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Search of human proteins with 48255949
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo
sapiens]
(1198 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sap... 2378 0.0
gi|48255951 plasma membrane calcium ATPase 2 isoform 1 [Homo sap... 2357 0.0
gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo sa... 2003 0.0
gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo sa... 1977 0.0
gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo sa... 1878 0.0
gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo sa... 1818 0.0
gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo sa... 1769 0.0
gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo sa... 1712 0.0
gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [H... 303 6e-82
gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1 [... 303 6e-82
gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b [... 299 9e-81
gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a [... 299 9e-81
gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Hom... 297 4e-80
gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Hom... 297 4e-80
gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Hom... 297 4e-80
gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Hom... 297 4e-80
gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Hom... 297 4e-80
gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Hom... 297 4e-80
gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Hom... 297 4e-80
gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sap... 293 5e-79
gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo sap... 293 5e-79
gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo sap... 293 5e-79
gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo sap... 290 4e-78
gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo ... 283 9e-76
gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens] 278 3e-74
gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3 ... 276 1e-73
gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo sapi... 273 9e-73
gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo sapi... 273 9e-73
gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens] 273 9e-73
gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens] 271 2e-72
>gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sapiens]
Length = 1198
Score = 2378 bits (6163), Expect = 0.0
Identities = 1198/1198 (100%), Positives = 1198/1198 (100%)
Query: 1 MGDMTNSDFYSKNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAICRRL 60
MGDMTNSDFYSKNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAICRRL
Sbjct: 1 MGDMTNSDFYSKNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAICRRL 60
Query: 61 KTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLG 120
KTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLG
Sbjct: 61 KTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLG 120
Query: 121 LSFYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFR 180
LSFYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFR
Sbjct: 121 LSFYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFR 180
Query: 181 GLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESS 240
GLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESS
Sbjct: 181 GLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESS 240
Query: 241 LTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKD 300
LTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKD
Sbjct: 241 LTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKD 300
Query: 301 KKAKQQDGAAAMEMQPLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMS 360
KKAKQQDGAAAMEMQPLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMS
Sbjct: 301 KKAKQQDGAAAMEMQPLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMS 360
Query: 361 AITVIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTI 420
AITVIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTI
Sbjct: 361 AITVIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTI 420
Query: 421 SLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIP 480
SLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIP
Sbjct: 421 SLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIP 480
Query: 481 DPSSINTKTMELLINAIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDLKQDYE 540
DPSSINTKTMELLINAIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDLKQDYE
Sbjct: 481 DPSSINTKTMELLINAIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDLKQDYE 540
Query: 541 PVRSQMPEEKLYKVYTFNSVRKSMSTVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEP 600
PVRSQMPEEKLYKVYTFNSVRKSMSTVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEP
Sbjct: 541 PVRSQMPEEKLYKVYTFNSVRKSMSTVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEP 600
Query: 601 RVFRPRDRDEMVKKVIEPMACDGLRTICVAYRDFPSSPEPDWDNENDILNELTCICVVGI 660
RVFRPRDRDEMVKKVIEPMACDGLRTICVAYRDFPSSPEPDWDNENDILNELTCICVVGI
Sbjct: 601 RVFRPRDRDEMVKKVIEPMACDGLRTICVAYRDFPSSPEPDWDNENDILNELTCICVVGI 660
Query: 661 EDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRR 720
EDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRR
Sbjct: 661 EDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRR 720
Query: 721 IRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDG 780
IRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDG
Sbjct: 721 IRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDG 780
Query: 781 PALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTV 840
PALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTV
Sbjct: 781 PALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTV 840
Query: 841 NVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKP 900
NVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKP
Sbjct: 841 NVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKP 900
Query: 901 LISRTMMKNILGHAVYQLALIFTLLFVGEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMM 960
LISRTMMKNILGHAVYQLALIFTLLFVGEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMM
Sbjct: 901 LISRTMMKNILGHAVYQLALIFTLLFVGEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMM 960
Query: 961 QLFNEINARKIHGERNVFDGIFRNPIFCTIVLGTFAIQIVIVQFGGKPFSCSPLQLDQWM 1020
QLFNEINARKIHGERNVFDGIFRNPIFCTIVLGTFAIQIVIVQFGGKPFSCSPLQLDQWM
Sbjct: 961 QLFNEINARKIHGERNVFDGIFRNPIFCTIVLGTFAIQIVIVQFGGKPFSCSPLQLDQWM 1020
Query: 1021 WCIFIGLGELVWGQVIATIPTSRLKFLKEAGRLTQKEEIPEEELNEDVEEIDHAERELRR 1080
WCIFIGLGELVWGQVIATIPTSRLKFLKEAGRLTQKEEIPEEELNEDVEEIDHAERELRR
Sbjct: 1021 WCIFIGLGELVWGQVIATIPTSRLKFLKEAGRLTQKEEIPEEELNEDVEEIDHAERELRR 1080
Query: 1081 GQILWFRGLNRIQTQIRVVKAFRSSLYEGLEKPESRTSIHNFMAHPEFRIEDSQPHIPLI 1140
GQILWFRGLNRIQTQIRVVKAFRSSLYEGLEKPESRTSIHNFMAHPEFRIEDSQPHIPLI
Sbjct: 1081 GQILWFRGLNRIQTQIRVVKAFRSSLYEGLEKPESRTSIHNFMAHPEFRIEDSQPHIPLI 1140
Query: 1141 DDTDLEEDAALKQNSSPPSSLNKNNSAIDSGINLTTDTSKSATSSSPGSPIHSLETSL 1198
DDTDLEEDAALKQNSSPPSSLNKNNSAIDSGINLTTDTSKSATSSSPGSPIHSLETSL
Sbjct: 1141 DDTDLEEDAALKQNSSPPSSLNKNNSAIDSGINLTTDTSKSATSSSPGSPIHSLETSL 1198
>gi|48255951 plasma membrane calcium ATPase 2 isoform 1 [Homo sapiens]
Length = 1243
Score = 2357 bits (6107), Expect = 0.0
Identities = 1198/1243 (96%), Positives = 1198/1243 (96%), Gaps = 45/1243 (3%)
Query: 1 MGDMTNSDFYSKNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAICRRL 60
MGDMTNSDFYSKNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAICRRL
Sbjct: 1 MGDMTNSDFYSKNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAICRRL 60
Query: 61 KTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLG 120
KTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLG
Sbjct: 61 KTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLG 120
Query: 121 LSFYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFR 180
LSFYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFR
Sbjct: 121 LSFYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFR 180
Query: 181 GLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESS 240
GLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESS
Sbjct: 181 GLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESS 240
Query: 241 LTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKD 300
LTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKD
Sbjct: 241 LTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKD 300
Query: 301 KK---------------------------------------------AKQQDGAAAMEMQ 315
KK AKQQDGAAAMEMQ
Sbjct: 301 KKGVKKGDGLQLPAADGAAASNAADSANASLVNGKMQDGNVDASQSKAKQQDGAAAMEMQ 360
Query: 316 PLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDT 375
PLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDT
Sbjct: 361 PLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDT 420
Query: 376 FVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNL 435
FVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNL
Sbjct: 421 FVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNL 480
Query: 436 VRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIPDPSSINTKTMELLIN 495
VRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIPDPSSINTKTMELLIN
Sbjct: 481 VRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIPDPSSINTKTMELLIN 540
Query: 496 AIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKVY 555
AIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKVY
Sbjct: 541 AIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKVY 600
Query: 556 TFNSVRKSMSTVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKV 615
TFNSVRKSMSTVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKV
Sbjct: 601 TFNSVRKSMSTVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKV 660
Query: 616 IEPMACDGLRTICVAYRDFPSSPEPDWDNENDILNELTCICVVGIEDPVRPEVPEAIRKC 675
IEPMACDGLRTICVAYRDFPSSPEPDWDNENDILNELTCICVVGIEDPVRPEVPEAIRKC
Sbjct: 661 IEPMACDGLRTICVAYRDFPSSPEPDWDNENDILNELTCICVVGIEDPVRPEVPEAIRKC 720
Query: 676 QRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDK 735
QRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDK
Sbjct: 721 QRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDK 780
Query: 736 IWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIA 795
IWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIA
Sbjct: 781 IWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIA 840
Query: 796 GTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACIT 855
GTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACIT
Sbjct: 841 GTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACIT 900
Query: 856 QDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAV 915
QDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAV
Sbjct: 901 QDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAV 960
Query: 916 YQLALIFTLLFVGEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARKIHGER 975
YQLALIFTLLFVGEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARKIHGER
Sbjct: 961 YQLALIFTLLFVGEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARKIHGER 1020
Query: 976 NVFDGIFRNPIFCTIVLGTFAIQIVIVQFGGKPFSCSPLQLDQWMWCIFIGLGELVWGQV 1035
NVFDGIFRNPIFCTIVLGTFAIQIVIVQFGGKPFSCSPLQLDQWMWCIFIGLGELVWGQV
Sbjct: 1021 NVFDGIFRNPIFCTIVLGTFAIQIVIVQFGGKPFSCSPLQLDQWMWCIFIGLGELVWGQV 1080
Query: 1036 IATIPTSRLKFLKEAGRLTQKEEIPEEELNEDVEEIDHAERELRRGQILWFRGLNRIQTQ 1095
IATIPTSRLKFLKEAGRLTQKEEIPEEELNEDVEEIDHAERELRRGQILWFRGLNRIQTQ
Sbjct: 1081 IATIPTSRLKFLKEAGRLTQKEEIPEEELNEDVEEIDHAERELRRGQILWFRGLNRIQTQ 1140
Query: 1096 IRVVKAFRSSLYEGLEKPESRTSIHNFMAHPEFRIEDSQPHIPLIDDTDLEEDAALKQNS 1155
IRVVKAFRSSLYEGLEKPESRTSIHNFMAHPEFRIEDSQPHIPLIDDTDLEEDAALKQNS
Sbjct: 1141 IRVVKAFRSSLYEGLEKPESRTSIHNFMAHPEFRIEDSQPHIPLIDDTDLEEDAALKQNS 1200
Query: 1156 SPPSSLNKNNSAIDSGINLTTDTSKSATSSSPGSPIHSLETSL 1198
SPPSSLNKNNSAIDSGINLTTDTSKSATSSSPGSPIHSLETSL
Sbjct: 1201 SPPSSLNKNNSAIDSGINLTTDTSKSATSSSPGSPIHSLETSL 1243
>gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo
sapiens]
Length = 1220
Score = 2003 bits (5188), Expect = 0.0
Identities = 1012/1221 (82%), Positives = 1096/1221 (89%), Gaps = 24/1221 (1%)
Query: 1 MGDMTNS--DFYSK-NQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAIC 57
MGDM NS +F+ K Q+ + G FGCT+ ELR+LMELRG EA+ KI+E YGD +C
Sbjct: 1 MGDMANSSIEFHPKPQQQRDVPQAGGFGCTLAELRTLMELRGAEALQKIEEAYGDVSGLC 60
Query: 58 RRLKTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAII 117
RRLKTSP EGL DLEKR+QI+GQNFIPPK+PKTFLQLVWEALQDVTLIILE+AAI+
Sbjct: 61 RRLKTSPTEGLADNTNDLEKRRQIYGQNFIPPKQPKTFLQLVWEALQDVTLIILEVAAIV 120
Query: 118 SLGLSFYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEK 177
