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Search of human proteins with 55749442
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|55749442 transcription elongation factor A (SII)-like 4
[Homo sapiens]
(215 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|55749459 transcription elongation factor A (SII)-like 4 [Homo... 444 e-125
gi|55749442 transcription elongation factor A (SII)-like 4 [Homo... 444 e-125
gi|65505873 transcription elongation factor A (SII)-like 4 [Homo... 444 e-125
gi|55749451 transcription elongation factor A (SII)-like 4 [Homo... 444 e-125
gi|17933774 transcription elongation factor A (SII)-like 2 [Homo... 355 2e-98
gi|61175239 transcription elongation factor A (SII)-like 5 [Homo... 184 4e-47
gi|55749431 transcription elongation factor A (SII)-like 3 [Homo... 182 2e-46
gi|14249718 transcription elongation factor A (SII)-like 3 [Homo... 182 2e-46
gi|118600971 transcription elongation factor A (SII)-like 6 [Hom... 157 5e-39
gi|55743140 WW domain binding protein 5 [Homo sapiens] 63 2e-10
gi|55743147 WW domain binding protein 5 [Homo sapiens] 63 2e-10
gi|10047100 WW domain binding protein 5 [Homo sapiens] 63 2e-10
gi|55743145 WW domain binding protein 5 [Homo sapiens] 63 2e-10
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 60 1e-09
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 59 4e-09
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 53 2e-07
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 52 3e-07
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 52 3e-07
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 51 8e-07
gi|21361639 DIPB protein [Homo sapiens] 50 1e-06
gi|11225260 DNA topoisomerase I [Homo sapiens] 50 2e-06
gi|69354671 ATP-binding cassette, sub-family F, member 1 isoform... 50 2e-06
gi|13540523 nucleosomal binding protein 1 [Homo sapiens] 49 3e-06
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 49 3e-06
gi|157738619 smoothelin-like 1 [Homo sapiens] 49 4e-06
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 48 7e-06
gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens] 47 9e-06
gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens] 47 9e-06
gi|4557509 cylicin 2 [Homo sapiens] 47 9e-06
gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens] 47 1e-05
>gi|55749459 transcription elongation factor A (SII)-like 4 [Homo
sapiens]
Length = 215
Score = 444 bits (1141), Expect = e-125
Identities = 215/215 (100%), Positives = 215/215 (100%)
Query: 1 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK 60
MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK
Sbjct: 1 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK 60
Query: 61 DKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAED 120
DKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAED
Sbjct: 61 DKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAED 120
Query: 121 DVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFL 180
DVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFL
Sbjct: 121 DVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFL 180
Query: 181 WMQRNLQDPFYPRGPREFRGGCRAPRRDIEDIPYV 215
WMQRNLQDPFYPRGPREFRGGCRAPRRDIEDIPYV
Sbjct: 181 WMQRNLQDPFYPRGPREFRGGCRAPRRDIEDIPYV 215
>gi|55749442 transcription elongation factor A (SII)-like 4 [Homo
sapiens]
Length = 215
Score = 444 bits (1141), Expect = e-125
Identities = 215/215 (100%), Positives = 215/215 (100%)
Query: 1 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK 60
MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK
Sbjct: 1 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK 60
Query: 61 DKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAED 120
DKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAED
Sbjct: 61 DKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAED 120
Query: 121 DVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFL 180
DVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFL
Sbjct: 121 DVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFL 180
Query: 181 WMQRNLQDPFYPRGPREFRGGCRAPRRDIEDIPYV 215
WMQRNLQDPFYPRGPREFRGGCRAPRRDIEDIPYV
Sbjct: 181 WMQRNLQDPFYPRGPREFRGGCRAPRRDIEDIPYV 215
>gi|65505873 transcription elongation factor A (SII)-like 4 [Homo
sapiens]
Length = 215
Score = 444 bits (1141), Expect = e-125
Identities = 215/215 (100%), Positives = 215/215 (100%)
Query: 1 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK 60
MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK
Sbjct: 1 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK 60
Query: 61 DKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAED 120
DKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAED
Sbjct: 61 DKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAED 120
Query: 121 DVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFL 180
DVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFL
Sbjct: 121 DVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFL 180
Query: 181 WMQRNLQDPFYPRGPREFRGGCRAPRRDIEDIPYV 215
WMQRNLQDPFYPRGPREFRGGCRAPRRDIEDIPYV
Sbjct: 181 WMQRNLQDPFYPRGPREFRGGCRAPRRDIEDIPYV 215
>gi|55749451 transcription elongation factor A (SII)-like 4 [Homo
sapiens]
Length = 215
Score = 444 bits (1141), Expect = e-125
Identities = 215/215 (100%), Positives = 215/215 (100%)
Query: 1 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK 60
MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK
Sbjct: 1 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK 60
Query: 61 DKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAED 120
DKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAED
Sbjct: 61 DKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAED 120
Query: 121 DVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFL 180
DVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFL
Sbjct: 121 DVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFL 180
Query: 181 WMQRNLQDPFYPRGPREFRGGCRAPRRDIEDIPYV 215
WMQRNLQDPFYPRGPREFRGGCRAPRRDIEDIPYV
Sbjct: 181 WMQRNLQDPFYPRGPREFRGGCRAPRRDIEDIPYV 215
>gi|17933774 transcription elongation factor A (SII)-like 2 [Homo
sapiens]
Length = 227
Score = 355 bits (911), Expect = 2e-98
Identities = 179/228 (78%), Positives = 195/228 (85%), Gaps = 14/228 (6%)
Query: 1 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK 60
MEKL++ENEGM SNQGK++NEEQP E KPEV C LEDKKLENEG TEN GK EE LK
Sbjct: 1 MEKLFNENEGMPSNQGKIDNEEQPPHEGKPEVACILEDKKLENEGNTENTGKRV-EEPLK 59
Query: 61 DKGKPESEGEAK-EGKSEREGESEMEGGSEREGKPEIEGK------------PESEGEPG 107
DK KPES G+AK EGKSER+G+SEM+GGS+ EGKPE G+ PESEGEP
Sbjct: 60 DKEKPESAGKAKGEGKSERKGKSEMQGGSKTEGKPERGGRAEGEGEPDSEREPESEGEPE 119
Query: 108 SETRAAGKRPAEDDVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQD 167
SETRAAGKRPAEDD+PRKAKRKTNKGLA YLK+YKEAIHDMNFSNEDMIREFDNMA+V+D
Sbjct: 120 SETRAAGKRPAEDDIPRKAKRKTNKGLAQYLKQYKEAIHDMNFSNEDMIREFDNMARVED 179
Query: 168 EKRKSKQKLGAFLWMQRNLQDPFYPRGPREFRGGCRAPRRDIEDIPYV 215
++RKSKQKLGAFLWMQRNLQDPFYPRGPREFRGGCRAPRRD EDIPYV
Sbjct: 180 KRRKSKQKLGAFLWMQRNLQDPFYPRGPREFRGGCRAPRRDTEDIPYV 227
>gi|61175239 transcription elongation factor A (SII)-like 5 [Homo
sapiens]
Length = 206
Score = 184 bits (468), Expect = 4e-47
Identities = 100/217 (46%), Positives = 143/217 (65%), Gaps = 13/217 (5%)
Query: 1 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK 60
MEKLY ENEG N+ +E+E +P+DE E ++ K + E K + +GKT E +
Sbjct: 1 MEKLYKENEGKPENERNLESEGKPEDEGSTE-----DEGKSDEEEKPDMEGKTECEGKRE 55
Query: 61 DKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAED 120
D+G+P EG+ ++ EG E +G SE E KP+ EGKP S+ +P S+ RAA KRPAED
Sbjct: 56 DEGEPGDEGQLED-----EGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAED 110
Query: 121 DVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFL 180
VPRKAKRKT++G K+ +E + + + S+E+M+RE ++++ Q+E RK KQK+G F
Sbjct: 111 YVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRK-KQKMGGFH 169
Query: 181 WMQRNLQDPFYPRGPREFRG--GCRAPRRDIEDIPYV 215
WMQR++QDPF PRG R RG G ++D+ED+PYV
Sbjct: 170 WMQRDVQDPFAPRGQRGVRGVRGGGRGQKDLEDVPYV 206
>gi|55749431 transcription elongation factor A (SII)-like 3 [Homo
sapiens]
Length = 200
Score = 182 bits (462), Expect = 2e-46
Identities = 103/217 (47%), Positives = 143/217 (65%), Gaps = 19/217 (8%)
Query: 1 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK 60
MEK Y++NEG N+GK E+E +P DE K + E++K + EGKTE +GK DE
Sbjct: 1 MEKPYNKNEGNLENEGKPEDEVEPDDEGKSD-----EEEKPDVEGKTECEGKREDE---- 51
