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNS 1111
             Y     +  S  +P  L     +P   G P LP      G  G   PP   G+     +
Sbjct: 1089 GYPGNPGIKGSVGDP-GLPGLPGTPGAKGQPGLP------GFPGTPGPPGPKGISGPPGN 1141

Query: 1112 TSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPP 1147
               P   G  GG GHPG PG    +      G P P
Sbjct: 1142 PGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGP 1177



 Score =  100 bits (249), Expect = 9e-21
 Identities = 237/974 (24%), Positives = 297/974 (30%), Gaps = 184/974 (18%)

Query: 271  PGASAMPRAAGMVGLSKMHAQP-PQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEP 329
            PGA  +P   G  G   +   P P+ +P             G+ F+   G    P GL  
Sbjct: 566  PGAPGLPGLPGTPGQDGLPGLPGPKGEPG------------GITFKGERGPPGNP-GLPG 612

Query: 330  SVGSRHPLMQPPQQAPPPPQQQP--------PQQPPQQQPPPPPGLLVRQNSCPPALPRP 381
              G+  P M PP   PP P  +         P QP    P   PG  + Q   P     P
Sbjct: 613  LPGNIGP-MGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNP 671

Query: 382  -QQGEAGTPSG-GL--QDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQA 437
             + G+ G P   GL  Q G P +P    +   P   L      P  +    +  PP    
Sbjct: 672  GRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGP---PGPKGFPGIPGPPGAPG 728

Query: 438  PNQRLQHFDAPP----YMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPG 493
               R+   + PP    +      P F  PG  G      + G+         L P    G
Sbjct: 729  TPGRIG-LEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGA---------LGPKGDRG 778

Query: 494  LPGEFTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQN 553
             PG   PP P        L  P  D                                   
Sbjct: 779  FPG---PPGPPGRTGLDGLPGPKGD----------------------------------- 800

Query: 554  AALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGAG 613
                   +    Q   +  P L  +G  G  G  G+   GP+G         E G  G  
Sbjct: 801  -------VGPNGQPGPMGPPGLPGIGVQGPPGPPGIP--GPIGQPGLHGIPGEKGDPGPP 851

Query: 614  RLGTFEQQAPHLAQESAWFSGPHPPPGDL-LPRRMGGSGLPADCGPHDPSLAPPPPPGGS 672
             L          +       GP  PPG   LP + G SG P   G     + PP PPG  
Sbjct: 852  GLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMG-MMGPPGPPGPL 910

Query: 673  GVLFRGP---------------LQEPMRMPGEGHVPALPSP-GLQFGGSLGGLGQLQSPG 716
            G+  R                 L  P    G    P LP P G      LG  G+   PG
Sbjct: 911  GIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPG 970

Query: 717  AGVGLPSAASER--RPPPPDFATSALGGQPGFPFGAAGRQSTPH--SGPGVNSPPSAGGG 772
               G+P  +  +  +  P D     L GQPG P G  G +  P     PG+  PP   G 
Sbjct: 971  LP-GIPGVSGPKGYQGLPGDPGQPGLSGQPGLP-GPPGPKGNPGLPGQPGLIGPPGLKGT 1028

Query: 773  GGSSG--------GGGGGGAYPPQPDFQ--PSQRTSASKLGALSLGSFNKPSSKDNLFGQ 822
             G  G        G  G    P QP     P Q+      G  S+G    P  K    G+
Sbjct: 1029 IGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPK----GE 1084

Query: 823  SCLAAL--STACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGA-AVAGNPGSDYF 879
              L     +   +  +   G P L  T   K  P            G   ++G PG+   
Sbjct: 1085 PGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGL 1144

Query: 880  PG-------GTAPGAPGPGGPSGTSSS-------------GSKASGPPNPPAQGDGTSLS 919
            PG       G  PG PGP G  G                 G    G P PP     +   
Sbjct: 1145 PGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQK 1204

Query: 920  PNYTLESTSGNDGKPVSGG--GGRG-RGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVS- 975
             +  L    GN G P   G  G  G  G +       SPG   +     P   G PG   
Sbjct: 1205 GDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPG 1264

Query: 976  -PGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGD--QPDLIGSLDGGA 1032
             PG +   G    G   GE      P    L      +G   L G+  +P L      G 
Sbjct: 1265 LPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGL-----NGM 1319

Query: 1033 KSDSSSPNVGEFASDE----VSTSYANEDEVSS-SSDNPQALVKASRSPLV----TGSPK 1083
            K D   P V  F   +    V  S   E E        P  L   S   ++     G P 
Sbjct: 1320 KGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPG 1379

Query: 1084 LP----------PRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLE 1133
            +P          P+G   G  GP  PP   G   +          G  G PG PGT GL+
Sbjct: 1380 IPGQPGLKGLPGPQGP-QGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLD 1438

Query: 1134 QVRTPTSSSGAPPP 1147
                P    G P P
Sbjct: 1439 GPPGPDGLQGPPGP 1452



 Score = 76.6 bits (187), Expect = 1e-13
 Identities = 154/597 (25%), Positives = 197/597 (32%), Gaps = 122/597 (20%)

Query: 579  GHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGAGRLGTFEQQAPHLAQESAWFSGPHPP 638
            G PG  G  GL   GP G    P  + E GS     L   +    +          P PP
Sbjct: 132  GFPGSPGFPGLQ--GPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGY----------PGPP 179

Query: 639  PGDLLPRRMGGSGLPADCGPHDPS--LAPPPPPG------GSGVLFRGPLQEPMRMPGEG 690
                LP   G +G+P   GP  P   + PP PPG        G+ F+GP  E     GE 
Sbjct: 180  GIQGLP---GPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEK----GEQ 232

Query: 691  HVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALGGQPGFPFGA 750
             +   P P  Q       +  ++      GLP    +R PP P      + G PG P G 
Sbjct: 233  GLQGPPGPPGQISEQKRPI-DVEFQKGDQGLPG---DRGPPGPP----GIRGPPGPPGGE 284

Query: 751  AGRQSTPHSGPGVNSPPSAGGGGGSSGGGG--GGGAYPPQP--DFQPSQRTSASKLGALS 806
             G +      PG    P   G  G  G  G  G   YP +P  D +  Q+      G   
Sbjct: 285  KGEKGE-QGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPG 343

Query: 807  LGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETD 866
            L    +P +   + G+               ++G P L     ++  P  +         
Sbjct: 344  L-VIPRPGTGITI-GEK-------------GNIGLPGLPGEKGERGFPGIQGPPGLPGPP 388

Query: 867  GAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSK-------ASGPPNPPAQGDGTSLS 919
            GAAV G PG   FPG    G  G  GP G S  G         A G P PP    G  + 
Sbjct: 389  GAAVMGPPGPPGFPGER--GQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPA-GPHIP 445

Query: 920  PNYTLESTSGNDGKPVSGG--GGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPG 977
            P+  +    G  G P S G  G +G    K D G           S  P   G PG+ PG
Sbjct: 446  PSDEI-CEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGL-PG 503

Query: 978  QQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGD--QPDLIGSLDG--GAK 1033
               + G        G+  GA  P  K L       GA    G   +P  I +  G  G K
Sbjct: 504  PPGSLGFPGQKGEKGQA-GATGP--KGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDK 560

Query: 1034 SDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGE 1093
             +  SP                                   +P + G P  P +    G 
Sbjct: 561  GELGSPG----------------------------------APGLPGLPGTPGQDGLPGL 586

Query: 1094 HGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPPDEI 1150
             GPK  P  +               G  G PG+PG PGL     P    G  PP  +
Sbjct: 587  PGPKGEPGGITFK------------GERGPPGNPGLPGLPGNIGPMGPPGFGPPGPV 631



 Score = 50.8 bits (120), Expect = 8e-06
 Identities = 90/364 (24%), Positives = 122/364 (33%), Gaps = 69/364 (18%)

Query: 863  NETDGAAVAGNPGSDYFPGGTA----PGAPGPGGPSGTSSSGSKAS----GPPNP----- 909
            ++ D + + G  G   FPG       PG PGP GP G    G K      GPP P     
Sbjct: 36   SKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPR--GQKGDDGIPGPPGPKGIRG 93

Query: 910  PAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSG 969
            P    G   +P   L    G+DG P   G     G +       SPG  F      P   
Sbjct: 94   PPGLPGFPGTPG--LPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPG--FPGLQGPP--- 146

Query: 970  GAPGVSPGQQQASGAAVGGSSAGETRGAP----------TPHEKALTSPSWGKGAELLLG 1019
            G PG+ PG +   G+ +  S  G  +G P           P    +  P    G   L+G
Sbjct: 147  GPPGI-PGMKGEPGSIIMSSLPGP-KGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMG 204

Query: 1020 DQ--PDLIGSLDG------GAKSDSSSPNV-------GEFASDE--VSTSYANEDEVSSS 1062
                P L G          G K +     +       G+ +  +  +   +   D+    
Sbjct: 205  PPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPG 264

Query: 1063 SDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGG 1122
               P         P + G P   P G   GE G +  P   G          P   G  G
Sbjct: 265  DRGPPG------PPGIRGPPG--PPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPG 316

Query: 1123 GPGHPGTPGLEQVRTPTSSSGAPPPDEIHPLEILQAQIQLQRQQFSISEDQPLGLKG--G 1180
             PG+PG PG +  +     +G P P  +         I       +I E   +GL G  G
Sbjct: 317  DPGYPGEPGRDGEKGQKGDTGPPGPPGL--------VIPRPGTGITIGEKGNIGLPGLPG 368

Query: 1181 KKGE 1184
            +KGE
Sbjct: 369  EKGE 372



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 162/653 (24%), Positives = 199/653 (30%), Gaps = 165/653 (25%)

Query: 43   GPPGPVDPAM----SALGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPH 98
            GPPGP+DP +       GEP + G+   P     +G+      GL   P      GQ   
Sbjct: 950  GPPGPMDPNLLGSKGEKGEPGLPGI---PGVSGPKGYQ-----GLPGDP------GQPGL 995

Query: 99   HGHPGSHHPHQHHPHFGGNFGGP-DPGASCLHGGRLLGYGGAAGGLGSQP-PFAEGYEHM 156
             G PG   P    P   GN G P  PG        L+G  G  G +G    P  +G E  
Sbjct: 996  SGQPGLPGP----PGPKGNPGLPGQPG--------LIGPPGLKGTIGDMGFPGPQGVEGP 1043

Query: 157  AESQGP--ESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDS 214
                G   +   P  PG   D    G SS  +P   LP  +       + G P   GS  
Sbjct: 1044 PGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPG--LPGPKGEPGLPGYPGNPGIKGSVG 1101

Query: 215  HSLEPRRVTNQGAVDSLEY-NYPGE-APSGHFDMFSPSDSEGQL--PHYAAGRQVPGGAF 270
                P      GA        +PG   P G   +  P  + G    P    G   PG   
Sbjct: 1102 DPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPG 1161

Query: 271  P-GASAMPRAAGMVGLSKMHAQPPQQ---QPQQQQQPQQQQQQHGVFFERFSGARKMPVG 326
            P G    P   G+ G +    +P Q     P     P    Q+         G   +P  
Sbjct: 1162 PPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGP 1221

Query: 327  L-EPSVGSRHPLMQPPQQ--APPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQ- 382
              EP       +  PP    +P P  + P   P  Q PP  PGL   +   PP LP    
Sbjct: 1222 KGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEG--PPGLPGNGG 1279

Query: 383  -QGEAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQR 441
             +GE G P    Q G P LP                            Q PP  Q    R
Sbjct: 1280 IKGEKGNPG---QPGLPGLPGLKGD-----------------------QGPPGLQGNPGR 1313

Query: 442  LQHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPP 501
                   P +N  K       G  G+     + G      +     P   PGL G     
Sbjct: 1314 -------PGLNGMK-------GDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIG----- 1354

Query: 502  VPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQM 561
                 P GPP   P P  QS+  +          Q                     +K +
Sbjct: 1355 -----PPGPP-GLPGPSGQSIIIKGDAGPPGIPGQPG-------------------LKGL 1389

Query: 562  ASRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGAGRLGTFEQQ 621
                  Q L  P     G PGD G+ GL           P F+  GG  G          
Sbjct: 1390 PGPQGPQGLPGPT----GPPGDPGRNGL-----------PGFDGAGGRKG---------- 1424

Query: 622  APHLAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGSGV 674
                             PG  LP + G  GL    GP D    PP PPG S V
Sbjct: 1425 ----------------DPG--LPGQPGTRGLDGPPGP-DGLQGPPGPPGTSSV 1458



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 115/472 (24%), Positives = 145/472 (30%), Gaps = 97/472 (20%)

Query: 43   GPPGPVDPAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHGHP 102
            GPPGP  P +   G   + G+  +               GLQ QP      G++   G P
Sbjct: 902  GPPGPPGP-LGIPGRSGVPGLKGDD--------------GLQGQPGLPGPTGEKGSKGEP 946

Query: 103  G-SHHPHQHHPHFGGNFGGPD----PGASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHMA 157
            G    P    P+  G+ G       PG   + G +  GY G  G  G   P   G   + 
Sbjct: 947  GLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPK--GYQGLPGDPGQ--PGLSGQPGLP 1002

Query: 158  ESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDSHSL 217
               GP+   P  PG  P           +     P  Q         G+P   GS     
Sbjct: 1003 GPPGPKG-NPGLPGQ-PGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGL-- 1058

Query: 218  EPRRVTNQGAVDSLEYNYPG-EAPSGHFDMFSPSDSEGQLPHYAAGRQVPGGA----FPG 272
             P +  ++G         PG   P G          E  LP Y     + G       PG
Sbjct: 1059 -PGQKGDKGDPGISSIGLPGLPGPKG----------EPGLPGYPGNPGIKGSVGDPGLPG 1107

Query: 273  ASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVG 332
                P A G  GL      P    P+    P               G   +P    P  G
Sbjct: 1108 LPGTPGAKGQPGLPGFPGTPGPPGPKGISGPP--------------GNPGLPGEPGPVGG 1153

Query: 333  SRHPLMQ-PPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALP--RPQQGEAGTP 389
              HP    PP +   P Q   P    Q+  P  PG     N  PP LP    Q+G+ G P
Sbjct: 1154 GGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGF---GNPGPPGLPGLSGQKGDGGLP 1210

Query: 390  SGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVF----SMQHPP-PQQAPNQRLQH 444
                  G P LP                   P  EP F     +Q PP P  +P   L+ 
Sbjct: 1211 G---IPGNPGLPG------------------PKGEPGFHGFPGVQGPPGPPGSPGPALE- 1248

Query: 445  FDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPG 496
               P      + P    PG  G+       G   NG +         PGLPG
Sbjct: 1249 --GPKGNPGPQGP----PGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPG 1294


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
            sapiens]
          Length = 1688

 Score =  105 bits (262), Expect = 3e-22
 Identities = 291/1236 (23%), Positives = 375/1236 (30%), Gaps = 285/1236 (23%)

Query: 94   GQQPHHGHPGSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLGSQPPFAEGY 153
            G++   G PG    H   P F G  G P P       G + G  G  G  G  PP   G+
Sbjct: 45   GEKGERGFPGLEG-HPGLPGFPGPEGPPGPRGQKGDDG-IPGPPGPKGIRG--PPGLPGF 100

Query: 154  EHMAESQG-PESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGS 212
                   G P   G   P  +P  + +        +P  P  Q P       G+    GS
Sbjct: 101  PGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGS 160

Query: 213  DSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAAGRQVPGGAF-- 270
               S  P    N G        YPG  P G   +  P+   G +     G   P G    
Sbjct: 161  IIMSSLPGPKGNPG--------YPG--PPGIQGLPGPTGIPGPI-----GPPGPPGLMGP 205

Query: 271  PGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQP----QQQQQQHGVFFERFSGARKMPVG 326
            PG   +P   G +GL+    +  + +   Q  P    Q  +Q+  +  E   G + +P  
Sbjct: 206  PGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLP-- 263

Query: 327  LEPSVGSRHPLMQPPQQAPPPP----------QQQP------------------------ 352
                 G R P   P  + PP P          Q +P                        
Sbjct: 264  -----GDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDP 318

Query: 353  --PQQPPQQQ---------PPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLP 401
              P +P +           PP PPGL++         PRP  G      G +  G P LP
Sbjct: 319  GYPGEPGRDGEKGQKGDTGPPGPPGLVI---------PRPGTGITIGEKGNI--GLPGLP 367

Query: 402  SQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDF 461
             +  +  +P   ++     P       M  P P   P +R Q  D  P       P    
Sbjct: 368  GEKGERGFP--GIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGP-------PGISI 418

Query: 462  PGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSFPSGPPLQHPAPDHQS 521
            PG  G+D                   P A PGLPG          P GP   H  P  + 
Sbjct: 419  PGPPGLDG-----------------QPGA-PGLPG----------PPGPAGPHIPPSDEI 450

Query: 522  LQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNL-AQLGH 580
             +            +  Q +Q  +  +       +         Q      P     LG 
Sbjct: 451  CEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGF 510

Query: 581  PGDVGQGGLVHG-------GPVGGLAQPNFEREGGSTG-----------AGRLGTFEQQA 622
            PG  G+ G           G  G    P F    G  G            G LG+    A
Sbjct: 511  PGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGS--PGA 568

Query: 623  PHL-------AQESA-WFSGPHPPPGDLL-------PRRMGGSGLPADCGPHDP-SLAPP 666
            P L        Q+      GP   PG +        P   G  GLP + GP  P    PP
Sbjct: 569  PGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPP 628

Query: 667  PPPGGSGVL----------FRGPLQEP---MRMPGEGHVPALPS----------PGLQFG 703
             P G  G+             GP  +P   +  PG+  +P  P           PGL   
Sbjct: 629  GPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQ 688

Query: 704  GSLGGL-GQLQSPGA-GVGLPSAASERR----PPPPDFATS----ALGGQPGFPFGAAGR 753
              L G+ G    PG  G+GLP     +     P PP    +     L G PG P G  G 
Sbjct: 689  PGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPP-GFPGP 747

Query: 754  QSTPHSG-PGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNK 812
            +  P    PG   PP   G  G+ G  G  G +P  P   P  RT    L     G    
Sbjct: 748  KGEPGFALPGPPGPPGLPGFKGALGPKGDRG-FPGPPG--PPGRTGLDGLPGPK-GDVG- 802

Query: 813  PSSKDNLFGQSCLAALST----ACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGA 868
            P+ +    G   L  +          +   +G P L+    +K  P            G 
Sbjct: 803  PNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPG---------PPGL 853

Query: 869  AVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKAS--------------GPPNPPAQGD 914
             V G PG    PG   PGAPGP GP G+     KA               GPP PP    
Sbjct: 854  DVPGPPGERGSPG--IPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLG 911

Query: 915  GTSLSPNYTLESTSGNDGKPVSGG-----GGRGRGRRKRDSGHVSPGTFFDK-YSAAPDS 968
                S    L+   G  G+P   G     G +G        G + P     K     P  
Sbjct: 912  IPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGL 971

Query: 969  GGAPGVS-----------PGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELL 1017
             G PGVS           PGQ   SG        G       P +  L  P   KG    
Sbjct: 972  PGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGT--- 1028

Query: 1018 LGDQ-------------PDLIGSLDG-----GAKSDSSSPNVGEFA--------SDEVST 1051
            +GD              P  +    G     G K D   P +             +    
Sbjct: 1029 IGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLP 1088

Query: 1052 SYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNS 1111
             Y     +  S  +P  L     +P   G P LP      G  G   PP   G+     +
Sbjct: 1089 GYPGNPGIKGSVGDP-GLPGLPGTPGAKGQPGLP------GFPGTPGPPGPKGISGPPGN 1141

Query: 1112 TSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPP 1147
               P   G  GG GHPG PG    +      G P P
Sbjct: 1142 PGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGP 1177



 Score = 99.4 bits (246), Expect = 2e-20
 Identities = 237/977 (24%), Positives = 297/977 (30%), Gaps = 187/977 (19%)

Query: 271  PGASAMPRAAGMVGLSKMHAQP-PQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEP 329
            PGA  +P   G  G   +   P P+ +P             G+ F+   G    P GL  
Sbjct: 566  PGAPGLPGLPGTPGQDGLPGLPGPKGEPG------------GITFKGERGPPGNP-GLPG 612

Query: 330  SVGSRHPLMQPPQQAPPPPQQQP--------PQQPPQQQPPPPPGLLVRQNSCPPALPRP 381
              G+  P M PP   PP P  +         P QP    P   PG  + Q   P     P
Sbjct: 613  LPGNIGP-MGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNP 671

Query: 382  -QQGEAGTPSG-GL--QDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQA 437
             + G+ G P   GL  Q G P +P    +   P   L      P  +    +  PP    
Sbjct: 672  GRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGP---PGPKGFPGIPGPPGAPG 728

Query: 438  PNQRLQHFDAPP----YMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPG 493
               R+   + PP    +      P F  PG  G      + G+         L P    G
Sbjct: 729  TPGRIG-LEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGA---------LGPKGDRG 778

Query: 494  LPGEFTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQN 553
             PG   PP P        L  P  D                                   
Sbjct: 779  FPG---PPGPPGRTGLDGLPGPKGD----------------------------------- 800

Query: 554  AALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGAG 613
                   +    Q   +  P L  +G  G  G  G+   GP+G         E G  G  
Sbjct: 801  -------VGPNGQPGPMGPPGLPGIGVQGPPGPPGIP--GPIGQPGLHGIPGEKGDPGPP 851

Query: 614  RLGTFEQQAPHLAQESAWFSGPHPPPGDL-LPRRMGGSGLPADCGPHDPSLAPPPPPGGS 672
             L          +       GP  PPG   LP + G SG P   G     + PP PPG  
Sbjct: 852  GLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMG-MMGPPGPPGPL 910

Query: 673  GVLFRGP---------------LQEPMRMPGEGHVPALPSP-GLQFGGSLGGLGQLQSPG 716
            G+  R                 L  P    G    P LP P G      LG  G+   PG
Sbjct: 911  GIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPG 970

Query: 717  AGVGLPSAASER--RPPPPDFATSALGGQPGFPFGAAGRQSTPH--SGPGVNSPPSAGGG 772
               G+P  +  +  +  P D     L GQPG P G  G +  P     PG+  PP   G 
Sbjct: 971  LP-GIPGVSGPKGYQGLPGDPGQPGLSGQPGLP-GPPGPKGNPGLPGQPGLIGPPGLKGT 1028

Query: 773  GGSSG--------GGGGGGAYPPQPDFQ--PSQRTSASKLGALSLGSFNKPSSKDNLFGQ 822
             G  G        G  G    P QP     P Q+      G  S+G    P  K    G+
Sbjct: 1029 IGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPK----GE 1084

Query: 823  SCLAAL--STACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGA-AVAGNPGSDYF 879
              L     +   +  +   G P L  T   K  P            G   ++G PG+   
Sbjct: 1085 PGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGL 1144

Query: 880  PG-------GTAPGAPGPGGPSGTSSS-------------GSKASGPPNPPAQGDGTSLS 919
            PG       G  PG PGP G  G                 G    G P PP     +   
Sbjct: 1145 PGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQK 1204

Query: 920  PNYTLESTSGNDGKPVSGG--GGRG-RGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVS- 975
             +  L    GN G P   G  G  G  G +       SPG   +     P   G PG   
Sbjct: 1205 GDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPG 1264

Query: 976  ----PGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGD--QPDLIGSLD 1029
                PG +   G    G   GE      P    L      +G   L G+  +P L     
Sbjct: 1265 FQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGL----- 1319

Query: 1030 GGAKSDSSSPNVGEFASDE----VSTSYANEDEVSS-SSDNPQALVKASRSPLV----TG 1080
             G K D   P V  F   +    V  S   E E        P  L   S   ++     G
Sbjct: 1320 NGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAG 1379

Query: 1081 SPKLP----------PRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTP 1130
             P +P          P+G   G  GP  PP   G   +          G  G PG PGT 
Sbjct: 1380 PPGIPGQPGLKGLPGPQGP-QGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTR 1438

Query: 1131 GLEQVRTPTSSSGAPPP 1147
            GL+    P    G P P
Sbjct: 1439 GLDGPPGPDGLQGPPGP 1455



 Score = 76.6 bits (187), Expect = 1e-13
 Identities = 154/597 (25%), Positives = 197/597 (32%), Gaps = 122/597 (20%)

Query: 579  GHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGAGRLGTFEQQAPHLAQESAWFSGPHPP 638
            G PG  G  GL   GP G    P  + E GS     L   +    +          P PP
Sbjct: 132  GFPGSPGFPGLQ--GPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGY----------PGPP 179

Query: 639  PGDLLPRRMGGSGLPADCGPHDPS--LAPPPPPG------GSGVLFRGPLQEPMRMPGEG 690
                LP   G +G+P   GP  P   + PP PPG        G+ F+GP  E     GE 
Sbjct: 180  GIQGLP---GPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEK----GEQ 232

Query: 691  HVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALGGQPGFPFGA 750
             +   P P  Q       +  ++      GLP    +R PP P      + G PG P G 
Sbjct: 233  GLQGPPGPPGQISEQKRPI-DVEFQKGDQGLPG---DRGPPGPP----GIRGPPGPPGGE 284

Query: 751  AGRQSTPHSGPGVNSPPSAGGGGGSSGGGG--GGGAYPPQP--DFQPSQRTSASKLGALS 806
             G +      PG    P   G  G  G  G  G   YP +P  D +  Q+      G   
Sbjct: 285  KGEKGE-QGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPG 343

Query: 807  LGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETD 866
            L    +P +   + G+               ++G P L     ++  P  +         
Sbjct: 344  L-VIPRPGTGITI-GEK-------------GNIGLPGLPGEKGERGFPGIQGPPGLPGPP 388

Query: 867  GAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSK-------ASGPPNPPAQGDGTSLS 919
            GAAV G PG   FPG    G  G  GP G S  G         A G P PP    G  + 
Sbjct: 389  GAAVMGPPGPPGFPGER--GQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPA-GPHIP 445

Query: 920  PNYTLESTSGNDGKPVSGG--GGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPG 977
            P+  +    G  G P S G  G +G    K D G           S  P   G PG+ PG
Sbjct: 446  PSDEI-CEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGL-PG 503

Query: 978  QQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGD--QPDLIGSLDG--GAK 1033
               + G        G+  GA  P  K L       GA    G   +P  I +  G  G K
Sbjct: 504  PPGSLGFPGQKGEKGQA-GATGP--KGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDK 560

Query: 1034 SDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGE 1093
             +  SP                                   +P + G P  P +    G 
Sbjct: 561  GELGSPG----------------------------------APGLPGLPGTPGQDGLPGL 586

Query: 1094 HGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPPDEI 1150
             GPK  P  +               G  G PG+PG PGL     P    G  PP  +
Sbjct: 587  PGPKGEPGGITFK------------GERGPPGNPGLPGLPGNIGPMGPPGFGPPGPV 631



 Score = 50.8 bits (120), Expect = 8e-06
 Identities = 90/364 (24%), Positives = 122/364 (33%), Gaps = 69/364 (18%)

Query: 863  NETDGAAVAGNPGSDYFPGGTA----PGAPGPGGPSGTSSSGSKAS----GPPNP----- 909
            ++ D + + G  G   FPG       PG PGP GP G    G K      GPP P     
Sbjct: 36   SKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPR--GQKGDDGIPGPPGPKGIRG 93

Query: 910  PAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSG 969
            P    G   +P   L    G+DG P   G     G +       SPG  F      P   
Sbjct: 94   PPGLPGFPGTPG--LPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPG--FPGLQGPP--- 146

Query: 970  GAPGVSPGQQQASGAAVGGSSAGETRGAP----------TPHEKALTSPSWGKGAELLLG 1019
            G PG+ PG +   G+ +  S  G  +G P           P    +  P    G   L+G
Sbjct: 147  GPPGI-PGMKGEPGSIIMSSLPGP-KGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMG 204

Query: 1020 DQ--PDLIGSLDG------GAKSDSSSPNV-------GEFASDE--VSTSYANEDEVSSS 1062
                P L G          G K +     +       G+ +  +  +   +   D+    
Sbjct: 205  PPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPG 264

Query: 1063 SDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGG 1122
               P         P + G P   P G   GE G +  P   G          P   G  G
Sbjct: 265  DRGPPG------PPGIRGPPG--PPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPG 316

Query: 1123 GPGHPGTPGLEQVRTPTSSSGAPPPDEIHPLEILQAQIQLQRQQFSISEDQPLGLKG--G 1180
             PG+PG PG +  +     +G P P  +         I       +I E   +GL G  G
Sbjct: 317  DPGYPGEPGRDGEKGQKGDTGPPGPPGL--------VIPRPGTGITIGEKGNIGLPGLPG 368

Query: 1181 KKGE 1184
            +KGE
Sbjct: 369  EKGE 372



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 163/666 (24%), Positives = 208/666 (31%), Gaps = 188/666 (28%)

Query: 43   GPPGPVDP-AMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHGH 101
            GPPGP+DP  + + GE    G+   P     +G+      GL   P      GQ    G 
Sbjct: 950  GPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQ-----GLPGDPGQPGLSGQPGLPGP 1004

Query: 102  PGSHHPHQHHPHFGGNFG--GPDPGASCLHGGRLLGYGGAAG--------GLGSQP--PF 149
            PG     + +P   G  G  GP PG     G   +G+ G  G        G+  QP  P 
Sbjct: 1005 PGP----KGNPGLPGQPGLIGP-PGLKGTIGD--MGFPGPQGVEGPPGPSGVPGQPGSPG 1057

Query: 150  AEGYEHMAESQGPESFG-PQRPG-----NLPDFHSSGASSHAVPAPCLPLDQSPNRAASF 203
              G +      G  S G P  PG      LP +  +     +V  P LP       A   
Sbjct: 1058 LPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQ 1117

Query: 204  HGLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGE----APSGHFDMFSPSDSEGQ---- 255
             GLP   G+      P+ ++       L    PGE       GH     P   +G+    
Sbjct: 1118 PGLPGFPGTPGPP-GPKGISGPPGNPGL----PGEPGPVGGGGHPGQPGPPGEKGKPGQD 1172

Query: 256  -LPHYAAGRQVPGG---AFPGASAMPRAAGMVGLSKMHAQPPQQ-QPQQQQQPQQQQQQH 310
             +P  A  +  PG      PG   +P  +G  G   +   P     P  + +P       
Sbjct: 1173 GIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPG------ 1226

Query: 311  GVFFERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVR 370
               F  F G +  P       GS  P ++ P+  P P  Q PP +P  Q  P P G    
Sbjct: 1227 ---FHGFPGVQGPP----GPPGSPGPALEGPKGNPGP--QGPPGRPGFQGLPGPEG---- 1273

Query: 371  QNSCPPALPRPQ--QGEAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFS 428
                PP LP     +GE G P    Q G P LP                           
Sbjct: 1274 ----PPGLPGNGGIKGEKGNPG---QPGLPGLPGLKGD---------------------- 1304

Query: 429  MQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSP 488
             Q PP  Q    R       P +N  K       G  G+     + G      +     P
Sbjct: 1305 -QGPPGLQGNPGR-------PGLNGMK-------GDPGLPGVPGFPGMKGPSGVPGSAGP 1349

Query: 489  SAYPGLPGEFTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQ 548
               PGL G          P GPP   P P  QS+  +          Q            
Sbjct: 1350 EGEPGLIG----------PPGPP-GLPGPSGQSIIIKGDAGPPGIPGQPG---------- 1388

Query: 549  QQRQNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGG 608
                     +K +      Q L  P     G PGD G+ GL           P F+  GG
Sbjct: 1389 ---------LKGLPGPQGPQGLPGPT----GPPGDPGRNGL-----------PGFDGAGG 1424

Query: 609  STGAGRLGTFEQQAPHLAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPPP 668
              G                           PG  LP + G  GL    GP D    PP P
Sbjct: 1425 RKG--------------------------DPG--LPGQPGTRGLDGPPGP-DGLQGPPGP 1455

Query: 669  PGGSGV 674
            PG S V
Sbjct: 1456 PGTSSV 1461


>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 [Homo
            sapiens]
          Length = 2231

 Score =  105 bits (261), Expect = 4e-22
 Identities = 241/1019 (23%), Positives = 332/1019 (32%), Gaps = 237/1019 (23%)

Query: 44   PPGPVDPAMSALGE----PPILGMNMEPYGFHARGHSELHAGGLQAQPV----------- 88
            PPGP  P +S  G+    PP +G   EP G     H  L A G Q  PV           
Sbjct: 115  PPGP--PLLSKPGDEDDAPPKMG---EPAGGRYE-HPGLGALGTQQPPVAVPGGGGGPAA 168

Query: 89   ----HGFFGGQQPHHGHPGSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLG 144
                + ++G   P  G PG     +  P F  + G   PG   +H         AAG  G
Sbjct: 169  VPEFNNYYGSAAPASGGPGG----RAGPCFDQHGGQQSPGMGMMHSAS----AAAAGAPG 220

Query: 145  SQPPFAEGYEHMAESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFH 204
            S  P    +E    SQ     G  RPG        G                 +      
Sbjct: 221  SMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGG------------SGGGGGG 268

Query: 205  GLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAAGRQ 264
            G   + G+ + ++         A         G + +G+  + SP             RQ
Sbjct: 269  GGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSP-------------RQ 315

Query: 265  VPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMP 324
              GG   G    P   G   LSK  A                       F+RF+G  + P
Sbjct: 316  QGGGMMMG----PGGGGAASLSKAAAGSAAGG-----------------FQRFAGQNQHP 354

Query: 325  VGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQG 384
             G  P++     L+  P    P  +      P    P  PP         PP+ P+ Q  
Sbjct: 355  SGATPTLNQ---LLTSPS---PMMRSYGGSYPEYSSPSAPPP--------PPSQPQSQAA 400

Query: 385  EAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQH 444
             AG  +GG Q    M   +    +Y        +    S P  S   P P    +Q    
Sbjct: 401  AAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQ---- 456

Query: 445  FDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSP---SAYPGLPGEFTPP 501
              +P    V KRP+    GS                  + H  P   S YPG  G + PP
Sbjct: 457  -GSPMDPMVMKRPQLYGMGS------------------NPHSQPQQSSPYPG--GSYGPP 495

Query: 502  VPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQ------QQQQQQQQQQQQQRQNAA 555
             P  +P G  +Q   P   +  Q  QQQ   Q  QQ      QQ QQ    QQ Q  +  
Sbjct: 496  GPQRYPIG--IQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLP 553

Query: 556  LMIKQMASRNQQQRLRQPNLAQLGH---------PGDVGQ-----------------GGL 589
               + + S++QQ+   Q +++Q G+         PG                      G 
Sbjct: 554  PQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGS 613

Query: 590  VHGGPVGGLAQ-PNFEREGGSTGAGRLGTFEQQAPHLAQESAWFS----GPHPPP-GDLL 643
            +   P G  A   +     GST +    +   Q+P     S   S    GP P P G  +
Sbjct: 614  IDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPV 673

Query: 644  PRRMGGSGLPADCGPHDPSLAPPPPPGGSG------VLFRGPL-QEPMRMPGEGHVPAL- 695
                  SG P        S  PP PPG          L + P+ QE   M G    P + 
Sbjct: 674  GSNQSRSG-PISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMA 732

Query: 696  --------------PSPGLQFGGSL-------------------GGLGQLQSPGAGVGLP 722
                          PSPG Q    +                   G  G    P A  G+P
Sbjct: 733  QYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVP 792

Query: 723  SAASERRPPPPDFATSA---LGGQ-PGFPFGA--------AGRQSTPHSGPGVNSPPSAG 770
            SA+     P P    SA   + GQ P  P GA        AG Q+ P  G   +  PS+ 
Sbjct: 793  SASYS--GPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSP 850

Query: 771  GGGGSSGGGGGGGAYPPQPDF-QPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALS 829
            G     G G G    PP P   + +Q  +A+ + A +  + ++  S   +     +A+ S
Sbjct: 851  GMSQQGGPGMG----PPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSS 906

Query: 830  TACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETD---GAAVAGNPGSDYFP-----G 881
               Q M       N +   N + PP        N +    G A   +PG    P      
Sbjct: 907  PYSQPM------NNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKAD 960

Query: 882  GTAPGAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSP-NYTLESTSGNDGKPVSGGG 939
            G   G P P   S  S S    S PP P      + +SP + ++ S  G++   +S  G
Sbjct: 961  GKEEGTPQPESKSKDSYSSQGISQPPTPGNLPVPSPMSPSSASISSFHGDESDSISSPG 1019



 Score = 95.1 bits (235), Expect = 4e-19
 Identities = 168/663 (25%), Positives = 217/663 (32%), Gaps = 145/663 (21%)

Query: 514  HPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQP 573
            H    H +LQQQ  Q QQQQQQQQQQQQQQQQQQ     N +L                 
Sbjct: 40   HHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSL----------------- 82

Query: 574  NLAQLGHPGDVGQGGLVHGGPVGGLAQPNFERE----GGSTGAGRLGTFEQQAPHLAQES 629
                              GG  GG  QP  + E    GG+  +   G  +   P L  + 
Sbjct: 83   ------------------GGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKP 124

Query: 630  AWFSGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPGE 689
                   P  G+    R    GL A  G   P   P   PGG G    GP   P      
Sbjct: 125  GDEDDAPPKMGEPAGGRYEHPGLGA-LGTQQP---PVAVPGGGG----GPAAVPEFNNYY 176

Query: 690  GH-VPALPSPGLQFGGSLGGLGQLQSPGAG-VGLPSAASERRPPPPDFATSALGGQPGFP 747
            G   PA   PG + G      G  QSPG G +   SAA+   P   D   ++  G P   
Sbjct: 177  GSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQ 236

Query: 748  FGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSL 807
                   S P +G G       GGGGGS GGGGGGGA                  GA   
Sbjct: 237  CNHYPGYSRPGAGGGGGG--GGGGGGGSGGGGGGGGA------------------GAGGA 276

Query: 808  GSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDG 867
            G+                 A++ A     A+ G               G        + G
Sbjct: 277  GA----------------GAVAAAAAAAAAAAGG--------------GGGGGYGGSSAG 306

Query: 868  AAVAGNPGSDYFPGGTAPGAPGPGGPSGTS--SSGSKASGPPNPPAQGDGTS-LSPNYTL 924
              V  +P      GG     PG GG +  S  ++GS A G      Q    S  +P    
Sbjct: 307  YGVLSSPRQQ---GGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQ 363

Query: 925  ESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGA 984
              TS +      GG                    + +YS+       P     Q  A+GA
Sbjct: 364  LLTSPSPMMRSYGGS-------------------YPEYSSPSAPPPPPSQPQSQAAAAGA 404

Query: 985  AVGG--SSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVG 1042
            A GG  ++AG   G     + A  SP+W    +      P +     G        P +G
Sbjct: 405  AAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQ---RSHPAMSPGTPG--------PTMG 453

Query: 1043 EFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPA 1102
                  +        ++     NP +  + S SP   GS    P G      G +   P 
Sbjct: 454  RSQGSPMDPMVMKRPQLYGMGSNPHSQPQQS-SPYPGGS--YGPPGPQRYPIGIQGRTPG 510

Query: 1103 LGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPPDEIHPLEILQAQIQL 1162
               G+       P  YG  G  G+      +Q + P  S    PP      + L +Q Q 
Sbjct: 511  AMAGMQYPQQQMPPQYGQQGVSGY-----CQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQ 565

Query: 1163 QRQ 1165
            + Q
Sbjct: 566  RYQ 568



 Score = 82.8 bits (203), Expect = 2e-15
 Identities = 181/796 (22%), Positives = 249/796 (31%), Gaps = 114/796 (14%)

Query: 31  NTHFKAPAFHTGGPPGPVDPAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHG 90
           N ++ + A  +GGP G   P     G     GM M            +H+    A    G
Sbjct: 173 NNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGM------------MHSASAAAAGAPG 220

Query: 91  FFGG-QQPHHGHPGS---HHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAG-GLGS 145
                Q  H G+P S   H+P    P  GG  GG   G     GG   G  GA G G G+
Sbjct: 221 SMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGA 280

Query: 146 QPPFAEGYEHMAESQGPESFGPQRPG----NLPDFHSSGASSHAVPAPCLPLDQSPNRAA 201
               A      A   G   +G    G    + P     G            L ++   +A
Sbjct: 281 VAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSA 340

Query: 202 SFHGLPSSSGSDSHSLEPRRVTNQ--GAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHY 259
           +  G    +G + H        NQ   +   +  +Y G  P  +    +P     Q    
Sbjct: 341 A-GGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPE-YSSPSAPPPPPSQPQSQ 398

Query: 260 AAGRQVPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSG 319
           AA      G    A+ M     M G     A P     QQ+  P       G    R  G
Sbjct: 399 AAAAGAAAGGQQAAAGMGLGKDM-GAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQG 457

Query: 320 ARKMPVGLEP----SVGSRHPLMQPPQQA--------PPPPQQQP------------PQQ 355
           +   P+ ++      +GS +P  QP Q +        PP PQ+ P              Q
Sbjct: 458 SPMDPMVMKRPQLYGMGS-NPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQ 516

Query: 356 PPQQQPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFEYPIHRLE 415
            PQQQ PP  G       C     +P   +   P   L      LPSQ  Q   P   + 
Sbjct: 517 YPQQQMPPQYGQQGVSGYCQQG-QQPYYSQQPQPP-HLPPQAQYLPSQSQQRYQPQQDMS 574

Query: 416 NRSMHPYSEPVFS-----------MQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFPGS 464
                  S+P  +           +Q   P   P+      D P              GS
Sbjct: 575 QEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGS 634

Query: 465 AGVDRCASWNGSMHNGA---LDNHLSP--SAYPGLPGEFTPPVPDSFPSGPPLQHPAP-D 518
                  S  G   N A      H SP  S+ PG P     P P   P G       P  
Sbjct: 635 ------TSSQGDQSNPAQSPFSPHASPHLSSIPGGPS----PSPVGSPVGSNQSRSGPIS 684

Query: 519 HQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQL 578
             S+   Q   Q    Q +        Q    ++   +   Q   +  Q   +Q   +  
Sbjct: 685 PASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMS 744

Query: 579 GHPGDVGQGGLVHGGPVGGLAQPNFEREGG--STGAGRLGTFEQQAPHLAQESAWFSGPH 636
            HP     GG +H G +    Q N     G   +  G  G + +   +    SA +SGP 
Sbjct: 745 PHP---SPGGQMHAG-ISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPG 800

Query: 637 PPPGDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPALP 696
           P  G     +M G G              P  P G+  L R P       P  G++ ++ 
Sbjct: 801 PGMGISANNQMHGQG--------------PSQPCGAVPLGRMPSAGMQNRPFPGNMSSMT 846

Query: 697 SPGLQFGGSLGGLGQLQSPGAGVGLPS-------AASERRPPPPDFATSALGGQPGFPFG 749
                   S  G+ Q   PG G  +P+       AA+       + A S  G  PG    
Sbjct: 847 P-------SSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQS 899

Query: 750 AAGRQSTPHSGPGVNS 765
                S+P+S P  NS
Sbjct: 900 GLMASSSPYSQPMNNS 915



 Score = 68.2 bits (165), Expect = 5e-11
 Identities = 125/504 (24%), Positives = 179/504 (35%), Gaps = 69/504 (13%)

Query: 703  GGSLGGLGQ----LQSPGAGVGLPSAASERRPPPPDFATSALGGQPGFP----FGAAGRQ 754
            GG+ GG  Q    ++ P  G    SAA  +  PP     S  G +   P      A GR 
Sbjct: 83   GGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRY 142

Query: 755  STPHSGP-GVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKP 813
              P  G  G   PP A       GGGGG  A P   ++  S   ++   G  +   F++ 
Sbjct: 143  EHPGLGALGTQQPPVA-----VPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQH 197

Query: 814  SSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGN 873
              + +  G   + + S A      + GAP             G     QN  +G     N
Sbjct: 198  GGQQSP-GMGMMHSASAA------AAGAP-------------GSMDPLQNSHEGYP---N 234

Query: 874  PGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGK 933
               +++PG + PGA G GG  G    GS   G       G G   +    + + +     
Sbjct: 235  SQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGG----GAGAGGAGAGAVAAAAAAAAA 290

Query: 934  PVSGGGGRGRGRRKRDSGHVS-PGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSS-- 990
               GGGG G G      G +S P          P  GGA  +S   + A+G+A GG    
Sbjct: 291  AAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLS---KAAAGSAAGGFQRF 347

Query: 991  AGETR---GAPTPHEKALTSPS---WGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEF 1044
            AG+ +   GA     + LTSPS      G        P          +S +++      
Sbjct: 348  AGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAG 407

Query: 1045 ASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAP----- 1099
                 +     +D  +  +    A   A +      SP  P   +G  +  P  P     
Sbjct: 408  GQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKR 467

Query: 1100 PPALGLGIMSNSTSTPDS---YGGG--GGPGHPGTPGLEQVRTPTSSSGAPPPDEIHPLE 1154
            P   G+G  SN  S P     Y GG  G PG    P   Q RTP + +G   P +  P +
Sbjct: 468  PQLYGMG--SNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQ 525

Query: 1155 ILQAQI----QLQRQQFSISEDQP 1174
              Q  +    Q  +Q +   + QP
Sbjct: 526  YGQQGVSGYCQQGQQPYYSQQPQP 549



 Score = 57.8 bits (138), Expect = 7e-08
 Identities = 235/1074 (21%), Positives = 314/1074 (29%), Gaps = 206/1074 (19%)

Query: 335  HPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQ 394
            H L Q   Q     QQQ  QQ  QQQ   P   +   NS             G   GG  
Sbjct: 46   HALQQQLNQFQQQQQQQQQQQQQQQQQQHP---ISNNNSL------------GGAGGGAP 90

Query: 395  DGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVA 454
              GP         E P H     S             PP     ++     DAPP M   
Sbjct: 91   QPGP-------DMEQPQHGGAKDSA------AGGQADPPGPPLLSKPGDEDDAPPKMGEP 137

Query: 455  KRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPG--EFTPPVPDSFPSGPPL 512
               R++ PG                GAL     P A PG  G     P   + + S  P 
Sbjct: 138  AGGRYEHPGL---------------GALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPA 182

Query: 513  QHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQ 572
                P  ++     Q   QQ                       L        N Q     
Sbjct: 183  SG-GPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCN-HY 240

Query: 573  PNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGAGRLGTFEQQAPHLAQESA-- 630
            P  ++ G  G  G GG   GG  GG         GG  GAG  G     A   A  +A  
Sbjct: 241  PGYSRPGAGGGGGGGGGGGGGSGGGGG-------GGGAGAGGAGAGAVAAAAAAAAAAAG 293

Query: 631  -----WFSGPHPPPGDLLPRRMGGSGL---PADCGPHDPSLAPPPPPGGSGVLFRGPLQE 682
                  + G     G L   R  G G+   P   G    S A      G    F G  Q 
Sbjct: 294  GGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQH 353

Query: 683  PM-RMPGEGHVPALPSPGLQ-FGGSL-----------------------GGLGQLQSPGA 717
            P    P    +   PSP ++ +GGS                        G     Q   A
Sbjct: 354  PSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAA 413

Query: 718  GVGLPS-------------AASERRPPP---PDFATSALGGQPGFPFGAA--------GR 753
            G+GL               AA+++R  P   P      +G   G P            G 
Sbjct: 414  GMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGM 473

Query: 754  QSTPHSGPGVNSPPSAGGGG------------GSSGGGGGGGAYPPQPDFQPSQRTSASK 801
             S PHS P  +SP   G  G            G + G   G  YP Q    P Q      
Sbjct: 474  GSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQ--MPPQYGQQGV 531

Query: 802  LGALSLGS---FNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKR 858
             G    G    +++     +L  Q+    L +  Q         +      +  PP    
Sbjct: 532  SGYCQQGQQPYYSQQPQPPHLPPQA--QYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPG 589

Query: 859  K-------LSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPA 911
            K       L Q E   +    +   D  P GT          SG++SS    S P   P 
Sbjct: 590  KPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSP- 648

Query: 912  QGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGA 971
                   SP+ +    S   G P     G   G  +  SG +SP        A+      
Sbjct: 649  ------FSPHAS-PHLSSIPGGPSPSPVGSPVGSNQSRSGPISP--------ASIPGSQM 693

Query: 972  PGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSLDGG 1031
            P   PG Q  S      SS      +P P E+   + +         G Q        G 
Sbjct: 694  PPQPPGSQSES------SSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQT------GP 741

Query: 1032 AKSDSSSPN------VGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLP 1085
            + S   SP       +  F     S +Y  +     S   PQ     SR P  +G P   
Sbjct: 742  SMSPHPSPGGQMHAGISSFQQSNSSGTYGPQ----MSQYGPQG--NYSRPPAYSGVPSAS 795

Query: 1086 PRGVGAGE----------HGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQV 1135
              G G G            GP  P  A+ LG M ++      + G      P +PG+ Q 
Sbjct: 796  YSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQ 855

Query: 1136 RTPTSSSGAPPP------DEIHPLEILQAQIQLQRQQFSISEDQPLGLKGGKK--GECAV 1187
              P    G P P       E     +  A    Q +Q S       GL        +   
Sbjct: 856  GGP--GMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMN 913

Query: 1188 GASGAQNGDSELGSCCSEAVKSAMSTIDLDSLMAEHSAAWYMPADKALVDSADDDKTLAP 1247
             +S   N  +   S     V S+ +++ L  +M+   +   +P        AD  +   P
Sbjct: 914  NSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPL------KADGKEEGTP 967

Query: 1248 WEKAKPQNPNSKEAHDLPANKASASQPGSHLQCLSVHCTDDVGDAKARASVPTW 1301
              ++K ++  S +    P    +   P S +   S   +   GD     S P W
Sbjct: 968  QPESKSKDSYSSQGISQPPTPGNLPVP-SPMSPSSASISSFHGDESDSISSPGW 1020



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 109/462 (23%), Positives = 164/462 (35%), Gaps = 81/462 (17%)

Query: 95   QQPHHGHPGSHHPHQHHPHFGGNFGGPDPG-------ASCLHGGRLLGYGGAAGGLGSQP 147
            Q P   + GS    Q     G N     PG       AS  HG      GG +  +    
Sbjct: 1161 QPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHD 1220

Query: 148  PFAEGYEHMAESQGPE--SFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHG 205
            PF++    +++S  P+  S  P  P      +  G S   +P     +   PN+   F G
Sbjct: 1221 PFSD----VSDSSFPKRNSMTPNAP------YQQGMS---MPDVMGRMPYEPNKDP-FGG 1266

Query: 206  LPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAA---- 261
            +    GS    +   ++ N    D   YN   ++PSG          + Q P+ A+    
Sbjct: 1267 MRKVPGSSEPFMTQGQMPNSSMQDM--YN---QSPSGAMSNLGMGQRQ-QFPYGASYDRR 1320

Query: 262  ----GRQVPGGAFPGASAMPRAAGMVGLS------KMHAQ----PPQQQPQ----QQQQP 303
                G+Q PG   P +   P      GL       K H      PP ++ +      Q  
Sbjct: 1321 HEPYGQQYPGQG-PPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYS 1379

Query: 304  QQQQQQHGVFFERFSGARKMPV-GLEPSVGSRHPLMQPPQ---QAPPPPQQQPPQQPPQQ 359
             QQQ+ +  +   +SG  + P+ G  P   SR  +  P Q      PP     P Q    
Sbjct: 1380 SQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSS 1439

Query: 360  QPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFEY--PIHRLENR 417
            + P       R +     +P P Q   G P G  Q   P  P  +   +   P  R+ + 
Sbjct: 1440 EGPQQNMWAARND-----MPYPYQNRQG-PGGPTQ--APPYPGMNRTDDMMVPDQRINHE 1491

Query: 418  SMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSM 477
            S  P       +    P  + +  +Q    PP      +P +  P S       + + + 
Sbjct: 1492 SQWPSH-----VSQRQPYMSSSASMQPITRPP------QPSYQTPPSLPNHISRAPSPAS 1540

Query: 478  HNGALDNHLSPSAYPGLPG----EFTPPVPDSFPSGPPLQHP 515
               +L+N +SPS  P LP     +  P VP S  +GPP Q P
Sbjct: 1541 FQRSLENRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQPP 1582



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 33/102 (32%), Positives = 40/102 (39%), Gaps = 14/102 (13%)

Query: 294 QQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQPP 353
           QQQ QQQQQ QQQQQQH +      G            G   P   P  + P     +  
Sbjct: 58  QQQQQQQQQQQQQQQQHPISNNNSLG----------GAGGGAPQPGPDMEQPQHGGAKDS 107

Query: 354 QQPPQQQPPPPPGLLVR---QNSCPPALPRPQQGEAGTPSGG 392
               Q  PP PP LL +   ++  PP +  P  G    P  G
Sbjct: 108 AAGGQADPPGPP-LLSKPGDEDDAPPKMGEPAGGRYEHPGLG 148



 Score = 36.2 bits (82), Expect = 0.21
 Identities = 39/161 (24%), Positives = 64/161 (39%), Gaps = 12/161 (7%)

Query: 638  PPGDLLPRRMGGSGLPADCGPHDP--SLAPPPPPGGSGVLFRGPLQEPMRMPGE-GHVPA 694
            P G + P + G S   +    HDP   ++    P  + +    P Q+ M MP   G +P 
Sbjct: 1201 PHGQMTPMQGGRS---STISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPY 1257

Query: 695  LPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASE---RRPPPPDFATSALGGQPGFPFGAA 751
             P+    FGG     G  +       +P+++ +    + P    +   +G +  FP+GA+
Sbjct: 1258 EPNKD-PFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGAS 1316

Query: 752  GRQSTPHSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQ 792
                  H   G   P      G    GG   G YP QP+++
Sbjct: 1317 --YDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYK 1355



 Score = 33.1 bits (74), Expect = 1.8
 Identities = 81/347 (23%), Positives = 117/347 (33%), Gaps = 83/347 (23%)

Query: 51   AMSALGEPPILGMNME-PYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHGHPGSHHPHQ 109
            AMS LG    +G   + PYG     +   H    Q  P  G   GQ P+ GH    +P Q
Sbjct: 1299 AMSNLG----MGQRQQFPYG---ASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQ 1351

Query: 110  --HHPHFGGNFGGPDPGASCLHGGRLLG-------------YGGAAGGLGSQPPFAEGYE 154
              +  H  G +G P    +  H G +               YGG+  G   +P       
Sbjct: 1352 PNYKRHMDGMYGPP----AKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRP------- 1400

Query: 155  HMAESQGPESFGPQR---PGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSG 211
               + Q P  +  +R   PG +         +H +P   +     P +++S  G   +  
Sbjct: 1401 --IQGQYPYPYSRERMQGPGQI--------QTHGIPPQMM---GGPLQSSSSEGPQQNMW 1447

Query: 212  SDSHSLEPRRVTNQGAVDSLEY-NYPGEAPSGHFDMFSPS---DSEGQLPHYAAGRQVPG 267
            +  + +       QG     +   YPG   +   DM  P    + E Q P + + RQ   
Sbjct: 1448 AARNDMPYPYQNRQGPGGPTQAPPYPGMNRTD--DMMVPDQRINHESQWPSHVSQRQ--- 1502

Query: 268  GAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQH-GVFFERFSGARKMPVG 326
                    M  +A M        QP  + PQ   Q       H        S  R +   
Sbjct: 1503 ------PYMSSSASM--------QPITRPPQPSYQTPPSLPNHISRAPSPASFQRSLENR 1548

Query: 327  LEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPP-------PPG 366
            + PS     P M+  +  P  P  Q    PP  QPPP       PPG
Sbjct: 1549 MSPSKSPFLPSMKMQKVMPTVPTSQVTGPPP--QPPPIRREITFPPG 1593


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score =  104 bits (259), Expect = 6e-22
 Identities = 292/1206 (24%), Positives = 376/1206 (31%), Gaps = 234/1206 (19%)

Query: 43   GPPGPVDPAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPHH--G 100
            GPPGP  P       PP LG N  P   +  G+ E   GG+    V G  G   P    G
Sbjct: 142  GPPGPPGPP-----GPPGLGGNFAPQLSY--GYDEKSTGGIS---VPGPMGPSGPRGLPG 191

Query: 101  HPGSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLGSQ-PPFAEGYEHMAES 159
             PG+  P          F GP PG          G  GA+G +G + PP   G       
Sbjct: 192  PPGAPGPQ--------GFQGP-PGEP--------GEPGASGPMGPRGPPGPPG----KNG 230

Query: 160  QGPESFGPQRPGNLPDFHSSGASSHAVPAPC-LPLDQSPNRAASFHGLPSSSGSDSHSLE 218
               E+  P RPG        GA    +P    LP  +     +   G    +G      E
Sbjct: 231  DDGEAGKPGRPGERGPPGPQGA--RGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGE 288

Query: 219  PRRVTNQGAVDSL-EYNYPGEAPSGHFDMFSPSDSEGQLPHYAAGRQVPGGAFPGASAMP 277
            P      GA   +     PGE   G      P+ + G     A G   P G   G +  P
Sbjct: 289  PGSPGENGAPGQMGPRGLPGER--GRPGAPGPAGARGN--DGATGAAGPPGP-TGPAGPP 343

Query: 278  RAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRHPL 337
               G VG +K  A P  Q P+  + PQ  + + G      +       G +   G++   
Sbjct: 344  GFPGAVG-AKGEAGP--QGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGAN 400

Query: 338  MQPP-QQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDG 396
              P    AP  P  + P  P  Q P  PPG            P+   GE G P      G
Sbjct: 401  GAPGIAGAPGFPGARGPSGP--QGPGGPPG------------PKGNSGEPGAPGSKGDTG 446

Query: 397  GPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKR 456
                P        P    E        EP  +    PP +      + F     +   K 
Sbjct: 447  AKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKG 506

Query: 457  PRFD--FPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSFPSGPPLQH 514
            P  +   PG AG        G      L      +  PG PG    P   + P GP  Q 
Sbjct: 507  PAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPG----PDGKTGPPGPAGQD 562

Query: 515  PAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPN 574
              P                                             +R Q   +  P 
Sbjct: 563  GRPGPPG--------------------------------------PPGARGQAGVMGFPG 584

Query: 575  -LAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTG----AGRLGTFEQQAPHLAQES 629
                 G PG  G+ G+   GP G +     + E G+ G    AG  G   +Q P  +   
Sbjct: 585  PKGAAGEPGKAGERGVP--GPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGF 642

Query: 630  AWFSGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPP-----------PPGGSGVLFRG 678
                GP  PPG+    + G  G+P D G   PS A              PPG +G   RG
Sbjct: 643  QGLPGPAGPPGEA--GKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGP--RG 698

Query: 679  PLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPG--AGVGLPSAASERRPPPPDFA 736
                P     +G   A  +PG Q    L G+     PG     GLP    +R    P  A
Sbjct: 699  ANGAPGNDGAKGDAGAPGAPGSQGAPGLQGM-----PGERGAAGLPGPKGDRGDAGPKGA 753

Query: 737  TSALG-----------GQPGFPFGAAGRQSTPHSGP-GVNSPPSAGGGGGSSGGGG---- 780
              + G           G PG P GA G +    SGP G   P  A G  G  G  G    
Sbjct: 754  DGSPGKDGVRGLTGPIGPPG-PAGAPGDKG--ESGPSGPAGPTGARGAPGDRGEPGPPGP 810

Query: 781  GGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLG 840
             G A PP  D QP  +      GA        P+      G              I ++G
Sbjct: 811  AGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGP-------------IGNVG 857

Query: 841  APNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTA--PGAPGPGGPSG--- 895
            AP          PP      +      A   G PG    P G A  PG PGP G  G   
Sbjct: 858  APGAKGARGSAGPPG-----ATGFPGAAGRVGPPG----PSGNAGPPGPPGPAGKEGGKG 908

Query: 896  ----TSSSGSKAS-GPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGG--GGRG----RG 944
                T  +G     GPP PP    G   SP    +  +G  G P   G  G RG     G
Sbjct: 909  PRGETGPAGRPGEVGPPGPPGPA-GEKGSPG--ADGPAGAPGTPGPQGIAGQRGVVGLPG 965

Query: 945  RRKRDSGHVSPGTFFDKYSAAPDSG----------GAPGVS--PGQQQASGAAVGGSSAG 992
            +R        PG   +     P             G PG++  PG+    GA     S G
Sbjct: 966  QRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPG 1025

Query: 993  ETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSSPN-----VGEFASD 1047
                     ++  T P+   GA    G  P  +G          + P      VG   + 
Sbjct: 1026 RDGSPGAKGDRGETGPAGPPGAPGAPG-APGPVGPAGKSGDRGETGPAGPAGPVGPVGAR 1084

Query: 1048 EVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVG-------AGEHGPKAPP 1100
              +       +   + +     +K  R       P  PP   G       +G  GP+ PP
Sbjct: 1085 GPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPP 1144

Query: 1101 PALG-------------LGIMSNSTSTPDS--YGGGGGPGHPGTPGLEQVRTPTSSSGAP 1145
             + G             +G       T D+   G  G PG PG PG        S    P
Sbjct: 1145 GSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFLPQP 1204

Query: 1146 PPDEIH 1151
            P ++ H
Sbjct: 1205 PQEKAH 1210



 Score = 99.0 bits (245), Expect = 3e-20
 Identities = 219/905 (24%), Positives = 273/905 (30%), Gaps = 167/905 (18%)

Query: 326  GLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPAL-----PR 380
            G+E   G   P   P   A PP +   P QP    PP PPG        PP L     P+
Sbjct: 109  GVEGPKGDTGP-RGPRGPAGPPGRDGIPGQPGLPGPPGPPG-----PPGPPGLGGNFAPQ 162

Query: 381  PQQGEAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQ 440
               G     +GG+   GPM PS                             P P  AP  
Sbjct: 163  LSYGYDEKSTGGISVPGPMGPSGPRGL------------------------PGPPGAPGP 198

Query: 441  RLQHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTP 500
              Q F  PP            PG  G        G       +     +  PG PGE  P
Sbjct: 199  --QGFQGPP----------GEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGP 246

Query: 501  PVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQ 560
            P P     G P     P    ++  +        +        + +     +N A    Q
Sbjct: 247  PGPQG-ARGLPGTAGLP---GMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGA--PGQ 300

Query: 561  MASRNQQQRLRQPNLAQLGHPGDVG-------QGGLVHGGPVGGLAQPNFEREGGSTG-A 612
            M  R       +P     G PG  G        G     GP G    P F    G+ G A
Sbjct: 301  MGPRGLPGERGRP-----GAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEA 355

Query: 613  GRLGTFEQQAPHLAQES------AWFSGPHPPPG-DLLPRRMGGSGLP------------ 653
            G  G    + P   +        A  +GP   PG D  P   G +G P            
Sbjct: 356  GPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGAR 415

Query: 654  ADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPALPSPG-LQFGGSLGGLGQL 712
               GP  P   PP P G SG        EP     +G   A   PG +   G  G  G+ 
Sbjct: 416  GPSGPQGPG-GPPGPKGNSG--------EPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEE 466

Query: 713  QSPGA-----GVGLPSAASERRPPPPDFATSALG--------GQPGFPFGAAGRQSTPHS 759
               GA       GLP    ER  P       A G        G+ G P G AG + +P  
Sbjct: 467  GKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSP-GPAGPKGSPGE 525

Query: 760  G--PGVNSPPSAGGGGGSSGG-GGGGGAYPPQP---DFQPSQRTSASKLGALSLGSFNKP 813
               PG    P A G  GS G  G  G   PP P   D +P         G   +  F  P
Sbjct: 526  AGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGP 585

Query: 814  SSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGN 873
                   G+    A          ++G    +     + PP       +    G   AG+
Sbjct: 586  KGAAGEPGK----AGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGP--AGS 639

Query: 874  PGSDYFPGGTAP----------------GAPGPGGPSGTSSSGSK--ASGPPNPPAQGDG 915
            PG    PG   P                GAPGP G  G      +    GPP P      
Sbjct: 640  PGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGA 699

Query: 916  TSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVS 975
                 N   +  +G  G P S G    +G          PG   D+  A P   GA G S
Sbjct: 700  NGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPK--GADG-S 756

Query: 976  PGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSD 1035
            PG+    G        G    A  P +K  + PS   G     G           G + +
Sbjct: 757  PGKDGVRGLT---GPIGPPGPAGAPGDKGESGPSGPAGPTGARGAP---------GDRGE 804

Query: 1036 SSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVG----- 1090
               P    FA          + +  +  +   A  K    P     P  PP  +G     
Sbjct: 805  PGPPGPAGFAGPP-----GADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAP 859

Query: 1091 --AGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSG-APPP 1147
               G  G   PP A G    +     P   G  G PG PG  G E  + P   +G A  P
Sbjct: 860  GAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRP 919

Query: 1148 DEIHP 1152
             E+ P
Sbjct: 920  GEVGP 924



 Score = 84.3 bits (207), Expect = 7e-16
 Identities = 159/628 (25%), Positives = 213/628 (33%), Gaps = 118/628 (18%)

Query: 579  GHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTG-AGRLGTFEQQAPHLAQESAWFSGPHP 637
            G PG+ G+ G    GP+G    P    + G  G AG+ G   ++ P   Q +    G   
Sbjct: 203  GPPGEPGEPGA--SGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAG 260

Query: 638  PPGDLLPRRMGG-SGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPALP 696
             PG    R   G  G   D GP  P    P  PG +G   +     P  +PGE   P  P
Sbjct: 261  LPGMKGHRGFSGLDGAKGDAGPAGPK-GEPGSPGENGAPGQ---MGPRGLPGERGRPGAP 316

Query: 697  SPGLQFG--GSLGGLGQL--QSPGAGVGLPSAASERRPPPPDFATSALG-----GQPG-- 745
             P    G  G+ G  G      P    G P A   +    P     + G     G+PG  
Sbjct: 317  GPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPP 376

Query: 746  FPFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGGGG-------AYPPQPDFQPSQRTS 798
             P GAAG    P   PG +  P A G  G+ G  G  G       + P  P   P  + +
Sbjct: 377  GPAGAAG----PAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGN 432