SLGLSFY PPGE +E C GGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEK
Sbjct: 121 SLGLSFYAPPGEESEACGNVSGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEK 180
Query: 178 QFRGLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKID 237
QFRGLQSRIEQEQKFTV+R GQ++Q+PVA +VVGDIAQVKYGDLLPADG+ IQ NDLKID
Sbjct: 181 QFRGLQSRIEQEQKFTVIRNGQLLQVPVAALVVGDIAQVKYGDLLPADGVLIQANDLKID 240
Query: 238 ESSLTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEE 297
ESSLTGESD VRKS DKDPMLLSGTHVMEGSGRM+VTAVGVNSQTGIIFTLLGAGGEEEE
Sbjct: 241 ESSLTGESDHVRKSADKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEE 300
Query: 298 KKDKKAKQQDGA--------------AAMEMQPLKSAEGGDADDR--KKASMHKKEKSVL 341
KKDKK KQQDGA AMEMQPLKSAEGG+ ++R KKA+ KKEKSVL
Sbjct: 301 KKDKKGKQQDGAMESSQTKAKKQDGAVAMEMQPLKSAEGGEMEEREKKKANAPKKEKSVL 360
Query: 342 QGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKFFII 401
QGKLTKLAVQIGKAGLVMSAITVIILVLYF ++TFVV + WL ECTPVYVQYFVKFFII
Sbjct: 361 QGKLTKLAVQIGKAGLVMSAITVIILVLYFVIETFVVEGRTWLAECTPVYVQYFVKFFII 420
Query: 402 GVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTT 461
GVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTT
Sbjct: 421 GVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTT 480
Query: 462 NRMTVVQAYVGDVHYKEIPDPSSINTKTMELLINAIAINSAYTTKILPPEKEGALPRQVG 521
NRMTVVQ+Y+GD HYKEIP PS++ K ++LL++AI+INSAYTTKILPPEKEGALPRQVG
Sbjct: 481 NRMTVVQSYLGDTHYKEIPAPSALTPKILDLLVHAISINSAYTTKILPPEKEGALPRQVG 540
Query: 522 NKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKVYTFNSVRKSMSTVIKLPDESFRMYSKG 581
NKTEC LLGFVLDLK+D++PVR Q+PE+KLYKVYTFNSVRKSMSTVI++PD FR++SKG
Sbjct: 541 NKTECALLGFVLDLKRDFQPVREQIPEDKLYKVYTFNSVRKSMSTVIRMPDGGFRLFSKG 600
Query: 582 ASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMACDGLRTICVAYRDFPSSPEPD 641
ASEI+LKKC ILN GE R FRPRDRD+MV+K+IEPMACDGLRTIC+AYRDF + EPD
Sbjct: 601 ASEILLKKCTNILNSNGELRGFRPRDRDDMVRKIIEPMACDGLRTICIAYRDFSAGQEPD 660
Query: 642 WDNENDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKCG 701
WDNEN+++ +LTCI VVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIA KCG
Sbjct: 661 WDNENEVVGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCG 720
Query: 702 IIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDS 761
II PGEDFLCLEGKEFNRRIRNEKGEIEQER+DK+WPKLRVLARSSPTDKHTLVKGIIDS
Sbjct: 721 IIQPGEDFLCLEGKEFNRRIRNEKGEIEQERLDKVWPKLRVLARSSPTDKHTLVKGIIDS 780
Query: 762 THTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVM 821
T EQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNF+SIVKAVM
Sbjct: 781 TTGEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVM 840
Query: 822 WGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALA 881
WGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALA
Sbjct: 841 WGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALA 900
Query: 882 TEPPTETLLLRKPYGRNKPLISRTMMKNILGHAVYQLALIFTLLFVGEKMFQIDSGRNAP 941
TEPPTE+LLLRKPYGR+KPLISRTMMKNILGHAVYQLA+IFTLLFVGE F IDSGRNAP
Sbjct: 901 TEPPTESLLLRKPYGRDKPLISRTMMKNILGHAVYQLAIIFTLLFVGELFFDIDSGRNAP 960
Query: 942 LHSPPSEHYTIIFNTFVMMQLFNEINARKIHGERNVFDGIFRNPIFCTIVLGTFAIQIVI 1001
LHSPPSEHYTIIFNTFVMMQLFNEINARKIHGERNVFDGIF NPIFCTIVLGTF IQIVI
Sbjct: 961 LHSPPSEHYTIIFNTFVMMQLFNEINARKIHGERNVFDGIFSNPIFCTIVLGTFGIQIVI 1020
Query: 1002 VQFGGKPFSCSPLQLDQWMWCIFIGLGELVWGQVIATIPTSRLKFLKEAGRLTQKEEIPE 1061
VQFGGKPFSCSPL +QW+WC+F+G+GELVWGQVIATIPTS+LK LKEAG K+E+ +
Sbjct: 1021 VQFGGKPFSCSPLSTEQWLWCLFVGVGELVWGQVIATIPTSQLKCLKEAGHGPGKDEMTD 1080
Query: 1062 EELNEDVEEIDHAERELRRGQILWFRGLNRIQTQIRVVKAFRSSLYEGLEKPESRTSIHN 1121
EEL E EEIDHAERELRRGQILWFRGLNRIQTQIRVVKAFRSSLYEGLEKPES+TSIHN
Sbjct: 1081 EELAEGEEEIDHAERELRRGQILWFRGLNRIQTQIRVVKAFRSSLYEGLEKPESKTSIHN 1140
Query: 1122 FMAHPEFRIEDSQPHIPLIDDTDLEEDAALKQNSSPPSSLNKNNSAIDSGINLTTDTSKS 1181
FMA PEF I D +IPLIDDTD++E+ + + PP S N+NN+AIDSGI LTT +KS
Sbjct: 1141 FMATPEFLINDYTHNIPLIDDTDVDENEE-RLRAPPPPSPNQNNNAIDSGIYLTTHVTKS 1199
Query: 1182 AT----SSSPGSPIHSLETSL 1198
AT SSSPGSP+HS+ETSL
Sbjct: 1200 ATSSVFSSSPGSPLHSVETSL 1220
>gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo
sapiens]
Length = 1220
Score = 1977 bits (5122), Expect = 0.0
Identities = 991/1221 (81%), Positives = 1092/1221 (89%), Gaps = 24/1221 (1%)
Query: 1 MGDMTNSDF-YS--KNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAIC 57
MGDM N+ YS KN E++H G+FG T+ ELR+LMELR T+A+ KI+E+YGD IC
Sbjct: 1 MGDMANNSVAYSGVKNSLKEANHDGDFGITLAELRALMELRSTDALRKIQESYGDVYGIC 60
Query: 58 RRLKTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAII 117
+LKTSP EGL G DLE+R+ +FG+NFIPPKKPKTFLQLVWEALQDVTLIILEIAAI+
Sbjct: 61 TKLKTSPNEGLSGNPADLERREAVFGKNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIV 120
Query: 118 SLGLSFYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEK 177
SLGLSFY PP N C G E+EGE E GWIEGAAILLSV+CVVLVTAFNDWSKEK
Sbjct: 121 SLGLSFYQPPEGDNALCGEVSVG-EEEGEGETGWIEGAAILLSVVCVVLVTAFNDWSKEK 179
Query: 178 QFRGLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKID 237
QFRGLQSRIEQEQKFTV+R GQV+QIPVA+I VGDIAQVKYGDLLPADG+ IQGNDLKID
Sbjct: 180 QFRGLQSRIEQEQKFTVIRGGQVIQIPVADITVGDIAQVKYGDLLPADGILIQGNDLKID 239
Query: 238 ESSLTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEE 297
ESSLTGESD V+KS+DKDP+LLSGTHVMEGSGRM+VTAVGVNSQTGIIFTLLGAGGEEEE
Sbjct: 240 ESSLTGESDHVKKSLDKDPLLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEE 299
Query: 298 KKD-----KKAKQQDGA------------AAMEMQPLKSAEGGDAD--DRKKASMHKKEK 338
KKD KK K+QDGA AAMEMQPLKS EGGD D D+KKA++ KKEK
Sbjct: 300 KKDEKKKEKKNKKQDGAIENRNKAKAQDGAAMEMQPLKSEEGGDGDEKDKKKANLPKKEK 359
Query: 339 SVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKF 398
SVLQGKLTKLAVQIGKAGL+MSAITVIILVLYF +DTF V K+PWL ECTP+Y+QYFVKF
Sbjct: 360 SVLQGKLTKLAVQIGKAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVKF 419
Query: 399 FIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGT 458
FIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGT
Sbjct: 420 FIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGT 479
Query: 459 LTTNRMTVVQAYVGDVHYKEIPDPSSINTKTMELLINAIAINSAYTTKILPPEKEGALPR 518
LT NRMTVVQAY+ + HYK++P+P +I + L+ I++N AYT+KILPPEKEG LPR
Sbjct: 480 LTMNRMTVVQAYINEKHYKKVPEPEAIPPNILSYLVTGISVNCAYTSKILPPEKEGGLPR 539
Query: 519 QVGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKVYTFNSVRKSMSTVIKLPDESFRMY 578
VGNKTEC LLG +LDLK+DY+ VR+++PEE LYKVYTFNSVRKSMSTV+K D S+R++
Sbjct: 540 HVGNKTECALLGLLLDLKRDYQDVRNEIPEEALYKVYTFNSVRKSMSTVLKNSDGSYRIF 599
Query: 579 SKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMACDGLRTICVAYRDFPSS- 637
SKGASEI+LKKC KIL+ GE +VFRPRDRD++VK VIEPMA +GLRTIC+A+RDFP+
Sbjct: 600 SKGASEIILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASEGLRTICLAFRDFPAGE 659
Query: 638 PEPDWDNENDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIA 697
PEP+WDNENDI+ LTCI VVGIEDPVRPEVP+AI+KCQRAGITVRMVTGDNINTARAIA
Sbjct: 660 PEPEWDNENDIVTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIA 719
Query: 698 IKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKG 757
KCGI+HPGEDFLCLEGK+FNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKG
Sbjct: 720 TKCGILHPGEDFLCLEGKDFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKG 779
Query: 758 IIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIV 817
IIDST ++QRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNF+SIV
Sbjct: 780 IIDSTVSDQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIV 839
Query: 818 KAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFAS 877
KAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDT AS
Sbjct: 840 KAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLAS 899
Query: 878 LALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAVYQLALIFTLLFVGEKMFQIDSG 937
LALATEPPTE+LLLRKPYGRNKPLISRTMMKNILGHA YQL ++FTLLF GEK F IDSG
Sbjct: 900 LALATEPPTESLLLRKPYGRNKPLISRTMMKNILGHAFYQLVVVFTLLFAGEKFFDIDSG 959
Query: 938 RNAPLHSPPSEHYTIIFNTFVMMQLFNEINARKIHGERNVFDGIFRNPIFCTIVLGTFAI 997
RNAPLH+PPSEHYTI+FNTFV+MQLFNEINARKIHGERNVF+GIF N IFCTIVLGTF +
Sbjct: 960 RNAPLHAPPSEHYTIVFNTFVLMQLFNEINARKIHGERNVFEGIFNNAIFCTIVLGTFVV 1019
Query: 998 QIVIVQFGGKPFSCSPLQLDQWMWCIFIGLGELVWGQVIATIPTSRLKFLKEAGRLTQKE 1057
QI+IVQFGGKPFSCS L ++QW+W IF+G+G L+WGQ+I+TIPTSRLKFLKEAG TQKE
Sbjct: 1020 QIIIVQFGGKPFSCSELSIEQWLWSIFLGMGTLLWGQLISTIPTSRLKFLKEAGHGTQKE 1079
Query: 1058 EIPEEELNEDVEEIDHAERELRRGQILWFRGLNRIQTQIRVVKAFRSSLYEGLEKPESRT 1117
EIPEEEL EDVEEIDHAERELRRGQILWFRGLNRIQTQIRVV AFRSSLYEGLEKPESR+
Sbjct: 1080 EIPEEELAEDVEEIDHAERELRRGQILWFRGLNRIQTQIRVVNAFRSSLYEGLEKPESRS 1139
Query: 1118 SIHNFMAHPEFRIEDSQPHIPLIDDTDLEEDAALKQNSSPPSSLNKNNSAIDSGINLTTD 1177
SIHNFM HPEFRIEDS+PHIPLIDDTD E+DA K+NSSPP S NKNN+A+DSGI+LT +
Sbjct: 1140 SIHNFMTHPEFRIEDSEPHIPLIDDTDAEDDAPTKRNSSPPPSPNKNNNAVDSGIHLTIE 1199
Query: 1178 TSKSATSSSPGSPIHSLETSL 1198
+KSATSSSPGSP+HSLETSL
Sbjct: 1200 MNKSATSSSPGSPLHSLETSL 1220
>gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo
sapiens]
Length = 1173
Score = 1878 bits (4864), Expect = 0.0
Identities = 942/1124 (83%), Positives = 1016/1124 (90%), Gaps = 19/1124 (1%)
Query: 1 MGDMTNS--DFYSK-NQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAIC 57
MGDM NS +F+ K Q+ + G FGCT+ ELR+LMELRG EA+ KI+E YGD +C
Sbjct: 1 MGDMANSSIEFHPKPQQQRDVPQAGGFGCTLAELRTLMELRGAEALQKIEEAYGDVSGLC 60
Query: 58 RRLKTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAII 117
RRLKTSP EGL DLEKR+QI+GQNFIPPK+PKTFLQLVWEALQDVTLIILE+AAI+
Sbjct: 61 RRLKTSPTEGLADNTNDLEKRRQIYGQNFIPPKQPKTFLQLVWEALQDVTLIILEVAAIV 120
Query: 118 SLGLSFYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEK 177
SLGLSFY PPGE +E C GGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEK
Sbjct: 121 SLGLSFYAPPGEESEACGNVSGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEK 180
Query: 178 QFRGLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKID 237
QFRGLQSRIEQEQKFTV+R GQ++Q+PVA +VVGDIAQVKYGDLLPADG+ IQ NDLKID
Sbjct: 181 QFRGLQSRIEQEQKFTVIRNGQLLQVPVAALVVGDIAQVKYGDLLPADGVLIQANDLKID 240
Query: 238 ESSLTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEE 297
ESSLTGESD VRKS DKDPMLLSGTHVMEGSGRM+VTAVGVNSQTGIIFTLLGAGGEEEE
Sbjct: 241 ESSLTGESDHVRKSADKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEE 300
Query: 298 KKDKKAKQQDGA--------------AAMEMQPLKSAEGGDADDR--KKASMHKKEKSVL 341
KKDKK KQQDGA AMEMQPLKSAEGG+ ++R KKA+ KKEKSVL
Sbjct: 301 KKDKKGKQQDGAMESSQTKAKKQDGAVAMEMQPLKSAEGGEMEEREKKKANAPKKEKSVL 360
Query: 342 QGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKFFII 401
QGKLTKLAVQIGKAGLVMSAITVIILVLYF ++TFVV + WL ECTPVYVQYFVKFFII
Sbjct: 361 QGKLTKLAVQIGKAGLVMSAITVIILVLYFVIETFVVEGRTWLAECTPVYVQYFVKFFII 420
Query: 402 GVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTT 461
GVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTT
Sbjct: 421 GVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTT 480
Query: 462 NRMTVVQAYVGDVHYKEIPDPSSINTKTMELLINAIAINSAYTTKILPPEKEGALPRQVG 521
NRMTVVQ+Y+GD HYKEIP PS++ K ++LL++AI+INSAYTTKILPPEKEGALPRQVG
Sbjct: 481 NRMTVVQSYLGDTHYKEIPAPSALTPKILDLLVHAISINSAYTTKILPPEKEGALPRQVG 540
Query: 522 NKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKVYTFNSVRKSMSTVIKLPDESFRMYSKG 581
NKTEC LLGFVLDLK+D++PVR Q+PE+KLYKVYTFNSVRKSMSTVI++PD FR++SKG
Sbjct: 541 NKTECALLGFVLDLKRDFQPVREQIPEDKLYKVYTFNSVRKSMSTVIRMPDGGFRLFSKG 600
Query: 582 ASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMACDGLRTICVAYRDFPSSPEPD 641
ASEI+LKKC ILN GE R FRPRDRD+MV+K+IEPMACDGLRTIC+AYRDF + EPD
Sbjct: 601 ASEILLKKCTNILNSNGELRGFRPRDRDDMVRKIIEPMACDGLRTICIAYRDFSAGQEPD 660
Query: 642 WDNENDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKCG 701
WDNEN+++ +LTCI VVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIA KCG
Sbjct: 661 WDNENEVVGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCG 720
Query: 702 IIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDS 761
II PGEDFLCLEGKEFNRRIRNEKGEIEQER+DK+WPKLRVLARSSPTDKHTLVKGIIDS
Sbjct: 721 IIQPGEDFLCLEGKEFNRRIRNEKGEIEQERLDKVWPKLRVLARSSPTDKHTLVKGIIDS 780
Query: 762 THTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVM 821
T EQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNF+SIVKAVM
Sbjct: 781 TTGEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVM 840
Query: 822 WGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALA 881
WGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALA
Sbjct: 841 WGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALA 900
Query: 882 TEPPTETLLLRKPYGRNKPLISRTMMKNILGHAVYQLALIFTLLFVGEKMFQIDSGRNAP 941
TEPPTE+LLLRKPYGR+KPLISRTMMKNILGHAVYQLA+IFTLLFVGE F IDSGRNAP
Sbjct: 901 TEPPTESLLLRKPYGRDKPLISRTMMKNILGHAVYQLAIIFTLLFVGELFFDIDSGRNAP 960