Query: 61 DKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAED 120
G+P EG+ ++ EG E +G SE EGKP+ EGKP S+ +P S+ RAA KRPAED
Sbjct: 52 --GEPGDEGQLED-----EGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAED 104
Query: 121 DVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFL 180
VPRKAKRKT++G K+ +E + + + S+E+M+RE ++++ Q+E RK KQK+G F
Sbjct: 105 YVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRK-KQKMGGFH 163
Query: 181 WMQRNLQDPFYPRGPREFRG--GCRAPRRDIEDIPYV 215
WMQR++QDPF PRG R RG G +R + DIPY+
Sbjct: 164 WMQRDVQDPFAPRGQRGVRGVRGGGRGQRGLHDIPYL 200
>gi|14249718 transcription elongation factor A (SII)-like 3 [Homo
sapiens]
Length = 200
Score = 182 bits (462), Expect = 2e-46
Identities = 103/217 (47%), Positives = 143/217 (65%), Gaps = 19/217 (8%)
Query: 1 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK 60
MEK Y++NEG N+GK E+E +P DE K + E++K + EGKTE +GK DE
Sbjct: 1 MEKPYNKNEGNLENEGKPEDEVEPDDEGKSD-----EEEKPDVEGKTECEGKREDE---- 51
Query: 61 DKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAED 120
G+P EG+ ++ EG E +G SE EGKP+ EGKP S+ +P S+ RAA KRPAED
Sbjct: 52 --GEPGDEGQLED-----EGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAED 104
Query: 121 DVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFL 180
VPRKAKRKT++G K+ +E + + + S+E+M+RE ++++ Q+E RK KQK+G F
Sbjct: 105 YVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRK-KQKMGGFH 163
Query: 181 WMQRNLQDPFYPRGPREFRG--GCRAPRRDIEDIPYV 215
WMQR++QDPF PRG R RG G +R + DIPY+
Sbjct: 164 WMQRDVQDPFAPRGQRGVRGVRGGGRGQRGLHDIPYL 200
>gi|118600971 transcription elongation factor A (SII)-like 6 [Homo
sapiens]
Length = 183
Score = 157 bits (398), Expect = 5e-39
Identities = 87/190 (45%), Positives = 126/190 (66%), Gaps = 17/190 (8%)
Query: 1 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK 60
MEK Y++NEG N+GK E+E +P DE K + E++K + EGKTE +GK K
Sbjct: 1 MEKPYNKNEGNLENEGKPEDEVEPDDEGKSD-----EEEKPDAEGKTECEGKR------K 49
Query: 61 DKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAED 120
+G+P EG+ ++ +G E +G SE EGKP+ EGKP S+ +P + RAA KRPA D
Sbjct: 50 AEGEPGDEGQLED-----KGSQEKQGKSEGEGKPQGEGKPASQAKPEGQPRAAEKRPAGD 104
Query: 121 DVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFL 180
VPRKAKRKT++G K+ +E + + + S+E+M+RE ++++ Q+E RK KQK+G F
Sbjct: 105 YVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRK-KQKMGGFH 163
Query: 181 WMQRNLQDPF 190
WMQR++QDPF
Sbjct: 164 WMQRDVQDPF 173
>gi|55743140 WW domain binding protein 5 [Homo sapiens]
Length = 104
Score = 63.2 bits (152), Expect = 2e-10
Identities = 40/108 (37%), Positives = 58/108 (53%), Gaps = 7/108 (6%)
Query: 84 MEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAEDDVPRKAKRKTNKGLAHYLKEYKE 143
M+ + EGKPE E +P+ E EP E + + E++ KAK + L L+E+KE
Sbjct: 1 MKSCQKMEGKPENESEPKHEEEPKPEEKPEEEEKLEEEA--KAKGTFRERLIQSLQEFKE 58
Query: 144 AIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFLW-MQRNLQDPF 190
IH+ + SNEDM RE D + DE R+ + KL W + RN P+
Sbjct: 59 DIHNRHLSNEDMFREVDEI----DEIRRVRNKLIVMRWKVNRNHPYPY 102
Score = 33.9 bits (76), Expect = 0.11
Identities = 16/40 (40%), Positives = 25/40 (62%), Gaps = 5/40 (12%)
Query: 9 EGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTE 48
EG N+ + ++EE+P+ E KPE E++KLE E K +
Sbjct: 8 EGKPENESEPKHEEEPKPEEKPE-----EEEKLEEEAKAK 42
>gi|55743147 WW domain binding protein 5 [Homo sapiens]
Length = 104
Score = 63.2 bits (152), Expect = 2e-10
Identities = 40/108 (37%), Positives = 58/108 (53%), Gaps = 7/108 (6%)
Query: 84 MEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAEDDVPRKAKRKTNKGLAHYLKEYKE 143
M+ + EGKPE E +P+ E EP E + + E++ KAK + L L+E+KE
Sbjct: 1 MKSCQKMEGKPENESEPKHEEEPKPEEKPEEEEKLEEEA--KAKGTFRERLIQSLQEFKE 58
Query: 144 AIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFLW-MQRNLQDPF 190
IH+ + SNEDM RE D + DE R+ + KL W + RN P+
Sbjct: 59 DIHNRHLSNEDMFREVDEI----DEIRRVRNKLIVMRWKVNRNHPYPY 102
Score = 33.9 bits (76), Expect = 0.11
Identities = 16/40 (40%), Positives = 25/40 (62%), Gaps = 5/40 (12%)
Query: 9 EGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTE 48
EG N+ + ++EE+P+ E KPE E++KLE E K +
Sbjct: 8 EGKPENESEPKHEEEPKPEEKPE-----EEEKLEEEAKAK 42
>gi|10047100 WW domain binding protein 5 [Homo sapiens]
Length = 104
Score = 63.2 bits (152), Expect = 2e-10
Identities = 40/108 (37%), Positives = 58/108 (53%), Gaps = 7/108 (6%)
Query: 84 MEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAEDDVPRKAKRKTNKGLAHYLKEYKE 143
M+ + EGKPE E +P+ E EP E + + E++ KAK + L L+E+KE
Sbjct: 1 MKSCQKMEGKPENESEPKHEEEPKPEEKPEEEEKLEEEA--KAKGTFRERLIQSLQEFKE 58
Query: 144 AIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFLW-MQRNLQDPF 190
IH+ + SNEDM RE D + DE R+ + KL W + RN P+
Sbjct: 59 DIHNRHLSNEDMFREVDEI----DEIRRVRNKLIVMRWKVNRNHPYPY 102
Score = 33.9 bits (76), Expect = 0.11
Identities = 16/40 (40%), Positives = 25/40 (62%), Gaps = 5/40 (12%)
Query: 9 EGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTE 48
EG N+ + ++EE+P+ E KPE E++KLE E K +
Sbjct: 8 EGKPENESEPKHEEEPKPEEKPE-----EEEKLEEEAKAK 42
>gi|55743145 WW domain binding protein 5 [Homo sapiens]
Length = 104
Score = 63.2 bits (152), Expect = 2e-10
Identities = 40/108 (37%), Positives = 58/108 (53%), Gaps = 7/108 (6%)
Query: 84 MEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAEDDVPRKAKRKTNKGLAHYLKEYKE 143
M+ + EGKPE E +P+ E EP E + + E++ KAK + L L+E+KE
Sbjct: 1 MKSCQKMEGKPENESEPKHEEEPKPEEKPEEEEKLEEEA--KAKGTFRERLIQSLQEFKE 58
Query: 144 AIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFLW-MQRNLQDPF 190
IH+ + SNEDM RE D + DE R+ + KL W + RN P+
Sbjct: 59 DIHNRHLSNEDMFREVDEI----DEIRRVRNKLIVMRWKVNRNHPYPY 102
Score = 33.9 bits (76), Expect = 0.11
Identities = 16/40 (40%), Positives = 25/40 (62%), Gaps = 5/40 (12%)
Query: 9 EGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTE 48
EG N+ + ++EE+P+ E KPE E++KLE E K +
Sbjct: 8 EGKPENESEPKHEEEPKPEEKPE-----EEEKLEEEAKAK 42
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 60.5 bits (145), Expect = 1e-09
Identities = 52/199 (26%), Positives = 82/199 (41%), Gaps = 6/199 (3%)
Query: 2 EKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKD 61
E+ E + + E E++ + ER+ E + K + + + + D E D
Sbjct: 317 ERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSD 376
Query: 62 KGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRP-AED 120
+ K S K ERE E E E ERE + E E + E E E E KR ED
Sbjct: 377 RNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREED 436
Query: 121 DVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKR----KSKQKL 176
+ +RK + L Y+E + + RE++ A+ ++E+R K ++L
Sbjct: 437 EEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRL 496
Query: 177 GAFLW-MQRNLQDPFYPRG 194
FL + DP Y RG
Sbjct: 497 KEFLEDYDDDRDDPKYYRG 515
Score = 37.4 bits (85), Expect = 0.010
Identities = 36/159 (22%), Positives = 72/159 (45%), Gaps = 7/159 (4%)
Query: 18 MENEEQPQDERKPEVTCTLED-KKLENEGKTENKGKTGDEEMLKDKGKPESEGEAKEGKS 76
+E EE +D E++ + KKLE E + K + +E+ K++ + E E E + +
Sbjct: 267 IEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKER---QEIEKERRERERERERERERR 323
Query: 77 EREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAEDDVPRKAKRKTNKGLAH 136
ERE E E E E+E + E E + + + + E R + D R+ NK +
Sbjct: 324 EREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSR 383
Query: 137 YLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQK 175
++ ++ + E RE + + + E+ + +++
Sbjct: 384 SREKSRDRERERERERE---RERERERERERERERERER 419
Score = 32.3 bits (72), Expect = 0.31
Identities = 26/110 (23%), Positives = 50/110 (45%), Gaps = 17/110 (15%)
Query: 19 ENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDE-----EMLKDKGKPESEGEAKE 73
++ + P+ R + L D++ E E ++ + +E + L +G P+ + E +
Sbjct: 505 DDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQR 564
Query: 74 GKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKR--PAEDD 121
ME +ER +P+I+ +PESE E + KR P E++
Sbjct: 565 ----------MEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEE 604
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 58.5 bits (140), Expect = 4e-09
Identities = 44/121 (36%), Positives = 60/121 (49%), Gaps = 13/121 (10%)
Query: 7 ENEGMASNQGKMENEEQPQDERKPEVTCTLEDKK-----LENEGKTENKGKTGDEEMLKD 61
E EG +GK E EE+ ++ E E+++ E EGK E +G+ G+ E +
Sbjct: 813 EVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGE 872
Query: 62 KGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGE-PGSETRAAGKRPAED 120
+G+ E E E EG+ E EGE E G E EG EG+ E EGE G E GK E
Sbjct: 873 EGEGEGEEEEGEGEGEEEGEGE---GEEEEG----EGEGEEEGEGEGEEEEGEGKGEEEG 925