Query: 799  ASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPP---- 854
            + + GA        P SK +                     GA         + PP    
Sbjct: 433  SGEPGA--------PGSKGDT--------------------GAKGEPGPVGVQGPPGPAG 464

Query: 855  -EGKRKLSQNETDGAAVAG------NPGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGPP 907
             EGKR  ++ E     + G       PGS  FPG  A G  GP GP+G   S   A GP 
Sbjct: 465  EEGKRG-ARGEPGPTGLPGPPGERGGPGSRGFPG--ADGVAGPKGPAGERGSPGPA-GPK 520

Query: 908  NPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPD 967
              P +      +     +  +G+ G P   G     G   +D     PG         P 
Sbjct: 521  GSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGP--------PG 572

Query: 968  SGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGS 1027
            + G  GV  G     GAA     AGE RG P P       P+ GK  E      P   G 
Sbjct: 573  ARGQAGVM-GFPGPKGAAGEPGKAGE-RGVPGP--PGAVGPA-GKDGEAGAQGPPGPAGP 627

Query: 1028 L-DGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPP 1086
              + G +  + SP              A +          Q +     +P  +G+     
Sbjct: 628  AGERGEQGPAGSPGFQGLPGPAGPPGEAGKP-------GEQGVPGDLGAPGPSGARG--E 678

Query: 1087 RGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGT---PGLEQV-------- 1135
            RG   GE G + PP   G    + +     + G  G PG PG+   PGL+ +        
Sbjct: 679  RGF-PGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAG 737

Query: 1136 ----------RTPTSSSGAPPPDEIHPL 1153
                        P  + G+P  D +  L
Sbjct: 738  LPGPKGDRGDAGPKGADGSPGKDGVRGL 765



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 89/335 (26%), Positives = 112/335 (33%), Gaps = 64/335 (19%)

Query: 854  PEGKRKLSQNETDGA-------------AVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSG 900
            P+G    +  ET G                AG PG D  PG   PG PGP GP G     
Sbjct: 96   PDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPG--QPGLPGPPGPPG----- 148

Query: 901  SKASGPPNPPAQGDGTS--LSPNYTLESTSGNDGKPVSGGGGRG-RGRRKRDSGHVSPGT 957
                 PP PP  G   +  LS  Y  +ST G     +S  G  G  G R       +PG 
Sbjct: 149  -----PPGPPGLGGNFAPQLSYGYDEKSTGG-----ISVPGPMGPSGPRGLPGPPGAPGP 198

Query: 958  FFDKYSAAPDSGGAPGVSP--GQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAE 1015
                +   P   G PG S   G +   G        GE      P E+    P   +G  
Sbjct: 199  --QGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLP 256

Query: 1016 LLLGDQPDLIG-----SLDG--------GAKSDSSSPNVGEFASDEVSTSYANEDEVSSS 1062
               G  P + G      LDG        G K +  SP     A  ++       +     
Sbjct: 257  GTAG-LPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENG-APGQMGPRGLPGERGRPG 314

Query: 1063 SDNP------QALVKASRSPLVTGSPKLP--PRGVGA-GEHGPKAPPPALGLGIMSNSTS 1113
            +  P           A+  P  TG    P  P  VGA GE GP+ P  + G   +     
Sbjct: 315  APGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPG 374

Query: 1114 TPDSYGGGGGPGHPGT---PGLEQVRTPTSSSGAP 1145
             P   G  G  G+PG    PG +        +GAP
Sbjct: 375  PPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAP 409


>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
          Length = 2285

 Score =  103 bits (256), Expect = 1e-21
 Identities = 288/1239 (23%), Positives = 401/1239 (32%), Gaps = 273/1239 (22%)

Query: 8    EPQVNSRNAGQGERNFNETGLSMNTHFKAPAFHTGGPPG-----PVDPAMSALGEPPILG 62
            EP + + N   G R       ++N +   P    GG        P   A +AL  PP  G
Sbjct: 97   EPDLKNSNGNAGPRP------ALNNNLTEPPGGGGGGSSDGVGAPPHSAAAAL-PPPAYG 149

Query: 63   MNMEPYG-------------FHARGHSELHAGGLQAQPVHGFFGGQQPHHGHPGSHHPH- 108
               +PYG             FH + H    + GL A    G  GG +P+ G   + H H 
Sbjct: 150  FG-QPYGRSPSAVAAAAAAVFHQQ-HGGQQSPGLAALQSGGG-GGLEPYAGPQQNSHDHG 206

Query: 109  ----QHHPHFGGNFGGPDPGASCLHGGRLLGY--GGAAGGLGSQPPFAEGYEHMAESQGP 162
                Q++ ++      P P  +        G    GAA   GS+PP +      + S   
Sbjct: 207  FPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSS---ASASSSS 263

Query: 163  ESFGPQRPGNLPDFHSSGASSHAVPAPCLP----LDQSPNRAASFHGLPSSSGSDSHSLE 218
             SF  QR G +     S A          P    L  SP+ A  + G P    S      
Sbjct: 264  SSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSG----- 318

Query: 219  PRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAAGRQVPGGAFPGASAMPR 278
                   G  D       G A  G  DM   S   G     AA     GGA   +   P 
Sbjct: 319  -------GPQD-------GGAGKGPADM--ASQCWGAAAAAAAAAAASGGAQQRSHHAPM 362

Query: 279  AAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRHPLM 338
            + G  G      QP  + PQ      Q                         +G   P  
Sbjct: 363  SPGSSGGG---GQPLARTPQPSSPMDQ-------------------------MGKMRP-- 392

Query: 339  QPPQQAPPPPQQQPPQQPPQQ---QPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQ- 394
            QP     P  QQQ P   PQQ    P  P G     +  P   P   QG A +  GGL  
Sbjct: 393  QPYGGTNPYSQQQGPPSGPQQGHGYPGQPYG-----SQTPQRYPMTMQGRAQSAMGGLSY 447

Query: 395  --------DGGPMLPSQHAQFEYPIHRLENRSMHPYSE-PVFSMQHPPPQQAPNQRLQHF 445
                      GP    Q  Q  Y       +S HP  + P +S Q  PP Q P+ +    
Sbjct: 448  TQQIPPYGQQGPSGYGQQGQTPY----YNQQSPHPQQQQPPYSQQ--PPSQTPHAQ---- 497

Query: 446  DAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDS 505
              P Y                                     P + P       PP    
Sbjct: 498  --PSYQQ----------------------------------QPQSQPPQLQSSQPPYSQQ 521

Query: 506  FPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMAS-- 563
             PS PP Q     + S Q   QQ  Q Q    Q Q Q   QQQQ +Q A   + Q A+  
Sbjct: 522  -PSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYP 580

Query: 564  RNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGAGRLGTFEQQAP 623
            + Q Q+ +Q   +Q   P            P   L+Q +F  +  S  +       Q+  
Sbjct: 581  QPQSQQSQQTAYSQQRFP------------PPQELSQDSFGSQASSAPSMTSSKGGQEDM 628

Query: 624  HLAQESAWFSGPHPPPG-DLLPRRMGG--------SGLPADCG---------------PH 659
            +L+ +S   S P      D LP    G        SG+ +  G               PH
Sbjct: 629  NLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPH 688

Query: 660  DPSL-APPPPPGGSGVLF----RGPLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQS 714
             P +  P P P GS         GPL  P  +PG    P  PS      G    +     
Sbjct: 689  LPGIRGPSPSPVGSPASVAQSRSGPL-SPAAVPGNQMPPRPPS------GQSDSIMHPSM 741

Query: 715  PGAGVGLPSAASERRPPPPDFATSALGGQPG---FPFGAAGRQSTPHSGPGVNSPPSAGG 771
              + +       +R P  P +++     QPG    P   +G Q   H+G G     S G 
Sbjct: 742  NQSSIAQDRGYMQRNPQMPQYSSP----QPGSALSPRQPSGGQI--HTGMGSYQQNSMGS 795

Query: 772  GGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTA 831
             G   G  G  G YP QP++      +    G    G  N   +   + GQ  +    T 
Sbjct: 796  YGPQGGQYGPQGGYPRQPNYNALPNANYPSAG--MAGGINPMGAGGQMHGQPGIPPYGTL 853

Query: 832  CQNMI--ASLG----APNL-----NVTFNKKNPPEGKRKLSQNETDGAAVAGN------P 874
                +  AS+G     PN+      V      PP G  + +Q       VA N      P
Sbjct: 854  PPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPP 913

Query: 875  GSDYFPGGTAPGAPGPGGPSGTS-SSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDG- 932
            G   +P     G  G G P G   +S +    P  PP    GT  + +  + ++    G 
Sbjct: 914  G---YPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGL 970

Query: 933  -----KPVSGGGGRGRGRRKRDS---GHVSPGTFFDKYSAAPDSGGAP----GVSPGQQQ 980
                  P +    +  G  K +S      S  T  +K +   + GG P     V      
Sbjct: 971  GDVKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKITKLYELGGEPERKMWVDRYLAF 1030

Query: 981  ASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQP--DLIGSLDGGAKSDSSS 1038
                A+G ++       P    +   S     G   +  ++   +L  +L+ G  S ++S
Sbjct: 1031 TEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNLNVGTSSSAAS 1090

Query: 1039 PNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKL-PPRGVGAGE-HGP 1096
                      +   YA E ++    D P  +  A+ S      PK+ PP   G+G   GP
Sbjct: 1091 ----SLKKQYIQCLYAFECKIERGEDPPPDIFAAADSK--KSQPKIQPPSPAGSGSMQGP 1144

Query: 1097 KAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQV 1135
            + P           STS+  + GG   P  P +    Q+
Sbjct: 1145 QTP----------QSTSSSMAEGGDLKPPTPASTPHSQI 1173



 Score = 84.3 bits (207), Expect = 7e-16
 Identities = 266/1237 (21%), Positives = 393/1237 (31%), Gaps = 268/1237 (21%)

Query: 3    GLDQFE-PQVNSRNAGQGERNFNETGLSMNTHFK-APAFHTGGPPG--PVDPAMSALGEP 58
            GL+ +  PQ NS + G     +N    + + +   APA+    P G  P   A +A G  
Sbjct: 191  GLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSK 250

Query: 59   PILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHGHPGSHHP----------- 107
            P       P    A   S   +    AQ   G  GG  P     G+  P           
Sbjct: 251  P-------PPSSSASASS---SSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLT 300

Query: 108  -------HQHHPHFGGNF-GGPDPGASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHMAES 159
                   +Q +P  GG++ GGP  G +      +      A    +    A G       
Sbjct: 301  SPSSARGYQGYP--GGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSH 358

Query: 160  QGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDSHSLE- 218
              P S G    G  P   +        P P  P+DQ        +G     G++ +S + 
Sbjct: 359  HAPMSPGSSGGGGQPLART--------PQPSSPMDQMGKMRPQPYG-----GTNPYSQQQ 405

Query: 219  -PRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAAG----RQVPGGAFPGA 273
             P     QG      + YPG+          P   +G+      G    +Q+P     G 
Sbjct: 406  GPPSGPQQG------HGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGP 459

Query: 274  SAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGS 333
            S   +       ++    P QQQP   QQP  Q                     +PS   
Sbjct: 460  SGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPH-----------------AQPSY-Q 501

Query: 334  RHPLMQPPQ-QAPPPPQQQPPQQPPQQQPPPP-PGLLVRQNSCPPALPRPQQGEAGTPSG 391
            + P  QPPQ Q+  PP  Q P QPP QQ P P P         P + P   Q +A +P  
Sbjct: 502  QQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQ 561

Query: 392  GLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYM 451
              Q   P   +   Q  YP  + +      YS+  F    PP + + +       + P M
Sbjct: 562  QQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFP---PPQELSQDSFGSQASSAPSM 618

Query: 452  NVAK------------RPRF--DFPGS---------------AGVDRCASWNGSMHNGAL 482
              +K            RP    D  GS                     +S  G   N A 
Sbjct: 619  TSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPA- 677

Query: 483  DNHLSPSAYPGLPGEFTP-PVP----------------------DSFPSGPP------LQ 513
             +  SP   P LPG   P P P                      +  P  PP      + 
Sbjct: 678  QSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIM 737

Query: 514  HPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQR---- 569
            HP+ +  S+ Q +   Q+  Q  Q    Q       ++ +   +   M S  Q       
Sbjct: 738  HPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYG 797

Query: 570  ------------LRQPNLAQL-----------GHPGDVGQGGLVHGGPVGGLAQPNFERE 606
                         RQPN   L           G    +G GG +HG P  G+  P     
Sbjct: 798  PQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQP--GIP-PYGTLP 854

Query: 607  GGSTGAGRLGTFEQQAPHLAQESAWF-SGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAP 665
             G      +G      P++A       SG  PPPG +  R+   + +      +     P
Sbjct: 855  PGRMSHASMGN-RPYGPNMANMPPQVGSGMCPPPGGM-NRKTQETAVAMHVAANSIQNRP 912

Query: 666  PP-------------PPGGSGVLFRGPLQEPMRMP-GEGHVPALPSPGLQFGGSLGGLGQ 711
            P              PP G G+     +  P   P   G   A  S G+     + GLG 
Sbjct: 913  PGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGLGD 972

Query: 712  LQSPGA------GVGLPSAASERRPPPPDFATSA-------LGGQPGFPFGAAGRQS-TP 757
            ++   A        G P   S+ +       T+        LGG+P          + T 
Sbjct: 973  VKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKITKLYELGGEPERKMWVDRYLAFTE 1032

Query: 758  HSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSK- 816
                G+ + P+ G                 +P        S  ++G L+  + NK   + 
Sbjct: 1033 EKAMGMTNLPAVGR----------------KPLDLYRLYVSVKEIGGLTQVNKNKKWREL 1076

Query: 817  -DNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPE----GKRKLSQNETDGAAVA 871
              NL   +  +A S+  +  I  L A    +   +  PP+       K SQ +    + A
Sbjct: 1077 ATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPA 1136

Query: 872  GNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGND 931
            G+               GP  P  TSSS ++      P       S  P     S S + 
Sbjct: 1137 GSGSMQ-----------GPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSV 1185

Query: 932  GKPVSGGGGRGRGRRKRDSGHVSPG--------TFFDKYSAAPDS----------GGAPG 973
            G   +   G     +KR+S   +PG            + S  P+           G  P 
Sbjct: 1186 GIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPF 1245

Query: 974  VSPGQ----------QQASGAAVGGSSAGETRGAP--TPHEKALTSPSWGKGAELLLG-D 1020
            +S GQ           +A+G  +G  + G  +  P   P+++  T P  G    +  G  
Sbjct: 1246 MSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAP 1305

Query: 1021 QPDLIGS-LDGGAKSDSSSPNVGEFASDEVSTSYANE 1056
            QP+L+ S  D G  S S  P   +    +   SY N+
Sbjct: 1306 QPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQ 1342



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 130/561 (23%), Positives = 180/561 (32%), Gaps = 112/561 (19%)

Query: 661  PSLAPPPPPG------------------GSGVLFRGPLQEPMRMPGEGHVPALPSPGLQF 702
            P++ PP P G                  GSG    GP  EP      G+    P+     
Sbjct: 61   PAVGPPQPLGKELQDGAESNGGGGGGGAGSG---GGPGAEPDLKNSNGNAGPRPALNNNL 117

Query: 703  GGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALGGQPGFPFGAAG----RQSTPH 758
                GG G   S G G    SAA+   PP   F     G  P     AA     +Q    
Sbjct: 118  TEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFG-QPYGRSPSAVAAAAAAVFHQQHGGQ 176

Query: 759  SGPGVNSPPSAGGGGGSSGGG-------------------GGGGAYPPQPDFQPSQRTSA 799
              PG+ +  S GGGG     G                       AYPP     P+   S+
Sbjct: 177  QSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPP---APAYALSS 233

Query: 800  SKLG------ALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNP 853
             + G      A + GS   PSS       S  ++ S+  Q    ++G    +        
Sbjct: 234  PRGGTPGSGAAAAAGSKPPPSS-----SASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQ 288

Query: 854  PEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPG----GPSGTSSSGSKASGPPNP 909
            P     L+Q  T  ++  G  G   +PGG   G P  G    GP+  +S    A+     
Sbjct: 289  PTATPTLNQLLTSPSSARGYQG---YPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAA 345

Query: 910  PAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSG 969
             A   G +   ++    + G+     SGGGG+   R  + S   SP     K    P  G
Sbjct: 346  AAAASGGAQQRSHHAPMSPGS-----SGGGGQPLARTPQPS---SPMDQMGKMRPQP-YG 396

Query: 970  GAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSLD 1029
            G    S  Q   SG   G    G+  G+ TP    +T     + A               
Sbjct: 397  GTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAM-------------- 442

Query: 1030 GGAKSDSSSPNVGEFA----SDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLP 1085
            GG       P  G+        +  T Y N+      S +PQ      + P     P   
Sbjct: 443  GGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQ-----QSPHPQ----QQQPPYSQQPPSQT 493

Query: 1086 PRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAP 1145
            P    + +  P++ PP L        +S P        P H  +P     +  T+     
Sbjct: 494  PHAQPSYQQQPQSQPPQL-------QSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQ--- 543

Query: 1146 PPDEIHPLEILQAQIQLQRQQ 1166
             P    P    QAQ   Q+QQ
Sbjct: 544  HPQSQPPYSQPQAQSPYQQQQ 564



 Score = 57.4 bits (137), Expect = 9e-08
 Identities = 107/440 (24%), Positives = 143/440 (32%), Gaps = 72/440 (16%)

Query: 721  LPSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPP------------S 768
            L  A  ++R      A +A   + G    AAG++S    GP V  P             +
Sbjct: 24   LKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQES---EGPAVGPPQPLGKELQDGAESN 80

Query: 769  AGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAAL 828
             GGGGG +G GGG GA   +PD + S   +A    AL+      P       G      +
Sbjct: 81   GGGGGGGAGSGGGPGA---EPDLKNS-NGNAGPRPALNNNLTEPPGGG----GGGSSDGV 132

Query: 829  STACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAP 888
                 +  A+L  P           P G+   +      A      G    PG  A  + 
Sbjct: 133  GAPPHSAAAALPPPAYGF-----GQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSG 187

Query: 889  GPGG--PSGTSSSGSKASGPPNP------PAQGDGTSLSPNYTLESTSGNDGKPVSGGGG 940
            G GG  P       S   G PN       P +      +P Y L S  G  G P SG   
Sbjct: 188  GGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRG--GTPGSGAAA 245

Query: 941  RGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTP 1000
                +    S            SA+  S      S   QQ  GA  GG  +    G P P
Sbjct: 246  AAGSKPPPSS------------SASASSSS----SSFAQQRFGAMGGGGPSAAGGGTPQP 289

Query: 1001 H-----EKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYAN 1055
                   + LTSPS  +G +   G      G   GG +   +     + AS     + A 
Sbjct: 290  TATPTLNQLLTSPSSARGYQGYPG------GDYSGGPQDGGAGKGPADMASQCWGAAAAA 343

Query: 1056 EDEVSSSSDNPQALVKASRSPLVTGS-----PKLPPRGVGAGEHGPKAPPPALGLGIMSN 1110
                ++S    Q    A  SP  +G       + P       + G   P P  G    S 
Sbjct: 344  AAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQ 403

Query: 1111 STSTPDSYGGGGGPGHPGTP 1130
                P   G   G G+PG P
Sbjct: 404  QQGPPS--GPQQGHGYPGQP 421



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 85/329 (25%), Positives = 116/329 (35%), Gaps = 82/329 (24%)

Query: 853  PPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPAQ 912
            PP   +K  Q + + A            GG A  A         +++G ++ GP   P Q
Sbjct: 20   PPSELKKAEQQQREEA------------GGEAAAAAAAERGEMKAAAGQESEGPAVGPPQ 67

Query: 913  GDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAP 972
              G  L      ES  G  G    GG G G G          PG   D  ++  ++G  P
Sbjct: 68   PLGKELQDG--AESNGGGGG----GGAGSGGG----------PGAEPDLKNSNGNAGPRP 111

Query: 973  GVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLI------- 1025
             ++    +  G   GGSS G   GAP PH  A   P    G     G  P  +       
Sbjct: 112  ALNNNLTEPPGGGGGGSSDGV--GAP-PHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAV 168

Query: 1026 ---------------------GSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSD 1064
                                 G L+  A    +S + G F + + ++ Y N      S+ 
Sbjct: 169  FHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHG-FPNHQYNSYYPNR-----SAY 222

Query: 1065 NPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTS-TPDSYG--GG 1121
             P A   A  SP   G+P     G GA       PPP+      S+S+S     +G  GG
Sbjct: 223  PPPAPAYALSSPR-GGTP-----GSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGG 276

Query: 1122 GGPGHPG--------TPGLEQVRTPTSSS 1142
            GGP   G        TP L Q+ T  SS+
Sbjct: 277  GGPSAAGGGTPQPTATPTLNQLLTSPSSA 305



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 95/418 (22%), Positives = 135/418 (32%), Gaps = 88/418 (21%)

Query: 135  GYGGAAGGLGSQPPFAEGYEHMAESQG--PE---SFGPQRPGNLPDFHSSGASSHAVPAP 189
            G G  A G     P+   Y+ +    G  PE   S G  +P  +P    SG  S +   P
Sbjct: 1267 GLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPP 1326

Query: 190  CLPLDQSPNRAASFHGLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSP 249
                 Q   R  S+    S+ G+ S S  P + T         Y  P +   G       
Sbjct: 1327 -QQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGP----PA 1381

Query: 250  SDSEGQLPHYAAGRQVPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQ 309
               EG++                  ++P + G     +    P Q QP  QQQ  Q   Q
Sbjct: 1382 KRHEGEM-----------------YSVPYSTGQGQPQQQQLPPAQPQPASQQQAAQPSPQ 1424

Query: 310  HGVFFERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPP---PQQQPPQQPPQQQPPPPPG 366
              V+ +                G+ +P          P   PQ Q P Q  + +   PPG
Sbjct: 1425 QDVYNQ---------------YGNAYPATATAATERRPAGGPQNQFPFQFGRDRVSAPPG 1469

Query: 367  LLVRQNSCPPALPRPQQGEA-----GTPSGGLQD------------GGPMLPSQHA--QF 407
               +QN  P  +  P Q  A     GT   G  D              P  P+ H   + 
Sbjct: 1470 TNAQQNMPPQMMGGPIQASAEVAQQGTMWQGRNDMTYNYANRQSTGSAPQGPAYHGVNRT 1529

Query: 408  EYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRF-----DFP 462
            +  +H  + R+ H  S P    + PP    P+  +     PP  N    P          
Sbjct: 1530 DEMLH-TDQRANHEGSWPSHGTRQPP--YGPSAPVPPMTRPPPSNYQPPPSMQNHIPQVS 1586

Query: 463  GSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPG-----EFTPPVPDSFPSGPPLQHP 515
              A + R            ++N  SPS  P L       +  PPVP S  +  P+Q P
Sbjct: 1587 SPAPLPR-----------PMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQPP 1633



 Score = 44.3 bits (103), Expect = 8e-04
 Identities = 75/300 (25%), Positives = 97/300 (32%), Gaps = 61/300 (20%)

Query: 336  PLMQPPQQAPPPPQQQPPQQPPQQQP----------PPPPGLLVRQNSCPPALPRPQQGE 385
            P +QPP  A     Q P  Q PQ             PP P       S P +   P  G 
Sbjct: 1128 PKIQPPSPAGSGSMQGP--QTPQSTSSSMAEGGDLKPPTPA------STPHSQIPPLPGM 1179

Query: 386  AGTPSGGLQDG------------GPMLPSQHAQFEYPIHRLENR-SMHPYSEPVFSMQHP 432
            + + S G+QD               M P+   Q       +  R S  P  +P  SM+  
Sbjct: 1180 SRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKA 1239

Query: 433  PPQ-------QAPNQRL----QHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGA 481
            P         Q PN  +         P   NVA  PR  +P     DR  +  G    G 
Sbjct: 1240 PGSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEG- 1298

Query: 482  LDNHLSPSAYPGLPGEFTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQ 541
               ++S  A          P P+  PS P     +P     QQQQQQQQ+      Q   
Sbjct: 1299 ---NMSTGA----------PQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFST 1345

Query: 542  QQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQP 601
            Q              M +Q     QQQ  ++P     G P    +G +       G  QP
Sbjct: 1346 QGTPSGSPFPSQQTTMYQQ-----QQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQP 1400



 Score = 32.3 bits (72), Expect = 3.1
 Identities = 75/345 (21%), Positives = 107/345 (31%), Gaps = 78/345 (22%)

Query: 245  DMFSPSDSEGQLPHYAAGRQVPGGAFPGASA-MPRAAGMVGLSKMHAQPPQQQPQQQQQP 303
            D+F+ +DS+   P          G+  G       ++ M     +    P   P  Q  P
Sbjct: 1116 DIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPP 1175

Query: 304  QQQQQQHGVFFERFSGARKMPVGLEPSVGS-RHPLMQPPQQAPPPPQQQPPQQPPQQ--- 359
                            +R   VG++ +         Q      P P  QP          
Sbjct: 1176 LPGM------------SRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGR 1223

Query: 360  ---QPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQD-----GGPML------PSQHA 405
               +P   P   +R+   P + P    G+   P+GG+ D      GP L      P QH 
Sbjct: 1224 MSYEPNKDPYGSMRK--APGSDPFMSSGQG--PNGGMGDPYSRAAGPGLGNVAMGPRQHY 1279

Query: 406  QFEYPIHRLENR----------------SMHPYSEPVFSMQHP---PPQQAPNQRLQHFD 446
             +  P  R+                   ++ P S P   M  P   PPQQ   Q+ +H  
Sbjct: 1280 PYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMP-SNPDSGMYSPSRYPPQQQQQQQQRH-- 1336

Query: 447  APPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPP----- 501
               Y N     +F   G+       S   +M+     N+  P     + G + PP     
Sbjct: 1337 -DSYGN-----QFSTQGTPSGSPFPSQQTTMYQQQQQNYKRP-----MDGTYGPPAKRHE 1385

Query: 502  -----VPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQ 541
                 VP S   G P Q   P  Q     QQQ  Q   QQ    Q
Sbjct: 1386 GEMYSVPYSTGQGQPQQQQLPPAQPQPASQQQAAQPSPQQDVYNQ 1430



 Score = 32.0 bits (71), Expect = 4.0
 Identities = 20/59 (33%), Positives = 26/59 (44%), Gaps = 3/59 (5%)

Query: 1090 GAGEHGPKA-PPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPP 1147
            G    GP   PP  LG  +   + S  +  GGGGG G  G PG E     ++ +  P P
Sbjct: 55   GQESEGPAVGPPQPLGKELQDGAES--NGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRP 111


>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
          Length = 2068

 Score =  103 bits (256), Expect = 1e-21
 Identities = 288/1239 (23%), Positives = 401/1239 (32%), Gaps = 273/1239 (22%)

Query: 8    EPQVNSRNAGQGERNFNETGLSMNTHFKAPAFHTGGPPG-----PVDPAMSALGEPPILG 62
            EP + + N   G R       ++N +   P    GG        P   A +AL  PP  G
Sbjct: 97   EPDLKNSNGNAGPRP------ALNNNLTEPPGGGGGGSSDGVGAPPHSAAAAL-PPPAYG 149

Query: 63   MNMEPYG-------------FHARGHSELHAGGLQAQPVHGFFGGQQPHHGHPGSHHPH- 108
               +PYG             FH + H    + GL A    G  GG +P+ G   + H H 
Sbjct: 150  FG-QPYGRSPSAVAAAAAAVFHQQ-HGGQQSPGLAALQSGGG-GGLEPYAGPQQNSHDHG 206

Query: 109  ----QHHPHFGGNFGGPDPGASCLHGGRLLGY--GGAAGGLGSQPPFAEGYEHMAESQGP 162
                Q++ ++      P P  +        G    GAA   GS+PP +      + S   
Sbjct: 207  FPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSS---ASASSSS 263

Query: 163  ESFGPQRPGNLPDFHSSGASSHAVPAPCLP----LDQSPNRAASFHGLPSSSGSDSHSLE 218
             SF  QR G +     S A          P    L  SP+ A  + G P    S      
Sbjct: 264  SSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSG----- 318

Query: 219  PRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAAGRQVPGGAFPGASAMPR 278
                   G  D       G A  G  DM   S   G     AA     GGA   +   P 
Sbjct: 319  -------GPQD-------GGAGKGPADM--ASQCWGAAAAAAAAAAASGGAQQRSHHAPM 362

Query: 279  AAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRHPLM 338
            + G  G      QP  + PQ      Q                         +G   P  
Sbjct: 363  SPGSSGGG---GQPLARTPQPSSPMDQ-------------------------MGKMRP-- 392

Query: 339  QPPQQAPPPPQQQPPQQPPQQ---QPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQ- 394
            QP     P  QQQ P   PQQ    P  P G     +  P   P   QG A +  GGL  
Sbjct: 393  QPYGGTNPYSQQQGPPSGPQQGHGYPGQPYG-----SQTPQRYPMTMQGRAQSAMGGLSY 447

Query: 395  --------DGGPMLPSQHAQFEYPIHRLENRSMHPYSE-PVFSMQHPPPQQAPNQRLQHF 445
                      GP    Q  Q  Y       +S HP  + P +S Q  PP Q P+ +    
Sbjct: 448  TQQIPPYGQQGPSGYGQQGQTPY----YNQQSPHPQQQQPPYSQQ--PPSQTPHAQ---- 497

Query: 446  DAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDS 505
              P Y                                     P + P       PP    
Sbjct: 498  --PSYQQ----------------------------------QPQSQPPQLQSSQPPYSQQ 521

Query: 506  FPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMAS-- 563
             PS PP Q     + S Q   QQ  Q Q    Q Q Q   QQQQ +Q A   + Q A+  
Sbjct: 522  -PSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYP 580

Query: 564  RNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGAGRLGTFEQQAP 623
            + Q Q+ +Q   +Q   P            P   L+Q +F  +  S  +       Q+  
Sbjct: 581  QPQSQQSQQTAYSQQRFP------------PPQELSQDSFGSQASSAPSMTSSKGGQEDM 628

Query: 624  HLAQESAWFSGPHPPPG-DLLPRRMGG--------SGLPADCG---------------PH 659
            +L+ +S   S P      D LP    G        SG+ +  G               PH
Sbjct: 629  NLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPH 688

Query: 660  DPSL-APPPPPGGSGVLF----RGPLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQS 714
             P +  P P P GS         GPL  P  +PG    P  PS      G    +     
Sbjct: 689  LPGIRGPSPSPVGSPASVAQSRSGPL-SPAAVPGNQMPPRPPS------GQSDSIMHPSM 741

Query: 715  PGAGVGLPSAASERRPPPPDFATSALGGQPG---FPFGAAGRQSTPHSGPGVNSPPSAGG 771
              + +       +R P  P +++     QPG    P   +G Q   H+G G     S G 
Sbjct: 742  NQSSIAQDRGYMQRNPQMPQYSSP----QPGSALSPRQPSGGQI--HTGMGSYQQNSMGS 795

Query: 772  GGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTA 831
             G   G  G  G YP QP++      +    G    G  N   +   + GQ  +    T 
Sbjct: 796  YGPQGGQYGPQGGYPRQPNYNALPNANYPSAG--MAGGINPMGAGGQMHGQPGIPPYGTL 853

Query: 832  CQNMI--ASLG----APNL-----NVTFNKKNPPEGKRKLSQNETDGAAVAGN------P 874
                +  AS+G     PN+      V      PP G  + +Q       VA N      P
Sbjct: 854  PPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPP 913

Query: 875  GSDYFPGGTAPGAPGPGGPSGTS-SSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDG- 932
            G   +P     G  G G P G   +S +    P  PP    GT  + +  + ++    G 
Sbjct: 914  G---YPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGL 970

Query: 933  -----KPVSGGGGRGRGRRKRDS---GHVSPGTFFDKYSAAPDSGGAP----GVSPGQQQ 980
                  P +    +  G  K +S      S  T  +K +   + GG P     V      
Sbjct: 971  GDVKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKITKLYELGGEPERKMWVDRYLAF 1030

Query: 981  ASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQP--DLIGSLDGGAKSDSSS 1038
                A+G ++       P    +   S     G   +  ++   +L  +L+ G  S ++S
Sbjct: 1031 TEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNLNVGTSSSAAS 1090

Query: 1039 PNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKL-PPRGVGAGE-HGP 1096
                      +   YA E ++    D P  +  A+ S      PK+ PP   G+G   GP
Sbjct: 1091 ----SLKKQYIQCLYAFECKIERGEDPPPDIFAAADSK--KSQPKIQPPSPAGSGSMQGP 1144

Query: 1097 KAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQV 1135
            + P           STS+  + GG   P  P +    Q+
Sbjct: 1145 QTP----------QSTSSSMAEGGDLKPPTPASTPHSQI 1173



 Score = 85.5 bits (210), Expect = 3e-16
 Identities = 278/1302 (21%), Positives = 411/1302 (31%), Gaps = 271/1302 (20%)

Query: 3    GLDQFE-PQVNSRNAGQGERNFNETGLSMNTHFK-APAFHTGGPPG--PVDPAMSALGEP 58
            GL+ +  PQ NS + G     +N    + + +   APA+    P G  P   A +A G  
Sbjct: 191  GLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSK 250

Query: 59   PILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHGHPGSHHP----------- 107
            P       P    A   S   +    AQ   G  GG  P     G+  P           
Sbjct: 251  P-------PPSSSASASS---SSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLT 300

Query: 108  -------HQHHPHFGGNF-GGPDPGASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHMAES 159
                   +Q +P  GG++ GGP  G +      +      A    +    A G       
Sbjct: 301  SPSSARGYQGYP--GGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSH 358

Query: 160  QGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDSHSLE- 218
              P S G    G  P   +        P P  P+DQ        +G     G++ +S + 
Sbjct: 359  HAPMSPGSSGGGGQPLART--------PQPSSPMDQMGKMRPQPYG-----GTNPYSQQQ 405

Query: 219  -PRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAAG----RQVPGGAFPGA 273
             P     QG      + YPG+          P   +G+      G    +Q+P     G 
Sbjct: 406  GPPSGPQQG------HGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGP 459

Query: 274  SAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGS 333
            S   +       ++    P QQQP   QQP  Q                     +PS   
Sbjct: 460  SGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPH-----------------AQPSY-Q 501

Query: 334  RHPLMQPPQ-QAPPPPQQQPPQQPPQQQPPPP-PGLLVRQNSCPPALPRPQQGEAGTPSG 391
            + P  QPPQ Q+  PP  Q P QPP QQ P P P         P + P   Q +A +P  
Sbjct: 502  QQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQ 561

Query: 392  GLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYM 451
              Q   P   +   Q  YP  + +      YS+  F    PP + + +       + P M
Sbjct: 562  QQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFP---PPQELSQDSFGSQASSAPSM 618

Query: 452  NVAK------------RPRF--DFPGS---------------AGVDRCASWNGSMHNGAL 482
              +K            RP    D  GS                     +S  G   N A 
Sbjct: 619  TSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPA- 677

Query: 483  DNHLSPSAYPGLPGEFTP-PVP----------------------DSFPSGPP------LQ 513
             +  SP   P LPG   P P P                      +  P  PP      + 
Sbjct: 678  QSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIM 737

Query: 514  HPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQR---- 569
            HP+ +  S+ Q +   Q+  Q  Q    Q       ++ +   +   M S  Q       
Sbjct: 738  HPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYG 797

Query: 570  ------------LRQPNLAQL-----------GHPGDVGQGGLVHGGPVGGLAQPNFERE 606
                         RQPN   L           G    +G GG +HG P  G+  P     
Sbjct: 798  PQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQP--GIP-PYGTLP 854

Query: 607  GGSTGAGRLGTFEQQAPHLAQESAWF-SGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAP 665
             G      +G      P++A       SG  PPPG +  R+   + +      +     P
Sbjct: 855  PGRMSHASMGN-RPYGPNMANMPPQVGSGMCPPPGGM-NRKTQETAVAMHVAANSIQNRP 912

Query: 666  PP-------------PPGGSGVLFRGPLQEPMRMP-GEGHVPALPSPGLQFGGSLGGLGQ 711
            P              PP G G+     +  P   P   G   A  S G+     + GLG 
Sbjct: 913  PGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGLGD 972

Query: 712  LQSPGA------GVGLPSAASERRPPPPDFATSA-------LGGQPGFPFGAAGRQS-TP 757
            ++   A        G P   S+ +       T+        LGG+P          + T 
Sbjct: 973  VKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKITKLYELGGEPERKMWVDRYLAFTE 1032

Query: 758  HSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSK- 816
                G+ + P+ G                 +P        S  ++G L+  + NK   + 
Sbjct: 1033 EKAMGMTNLPAVGR----------------KPLDLYRLYVSVKEIGGLTQVNKNKKWREL 1076

Query: 817  -DNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPE----GKRKLSQNETDGAAVA 871
              NL   +  +A S+  +  I  L A    +   +  PP+       K SQ +    + A
Sbjct: 1077 ATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPA 1136

Query: 872  GNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGND 931
            G+               GP  P  TSSS ++      P       S  P     S S + 
Sbjct: 1137 GSGSMQ-----------GPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSV 1185

Query: 932  GKPVSGGGGRGRGRRKRDSGHVSPG--------TFFDKYSAAPDS----------GGAPG 973
            G   +   G     +KR+S   +PG            + S  P+           G  P 
Sbjct: 1186 GIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPF 1245

Query: 974  VSPGQ----------QQASGAAVGGSSAGETRGAP--TPHEKALTSPSWGKGAELLLG-D 1020
            +S GQ           +A+G  +G  + G  +  P   P+++  T P  G    +  G  
Sbjct: 1246 MSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAP 1305

Query: 1021 QPDLIGS-LDGGAKSDSSSPNVGEFASDEVSTSYANE---DEVSSSSDNPQALVKASRSP 1076
            QP+L+ S  D G  S S  P   +    +   SY N+       S S  P       +  
Sbjct: 1306 QPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQ 1365

Query: 1077 LVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSY 1118
                SP   PR +       K+P    G+ +       P S+
Sbjct: 1366 QQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASH 1407



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 130/561 (23%), Positives = 180/561 (32%), Gaps = 112/561 (19%)

Query: 661  PSLAPPPPPG------------------GSGVLFRGPLQEPMRMPGEGHVPALPSPGLQF 702
            P++ PP P G                  GSG    GP  EP      G+    P+     
Sbjct: 61   PAVGPPQPLGKELQDGAESNGGGGGGGAGSG---GGPGAEPDLKNSNGNAGPRPALNNNL 117

Query: 703  GGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALGGQPGFPFGAAG----RQSTPH 758
                GG G   S G G    SAA+   PP   F     G  P     AA     +Q    
Sbjct: 118  TEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFG-QPYGRSPSAVAAAAAAVFHQQHGGQ 176

Query: 759  SGPGVNSPPSAGGGGGSSGGG-------------------GGGGAYPPQPDFQPSQRTSA 799
              PG+ +  S GGGG     G                       AYPP     P+   S+
Sbjct: 177  QSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPP---APAYALSS 233

Query: 800  SKLG------ALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNP 853
             + G      A + GS   PSS       S  ++ S+  Q    ++G    +        
Sbjct: 234  PRGGTPGSGAAAAAGSKPPPSS-----SASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQ 288

Query: 854  PEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPG----GPSGTSSSGSKASGPPNP 909
            P     L+Q  T  ++  G  G   +PGG   G P  G    GP+  +S    A+     
Sbjct: 289  PTATPTLNQLLTSPSSARGYQG---YPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAA 345

Query: 910  PAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSG 969
             A   G +   ++    + G+     SGGGG+   R  + S   SP     K    P  G
Sbjct: 346  AAAASGGAQQRSHHAPMSPGS-----SGGGGQPLARTPQPS---SPMDQMGKMRPQP-YG 396

Query: 970  GAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSLD 1029
            G    S  Q   SG   G    G+  G+ TP    +T     + A               
Sbjct: 397  GTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAM-------------- 442

Query: 1030 GGAKSDSSSPNVGEFA----SDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLP 1085
            GG       P  G+        +  T Y N+      S +PQ      + P     P   
Sbjct: 443  GGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQ-----QSPHPQ----QQQPPYSQQPPSQT 493

Query: 1086 PRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAP 1145
            P    + +  P++ PP L        +S P        P H  +P     +  T+     
Sbjct: 494  PHAQPSYQQQPQSQPPQL-------QSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQ--- 543

Query: 1146 PPDEIHPLEILQAQIQLQRQQ 1166
             P    P    QAQ   Q+QQ
Sbjct: 544  HPQSQPPYSQPQAQSPYQQQQ 564



 Score = 57.4 bits (137), Expect = 9e-08
 Identities = 107/440 (24%), Positives = 143/440 (32%), Gaps = 72/440 (16%)

Query: 721  LPSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPP------------S 768
            L  A  ++R      A +A   + G    AAG++S    GP V  P             +
Sbjct: 24   LKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQES---EGPAVGPPQPLGKELQDGAESN 80

Query: 769  AGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAAL 828
             GGGGG +G GGG GA   +PD + S   +A    AL+      P       G      +
Sbjct: 81   GGGGGGGAGSGGGPGA---EPDLKNS-NGNAGPRPALNNNLTEPPGGG----GGGSSDGV 132

Query: 829  STACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAP 888
                 +  A+L  P           P G+   +      A      G    PG  A  + 
Sbjct: 133  GAPPHSAAAALPPPAYGF-----GQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSG 187

Query: 889  GPGG--PSGTSSSGSKASGPPNP------PAQGDGTSLSPNYTLESTSGNDGKPVSGGGG 940
            G GG  P       S   G PN       P +      +P Y L S  G  G P SG   
Sbjct: 188  GGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRG--GTPGSGAAA 245

Query: 941  RGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTP 1000
                +    S            SA+  S      S   QQ  GA  GG  +    G P P
Sbjct: 246  AAGSKPPPSS------------SASASSSS----SSFAQQRFGAMGGGGPSAAGGGTPQP 289

Query: 1001 H-----EKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYAN 1055
                   + LTSPS  +G +   G      G   GG +   +     + AS     + A 
Sbjct: 290  TATPTLNQLLTSPSSARGYQGYPG------GDYSGGPQDGGAGKGPADMASQCWGAAAAA 343

Query: 1056 EDEVSSSSDNPQALVKASRSPLVTGS-----PKLPPRGVGAGEHGPKAPPPALGLGIMSN 1110
                ++S    Q    A  SP  +G       + P       + G   P P  G    S 
Sbjct: 344  AAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQ 403

Query: 1111 STSTPDSYGGGGGPGHPGTP 1130
                P   G   G G+PG P
Sbjct: 404  QQGPPS--GPQQGHGYPGQP 421



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 85/329 (25%), Positives = 116/329 (35%), Gaps = 82/329 (24%)

Query: 853  PPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPAQ 912
            PP   +K  Q + + A            GG A  A         +++G ++ GP   P Q
Sbjct: 20   PPSELKKAEQQQREEA------------GGEAAAAAAAERGEMKAAAGQESEGPAVGPPQ 67

Query: 913  GDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAP 972
              G  L      ES  G  G    GG G G G          PG   D  ++  ++G  P
Sbjct: 68   PLGKELQDG--AESNGGGGG----GGAGSGGG----------PGAEPDLKNSNGNAGPRP 111

Query: 973  GVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLI------- 1025
             ++    +  G   GGSS G   GAP PH  A   P    G     G  P  +       
Sbjct: 112  ALNNNLTEPPGGGGGGSSDGV--GAP-PHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAV 168

Query: 1026 ---------------------GSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSD 1064
                                 G L+  A    +S + G F + + ++ Y N      S+ 
Sbjct: 169  FHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHG-FPNHQYNSYYPNR-----SAY 222

Query: 1065 NPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTS-TPDSYG--GG 1121
             P A   A  SP   G+P     G GA       PPP+      S+S+S     +G  GG
Sbjct: 223  PPPAPAYALSSPR-GGTP-----GSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGG 276

Query: 1122 GGPGHPG--------TPGLEQVRTPTSSS 1142
            GGP   G        TP L Q+ T  SS+
Sbjct: 277  GGPSAAGGGTPQPTATPTLNQLLTSPSSA 305



 Score = 32.0 bits (71), Expect = 4.0
 Identities = 20/59 (33%), Positives = 26/59 (44%), Gaps = 3/59 (5%)

Query: 1090 GAGEHGPKA-PPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPP 1147
            G    GP   PP  LG  +   + S  +  GGGGG G  G PG E     ++ +  P P
Sbjct: 55   GQESEGPAVGPPQPLGKELQDGAES--NGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRP 111


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
            sapiens]
          Length = 1487

 Score =  102 bits (253), Expect = 3e-21
 Identities = 288/1172 (24%), Positives = 360/1172 (30%), Gaps = 229/1172 (19%)

Query: 43   GPPGPVDPAMS--ALGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHG 100
            GPPGP          G+P   G    P    ARG       GL     H  + G     G
Sbjct: 243  GPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPG--TPGLPGVKGHRGYPGLDGAKG 300

Query: 101  HPGSHHPHQHHPHFGGNFGGPDP-GASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHMAES 159
              G+          G N G P P G   L G R  G  G AG  G     A G +     
Sbjct: 301  EAGAPGVKGESGSPGEN-GSPGPMGPRGLPGER--GRTGPAGAAG-----ARGNDGQPGP 352

Query: 160  QGPESFGPQRPGNLPDFHSS-GASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDSHSLE 218
             GP   GP  P   P F  + GA   A P       + P  A    G P + GS      
Sbjct: 353  AGPP--GPVGPAGGPGFPGAPGAKGEAGPTGA----RGPEGAQGPRGEPGTPGSPG---- 402

Query: 219  PRRVTNQGAVDSL-----EYNYPGEAPSGHFDMFSPSDSEGQLPHYAAGRQVPGGAFPGA 273
            P   +     D +         PG A +  F    P    G  P  A G   P     G 
Sbjct: 403  PAGASGNPGTDGIPGAKGSAGAPGIAGAPGFP--GPRGPPG--PQGATGPLGP----KGQ 454

Query: 274  SAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGS 333
            +  P  AG  G      +P    PQ    P  ++ + G        AR  P G+ P    
Sbjct: 455  TGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRG--------ARGEPGGVGP---- 502

Query: 334  RHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGL 393
                + PP +   P  +  P Q     P   PG    +     A P+   G+ G P    
Sbjct: 503  ----IGPPGERGAPGNRGFPGQDGLAGPKGAPG---ERGPSGLAGPKGANGDPGRP---- 551

Query: 394  QDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPP--QQAPNQR-LQHFDAPPY 450
              G P LP        P        + P   P    +  PP  Q A  Q  +  F  P  
Sbjct: 552  --GEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKG 609

Query: 451  MN--VAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSF-- 506
             N    K      PG+ G+      +G    GA      P+   G  GE   P P  F  
Sbjct: 610  ANGEPGKAGEKGLPGAPGLRGLPGKDGE--TGAAGPP-GPAGPAGERGEQGAPGPSGFQG 666

Query: 507  ---PSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMAS 563
               P GPP +   P  Q +  +                            A  ++     
Sbjct: 667  LPGPPGPPGEGGKPGDQGVPGEA--------------------------GAPGLVGPRGE 700

Query: 564  RNQQQRLRQPNLAQL-------GHPGDVG-QGGLVHGGPVGGLAQPNFEREGGSTGAGRL 615
            R        P    L       G PG  G +G     GP G    P  +   G  GA  +
Sbjct: 701  RGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGI 760

Query: 616  GTFEQQAPHLAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPHDPS--------LAPPP 667
                   P   +      GP   PG     + GG GL    GP  P+        + PP 
Sbjct: 761  A-----GPKGDRGDVGEKGPEGAPG-----KDGGRGLTGPIGPPGPAGANGEKGEVGPPG 810

Query: 668  PPGGSGVLFRGPLQEPMRMPGEGHVPALPSPGLQFG--GSLGGLGQLQSPGA-GVGLPSA 724
            P G +G       +     PG       P    Q G  G  G  GQ    GA G   PS 
Sbjct: 811  PAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSG 870

Query: 725  ASERRPPP----PDFATSALG--GQPGFPFGAAGRQSTPHSG--PGVNSPPSAGGGGGSS 776
            A   + P     P  A  A G  G  GFP GAAGR   P S   PG   PP   G  G  
Sbjct: 871  APGPQGPTGVTGPKGARGAQGPPGATGFP-GAAGRVGPPGSNGNPGPPGPPGPSGKDGPK 929

Query: 777  GGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMI 836
            G  G  G  PP    +P  +  A   G       + PS  +   G   LA      Q  I
Sbjct: 930  GARGDSG--PPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAG-----QRGI 982

Query: 837  ASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAP-GAPGPGGPSG 895
              L        F     P G+                PG    PG +   G PGP GP G
Sbjct: 983  VGLPGQRGERGFPGLPGPSGE----------------PGKQGAPGASGDRGPPGPVGPPG 1026

Query: 896  TSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSP 955
             +       GP   P +            E + G DG P   G    +G R       +P
Sbjct: 1027 LT-------GPAGEPGR------------EGSPGADGPPGRDGAAGVKGDRGETGAVGAP 1067

Query: 956  GTFFDKYSAAPDSGGAPGVS--PGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKG 1013
            G        AP   G+PG +   G+Q   G A          GA  P       PS   G
Sbjct: 1068 G--------APGPPGSPGPAGPTGKQGDRGEA----------GAQGP-----MGPSGPAG 1104

Query: 1014 AELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKAS 1073
            A  + G Q         G K ++  P           T           S +     + +
Sbjct: 1105 ARGIQGPQGPR------GDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGD-----QGA 1153

Query: 1074 RSPLVTGSPKLPPRGVGA-------GEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGH 1126
              P     P+ PP  VG        G  GP  PP   G    +     P + G  G PG 
Sbjct: 1154 SGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGP 1213

Query: 1127 PGTPGLEQVRTPTSSSGAPPPDEIHPLEILQA 1158
            PG PG++             PD   PL+ ++A
Sbjct: 1214 PG-PGIDMSAFAGLGPREKGPD---PLQYMRA 1241



 Score = 94.7 bits (234), Expect = 5e-19
 Identities = 188/723 (26%), Positives = 227/723 (31%), Gaps = 115/723 (15%)

Query: 577  QLGHPGDVG----QGGLVHGGPVGGLAQPNFEREGGSTGA----GRLGTFEQQAPHLAQE 628
            Q G PG  G    QG     GP G    P    E G  GA    G +G         A  
Sbjct: 454  QTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPG 513

Query: 629  SAWF------SGPHPPPGDLLPRRMGG-SGLPADCG-PHDPSLAPPPPPGGSGVLFR--- 677
            +  F      +GP   PG+  P  + G  G   D G P +P L     PG  G+  R   
Sbjct: 514  NRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGL-----PGARGLTGRPGD 568

Query: 678  -GPLQE--PMRMPGEGHVPALPSPG--------LQFGGSLGGLGQLQSPGAGVGLPSAAS 726
             GP  +  P   PGE   P  P P         + F G  G  G+    G   GLP A  
Sbjct: 569  AGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEK-GLPGAPG 627

Query: 727  ERRPPPPDFATSALGGQ-PGFPFGAAGRQSTPHSG-----PGVNSPPSAGGGGGSSGGGG 780
             R  P  D  T A G   P  P G  G Q  P        PG   PP  GG  G  G  G
Sbjct: 628  LRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPG 687

Query: 781  GGGAY----PPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMI 836
              GA     P      P +R S    G             D   G S  A    A Q   
Sbjct: 688  EAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGA-QGPP 746

Query: 837  ASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAP-GAPGPGGPSG 895
               G P          P   +  + +   +GA     PG D   G T P G PGP G +G
Sbjct: 747  GLQGMPGERGAAGIAGPKGDRGDVGEKGPEGA-----PGKDGGRGLTGPIGPPGPAGANG 801

Query: 896  TSSSGSKASGPPNP---------PAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRR 946
                     GPP P         P +   T            G DG+P    G +G   +
Sbjct: 802  EKGE----VGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQP-GAKGEQGEAGQ 856

Query: 947  KRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGA-----AVGGSSAGETRGAP--- 998
            K D+G   P       S AP   G  GV+ G + A GA     A G   A    G P   
Sbjct: 857  KGDAGAPGP----QGPSGAPGPQGPTGVT-GPKGARGAQGPPGATGFPGAAGRVGPPGSN 911

Query: 999  -TPHEKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANED 1057
              P       PS   G +   GD          G    +  P +   A          +D
Sbjct: 912  GNPGPPGPPGPSGKDGPKGARGDS---------GPPGRAGEPGLQGPAGPPGEKGEPGDD 962

Query: 1058 EVSSSSDNPQALVKASRSPLV--------TGSPKLP-----PRGVGA----GEHGPKAPP 1100
              S +   P     A +  +V         G P LP     P   GA    G+ GP  P 
Sbjct: 963  GPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPV 1022

Query: 1101 PALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAP----PPDEIHPLEIL 1156
               GL   +       S G  G PG  G  G++  R  T + GAP    PP    P    
Sbjct: 1023 GPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGP---- 1078

Query: 1157 QAQIQLQRQQFSISEDQPLGLKGGKKGECAVGASGAQNGDSELGSCCSEAVKSAMSTIDL 1216
                  Q  +       P+G  G        G  G +    E G      +K       L
Sbjct: 1079 AGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGL 1138

Query: 1217 DSL 1219
              L
Sbjct: 1139 QGL 1141



 Score = 81.3 bits (199), Expect = 6e-15
 Identities = 155/605 (25%), Positives = 189/605 (31%), Gaps = 109/605 (18%)

Query: 593  GPVGGLAQPNFERE--GGSTGAGRLGTFEQQAPHLAQESAWFSGPHPPPGDLLPRRMGGS 650
            GP G   +P   ++  G     G  G   +Q P   +      G   P G     R G  
Sbjct: 101  GPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRG-----RDGEP 155

Query: 651  GLPADCGPHDPSLAPPPPPG---------------GSGVLFRGPLQEPMRMPGEGHVPA- 694
            G P + GP  P   PP PPG                +G    G +Q PM   G    P  
Sbjct: 156  GTPGNPGPPGPP-GPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGP 214

Query: 695  LPSPGLQ-------------FGGSLGGLGQLQSPG-----AGVGLPSAASERRPPPPDFA 736
              +PG Q               G +G  G    PG        G P  A ER PP P  A
Sbjct: 215  AGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGA 274

Query: 737  TSALGGQPGFPFGAAGRQSTP--HSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPS 794
                 G PG P G  G +  P      G    P   G  GS G  G  G  P  P   P 
Sbjct: 275  -RGFPGTPGLP-GVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPG--PMGPRGLPG 330

Query: 795  QRTSASKLGALSLGSFN---KPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKK 851
            +R      GA      +    P+      G +              + GA         +
Sbjct: 331  ERGRTGPAGAAGARGNDGQPGPAGPPGPVGPA-------GGPGFPGAPGAKGEAGPTGAR 383

Query: 852  NPPEGKRKLSQNETDG----AAVAGNPGSDYFPGGT-APGAPGPGGPSGTSSSGSKASGP 906
             P   +    +  T G    A  +GNPG+D  PG   + GAPG  G  G         GP
Sbjct: 384  GPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPG----PRGP 439

Query: 907  PNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAP 966
            P P  QG    L P        G  G+P    G +G    K + G   P         AP
Sbjct: 440  PGP--QGATGPLGP-------KGQTGEP-GIAGFKGEQGPKGEPGPAGP-------QGAP 482

Query: 967  DSGGAPGVSPGQQQASGAAVGGSSAGETRGAP----TPHEKALTSPSWGKGAELLLGDQP 1022
               G  G    + +  G  VG       RGAP     P +  L  P    G     G   
Sbjct: 483  GPAGEEGKRGARGEPGG--VGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSG--- 537

Query: 1023 DLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSP 1082
             L G    GA  D   P        E     A           PQ  V  S +P   G P
Sbjct: 538  -LAG--PKGANGDPGRPG-------EPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRP 587

Query: 1083 KLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSS 1142
              P      G  G +  P  +G      +   P   G  G PG PG  GL      T ++
Sbjct: 588  GPP------GPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAA 641

Query: 1143 GAPPP 1147
            G P P
Sbjct: 642  GPPGP 646



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 85/320 (26%), Positives = 110/320 (34%), Gaps = 65/320 (20%)

Query: 883  TAPGAPGPGGPSGTSSSGSKASGPPNPPA-QGDGTSLSPNYTLESTSGNDGKPVSGGGGR 941
            TA G PGP G  G         GP  PP  QG      P        G  G P       
Sbjct: 95   TASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGD-RGDKGEKGAP------- 146

Query: 942  GRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPH 1001
              G R RD     PGT        P + G PG  PG     G  +GG+ A +  G     
Sbjct: 147  --GPRGRDG---EPGT--------PGNPGPPG-PPGPPGPPG--LGGNFAAQMAGGFD-- 188

Query: 1002 EKALTSPSWGKGAELLLGDQPDLIGSLDG-GAKSDSSSPNVGEFASDEVSTSYANEDEVS 1060
            EKA        GA+L +   P  +G +   G    + +P    F  +        E  VS
Sbjct: 189  EKA-------GGAQLGVMQGP--MGPMGPRGPPGPAGAPGPQGFQGNP---GEPGEPGVS 236

Query: 1061 SSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGG 1120
                 P+        P   G    P +   AGE GP  P  A G          P + G 
Sbjct: 237  GPM-GPRGPPGPPGKPGDDGEAGKPGK---AGERGPPGPQGARGF---------PGTPGL 283

Query: 1121 GGGPGHPGTPGLEQVRTPTSSSGAPPPDEIHPLEILQAQIQLQRQQFSISEDQPLGLKGG 1180
             G  GH G PGL+  +     +GAP          ++ +     +  S     P GL G 
Sbjct: 284  PGVKGHRGYPGLDGAK---GEAGAPG---------VKGESGSPGENGSPGPMGPRGLPGE 331

Query: 1181 KKGECAVGASGAQNGDSELG 1200
            +      GA+GA+  D + G
Sbjct: 332  RGRTGPAGAAGARGNDGQPG 351


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
            sapiens]
          Length = 1418

 Score =  102 bits (253), Expect = 3e-21
 Identities = 288/1172 (24%), Positives = 360/1172 (30%), Gaps = 229/1172 (19%)

Query: 43   GPPGPVDPAMS--ALGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHG 100
            GPPGP          G+P   G    P    ARG       GL     H  + G     G
Sbjct: 174  GPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPG--TPGLPGVKGHRGYPGLDGAKG 231

Query: 101  HPGSHHPHQHHPHFGGNFGGPDP-GASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHMAES 159
              G+          G N G P P G   L G R  G  G AG  G     A G +     
Sbjct: 232  EAGAPGVKGESGSPGEN-GSPGPMGPRGLPGER--GRTGPAGAAG-----ARGNDGQPGP 283

Query: 160  QGPESFGPQRPGNLPDFHSS-GASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDSHSLE 218
             GP   GP  P   P F  + GA   A P       + P  A    G P + GS      
Sbjct: 284  AGPP--GPVGPAGGPGFPGAPGAKGEAGPTGA----RGPEGAQGPRGEPGTPGSPG---- 333

Query: 219  PRRVTNQGAVDSL-----EYNYPGEAPSGHFDMFSPSDSEGQLPHYAAGRQVPGGAFPGA 273
            P   +     D +         PG A +  F    P    G  P  A G   P     G 
Sbjct: 334  PAGASGNPGTDGIPGAKGSAGAPGIAGAPGFP--GPRGPPG--PQGATGPLGP----KGQ 385

Query: 274  SAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGS 333
            +  P  AG  G      +P    PQ    P  ++ + G        AR  P G+ P    
Sbjct: 386  TGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRG--------ARGEPGGVGP---- 433

Query: 334  RHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGL 393
                + PP +   P  +  P Q     P   PG    +     A P+   G+ G P    
Sbjct: 434  ----IGPPGERGAPGNRGFPGQDGLAGPKGAPG---ERGPSGLAGPKGANGDPGRP---- 482

Query: 394  QDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPP--QQAPNQR-LQHFDAPPY 450
              G P LP        P        + P   P    +  PP  Q A  Q  +  F  P  
Sbjct: 483  --GEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKG 540

Query: 451  MN--VAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSF-- 506
             N    K      PG+ G+      +G    GA      P+   G  GE   P P  F  
Sbjct: 541  ANGEPGKAGEKGLPGAPGLRGLPGKDGE--TGAAGPP-GPAGPAGERGEQGAPGPSGFQG 597

Query: 507  ---PSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMAS 563
               P GPP +   P  Q +  +                            A  ++     
Sbjct: 598  LPGPPGPPGEGGKPGDQGVPGEA--------------------------GAPGLVGPRGE 631

Query: 564  RNQQQRLRQPNLAQL-------GHPGDVG-QGGLVHGGPVGGLAQPNFEREGGSTGAGRL 615
            R        P    L       G PG  G +G     GP G    P  +   G  GA  +
Sbjct: 632  RGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGI 691

Query: 616  GTFEQQAPHLAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPHDPS--------LAPPP 667
                   P   +      GP   PG     + GG GL    GP  P+        + PP 
Sbjct: 692  A-----GPKGDRGDVGEKGPEGAPG-----KDGGRGLTGPIGPPGPAGANGEKGEVGPPG 741

Query: 668  PPGGSGVLFRGPLQEPMRMPGEGHVPALPSPGLQFG--GSLGGLGQLQSPGA-GVGLPSA 724
            P G +G       +     PG       P    Q G  G  G  GQ    GA G   PS 
Sbjct: 742  PAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSG 801

Query: 725  ASERRPPP----PDFATSALG--GQPGFPFGAAGRQSTPHSG--PGVNSPPSAGGGGGSS 776
            A   + P     P  A  A G  G  GFP GAAGR   P S   PG   PP   G  G  
Sbjct: 802  APGPQGPTGVTGPKGARGAQGPPGATGFP-GAAGRVGPPGSNGNPGPPGPPGPSGKDGPK 860

Query: 777  GGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMI 836
            G  G  G  PP    +P  +  A   G       + PS  +   G   LA      Q  I
Sbjct: 861  GARGDSG--PPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAG-----QRGI 913

Query: 837  ASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAP-GAPGPGGPSG 895
              L        F     P G+                PG    PG +   G PGP GP G
Sbjct: 914  VGLPGQRGERGFPGLPGPSGE----------------PGKQGAPGASGDRGPPGPVGPPG 957

Query: 896  TSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSP 955
             +       GP   P +            E + G DG P   G    +G R       +P
Sbjct: 958  LT-------GPAGEPGR------------EGSPGADGPPGRDGAAGVKGDRGETGAVGAP 998

Query: 956  GTFFDKYSAAPDSGGAPGVS--PGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKG 1013
            G        AP   G+PG +   G+Q   G A          GA  P       PS   G
Sbjct: 999  G--------APGPPGSPGPAGPTGKQGDRGEA----------GAQGP-----MGPSGPAG 1035

Query: 1014 AELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKAS 1073
            A  + G Q         G K ++  P           T           S +     + +
Sbjct: 1036 ARGIQGPQGPR------GDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGD-----QGA 1084

Query: 1074 RSPLVTGSPKLPPRGVGA-------GEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGH 1126
              P     P+ PP  VG        G  GP  PP   G    +     P + G  G PG 
Sbjct: 1085 SGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGP 1144

Query: 1127 PGTPGLEQVRTPTSSSGAPPPDEIHPLEILQA 1158
            PG PG++             PD   PL+ ++A
Sbjct: 1145 PG-PGIDMSAFAGLGPREKGPD---PLQYMRA 1172



 Score = 94.7 bits (234), Expect = 5e-19
 Identities = 188/723 (26%), Positives = 227/723 (31%), Gaps = 115/723 (15%)

Query: 577  QLGHPGDVG----QGGLVHGGPVGGLAQPNFEREGGSTGA----GRLGTFEQQAPHLAQE 628
            Q G PG  G    QG     GP G    P    E G  GA    G +G         A  
Sbjct: 385  QTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPG 444

Query: 629  SAWF------SGPHPPPGDLLPRRMGG-SGLPADCG-PHDPSLAPPPPPGGSGVLFR--- 677
            +  F      +GP   PG+  P  + G  G   D G P +P L     PG  G+  R   
Sbjct: 445  NRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGL-----PGARGLTGRPGD 499

Query: 678  -GPLQE--PMRMPGEGHVPALPSPG--------LQFGGSLGGLGQLQSPGAGVGLPSAAS 726
             GP  +  P   PGE   P  P P         + F G  G  G+    G   GLP A  
Sbjct: 500  AGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEK-GLPGAPG 558

Query: 727  ERRPPPPDFATSALGGQ-PGFPFGAAGRQSTPHSG-----PGVNSPPSAGGGGGSSGGGG 780
             R  P  D  T A G   P  P G  G Q  P        PG   PP  GG  G  G  G
Sbjct: 559  LRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPG 618

Query: 781  GGGAY----PPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMI 836
              GA     P      P +R S    G             D   G S  A    A Q   
Sbjct: 619  EAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGA-QGPP 677

Query: 837  ASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAP-GAPGPGGPSG 895
               G P          P   +  + +   +GA     PG D   G T P G PGP G +G
Sbjct: 678  GLQGMPGERGAAGIAGPKGDRGDVGEKGPEGA-----PGKDGGRGLTGPIGPPGPAGANG 732

Query: 896  TSSSGSKASGPPNP---------PAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRR 946
                     GPP P         P +   T            G DG+P    G +G   +
Sbjct: 733  EKGE----VGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQP-GAKGEQGEAGQ 787

Query: 947  KRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGA-----AVGGSSAGETRGAP--- 998
            K D+G   P       S AP   G  GV+ G + A GA     A G   A    G P   
Sbjct: 788  KGDAGAPGP----QGPSGAPGPQGPTGVT-GPKGARGAQGPPGATGFPGAAGRVGPPGSN 842

Query: 999  -TPHEKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANED 1057
              P       PS   G +   GD          G    +  P +   A          +D
Sbjct: 843  GNPGPPGPPGPSGKDGPKGARGDS---------GPPGRAGEPGLQGPAGPPGEKGEPGDD 893

