Guide to the Human Genome
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Search of human proteins with 4885413

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4885413 histidine triad nucleotide binding protein 1 [Homo
sapiens]
         (126 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4885413 histidine triad nucleotide binding protein 1 [Homo sa...   262   6e-71
gi|14211923 PKCI-1-related HIT protein [Homo sapiens]                 164   2e-41
gi|189217863 histidine triad nucleotide binding protein 3 [Homo ...    49   1e-06
gi|28329436 aprataxin isoform a [Homo sapiens]                         47   4e-06
gi|28329433 aprataxin isoform c [Homo sapiens]                         47   4e-06
gi|28329430 aprataxin isoform b [Homo sapiens]                         47   4e-06
gi|28329427 aprataxin isoform d [Homo sapiens]                         46   7e-06
gi|8923156 aprataxin isoform d [Homo sapiens]                          46   7e-06
gi|122937239 zinc finger CCCH-type domain containing 5 [Homo sap...    36   0.009
gi|4503719 fragile histidine triad gene [Homo sapiens]                 33   0.044

>gi|4885413 histidine triad nucleotide binding protein 1 [Homo
           sapiens]
          Length = 126

 Score =  262 bits (669), Expect = 6e-71
 Identities = 126/126 (100%), Positives = 126/126 (100%)

Query: 1   MADEIAKAQVARPGGDTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHI 60
           MADEIAKAQVARPGGDTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHI
Sbjct: 1   MADEIAKAQVARPGGDTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHI 60

Query: 61  SQISVAEDDDESLLGHLMIVGKKCAADLGLNKGYRMVVNEGSDGGQSVYHVHLHVLGGRQ 120
           SQISVAEDDDESLLGHLMIVGKKCAADLGLNKGYRMVVNEGSDGGQSVYHVHLHVLGGRQ
Sbjct: 61  SQISVAEDDDESLLGHLMIVGKKCAADLGLNKGYRMVVNEGSDGGQSVYHVHLHVLGGRQ 120

Query: 121 MHWPPG 126
           MHWPPG
Sbjct: 121 MHWPPG 126


>gi|14211923 PKCI-1-related HIT protein [Homo sapiens]
          Length = 163

 Score =  164 bits (415), Expect = 2e-41
 Identities = 75/126 (59%), Positives = 98/126 (77%), Gaps = 2/126 (1%)

Query: 3   DEIAKAQVARPGG--DTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHI 60
           +E+AKAQ A PGG   TIF +I+ K +PA I++ED +CL F D++PQAP HFLVIPKK I
Sbjct: 38  NEVAKAQQATPGGAAPTIFSRILDKSLPADILYEDQQCLVFRDVAPQAPVHFLVIPKKPI 97

Query: 61  SQISVAEDDDESLLGHLMIVGKKCAADLGLNKGYRMVVNEGSDGGQSVYHVHLHVLGGRQ 120
            +IS AE++D+ LLGHL++V K+ A   GL  GYR+V+N+G  G QSVYH+H+HVLGGRQ
Sbjct: 98  PRISQAEEEDQQLLGHLLLVAKQTAKAEGLGDGYRLVINDGKLGAQSVYHLHIHVLGGRQ 157

Query: 121 MHWPPG 126
           + WPPG
Sbjct: 158 LQWPPG 163


>gi|189217863 histidine triad nucleotide binding protein 3 [Homo
           sapiens]
          Length = 182

 Score = 48.5 bits (114), Expect = 1e-06
 Identities = 29/101 (28%), Positives = 47/101 (46%), Gaps = 2/101 (1%)

Query: 18  IFGKIIRKEIPAKIIF--EDDRCLAFHDISPQAPTHFLVIPKKHISQISVAEDDDESLLG 75
           +F +I  ++ P   +   E++  + F DI P A  H+LV+PKKHI        D   L+ 
Sbjct: 49  VFCRIAGRQDPGTELLHCENEDLICFKDIKPAATHHYLVVPKKHIGNCRTLRKDQVELVE 108

Query: 76  HLMIVGKKCAADLGLNKGYRMVVNEGSDGGQSVYHVHLHVL 116
           +++ VGK             + +        S+ H+HLHVL
Sbjct: 109 NMVTVGKTILERNNFTDFTNVRMGFHMPPFCSISHLHLHVL 149


>gi|28329436 aprataxin isoform a [Homo sapiens]
          Length = 342

 Score = 47.0 bits (110), Expect = 4e-06
 Identities = 29/97 (29%), Positives = 47/97 (48%), Gaps = 2/97 (2%)

Query: 20  GKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVAEDDDESLLGHLMI 79
           G  I  + P   +++D++ +   D  P+A  H+LV+P   IS +     +   LL H+  
Sbjct: 170 GLKISMQDPKMQVYKDEQVVVIKDKYPKARYHWLVLPWTSISSLKAVAREHLELLKHMHT 229

Query: 80  VGKKCAADLGLNKGYRMVVNEGSDGGQSVYHVHLHVL 116
           VG+K   D   +   R  +  G     S+ HVHLHV+
Sbjct: 230 VGEKVIVDFAGSSKLRFRL--GYHAIPSMSHVHLHVI 264