Query: 121 D 121
+
Sbjct: 926 E 926
Score = 58.2 bits (139), Expect = 5e-09
Identities = 41/106 (38%), Positives = 55/106 (51%), Gaps = 4/106 (3%)
Query: 2 EKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKD 61
E+ E EG +G+ E EE +E + E E ++ E E + E G+EE +
Sbjct: 827 EEEEEEGEG-EEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEG 885
Query: 62 KGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPG 107
+G+ E EGE +E + E EGE E EG E E E EGK E EGE G
Sbjct: 886 EGEEEGEGEGEEEEGEGEGEEEGEGEGEEE---EGEGKGEEEGEEG 928
Score = 57.8 bits (138), Expect = 7e-09
Identities = 43/128 (33%), Positives = 65/128 (50%), Gaps = 5/128 (3%)
Query: 7 ENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPE 66
E EG +G+ E EE+ + E + E E ++ E EGK E +G+ G+ E +++G E
Sbjct: 882 EGEGEGEEEGEGEGEEE-EGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEG--E 938
Query: 67 SEGEAKEGKSEREGESEMEGGSER-EGKPEIEGKPESEGEPGSETRAAGKRPAEDDVPRK 125
EGE EG+ E E E E EG E EG+ E EG+ E E G G+ E++ +
Sbjct: 939 GEGEDGEGEGEEE-EGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEE 997
Query: 126 AKRKTNKG 133
+ +G
Sbjct: 998 EGEEEGEG 1005
Score = 55.5 bits (132), Expect = 3e-08
Identities = 48/170 (28%), Positives = 80/170 (47%), Gaps = 12/170 (7%)
Query: 7 ENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPE 66
E EG +G+ E+ E +E + E E ++ E EG+ E +G+ EE + + E
Sbjct: 934 EEEG----EGEGEDGEGEGEEEEGE----WEGEEEEGEGEGEEEGEGEGEEGEGEGEEEE 985
Query: 67 SEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGE-PGSETRAAGKRPAEDDVPRK 125
EGE +E + E EGE E EG E EG+ E E + E EGE G E G+ E++ +
Sbjct: 986 GEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGE---EEEGEEE 1042
Query: 126 AKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQK 175
+ + +G + +E + ++ E + ++ K+ SK K
Sbjct: 1043 GEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIK 1092
Score = 54.3 bits (129), Expect = 8e-08
Identities = 42/120 (35%), Positives = 58/120 (48%), Gaps = 19/120 (15%)
Query: 7 ENEGMASNQGKMENE-EQPQDERKPEVTCTLEDKKLENEGKTENKGKTGD--EEMLKDKG 63
E E +GK E E E+ + ER+ E ++++ E K E +G G+ EE + +G
Sbjct: 746 EEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRG 805
Query: 64 KPESE------GEAKEGKSEREGESEMEGGSEREG----------KPEIEGKPESEGEPG 107
+ + E GE +EGK ERE E E G E EG + E EGK E EGE G
Sbjct: 806 EEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEG 865
Score = 54.3 bits (129), Expect = 8e-08
Identities = 42/127 (33%), Positives = 61/127 (48%), Gaps = 10/127 (7%)
Query: 7 ENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPE 66
E EG +G+ E ++E + E ED E EG+ E G+EE + +G+ E
Sbjct: 916 EGEGKGEEEGEEGEGEGEEEEGEGEG----EDG--EGEGEEEEGEWEGEEEEGEGEGEEE 969
Query: 67 SEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAEDDVPRKA 126
EGE +EG+ E E E G E EG E EG+ E EGE E G+ E +V +
Sbjct: 970 GEGEGEEGEGEGEEEEGEGEGEEEEG--EEEGEEEGEGE--EEGEGEGEEEEEGEVEGEV 1025
Query: 127 KRKTNKG 133
+ + +G
Sbjct: 1026 EGEEGEG 1032
Score = 53.1 bits (126), Expect = 2e-07
Identities = 35/114 (30%), Positives = 55/114 (48%), Gaps = 14/114 (12%)
Query: 2 EKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKD 61
E+ E EG +G+ E E + ++E + EV +E ++ E EG+ E + G+E
Sbjct: 991 EEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEER---- 1046
Query: 62 KGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGK 115
E EGE +E + RE E E EGK + G+ E+E + G E + K
Sbjct: 1047 ----EKEGEGEENRRNREEE------EEEEGKYQETGEEENERQDGEEYKKVSK 1090
Score = 51.6 bits (122), Expect = 5e-07
Identities = 44/135 (32%), Positives = 66/135 (48%), Gaps = 15/135 (11%)
Query: 2 EKLYSENEGMASNQGK-MENE-EQPQDERKPEVTCTLEDK-----------KLENEGKTE 48
E+ E EG +G+ +E E E+ + ERK E E+K + E EG+ E
Sbjct: 747 EEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGE 806
Query: 49 NKGKTGDEEMLK-DKGKPESEGEAKEGKSERE-GESEMEGGSEREGKPEIEGKPESEGEP 106
K + G+ E + ++GK E E E +EG+ E E GE E E G E + E +G+ E E
Sbjct: 807 EKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGE 866
Query: 107 GSETRAAGKRPAEDD 121
G E G+ E++
Sbjct: 867 GEEEGEEGEGEGEEE 881
Score = 51.2 bits (121), Expect = 6e-07
Identities = 40/134 (29%), Positives = 64/134 (47%), Gaps = 4/134 (2%)
Query: 2 EKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGK-TENKGKTGDEEMLK 60
EK +E E G+ + +++ + + E +E+ E G+ E +G +EE +
Sbjct: 693 EKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKE 752
Query: 61 DKGKPESEGEAKEGKSER-EGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAE 119
+GK E EGE EG+ E+ EGE + E + +E K E EG + EGE ET G+ E
Sbjct: 753 GEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEG-DQGEGEE-EETEGRGEEKEE 810
Query: 120 DDVPRKAKRKTNKG 133
+ + KG
Sbjct: 811 GGEVEGGEVEEGKG 824
Score = 51.2 bits (121), Expect = 6e-07
Identities = 42/142 (29%), Positives = 61/142 (42%), Gaps = 12/142 (8%)
Query: 7 ENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKT-----GDEEMLKD 61
E EG +G+ E EE + + E E+++ E EG+ E +G+ G+EE +
Sbjct: 961 EGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEE---E 1017
Query: 62 KGKPESEGEAKEGKSEREGESEMEGGSER----EGKPEIEGKPESEGEPGSETRAAGKRP 117
+G+ E E E +EG+ E E E E G ER EG+ + E E E G +
Sbjct: 1018 EGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEEN 1077
Query: 118 AEDDVPRKAKRKTNKGLAHYLK 139
D K KG Y K
Sbjct: 1078 ERQDGEEYKKVSKIKGSVKYGK 1099
Score = 50.1 bits (118), Expect = 1e-06
Identities = 42/102 (41%), Positives = 58/102 (56%), Gaps = 15/102 (14%)
Query: 7 ENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPE 66
E EG +G+ E EE+ + E E+++ E EG+ E +G+ G+EE + +GK E
Sbjct: 875 EGEG-EEEEGEGEGEEEGEGEG--------EEEEGEGEGEEEGEGE-GEEE--EGEGKGE 922
Query: 67 SEGEAKEGK-SEREGESEMEGGSEREGKPEIEGKPESEGEPG 107
EGE EG+ E EGE E E G E EG+ E EG+ E E E G
Sbjct: 923 EEGEEGEGEGEEEEGEGEGEDG-EGEGEEE-EGEWEGEEEEG 962
Score = 48.9 bits (115), Expect = 3e-06
Identities = 39/121 (32%), Positives = 61/121 (50%), Gaps = 9/121 (7%)
Query: 7 ENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTG-----DEEMLKD 61
E E ++G+ E E + E+ E+ E KK + E + + + + G ++EM +
Sbjct: 673 EREKGEKDKGRGEMERPGEGEK--ELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEG 730
Query: 62 KGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPE-SEGEPGSETRAAGKRPAED 120
+ EGE +EG E E E E EG E EG+ E+EG+ E EGE E RA + E+
Sbjct: 731 GEEEHGEGEEEEGDREEEEEKEGEGKEEGEGE-EVEGEREKEEGERKKEERAGKEEKGEE 789
Query: 121 D 121
+
Sbjct: 790 E 790
Score = 48.9 bits (115), Expect = 3e-06
Identities = 41/124 (33%), Positives = 58/124 (46%), Gaps = 12/124 (9%)
Query: 7 ENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPE 66
E EG +G+ E EE +E E E+++ E EG+ E +G+ G+EE + +G+ E
Sbjct: 851 EEEG--EGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGE-GEEEEGEGEGEEE 907
Query: 67 SEGEAKE----GKSEREGES-----EMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRP 117
EGE +E GK E EGE E E G E EG+ E G E G+
Sbjct: 908 GEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGE 967
Query: 118 AEDD 121
E +
Sbjct: 968 EEGE 971
Score = 44.3 bits (103), Expect = 8e-05
Identities = 40/120 (33%), Positives = 57/120 (47%), Gaps = 10/120 (8%)
Query: 19 ENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPESEGEAKEGKSER 78
E E+ +D+ + E+ E +K E K E K + G+E+ K++ +G KE E
Sbjct: 673 EREKGEKDKGRGEMERPGEGEK-ELAEKEEWKKRDGEEQEQKER----EQGHQKERNQEM 727
Query: 79 E--GESEMEGGSEREGKPEIEGKPESEG-EPGSETRAAGKRPAEDDVPRKAKR--KTNKG 133
E GE E G E EG E E + E EG E G G+R E+ +K +R K KG
Sbjct: 728 EEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKG 787
Score = 32.3 bits (72), Expect = 0.31
Identities = 32/126 (25%), Positives = 55/126 (43%), Gaps = 8/126 (6%)
Query: 8 NEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPES 67
+EG A + G+ E+ + + + E + + + E + K K E ++ G+ E
Sbjct: 637 SEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGE--MERPGEGEK 694
Query: 68 EGEAKEGKSEREGES----EMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAEDDVP 123
E KE +R+GE E E G ++E E+E E E G E G R E++
Sbjct: 695 ELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEE--GDREEEEEKE 752
Query: 124 RKAKRK 129
+ K +
Sbjct: 753 GEGKEE 758
Score = 29.3 bits (64), Expect = 2.6
Identities = 21/96 (21%), Positives = 41/96 (42%), Gaps = 4/96 (4%)
Query: 42 ENEGKTENKGKTGDEEMLKDKGKPESEGEAKEGKSEREGESEMEGGSEREGKP----EIE 97
E EG ++KG +E+ ++ + ++ K+E + + EGK E E
Sbjct: 589 EKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGEAE 648
Query: 98 GKPESEGEPGSETRAAGKRPAEDDVPRKAKRKTNKG 133
PE G+ E ++G +D+ K ++ +G
Sbjct: 649 DGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRG 684