Query: 1058 EVSSSSDNPQALVKASRSPLV--------TGSPKLP-----PRGVGA----GEHGPKAPP 1100
              S +   P     A +  +V         G P LP     P   GA    G+ GP  P 
Sbjct: 894  GPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPV 953

Query: 1101 PALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAP----PPDEIHPLEIL 1156
               GL   +       S G  G PG  G  G++  R  T + GAP    PP    P    
Sbjct: 954  GPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGP---- 1009

Query: 1157 QAQIQLQRQQFSISEDQPLGLKGGKKGECAVGASGAQNGDSELGSCCSEAVKSAMSTIDL 1216
                  Q  +       P+G  G        G  G +    E G      +K       L
Sbjct: 1010 AGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGL 1069

Query: 1217 DSL 1219
              L
Sbjct: 1070 QGL 1072



 Score = 83.2 bits (204), Expect = 2e-15
 Identities = 165/635 (25%), Positives = 199/635 (31%), Gaps = 130/635 (20%)

Query: 564  RNQQQRLRQPN-LAQLGHPGDVGQ--GGLVHGGPVGGLAQPNFEREGGSTGAGRLGTFEQ 620
            R Q Q +RQP    Q G PGD+    G     GP G   +     + G  G       E+
Sbjct: 22   RCQGQDVRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKG-------EK 74

Query: 621  QAPHLAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPPPPG---------- 670
             AP          GP          R G  G P + GP  P   PP PPG          
Sbjct: 75   GAP----------GPRG--------RDGEPGTPGNPGPPGPP-GPPGPPGLGGNFAAQMA 115

Query: 671  -----GSGVLFRGPLQEPMRMPGEGHVPA-LPSPGLQ-------------FGGSLGGLGQ 711
                  +G    G +Q PM   G    P    +PG Q               G +G  G 
Sbjct: 116  GGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGP 175

Query: 712  LQSPG-----AGVGLPSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTP--HSGPGVN 764
               PG        G P  A ER PP P  A     G PG P G  G +  P      G  
Sbjct: 176  PGPPGKPGDDGEAGKPGKAGERGPPGPQGA-RGFPGTPGLP-GVKGHRGYPGLDGAKGEA 233

Query: 765  SPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFN---KPSSKDNLFG 821
              P   G  GS G  G  G  P  P   P +R      GA      +    P+      G
Sbjct: 234  GAPGVKGESGSPGENGSPG--PMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVG 291

Query: 822  QSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDG----AAVAGNPGSD 877
             +              + GA         + P   +    +  T G    A  +GNPG+D
Sbjct: 292  PA-------GGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTD 344

Query: 878  YFPGGT-APGAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVS 936
              PG   + GAPG  G  G         GPP P  QG    L P        G  G+P  
Sbjct: 345  GIPGAKGSAGAPGIAGAPGFPG----PRGPPGP--QGATGPLGP-------KGQTGEP-G 390

Query: 937  GGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRG 996
              G +G    K + G   P         AP   G  G    + +  G  VG       RG
Sbjct: 391  IAGFKGEQGPKGEPGPAGP-------QGAPGPAGEEGKRGARGEPGG--VGPIGPPGERG 441

Query: 997  AP----TPHEKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTS 1052
            AP     P +  L  P    G     G    L G    GA  D   P        E    
Sbjct: 442  APGNRGFPGQDGLAGPKGAPGERGPSG----LAG--PKGANGDPGRPG-------EPGLP 488

Query: 1053 YANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNST 1112
             A           PQ  V  S +P   G P  P      G  G +  P  +G      + 
Sbjct: 489  GARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPP------GPQGARGQPGVMGFPGPKGAN 542

Query: 1113 STPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPP 1147
              P   G  G PG PG  GL      T ++G P P
Sbjct: 543  GEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGP 577



 Score = 60.5 bits (145), Expect = 1e-08
 Identities = 110/459 (23%), Positives = 139/459 (30%), Gaps = 87/459 (18%)

Query: 712  LQSPGAGVGLPSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPPSAGG 771
            L+  G  V  P    ++  P          G PG P G AG Q  P    G      A G
Sbjct: 21   LRCQGQDVRQPGPKGQKGEPGDIKDIVGPKGPPG-PQGPAGEQG-PRGDRGDKGEKGAPG 78

Query: 772  GGGSSG-GGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALST 830
              G  G  G  G   PP P   P          A   G F++ +            A   
Sbjct: 79   PRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAG----------GAQLG 128

Query: 831  ACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTA-PGAPG 889
              Q  +  +G          + PP                AG PG   F G    PG PG
Sbjct: 129  VMQGPMGPMG---------PRGPP--------------GPAGAPGPQGFQGNPGEPGEPG 165

Query: 890  PGGPSGTSSSGSKASGPPNPPAQ-GDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKR 948
              GP G         GPP PP + GD          +  +G  GK    G    +G R  
Sbjct: 166  VSGPMG-------PRGPPGPPGKPGD----------DGEAGKPGKAGERGPPGPQGARGF 208

Query: 949  DSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSP 1008
                  PG    +     D       +PG +  SG+     S G       P E+  T P
Sbjct: 209  PGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGP 268

Query: 1009 SWGKGAELLLGD-----QPDLIGSLDG-------GAKSDSS-----SPNVGEFASDEVST 1051
            +   GA    G       P  +G   G       GAK ++       P   +    E  T
Sbjct: 269  AGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGT 328

Query: 1052 SYANEDEVSSSSDNPQALVKASRS---PLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIM 1108
              +     +S +     +  A  S   P + G+P  P      G  GP  P  A G    
Sbjct: 329  PGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFP------GPRGPPGPQGATGPLGP 382

Query: 1109 SNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPP 1147
               T  P   G  G  G  G PG      P    GAP P
Sbjct: 383  KGQTGEPGIAGFKGEQGPKGEPG------PAGPQGAPGP 415



 Score = 38.1 bits (87), Expect = 0.056
 Identities = 82/315 (26%), Positives = 107/315 (33%), Gaps = 65/315 (20%)

Query: 888  PGPGGPSGTSSSGSKASGPPNPPA-QGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRR 946
            PGP G  G         GP  PP  QG      P        G  G P         G R
Sbjct: 31   PGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGD-RGDKGEKGAP---------GPR 80

Query: 947  KRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALT 1006
             RD     PGT        P + G PG  PG     G  +GG+ A +  G     EKA  
Sbjct: 81   GRDG---EPGT--------PGNPGPPG-PPGPPGPPG--LGGNFAAQMAGGFD--EKA-- 122

Query: 1007 SPSWGKGAELLLGDQPDLIGSLDG-GAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDN 1065
                  GA+L +   P  +G +   G    + +P    F  +        E  VS     
Sbjct: 123  -----GGAQLGVMQGP--MGPMGPRGPPGPAGAPGPQGFQGNP---GEPGEPGVSGPM-G 171

Query: 1066 PQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPG 1125
            P+        P   G    P +   AGE GP  P  A G          P + G  G  G
Sbjct: 172  PRGPPGPPGKPGDDGEAGKPGK---AGERGPPGPQGARGF---------PGTPGLPGVKG 219

Query: 1126 HPGTPGLEQVRTPTSSSGAPPPDEIHPLEILQAQIQLQRQQFSISEDQPLGLKGGKKGEC 1185
            H G PGL+  +     +GAP          ++ +     +  S     P GL G +    
Sbjct: 220  HRGYPGLDGAK---GEAGAPG---------VKGESGSPGENGSPGPMGPRGLPGERGRTG 267

Query: 1186 AVGASGAQNGDSELG 1200
              GA+GA+  D + G
Sbjct: 268  PAGAAGARGNDGQPG 282


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
            sapiens]
          Length = 1650

 Score = 97.1 bits (240), Expect = 1e-19
 Identities = 152/603 (25%), Positives = 193/603 (32%), Gaps = 58/603 (9%)

Query: 571  RQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGA-GRLGTFEQQAPHLAQES 629
            RQ     LG PG  G  G      + G + P  ER  G TG  G+ G         A+ +
Sbjct: 720  RQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGER--GPTGPRGQRGPRGATGKSGAKGT 777

Query: 630  AWFSGPHPPPGDL-LPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPG 688
            +   GPH PPG+  LP   G +G P   GP       P PPG  G+      +  +   G
Sbjct: 778  SGGDGPHGPPGERGLPGPQGPNGFPGPKGP-------PGPPGKDGLPGHPGQRGEVGFQG 830

Query: 689  EGHVPALPSPGLQFG--GSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALGGQPGF 746
            +   P  P      G  G  G +G+   PG     P      +  P         G PG 
Sbjct: 831  KTGPPGPPGVVGPQGAAGETGPMGERGHPG-----PPGPPGEQGLPGTAGKEGTKGDPGP 885

Query: 747  PFGAAGRQSTP--HSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGA 804
            P GA G+         PG    P   GG G  G  G  G  PP P   P +R +A   G 
Sbjct: 886  P-GAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSG--PPGPAGSPGERGAAGSGGP 942

Query: 805  LSLGSFNKPSSKDNLFGQSCLAALS-----TACQNMIASLGAPNLNVTFNKKNPPEGKRK 859
            +       P       G+  +         T    +   +G P           P G   
Sbjct: 943  IGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPG----------PAGPPG 992

Query: 860  LSQNETDGAAVAGNPGSDYFPGGTAP-GAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSL 918
            ++  + D   V G+PG     G     G PGP GP G       A     P A+G     
Sbjct: 993  VAGEDGDKGEV-GDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHF 1051

Query: 919  SPNYTLESTSGNDGKPVSGG--GGRGRGRRKRDSGHVSP----GTFFDKYSAAPDSGGAP 972
                  E T G +G P   G  G  G    K ++G V P    G    +  A P+    P
Sbjct: 1052 GAKGD-EGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGP 1110

Query: 973  GVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIG--SLDG 1030
               PG     G        GE+       E  +  P   +G +   G QP   G     G
Sbjct: 1111 QGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESG-QPGEPGPPGPKG 1169

Query: 1031 GAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVG 1090
                D    N G              D        P+    A       G P  P     
Sbjct: 1170 PTGDDGPKGNPGPVGFPG--------DPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGP 1221

Query: 1091 AGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPPDEI 1150
             GE+GP  P    G      S       G  G PG  G PG      P   +G P PD +
Sbjct: 1222 TGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGL 1281

Query: 1151 HPL 1153
              L
Sbjct: 1282 RGL 1284



 Score = 87.4 bits (215), Expect = 8e-17
 Identities = 292/1162 (25%), Positives = 364/1162 (31%), Gaps = 265/1162 (22%)

Query: 43   GPPGPVDPAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHGHP 102
            GPPG       A G     GM  +P     RG   L   GL  +  H    G Q   G P
Sbjct: 443  GPPGKAGRRGRA-GADGARGMPGDPGVKGDRGFDGLP--GLPGEKGHRGDTGAQGLPGPP 499

Query: 103  GSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHMAESQGP 162
            G           G       PG S   G  LLG  G  G  G  PP   G   M   QGP
Sbjct: 500  GEDGERGDDGEIGPR---GLPGESGPRG--LLGPKGPPGIPG--PPGVRG---MDGPQGP 549

Query: 163  E-SFGPQ-RPGNLPDFHSSGASSHAVPAPCLPL----DQSPNRAASFHGLPSSSGSDSHS 216
            + S GPQ  PG  P        +  +P P   +    ++ P       G+P S G   H 
Sbjct: 550  KGSLGPQGEPG--PPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGH- 606

Query: 217  LEPRRVTNQGAVDSLEYNYPG-EAPSGHFDMFSPSDSEGQLPHYAAGRQVPGGAFPGASA 275
                               PG E P G      PS  +G L             +PG   
Sbjct: 607  -------------------PGKEGPPGTKGNQGPSGPQGPL------------GYPGPRG 635

Query: 276  MPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRH 335
            +    G+ GL K H              + ++ + G  F  F G     +G++   G R 
Sbjct: 636  VKGVDGIRGL-KGH--------------KGEKGEDG--FPGFKG----DIGVK---GDRG 671

Query: 336  PLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQD 395
             +  P  +    P+    +  P   P PP  +  +     P LP    G  G P G L  
Sbjct: 672  EVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPG-YPGRQG-PKGSL-- 727

Query: 396  GGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAK 455
            G P  P   A  E     L  +S             P  ++ P                 
Sbjct: 728  GFPGFPG--ASGEKGARGLSGKS------------GPRGERGPTG--------------- 758

Query: 456  RPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSFPS-----GP 510
             PR    G  G       +G+      D    P    GLPG   P  P+ FP      GP
Sbjct: 759  -PR----GQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPG---PQGPNGFPGPKGPPGP 810

Query: 511  PLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRL 570
            P +   P H          Q+ +   Q +            Q AA     M  R      
Sbjct: 811  PGKDGLPGHPG--------QRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPP 862

Query: 571  RQPNLAQLGHPGDVGQGGLVHG-GPVGGLAQPN------FEREGGSTG-AGRLGTFEQQA 622
              P   + G PG  G+ G     GP G   +        F  E G  G AG  G    + 
Sbjct: 863  GPPG--EQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEG 920

Query: 623  PHLAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPP--PPGGSGVLF---- 676
            P         SGP  P G    R   GSG     GP  P   P P  PPG +G       
Sbjct: 921  P---------SGPPGPAGSPGERGAAGSG-----GPIGPPGRPGPQGPPGAAGEKGVPGE 966

Query: 677  RGPL--------QEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASER 728
            +GP+        Q P+ +PG    PA P PG+   G  G  G++  PG   G      E 
Sbjct: 967  KGPIGPTGRDGVQGPVGLPG----PAGP-PGV--AGEDGDKGEVGDPGQK-GTKGNKGEH 1018

Query: 729  RPPPPDFATSALG--------GQPGFP-----FGAAGRQSTPHSGPGVNSPPSAGGGGGS 775
             PP P      +G        G+PG       FGA G + T     G N PP   G  G 
Sbjct: 1019 GPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTR----GFNGPPGPIGLQGL 1074

Query: 776  SGGGGG----GGAYPPQPDFQPSQRTSASKLGALS-------LGSFNKPSSKDNLFGQSC 824
             G  G     G   P  P   P  R  A   GA         +G+   P  K    G+S 
Sbjct: 1075 PGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEP-GESG 1133

Query: 825  LAALS--TACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGG 882
               +      +      G    +    +  PP  K       T      GNPG   FPG 
Sbjct: 1134 SPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPK-----GPTGDDGPKGNPGPVGFPGD 1188

Query: 883  TAPGAPGPGGPSGTSSS-GSKAS-GPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGG 940
              PG PG GGP G   + G +   G P  P     T  +         G  G P S G  
Sbjct: 1189 --PGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQ 1246

Query: 941  RGRGRRKRDSGHVSPGTFFDKYSAAPDSG-------GAPGVSPGQQQASGAAVGGSSAGE 993
             G+G +       +PG       A P          G PG S GQQ   GA      AG 
Sbjct: 1247 GGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPG-SVGQQGRPGAT---GQAGP 1302

Query: 994  TRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSL----DGGAKSDSSSPNVGEFASDEV 1049
                  P    L   +  KG +      P LIG +    + G K D   P          
Sbjct: 1303 PGPVGPPGLPGLRGDAGAKGEK----GHPGLIGLIGPPGEQGEKGDRGLPG--------- 1349

Query: 1050 STSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMS 1109
                       S     +  +  +  P+  G P   P     G  GPK    A G G   
Sbjct: 1350 --------PQGSPGQKGEMGIPGASGPIGPGGPPGLP-----GPAGPKGAKGATGPG--- 1393

Query: 1110 NSTSTPDSYGGGGGPGHPGTPG 1131
                     G  G PGHPG PG
Sbjct: 1394 ---GPKGEKGVQGPPGHPGPPG 1412



 Score = 87.0 bits (214), Expect = 1e-16
 Identities = 237/941 (25%), Positives = 301/941 (31%), Gaps = 176/941 (18%)

Query: 327  LEPSVGSRH-PLMQPPQQAPPPPQQQPP-------QQPPQQQPPPPPGLLVRQNSCPPAL 378
            LE   G R  P  Q P +A   PQQQP        Q+P  Q P P     + ++S  P L
Sbjct: 226  LECEGGQRERPQNQQPHRAQRSPQQQPSRLHRPQNQEPQSQDPTPGEEEEILESSLLPPL 285

Query: 379  ------PRPQQGEAGTPS---GGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSM 429
                  PR  +GE G P+    G+   GP  P   A    P     N    P  +P    
Sbjct: 286  EEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPG--PVGDP---G 340

Query: 430  QHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFPGSAGVDR---CASWNGSMHNGALDNHL 486
            +  PP +A          PP  ++    RF   GS G D+    A+             L
Sbjct: 341  ERGPPGRAGLPGSDGAPGPPGTSLMLPFRF---GSGGGDKGPVVAAQEAQAQAILQQARL 397

Query: 487  SPSAYPGLPGEFTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQ 546
            +    PG  G    P P   P  P L+  + D         Q  +  Q       +  ++
Sbjct: 398  ALRGPPGPMGYTGRPGPLGQPGSPGLKGESGD------LGPQGPRGPQGLTGPPGKAGRR 451

Query: 547  QQQQRQNAALMIKQMASRNQQQRLRQPNL-AQLGHPGDVGQGGLVHGGPVGGLAQPNFER 605
             +     A  M      +  +     P L  + GH GD G  GL   GP G   +   + 
Sbjct: 452  GRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGL--PGPPGEDGERGDDG 509

Query: 606  EGGSTG----AGRLGTFEQQAPHLAQES---AWFSGPHPPPGDLLPR----------RMG 648
            E G  G    +G  G    + P             GP  P G L P+            G
Sbjct: 510  EIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPG 569

Query: 649  GSGLPAD---CGPHD-------------PSLAPPP-------PPGGSGVLFRGPLQEPMR 685
              GLP      GPH              P    PP       PPG  G       Q P+ 
Sbjct: 570  TQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLG 629

Query: 686  MPG-------------EGHVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPP 732
             PG             +GH       G  F G  G +G ++     VG+P +  E  P  
Sbjct: 630  YPGPRGVKGVDGIRGLKGHKGEKGEDG--FPGFKGDIG-VKGDRGEVGVPGSRGEDGPEG 686

Query: 733  PDFATSALG--------------GQPGFPFGAAGRQSTPHS-----GPGVNSPPSAGGGG 773
            P   T   G              G PG P G  GRQ    S      PG +    A G  
Sbjct: 687  PKGRTGPTGDPGPPGLMGEKGKLGVPGLP-GYPGRQGPKGSLGFPGFPGASGEKGARGLS 745

Query: 774  GSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQ 833
            G SG  G  G  P  P  Q   R +  K GA      + P       G            
Sbjct: 746  GKSGPRGERG--PTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLP---------- 793

Query: 834  NMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSD---YFPGGTA-PGAPG 889
                  G    N     K PP    K      DG  + G+PG      F G T  PG PG
Sbjct: 794  ------GPQGPNGFPGPKGPPGPPGK------DG--LPGHPGQRGEVGFQGKTGPPGPPG 839

Query: 890  PGGPSG----TSSSGSKA-SGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRG 944
              GP G    T   G +   GPP PP +     L      E T G+ G P + G     G
Sbjct: 840  VVGPQGAAGETGPMGERGHPGPPGPPGE---QGLPGTAGKEGTKGDPGPPGAPGKDGPAG 896

Query: 945  RRKRDSGHVSPGTFFD---KYSAAPDSGGAPGVSPGQQQA--SGAAVGGSSAGETRGAP- 998
             R        PGT      K +  P     P  SPG++ A  SG  +G       +G P 
Sbjct: 897  LRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPG 956

Query: 999  ------TPHEKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTS 1052
                   P EK    P+   G +  +G  P   G   G A  D     VG+    +  T 
Sbjct: 957  AAGEKGVPGEKGPIGPTGRDGVQGPVG-LPGPAGP-PGVAGEDGDKGEVGD--PGQKGTK 1012

Query: 1053 YANEDEVSSSSDNPQALVKASRSPLVTGSP--KLPPRGVGA----GEHGPKAPPPALGLG 1106
                +        P   V    +    G P  + P    GA    G  G   PP  +GL 
Sbjct: 1013 GNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQ 1072

Query: 1107 IMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPP 1147
             +   +      G  G  G PG PG    R P   +GA  P
Sbjct: 1073 GLPGPSGEKGETGDVGPMGPPGPPG---PRGPAGPNGADGP 1110



 Score = 85.5 bits (210), Expect = 3e-16
 Identities = 159/615 (25%), Positives = 192/615 (31%), Gaps = 116/615 (18%)

Query: 579  GHPGDVG-QGGLVHGGPVGGLAQPNFEREGGSTG----AGRLGTFEQQAPHLAQESAWFS 633
            G PG VG QG     GP+G    P      G  G    AG+ GT     P  A      +
Sbjct: 836  GPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPA 895

Query: 634  GPHPPPGDL-LPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRG-PLQEPMRMPGEGH 691
            G    PG+  LP   GG GL  + GP  P   P   PG  G    G P+  P R   +G 
Sbjct: 896  GLRGFPGERGLPGTAGGPGLKGNEGPSGPP-GPAGSPGERGAAGSGGPIGPPGRPGPQGP 954

Query: 692  VPALPSPGLQFGGSLGGLGQLQSPGAG--VGLPSAASERRPPPPDFATSALGGQPGFPFG 749
              A    G+   G  G +G     G    VGLP  A     PP         G+ G P G
Sbjct: 955  PGAAGEKGVP--GEKGPIGPTGRDGVQGPVGLPGPAG----PPGVAGEDGDKGEVGDP-G 1007

Query: 750  AAGRQSTP--HSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDF----QPSQRTSASKLG 803
              G +     H  PG   P    G  G++G  G  GA  PQ  F        R      G
Sbjct: 1008 QKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPG 1067

Query: 804  ALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQN 863
             + L     PS +    G              +  +G P          PP  +     N
Sbjct: 1068 PIGLQGLPGPSGEKGETGD-------------VGPMGPPG---------PPGPRGPAGPN 1105

Query: 864  ETDGA-------------AVAGNPGSDYFPGGTA-PGAPGPGGPSGTSSSGSKAS--GPP 907
              DG                 G PG    PG    PG  GP G  G      +    GPP
Sbjct: 1106 GADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPP 1165

Query: 908  NP--PAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHV-------SPGTF 958
             P  P   DG   +P        G+ G P   GG RG+   K D G         SPG  
Sbjct: 1166 GPKGPTGDDGPKGNPGPV--GFPGDPGPP-GEGGPRGQDGAKGDRGEDGEPGQPGSPGPT 1222

Query: 959  FDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLL 1018
             +     P     P  SPG +   G   G  + G+      P +     P+   G     
Sbjct: 1223 GENGPPGPLGKRGPAGSPGSEGRQG---GKGAKGDPGAIGAPGKTGPVGPAGPAGKP--- 1276

Query: 1019 GDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLV 1078
               PD +  L G         +VG+                      P A  +A   P  
Sbjct: 1277 --GPDGLRGLPG---------SVGQ-------------------QGRPGATGQAG-PPGP 1305

Query: 1079 TGSPKLPPRGVGAGEHGPKAPPPALGL------GIMSNSTSTPDSYGGGGGPGHPGTPGL 1132
             G P LP     AG  G K  P  +GL               P   G  G  G  G PG 
Sbjct: 1306 VGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGA 1365

Query: 1133 EQVRTPTSSSGAPPP 1147
                 P    G P P
Sbjct: 1366 SGPIGPGGPPGLPGP 1380



 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 246/1018 (24%), Positives = 319/1018 (31%), Gaps = 205/1018 (20%)

Query: 82   GLQAQP-VHGFFGGQQPHHGHPGSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAA 140
            G+   P V G  G Q P     GS  P Q  P   G  G   PG   L G +     GA 
Sbjct: 533  GIPGPPGVRGMDGPQGPK----GSLGP-QGEPGPPGQQG--TPGTQGLPGPQ-----GAI 580

Query: 141  GGLGSQPPFAE-GYEHMAESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCL--PLDQSP 197
            G  G + P  + G   M  S GP    P  PG      + G    + P   L  P  +  
Sbjct: 581  GPHGEKGPQGKPGLPGMPGSDGP----PGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGV 636

Query: 198  NRAASFHGLPSSSGSDSHSLEPRRVTNQGAV-DSLEYNYPG----EAPSGHFDMFSPSDS 252
                   GL    G       P    + G   D  E   PG    + P G      P+  
Sbjct: 637  KGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGD 696

Query: 253  EGQ--------------LPHYAAGRQVPGGA-----FPGASAMPRAAGMVGLSKMHAQPP 293
             G               LP Y  GRQ P G+     FPGAS    A G+ G S    +  
Sbjct: 697  PGPPGLMGEKGKLGVPGLPGYP-GRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERG 755

Query: 294  QQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQP- 352
               P+ Q+ P+    + G            P G     G + P   P  + PP P  +  
Sbjct: 756  PTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDG 815

Query: 353  -PQQPPQQQ---------PPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPS 402
             P  P Q+          PP PPG++  Q +     P  ++G  G P    + G P    
Sbjct: 816  LPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAG 875

Query: 403  QHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFP 462
            +                        +   P P  AP +     D P  +         FP
Sbjct: 876  KEG----------------------TKGDPGPPGAPGK-----DGPAGLR-------GFP 901

Query: 463  GSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSFPSGPPLQHPA-PDHQS 521
            G  G+   A   G      L  +  PS  PG  G  +P    +  SG P+  P  P  Q 
Sbjct: 902  GERGLPGTAGGPG------LKGNEGPSGPPGPAG--SPGERGAAGSGGPIGPPGRPGPQG 953

Query: 522  LQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHP 581
                  ++    ++       +   Q             +A  +  +        ++G P
Sbjct: 954  PPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDK-------GEVGDP 1006

Query: 582  GDVGQGGLV--HG-----GPVGGLAQPNFEREGGSTGA-GRLGTFEQQAPHLAQESAWFS 633
            G  G  G    HG     GP+G + QP      G  GA G  G F  +     + +  F+
Sbjct: 1007 GQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGD---EGTRGFN 1063

Query: 634  GPHPPPG-DLLPRRMGGSGLPADCGPHDPSLAPPP--------------PPGGSGVLFRG 678
            GP  P G   LP   G  G   D GP  P   P P              PPGG G L  G
Sbjct: 1064 GPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNL--G 1121

Query: 679  PLQEPMRMPGEGHVPALPS-PGLQFG----GSLGGLGQLQSPGAG--------------- 718
            P  E    PGE   P +   PG++      G  G  GQ   PG                 
Sbjct: 1122 PPGEKGE-PGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNP 1180

Query: 719  -----VGLPSAASERRPPPPDFATSALG-----GQPGFP-----------FGAAGRQSTP 757
                  G P    E  P   D A    G     GQPG P            G  G   +P
Sbjct: 1181 GPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSP 1240

Query: 758  HS-----GPGVNSPPSAGGGGGSSGG-GGGGGAYPPQPDFQ---PSQRTSASKLGALSLG 808
             S     G G    P A G  G +G  G  G A  P PD     P       + GA    
Sbjct: 1241 GSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQA 1300

Query: 809  SFNKPSSKDNLFGQSCLAALS--TACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETD 866
                P     L G    A          +I  +G P        +  P  +    Q    
Sbjct: 1301 GPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEM 1360

Query: 867  GAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLES 926
            G   A  P     PGG  PG PGP GP G       A+GP  P  +           ++ 
Sbjct: 1361 GIPGASGPIG---PGGP-PGLPGPAGPKGAKG----ATGPGGPKGEKG---------VQG 1403

Query: 927  TSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGA 984
              G+ G P            K+    V       +  A P +GGAPG   G ++  G+
Sbjct: 1404 PPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIP-TGGAPGSPGGLEEIFGS 1460



 Score = 70.9 bits (172), Expect = 8e-12
 Identities = 175/740 (23%), Positives = 232/740 (31%), Gaps = 151/740 (20%)

Query: 510  PPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQ--- 566
            P  Q P    +S QQQ  +  + Q Q+ Q Q     ++++  +++ L   + A+      
Sbjct: 236  PQNQQPHRAQRSPQQQPSRLHRPQNQEPQSQDPTPGEEEEILESSLLPPLEEAAHGPRGL 295

Query: 567  -----QQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTG-AGRLGTFEQ 620
                 +  + +P +   G PG  G  GL+  GP G    P    + G  G  GR G    
Sbjct: 296  KGEKGEPAVLEPGMLVEGPPGPEGPAGLI--GPPGIQGNPGPVGDPGERGPPGRAGL--- 350

Query: 621  QAPHLAQESAWFSGPHPPPGD--LLPRRMGGSGLPADCGP-------------HDPSLAP 665
                         G   PPG   +LP R G  G   D GP                 LA 
Sbjct: 351  ---------PGSDGAPGPPGTSLMLPFRFGSGG--GDKGPVVAAQEAQAQAILQQARLAL 399

Query: 666  PPPPGGSGVLFR-GPLQEPMRMPGEGHVPALPSPGLQ-FGGSLGGLGQLQSPGAGVGLPS 723
              PPG  G   R GPL +P             SPGL+   G LG  G  + P    G P 
Sbjct: 400  RGPPGPMGYTGRPGPLGQP------------GSPGLKGESGDLGPQGP-RGPQGLTGPPG 446

Query: 724  AASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGGGG 783
             A  R     D A     G PG P G  G +       G +  P   G  G  G  G  G
Sbjct: 447  KAGRRGRAGADGAR----GMPGDP-GVKGDR-------GFDGLPGLPGEKGHRGDTGAQG 494

Query: 784  AYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPN 843
               P P  +  +R    ++G   L   + P     L G                  G P 
Sbjct: 495  L--PGPPGEDGERGDDGEIGPRGLPGESGPR---GLLGPK-------------GPPGIPG 536

Query: 844  LNVTFNKKNPPEGKRKLS-QNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGS- 901
                     P   K  L  Q E       G PG+   PG    GA GP G  G       
Sbjct: 537  PPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPG--PQGAIGPHGEKGPQGKPGL 594

Query: 902  ----KASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGG-----GGRGRGRRKRDSGH 952
                 + GPP  P +        N       G  G P   G     G RG    K + G 
Sbjct: 595  PGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGE 654

Query: 953  VSPGTFFDKYSAAPDSG--GAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSW 1010
                 F        D G  G PG S G+    G                   K  T P+ 
Sbjct: 655  DGFPGFKGDIGVKGDRGEVGVPG-SRGEDGPEG------------------PKGRTGPTG 695

Query: 1011 GKGAELLLGDQPDL-IGSLDG-----GAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSD 1064
              G   L+G++  L +  L G     G K     P     + ++ +   + +       +
Sbjct: 696  DPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKS--GPRGE 753

Query: 1065 NPQALVKASRSPL-VTGSPKLPPRGVGAGEHGP---KAPPPALGLGIMSNSTSTPDSYGG 1120
                  +  R P   TG         G G HGP   +  P   G          P   G 
Sbjct: 754  RGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGK 813

Query: 1121 GGGPGHPGTPGLEQVRTPTSSSGAPPPDEIHPLEILQAQIQLQRQQFSISEDQPLGLKG- 1179
             G PGHPG  G    +  T   G  PP  + P             Q +  E  P+G +G 
Sbjct: 814  DGLPGHPGQRGEVGFQGKTGPPG--PPGVVGP-------------QGAAGETGPMGERGH 858

Query: 1180 ----GKKGECAVGASGAQNG 1195
                G  GE  +  +  + G
Sbjct: 859  PGPPGPPGEQGLPGTAGKEG 878



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 97/381 (25%), Positives = 122/381 (32%), Gaps = 73/381 (19%)

Query: 37  PAFHTGGPPGPVDPAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQ 96
           P     GPPGP  PA   +G P I G N  P G            G +  P      G  
Sbjct: 307 PGMLVEGPPGPEGPA-GLIGPPGIQG-NPGPVG----------DPGERGPPGRAGLPGSD 354

Query: 97  PHHGHPGSHHPHQHHPHFGGNFGGPDPGA------SCLHGGRL--------LGYGGAAGG 142
              G PG+          GG   GP   A      + L   RL        +GY G  G 
Sbjct: 355 GAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGP 414

Query: 143 LGSQP--PFAEGYEHMAESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRA 200
           LG QP  P  +G       QGP   GPQ     P        + A  A  +P D      
Sbjct: 415 LG-QPGSPGLKGESGDLGPQGPR--GPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGD 471

Query: 201 ASFHGLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQL-PHY 259
             F GLP   G   H             D+     PG  P G          +G++ P  
Sbjct: 472 RGFDGLPGLPGEKGH-----------RGDTGAQGLPG--PPGE---DGERGDDGEIGPRG 515

Query: 260 AAGRQVPGGAF--PGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERF 317
             G   P G     G   +P   G+ G+           PQ +  P  QQ          
Sbjct: 516 LPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGT-------- 567

Query: 318 SGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPA 377
            G + +P G + ++G       P  +  P  +   P  P    PP  PG        PP 
Sbjct: 568 PGTQGLP-GPQGAIG-------PHGEKGPQGKPGLPGMPGSDGPPGHPG-----KEGPPG 614

Query: 378 LPRPQQGEAGTPSGGLQDGGP 398
             +  QG +G P G L   GP
Sbjct: 615 -TKGNQGPSG-PQGPLGYPGP 633



 Score = 32.0 bits (71), Expect = 4.0
 Identities = 44/157 (28%), Positives = 61/157 (38%), Gaps = 17/157 (10%)

Query: 1056 EDEVSSSSDNPQALVKASRSPLVTGSPK-----LPPRGVGAGEHGPKAPPPALGL-GIMS 1109
            E+E+  SS  P  L +A+  P      K     L P  +  G  GP+ P   +G  GI  
Sbjct: 273  EEEILESSLLPP-LEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQG 331

Query: 1110 NSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSS-------GAPPPDEIHPLEILQAQIQL 1162
            N     D  G  G PG  G PG +    P  +S       G+   D+   +   +AQ Q 
Sbjct: 332  NPGPVGDP-GERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQA 390

Query: 1163 QRQQFSISEDQPLGLKG--GKKGECAVGASGAQNGDS 1197
              QQ  ++   P G  G  G+ G      S    G+S
Sbjct: 391  ILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGES 427


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
            sapiens]
          Length = 1629

 Score = 97.1 bits (240), Expect = 1e-19
 Identities = 152/603 (25%), Positives = 193/603 (32%), Gaps = 58/603 (9%)

Query: 571  RQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGA-GRLGTFEQQAPHLAQES 629
            RQ     LG PG  G  G      + G + P  ER  G TG  G+ G         A+ +
Sbjct: 699  RQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGER--GPTGPRGQRGPRGATGKSGAKGT 756

Query: 630  AWFSGPHPPPGDL-LPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPG 688
            +   GPH PPG+  LP   G +G P   GP       P PPG  G+      +  +   G
Sbjct: 757  SGGDGPHGPPGERGLPGPQGPNGFPGPKGP-------PGPPGKDGLPGHPGQRGEVGFQG 809

Query: 689  EGHVPALPSPGLQFG--GSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALGGQPGF 746
            +   P  P      G  G  G +G+   PG     P      +  P         G PG 
Sbjct: 810  KTGPPGPPGVVGPQGAAGETGPMGERGHPG-----PPGPPGEQGLPGTAGKEGTKGDPGP 864

Query: 747  PFGAAGRQSTP--HSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGA 804
            P GA G+         PG    P   GG G  G  G  G  PP P   P +R +A   G 
Sbjct: 865  P-GAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSG--PPGPAGSPGERGAAGSGGP 921

Query: 805  LSLGSFNKPSSKDNLFGQSCLAALS-----TACQNMIASLGAPNLNVTFNKKNPPEGKRK 859
            +       P       G+  +         T    +   +G P           P G   
Sbjct: 922  IGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPG----------PAGPPG 971

Query: 860  LSQNETDGAAVAGNPGSDYFPGGTAP-GAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSL 918
            ++  + D   V G+PG     G     G PGP GP G       A     P A+G     
Sbjct: 972  VAGEDGDKGEV-GDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHF 1030

Query: 919  SPNYTLESTSGNDGKPVSGG--GGRGRGRRKRDSGHVSP----GTFFDKYSAAPDSGGAP 972
                  E T G +G P   G  G  G    K ++G V P    G    +  A P+    P
Sbjct: 1031 GAKGD-EGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGP 1089

Query: 973  GVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIG--SLDG 1030
               PG     G        GE+       E  +  P   +G +   G QP   G     G
Sbjct: 1090 QGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESG-QPGEPGPPGPKG 1148

Query: 1031 GAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVG 1090
                D    N G              D        P+    A       G P  P     
Sbjct: 1149 PTGDDGPKGNPGPVGFPG--------DPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGP 1200

Query: 1091 AGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPPDEI 1150
             GE+GP  P    G      S       G  G PG  G PG      P   +G P PD +
Sbjct: 1201 TGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGL 1260

Query: 1151 HPL 1153
              L
Sbjct: 1261 RGL 1263



 Score = 87.4 bits (215), Expect = 8e-17
 Identities = 292/1162 (25%), Positives = 364/1162 (31%), Gaps = 265/1162 (22%)

Query: 43   GPPGPVDPAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHGHP 102
            GPPG       A G     GM  +P     RG   L   GL  +  H    G Q   G P
Sbjct: 422  GPPGKAGRRGRA-GADGARGMPGDPGVKGDRGFDGLP--GLPGEKGHRGDTGAQGLPGPP 478

Query: 103  GSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHMAESQGP 162
            G           G       PG S   G  LLG  G  G  G  PP   G   M   QGP
Sbjct: 479  GEDGERGDDGEIGPR---GLPGESGPRG--LLGPKGPPGIPG--PPGVRG---MDGPQGP 528

Query: 163  E-SFGPQ-RPGNLPDFHSSGASSHAVPAPCLPL----DQSPNRAASFHGLPSSSGSDSHS 216
            + S GPQ  PG  P        +  +P P   +    ++ P       G+P S G   H 
Sbjct: 529  KGSLGPQGEPG--PPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGH- 585

Query: 217  LEPRRVTNQGAVDSLEYNYPG-EAPSGHFDMFSPSDSEGQLPHYAAGRQVPGGAFPGASA 275
                               PG E P G      PS  +G L             +PG   
Sbjct: 586  -------------------PGKEGPPGTKGNQGPSGPQGPL------------GYPGPRG 614

Query: 276  MPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRH 335
            +    G+ GL K H              + ++ + G  F  F G     +G++   G R 
Sbjct: 615  VKGVDGIRGL-KGH--------------KGEKGEDG--FPGFKG----DIGVK---GDRG 650

Query: 336  PLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQD 395
             +  P  +    P+    +  P   P PP  +  +     P LP    G  G P G L  
Sbjct: 651  EVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPG-YPGRQG-PKGSL-- 706

Query: 396  GGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAK 455
            G P  P   A  E     L  +S             P  ++ P                 
Sbjct: 707  GFPGFPG--ASGEKGARGLSGKS------------GPRGERGPTG--------------- 737

Query: 456  RPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSFPS-----GP 510
             PR    G  G       +G+      D    P    GLPG   P  P+ FP      GP
Sbjct: 738  -PR----GQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPG---PQGPNGFPGPKGPPGP 789

Query: 511  PLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRL 570
            P +   P H          Q+ +   Q +            Q AA     M  R      
Sbjct: 790  PGKDGLPGHPG--------QRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPP 841

Query: 571  RQPNLAQLGHPGDVGQGGLVHG-GPVGGLAQPN------FEREGGSTG-AGRLGTFEQQA 622
              P   + G PG  G+ G     GP G   +        F  E G  G AG  G    + 
Sbjct: 842  GPPG--EQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEG 899

Query: 623  PHLAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPP--PPGGSGVLF---- 676
            P         SGP  P G    R   GSG     GP  P   P P  PPG +G       
Sbjct: 900  P---------SGPPGPAGSPGERGAAGSG-----GPIGPPGRPGPQGPPGAAGEKGVPGE 945

Query: 677  RGPL--------QEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASER 728
            +GP+        Q P+ +PG    PA P PG+   G  G  G++  PG   G      E 
Sbjct: 946  KGPIGPTGRDGVQGPVGLPG----PAGP-PGV--AGEDGDKGEVGDPGQK-GTKGNKGEH 997

Query: 729  RPPPPDFATSALG--------GQPGFP-----FGAAGRQSTPHSGPGVNSPPSAGGGGGS 775
             PP P      +G        G+PG       FGA G + T     G N PP   G  G 
Sbjct: 998  GPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTR----GFNGPPGPIGLQGL 1053

Query: 776  SGGGGG----GGAYPPQPDFQPSQRTSASKLGALS-------LGSFNKPSSKDNLFGQSC 824
             G  G     G   P  P   P  R  A   GA         +G+   P  K    G+S 
Sbjct: 1054 PGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEP-GESG 1112

Query: 825  LAALS--TACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGG 882
               +      +      G    +    +  PP  K       T      GNPG   FPG 
Sbjct: 1113 SPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPK-----GPTGDDGPKGNPGPVGFPGD 1167

Query: 883  TAPGAPGPGGPSGTSSS-GSKAS-GPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGG 940
              PG PG GGP G   + G +   G P  P     T  +         G  G P S G  
Sbjct: 1168 --PGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQ 1225

Query: 941  RGRGRRKRDSGHVSPGTFFDKYSAAPDSG-------GAPGVSPGQQQASGAAVGGSSAGE 993
             G+G +       +PG       A P          G PG S GQQ   GA      AG 
Sbjct: 1226 GGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPG-SVGQQGRPGAT---GQAGP 1281

Query: 994  TRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSL----DGGAKSDSSSPNVGEFASDEV 1049
                  P    L   +  KG +      P LIG +    + G K D   P          
Sbjct: 1282 PGPVGPPGLPGLRGDAGAKGEK----GHPGLIGLIGPPGEQGEKGDRGLPG--------- 1328

Query: 1050 STSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMS 1109
                       S     +  +  +  P+  G P   P     G  GPK    A G G   
Sbjct: 1329 --------PQGSPGQKGEMGIPGASGPIGPGGPPGLP-----GPAGPKGAKGATGPG--- 1372

Query: 1110 NSTSTPDSYGGGGGPGHPGTPG 1131
                     G  G PGHPG PG
Sbjct: 1373 ---GPKGEKGVQGPPGHPGPPG 1391



 Score = 85.5 bits (210), Expect = 3e-16
 Identities = 159/615 (25%), Positives = 192/615 (31%), Gaps = 116/615 (18%)

Query: 579  GHPGDVG-QGGLVHGGPVGGLAQPNFEREGGSTG----AGRLGTFEQQAPHLAQESAWFS 633
            G PG VG QG     GP+G    P      G  G    AG+ GT     P  A      +
Sbjct: 815  GPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPA 874

Query: 634  GPHPPPGDL-LPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRG-PLQEPMRMPGEGH 691
            G    PG+  LP   GG GL  + GP  P   P   PG  G    G P+  P R   +G 
Sbjct: 875  GLRGFPGERGLPGTAGGPGLKGNEGPSGPP-GPAGSPGERGAAGSGGPIGPPGRPGPQGP 933

Query: 692  VPALPSPGLQFGGSLGGLGQLQSPGAG--VGLPSAASERRPPPPDFATSALGGQPGFPFG 749
              A    G+   G  G +G     G    VGLP  A     PP         G+ G P G
Sbjct: 934  PGAAGEKGVP--GEKGPIGPTGRDGVQGPVGLPGPAG----PPGVAGEDGDKGEVGDP-G 986

Query: 750  AAGRQSTP--HSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDF----QPSQRTSASKLG 803
              G +     H  PG   P    G  G++G  G  GA  PQ  F        R      G
Sbjct: 987  QKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPG 1046

Query: 804  ALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQN 863
             + L     PS +    G              +  +G P          PP  +     N
Sbjct: 1047 PIGLQGLPGPSGEKGETGD-------------VGPMGPPG---------PPGPRGPAGPN 1084

Query: 864  ETDGA-------------AVAGNPGSDYFPGGTA-PGAPGPGGPSGTSSSGSKAS--GPP 907
              DG                 G PG    PG    PG  GP G  G      +    GPP
Sbjct: 1085 GADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPP 1144

Query: 908  NP--PAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHV-------SPGTF 958
             P  P   DG   +P        G+ G P   GG RG+   K D G         SPG  
Sbjct: 1145 GPKGPTGDDGPKGNPGPV--GFPGDPGPP-GEGGPRGQDGAKGDRGEDGEPGQPGSPGPT 1201

Query: 959  FDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLL 1018
             +     P     P  SPG +   G   G  + G+      P +     P+   G     
Sbjct: 1202 GENGPPGPLGKRGPAGSPGSEGRQG---GKGAKGDPGAIGAPGKTGPVGPAGPAGKP--- 1255

Query: 1019 GDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLV 1078
               PD +  L G         +VG+                      P A  +A   P  
Sbjct: 1256 --GPDGLRGLPG---------SVGQ-------------------QGRPGATGQAG-PPGP 1284

Query: 1079 TGSPKLPPRGVGAGEHGPKAPPPALGL------GIMSNSTSTPDSYGGGGGPGHPGTPGL 1132
             G P LP     AG  G K  P  +GL               P   G  G  G  G PG 
Sbjct: 1285 VGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGA 1344

Query: 1133 EQVRTPTSSSGAPPP 1147
                 P    G P P
Sbjct: 1345 SGPIGPGGPPGLPGP 1359



 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 246/1018 (24%), Positives = 319/1018 (31%), Gaps = 205/1018 (20%)

Query: 82   GLQAQP-VHGFFGGQQPHHGHPGSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAA 140
            G+   P V G  G Q P     GS  P Q  P   G  G   PG   L G +     GA 
Sbjct: 512  GIPGPPGVRGMDGPQGPK----GSLGP-QGEPGPPGQQG--TPGTQGLPGPQ-----GAI 559

Query: 141  GGLGSQPPFAE-GYEHMAESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCL--PLDQSP 197
            G  G + P  + G   M  S GP    P  PG      + G    + P   L  P  +  
Sbjct: 560  GPHGEKGPQGKPGLPGMPGSDGP----PGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGV 615

Query: 198  NRAASFHGLPSSSGSDSHSLEPRRVTNQGAV-DSLEYNYPG----EAPSGHFDMFSPSDS 252
                   GL    G       P    + G   D  E   PG    + P G      P+  
Sbjct: 616  KGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGD 675

Query: 253  EGQ--------------LPHYAAGRQVPGGA-----FPGASAMPRAAGMVGLSKMHAQPP 293
             G               LP Y  GRQ P G+     FPGAS    A G+ G S    +  
Sbjct: 676  PGPPGLMGEKGKLGVPGLPGYP-GRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERG 734

Query: 294  QQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQP- 352
               P+ Q+ P+    + G            P G     G + P   P  + PP P  +  
Sbjct: 735  PTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDG 794

Query: 353  -PQQPPQQQ---------PPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPS 402
             P  P Q+          PP PPG++  Q +     P  ++G  G P    + G P    
Sbjct: 795  LPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAG 854

Query: 403  QHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFP 462
            +                        +   P P  AP +     D P  +         FP
Sbjct: 855  KEG----------------------TKGDPGPPGAPGK-----DGPAGLR-------GFP 880

Query: 463  GSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSFPSGPPLQHPA-PDHQS 521
            G  G+   A   G      L  +  PS  PG  G  +P    +  SG P+  P  P  Q 
Sbjct: 881  GERGLPGTAGGPG------LKGNEGPSGPPGPAG--SPGERGAAGSGGPIGPPGRPGPQG 932

Query: 522  LQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHP 581
                  ++    ++       +   Q             +A  +  +        ++G P
Sbjct: 933  PPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDK-------GEVGDP 985

Query: 582  GDVGQGGLV--HG-----GPVGGLAQPNFEREGGSTGA-GRLGTFEQQAPHLAQESAWFS 633
            G  G  G    HG     GP+G + QP      G  GA G  G F  +     + +  F+
Sbjct: 986  GQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGD---EGTRGFN 1042

Query: 634  GPHPPPG-DLLPRRMGGSGLPADCGPHDPSLAPPP--------------PPGGSGVLFRG 678
            GP  P G   LP   G  G   D GP  P   P P              PPGG G L  G
Sbjct: 1043 GPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNL--G 1100

Query: 679  PLQEPMRMPGEGHVPALPS-PGLQFG----GSLGGLGQLQSPGAG--------------- 718
            P  E    PGE   P +   PG++      G  G  GQ   PG                 
Sbjct: 1101 PPGEKGE-PGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNP 1159

Query: 719  -----VGLPSAASERRPPPPDFATSALG-----GQPGFP-----------FGAAGRQSTP 757
                  G P    E  P   D A    G     GQPG P            G  G   +P
Sbjct: 1160 GPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSP 1219

Query: 758  HS-----GPGVNSPPSAGGGGGSSGG-GGGGGAYPPQPDFQ---PSQRTSASKLGALSLG 808
             S     G G    P A G  G +G  G  G A  P PD     P       + GA    
Sbjct: 1220 GSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQA 1279

Query: 809  SFNKPSSKDNLFGQSCLAALS--TACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETD 866
                P     L G    A          +I  +G P        +  P  +    Q    
Sbjct: 1280 GPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEM 1339

Query: 867  GAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLES 926
            G   A  P     PGG  PG PGP GP G       A+GP  P  +           ++ 
Sbjct: 1340 GIPGASGPIG---PGGP-PGLPGPAGPKGAKG----ATGPGGPKGEKG---------VQG 1382

Query: 927  TSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGA 984
              G+ G P            K+    V       +  A P +GGAPG   G ++  G+
Sbjct: 1383 PPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIP-TGGAPGSPGGLEEIFGS 1439



 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 173/718 (24%), Positives = 225/718 (31%), Gaps = 143/718 (19%)

Query: 524  QQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHPGD 583
            Q QQ  + Q+  QQQ  +  + Q Q+ +  AA   + +     +  + +P +   G PG 
Sbjct: 237  QNQQPHRAQRSPQQQPSRLHRPQNQEPQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGP 296

Query: 584  VGQGGLVHGGPVGGLAQPNFEREGGSTG-AGRLGTFEQQAPHLAQESAWFSGPHPPPGD- 641
             G  GL+  GP G    P    + G  G  GR G                 G   PPG  
Sbjct: 297  EGPAGLI--GPPGIQGNPGPVGDPGERGPPGRAGL------------PGSDGAPGPPGTS 342

Query: 642  -LLPRRMGGSGLPADCGP-------------HDPSLAPPPPPGGSGVLFR-GPLQEPMRM 686
             +LP R G  G   D GP                 LA   PPG  G   R GPL +P   
Sbjct: 343  LMLPFRFGSGG--GDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQP--- 397

Query: 687  PGEGHVPALPSPGLQ-FGGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALGGQPG 745
                      SPGL+   G LG  G  + P    G P  A  R     D A     G PG
Sbjct: 398  ---------GSPGLKGESGDLGPQGP-RGPQGLTGPPGKAGRRGRAGADGAR----GMPG 443

Query: 746  FPFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGAL 805
             P G  G +       G +  P   G  G  G  G  G   P P  +  +R    ++G  
Sbjct: 444  DP-GVKGDR-------GFDGLPGLPGEKGHRGDTGAQGL--PGPPGEDGERGDDGEIGPR 493

Query: 806  SLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLS-QNE 864
             L   + P     L G                  G P          P   K  L  Q E
Sbjct: 494  GLPGESGPR---GLLGPK-------------GPPGIPGPPGVRGMDGPQGPKGSLGPQGE 537

Query: 865  TDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGS-----KASGPPNPPAQGDGTSLS 919
                   G PG+   PG    GA GP G  G            + GPP  P +       
Sbjct: 538  PGPPGQQGTPGTQGLPG--PQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTK 595

Query: 920  PNYTLESTSGNDGKPVSGG-----GGRGRGRRKRDSGHVSPGTFFDKYSAAPDSG--GAP 972
             N       G  G P   G     G RG    K + G      F        D G  G P
Sbjct: 596  GNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVP 655

Query: 973  GVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDL-IGSLDG- 1030
            G S G+    G                   K  T P+   G   L+G++  L +  L G 
Sbjct: 656  G-SRGEDGPEG------------------PKGRTGPTGDPGPPGLMGEKGKLGVPGLPGY 696

Query: 1031 ----GAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPL-VTGSPKLP 1085
                G K     P     + ++ +   + +       +      +  R P   TG     
Sbjct: 697  PGRQGPKGSLGFPGFPGASGEKGARGLSGKS--GPRGERGPTGPRGQRGPRGATGKSGAK 754

Query: 1086 PRGVGAGEHGP---KAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSS 1142
                G G HGP   +  P   G          P   G  G PGHPG  G    +  T   
Sbjct: 755  GTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPP 814

Query: 1143 GAPPPDEIHPLEILQAQIQLQRQQFSISEDQPLGLKG-----GKKGECAVGASGAQNG 1195
            G  PP  + P             Q +  E  P+G +G     G  GE  +  +  + G
Sbjct: 815  G--PPGVVGP-------------QGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEG 857



 Score = 74.3 bits (181), Expect = 7e-13
 Identities = 241/1005 (23%), Positives = 313/1005 (31%), Gaps = 193/1005 (19%)

Query: 293  PQQQPQQQQQPQQQQQQ----HGVFFERFSGARKMPVGLEPSV---GSRHPLMQPPQQAP 345
            PQQQP +  +PQ Q+ Q    HG       G +  P  LEP +   G   P        P
Sbjct: 248  PQQQPSRLHRPQNQEPQSQAAHGP--RGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGP 305

Query: 346  PPPQQQP-PQQPPQQQPPPPPGLLVRQNSCPPALPRPQQGEAGTP--------SGGLQDG 396
            P  Q  P P   P ++ PP    L   +  P        G  GT         SGG  D 
Sbjct: 306  PGIQGNPGPVGDPGERGPPGRAGLPGSDGAP--------GPPGTSLMLPFRFGSGG-GDK 356

Query: 397  GPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRL-------------- 442
            GP++ +Q AQ +  + +       P     ++ +  P  Q  +  L              
Sbjct: 357  GPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRG 416

Query: 443  -QHFDAPPYMNVAKRPRF------DFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLP 495
             Q    PP     +R R         PG  GV     ++G         H   +   GLP
Sbjct: 417  PQGLTGPP-GKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLP 475

Query: 496  GEFTPPVPDS-----------------------FPSGPPLQHPAPDHQSLQ-QQQQQQQQ 531
            G   PP  D                         P GPP     P  + +   Q  +   
Sbjct: 476  G---PPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSL 532

Query: 532  QQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNL----AQLGHPGDVG-- 585
              Q +     QQ     Q        I     +  Q +   P +       GHPG  G  
Sbjct: 533  GPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPP 592

Query: 586  -----------QGGLVHGGPVG--------GL----------AQPNFEREGGSTG----A 612
                       QG L + GP G        GL            P F+ + G  G     
Sbjct: 593  GTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEV 652

Query: 613  GRLGTFEQQAPHLAQESAWFSGPHPPPGDLLPR-RMGGSGLPADCGPHDP--SLAPPPPP 669
            G  G+  +  P   +     +G   PPG +  + ++G  GLP   G   P  SL  P  P
Sbjct: 653  GVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFP 712

Query: 670  GGSGVLFRGPLQEPMRMPGE----------GHVPALPSPGLQFGGSLGGLGQLQSPGAGV 719
            G SG      L       GE          G   A    G +  G+ GG G    PG   
Sbjct: 713  GASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAK--GTSGGDGPHGPPGER- 769

Query: 720  GLPSAASERRPPPPDFATSALG--GQPGFP--FGAAGRQ--STPHSGPGVNSPPSAGGGG 773
            GLP        P P       G  G PG P   G  G Q  + P   PGV  P  A G  
Sbjct: 770  GLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGET 829

Query: 774  GSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALS--TA 831
            G  G  G  G  PP P  +     +A K G  + G    P +     G+   A L     
Sbjct: 830  GPMGERGHPG--PPGPPGEQGLPGTAGKEG--TKGDPGPPGAP----GKDGPAGLRGFPG 881

Query: 832  CQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGA----AVAGNPGSDYFPGGT---- 883
             + +  + G P L        PP       +    G+       G PG    PG      
Sbjct: 882  ERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKG 941

Query: 884  APGAPGPGGPSGTSSSGSKAS--GPPNPPA----QGD-GTSLSPNYTLESTSGNDGK--- 933
             PG  GP GP+G           GP  PP      GD G    P    + T GN G+   
Sbjct: 942  VPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQ--KGTKGNKGEHGP 999

Query: 934  -----PVSGGGGRGRGRRKRDSGHVSP-GTFFDKYSAAPDSGGAPGVSPGQQQASGAAVG 987
                 P+   G  G      + G   P G F  K          P    G Q   G +  
Sbjct: 1000 PGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGE 1059

Query: 988  GSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSL----DGGAKSDSSSPNVGE 1043
                G+      P       P+   GA+   G  P  +G+L    + G   +S SP +  
Sbjct: 1060 KGETGDVGPMGPPGPPGPRGPAGPNGADGPQG-PPGGVGNLGPPGEKGEPGESGSPGIQ- 1117

Query: 1044 FASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVG-AGEHGPKAPPPA 1102
                 V        E   S    +      + P     PK  P  VG  G+ GP      
Sbjct: 1118 -GEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPP----- 1171

Query: 1103 LGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPP 1147
             G G            G  G PG PG+PG      PT  +G P P
Sbjct: 1172 -GEGGPRGQDGAKGDRGEDGEPGQPGSPG------PTGENGPPGP 1209



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 97/381 (25%), Positives = 122/381 (32%), Gaps = 73/381 (19%)

Query: 37  PAFHTGGPPGPVDPAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQ 96
           P     GPPGP  PA   +G P I G N  P G            G +  P      G  
Sbjct: 286 PGMLVEGPPGPEGPA-GLIGPPGIQG-NPGPVG----------DPGERGPPGRAGLPGSD 333

Query: 97  PHHGHPGSHHPHQHHPHFGGNFGGPDPGA------SCLHGGRL--------LGYGGAAGG 142
              G PG+          GG   GP   A      + L   RL        +GY G  G 
Sbjct: 334 GAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGP 393

Query: 143 LGSQP--PFAEGYEHMAESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRA 200
           LG QP  P  +G       QGP   GPQ     P        + A  A  +P D      
Sbjct: 394 LG-QPGSPGLKGESGDLGPQGPR--GPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGD 450

Query: 201 ASFHGLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQL-PHY 259
             F GLP   G   H             D+     PG  P G          +G++ P  
Sbjct: 451 RGFDGLPGLPGEKGH-----------RGDTGAQGLPG--PPGE---DGERGDDGEIGPRG 494

Query: 260 AAGRQVPGGAF--PGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERF 317
             G   P G     G   +P   G+ G+           PQ +  P  QQ          
Sbjct: 495 LPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGT-------- 546

Query: 318 SGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPA 377
            G + +P G + ++G       P  +  P  +   P  P    PP  PG        PP 
Sbjct: 547 PGTQGLP-GPQGAIG-------PHGEKGPQGKPGLPGMPGSDGPPGHPG-----KEGPPG 593

Query: 378 LPRPQQGEAGTPSGGLQDGGP 398
             +  QG +G P G L   GP
Sbjct: 594 -TKGNQGPSG-PQGPLGYPGP 612



 Score = 33.9 bits (76), Expect = 1.1
 Identities = 86/346 (24%), Positives = 110/346 (31%), Gaps = 44/346 (12%)

Query: 95  QQPHHGH-PGSHHPHQHHPHFGGNFGGPDPGASCLHGGRLL----GYGGAAGGLGSQPPF 149
           QQP   H P +  P     H      G     + L  G L+    G  G AG +G  PP 
Sbjct: 250 QQPSRLHRPQNQEPQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIG--PPG 307

Query: 150 AEGYEHMAESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSS 209
            +G        G    GP     LP   S GA      +  LP             + + 
Sbjct: 308 IQGNPGPVGDPGER--GPPGRAGLPG--SDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQ 363

Query: 210 SGSDSHSLEPRRVTNQGAVDSLEYN-------YPG----EAPSGHFDMFSPSDSEGQL-P 257
                  L+  R+  +G    + Y         PG    +  SG      P   +G   P
Sbjct: 364 EAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGP 423

Query: 258 HYAAGRQVPGGAFPGASAMPRAAGMVG---LSKMHAQPPQQQPQQQQQPQQQQQQHGVFF 314
              AGR+   GA  GA  MP   G+ G      +   P ++  +     Q      G   
Sbjct: 424 PGKAGRRGRAGA-DGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDG 482

Query: 315 ERFSGARKMPVGLEPSVGSRHPL--MQPPQQAPPP-------PQ--------QQPPQQPP 357
           ER       P GL    G R  L    PP    PP       PQ        Q  P  P 
Sbjct: 483 ERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPG 542

Query: 358 QQQPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPSQ 403
           QQ  P   GL   Q +  P   +  QG+ G P     DG P  P +
Sbjct: 543 QQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGK 588


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score = 97.1 bits (240), Expect = 1e-19
 Identities = 152/603 (25%), Positives = 193/603 (32%), Gaps = 58/603 (9%)

Query: 571  RQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGA-GRLGTFEQQAPHLAQES 629
            RQ     LG PG  G  G      + G + P  ER  G TG  G+ G         A+ +
Sbjct: 806  RQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGER--GPTGPRGQRGPRGATGKSGAKGT 863

Query: 630  AWFSGPHPPPGDL-LPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPG 688
            +   GPH PPG+  LP   G +G P   GP       P PPG  G+      +  +   G
Sbjct: 864  SGGDGPHGPPGERGLPGPQGPNGFPGPKGP-------PGPPGKDGLPGHPGQRGEVGFQG 916

Query: 689  EGHVPALPSPGLQFG--GSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALGGQPGF 746
            +   P  P      G  G  G +G+   PG     P      +  P         G PG 
Sbjct: 917  KTGPPGPPGVVGPQGAAGETGPMGERGHPG-----PPGPPGEQGLPGTAGKEGTKGDPGP 971

Query: 747  PFGAAGRQSTP--HSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGA 804
            P GA G+         PG    P   GG G  G  G  G  PP P   P +R +A   G 
Sbjct: 972  P-GAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSG--PPGPAGSPGERGAAGSGGP 1028

Query: 805  LSLGSFNKPSSKDNLFGQSCLAALS-----TACQNMIASLGAPNLNVTFNKKNPPEGKRK 859
            +       P       G+  +         T    +   +G P           P G   
Sbjct: 1029 IGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPG----------PAGPPG 1078

Query: 860  LSQNETDGAAVAGNPGSDYFPGGTAP-GAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSL 918
            ++  + D   V G+PG     G     G PGP GP G       A     P A+G     
Sbjct: 1079 VAGEDGDKGEV-GDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHF 1137

Query: 919  SPNYTLESTSGNDGKPVSGG--GGRGRGRRKRDSGHVSP----GTFFDKYSAAPDSGGAP 972
                  E T G +G P   G  G  G    K ++G V P    G    +  A P+    P
Sbjct: 1138 GAKGD-EGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGP 1196

Query: 973  GVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIG--SLDG 1030
               PG     G        GE+       E  +  P   +G +   G QP   G     G
Sbjct: 1197 QGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESG-QPGEPGPPGPKG 1255

Query: 1031 GAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVG 1090
                D    N G              D        P+    A       G P  P     
Sbjct: 1256 PTGDDGPKGNPGPVGFPG--------DPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGP 1307

Query: 1091 AGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPPDEI 1150
             GE+GP  P    G      S       G  G PG  G PG      P   +G P PD +
Sbjct: 1308 TGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGL 1367

Query: 1151 HPL 1153
              L
Sbjct: 1368 RGL 1370



 Score = 87.4 bits (215), Expect = 8e-17
 Identities = 292/1162 (25%), Positives = 364/1162 (31%), Gaps = 265/1162 (22%)

Query: 43   GPPGPVDPAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHGHP 102
            GPPG       A G     GM  +P     RG   L   GL  +  H    G Q   G P
Sbjct: 529  GPPGKAGRRGRA-GADGARGMPGDPGVKGDRGFDGLP--GLPGEKGHRGDTGAQGLPGPP 585

Query: 103  GSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHMAESQGP 162
            G           G       PG S   G  LLG  G  G  G  PP   G   M   QGP
Sbjct: 586  GEDGERGDDGEIGPR---GLPGESGPRG--LLGPKGPPGIPG--PPGVRG---MDGPQGP 635

Query: 163  E-SFGPQ-RPGNLPDFHSSGASSHAVPAPCLPL----DQSPNRAASFHGLPSSSGSDSHS 216
            + S GPQ  PG  P        +  +P P   +    ++ P       G+P S G   H 
Sbjct: 636  KGSLGPQGEPG--PPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGH- 692

Query: 217  LEPRRVTNQGAVDSLEYNYPG-EAPSGHFDMFSPSDSEGQLPHYAAGRQVPGGAFPGASA 275
                               PG E P G      PS  +G L             +PG   
Sbjct: 693  -------------------PGKEGPPGTKGNQGPSGPQGPL------------GYPGPRG 721

Query: 276  MPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRH 335
            +    G+ GL K H              + ++ + G  F  F G     +G++   G R 
Sbjct: 722  VKGVDGIRGL-KGH--------------KGEKGEDG--FPGFKG----DIGVK---GDRG 757

Query: 336  PLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQD 395
             +  P  +    P+    +  P   P PP  +  +     P LP    G  G P G L  
Sbjct: 758  EVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPG-YPGRQG-PKGSL-- 813

Query: 396  GGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAK 455
            G P  P   A  E     L  +S             P  ++ P                 
Sbjct: 814  GFPGFPG--ASGEKGARGLSGKS------------GPRGERGPTG--------------- 844

Query: 456  RPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSFPS-----GP 510
             PR    G  G       +G+      D    P    GLPG   P  P+ FP      GP
Sbjct: 845  -PR----GQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPG---PQGPNGFPGPKGPPGP 896