>gi|28329433 aprataxin isoform c [Homo sapiens]
          Length = 254

 Score = 47.0 bits (110), Expect = 4e-06
 Identities = 29/97 (29%), Positives = 47/97 (48%), Gaps = 2/97 (2%)

Query: 20  GKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVAEDDDESLLGHLMI 79
           G  I  + P   +++D++ +   D  P+A  H+LV+P   IS +     +   LL H+  
Sbjct: 82  GLKISMQDPKMQVYKDEQVVVIKDKYPKARYHWLVLPWTSISSLKAVAREHLELLKHMHT 141

Query: 80  VGKKCAADLGLNKGYRMVVNEGSDGGQSVYHVHLHVL 116
           VG+K   D   +   R  +  G     S+ HVHLHV+
Sbjct: 142 VGEKVIVDFAGSSKLRFRL--GYHAIPSMSHVHLHVI 176


>gi|28329430 aprataxin isoform b [Homo sapiens]
          Length = 306

 Score = 47.0 bits (110), Expect = 4e-06
 Identities = 29/97 (29%), Positives = 47/97 (48%), Gaps = 2/97 (2%)

Query: 20  GKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVAEDDDESLLGHLMI 79
           G  I  + P   +++D++ +   D  P+A  H+LV+P   IS +     +   LL H+  
Sbjct: 184 GLKISMQDPKMQVYKDEQVVVIKDKYPKARYHWLVLPWTSISSLKAVAREHLELLKHMHT 243

Query: 80  VGKKCAADLGLNKGYRMVVNEGSDGGQSVYHVHLHVL 116
           VG+K   D   +   R  +  G     S+ HVHLHV+
Sbjct: 244 VGEKVIVDFAGSSKLRFRL--GYHAIPSMSHVHLHVI 278


>gi|28329427 aprataxin isoform d [Homo sapiens]
          Length = 168

 Score = 46.2 bits (108), Expect = 7e-06
 Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 2/89 (2%)

Query: 28  PAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVAEDDDESLLGHLMIVGKKCAAD 87
           P   +++D++ +   D  P+A  H+LV+P   IS +     +   LL H+  VG+K   D
Sbjct: 4   PKMQVYKDEQVVVIKDKYPKARYHWLVLPWTSISSLKAVAREHLELLKHMHTVGEKVIVD 63

Query: 88  LGLNKGYRMVVNEGSDGGQSVYHVHLHVL 116
              +   R  +  G     S+ HVHLHV+
Sbjct: 64  FAGSSKLRFRL--GYHAIPSMSHVHLHVI 90


>gi|8923156 aprataxin isoform d [Homo sapiens]
          Length = 168

 Score = 46.2 bits (108), Expect = 7e-06
 Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 2/89 (2%)

Query: 28  PAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVAEDDDESLLGHLMIVGKKCAAD 87
           P   +++D++ +   D  P+A  H+LV+P   IS +     +   LL H+  VG+K   D
Sbjct: 4   PKMQVYKDEQVVVIKDKYPKARYHWLVLPWTSISSLKAVAREHLELLKHMHTVGEKVIVD 63

Query: 88  LGLNKGYRMVVNEGSDGGQSVYHVHLHVL 116
              +   R  +  G     S+ HVHLHV+
Sbjct: 64  FAGSSKLRFRL--GYHAIPSMSHVHLHVI 90


>gi|122937239 zinc finger CCCH-type domain containing 5 [Homo
           sapiens]
          Length = 886

 Score = 35.8 bits (81), Expect = 0.009
 Identities = 20/57 (35%), Positives = 27/57 (47%), Gaps = 4/57 (7%)

Query: 10  VARPGGDTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAP----THFLVIPKKHISQ 62
           V  PG  TI G +++   P  I        +FH  SP  P    +HFL  P+ H+SQ
Sbjct: 617 VPHPGSITIGGSLLQSSAPVNIPGSLGSSASFHSASPSPPVSLSSHFLQQPQGHLSQ 673


>gi|4503719 fragile histidine triad gene [Homo sapiens]
          Length = 147

 Score = 33.5 bits (75), Expect = 0.044
 Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 6/100 (6%)

Query: 19  FGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQI-SVAEDDDESLLGHL 77
           FG+ + K  P+ +  + +   A  +  P  P H LV P + + +   +  D+   L    
Sbjct: 5   FGQHLIK--PSVVFLKTELSFALVNRKPVVPGHVLVCPLRPVERFHDLRPDEVADLFQTT 62

Query: 78  MIVGKKCAADL-GLNKGYRMVVNEGSDGGQSVYHVHLHVL 116
             VG        G +  + M   +G + GQ+V HVH+HVL
Sbjct: 63  QRVGTVVEKHFHGTSLTFSM--QDGPEAGQTVKHVHVHVL 100


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.140    0.431 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,370,811
Number of Sequences: 37866
Number of extensions: 219521
Number of successful extensions: 341
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 324
Number of HSP's gapped (non-prelim): 10
length of query: 126
length of database: 18,247,518
effective HSP length: 90
effective length of query: 36
effective length of database: 14,839,578
effective search space: 534224808
effective search space used: 534224808
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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