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 53.1 bits (126), Expect = 2e-07
Identities = 34/114 (29%), Positives = 55/114 (48%), Gaps = 3/114 (2%)
Query: 19 ENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPESEGEAKEGKSER 78
E EE + E + E ++K+ E + E K KT + E K+K + E + + K K +
Sbjct: 12 ETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKE 71
Query: 79 EGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAEDDVPRKAKRKTNK 132
E E E E E E K E E + EG + + ++ E++ +K +RKT K
Sbjct: 72 EEEREEEEEEEEEEKEEEE---KEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122
Score = 30.4 bits (67), Expect = 1.2
Identities = 27/116 (23%), Positives = 49/116 (42%), Gaps = 20/116 (17%)
Query: 60 KDKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAE 119
K + + E E E + E+EG+ + + +R+ E E +T+ KR +
Sbjct: 7 KKETEETEETEETEEEEEKEGKRKEKRKEKRK-----------EKEKKKKTKETEKRKEK 55
Query: 120 DDVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQK 175
++ +K KRK K +E +E E+ E + K + +RK K+K
Sbjct: 56 EEEEKKRKRKRKKKKEEEEREEEE---------EEEEEEKEEEEKEEGRRRKKKKK 102
Score = 29.3 bits (64), Expect = 2.6
Identities = 21/87 (24%), Positives = 40/87 (45%), Gaps = 8/87 (9%)
Query: 7 ENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPE 66
E EG + K + +E+ + ++ E E ++ E + K + K K +EE +++ + E
Sbjct: 24 EKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEE 83
Query: 67 SEGEAKE--------GKSEREGESEME 85
E E +E K +R + E E
Sbjct: 84 EEKEEEEKEEGRRRKKKKKRRRKEEEE 110
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 52.4 bits (124), Expect = 3e-07
Identities = 44/130 (33%), Positives = 61/130 (46%), Gaps = 20/130 (15%)
Query: 19 ENEEQPQDE------RKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPESEGEAK 72
E EE+P+ E +K V T + K E K E +G+ +EE +D+G +A+
Sbjct: 494 EKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEE--EDEG--AKSDQAE 549
Query: 73 EGKSEREGESEMEGGSEREGK-------PEIEGKPESEGEPGSETRAAGKRPAED---DV 122
EG SE+EG SE E G + EG+ E E K E + E SE A + D +
Sbjct: 550 EGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEK 609
Query: 123 PRKAKRKTNK 132
P KAK K
Sbjct: 610 PEKAKSPVPK 619
Score = 43.5 bits (101), Expect = 1e-04
Identities = 36/128 (28%), Positives = 57/128 (44%), Gaps = 11/128 (8%)
Query: 2 EKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKD 61
EK+ + E K + E ++E EV + K+ E +T+ +GK +E K+
Sbjct: 716 EKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKE 775
Query: 62 K----GKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEG-----EPGSETRA 112
K G E EG K K R+ + + G E EGK E+E + + +G E G T
Sbjct: 776 KAGGEGGSEEEGSDKGAKGSRKEDIAVNG--EVEGKEEVEQETKEKGSGREEEKGVVTNG 833
Query: 113 AGKRPAED 120
PA++
Sbjct: 834 LDLSPADE 841
Score = 41.6 bits (96), Expect = 5e-04
Identities = 47/213 (22%), Positives = 87/213 (40%), Gaps = 28/213 (13%)
Query: 17 KMENEEQPQDERKPEVT----CTLEDKKLENEGKTENKGKTGDEEMLKDKGK-------- 64
K+E+E+ +E +T +++++K E + E + + +EE+ K
Sbjct: 461 KVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEV 520
Query: 65 PESEGEAKEGKSEREGESEMEGGSE---REGKPEIEG---KPESEGEPGSETRAAGKRPA 118
E EGE +E + + E E E EG EG E EG K E E E G A A
Sbjct: 521 KEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEA 580
Query: 119 EDDVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGA 178
E +K + K+ + + +E + D + + + V+++ + K
Sbjct: 581 EAKEEKKVEEKSEE-----VATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSP- 634
Query: 179 FLWMQRNLQDPFYPRGPREFRGGCRAPRRDIED 211
++ + P P+ P E +G P+ +E+
Sbjct: 635 ---VEEKGKSP-VPKSPVEEKGKSPVPKSPVEE 663
Score = 39.7 bits (91), Expect = 0.002
Identities = 37/129 (28%), Positives = 54/129 (41%), Gaps = 12/129 (9%)
Query: 9 EGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPESE 68
EG + +G E EE Q+E + E E+ + + E K E K EE+ K E
Sbjct: 550 EGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKS----EEVAT---KEELV 602
Query: 69 GEAKEGKSEREGESEMEGGSEREGKPEIEGKP-ESEGE---PGSETRAAGKRPA-EDDVP 123
+AK K E+ + E +GK + P E +G+ P S GK P + V
Sbjct: 603 ADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVE 662
Query: 124 RKAKRKTNK 132
K K +K
Sbjct: 663 EKGKSPVSK 671
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 52.4 bits (124), Expect = 3e-07
Identities = 44/130 (33%), Positives = 61/130 (46%), Gaps = 20/130 (15%)
Query: 19 ENEEQPQDE------RKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPESEGEAK 72
E EE+P+ E +K V T + K E K E +G+ +EE +D+G +A+
Sbjct: 118 EKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEE--EDEG--AKSDQAE 173
Query: 73 EGKSEREGESEMEGGSEREGK-------PEIEGKPESEGEPGSETRAAGKRPAED---DV 122
EG SE+EG SE E G + EG+ E E K E + E SE A + D +
Sbjct: 174 EGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEK 233
Query: 123 PRKAKRKTNK 132
P KAK K
Sbjct: 234 PEKAKSPVPK 243
Score = 43.5 bits (101), Expect = 1e-04
Identities = 36/128 (28%), Positives = 57/128 (44%), Gaps = 11/128 (8%)
Query: 2 EKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKD 61
EK+ + E K + E ++E EV + K+ E +T+ +GK +E K+
Sbjct: 340 EKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKE 399
Query: 62 K----GKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEG-----EPGSETRA 112
K G E EG K K R+ + + G E EGK E+E + + +G E G T
Sbjct: 400 KAGGEGGSEEEGSDKGAKGSRKEDIAVNG--EVEGKEEVEQETKEKGSGREEEKGVVTNG 457
Query: 113 AGKRPAED 120
PA++
Sbjct: 458 LDLSPADE 465
Score = 41.6 bits (96), Expect = 5e-04
Identities = 47/213 (22%), Positives = 87/213 (40%), Gaps = 28/213 (13%)
Query: 17 KMENEEQPQDERKPEVT----CTLEDKKLENEGKTENKGKTGDEEMLKDKGK-------- 64
K+E+E+ +E +T +++++K E + E + + +EE+ K
Sbjct: 85 KVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEV 144
Query: 65 PESEGEAKEGKSEREGESEMEGGSE---REGKPEIEG---KPESEGEPGSETRAAGKRPA 118
E EGE +E + + E E E EG EG E EG K E E E G A A
Sbjct: 145 KEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEA 204
Query: 119 EDDVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGA 178
E +K + K+ + + +E + D + + + V+++ + K
Sbjct: 205 EAKEEKKVEEKSEE-----VATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSP- 258
Query: 179 FLWMQRNLQDPFYPRGPREFRGGCRAPRRDIED 211
++ + P P+ P E +G P+ +E+
Sbjct: 259 ---VEEKGKSP-VPKSPVEEKGKSPVPKSPVEE 287
Score = 39.7 bits (91), Expect = 0.002
Identities = 37/129 (28%), Positives = 54/129 (41%), Gaps = 12/129 (9%)
Query: 9 EGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPESE 68
EG + +G E EE Q+E + E E+ + + E K E K EE+ K E
Sbjct: 174 EGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKS----EEVAT---KEELV 226
Query: 69 GEAKEGKSEREGESEMEGGSEREGKPEIEGKP-ESEGE---PGSETRAAGKRPA-EDDVP 123
+AK K E+ + E +GK + P E +G+ P S GK P + V
Sbjct: 227 ADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVE 286
Query: 124 RKAKRKTNK 132
K K +K
Sbjct: 287 EKGKSPVSK 295
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 50.8 bits (120), Expect = 8e-07
Identities = 49/208 (23%), Positives = 88/208 (42%), Gaps = 25/208 (12%)
Query: 3 KLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDK 62
++ + EG + + + E + +++RK E E ++ GK E KG+ EE + K
Sbjct: 44 EIETRKEGKKERESERKKERREREKRKRE----REKERKRERGKKEKKGERKKEERERKK 99
Query: 63 GKPESEGEAKEGKSEREGESEME-GGSEREGKPEIEGKPESEGEPGSETRAAGKRPAEDD 121
+ E E + E K +R+ + + E G + +EGK E E K E + E E + ++
Sbjct: 100 RRREKENKEGEEKEKRKKKEKKERGRTSKEGK-ERERKEERKREERKERERKKEEREKER 158
Query: 122 VPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNE------------DMIREFDNMAKVQDEK 169
++ K++ K + +E KE E RE K ++E+
Sbjct: 159 ERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEER 218
Query: 170 RKSKQKLGAFLWMQRNLQDPFYPRGPRE 197
+K +QK W ++ RG RE
Sbjct: 219 KKERQKDRQTNWREKE-------RGKRE 239
Score = 43.5 bits (101), Expect = 1e-04
Identities = 35/166 (21%), Positives = 79/166 (47%), Gaps = 14/166 (8%)
Query: 10 GMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPESEG 69
G S + E E + + E K E E ++ + + E + + ++E +++GK E +G
Sbjct: 33 GWQSEIREREREIETRKEGKKE----RESERKKERREREKRKREREKERKRERGKKEKKG 88
Query: 70 EAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAEDDVPRKAKRK 129
E K K ERE + +EG+ + + K + + E G ++ +R +++ R+ +++
Sbjct: 89 ERK--KEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKE 146
Query: 130 TNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQK 175
+ KE +E + E RE + + ++E+++ ++K
Sbjct: 147 RER-----KKEEREKERE---RKERKKRERKQVGEKEEERKEKERK 184
Score = 42.7 bits (99), Expect = 2e-04
Identities = 37/133 (27%), Positives = 59/133 (44%), Gaps = 8/133 (6%)
Query: 2 EKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKG-KTGDEEMLK 60