Query: 942 LHSPPSEHYTIIFNTFVMMQLFNEINARKIHGERNVFDGIFRNPIFCTIVLGTFAIQIVI 1001
LHSPPSEHYTIIFNTFVMMQLFNEINARKIHGERNVFDGIF NPIFCTIVLGTF IQIVI
Sbjct: 961 LHSPPSEHYTIIFNTFVMMQLFNEINARKIHGERNVFDGIFSNPIFCTIVLGTFGIQIVI 1020
Query: 1002 VQFGGKPFSCSPLQLDQWMWCIFIGLGELVWGQVIATIPTSRLKFLKEAGRLTQKEEIPE 1061
VQFGGKPFSCSPL +QW+WC+F+G+GELVWGQVIATIPTS+LK LKEAG K+E+ +
Sbjct: 1021 VQFGGKPFSCSPLSTEQWLWCLFVGVGELVWGQVIATIPTSQLKCLKEAGHGPGKDEMTD 1080
Query: 1062 EELNEDVEEIDHAERELRRGQILWFRGLNRIQTQIRVVKAFRSS 1105
EEL E EEIDHAERELRRGQILWFRGLNRIQTQ+ VV F+ S
Sbjct: 1081 EELAEGEEEIDHAERELRRGQILWFRGLNRIQTQMEVVSTFKRS 1124
>gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo
sapiens]
Length = 1176
Score = 1818 bits (4709), Expect = 0.0
Identities = 917/1146 (80%), Positives = 1013/1146 (88%), Gaps = 26/1146 (2%)
Query: 1 MGDMTNSDF-YS--KNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAIC 57
MGDM N+ YS KN E++H G+FG T+ ELR+LMELR T+A+ KI+E+YGD IC
Sbjct: 1 MGDMANNSVAYSGVKNSLKEANHDGDFGITLAELRALMELRSTDALRKIQESYGDVYGIC 60
Query: 58 RRLKTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAII 117
+LKTSP EGL G DLE+R+ +FG+NFIPPKKPKTFLQLVWEALQDVTLIILEIAAI+
Sbjct: 61 TKLKTSPNEGLSGNPADLERREAVFGKNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIV 120
Query: 118 SLGLSFYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEK 177
SLGLSFY PP N C G E+EGE E GWIEGAAILLSV+CVVLVTAFNDWSKEK
Sbjct: 121 SLGLSFYQPPEGDNALCGEVSVG-EEEGEGETGWIEGAAILLSVVCVVLVTAFNDWSKEK 179
Query: 178 QFRGLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKID 237
QFRGLQSRIEQEQKFTV+R GQV+QIPVA+I VGDIAQVKYGDLLPADG+ IQGNDLKID
Sbjct: 180 QFRGLQSRIEQEQKFTVIRGGQVIQIPVADITVGDIAQVKYGDLLPADGILIQGNDLKID 239
Query: 238 ESSLTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEE 297
ESSLTGESD V+KS+DKDP+LLSGTHVMEGSGRM+VTAVGVNSQTGIIFTLLGAGGEEEE
Sbjct: 240 ESSLTGESDHVKKSLDKDPLLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEE 299
Query: 298 KKD-----KKAKQQDGA------------AAMEMQPLKSAEGGDAD--DRKKASMHKKEK 338
KKD KK K+QDGA AAMEMQPLKS EGGD D D+KKA++ KKEK
Sbjct: 300 KKDEKKKEKKNKKQDGAIENRNKAKAQDGAAMEMQPLKSEEGGDGDEKDKKKANLPKKEK 359
Query: 339 SVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKF 398
SVLQGKLTKLAVQIGKAGL+MSAITVIILVLYF +DTF V K+PWL ECTP+Y+QYFVKF
Sbjct: 360 SVLQGKLTKLAVQIGKAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVKF 419
Query: 399 FIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGT 458
FIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGT
Sbjct: 420 FIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGT 479
Query: 459 LTTNRMTVVQAYVGDVHYKEIPDPSSINTKTMELLINAIAINSAYTTKILPPEKEGALPR 518
LT NRMTVVQAY+ + HYK++P+P +I + L+ I++N AYT+KILPPEKEG LPR
Sbjct: 480 LTMNRMTVVQAYINEKHYKKVPEPEAIPPNILSYLVTGISVNCAYTSKILPPEKEGGLPR 539
Query: 519 QVGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKVYTFNSVRKSMSTVIKLPDESFRMY 578
VGNKTEC LLG +LDLK+DY+ VR+++PEE LYKVYTFNSVRKSMSTV+K D S+R++
Sbjct: 540 HVGNKTECALLGLLLDLKRDYQDVRNEIPEEALYKVYTFNSVRKSMSTVLKNSDGSYRIF 599
Query: 579 SKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMACDGLRTICVAYRDFPSS- 637
SKGASEI+LKKC KIL+ GE +VFRPRDRD++VK VIEPMA +GLRTIC+A+RDFP+
Sbjct: 600 SKGASEIILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASEGLRTICLAFRDFPAGE 659
Query: 638 PEPDWDNENDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIA 697
PEP+WDNENDI+ LTCI VVGIEDPVRPEVP+AI+KCQRAGITVRMVTGDNINTARAIA
Sbjct: 660 PEPEWDNENDIVTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIA 719
Query: 698 IKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKG 757
KCGI+HPGEDFLCLEGK+FNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKG
Sbjct: 720 TKCGILHPGEDFLCLEGKDFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKG 779
Query: 758 IIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIV 817
IIDST ++QRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNF+SIV
Sbjct: 780 IIDSTVSDQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIV 839
Query: 818 KAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFAS 877
KAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDT AS
Sbjct: 840 KAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLAS 899
Query: 878 LALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAVYQLALIFTLLFVGEKMFQIDSG 937
LALATEPPTE+LLLRKPYGRNKPLISRTMMKNILGHA YQL ++FTLLF GEK F IDSG
Sbjct: 900 LALATEPPTESLLLRKPYGRNKPLISRTMMKNILGHAFYQLVVVFTLLFAGEKFFDIDSG 959
Query: 938 RNAPLHSPPSEHYTIIFNTFVMMQLFNEINARKIHGERNVFDGIFRNPIFCTIVLGTFAI 997
RNAPLH+PPSEHYTI+FNTFV+MQLFNEINARKIHGERNVF+GIF N IFCTIVLGTF +
Sbjct: 960 RNAPLHAPPSEHYTIVFNTFVLMQLFNEINARKIHGERNVFEGIFNNAIFCTIVLGTFVV 1019
Query: 998 QIVIVQFGGKPFSCSPLQLDQWMWCIFIGLGELVWGQVIATIPTSRLKFLKEAGRLTQKE 1057
QI+IVQFGGKPFSCS L ++QW+W IF+G+G L+WGQ+I+TIPTSRLKFLKEAG TQKE
Sbjct: 1020 QIIIVQFGGKPFSCSELSIEQWLWSIFLGMGTLLWGQLISTIPTSRLKFLKEAGHGTQKE 1079
Query: 1058 EIPEEELNEDVEEIDHAERELRRGQILWFRGLNRIQTQIRVVKAFR--SSLYEGLEKPES 1115
EIPEEEL EDVEEIDHAERELRRGQILWFRGLNRIQTQ+ VV AF+ SS+ L + S
Sbjct: 1080 EIPEEELAEDVEEIDHAERELRRGQILWFRGLNRIQTQMDVVNAFQSGSSIQGALRRQPS 1139
Query: 1116 RTSIHN 1121
S H+
Sbjct: 1140 IASQHH 1145
>gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo
sapiens]
Length = 1205
Score = 1769 bits (4581), Expect = 0.0
Identities = 895/1216 (73%), Positives = 1015/1216 (83%), Gaps = 32/1216 (2%)
Query: 4 MTN-SDFYSKNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAICRRLKT 62
MTN SD S G+FGCT+ ELR LMELR +A+ +I YG + +C RLKT
Sbjct: 1 MTNPSDRVLPANSMAESREGDFGCTVMELRKLMELRSRDALTQINVHYGGVQNLCSRLKT 60
Query: 63 SPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLGLS 122
SPVEGL G DLEKR+Q+FG N IPPKKPKTFL+LVWEALQDVTLIILEIAAIISL LS
Sbjct: 61 SPVEGLSGNPADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLS 120
Query: 123 FYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGL 182
FY P GE NE C EDE EA+AGWIEGAAIL SVI VVLVTAFNDWSKEKQFRGL
Sbjct: 121 FYRPAGEENELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGL 180
Query: 183 QSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESSLT 242
Q RIEQEQKF+++R GQ++Q+PVAEIVVGDIAQVKYGDLLPADG+ IQGNDLKIDESSLT
Sbjct: 181 QCRIEQEQKFSIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLT 240
Query: 243 GESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKDKK 302
GESD V+KS+DKDPMLLSGTHVMEGSGRM+VTAVGVNSQTGII TLLG ++E +K KK
Sbjct: 241 GESDHVKKSLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNEDDEGEKKKK 300
Query: 303 ------------AKQQDGAAAMEMQPLKSAEGGDAD--DRKKASMHKKEKSVLQGKLTKL 348
AK QDG A +E+QPL S EG D + D+K + KKEKSVLQGKLT+L
Sbjct: 301 GKKQGVPENRNKAKTQDGVA-LEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRL 359
Query: 349 AVQIGKAGLVMSAITVIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVV 408
AVQIGKAGL+MSA+TV IL+LYF +D FV+N++PWLPECTP+Y+QYFVKFFIIG+TVLVV
Sbjct: 360 AVQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITVLVV 419
Query: 409 AVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQ 468
AVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLT NRMTVVQ
Sbjct: 420 AVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQ 479
Query: 469 AYVGDVHYKEIPDPSSINTKTMELLINAIAINSAYTTKILPPEKEGALPRQVGNKTECGL 528
AY+G +HY++IP P K ++L++N I+INSAYT+KILPPEKEG LPRQVGNKTEC L
Sbjct: 480 AYIGGIHYRQIPSPDVFLPKVLDLIVNGISINSAYTSKILPPEKEGGLPRQVGNKTECAL 539
Query: 529 LGFVLDLKQDYEPVRSQMPEEKLYKVYTFNSVRKSMSTVIKLPDESFRMYSKGASEIVLK 588
LGFV DLKQDY+ VR+++PEEKLYKVYTFNSVRKSMSTVI+ P+ FRMYSKGASEI+L+
Sbjct: 540 LGFVTDLKQDYQAVRNEVPEEKLYKVYTFNSVRKSMSTVIRNPNGGFRMYSKGASEIILR 599
Query: 589 KCCKILNGAGEPRVFRPRDRDEMVKKVIEPMACDGLRTICVAYRDFPSSPEPDWDNENDI 648
KC +IL+ GE F+ +DRD+MV+ VIEPMACDGLRTIC+AYRDF + EP WDNEN+I
Sbjct: 600 KCNRILDRKGEAVPFKNKDRDDMVRTVIEPMACDGLRTICIAYRDFDDT-EPSWDNENEI 658
Query: 649 LNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPGED 708
L ELTCI VVGIEDPVRPEVP+AI KC++AGITVRMVTGDNINTARAIA KCGI+ PG+D
Sbjct: 659 LTELTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDD 718
Query: 709 FLCLEGKEFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQ 768
FLCLEGKEFNR IRNEKGE+EQE++DKIWPKLRVLARSSPTDKHTLVKGIIDST E RQ
Sbjct: 719 FLCLEGKEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQ 778
Query: 769 VVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYD 828
VVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNF+SIVKAVMWGRNVYD
Sbjct: 779 VVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYD 838
Query: 829 SISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTET 888
SISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTE+
Sbjct: 839 SISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTES 898
Query: 889 LLLRKPYGRNKPLISRTMMKNILGHAVYQLALIFTLLFVGEKMFQIDSGRNAPLHSPPSE 948
LL R+PYGRNKPLISRTMMKNILGHA YQL +IF L+F GEK F IDSGR APLHSPPS+
Sbjct: 899 LLKRRPYGRNKPLISRTMMKNILGHAFYQLIVIFILVFAGEKFFDIDSGRKAPLHSPPSQ 958
Query: 949 HYTIIFNTFVMMQLFNEINARKIHGERNVFDGIFRNPIFCTIVLGTFAIQIVIVQFGGKP 1008
HYTI+FNTFV+MQLFNEIN+RKIHGE+NVF GI+RN IFC++VLGTF QI IV+FGGKP
Sbjct: 959 HYTIVFNTFVLMQLFNEINSRKIHGEKNVFSGIYRNIIFCSVVLGTFICQIFIVEFGGKP 1018
Query: 1009 FSCSPLQLDQWMWCIFIGLGELVWGQVIATIPTSRLKFLKEAGRLTQKEEIPEEELNEDV 1068
FSC+ L L QW+WC+FIG+GEL+WGQ I+ IPT LKFLKEAG T KEEI ++ E +
Sbjct: 1019 FSCTSLSLSQWLWCLFIGIGELLWGQFISAIPTRSLKFLKEAGHGTTKEEITKDA--EGL 1076
Query: 1069 EEIDHAERELRRGQILWFRGLNRIQTQIRVVKAFRSSLYEGLEKPESRTSIHNFMAHPEF 1128
+EIDHAE ELRRGQILWFRGLNRIQTQI+VVKAF SSL+E ++KP ++ SIH+FM HPEF
Sbjct: 1077 DEIDHAEMELRRGQILWFRGLNRIQTQIKVVKAFHSSLHESIQKPYNQKSIHSFMTHPEF 1136
Query: 1129 RIEDSQPHIPLIDDTDLEEDAALKQNSSPPSSLNKNNSAIDSGINLTTDTSKSATSSS-- 1186
IE+ P PL+D+ + ++N S +D + +T+ +A +
Sbjct: 1137 AIEEELPRTPLLDEEE-------EENPDKASKFGTRVLLLDGEVTPYANTNNNAVDCNQV 1189
Query: 1187 ----PGSPIHSLETSL 1198
S + SLETS+
Sbjct: 1190 QLPQSDSSLQSLETSV 1205
>gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo
sapiens]
Length = 1170
Score = 1712 bits (4435), Expect = 0.0
Identities = 860/1116 (77%), Positives = 962/1116 (86%), Gaps = 19/1116 (1%)
Query: 4 MTN-SDFYSKNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAICRRLKT 62
MTN SD S G+FGCT+ ELR LMELR +A+ +I YG + +C RLKT
Sbjct: 1 MTNPSDRVLPANSMAESREGDFGCTVMELRKLMELRSRDALTQINVHYGGVQNLCSRLKT 60
Query: 63 SPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLGLS 122
SPVEGL G DLEKR+Q+FG N IPPKKPKTFL+LVWEALQDVTLIILEIAAIISL LS
Sbjct: 61 SPVEGLSGNPADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLS 120
Query: 123 FYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGL 182
FY P GE NE C EDE EA+AGWIEGAAIL SVI VVLVTAFNDWSKEKQFRGL
Sbjct: 121 FYRPAGEENELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGL 180
Query: 183 QSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESSLT 242
Q RIEQEQKF+++R GQ++Q+PVAEIVVGDIAQVKYGDLLPADG+ IQGNDLKIDESSLT
Sbjct: 181 QCRIEQEQKFSIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLT 240
Query: 243 GESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKDKK 302
GESD V+KS+DKDPMLLSGTHVMEGSGRM+VTAVGVNSQTGII TLLG ++E +K KK
Sbjct: 241 GESDHVKKSLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNEDDEGEKKKK 300
Query: 303 ------------AKQQDGAAAMEMQPLKSAEGGDAD--DRKKASMHKKEKSVLQGKLTKL 348
AK QDG A +E+QPL S EG D + D+K + KKEKSVLQGKLT+L
Sbjct: 301 GKKQGVPENRNKAKTQDGVA-LEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRL 359
Query: 349 AVQIGKAGLVMSAITVIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVV 408
AVQIGKAGL+MSA+TV IL+LYF +D FV+N++PWLPECTP+Y+QYFVKFFIIG+TVLVV
Sbjct: 360 AVQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITVLVV 419
Query: 409 AVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQ 468
AVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLT NRMTVVQ
Sbjct: 420 AVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQ 479
Query: 469 AYVGDVHYKEIPDPSSINTKTMELLINAIAINSAYTTKILPPEKEGALPRQVGNKTECGL 528
AY+G +HY++IP P K ++L++N I+INSAYT+KILPPEKEG LPRQVGNKTEC L
Sbjct: 480 AYIGGIHYRQIPSPDVFLPKVLDLIVNGISINSAYTSKILPPEKEGGLPRQVGNKTECAL 539
Query: 529 LGFVLDLKQDYEPVRSQMPEEKLYKVYTFNSVRKSMSTVIKLPDESFRMYSKGASEIVLK 588
LGFV DLKQDY+ VR+++PEEKLYKVYTFNSVRKSMSTVI+ P+ FRMYSKGASEI+L+
Sbjct: 540 LGFVTDLKQDYQAVRNEVPEEKLYKVYTFNSVRKSMSTVIRNPNGGFRMYSKGASEIILR 599
Query: 589 KCCKILNGAGEPRVFRPRDRDEMVKKVIEPMACDGLRTICVAYRDFPSSPEPDWDNENDI 648
KC +IL+ GE F+ +DRD+MV+ VIEPMACDGLRTIC+AYRDF + EP WDNEN+I
Sbjct: 600 KCNRILDRKGEAVPFKNKDRDDMVRTVIEPMACDGLRTICIAYRDFDDT-EPSWDNENEI 658
Query: 649 LNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPGED 708
L ELTCI VVGIEDPVRPEVP+AI KC++AGITVRMVTGDNINTARAIA KCGI+ PG+D
Sbjct: 659 LTELTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDD 718