Query: 511  PLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRL 570
            P +   P H          Q+ +   Q +            Q AA     M  R      
Sbjct: 897  PGKDGLPGHPG--------QRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPP 948

Query: 571  RQPNLAQLGHPGDVGQGGLVHG-GPVGGLAQPN------FEREGGSTG-AGRLGTFEQQA 622
              P   + G PG  G+ G     GP G   +        F  E G  G AG  G    + 
Sbjct: 949  GPPG--EQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEG 1006

Query: 623  PHLAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPP--PPGGSGVLF---- 676
            P         SGP  P G    R   GSG     GP  P   P P  PPG +G       
Sbjct: 1007 P---------SGPPGPAGSPGERGAAGSG-----GPIGPPGRPGPQGPPGAAGEKGVPGE 1052

Query: 677  RGPL--------QEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASER 728
            +GP+        Q P+ +PG    PA P PG+   G  G  G++  PG   G      E 
Sbjct: 1053 KGPIGPTGRDGVQGPVGLPG----PAGP-PGV--AGEDGDKGEVGDPGQK-GTKGNKGEH 1104

Query: 729  RPPPPDFATSALG--------GQPGFP-----FGAAGRQSTPHSGPGVNSPPSAGGGGGS 775
             PP P      +G        G+PG       FGA G + T     G N PP   G  G 
Sbjct: 1105 GPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTR----GFNGPPGPIGLQGL 1160

Query: 776  SGGGGG----GGAYPPQPDFQPSQRTSASKLGALS-------LGSFNKPSSKDNLFGQSC 824
             G  G     G   P  P   P  R  A   GA         +G+   P  K    G+S 
Sbjct: 1161 PGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEP-GESG 1219

Query: 825  LAALS--TACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGG 882
               +      +      G    +    +  PP  K       T      GNPG   FPG 
Sbjct: 1220 SPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPK-----GPTGDDGPKGNPGPVGFPGD 1274

Query: 883  TAPGAPGPGGPSGTSSS-GSKAS-GPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGG 940
              PG PG GGP G   + G +   G P  P     T  +         G  G P S G  
Sbjct: 1275 --PGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQ 1332

Query: 941  RGRGRRKRDSGHVSPGTFFDKYSAAPDSG-------GAPGVSPGQQQASGAAVGGSSAGE 993
             G+G +       +PG       A P          G PG S GQQ   GA      AG 
Sbjct: 1333 GGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPG-SVGQQGRPGAT---GQAGP 1388

Query: 994  TRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSL----DGGAKSDSSSPNVGEFASDEV 1049
                  P    L   +  KG +      P LIG +    + G K D   P          
Sbjct: 1389 PGPVGPPGLPGLRGDAGAKGEK----GHPGLIGLIGPPGEQGEKGDRGLPG--------- 1435

Query: 1050 STSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMS 1109
                       S     +  +  +  P+  G P   P     G  GPK    A G G   
Sbjct: 1436 --------PQGSPGQKGEMGIPGASGPIGPGGPPGLP-----GPAGPKGAKGATGPG--- 1479

Query: 1110 NSTSTPDSYGGGGGPGHPGTPG 1131
                     G  G PGHPG PG
Sbjct: 1480 ---GPKGEKGVQGPPGHPGPPG 1498



 Score = 85.5 bits (210), Expect = 3e-16
 Identities = 159/615 (25%), Positives = 192/615 (31%), Gaps = 116/615 (18%)

Query: 579  GHPGDVG-QGGLVHGGPVGGLAQPNFEREGGSTG----AGRLGTFEQQAPHLAQESAWFS 633
            G PG VG QG     GP+G    P      G  G    AG+ GT     P  A      +
Sbjct: 922  GPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPA 981

Query: 634  GPHPPPGDL-LPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRG-PLQEPMRMPGEGH 691
            G    PG+  LP   GG GL  + GP  P   P   PG  G    G P+  P R   +G 
Sbjct: 982  GLRGFPGERGLPGTAGGPGLKGNEGPSGPP-GPAGSPGERGAAGSGGPIGPPGRPGPQGP 1040

Query: 692  VPALPSPGLQFGGSLGGLGQLQSPGAG--VGLPSAASERRPPPPDFATSALGGQPGFPFG 749
              A    G+   G  G +G     G    VGLP  A     PP         G+ G P G
Sbjct: 1041 PGAAGEKGVP--GEKGPIGPTGRDGVQGPVGLPGPAG----PPGVAGEDGDKGEVGDP-G 1093

Query: 750  AAGRQSTP--HSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDF----QPSQRTSASKLG 803
              G +     H  PG   P    G  G++G  G  GA  PQ  F        R      G
Sbjct: 1094 QKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPG 1153

Query: 804  ALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQN 863
             + L     PS +    G              +  +G P          PP  +     N
Sbjct: 1154 PIGLQGLPGPSGEKGETGD-------------VGPMGPPG---------PPGPRGPAGPN 1191

Query: 864  ETDGA-------------AVAGNPGSDYFPGGTA-PGAPGPGGPSGTSSSGSKAS--GPP 907
              DG                 G PG    PG    PG  GP G  G      +    GPP
Sbjct: 1192 GADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPP 1251

Query: 908  NP--PAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHV-------SPGTF 958
             P  P   DG   +P        G+ G P   GG RG+   K D G         SPG  
Sbjct: 1252 GPKGPTGDDGPKGNPGPV--GFPGDPGPP-GEGGPRGQDGAKGDRGEDGEPGQPGSPGPT 1308

Query: 959  FDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLL 1018
             +     P     P  SPG +   G   G  + G+      P +     P+   G     
Sbjct: 1309 GENGPPGPLGKRGPAGSPGSEGRQG---GKGAKGDPGAIGAPGKTGPVGPAGPAGKP--- 1362

Query: 1019 GDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLV 1078
               PD +  L G         +VG+                      P A  +A   P  
Sbjct: 1363 --GPDGLRGLPG---------SVGQ-------------------QGRPGATGQAG-PPGP 1391

Query: 1079 TGSPKLPPRGVGAGEHGPKAPPPALGL------GIMSNSTSTPDSYGGGGGPGHPGTPGL 1132
             G P LP     AG  G K  P  +GL               P   G  G  G  G PG 
Sbjct: 1392 VGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGA 1451

Query: 1133 EQVRTPTSSSGAPPP 1147
                 P    G P P
Sbjct: 1452 SGPIGPGGPPGLPGP 1466



 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 246/1018 (24%), Positives = 319/1018 (31%), Gaps = 205/1018 (20%)

Query: 82   GLQAQP-VHGFFGGQQPHHGHPGSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAA 140
            G+   P V G  G Q P     GS  P Q  P   G  G   PG   L G +     GA 
Sbjct: 619  GIPGPPGVRGMDGPQGPK----GSLGP-QGEPGPPGQQG--TPGTQGLPGPQ-----GAI 666

Query: 141  GGLGSQPPFAE-GYEHMAESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCL--PLDQSP 197
            G  G + P  + G   M  S GP    P  PG      + G    + P   L  P  +  
Sbjct: 667  GPHGEKGPQGKPGLPGMPGSDGP----PGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGV 722

Query: 198  NRAASFHGLPSSSGSDSHSLEPRRVTNQGAV-DSLEYNYPG----EAPSGHFDMFSPSDS 252
                   GL    G       P    + G   D  E   PG    + P G      P+  
Sbjct: 723  KGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGD 782

Query: 253  EGQ--------------LPHYAAGRQVPGGA-----FPGASAMPRAAGMVGLSKMHAQPP 293
             G               LP Y  GRQ P G+     FPGAS    A G+ G S    +  
Sbjct: 783  PGPPGLMGEKGKLGVPGLPGYP-GRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERG 841

Query: 294  QQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQP- 352
               P+ Q+ P+    + G            P G     G + P   P  + PP P  +  
Sbjct: 842  PTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDG 901

Query: 353  -PQQPPQQQ---------PPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPS 402
             P  P Q+          PP PPG++  Q +     P  ++G  G P    + G P    
Sbjct: 902  LPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAG 961

Query: 403  QHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFP 462
            +                        +   P P  AP +     D P  +         FP
Sbjct: 962  KEG----------------------TKGDPGPPGAPGK-----DGPAGLR-------GFP 987

Query: 463  GSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSFPSGPPLQHPA-PDHQS 521
            G  G+   A   G      L  +  PS  PG  G  +P    +  SG P+  P  P  Q 
Sbjct: 988  GERGLPGTAGGPG------LKGNEGPSGPPGPAG--SPGERGAAGSGGPIGPPGRPGPQG 1039

Query: 522  LQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHP 581
                  ++    ++       +   Q             +A  +  +        ++G P
Sbjct: 1040 PPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDK-------GEVGDP 1092

Query: 582  GDVGQGGLV--HG-----GPVGGLAQPNFEREGGSTGA-GRLGTFEQQAPHLAQESAWFS 633
            G  G  G    HG     GP+G + QP      G  GA G  G F  +     + +  F+
Sbjct: 1093 GQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGD---EGTRGFN 1149

Query: 634  GPHPPPG-DLLPRRMGGSGLPADCGPHDPSLAPPP--------------PPGGSGVLFRG 678
            GP  P G   LP   G  G   D GP  P   P P              PPGG G L  G
Sbjct: 1150 GPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNL--G 1207

Query: 679  PLQEPMRMPGEGHVPALPS-PGLQFG----GSLGGLGQLQSPGAG--------------- 718
            P  E    PGE   P +   PG++      G  G  GQ   PG                 
Sbjct: 1208 PPGEKGE-PGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNP 1266

Query: 719  -----VGLPSAASERRPPPPDFATSALG-----GQPGFP-----------FGAAGRQSTP 757
                  G P    E  P   D A    G     GQPG P            G  G   +P
Sbjct: 1267 GPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSP 1326

Query: 758  HS-----GPGVNSPPSAGGGGGSSGG-GGGGGAYPPQPDFQ---PSQRTSASKLGALSLG 808
             S     G G    P A G  G +G  G  G A  P PD     P       + GA    
Sbjct: 1327 GSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQA 1386

Query: 809  SFNKPSSKDNLFGQSCLAALS--TACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETD 866
                P     L G    A          +I  +G P        +  P  +    Q    
Sbjct: 1387 GPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEM 1446

Query: 867  GAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLES 926
            G   A  P     PGG  PG PGP GP G       A+GP  P  +           ++ 
Sbjct: 1447 GIPGASGPIG---PGGP-PGLPGPAGPKGAKG----ATGPGGPKGEKG---------VQG 1489

Query: 927  TSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGA 984
              G+ G P            K+    V       +  A P +GGAPG   G ++  G+
Sbjct: 1490 PPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIP-TGGAPGSPGGLEEIFGS 1546



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 91/381 (23%), Positives = 128/381 (33%), Gaps = 71/381 (18%)

Query: 868  AAVAGNPGSDYFPGGTA-PGAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLES 926
            A + G PG    PG    PG  GP G +G   S     G P PP    GTSL   +   S
Sbjct: 407  AGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGS----DGAPGPP----GTSLMLPFRFGS 458

Query: 927  TSGNDGKPVSGGGGRGRG--RRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGA 984
              G+ G  V+    + +   ++ R +    PG     Y+  P   G PG SPG +  SG 
Sbjct: 459  GGGDKGPVVAAQEAQAQAILQQARLALRGPPGPM--GYTGRPGPLGQPG-SPGLKGESGD 515

Query: 985  AVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGS--LDGGAKSDSSSPNVG 1042
                   G       P +      +   GA  + GD P + G    DG         + G
Sbjct: 516  LGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGD-PGVKGDRGFDGLPGLPGEKGHRG 574

Query: 1043 EFASDEVSTSYANEDEVSSSSD----------NPQALVKASRSPLVTGSPKL-------- 1084
            +  +  +      + E     +           P+ L+     P + G P +        
Sbjct: 575  DTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQG 634

Query: 1085 ------------PPRGVGA-------------GEHGPKAPPPALGLGIMSNSTSTPDSYG 1119
                        PP   G              G HG K P    GL  M  S   P   G
Sbjct: 635  PKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPP---G 691

Query: 1120 GGGGPGHPGTPGLEQVRTPTSSSGAPPPDEIHPLEILQAQIQLQRQQFSISEDQPLGLKG 1179
              G  G PGT G +    P    G P P  +  ++ ++    L+  +    ED   G KG
Sbjct: 692  HPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRG---LKGHKGEKGEDGFPGFKG 748

Query: 1180 -----GKKGECAVGASGAQNG 1195
                 G +GE  V  S  ++G
Sbjct: 749  DIGVKGDRGEVGVPGSRGEDG 769



 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 147/688 (21%), Positives = 206/688 (29%), Gaps = 150/688 (21%)

Query: 519  HQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQL 578
            ++S +Q++ + +  Q+++ Q QQ  + Q+  Q+Q + L       R Q Q  +      L
Sbjct: 218  YESCEQKELECEGGQRERPQNQQPHRAQRSPQQQPSRL------HRPQNQEPQSQPTESL 271

Query: 579  GHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGAGRLGTFEQQAPHLAQESAWFSGPHPP 638
             +  +     ++  G       P    E     +  L   E++   L           PP
Sbjct: 272  YYDYEPPYYDVMTTGTTPDYQDPTPGEEEEILESSLLPPLEEEQTDLQV---------PP 322

Query: 639  PGDLLP-RRMGGSGLPADCGPHD----------------PSLAPPPPPGGSGVLFRGPLQ 681
              D       G  G     GP+D                P+L+      G+         
Sbjct: 323  TADRFQAEEYGEGGTDPPEGPYDYTYGYGDDYREETELGPALSAETAHSGAAA------H 376

Query: 682  EPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALG 741
             P  + GE   PA+  PG+   G  G  G    P   +G P                 + 
Sbjct: 377  GPRGLKGEKGEPAVLEPGMLVEGPPGPEG----PAGLIGPPG----------------IQ 416

Query: 742  GQPGFPFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGG--------------GGGGGAYPP 787
            G PG           P   PG   PP   G  GS G               G GGG   P
Sbjct: 417  GNPG-----------PVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGP 465

Query: 788  QPDFQPSQRTSASKLGALSLGSFNKP---SSKDNLFGQSCLAALSTACQNMIASLGAPNL 844
                Q +Q  +  +   L+L     P   + +    GQ      S   +     LG    
Sbjct: 466  VVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPG----SPGLKGESGDLGPQGP 521

Query: 845  NVTFNKKNPPEGKRKLSQNETDGA-------AVAGNPGSDYFPGGTAPGAPGPGGPSGTS 897
                    PP    +  +   DGA        V G+ G D  PG   PG  G  G +G  
Sbjct: 522  RGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPG--LPGEKGHRGDTG-- 577

Query: 898  SSGSKASGPPNPPAQ----GDGTSLSPNYTLESTS-----GNDGKPVSGG--GGRGRGRR 946
                 A G P PP +    GD   + P      +      G  G P   G  G RG    
Sbjct: 578  -----AQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGP 632

Query: 947  KRDSGHVSPGTFFDKYSAAPDSGGAPGVS--PGQQQASG--AAVGGSSAGETRGAP---- 998
            +   G + P          P   G PG    PG Q A G     G        G P    
Sbjct: 633  QGPKGSLGP----QGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDG 688

Query: 999  TPHEKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYAN-ED 1057
             P       P   KG +   G Q  L      G K       +     ++    +   + 
Sbjct: 689  PPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKG 748

Query: 1058 EVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDS 1117
            ++    D  +  V  SR                 GE GP+ P    G    +     P  
Sbjct: 749  DIGVKGDRGEVGVPGSR-----------------GEDGPEGPKGRTG---PTGDPGPPGL 788

Query: 1118 YGGGGGPGHPGTPGLEQVRTPTSSSGAP 1145
             G  G  G PG PG    + P  S G P
Sbjct: 789  MGEKGKLGVPGLPGYPGRQGPKGSLGFP 816



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 97/381 (25%), Positives = 122/381 (32%), Gaps = 73/381 (19%)

Query: 37  PAFHTGGPPGPVDPAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQ 96
           P     GPPGP  PA   +G P I G N  P G            G +  P      G  
Sbjct: 393 PGMLVEGPPGPEGPA-GLIGPPGIQG-NPGPVG----------DPGERGPPGRAGLPGSD 440

Query: 97  PHHGHPGSHHPHQHHPHFGGNFGGPDPGA------SCLHGGRL--------LGYGGAAGG 142
              G PG+          GG   GP   A      + L   RL        +GY G  G 
Sbjct: 441 GAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGP 500

Query: 143 LGSQP--PFAEGYEHMAESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRA 200
           LG QP  P  +G       QGP   GPQ     P        + A  A  +P D      
Sbjct: 501 LG-QPGSPGLKGESGDLGPQGPR--GPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGD 557

Query: 201 ASFHGLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQL-PHY 259
             F GLP   G   H             D+     PG  P G          +G++ P  
Sbjct: 558 RGFDGLPGLPGEKGH-----------RGDTGAQGLPG--PPGE---DGERGDDGEIGPRG 601

Query: 260 AAGRQVPGGAF--PGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERF 317
             G   P G     G   +P   G+ G+           PQ +  P  QQ          
Sbjct: 602 LPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGT-------- 653

Query: 318 SGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPA 377
            G + +P G + ++G       P  +  P  +   P  P    PP  PG        PP 
Sbjct: 654 PGTQGLP-GPQGAIG-------PHGEKGPQGKPGLPGMPGSDGPPGHPG-----KEGPPG 700

Query: 378 LPRPQQGEAGTPSGGLQDGGP 398
             +  QG +G P G L   GP
Sbjct: 701 -TKGNQGPSG-PQGPLGYPGP 719



 Score = 31.2 bits (69), Expect = 6.9
 Identities = 39/147 (26%), Positives = 56/147 (38%), Gaps = 16/147 (10%)

Query: 1061 SSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGL-GIMSNSTSTPDSYG 1119
            +++  P+ L      P V     L P  +  G  GP+ P   +G  GI  N     D  G
Sbjct: 373  AAAHGPRGLKGEKGEPAV-----LEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDP-G 426

Query: 1120 GGGGPGHPGTPGLEQVRTPTSSS-------GAPPPDEIHPLEILQAQIQLQRQQFSISED 1172
              G PG  G PG +    P  +S       G+   D+   +   +AQ Q   QQ  ++  
Sbjct: 427  ERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALR 486

Query: 1173 QPLGLKG--GKKGECAVGASGAQNGDS 1197
             P G  G  G+ G      S    G+S
Sbjct: 487  GPPGPMGYTGRPGPLGQPGSPGLKGES 513


>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3
           [Homo sapiens]
          Length = 2178

 Score = 96.7 bits (239), Expect = 1e-19
 Identities = 232/980 (23%), Positives = 316/980 (32%), Gaps = 236/980 (24%)

Query: 44  PPGPVDPAMSALGE----PPILGMNMEPYGFHARGHSELHAGGLQAQPV----------- 88
           PPGP  P +S  G+    PP +G   EP G     H  L A G Q  PV           
Sbjct: 115 PPGP--PLLSKPGDEDDAPPKMG---EPAGGRYE-HPGLGALGTQQPPVAVPGGGGGPAA 168

Query: 89  ----HGFFGGQQPHHGHPGSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLG 144
               + ++G   P  G PG     +  P F  + G   PG   +H         AAG  G
Sbjct: 169 VPEFNNYYGSAAPASGGPGG----RAGPCFDQHGGQQSPGMGMMHSAS----AAAAGAPG 220

Query: 145 SQPPFAEGYEHMAESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFH 204
           S  P    +E    SQ     G  RPG        G                 +      
Sbjct: 221 SMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGG------------SGGGGGG 268

Query: 205 GLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAAGRQ 264
           G   + G+ + ++         A         G + +G+  + SP             RQ
Sbjct: 269 GGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSP-------------RQ 315

Query: 265 VPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMP 324
             GG   G    P   G   LSK  A                       F+RF+G  + P
Sbjct: 316 QGGGMMMG----PGGGGAASLSKAAAGSAAGG-----------------FQRFAGQNQHP 354

Query: 325 VGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQG 384
            G  P++     L+  P    P  +      P    P  PP         PP+ P+ Q  
Sbjct: 355 SGATPTLNQ---LLTSPS---PMMRSYGGSYPEYSSPSAPPP--------PPSQPQSQAA 400

Query: 385 EAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQH 444
            AG  +GG Q    M   +    +Y        +    S P  S   P P    +Q    
Sbjct: 401 AAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQ---- 456

Query: 445 FDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSP---SAYPGLPGEFTPP 501
             +P    V KRP+    GS                  + H  P   S YPG  G + PP
Sbjct: 457 -GSPMDPMVMKRPQLYGMGS------------------NPHSQPQQSSPYPG--GSYGPP 495

Query: 502 VPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQ------QQQQQQQQQQQQQRQNAA 555
            P  +P G  +Q   P   +  Q  QQQ   Q  QQ      QQ QQ    QQ Q  +  
Sbjct: 496 GPQRYPIG--IQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLP 553

Query: 556 LMIKQMASRNQQQRLRQPNLAQLGH---------PGDVGQ-----------------GGL 589
              + + S++QQ+   Q +++Q G+         PG                      G 
Sbjct: 554 PQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGS 613

Query: 590 VHGGPVGGLAQ-PNFEREGGSTGAGRLGTFEQQAPHLAQESAWFS----GPHPPP-GDLL 643
           +   P G  A   +     GST +    +   Q+P     S   S    GP P P G  +
Sbjct: 614 IDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPV 673

Query: 644 PRRMGGSGLPADCGPHDPSLAPPPPPGGSG------VLFRGPL-QEPMRMPGEGHVPAL- 695
                 SG P        S  PP PPG          L + P+ QE   M G    P + 
Sbjct: 674 GSNQSRSG-PISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMA 732

Query: 696 --------------PSPGLQFGGSL-------------------GGLGQLQSPGAGVGLP 722
                         PSPG Q    +                   G  G    P A  G+P
Sbjct: 733 QYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVP 792

Query: 723 SAASERRPPPPDFATSA---LGGQ-PGFPFGA--------AGRQSTPHSGPGVNSPPSAG 770
           SA+     P P    SA   + GQ P  P GA        AG Q+ P  G   +  PS+ 
Sbjct: 793 SASYS--GPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSP 850

Query: 771 GGGGSSGGGGGGGAYPPQPDF-QPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALS 829
           G     G G G    PP P   + +Q  +A+ + A +  + ++  S   +     +A+ S
Sbjct: 851 GMSQQGGPGMG----PPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSS 906

Query: 830 TACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETD---GAAVAGNPGSDYFP-----G 881
              Q M       N +   N + PP        N +    G A   +PG    P      
Sbjct: 907 PYSQPM------NNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKAD 960

Query: 882 GTAPGAPGPGGPSGTSSSGS 901
           G   G P P   S  SSS +
Sbjct: 961 GKEEGTPQPESKSKKSSSST 980



 Score = 95.1 bits (235), Expect = 4e-19
 Identities = 168/663 (25%), Positives = 217/663 (32%), Gaps = 145/663 (21%)

Query: 514  HPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQP 573
            H    H +LQQQ  Q QQQQQQQQQQQQQQQQQQ     N +L                 
Sbjct: 40   HHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSL----------------- 82

Query: 574  NLAQLGHPGDVGQGGLVHGGPVGGLAQPNFERE----GGSTGAGRLGTFEQQAPHLAQES 629
                              GG  GG  QP  + E    GG+  +   G  +   P L  + 
Sbjct: 83   ------------------GGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKP 124

Query: 630  AWFSGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPGE 689
                   P  G+    R    GL A  G   P   P   PGG G    GP   P      
Sbjct: 125  GDEDDAPPKMGEPAGGRYEHPGLGA-LGTQQP---PVAVPGGGG----GPAAVPEFNNYY 176

Query: 690  GH-VPALPSPGLQFGGSLGGLGQLQSPGAG-VGLPSAASERRPPPPDFATSALGGQPGFP 747
            G   PA   PG + G      G  QSPG G +   SAA+   P   D   ++  G P   
Sbjct: 177  GSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQ 236

Query: 748  FGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSL 807
                   S P +G G       GGGGGS GGGGGGGA                  GA   
Sbjct: 237  CNHYPGYSRPGAGGGGGG--GGGGGGGSGGGGGGGGA------------------GAGGA 276

Query: 808  GSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDG 867
            G+                 A++ A     A+ G               G        + G
Sbjct: 277  GA----------------GAVAAAAAAAAAAAGG--------------GGGGGYGGSSAG 306

Query: 868  AAVAGNPGSDYFPGGTAPGAPGPGGPSGTS--SSGSKASGPPNPPAQGDGTS-LSPNYTL 924
              V  +P      GG     PG GG +  S  ++GS A G      Q    S  +P    
Sbjct: 307  YGVLSSPRQQ---GGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQ 363

Query: 925  ESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGA 984
              TS +      GG                    + +YS+       P     Q  A+GA
Sbjct: 364  LLTSPSPMMRSYGGS-------------------YPEYSSPSAPPPPPSQPQSQAAAAGA 404

Query: 985  AVGG--SSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVG 1042
            A GG  ++AG   G     + A  SP+W    +      P +     G        P +G
Sbjct: 405  AAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQ---RSHPAMSPGTPG--------PTMG 453

Query: 1043 EFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPA 1102
                  +        ++     NP +  + S SP   GS    P G      G +   P 
Sbjct: 454  RSQGSPMDPMVMKRPQLYGMGSNPHSQPQQS-SPYPGGS--YGPPGPQRYPIGIQGRTPG 510

Query: 1103 LGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPPDEIHPLEILQAQIQL 1162
               G+       P  YG  G  G+      +Q + P  S    PP      + L +Q Q 
Sbjct: 511  AMAGMQYPQQQMPPQYGQQGVSGY-----CQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQ 565

Query: 1163 QRQ 1165
            + Q
Sbjct: 566  RYQ 568



 Score = 82.8 bits (203), Expect = 2e-15
 Identities = 181/796 (22%), Positives = 249/796 (31%), Gaps = 114/796 (14%)

Query: 31  NTHFKAPAFHTGGPPGPVDPAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHG 90
           N ++ + A  +GGP G   P     G     GM M            +H+    A    G
Sbjct: 173 NNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGM------------MHSASAAAAGAPG 220

Query: 91  FFGG-QQPHHGHPGS---HHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAG-GLGS 145
                Q  H G+P S   H+P    P  GG  GG   G     GG   G  GA G G G+
Sbjct: 221 SMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGA 280

Query: 146 QPPFAEGYEHMAESQGPESFGPQRPG----NLPDFHSSGASSHAVPAPCLPLDQSPNRAA 201
               A      A   G   +G    G    + P     G            L ++   +A
Sbjct: 281 VAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSA 340

Query: 202 SFHGLPSSSGSDSHSLEPRRVTNQ--GAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHY 259
           +  G    +G + H        NQ   +   +  +Y G  P  +    +P     Q    
Sbjct: 341 A-GGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPE-YSSPSAPPPPPSQPQSQ 398

Query: 260 AAGRQVPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSG 319
           AA      G    A+ M     M G     A P     QQ+  P       G    R  G
Sbjct: 399 AAAAGAAAGGQQAAAGMGLGKDM-GAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQG 457

Query: 320 ARKMPVGLEP----SVGSRHPLMQPPQQA--------PPPPQQQP------------PQQ 355
           +   P+ ++      +GS +P  QP Q +        PP PQ+ P              Q
Sbjct: 458 SPMDPMVMKRPQLYGMGS-NPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQ 516

Query: 356 PPQQQPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFEYPIHRLE 415
            PQQQ PP  G       C     +P   +   P   L      LPSQ  Q   P   + 
Sbjct: 517 YPQQQMPPQYGQQGVSGYCQQG-QQPYYSQQPQPP-HLPPQAQYLPSQSQQRYQPQQDMS 574

Query: 416 NRSMHPYSEPVFS-----------MQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFPGS 464
                  S+P  +           +Q   P   P+      D P              GS
Sbjct: 575 QEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGS 634

Query: 465 AGVDRCASWNGSMHNGA---LDNHLSP--SAYPGLPGEFTPPVPDSFPSGPPLQHPAP-D 518
                  S  G   N A      H SP  S+ PG P     P P   P G       P  
Sbjct: 635 ------TSSQGDQSNPAQSPFSPHASPHLSSIPGGPS----PSPVGSPVGSNQSRSGPIS 684

Query: 519 HQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQL 578
             S+   Q   Q    Q +        Q    ++   +   Q   +  Q   +Q   +  
Sbjct: 685 PASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMS 744

Query: 579 GHPGDVGQGGLVHGGPVGGLAQPNFEREGG--STGAGRLGTFEQQAPHLAQESAWFSGPH 636
            HP     GG +H G +    Q N     G   +  G  G + +   +    SA +SGP 
Sbjct: 745 PHP---SPGGQMHAG-ISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPG 800

Query: 637 PPPGDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPALP 696
           P  G     +M G G              P  P G+  L R P       P  G++ ++ 
Sbjct: 801 PGMGISANNQMHGQG--------------PSQPCGAVPLGRMPSAGMQNRPFPGNMSSMT 846

Query: 697 SPGLQFGGSLGGLGQLQSPGAGVGLPS-------AASERRPPPPDFATSALGGQPGFPFG 749
                   S  G+ Q   PG G  +P+       AA+       + A S  G  PG    
Sbjct: 847 P-------SSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQS 899

Query: 750 AAGRQSTPHSGPGVNS 765
                S+P+S P  NS
Sbjct: 900 GLMASSSPYSQPMNNS 915



 Score = 68.2 bits (165), Expect = 5e-11
 Identities = 125/504 (24%), Positives = 179/504 (35%), Gaps = 69/504 (13%)

Query: 703  GGSLGGLGQ----LQSPGAGVGLPSAASERRPPPPDFATSALGGQPGFP----FGAAGRQ 754
            GG+ GG  Q    ++ P  G    SAA  +  PP     S  G +   P      A GR 
Sbjct: 83   GGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRY 142

Query: 755  STPHSGP-GVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKP 813
              P  G  G   PP A       GGGGG  A P   ++  S   ++   G  +   F++ 
Sbjct: 143  EHPGLGALGTQQPPVA-----VPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQH 197

Query: 814  SSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGN 873
              + +  G   + + S A      + GAP             G     QN  +G     N
Sbjct: 198  GGQQSP-GMGMMHSASAA------AAGAP-------------GSMDPLQNSHEGYP---N 234

Query: 874  PGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGK 933
               +++PG + PGA G GG  G    GS   G       G G   +    + + +     
Sbjct: 235  SQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGG----GAGAGGAGAGAVAAAAAAAAA 290

Query: 934  PVSGGGGRGRGRRKRDSGHVS-PGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSS-- 990
               GGGG G G      G +S P          P  GGA  +S   + A+G+A GG    
Sbjct: 291  AAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLS---KAAAGSAAGGFQRF 347

Query: 991  AGETR---GAPTPHEKALTSPS---WGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEF 1044
            AG+ +   GA     + LTSPS      G        P          +S +++      
Sbjct: 348  AGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAG 407

Query: 1045 ASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAP----- 1099
                 +     +D  +  +    A   A +      SP  P   +G  +  P  P     
Sbjct: 408  GQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKR 467

Query: 1100 PPALGLGIMSNSTSTPDS---YGGG--GGPGHPGTPGLEQVRTPTSSSGAPPPDEIHPLE 1154
            P   G+G  SN  S P     Y GG  G PG    P   Q RTP + +G   P +  P +
Sbjct: 468  PQLYGMG--SNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQ 525

Query: 1155 ILQAQI----QLQRQQFSISEDQP 1174
              Q  +    Q  +Q +   + QP
Sbjct: 526  YGQQGVSGYCQQGQQPYYSQQPQP 549



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 109/462 (23%), Positives = 164/462 (35%), Gaps = 81/462 (17%)

Query: 95   QQPHHGHPGSHHPHQHHPHFGGNFGGPDPG-------ASCLHGGRLLGYGGAAGGLGSQP 147
            Q P   + GS    Q     G N     PG       AS  HG      GG +  +    
Sbjct: 1108 QPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHD 1167

Query: 148  PFAEGYEHMAESQGPE--SFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHG 205
            PF++    +++S  P+  S  P  P      +  G S   +P     +   PN+   F G
Sbjct: 1168 PFSD----VSDSSFPKRNSMTPNAP------YQQGMS---MPDVMGRMPYEPNKDP-FGG 1213

Query: 206  LPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAA---- 261
            +    GS    +   ++ N    D   YN   ++PSG          + Q P+ A+    
Sbjct: 1214 MRKVPGSSEPFMTQGQMPNSSMQDM--YN---QSPSGAMSNLGMGQRQ-QFPYGASYDRR 1267

Query: 262  ----GRQVPGGAFPGASAMPRAAGMVGLS------KMHAQ----PPQQQPQ----QQQQP 303
                G+Q PG   P +   P      GL       K H      PP ++ +      Q  
Sbjct: 1268 HEPYGQQYPGQG-PPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYS 1326

Query: 304  QQQQQQHGVFFERFSGARKMPV-GLEPSVGSRHPLMQPPQ---QAPPPPQQQPPQQPPQQ 359
             QQQ+ +  +   +SG  + P+ G  P   SR  +  P Q      PP     P Q    
Sbjct: 1327 SQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSS 1386

Query: 360  QPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFEY--PIHRLENR 417
            + P       R +     +P P Q   G P G  Q   P  P  +   +   P  R+ + 
Sbjct: 1387 EGPQQNMWAARND-----MPYPYQNRQG-PGGPTQ--APPYPGMNRTDDMMVPDQRINHE 1438

Query: 418  SMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSM 477
            S  P       +    P  + +  +Q    PP      +P +  P S       + + + 
Sbjct: 1439 SQWPSH-----VSQRQPYMSSSASMQPITRPP------QPSYQTPPSLPNHISRAPSPAS 1487

Query: 478  HNGALDNHLSPSAYPGLPG----EFTPPVPDSFPSGPPLQHP 515
               +L+N +SPS  P LP     +  P VP S  +GPP Q P
Sbjct: 1488 FQRSLENRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQPP 1529



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 206/912 (22%), Positives = 263/912 (28%), Gaps = 191/912 (20%)

Query: 335  HPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQ 394
            H L Q   Q     QQQ  QQ  QQQ   P   +   NS             G   GG  
Sbjct: 46   HALQQQLNQFQQQQQQQQQQQQQQQQQQHP---ISNNNSL------------GGAGGGAP 90

Query: 395  DGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVA 454
              GP         E P H     S             PP     ++     DAPP M   
Sbjct: 91   QPGP-------DMEQPQHGGAKDSA------AGGQADPPGPPLLSKPGDEDDAPPKMGEP 137

Query: 455  KRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPG--EFTPPVPDSFPSGPPL 512
               R++ PG                GAL     P A PG  G     P   + + S  P 
Sbjct: 138  AGGRYEHPGL---------------GALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPA 182

Query: 513  QHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQ 572
                P  ++     Q   QQ                       L        N Q     
Sbjct: 183  SG-GPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCN-HY 240

Query: 573  PNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGAGRLGTFEQQAPHLAQESA-- 630
            P  ++ G  G  G GG   GG  GG         GG  GAG  G     A   A  +A  
Sbjct: 241  PGYSRPGAGGGGGGGGGGGGGSGGGGG-------GGGAGAGGAGAGAVAAAAAAAAAAAG 293

Query: 631  -----WFSGPHPPPGDLLPRRMGGSGL---PADCGPHDPSLAPPPPPGGSGVLFRGPLQE 682
                  + G     G L   R  G G+   P   G    S A      G    F G  Q 
Sbjct: 294  GGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQH 353

Query: 683  PM-RMPGEGHVPALPSPGLQ-FGGSL-----------------------GGLGQLQSPGA 717
            P    P    +   PSP ++ +GGS                        G     Q   A
Sbjct: 354  PSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAA 413

Query: 718  GVGLPS-------------AASERRPPP---PDFATSALGGQPGFPFGAA--------GR 753
            G+GL               AA+++R  P   P      +G   G P            G 
Sbjct: 414  GMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGM 473

Query: 754  QSTPHSGPGVNSPPSAGGGG------------GSSGGGGGGGAYPPQPDFQPSQRTSASK 801
             S PHS P  +SP   G  G            G + G   G  YP Q    P Q      
Sbjct: 474  GSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQ--MPPQYGQQGV 531

Query: 802  LGALSLGS---FNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKR 858
             G    G    +++     +L  Q+    L +  Q         +      +  PP    
Sbjct: 532  SGYCQQGQQPYYSQQPQPPHLPPQA--QYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPG 589

Query: 859  K-------LSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPA 911
            K       L Q E   +    +   D  P GT          SG++SS    S P   P 
Sbjct: 590  KPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSP- 648

Query: 912  QGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGA 971
                   SP+ +    S   G P     G   G  +  SG +SP        A+      
Sbjct: 649  ------FSPHAS-PHLSSIPGGPSPSPVGSPVGSNQSRSGPISP--------ASIPGSQM 693

Query: 972  PGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSLDGG 1031
            P   PG Q  S      SS      +P P E+   + +         G Q        G 
Sbjct: 694  PPQPPGSQSES------SSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQT------GP 741

Query: 1032 AKSDSSSPN------VGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLP 1085
            + S   SP       +  F     S +Y  +     S   PQ     SR P  +G P   
Sbjct: 742  SMSPHPSPGGQMHAGISSFQQSNSSGTYGPQ----MSQYGPQG--NYSRPPAYSGVPSAS 795

Query: 1086 PRGVGAGE----------HGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQV 1135
              G G G            GP  P  A+ LG M ++      + G      P +PG+ Q 
Sbjct: 796  YSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQ 855

Query: 1136 RTPTSSSGAPPP 1147
              P    G P P
Sbjct: 856  GGP--GMGPPMP 865



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 178/865 (20%), Positives = 269/865 (31%), Gaps = 202/865 (23%)

Query: 94   GQQPHHGHPGSHHPHQHHPHFGGNFGGPDP-----GASCLHGGRLLG-----------YG 137
            G  PH        P Q  P+ GG++G P P     G      G + G           YG
Sbjct: 474  GSNPHS------QPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYG 527

Query: 138  --GAAG----------GLGSQPPFAEGYEHMAESQGPESFGPQRPGNLPDFHSSGASSHA 185
              G +G              QPP          SQ  + + PQ+     D    G  + +
Sbjct: 528  QQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQ-----DMSQEGYGTRS 582

Query: 186  VP--APCLPLDQSPNRAASFH--GLPSSSGSDSHSLEPRRVTNQGAVD-SLEYNYPGEAP 240
             P  AP  P  +  N         LP  SGS          T   AV  S   +  G+  
Sbjct: 583  QPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQS 642

Query: 241  SGHFDMFSPSDSEGQLPHYAAGRQVPGGAFPGASAMPRAAGMVGLSKMHAQP--PQQQPQ 298
            +     FSP  S    PH ++   +PGG  P     P     VG ++  + P  P   P 
Sbjct: 643  NPAQSPFSPHAS----PHLSS---IPGGPSPSPVGSP-----VGSNQSRSGPISPASIPG 690

Query: 299  QQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQ 358
             Q  PQ    Q        S +   P   +  +      M   Q+ P   Q  P Q  P 
Sbjct: 691  SQMPPQPPGSQ--------SESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPS 742

Query: 359  QQPPPPP------GLLVRQNSCPPALPRPQQGE-------------AGTPSGGLQDGGPM 399
              P P P      G+   Q S       PQ  +             +G PS      GP 
Sbjct: 743  MSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPG 802

Query: 400  L------------PSQHAQF----EYPIHRLENR-------SMHPYSEPVFSMQHP---P 433
            +            PSQ          P   ++NR       SM P S  +     P   P
Sbjct: 803  MGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGP 862

Query: 434  PQQAPNQRLQHFDAPPYM---NVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSA 490
            P    N++ Q   A       N A+  +  FPG       AS   S ++  ++N  S   
Sbjct: 863  PMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMAS--SSPYSQPMNNSSSLMN 920

Query: 491  YPGLPGEFTPPVPDSFPSGPPLQHP-APDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQ 549
                P    P + +S  +   L    +P    L    +   +++   Q + + ++     
Sbjct: 921  TQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKKSSSST 980

Query: 550  QRQNAALMIKQMASRNQQQRLRQPNLAQLGHPGD-------VGQGGL------VHGGPVG 596
                    + ++ +  +++      L  +   G        VG+  L      V    +G
Sbjct: 981  TTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIG 1040

Query: 597  GLAQPNFEREGGSTGAG-RLGTFEQQAPHLAQESAWF---------SGPHPPP------- 639
            GLAQ N  ++         +GT    A  L ++   +          G  PPP       
Sbjct: 1041 GLAQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGD 1100

Query: 640  -------------------GDLLPRRMGGSGL---PADCGPHDPSLAP----PPPPGG-- 671
                               G   P+  G + +   P D  P  P+  P     P  GG  
Sbjct: 1101 TKKQPKLQPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRS 1160

Query: 672  --------------------SGVLFRGPLQEPMRMPGE-GHVPALPSPGLQFGGSLGGLG 710
                                + +    P Q+ M MP   G +P  P+    FGG     G
Sbjct: 1161 STISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKD-PFGGMRKVPG 1219

Query: 711  QLQSPGAGVGLPSAASE---RRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPP 767
              +       +P+++ +    + P    +   +G +  FP+GA+      H   G   P 
Sbjct: 1220 SSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGAS--YDRRHEPYGQQYPG 1277

Query: 768  SAGGGGGSSGGGGGGGAYPPQPDFQ 792
                 G    GG   G YP QP+++
Sbjct: 1278 QGPPSGQPPYGGHQPGLYPQQPNYK 1302



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 33/102 (32%), Positives = 40/102 (39%), Gaps = 14/102 (13%)

Query: 294 QQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQPP 353
           QQQ QQQQQ QQQQQQH +      G            G   P   P  + P     +  
Sbjct: 58  QQQQQQQQQQQQQQQQHPISNNNSLG----------GAGGGAPQPGPDMEQPQHGGAKDS 107

Query: 354 QQPPQQQPPPPPGLLVR---QNSCPPALPRPQQGEAGTPSGG 392
               Q  PP PP LL +   ++  PP +  P  G    P  G
Sbjct: 108 AAGGQADPPGPP-LLSKPGDEDDAPPKMGEPAGGRYEHPGLG 148



 Score = 33.1 bits (74), Expect = 1.8
 Identities = 81/347 (23%), Positives = 117/347 (33%), Gaps = 83/347 (23%)

Query: 51   AMSALGEPPILGMNME-PYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHGHPGSHHPHQ 109
            AMS LG    +G   + PYG     +   H    Q  P  G   GQ P+ GH    +P Q
Sbjct: 1246 AMSNLG----MGQRQQFPYG---ASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQ 1298

Query: 110  --HHPHFGGNFGGPDPGASCLHGGRLLG-------------YGGAAGGLGSQPPFAEGYE 154
              +  H  G +G P    +  H G +               YGG+  G   +P       
Sbjct: 1299 PNYKRHMDGMYGPP----AKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRP------- 1347

Query: 155  HMAESQGPESFGPQR---PGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSG 211
               + Q P  +  +R   PG +         +H +P   +     P +++S  G   +  
Sbjct: 1348 --IQGQYPYPYSRERMQGPGQI--------QTHGIPPQMM---GGPLQSSSSEGPQQNMW 1394

Query: 212  SDSHSLEPRRVTNQGAVDSLEY-NYPGEAPSGHFDMFSPS---DSEGQLPHYAAGRQVPG 267
            +  + +       QG     +   YPG   +   DM  P    + E Q P + + RQ   
Sbjct: 1395 AARNDMPYPYQNRQGPGGPTQAPPYPGMNRTD--DMMVPDQRINHESQWPSHVSQRQ--- 1449

Query: 268  GAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQH-GVFFERFSGARKMPVG 326
                    M  +A M        QP  + PQ   Q       H        S  R +   
Sbjct: 1450 ------PYMSSSASM--------QPITRPPQPSYQTPPSLPNHISRAPSPASFQRSLENR 1495

Query: 327  LEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPP-------PPG 366
            + PS     P M+  +  P  P  Q    PP  QPPP       PPG
Sbjct: 1496 MSPSKSPFLPSMKMQKVMPTVPTSQVTGPPP--QPPPIRREITFPPG 1540


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score = 94.4 bits (233), Expect = 7e-19
 Identities = 255/1021 (24%), Positives = 320/1021 (31%), Gaps = 209/1021 (20%)

Query: 43   GPPGPVDPAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHGHP 102
            GPPGP  P       P + GM+ +P     +G+      G Q +P      G     G+P
Sbjct: 688  GPPGPPGP-------PGVTGMDGQP---GPKGNV-----GPQGEP------GPPGQQGNP 726

Query: 103  GSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHMAESQGP 162
            G+    Q  P   G  G P         G L G  GA G  G   P  EG       QGP
Sbjct: 727  GA----QGLPGPQGAIGPPGEKGPLGKPG-LPGMPGADGPPGH--PGKEGPPGEKGGQGP 779

Query: 163  ESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDSHSLEPRRV 222
               GPQ P   P                    +    A    GL  + G       P   
Sbjct: 780  P--GPQGPIGYPG------------------PRGVKGADGIRGLKGTKGEKGEDGFPGFK 819

Query: 223  TNQGAV-DSLEYNYPGE-------------APSGHFDMFSPSDSEGQL-----PHYAAGR 263
             + G   D  E   PG               P+G      P   +G+L     P Y  GR
Sbjct: 820  GDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYP-GR 878

Query: 264  QVPGGA-----FPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFS 318
            Q P G+     FPGA+      G  G      Q     P+ ++ P+    + G       
Sbjct: 879  QGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGG 938

Query: 319  GARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQP--PQQPPQQQ---------PPPPPGL 367
                 P G     G + P   P  + PP P  +   P  P Q+          PP PPG+
Sbjct: 939  DGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGV 998

Query: 368  LVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVF 427
            +  Q       P  ++G  G P    + G P L  +                        
Sbjct: 999  VGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEG---------------------- 1036

Query: 428  SMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLS 487
            +   P P   P +     D PP +         FPG  G+       G   N        
Sbjct: 1037 TKGDPGPAGLPGK-----DGPPGLR-------GFPGDRGLPGPVGALGLKGNEGPPGPPG 1084

Query: 488  PSAYPGLPGEFTPPVPDSFPSGP-PLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQ 546
            P+  PG  G      P   P  P P   P P         ++    ++  Q    +   Q
Sbjct: 1085 PAGSPGERGPAGAAGPIGIPGRPGPQGPPGP-------AGEKGAPGEKGPQGPAGRDGLQ 1137

Query: 547  QQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVG-QGGLVHGGPVGGLAQPNFER 605
                    A  +        +  + +P   Q G  GD G QG     GP G + QP    
Sbjct: 1138 GPVGLPGPAGPVGPPGEDGDKGEIGEP--GQKGSKGDKGEQGPPGPTGPQGPIGQPGPSG 1195

Query: 606  EGGSTG-AGRLGTFEQQAPHLAQESAWFSGPHPPPG-DLLP---------RRMGGSGLPA 654
              G  G  G+ G F Q+     +    F GP  P G   LP           +G  G P 
Sbjct: 1196 ADGEPGPRGQQGLFGQKGD---EGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPG 1252

Query: 655  DCGPHDPSLA-----PPPPPGGSGVLFRGPLQEPMRMPGEGHVPALPSPGLQFG--GSLG 707
              GP  PS A     P  PPGG G    G + E    PGE   P LP  G   G  G  G
Sbjct: 1253 PPGPRGPSGAPGADGPQGPPGGIG--NPGAVGEKGE-PGEAGEPGLPGEGGPPGPKGERG 1309

Query: 708  GLGQLQSPGAGVGLPSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGP-GVNSP 766
              G+   P    G P      + PP D       G  GFP G  G    P  GP G + P
Sbjct: 1310 EKGE-SGPSGAAGPPGP----KGPPGDDGPKGSPGPVGFP-GDPGPPGEP--GPAGQDGP 1361

Query: 767  PSAGGGGGSSG-GGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCL 825
            P   G  G  G  G  G    P P   P +R      G         P  +    G    
Sbjct: 1362 PGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAG---------PEGRQGEKGAKGE 1412

Query: 826  AALS--TACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGT 883
            A L         I   GAP        K  P+G R           + G  G    PG  
Sbjct: 1413 AGLEGPPGKTGPIGPQGAPG-------KPGPDGLR----------GIPGPVGEQGLPGSP 1455

Query: 884  AP-GAPGPGGPSGTSSSGSKA-SGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGG--G 939
             P G PGP GP G    G K  SGP           L      +   G+ G P   G  G
Sbjct: 1456 GPDGPPGPMGPPGL--PGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSG 1513

Query: 940  GRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPT 999
             +G       SG + P          P   G PG  PG + A G++      GE  G P 
Sbjct: 1514 PKGEQGITGPSGPIGP----------PGPPGLPG-PPGPKGAKGSSGPTGPKGEA-GHPG 1561

Query: 1000 P 1000
            P
Sbjct: 1562 P 1562



 Score = 82.8 bits (203), Expect = 2e-15
 Identities = 168/624 (26%), Positives = 214/624 (34%), Gaps = 84/624 (13%)

Query: 579  GHPGDVGQGGLVHG-GPVGGLAQPNFEREGGSTGA-GRLGTFEQQAPHLAQESAWFSG-P 635
            G PG+ G  GL+   GP G    P      G  G  G +G   +  P   Q +    G P
Sbjct: 673  GLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLP 732

Query: 636  HP-----PPGDLLPR-RMGGSGLPADCGP--HDPSLAPPPPPGGSGVLFRGPLQEPMRMP 687
             P     PPG+  P  + G  G+P   GP  H     PP   GG G    GP Q P+  P
Sbjct: 733  GPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGP--PGP-QGPIGYP 789

Query: 688  GEGHVPALPS-PGLQFGGSLGGLGQLQSPG--AGVGLPSAASERRPPPPDFATSALG--- 741
            G   V       GL+  G+ G  G+   PG    +G+     E  PP P       G   
Sbjct: 790  GPRGVKGADGIRGLK--GTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKG 847

Query: 742  -----GQPG--FPFGAAGRQSTPH--SGPGVNSPPSAGGGGGSSGGGG--GGGAYPPQPD 790
                 G PG   P G  G+   P     PG   P  + G  G  G  G  GG   P +P 
Sbjct: 848  RGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPG 907

Query: 791  FQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTF-N 849
             +  +  +  +      G   KP  K N  G            N       P     F  
Sbjct: 908  PRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPN------GPQGPTGFPG 961

Query: 850  KKNPPEGKRKLSQNETDGA-AVAGNPGSDYFPGGTAPGAP----GPGGPSG-TSSSGSKA 903
             K PP    K      DG     G  G   F G T P  P    GP GP+G T   G + 
Sbjct: 962  PKGPPGPPGK------DGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERG 1015

Query: 904  S-GPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSP-GTFFDK 961
              GPP PP +     L+     +   G  G P   G    RG    D G   P G    K
Sbjct: 1016 HPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGF-PGDRGLPGPVGALGLK 1074

Query: 962  YSAAPDSGGAPGVSPGQQQASGAA--VGGSSAGETRGAP-------TPHEKALTSPSWGK 1012
             +  P     P  SPG++  +GAA  +G       +G P        P EK    P+   
Sbjct: 1075 GNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRD 1134

Query: 1013 GAELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKA 1072
            G +  +G  P   G + G    D     +GE    +  +     ++       PQ  +  
Sbjct: 1135 GLQGPVG-LPGPAGPV-GPPGEDGDKGEIGE--PGQKGSKGDKGEQGPPGPTGPQGPIGQ 1190

Query: 1073 SRSPLVTGSPKLPPRGVGA-----GEHGPK---APPPALGLGIMSNSTSTPDSYGGGGGP 1124
                   G P   PRG        G+ GP+    PP  +GL  +          G  G  
Sbjct: 1191 PGPSGADGEPG--PRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQM 1248

Query: 1125 GHPGTPGLEQVRTPTSSSGAPPPD 1148
            G PG PG      P   SGAP  D
Sbjct: 1249 GPPGPPG------PRGPSGAPGAD 1266



 Score = 82.8 bits (203), Expect = 2e-15
 Identities = 177/631 (28%), Positives = 206/631 (32%), Gaps = 132/631 (20%)

Query: 579  GHPGDVG-QGGLVHGGPVGGLAQPNFEREGGSTG----AGRLGTFEQQAPHLAQESAWFS 633
            G PG VG QG     GP+G    P      G  G    AG+ GT     P          
Sbjct: 994  GPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPP 1053

Query: 634  GPHPPPGDL-LPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQE--PMRMPGEG 690
            G    PGD  LP  +G  GL  + GP      PP P G  G   RGP     P+ +PG  
Sbjct: 1054 GLRGFPGDRGLPGPVGALGLKGNEGPP----GPPGPAGSPGE--RGPAGAAGPIGIPGRP 1107

Query: 691  HVPALPSPGLQFG-----GSLGGLGQ--LQSPGAGVGLPSAASERRPPPPDFATSALG-- 741
                 P P  + G     G  G  G+  LQ P   VGLP  A    PP  D     +G  
Sbjct: 1108 GPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGP---VGLPGPAGPVGPPGEDGDKGEIGEP 1164

Query: 742  GQPGFPFGAAGRQSTPH-SGP-GVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSA 799
            GQ G   G  G Q  P  +GP G    P   G  G  G  G  G +  + D  P  R   
Sbjct: 1165 GQKGSK-GDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGP--RGFP 1221

Query: 800  SKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRK 859
               G + L     P  +    G              +  +G P          PP  +  
Sbjct: 1222 GPPGPVGLQGLPGPPGEKGETGD-------------VGQMGPPG---------PPGPRGP 1259

Query: 860  LSQNETDGAAVAGNPGSDYFPGGTA----------PGAPGPGGPSGTS--------SSGS 901
                  DG    G PG    PG             PG PG GGP G          S  S
Sbjct: 1260 SGAPGADGPQ--GPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPS 1317

Query: 902  KASGPPNP--PAQGDGTSLSPNYTLESTSGNDGKPVSGG--GGRGRGRRKRDSGHV---- 953
             A+GPP P  P   DG   SP        G+ G P   G  G  G    K D G      
Sbjct: 1318 GAAGPPGPKGPPGDDGPKGSPGPV--GFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTG 1375

Query: 954  SPG-TFFDKYSAAPDSGGAPGVS-----PGQQQASGAAVGGSSAGET------------- 994
            SPG T     S  P   G PG +      G++ A G A      G+T             
Sbjct: 1376 SPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPG 1435

Query: 995  ----RGAPTP-HEKALTSPSWGKGAELLLGDQ--PDLIGSLDGGAKSDSSSPNV------ 1041
                RG P P  E+ L       G    +G    P L G  D G K +   P +      
Sbjct: 1436 PDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKG--DSGPKGEKGHPGLIGLIGP 1493

Query: 1042 -GEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPP 1100
             GE    E         + SS     Q +   S      G P LP         GP  P 
Sbjct: 1494 PGE--QGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLP---------GPPGPK 1542

Query: 1101 PALGLGIMSNSTSTPDSYGGGGGPGHPGTPG 1131
             A G    S  T      G  G PG PG PG
Sbjct: 1543 GAKG---SSGPTGPKGEAGHPGPPGPPGPPG 1570



 Score = 82.4 bits (202), Expect = 3e-15
 Identities = 163/607 (26%), Positives = 200/607 (32%), Gaps = 98/607 (16%)

Query: 579  GHPGDVGQGGLV----HGGPVGGLAQPNFEREGGSTGAGRLGTFEQQAPHLAQESAWFSG 634
            G PG  GQ G        GP G   +P    +G S G G  G   ++ P+  Q    F G
Sbjct: 904  GKPGPRGQRGPTGPRGERGPRGITGKPG--PKGNSGGDGPAGPPGERGPNGPQGPTGFPG 961

Query: 635  PHPPPGDLLPRRMGGSGLPADCGP--HDPSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHV 692
            P  PPG   P + G  G P   G         PP PPG  G   +GP  E   M   GH 
Sbjct: 962  PKGPPGP--PGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGP--QGPTGETGPMGERGH- 1016

Query: 693  PALPSPGLQFG--GSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALGGQPGFPFGA 750
            P  P P  + G  G  G  G    PG   GLP     +  PP         G PG P GA
Sbjct: 1017 PGPPGPPGEQGLPGLAGKEGTKGDPGPA-GLPG----KDGPPGLRGFPGDRGLPG-PVGA 1070

Query: 751  AGRQST--PHSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLG 808
             G +    P   PG    P   G  G++G  G  G   PQ    P     A + GA    
Sbjct: 1071 LGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGP-----AGEKGAPGEK 1125

Query: 809  SFNKPSSKDNLFGQSCLAALSTAC--------QNMIASLGAPNLNVTFNKKNPPEG---K 857
                P+ +D L G   L   +           +  I   G         ++ PP     +
Sbjct: 1126 GPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQ 1185

Query: 858  RKLSQNETDGA-------------AVAGNPGSDYFPGGTAP----GAPGPGGPSGTSSSG 900
              + Q    GA                G+ G   FPG   P    G PGP G  G +   
Sbjct: 1186 GPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDV 1245

Query: 901  SKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVS-PGTFF 959
             +  GPP PP    G S +P        G  G P  G G  G    K + G    PG   
Sbjct: 1246 GQM-GPPGPPGPR-GPSGAPG-----ADGPQGPP-GGIGNPGAVGEKGEPGEAGEPGL-- 1295

Query: 960  DKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLG 1019
                  P  GG PG   G++   G +    +AG       P +     P    G     G
Sbjct: 1296 ------PGEGGPPGPK-GERGEKGESGPSGAAGPPGPKGPPGDDG---PKGSPGPVGFPG 1345

Query: 1020 DQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVT 1079
            D P   G   G A  D    + G+      + S     E   S           R P   
Sbjct: 1346 D-PGPPGE-PGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGP------PGKRGPPGP 1397

Query: 1080 GSPKLPPRGVGA-GEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTP 1138
              P+      GA GE G + PP   G              G  G PG PG  GL  +  P
Sbjct: 1398 AGPEGRQGEKGAKGEAGLEGPPGKTG------------PIGPQGAPGKPGPDGLRGIPGP 1445

Query: 1139 TSSSGAP 1145
                G P
Sbjct: 1446 VGEQGLP 1452



 Score = 82.0 bits (201), Expect = 3e-15
 Identities = 179/705 (25%), Positives = 230/705 (32%), Gaps = 113/705 (16%)

Query: 486  LSPSAYPGLPGEFTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQ 545
            + P+   G PGE  PP     P    L  P P    +   +         +      Q+ 
Sbjct: 486  MGPTGQVGDPGERGPPGRPGLPGADGLPGP-PGTMLMLPFRFGGGGDAGSKGPMVSAQES 544

Query: 546  QQQQQRQNAALMIK----QMASRNQQQRLRQPNLAQL-GHPGDVG-QGGLVHGGPVGGLA 599
            Q Q   Q A L ++     M    +   +  P    L G PGDVG QG     GP G   
Sbjct: 545  QAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAG 604

Query: 600  QPNFEREGGSTGA----GRLGT-----FEQQAPHLAQE----SAWFSGPHPPPGDLLPR- 645
            +P      GS GA    G+ G      F+  A    ++        SGP  PPGD   R 
Sbjct: 605  KPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERG 664

Query: 646  ---RMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPALPSPGLQF 702
                +G  GLP + GP    L P  PPG            P   PG   +   P P    
Sbjct: 665  DDGEVGPRGLPGEPGPRG-LLGPKGPPG------------PPGPPGVTGMDGQPGPKGNV 711

Query: 703  G--GSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSG 760
            G  G  G  GQ  +PGA  GLP       PP          G+PG P             
Sbjct: 712  GPQGEPGPPGQQGNPGA-QGLPGPQGAIGPP----GEKGPLGKPGLP-----------GM 755

Query: 761  PGVNSPPSAGGGGGSSGGGGGGGAYPPQ-PDFQPSQRTSASKLGALSLGSFNKPSSKDNL 819
            PG + PP   G  G  G  GG G   PQ P   P  R      G   L        +D  
Sbjct: 756  PGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGF 815

Query: 820  FGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVA--GNPGSD 877
             G           +     +G P        ++ PEG +       D   +   G  G  
Sbjct: 816  PGFKG----DMGIKGDRGEIGPPGP----RGEDGPEGPKGRGGPNGDPGPLGPPGEKGKL 867

Query: 878  YFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSG 937
              PG   PG PG  GP G+         P  P A G+          +   G  GKP   
Sbjct: 868  GVPG--LPGYPGRQGPKGS------IGFPGFPGANGE----------KGGRGTPGKP--- 906

Query: 938  GGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGG-APGVSPGQQQASGAAVGGSSAGETRG 996
             G RG+       G   P     K     +SGG  P   PG++  +G   G +     +G
Sbjct: 907  -GPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQ-GPTGFPGPKG 964

Query: 997  APTPHEK-ALTSPSWGKGAELLLG-----DQPDLIG----SLDGGAKSDSSSPNVGEFAS 1046
             P P  K  L      +G     G       P ++G    + + G   +   P       
Sbjct: 965  PPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPG 1024

Query: 1047 DEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSP--KLPPRGVGA----GEHGPKAPP 1100
            ++     A + E +     P  L      P + G P  +  P  VGA    G  GP  PP
Sbjct: 1025 EQGLPGLAGK-EGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPP 1083

Query: 1101 PALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAP 1145
               G      S       G  G  G PG PG +    P    GAP
Sbjct: 1084 GPAG------SPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAP 1122



 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 161/610 (26%), Positives = 194/610 (31%), Gaps = 130/610 (21%)

Query: 579  GHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGAGRLGTF----EQQAPHLAQESAW-FS 633
            G PG  G  GL   GP G +    F R GG   AG  G      E QA  + Q++     
Sbjct: 502  GRPGLPGADGLP--GPPGTMLMLPF-RFGGGGDAGSKGPMVSAQESQAQAILQQARLALR 558

Query: 634  GPHPP------PGDLLPRRMGG-SGLPADCGPHDPS--LAPPPPPGGSGVLFRGPLQEPM 684
            GP  P      PG + P   GG  G P D GP  P     PP P G  G   R       
Sbjct: 559  GPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGAR 618

Query: 685  RMPGEGHVPALPSPGLQFGGSLGGL----GQLQSPG-AGVGLPSAASERRPPPPDFATSA 739
             MPG+      P     F G L GL    G    PG +G   P      R    +     
Sbjct: 619  GMPGQTG----PKGDRGFDG-LAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRG 673

Query: 740  LGGQPGFPFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGGGGAY----PPQPDFQPSQ 795
            L G+PG P G  G    P   PG   PP   G  G  G  G  G      PP     P  
Sbjct: 674  LPGEPG-PRGLLG----PKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGA 728

Query: 796  RTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPE 855
            +      GA+       P  K  L G             M  + G P       K+ PP 
Sbjct: 729  QGLPGPQGAIGPPGEKGPLGKPGLPG-------------MPGADGPPGHP---GKEGPP- 771

Query: 856  GKRKLSQNETDGAAVAGNPGSDYFPGGTA-PGAPGPGGPSGTSSSGSKASGPP---NPPA 911
                    E  G    G  G   +PG     GA G  G  GT     +   P    +   
Sbjct: 772  -------GEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGI 824

Query: 912  QGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGA 971
            +GD   + P        G DG      G +GRG    D G + P     K        G 
Sbjct: 825  KGDRGEIGP----PGPRGEDGPE----GPKGRGGPNGDPGPLGPPGEKGKLGVP----GL 872

Query: 972  PGVSPGQQQASGA--------AVGGSSAGETRGAPTPH-EKALTSPSWGKGAELLLGDQP 1022
            PG  PG+Q   G+        A G      T G P P  ++  T P   +G   + G   
Sbjct: 873  PGY-PGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKP- 930

Query: 1023 DLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSP 1082
                    G K +S                           D P A     R P     P
Sbjct: 931  --------GPKGNSGG-------------------------DGP-AGPPGERGP---NGP 953

Query: 1083 KLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSS 1142
            + P      G  GPK PP   G   +          G  G  G PG PG+   + PT  +
Sbjct: 954  QGP-----TGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGET 1008

Query: 1143 GAPPPDEIHP 1152
            G P  +  HP
Sbjct: 1009 G-PMGERGHP 1017



 Score = 68.2 bits (165), Expect = 5e-11
 Identities = 148/598 (24%), Positives = 189/598 (31%), Gaps = 113/598 (18%)

Query: 564  RNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGA-GRLGTFEQQA 622
            RN  +    P       P ++G G   +   +       +E  GG  G  G+ G      
Sbjct: 410  RNLDENYYDPYYDPTSSPSEIGPGMPANQDTI-------YEGIGGPRGEKGQKGE----- 457

Query: 623  PHLAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQE 682
            P + +      GP  P G         +GLP   G    ++ P    G  G   RGP   
Sbjct: 458  PAIIEPGMLIEGPPGPEGP--------AGLPGPPG----TMGPTGQVGDPGE--RGPPGR 503

Query: 683  PMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALGG 742
            P  +PG   +P  P   L      GG G   S G  V   SA   +       A  AL G
Sbjct: 504  P-GLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMV---SAQESQAQAILQQARLALRG 559

Query: 743  QPGFPFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGGGGAY----PPQPDFQPSQRTS 798
              G P G  GR       PG   PP +GG  G  G  G  G      PP P  +P +R  
Sbjct: 560  PAG-PMGLTGR-------PGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGR 611

Query: 799  ASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPP--EG 856
            A   GA  +     P       G + L              G P  +       PP  +G
Sbjct: 612  AGSDGARGMPGQTGPKGDRGFDGLAGLPGEK-------GHRGDPGPS---GPPGPPGDDG 661

Query: 857  KRKLSQNETDGAAVAGNPGSDYFPGGTA-PGAPGPGGPSGTSSS-GSKAS----GPPNPP 910
            +R     E     + G PG     G    PG PGP G +G     G K +    G P PP
Sbjct: 662  ERG-DDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPP 720

Query: 911  AQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGG 970
             Q            +   G  G P    G  G    K   G   PG         P + G
Sbjct: 721  GQ------------QGNPGAQGLP-GPQGAIGPPGEKGPLG--KPG-----LPGMPGADG 760