+K + G S +GK E + ++ERK E E KK E E + E K K + + +
Sbjct: 116 KKKEKKERGRTSKEGK---ERERKEERKREERKERERKKEEREKERERKERKKRERKQVG 172
Query: 61 DKGKPESEGEAKEGK----SEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKR 116
+K + E E KE K + +E + E E RE K E + K E + E + + +
Sbjct: 173 EKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWRE 232
Query: 117 PAEDDVPRKAKRK 129
RK ++K
Sbjct: 233 KERGKRERKERKK 245
Score = 40.0 bits (92), Expect = 0.001
Identities = 40/149 (26%), Positives = 64/149 (42%), Gaps = 10/149 (6%)
Query: 32 VTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPESEGEAKEGKSEREGESEMEGGSERE 91
V+C+ K G + E + +GK E E E K+ + ERE + + E+E
Sbjct: 20 VSCSHISKPCTQPGWQSEIREREREIETRKEGKKERESERKKERRERE---KRKREREKE 76
Query: 92 GKPEIEGKPESEGEPGSETRAAGKR-----PAEDDVPRKAKRKTNKGLAHYLKEYKEAIH 146
K E GK E +GE E R KR E + K K+K K KE KE
Sbjct: 77 RKRE-RGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERER 135
Query: 147 DMNFSNEDMIREFDNMAKVQDEKRKSKQK 175
E+ +E + + ++++R+ K++
Sbjct: 136 KEERKREER-KERERKKEEREKERERKER 163
Score = 38.9 bits (89), Expect = 0.003
Identities = 39/162 (24%), Positives = 68/162 (41%), Gaps = 10/162 (6%)
Query: 2 EKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENK-----GKTGDE 56
EK G +G+ + EE+ + +R+ E E ++ E K E K K G E
Sbjct: 74 EKERKRERGKKEKKGERKKEERERKKRRREKE-NKEGEEKEKRKKKEKKERGRTSKEGKE 132
Query: 57 EMLKDKGKPES--EGEAKEGKSEREGESEMEGGSERE--GKPEIEGKPESEGEPGSETRA 112
K++ K E E E K+ + E+E E + ER+ G+ E E K + E R
Sbjct: 133 RERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERN 192
Query: 113 AGKRPAEDDVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNED 154
+R E + + +RK + K+ ++ N+ ++
Sbjct: 193 RKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKE 234
>gi|21361639 DIPB protein [Homo sapiens]
Length = 344
Score = 50.1 bits (118), Expect = 1e-06
Identities = 36/117 (30%), Positives = 59/117 (50%), Gaps = 10/117 (8%)
Query: 7 ENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPE 66
E G + K+E E + + E E+ + E E ++E + +T EE +D+ E
Sbjct: 74 EGAGKEEAEVKVEQEREIESEAG-------EESESEEESESEEESET--EEESEDESDEE 124
Query: 67 SEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAEDDVP 123
SE +++E + E E ESE E ++ EG+ E EG+ E+E E E +R A+ P
Sbjct: 125 SEEDSEE-EMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRKCP 180
Score = 46.2 bits (108), Expect = 2e-05
Identities = 32/112 (28%), Positives = 58/112 (51%), Gaps = 4/112 (3%)
Query: 37 EDKKLENEGKTENKGKTGDEEMLKDKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEI 96
+++++E+E E++ + E + + + ESE E+ E +SE + E EME E E + +
Sbjct: 87 QEREIESEAGEESESEEESESEEESETEEESEDESDE-ESEEDSEEEMEDEQESEAEEDN 145
Query: 97 EGKPESEGEPGSETRAAGKRPAEDDVPRKAKRKT---NKGLAHYLKEYKEAI 145
+ + ESE E +E + E + R AKRK L+ Y +E ++ I
Sbjct: 146 QEEGESEAEGETEAESEFDPEIEMEAERVAKRKCPDHGLDLSTYCQEDRQLI 197
Score = 39.7 bits (91), Expect = 0.002
Identities = 30/88 (34%), Positives = 51/88 (57%), Gaps = 10/88 (11%)
Query: 6 SENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKP 65
SE+E + ++ + E EE+ +DE E + ED + E E + E++ + ++E +G+
Sbjct: 99 SESEEESESEEESETEEESEDESDEE---SEEDSEEEMEDEQESEAEEDNQE----EGES 151
Query: 66 ESEGEAKEGKSEREGESEMEGGSEREGK 93
E+EGE E +SE + E EME +ER K
Sbjct: 152 EAEGET-EAESEFDPEIEME--AERVAK 176
>gi|11225260 DNA topoisomerase I [Homo sapiens]
Length = 765
Score = 49.7 bits (117), Expect = 2e-06
Identities = 50/201 (24%), Positives = 86/201 (42%), Gaps = 22/201 (10%)
Query: 19 ENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPESEGEAKEGKSER 78
E++++ E+ +D + +++ K + K K G E KDK K + + KE K
Sbjct: 37 EHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHKDRDKEKRKEEKVRA 96
Query: 79 EGESEMEGGSER--EGKPEIEGKPESEG--EPGSETRAAGKRPAEDD----VPRKAKRKT 130
G+++++ E P+I+ +PE +G P E KRP ++D P+K K +
Sbjct: 97 SGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPRDEDDADYKPKKIKTED 156
Query: 131 NKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKV--QDEKRKSKQKLGAFLWMQRNLQD 188
K KE K + + + D KV D K+K +K W + ++
Sbjct: 157 TK------KEKKRKLEEEEDGKLKKPKNKDKDKKVPEPDNKKKKPKKEEEQKW--KWWEE 208
Query: 189 PFYPRGPR----EFRGGCRAP 205
YP G + E +G AP
Sbjct: 209 ERYPEGIKWKFLEHKGPVFAP 229
Score = 30.0 bits (66), Expect = 1.5
Identities = 34/164 (20%), Positives = 63/164 (38%), Gaps = 9/164 (5%)
Query: 18 MENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPESEGEAKEGKSE 77
+ N+ Q + + + + +DK + E + + K D E K + E K E
Sbjct: 6 LHNDSQIEADFRLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKH--KE 63
Query: 78 REGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAG----KRPAEDDVPRKAKRKTNKG 133
+E +G SE+ + E E + RA+G K+ E+ + K
Sbjct: 64 KEKTKHKDGSSEKHKDKHKDRDKEKRKE--EKVRASGDAKIKKEKENGFSSPPQIKDEPE 121
Query: 134 LAHYLKEYKEAIHDMNFSNEDMIREF-DNMAKVQDEKRKSKQKL 176
Y KE I + ++ ++ K +D K++ K+KL
Sbjct: 122 DDGYFVPPKEDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKL 165
>gi|69354671 ATP-binding cassette, sub-family F, member 1 isoform a
[Homo sapiens]
Length = 845
Score = 49.7 bits (117), Expect = 2e-06
Identities = 43/153 (28%), Positives = 71/153 (46%), Gaps = 16/153 (10%)
Query: 19 ENEEQPQDERKPEVTCTLE----DKKLENEGKTENKGKTGDEEMLKDKGKPESEGEAKEG 74
++EE+ ++E+ P E +K + E + KGK G EE K K KP+++ A +
Sbjct: 139 QSEEEEEEEKHPPKPAKPEKNRINKAVSEEQQPALKGKKGKEEKSKGKAKPQNKFAALDN 198
Query: 75 KSE-REGESEMEGGSEREGK---PEIEGKPESEGEPGSETRAAGKRPAED---DVPRKAK 127
+ E +E E E ++GK + E E EGE E G+ A+D + +K K
Sbjct: 199 EEEDKEEEIIKEKEPPKQGKEKAKKAEQGSEEEGEGEEEEEEGGESKADDPYAHLSKKEK 258
Query: 128 RKTNKGLAH-----YLKEYKEAIHDMNFSNEDM 155
+K K + + LK A +D + S +M
Sbjct: 259 KKLKKQMEYERQVASLKAANAAENDFSVSQAEM 291
Score = 39.3 bits (90), Expect = 0.003
Identities = 36/185 (19%), Positives = 81/185 (43%), Gaps = 19/185 (10%)
Query: 2 EKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKD 61
+K E E + + + + ++Q Q ++K + K ++++G+ + E LK
Sbjct: 49 DKQAGEEEKVLKEKEQQQQQQQQQQKKKRDTRKGRRKKDVDDDGEEKEL-----MERLKK 103
Query: 62 KGKPESEGEAKEGKSEREGESEMEGGS--------EREGKPEIEGKPESEGEPGSETRAA 113
P S+ E + + G + +GG+ + E + E E P +P E
Sbjct: 104 LSVPTSDEEDEVPAPKPRGGKKTKGGNVFAALIQDQSEEEEEEEKHPPKPAKP--EKNRI 161
Query: 114 GKRPAEDDVP----RKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEK 169
K +E+ P +K K + +KG A ++ ++ E++I+E + + +++
Sbjct: 162 NKAVSEEQQPALKGKKGKEEKSKGKAKPQNKFAALDNEEEDKEEEIIKEKEPPKQGKEKA 221
Query: 170 RKSKQ 174
+K++Q
Sbjct: 222 KKAEQ 226
>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
Length = 282
Score = 48.9 bits (115), Expect = 3e-06
Identities = 39/107 (36%), Positives = 53/107 (49%), Gaps = 12/107 (11%)
Query: 2 EKLYSENEGMASNQGKMENE---EQPQDERKPEVTCTLEDKKLENEGKTENKGK-TGDEE 57
E + +G GK E E+ +DE++ ED+K +GK GK GD++
Sbjct: 168 EDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEE------EDRKETGDGKENEDGKEKGDKK 221
Query: 58 MLKDKGKPESEGEAKEGKSEREGESEMEGGSEREG-KPEIEGKPESE 103
KD E E E ++GK E EG +E E G E+E K E EGK E E
Sbjct: 222 EGKDVKVKEDEKEREDGK-EDEGGNEEEAGKEKEDLKEEEEGKEEDE 267
Score = 46.2 bits (108), Expect = 2e-05
Identities = 39/118 (33%), Positives = 54/118 (45%), Gaps = 3/118 (2%)
Query: 2 EKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKD 61
E+ +E +G A + K E E+ E K ED K + +GK GK G+ E K+
Sbjct: 134 EEDQNEEKGEAGKEDKDEKGEEDGKEDK-NGNEKGEDAKEKEDGKKGEDGK-GNGEDGKE 191
Query: 62 KGKPESEGE-AKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPA 118
KG+ E E E KE +E E E G ++EGK + E E E G E + A
Sbjct: 192 KGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEA 249
Score = 45.4 bits (106), Expect = 4e-05
Identities = 44/174 (25%), Positives = 80/174 (45%), Gaps = 12/174 (6%)
Query: 7 ENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGK----TENKGKTGDEEMLKDK 62
EN A+ +G E +E E K E ED++ +NE K E+K + G+E+ +DK
Sbjct: 103 ENIEDATEKGG-EKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDK 161
Query: 63 GKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPG-SETRAAGKRPAEDD 121
E +AKE + ++GE G + + K E E + E E G + GK +
Sbjct: 162 NGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKK 221
Query: 122 VPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQK 175
+ K K ++ KE ++ D + E+ +E +++ + ++ K + + K
Sbjct: 222 EGKDVKVKEDE------KEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIK 269
Score = 43.1 bits (100), Expect = 2e-04
Identities = 44/191 (23%), Positives = 82/191 (42%), Gaps = 25/191 (13%)
Query: 1 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK 60
+E+ Y+EN + G+ + E P E++ +E K+ E TE G+ + +
Sbjct: 72 VEEDYNEN----AKNGEAKITEAPASEKE-----IVEVKEENIEDATEKGGEKKEAVAAE 122