Query: 709 FLCLEGKEFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQ 768
FLCLEGKEFNR IRNEKGE+EQE++DKIWPKLRVLARSSPTDKHTLVKGIIDST E RQ
Sbjct: 719 FLCLEGKEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQ 778
Query: 769 VVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYD 828
VVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNF+SIVKAVMWGRNVYD
Sbjct: 779 VVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYD 838
Query: 829 SISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTET 888
SISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTE+
Sbjct: 839 SISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTES 898
Query: 889 LLLRKPYGRNKPLISRTMMKNILGHAVYQLALIFTLLFVGEKMFQIDSGRNAPLHSPPSE 948
LL R+PYGRNKPLISRTMMKNILGHA YQL +IF L+F GEK F IDSGR APLHSPPS+
Sbjct: 899 LLKRRPYGRNKPLISRTMMKNILGHAFYQLIVIFILVFAGEKFFDIDSGRKAPLHSPPSQ 958
Query: 949 HYTIIFNTFVMMQLFNEINARKIHGERNVFDGIFRNPIFCTIVLGTFAIQIVIVQFGGKP 1008
HYTI+FNTFV+MQLFNEIN+RKIHGE+NVF GI+RN IFC++VLGTF QI IV+FGGKP
Sbjct: 959 HYTIVFNTFVLMQLFNEINSRKIHGEKNVFSGIYRNIIFCSVVLGTFICQIFIVEFGGKP 1018
Query: 1009 FSCSPLQLDQWMWCIFIGLGELVWGQVIATIPTSRLKFLKEAGRLTQKEEIPEEELNEDV 1068
FSC+ L L QW+WC+FIG+GEL+WGQ I+ IPT LKFLKEAG T KEEI ++ E +
Sbjct: 1019 FSCTSLSLSQWLWCLFIGIGELLWGQFISAIPTRSLKFLKEAGHGTTKEEITKDA--EGL 1076
Query: 1069 EEIDHAERELRRGQILWFRGLNRIQTQIRVVKAFRS 1104
+EIDHAE ELRRGQILWFRGLNRIQTQI V+ F++
Sbjct: 1077 DEIDHAEMELRRGQILWFRGLNRIQTQIDVINTFQT 1112
>gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [Homo
sapiens]
Length = 997
Score = 303 bits (776), Expect = 6e-82
Identities = 268/903 (29%), Positives = 412/903 (45%), Gaps = 150/903 (16%)
Query: 75 LEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLGLSFYHPPGEGNEGC 134
++K K+ +G N +P ++ KT L+LV E +D+ + IL +AA IS L+++
Sbjct: 29 VKKLKERWGSNELPAEEGKTLLELVIEQFEDLLVRILLLAACISFVLAWF---------- 78
Query: 135 ATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTV 194
E+ E ++E ILL ++ +V + + + E L+ + K
Sbjct: 79 -------EEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKEYEPEMGKVYR 131
Query: 195 VRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLF--IQGNDLKIDESSLTGESDQVRKSV 252
V +I +IV GDI ++ GD +PAD I+ L++D+S LTGES V K
Sbjct: 132 QDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSILTGESVSVIKHT 191
Query: 253 DKDP-----------MLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKDK 301
D P ML SGT++ G +V A GVN++ G
Sbjct: 192 DPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIG------------------ 233
Query: 302 KAKQQDGAAAMEMQPLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSA 361
K +D A E +E++ LQ KL + Q+ K V+S
Sbjct: 234 --KIRDEMVATE----------------------QERTPLQQKLDEFGEQLSK---VISL 266
Query: 362 ITVIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTIS 421
I + + ++ V+ W ++ + +F I V + V A+PEGLP +T
Sbjct: 267 ICIAVWIINIGHFNDPVHGGSW--------IRGAIYYFKIAVALAVAAIPEGLPAVITTC 318
Query: 422 LAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYV---------- 471
LA ++M K N +VR L + ET+G + ICSDKTGTLTTN+M+V + ++
Sbjct: 319 LALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFILDRVEGDTCS 378
Query: 472 --------------GDVHYKEIPDPSSINTKTMELLINAIAINSAYTTKILPPEKEGALP 517
G+VH + P +N + L+ I + L + +
Sbjct: 379 LNEFTITGSTYAPIGEVHKDDKP----VNCHQYDGLVELATICALCNDSALDYNEAKGVY 434
Query: 518 RQVGNKTECGLLGFVLDL-----------KQDYEPVRSQMPEEKLYKVYT--FNSVRKSM 564
+VG TE L V + K + + + ++ + K +T F+ RKSM
Sbjct: 435 EKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKKEFTLEFSRDRKSM 494
Query: 565 STVIKLPDESFR-----MYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPM 619
S V P++ R M+ KGA E V+ +C I G +V + + VI
Sbjct: 495 S-VYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIR--VGSTKVPMTSGVKQKIMSVIREW 551
Query: 620 AC--DGLRTICVAYRDFPSSPEPDW--DNENDILNE--LTCICVVGIEDPVRPEVPEAIR 673
D LR + +A D P E D+ N I E LT + VG+ DP R EV +++
Sbjct: 552 GSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLDPPRIEVASSVK 611
Query: 674 KCQRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERI 733
C++AGI V M+TGDN TA AI + GI ED + K F R E E+
Sbjct: 612 LCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDED---VTSKAFTGR---EFDELNPSAQ 665
Query: 734 DKIWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMG 793
R AR P+ K +V+ + ++ A+TGDG ND PALKKA++G AMG
Sbjct: 666 RDACLNARCFARVEPSHKSKIVEFLQSFD-----EITAMTGDGVNDAPALKKAEIGIAMG 720
Query: 794 IAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGAC 853
+GT VAK AS+++L DDNFS+IV AV GR +Y+++ +F+++ ++ NV V+ F A
Sbjct: 721 -SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA 779
Query: 854 ITQDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGH 913
+ L VQ+LWVNL+ D + AL PP ++ + P +PLIS + L
Sbjct: 780 LGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAI 839
Query: 914 AVY 916
Y
Sbjct: 840 GCY 842
>gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1
[Homo sapiens]
Length = 1042
Score = 303 bits (776), Expect = 6e-82
Identities = 268/903 (29%), Positives = 412/903 (45%), Gaps = 150/903 (16%)
Query: 75 LEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLGLSFYHPPGEGNEGC 134
++K K+ +G N +P ++ KT L+LV E +D+ + IL +AA IS L+++
Sbjct: 29 VKKLKERWGSNELPAEEGKTLLELVIEQFEDLLVRILLLAACISFVLAWF---------- 78
Query: 135 ATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTV 194
E+ E ++E ILL ++ +V + + + E L+ + K
Sbjct: 79 -------EEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKEYEPEMGKVYR 131
Query: 195 VRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLF--IQGNDLKIDESSLTGESDQVRKSV 252
V +I +IV GDI ++ GD +PAD I+ L++D+S LTGES V K
Sbjct: 132 QDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSILTGESVSVIKHT 191
Query: 253 DKDP-----------MLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKDK 301
D P ML SGT++ G +V A GVN++ G
Sbjct: 192 DPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIG------------------ 233
Query: 302 KAKQQDGAAAMEMQPLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSA 361
K +D A E +E++ LQ KL + Q+ K V+S
Sbjct: 234 --KIRDEMVATE----------------------QERTPLQQKLDEFGEQLSK---VISL 266
Query: 362 ITVIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTIS 421
I + + ++ V+ W ++ + +F I V + V A+PEGLP +T
Sbjct: 267 ICIAVWIINIGHFNDPVHGGSW--------IRGAIYYFKIAVALAVAAIPEGLPAVITTC 318
Query: 422 LAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYV---------- 471
LA ++M K N +VR L + ET+G + ICSDKTGTLTTN+M+V + ++
Sbjct: 319 LALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFILDRVEGDTCS 378
Query: 472 --------------GDVHYKEIPDPSSINTKTMELLINAIAINSAYTTKILPPEKEGALP 517
G+VH + P +N + L+ I + L + +
Sbjct: 379 LNEFTITGSTYAPIGEVHKDDKP----VNCHQYDGLVELATICALCNDSALDYNEAKGVY 434
Query: 518 RQVGNKTECGLLGFVLDL-----------KQDYEPVRSQMPEEKLYKVYT--FNSVRKSM 564
+VG TE L V + K + + + ++ + K +T F+ RKSM
Sbjct: 435 EKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKKEFTLEFSRDRKSM 494
Query: 565 STVIKLPDESFR-----MYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPM 619
S V P++ R M+ KGA E V+ +C I G +V + + VI
Sbjct: 495 S-VYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIR--VGSTKVPMTSGVKQKIMSVIREW 551
Query: 620 AC--DGLRTICVAYRDFPSSPEPDW--DNENDILNE--LTCICVVGIEDPVRPEVPEAIR 673
D LR + +A D P E D+ N I E LT + VG+ DP R EV +++
Sbjct: 552 GSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLDPPRIEVASSVK 611
Query: 674 KCQRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERI 733
C++AGI V M+TGDN TA AI + GI ED + K F R E E+
Sbjct: 612 LCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDED---VTSKAFTGR---EFDELNPSAQ 665
Query: 734 DKIWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMG 793
R AR P+ K +V+ + ++ A+TGDG ND PALKKA++G AMG
Sbjct: 666 RDACLNARCFARVEPSHKSKIVEFLQSFD-----EITAMTGDGVNDAPALKKAEIGIAMG 720
Query: 794 IAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGAC 853
+GT VAK AS+++L DDNFS+IV AV GR +Y+++ +F+++ ++ NV V+ F A
Sbjct: 721 -SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA 779
Query: 854 ITQDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGH 913
+ L VQ+LWVNL+ D + AL PP ++ + P +PLIS + L
Sbjct: 780 LGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAI 839
Query: 914 AVY 916
Y
Sbjct: 840 GCY 842
>gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b
[Homo sapiens]
Length = 994
Score = 299 bits (766), Expect = 9e-81
Identities = 271/895 (30%), Positives = 405/895 (45%), Gaps = 148/895 (16%)
Query: 70 GTAPDLEKRK-QIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLGLSFYHPPG 128
G PD KR + +G N +P ++ KT +LV E +D+ + IL +AA IS L+++
Sbjct: 23 GLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRILLLAACISFVLAWF---- 78
Query: 129 EGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQ 188
E+ E ++E ILL +I +V + + + E L+ +
Sbjct: 79 -------------EEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPE 125
Query: 189 EQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADG--LFIQGNDLKIDESSLTGESD 246
K V +I +IV GDI +V GD +PAD L I+ L++D+S LTGES
Sbjct: 126 MGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILTGESV 185
Query: 247 QVRKSV-----------DKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEE 295
V K DK ML SGT++ G +V GV ++ G
Sbjct: 186 SVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIG------------ 233
Query: 296 EEKKDKKAKQQDGAAAMEMQPLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKA 355
K +D AA E ++K+ LQ KL + Q+ K
Sbjct: 234 --------KIRDQMAATE----------------------QDKTPLQQKLDEFGEQLSK- 262
Query: 356 GLVMSAITVIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLP 415
V+S I V + ++ V+ W + +F I V + V A+PEGLP
Sbjct: 263 --VISLICVAVWLINIGHFNDPVHGGSWFRGA--------IYYFKIAVALAVAAIPEGLP 312
Query: 416 LAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYV---- 471
+T LA ++M K N +VR L + ET+G + ICSDKTGTLTTN+M+V + ++
Sbjct: 313 AVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKMFIIDKV 372
Query: 472 -GDV---------------HYKEIPDPSSINTKTMELLINAIAINSAYTTKILPPEKEGA 515
GD+ + + + + + L+ I + L +
Sbjct: 373 DGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCNDSSLDFNEAKG 432
Query: 516 LPRQVGNKTECGLLGFVLDLKQDYEPVRSQMPEEK-----------LYKVYT--FNSVRK 562
+ +VG TE L V + VRS E+ + K +T F+ RK
Sbjct: 433 VYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMKKEFTLEFSRDRK 492
Query: 563 SMSTVIKLPDESFR------MYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVI 616
SMS P +S R M+ KGA E V+ +C + G RV E + VI
Sbjct: 493 SMSVYCS-PAKSSRAAVGNKMFVKGAPEGVIDRCNYVR--VGTTRVPLTGPVKEKIMAVI 549
Query: 617 EPMAC--DGLRTICVAYRDFPSSPEP----DWDNENDILNELTCICVVGIEDPVRPEVPE 670
+ D LR + +A RD P E D + +LT + VVG+ DP R EV
Sbjct: 550 KEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTFVGVVGMLDPPRKEVTG 609
Query: 671 AIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFL--CLEGKEFNRRIRNEKGEI 728
+I+ C+ AGI V M+TGDN TA AI + GI E+ G+EF+ E+ E
Sbjct: 610 SIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDDLPLAEQREA 669
Query: 729 EQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADV 788
+ AR P+ K +V+ + ++ A+TGDG ND PALKKA++
Sbjct: 670 CRRAC--------CFARVEPSHKSKIVEYL-----QSYDEITAMTGDGVNDAPALKKAEI 716
Query: 789 GFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVA 848
G AMG +GT VAK AS+++L DDNFS+IV AV GR +Y+++ +F+++ ++ NV V+
Sbjct: 717 GIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCI 775
Query: 849 FTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLIS 903
F A + L VQ+LWVNL+ D + AL PP ++ R P +PLIS
Sbjct: 776 FLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLIS 830
>gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a
[Homo sapiens]
Length = 1001
Score = 299 bits (766), Expect = 9e-81
Identities = 271/895 (30%), Positives = 405/895 (45%), Gaps = 148/895 (16%)
Query: 70 GTAPDLEKRK-QIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLGLSFYHPPG 128
G PD KR + +G N +P ++ KT +LV E +D+ + IL +AA IS L+++
Sbjct: 23 GLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRILLLAACISFVLAWF---- 78
Query: 129 EGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQ 188
E+ E ++E ILL +I +V + + + E L+ +
Sbjct: 79 -------------EEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPE 125
Query: 189 EQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADG--LFIQGNDLKIDESSLTGESD 246
K V +I +IV GDI +V GD +PAD L I+ L++D+S LTGES
Sbjct: 126 MGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILTGESV 185
Query: 247 QVRKSV-----------DKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEE 295
V K DK ML SGT++ G +V GV ++ G
Sbjct: 186 SVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIG------------ 233