Query: 971  APGVSPGQQQASGAAVGGSSAGETRGAPTPHEK-ALTSPSWGKGAELLLGDQPDLIGSLD 1029
             PG  PG++   G   G       +G P P        P   KGA+ + G +        
Sbjct: 761  PPG-HPGKEGPPGEKGG-------QGPPGPQGPIGYPGPRGVKGADGIRGLK-------- 804

Query: 1030 GGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGV 1089
             G K +        F  D           +    D  +      R       PK   RG 
Sbjct: 805  -GTKGEKGEDGFPGFKGD-----------MGIKGDRGEIGPPGPRGEDGPEGPK--GRGG 850

Query: 1090 GAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPP 1147
              G+ GP  PP   G   +      P   G  G  G PG PG    +    + G P P
Sbjct: 851  PNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGP 908



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 74/243 (30%), Positives = 89/243 (36%), Gaps = 37/243 (15%)

Query: 578  LGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTG-AGRLGTFEQQAPHLAQESAWFSGPH 636
            +G PGD G  G    GP G    P  + + G  G  G  G   +  P          GP 
Sbjct: 1341 VGFPGDPGPPG--EPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPA 1398

Query: 637  PPPGDLLPRRMGGS----GLPADCGPHDPSLAP--PPPPGGSGVLFRGPLQE-------- 682
             P G    +   G     G P   GP  P  AP  P P G  G+   GP+ E        
Sbjct: 1399 GPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGI--PGPVGEQGLPGSPG 1456

Query: 683  PMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPG--AGVGLPSAASER--RPPPPDFATS 738
            P   PG    P LP  GL+  G  G  G+   PG    +G P    E+  R  P    +S
Sbjct: 1457 PDGPPGPMGPPGLP--GLK--GDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSS 1512

Query: 739  ALGGQPGF--PFGAAGRQSTPHSGPGVNSPPSAGGGGGSSG----GGGGGGAYPPQPDFQ 792
               G+ G   P G  G    P   PG+  PP   G  GSSG     G  G   PP P   
Sbjct: 1513 GPKGEQGITGPSGPIG----PPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGP 1568

Query: 793  PSQ 795
            P +
Sbjct: 1569 PGE 1571



 Score = 50.8 bits (120), Expect = 8e-06
 Identities = 178/722 (24%), Positives = 226/722 (31%), Gaps = 120/722 (16%)

Query: 9    PQVNSRNAGQ----GERNFNETGLSMNTHFKAPAFHTGGPPGPVDPAMSALGEPPILGMN 64
            P+ NS   G     GER  N  G    T F  P     GPPGP  P    L   P  G  
Sbjct: 932  PKGNSGGDGPAGPPGERGPN--GPQGPTGFPGPK----GPPGP--PGKDGLPGHP--GQR 981

Query: 65   MEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHGHPGSHHP--HQHHPHFGGNFGGP- 121
             E  GF  +       G +  Q   G  G      GHPG   P   Q  P   G  G   
Sbjct: 982  GET-GFQGKTGPPGPPGVVGPQGPTGETG-PMGERGHPGPPGPPGEQGLPGLAGKEGTKG 1039

Query: 122  DPGASCLHGGRLLGYGGAAGGLGSQP-PFAEGYEHMAESQGPESFGPQRPGNLPDFHSSG 180
            DPG + L G    G  G  G  G +  P   G   +  ++GP   GP  P   P      
Sbjct: 1040 DPGPAGLPGKD--GPPGLRGFPGDRGLPGPVGALGLKGNEGPP--GPPGPAGSPGERGPA 1095

Query: 181  ASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEA- 239
             ++  +  P  P  Q P   A   G P   G    +    R   QG V       PG A 
Sbjct: 1096 GAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPA---GRDGLQGPV-----GLPGPAG 1147

Query: 240  PSGHFDMFSPSDSEGQLPHYAAGRQVPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQ 299
            P G      P   +G         Q       G    P   G  G      QP       
Sbjct: 1148 PVG------PPGEDGDKGEIGEPGQKGSKGDKGEQGPP---GPTGPQGPIGQPGPSGADG 1198

Query: 300  QQQPQQQQQQHGVFFER-FSGARKMP--------VGLEPSVGSRHPLMQPPQQAP--PPP 348
            +  P+ QQ   G+F ++   G R  P         GL    G +       Q  P  PP 
Sbjct: 1199 EPGPRGQQ---GLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPG 1255

Query: 349  QQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFE 408
             + P   P    P  PPG +    +      + + GEAG P G   +GGP  P       
Sbjct: 1256 PRGPSGAPGADGPQGPPGGIGNPGAVG---EKGEPGEAGEP-GLPGEGGPPGPK------ 1305

Query: 409  YPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFPGSAGVD 468
                    R     S P  +   P P+  P       D P            FPG  G  
Sbjct: 1306 ------GERGEKGESGPSGAAGPPGPKGPPGD-----DGPK----GSPGPVGFPGDPGPP 1350

Query: 469  RCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVP--DSFPSGPPLQHPAPDHQSLQQQQ 526
                  G       D         G PG+   P P  +  PSGPP +   P         
Sbjct: 1351 ------GEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAG----- 1399

Query: 527  QQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQ 586
                 + +Q ++  + +   +    +   +  +    +     LR       G PG VG+
Sbjct: 1400 ----PEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLR-------GIPGPVGE 1448

Query: 587  GGLVHG-------GPVGGLAQPNFEREGGSTG-AGRLGTFEQQAPHLAQESAWFSGPHPP 638
             GL          GP+G    P  + + G  G  G  G      P   Q      G   P
Sbjct: 1449 QGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGP 1508

Query: 639  PGDLLPRRMGGSGLPADCGPHDPSLAP--PPPPGGSGVLFRGPLQEPMRMPGEGHVPALP 696
             G   P+  G  G+    GP  P   P  P PPG  G   +G    P    GE   P  P
Sbjct: 1509 QGSSGPK--GEQGITGPSGPIGPPGPPGLPGPPGPKGA--KGS-SGPTGPKGEAGHPGPP 1563

Query: 697  SP 698
             P
Sbjct: 1564 GP 1565



 Score = 41.2 bits (95), Expect = 0.007
 Identities = 96/399 (24%), Positives = 121/399 (30%), Gaps = 82/399 (20%)

Query: 37  PAFHTGGPPGPVDPAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQ 96
           P     GPPGP  PA   L  PP     M P G       ++   G +  P      G  
Sbjct: 463 PGMLIEGPPGPEGPA--GLPGPP---GTMGPTG-------QVGDPGERGPPGRPGLPGAD 510

Query: 97  PHHGHPGSHHPHQHHPHFGGNFGGPDPGASC--------LHGGRL--------LGYGGAA 140
              G PG+          GG+ G   P  S         L   RL        +G  G  
Sbjct: 511 GLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRP 570

Query: 141 GGLGSQPPFAEGYEHMAESQGPES----FGPQRPGNLPDFHSSGASSHAVPAPCLPLDQS 196
           G +G  PP + G +      GP+      GP  P   P       S     A  +P    
Sbjct: 571 GPVG--PPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSD---GARGMPGQTG 625

Query: 197 PNRAASFHGLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQL 256
           P     F GL    G   H  +P                P   P    D     D     
Sbjct: 626 PKGDRGFDGLAGLPGEKGHRGDPG---------------PSGPPGPPGDDGERGDDGEVG 670

Query: 257 PHYAAGRQVPGGAFPGASAMPRAAGMVGLSKMHAQP-PQQQPQQQQQPQQQQQQHGVFFE 315
           P    G   P G   G    P   G  G++ M  QP P+     Q +P    QQ     +
Sbjct: 671 PRGLPGEPGPRGLL-GPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQ 729

Query: 316 RFSGARKMPVGLEPSVGSRHPLMQPPQQAPP--------PPQQQPPQQPPQQQPPPPPGL 367
              G    P G     G + PL +P     P        P ++ PP +   Q PP P G 
Sbjct: 730 GLPG----PQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQG- 784

Query: 368 LVRQNSCPPALPRPQ--------QGEAGTPSGGLQDGGP 398
                  P   P P+        +G  GT     +DG P
Sbjct: 785 -------PIGYPGPRGVKGADGIRGLKGTKGEKGEDGFP 816



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 64/273 (23%), Positives = 84/273 (30%), Gaps = 58/273 (21%)

Query: 885  PGAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGND------------- 931
            P  PG G    TS++ +  S  P PP       L   +T E+    D             
Sbjct: 367  PTDPGAGAEIPTSTADTSNSSNPAPPPGEGADDLEGEFTEETIRNLDENYYDPYYDPTSS 426

Query: 932  ------GKPVSG-------GGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQ 978
                  G P +        GG RG   +K +   + PG   +         G PG  PG 
Sbjct: 427  PSEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPG-PPGT 485

Query: 979  QQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSS 1038
               +G        G       P    L  P    G  L+L   P   G   GG  + S  
Sbjct: 486  MGPTGQVGDPGERGPPGRPGLPGADGLPGPP---GTMLML---PFRFG---GGGDAGSKG 536

Query: 1039 PNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKA 1098
            P V                  S+     QA+++ +R  L        P G+  G  GP  
Sbjct: 537  PMV------------------SAQESQAQAILQQARLAL---RGPAGPMGL-TGRPGPVG 574

Query: 1099 PPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPG 1131
            PP + GL             G  G PG  G PG
Sbjct: 575  PPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPG 607



 Score = 40.0 bits (92), Expect = 0.015
 Identities = 73/295 (24%), Positives = 91/295 (30%), Gaps = 59/295 (20%)

Query: 872  GNPGSDYFPGGTAPGAPGPGGP--------SGTSSSGSKASGPPNPPAQGDGTSLSPNYT 923
            G PG    PG  A G PGP G          G   +GSK        +Q           
Sbjct: 499  GPPGRPGLPG--ADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLA 556

Query: 924  LESTSGNDGKPVSGG--GGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVS--PGQQ 979
            L   +G  G     G  G  G G  K + G V P              G PG +  PG++
Sbjct: 557  LRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGP-------QGPRGVQGPPGPAGKPGRR 609

Query: 980  QASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSSP 1039
                   G + +   RG P       T P   +G + L G   +     D G       P
Sbjct: 610  -------GRAGSDGARGMP-----GQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPP 657

Query: 1040 -NVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKA 1098
             + GE   D                  P+ L      P     PK PP        GP  
Sbjct: 658  GDDGERGDD--------------GEVGPRGL-PGEPGPRGLLGPKGPP--------GPPG 694

Query: 1099 PPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPPDEIHPL 1153
            PP   G+             G  G PG  G PG + +  P  + G  PP E  PL
Sbjct: 695  PPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIG--PPGEKGPL 747



 Score = 32.0 bits (71), Expect = 4.0
 Identities = 51/220 (23%), Positives = 76/220 (34%), Gaps = 27/220 (12%)

Query: 996  GAPTPHEKALTS------PSWGKGAELLLGD-QPDLIGSLDGGAKSDSSSPNVGEFASDE 1048
            GA  P   A TS      P  G+GA+ L G+   + I +LD         P     +  E
Sbjct: 373  GAEIPTSTADTSNSSNPAPPPGEGADDLEGEFTEETIRNLDENYYDPYYDPTS---SPSE 429

Query: 1049 VSTSY-ANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGI 1107
            +     AN+D +      P+        P +     + P  +  G  GP+ P    G   
Sbjct: 430  IGPGMPANQDTIYEGIGGPRGEKGQKGEPAI-----IEPGMLIEGPPGPEGPAGLPGPPG 484

Query: 1108 MSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSS---------SGAPPPDEIHPLEILQA 1158
                T      G  G PG PG PG + +  P  +          G     +   +   ++
Sbjct: 485  TMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQES 544

Query: 1159 QIQLQRQQFSISEDQPLGLKG--GKKGECAVGASGAQNGD 1196
            Q Q   QQ  ++   P G  G  G+ G      SG   G+
Sbjct: 545  QAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGE 584


>gi|22027597 alpha 1 type XIII collagen isoform 13 [Homo sapiens]
          Length = 690

 Score = 94.4 bits (233), Expect = 7e-19
 Identities = 152/561 (27%), Positives = 200/561 (35%), Gaps = 118/561 (21%)

Query: 681  QEPMRMPGEGHVPALPSPGLQFG-----GSLGGLGQLQSPG-AGVGLPSAASERRPPPPD 734
            + P   PG    PA   P  + G     G++G  G++ SPG AG+ +       R PP  
Sbjct: 109  EAPKTSPGCNCPPAFQGPTGRPGLPGDKGAIGMPGRVGSPGDAGLSIIGP----RGPPGQ 164

Query: 735  FATSALGGQPGFPFGAAGRQSTPHSGP----GVNSPPSAGGGGGSSGGGGGGGAYPPQPD 790
              T    G PG P G  G+    H GP    G+  PP   G  G  G  G  G YP +  
Sbjct: 165  PGTRGFPGFPG-PIGLDGKPG--HPGPKGDMGLTGPPGQPGPQGQKGEKGQCGEYPHR-- 219

Query: 791  FQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQN--MIASLGAPNLNVTF 848
                                             CL+++  A ++  +IA    P LN + 
Sbjct: 220  --------------------------------ECLSSMPAALRSSQIIALKLLPLLN-SV 246

Query: 849  NKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAP----GAPGPGGPSGTSSSGSKAS 904
                PP  KR+  Q E   A++ G PG    PG + P    G PGP GP G         
Sbjct: 247  RLAPPPVIKRRTFQGEQSQASIQGPPGPPGPPGPSGPLGHPGLPGPMGPPGLP------- 299

Query: 905  GPPNPPAQGDGTSLSPNYTLESTSGNDGKP----VSGGGGRGRGRRKRDSGHVSPGTFFD 960
            GPP P  +GD   +   +  +   G  G P      G  G      K + G   PGT  +
Sbjct: 300  GPPGP--KGD-PGIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEPG--IPGTKGE 354

Query: 961  KYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGD 1020
            K   A  S G PG+  GQ+   G A  G+S G  RG P P    L  P   KG   + G 
Sbjct: 355  K--GAEGSPGLPGLL-GQKGEKGDA--GNSIGGGRGEPGP--PGLPGPPGPKGEAGVDGQ 407

Query: 1021 -----QPDLIGSLDG-------GAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQA 1068
                 QP   G           G K     P  GE      + + A ++  + +   P  
Sbjct: 408  VGPPGQPGDKGERGAAGEQGPDGPKGSKGEPGKGEMVDYNGNINEALQEIRTLALMGPPG 467

Query: 1069 LVKASRSPLVTGSPK------LPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGG 1122
            L      P   G P       LP      GE GP+  P  +G              G  G
Sbjct: 468  LPGQIGPPGAPGIPGQKGEIGLPGPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKG 527

Query: 1123 GPGHPGTPGLEQVRTPTSSSGAPPPDEIHPLEILQAQIQLQRQQFSISEDQPLGLKG--G 1180
              GHPG+PG +  +  T  +G+P P    P                     P GL+G  G
Sbjct: 528  ENGHPGSPGEKGEKGETGQAGSPVPGLPGP----------------EGPPGPPGLQGVPG 571

Query: 1181 KKGECAV-GASGAQNGDSELG 1200
             KGE  + GA G +    E G
Sbjct: 572  PKGEAGLDGAKGEKGFQGEKG 592



 Score = 57.4 bits (137), Expect = 9e-08
 Identities = 141/552 (25%), Positives = 177/552 (32%), Gaps = 97/552 (17%)

Query: 271 PGASAMPRAAGMVGLSKMHAQPPQQQ------PQQQQQPQQQQQQHGVFFE--RFSGARK 322
           PG    P   G +GL      P  +       P  Q  PQ Q+ + G   E         
Sbjct: 165 PGTRGFPGFPGPIGLDGKPGHPGPKGDMGLTGPPGQPGPQGQKGEKGQCGEYPHRECLSS 224

Query: 323 MPVGLEPS---VGSRHPLMQPPQQAPPPPQQQPPQQPPQQQ--------PPPPPGLLVRQ 371
           MP  L  S        PL+   + APPP  ++   Q  Q Q        PP PPG     
Sbjct: 225 MPAALRSSQIIALKLLPLLNSVRLAPPPVIKRRTFQGEQSQASIQGPPGPPGPPG----- 279

Query: 372 NSCP---PALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFS 428
            S P   P LP P  G  G P      G P +   H        R   R M     P   
Sbjct: 280 PSGPLGHPGLPGPM-GPPGLPGPPGPKGDPGIQGYHG-------RKGERGM-----PGMP 326

Query: 429 MQHPPPQQAPNQRLQHFDAPPYMNVAKRPRF--DFPGSAGVDRCASWNGSMHNGALDNHL 486
            +H   + AP   +      P +   K  +     PG  G+       G   N       
Sbjct: 327 GKHGA-KGAPGIAVAGMKGEPGIPGTKGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGRG 385

Query: 487 SPSAYPGLPGEFTPPVPDSFPS-----GPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQ 541
            P   PGLPG   PP P          GPP Q P    +     +Q     +  + +  +
Sbjct: 386 EPGP-PGLPG---PPGPKGEAGVDGQVGPPGQ-PGDKGERGAAGEQGPDGPKGSKGEPGK 440

Query: 542 QQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNL-AQLGHPGDVGQGGLVHGGPVGGLAQ 600
            +          A   I+ +A       +  P L  Q+G PG  G  G    G +G    
Sbjct: 441 GEMVDYNGNINEALQEIRTLAL------MGPPGLPGQIGPPGAPGIPG--QKGEIGLPGP 492

Query: 601 PNFEREGGSTGA-GRLGTFEQQAPHLAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPH 659
           P  + E G  G  G +G    Q P          G +  PG   P   G  G     G  
Sbjct: 493 PGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGS--PGEKGEKGETGQAGSP 550

Query: 660 DPSL----APPPPPGGSGVLFRGPLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSP 715
            P L     PP PPG  GV   GP  E      +G           F G  G  G L  P
Sbjct: 551 VPGLPGPEGPPGPPGLQGV--PGPKGEAGLDGAKGEKG--------FQGEKGDRGPLGLP 600

Query: 716 GAG--VGLPSAASERRPPPPDFATSALGGQPGF--PFGAAGRQSTPHSGPGVNSPPSAGG 771
           G    +G+P  A  +             G PG   P GAAG        PG++ PP   G
Sbjct: 601 GTPGPIGVPGPAGPK-------GERGSKGDPGMTGPTGAAGL-------PGLHGPPGDKG 646

Query: 772 GGGSSGGGGGGG 783
             G  G  G  G
Sbjct: 647 NRGERGKKGSRG 658



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 140/556 (25%), Positives = 172/556 (30%), Gaps = 84/556 (15%)

Query: 632  FSGPHPPPGDLLPRRMGGSGLPADCG-PHDPSLA---PPPPPGGSGVL----FRGP--LQ 681
            F GP   PG  LP   G  G+P   G P D  L+   P  PPG  G      F GP  L 
Sbjct: 123  FQGPTGRPG--LPGDKGAIGMPGRVGSPGDAGLSIIGPRGPPGQPGTRGFPGFPGPIGLD 180

Query: 682  EPMRMPGEGHVPALPSPGLQFG--GSLGGLGQ---------LQSPGAGVG---------L 721
                 PG      L  P  Q G  G  G  GQ         L S  A +          L
Sbjct: 181  GKPGHPGPKGDMGLTGPPGQPGPQGQKGEKGQCGEYPHRECLSSMPAALRSSQIIALKLL 240

Query: 722  PSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGG 781
            P   S R  PPP        G+          Q++    PG   PP   G  G  G  G 
Sbjct: 241  PLLNSVRLAPPPVIKRRTFQGEQS--------QASIQGPPGPPGPPGPSGPLGHPGLPGP 292

Query: 782  GGAY----PPQPDFQPSQRTSASKLGALSL-GSFNKPSSKDNLFGQSCLAALSTACQNMI 836
             G      PP P   P  +    + G   + G   K  +K          A   A   M 
Sbjct: 293  MGPPGLPGPPGPKGDPGIQGYHGRKGERGMPGMPGKHGAK---------GAPGIAVAGMK 343

Query: 837  ASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGT 896
               G P        +  P     L Q    G A     G    PG   PG PGP GP G 
Sbjct: 344  GEPGIPGTKGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGRGEPG--PPGLPGPPGPKGE 401

Query: 897  SSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPG 956
            +    +  GPP  P        +     +   G+ G+P       G+G     +G+++  
Sbjct: 402  AGVDGQV-GPPGQPGDKGERGAAGEQGPDGPKGSKGEP-------GKGEMVDYNGNINEA 453

Query: 957  TFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAEL 1016
                +  A     G PG+ PGQ    GA       GE  G P P           KG   
Sbjct: 454  LQEIRTLALM---GPPGL-PGQIGPPGAPGIPGQKGEI-GLPGP-----PGHDGEKGPRG 503

Query: 1017 LLGDQ----PDLIGSLDG--GAKSDSSSPNVGEFASDEVSTSYANEDEVS-SSSDNPQAL 1069
              GD     P      DG  G K ++  P       ++  T  A          + P   
Sbjct: 504  KPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPVPGLPGPEGPPGP 563

Query: 1070 VKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGT 1129
                  P   G   L       G  G K     LGL         P   G  G  G  G 
Sbjct: 564  PGLQGVPGPKGEAGLDGAKGEKGFQGEKGDRGPLGLPGTPGPIGVPGPAGPKGERGSKGD 623

Query: 1130 PGLEQVRTPTSSSGAP 1145
            PG+     PT ++G P
Sbjct: 624  PGM---TGPTGAAGLP 636



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 84/371 (22%), Positives = 104/371 (28%), Gaps = 108/371 (29%)

Query: 579 GHPGDVGQGGLVH----GGPVGGLAQPNFEREGGSTGAGRLGTFEQQAPHLAQESAWFSG 634
           G PGD G+ G        GP G   +P         G G +  +        QE    + 
Sbjct: 412 GQPGDKGERGAAGEQGPDGPKGSKGEP---------GKGEMVDYNGNINEALQEIRTLAL 462

Query: 635 PHPP--PGDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHV 692
             PP  PG + P   G  G+P   G     +  P PPG  G   +GP  +P         
Sbjct: 463 MGPPGLPGQIGPP--GAPGIPGQKG----EIGLPGPPGHDGE--KGPRGKP--------- 505

Query: 693 PALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPP--PPDFATSALGGQPGFPFGA 750
                      G +G  G    PG   G P    E   P  P +       GQ G P   
Sbjct: 506 -----------GDMGPPGPQGPPGKD-GPPGVKGENGHPGSPGEKGEKGETGQAGSPVPG 553

Query: 751 AGRQSTPHSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSF 810
                 P   PG+   P   G  G  G  G  G    + D  P                 
Sbjct: 554 LPGPEGPPGPPGLQGVPGPKGEAGLDGAKGEKGFQGEKGDRGP----------------- 596

Query: 811 NKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNP--PEGKRKLSQNETDGA 868
                                       LG P          P  P+G+R          
Sbjct: 597 ----------------------------LGLPGTPGPIGVPGPAGPKGER---------- 618

Query: 869 AVAGNPGSDYFPGGT-APGAPGPGGPSGTSSS-GSKASGPPNPPAQGDGTSLSPNYTLES 926
              G+ G     G T A G PG  GP G   + G +       P    G   +P      
Sbjct: 619 ---GSKGDPGMTGPTGAAGLPGLHGPPGDKGNRGERGKKGSRGPKGDKGDQGAPGLDAPC 675

Query: 927 TSGNDGKPVSG 937
             G DG PV G
Sbjct: 676 PLGEDGLPVQG 686



 Score = 35.4 bits (80), Expect = 0.36
 Identities = 97/391 (24%), Positives = 125/391 (31%), Gaps = 53/391 (13%)

Query: 43  GPPGPVDPAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQP-VHGFFG--GQQPHH 99
           GPPGP  P+   LG P + G  M P G            G +  P + G+ G  G++   
Sbjct: 273 GPPGPPGPS-GPLGHPGLPGP-MGPPGLPG-------PPGPKGDPGIQGYHGRKGERGMP 323

Query: 100 GHPGSHHPHQHHPHFG--GNFGGPD-PGASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHM 156
           G PG H   +  P     G  G P  PG     G    G  G  G LG +    +    +
Sbjct: 324 GMPGKHGA-KGAPGIAVAGMKGEPGIPGTKGEKGAE--GSPGLPGLLGQKGEKGDAGNSI 380

Query: 157 AESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDSHS 216
              +G E   P  PG       +G      P P  P D+    AA   G     GS    
Sbjct: 381 GGGRG-EPGPPGLPGPPGPKGEAGVDGQVGP-PGQPGDKGERGAAGEQGPDGPKGSKGEP 438

Query: 217 LEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQL-PHYAAGRQVPGGAFPGASA 275
            +   V   G ++         A  G      P    GQ+ P  A G  +PG    G   
Sbjct: 439 GKGEMVDYNGNINEALQEIRTLALMG------PPGLPGQIGPPGAPG--IPGQK--GEIG 488

Query: 276 MPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERF---SGARKMPVGLEPSVG 332
           +P   G  G      +P    P   Q P  +    GV  E     S   K   G     G
Sbjct: 489 LPGPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAG 548

Query: 333 SRHPLMQPPQQAPPPPQQQPPQQPPQQQ-------------------PPPPPGLLVRQNS 373
           S  P +  P+  P PP  Q    P  +                    P   PG       
Sbjct: 549 SPVPGLPGPEGPPGPPGLQGVPGPKGEAGLDGAKGEKGFQGEKGDRGPLGLPGTPGPIGV 608

Query: 374 CPPALPRPQQGEAGTPSGGLQDGGPMLPSQH 404
             PA P+ ++G  G P      G   LP  H
Sbjct: 609 PGPAGPKGERGSKGDPGMTGPTGAAGLPGLH 639



 Score = 31.2 bits (69), Expect = 6.9
 Identities = 60/261 (22%), Positives = 87/261 (33%), Gaps = 41/261 (15%)

Query: 262 GRQVPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGAR 321
           GR  PG   PG    P   G  G+      P Q   + ++    +Q   G       G++
Sbjct: 383 GRGEPGP--PGLPGPPGPKGEAGVDGQVGPPGQPGDKGERGAAGEQGPDGP-----KGSK 435

Query: 322 KMPVGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSC----PPA 377
             P G    V     + +  Q+        PP  P Q  PP  PG+  ++       PP 
Sbjct: 436 GEP-GKGEMVDYNGNINEALQEIRTLALMGPPGLPGQIGPPGAPGIPGQKGEIGLPGPPG 494

Query: 378 L-----PRPQQGEAGTP---SGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSM 429
                 PR + G+ G P       +DG P +  ++     P  + E         PV  +
Sbjct: 495 HDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPVPGL 554

Query: 430 QHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPS 489
             P P+  P         PP +     P+    G AG+D      G            P 
Sbjct: 555 --PGPEGPP--------GPPGLQGVPGPK----GEAGLDGAKGEKGFQGE---KGDRGPL 597

Query: 490 AYPGLPGEFTPPVPDSFPSGP 510
             PG PG    P+    P+GP
Sbjct: 598 GLPGTPG----PIGVPGPAGP 614


>gi|22027580 alpha 1 type XIII collagen isoform 6 [Homo sapiens]
          Length = 702

 Score = 94.4 bits (233), Expect = 7e-19
 Identities = 152/561 (27%), Positives = 200/561 (35%), Gaps = 118/561 (21%)

Query: 681  QEPMRMPGEGHVPALPSPGLQFG-----GSLGGLGQLQSPG-AGVGLPSAASERRPPPPD 734
            + P   PG    PA   P  + G     G++G  G++ SPG AG+ +       R PP  
Sbjct: 109  EAPKTSPGCNCPPAFQGPTGRPGLPGDKGAIGMPGRVGSPGDAGLSIIGP----RGPPGQ 164

Query: 735  FATSALGGQPGFPFGAAGRQSTPHSGP----GVNSPPSAGGGGGSSGGGGGGGAYPPQPD 790
              T    G PG P G  G+    H GP    G+  PP   G  G  G  G  G YP +  
Sbjct: 165  PGTRGFPGFPG-PIGLDGKPG--HPGPKGDMGLTGPPGQPGPQGQKGEKGQCGEYPHR-- 219

Query: 791  FQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQN--MIASLGAPNLNVTF 848
                                             CL+++  A ++  +IA    P LN + 
Sbjct: 220  --------------------------------ECLSSMPAALRSSQIIALKLLPLLN-SV 246

Query: 849  NKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAP----GAPGPGGPSGTSSSGSKAS 904
                PP  KR+  Q E   A++ G PG    PG + P    G PGP GP G         
Sbjct: 247  RLAPPPVIKRRTFQGEQSQASIQGPPGPPGPPGPSGPLGHPGLPGPMGPPGLP------- 299

Query: 905  GPPNPPAQGDGTSLSPNYTLESTSGNDGKP----VSGGGGRGRGRRKRDSGHVSPGTFFD 960
            GPP P  +GD   +   +  +   G  G P      G  G      K + G   PGT  +
Sbjct: 300  GPPGP--KGD-PGIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEPG--IPGTKGE 354

Query: 961  KYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGD 1020
            K   A  S G PG+  GQ+   G A  G+S G  RG P P    L  P   KG   + G 
Sbjct: 355  K--GAEGSPGLPGLL-GQKGEKGDA--GNSIGGGRGEPGP--PGLPGPPGPKGEAGVDGQ 407

Query: 1021 -----QPDLIGSLDG-------GAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQA 1068
                 QP   G           G K     P  GE      + + A ++  + +   P  
Sbjct: 408  VGPPGQPGDKGERGAAGEQGPDGPKGSKGEPGKGEMVDYNGNINEALQEIRTLALMGPPG 467

Query: 1069 LVKASRSPLVTGSPK------LPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGG 1122
            L      P   G P       LP      GE GP+  P  +G              G  G
Sbjct: 468  LPGQIGPPGAPGIPGQKGEIGLPGPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKG 527

Query: 1123 GPGHPGTPGLEQVRTPTSSSGAPPPDEIHPLEILQAQIQLQRQQFSISEDQPLGLKG--G 1180
              GHPG+PG +  +  T  +G+P P    P                     P GL+G  G
Sbjct: 528  ENGHPGSPGEKGEKGETGQAGSPVPGLPGP----------------EGPPGPPGLQGVPG 571

Query: 1181 KKGECAV-GASGAQNGDSELG 1200
             KGE  + GA G +    E G
Sbjct: 572  PKGEAGLDGAKGEKGFQGEKG 592



 Score = 58.5 bits (140), Expect = 4e-08
 Identities = 137/548 (25%), Positives = 167/548 (30%), Gaps = 78/548 (14%)

Query: 632  FSGPHPPPGDLLPRRMGGSGLPADCG-PHDPSLA---PPPPPGGSGVL----FRGP--LQ 681
            F GP   PG  LP   G  G+P   G P D  L+   P  PPG  G      F GP  L 
Sbjct: 123  FQGPTGRPG--LPGDKGAIGMPGRVGSPGDAGLSIIGPRGPPGQPGTRGFPGFPGPIGLD 180

Query: 682  EPMRMPGEGHVPALPSPGLQFG--GSLGGLGQ---------LQSPGAGVG---------L 721
                 PG      L  P  Q G  G  G  GQ         L S  A +          L
Sbjct: 181  GKPGHPGPKGDMGLTGPPGQPGPQGQKGEKGQCGEYPHRECLSSMPAALRSSQIIALKLL 240

Query: 722  PSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGG 781
            P   S R  PPP        G+          Q++    PG   PP   G  G  G  G 
Sbjct: 241  PLLNSVRLAPPPVIKRRTFQGEQS--------QASIQGPPGPPGPPGPSGPLGHPGLPGP 292

Query: 782  GGAY----PPQPDFQPSQRTSASKLGALSL-GSFNKPSSKDNLFGQSCLAALSTACQNMI 836
             G      PP P   P  +    + G   + G   K  +K          A   A   M 
Sbjct: 293  MGPPGLPGPPGPKGDPGIQGYHGRKGERGMPGMPGKHGAK---------GAPGIAVAGMK 343

Query: 837  ASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGT 896
               G P        +  P     L Q    G A     G    PG   PG PGP GP G 
Sbjct: 344  GEPGIPGTKGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGRGEPG--PPGLPGPPGPKGE 401

Query: 897  SSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPG 956
            +    +  GPP  P        +     +   G+ G+P       G+G     +G+++  
Sbjct: 402  AGVDGQV-GPPGQPGDKGERGAAGEQGPDGPKGSKGEP-------GKGEMVDYNGNINEA 453

Query: 957  TFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAEL 1016
                +  A     G PG+ PGQ    GA       GE           L  P    G + 
Sbjct: 454  LQEIRTLALM---GPPGL-PGQIGPPGAPGIPGQKGEI---------GLPGPPGHDGEKG 500

Query: 1017 LLGDQPDLIGSLDGGAKSDSSSPNV-GEFASDEVSTSYANEDEVSSSSDNPQALVKASRS 1075
              G   D+      G       P V GE            + E   +      L      
Sbjct: 501  PRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPVPGLPGPEGP 560

Query: 1076 PLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQV 1135
            P   G   +P     AG  G K      G          P + G  G PG PGTPG   V
Sbjct: 561  PGPPGLQGVPGPKGEAGLDGAKGEKGFQGEKGDRGPLGLPGASGLDGRPGPPGTPGPIGV 620

Query: 1136 RTPTSSSG 1143
              P    G
Sbjct: 621  PGPAGPKG 628



 Score = 57.8 bits (138), Expect = 7e-08
 Identities = 144/558 (25%), Positives = 177/558 (31%), Gaps = 97/558 (17%)

Query: 271 PGASAMPRAAGMVGLSKMHAQPPQQQ------PQQQQQPQQQQQQHGVFFE--RFSGARK 322
           PG    P   G +GL      P  +       P  Q  PQ Q+ + G   E         
Sbjct: 165 PGTRGFPGFPGPIGLDGKPGHPGPKGDMGLTGPPGQPGPQGQKGEKGQCGEYPHRECLSS 224

Query: 323 MPVGLEPS---VGSRHPLMQPPQQAPPPPQQQPPQQPPQQQ--------PPPPPGLLVRQ 371
           MP  L  S        PL+   + APPP  ++   Q  Q Q        PP PPG     
Sbjct: 225 MPAALRSSQIIALKLLPLLNSVRLAPPPVIKRRTFQGEQSQASIQGPPGPPGPPG----- 279

Query: 372 NSCP---PALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFS 428
            S P   P LP P  G  G P      G P +   H        R   R M     P   
Sbjct: 280 PSGPLGHPGLPGPM-GPPGLPGPPGPKGDPGIQGYHG-------RKGERGM-----PGMP 326

Query: 429 MQHPPPQQAPNQRLQHFDAPPYMNVAKRPRF--DFPGSAGVDRCASWNGSMHNGALDNHL 486
            +H   + AP   +      P +   K  +     PG  G+       G   N       
Sbjct: 327 GKHGA-KGAPGIAVAGMKGEPGIPGTKGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGRG 385

Query: 487 SPSAYPGLPGEFTPPVPDSFPS-----GPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQ 541
            P   PGLPG   PP P          GPP Q P    +     +Q     +  + +  +
Sbjct: 386 EPGP-PGLPG---PPGPKGEAGVDGQVGPPGQ-PGDKGERGAAGEQGPDGPKGSKGEPGK 440

Query: 542 QQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNL-AQLGHPGDVGQGGLVHGGPVGGLAQ 600
            +          A   I+ +A       +  P L  Q+G PG  G  G    G +G    
Sbjct: 441 GEMVDYNGNINEALQEIRTLAL------MGPPGLPGQIGPPGAPGIPG--QKGEIGLPGP 492

Query: 601 PNFEREGGSTGA-GRLGTFEQQAPHLAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPH 659
           P  + E G  G  G +G    Q P          G +  PG   P   G  G     G  
Sbjct: 493 PGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGS--PGEKGEKGETGQAGSP 550

Query: 660 DPSL----APPPPPGGSGVLFRGPLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSP 715
            P L     PP PPG  GV   GP  E      +G           F G  G  G L  P
Sbjct: 551 VPGLPGPEGPPGPPGLQGV--PGPKGEAGLDGAKGEKG--------FQGEKGDRGPLGLP 600

Query: 716 GAGVGLPSAASERRPPPPDFATSALG--------GQPGF--PFGAAGRQSTPHSGPGVNS 765
           GA  GL         P P       G        G PG   P GAAG        PG++ 
Sbjct: 601 GAS-GLDGRPGPPGTPGPIGVPGPAGPKGERGSKGDPGMTGPTGAAGL-------PGLHG 652

Query: 766 PPSAGGGGGSSGGGGGGG 783
           PP   G  G  G  G  G
Sbjct: 653 PPGDKGNRGERGKKGSRG 670



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 98/378 (25%), Positives = 124/378 (32%), Gaps = 45/378 (11%)

Query: 579 GHPGDVGQGGLVHGGPVGGLAQPNFER--EGGSTGAGR--LGTFEQQAPHLAQESAWFSG 634
           G PG  G+ G      + GL     E+   G S G GR   G      P   +  A   G
Sbjct: 347 GIPGTKGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGRGEPGPPGLPGPPGPKGEAGVDG 406

Query: 635 PHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPA 694
              PPG   P   G  G   + GP  P  +   P  G  V + G + E ++   E    A
Sbjct: 407 QVGPPGQ--PGDKGERGAAGEQGPDGPKGSKGEPGKGEMVDYNGNINEALQ---EIRTLA 461

Query: 695 LPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALG--GQPGFPFGAAG 752
           L  P        G  GQ+  PGA  G+P    E   P P       G  G+PG   G  G
Sbjct: 462 LMGPP-------GLPGQIGPPGAP-GIPGQKGEIGLPGPPGHDGEKGPRGKPG-DMGPPG 512

Query: 753 RQSTP-HSGP----GVNSPPSAGGGGGSSGGGGGGGAYPPQ---PDFQPSQRTSASKLGA 804
            Q  P   GP    G N  P + G  G  G  G  G+  P    P+  P         G 
Sbjct: 513 PQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPVPGLPGPEGPPGPPGLQGVPGP 572

Query: 805 LSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNE 864
                 +    +    G+          +     LG P  +    +  PP     +    
Sbjct: 573 KGEAGLDGAKGEKGFQGE----------KGDRGPLGLPGASGLDGRPGPPGTPGPIGVPG 622

Query: 865 TDGAAVAGNPGSDYFPGGTAP----GAPGPGGPSGTSSS-GSKASGPPNPPAQGDGTSLS 919
             G    G  GS   PG T P    G PG  GP G   + G +       P    G   +
Sbjct: 623 PAGPK--GERGSKGDPGMTGPTGAAGLPGLHGPPGDKGNRGERGKKGSRGPKGDKGDQGA 680

Query: 920 PNYTLESTSGNDGKPVSG 937
           P        G DG PV G
Sbjct: 681 PGLDAPCPLGEDGLPVQG 698



 Score = 37.7 bits (86), Expect = 0.073
 Identities = 93/388 (23%), Positives = 123/388 (31%), Gaps = 62/388 (15%)

Query: 43  GPPGPV-DPAMSAL-GEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHG 100
           GPPGP  DP +    G     GM   P    A+G   +   G++ +P      G++   G
Sbjct: 300 GPPGPKGDPGIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEPGIPGTKGEKGAEG 359

Query: 101 HPGSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHMAESQ 160
            PG        P   G  G      + + GGR  G  G  G  G  PP  +G   +    
Sbjct: 360 SPGL-------PGLLGQKGEKGDAGNSIGGGR--GEPGPPGLPG--PPGPKGEAGVDGQV 408

Query: 161 GPESFGPQRPGNLPDFHSSGAS-------SHAVPAPCLPLDQSPN--------RAASFHG 205
           GP    P +PG+  +  ++G         S   P     +D + N        R  +  G
Sbjct: 409 GP----PGQPGDKGERGAAGEQGPDGPKGSKGEPGKGEMVDYNGNINEALQEIRTLALMG 464

Query: 206 LPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQL----PHYAA 261
            P   G       P     +G     E   PG  P GH     P    G +    P    
Sbjct: 465 PPGLPGQIGPPGAPGIPGQKG-----EIGLPG--PPGHDGEKGPRGKPGDMGPPGPQGPP 517

Query: 262 GRQVPGGAFPGASAMPRAAGMVGLSKMHAQ-----PPQQQPQQQQQPQQQQQQHGVFFER 316
           G+  P G   G +  P + G  G      Q     P    P+    P   Q   G   E 
Sbjct: 518 GKDGPPGV-KGENGHPGSPGEKGEKGETGQAGSPVPGLPGPEGPPGPPGLQGVPGPKGEA 576

Query: 317 FSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPP 376
                K   G +   G R PL  P            P  P    P   PG         P
Sbjct: 577 GLDGAKGEKGFQGEKGDRGPLGLPGASG----LDGRPGPPGTPGPIGVPG---------P 623

Query: 377 ALPRPQQGEAGTPSGGLQDGGPMLPSQH 404
           A P+ ++G  G P      G   LP  H
Sbjct: 624 AGPKGERGSKGDPGMTGPTGAAGLPGLH 651



 Score = 35.0 bits (79), Expect = 0.48
 Identities = 91/352 (25%), Positives = 118/352 (33%), Gaps = 54/352 (15%)

Query: 43  GPPGPVDPAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQP-VHGFFG--GQQPHH 99
           GPPGP  P+   LG P + G  M P G            G +  P + G+ G  G++   
Sbjct: 273 GPPGPPGPS-GPLGHPGLPGP-MGPPGLPG-------PPGPKGDPGIQGYHGRKGERGMP 323

Query: 100 GHPGSHHPHQHHPHFG--GNFGGPD-PGASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHM 156
           G PG H   +  P     G  G P  PG     G    G  G  G LG +    +    +
Sbjct: 324 GMPGKHGA-KGAPGIAVAGMKGEPGIPGTKGEKGAE--GSPGLPGLLGQKGEKGDAGNSI 380

Query: 157 AESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDSHS 216
              +G E   P  PG       +G      P P  P D+    AA   G     GS    
Sbjct: 381 GGGRG-EPGPPGLPGPPGPKGEAGVDGQVGP-PGQPGDKGERGAAGEQGPDGPKGSKGEP 438

Query: 217 LEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQL-PHYAAGRQVPGGAFPGASA 275
            +   V   G ++         A  G      P    GQ+ P  A G  +PG    G   
Sbjct: 439 GKGEMVDYNGNINEALQEIRTLALMG------PPGLPGQIGPPGAPG--IPGQK--GEIG 488

Query: 276 MPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRH 335
           +P   G  G      +P    P   Q P  +    GV  E          G   S G + 
Sbjct: 489 LPGPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKGEN---------GHPGSPGEKG 539

Query: 336 PLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQGEAG 387
              +  Q   P P    P+ P     P PPGL          +P P +GEAG
Sbjct: 540 EKGETGQAGSPVPGLPGPEGP-----PGPPGL--------QGVPGP-KGEAG 577


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score = 94.0 bits (232), Expect = 9e-19
 Identities = 283/1163 (24%), Positives = 360/1163 (30%), Gaps = 255/1163 (21%)

Query: 43   GPPGPVDPAMSA--LGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFG-----GQ 95
            G PGP+ P  S    G P   G + EP     R  +    G   +    GF G     G 
Sbjct: 243  GDPGPMGPIGSRGPEGPPGKPGEDGEP----GRNGNPGEVGFAGSPGARGFPGAPGLPGL 298

Query: 96   QPHHGHPGSHHPHQH--HPHFGGNFGGPDP-GASCLHGGRLLGYGGAAGGLGSQ-PPFAE 151
            + H GH G   P      P   G  G   P GA    G R  G  G  G LG Q  P   
Sbjct: 299  KGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPR--GMPGERGRLGPQGAPGQR 356

Query: 152  GYEHMAESQGP--------ESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASF 203
            G   M    GP         S  P  PG   +   +GA     P         P    S 
Sbjct: 357  GAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGS- 415

Query: 204  HGLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPG-EAPSGHFDMFSPSDSEGQLPHYAAG 262
             GLP + G+D                      PG + P+G      P  S G        
Sbjct: 416  PGLPGAIGTDGT--------------------PGAKGPTGSPGTSGPPGSAGP------- 448

Query: 263  RQVPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARK 322
               PG   P  S  P+     G+      P     + +  P+ +   HG+         +
Sbjct: 449  ---PGSPGPQGSTGPQ-----GIRGQPGDPGVPGFKGEAGPKGEPGPHGI---------Q 491

Query: 323  MPVGLEPSVGSRHPLMQPPQQAPPPP--QQQPPQQ---PPQQQPPPPPGLLVRQNSCPPA 377
             P+G     G R P   P    PP P  ++  P     P     P P G    +     +
Sbjct: 492  GPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSS 551

Query: 378  LPRPQQGEAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQA 437
             P+  QG+ G P      G P LP        P  +     + P   P    +  PP   
Sbjct: 552  GPKGSQGDPGRP------GEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSI 605

Query: 438  PNQRLQHFDAPPYMNV-AKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPG 496
              +       P  M +   +     PG  G    A   G       D  + PS   G PG
Sbjct: 606  GIR-----GQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPG 660

Query: 497  ------EFTPPVPDSF-----PSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQ 545
                  E  PP P  F     P GPP +   P  Q +            + ++    ++ 
Sbjct: 661  LAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERG 720

Query: 546  QQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGL--------VHGGPV-- 595
            +            K MA  +     +  +    G PGD G  GL        + G P   
Sbjct: 721  EPGITGLPGE---KGMAGGHGPDGPKG-SPGPSGTPGDTGPPGLQGMPGERGIAGTPGPK 776

Query: 596  ---GGLAQPNFEREGGSTGA-GRLGTFEQQAPHLAQESAWFSGPHPPPGDLLPRRM---- 647
               GG+ +   E   G+ GA G  G      P         +GP    G+  PR +    
Sbjct: 777  GDRGGIGEKGAEGTAGNDGARGLPGPLGPPGP---------AGPTGEKGEPGPRGLVGPP 827

Query: 648  GGSGLPADCGPHDPSLA-----PPPPPGGSGVLFRGPLQEPMRM-----PGEGHVPALPS 697
            G  G P   G + P+ A     P  P G  GV  +G   EP +      PG   +   P 
Sbjct: 828  GSRGNPGSRGENGPTGAVGFAGPQGPDGQPGV--KGEPGEPGQKGDAGSPGPQGLAGSPG 885

Query: 698  PGLQFG--GSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALGGQPGFPFGAAGRQS 755
            P    G  G  GG G    PGA  G P +A    PP P        G PG P G  G   
Sbjct: 886  PHGPNGVPGLKGGRGTQGPPGA-TGFPGSAGRVGPPGP-------AGAPG-PAGPLGE-- 934

Query: 756  TPHSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSS 815
                 PG   PP   G  GS G  G  G  P  P   P  +                   
Sbjct: 935  -----PGKEGPPGLRGDPGSHGRVGDRG--PAGPPGGPGDK------------------- 968

Query: 816  KDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPG 875
                                    G P  +       PP       Q       + G PG
Sbjct: 969  ------------------------GDPGEDGQPGPDGPPGPAGTTGQR-----GIVGMPG 999

Query: 876  SDYFPGGTAPGAPGPGGPSG----TSSSGSKASGPPNP--PAQGDGTSLSPNYTLESTSG 929
                 G   PG PGP G  G    T ++G K  GPP P  P   +G    P    E  +G
Sbjct: 1000 QRGERG--MPGLPGPAGTPGKVGPTGATGDK--GPPGPVGPPGSNGPVGEPGP--EGPAG 1053

Query: 930  NDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGS 989
            NDG P   G    RG    D G   P       +  P S GAPG +PG   A G A    
Sbjct: 1054 NDGTPGRDGAVGERG----DRGDPGP-------AGLPGSQGAPG-TPGPVGAPGDAGQRG 1101

Query: 990  SAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEV 1049
              G +RG   P  +A        G   L G Q       D G + D        F   + 
Sbjct: 1102 DPG-SRGPIGPPGRA--------GKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQG 1152

Query: 1050 STSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVG-AGEHGPKAPPPALGLGIM 1108
                   +    S+  P               P+ PP  VG +G+ G   P   +G   +
Sbjct: 1153 LPGPPGPNGEQGSAGIPGPF-----------GPRGPPGPVGPSGKEGNPGPLGPIGPPGV 1201

Query: 1109 SNSTSTPDSYGGGGGPGHPGTPG 1131
              S       G  G PG PG PG
Sbjct: 1202 RGSVGEAGPEGPPGEPGPPGPPG 1224



 Score = 85.1 bits (209), Expect = 4e-16
 Identities = 176/680 (25%), Positives = 222/680 (32%), Gaps = 116/680 (17%)

Query: 579  GHPGDVGQGGLVH--GGPVGGLAQPNFEREGGSTGAGRLGTFEQQAPHLAQESAWFSGPH 636
            GHP   G  GL       + GL + +          G +G    + P   Q     +GP 
Sbjct: 177  GHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPT 236

Query: 637  PPPGDLLPRRMGGSGLPADCGPHDP--SLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPA 694
             PPG+           P D GP  P  S  P  PPG  G        EP R    G V  
Sbjct: 237  GPPGE-----------PGDPGPMGPIGSRGPEGPPGKPG-----EDGEPGRNGNPGEVGF 280

Query: 695  LPSPGLQ-FGGSLG--------GLGQLQSPGAGVGLPSAASERRPPPPDFATSALG--GQ 743
              SPG + F G+ G        G   L+ P   VG P +  E  P  P  A   LG  G 
Sbjct: 281  AGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGM 340

Query: 744  PGF-----PFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTS 798
            PG      P GA G++   H  PG   P    G  GSSG  G            P  +  
Sbjct: 341  PGERGRLGPQGAPGQRGA-HGMPGKPGPMGPLGIPGSSGFPGN-----------PGMKGE 388

Query: 799  ASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKR 858
            A   GA        P       G++               +G+P L         P  K 
Sbjct: 389  AGPTGARG------PEGPQGQRGET----------GPPGPVGSPGLPGAIGTDGTPGAKG 432

Query: 859  KLSQNETDGA-AVAGNPGSDYFPGGTAP----GAPG-PGGPSGTSSSGSKAS-------G 905
                  T G    AG PGS    G T P    G PG PG P     +G K         G
Sbjct: 433  PTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQG 492

Query: 906  PPNPPAQ-------GDGTSLSPNYTL--ESTSGNDGKPVSGG--GGRGRGRRKRDSGHVS 954
            P  PP +       GD  ++ P   +      GN G P S G  G +G    +   G   
Sbjct: 493  PIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSG 552

Query: 955  P-GTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKG 1013
            P G+  D     P   G PG+ PG +  +G        G+      P E     P    G
Sbjct: 553  PKGSQGD-----PGRPGEPGL-PGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIG 606

Query: 1014 AELLLGDQPDLIGSLDG--GAKSDSSSPNVGEFASDEVSTSYANED-EVSSSSD-NPQAL 1069
                +  QP  +G L G  G+  D   P     A          +D EV  S    P  L
Sbjct: 607  ----IRGQPGSMG-LPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGL 661

Query: 1070 V--KASRSPL-------VTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGG 1120
               +  + P        + G P  P  G   G+ G    P A+G          P   G 
Sbjct: 662  AGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGE 721

Query: 1121 GGGPGHPGTPGLEQVRTPTSSSGAPPPDEIHPLEILQAQIQLQRQQFSISEDQPLGLKGG 1180
             G  G PG  G+     P    G+P P    P +     +Q    +  I+     G KG 
Sbjct: 722  PGITGLPGEKGMAGGHGPDGPKGSPGPSGT-PGDTGPPGLQGMPGERGIAGTP--GPKGD 778

Query: 1181 KKGECAVGASGAQNGDSELG 1200
            + G    GA G    D   G
Sbjct: 779  RGGIGEKGAEGTAGNDGARG 798



 Score = 82.4 bits (202), Expect = 3e-15
 Identities = 233/930 (25%), Positives = 288/930 (30%), Gaps = 146/930 (15%)

Query: 324  PVGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQ 383
            P GL+   G   P   P +   P P      + P+  PP  PG    ++  P     P +
Sbjct: 223  PQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEG-PPGKPG----EDGEPGRNGNPGE 277

Query: 384  -GEAGTPSGGLQDGGPMLPSQ-----HAQFEYPIHRLENRSMHPYSEPVFSMQ------- 430
             G AG+P      G P LP       H   E P   +        + P   M        
Sbjct: 278  VGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGP 337

Query: 431  --------HPPPQQAPNQRLQHF--DAPPYMNVAKRPRFD-FPGSAGVDRCASWNGSMHN 479
                       PQ AP QR  H     P  M     P    FPG+ G+   A   G+   
Sbjct: 338  RGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGP 397

Query: 480  GALDNHLS------PSAYPGLPGEF----TP----PVPDSFPSGPPLQHPAPDHQSLQQQ 525
                          P   PGLPG      TP    P      SGPP     P     Q  
Sbjct: 398  EGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGS 457

Query: 526  QQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVG 585
               Q  + Q         + +   + +     I+       ++  R P     G PG VG
Sbjct: 458  TGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPR----GDPGTVG 513

Query: 586  QGGLVHGGPVGGLAQPNFEREGGSTGA-GRLGTFEQQAPHLAQESAWFSGPHPPPGDL-L 643
              G     PVG    P      GS G  G  G   ++ P  +       G    PG+  L
Sbjct: 514  PPG-----PVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGL 568

Query: 644  PRRMGGSGLPADCGPHD---PSLAP-----PPPPGGSGVLFRGPLQEPMRMPGEGHVPAL 695
            P   G +G P   GP     P  AP     P PPG  G+  RG     M +PG       
Sbjct: 569  PGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGI--RGQ-PGSMGLPGPKGSSGD 625

Query: 696  PS-PGLQFGGSLGGLGQLQSPGAG--------VGLPSAASER--RPPPPDFATSALGGQP 744
            P  PG    G+ G  GQ  +PG          VG P  A ER  + PP       L G P
Sbjct: 626  PGKPGE--AGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPP 683

Query: 745  GFPF--GAAGRQSTP--------------HSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQ 788
            G P   G  G Q  P                 PG    P   G  G  G  GG G  P  
Sbjct: 684  GPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHG--PDG 741

Query: 789  PDFQPSQRTSASKLGALSL-------GSFNKPSSKDNLFGQSCLAALSTA----CQNMIA 837
            P   P    +    G   L       G    P  K +  G     A  TA     + +  
Sbjct: 742  PKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPG 801

Query: 838  SLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGTS 897
             LG P       +K  P G R L           GNPGS    G T  GA G  GP G  
Sbjct: 802  PLGPPGPAGPTGEKGEP-GPRGL----VGPPGSRGNPGSRGENGPT--GAVGFAGPQGPD 854

Query: 898  SSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGT 957
                    P  P  +GD  S  P     S   +    V G  G GRG +        PG+
Sbjct: 855  GQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKG-GRGTQGPPGATGFPGS 913

Query: 958  FFDKYSAAPDSGGAPGVS-----PGQQQASG--------AAVGGSSAGETRGAP----TP 1000
                    P   GAPG +     PG++   G          VG        G P     P
Sbjct: 914  A--GRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDP 971

Query: 1001 HEKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASD--EVSTSYANEDE 1058
             E     P    G     G Q  ++G    G + +   P +   A    +V  + A  D+
Sbjct: 972  GEDGQPGPDGPPGPAGTTG-QRGIVGM--PGQRGERGMPGLPGPAGTPGKVGPTGATGDK 1028

Query: 1059 -----VSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTS 1113
                 V     N          P   G+   P R    GE G +  P   GL     +  
Sbjct: 1029 GPPGPVGPPGSNGPVGEPGPEGP--AGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPG 1086

Query: 1114 TPDSYGGGGGPGHPGTPGLEQVRTPTSSSG 1143
            TP   G  G  G  G PG      P   +G
Sbjct: 1087 TPGPVGAPGDAGQRGDPGSRGPIGPPGRAG 1116



 Score = 80.5 bits (197), Expect = 1e-14
 Identities = 157/646 (24%), Positives = 199/646 (30%), Gaps = 122/646 (18%)

Query: 579  GHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGA----GRLGTFEQQAPHLAQESAWFSG 634
            G PG  G  G    GP G         + G  G     G  G   +  PH  Q      G
Sbjct: 441  GPPGSAGPPG--SPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQ------G 492

Query: 635  PHPPPGDLLPRRMGGSGLPADCGPHDP--------------SLAPPPPPGGSGVLFRGPL 680
            P  PPG+    + G  G P   GP  P              S   P P G  G   RGP+
Sbjct: 493  PIGPPGE--EGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGE--RGPV 548

Query: 681  QEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGVG-LPSAASERRPPPPDFATSA 739
                    +G       PGL     L G   +Q P   +G L +   + RP PP   +  
Sbjct: 549  GSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPP--GSIG 606

Query: 740  LGGQPGF-----PFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPS 794
            + GQPG      P G++G    P        P   G  G     G  G   PP    +  
Sbjct: 607  IRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERG 666

Query: 795  QRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPP 854
            ++      G   L     P  +    G   +     A    +  LG             P
Sbjct: 667  EQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGA----VGPLG-------------P 709

Query: 855  EGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAP-GPGGPSGTSSSGSKASGPPN----- 908
             G+R  +  E     + G PG     GG  P  P G  GPSGT       +GPP      
Sbjct: 710  RGERG-NPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGD----TGPPGLQGMP 764

Query: 909  --------PPAQGDGTSLSPNYTLESTSGNDGK--------PVSGGGGRGRGRRKRDSGH 952
                    P  +GD   +      E T+GNDG         P    G  G        G 
Sbjct: 765  GERGIAGTPGPKGDRGGIGEKGA-EGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGL 823

Query: 953  VSPGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAP----TPHEKALTSP 1008
            V P          P S G PG S G+   +GA VG +      G P     P E      
Sbjct: 824  VGP----------PGSRGNPG-SRGENGPTGA-VGFAGPQGPDGQPGVKGEPGEPGQKGD 871

Query: 1009 SWGKGAELLLGDQ----PDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSS- 1063
            +   G + L G      P+ +  L GG +     P    F                  + 
Sbjct: 872  AGSPGPQGLAGSPGPHGPNGVPGLKGG-RGTQGPPGATGFPGSAGRVGPPGPAGAPGPAG 930

Query: 1064 -------DNPQALV--KASRSPLVTGSPKLPPRGVGA-------GEHGPKAPPPALGLGI 1107
                   + P  L     S   +    P  PP G G        G+ GP  PP   G   
Sbjct: 931  PLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTG 990

Query: 1108 MSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSG-APPPDEIHP 1152
                   P   G  G PG PG  G      PT ++G   PP  + P
Sbjct: 991  QRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGP 1036



 Score = 75.5 bits (184), Expect = 3e-13
 Identities = 162/672 (24%), Positives = 213/672 (31%), Gaps = 147/672 (21%)

Query: 577  QLGHPGDVGQGGLVHG-----GPVGGLAQPNFEREGGSTGA-GRLGTFEQQAPHLAQESA 630
            +LG  G  GQ G  HG     GP+G L  P      G+ G  G  G    + P   Q   
Sbjct: 346  RLGPQGAPGQRG-AHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQR 404

Query: 631  WFSGPHPPPGDL-LPRRMGGSGLPADCGPH-DPSLAPPP----PPGGSGVLFRGPLQEPM 684
              +GP  P G   LP  +G  G P   GP   P  + PP    PPG  G       Q   
Sbjct: 405  GETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIR 464

Query: 685  RMPGEGHVPALPSPGLQFGGSLGGLGQ-----LQSPGAGVGLPSAASERRP--------P 731
              PG+  VP        F G  G  G+     +Q P   +G P    +R P        P
Sbjct: 465  GQPGDPGVPG-------FKGEAGPKGEPGPHGIQGP---IGPPGEEGKRGPRGDPGTVGP 514

Query: 732  PPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDF 791
            P         G  GFP G+ G    P    G   P  + G  GS G  G  G  P  P  
Sbjct: 515  PGPVGERGAPGNRGFP-GSDGLPG-PKGAQGERGPVGSSGPKGSQGDPGRPGE-PGLPGA 571

Query: 792  Q-----PSQRTSASKLGALSL-GSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLN 845
            +     P  +    KLG L   G   +P    ++             +    S+G P   
Sbjct: 572  RGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSI-----------GIRGQPGSMGLPGPK 620

Query: 846  VTFNKKNPPEGKRKLSQNETDGAAVAGN---PGSDYFPGGTAPGAP----------GPGG 892
             +      P         E   A V G    PG D   G + P  P          GP G
Sbjct: 621  GSSGDPGKP--------GEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPG 672

Query: 893  PSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGH 952
            P+G         GPP PP +G               G  G P + G    RG R      
Sbjct: 673  PTGFQG----LPGPPGPPGEGGKPG---------DQGVPGDPGAVGPLGPRGERGNPGER 719

Query: 953  VSPGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAP----TPHEKALTSP 1008
              PG      +  P   G  G   G     G+     + G+T G P     P E+ +   
Sbjct: 720  GEPGI-----TGLPGEKGMAG-GHGPDGPKGSPGPSGTPGDT-GPPGLQGMPGERGIAGT 772

Query: 1009 SWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQA 1068
               KG    +G++       +G A +D +    G       +     + E       P+ 
Sbjct: 773  PGPKGDRGGIGEK-----GAEGTAGNDGARGLPGPLGPPGPAGPTGEKGE-----PGPRG 822

Query: 1069 LVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPG 1128
            LV    S    G+P         G  G   P  A+G          P   G  G PG  G
Sbjct: 823  LVGPPGS---RGNP---------GSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKG 870

Query: 1129 TPGLEQVRTPTSSSGAPPPDEIHPLEILQAQIQLQRQQFSISEDQPLGLKGGKKGECAVG 1188
              G      P   +G+P P   + +                      GLKGG+  +   G
Sbjct: 871  DAGSP---GPQGLAGSPGPHGPNGVP---------------------GLKGGRGTQGPPG 906

Query: 1189 ASGAQNGDSELG 1200
            A+G       +G
Sbjct: 907  ATGFPGSAGRVG 918



 Score = 61.2 bits (147), Expect = 6e-09
 Identities = 145/566 (25%), Positives = 178/566 (31%), Gaps = 144/566 (25%)

Query: 607  GGSTGAGRLGTFEQQAPHLAQESAWFSG---PHPPPGDLLPR-RMGGSGLPADCGPHDPS 662
            GG+T  GR    ++  P L        G   P  PPG   PR   G  G P   GP    
Sbjct: 102  GGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGPQGID 161

Query: 663  LAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPALPSP-GLQ--FGGSLGGLGQLQSPGAGV 719
               P  PG  G             PG    P+ P P GL   F   + GL +    G+ V
Sbjct: 162  -GEPGVPGQPGA------------PGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQV 208

Query: 720  GL-PSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGG 778
            GL P +     P  P      L GQ G              G G   PP   G  G  G 
Sbjct: 209  GLMPGSVGPVGPRGPQ----GLQGQQG--------------GAGPTGPPGEPGDPGPMGP 250

Query: 779  GGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIAS 838
             G  G  P  P  +P              G   +P    N  G+   A  S   +    +
Sbjct: 251  IGSRG--PEGPPGKP--------------GEDGEPGRNGNP-GEVGFAG-SPGARGFPGA 292

Query: 839  LGAPNLNVTFNKKN--PPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAP-GAPGPGGPSG 895
             G P L      K    P+G+              G PGS    G T P GA GP GP G
Sbjct: 293  PGLPGLKGHRGHKGLEGPKGE-------------VGAPGSKGEAGPTGPMGAMGPLGPRG 339

Query: 896  TSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSP 955
                  +  GP   P Q                G  GKP                G + P
Sbjct: 340  MPGERGRL-GPQGAPGQ------------RGAHGMPGKP----------------GPMGP 370

Query: 956  GTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPH-EKALTSPSWGKGA 1014
                      P S G PG +PG +  +G           RG   P  ++  T P    G+
Sbjct: 371  -------LGIPGSSGFPG-NPGMKGEAGPT-------GARGPEGPQGQRGETGPPGPVGS 415

Query: 1015 ELLLGDQPDLIGSLDG--GAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKA 1072
              L    P  IG+ DG  GAK  + SP      S    ++          S  PQ +   
Sbjct: 416  PGL----PGAIGT-DGTPGAKGPTGSPGT----SGPPGSAGPPGSPGPQGSTGPQGIRGQ 466

Query: 1073 SRSPLVTG-----SPKLPPRGVGA----------GEHGPKAPPPALGLGIMSNSTSTPDS 1117
               P V G      PK  P   G           G+ GP+  P  +G          P +
Sbjct: 467  PGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGN 526

Query: 1118 YGGGGGPGHPGTPGLEQVRTPTSSSG 1143
             G  G  G PG  G +  R P  SSG
Sbjct: 527  RGFPGSDGLPGPKGAQGERGPVGSSG 552



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 76/236 (32%), Positives = 90/236 (38%), Gaps = 47/236 (19%)

Query: 579  GHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGA-GRLGTFEQQAPHLAQESAWFSGPHP 637
            G PG VG  G    GPVG   +P  E   G+ G  GR G   ++        A   G   
Sbjct: 1029 GPPGPVGPPG--SNGPVG---EPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQG 1083

Query: 638  PPGDLLPRRMGGSGLPADCGPH-DP-SLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPAL 695
             PG       G  G P D G   DP S  P  PPG +G   RG       +PG    P  
Sbjct: 1084 APGT-----PGPVGAPGDAGQRGDPGSRGPIGPPGRAGK--RG-------LPG----PQG 1125

Query: 696  PSPGLQFGGSLGGLGQLQSPG-AGV-GLPSAASERRPPPPDFATSALG--------GQPG 745
            P       G  G  GQ    G  G+ GLP       PP P+    + G        G PG
Sbjct: 1126 PRGDKGDHGDRGDRGQKGHRGFTGLQGLPG------PPGPNGEQGSAGIPGPFGPRGPPG 1179