Query: 61 DKGKPESEGEAKEGKSEREGESEMEGGSER---EGKPEIEGKPESE----------GEPG 107
K + E + E +E ++E +GE+ E E+ +GK + G + E GE G
Sbjct: 123 VKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDG 182
Query: 108 SETRAAGKRPAEDDVPRKAKRKTNKGLAH---YLKEYKEAIHDMNFSNEDMIREFDNMAK 164
GK ED+ + +++T G + K K+ D+ ++ RE +
Sbjct: 183 KGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDE 242
Query: 165 VQDEKRKSKQK 175
+E+ K+K
Sbjct: 243 GGNEEEAGKEK 253
Score = 31.2 bits (69), Expect = 0.70
Identities = 21/79 (26%), Positives = 39/79 (49%), Gaps = 3/79 (3%)
Query: 7 ENEGMASNQGKMENEEQPQ--DERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGK 64
E + + GK ENE+ + D+++ + ED+K +GK + G + K+ K
Sbjct: 199 EEDRKETGDGK-ENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLK 257
Query: 65 PESEGEAKEGKSEREGESE 83
E EG+ ++ E +G+ E
Sbjct: 258 EEEEGKEEDEIKEDDGKKE 276
Score = 30.0 bits (66), Expect = 1.5
Identities = 43/179 (24%), Positives = 70/179 (39%), Gaps = 31/179 (17%)
Query: 13 SNQGKMENEEQPQDERKPEVTCTLEDKKLE---NEGKTENKGKTGDEEMLKDKGKPESEG 69
S+ KM+ + +E + + K E E EN K G+ ++ + P SE
Sbjct: 40 SSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNEN-AKNGEAKITE---APASEK 95
Query: 70 EAKEGKSEREGESEMEGGSEREG------------KPEIEGKPESEGEPGSETR-AAGKR 116
E E K E ++ +GG ++E K + E + E +GE G E + G+
Sbjct: 96 EIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEE 155
Query: 117 PAEDDVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQK 175
++D K KG KE + D + E D K +DEK + +K
Sbjct: 156 DGKED-----KNGNEKGEDAKEKEDGKKGEDGKGNGE------DGKEKGEDEKEEEDRK 203
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 48.9 bits (115), Expect = 3e-06
Identities = 40/120 (33%), Positives = 62/120 (51%), Gaps = 9/120 (7%)
Query: 7 ENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPE 66
E EG A Q + E E P+ E + + +E + E E + E++G E + + +PE
Sbjct: 2089 EAEGEA--QPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEA--EGEAQPE 2144
Query: 67 SEG-EAKEGKSEREGESE--MEGGSEREGKPEIEG--KPESEGEPGSETRAAGKRPAEDD 121
SEG EA++ + E + ESE +E E +PE+EG PE+EGE E+ AE +
Sbjct: 2145 SEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGE 2204
Score = 46.6 bits (109), Expect = 2e-05
Identities = 43/125 (34%), Positives = 63/125 (50%), Gaps = 22/125 (17%)
Query: 7 ENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPE 66
E+EG+ + E E QP+ E +E ++ E E + E +G E + + +PE
Sbjct: 2144 ESEGVEAQDA--EGEAQPESEG-------IEAQEAEEEAQPELEGVEAPEA--EGEAQPE 2192
Query: 67 SEG-EAKEGKSEREGESEMEG----GSEREGKPEIEG--KPESEGE--PGSETRAAGKRP 117
SEG EA E +E E + E+EG +E E +PE EG PE+EGE P SE G++
Sbjct: 2193 SEGIEAPE--AEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKK 2250
Query: 118 AEDDV 122
V
Sbjct: 2251 GSPQV 2255
Score = 46.2 bits (108), Expect = 2e-05
Identities = 35/132 (26%), Positives = 63/132 (47%), Gaps = 15/132 (11%)
Query: 2 EKLYSENEGMASNQGKM------ENEEQPQDERKPEVTCTLEDKKLENEGKTENKG---- 51
E+ E EG + ++ E E QP+ E + +E ++ E E + E++
Sbjct: 1944 EEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAP 2003
Query: 52 -KTGDEEMLKDKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSET 110
G+ + +++ +PES+G + KSE E E+EG ++ K E + +PES+G E
Sbjct: 2004 EAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQ---KTEGDAQPESDGVEAPEA 2060
Query: 111 RAAGKRPAEDDV 122
+ AE +V
Sbjct: 2061 EEEAQE-AEGEV 2071
Score = 41.2 bits (95), Expect = 7e-04
Identities = 38/121 (31%), Positives = 52/121 (42%), Gaps = 8/121 (6%)
Query: 9 EGMASNQGKMENEEQPQ-DERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPES 67
E +G+ EE Q +E K E E +LE +TE +G+ +E L++ +
Sbjct: 1305 ETKEGTEGEGLQEEAVQLEETKTEEGLQEEGVQLEETKETEGEGQQEEEAQLEEIEETGG 1364
Query: 68 EGEAKEGKSEREGESEMEGGSEREGKPE---IEGKPESEGEPGSETRAA----GKRPAED 120
EG +EG E + EGG + E E EG PE G E A GK ED
Sbjct: 1365 EGLQEEGVQLEEVKEGPEGGLQGEALEEGLKEEGLPEEGSVHGQELSEASSPDGKGSQED 1424
Query: 121 D 121
D
Sbjct: 1425 D 1425
Score = 40.0 bits (92), Expect = 0.001
Identities = 41/149 (27%), Positives = 64/149 (42%), Gaps = 20/149 (13%)
Query: 6 SENEGMASNQG---KMENEEQPQDE-----RKPEVTCTLEDKKLENEGKTENKGKTGDEE 57
SE E +G K E + QP+ + E E + E EG+ + + D +
Sbjct: 2029 SEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQ 2088
Query: 58 MLKDKGKPESEG-EAKEGKSEREG-------ESEMEGGSEREG--KPEIEGK--PESEGE 105
+ + +PESEG EA E + E + E+E E E EG PE EG+ PESEG
Sbjct: 2089 EAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGV 2148
Query: 106 PGSETRAAGKRPAEDDVPRKAKRKTNKGL 134
+ + +E ++A+ + L
Sbjct: 2149 EAQDAEGEAQPESEGIEAQEAEEEAQPEL 2177
Score = 39.7 bits (91), Expect = 0.002
Identities = 34/131 (25%), Positives = 61/131 (46%), Gaps = 15/131 (11%)
Query: 7 ENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKL---ENEGKTENKGKTGDEEMLKDKG 63
E+E + + + + E + + +D PE ++ + E + E + +T E L+ +G
Sbjct: 1870 ESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEG 1929
Query: 64 K--PESEG----EAKEGKSEREGESEMEGG------SEREGKPEIEGKPESEGEPGSETR 111
+ PESEG EA+E E EG+++ E +E E +PE E E E ++
Sbjct: 1930 EDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEA 1989
Query: 112 AAGKRPAEDDV 122
+P +DV
Sbjct: 1990 EGEAQPESEDV 2000
Score = 38.5 bits (88), Expect = 0.004
Identities = 34/112 (30%), Positives = 52/112 (46%), Gaps = 11/112 (9%)
Query: 7 ENEGMASNQGKMENEEQPQ--DERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGK 64
E EG A Q ++E E P+ +E +PE +E + E E + E++G+T E+ KG
Sbjct: 2200 EAEGEA--QPELEGVEAPEAEEEAQPEPE-GVETPEAEGEAQPESEGETQGEK----KGS 2252
Query: 65 PESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKR 116
P+ +G+SE ES +R P G PGS+T + R
Sbjct: 2253 PQVS--LGDGQSEEASESSSPVPEDRPTPPPSPGGDTPHQRPGSQTGPSSSR 2302
Score = 37.7 bits (86), Expect = 0.007
Identities = 29/101 (28%), Positives = 47/101 (46%), Gaps = 14/101 (13%)
Query: 25 QDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPESEGEAKEGKSEREGESEM 84
QD + + +E + E E + E++G PE+EG+A+E + E + ESE
Sbjct: 1824 QDPGQSDGAEGIEAPEAEGEAQPESEGVEA----------PEAEGDAQEAEGEAQPESED 1873
Query: 85 EGGSEREGKPEIEGK----PESEGEPGSETRAAGKRPAEDD 121
E EG+ + E + PE+E E E+ A AE +
Sbjct: 1874 VEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKE 1914
Score = 35.8 bits (81), Expect = 0.028
Identities = 35/154 (22%), Positives = 61/154 (39%), Gaps = 18/154 (11%)
Query: 1 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLED-KKLENEGKTENKGKTGDEEML 59
+E+ EG + ++ EE +E E LE+ K+ E EG+ E + + + E
Sbjct: 1303 LEETKEGTEGEGLQEEAVQLEETKTEEGLQEEGVQLEETKETEGEGQQEEEAQLEEIEET 1362
Query: 60 KDKGKPESEGEAKEGKSEREGESE---MEGGSEREGKPEI--------------EGKPES 102
+G E + +E K EG + +E G + EG PE +GK
Sbjct: 1363 GGEGLQEEGVQLEEVKEGPEGGLQGEALEEGLKEEGLPEEGSVHGQELSEASSPDGKGSQ 1422
Query: 103 EGEPGSETRAAGKRPAEDDVPRKAKRKTNKGLAH 136
E +P E A + + P + + + +H
Sbjct: 1423 EDDPVQEEEAGRASASAEPCPAEGTEEPTEPPSH 1456
Score = 35.4 bits (80), Expect = 0.037
Identities = 33/123 (26%), Positives = 52/123 (42%), Gaps = 17/123 (13%)
Query: 6 SENEGMASN-QGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGK 64
+E + MA +GK N E E E + + G+T +G +G E+ L
Sbjct: 1763 AEGDAMAQEREGKTHNSETSAGSELGEAE--QEGEGISERGETGGQG-SGHEDNL----- 1814
Query: 65 PESEGEAKEGKSEREGESEMEGG-----SEREGKPEIEGKPESEGEPGSETRAAGKRPAE 119
+GEA G + G+S+ G +E E +PE EG E E ++ +P
Sbjct: 1815 ---QGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPES 1871
Query: 120 DDV 122
+DV
Sbjct: 1872 EDV 1874
Score = 35.4 bits (80), Expect = 0.037
Identities = 32/110 (29%), Positives = 56/110 (50%), Gaps = 10/110 (9%)
Query: 19 ENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPESEG-EAKEGKSE 77
E E++P+ E E+ E EG+T+ + + + + +++ +PESE EA E + E
Sbjct: 1928 EGEDEPESEGAEAQEA--EEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVE 1985
Query: 78 REGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAEDDVPRKAK 127
+ E EG ++ E + ++E PE+EGE A +P D V + K
Sbjct: 1986 TQ---EAEGEAQPESE-DVEA-PEAEGEMQEAEEEA--QPESDGVEAQPK 2028
Score = 32.0 bits (71), Expect = 0.41
Identities = 25/72 (34%), Positives = 34/72 (47%), Gaps = 5/72 (6%)
Query: 42 ENEGKTENKGKTGDEEMLKDKGKPESEGEAKEGKSEREGE---SEMEGGSEREGKPEIEG 98
+ G E + G + + +DK E E EREG+ SE GSE G+ E EG
Sbjct: 1736 QGPGVDEGEDGEGSQRLNRDKDPKLGEAEGDAMAQEREGKTHNSETSAGSEL-GEAEQEG 1794
Query: 99 KPESE-GEPGSE 109
+ SE GE G +
Sbjct: 1795 EGISERGETGGQ 1806
Score = 30.0 bits (66), Expect = 1.5
Identities = 22/91 (24%), Positives = 40/91 (43%)
Query: 19 ENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPESEGEAKEGKSER 78
E E +++R L + ++ E + E + + E L+++ E + +EG E
Sbjct: 1275 EAERDSEEQRASSNLEQLAENTVQEEVQLEETKEGTEGEGLQEEAVQLEETKTEEGLQEE 1334