Query: 296 EEKKDKKAKQQDGAAAMEMQPLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKA 355
K +D AA E ++K+ LQ KL + Q+ K
Sbjct: 234 --------KIRDQMAATE----------------------QDKTPLQQKLDEFGEQLSK- 262
Query: 356 GLVMSAITVIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLP 415
V+S I V + ++ V+ W + +F I V + V A+PEGLP
Sbjct: 263 --VISLICVAVWLINIGHFNDPVHGGSWFRGA--------IYYFKIAVALAVAAIPEGLP 312
Query: 416 LAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYV---- 471
+T LA ++M K N +VR L + ET+G + ICSDKTGTLTTN+M+V + ++
Sbjct: 313 AVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKMFIIDKV 372
Query: 472 -GDV---------------HYKEIPDPSSINTKTMELLINAIAINSAYTTKILPPEKEGA 515
GD+ + + + + + L+ I + L +
Sbjct: 373 DGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCNDSSLDFNEAKG 432
Query: 516 LPRQVGNKTECGLLGFVLDLKQDYEPVRSQMPEEK-----------LYKVYT--FNSVRK 562
+ +VG TE L V + VRS E+ + K +T F+ RK
Sbjct: 433 VYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMKKEFTLEFSRDRK 492
Query: 563 SMSTVIKLPDESFR------MYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVI 616
SMS P +S R M+ KGA E V+ +C + G RV E + VI
Sbjct: 493 SMSVYCS-PAKSSRAAVGNKMFVKGAPEGVIDRCNYVR--VGTTRVPLTGPVKEKIMAVI 549
Query: 617 EPMAC--DGLRTICVAYRDFPSSPEP----DWDNENDILNELTCICVVGIEDPVRPEVPE 670
+ D LR + +A RD P E D + +LT + VVG+ DP R EV
Sbjct: 550 KEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTFVGVVGMLDPPRKEVTG 609
Query: 671 AIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFL--CLEGKEFNRRIRNEKGEI 728
+I+ C+ AGI V M+TGDN TA AI + GI E+ G+EF+ E+ E
Sbjct: 610 SIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDDLPLAEQREA 669
Query: 729 EQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADV 788
+ AR P+ K +V+ + ++ A+TGDG ND PALKKA++
Sbjct: 670 CRRAC--------CFARVEPSHKSKIVEYL-----QSYDEITAMTGDGVNDAPALKKAEI 716
Query: 789 GFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVA 848
G AMG +GT VAK AS+++L DDNFS+IV AV GR +Y+++ +F+++ ++ NV V+
Sbjct: 717 GIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCI 775
Query: 849 FTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLIS 903
F A + L VQ+LWVNL+ D + AL PP ++ R P +PLIS
Sbjct: 776 FLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLIS 830
>gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Homo
sapiens]
Length = 999
Score = 297 bits (761), Expect = 4e-80
Identities = 258/900 (28%), Positives = 411/900 (45%), Gaps = 151/900 (16%)
Query: 79 KQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLGLSFYHPPGEGNEGCATAQ 138
++ +G N +P ++ K+ +LV E +D+ + IL +AA++S L+++
Sbjct: 33 RERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWF-------------- 78
Query: 139 GGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVVRAG 198
E+ E ++E I+L ++ +V + + + E L+ + K V+R+
Sbjct: 79 ---EEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKEYEPEMGK--VIRSD 133
Query: 199 Q--VVQIPVAEIVVGDIAQVKYGDLLPADGLFIQ--GNDLKIDESSLTGESDQVRKSV-- 252
+ V +I +IV GDI +V GD +PAD I+ L++D+S LTGES V K
Sbjct: 134 RKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEA 193
Query: 253 ---------DKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKA 303
DK ML SGT++ G + A G++++ G I
Sbjct: 194 IPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKI------------------ 235
Query: 304 KQQDGAAAMEMQPLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAIT 363
R + + + E++ LQ KL + Q+ A +S I
Sbjct: 236 ------------------------RSQMAAVEPERTPLQRKLDEFGRQLSHA---ISVIC 268
Query: 364 VIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLA 423
V + V+ + WL V +F I V + V A+PEGLP +T LA
Sbjct: 269 VAVWVINIGHFADPAHGGSWLRGA--------VYYFKIAVALAVAAIPEGLPAVITTCLA 320
Query: 424 YSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYV------------ 471
++M + N +VR L + ET+G + ICSDKTGTLTTN+M+V + +V
Sbjct: 321 LGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFVVAEADAGSCLLH 380
Query: 472 ------------GDVHYKEIPDPSSINTKTMELLINAIAINSAYTTKILPPEKEGALPRQ 519
G+V + P + + L+ I + L + + +
Sbjct: 381 EFTISGTTYTPEGEVRQGDQP----VRCGQFDGLVELATICALCNDSALDYNEAKGVYEK 436
Query: 520 VGNKTECGLLGFV-------LDLKQDYEPVRS----QMPEEKLYKVYT--FNSVRKSMS- 565
VG TE L V DL+ R+ + ++ + K +T F+ RKSMS
Sbjct: 437 VGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRKEFTLEFSRDRKSMSV 496
Query: 566 ----TVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIE-PMA 620
T + +M+ KGA E V+++C + G+ P R++++ K+ +
Sbjct: 497 YCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGS-RTAPLTPTSREQILAKIRDWGSG 555
Query: 621 CDGLRTICVAYRDFPSSPEP----DWDNENDILNELTCICVVGIEDPVRPEVPEAIRKCQ 676
D LR + +A RD P E D +LT + VG+ DP RPEV I +C
Sbjct: 556 SDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGMLDPPRPEVAACITRCY 615
Query: 677 RAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDKI 736
+AGI V M+TGDN TA AI + GI ED + GK + R E ++ E+ +
Sbjct: 616 QAGIRVVMITGDNKGTAVAICRRLGIFGDTED---VAGKAYTGR---EFDDLSPEQQRQA 669
Query: 737 WPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAG 796
R AR P K +V+ + ++ A+TGDG ND PALKKA++G AMG +G
Sbjct: 670 CRTARCFARVEPAHKSRIVENL-----QSFNEITAMTGDGVNDAPALKKAEIGIAMG-SG 723
Query: 797 TDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQ 856
T VAK A++++L+DDNF+SIV AV GR +Y ++ +F+++ ++ NV V+ F A +
Sbjct: 724 TAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGL 783
Query: 857 DSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAVY 916
L VQ+LWVNL+ D + AL PP ++ + P + LIS + L VY
Sbjct: 784 PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISGWLFFRYLAIGVY 843
>gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Homo
sapiens]
Length = 1029
Score = 297 bits (761), Expect = 4e-80
Identities = 258/900 (28%), Positives = 411/900 (45%), Gaps = 151/900 (16%)
Query: 79 KQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLGLSFYHPPGEGNEGCATAQ 138
++ +G N +P ++ K+ +LV E +D+ + IL +AA++S L+++
Sbjct: 33 RERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWF-------------- 78
Query: 139 GGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVVRAG 198
E+ E ++E I+L ++ +V + + + E L+ + K V+R+
Sbjct: 79 ---EEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKEYEPEMGK--VIRSD 133
Query: 199 Q--VVQIPVAEIVVGDIAQVKYGDLLPADGLFIQ--GNDLKIDESSLTGESDQVRKSV-- 252
+ V +I +IV GDI +V GD +PAD I+ L++D+S LTGES V K
Sbjct: 134 RKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEA 193
Query: 253 ---------DKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKA 303
DK ML SGT++ G + A G++++ G I
Sbjct: 194 IPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKI------------------ 235
Query: 304 KQQDGAAAMEMQPLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAIT 363
R + + + E++ LQ KL + Q+ A +S I
Sbjct: 236 ------------------------RSQMAAVEPERTPLQRKLDEFGRQLSHA---ISVIC 268
Query: 364 VIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLA 423
V + V+ + WL V +F I V + V A+PEGLP +T LA
Sbjct: 269 VAVWVINIGHFADPAHGGSWLRGA--------VYYFKIAVALAVAAIPEGLPAVITTCLA 320
Query: 424 YSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYV------------ 471
++M + N +VR L + ET+G + ICSDKTGTLTTN+M+V + +V
Sbjct: 321 LGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFVVAEADAGSCLLH 380
Query: 472 ------------GDVHYKEIPDPSSINTKTMELLINAIAINSAYTTKILPPEKEGALPRQ 519
G+V + P + + L+ I + L + + +
Sbjct: 381 EFTISGTTYTPEGEVRQGDQP----VRCGQFDGLVELATICALCNDSALDYNEAKGVYEK 436
Query: 520 VGNKTECGLLGFV-------LDLKQDYEPVRS----QMPEEKLYKVYT--FNSVRKSMS- 565
VG TE L V DL+ R+ + ++ + K +T F+ RKSMS
Sbjct: 437 VGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRKEFTLEFSRDRKSMSV 496
Query: 566 ----TVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIE-PMA 620
T + +M+ KGA E V+++C + G+ P R++++ K+ +
Sbjct: 497 YCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGS-RTAPLTPTSREQILAKIRDWGSG 555
Query: 621 CDGLRTICVAYRDFPSSPEP----DWDNENDILNELTCICVVGIEDPVRPEVPEAIRKCQ 676
D LR + +A RD P E D +LT + VG+ DP RPEV I +C
Sbjct: 556 SDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGMLDPPRPEVAACITRCY 615
Query: 677 RAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDKI 736
+AGI V M+TGDN TA AI + GI ED + GK + R E ++ E+ +
Sbjct: 616 QAGIRVVMITGDNKGTAVAICRRLGIFGDTED---VAGKAYTGR---EFDDLSPEQQRQA 669
Query: 737 WPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAG 796
R AR P K +V+ + ++ A+TGDG ND PALKKA++G AMG +G
Sbjct: 670 CRTARCFARVEPAHKSRIVENL-----QSFNEITAMTGDGVNDAPALKKAEIGIAMG-SG 723
Query: 797 TDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQ 856
T VAK A++++L+DDNF+SIV AV GR +Y ++ +F+++ ++ NV V+ F A +
Sbjct: 724 TAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGL 783
Query: 857 DSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAVY 916
L VQ+LWVNL+ D + AL PP ++ + P + LIS + L VY
Sbjct: 784 PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISGWLFFRYLAIGVY 843
>gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Homo
sapiens]
Length = 998
Score = 297 bits (761), Expect = 4e-80
Identities = 258/900 (28%), Positives = 411/900 (45%), Gaps = 151/900 (16%)
Query: 79 KQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLGLSFYHPPGEGNEGCATAQ 138
++ +G N +P ++ K+ +LV E +D+ + IL +AA++S L+++
Sbjct: 33 RERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWF-------------- 78
Query: 139 GGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVVRAG 198
E+ E ++E I+L ++ +V + + + E L+ + K V+R+
Sbjct: 79 ---EEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKEYEPEMGK--VIRSD 133
Query: 199 Q--VVQIPVAEIVVGDIAQVKYGDLLPADGLFIQ--GNDLKIDESSLTGESDQVRKSV-- 252
+ V +I +IV GDI +V GD +PAD I+ L++D+S LTGES V K
Sbjct: 134 RKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEA 193
Query: 253 ---------DKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKA 303
DK ML SGT++ G + A G++++ G I
Sbjct: 194 IPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKI------------------ 235
Query: 304 KQQDGAAAMEMQPLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAIT 363
R + + + E++ LQ KL + Q+ A +S I
Sbjct: 236 ------------------------RSQMAAVEPERTPLQRKLDEFGRQLSHA---ISVIC 268
Query: 364 VIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLA 423
V + V+ + WL V +F I V + V A+PEGLP +T LA
Sbjct: 269 VAVWVINIGHFADPAHGGSWLRGA--------VYYFKIAVALAVAAIPEGLPAVITTCLA 320
Query: 424 YSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYV------------ 471
++M + N +VR L + ET+G + ICSDKTGTLTTN+M+V + +V
Sbjct: 321 LGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFVVAEADAGSCLLH 380
Query: 472 ------------GDVHYKEIPDPSSINTKTMELLINAIAINSAYTTKILPPEKEGALPRQ 519
G+V + P + + L+ I + L + + +
Sbjct: 381 EFTISGTTYTPEGEVRQGDQP----VRCGQFDGLVELATICALCNDSALDYNEAKGVYEK 436
Query: 520 VGNKTECGLLGFV-------LDLKQDYEPVRS----QMPEEKLYKVYT--FNSVRKSMS- 565
VG TE L V DL+ R+ + ++ + K +T F+ RKSMS
Sbjct: 437 VGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRKEFTLEFSRDRKSMSV 496
Query: 566 ----TVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIE-PMA 620
T + +M+ KGA E V+++C + G+ P R++++ K+ +
Sbjct: 497 YCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGS-RTAPLTPTSREQILAKIRDWGSG 555
Query: 621 CDGLRTICVAYRDFPSSPEP----DWDNENDILNELTCICVVGIEDPVRPEVPEAIRKCQ 676
D LR + +A RD P E D +LT + VG+ DP RPEV I +C
Sbjct: 556 SDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGMLDPPRPEVAACITRCY 615
Query: 677 RAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDKI 736
+AGI V M+TGDN TA AI + GI ED + GK + R E ++ E+ +
Sbjct: 616 QAGIRVVMITGDNKGTAVAICRRLGIFGDTED---VAGKAYTGR---EFDDLSPEQQRQA 669
Query: 737 WPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAG 796
R AR P K +V+ + ++ A+TGDG ND PALKKA++G AMG +G
Sbjct: 670 CRTARCFARVEPAHKSRIVENL-----QSFNEITAMTGDGVNDAPALKKAEIGIAMG-SG 723
Query: 797 TDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQ 856
T VAK A++++L+DDNF+SIV AV GR +Y ++ +F+++ ++ NV V+ F A +
Sbjct: 724 TAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGL 783
Query: 857 DSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAVY 916
L VQ+LWVNL+ D + AL PP ++ + P + LIS + L VY
Sbjct: 784 PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISGWLFFRYLAIGVY 843
>gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Homo
sapiens]
Length = 1029
Score = 297 bits (761), Expect = 4e-80
Identities = 258/900 (28%), Positives = 411/900 (45%), Gaps = 151/900 (16%)
Query: 79 KQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLGLSFYHPPGEGNEGCATAQ 138
++ +G N +P ++ K+ +LV E +D+ + IL +AA++S L+++
Sbjct: 33 RERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWF-------------- 78
Query: 139 GGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVVRAG 198