Query: 746  FPFGAAGRQSTPHSGP-GVNSPPSAGGGGGSSG-GGGGGGAYPPQPDFQPSQRTSA 799
             P G +G++  P  GP G   PP   G  G +G  G  G   PP P   P   T+A
Sbjct: 1180 -PVGPSGKEGNP--GPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPGHLTAA 1232



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 38/132 (28%), Positives = 51/132 (38%), Gaps = 11/132 (8%)

Query: 1076 PLVTG-----SPKLPPRGVGA-GEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGT 1129
            P+VTG      P  PP   G  GE GPK  P   G   +      P   G  G PGHP  
Sbjct: 122  PVVTGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSH 181

Query: 1130 PGLEQVRTPTSSSGAPPPDEIHPLEILQAQIQLQRQQFS-ISEDQPLGLKGGKKGECAVG 1188
            PG + +  P S+  A   ++      L +Q+ L       +    P GL+G + G    G
Sbjct: 182  PGPDGLSRPFSAQMAGLDEK----SGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTG 237

Query: 1189 ASGAQNGDSELG 1200
              G       +G
Sbjct: 238  PPGEPGDPGPMG 249


>gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]
          Length = 1690

 Score = 93.2 bits (230), Expect = 1e-18
 Identities = 294/1198 (24%), Positives = 372/1198 (31%), Gaps = 216/1198 (18%)

Query: 42   GGPPGPVDPAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHGH 101
            GGP GP        GEP ++G   +P     +G+  +   G    P      G+    G 
Sbjct: 204  GGPAGPTGYP----GEPGLVGPPGQPGRPGLKGNPGVGVKGQMGDP------GEVGQQGS 253

Query: 102  PGSH---HPHQHHPHFG--------GNFGGPDP-------GASCLHGGRLLGYGGAAGGL 143
            PG      P     + G        G  G P P       G        + G+ G  G  
Sbjct: 254  PGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKGESGIGAKGEKGIPGFPGPRGDP 313

Query: 144  GS--QPPFAEGYEHMAESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAA 201
            GS   P F      +     P  FG   P   P           +  P LPL   P    
Sbjct: 314  GSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPGNRGHPGPPGVLVTPPLPLKGPPGDP- 372

Query: 202  SFHGLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAA 261
               G P   G       P      G         PGEA +G      P    G LP    
Sbjct: 373  ---GFPGRYGETGDVGPPGPPGLLGR--------PGEACAGMIGPPGPQGFPG-LPGLPG 420

Query: 262  GRQVPG--GAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSG 319
               +PG   + PG    P + G+ G   +   P                  G      S 
Sbjct: 421  EAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLP------------------GSSVIYCSV 462

Query: 320  ARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQPPQ----QPPQQQPPPPPGLLVRQNSCP 375
                P G++  VG       PP    P  ++        +P    PP PPGL  RQ S  
Sbjct: 463  GNPGPQGIKGKVG-------PPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKG 515

Query: 376  PALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQ 435
                    G  G P     +G P LP +H     P ++     M      V  ++    +
Sbjct: 516  DLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDM-----VVSRVKGHKGE 570

Query: 436  QAPNQRLQHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLP 495
            + P       D PP            PGS G D  A   G           +P    G P
Sbjct: 571  RGP-------DGPPGFPGQ-------PGSHGRDGHAGEKGDPGPPGDHEDATPGG-KGFP 615

Query: 496  GEFTPPVPDSFPSGPP-LQHPAPD----HQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 550
            G   PP   + P GPP L  P P     H  +      +     + Q+            
Sbjct: 616  GPLGPP-GKAGPVGPPGLGFPGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPG 674

Query: 551  RQNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGST 610
            R            +        P L+  G  G  G+ G      + G   P F  + G  
Sbjct: 675  RHGPPGFDGPPGPKGFPGPQGAPGLS--GSDGHKGRPGTPGTAEIPG--PPGFRGDMGDP 730

Query: 611  GAGRLGTFEQQAPHLAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPPPPG 670
            G G             ++ +   GP  PPG   P   G  G+P D  P    L PP   G
Sbjct: 731  GFG------------GEKGSSPVGPPGPPGS--PGVNGQKGIPGD--PAFGHLGPPGKRG 774

Query: 671  GSGVL-FRGPLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERR 729
             SGV   +GP  +P     EG  PA     L   G  G  G    PG   G P  + ER 
Sbjct: 775  LSGVPGIKGPRGDPGCPGAEG--PAGIPGFLGLKGPKGREGHAGFPGVP-GPPGHSCERG 831

Query: 730  PPPPDFATSALGGQPGFPFGAAGRQSTP--HSGPGVNSPPSAGGGGGSSGGGGGGGAYPP 787
             P        + GQPG P G  G    P     PG   PP   G  G  G  G  GA+ P
Sbjct: 832  AP-------GIPGQPGLP-GYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGP 883

Query: 788  Q----------PDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIA 837
                        D  P         G      F  P  +     + C  A     +  ++
Sbjct: 884  PGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGF--PGERGKPGAEGCPGAKGEPGEKGMS 941

Query: 838  SL-GAPNLNVTFNKKNPP--EGKRKL-SQNETDGAAVAGNPGSDYFPG-----GTAP--- 885
             L G   L        PP  EG+  + SQ  T G    G PG D FPG     GT     
Sbjct: 942  GLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEP--GPPGDDGFPGERGDKGTPGMQG 999

Query: 886  --GAPGPGGPSG--TSSSGSKAS-GPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGG-- 938
              G PG  GP G      G K   GPP PP     T L          G+ G+P S G  
Sbjct: 1000 RRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPP 1059

Query: 939  ------GGRG-RGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVS--PGQQQASGAAVGGS 989
                  G RG +G +   + H  P          P   G PG    PG   ASG   G  
Sbjct: 1060 GFSGIDGARGPKGNKGDPASHFGP----------PGPKGEPGSPGCPGHFGASGEQ-GLP 1108

Query: 990  SAGETRGAP-TPHEKALTSPSWGKGAELLLG--DQPDLIGS-----LDG--------GAK 1033
                 RG+P  P     + P    G   + G   QP  +G      L G        G K
Sbjct: 1109 GIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIK 1168

Query: 1034 SDSSSPNVGEF---ASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVG 1090
              S SP +         + +   +   +V          +K  R     GSP + P G  
Sbjct: 1169 GPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGD--PGSPGISPPGP- 1225

Query: 1091 AGEHGPKAPPPALGLGIMSNSTS-TPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPP 1147
             G+ GP  PP + G    + +T   P      G PG  G PG      P    GAP P
Sbjct: 1226 RGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPG------PDGPRGAPGP 1277



 Score = 80.1 bits (196), Expect = 1e-14
 Identities = 290/1213 (23%), Positives = 380/1213 (31%), Gaps = 198/1213 (16%)

Query: 43   GPPGPVDPAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQP--VHGFFGGQQPHHG 100
            GPPGP  P +  LG P  +G++ E      RG            P  V GF  G     G
Sbjct: 68   GPPGPQGP-IGPLGAPGPIGLSGEKGMRGDRGPPGAAGDKGDKGPTGVPGF-PGLDGIPG 125

Query: 101  HPGSHHPHQHHPHFGGNFGGPDPGASCLHGGR-LLGYGGAAGGLGSQPPFAEGYEHMAES 159
            HPG   P       G N    DPG     GGR  LG GG  G  G +         +   
Sbjct: 126  HPGPPGPRGKPGMSGHNGSRGDPG---FPGGRGALGPGGPLGHPGEKGEKGNSVFILGAV 182

Query: 160  QGPESFGPQRPGNLPDFHSS-GASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDSHSLE 218
            +G +  G +    LP    S GA   A P               + G P   G       
Sbjct: 183  KGIQ--GDRGDPGLPGLPGSWGAGGPAGPT-------------GYPGEPGLVGPPGQPGR 227

Query: 219  PRRVTNQGAVDSLEYNYPGEAPS----GHFDMFSPSDSEGQLPHYAAGRQVPGGAFPGAS 274
            P    N G     +   PGE       G   +  P D       Y   + + G   PG  
Sbjct: 228  PGLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPD----FCLYKGEKGIKG--IPGMV 281

Query: 275  AMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMP--------VG 326
             +P   G  G S + A+  +  P                F    G   +         +G
Sbjct: 282  GLPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIG 341

Query: 327  LEPSVGSR-HPLMQPPQQAPPPPQQQPPQQPP---------QQQPPPPPGLLVRQNSCPP 376
             +   G+R HP        PP P + PP  P             PP PPGLL R      
Sbjct: 342  PKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACA 401

Query: 377  AL---PRPQ--------QGEAGTPSGGLQDGGPMLPSQHAQFEYP----IHRLENRSM-- 419
             +   P PQ         GEAG P  G  D  P  P +      P    +  L   S+  
Sbjct: 402  GMIGPPGPQGFPGLPGLPGEAGIP--GRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIY 459

Query: 420  ----HPYSEPVFSMQHPPPQQAP-----NQRLQHFDAPPYMNVAKRPRFDFPGSAGVDRC 470
                +P  + +     PP  + P     N+ L   +  P             G  G    
Sbjct: 460  CSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPM------------GPPGPPGL 507

Query: 471  ASWNGSMHNGALDNHLSPSAYPGLPGEFTPP-VPDSF-PSGPPLQHPAPDHQSLQQQQQQ 528
                GS  +  L   L     PG PG   PP +P     SGPP    A     + + +  
Sbjct: 508  PGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGH 567

Query: 529  QQQQQQQQQ-----QQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHPGD 583
            + ++          Q     +     ++ +         +    +    P L   G  G 
Sbjct: 568  KGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGP-LGPPGKAGP 626

Query: 584  VGQGGLVHGGPVGGLAQPNFEREGGSTGAGRLGTFEQQAPHLAQESAWFSGPHPPPG--- 640
            VG  GL   GP G    P      G  G   L   + Q       +  + G H PPG   
Sbjct: 627  VGPPGLGFPGPPGERGHPGVPGHPGVRGPDGL---KGQKGDTISCNVTYPGRHGPPGFDG 683

Query: 641  ----DLLPRRMGGSGLPADCG----PHDPSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHV 692
                   P   G  GL    G    P  P  A  P P G    FRG + +P     +G  
Sbjct: 684  PPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPG----FRGDMGDPGFGGEKGSS 739

Query: 693  PALP-----SPGLQFGGSLGG---LGQLQSPGAG--VGLPSAASERRPPPPDFATSALGG 742
            P  P     SPG+     + G    G L  PG     G+P     R  P    A     G
Sbjct: 740  PVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGP-AG 798

Query: 743  QPGFPF--GAAGRQSTPHSG-PGVNSPPSAGGGGGSSGGGGGGG--AYPPQPDFQPSQRT 797
             PGF    G  GR+   H+G PGV  PP      G+ G  G  G   YP  P   P  + 
Sbjct: 799  IPGFLGLKGPKGREG--HAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPG-APGGKG 855

Query: 798  SASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKN----- 852
                +G         P     + G   L     A        G P +   F         
Sbjct: 856  QPGDVG---------PPGPAGMKGLPGLPGRPGAH----GPPGLPGIPGPFGDDGLPGPP 902

Query: 853  PPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSS----GSK-ASGPP 907
             P+G R L           G PG++  PG  A G PG  G SG        G+K A GPP
Sbjct: 903  GPKGPRGLP-GFPGFPGERGKPGAEGCPG--AKGEPGEKGMSGLPGDRGLRGAKGAIGPP 959

Query: 908  NPPAQGDGTSLSPNYTLESTSGNDGKPVSGG--GGRGRGRRKRDSGHVSPGTFFDKYSAA 965
                +    S           G+DG P   G  G  G   R+ + G   P  F       
Sbjct: 960  GDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGE 1019

Query: 966  PDSGGAPGVSPGQQQASGAA--VGGSSAGETRGAP-TPHEKALTSPSWGKGAELLLGDQP 1022
                G PG  PG   ++G    +G       +G P +P     +     +G +   GD  
Sbjct: 1020 KGQPGPPG-PPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPA 1078

Query: 1023 DLIGSLDGGAKSDSSSPNV-GEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGS 1081
               G    G K +  SP   G F +                    Q L      P + G 
Sbjct: 1079 SHFGP--PGPKGEPGSPGCPGHFGAS-----------------GEQGL------PGIQGP 1113

Query: 1082 PKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSS 1141
               P R    G  GP   P   G+  +          G  G  G PG PG   ++ P   
Sbjct: 1114 RGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGP--- 1170

Query: 1142 SGAPPPDEIHPLE 1154
            SG+P  + +H L+
Sbjct: 1171 SGSPGLNGLHGLK 1183



 Score = 71.6 bits (174), Expect = 5e-12
 Identities = 294/1222 (24%), Positives = 377/1222 (30%), Gaps = 278/1222 (22%)

Query: 43   GPPGPVD-PAMSAL-GEPPILGMNMEPYGFHARGHSELHAG--GLQAQP----VHGFFGG 94
            GPPGP   P +  L GE  I G      G   +  S    G  GLQ  P    ++   G 
Sbjct: 405  GPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGN 464

Query: 95   QQPHH-----GHPGSHHPHQHHPHFG------GNFGGPDP-GASCLHGGRLLGYGGAAGG 142
              P       G PG   P     + G      G  G P P G     G +  G  G  G 
Sbjct: 465  PGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSK--GDLGLPGW 522

Query: 143  LGSQ----PPFAEGYEHMAESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPN 198
            LG++    PP AEG   +    G  S  P   G   D   S    H         ++ P+
Sbjct: 523  LGTKGDPGPPGAEGPPGLPGKHGA-SGPPGNKGAKGDMVVSRVKGHKG-------ERGPD 574

Query: 199  RAASFHGLPSSSGSDSHSLEPRRVT-----------------------NQGAVDSLEYNY 235
                F G P S G D H+ E                              G V      +
Sbjct: 575  GPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGF 634

Query: 236  PGEAPS-------GHFDMFSPSDSEGQLPHYAA------GRQVPGG--AFPGASAMPRAA 280
            PG           GH  +  P   +GQ     +      GR  P G    PG    P   
Sbjct: 635  PGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQ 694

Query: 281  GMVGLSKMHAQPPQQ-QPQQQQQPQQQQQQHGVFFERFSGAR-KMPVGL-----EPSVGS 333
            G  GLS       +   P   + P     +  +    F G +   PVG       P V  
Sbjct: 695  GAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNG 754

Query: 334  RHPLMQPPQ--QAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQGEAGTPSG 391
            +  +   P      PP ++     P  + P   PG       CP A     +G AG P G
Sbjct: 755  QKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPG-------CPGA-----EGPAGIP-G 801

Query: 392  GLQDGGPMLPSQHAQFEY----PIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDA 447
             L   GP     HA F      P H  E  +     +P     +P    AP  + Q  D 
Sbjct: 802  FLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLP-GYPGSPGAPGGKGQPGDV 860

Query: 448  PPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPP-VPDSF 506
             P            PG AG+       G    GA      P   PG+PG F    +P   
Sbjct: 861  GP------------PGPAGMKGLPGLPG--RPGAH----GPPGLPGIPGPFGDDGLPG-- 900

Query: 507  PSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQ 566
            P GP      P       ++ +   +     + +  +               K M+    
Sbjct: 901  PPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGE---------------KGMSGLPG 945

Query: 567  QQRLRQPNLAQLGHPGDVGQGGLV-------HGGPVGGLAQPNFEREGGSTGA-GRLGTF 618
             + LR    A +G PGD G+  ++         GP G    P    + G+ G  GR G  
Sbjct: 946  DRGLRGAKGA-IGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGE- 1003

Query: 619  EQQAPHLAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRG 678
                           G + PPG          G P + G   P   PP PPG +G+  RG
Sbjct: 1004 --------------PGRYGPPGF-------HRGEPGEKGQPGPP-GPPGPPGSTGL--RG 1039

Query: 679  PLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATS 738
             +  P  +PG+   P  P P         G+   + P    G P  AS   PP P     
Sbjct: 1040 FIGFP-GLPGDQGEPGSPGPP-----GFSGIDGARGPKGNKGDP--ASHFGPPGPK---- 1087

Query: 739  ALGGQPGFP-----FGAAGRQSTP-----HSGPGVNSPPSAGGGGGSSGGGGGGGAY-PP 787
               G+PG P     FGA+G Q  P        PG   PP + G  G  G  G  G    P
Sbjct: 1088 ---GEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQP 1144

Query: 788  QPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALS-TACQNMIASLGAPNLNV 846
                 P  R      G         PS    L G   L     T   + +  +G P    
Sbjct: 1145 GEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPG--- 1201

Query: 847  TFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGP 906
                   P  K +     + G +  G  G    PG   PG+ GP GP+G +    K    
Sbjct: 1202 ---PVGIPGLKGERGDPGSPGISPPGPRGKKGPPG--PPGSSGPPGPAGATGRAPKDIPD 1256

Query: 907  PNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAP 966
            P PP  GD     P    +   G  G P   G          D G   P          P
Sbjct: 1257 PGPP--GDQGPPGP----DGPRGAPGPPGLPGSVDLLRGEPGDCGLPGP-------PGPP 1303

Query: 967  DSGGAPGVS--PGQQQASG--AAVGGSSAGETRGAP-TPHEKALTSPSWGKGAELLLGDQ 1021
               G PG    PG     G    VG        G P  P EK L  P   KG   L    
Sbjct: 1304 GPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGRKGPTGL---- 1359

Query: 1022 PDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGS 1081
                     G + +   P              A+ D+               R P + G+
Sbjct: 1360 --------PGPRGEPGPP--------------ADVDD-------------CPRIPGLPGA 1384

Query: 1082 PKL--PPRGVG-AGEHGPKAP----PPAL----GLGIMSNSTSTPDSYGGGGGPGHPGTP 1130
            P +  P   +G  G  GP  P     P L    G+  +  S   P   G  G  G+PG P
Sbjct: 1385 PGMRGPEGAMGLPGMRGPSGPGCKGEPGLDGRRGVDGVPGSPGPPGRKGDTGEDGYPGGP 1444

Query: 1131 GLEQVRTPTSSSGAPPPDEIHP 1152
            G      P    G P P    P
Sbjct: 1445 G------PPGPIGDPGPKGFGP 1460



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 127/516 (24%), Positives = 157/516 (30%), Gaps = 160/516 (31%)

Query: 656  CGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSP 715
            C P   S  PP PPG  G +  GPL  P                    G +G  G+    
Sbjct: 57   CVPEKGSRGPPGPPGPQGPI--GPLGAP--------------------GPIGLSGEKGMR 94

Query: 716  GAGVGLPSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPPSAGGGGGS 775
            G   G P AA ++    P        G PGFP G  G        PG   PP   G  G 
Sbjct: 95   G-DRGPPGAAGDKGDKGPT-------GVPGFP-GLDGI-------PGHPGPPGPRGKPGM 138

Query: 776  SGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGS-FNKPSSKDNLFGQSCLAALSTACQN 834
            SG  G  G     P F P  R      GAL  G     P  K                 N
Sbjct: 139  SGHNGSRG----DPGF-PGGR------GALGPGGPLGHPGEKGEK-------------GN 174

Query: 835  MIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPS 894
             +  LGA                            + G+ G    PG   PG+ G GGP+
Sbjct: 175  SVFILGAVK-------------------------GIQGDRGDPGLPG--LPGSWGAGGPA 207

Query: 895  GTSSSGSKAS--GPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGH 952
            G +    +    GPP  P +  G   +P   ++   G+ G+ V   G  G       +  
Sbjct: 208  GPTGYPGEPGLVGPPGQPGR-PGLKGNPGVGVKGQMGDPGE-VGQQGSPG------PTLL 259

Query: 953  VSPGTFFDKYSAAPDSGGAPGV-----SPGQQQASGAAVGGSSAGETRGAPTPHEKALTS 1007
            V P  F   Y       G PG+      PG++  SG    G         P     +  S
Sbjct: 260  VEPPDFC-LYKGEKGIKGIPGMVGLPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGS 318

Query: 1008 PSW-GKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNP 1066
            P + G   EL L   P L G +  G K D                        +     P
Sbjct: 319  PGFPGLKGELGLVGDPGLFGLI--GPKGDPG----------------------NRGHPGP 354

Query: 1067 QALVKASRSPL--VTGSPKLPPRGVGAGEHGPKAPPPALG-------------------- 1104
              ++     PL    G P  P R    G+ GP  PP  LG                    
Sbjct: 355  PGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIGPPGPQGFPG 414

Query: 1105 -------LGIMSNSTSTPDSYGGGGGPGHPGTPGLE 1133
                    GI     S P   G  G PG PG PGL+
Sbjct: 415  LPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQ 450



 Score = 33.9 bits (76), Expect = 1.1
 Identities = 29/111 (26%), Positives = 43/111 (38%), Gaps = 12/111 (10%)

Query: 1092 GEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPPDEIH 1151
            G+ G    P + G G  +  T  P   G  G PG PG PGL+             P E+ 
Sbjct: 190  GDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKGNPGVGVKGQMGDPGEVG 249

Query: 1152 PLEILQAQIQLQRQQFSISEDQPLGLKG-----------GKKGECAVGASG 1191
                    + ++   F + + +  G+KG           G+KGE  +GA G
Sbjct: 250  QQGSPGPTLLVEPPDFCLYKGEK-GIKGIPGMVGLPGPPGRKGESGIGAKG 299


>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2
           [Homo sapiens]
          Length = 2191

 Score = 93.2 bits (230), Expect = 1e-18
 Identities = 130/486 (26%), Positives = 165/486 (33%), Gaps = 84/486 (17%)

Query: 514 HPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQP 573
           H    H +LQQQ  Q QQQQQQQQQQQQQQQQQQ     N +L                 
Sbjct: 40  HHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSL----------------- 82

Query: 574 NLAQLGHPGDVGQGGLVHGGPVGGLAQPNFERE----GGSTGAGRLGTFEQQAPHLAQES 629
                             GG  GG  QP  + E    GG+  +   G  +   P L  + 
Sbjct: 83  ------------------GGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKP 124

Query: 630 AWFSGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPGE 689
                  P  G+    R    GL A  G   P   P   PGG G    GP   P      
Sbjct: 125 GDEDDAPPKMGEPAGGRYEHPGLGA-LGTQQP---PVAVPGGGG----GPAAVPEFNNYY 176

Query: 690 GH-VPALPSPGLQFGGSLGGLGQLQSPGAG-VGLPSAASERRPPPPDFATSALGGQPGFP 747
           G   PA   PG + G      G  QSPG G +   SAA+   P   D   ++  G P   
Sbjct: 177 GSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQ 236

Query: 748 FGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSL 807
                  S P +G G       GGGGGS GGGGGGGA             +A+   A   
Sbjct: 237 CNHYPGYSRPGAGGGGGG--GGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGG 294

Query: 808 GSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDG 867
           G           +G                 L +P          P  G          G
Sbjct: 295 GGGGGYGGSSAGYG----------------VLSSPRQQGGGMMMGPGGGGAASLSKAAAG 338

Query: 868 AAVAG---NPGSDYFPGGTAP------GAPGPGGPS--GTSSSGSKASGPPNPPAQGDGT 916
           +A  G     G +  P G  P       +P P   S  G+    S  S PP PP+Q    
Sbjct: 339 SAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQ 398

Query: 917 SLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSP 976
           + +      + +   G+  + G G G+    + +          + S    S G PG + 
Sbjct: 399 AAA------AGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTM 452

Query: 977 GQQQAS 982
           G+ Q S
Sbjct: 453 GRSQGS 458



 Score = 81.6 bits (200), Expect = 4e-15
 Identities = 230/994 (23%), Positives = 308/994 (30%), Gaps = 251/994 (25%)

Query: 44  PPGPVDPAMSALGE----PPILGMNMEPYGFHARGHSELHAGGLQAQPV----------- 88
           PPGP  P +S  G+    PP +G   EP G     H  L A G Q  PV           
Sbjct: 115 PPGP--PLLSKPGDEDDAPPKMG---EPAGGRYE-HPGLGALGTQQPPVAVPGGGGGPAA 168

Query: 89  ----HGFFGGQQPHHGHPGSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLG 144
               + ++G   P  G PG     +  P F  + G   PG   +H         AAG  G
Sbjct: 169 VPEFNNYYGSAAPASGGPGG----RAGPCFDQHGGQQSPGMGMMHSAS----AAAAGAPG 220

Query: 145 SQPPFAEGYEHMAESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFH 204
           S  P    +E    SQ     G  RPG        G                 +      
Sbjct: 221 SMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGG------------SGGGGGG 268

Query: 205 GLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAAGRQ 264
           G   + G+ + ++         A         G + +G+  + SP             RQ
Sbjct: 269 GGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSP-------------RQ 315

Query: 265 VPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMP 324
             GG   G    P   G   LSK  A                       F+RF+G  + P
Sbjct: 316 QGGGMMMG----PGGGGAASLSKAAAGSAAGG-----------------FQRFAGQNQHP 354

Query: 325 VGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQG 384
            G  P++     L+  P    P  +      P    P  PP         PP+ P+ Q  
Sbjct: 355 SGATPTLNQ---LLTSPS---PMMRSYGGSYPEYSSPSAPPP--------PPSQPQSQAA 400

Query: 385 EAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQH 444
            AG  +GG Q    M   +    +Y        +    S P  S   P P    +Q    
Sbjct: 401 AAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQ---- 456

Query: 445 FDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSP---SAYPGLPGEFTPP 501
             +P    V KRP+    GS                  + H  P   S YPG  G + PP
Sbjct: 457 -GSPMDPMVMKRPQLYGMGS------------------NPHSQPQQSSPYPG--GSYGPP 495

Query: 502 VPDSFPSGPPLQHPA-------PDHQS-------------------------LQQQQQQQ 529
            P  +P G   + P        P  Q                           QQ QQ  
Sbjct: 496 GPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVSGYCQQGQQPY 555

Query: 530 QQQQQQ-------------QQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLA 576
             QQ Q             Q QQ+ Q QQ   Q+             +   + L   NL 
Sbjct: 556 YSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDL---NLI 612

Query: 577 QLGHPGDVGQ-GGLVHGGPVGGLAQ-PNFEREGGSTGAGRLGTFEQQAPHLAQESAWFS- 633
           Q   P  +    G +   P G  A   +     GST +    +   Q+P     S   S 
Sbjct: 613 QQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSS 672

Query: 634 ---GPHPPP-GDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGSG------VLFRGPL-QE 682
              GP P P G  +      SG P        S  PP PPG          L + P+ QE
Sbjct: 673 IPGGPSPSPVGSPVGSNQSRSG-PISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQE 731

Query: 683 PMRMPGEGHVPAL---------------PSPGLQFGGSL-------------------GG 708
              M G    P +               PSPG Q    +                   G 
Sbjct: 732 RGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGP 791

Query: 709 LGQLQSPGAGVGLPSAASERRPPPPDFATSA---LGGQ-PGFPFGA--------AGRQST 756
            G    P A  G+PSA+     P P    SA   + GQ P  P GA        AG Q+ 
Sbjct: 792 QGNYSRPPAYSGVPSASYS--GPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNR 849

Query: 757 PHSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDF-QPSQRTSASKLGALSLGSFNKPSS 815
           P  G   +  PS+ G     G G G    PP P   + +Q  +A+ + A +  + ++  S
Sbjct: 850 PFPGNMSSMTPSSPGMSQQGGPGMG----PPMPTVNRKAQEAAAAVMQAAANSAQSRQGS 905

Query: 816 KDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETD---GAAVAG 872
              +     +A+ S   Q M       N +   N + PP        N +    G A   
Sbjct: 906 FPGMNQSGLMASSSPYSQPM------NNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMM 959

Query: 873 NPGSDYFP-----GGTAPGAPGPGGPSGTSSSGS 901
           +PG    P      G   G P P   S  SSS +
Sbjct: 960 SPGESKLPLPLKADGKEEGTPQPESKSKKSSSST 993



 Score = 78.6 bits (192), Expect = 4e-14
 Identities = 174/807 (21%), Positives = 261/807 (32%), Gaps = 123/807 (15%)

Query: 31  NTHFKAPAFHTGGPPGPVDPAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHG 90
           N ++ + A  +GGP G   P     G     GM M            +H+    A    G
Sbjct: 173 NNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGM------------MHSASAAAAGAPG 220

Query: 91  FFGG-QQPHHGHPGS---HHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAG-GLGS 145
                Q  H G+P S   H+P    P  GG  GG   G     GG   G  GA G G G+
Sbjct: 221 SMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGA 280

Query: 146 QPPFAEGYEHMAESQGPESFGPQRPG----NLPDFHSSGASSHAVPAPCLPLDQSPNRAA 201
               A      A   G   +G    G    + P     G            L ++   +A
Sbjct: 281 VAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSA 340

Query: 202 SFHGLPSSSGSDSHSLEPRRVTNQ--GAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHY 259
           +  G    +G + H        NQ   +   +  +Y G  P  +    +P     Q    
Sbjct: 341 A-GGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPE-YSSPSAPPPPPSQPQSQ 398

Query: 260 AAGRQVPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSG 319
           AA      G    A+ M     M G     A P     QQ+  P       G    R  G
Sbjct: 399 AAAAGAAAGGQQAAAGMGLGKDM-GAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQG 457

Query: 320 ARKMPVGLEP----SVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCP 375
           +   P+ ++      +GS +P  QP Q +P P     P  P +     P G+  R     
Sbjct: 458 SPMDPMVMKRPQLYGMGS-NPHSQPQQSSPYPGGSYGPPGPQRY----PIGIQGRTPGAM 512

Query: 376 PALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPP- 434
             +  PQQ ++G  +   ++   ++P Q+ Q    +     +   PY        H PP 
Sbjct: 513 AGMQYPQQQDSGDAT--WKETFWLMPPQYGQ--QGVSGYCQQGQQPYYSQQPQPPHLPPQ 568

Query: 435 -QQAPNQRLQHF--------------DAPPY---------MNVAKRPR-----------F 459
            Q  P+Q  Q +                PP          +N+ ++ R            
Sbjct: 569 AQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSID 628

Query: 460 DFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSFPSGP---PLQHPA 516
           D P        ++ + S    +  +  +P+  P  P     P   S P GP   P+  P 
Sbjct: 629 DLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSP--HASPHLSSIPGGPSPSPVGSPV 686

Query: 517 PDHQ---------SLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQ 567
             +Q         S+   Q   Q    Q +        Q    ++   +   Q   +  Q
Sbjct: 687 GSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQ 746

Query: 568 QRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGG--STGAGRLGTFEQQAPHL 625
              +Q   +   HP     GG +H G +    Q N     G   +  G  G + +   + 
Sbjct: 747 YGPQQTGPSMSPHP---SPGGQMHAG-ISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYS 802

Query: 626 AQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMR 685
              SA +SGP P  G     +M G G              P  P G+  L R P      
Sbjct: 803 GVPSASYSGPGPGMGISANNQMHGQG--------------PSQPCGAVPLGRMPSAGMQN 848

Query: 686 MPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPS-------AASERRPPPPDFATS 738
            P  G++ ++         S  G+ Q   PG G  +P+       AA+       + A S
Sbjct: 849 RPFPGNMSSMTP-------SSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQS 901

Query: 739 ALGGQPGFPFGAAGRQSTPHSGPGVNS 765
             G  PG         S+P+S P  NS
Sbjct: 902 RQGSFPGMNQSGLMASSSPYSQPMNNS 928



 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 119/475 (25%), Positives = 168/475 (35%), Gaps = 65/475 (13%)

Query: 703  GGSLGGLGQ----LQSPGAGVGLPSAASERRPPPPDFATSALGGQPGFP----FGAAGRQ 754
            GG+ GG  Q    ++ P  G    SAA  +  PP     S  G +   P      A GR 
Sbjct: 83   GGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRY 142

Query: 755  STPHSGP-GVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKP 813
              P  G  G   PP A       GGGGG  A P   ++  S   ++   G  +   F++ 
Sbjct: 143  EHPGLGALGTQQPPVA-----VPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQH 197

Query: 814  SSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGN 873
              + +  G   + + S A      + GAP             G     QN  +G     N
Sbjct: 198  GGQQSP-GMGMMHSASAA------AAGAP-------------GSMDPLQNSHEGYP---N 234

Query: 874  PGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGK 933
               +++PG + PGA G GG  G    GS   G       G G   +    + + +     
Sbjct: 235  SQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGG----GAGAGGAGAGAVAAAAAAAAA 290

Query: 934  PVSGGGGRGRGRRKRDSGHVS-PGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSS-- 990
               GGGG G G      G +S P          P  GGA  +S   + A+G+A GG    
Sbjct: 291  AAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLS---KAAAGSAAGGFQRF 347

Query: 991  AGETR---GAPTPHEKALTSPS---WGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEF 1044
            AG+ +   GA     + LTSPS      G        P          +S +++      
Sbjct: 348  AGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAG 407

Query: 1045 ASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAP----- 1099
                 +     +D  +  +    A   A +      SP  P   +G  +  P  P     
Sbjct: 408  GQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKR 467

Query: 1100 PPALGLGIMSNSTSTPDS---YGGG--GGPGHPGTPGLEQVRTPTSSSGAPPPDE 1149
            P   G+G  SN  S P     Y GG  G PG    P   Q RTP + +G   P +
Sbjct: 468  PQLYGMG--SNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQ 520



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 109/462 (23%), Positives = 164/462 (35%), Gaps = 81/462 (17%)

Query: 95   QQPHHGHPGSHHPHQHHPHFGGNFGGPDPG-------ASCLHGGRLLGYGGAAGGLGSQP 147
            Q P   + GS    Q     G N     PG       AS  HG      GG +  +    
Sbjct: 1121 QPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHD 1180

Query: 148  PFAEGYEHMAESQGPE--SFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHG 205
            PF++    +++S  P+  S  P  P      +  G S   +P     +   PN+   F G
Sbjct: 1181 PFSD----VSDSSFPKRNSMTPNAP------YQQGMS---MPDVMGRMPYEPNKDP-FGG 1226

Query: 206  LPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAA---- 261
            +    GS    +   ++ N    D   YN   ++PSG          + Q P+ A+    
Sbjct: 1227 MRKVPGSSEPFMTQGQMPNSSMQDM--YN---QSPSGAMSNLGMGQRQ-QFPYGASYDRR 1280

Query: 262  ----GRQVPGGAFPGASAMPRAAGMVGLS------KMHAQ----PPQQQPQ----QQQQP 303
                G+Q PG   P +   P      GL       K H      PP ++ +      Q  
Sbjct: 1281 HEPYGQQYPGQG-PPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYS 1339

Query: 304  QQQQQQHGVFFERFSGARKMPV-GLEPSVGSRHPLMQPPQ---QAPPPPQQQPPQQPPQQ 359
             QQQ+ +  +   +SG  + P+ G  P   SR  +  P Q      PP     P Q    
Sbjct: 1340 SQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSS 1399

Query: 360  QPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFEY--PIHRLENR 417
            + P       R +     +P P Q   G P G  Q   P  P  +   +   P  R+ + 
Sbjct: 1400 EGPQQNMWAARND-----MPYPYQNRQG-PGGPTQ--APPYPGMNRTDDMMVPDQRINHE 1451

Query: 418  SMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSM 477
            S  P       +    P  + +  +Q    PP      +P +  P S       + + + 
Sbjct: 1452 SQWPSH-----VSQRQPYMSSSASMQPITRPP------QPSYQTPPSLPNHISRAPSPAS 1500

Query: 478  HNGALDNHLSPSAYPGLPG----EFTPPVPDSFPSGPPLQHP 515
               +L+N +SPS  P LP     +  P VP S  +GPP Q P
Sbjct: 1501 FQRSLENRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQPP 1542



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 207/923 (22%), Positives = 264/923 (28%), Gaps = 200/923 (21%)

Query: 335  HPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQ 394
            H L Q   Q     QQQ  QQ  QQQ   P   +   NS             G   GG  
Sbjct: 46   HALQQQLNQFQQQQQQQQQQQQQQQQQQHP---ISNNNSL------------GGAGGGAP 90

Query: 395  DGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVA 454
              GP         E P H     S             PP     ++     DAPP M   
Sbjct: 91   QPGP-------DMEQPQHGGAKDSA------AGGQADPPGPPLLSKPGDEDDAPPKMGEP 137

Query: 455  KRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPG--EFTPPVPDSFPSGPPL 512
               R++ PG                GAL     P A PG  G     P   + + S  P 
Sbjct: 138  AGGRYEHPGL---------------GALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPA 182

Query: 513  QHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQ 572
                P  ++     Q   QQ                       L        N Q     
Sbjct: 183  SG-GPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCN-HY 240

Query: 573  PNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGAGRLGTFEQQAPHLAQESA-- 630
            P  ++ G  G  G GG   GG  GG         GG  GAG  G     A   A  +A  
Sbjct: 241  PGYSRPGAGGGGGGGGGGGGGSGGGGG-------GGGAGAGGAGAGAVAAAAAAAAAAAG 293

Query: 631  -----WFSGPHPPPGDLLPRRMGGSGL---PADCGPHDPSLAPPPPPGGSGVLFRGPLQE 682
                  + G     G L   R  G G+   P   G    S A      G    F G  Q 
Sbjct: 294  GGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQH 353

Query: 683  PM-RMPGEGHVPALPSPGLQ-FGGSL-----------------------GGLGQLQSPGA 717
            P    P    +   PSP ++ +GGS                        G     Q   A
Sbjct: 354  PSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAA 413

Query: 718  GVGLPS-------------AASERRPPP---PDFATSALGGQPGFPFGAA--------GR 753
            G+GL               AA+++R  P   P      +G   G P            G 
Sbjct: 414  GMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGM 473

Query: 754  QSTPHSGPGVNSPPSAGGGG------------GSSGGGGGGGAYPPQPD----------- 790
             S PHS P  +SP   G  G            G + G   G  YP Q D           
Sbjct: 474  GSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFW 533

Query: 791  FQPSQRTSASKLGALSLGS---FNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVT 847
              P Q       G    G    +++     +L  Q+    L +  Q         +    
Sbjct: 534  LMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQA--QYLPSQSQQRYQPQQDMSQEGY 591

Query: 848  FNKKNPPEGKRK-------LSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSG 900
              +  PP    K       L Q E   +    +   D  P GT          SG++SS 
Sbjct: 592  GTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQ 651

Query: 901  SKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFD 960
               S P   P        SP+ +    S   G P     G   G  +  SG +SP     
Sbjct: 652  GDQSNPAQSP-------FSPHAS-PHLSSIPGGPSPSPVGSPVGSNQSRSGPISP----- 698

Query: 961  KYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGD 1020
               A+      P   PG Q  S      SS      +P P E+   + +         G 
Sbjct: 699  ---ASIPGSQMPPQPPGSQSES------SSHPALSQSPMPQERGFMAGTQRNPQMAQYGP 749

Query: 1021 QPDLIGSLDGGAKSDSSSPN------VGEFASDEVSTSYANEDEVSSSSDNPQALVKASR 1074
            Q        G + S   SP       +  F     S +Y  +     S   PQ     SR
Sbjct: 750  QQT------GPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQ----MSQYGPQG--NYSR 797

Query: 1075 SPLVTGSPKLPPRGVGAGE----------HGPKAPPPALGLGIMSNSTSTPDSYGGGGGP 1124
             P  +G P     G G G            GP  P  A+ LG M ++      + G    
Sbjct: 798  PPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSS 857

Query: 1125 GHPGTPGLEQVRTPTSSSGAPPP 1147
              P +PG+ Q   P    G P P
Sbjct: 858  MTPSSPGMSQQGGP--GMGPPMP 878



 Score = 45.1 bits (105), Expect = 5e-04
 Identities = 161/785 (20%), Positives = 251/785 (31%), Gaps = 195/785 (24%)

Query: 142  GLGSQPPFAEGYEHMAESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRA- 200
            G  SQPP A G  +  +    +    +RP +LPD   S             +D  P    
Sbjct: 592  GTRSQPPLAPGKPNHEDLNLIQQ---ERPSSLPDLSGS-------------IDDLPTGTE 635

Query: 201  ASFHGLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYA 260
            A+     S+SGS S         +QG     + + P ++P      FSP  S    PH +
Sbjct: 636  ATLSSAVSASGSTS---------SQG-----DQSNPAQSP------FSPHAS----PHLS 671

Query: 261  AGRQVPGGAFPGASAMPRAAGMVGLSKMHAQP--PQQQPQQQQQPQQQQQQHGVFFERFS 318
            +   +PGG  P     P     VG ++  + P  P   P  Q  PQ    Q        S
Sbjct: 672  S---IPGGPSPSPVGSP-----VGSNQSRSGPISPASIPGSQMPPQPPGSQ--------S 715

Query: 319  GARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPP------GLLVRQN 372
             +   P   +  +      M   Q+ P   Q  P Q  P   P P P      G+   Q 
Sbjct: 716  ESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQ 775

Query: 373  SCPPALPRPQQGE-------------AGTPSGGLQDGGPML------------PSQHAQF 407
            S       PQ  +             +G PS      GP +            PSQ    
Sbjct: 776  SNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGA 835

Query: 408  ----EYPIHRLENR-------SMHPYSEPVFSMQHP---PPQQAPNQRLQHFDAPPYM-- 451
                  P   ++NR       SM P S  +     P   PP    N++ Q   A      
Sbjct: 836  VPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAA 895

Query: 452  -NVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSFPSGP 510
             N A+  +  FPG       AS   S ++  ++N  S       P    P + +S  +  
Sbjct: 896  ANSAQSRQGSFPGMNQSGLMAS--SSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASV 953

Query: 511  PLQHP-APDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQR 569
             L    +P    L    +   +++   Q + + ++             + ++ +  +++ 
Sbjct: 954  GLADMMSPGESKLPLPLKADGKEEGTPQPESKSKKSSSSTTTGEKITKVYELGNEPERKL 1013

Query: 570  LRQPNLAQLGHPGD-------VGQGGL------VHGGPVGGLAQPNFEREGGSTGAG-RL 615
                 L  +   G        VG+  L      V    +GGLAQ N  ++         +
Sbjct: 1014 WVDRYLTFMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNV 1073

Query: 616  GTFEQQAPHLAQESAWF---------SGPHPPP--------------------------G 640
            GT    A  L ++   +          G  PPP                          G
Sbjct: 1074 GTSSSAASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQG 1133

Query: 641  DLLPRRMGGSGL---PADCGPHDPSLAP----PPPPGG---------------------- 671
               P+  G + +   P D  P  P+  P     P  GG                      
Sbjct: 1134 PQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKR 1193

Query: 672  SGVLFRGPLQEPMRMPGE-GHVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASE--- 727
            + +    P Q+ M MP   G +P  P+    FGG     G  +       +P+++ +   
Sbjct: 1194 NSMTPNAPYQQGMSMPDVMGRMPYEPNKD-PFGGMRKVPGSSEPFMTQGQMPNSSMQDMY 1252

Query: 728  RRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGGGGAYPP 787
             + P    +   +G +  FP+GA+      H   G   P      G    GG   G YP 
Sbjct: 1253 NQSPSGAMSNLGMGQRQQFPYGAS--YDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQ 1310

Query: 788  QPDFQ 792
            QP+++
Sbjct: 1311 QPNYK 1315



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 33/102 (32%), Positives = 40/102 (39%), Gaps = 14/102 (13%)

Query: 294 QQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQPP 353
           QQQ QQQQQ QQQQQQH +      G            G   P   P  + P     +  
Sbjct: 58  QQQQQQQQQQQQQQQQHPISNNNSLG----------GAGGGAPQPGPDMEQPQHGGAKDS 107

Query: 354 QQPPQQQPPPPPGLLVR---QNSCPPALPRPQQGEAGTPSGG 392
               Q  PP PP LL +   ++  PP +  P  G    P  G
Sbjct: 108 AAGGQADPPGPP-LLSKPGDEDDAPPKMGEPAGGRYEHPGLG 148



 Score = 33.1 bits (74), Expect = 1.8
 Identities = 81/347 (23%), Positives = 117/347 (33%), Gaps = 83/347 (23%)

Query: 51   AMSALGEPPILGMNME-PYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHGHPGSHHPHQ 109
            AMS LG    +G   + PYG     +   H    Q  P  G   GQ P+ GH    +P Q
Sbjct: 1259 AMSNLG----MGQRQQFPYG---ASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQ 1311

Query: 110  --HHPHFGGNFGGPDPGASCLHGGRLLG-------------YGGAAGGLGSQPPFAEGYE 154
              +  H  G +G P    +  H G +               YGG+  G   +P       
Sbjct: 1312 PNYKRHMDGMYGPP----AKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRP------- 1360

Query: 155  HMAESQGPESFGPQR---PGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSG 211
               + Q P  +  +R   PG +         +H +P   +     P +++S  G   +  
Sbjct: 1361 --IQGQYPYPYSRERMQGPGQI--------QTHGIPPQMM---GGPLQSSSSEGPQQNMW 1407

Query: 212  SDSHSLEPRRVTNQGAVDSLEY-NYPGEAPSGHFDMFSPS---DSEGQLPHYAAGRQVPG 267
            +  + +       QG     +   YPG   +   DM  P    + E Q P + + RQ   
Sbjct: 1408 AARNDMPYPYQNRQGPGGPTQAPPYPGMNRTD--DMMVPDQRINHESQWPSHVSQRQ--- 1462

Query: 268  GAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQH-GVFFERFSGARKMPVG 326
                    M  +A M        QP  + PQ   Q       H        S  R +   
Sbjct: 1463 ------PYMSSSASM--------QPITRPPQPSYQTPPSLPNHISRAPSPASFQRSLENR 1508

Query: 327  LEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPP-------PPG 366
            + PS     P M+  +  P  P  Q    PP  QPPP       PPG
Sbjct: 1509 MSPSKSPFLPSMKMQKVMPTVPTSQVTGPPP--QPPPIRREITFPPG 1553



 Score = 30.8 bits (68), Expect = 9.0
 Identities = 76/358 (21%), Positives = 108/358 (30%), Gaps = 47/358 (13%)

Query: 43  GPPGPVDPAMSALGEPPILGMN----MEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPH 98
           G    +  A+SA G     G        P+  HA  H     GG    PV    G  Q  
Sbjct: 633 GTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSR 692

Query: 99  HG---------------HPGSHHPHQHHPHFGGNFGGPDPG--ASCLHGGRLLGYGGAAG 141
            G                PGS      HP    +    + G  A      ++  YG    
Sbjct: 693 SGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQT 752

Query: 142 GLGSQP-PFAEGYEH-----MAESQGPESFGPQR-----PGNL---PDFHSSGASSHAVP 187
           G    P P   G  H       +S    ++GPQ       GN    P +    ++S++ P
Sbjct: 753 GPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGP 812

Query: 188 APCLPLDQSPNRAASFHGLPSSSGSDSHSLEPRRVTNQ----GAVDSLEYNYPGEAPSGH 243
            P + +  S N      G     G+      P          G + S+  + PG +  G 
Sbjct: 813 GPGMGI--SANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGG 870

Query: 244 FDMFSPSDSEGQLPHYAAGRQVPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQP 303
             M  P  +  +    AA   +   A    S      GM     M +  P  QP      
Sbjct: 871 PGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSS 930

Query: 304 QQQQQQHGVFFERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQP 361
               Q        +S A  M      SVG    +M P +   P P +   ++    QP
Sbjct: 931 LMNTQA-----PPYSMAPAMVNSSAASVGLA-DMMSPGESKLPLPLKADGKEEGTPQP 982


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 91.7 bits (226), Expect = 4e-18
 Identities = 224/871 (25%), Positives = 290/871 (33%), Gaps = 198/871 (22%)

Query: 156  MAESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDSH 215
            MAE +  +    Q+       HS+  +     +P L L + P +    HGL    G    
Sbjct: 3592 MAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRL-LTKLPGQLLPGHGLQPPQGPPGG 3650

Query: 216  SLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAAGRQV--PGGAFPGA 273
                 R+T  G         PG+ P G F   + +  + Q     AG      GG FPG 
Sbjct: 3651 QAGGLRLTPGGMA------LPGQ-PGGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGN 3703

Query: 274  SAMPRAAGMVG--LSKMHAQPPQQQPQ-----QQQQPQQQQQQHGVFFERFSGARKMPVG 326
             A+ R+ G     L +   Q  QQ+ Q     QQQQ QQQQQQH +              
Sbjct: 3704 LAL-RSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLL-------------- 3748

Query: 327  LEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPP--GLLVRQNSC-PPALPRPQQ 383
                   +  + Q  QQ P     Q     PQ   PP    GLLV+Q S  PP  P+   
Sbjct: 3749 ------GQVAIQQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGML 3802

Query: 384  GEAGTPSGGLQDGGPMLPS-QHAQFEYPIHR-LENRSMHPYSEPVFSMQHPPPQQAPNQR 441
            G A       Q  G + P   H Q      R L +  +    + +   +    QQ   Q+
Sbjct: 3803 GPAQVAVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQ 3862

Query: 442  LQHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPP 501
             QH                        +  S  G  H     + +S S  P L  +    
Sbjct: 3863 -QH-----------------------QQQGSMAGLSH--LQQSLMSHSGQPKLSAQ---- 3892

Query: 502  VPDSFPSGPPLQHPAPDHQSLQQQQQQQ-------QQQQQQQQQQQQQQQQQQQQQRQNA 554
             P         Q      Q LQQQQQQQ       QQQQ QQQQQQQQ QQQQQQQ Q  
Sbjct: 3893 -PMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQ 3951

Query: 555  ALMIKQMASRNQQQRLRQPNLAQLG----------------------------------H 580
               ++Q   + QQQ  +Q    Q+G                                   
Sbjct: 3952 QQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSS 4011

Query: 581  PGDVGQGGLVHGGPVGGL--AQPNFEREGGSTGAG---RLGTF-EQQAPHLAQESAWFSG 634
            PG +G   L+ G     +  A  +   EG ST  G    +GT  E  A    +     SG
Sbjct: 4012 PGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSG 4071

Query: 635  ----------PHPPPGDLL---PRRMGG-----------------------SGLPADCGP 658
                      P P P  L    P R+ G                       S   A   P
Sbjct: 4072 DSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVP 4131

Query: 659  H---DPSLAPPPPPGGSGVLFRGPLQEPMRMP---GEGHVPALPSPGLQFGGSLGG---- 708
            H    PS++    PG       GP Q  +  P     G  P  P P LQ G  L G    
Sbjct: 4132 HLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIM 4191

Query: 709  --LGQLQSPGAGVGLPSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSP 766
              +GQL++   GV   +       P       AL  Q       A RQ+ P+  PG  + 
Sbjct: 4192 PTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTS 4251

Query: 767  PSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLA 826
            P  G  G     GG      P P   P Q           LG+  +P     L   +   
Sbjct: 4252 PLQGLLGCQPQLGGF-----PGPQTGPLQ----------ELGAGPRPQGPPRL--PAPPG 4294

Query: 827  ALSTACQNMIASLG----APNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGG 882
            ALST        LG     P  +     K P +     SQ  T+      +PG+    G 
Sbjct: 4295 ALSTG-----PVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGP 4349

Query: 883  TAPGAPGPGGPSGTSSSG---SKASGPPNPP 910
            T    PG   P+    +    SK  GP +PP
Sbjct: 4350 TLEPPPGRVSPAAAQLADTLFSKGLGPWDPP 4380



 Score = 75.9 bits (185), Expect = 2e-13
 Identities = 190/771 (24%), Positives = 247/771 (32%), Gaps = 195/771 (25%)

Query: 286  SKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRHPLMQPPQQAP 345
            + + A+   +Q QQQQQ QQQQQQH              + L PS   R  L + P Q  
Sbjct: 3589 TNLMAEYRNKQQQQQQQQQQQQQQHSAV-----------LALSPSQSPRL-LTKLPGQLL 3636

Query: 346  PPPQQQPPQQPPQQQPP----PPPGLLVRQNSCPP----ALPRPQQ----GEAGT---PS 390
            P    QPPQ PP  Q       P G+ +      P    AL + QQ    G AG+   PS
Sbjct: 3637 PGHGLQPPQGPPGGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAGPS 3696

Query: 391  GGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPY 450
            GG   G   L S           L+ R +    + +   Q    QQ   Q+ QH      
Sbjct: 3697 GGFFPGNLALRSLGPDSRL----LQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVA 3752

Query: 451  MNVAKR--PRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPV------ 502
            +   ++  P      + G         S H G L   LSP    G  G   P        
Sbjct: 3753 IQQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQ 3812

Query: 503  --PDSF-PSGPPLQ------------------HPAPDHQSLQQQQQQQQQQQQQQ----- 536
              P +  P GP  Q                       H+ +  QQQQQQQQ QQQ     
Sbjct: 3813 QHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAG 3872

Query: 537  ----------------------------------QQQQQQQQQQQQQQRQNAALMIKQMA 562
                                              QQQQQ QQQQQQQ +Q   L  +Q+ 
Sbjct: 3873 LSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQ 3932

Query: 563  SRNQQQRLRQPNLAQLGH------------------------------------PGDVGQ 586
             + QQQ+L+Q    QL                                      P    Q
Sbjct: 3933 QQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQ 3992

Query: 587  GGLVHGGPVGGLAQPNFEREGGSTGAGRLGTFEQQAPHLAQESAWFSGPHPPPGDLLPRR 646
              +  G  +      +F   G       L   EQ     A  S    GP    G  L   
Sbjct: 3993 QQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIG 4052

Query: 647  MGGSGLPADCGPHDPSLA---------PPPPPGGSGVLFRGPLQEPMRMPG--EGHVPAL 695
                 +  + G   PSL+         P P P  S +     LQ P+R+PG  +  V  L
Sbjct: 4053 TTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSL----QLQPPLRLPGQQQQQVSLL 4108

Query: 696  PSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALGGQPG-FPFGAAGRQ 754
             + G   GGS G LG   S  A   +P   ++         + +LG QPG       G Q
Sbjct: 4109 HTAG---GGSHGQLGSGSSSEAS-SVPHLLAQ--------PSVSLGDQPGSMTQNLLGPQ 4156

Query: 755  STPHSGPGVNS----PPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSF 810
                  P  N+    PP  G    S  G  G G  P           +  +L A   G  
Sbjct: 4157 QPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMP-----------TVGQLRAQLQGVL 4205

Query: 811  NKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAV 870
             K     +L  Q      +   Q  +    A        ++ PP       +  T  + +
Sbjct: 4206 AKNPQLRHLSPQQQQQLQALLMQRQLQQSQAV-------RQTPP-----YQEPGTQTSPL 4253

Query: 871  AGNPGSDYFPGGTAPGAPGP-GGPSGTSSSGSKASGPPNPPAQGDGTSLSP 920
             G  G     G    G PGP  GP     +G +  GPP  PA     S  P
Sbjct: 4254 QGLLGCQPQLG----GFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGP 4300



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 195/834 (23%), Positives = 265/834 (31%), Gaps = 189/834 (22%)

Query: 37   PAFHTGGPPGPVDPAMS-ALGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQ 95
            P F T  P  P  P+ + A  +PP+LG +  P                         G  
Sbjct: 2187 PRFPTAPPTYPPYPSPTGAPAQPPMLGASSRP-------------------------GAG 2221

Query: 96   QPHHGHPGSHHPHQHHPHFGGNFGGPD-PGASCLHGGRLLGYGG--AAGGLGSQPPFAEG 152
            QP   H       +H P     F  P  P    L      G GG  A+  L S PPF E 
Sbjct: 2222 QPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGES 2281

Query: 153  ---YEHMAESQGPES--FGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLP 207
                E   E  G  S  +GP   G + D  SSG     +      + ++P    +    P
Sbjct: 2282 RKALEVKKEELGASSPSYGPPNLGFV-DSPSSGTHLGGLELKTPDVFKAPLTPRASQVEP 2340

Query: 208  SSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSP---SDSEGQLPHYAAGRQ 264
             S G      EP     Q    S         P  H D+F P   +D   Q P     R 
Sbjct: 2341 QSPGLGLRPQEPPPA--QALAPS---------PPSHPDIFRPGSYTDPYAQPP--LTPRP 2387

Query: 265  VPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMP 324
             P       +  PR+      S++ A P     Q Q   Q       +  E F      P
Sbjct: 2388 QPPPPESCCALPPRSLPSDPFSRVPASP-----QSQSSSQSPLTPRPLSAEAFC-----P 2437

Query: 325  VGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPP---PPGLLVRQN----SCPPA 377
              + P   S  P  +PP +        P  +PP+ QPP      G L   +      P A
Sbjct: 2438 SPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAA 2497

Query: 378  LPRPQQGE--AGTPSGGLQD-------GGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFS 428
            LP    GE  A  PSG   +       G  +      +F +P             EP  S
Sbjct: 2498 LPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFP---------QAVGEP--S 2546

Query: 429  MQHPPPQQA---PNQRLQHFDAPPYMNVAKRPRFD------FPGSAGVDRCASWNGSMHN 479
            ++ P PQ     P+    HF   P +   +   +        P  + +   +   G  + 
Sbjct: 2547 LKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYG 2606

Query: 480  GALDNHLSPSAYPGLPGEFTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQ-------- 531
                  LSP   P +     PP PD   S P L H A     +    ++++         
Sbjct: 2607 ------LSPLRPPSV---LPPPAPDG--SLPYLSHGASQRSGITSPVEKREDPGTGMGSS 2655

Query: 532  ---------QQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHPG 582
                     Q        Q + ++Q+Q+++   L+I+Q   RN  ++ ++   A  G  G
Sbjct: 2656 LATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVG 2715

Query: 583  DVGQGGLVHGGPVGGLAQPNFEREGGSTGAGRLGTFEQQAPHLAQESAWFSGPHPPPG-- 640
              G  G     P                       FEQ    L++    F+G        
Sbjct: 2716 PPGSWGAEPSSP----------------------AFEQ----LSRGQTPFAGTQDKSSLV 2749

Query: 641  DLLPRRMGGSGLPADCGPHDPSLAPPPPPG-------GSGVLFRGPLQEPMRMPGEGHVP 693
             L P ++ G  L     P D  L+ PPPP         S  L  G      R P  G +P
Sbjct: 2750 GLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLP 2809

Query: 694  ALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERRP--PPPDFATSALGGQPGFPFGAA 751
             L     Q       L Q Q   A   +  A S R P  P P+    ALG     P    
Sbjct: 2810 -LQQQQQQ-------LWQQQQATAATSMRFAMSARFPSTPGPELGRQALGS----PLAGI 2857

Query: 752  GRQSTPHSGPGVNSPPSAGGG-------GGSSGGGGGGGAYPPQ-----PDFQP 793
               ST   GPG   P  AG             G G GG  +P Q     P F P
Sbjct: 2858 ---STRLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYP 2908



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 208/965 (21%), Positives = 291/965 (30%), Gaps = 199/965 (20%)

Query: 141  GGLGSQPPFAEGYEHMAESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRA 200
            G LGS PP A     +     P        G L             PA  +P   SP   
Sbjct: 2111 GALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKP-----------PAGSVPGPDSPGEL 2159

Query: 201  ASFHGLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYA 260
              F  LP    +   S +P  +        LE  +P  AP  +    SP+ +  Q P   
Sbjct: 2160 --FLKLPPQVPAQVPSQDPFGLA---PAYPLEPRFP-TAPPTYPPYPSPTGAPAQPPMLG 2213

Query: 261  AGRQVPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGA 320
            A  + PG   PG              + H  PP     Q   P    +       R    
Sbjct: 2214 ASSR-PGAGQPG--------------EFHTTPPGTPRHQPSTPDPFLKP------RCPSL 2252

Query: 321  RKMPVGLEPSVG---SRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPA 377
              + V   P VG   +  PL+ PP    P  + +   +  +++            +  P+
Sbjct: 2253 DNLAVPESPGVGGGKASEPLLSPP----PFGESRKALEVKKEE----------LGASSPS 2298

Query: 378  LPRPQQGEAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQA 437
               P  G   +PS G   GG                LE ++   +  P+         Q+
Sbjct: 2299 YGPPNLGFVDSPSSGTHLGG----------------LELKTPDVFKAPLTPRASQVEPQS 2342

Query: 438  PNQRLQHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGE 497
            P   L+  + PP   +A  P    P    + R  S+              P A P L   
Sbjct: 2343 PGLGLRPQEPPPAQALAPSP----PSHPDIFRPGSYT------------DPYAQPPLTPR 2386

Query: 498  FTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQ--------------------QQ 537
              PP P+S  + PP   P+     +    Q Q   Q                      Q 
Sbjct: 2387 PQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQS 2446

Query: 538  QQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGL---VHGGP 594
                 +   + Q R   A + K    +  +   +  +LA       +G GG    +  GP
Sbjct: 2447 PDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHT----SLGAGGFPAALPAGP 2502

Query: 595  VGGL-------AQPNFEREGGSTGA--GRLGTFEQQAPHLAQESAWFSGPHPPPGDLLPR 645
             G L         PNF R  G TGA  G         P    E +    P P PG   P 
Sbjct: 2503 AGELHAKVPSGQPPNFVRSPG-TGAFVGTPSPMRFTFPQAVGEPS-LKPPVPQPGLPPPH 2560

Query: 646  RMGGSGLPAD-------------CGPHDPSLAPPPPPGGSGVLFRG--PLQEPMRMP--- 687
             +     P                G   PS +P  P  GS     G  PL+ P  +P   
Sbjct: 2561 GINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPA 2620

Query: 688  GEGHVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALGGQPGFP 747
             +G +P L     Q  G    + + + PG G+G  S A+   P   D   S L       
Sbjct: 2621 PDGSLPYLSHGASQRSGITSPVEKREDPGTGMG-SSLATAELPGTQDPGMSGLSQTELEK 2679

Query: 748  FGAAGR------QSTPHSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSA-- 799
                 R      +             +A    G+ G  G  GA P  P F+   R     
Sbjct: 2680 QRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPF 2739

Query: 800  --------------SKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLN 845
                          SKL    LG  + PS  D L      A  S+   N    +G    +
Sbjct: 2740 AGTQDKSSLVGLPPSKLSGPILGPGSFPSD-DRLSRPPPPATPSSMDVNSRQLVGG---S 2795

Query: 846  VTFNKKNPPEGKRKLSQNET---DGAAVAGNPGSDYFPGGTAPGAPGP-------GGPSG 895
              F ++ P  G   L Q +                +      P  PGP       G P  
Sbjct: 2796 QAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLA 2855

Query: 896  TSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSP 955
              S+     G P P   G    +   + ++   G  G P  G G   R R    S     
Sbjct: 2856 GISTRLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSE---- 2911

Query: 956  GTFFDKYSAAPD---SGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGK 1012
                D +  AP+        G+ P +  A  A    +S       PTPH K  T P+   
Sbjct: 2912 ----DPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSL-----HPTPHTKGPTLPT--- 2959

Query: 1013 GAELL 1017
            G EL+
Sbjct: 2960 GLELV 2964



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 191/912 (20%), Positives = 281/912 (30%), Gaps = 148/912 (16%)

Query: 145  SQPPFAEGYEHMAES--QGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAAS 202
            S PP +  +  + ES    PE   P      P      AS  + P    PL   P     
Sbjct: 504  SPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEE--- 560

Query: 203  FHGLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAAG 262
               LP+S   ++  L P    +           P   P     M  P ++    P +   
Sbjct: 561  ---LPTSPPPEASRLSPPPEES-----------PMSPPPEESPMSPPPEASRLFPPFEES 606

Query: 263  RQVPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARK 322
               P       S  P A+ +         PP +       P++          R S    
Sbjct: 607  PLSPPPEESPLSPPPEASRL--------SPPPEDSPMSPPPEESPMSPPPEVSRLS---P 655

Query: 323  MPV--GLEPSVGSRHPLMQPPQQAP--PPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPAL 378
            +PV   L P      PL  PP+++P  PPP+      PP+  P  PP          PA 
Sbjct: 656  LPVVSRLSPPP-EESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPP------EDSPAS 708

Query: 379  PRPQQGEAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAP 438
            P P+      P     +  P+LP        P     + S  P  EP  S +   P  +P
Sbjct: 709  PPPEDSLMSLPL----EESPLLPLPEEPQLCPRSEGPHLSPRP-EEPHLSPRPEEPHLSP 763

Query: 439  NQRLQHF----DAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGAL--DNHLSPSAYP 492
                 H     + P    V + P    P + G    +     +H      + HLSP    
Sbjct: 764  QAEEPHLSPQPEEPCLCAVPEEPHLS-PQAEG-PHLSPQPEELHLSPQTEEPHLSP---- 817

Query: 493  GLPGE-FTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQR 551
             +P E    P P+     P  + P    +  +     + ++     + ++  ++  Q   
Sbjct: 818  -VPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPA 876

Query: 552  QNAALMIKQMASRNQQQRLRQPNLAQLGHP-----------GDVGQGGLVHG-------- 592
                 +       +    L +P L++ G P              G+  L           
Sbjct: 877  PEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLP 936

Query: 593  ---------------GPVGGLAQPNFEREGGSTGAGRLGTFEQQAPHLAQESAWFSGPHP 637
                            P+G L  P F  +G S     L     + P      A  + P P
Sbjct: 937  PPLSPIITAAAPPALSPLGELEYP-FGAKGDSDPESPLAAPILETPISPPPEANCTDPEP 995

Query: 638  PPGDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRG--PLQEPMRMPGEGHVPAL 695
             P  +LP   G     +  GP  P L  P PP  S +L     P   P   P +   PAL
Sbjct: 996  VPPMILPPSPG-----SPVGPASPILMEPLPPQCSPLLQHSLVPQNSP---PSQCSPPAL 1047

Query: 696  PSPGLQFGGSLGGLGQLQSPGAGVGLPSAASER--RPPPPDFATSALGGQPGFPFGAAGR 753
            P   L     L  +G++        L    +E+   P  P    SA    P  P G    
Sbjct: 1048 P---LSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPS-PMGDLSC 1103

Query: 754  QSTPHSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKP 813
             + P   P ++     G       G    G+ P +P   P    S  K   + L      
Sbjct: 1104 PA-PSPAPALDDFSGLGEDTAPLDGIDAPGSQP-EPGQTPGSLASELKGSPVLLDPEELA 1161