Query: 79 EGESEMEGGSEREGKPEIEGKPESEGEPGSE 109
+ E +E EG+ E E + E E G E
Sbjct: 1335 GVQLEETKETEGEGQQEEEAQLEEIEETGGE 1365
>gi|157738619 smoothelin-like 1 [Homo sapiens]
Length = 512
Score = 48.5 bits (114), Expect = 4e-06
Identities = 35/117 (29%), Positives = 52/117 (44%), Gaps = 12/117 (10%)
Query: 4 LYSENEGMASNQGKMENEEQPQ--DERKPEVTCTLEDKKLEN----------EGKTENKG 51
L SE + + K E+ ++ D KPE T+E++ + E TE K
Sbjct: 150 LASEKQKAEEKEAKPESGQKADANDRDKPEPKATVEEEDAKTASQEETGQRKECSTEPKE 209
Query: 52 KTGDEEMLKDKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGS 108
K DEE + K E EAK E +G+ E + G++ E + E + E EPGS
Sbjct: 210 KATDEEAKAESQKAVVEDEAKAEPKEPDGKEEAKHGAKEEADAKEEAEDAEEAEPGS 266
Score = 33.5 bits (75), Expect = 0.14
Identities = 28/135 (20%), Positives = 57/135 (42%), Gaps = 2/135 (1%)
Query: 1 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKK-LENEGKTENKGKTGDEEML 59
++++ E++ A + E E + +D K E T ++ + E K+E K E L
Sbjct: 91 LDEVKVESQREAGGKEDAEAELKKEDGEKEETTVGSQEMTGRKEETKSEPKEAEEKESTL 150
Query: 60 KDKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAE 119
+ + E EAK ++ ++ + + E + K S+ E G + + P E
Sbjct: 151 ASEKQKAEEKEAKPESGQKADANDRDKPEPKATVEEEDAKTASQEETG-QRKECSTEPKE 209
Query: 120 DDVPRKAKRKTNKGL 134
+AK ++ K +
Sbjct: 210 KATDEEAKAESQKAV 224
Score = 30.4 bits (67), Expect = 1.2
Identities = 32/136 (23%), Positives = 51/136 (37%), Gaps = 22/136 (16%)
Query: 17 KMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPESEGE--AKEG 74
K +EE + +K V + + E +GK E K +E K++ + E E +
Sbjct: 210 KATDEEAKAESQKAVVEDEAKAEPKEPDGKEEAKHGAKEEADAKEEAEDAEEAEPGSPSE 269
Query: 75 KSEREGESEMEGG-----SEREGKPEIEGKPESEGE------------PGSETRAAGKRP 117
+ E++ E E EGG S E PE P EG +T +
Sbjct: 270 EQEQDVEKEPEGGAGVIPSSPEEWPE---SPTGEGHNLSTDGLGPDCVASGQTSPSASES 326
Query: 118 AEDDVPRKAKRKTNKG 133
+ DVP+ + G
Sbjct: 327 SPSDVPQSPPESPSSG 342
Score = 29.6 bits (65), Expect = 2.0
Identities = 38/159 (23%), Positives = 63/159 (39%), Gaps = 25/159 (15%)
Query: 7 ENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKT--ENKGKTGDE-------E 57
E++ A + KME +E E V+ ++ ++ G E KG G E
Sbjct: 8 ESDCSAEAREKMEQKEGKLSEDGTTVSPAADNPEMSGGGAPAEETKGTAGKAINEGPPTE 67
Query: 58 MLKDKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSE-------- 109
K + P +G + E + E G E++ S+RE GK ++E E E
Sbjct: 68 SGKQEKAPAEDGMSAELQGEANGLDEVKVESQREAG----GKEDAEAELKKEDGEKEETT 123
Query: 110 ---TRAAGKRPAEDDVPRKAKRKTNKGLAHYLK-EYKEA 144
G++ P++A+ K + + K E KEA
Sbjct: 124 VGSQEMTGRKEETKSEPKEAEEKESTLASEKQKAEEKEA 162
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 47.8 bits (112), Expect = 7e-06
Identities = 33/115 (28%), Positives = 57/115 (49%), Gaps = 4/115 (3%)
Query: 17 KMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPESEGEAKE--- 73
K+++EE+ + K E + +++ E TE + ++E +++GK E GE +E
Sbjct: 437 KVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEG 496
Query: 74 GKSEREGESEMEGGS-EREGKPEIEGKPESEGEPGSETRAAGKRPAEDDVPRKAK 127
G+ E + E S E+E K ++ + +S E S + K PAE P KAK
Sbjct: 497 GEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAK 551
Score = 44.7 bits (104), Expect = 6e-05
Identities = 39/162 (24%), Positives = 65/162 (40%), Gaps = 5/162 (3%)
Query: 18 MENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPESEGEAKEGKSE 77
++ EE+PQ+ + E E++K KTE K + EE K + E KE E
Sbjct: 824 VKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVE 883
Query: 78 REGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAEDDVPRKAKRKTNKGLAHY 137
+ ES++E E + PE E E + K + +V +K
Sbjct: 884 KPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSK 943
Query: 138 LKEYKEAIHDMNFSNEDMIREFDNMAKV-----QDEKRKSKQ 174
E KEA + + E+ ++ + K +D+K SK+
Sbjct: 944 PAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKE 985
Score = 42.0 bits (97), Expect = 4e-04
Identities = 30/114 (26%), Positives = 50/114 (43%), Gaps = 5/114 (4%)
Query: 19 ENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPESEGEAKEGKSER 78
E + P + + PE + E K+ + K+ ++E K + +S +AK E
Sbjct: 536 EEAKSPAEVKSPEKA----KSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKE- 590
Query: 79 EGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAEDDVPRKAKRKTNK 132
E +S E S + K ++ + +S E S + K PAE P KAK T +
Sbjct: 591 EAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKE 644
Score = 36.2 bits (82), Expect = 0.022
Identities = 22/77 (28%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
Query: 15 QGKMENEEQPQDERKPEVTCTLEDK--KLENEGKTENKGKTGDEEMLKDKGKPESEGEAK 72
+ K ++ + E PE T E+K K E + KTE K K D+ + K+ KP++E K
Sbjct: 937 KAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEK 996
Query: 73 EGKSEREGESEMEGGSE 89
++++ E +E
Sbjct: 997 SSSTDQKDSKPPEKATE 1013
Score = 33.9 bits (76), Expect = 0.11
Identities = 30/124 (24%), Positives = 54/124 (43%), Gaps = 7/124 (5%)
Query: 19 ENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPESEGEAKEGKSER 78
E + P + + P E+ K E K+ K K+ +E K K +S E +E KS
Sbjct: 610 EEAKSPAEAKSP----VKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSP-EKEEAKSPE 664
Query: 79 EGESEM--EGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAEDDVPRKAKRKTNKGLAH 136
+ +S + E S + K ++ + +S + S + K P + P K + K+ +
Sbjct: 665 KAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKS 724
Query: 137 YLKE 140
+KE
Sbjct: 725 PVKE 728
Score = 32.7 bits (73), Expect = 0.24
Identities = 28/121 (23%), Positives = 52/121 (42%), Gaps = 11/121 (9%)
Query: 7 ENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPE 66
E++ A + + ++ P E++ +++ E KTE K D+ K+ KP
Sbjct: 887 ESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKE-KTEVAKKEPDDAKAKEPSKP- 944
Query: 67 SEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAEDDVPRKA 126
E KE E++ E E+ KPE KP++E + + + K P++ +
Sbjct: 945 --AEKKEAAPEKKDTKE-----EKAKKPE--EKPKTEAKAKEDDKTLSKEPSKPKAEKAE 995
Query: 127 K 127
K
Sbjct: 996 K 996
Score = 32.3 bits (72), Expect = 0.31
Identities = 26/105 (24%), Positives = 41/105 (39%), Gaps = 8/105 (7%)
Query: 17 KMENEEQPQDERKPEVTCTLED--------KKLENEGKTENKGKTGDEEMLKDKGKPESE 68
K+E +E + + K EV D K E + K T +E+ K + KP++E
Sbjct: 913 KVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTE 972
Query: 69 GEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAA 113
+AKE E + E + K E +E +AA
Sbjct: 973 AKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAA 1017
Score = 31.2 bits (69), Expect = 0.70
Identities = 32/160 (20%), Positives = 64/160 (40%), Gaps = 4/160 (2%)
Query: 19 ENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPESEGEAKEGKSER 78
E + P+ + PE TL+ K E + + + ++ + +K K + E K + +
Sbjct: 742 EEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARS-PADKFPEKAKSPVKEEVKSPEKAK 800
Query: 79 EGESEMEGGSERE--GKPEIEGKPESEGEPGS-ETRAAGKRPAEDDVPRKAKRKTNKGLA 135
E E+E K E++ + E +P + + K+ E+ P K + K
Sbjct: 801 SPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSK 860
Query: 136 HYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQK 175
KEA ++ E +KV+ +K +++ K
Sbjct: 861 KEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDK 900
Score = 29.3 bits (64), Expect = 2.6
Identities = 29/116 (25%), Positives = 53/116 (45%), Gaps = 11/116 (9%)
Query: 19 ENEEQPQDERKP--EVTCTLEDKK--LENEGKTENKGKTGDEEMLKDKGKPESEGEAKEG 74
E + P+ + P E T E K ++ E K+ K K+ ++ D PE++ AKE
Sbjct: 714 EEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKE- 772
Query: 75 KSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAEDDVPRKAKRKT 130
E S + E+ P ++ + +S + S + K P E ++P+K + K+
Sbjct: 773 ----EARSPADKFPEKAKSP-VKEEVKSPEKAKSPLKEDAKAP-EKEIPKKEEVKS 822
>gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 47.4 bits (111), Expect = 9e-06
Identities = 48/159 (30%), Positives = 65/159 (40%), Gaps = 31/159 (19%)
Query: 22 EQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPESEGEAKEGKSEREGE 81
E+P DE+K E T ED EG +EN K E ++G PE E E EG +R E
Sbjct: 423 EEPIDEKKFEKT---EDGGEFEEGASENNAKESSPEKEAEEGCPEKESE--EGCPKRGFE 477
Query: 82 SEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAEDDVPRK-AKRKTNKGLAHYLKE 140
EG P R +E+D P+K +K+KT K
Sbjct: 478 GSCSQKESEEGNP--------------------VRGSEEDSPKKESKKKTLKNDCEENGL 517
Query: 141 YKEAIHDMNFSNEDMI-----REFDNMAKVQDEKRKSKQ 174
KE+ D+N +E+ + E D+ K DE KQ
Sbjct: 518 AKESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQ 556
Score = 38.1 bits (87), Expect = 0.006
Identities = 46/173 (26%), Positives = 76/173 (43%), Gaps = 18/173 (10%)
Query: 6 SENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLE-NEGKTENKGKTGDEEMLKDKGK 64