E+ E ++E I+L ++ +V + + + E L+ + K V+R+
Sbjct: 79 ---EEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKEYEPEMGK--VIRSD 133
Query: 199 Q--VVQIPVAEIVVGDIAQVKYGDLLPADGLFIQ--GNDLKIDESSLTGESDQVRKSV-- 252
+ V +I +IV GDI +V GD +PAD I+ L++D+S LTGES V K
Sbjct: 134 RKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEA 193
Query: 253 ---------DKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKA 303
DK ML SGT++ G + A G++++ G I
Sbjct: 194 IPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKI------------------ 235
Query: 304 KQQDGAAAMEMQPLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAIT 363
R + + + E++ LQ KL + Q+ A +S I
Sbjct: 236 ------------------------RSQMAAVEPERTPLQRKLDEFGRQLSHA---ISVIC 268
Query: 364 VIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLA 423
V + V+ + WL V +F I V + V A+PEGLP +T LA
Sbjct: 269 VAVWVINIGHFADPAHGGSWLRGA--------VYYFKIAVALAVAAIPEGLPAVITTCLA 320
Query: 424 YSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYV------------ 471
++M + N +VR L + ET+G + ICSDKTGTLTTN+M+V + +V
Sbjct: 321 LGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFVVAEADAGSCLLH 380
Query: 472 ------------GDVHYKEIPDPSSINTKTMELLINAIAINSAYTTKILPPEKEGALPRQ 519
G+V + P + + L+ I + L + + +
Sbjct: 381 EFTISGTTYTPEGEVRQGDQP----VRCGQFDGLVELATICALCNDSALDYNEAKGVYEK 436
Query: 520 VGNKTECGLLGFV-------LDLKQDYEPVRS----QMPEEKLYKVYT--FNSVRKSMS- 565
VG TE L V DL+ R+ + ++ + K +T F+ RKSMS
Sbjct: 437 VGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRKEFTLEFSRDRKSMSV 496
Query: 566 ----TVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIE-PMA 620
T + +M+ KGA E V+++C + G+ P R++++ K+ +
Sbjct: 497 YCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGS-RTAPLTPTSREQILAKIRDWGSG 555
Query: 621 CDGLRTICVAYRDFPSSPEP----DWDNENDILNELTCICVVGIEDPVRPEVPEAIRKCQ 676
D LR + +A RD P E D +LT + VG+ DP RPEV I +C
Sbjct: 556 SDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGMLDPPRPEVAACITRCY 615
Query: 677 RAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDKI 736
+AGI V M+TGDN TA AI + GI ED + GK + R E ++ E+ +
Sbjct: 616 QAGIRVVMITGDNKGTAVAICRRLGIFGDTED---VAGKAYTGR---EFDDLSPEQQRQA 669
Query: 737 WPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAG 796
R AR P K +V+ + ++ A+TGDG ND PALKKA++G AMG +G
Sbjct: 670 CRTARCFARVEPAHKSRIVENL-----QSFNEITAMTGDGVNDAPALKKAEIGIAMG-SG 723
Query: 797 TDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQ 856
T VAK A++++L+DDNF+SIV AV GR +Y ++ +F+++ ++ NV V+ F A +
Sbjct: 724 TAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGL 783
Query: 857 DSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAVY 916
L VQ+LWVNL+ D + AL PP ++ + P + LIS + L VY
Sbjct: 784 PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISGWLFFRYLAIGVY 843
>gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Homo
sapiens]
Length = 1043
Score = 297 bits (761), Expect = 4e-80
Identities = 258/900 (28%), Positives = 411/900 (45%), Gaps = 151/900 (16%)
Query: 79 KQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLGLSFYHPPGEGNEGCATAQ 138
++ +G N +P ++ K+ +LV E +D+ + IL +AA++S L+++
Sbjct: 33 RERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWF-------------- 78
Query: 139 GGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVVRAG 198
E+ E ++E I+L ++ +V + + + E L+ + K V+R+
Sbjct: 79 ---EEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKEYEPEMGK--VIRSD 133
Query: 199 Q--VVQIPVAEIVVGDIAQVKYGDLLPADGLFIQ--GNDLKIDESSLTGESDQVRKSV-- 252
+ V +I +IV GDI +V GD +PAD I+ L++D+S LTGES V K
Sbjct: 134 RKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEA 193
Query: 253 ---------DKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKA 303
DK ML SGT++ G + A G++++ G I
Sbjct: 194 IPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKI------------------ 235
Query: 304 KQQDGAAAMEMQPLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAIT 363
R + + + E++ LQ KL + Q+ A +S I
Sbjct: 236 ------------------------RSQMAAVEPERTPLQRKLDEFGRQLSHA---ISVIC 268
Query: 364 VIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLA 423
V + V+ + WL V +F I V + V A+PEGLP +T LA
Sbjct: 269 VAVWVINIGHFADPAHGGSWLRGA--------VYYFKIAVALAVAAIPEGLPAVITTCLA 320
Query: 424 YSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYV------------ 471
++M + N +VR L + ET+G + ICSDKTGTLTTN+M+V + +V
Sbjct: 321 LGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFVVAEADAGSCLLH 380
Query: 472 ------------GDVHYKEIPDPSSINTKTMELLINAIAINSAYTTKILPPEKEGALPRQ 519
G+V + P + + L+ I + L + + +
Sbjct: 381 EFTISGTTYTPEGEVRQGDQP----VRCGQFDGLVELATICALCNDSALDYNEAKGVYEK 436
Query: 520 VGNKTECGLLGFV-------LDLKQDYEPVRS----QMPEEKLYKVYT--FNSVRKSMS- 565
VG TE L V DL+ R+ + ++ + K +T F+ RKSMS
Sbjct: 437 VGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRKEFTLEFSRDRKSMSV 496
Query: 566 ----TVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIE-PMA 620
T + +M+ KGA E V+++C + G+ P R++++ K+ +
Sbjct: 497 YCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGS-RTAPLTPTSREQILAKIRDWGSG 555
Query: 621 CDGLRTICVAYRDFPSSPEP----DWDNENDILNELTCICVVGIEDPVRPEVPEAIRKCQ 676
D LR + +A RD P E D +LT + VG+ DP RPEV I +C
Sbjct: 556 SDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGMLDPPRPEVAACITRCY 615
Query: 677 RAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDKI 736
+AGI V M+TGDN TA AI + GI ED + GK + R E ++ E+ +
Sbjct: 616 QAGIRVVMITGDNKGTAVAICRRLGIFGDTED---VAGKAYTGR---EFDDLSPEQQRQA 669
Query: 737 WPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAG 796
R AR P K +V+ + ++ A+TGDG ND PALKKA++G AMG +G
Sbjct: 670 CRTARCFARVEPAHKSRIVENL-----QSFNEITAMTGDGVNDAPALKKAEIGIAMG-SG 723
Query: 797 TDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQ 856
T VAK A++++L+DDNF+SIV AV GR +Y ++ +F+++ ++ NV V+ F A +
Sbjct: 724 TAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGL 783
Query: 857 DSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAVY 916
L VQ+LWVNL+ D + AL PP ++ + P + LIS + L VY
Sbjct: 784 PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISGWLFFRYLAIGVY 843
>gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Homo
sapiens]
Length = 1044
Score = 297 bits (761), Expect = 4e-80
Identities = 258/900 (28%), Positives = 411/900 (45%), Gaps = 151/900 (16%)
Query: 79 KQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLGLSFYHPPGEGNEGCATAQ 138
++ +G N +P ++ K+ +LV E +D+ + IL +AA++S L+++
Sbjct: 33 RERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWF-------------- 78
Query: 139 GGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVVRAG 198
E+ E ++E I+L ++ +V + + + E L+ + K V+R+
Sbjct: 79 ---EEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKEYEPEMGK--VIRSD 133
Query: 199 Q--VVQIPVAEIVVGDIAQVKYGDLLPADGLFIQ--GNDLKIDESSLTGESDQVRKSV-- 252
+ V +I +IV GDI +V GD +PAD I+ L++D+S LTGES V K
Sbjct: 134 RKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEA 193
Query: 253 ---------DKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKA 303
DK ML SGT++ G + A G++++ G I
Sbjct: 194 IPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKI------------------ 235
Query: 304 KQQDGAAAMEMQPLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAIT 363
R + + + E++ LQ KL + Q+ A +S I
Sbjct: 236 ------------------------RSQMAAVEPERTPLQRKLDEFGRQLSHA---ISVIC 268
Query: 364 VIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLA 423
V + V+ + WL V +F I V + V A+PEGLP +T LA
Sbjct: 269 VAVWVINIGHFADPAHGGSWLRGA--------VYYFKIAVALAVAAIPEGLPAVITTCLA 320
Query: 424 YSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYV------------ 471
++M + N +VR L + ET+G + ICSDKTGTLTTN+M+V + +V
Sbjct: 321 LGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFVVAEADAGSCLLH 380
Query: 472 ------------GDVHYKEIPDPSSINTKTMELLINAIAINSAYTTKILPPEKEGALPRQ 519
G+V + P + + L+ I + L + + +
Sbjct: 381 EFTISGTTYTPEGEVRQGDQP----VRCGQFDGLVELATICALCNDSALDYNEAKGVYEK 436
Query: 520 VGNKTECGLLGFV-------LDLKQDYEPVRS----QMPEEKLYKVYT--FNSVRKSMS- 565
VG TE L V DL+ R+ + ++ + K +T F+ RKSMS
Sbjct: 437 VGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRKEFTLEFSRDRKSMSV 496
Query: 566 ----TVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIE-PMA 620
T + +M+ KGA E V+++C + G+ P R++++ K+ +
Sbjct: 497 YCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGS-RTAPLTPTSREQILAKIRDWGSG 555
Query: 621 CDGLRTICVAYRDFPSSPEP----DWDNENDILNELTCICVVGIEDPVRPEVPEAIRKCQ 676
D LR + +A RD P E D +LT + VG+ DP RPEV I +C
Sbjct: 556 SDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGMLDPPRPEVAACITRCY 615
Query: 677 RAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDKI 736
+AGI V M+TGDN TA AI + GI ED + GK + R E ++ E+ +
Sbjct: 616 QAGIRVVMITGDNKGTAVAICRRLGIFGDTED---VAGKAYTGR---EFDDLSPEQQRQA 669
Query: 737 WPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAG 796
R AR P K +V+ + ++ A+TGDG ND PALKKA++G AMG +G
Sbjct: 670 CRTARCFARVEPAHKSRIVENL-----QSFNEITAMTGDGVNDAPALKKAEIGIAMG-SG 723
Query: 797 TDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQ 856
T VAK A++++L+DDNF+SIV AV GR +Y ++ +F+++ ++ NV V+ F A +
Sbjct: 724 TAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGL 783
Query: 857 DSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAVY 916
L VQ+LWVNL+ D + AL PP ++ + P + LIS + L VY
Sbjct: 784 PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISGWLFFRYLAIGVY 843
>gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Homo
sapiens]
Length = 1052
Score = 297 bits (761), Expect = 4e-80
Identities = 258/900 (28%), Positives = 411/900 (45%), Gaps = 151/900 (16%)
Query: 79 KQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLGLSFYHPPGEGNEGCATAQ 138
++ +G N +P ++ K+ +LV E +D+ + IL +AA++S L+++
Sbjct: 33 RERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWF-------------- 78
Query: 139 GGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVVRAG 198
E+ E ++E I+L ++ +V + + + E L+ + K V+R+
Sbjct: 79 ---EEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKEYEPEMGK--VIRSD 133
Query: 199 Q--VVQIPVAEIVVGDIAQVKYGDLLPADGLFIQ--GNDLKIDESSLTGESDQVRKSV-- 252
+ V +I +IV GDI +V GD +PAD I+ L++D+S LTGES V K
Sbjct: 134 RKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEA 193
Query: 253 ---------DKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKA 303
DK ML SGT++ G + A G++++ G I
Sbjct: 194 IPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKI------------------ 235
Query: 304 KQQDGAAAMEMQPLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAIT 363
R + + + E++ LQ KL + Q+ A +S I
Sbjct: 236 ------------------------RSQMAAVEPERTPLQRKLDEFGRQLSHA---ISVIC 268
Query: 364 VIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLA 423
V + V+ + WL V +F I V + V A+PEGLP +T LA
Sbjct: 269 VAVWVINIGHFADPAHGGSWLRGA--------VYYFKIAVALAVAAIPEGLPAVITTCLA 320
Query: 424 YSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYV------------ 471
++M + N +VR L + ET+G + ICSDKTGTLTTN+M+V + +V
Sbjct: 321 LGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFVVAEADAGSCLLH 380
Query: 472 ------------GDVHYKEIPDPSSINTKTMELLINAIAINSAYTTKILPPEKEGALPRQ 519
G+V + P + + L+ I + L + + +
Sbjct: 381 EFTISGTTYTPEGEVRQGDQP----VRCGQFDGLVELATICALCNDSALDYNEAKGVYEK 436
Query: 520 VGNKTECGLLGFV-------LDLKQDYEPVRS----QMPEEKLYKVYT--FNSVRKSMS- 565
VG TE L V DL+ R+ + ++ + K +T F+ RKSMS
Sbjct: 437 VGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRKEFTLEFSRDRKSMSV 496
Query: 566 ----TVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIE-PMA 620
T + +M+ KGA E V+++C + G+ P R++++ K+ +
Sbjct: 497 YCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGS-RTAPLTPTSREQILAKIRDWGSG 555
Query: 621 CDGLRTICVAYRDFPSSPEP----DWDNENDILNELTCICVVGIEDPVRPEVPEAIRKCQ 676
D LR + +A RD P E D +LT + VG+ DP RPEV I +C
Sbjct: 556 SDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGMLDPPRPEVAACITRCY 615
Query: 677 RAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDKI 736
+AGI V M+TGDN TA AI + GI ED + GK + R E ++ E+ +
Sbjct: 616 QAGIRVVMITGDNKGTAVAICRRLGIFGDTED---VAGKAYTGR---EFDDLSPEQQRQA 669
Query: 737 WPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAG 796
R AR P K +V+ + ++ A+TGDG ND PALKKA++G AMG +G
Sbjct: 670 CRTARCFARVEPAHKSRIVENL-----QSFNEITAMTGDGVNDAPALKKAEIGIAMG-SG 723
Query: 797 TDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQ 856
T VAK A++++L+DDNF+SIV AV GR +Y ++ +F+++ ++ NV V+ F A +
Sbjct: 724 TAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGL 783
Query: 857 DSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAVY 916
L VQ+LWVNL+ D + AL PP ++ + P + LIS + L VY