Query: 814  SSKDNLFGQSC--LAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNE----TDG 867
                      C   A   + C+        P   V      PP   +    NE    + G
Sbjct: 1162 PVTPMEVYPECKQTAGQGSPCEEQ----EEPRAPVA---PTPPTLIKSDIVNEISNLSQG 1214

Query: 868  AAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLEST 927
             A A  PGS+        G+P P G  G S S          PA+ +G+      +L  T
Sbjct: 1215 DASASFPGSE-----PLLGSPDPEG--GGSLSMELGVSTDVSPARDEGSLRLCTDSLPET 1267

Query: 928  SGN----DGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASG 983
              +     G  +SGG   G   R+R S            + +    G     PG+++  G
Sbjct: 1268 DDSLLCDAGTAISGGKAEGEKGRRRSSP-----------ARSRIKQGRSSSFPGRRRPRG 1316

Query: 984  AAVGGSSAGETR 995
             A GG   G  R
Sbjct: 1317 GAHGGRGRGRAR 1328



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 46/138 (33%), Positives = 62/138 (44%), Gaps = 13/138 (9%)

Query: 518  DHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRL--RQPNL 575
            D    QQ++      + + +QQQQQQQQQQQQQ+ +A L +    S +Q  RL  + P  
Sbjct: 3579 DQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLAL----SPSQSPRLLTKLPGQ 3634

Query: 576  AQLGHPGDVGQGGLVHGGPVGGL-AQPNFEREGGSTGAGRLGT--FEQQAPHLAQESAWF 632
               GH     QG    GG  GGL   P      G  G   L T   +QQ    +  +   
Sbjct: 3635 LLPGHGLQPPQG--PPGGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSGGAGSL 3692

Query: 633  SGPHPP--PGDLLPRRMG 648
            +GP     PG+L  R +G
Sbjct: 3693 AGPSGGFFPGNLALRSLG 3710



 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 87/426 (20%), Positives = 140/426 (32%), Gaps = 80/426 (18%)

Query: 160 QGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDSHSLEP 219
           + P S  P+     P   +S  S      P  PL ++ + +      P S   +   L P
Sbjct: 446 ESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSP 505

Query: 220 RRVTNQ-GAVDSLEYNYPGEAPSG---HFDMFSPSDSEGQLPHYAAGRQVPGGAFPGASA 275
              ++    ++    + P E+P        +  P ++    P +      P       S 
Sbjct: 506 PPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSP 565

Query: 276 MPRAAGMVGLSKMHAQPPQQQPQQ---QQQPQQQQQQHGVFFERFSGARKMPVGLE---- 328
            P A+ +       + PP++ P     ++ P     +    F  F  +   P   E    
Sbjct: 566 PPEASRL-------SPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLS 618

Query: 329 -PSVGSR-------HPLMQPPQQAP--------------------PPPQQQPPQQPPQQQ 360
            P   SR        P+  PP+++P                    PPP++ P   PP++ 
Sbjct: 619 PPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEES 678

Query: 361 PPPPPGLLVRQNSCP---PALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFEYPIHRL-EN 416
           P  PP    R +  P   P  P P+   A  P    +D    LP +    E P+  L E 
Sbjct: 679 PTSPPPEASRLSPPPEDSPTSPPPEDSPASPPP---EDSLMSLPLE----ESPLLPLPEE 731

Query: 417 RSMHPYSE-PVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNG 475
             + P SE P  S +   P  +P     H  +P        P+ + P    V        
Sbjct: 732 PQLCPRSEGPHLSPRPEEPHLSPRPEEPHL-SPQAEEPHLSPQPEEPCLCAVPE------ 784

Query: 476 SMHNGALDNHLSPSAYPGLPGEFTPPVPDSFPSGP----PLQHPAPDHQSLQQQQQQQQQ 531
                  + HLSP A     G    P P+     P    P   P P+   L  Q ++   
Sbjct: 785 -------EPHLSPQA----EGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHL 833

Query: 532 QQQQQQ 537
             Q ++
Sbjct: 834 SPQSEE 839



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 53/223 (23%), Positives = 80/223 (35%), Gaps = 27/223 (12%)

Query: 294 QQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQPP 353
           Q QP+       Q ++ G          K  V LEP + +  PL +      PPP++ P 
Sbjct: 393 QGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEA--PLNEE-MPLLPPPEESPL 449

Query: 354 QQPPQQQPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFEYPIHR 413
             PP++ P  PP    R +  P  LP     EA   S  L++     P + +    P   
Sbjct: 450 SPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPP--- 506

Query: 414 LENRSMHPYSEPVFSMQHPPPQQAPNQRLQ-HFDAPPYMNVAKRPRFDFPGSAGVDRCAS 472
            E+    P  E   S   PP +  P+  L+     PP  +    P  + P S   +    
Sbjct: 507 PESSPFSPLEESPLS---PPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEEL-- 561

Query: 473 WNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSFPSGPPLQHP 515
                          P++ P      +PP  +S  S PP + P
Sbjct: 562 ---------------PTSPPPEASRLSPPPEESPMSPPPEESP 589



 Score = 35.0 bits (79), Expect = 0.48
 Identities = 50/161 (31%), Positives = 63/161 (39%), Gaps = 21/161 (13%)

Query: 285  LSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERF-SGARKMP-VGLEPSV-GSRHPLMQPP 341
            L K      Q QP QQQ  QQQQQQH +      + A  +P  G  PS+ GS+  L    
Sbjct: 3260 LQKKQQLSAQLQPAQQQ--QQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQQLSLGL 3317

Query: 342  QQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLP 401
              A  P   QP        P  PP   ++Q   P       QG   +   G Q G  ++P
Sbjct: 3318 AGARQPGLPQP------LMPTQPPAHALQQRLAPSMAMVSNQGHMLSGQHGGQAG--LVP 3369

Query: 402  SQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRL 442
             Q +Q   P+      S  P      SM   P Q A  Q+L
Sbjct: 3370 QQSSQ---PV-----LSQKPMGTMPPSMCMKPQQLAMQQQL 3402



 Score = 33.9 bits (76), Expect = 1.1
 Identities = 15/37 (40%), Positives = 26/37 (70%)

Query: 520  QSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAAL 556
            + L + ++++ Q++QQ   Q Q  QQQQQQQ+Q++ L
Sbjct: 3250 EDLLEHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLL 3286



 Score = 33.9 bits (76), Expect = 1.1
 Identities = 14/35 (40%), Positives = 20/35 (57%)

Query: 328  EPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPP 362
            EP V S  PL   P+ A P P+ +PP++    +PP
Sbjct: 4943 EPPVPSPLPLASSPESARPKPRARPPEEGEDSRPP 4977



 Score = 33.5 bits (75), Expect = 1.4
 Identities = 15/29 (51%), Positives = 20/29 (68%)

Query: 518  DHQSLQQQQQQQQQQQQQQQQQQQQQQQQ 546
            +H+  + Q++QQ   Q Q  QQQQQQQQQ
Sbjct: 3254 EHEKKELQKKQQLSAQLQPAQQQQQQQQQ 3282



 Score = 33.1 bits (74), Expect = 1.8
 Identities = 27/75 (36%), Positives = 31/75 (41%), Gaps = 9/75 (12%)

Query: 512  LQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAAL----MIKQMASRNQQ 567
            L+H   + Q  QQ   Q Q  QQQQQQQQQ          Q  +L        +A   QQ
Sbjct: 3253 LEHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQQ 3312

Query: 568  QRL-----RQPNLAQ 577
              L     RQP L Q
Sbjct: 3313 LSLGLAGARQPGLPQ 3327



 Score = 33.1 bits (74), Expect = 1.8
 Identities = 39/130 (30%), Positives = 45/130 (34%), Gaps = 25/130 (19%)

Query: 236  PGEAPSGHFDMFSPS--DSEGQLPHYAAGRQVPGGAFPGASAMPRAAGMVGLSKMHAQPP 293
            P +A S   +  SPS   S+ QL    AG + PG   P                M  QPP
Sbjct: 3291 PAQAMSLPHEGSSPSLAGSQQQLSLGLAGARQPGLPQP---------------LMPTQPP 3335

Query: 294  QQQPQQQQQPQQ---QQQQHGVFFERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQ 350
                QQ+  P       Q H       SG      GL P   S+  L Q P    PP   
Sbjct: 3336 AHALQQRLAPSMAMVSNQGH-----MLSGQHGGQAGLVPQQSSQPVLSQKPMGTMPPSMC 3390

Query: 351  QPPQQPPQQQ 360
              PQQ   QQ
Sbjct: 3391 MKPQQLAMQQ 3400



 Score = 32.7 bits (73), Expect = 2.4
 Identities = 104/453 (22%), Positives = 143/453 (31%), Gaps = 81/453 (17%)

Query: 96   QPHHGHPGSHHPHQHHPHFGGN--FGGPDPGASCLHGGRLLGYGGAAGGLGSQPPFAEGY 153
            +P    PG   PH  + HFG     G P      +  G     G   G   S     E Y
Sbjct: 2548 KPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGP--SSGSTGESY 2605

Query: 154  EHMAESQGPESFGPQRP-GNLPDFHSSGASSHAVPAPCLPLDQSPNRA-------ASFHG 205
              ++  + P    P  P G+LP + S GAS  +     +   + P          A   G
Sbjct: 2606 G-LSPLRPPSVLPPPAPDGSLP-YLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPG 2663

Query: 206  L--PSSSGSDSHSLEPRRVTNQ-------GAVDSLEYNYPGEAPSGHFDMFSPSDSEGQL 256
               P  SG     LE +R   +         +         E  +       P  S G  
Sbjct: 2664 TQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAE 2723

Query: 257  PHYAAGRQVPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFER 316
            P   A  Q+  G  P A    +++ +VGL       P   P       +  +        
Sbjct: 2724 PSSPAFEQLSRGQTPFAGTQDKSS-LVGLPPSKLSGPILGPGSFPSDDRLSRPPPP---- 2778

Query: 317  FSGARKMPVGLEPSVGSRHPLMQ-PPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCP 375
             +    M V     VG      Q  P     P QQQ  Q   QQQ      +    ++  
Sbjct: 2779 -ATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARF 2837

Query: 376  PALPRPQQGE--AGTPSGGLQ-----DGGPML-PSQHAQFEYPIHRLENRSMHPYSEPVF 427
            P+ P P+ G    G+P  G+       G P+  P+  AQF    H ++ + + P   P F
Sbjct: 2838 PSTPGPELGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIELRHNVQ-KGLGPGGTP-F 2895

Query: 428  SMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLS 487
              Q PP                     +RPRF +P S    R                L+
Sbjct: 2896 PGQGPP---------------------QRPRF-YPVSEDPHR----------------LA 2917

Query: 488  PSAYPGLPGEFTPPVPDSFPSGPPLQ---HPAP 517
            P    GL     PP   S P  P L    HP P
Sbjct: 2918 PEGLRGLAVSGLPPQKPSAPPAPELNNSLHPTP 2950



 Score = 30.8 bits (68), Expect = 9.0
 Identities = 39/139 (28%), Positives = 47/139 (33%), Gaps = 30/139 (21%)

Query: 637 PPPGDL----LPRRMGGSG----LPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPG 688
           PPP +L    LP  +  S      P    P +  L+PPP       L   PL  P   P 
Sbjct: 469 PPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESP- 527

Query: 689 EGHVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALGGQPGFPF 748
                  PSP L+   S        SP      P   S   PPP +  TS        P 
Sbjct: 528 -------PSPALETPLSPPPEASPLSP------PFEESPLSPPPEELPTS--------PP 566

Query: 749 GAAGRQSTPHSGPGVNSPP 767
             A R S P     ++ PP
Sbjct: 567 PEASRLSPPPEESPMSPPP 585


>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
          Length = 1745

 Score = 91.3 bits (225), Expect = 6e-18
 Identities = 251/1097 (22%), Positives = 344/1097 (31%), Gaps = 241/1097 (21%)

Query: 138  GAAGGLGSQPPFAEG--YEHMAESQGPESF-GPQRPGNLPDFHSSGASSHAVPAPCLPLD 194
            G  G  G      +G  +E    + GP+   GP  P   P F               P D
Sbjct: 373  GEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVGPSGPPGPPGF---------------PGD 417

Query: 195  QSPNRAASFHGLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEG 254
              P   A   GLP   G D     P      G V  + + + G +  G    F  + ++ 
Sbjct: 418  PGPPGPA---GLPGIPGIDGIRGPP------GTVIMMPFQFAGGSFKGPPVSFQQAQAQA 468

Query: 255  QLPHYAAGRQVPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHG--- 311
             L       + P    PG   +    G VGL        ++  +  Q P+  Q  HG   
Sbjct: 469  VLQQTQLSMKGP----PGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPG 524

Query: 312  ----VFFERFSGARKMP--------------VGLEPSVGSRHPLMQPPQQAPPPPQQQ-- 351
                +      GAR +P               GL    G R       Q  PP    +  
Sbjct: 525  RVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERG 584

Query: 352  ---PPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFE 408
               PP    Q   P P GLL          PR   G  G P     DG P          
Sbjct: 585  AEGPPGPTGQAGEPGPRGLLG---------PRGSPGPTGRPGVTGIDGAPGAKG------ 629

Query: 409  YPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFPGSAGVD 468
                     ++ P  EP       PP Q  N   Q    P  + +        PG+ G+ 
Sbjct: 630  ---------NVGPPGEP------GPPGQQGNHGSQGLPGPQGL-IGTPGEKGPPGNPGIP 673

Query: 469  RCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQ 528
                 +G + +   +         G PG   PP    +P GP        ++ LQ ++ +
Sbjct: 674  GLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPP---GYP-GPRGVKGTSGNRGLQGEKGE 729

Query: 529  Q----------------QQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQ 572
            +                 Q +      + +   +  + +   A       S  ++ +L  
Sbjct: 730  KGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGV 789

Query: 573  PNLAQLGHPGDVG-QGGLVHGGPVGGLA---------QPNFEREGGSTGA----GRLGTF 618
            P L   G+PG  G +G +   GP+G +          QP  E E G  G+    G+ G  
Sbjct: 790  PGLP--GYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGAT 847

Query: 619  EQQAPH--LAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGP--HDPSLAPPPPPGGSGV 674
             Q  P   + Q+ A    P  P    LP   G  G P   GP  H      P  PG  G 
Sbjct: 848  GQPGPKGDVGQDGA----PGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGE 903

Query: 675  L-FRGPLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPPP 733
            L F+G    P      G    L   G    G +G LG+   PG     P    E+  P  
Sbjct: 904  LGFQGQTGPP------GPAGVLGPQGKT--GEVGPLGERGPPGP----PGPPGEQGLPGL 951

Query: 734  DFATSALG--GQPGFPFGAAGRQST-----PHSGPGVNSPPSAGGGGGSSGGGGGGGAYP 786
            +    A G  G PG P G  G         P  GPG   P    G  G  G  G  G+  
Sbjct: 952  EGREGAKGELGPPG-PLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGS-- 1008

Query: 787  PQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNV 846
                  P +R      G + L             GQS               +G      
Sbjct: 1009 ------PGERGPLGPAGGIGLP------------GQS----------GSEGPVGPAGKKG 1040

Query: 847  TFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAP-GAPGPGGPSGTSSSGSKASG 905
            +  ++ PP                 G  G D  PG   P G PG  GPSG          
Sbjct: 1041 SRGERGPP-----------------GPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGA 1083

Query: 906  PPNPPAQGDGTSLSP--NYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYS 963
            P +  ++GD     P     +   +G+ G P + G    RG          PG F  K  
Sbjct: 1084 PGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRG---------PPGLFGQK-- 1132

Query: 964  AAPDSG--------GAPGVS--PGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKG 1013
               D G        G PG+   PG     G  VG   +    GAP P  +    P+  +G
Sbjct: 1133 --GDDGVRGFVGVIGPPGLQGLPGPPGEKGE-VGDVGSMGPHGAPGP--RGPQGPTGSEG 1187

Query: 1014 AELLLGD--QPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVK 1071
               L G   QP  +G  + G + D+  P  G   +  +     +  E   S  +  A   
Sbjct: 1188 TPGLPGGVGQPGAVG--EKGERGDAGDP--GPPGAPGIPGPKGDIGEKGDSGPSGAAGPP 1243

Query: 1072 ASRSPLVTGSPK--LPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGP---GH 1126
              + P      K  + P G+  G+ GP   P   G+         P   GG G P   G 
Sbjct: 1244 GKKGPPGEDGAKGSVGPTGL-PGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGE 1302

Query: 1127 PGTPGLEQVRTPTSSSG 1143
            PG PG    R P+   G
Sbjct: 1303 PGAPGPPGKRGPSGHMG 1319



 Score = 91.3 bits (225), Expect = 6e-18
 Identities = 300/1198 (25%), Positives = 366/1198 (30%), Gaps = 241/1198 (20%)

Query: 43   GPPGPVD----PAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPH 98
            GPPGP      P +  +  PP   + M P+ F             QAQ        Q   
Sbjct: 419  GPPGPAGLPGIPGIDGIRGPPGTVIMM-PFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSM 477

Query: 99   HGHPGSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHMAE 158
             G PG            G  G P P         L G+ G  G  G     AEG +    
Sbjct: 478  KGPPGPV----------GLTGRPGPVG-------LPGHPGLKGEEG-----AEGPQGPRG 515

Query: 159  SQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDSHSLE 218
             QGP   GP  PG +      GA      A  LP D  P     F GLP   G      +
Sbjct: 516  LQGPH--GP--PGRVGKMGRPGADG----ARGLPGDTGPKGDRGFDGLPGLPGEKGQRGD 567

Query: 219  PRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAAGRQVPGGAFPGASAMPR 278
               V   G         PGE   G      P    GQ     AG   P G   G    P 
Sbjct: 568  FGHVGQPGP--------PGE--DGERGAEGPPGPTGQ-----AGEPGPRGLL-GPRGSPG 611

Query: 279  AAGMVGLSKMHAQPPQQQ---PQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRH 335
              G  G++ +   P  +    P  +  P  QQ  HG      S     P GL  + G + 
Sbjct: 612  PTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHG------SQGLPGPQGLIGTPGEKG 665

Query: 336  PLMQPPQQAPP--------PPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQ----- 382
            P   P     P        P  + P  +   Q PP   G        PP  P P+     
Sbjct: 666  PPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAG--------PPGYPGPRGVKGT 717

Query: 383  ------QGEAGTPSGGLQDGGPM------LPSQHAQFEYPIHRLENRSMHPYSEPVFSMQ 430
                  QGE G      +DG P       L     +   P  R E+    P  +   + +
Sbjct: 718  SGNRGLQGEKGEKG---EDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGE 774

Query: 431  HPPPQQAPNQRLQHFDAPPYMNVAKRPR--FDFPGSAGVDRCASWNGSMHNGALDNHLSP 488
              PP  A  +        P       P+    FPG  G       +G      L+    P
Sbjct: 775  EGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGP 834

Query: 489  SAYPGLPGEFTPP--VPDSFPSGPPLQHPAPD---HQSLQQQQQQQQQQQQQQQQQQQQQ 543
               PG  GE   P       P G   Q  AP     + L   Q        +     Q +
Sbjct: 835  ---PGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGK 891

Query: 544  QQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGLVHG-GPVGGLAQPN 602
              +     Q   L  +          +  P   + G  G +G+ G     GP G    P 
Sbjct: 892  DGRPGHPGQRGELGFQGQTGPPGPAGVLGPQ-GKTGEVGPLGERGPPGPPGPPGEQGLPG 950

Query: 603  FE-REGGSTGAGRLGTFEQQAPHLAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPHDP 661
             E REG     G  G   ++ P   +    F GP   PGD      G +GL  D GP   
Sbjct: 951  LEGREGAKGELGPPGPLGKEGPAGLRG---FPGPKGGPGD-----PGPTGLKGDKGP--- 999

Query: 662  SLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGVGL 721
                P P G +G             PGE   P  P+ G+   G  G  G    P    G 
Sbjct: 1000 ----PGPVGANG------------SPGE-RGPLGPAGGIGLPGQSGSEG----PVGPAGK 1038

Query: 722  PSAASERRPPPP---DFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGG 778
              +  ER PP P   D     LG  P  P GAAG    P    G      A G  GS G 
Sbjct: 1039 KGSRGERGPPGPTGKDGIPGPLG--PLGPPGAAG----PSGEEGDKGDVGAPGHKGSKGD 1092

Query: 779  GGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIAS 838
             G  G     P  QP  R  A   G               LFGQ          +  +  
Sbjct: 1093 KGDAG-----PPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKG----DDGVRGFVGV 1143

Query: 839  LGAPNLNVTFNKKNPPEGKRKLS----------------QNETDGAAVAGNPGSDYFPGG 882
            +G P L        PP  K ++                 Q  T      G PG    PG 
Sbjct: 1144 IGPPGLQ---GLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGA 1200

Query: 883  TA-------------PGAPGPGGPSGT-----SSSGSKASGPPN---PPAQGDGTSLSPN 921
                           PGAPG  GP G       S  S A+GPP    PP + DG   S  
Sbjct: 1201 VGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGE-DGAKGSVG 1259

Query: 922  YTLESTSGNDGKPVSGG--GGRGRGRRKRDSGHVS-PGTFFDKYSAAPDSGGAPGVSPGQ 978
             T     G+ G P   G  G  G    K D G V  PG        A    GAPG  PG+
Sbjct: 1260 PT--GLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGP-----PGASGEPGAPG-PPGK 1311

Query: 979  QQASGAAVGGSSAGE--TRGAPTPH-EKALTSPSWGKGAELLLGDQ-----------PDL 1024
            +  SG        GE   +G P P      T P   +G    +G +           P L
Sbjct: 1312 RGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGL 1371

Query: 1025 IGSLDG----GAKSDSSSPNV-------GEFASDEVSTSYANEDEVSSSSDNPQALVKAS 1073
            +G+       G    S  P +       GE     +        E     D  Q L    
Sbjct: 1372 LGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGD--QGLPGVQ 1429

Query: 1074 RSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPG 1131
              P   G P  PP  +G+  H    PP   G      S  +P S G  G  G  G PG
Sbjct: 1430 GPPGPKGDPG-PPGPIGSLGH--PGPPGVAGPLGQKGSKGSPGSMGPRGDTGPAGPPG 1484



 Score = 82.8 bits (203), Expect = 2e-15
 Identities = 184/730 (25%), Positives = 223/730 (30%), Gaps = 192/730 (26%)

Query: 488  PSAYPGLPGEFTPPVPDSFPSGPPLQ--HPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQ 545
            P   PG PG+  PP P   P  P +      P    +   Q      +      QQ Q Q
Sbjct: 408  PPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQ 467

Query: 546  QQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFER 605
               QQ Q                      L+  G PG VG  G    GPVG    P  + 
Sbjct: 468  AVLQQTQ----------------------LSMKGPPGPVGLTG--RPGPVGLPGHPGLKG 503

Query: 606  EGGSTGAGRLGTFEQQAPHLAQESAWFSGPHPPPGDL----LPRRMGGSGLPADCGPHDP 661
            E G+ G         Q P   Q      GPH PPG +     P   G  GLP D G    
Sbjct: 504  EEGAEG--------PQGPRGLQ------GPHGPPGRVGKMGRPGADGARGLPGDTG---- 545

Query: 662  SLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGVGL 721
                  P G  G  F G             +P LP       G  G  G +  PG     
Sbjct: 546  ------PKGDRG--FDG-------------LPGLPGE----KGQRGDFGHVGQPGP---- 576

Query: 722  PSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGG 781
            P    ER    P   T    G+PG P G  G    P   PG    P   G  G+ G  G 
Sbjct: 577  PGEDGERGAEGPPGPTGQ-AGEPG-PRGLLG----PRGSPGPTGRPGVTGIDGAPGAKGN 630

Query: 782  GGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGA 841
             G  PP     P Q+ +         GS   P                          G 
Sbjct: 631  VG--PPGEPGPPGQQGNH--------GSQGLP--------------------------GP 654

Query: 842  PNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAP-GAPGPGGPSGTSSSG 900
              L  T  +K PP                 GNPG    PG   P G PG  GP+G   + 
Sbjct: 655  QGLIGTPGEKGPP-----------------GNPGIPGLPGSDGPLGHPGHEGPTGEKGAQ 697

Query: 901  SK--ASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTF 958
                ++GPP  P        S N  L+   G  G+     G +G    K D G   PG  
Sbjct: 698  GPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGED-GFPGFKGDVGLKGDQG--KPG-- 752

Query: 959  FDKYSAAPDSGGAPGVSPGQQQASGAAVGG--SSAGETRGAPTPHEKALTSPSWGKGAEL 1016
                  AP   G  G    + QA  A   G   SAGE      P           KG+  
Sbjct: 753  ------APGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGS-- 804

Query: 1017 LLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSP 1076
             +G  P  +G +    KS  +     E       +        ++    P+  V    +P
Sbjct: 805  -IG-FPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAP 862

Query: 1077 LVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVR 1136
             + G   LP      G  GPK P               P   G  G PGHPG  G    +
Sbjct: 863  GIPGEKGLPGLQGPPGFPGPKGP---------------PGHQGKDGRPGHPGQRGELGFQ 907

Query: 1137 TPTSSSGAPPPDEIHPLEILQAQIQLQRQQFSISEDQPLGLKG-----GKKGECAV-GAS 1190
              T   G  P   + P             Q    E  PLG +G     G  GE  + G  
Sbjct: 908  GQTGPPG--PAGVLGP-------------QGKTGEVGPLGERGPPGPPGPPGEQGLPGLE 952

Query: 1191 GAQNGDSELG 1200
            G +    ELG
Sbjct: 953  GREGAKGELG 962



 Score = 61.6 bits (148), Expect = 5e-09
 Identities = 168/687 (24%), Positives = 205/687 (29%), Gaps = 147/687 (21%)

Query: 579  GHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGA-GRLGTFEQQAPHLAQESAWFSGPHP 637
            G PG+ GQ G    G VG    P  + E G+ G  G  G   +  P          GP  
Sbjct: 557  GLPGEKGQRG--DFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPR------GLLGPRG 608

Query: 638  PPGDL-LPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRM---PGEGHVP 693
             PG    P   G  G P   G   P    P PPG  G      L  P  +   PGE   P
Sbjct: 609  SPGPTGRPGVTGIDGAPGAKGNVGPP-GEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPP 667

Query: 694  ALPS-PGLQFGGSLGGLGQLQSPG-----AGVGLPSAASERRPPPPDFATSALG------ 741
              P  PGL   GS G LG     G        G P +A     P P       G      
Sbjct: 668  GNPGIPGLP--GSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQG 725

Query: 742  -----GQPGFP-----FGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDF 791
                 G+ GFP      G  G Q  P    G   P    G  G  G  G  G   P    
Sbjct: 726  EKGEKGEDGFPGFKGDVGLKGDQGKP----GAPGPRGEDGPEGPKGQAGQAGEEGP---- 777

Query: 792  QPSQRTSASKLGALSLGSF-NKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNK 850
             P       KLG   L  +  +P  K ++     L  +    ++     G P L     +
Sbjct: 778  -PGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKS--GKTGQPGLE---GE 831

Query: 851  KNPPEGKRKLSQNETDGA----------AVAGNPGSDYFPGGTAP-GAPGPGGPSGTSSS 899
            + PP  + +  Q    G              G PG    PG   P G PGP GP G    
Sbjct: 832  RGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGK 891

Query: 900  GSKAS-----------------------------------------GPPNPPA------- 911
              +                                           GPP PP        
Sbjct: 892  DGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGL 951

Query: 912  ---QGDGTSLSPNYTL--ESTSGNDG--KPVSGGGGRGRGRRKRDSGHVSP----GTFFD 960
               +G    L P   L  E  +G  G   P  G G  G    K D G   P    G+  +
Sbjct: 952  EGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGE 1011

Query: 961  KYSAAPDSG-GAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEK-------ALTSPSWGK 1012
            +    P  G G PG S G +   G A    S GE RG P P  K           P    
Sbjct: 1012 RGPLGPAGGIGLPGQS-GSEGPVGPAGKKGSRGE-RGPPGPTGKDGIPGPLGPLGPPGAA 1069

Query: 1013 GAELLLGDQPDLIGSLDGGAKSDS------SSPNV-------GEFASDEVSTSYANEDEV 1059
            G     GD+ D+      G+K D         P +       G   +D            
Sbjct: 1070 GPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLF 1129

Query: 1060 SSSSDN-PQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSY 1118
                D+  +  V     P + G P  P      G+ G   P  A G       T +  + 
Sbjct: 1130 GQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTP 1189

Query: 1119 GGGGGPGHPGTPGLEQVRTPTSSSGAP 1145
            G  GG G PG  G +  R      G P
Sbjct: 1190 GLPGGVGQPGAVGEKGERGDAGDPGPP 1216



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 79/238 (33%), Positives = 92/238 (38%), Gaps = 47/238 (19%)

Query: 579  GHPGDVGQGGLVHG-GPVGGLAQPNFEREGGSTG-AGRLGTFEQQAPHLAQESAWFSGPH 636
            G PG+ G  G V G GP G   +P      G  G +G +G   ++    A+      GP 
Sbjct: 1280 GSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEP---GPD 1336

Query: 637  PPPGDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPALP 696
             PPG   P  MG  G P   GP    L   P P G   L   P Q  M  PG    P  P
Sbjct: 1337 GPPGRTGP--MGARGPPGRVGPE--GLRGIPGPVGEPGLLGAPGQ--MGPPG----PLGP 1386

Query: 697  S--PGLQFG-------GSLGGLGQLQSPGAG-----VGLPSAASERRPPPPDFATSALGG 742
            S  PGL+         G +G +G +  PG        GLP       PP P        G
Sbjct: 1387 SGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQG---PPGPK-------G 1436

Query: 743  QPGFPFGAAGRQSTPHSGP-GVNSPPSAGGGGGSSGG----GGGGGAYPPQPDFQPSQ 795
             PG P G  G  S  H GP GV  P    G  GS G     G  G A PP P   P++
Sbjct: 1437 DPGPP-GPIG--SLGHPGPPGVAGPLGQKGSKGSPGSMGPRGDTGPAGPPGPPGAPAE 1491



 Score = 41.2 bits (95), Expect = 0.007
 Identities = 110/420 (26%), Positives = 132/420 (31%), Gaps = 63/420 (15%)

Query: 35   KAPAFHTGGPPGPVDPAMSALGEPPILGMNMEPYGFHARGH-SELHAGGLQAQPVHGFFG 93
            + PA H G PPG  D A    G P + G   +      RG    +   GLQ  P      
Sbjct: 1105 RGPAGHPG-PPG-ADGAQGRRGPPGLFGQKGDD---GVRGFVGVIGPPGLQGLPGPP--- 1156

Query: 94   GQQPHHGHPGSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLGSQ------- 146
            G++   G  GS  PH      G        G   L GG  +G  GA G  G +       
Sbjct: 1157 GEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGG--VGQPGAVGEKGERGDAGDPG 1214

Query: 147  PPFAEGYE-------HMAESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNR 199
            PP A G            +S    + GP  PG        GA     P   LP D  P  
Sbjct: 1215 PPGAPGIPGPKGDIGEKGDSGPSGAAGP--PGKKGPPGEDGAKGSVGPTG-LPGDLGPPG 1271

Query: 200  AASFHGLPSSSGSDSHSLEPRRVTNQGAVD-SLEYNYPG----EAPSGHFDMFSPSDSEG 254
                 G+  S G      +P  V   G    S E   PG      PSGH         +G
Sbjct: 1272 DPGVSGIDGSPGEKG---DPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKG 1328

Query: 255  QL----PHYAAGRQVPGGAFP-----GASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQ 305
                  P    GR  P GA       G   +    G VG   +   P Q  P     P  
Sbjct: 1329 AKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSG 1388

Query: 306  QQQQHGVFFERFSGARKMPVGLEPSVGSRHPLMQPPQQAPP------PPQQQPPQQPPQQ 359
                 G   +      K  +GL   +G       PP +A        P  Q PP      
Sbjct: 1389 LPGLKG---DTGPKGEKGHIGLIGLIG-------PPGEAGEKGDQGLPGVQGPPGPKGDP 1438

Query: 360  QPPPPPGLLVRQNSCPPALPRPQQGEAGTPS--GGLQDGGPMLPSQHAQFEYPIHRLENR 417
             PP P G L        A P  Q+G  G+P   G   D GP  P         +H L  R
Sbjct: 1439 GPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGPRGDTGPAGPPGPPGAPAELHGLRRR 1498



 Score = 36.6 bits (83), Expect = 0.16
 Identities = 75/313 (23%), Positives = 109/313 (34%), Gaps = 57/313 (18%)

Query: 914  DGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPG 973
            D  +L+P  T+ +  G    P     G+G+GR+K   G    G    K      S   P 
Sbjct: 223  DCDNLAPAATV-APQGEPETPRPRRKGKGKGRKK---GRGRKGKGRKKNKEIWTSSPPPD 278

Query: 974  VSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSP-SWGKGAELLLGD-QPDL---IGSL 1028
             +  Q       +  +        PTP    +TS  + G  A +L     PD    +G+L
Sbjct: 279  SAENQTSTD---IPKTETPAPNLPPTPTPLVVTSTVTTGLNATILERSLDPDSGTELGTL 335

Query: 1029 DGGAKSDSSSPNVGEFASDEVSTSYANEDEVS--------SSSDNPQALVKASRSPLVTG 1080
            +  A  +    +      D  +  Y +  +           +   P  + K  +     G
Sbjct: 336  ETKAAREDEEGDDSTMGPDFRAAEYPSRTQFQIFPGAGEKGAKGEPAVIEKGQQFEGPPG 395

Query: 1081 SPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTS 1140
            +P   P+GV  G  GP  PP              P   G  G  G PG PG++ +R P  
Sbjct: 396  APG--PQGV-VGPSGPPGPP------------GFPGDPGPPGPAGLPGIPGIDGIRGPPG 440

Query: 1141 SSGAPP------PDEIHPLEILQAQIQLQRQQFSIS------------EDQPLGLKG--G 1180
            +    P        +  P+   QAQ Q   QQ  +S               P+GL G  G
Sbjct: 441  TVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPG 500

Query: 1181 KKGECAVGASGAQ 1193
             KGE   GA G Q
Sbjct: 501  LKGE--EGAEGPQ 511


>gi|194294532 alpha 1 type XIII collagen isoform 20 [Homo sapiens]
          Length = 717

 Score = 91.3 bits (225), Expect = 6e-18
 Identities = 137/503 (27%), Positives = 182/503 (36%), Gaps = 99/503 (19%)

Query: 681  QEPMRMPGEGHVPALPSPGLQFG-----GSLGGLGQLQSPG-AGVGLPSAASERRPPPPD 734
            + P   PG    P  P P  + G     G++G  G++ SPG AG+ +       R PP  
Sbjct: 109  EAPKTSPGCNCPPGPPGPTGRPGLPGDKGAIGMPGRVGSPGDAGLSIIGP----RGPPGQ 164

Query: 735  FATSALGGQPGFPFGAAGRQSTPHSGP----GVNSPPSAGGGGGSSGGGGGGGAYPPQPD 790
              T    G PG P G  G+    H GP    G+  PP   G  G  G  G  G YP +  
Sbjct: 165  PGTRGFPGFPG-PIGLDGKPG--HPGPKGDMGLTGPPGQPGPQGQKGEKGQCGEYPHR-- 219

Query: 791  FQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQN--MIASLGAPNLNVTF 848
                                             CL+++  A ++  +IA    P LN + 
Sbjct: 220  --------------------------------ECLSSMPAALRSSQIIALKLLPLLN-SV 246

Query: 849  NKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAP----GAPGPGGPSGTSSSGSKAS 904
                PP  KR+  Q E   A++ G PG    PG + P    G PGP GP G         
Sbjct: 247  RLAPPPVIKRRTFQGEQSQASIQGPPGPPGPPGPSGPLGHPGLPGPMGPPGLP------- 299

Query: 905  GPPNPPAQGDGTSLSPNYTLESTSGNDGKP----VSGGGGRGRGRRKRDSGHVSPGTFFD 960
            GPP P  +GD   +   +  +   G  G P      G  G      K + G   PGT  +
Sbjct: 300  GPPGP--KGD-PGIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEPG--IPGTKGE 354

Query: 961  KYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGD 1020
            K   A  S G PG+  GQ+   G A  G+S G  RG P P    L  P   KG   + G 
Sbjct: 355  K--GAEGSPGLPGLL-GQKGEKGDA--GNSIGGGRGEPGP--PGLPGPPGPKGEAGVDGQ 407

Query: 1021 -----QPDLIGSLDG-------GAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQA 1068
                 QP   G           G K     P  GE      + + A ++  + +   P  
Sbjct: 408  VGPPGQPGDKGERGAAGEQGPDGPKGSKGEPGKGEMVDYNGNINEALQEIRTLALMGPPG 467

Query: 1069 LVKASRSPLVTGSPK------LPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGG 1122
            L      P   G P       LP      GE GP+  P  +G              G  G
Sbjct: 468  LPGQIGPPGAPGIPGQKGEIGLPGPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKG 527

Query: 1123 GPGHPGTPGLEQVRTPTSSSGAP 1145
              GHPG+PG +  +  T  +G+P
Sbjct: 528  ENGHPGSPGEKGEKGETGQAGSP 550



 Score = 61.6 bits (148), Expect = 5e-09
 Identities = 146/574 (25%), Positives = 185/574 (32%), Gaps = 75/574 (13%)

Query: 593  GPVGGLAQPNFEREGGSTGA-GRLGTFEQQAPHLAQESAWFSGPHPPPGDLLPRRMGGSG 651
            GP G   +P    + G+ G  GR+G+     P  A  S    GP  PPG   P   G  G
Sbjct: 122  GPPGPTGRPGLPGDKGAIGMPGRVGS-----PGDAGLS--IIGPRGPPGQ--PGTRGFPG 172

Query: 652  LPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPALPS-PGLQFGGSLGGLG 710
             P   G  D     P P G  G+   GP  +P     +G        P  +   S+    
Sbjct: 173  FPGPIGL-DGKPGHPGPKGDMGLT--GPPGQPGPQGQKGEKGQCGEYPHRECLSSMPAAL 229

Query: 711  QLQSPGAGVGLPSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPPSAG 770
            +     A   LP   S R  PPP        G+          Q++    PG   PP   
Sbjct: 230  RSSQIIALKLLPLLNSVRLAPPPVIKRRTFQGEQS--------QASIQGPPGPPGPPGPS 281

Query: 771  GGGGSSGGGGGGGAY----PPQPDFQPSQRTSASKLGALSL-GSFNKPSSKDNLFGQSCL 825
            G  G  G  G  G      PP P   P  +    + G   + G   K  +K         
Sbjct: 282  GPLGHPGLPGPMGPPGLPGPPGPKGDPGIQGYHGRKGERGMPGMPGKHGAK--------- 332

Query: 826  AALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAP 885
             A   A   M    G P        +  P     L Q    G A     G    PG   P
Sbjct: 333  GAPGIAVAGMKGEPGIPGTKGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGRGEPG--PP 390

Query: 886  GAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGR 945
            G PGP GP G +    +  GPP  P        +     +   G+ G+P       G+G 
Sbjct: 391  GLPGPPGPKGEAGVDGQV-GPPGQPGDKGERGAAGEQGPDGPKGSKGEP-------GKGE 442

Query: 946  RKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKAL 1005
                +G+++      +  A     G PG+ PGQ    GA       GE  G P P     
Sbjct: 443  MVDYNGNINEALQEIRTLALM---GPPGL-PGQIGPPGAPGIPGQKGEI-GLPGP----- 492

Query: 1006 TSPSWGKGAELLLGDQ----PDLIGSLDG--GAKSDSSSPNVGEFASDEVSTSYAN---E 1056
                  KG     GD     P      DG  G K ++  P       ++  T  A    E
Sbjct: 493  PGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPGE 552

Query: 1057 DEVSSSSDNPQALVKASRSPLVTGSPKLP-------PRGVGAGEHGPKAPPPALGLGIMS 1109
               +    NP A V     P   G P  P       P+G  AG  G K      G     
Sbjct: 553  KGEAGEKGNPGAEVPGLPGP--EGPPGPPGLQGVPGPKGE-AGLDGAKGEKGFQGEKGDR 609

Query: 1110 NSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSG 1143
                 P + G  G PG PGTPG   V  P    G
Sbjct: 610  GPLGLPGASGLDGRPGPPGTPGPIGVPGPAGPKG 643



 Score = 57.4 bits (137), Expect = 9e-08
 Identities = 129/530 (24%), Positives = 167/530 (31%), Gaps = 88/530 (16%)

Query: 492 PGLPGEFTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQR 551
           PG PG    P  D   +GPP Q P P       Q Q+ ++ Q  +   ++         R
Sbjct: 183 PGHPG----PKGDMGLTGPPGQ-PGP-------QGQKGEKGQCGEYPHRECLSSMPAALR 230

Query: 552 QNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTG 611
            +  + +K +   N  +    P + +    G+  Q  +   GP G    P     G S  
Sbjct: 231 SSQIIALKLLPLLNSVRLAPPPVIKRRTFQGEQSQASIQ--GPPGPPGPP-----GPSGP 283

Query: 612 AGRLGTFEQQAPHLAQESAWFSGPHPPPGDL----LPRRMGGSGLPADCGPHDPSLAPPP 667
            G  G      P          GP  P GD        R G  G+P   G H    AP  
Sbjct: 284 LGHPGLPGPMGP------PGLPGPPGPKGDPGIQGYHGRKGERGMPGMPGKHGAKGAP-- 335

Query: 668 PPGGSGVLFRGPLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASE 727
                G+   G   EP     +G   A  SPGL   G LG  G+    G  +G       
Sbjct: 336 -----GIAVAGMKGEPGIPGTKGEKGAEGSPGLP--GLLGQKGEKGDAGNSIG----GGR 384

Query: 728 RRPPPPDFATSALGGQPGFPFGAAG--RQSTPHSGPGVNSPPSAGGGGGSSGGGGGGG-- 783
             P PP      L G PG P G AG   Q  P   PG      A G  G  G  G  G  
Sbjct: 385 GEPGPP-----GLPGPPG-PKGEAGVDGQVGPPGQPGDKGERGAAGEQGPDGPKGSKGEP 438

Query: 784 AYPPQPDFQPSQRTSASKLGALSL-------GSFNKPSSKDNLFGQSCLAAL-------- 828
                 D+  +   +  ++  L+L       G    P +   + GQ     L        
Sbjct: 439 GKGEMVDYNGNINEALQEIRTLALMGPPGLPGQIGPPGAP-GIPGQKGEIGLPGPPGHDG 497

Query: 829 STACQNMIASLGAPNLNVTFNKKNPPEGK----------RKLSQNETDGAAVAGNPGS-- 876
               +     +G P       K  PP  K           K  + ET  A   G  G   
Sbjct: 498 EKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPGEKGEAG 557

Query: 877 -DYFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPV 935
               PG   PG PGP GP G         G P P  +            +   G+ G P+
Sbjct: 558 EKGNPGAEVPGLPGPEGPPGPPG----LQGVPGPKGEAGLDGAKGEKGFQGEKGDRG-PL 612

Query: 936 SGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGAA 985
              G  G   R    G  +PG       A P         PG    +GAA
Sbjct: 613 GLPGASGLDGRPGPPG--TPGPIGVPGPAGPKGERGSKGDPGMTGPTGAA 660



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 100/383 (26%), Positives = 125/383 (32%), Gaps = 40/383 (10%)

Query: 579 GHPGDVGQGGLVHGGPVGGLAQPNFER--EGGSTGAGR--LGTFEQQAPHLAQESAWFSG 634
           G PG  G+ G      + GL     E+   G S G GR   G      P   +  A   G
Sbjct: 347 GIPGTKGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGRGEPGPPGLPGPPGPKGEAGVDG 406

Query: 635 PHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPA 694
              PPG   P   G  G   + GP  P  +   P  G  V + G + E ++   E    A
Sbjct: 407 QVGPPGQ--PGDKGERGAAGEQGPDGPKGSKGEPGKGEMVDYNGNINEALQ---EIRTLA 461

Query: 695 LPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALG--GQPGFPFGAAG 752
           L  P        G  GQ+  PGA  G+P    E   P P       G  G+PG   G  G
Sbjct: 462 LMGPP-------GLPGQIGPPGAP-GIPGQKGEIGLPGPPGHDGEKGPRGKPG-DMGPPG 512

Query: 753 RQSTP-HSGP----GVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSL 807
            Q  P   GP    G N  P + G  G  G  G  G+   + +        A   G    
Sbjct: 513 PQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPGEKGEAGEKGNPGAEVPGLPGP 572

Query: 808 GSFNKPSSKDNLFGQSCLAALSTAC--------QNMIASLGAPNLNVTFNKKNPPEGKRK 859
                P     + G    A L  A         +     LG P  +    +  PP     
Sbjct: 573 EGPPGPPGLQGVPGPKGEAGLDGAKGEKGFQGEKGDRGPLGLPGASGLDGRPGPPGTPGP 632

Query: 860 LSQNETDGAAVAGNPGSDYFPGGTAP----GAPGPGGPSGTSSS-GSKASGPPNPPAQGD 914
           +      G    G  GS   PG T P    G PG  GP G   + G +       P    
Sbjct: 633 IGVPGPAGPK--GERGSKGDPGMTGPTGAAGLPGLHGPPGDKGNRGERGKKGSRGPKGDK 690

Query: 915 GTSLSPNYTLESTSGNDGKPVSG 937
           G   +P        G DG PV G
Sbjct: 691 GDQGAPGLDAPCPLGEDGLPVQG 713



 Score = 35.8 bits (81), Expect = 0.28
 Identities = 92/355 (25%), Positives = 121/355 (34%), Gaps = 45/355 (12%)

Query: 43  GPPGPVDPAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQP-VHGFFG--GQQPHH 99
           GPPGP  P+   LG P + G  M P G            G +  P + G+ G  G++   
Sbjct: 273 GPPGPPGPS-GPLGHPGLPGP-MGPPGLPG-------PPGPKGDPGIQGYHGRKGERGMP 323

Query: 100 GHPGSHHPHQHHPHFG--GNFGGPD-PGASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHM 156
           G PG H   +  P     G  G P  PG     G    G  G  G LG +    +    +
Sbjct: 324 GMPGKHGA-KGAPGIAVAGMKGEPGIPGTKGEKGAE--GSPGLPGLLGQKGEKGDAGNSI 380

Query: 157 AESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDSHS 216
              +G E   P  PG       +G      P P  P D+    AA   G     GS    
Sbjct: 381 GGGRG-EPGPPGLPGPPGPKGEAGVDGQVGP-PGQPGDKGERGAAGEQGPDGPKGSKGEP 438

Query: 217 LEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQL-PHYAAGRQVPGGAFPGASA 275
            +   V   G ++         A  G      P    GQ+ P  A G  +PG    G   
Sbjct: 439 GKGEMVDYNGNINEALQEIRTLALMG------PPGLPGQIGPPGAPG--IPGQK--GEIG 488

Query: 276 MPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERF---SGARKMPVGLEPSVG 332
           +P   G  G      +P    P   Q P  +    GV  E     S   K   G     G
Sbjct: 489 LPGPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAG 548

Query: 333 SRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQGEAG 387
           S     +  ++  P  +   P  P  + PP PPGL          +P P +GEAG
Sbjct: 549 SPGEKGEAGEKGNPGAEV--PGLPGPEGPPGPPGL--------QGVPGP-KGEAG 592


>gi|22027583 alpha 1 type XIII collagen isoform 7 [Homo sapiens]
          Length = 703

 Score = 90.9 bits (224), Expect = 7e-18
 Identities = 137/503 (27%), Positives = 182/503 (36%), Gaps = 99/503 (19%)

Query: 681  QEPMRMPGEGHVPALPSPGLQFG-----GSLGGLGQLQSPG-AGVGLPSAASERRPPPPD 734
            + P   PG    PA   P  + G     G++G  G++ SPG AG+ +       R PP  
Sbjct: 109  EAPKTSPGCNCPPAFQGPTGRPGLPGDKGAIGMPGRVGSPGDAGLSIIGP----RGPPGQ 164

Query: 735  FATSALGGQPGFPFGAAGRQSTPHSGP----GVNSPPSAGGGGGSSGGGGGGGAYPPQPD 790
              T    G PG P G  G+    H GP    G+  PP   G  G  G  G  G YP +  
Sbjct: 165  PGTRGFPGFPG-PIGLDGKPG--HPGPKGDMGLTGPPGQPGPQGQKGEKGQCGEYPHR-- 219

Query: 791  FQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQN--MIASLGAPNLNVTF 848
                                             CL+++  A ++  +IA    P LN + 
Sbjct: 220  --------------------------------ECLSSMPAALRSSQIIALKLLPLLN-SV 246

Query: 849  NKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAP----GAPGPGGPSGTSSSGSKAS 904
                PP  KR+  Q E   A++ G PG    PG + P    G PGP GP G         
Sbjct: 247  RLAPPPVIKRRTFQGEQSQASIQGPPGPPGPPGPSGPLGHPGLPGPMGPPGLP------- 299

Query: 905  GPPNPPAQGDGTSLSPNYTLESTSGNDGKP----VSGGGGRGRGRRKRDSGHVSPGTFFD 960
            GPP P  +GD   +   +  +   G  G P      G  G      K + G   PGT  +
Sbjct: 300  GPPGP--KGD-PGIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEPG--IPGTKGE 354

Query: 961  KYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGD 1020
            K   A  S G PG+  GQ+   G A  G+S G  RG P P    L  P   KG   + G 
Sbjct: 355  K--GAEGSPGLPGLL-GQKGEKGDA--GNSIGGGRGEPGP--PGLPGPPGPKGEAGVDGQ 407

Query: 1021 -----QPDLIGSLDG-------GAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQA 1068
                 QP   G           G K     P  GE      + + A ++  + +   P  
Sbjct: 408  VGPPGQPGDKGERGAAGEQGPDGPKGSKGEPGKGEMVDYNGNINEALQEIRTLALMGPPG 467

Query: 1069 LVKASRSPLVTGSPK------LPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGG 1122
            L      P   G P       LP      GE GP+  P  +G              G  G
Sbjct: 468  LPGQIGPPGAPGIPGQKGEIGLPGPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKG 527

Query: 1123 GPGHPGTPGLEQVRTPTSSSGAP 1145
              GHPG+PG +  +  T  +G+P
Sbjct: 528  ENGHPGSPGEKGEKGETGQAGSP 550



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 143/553 (25%), Positives = 176/553 (31%), Gaps = 87/553 (15%)

Query: 632  FSGPHPPPGDLLPRRMGGSGLPADCG-PHDPSLA---PPPPPGGSGVL----FRGP--LQ 681
            F GP   PG  LP   G  G+P   G P D  L+   P  PPG  G      F GP  L 
Sbjct: 123  FQGPTGRPG--LPGDKGAIGMPGRVGSPGDAGLSIIGPRGPPGQPGTRGFPGFPGPIGLD 180

Query: 682  EPMRMPGEGHVPALPSPGLQFG--GSLGGLGQ---------LQSPGAGVG---------L 721
                 PG      L  P  Q G  G  G  GQ         L S  A +          L
Sbjct: 181  GKPGHPGPKGDMGLTGPPGQPGPQGQKGEKGQCGEYPHRECLSSMPAALRSSQIIALKLL 240

Query: 722  PSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGG 781
            P   S R  PPP        G+          Q++    PG   PP   G  G  G  G 
Sbjct: 241  PLLNSVRLAPPPVIKRRTFQGEQS--------QASIQGPPGPPGPPGPSGPLGHPGLPGP 292

Query: 782  GGAY----PPQPDFQPSQRTSASKLGALSL-GSFNKPSSKDNLFGQSCLAALSTACQNMI 836
             G      PP P   P  +    + G   + G   K  +K          A   A   M 
Sbjct: 293  MGPPGLPGPPGPKGDPGIQGYHGRKGERGMPGMPGKHGAK---------GAPGIAVAGMK 343

Query: 837  ASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGT 896
               G P        +  P     L Q    G A     G    PG   PG PGP GP G 
Sbjct: 344  GEPGIPGTKGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGRGEPG--PPGLPGPPGPKGE 401

Query: 897  SSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPG 956
            +    +  GPP  P        +     +   G+ G+P       G+G     +G+++  
Sbjct: 402  AGVDGQV-GPPGQPGDKGERGAAGEQGPDGPKGSKGEP-------GKGEMVDYNGNINEA 453

Query: 957  TFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAEL 1016
                +  A     G PG+ PGQ    GA       GE  G P P           KG   
Sbjct: 454  LQEIRTLALM---GPPGL-PGQIGPPGAPGIPGQKGEI-GLPGP-----PGHDGEKGPRG 503

Query: 1017 LLGDQ----PDLIGSLDG--GAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALV 1070
              GD     P      DG  G K ++  P       ++  T  A      S  +  +A  
Sbjct: 504  KPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQA-----GSPGEKGEAGE 558

Query: 1071 KASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTP 1130
            K   +P   G   +P     AG  G K      G          P + G  G PG PGTP
Sbjct: 559  KG--NPGAEGLQGVPGPKGEAGLDGAKGEKGFQGEKGDRGPLGLPGASGLDGRPGPPGTP 616

Query: 1131 GLEQVRTPTSSSG 1143
            G   V  P    G
Sbjct: 617  GPIGVPGPAGPKG 629



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 99/374 (26%), Positives = 124/374 (33%), Gaps = 36/374 (9%)

Query: 579 GHPGDVGQGGLVHGGPVGGLAQPNFER--EGGSTGAGR--LGTFEQQAPHLAQESAWFSG 634
           G PG  G+ G      + GL     E+   G S G GR   G      P   +  A   G
Sbjct: 347 GIPGTKGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGRGEPGPPGLPGPPGPKGEAGVDG 406

Query: 635 PHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPA 694
              PPG   P   G  G   + GP  P  +   P  G  V + G + E ++   E    A
Sbjct: 407 QVGPPGQ--PGDKGERGAAGEQGPDGPKGSKGEPGKGEMVDYNGNINEALQ---EIRTLA 461

Query: 695 LPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALG--GQPGFPFGAAG 752
           L  P        G  GQ+  PGA  G+P    E   P P       G  G+PG   G  G
Sbjct: 462 LMGPP-------GLPGQIGPPGAP-GIPGQKGEIGLPGPPGHDGEKGPRGKPG-DMGPPG 512

Query: 753 RQSTPHSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDF-QPSQRTSASKLG---ALSLG 808
               P   PG + PP   G  G  G  G  G          P ++  A + G   A  L 
Sbjct: 513 ----PQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPGEKGEAGEKGNPGAEGLQ 568

Query: 809 SFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGA 868
               P  +  L G            +    LG P  +    +  PP     +      G 
Sbjct: 569 GVPGPKGEAGLDGAKGEKGFQGEKGDR-GPLGLPGASGLDGRPGPPGTPGPIGVPGPAGP 627

Query: 869 AVAGNPGSDYFPGGTAP----GAPGPGGPSGTSSS-GSKASGPPNPPAQGDGTSLSPNYT 923
              G  GS   PG T P    G PG  GP G   + G +       P    G   +P   
Sbjct: 628 K--GERGSKGDPGMTGPTGAAGLPGLHGPPGDKGNRGERGKKGSRGPKGDKGDQGAPGLD 685

Query: 924 LESTSGNDGKPVSG 937
                G DG PV G
Sbjct: 686 APCPLGEDGLPVQG 699



 Score = 35.4 bits (80), Expect = 0.36
 Identities = 89/388 (22%), Positives = 122/388 (31%), Gaps = 61/388 (15%)

Query: 43  GPPGPV-DPAMSAL-GEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHG 100
           GPPGP  DP +    G     GM   P    A+G   +   G++ +P      G++   G
Sbjct: 300 GPPGPKGDPGIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEPGIPGTKGEKGAEG 359

Query: 101 HPGSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHMAESQ 160
            PG        P   G  G      + + GGR  G  G  G  G  PP  +G   +    
Sbjct: 360 SPGL-------PGLLGQKGEKGDAGNSIGGGR--GEPGPPGLPG--PPGPKGEAGVDGQV 408

Query: 161 GPESFGPQRPGNLPDFHSSGAS-------SHAVPAPCLPLDQSPN--------RAASFHG 205
           GP    P +PG+  +  ++G         S   P     +D + N        R  +  G
Sbjct: 409 GP----PGQPGDKGERGAAGEQGPDGPKGSKGEPGKGEMVDYNGNINEALQEIRTLALMG 464

Query: 206 LPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQL----PHYAA 261
            P   G       P     +G     E   PG  P GH     P    G +    P    
Sbjct: 465 PPGLPGQIGPPGAPGIPGQKG-----EIGLPG--PPGHDGEKGPRGKPGDMGPPGPQGPP 517

Query: 262 GRQVPGGA-----FPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFER 316
           G+  P G       PG+       G  G +    +  +   +     +  Q   G   E 
Sbjct: 518 GKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPGEKGEAGEKGNPGAEGLQGVPGPKGEA 577

Query: 317 FSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPP 376
                K   G +   G R PL  P            P  P    P   PG         P
Sbjct: 578 GLDGAKGEKGFQGEKGDRGPLGLPGASG----LDGRPGPPGTPGPIGVPG---------P 624

Query: 377 ALPRPQQGEAGTPSGGLQDGGPMLPSQH 404
           A P+ ++G  G P      G   LP  H
Sbjct: 625 AGPKGERGSKGDPGMTGPTGAAGLPGLH 652


>gi|22027565 alpha 1 type XIII collagen isoform 1 [Homo sapiens]
          Length = 717

 Score = 90.9 bits (224), Expect = 7e-18
 Identities = 137/503 (27%), Positives = 182/503 (36%), Gaps = 99/503 (19%)

Query: 681  QEPMRMPGEGHVPALPSPGLQFG-----GSLGGLGQLQSPG-AGVGLPSAASERRPPPPD 734
            + P   PG    PA   P  + G     G++G  G++ SPG AG+ +       R PP  
Sbjct: 109  EAPKTSPGCNCPPAFQGPTGRPGLPGDKGAIGMPGRVGSPGDAGLSIIGP----RGPPGQ 164

Query: 735  FATSALGGQPGFPFGAAGRQSTPHSGP----GVNSPPSAGGGGGSSGGGGGGGAYPPQPD 790
              T    G PG P G  G+    H GP    G+  PP   G  G  G  G  G YP +  
Sbjct: 165  PGTRGFPGFPG-PIGLDGKPG--HPGPKGDMGLTGPPGQPGPQGQKGEKGQCGEYPHR-- 219

Query: 791  FQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQN--MIASLGAPNLNVTF 848
                                             CL+++  A ++  +IA    P LN + 
Sbjct: 220  --------------------------------ECLSSMPAALRSSQIIALKLLPLLN-SV 246

Query: 849  NKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAP----GAPGPGGPSGTSSSGSKAS 904
                PP  KR+  Q E   A++ G PG    PG + P    G PGP GP G         
Sbjct: 247  RLAPPPVIKRRTFQGEQSQASIQGPPGPPGPPGPSGPLGHPGLPGPMGPPGLP------- 299

Query: 905  GPPNPPAQGDGTSLSPNYTLESTSGNDGKP----VSGGGGRGRGRRKRDSGHVSPGTFFD 960
            GPP P  +GD   +   +  +   G  G P      G  G      K + G   PGT  +
Sbjct: 300  GPPGP--KGD-PGIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEPG--IPGTKGE 354

Query: 961  KYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGD 1020
            K   A  S G PG+  GQ+   G A  G+S G  RG P P    L  P   KG   + G 
Sbjct: 355  K--GAEGSPGLPGLL-GQKGEKGDA--GNSIGGGRGEPGP--PGLPGPPGPKGEAGVDGQ 407

Query: 1021 -----QPDLIGSLDG-------GAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQA 1068
                 QP   G           G K     P  GE      + + A ++  + +   P  
Sbjct: 408  VGPPGQPGDKGERGAAGEQGPDGPKGSKGEPGKGEMVDYNGNINEALQEIRTLALMGPPG 467

Query: 1069 LVKASRSPLVTGSPK------LPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGG 1122
            L      P   G P       LP      GE GP+  P  +G              G  G
Sbjct: 468  LPGQIGPPGAPGIPGQKGEIGLPGPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKG 527

Query: 1123 GPGHPGTPGLEQVRTPTSSSGAP 1145
              GHPG+PG +  +  T  +G+P
Sbjct: 528  ENGHPGSPGEKGEKGETGQAGSP 550



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 148/563 (26%), Positives = 179/563 (31%), Gaps = 93/563 (16%)

Query: 632  FSGPHPPPGDLLPRRMGGSGLPADCG-PHDPSLA---PPPPPGGSGVL----FRGP--LQ 681
            F GP   PG  LP   G  G+P   G P D  L+   P  PPG  G      F GP  L 
Sbjct: 123  FQGPTGRPG--LPGDKGAIGMPGRVGSPGDAGLSIIGPRGPPGQPGTRGFPGFPGPIGLD 180

Query: 682  EPMRMPGEGHVPALPSPGLQFG--GSLGGLGQ---------LQSPGAGVG---------L 721
                 PG      L  P  Q G  G  G  GQ         L S  A +          L
Sbjct: 181  GKPGHPGPKGDMGLTGPPGQPGPQGQKGEKGQCGEYPHRECLSSMPAALRSSQIIALKLL 240

Query: 722  PSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGG 781
            P   S R  PPP        G+          Q++    PG   PP   G  G  G  G 
Sbjct: 241  PLLNSVRLAPPPVIKRRTFQGEQS--------QASIQGPPGPPGPPGPSGPLGHPGLPGP 292

Query: 782  GGAY----PPQPDFQPSQRTSASKLGALSL-GSFNKPSSKDNLFGQSCLAALSTACQNMI 836
             G      PP P   P  +    + G   + G   K  +K          A   A   M 
Sbjct: 293  MGPPGLPGPPGPKGDPGIQGYHGRKGERGMPGMPGKHGAK---------GAPGIAVAGMK 343

Query: 837  ASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGT 896
               G P        +  P     L Q    G A     G    PG   PG PGP GP G 
Sbjct: 344  GEPGIPGTKGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGRGEPG--PPGLPGPPGPKGE 401

Query: 897  SSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPG 956
            +    +  GPP  P        +     +   G+ G+P       G+G     +G+++  
Sbjct: 402  AGVDGQV-GPPGQPGDKGERGAAGEQGPDGPKGSKGEP-------GKGEMVDYNGNINEA 453

Query: 957  TFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAEL 1016
                +  A     G PG+ PGQ    GA       GE  G P P           KG   
Sbjct: 454  LQEIRTLALM---GPPGL-PGQIGPPGAPGIPGQKGEI-GLPGP-----PGHDGEKGPRG 503

Query: 1017 LLGDQ----PDLIGSLDG--GAKSDSSSPNVGEFASDEVSTSYAN---EDEVSSSSDNPQ 1067
              GD     P      DG  G K ++  P       ++  T  A    E   +    NP 
Sbjct: 504  KPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPGEKGEAGEKGNPG 563

Query: 1068 ALVKASRSPLVTGSPKLP-------PRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGG 1120
            A V     P   G P  P       P+G  AG  G K      G          P + G 
Sbjct: 564  AEVPGLPGP--EGPPGPPGLQGVPGPKGE-AGLDGAKGEKGFQGEKGDRGPLGLPGASGL 620

Query: 1121 GGGPGHPGTPGLEQVRTPTSSSG 1143
             G PG PGTPG   V  P    G
Sbjct: 621  DGRPGPPGTPGPIGVPGPAGPKG 643



 Score = 57.4 bits (137), Expect = 9e-08
 Identities = 129/530 (24%), Positives = 167/530 (31%), Gaps = 88/530 (16%)

Query: 492 PGLPGEFTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQR 551
           PG PG    P  D   +GPP Q P P       Q Q+ ++ Q  +   ++         R
Sbjct: 183 PGHPG----PKGDMGLTGPPGQ-PGP-------QGQKGEKGQCGEYPHRECLSSMPAALR 230

Query: 552 QNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTG 611
            +  + +K +   N  +    P + +    G+  Q  +   GP G    P     G S  
Sbjct: 231 SSQIIALKLLPLLNSVRLAPPPVIKRRTFQGEQSQASIQ--GPPGPPGPP-----GPSGP 283

Query: 612 AGRLGTFEQQAPHLAQESAWFSGPHPPPGDL----LPRRMGGSGLPADCGPHDPSLAPPP 667
            G  G      P          GP  P GD        R G  G+P   G H    AP  
Sbjct: 284 LGHPGLPGPMGP------PGLPGPPGPKGDPGIQGYHGRKGERGMPGMPGKHGAKGAP-- 335

Query: 668 PPGGSGVLFRGPLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASE 727
                G+   G   EP     +G   A  SPGL   G LG  G+    G  +G       
Sbjct: 336 -----GIAVAGMKGEPGIPGTKGEKGAEGSPGLP--GLLGQKGEKGDAGNSIG----GGR 384

Query: 728 RRPPPPDFATSALGGQPGFPFGAAG--RQSTPHSGPGVNSPPSAGGGGGSSGGGGGGG-- 783
             P PP      L G PG P G AG   Q  P   PG      A G  G  G  G  G  
Sbjct: 385 GEPGPP-----GLPGPPG-PKGEAGVDGQVGPPGQPGDKGERGAAGEQGPDGPKGSKGEP 438

Query: 784 AYPPQPDFQPSQRTSASKLGALSL-------GSFNKPSSKDNLFGQSCLAAL-------- 828
                 D+  +   +  ++  L+L       G    P +   + GQ     L        
Sbjct: 439 GKGEMVDYNGNINEALQEIRTLALMGPPGLPGQIGPPGAP-GIPGQKGEIGLPGPPGHDG 497

Query: 829 STACQNMIASLGAPNLNVTFNKKNPPEGK----------RKLSQNETDGAAVAGNPGS-- 876
               +     +G P       K  PP  K           K  + ET  A   G  G   
Sbjct: 498 EKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPGEKGEAG 557

Query: 877 -DYFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPV 935
               PG   PG PGP GP G         G P P  +            +   G+ G P+
Sbjct: 558 EKGNPGAEVPGLPGPEGPPGPPG----LQGVPGPKGEAGLDGAKGEKGFQGEKGDRG-PL 612