SE E + K +EE + E V DK+LE N+ + G E++L ++G
Sbjct: 561 SEREFEENGLEKDLDEEGSEKELHENVL----DKELEENDSENSEFEDDGSEKVLDEEG- 615
Query: 65 PESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAEDDVPR 124
SE E E E+E E E E+ E + K + E AA K+ E D
Sbjct: 616 --SEREFDEDSDEKE---EEEDTYEKVFDDESDEKEDEEYADEKGLEAADKKAEEGDADE 670
Query: 125 KAKRKTNKGLAHYLKEYKEAI-HDMNFSNEDMIREFDNMAKVQDEKRKSKQKL 176
K +++ KE ++A ++ ++E + + D+ K+ DE+ S +KL
Sbjct: 671 KLFEESDD------KEDEDADGKEVEDADEKLFEDDDSNEKLFDEEEDSSEKL 717
Score = 36.2 bits (82), Expect = 0.022
Identities = 48/197 (24%), Positives = 74/197 (37%), Gaps = 30/197 (15%)
Query: 9 EGMASNQGKMENEEQPQDERKPEVTCT-------LEDKKLENEGKTENKGKTGDEEMLKD 61
EG + N K + E+ +E PE E + E + N + +E+ K
Sbjct: 442 EGASENNAKESSPEKEAEEGCPEKESEEGCPKRGFEGSCSQKESEEGNPVRGSEEDSPKK 501
Query: 62 KGKP-------ESEGEAKEGKSEREGESEMEGGSEREG------KPEIEGKPESEGEPGS 108
+ K E G AKE + + ESE E G +E K E E + E GS
Sbjct: 502 ESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGS 561
Query: 109 ETRAAGKRPAEDDVPRKAKRK------TNKGLAHYLKEYKEAIHDMN---FSNEDMIREF 159
E R + E D+ + K +K L E E D + E REF
Sbjct: 562 E-REFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREF 620
Query: 160 DNMAKVQDEKRKSKQKL 176
D + ++E+ + +K+
Sbjct: 621 DEDSDEKEEEEDTYEKV 637
>gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 47.4 bits (111), Expect = 9e-06
Identities = 48/159 (30%), Positives = 65/159 (40%), Gaps = 31/159 (19%)
Query: 22 EQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPESEGEAKEGKSEREGE 81
E+P DE+K E T ED EG +EN K E ++G PE E E EG +R E
Sbjct: 423 EEPIDEKKFEKT---EDGGEFEEGASENNAKESSPEKEAEEGCPEKESE--EGCPKRGFE 477
Query: 82 SEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAEDDVPRK-AKRKTNKGLAHYLKE 140
EG P R +E+D P+K +K+KT K
Sbjct: 478 GSCSQKESEEGNP--------------------VRGSEEDSPKKESKKKTLKNDCEENGL 517
Query: 141 YKEAIHDMNFSNEDMI-----REFDNMAKVQDEKRKSKQ 174
KE+ D+N +E+ + E D+ K DE KQ
Sbjct: 518 AKESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQ 556
Score = 38.1 bits (87), Expect = 0.006
Identities = 46/173 (26%), Positives = 76/173 (43%), Gaps = 18/173 (10%)
Query: 6 SENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLE-NEGKTENKGKTGDEEMLKDKGK 64
SE E + K +EE + E V DK+LE N+ + G E++L ++G
Sbjct: 561 SEREFEENGLEKDLDEEGSEKELHENVL----DKELEENDSENSEFEDDGSEKVLDEEG- 615
Query: 65 PESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAEDDVPR 124
SE E E E+E E E E+ E + K + E AA K+ E D
Sbjct: 616 --SEREFDEDSDEKE---EEEDTYEKVFDDESDEKEDEEYADEKGLEAADKKAEEGDADE 670
Query: 125 KAKRKTNKGLAHYLKEYKEAI-HDMNFSNEDMIREFDNMAKVQDEKRKSKQKL 176
K +++ KE ++A ++ ++E + + D+ K+ DE+ S +KL
Sbjct: 671 KLFEESDD------KEDEDADGKEVEDADEKLFEDDDSNEKLFDEEEDSSEKL 717
Score = 36.2 bits (82), Expect = 0.022
Identities = 48/197 (24%), Positives = 74/197 (37%), Gaps = 30/197 (15%)
Query: 9 EGMASNQGKMENEEQPQDERKPEVTCT-------LEDKKLENEGKTENKGKTGDEEMLKD 61
EG + N K + E+ +E PE E + E + N + +E+ K
Sbjct: 442 EGASENNAKESSPEKEAEEGCPEKESEEGCPKRGFEGSCSQKESEEGNPVRGSEEDSPKK 501
Query: 62 KGKP-------ESEGEAKEGKSEREGESEMEGGSEREG------KPEIEGKPESEGEPGS 108
+ K E G AKE + + ESE E G +E K E E + E GS
Sbjct: 502 ESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGS 561
Query: 109 ETRAAGKRPAEDDVPRKAKRK------TNKGLAHYLKEYKEAIHDMN---FSNEDMIREF 159
E R + E D+ + K +K L E E D + E REF
Sbjct: 562 E-REFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREF 620
Query: 160 DNMAKVQDEKRKSKQKL 176
D + ++E+ + +K+
Sbjct: 621 DEDSDEKEEEEDTYEKV 637
>gi|4557509 cylicin 2 [Homo sapiens]
Length = 348
Score = 47.4 bits (111), Expect = 9e-06
Identities = 48/204 (23%), Positives = 91/204 (44%), Gaps = 40/204 (19%)
Query: 2 EKLYSENEGMASNQGKMENEE------QPQDERKPEVTCTLEDKKLENEGK---TENKGK 52
EKL ++ + S +GK + E+ + +DE+ +DKK N+GK TE++G+
Sbjct: 153 EKLDAKKD---SKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGE 209
Query: 53 TGDEEMLKDKGKPES----------EGEAKEGKSEREGESEMEGGSE-----------RE 91
G E KGK +S + + K + +G+ + G E ++
Sbjct: 210 KGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKK 269
Query: 92 GKPEIEGKPESEGEPGSETRAAGKRPAEDDVPRKAKRKTNKGLAHYLKEYKEAIHDMNFS 151
GK + + ++ + + + K+ A D + AK+ T K A K+ K+ +
Sbjct: 270 GKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKN------A 323
Query: 152 NEDMIREFDNMAKVQDEKRKSKQK 175
+D ++ AK +DEK+ +K+K
Sbjct: 324 KKDAKKDAKKNAK-KDEKKDAKKK 346
Score = 44.7 bits (104), Expect = 6e-05
Identities = 35/168 (20%), Positives = 79/168 (47%), Gaps = 7/168 (4%)
Query: 7 ENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPE 66
E + A+ GK ++ Q + + + KK +GK KGK +E++ K +
Sbjct: 106 EVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGK--EEKLDAKKDSKK 163
Query: 67 SEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAEDDVPRKA 126
+ +A++GK + +GG++++ K + K +S S T + G++ + +K
Sbjct: 164 GKKDAEKGKDSATESEDEKGGAKKDNKKD---KKDSNKGKDSATESEGEKGGTEKDSKKG 220
Query: 127 KRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQ 174
K+ + KG ++ +A+ +ED ++ + + +D K+ +K+
Sbjct: 221 KKDSKKGKDSAIE--LQAVKADEKKDEDGKKDANKGDESKDAKKDAKE 266
Score = 40.4 bits (93), Expect = 0.001
Identities = 26/98 (26%), Positives = 49/98 (50%), Gaps = 4/98 (4%)
Query: 39 KKLENEGKTENKGKTGDEEMLKDKGKPESEGEAKEGKSEREGESEMEGGSERE---GKPE 95
+ +E + K GK G+++ + K +SE E K+GK + + ++E G E + K
Sbjct: 103 RTVEVDSKAAEIGKKGEDKTTQ-KDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDS 161
Query: 96 IEGKPESEGEPGSETRAAGKRPAEDDVPRKAKRKTNKG 133
+GK ++E S T + ++ +K K+ +NKG
Sbjct: 162 KKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKG 199
>gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens]
Length = 569
Score = 47.0 bits (110), Expect = 1e-05
Identities = 31/108 (28%), Positives = 59/108 (54%), Gaps = 3/108 (2%)
Query: 2 EKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKD 61
E+ YSE+E + + ++ +++Q + R + E ++ E + + E K K EE ++
Sbjct: 341 EEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMK-EKEEEEMKKEEEMKKKEEKEEEEEE 399
Query: 62 KGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSE 109
+ K + E E K+E EGES+ E + +G + EG+P+ +PG+E
Sbjct: 400 EMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQ--DPGTE 445
Score = 45.1 bits (105), Expect = 5e-05
Identities = 33/108 (30%), Positives = 59/108 (54%), Gaps = 10/108 (9%)
Query: 3 KLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDK 62
+L+S+++ + E +E+ ++E K E +++K E E + E K K +EE+ +
Sbjct: 356 RLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEK-EEEEEEEMKQKEEEEEI---R 411
Query: 63 GKPESEGEAKEGKSEREGESEMEGGSEREGKPEIE-GKPESEGEPGSE 109
K E EGE+K+ + E E +GG + EG+P+ + G E+ GE E
Sbjct: 412 NKNEEEGESKDEEDEDE-----DGGQKPEGEPQQDPGTEETYGEVEEE 454
Score = 42.0 bits (97), Expect = 4e-04
Identities = 26/90 (28%), Positives = 42/90 (46%)
Query: 20 NEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPESEGEAKEGKSERE 79
NEE+ +DE E ++ K + K ++ +K+K + E + E + K E +
Sbjct: 334 NEEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEK 393
Query: 80 GESEMEGGSEREGKPEIEGKPESEGEPGSE 109
E E E ++E + EI K E EGE E
Sbjct: 394 EEEEEEEMKQKEEEEEIRNKNEEEGESKDE 423
Score = 32.0 bits (71), Expect = 0.41
Identities = 31/180 (17%), Positives = 74/180 (41%), Gaps = 15/180 (8%)
Query: 2 EKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEE---- 57
+++ + E + +M+ +E+ ++E + E+ E++++ N+ + E + K ++E
Sbjct: 371 QEMKEKEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDG 430
Query: 58 -------MLKDKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSET 110
+D G E+ GE +E + + +++ E E P P S
Sbjct: 431 GQKPEGEPQQDPGTEETYGEVEEEPLDEAQDDDLDELMEME--PTFVHASSQTSGPTSGY 488
Query: 111 RAAGKRPAEDDVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKR 170
A A + + ++R+ + L E + +S+ +IR + + Q +R
Sbjct: 489 HAENFLGASPPIIQPSRRRNQNRVP--LLEGLPGTNSPFYSSPQLIRRTGRLGQRQVRRR 546
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.304 0.128 0.359
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,973,507
Number of Sequences: 37866
Number of extensions: 549317
Number of successful extensions: 8387
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 343
Number of HSP's successfully gapped in prelim test: 591
Number of HSP's that attempted gapping in prelim test: 3174
Number of HSP's gapped (non-prelim): 3755
length of query: 215
length of database: 18,247,518
effective HSP length: 98
effective length of query: 117
effective length of database: 14,536,650
effective search space: 1700788050
effective search space used: 1700788050
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.