Sbjct: 784 PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISGWLFFRYLAIGVY 843
>gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sapiens]
Length = 939
Score = 293 bits (751), Expect = 5e-79
Identities = 247/913 (27%), Positives = 421/913 (46%), Gaps = 124/913 (13%)
Query: 153 EGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGD 212
+ +I ++++ VV V ++ EK L + E VR G++ ++V GD
Sbjct: 102 DAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECH--CVREGKLEHTLARDLVPGD 159
Query: 213 IAQVKYGDLLPADGLFIQGNDLKIDESSLTGESDQVRKSVDKDPMLLSGTHVMEGSGRML 272
+ GD +PAD + DL IDESSLTGE+ K P +G + +
Sbjct: 160 TVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIAFM 219
Query: 273 VTAVGVNSQTGIIFTLLGAGGEEEEKKDKKAKQQDGAAAMEMQPLKSAEGGDADDRKKAS 332
T V G++ +G G E + K Q + A +Q
Sbjct: 220 GTLVRCGKAKGVV---IGTGENSEFGEVFKMMQAEEAPKTPLQ----------------- 259
Query: 333 MHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDTFVVNKKPWLPECTPVYV 392
K +L +L+ + I I +I+LV WL
Sbjct: 260 ---KSMDLLGKQLSFYSFGI---------IGIIMLV-------------GWL------LG 288
Query: 393 QYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAIC 452
+ ++ F I V++ V A+PEGLP+ VT++LA V +M+K +V+ L ET+G IC
Sbjct: 289 KDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVIC 348
Query: 453 SDKTGTLTTNRMTVVQAYVGDVHYKEIPDPSSINTKTMELLINAIAINSAYTTKILPPEK 512
SDKTGTLT N MTV + D + E+ + E++++ ++ Y + +
Sbjct: 349 SDKTGTLTKNEMTVTHIFTSDGLHAEVTGVGY--NQFGEVIVDGDVVHGFYNPAVSRIVE 406
Query: 513 EGALPRQ--------VGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKV-YTFNSVRKS 563
G + +G TE L+ + + D + ++ + K Y F+S +K
Sbjct: 407 AGCVCNDAVIRNNTLMGKPTEGALIALAMKMGLD------GLQQDYIRKAEYPFSSEQKW 460
Query: 564 MSTVIKLPDESFR---MYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMA 620
M+ + R + KGA E V+K C G+ + RD ++ M
Sbjct: 461 MAVKCVHRTQQDRPEICFMKGAYEQVIKYCTTY-QSKGQTLTLTQQQRDVYQQEKAR-MG 518
Query: 621 CDGLRTICVAYRDFPSSPEPDWDNENDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGI 680
GLR + +A S PE L +LT + +VGI DP R V EA+ +G+
Sbjct: 519 SAGLRVLALA-----SGPE---------LGQLTFLGLVGIIDPPRTGVKEAVTTLIASGV 564
Query: 681 TVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDKIWPKL 740
+++M+TGD+ TA AIA + G+ + G+E + ++ +++ +I PK+
Sbjct: 565 SIKMITGDSQETAVAIASRLGLYSKTSQ--SVSGEEIDA--------MDVQQLSQIVPKV 614
Query: 741 RVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVA 800
V R+SP K ++K + + VVA+TGDG ND ALK AD+G AMG GTDV
Sbjct: 615 AVFYRASPRHKMKIIKSL-----QKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVC 669
Query: 801 KEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPL 860
KEA+D+IL DD+F +I+ A+ G+ +Y++I F++FQL+ ++ A+ + + +PL
Sbjct: 670 KEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPL 729
Query: 861 KAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAVYQLAL 920
A+Q+LW+N+IMD + +L EP + ++ + P ++++ ++ IL V + +
Sbjct: 730 NAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKIL---VSSIII 786
Query: 921 IFTLLFV--GEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARKIHGERNVF 978
+ LFV E + + R+ T+ F FV +FN +++R ++VF
Sbjct: 787 VCGTLFVFWRELRDNVITPRDT----------TMTFTCFVFFDMFNALSSRS--QTKSVF 834
Query: 979 D-GIFRNPIFCTIVLGTFAIQIVIVQFG--GKPFSCSPLQLDQWMWCIFIGLGELVWGQV 1035
+ G+ N +FC VLG+ Q++++ F K F L + ++ + + + ++
Sbjct: 835 EIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSILDLLFLLGLTSSVCIVAEI 894
Query: 1036 IATIPTSRLKFLK 1048
I + SR K K
Sbjct: 895 IKKVERSREKIQK 907
>gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo sapiens]
Length = 949
Score = 293 bits (751), Expect = 5e-79
Identities = 247/913 (27%), Positives = 421/913 (46%), Gaps = 124/913 (13%)
Query: 153 EGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGD 212
+ +I ++++ VV V ++ EK L + E VR G++ ++V GD
Sbjct: 102 DAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECH--CVREGKLEHTLARDLVPGD 159
Query: 213 IAQVKYGDLLPADGLFIQGNDLKIDESSLTGESDQVRKSVDKDPMLLSGTHVMEGSGRML 272
+ GD +PAD + DL IDESSLTGE+ K P +G + +
Sbjct: 160 TVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIAFM 219
Query: 273 VTAVGVNSQTGIIFTLLGAGGEEEEKKDKKAKQQDGAAAMEMQPLKSAEGGDADDRKKAS 332
T V G++ +G G E + K Q + A +Q
Sbjct: 220 GTLVRCGKAKGVV---IGTGENSEFGEVFKMMQAEEAPKTPLQ----------------- 259
Query: 333 MHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDTFVVNKKPWLPECTPVYV 392
K +L +L+ + I I +I+LV WL
Sbjct: 260 ---KSMDLLGKQLSFYSFGI---------IGIIMLV-------------GWL------LG 288
Query: 393 QYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAIC 452
+ ++ F I V++ V A+PEGLP+ VT++LA V +M+K +V+ L ET+G IC
Sbjct: 289 KDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVIC 348
Query: 453 SDKTGTLTTNRMTVVQAYVGDVHYKEIPDPSSINTKTMELLINAIAINSAYTTKILPPEK 512
SDKTGTLT N MTV + D + E+ + E++++ ++ Y + +
Sbjct: 349 SDKTGTLTKNEMTVTHIFTSDGLHAEVTGVGY--NQFGEVIVDGDVVHGFYNPAVSRIVE 406
Query: 513 EGALPRQ--------VGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKV-YTFNSVRKS 563
G + +G TE L+ + + D + ++ + K Y F+S +K
Sbjct: 407 AGCVCNDAVIRNNTLMGKPTEGALIALAMKMGLD------GLQQDYIRKAEYPFSSEQKW 460
Query: 564 MSTVIKLPDESFR---MYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMA 620
M+ + R + KGA E V+K C G+ + RD ++ M
Sbjct: 461 MAVKCVHRTQQDRPEICFMKGAYEQVIKYCTTY-QSKGQTLTLTQQQRDVYQQEKAR-MG 518
Query: 621 CDGLRTICVAYRDFPSSPEPDWDNENDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGI 680
GLR + +A S PE L +LT + +VGI DP R V EA+ +G+
Sbjct: 519 SAGLRVLALA-----SGPE---------LGQLTFLGLVGIIDPPRTGVKEAVTTLIASGV 564
Query: 681 TVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDKIWPKL 740
+++M+TGD+ TA AIA + G+ + G+E + ++ +++ +I PK+
Sbjct: 565 SIKMITGDSQETAVAIASRLGLYSKTSQ--SVSGEEIDA--------MDVQQLSQIVPKV 614
Query: 741 RVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVA 800
V R+SP K ++K + + VVA+TGDG ND ALK AD+G AMG GTDV
Sbjct: 615 AVFYRASPRHKMKIIKSL-----QKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVC 669
Query: 801 KEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPL 860
KEA+D+IL DD+F +I+ A+ G+ +Y++I F++FQL+ ++ A+ + + +PL
Sbjct: 670 KEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPL 729
Query: 861 KAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAVYQLAL 920
A+Q+LW+N+IMD + +L EP + ++ + P ++++ ++ IL V + +
Sbjct: 730 NAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKIL---VSSIII 786
Query: 921 IFTLLFV--GEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARKIHGERNVF 978
+ LFV E + + R+ T+ F FV +FN +++R ++VF
Sbjct: 787 VCGTLFVFWRELRDNVITPRDT----------TMTFTCFVFFDMFNALSSRS--QTKSVF 834
Query: 979 D-GIFRNPIFCTIVLGTFAIQIVIVQFG--GKPFSCSPLQLDQWMWCIFIGLGELVWGQV 1035
+ G+ N +FC VLG+ Q++++ F K F L + ++ + + + ++
Sbjct: 835 EIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSILDLLFLLGLTSSVCIVAEI 894
Query: 1036 IATIPTSRLKFLK 1048
I + SR K K
Sbjct: 895 IKKVERSREKIQK 907
>gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo sapiens]
Length = 919
Score = 293 bits (751), Expect = 5e-79
Identities = 247/913 (27%), Positives = 421/913 (46%), Gaps = 124/913 (13%)
Query: 153 EGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGD 212
+ +I ++++ VV V ++ EK L + E VR G++ ++V GD
Sbjct: 102 DAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECH--CVREGKLEHTLARDLVPGD 159
Query: 213 IAQVKYGDLLPADGLFIQGNDLKIDESSLTGESDQVRKSVDKDPMLLSGTHVMEGSGRML 272
+ GD +PAD + DL IDESSLTGE+ K P +G + +
Sbjct: 160 TVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIAFM 219
Query: 273 VTAVGVNSQTGIIFTLLGAGGEEEEKKDKKAKQQDGAAAMEMQPLKSAEGGDADDRKKAS 332
T V G++ +G G E + K Q + A +Q
Sbjct: 220 GTLVRCGKAKGVV---IGTGENSEFGEVFKMMQAEEAPKTPLQ----------------- 259
Query: 333 MHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDTFVVNKKPWLPECTPVYV 392
K +L +L+ + I I +I+LV WL
Sbjct: 260 ---KSMDLLGKQLSFYSFGI---------IGIIMLV-------------GWL------LG 288
Query: 393 QYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAIC 452
+ ++ F I V++ V A+PEGLP+ VT++LA V +M+K +V+ L ET+G IC
Sbjct: 289 KDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVIC 348
Query: 453 SDKTGTLTTNRMTVVQAYVGDVHYKEIPDPSSINTKTMELLINAIAINSAYTTKILPPEK 512
SDKTGTLT N MTV + D + E+ + E++++ ++ Y + +
Sbjct: 349 SDKTGTLTKNEMTVTHIFTSDGLHAEVTGVGY--NQFGEVIVDGDVVHGFYNPAVSRIVE 406
Query: 513 EGALPRQ--------VGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKV-YTFNSVRKS 563
G + +G TE L+ + + D + ++ + K Y F+S +K
Sbjct: 407 AGCVCNDAVIRNNTLMGKPTEGALIALAMKMGLD------GLQQDYIRKAEYPFSSEQKW 460
Query: 564 MSTVIKLPDESFR---MYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMA 620
M+ + R + KGA E V+K C G+ + RD ++ M
Sbjct: 461 MAVKCVHRTQQDRPEICFMKGAYEQVIKYCTTY-QSKGQTLTLTQQQRDVYQQEKAR-MG 518
Query: 621 CDGLRTICVAYRDFPSSPEPDWDNENDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGI 680
GLR + +A S PE L +LT + +VGI DP R V EA+ +G+
Sbjct: 519 SAGLRVLALA-----SGPE---------LGQLTFLGLVGIIDPPRTGVKEAVTTLIASGV 564
Query: 681 TVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDKIWPKL 740
+++M+TGD+ TA AIA + G+ + G+E + ++ +++ +I PK+
Sbjct: 565 SIKMITGDSQETAVAIASRLGLYSKTSQ--SVSGEEIDA--------MDVQQLSQIVPKV 614
Query: 741 RVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVA 800
V R+SP K ++K + + VVA+TGDG ND ALK AD+G AMG GTDV
Sbjct: 615 AVFYRASPRHKMKIIKSL-----QKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVC 669
Query: 801 KEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPL 860
KEA+D+IL DD+F +I+ A+ G+ +Y++I F++FQL+ ++ A+ + + +PL
Sbjct: 670 KEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPL 729
Query: 861 KAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAVYQLAL 920
A+Q+LW+N+IMD + +L EP + ++ + P ++++ ++ IL V + +
Sbjct: 730 NAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKIL---VSSIII 786
Query: 921 IFTLLFV--GEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARKIHGERNVF 978
+ LFV E + + R+ T+ F FV +FN +++R ++VF
Sbjct: 787 VCGTLFVFWRELRDNVITPRDT----------TMTFTCFVFFDMFNALSSRS--QTKSVF 834
Query: 979 D-GIFRNPIFCTIVLGTFAIQIVIVQFG--GKPFSCSPLQLDQWMWCIFIGLGELVWGQV 1035
+ G+ N +FC VLG+ Q++++ F K F L + ++ + + + ++
Sbjct: 835 EIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSILDLLFLLGLTSSVCIVAEI 894
Query: 1036 IATIPTSRLKFLK 1048
I + SR K K
Sbjct: 895 IKKVERSREKIQK 907
>gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo sapiens]
Length = 888
Score = 290 bits (743), Expect = 4e-78
Identities = 239/867 (27%), Positives = 404/867 (46%), Gaps = 122/867 (14%)
Query: 153 EGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGD 212
+ +I ++++ VV V ++ EK L + E VR G++ ++V GD
Sbjct: 102 DAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECH--CVREGKLEHTLARDLVPGD 159
Query: 213 IAQVKYGDLLPADGLFIQGNDLKIDESSLTGESDQVRKSVDKDPMLLSGTHVMEGSGRML 272
+ GD +PAD + DL IDESSLTGE+ K P +G + +
Sbjct: 160 TVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIAFM 219
Query: 273 VTAVGVNSQTGIIFTLLGAGGEEEEKKDKKAKQQDGAAAMEMQPLKSAEGGDADDRKKAS 332
T V G++ +G G E + K Q + A +Q
Sbjct: 220 GTLVRCGKAKGVV---IGTGENSEFGEVFKMMQAEEAPKTPLQ----------------- 259
Query: 333 MHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDTFVVNKKPWLPECTPVYV 392
K +L +L+ + I I +I+LV WL
Sbjct: 260 ---KSMDLLGKQLSFYSFGI---------IGIIMLV-------------GWL------LG 288
Query: 393 QYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAIC 452
+ ++ F I V++ V A+PEGLP+ VT++LA V +M+K +V+ L ET+G IC
Sbjct: 289 KDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVIC 348
Query: 453 SDKTGTLTTNRMTVVQAYVGDVHYKEIPDPSSINTKTMELLINAIAINSAYTTKILPPEK 512
SDKTGTLT N MTV + D + E+ + E++++ ++ Y + +
Sbjct: 349 SDKTGTLTKNEMTVTHIFTSDGLHAEVTGVGY--NQFGEVIVDGDVVHGFYNPAVSRIVE 406
Query: 513 EGALPRQ--------VGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKV-YTFNSVRKS 563
G + +G TE L+ + + D + ++ + K Y F+S +K
Sbjct: 407 AGCVCNDAVIRNNTLMGKPTEGALIALAMKMGLD------GLQQDYIRKAEYPFSSEQKW 460
Query: 564 MSTVIKLPDESFR---MYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMA 620
M+ + R + KGA E V+K C G+ + RD ++ M
Sbjct: 461 MAVKCVHRTQQDRPEICFMKGAYEQVIKYCTTY-QSKGQTLTLTQQQRDVYQQEKAR-MG 518
Query: 621 CDGLRTICVAYRDFPSSPEPDWDNENDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGI 680
GLR + +A S PE L +LT + +VGI DP R V EA+ +G+
Sbjct: 519 SAGLRVLALA-----SGPE---------LGQLTFLGLVGIIDPPRTGVKEAVTTLIASGV 564
Query: 681 TVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDKIWPKL 740
+++M+TGD+ TA AIA + G+ + G+E + ++ +++ +I PK+
Sbjct: 565 SIKMITGDSQETAVAIASRLGLYSKTSQ--SVSGEEIDA--------MDVQQLSQIVPKV 614
Query: 741 RVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVA 800
V R+SP K ++K + + VVA+TGDG ND ALK AD+G AMG GTDV
Sbjct: 615 AVFYRASPRHKMKIIKSL-----QKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVC 669