Query: 936 SGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGAA 985
              G  G   R    G  +PG       A P         PG    +GAA
Sbjct: 613 GLPGASGLDGRPGPPG--TPGPIGVPGPAGPKGERGSKGDPGMTGPTGAA 660



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 100/383 (26%), Positives = 125/383 (32%), Gaps = 40/383 (10%)

Query: 579 GHPGDVGQGGLVHGGPVGGLAQPNFER--EGGSTGAGR--LGTFEQQAPHLAQESAWFSG 634
           G PG  G+ G      + GL     E+   G S G GR   G      P   +  A   G
Sbjct: 347 GIPGTKGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGRGEPGPPGLPGPPGPKGEAGVDG 406

Query: 635 PHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPA 694
              PPG   P   G  G   + GP  P  +   P  G  V + G + E ++   E    A
Sbjct: 407 QVGPPGQ--PGDKGERGAAGEQGPDGPKGSKGEPGKGEMVDYNGNINEALQ---EIRTLA 461

Query: 695 LPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALG--GQPGFPFGAAG 752
           L  P        G  GQ+  PGA  G+P    E   P P       G  G+PG   G  G
Sbjct: 462 LMGPP-------GLPGQIGPPGAP-GIPGQKGEIGLPGPPGHDGEKGPRGKPG-DMGPPG 512

Query: 753 RQSTP-HSGP----GVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSL 807
            Q  P   GP    G N  P + G  G  G  G  G+   + +        A   G    
Sbjct: 513 PQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPGEKGEAGEKGNPGAEVPGLPGP 572

Query: 808 GSFNKPSSKDNLFGQSCLAALSTAC--------QNMIASLGAPNLNVTFNKKNPPEGKRK 859
                P     + G    A L  A         +     LG P  +    +  PP     
Sbjct: 573 EGPPGPPGLQGVPGPKGEAGLDGAKGEKGFQGEKGDRGPLGLPGASGLDGRPGPPGTPGP 632

Query: 860 LSQNETDGAAVAGNPGSDYFPGGTAP----GAPGPGGPSGTSSS-GSKASGPPNPPAQGD 914
           +      G    G  GS   PG T P    G PG  GP G   + G +       P    
Sbjct: 633 IGVPGPAGPK--GERGSKGDPGMTGPTGAAGLPGLHGPPGDKGNRGERGKKGSRGPKGDK 690

Query: 915 GTSLSPNYTLESTSGNDGKPVSG 937
           G   +P        G DG PV G
Sbjct: 691 GDQGAPGLDAPCPLGEDGLPVQG 713



 Score = 35.8 bits (81), Expect = 0.28
 Identities = 92/355 (25%), Positives = 121/355 (34%), Gaps = 45/355 (12%)

Query: 43  GPPGPVDPAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQP-VHGFFG--GQQPHH 99
           GPPGP  P+   LG P + G  M P G            G +  P + G+ G  G++   
Sbjct: 273 GPPGPPGPS-GPLGHPGLPGP-MGPPGLPG-------PPGPKGDPGIQGYHGRKGERGMP 323

Query: 100 GHPGSHHPHQHHPHFG--GNFGGPD-PGASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHM 156
           G PG H   +  P     G  G P  PG     G    G  G  G LG +    +    +
Sbjct: 324 GMPGKHGA-KGAPGIAVAGMKGEPGIPGTKGEKGAE--GSPGLPGLLGQKGEKGDAGNSI 380

Query: 157 AESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDSHS 216
              +G E   P  PG       +G      P P  P D+    AA   G     GS    
Sbjct: 381 GGGRG-EPGPPGLPGPPGPKGEAGVDGQVGP-PGQPGDKGERGAAGEQGPDGPKGSKGEP 438

Query: 217 LEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQL-PHYAAGRQVPGGAFPGASA 275
            +   V   G ++         A  G      P    GQ+ P  A G  +PG    G   
Sbjct: 439 GKGEMVDYNGNINEALQEIRTLALMG------PPGLPGQIGPPGAPG--IPGQK--GEIG 488

Query: 276 MPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERF---SGARKMPVGLEPSVG 332
           +P   G  G      +P    P   Q P  +    GV  E     S   K   G     G
Sbjct: 489 LPGPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAG 548

Query: 333 SRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQGEAG 387
           S     +  ++  P  +   P  P  + PP PPGL          +P P +GEAG
Sbjct: 549 SPGEKGEAGEKGNPGAEV--PGLPGPEGPPGPPGL--------QGVPGP-KGEAG 592


>gi|22027587 alpha 1 type XIII collagen isoform 8 [Homo sapiens]
          Length = 705

 Score = 90.9 bits (224), Expect = 7e-18
 Identities = 137/503 (27%), Positives = 182/503 (36%), Gaps = 99/503 (19%)

Query: 681  QEPMRMPGEGHVPALPSPGLQFG-----GSLGGLGQLQSPG-AGVGLPSAASERRPPPPD 734
            + P   PG    PA   P  + G     G++G  G++ SPG AG+ +       R PP  
Sbjct: 109  EAPKTSPGCNCPPAFQGPTGRPGLPGDKGAIGMPGRVGSPGDAGLSIIGP----RGPPGQ 164

Query: 735  FATSALGGQPGFPFGAAGRQSTPHSGP----GVNSPPSAGGGGGSSGGGGGGGAYPPQPD 790
              T    G PG P G  G+    H GP    G+  PP   G  G  G  G  G YP +  
Sbjct: 165  PGTRGFPGFPG-PIGLDGKPG--HPGPKGDMGLTGPPGQPGPQGQKGEKGQCGEYPHR-- 219

Query: 791  FQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQN--MIASLGAPNLNVTF 848
                                             CL+++  A ++  +IA    P LN + 
Sbjct: 220  --------------------------------ECLSSMPAALRSSQIIALKLLPLLN-SV 246

Query: 849  NKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAP----GAPGPGGPSGTSSSGSKAS 904
                PP  KR+  Q E   A++ G PG    PG + P    G PGP GP G         
Sbjct: 247  RLAPPPVIKRRTFQGEQSQASIQGPPGPPGPPGPSGPLGHPGLPGPMGPPGLP------- 299

Query: 905  GPPNPPAQGDGTSLSPNYTLESTSGNDGKP----VSGGGGRGRGRRKRDSGHVSPGTFFD 960
            GPP P  +GD   +   +  +   G  G P      G  G      K + G   PGT  +
Sbjct: 300  GPPGP--KGD-PGIQGYHGRKGERGMPGMPGKHGAKGAPGIAVAGMKGEPG--IPGTKGE 354

Query: 961  KYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGD 1020
            K   A  S G PG+  GQ+   G A  G+S G  RG P P    L  P   KG   + G 
Sbjct: 355  K--GAEGSPGLPGLL-GQKGEKGDA--GNSIGGGRGEPGP--PGLPGPPGPKGEAGVDGQ 407

Query: 1021 -----QPDLIGSLDG-------GAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQA 1068
                 QP   G           G K     P  GE      + + A ++  + +   P  
Sbjct: 408  VGPPGQPGDKGERGAAGEQGPDGPKGSKGEPGKGEMVDYNGNINEALQEIRTLALMGPPG 467

Query: 1069 LVKASRSPLVTGSPK------LPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGG 1122
            L      P   G P       LP      GE GP+  P  +G              G  G
Sbjct: 468  LPGQIGPPGAPGIPGQKGEIGLPGPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKG 527

Query: 1123 GPGHPGTPGLEQVRTPTSSSGAP 1145
              GHPG+PG +  +  T  +G+P
Sbjct: 528  ENGHPGSPGEKGEKGETGQAGSP 550



 Score = 58.5 bits (140), Expect = 4e-08
 Identities = 148/576 (25%), Positives = 182/576 (31%), Gaps = 109/576 (18%)

Query: 632  FSGPHPPPGDLLPRRMGGSGLPADCG-PHDPSLA---PPPPPGGSGVL----FRGP--LQ 681
            F GP   PG  LP   G  G+P   G P D  L+   P  PPG  G      F GP  L 
Sbjct: 123  FQGPTGRPG--LPGDKGAIGMPGRVGSPGDAGLSIIGPRGPPGQPGTRGFPGFPGPIGLD 180

Query: 682  EPMRMPGEGHVPALPSPGLQFG--GSLGGLGQ---------LQSPGAGVG---------L 721
                 PG      L  P  Q G  G  G  GQ         L S  A +          L
Sbjct: 181  GKPGHPGPKGDMGLTGPPGQPGPQGQKGEKGQCGEYPHRECLSSMPAALRSSQIIALKLL 240

Query: 722  PSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGG 781
            P   S R  PPP        G+          Q++    PG   PP   G  G  G  G 
Sbjct: 241  PLLNSVRLAPPPVIKRRTFQGEQS--------QASIQGPPGPPGPPGPSGPLGHPGLPGP 292

Query: 782  GGAY----PPQPDFQPSQRTSASKLGALSL-GSFNKPSSKDNLFGQSCLAALSTACQNMI 836
             G      PP P   P  +    + G   + G   K  +K          A   A   M 
Sbjct: 293  MGPPGLPGPPGPKGDPGIQGYHGRKGERGMPGMPGKHGAK---------GAPGIAVAGMK 343

Query: 837  ASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGT 896
               G P        +  P     L Q    G A     G    PG   PG PGP GP G 
Sbjct: 344  GEPGIPGTKGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGRGEPG--PPGLPGPPGPKGE 401

Query: 897  SSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPG 956
            +    +  GPP  P        +     +   G+ G+P       G+G     +G+++  
Sbjct: 402  AGVDGQV-GPPGQPGDKGERGAAGEQGPDGPKGSKGEP-------GKGEMVDYNGNINEA 453

Query: 957  TFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAEL 1016
                +  A     G PG+ PGQ    GA       GE  G P P           KG   
Sbjct: 454  LQEIRTLALM---GPPGL-PGQIGPPGAPGIPGQKGEI-GLPGP-----PGHDGEKGPRG 503

Query: 1017 LLGDQ----PDLIGSLDG--GAKSDSSSPNVGEFASDEVSTSYAN---EDEVSSSSDNPQ 1067
              GD     P      DG  G K ++  P       ++  T  A    E   +    NP 
Sbjct: 504  KPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPGEKGEAGEKGNPG 563

Query: 1068 ALVKASRSPLVTGSPKLP-------PRGVGA-----------GEHGPKAPPPALGLGIMS 1109
            A V     P   G P  P       P+G              GE G + P   LGL    
Sbjct: 564  AEVPGLPGP--EGPPGPPGLQGVPGPKGEAGLDGAKGEKGFQGEKGDRGP---LGLPGTP 618

Query: 1110 NSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAP 1145
                 P   G  G  G  G PG+     PT ++G P
Sbjct: 619  GPIGVPGPAGPKGERGSKGDPGM---TGPTGAAGLP 651



 Score = 54.7 bits (130), Expect = 6e-07
 Identities = 136/557 (24%), Positives = 178/557 (31%), Gaps = 105/557 (18%)

Query: 492 PGLPGEFTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQR 551
           PG PG    P  D   +GPP Q P P       Q Q+ ++ Q  +   ++         R
Sbjct: 183 PGHPG----PKGDMGLTGPPGQ-PGP-------QGQKGEKGQCGEYPHRECLSSMPAALR 230

Query: 552 QNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTG 611
            +  + +K +   N  +    P + +    G+  Q  +   GP G    P     G S  
Sbjct: 231 SSQIIALKLLPLLNSVRLAPPPVIKRRTFQGEQSQASIQ--GPPGPPGPP-----GPSGP 283

Query: 612 AGRLGTFEQQAPHLAQESAWFSGPHPPPGDL----LPRRMGGSGLPADCGPHDPSLAPPP 667
            G  G      P          GP  P GD        R G  G+P   G H    AP  
Sbjct: 284 LGHPGLPGPMGP------PGLPGPPGPKGDPGIQGYHGRKGERGMPGMPGKHGAKGAP-- 335

Query: 668 PPGGSGVLFRGPLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASE 727
                G+   G   EP     +G   A  SPGL   G LG  G+    G  +G       
Sbjct: 336 -----GIAVAGMKGEPGIPGTKGEKGAEGSPGLP--GLLGQKGEKGDAGNSIG----GGR 384

Query: 728 RRPPPPDFATSALGGQPGFPFGAAG--RQSTPHSGPGVNSPPSAGGGGGSSGGGGGGG-- 783
             P PP      L G PG P G AG   Q  P   PG      A G  G  G  G  G  
Sbjct: 385 GEPGPP-----GLPGPPG-PKGEAGVDGQVGPPGQPGDKGERGAAGEQGPDGPKGSKGEP 438

Query: 784 AYPPQPDFQPSQRTSASKLGALSL-------GSFNKPSSKDNLFGQSCLAAL-------- 828
                 D+  +   +  ++  L+L       G    P +   + GQ     L        
Sbjct: 439 GKGEMVDYNGNINEALQEIRTLALMGPPGLPGQIGPPGAP-GIPGQKGEIGLPGPPGHDG 497

Query: 829 STACQNMIASLGAPNLNVTFNKKNPPEGK----------RKLSQNETDGAAVAGNPGS-- 876
               +     +G P       K  PP  K           K  + ET  A   G  G   
Sbjct: 498 EKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPGEKGEAG 557

Query: 877 -DYFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPAQG--DGTSLSPNYT---------- 923
               PG   PG PGP GP G         G P P  +   DG      +           
Sbjct: 558 EKGNPGAEVPGLPGPEGPPGPPG----LQGVPGPKGEAGLDGAKGEKGFQGEKGDRGPLG 613

Query: 924 LESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPG--VSPGQQQA 981
           L  T G  G P    G +G    K D G   P       +  P   G PG   + G++  
Sbjct: 614 LPGTPGPIGVP-GPAGPKGERGSKGDPGMTGP----TGAAGLPGLHGPPGDKGNRGERGK 668

Query: 982 SGAAVGGSSAGETRGAP 998
            G+       G+ +GAP
Sbjct: 669 KGSRGPKGDKGD-QGAP 684



 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 101/381 (26%), Positives = 126/381 (33%), Gaps = 48/381 (12%)

Query: 579 GHPGDVGQGGLVHGGPVGGLAQPNFER--EGGSTGAGR--LGTFEQQAPHLAQESAWFSG 634
           G PG  G+ G      + GL     E+   G S G GR   G      P   +  A   G
Sbjct: 347 GIPGTKGEKGAEGSPGLPGLLGQKGEKGDAGNSIGGGRGEPGPPGLPGPPGPKGEAGVDG 406

Query: 635 PHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPA 694
              PPG   P   G  G   + GP  P  +   P  G  V + G + E ++   E    A
Sbjct: 407 QVGPPGQ--PGDKGERGAAGEQGPDGPKGSKGEPGKGEMVDYNGNINEALQ---EIRTLA 461

Query: 695 LPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALG--GQPGFPFGAAG 752
           L  P        G  GQ+  PGA  G+P    E   P P       G  G+PG   G  G
Sbjct: 462 LMGPP-------GLPGQIGPPGAP-GIPGQKGEIGLPGPPGHDGEKGPRGKPG-DMGPPG 512

Query: 753 RQSTPHSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDF-QPSQRTSASKLGALSLGSFN 811
               P   PG + PP   G  G  G  G  G          P ++  A + G       N
Sbjct: 513 ----PQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAGSPGEKGEAGEKG-------N 561

Query: 812 KPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKN--PPEGKR-KLSQNETDG- 867
             +    L G           Q +    G   L+    +K     +G R  L    T G 
Sbjct: 562 PGAEVPGLPGPEGPPG-PPGLQGVPGPKGEAGLDGAKGEKGFQGEKGDRGPLGLPGTPGP 620

Query: 868 ------AAVAGNPGSDYFPGGTAP----GAPGPGGPSGTSSS-GSKASGPPNPPAQGDGT 916
                 A   G  GS   PG T P    G PG  GP G   + G +       P    G 
Sbjct: 621 IGVPGPAGPKGERGSKGDPGMTGPTGAAGLPGLHGPPGDKGNRGERGKKGSRGPKGDKGD 680

Query: 917 SLSPNYTLESTSGNDGKPVSG 937
             +P        G DG PV G
Sbjct: 681 QGAPGLDAPCPLGEDGLPVQG 701



 Score = 35.8 bits (81), Expect = 0.28
 Identities = 92/355 (25%), Positives = 121/355 (34%), Gaps = 45/355 (12%)

Query: 43  GPPGPVDPAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQP-VHGFFG--GQQPHH 99
           GPPGP  P+   LG P + G  M P G            G +  P + G+ G  G++   
Sbjct: 273 GPPGPPGPS-GPLGHPGLPGP-MGPPGLPG-------PPGPKGDPGIQGYHGRKGERGMP 323

Query: 100 GHPGSHHPHQHHPHFG--GNFGGPD-PGASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHM 156
           G PG H   +  P     G  G P  PG     G    G  G  G LG +    +    +
Sbjct: 324 GMPGKHGA-KGAPGIAVAGMKGEPGIPGTKGEKGAE--GSPGLPGLLGQKGEKGDAGNSI 380

Query: 157 AESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDSHS 216
              +G E   P  PG       +G      P P  P D+    AA   G     GS    
Sbjct: 381 GGGRG-EPGPPGLPGPPGPKGEAGVDGQVGP-PGQPGDKGERGAAGEQGPDGPKGSKGEP 438

Query: 217 LEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQL-PHYAAGRQVPGGAFPGASA 275
            +   V   G ++         A  G      P    GQ+ P  A G  +PG    G   
Sbjct: 439 GKGEMVDYNGNINEALQEIRTLALMG------PPGLPGQIGPPGAPG--IPGQK--GEIG 488

Query: 276 MPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERF---SGARKMPVGLEPSVG 332
           +P   G  G      +P    P   Q P  +    GV  E     S   K   G     G
Sbjct: 489 LPGPPGHDGEKGPRGKPGDMGPPGPQGPPGKDGPPGVKGENGHPGSPGEKGEKGETGQAG 548

Query: 333 SRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQGEAG 387
           S     +  ++  P  +   P  P  + PP PPGL          +P P +GEAG
Sbjct: 549 SPGEKGEAGEKGNPGAEV--PGLPGPEGPPGPPGL--------QGVPGP-KGEAG 592


>gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]
          Length = 1073

 Score = 90.5 bits (223), Expect = 1e-17
 Identities = 168/637 (26%), Positives = 208/637 (32%), Gaps = 123/637 (19%)

Query: 579  GHPGDVGQGGL--------VHG-----GPVGGLAQPNFEREGGSTGA-------GRLGTF 618
            G PG+ G+ GL        V G     G  G L  P  + + G  G        G  GT 
Sbjct: 277  GRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTT 336

Query: 619  EQQAPHLAQESAWFSGPHPPPGDL-LPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFR 677
                PH         GP    GD  LP   G  G P + GP  P+     PPG  G    
Sbjct: 337  SLFTPHPRMPGE--QGPKGEKGDPGLPGEPGLQGRPGELGPQGPT----GPPGAKGQEGA 390

Query: 678  GPLQEPMRMPGE-GHVPALPSPGLQFGGSLGGLGQLQSPGAGV--GLPSAASERRPPPPD 734
                     PG  GHV A P P     GS+G  G   +PG     G   AA E   P P 
Sbjct: 391  HGAPGAAGNPGAPGHVGA-PGPSGP-PGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGP- 447

Query: 735  FATSALGGQPGFPFGAAGRQSTPHSG----PGVNSP---------PSAGGGGGSSGGGGG 781
                   G PG P G  G+      G    PG+  P         P   G  GS G  G 
Sbjct: 448  VGPRGDPGAPGLP-GPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGI 506

Query: 782  GGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGA 841
            G A PP P   P  + S    G         P+ +D L      + LS    N++A    
Sbjct: 507  GVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLS-----SLLSPGDINLLAK--- 558

Query: 842  PNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPG--GTA--PGAPGPGGPSGTS 897
               +V  +    P G   L   + D   V G PG +   G  G A  PG PGP G +G  
Sbjct: 559  ---DVCNDCPPGPPGLPGLPGFKGD-KGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQ 614

Query: 898  SS----------GSKAS-------------GPPNPPAQGDGTSLSPNYTLESTSGNDGKP 934
             S          G K               G P PP        +    ++ + G +G P
Sbjct: 615  GSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPP 674

Query: 935  VSGG-----GGRGR-GRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGG 988
               G     G  G  G+  RD     PG         P   G PG+ PG + A G     
Sbjct: 675  GPQGPSGLPGIPGEEGKEGRDGKPGPPGE--------PGKAGEPGL-PGPEGARGPPGFK 725

Query: 989  SSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDE 1048
               G++ GAP P          G+   + L  Q  L G      K   + P   +     
Sbjct: 726  GHTGDS-GAPGPR---------GESGAMGLPGQEGLPG------KDGDTGPTGPQGPQGP 769

Query: 1049 VSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIM 1108
                  N    S     P        S    GSP LP      G  GP+ PP   G   +
Sbjct: 770  RGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLP------GFLGPRGPPGEPGEKGV 823

Query: 1109 SNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAP 1145
                  P   G  G  G  G PG++  + P    G P
Sbjct: 824  PGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQP 860



 Score = 80.5 bits (197), Expect = 1e-14
 Identities = 164/612 (26%), Positives = 195/612 (31%), Gaps = 155/612 (25%)

Query: 573  PNLAQL-GHPGDVGQGGLVHG----GPVG--GLA-QPNFEREGGSTGAGRLGTFEQQAPH 624
            P L QL G PG+ G+ GL       G +G  GLA +P  + E G  GA          P 
Sbjct: 243  PGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGF-------PG 295

Query: 625  LAQESAWFSGPHPPPGDL-LPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEP 683
            +  E     G     G+L LP   G  G   + GP      PP  PG + +    P    
Sbjct: 296  VRGEK----GDQGEKGELGLPGLKGDRGEKGEAGP----AGPPGLPGTTSLFTPHPRMPG 347

Query: 684  MRMP-GEGHVPALPS-PGLQFG-GSLGGLGQLQSPGA-----GVGLPSAASERRPPPPDF 735
             + P GE   P LP  PGLQ   G LG  G    PGA       G P AA          
Sbjct: 348  EQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAA---------- 397

Query: 736  ATSALGGQPGFP--FGAAGRQSTPHS--GPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDF 791
                  G PG P   GA G    P S   PG+   P   G  G  G  G  G+  P P  
Sbjct: 398  ------GNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGS--PGPVG 449

Query: 792  QPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKK 851
                  +    G    G   +P  +                       G+P L      K
Sbjct: 450  PRGDPGAPGLPGPPGKGKDGEPGLR-----------------------GSPGLPGPLGTK 486

Query: 852  NPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGP----P 907
                        +     + G+PGS   PG    G PGP GP G   S      P    P
Sbjct: 487  G-----------DRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGP 535

Query: 908  NPPAQGDGTS--LSPN--YTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYS 963
              PA  DG S  LSP     L     ND  P   G                PG   DK  
Sbjct: 536  QGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPG------------LPGFKGDK-- 581

Query: 964  AAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPD 1023
                  G PG  PG++   G        GE      P    +  P   +G     G+   
Sbjct: 582  ------GVPG-KPGREGTEG------KKGEAGPPGLPGPPGIAGPQGSQGERGADGEV-- 626

Query: 1024 LIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSP- 1082
                   G K D   P V  F     +      D ++           A+  P + GSP 
Sbjct: 627  -------GQKGDQGHPGVPGFMGPPGNPGPPGADGIAG----------AAGPPGIQGSPG 669

Query: 1083 -KLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTP--- 1138
             + PP     G  GP   P   G          P   G  G  G PG PG E  R P   
Sbjct: 670  KEGPP-----GPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGF 724

Query: 1139 ---TSSSGAPPP 1147
               T  SGAP P
Sbjct: 725  KGHTGDSGAPGP 736



 Score = 74.3 bits (181), Expect = 7e-13
 Identities = 156/624 (25%), Positives = 194/624 (31%), Gaps = 95/624 (15%)

Query: 579  GHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTG-------AGRLGTFEQQAPHLAQESAW 631
            G PG VG  G    GP G +  P      G  G       AG  G+     P     +  
Sbjct: 401  GAPGHVGAPG--PSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPG 458

Query: 632  FSGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAP-----PPPPGGSGVLFRGPLQEPMRM 686
              GP     D  P   G  GLP   G      AP     P   G  G+   GP   P   
Sbjct: 459  LPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGP-PGPSGP 517

Query: 687  PGEGHVPA---LPS-PGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALGG 742
            PG+   P    LP  PG Q      GL  L SPG    L        PP P      L G
Sbjct: 518  PGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPP----GLPG 573

Query: 743  QPGFPF-----GAAGRQSTPHSG-----PGVNSPPSAGGGGGSSGGGGGGG--------A 784
             PGF       G  GR+ T         PG+  PP   G  GS G  G  G         
Sbjct: 574  LPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQG 633

Query: 785  YPPQPDFQ--------PSQRTSASKLGALSL-GSFNK--------PSSKDNLFGQSCLAA 827
            +P  P F         P     A   G   + GS  K        PS    + G+     
Sbjct: 634  HPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEG 693

Query: 828  LS--TACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDG----AAVAGNPGSDYFPG 881
                          G P L      + PP  K     +   G    +   G PG +  PG
Sbjct: 694  RDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPG 753

Query: 882  GTAPGAP-GPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGG-- 938
                  P GP GP G      K +G P  P +  G S +P    + + G +G P   G  
Sbjct: 754  KDGDTGPTGPQGPQGPRGPPGK-NGSPGSPGE-PGPSGTPGQ--KGSKGENGSPGLPGFL 809

Query: 939  GGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVS-----PGQQQASGAAVGGSSAGE 993
            G RG      + G   PG         P   G PG       PG +   G   G    G+
Sbjct: 810  GPRGPPGEPGEKG--VPGK-----EGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGD 862

Query: 994  TRGAPTPHEKALTSPSWGKGAELLLGD-----QPDLIGSLDGGAKSDSSSPNVGEFASDE 1048
                       L  P    G    +G      QP   G        ++    + E    +
Sbjct: 863  PGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQ 922

Query: 1049 VSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIM 1108
            + T  A        +  P A +K+S+     G P  P +    G  GP   P   G G +
Sbjct: 923  LETRLAY-----LLAQMPPAYMKSSQGR--PGPPGPPGKDGLPGRAGPMGEPGRPGQGGL 975

Query: 1109 SNSTSTPDSYGGGGGPGHPGTPGL 1132
               +      G  G  G PG PG+
Sbjct: 976  EGPSGPIGPKGERGAKGDPGAPGV 999



 Score = 67.8 bits (164), Expect = 7e-11
 Identities = 104/401 (25%), Positives = 134/401 (33%), Gaps = 82/401 (20%)

Query: 579  GHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGA-------GRLGTFEQQAPHLAQESAW 631
            G PG  G+ GL   GP G    P F+   G +GA       G +G   Q+          
Sbjct: 702  GEPGKAGEPGLP--GPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTG 759

Query: 632  FSGPHPPPGDLLPRRMGGS-GLPADCGPHDP-----SLAPPPPPGGSGVLF-RGPLQEPM 684
             +GP  P G   P    GS G P + GP        S      PG  G L  RGP  EP 
Sbjct: 760  PTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPG 819

Query: 685  R--MPGEGHVPALPS-PGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALG 741
               +PG+  VP  P  PG +      G+   + P  G G P                   
Sbjct: 820  EKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQP------------------- 860

Query: 742  GQPGFPFGAAGRQST--PHSGPGVNSPPSAGGGGGSSGGGGGGGAYPP--------QPDF 791
            G PG P G  G      P   PG N P    G  G  G  G  G  P         Q + 
Sbjct: 861  GDPGIP-GHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEEL 919

Query: 792  QPSQRTSASKLGALSLGSFNK----------PSSKDNLFGQSCLAALSTACQNMIASLGA 841
                 T  + L A    ++ K          P  KD L G++            +   G 
Sbjct: 920  GKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRA----------GPMGEPGR 969

Query: 842  PNLNVTFNKKNP--PEGKRKLS----------QNETDGAAVAGNPGSDYFPGGTAPGAPG 889
            P          P  P+G+R             + E     + G PG   +     PG PG
Sbjct: 970  PGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPG 1029

Query: 890  PGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGN 930
            P G +G +       GPP PP Q D +  +   +L +  GN
Sbjct: 1030 PQGETGPAGHPG-LPGPPGPPGQCDPSQCAYFASLAARPGN 1069



 Score = 58.5 bits (140), Expect = 4e-08
 Identities = 164/704 (23%), Positives = 228/704 (32%), Gaps = 149/704 (21%)

Query: 43   GPPGPV----DPAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFG--GQQ 96
            G PGPV    DP    L  PP  G + EP              GL+  P  G  G  G +
Sbjct: 443  GSPGPVGPRGDPGAPGLPGPPGKGKDGEP--------------GLRGSP--GLPGPLGTK 486

Query: 97   PHHGHPGSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHM 156
               G PG        P   G+ G  DPG         +G  G  G  G  PP  +G    
Sbjct: 487  GDRGAPGI-------PGSPGSRG--DPG---------IGVAGPPGPSG--PPGDKG---S 523

Query: 157  AESQGPESF-GPQRPGN---LPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGS 212
              S+G   F GPQ P     L    S G  +      C   +  P       GLP   G 
Sbjct: 524  PGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVC---NDCPPGPPGLPGLPGFKGD 580

Query: 213  DSHSLEPRRVTNQGAVDSLEYNYPG-EAPSGHFDMFSPSDSEGQ---------------- 255
                 +P R   +G     E   PG   P G   +  P  S+G+                
Sbjct: 581  KGVPGKPGREGTEGKKG--EAGPPGLPGPPG---IAGPQGSQGERGADGEVGQKGDQGHP 635

Query: 256  -LPHYAAGRQVPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFF 314
             +P +      PG   PGA  +  AAG  G+      P ++ P   Q P       G   
Sbjct: 636  GVPGFMGPPGNPGP--PGADGIAGAAGPPGIQ---GSPGKEGPPGPQGPSGLPGIPGEEG 690

Query: 315  ERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQ----------PPQQPPQQQPPPP 364
            +     +  P G     G   P +  P+ A  PP  +          P  +      P  
Sbjct: 691  KEGRDGKPGPPGEPGKAGE--PGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQ 748

Query: 365  PGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSE 424
             GL  +     P  P+  QG  G P    ++G P  P +      P  +           
Sbjct: 749  EGLPGKDGDTGPTGPQGPQGPRGPPG---KNGSPGSPGEPGPSGTPGQKGSKGENGSPGL 805

Query: 425  PVFSMQHPPPQQAPNQRL---QHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGA 481
            P F     PP +   + +   +     P     K  R D PG  G        G   +  
Sbjct: 806  PGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGD-PGIKGDKGPPGGKGQPGDPG 864

Query: 482  LDNH------LSPSAYPGLPGEFTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQ 535
            +  H      + P   PG  G   PP P   P  P L+  +P  ++L++  Q++  +Q +
Sbjct: 865  IPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLE 924

Query: 536  QQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPV 595
             +                 A ++ QM     +    +P     G PG  G+ GL   G  
Sbjct: 925  TR----------------LAYLLAQMPPAYMKSSQGRP-----GPPGPPGKDGL--PGRA 961

Query: 596  GGLAQPNFEREGGSTG-AGRLGTFEQQAPHLAQESAWFSGPHPPPGDLLPRRMGGSGLPA 654
            G + +P    +GG  G +G +G   ++            G    PG  L   MG  G+P 
Sbjct: 962  GPMGEPGRPGQGGLEGPSGPIGPKGERGA---------KGDPGAPGVGLRGEMGPPGIPG 1012

Query: 655  DCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPALPSP 698
               P +P  A    PG  G         P    G    P LP P
Sbjct: 1013 Q--PGEPGYAKDGLPGIPG---------PQGETGPAGHPGLPGP 1045



 Score = 50.8 bits (120), Expect = 8e-06
 Identities = 133/550 (24%), Positives = 178/550 (32%), Gaps = 83/550 (15%)

Query: 626  AQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPPP------PGGSGVLF--- 676
            ++ES    GP   P + + +   G+     CG  + S+ P         P G+G  F   
Sbjct: 164  SRESLDLLGPRTDPWENVDQGAQGA-----CGRGNTSVLPSSVAPQCSMPKGTGHEFSAA 218

Query: 677  ---RGPLQEPMRMPGEGHVPALPSPGL-QFGGSLGGLGQLQSPGAGVGLPSAASER--RP 730
               +GP  +         + A  +PGL Q  G  G  G+   PG   GL     E+    
Sbjct: 219  LGTQGPADQRADARASCILAAKTAPGLKQLNGEPGERGEDGLPGKP-GLRGEIGEQGLAG 277

Query: 731  PPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPPSAGGGG--GSSGGGGGGGAYPPQ 788
             P +   + L G PGFP G  G +        +  P   G  G  G +G  G  G     
Sbjct: 278  RPGEKGEAGLPGAPGFP-GVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTT 336

Query: 789  PDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTF 848
              F P  R    +      G    P                   Q     LG        
Sbjct: 337  SLFTPHPRMPGEQGPKGEKGDPGLPGEP--------------GLQGRPGELGPQG----- 377

Query: 849  NKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGPPN 908
                PP  K +   +   GAA  GNPG+   PG    GAPGP GP G+  +      P  
Sbjct: 378  -PTGPPGAKGQEGAHGAPGAA--GNPGA---PGHV--GAPGPSGPPGSVGAPGLRGTPGK 429

Query: 909  PPAQGD----GTSLSPNYTLESTSGNDGKPVSGG--GGRGRGRRKRDSGHVSPGTFFDKY 962
               +G+    G   SP        G  G P + G  G  G+G+        SPG      
Sbjct: 430  DGERGEKGAAGEEGSPGPV-----GPRGDPGAPGLPGPPGKGKDGEPGLRGSPG--LPGP 482

Query: 963  SAAPDSGGAPGV--SPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGD 1020
                   GAPG+  SPG +   G  V G         P P     + P   KG+    G 
Sbjct: 483  LGTKGDRGAPGIPGSPGSRGDPGIGVAGP--------PGP-----SGPPGDKGSPGSRG- 528

Query: 1021 QPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTG 1080
             P   G   G A  D  S  +     + ++    N+              K  +   V G
Sbjct: 529  LPGFPGP-QGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKG--VPG 585

Query: 1081 SPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTS 1140
             P         GE GP   P   G+     S     + G  G  G  G PG+     P  
Sbjct: 586  KPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPG 645

Query: 1141 SSGAPPPDEI 1150
            + G P  D I
Sbjct: 646  NPGPPGADGI 655



 Score = 37.0 bits (84), Expect = 0.13
 Identities = 72/272 (26%), Positives = 91/272 (33%), Gaps = 52/272 (19%)

Query: 135 GYGGAAGGLGSQPPFAE-GYEHMAESQGPES-FGPQRPGNLPDFHSSGASSHAVPAPCLP 192
           G+ G  G  G Q    E G   +   +G +   GP  P  LP     G +S   P P +P
Sbjct: 292 GFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLP-----GTTSLFTPHPRMP 346

Query: 193 LDQSPNRAASFHGLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDS 252
            +Q P       GLP   G                        PGE          P   
Sbjct: 347 GEQGPKGEKGDPGLPGEPGLQGR--------------------PGE--------LGPQGP 378

Query: 253 EGQLPHYAAGRQVPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGV 312
            G  P  A G++   GA PGA+  P A G VG     A  P   P     P  +    G 
Sbjct: 379 TG--PPGAKGQEGAHGA-PGAAGNPGAPGHVG-----APGPSGPPGSVGAPGLR----GT 426

Query: 313 FFERFSGARKMPVGLEPSVGSRHPLMQPPQQA-PPPPQQQPPQQPPQQQPPPPPGLL-VR 370
             +      K   G E S G   P   P     P PP +    +P  +  P  PG L  +
Sbjct: 427 PGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTK 486

Query: 371 QNSCPPALPRPQQGEAGTPSGGLQDGGPMLPS 402
            +   P +P    G  G P  G+   GP  PS
Sbjct: 487 GDRGAPGIP-GSPGSRGDP--GIGVAGPPGPS 515



 Score = 36.6 bits (83), Expect = 0.16
 Identities = 81/347 (23%), Positives = 114/347 (32%), Gaps = 26/347 (7%)

Query: 862  QNETDGAAVA-GNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSP 920
            +N   GA  A G   +   P   AP    P G     S+     GP +  A    + +  
Sbjct: 179  ENVDQGAQGACGRGNTSVLPSSVAPQCSMPKGTGHEFSAALGTQGPADQRADARASCILA 238

Query: 921  NYTLESTSGNDGKPVSGG--GGRGRGRRKRDSGHVS-PGTFFDKYSAA-PDSGGAPGV-- 974
              T       +G+P   G  G  G+   + + G     G   +K  A  P + G PGV  
Sbjct: 239  AKTAPGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRG 298

Query: 975  SPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSLDGGAKS 1034
              G Q   G  +G       RG     E     P    G   L    P + G  + G K 
Sbjct: 299  EKGDQGEKGE-LGLPGLKGDRGEKG--EAGPAGPPGLPGTTSLFTPHPRMPG--EQGPKG 353

Query: 1035 DSSSPNV-GEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGE 1093
            +   P + GE            +          Q    A  +P   G+P  P      G 
Sbjct: 354  EKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQE--GAHGAPGAAGNPGAPGH---VGA 408

Query: 1094 HGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPPDEIHPL 1153
             GP  PP ++G   +  +       G  G  G  G+PG    R    + G P P    P 
Sbjct: 409  PGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGP----PG 464

Query: 1154 EILQAQIQLQRQQFSISEDQPLGLKGGKKGECAVGASGAQNGDSELG 1200
            +    +  L+    S     PLG K G +G   +  S    GD  +G
Sbjct: 465  KGKDGEPGLRG---SPGLPGPLGTK-GDRGAPGIPGSPGSRGDPGIG 507


>gi|55750053 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 89.0 bits (219), Expect = 3e-17
 Identities = 150/556 (26%), Positives = 190/556 (34%), Gaps = 95/556 (17%)

Query: 57  EPPILGMNMEPYGFHARGHSELHAGG----LQAQPVHGFFGGQQPHHGHP--GSHHPHQH 110
           EPP   M   P G     H +L+ GG    L   P+    GG     G P  G  HP   
Sbjct: 199 EPPTSRMFQAPPGAPPP-HPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPT 257

Query: 111 HPHF--------------------GGNFGGPDPGASCLH---------GGRLLGYGGAAG 141
            P                      GGN     P A+  H           R L    A+ 
Sbjct: 258 TPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASP 317

Query: 142 -GLGSQP-PFAEGYEH-MAESQGPESFGPQR-PGNLPDFHSSGASSHAVPAPCLPLDQSP 197
            GLG+QP P      H M +  G    GP++ P   P  HS   +S + PAP +    S 
Sbjct: 318 PGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSS 377

Query: 198 NRAASFHGLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYP-------GEAPSGHFDMFSPS 250
           + ++S     SSS S S S  P   +   A+ S  +++P          P  +     PS
Sbjct: 378 SSSSSA-AASSSSSSSSSSASPFPASQ--ALPSYPHSFPPPTSLSVSNQPPKYTQPSLPS 434

Query: 251 D---SEGQLPHYAAGRQV------PGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQ 301
               S+G  P    GR +      PG   P   A   A   V     H Q  QQQ QQQQ
Sbjct: 435 QAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQ 494

Query: 302 QPQQQQQQH---------GVF---FERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQ 349
           Q QQQQQQH         G F    E  S     P  + PS+GS  P    P   PPP  
Sbjct: 495 QQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHS 554

Query: 350 QQPPQQPPQQQPPPPPGL----LVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPSQHA 405
           Q    Q     PP            Q S P + P P QG  G P        P +P+   
Sbjct: 555 QVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPF-----PPVPTVTT 609

Query: 406 QFEYPIHRLENRSMHPYSEPVFSMQHPPP--QQAPNQRLQHFDAPPYMNVAKRPRFDF-- 461
                   +   +  P      S   PPP  ++AP+        PP       P F    
Sbjct: 610 SSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGT 669

Query: 462 -PGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSFPSGPPLQHPAPDHQ 520
            PG  G    A   G+   G      SP+  PG      P  P   PS PP         
Sbjct: 670 PPGYRGTSPPAG-PGTFKPG------SPTVGPG---PLPPAGPSGLPSLPPPPAAPASGP 719

Query: 521 SLQQQQQQQQQQQQQQ 536
            L   Q +Q+  ++ +
Sbjct: 720 PLSATQIKQEPAEEYE 735



 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 163/672 (24%), Positives = 220/672 (32%), Gaps = 137/672 (20%)

Query: 154 EHMAESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRA-ASFHGLPSSSGS 212
           E+ ++S    S GP RP + P            P+P  P D +P +  ASF   PS + +
Sbjct: 142 ENDSDSSSGLSQGPARPYHPPPLFP--------PSP-QPPDSTPRQPEASFEPHPSVTPT 192

Query: 213 DSHS-LEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAAGRQVPGGAFP 271
             H+ +EP          S  +  P  AP  H  ++ P  + G L     G +       
Sbjct: 193 GYHAPMEPPT--------SRMFQAPPGAPPPHPQLY-PGGTGGVLSGPPMGPK------- 236

Query: 272 GASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSV 331
           G  A     G  G  K H  PP   P              V     SGA        P  
Sbjct: 237 GGGAASSVGGPNG-GKQH--PPPTTPIS------------VSSSGASGAPPTKPPTTPVG 281

Query: 332 GSRHPLMQPPQQAP------PPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQ--- 382
           G   P   PP   P      PPP   P  +P       PPGL  +    P  LP P    
Sbjct: 282 GGNLPSAPPPANFPHVTPNLPPP---PALRPLNNASASPPGLGAQP--LPGHLPSPHAMG 336

Query: 383 QGEAGTPSGGLQDGGPMLPSQHA-------------QFEYPIHRLENRSMHPYSEPVFSM 429
           QG  G P G  + G  + PS H+             +F Y      + +    S    S 
Sbjct: 337 QGMGGLPPGP-EKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSS 395

Query: 430 QHP-PPQQAPNQRLQHFDAPPYMNVAKRP-RFDFPGSAGVDRCASWNGSMHNGALDNHLS 487
             P P  QA       F  P  ++V+ +P ++  P    +   A W+           L 
Sbjct: 396 ASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPS---LPSQAVWSQGPPPPPPYGRLL 452

Query: 488 PSAYPGLPGEFTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQ 547
            ++    PG F P       + PP+      HQ  QQQQQQQQQQQQQQQQ         
Sbjct: 453 ANSNAH-PGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPP 511

Query: 548 QQQRQNAALMIKQMASRNQQQRLRQPNLAQL-------GH-PGDVGQGGLVHGGPVGGLA 599
                +    ++  +S +       P+L  L        H P    Q      GP G   
Sbjct: 512 PGAFPHP---LEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNG--- 565

Query: 600 QPNFEREGGSTGAGRLGTFEQQAPHLAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPH 659
            P       S+ +   G++    P  +Q       P PP   +       S + A     
Sbjct: 566 -PPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASS 624

Query: 660 DPSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGV 719
                   PP        GP     R P  G       PG +             PG+  
Sbjct: 625 PAGYKTASPP--------GPPPYGKRAPSPGAYKTATPPGYK-------------PGS-- 661

Query: 720 GLPSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSP--PSAGGGGGSSG 777
                       PP F T   G  PG+      R ++P +GPG   P  P+ G G     
Sbjct: 662 ------------PPSFRT---GTPPGY------RGTSPPAGPGTFKPGSPTVGPGPLPPA 700

Query: 778 GGGGGGAYPPQP 789
           G  G  + PP P
Sbjct: 701 GPSGLPSLPPPP 712



 Score = 64.7 bits (156), Expect = 6e-10
 Identities = 132/565 (23%), Positives = 185/565 (32%), Gaps = 84/565 (14%)

Query: 635  PHPPPGDLLPRRMGGSGLP----ADCGPHDPSLAP-----------PPP-----PGGSGV 674
            P P P D  PR+   S  P       G H P   P           PPP     PGG+G 
Sbjct: 167  PSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGG 226

Query: 675  LFRGPLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPPPD 734
            +  GP   PM   G G   ++       GG  GG  Q   P   + + S+ +   PP   
Sbjct: 227  VLSGP---PMGPKGGGAASSV-------GGPNGGK-QHPPPTTPISVSSSGASGAPPTKP 275

Query: 735  FATSALGGQ-PGFPFGAAGRQSTPH---------------SGPGVNSPPSAGGGGGSSGG 778
              T   GG  P  P  A     TP+               S PG+ + P  G        
Sbjct: 276  PTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAM 335

Query: 779  GGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKP-------SSKDNLFGQSCLAALSTA 831
            G G G  PP P+  P+   S   L   S  +   P       SS  +    S  ++ S++
Sbjct: 336  GQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSS 395

Query: 832  CQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPG 891
                 AS   P+   +F    PP     +S N+         P    +  G     P P 
Sbjct: 396  ASPFPASQALPSYPHSF----PPPTSLSVS-NQPPKYTQPSLPSQAVWSQG-----PPPP 445

Query: 892  GPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKR--- 948
             P G   + S A   P PP+ G  ++  P  +         +       + + ++++   
Sbjct: 446  PPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHG 505

Query: 949  DSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSP 1008
            +SG   PG F        + G +    P     S  ++     G     P PH +   S 
Sbjct: 506  NSGPPPPGAF----PHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAH-LPPPHSQVSYSQ 560

Query: 1009 SWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQA 1068
            +   G  +          S  G       SP+ G   +             S++     A
Sbjct: 561  AGPNGPPVSSSSNSSSSTS-QGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIA 619

Query: 1069 LVKASRSPLVTGSPKLPP----RGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGP 1124
             V +S +   T SP  PP    R    G +    PP        S  T TP  Y G   P
Sbjct: 620  TVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPP 679

Query: 1125 GHPGT--PGLEQVRTPTSSSGAPPP 1147
              PGT  PG     +PT   G  PP
Sbjct: 680  AGPGTFKPG-----SPTVGPGPLPP 699



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 91/330 (27%), Positives = 118/330 (35%), Gaps = 60/330 (18%)

Query: 874  PGSDYFPGGTA---PGAP-GPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSG 929
            P    +PGGT     G P GP G    SS G    G  +PP     T +S      S+SG
Sbjct: 215  PHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPT---TPISV-----SSSG 266

Query: 930  NDGKPVS-------GGGGRGRGRRKRDSGHVSPGTF-------FDKYSAAPDSGGA---P 972
              G P +       GGG         +  HV+P           +  SA+P   GA   P
Sbjct: 267  ASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLP 326

Query: 973  GVSPGQQQASGAAVGGSSAGETRG---APTPHEKALTSPSWGKGAELLLGDQPDLIGSLD 1029
            G  P    A G  +GG   G  +G   AP+PH     S S      +          S  
Sbjct: 327  GHLPSPH-AMGQGMGGLPPGPEKGPTLAPSPHSLPPASSS-APAPPMRFPYSSSSSSSAA 384

Query: 1030 GGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGV 1089
              + S SSS +   F + +   SY +       S  P   +  S  P     P LP + V
Sbjct: 385  ASSSSSSSSSSASPFPASQALPSYPH-------SFPPPTSLSVSNQPPKYTQPSLPSQAV 437

Query: 1090 GAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPPDE 1149
             +   GP  PPP   L  ++NS + P       GP  P T           S+  PP   
Sbjct: 438  WS--QGPPPPPPYGRL--LANSNAHP-------GPFPPSTGA--------QSTAHPPVST 478

Query: 1150 IHPLEILQAQIQLQRQQFSISEDQPLGLKG 1179
             H     Q Q Q Q+QQ    + Q  G  G
Sbjct: 479  HHHHHQQQQQQQQQQQQQQQQQQQHHGNSG 508



 Score = 39.3 bits (90), Expect = 0.025
 Identities = 81/315 (25%), Positives = 101/315 (32%), Gaps = 40/315 (12%)

Query: 623 PHLAQESAWFSGPHPPP--GDLLPRRMGGSG-LPADCGPHDPSLAPPP---------PPG 670
           P L  ++ W  GP PPP  G LL       G  P   G    S A PP            
Sbjct: 430 PSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQ--STAHPPVSTHHHHHQQQQ 487

Query: 671 GSGVLFRGPLQEPMRMPGEGHVP---ALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASE 727
                 +   Q+  +  G    P   A P P L+ G S        SP  G   P     
Sbjct: 488 QQQQQQQQQQQQQQQHHGNSGPPPPGAFPHP-LEGGSSHHAHPYAMSPSLGSLRPYPPGP 546

Query: 728 RRPPPPDFATS-ALGGQPGFPFGAAGRQSTPHS-GPGVNSPPSAGGGGGSSGGGGGGGAY 785
              PPP    S +  G  G P  ++   S+  S G    S PS      S G  G    +
Sbjct: 547 AHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSP-----SQGPQGAPYPF 601

Query: 786 PPQPDFQPSQRTSASKLGALSLGSFN-KPSSKDNLFGQSCLAALSTACQNMIASLGAPNL 844
           PP P    S  T ++ +  ++      K +S          A    A +        P  
Sbjct: 602 PPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGS 661

Query: 845 NVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKAS 904
             +F    PP G R  S     G    G+P          PG   P GPSG  S      
Sbjct: 662 PPSFRTGTPP-GYRGTSPPAGPGTFKPGSPT-------VGPGPLPPAGPSGLPSL----- 708

Query: 905 GPPNPPAQGDGTSLS 919
            PP P A   G  LS
Sbjct: 709 -PPPPAAPASGPPLS 722



 Score = 37.4 bits (85), Expect = 0.096
 Identities = 70/293 (23%), Positives = 94/293 (32%), Gaps = 53/293 (18%)

Query: 888  PGPGGPSGTSSSGSKA---SGPPNP-PAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGR 943
            P P  PS   S   ++    G  +P     D  S SP+     +  ND    S G  +G 
Sbjct: 97   PRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDS-SSGLSQGP 155

Query: 944  GRRKRDSGHVSPGTFFDKYSAAPDSGGA---------PGVSPGQQQASGAAVGGSSAGET 994
             R         P   F      PDS            P V+P    A             
Sbjct: 156  ARPYH------PPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAP 209

Query: 995  RGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYA 1054
             GAP PH +     + G     +L   P  +G   GGA S    PN G+      +    
Sbjct: 210  PGAPPPHPQLYPGGTGG-----VLSGPP--MGPKGGGAASSVGGPNGGKQHPPPTTPI-- 260

Query: 1055 NEDEVSSSSDNPQALVKASRSPLVTGS--------------PKLPPRGVGAGEHGPKAPP 1100
                VSSS  +     K   +P+  G+              P LPP       +   A P
Sbjct: 261  ---SVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASP 317

Query: 1101 PALGLGIMSNSTSTPDSYGGGGGPGHPG-------TPGLEQVRTPTSSSGAPP 1146
            P LG   +     +P + G G G   PG        P    +   +SS+ APP
Sbjct: 318  PGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPP 370



 Score = 33.5 bits (75), Expect = 1.4
 Identities = 41/160 (25%), Positives = 56/160 (35%), Gaps = 22/160 (13%)

Query: 1015 ELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYA--NEDEVSSSSDNPQALVKA 1072
            EL     P  + SLDG + +D  S +  +   D  STS +  +   V + SD+   L + 
Sbjct: 95   ELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQG 154

Query: 1073 SR-----SPLVTGSPKLP--------------PRGVGAGEHGPKAPPPALGLGIMSNSTS 1113
                    PL   SP+ P              P     G H P  PP +        +  
Sbjct: 155  PARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPP 214

Query: 1114 T-PDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPPDEIHP 1152
              P  Y GG G    G P   +     SS G P   + HP
Sbjct: 215  PHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHP 254


>gi|55750041 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 89.0 bits (219), Expect = 3e-17
 Identities = 150/556 (26%), Positives = 190/556 (34%), Gaps = 95/556 (17%)

Query: 57  EPPILGMNMEPYGFHARGHSELHAGG----LQAQPVHGFFGGQQPHHGHP--GSHHPHQH 110
           EPP   M   P G     H +L+ GG    L   P+    GG     G P  G  HP   
Sbjct: 199 EPPTSRMFQAPPGAPPP-HPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPT 257

Query: 111 HPHF--------------------GGNFGGPDPGASCLH---------GGRLLGYGGAAG 141
            P                      GGN     P A+  H           R L    A+ 
Sbjct: 258 TPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASP 317

Query: 142 -GLGSQP-PFAEGYEH-MAESQGPESFGPQR-PGNLPDFHSSGASSHAVPAPCLPLDQSP 197
            GLG+QP P      H M +  G    GP++ P   P  HS   +S + PAP +    S 
Sbjct: 318 PGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSS 377

Query: 198 NRAASFHGLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYP-------GEAPSGHFDMFSPS 250
           + ++S     SSS S S S  P   +   A+ S  +++P          P  +     PS
Sbjct: 378 SSSSSA-AASSSSSSSSSSASPFPASQ--ALPSYPHSFPPPTSLSVSNQPPKYTQPSLPS 434

Query: 251 D---SEGQLPHYAAGRQV------PGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQ 301
               S+G  P    GR +      PG   P   A   A   V     H Q  QQQ QQQQ
Sbjct: 435 QAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQ 494

Query: 302 QPQQQQQQH---------GVF---FERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQ 349
           Q QQQQQQH         G F    E  S     P  + PS+GS  P    P   PPP  
Sbjct: 495 QQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHS 554

Query: 350 QQPPQQPPQQQPPPPPGL----LVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPSQHA 405
           Q    Q     PP            Q S P + P P QG  G P        P +P+   
Sbjct: 555 QVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPF-----PPVPTVTT 609

Query: 406 QFEYPIHRLENRSMHPYSEPVFSMQHPPP--QQAPNQRLQHFDAPPYMNVAKRPRFDF-- 461
                   +   +  P      S   PPP  ++AP+        PP       P F    
Sbjct: 610 SSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGT 669

Query: 462 -PGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSFPSGPPLQHPAPDHQ 520
            PG  G    A   G+   G      SP+  PG      P  P   PS PP         
Sbjct: 670 PPGYRGTSPPAG-PGTFKPG------SPTVGPG---PLPPAGPSGLPSLPPPPAAPASGP 719

Query: 521 SLQQQQQQQQQQQQQQ 536
            L   Q +Q+  ++ +
Sbjct: 720 PLSATQIKQEPAEEYE 735



 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 163/672 (24%), Positives = 220/672 (32%), Gaps = 137/672 (20%)

Query: 154 EHMAESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRA-ASFHGLPSSSGS 212
           E+ ++S    S GP RP + P            P+P  P D +P +  ASF   PS + +
Sbjct: 142 ENDSDSSSGLSQGPARPYHPPPLFP--------PSP-QPPDSTPRQPEASFEPHPSVTPT 192

Query: 213 DSHS-LEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAAGRQVPGGAFP 271
             H+ +EP          S  +  P  AP  H  ++ P  + G L     G +       
Sbjct: 193 GYHAPMEPPT--------SRMFQAPPGAPPPHPQLY-PGGTGGVLSGPPMGPK------- 236

Query: 272 GASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSV 331
           G  A     G  G  K H  PP   P              V     SGA        P  
Sbjct: 237 GGGAASSVGGPNG-GKQH--PPPTTPIS------------VSSSGASGAPPTKPPTTPVG 281

Query: 332 GSRHPLMQPPQQAP------PPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQ--- 382
           G   P   PP   P      PPP   P  +P       PPGL  +    P  LP P    
Sbjct: 282 GGNLPSAPPPANFPHVTPNLPPP---PALRPLNNASASPPGLGAQP--LPGHLPSPHAMG 336

Query: 383 QGEAGTPSGGLQDGGPMLPSQHA-------------QFEYPIHRLENRSMHPYSEPVFSM 429
           QG  G P G  + G  + PS H+             +F Y      + +    S    S 
Sbjct: 337 QGMGGLPPGP-EKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSS 395

Query: 430 QHP-PPQQAPNQRLQHFDAPPYMNVAKRP-RFDFPGSAGVDRCASWNGSMHNGALDNHLS 487
             P P  QA       F  P  ++V+ +P ++  P    +   A W+           L 
Sbjct: 396 ASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPS---LPSQAVWSQGPPPPPPYGRLL 452

Query: 488 PSAYPGLPGEFTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQ 547
            ++    PG F P       + PP+      HQ  QQQQQQQQQQQQQQQQ         
Sbjct: 453 ANSNAH-PGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPP 511

Query: 548 QQQRQNAALMIKQMASRNQQQRLRQPNLAQL-------GH-PGDVGQGGLVHGGPVGGLA 599
                +    ++  +S +       P+L  L        H P    Q      GP G   
Sbjct: 512 PGAFPHP---LEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNG--- 565

Query: 600 QPNFEREGGSTGAGRLGTFEQQAPHLAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPH 659
            P       S+ +   G++    P  +Q       P PP   +       S + A     
Sbjct: 566 -PPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASS 624

Query: 660 DPSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGV 719
                   PP        GP     R P  G       PG +             PG+  
Sbjct: 625 PAGYKTASPP--------GPPPYGKRAPSPGAYKTATPPGYK-------------PGS-- 661

Query: 720 GLPSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSP--PSAGGGGGSSG 777
                       PP F T   G  PG+      R ++P +GPG   P  P+ G G     
Sbjct: 662 ------------PPSFRT---GTPPGY------RGTSPPAGPGTFKPGSPTVGPGPLPPA 700

Query: 778 GGGGGGAYPPQP 789
           G  G  + PP P
Sbjct: 701 GPSGLPSLPPPP 712



 Score = 64.7 bits (156), Expect = 6e-10
 Identities = 132/565 (23%), Positives = 185/565 (32%), Gaps = 84/565 (14%)

Query: 635  PHPPPGDLLPRRMGGSGLP----ADCGPHDPSLAP-----------PPP-----PGGSGV 674
            P P P D  PR+   S  P       G H P   P           PPP     PGG+G 
Sbjct: 167  PSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGG 226

Query: 675  LFRGPLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPPPD 734
            +  GP   PM   G G   ++       GG  GG  Q   P   + + S+ +   PP   
Sbjct: 227  VLSGP---PMGPKGGGAASSV-------GGPNGGK-QHPPPTTPISVSSSGASGAPPTKP 275

Query: 735  FATSALGGQ-PGFPFGAAGRQSTPH---------------SGPGVNSPPSAGGGGGSSGG 778
              T   GG  P  P  A     TP+               S PG+ + P  G        
Sbjct: 276  PTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAM 335

Query: 779  GGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKP-------SSKDNLFGQSCLAALSTA 831
            G G G  PP P+  P+   S   L   S  +   P       SS  +    S  ++ S++
Sbjct: 336  GQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSS 395

Query: 832  CQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPG 891
                 AS   P+   +F    PP     +S N+         P    +  G     P P 
Sbjct: 396  ASPFPASQALPSYPHSF----PPPTSLSVS-NQPPKYTQPSLPSQAVWSQG-----PPPP 445

Query: 892  GPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKR--- 948
             P G   + S A   P PP+ G  ++  P  +         +       + + ++++   
Sbjct: 446  PPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHG 505

Query: 949  DSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSP 1008
            +SG   PG F        + G +    P     S  ++     G     P PH +   S 
Sbjct: 506  NSGPPPPGAF----PHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAH-LPPPHSQVSYSQ 560

Query: 1009 SWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQA 1068
            +   G  +          S  G       SP+ G   +             S++     A
Sbjct: 561  AGPNGPPVSSSSNSSSSTS-QGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIA 619

Query: 1069 LVKASRSPLVTGSPKLPP----RGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGP 1124
             V +S +   T SP  PP    R    G +    PP        S  T TP  Y G   P
Sbjct: 620  TVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPP 679

Query: 1125 GHPGT--PGLEQVRTPTSSSGAPPP 1147
              PGT  PG     +PT   G  PP
Sbjct: 680  AGPGTFKPG-----SPTVGPGPLPP 699



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 91/330 (27%), Positives = 118/330 (35%), Gaps = 60/330 (18%)

Query: 874  PGSDYFPGGTA---PGAP-GPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSG 929
            P    +PGGT     G P GP G    SS G    G  +PP     T +S      S+SG
Sbjct: 215  PHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPT---TPISV-----SSSG 266

Query: 930  NDGKPVS-------GGGGRGRGRRKRDSGHVSPGTF-------FDKYSAAPDSGGA---P 972
              G P +       GGG         +  HV+P           +  SA+P   GA   P
Sbjct: 267  ASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLP 326

Query: 973  GVSPGQQQASGAAVGGSSAGETRG---APTPHEKALTSPSWGKGAELLLGDQPDLIGSLD 1029
            G  P    A G  +GG   G  +G   AP+PH     S S      +          S  
Sbjct: 327  GHLPSPH-AMGQGMGGLPPGPEKGPTLAPSPHSLPPASSS-APAPPMRFPYSSSSSSSAA 384

Query: 1030 GGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGV 1089
              + S SSS +   F + +   SY +       S  P   +  S  P     P LP + V
Sbjct: 385  ASSSSSSSSSSASPFPASQALPSYPH-------SFPPPTSLSVSNQPPKYTQPSLPSQAV 437

Query: 1090 GAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPPDE 1149
             +   GP  PPP   L  ++NS + P       GP  P T           S+  PP   
Sbjct: 438  WS--QGPPPPPPYGRL--LANSNAHP-------GPFPPSTGA--------QSTAHPPVST 478

Query: 1150 IHPLEILQAQIQLQRQQFSISEDQPLGLKG 1179
             H     Q Q Q Q+QQ    + Q  G  G
Sbjct: 479  HHHHHQQQQQQQQQQQQQQQQQQQHHGNSG 508



 Score = 39.3 bits (90), Expect = 0.025
 Identities = 81/315 (25%), Positives = 101/315 (32%), Gaps = 40/315 (12%)

Query: 623 PHLAQESAWFSGPHPPP--GDLLPRRMGGSG-LPADCGPHDPSLAPPP---------PPG 670
           P L  ++ W  GP PPP  G LL       G  P   G    S A PP            
Sbjct: 430 PSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQ--STAHPPVSTHHHHHQQQQ 487

Query: 671 GSGVLFRGPLQEPMRMPGEGHVP---ALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASE 727
                 +   Q+  +  G    P   A P P L+ G S        SP  G   P     
Sbjct: 488 QQQQQQQQQQQQQQQHHGNSGPPPPGAFPHP-LEGGSSHHAHPYAMSPSLGSLRPYPPGP 546

Query: 728 RRPPPPDFATS-ALGGQPGFPFGAAGRQSTPHS-GPGVNSPPSAGGGGGSSGGGGGGGAY 785
              PPP    S +  G  G P  ++   S+  S G    S PS      S G  G    +
Sbjct: 547 AHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSP-----SQGPQGAPYPF 601

Query: 786 PPQPDFQPSQRTSASKLGALSLGSFN-KPSSKDNLFGQSCLAALSTACQNMIASLGAPNL 844
           PP P    S  T ++ +  ++      K +S          A    A +        P  
Sbjct: 602 PPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGS 661

Query: 845 NVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKAS 904
             +F    PP G R  S     G    G+P          PG   P GPSG  S      
Sbjct: 662 PPSFRTGTPP-GYRGTSPPAGPGTFKPGSPT-------VGPGPLPPAGPSGLPSL----- 708

Query: 905 GPPNPPAQGDGTSLS 919
            PP P A   G  LS
Sbjct: 709 -PPPPAAPASGPPLS 722



 Score = 37.4 bits (85), Expect = 0.096
 Identities = 70/293 (23%), Positives = 94/293 (32%), Gaps = 53/293 (18%)

Query: 888  PGPGGPSGTSSSGSKA---SGPPNP-PAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGR 943
            P P  PS   S   ++    G  +P     D  S SP+     +  ND    S G  +G 
Sbjct: 97   PRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDS-SSGLSQGP 155

Query: 944  GRRKRDSGHVSPGTFFDKYSAAPDSGGA---------PGVSPGQQQASGAAVGGSSAGET 994
             R         P   F      PDS            P V+P    A             
Sbjct: 156  ARPYH------PPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAP 209

Query: 995  RGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYA 1054
             GAP PH +     + G     +L   P  +G   GGA S    PN G+      +    
Sbjct: 210  PGAPPPHPQLYPGGTGG-----VLSGPP--MGPKGGGAASSVGGPNGGKQHPPPTTPI-- 260

Query: 1055 NEDEVSSSSDNPQALVKASRSPLVTGS--------------PKLPPRGVGAGEHGPKAPP 1100
                VSSS  +     K   +P+  G+              P LPP       +   A P
Sbjct: 261  ---SVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASP 317

Query: 1101 PALGLGIMSNSTSTPDSYGGGGGPGHPG-------TPGLEQVRTPTSSSGAPP 1146
            P LG   +     +P + G G G   PG        P    +   +SS+ APP
Sbjct: 318  PGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPP 370



 Score = 33.5 bits (75), Expect = 1.4
 Identities = 41/160 (25%), Positives = 56/160 (35%), Gaps = 22/160 (13%)

Query: 1015 ELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYA--NEDEVSSSSDNPQALVKA 1072
            EL     P  + SLDG + +D  S +  +   D  STS +  +   V + SD+   L + 
Sbjct: 95   ELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQG 154

Query: 1073 SR-----SPLVTGSPKLP--------------PRGVGAGEHGPKAPPPALGLGIMSNSTS 1113
                    PL   SP+ P              P     G H P  PP +        +  
Sbjct: 155  PARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPP 214

Query: 1114 T-PDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPPDEIHP 1152
              P  Y GG G    G P   +     SS G P   + HP
Sbjct: 215  PHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHP 254


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.132    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 77,989,673
Number of Sequences: 37866
Number of extensions: 5722684
Number of successful extensions: 108916
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1023
Number of HSP's successfully gapped in prelim test: 1813
Number of HSP's that attempted gapping in prelim test: 34220
Number of HSP's gapped (non-prelim): 34931
length of query: 1320
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1206
effective length of database: 13,930,794
effective search space: 16800537564
effective search space used: 16800537564
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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