Query: 801 KEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPL 860
KEA+D+IL DD+F +I+ A+ G+ +Y++I F++FQL+ ++ A+ + + +PL
Sbjct: 670 KEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPL 729
Query: 861 KAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAVYQLAL 920
A+Q+LW+N+IMD + +L EP + ++ + P ++++ ++ IL V + +
Sbjct: 730 NAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKIL---VSSIII 786
Query: 921 IFTLLFV--GEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARKIHGERNVF 978
+ LFV E + + R+ T+ F FV +FN +++R ++VF
Sbjct: 787 VCGTLFVFWRELRDNVITPRDT----------TMTFTCFVFFDMFNALSSRS--QTKSVF 834
Query: 979 D-GIFRNPIFCTIVLGTFAIQIVIVQF 1004
+ G+ N +FC VLG+ Q++++ F
Sbjct: 835 EIGLCSNRMFCYAVLGSIMGQLLVIYF 861
>gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo
sapiens]
Length = 946
Score = 283 bits (723), Expect = 9e-76
Identities = 246/862 (28%), Positives = 399/862 (46%), Gaps = 116/862 (13%)
Query: 153 EGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGD 212
+ +I +V+ VV V ++ EK L + E +R G++ + E+V GD
Sbjct: 133 DAVSIATAVLVVVTVAFIQEYRSEKSLEELTKMVPPE--CNCLREGKLQHLLARELVPGD 190
Query: 213 IAQVKYGDLLPADGLFIQGNDLKIDESSLTGESDQVRKSVDKDPMLLSGTHVMEGSGRML 272
+ + GD +PAD + DL +DESS TGE++ K+ D L G + S +
Sbjct: 191 VVSLSIGDRIPADIRLTEVTDLLVDESSFTGEAEPCSKT---DSPLTGGGDLTTLSNIVF 247
Query: 273 V-TAVGVNSQTGIIFTLLGAGGEEEEKKDKKAKQQDGAAAMEMQPLKSAEGGDADDRKKA 331
+ T V G++ +G G +S++ G+ +A
Sbjct: 248 MGTLVQYGRGQGVV---IGTG-------------------------ESSQFGEVFKMMQA 279
Query: 332 SMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDTFVVNKKPWLPECTPVY 391
+ K+ LQ + +L Q+ L I +I+++ ++
Sbjct: 280 E--ETPKTPLQKSMDRLGKQLT---LFSFGIIGLIMLIGWSQG----------------- 317
Query: 392 VQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAI 451
+ + F IGV++ V A+PEGLP+ V ++L V +M K +V+ L ET+G + +
Sbjct: 318 -KQLLSMFTIGVSLAVAAIPEGLPIVVMVTLVLGVLRMAKKRVIVKKLPIVETLGCCSVL 376
Query: 452 CSDKTGTLTTNRMTVVQAYVGDVHYKEIPDPSSINTKTMELLINAIAINSAYTTKILPPE 511
CSDKTGTLT N MTV Q D E+ T+ LL + I +
Sbjct: 377 CSDKTGTLTANEMTVTQLVTSDGLRAEVSGVGYDGQGTVCLLPSKEVIKEFSNVSVGKLV 436
Query: 512 KEGALPRQ--------VGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKVYTFNSVRKS 563
+ G + +G TE L+ L +K D +++ +K F+S +K
Sbjct: 437 EAGCVANNAVIRKNAVMGQPTEGALMA--LAMKMDLSDIKNSYIRKK---EIPFSSEQKW 491
Query: 564 MSTV--IKLPDESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMAC 621
M+ +K D+ + KGA E V++ C NG G P P+ R +++ + M
Sbjct: 492 MAVKCSLKTEDQEDIYFMKGALEEVIRYCTMYNNG-GIPLPLTPQQRSFCLQEE-KRMGS 549
Query: 622 DGLRTICVAYRDFPSSPEPDWDNENDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGIT 681
GLR + +A S PE L LT + +VGI DP R V EA++ +G++
Sbjct: 550 LGLRVLALA-----SGPE---------LGRLTFLGLVGIIDPPRVGVKEAVQVLSESGVS 595
Query: 682 VRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDKIWPKLR 741
V+M+TGD + TA AI G+ + + G+E + EKGE+ +R+ K+
Sbjct: 596 VKMITGDALETALAIGRNIGLCNG--KLQAMSGEEVDSV---EKGELA-DRVGKV----S 645
Query: 742 VLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAK 801
V R+SP K ++K + E +VA+TGDG ND ALK AD+G AMG GTDV+K
Sbjct: 646 VFFRTSPKHKLKIIKAL-----QESGAIVAMTGDGVNDAVALKSADIGIAMGQTGTDVSK 700
Query: 802 EASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLK 861
EA+++IL DD+FS+I+ AV G+ ++ +I F++FQL+ ++ A+ + SPL
Sbjct: 701 EAANMILVDDDFSAIMNAVEEGKGIFYNIKNFVRFQLSTSISALSLITLSTVFNLPSPLN 760
Query: 862 AVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAVYQLALI 921
A+Q+LW+N+IMD + +L EP + + P ++SR ++ IL A +I
Sbjct: 761 AMQILWINIIMDGPPAQSLGVEPVDKDAFRQPPRSVRDTILSRALILKILMSAA---III 817
Query: 922 FTLLFVGEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARKIHGERNVFD-G 980
LF+ K D + T+ F FV LFN + R + +F+ G
Sbjct: 818 SGTLFIFWKEMPED-------RASTPRTTTMTFTCFVFFDLFNALTCRS--QTKLIFEIG 868
Query: 981 IFRNPIFCTIVLGTFAIQIVIV 1002
RN +F VLG+ Q+ ++
Sbjct: 869 FLRNHMFLYSVLGSILGQLAVI 890
>gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens]
Length = 1039
Score = 278 bits (710), Expect = 3e-74
Identities = 238/784 (30%), Positives = 374/784 (47%), Gaps = 129/784 (16%)
Query: 164 VVLVTAFNDWSKEKQFRGLQSRIEQ--EQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDL 221
VV++T + +E + + S + Q+ V+R + IP ++VVGDI +VK GD
Sbjct: 154 VVILTGIFAYYQEAKSTNIMSSFNKMIPQQALVIRDSEKKTIPSEQLVVGDIVEVKGGDQ 213
Query: 222 LPADGLFIQGNDLKIDESSLTGESDQVRKSVD---KDPM-----LLSGTHVMEGSGRMLV 273
+PAD + ++D SSLTGES+ +S + ++P+ T +EG+ +V
Sbjct: 214 IPADIRVLSSQGCRVDNSSLTGESEPQPRSSEFTHENPLETKNICFYSTTCLEGTVTGMV 273
Query: 274 TAVGVNSQTGIIFTLLGAGGEEEEKKDKKAKQQDGAAAMEMQPLKSAEGGDADDRKKASM 333
G + G I +L G E+
Sbjct: 274 INTGDRTIIGHIASLASGVGNEK------------------------------------- 296
Query: 334 HKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDTFVVNKKPWLPECTPVYVQ 393
T +A++I +++ + V I +L+F + V ++
Sbjct: 297 ------------TPIAIEIEHFVHIVAGVAVSIGILFFII---------------AVSLK 329
Query: 394 YFVKFFIIGVTVLVVA-VPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAIC 452
Y V II + ++VA VPEGL VT++L+ + K+M K N LV++L+A ET+G+ + IC
Sbjct: 330 YQVLDSIIFLIGIIVANVPEGLLATVTVTLSLTAKRMAKKNCLVKNLEAVETLGSTSIIC 389
Query: 453 SDKTGTLTTNRMTVV------QAYVGDV---HYKEIPDPSSINTKTMELLINAIAINSAY 503
SDKTGTLT NRMTV Q +V D H ++ D SS ++ +I N A
Sbjct: 390 SDKTGTLTQNRMTVAHLWFDNQIFVADTSEDHSNQVFDQSSRTWASLSKIITLC--NRA- 446
Query: 504 TTKILPPEKEGALPRQ--VGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKVYTFNSVR 561
+ P ++ + ++ +G+ +E LL F + D +R + K+ ++ FNS
Sbjct: 447 --EFKPGQENVPIMKKAVIGDASETALLKFSEVILGDVMEIRKR--NRKVAEI-PFNSTN 501
Query: 562 KSMSTVIKLPD---ESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEP 618
K ++ ++ D + F M KGA E +L+KC I+ E P D+
Sbjct: 502 KFQLSIHEMDDPHGKRFLMVMKGAPERILEKCSTIMINGEE----HPLDKSTAKTFHTAY 557
Query: 619 MACDGLRT----ICVAYR---DFPSSPEPDWDNENDILNELTCICVVGIEDPVRPEVPEA 671
M GL C Y +FP + D D N + L + ++ + DP R VP+A
Sbjct: 558 MELGGLGERVLGFCHLYLPADEFPETYSFDIDAMNFPTSNLCFVGLLSMIDPPRSTVPDA 617
Query: 672 IRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPGEDF-------LCLEGKEFNRRIRN- 723
+ KC+ AGI V MVTGD+ TA+AIA GII + L + ++ N+R
Sbjct: 618 VTKCRSAGIKVIMVTGDHPITAKAIAKSVGIISANSETVEDIAHRLNIAVEQVNKRDAKA 677
Query: 724 ------EKGEIEQERIDKIWPKLR--VLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGD 775
E ++ E++D+I + V AR+SP K +V+G Q VVAVTGD
Sbjct: 678 AVVTGMELKDMSSEQLDEILANYQEIVFARTSPQQKLIIVEGC-----QRQDAVVAVTGD 732
Query: 776 GTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQ 835
G ND PALKKAD+G AMGIAG+D AK A+D++L DDNF+SIV V GR ++D++ K +
Sbjct: 733 GVNDSPALKKADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVEEGRLIFDNLKKTIA 792
Query: 836 FQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPY 895
+ LT N+ + + P+ + +L+++L D S+ALA E ++ RKP
Sbjct: 793 YSLTKNIAELCPFLIYIIVGLPLPIGTITILFIDLGTDIIPSIALAYEKAESDIMNRKPR 852
Query: 896 GRNK 899
+NK
Sbjct: 853 HKNK 856
>gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3
[Homo sapiens]
Length = 1015
Score = 276 bits (705), Expect = 1e-73
Identities = 256/890 (28%), Positives = 401/890 (45%), Gaps = 151/890 (16%)
Query: 75 LEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLGLSFYHPPGEGNEGC 134
++K K+ +G N +P ++ KT L+LV E +D+ + IL +AA IS L+++
Sbjct: 29 VKKLKERWGSNELPAEEGKTLLELVIEQFEDLLVRILLLAACISFVLAWF---------- 78
Query: 135 ATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTV 194
E+ E ++E ILL ++ +V + + + E L+ + K
Sbjct: 79 -------EEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKEYEPEMGKVYR 131
Query: 195 VRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESSLTGESDQVRKSVDK 254
V +I +IV GDI ++ G+ + I+ D D ++ + DK
Sbjct: 132 QDRKSVQRIKAKDIVPGDIVEIA-GESVSV----IKHTDPVPDPRAV---------NQDK 177
Query: 255 DPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKAKQQDGAAAMEM 314
ML SGT++ G +V A GVN++ G K +D A E
Sbjct: 178 KNMLFSGTNIAAGKAMGVVVATGVNTEIG--------------------KIRDEMVATE- 216
Query: 315 QPLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVD 374
+E++ LQ KL + Q+ K V+S I + + ++
Sbjct: 217 ---------------------QERTPLQQKLDEFGEQLSK---VISLICIAVWIINIGHF 252
Query: 375 TFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNN 434
V+ W ++ + +F I V + V A+PEGLP +T LA ++M K N
Sbjct: 253 NDPVHGGSW--------IRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNA 304
Query: 435 LVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYV----------------------- 471
+VR L + ET+G + ICSDKTGTLTTN+M+V + ++
Sbjct: 305 IVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFILDRVEGDTCSLNEFTITGSTYAP 364
Query: 472 -GDVHYKEIPDPSSINTKTMELLINAIAINSAYTTKILPPEKEGALPRQVGNKTECGLLG 530
G+VH + P +N + L+ I + L + + +VG TE L
Sbjct: 365 IGEVHKDDKP----VNCHQYDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTC 420
Query: 531 FVLDL-----------KQDYEPVRSQMPEEKLYKVYT--FNSVRKSMSTVIKLPDESFR- 576
V + K + + + ++ + K +T F+ RKSMS V P++ R
Sbjct: 421 LVEKMNVFDTELKGLSKIERANACNSVIKQLMKKEFTLEFSRDRKSMS-VYCTPNKPSRT 479
Query: 577 ----MYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMAC--DGLRTICVA 630
M+ KGA E V+ +C I G +V + + VI D LR + +A
Sbjct: 480 SMSKMFVKGAPEGVIDRCTHIR--VGSTKVPMTSGVKQKIMSVIREWGSGSDTLRCLALA 537
Query: 631 YRDFPSSPEPDW--DNENDILNE--LTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVT 686
D P E D+ N I E LT + VG+ DP R EV +++ C++AGI V M+T
Sbjct: 538 THDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMIT 597
Query: 687 GDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDKIWPKLRVLARS 746
GDN TA AI + GI ED + K F R E E+ R AR
Sbjct: 598 GDNKGTAVAICRRIGIFGQDED---VTSKAFTGR---EFDELNPSAQRDACLNARCFARV 651
Query: 747 SPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDI 806
P+ K +V+ + ++ A+TGDG ND PALKKA++G AMG +GT VAK AS++
Sbjct: 652 EPSHKSKIVEFLQSFD-----EITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEM 705
Query: 807 ILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQML 866
+L DDNFS+IV AV GR +Y+++ +F+++ ++ NV V+ F A + L VQ+L
Sbjct: 706 VLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLL 765
Query: 867 WVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAVY 916
WVNL+ D + AL PP ++ + P +PLIS + L Y
Sbjct: 766 WVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIGCY 815
>gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo
sapiens]
Length = 1023
Score = 273 bits (697), Expect = 9e-73
Identities = 245/838 (29%), Positives = 394/838 (47%), Gaps = 143/838 (17%)
Query: 138 QGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQS-RIEQEQKFTVVR 196
Q E+E + + ++ ++LS + V++ F+ + + K + ++S + Q+ V+R
Sbjct: 118 QAATEEEPQNDNLYL---GVVLSAV-VIITGCFSYYQEAKSSKIMESFKNMVPQQALVIR 173
Query: 197 AGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESSLTGESDQVRKSVD--- 253
G+ + I E+VVGD+ +VK GD +PAD I N K+D SSLTGES+ +S D
Sbjct: 174 NGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTN 233
Query: 254 KDPM-----LLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKAKQQDG 308
++P+ T+ +EG+ R +V G + G I TL
Sbjct: 234 ENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLA------------------- 274
Query: 309 AAAMEMQPLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILV 368
S L+G T +A +I +++ + V + V
Sbjct: 275 ------------------------------SGLEGGQTPIAAEIEHFIHIITGVAVFLGV 304
Query: 369 LYFTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKK 428
+F + ++ + WL F+IG+ +V VPEGL VT+ L + K+
Sbjct: 305 SFFILS--LILEYTWLEAV----------IFLIGI--IVANVPEGLLATVTVCLTLTAKR 350
Query: 429 MMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGD-VHYKEIPDPSS--- 484
M + N LV++L+A ET+G+ + ICSDKTGTLT NRMTV + + +H + + S
Sbjct: 351 MARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTENQSGVS 410
Query: 485 -INTKTMELLINAIAINSAYTTKILPPEKEGALPRQV-GNKTECGLL-------GFVLDL 535
T L ++ IA E L R V G+ +E LL G V ++
Sbjct: 411 FDKTSATWLALSRIAGLCNRAVFQANQENLPILKRAVAGDASESALLKCIELCCGSVKEM 470
Query: 536 KQDYEPVRSQMPEEKLYKVYTFNSVRKSMSTVIKLPDES---FRMYSKGASEIVLKKCCK 592
++ Y + ++P FNS K ++ K P+ S + KGA E +L +C
Sbjct: 471 RERYAKI-VEIP---------FNSTNKYQLSIHKNPNTSEPQHLLVMKGAPERILDRCSS 520
Query: 593 IL-NGAGEPRVFRPRDRDEMVKKVIEPMACD---------GLRTICVAYRDFPSSPEPDW 642
IL +G +P DE +K + + G + + FP + D
Sbjct: 521 ILLHGKEQPL-------DEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQFDT 573
Query: 643 DNENDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKCGI 702
D+ N ++ L + ++ + DP R VP+A+ KC+ AGI V MVTGD+ TA+AIA GI
Sbjct: 574 DDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGI 633
Query: 703 IHPGEDF-------LCLEGKEFNRRIR-------NEKGEIEQERIDKI--WPKLRVLARS 746
I G + L + + N R ++ ++ E++D I + V AR+
Sbjct: 634 ISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFART 693
Query: 747 SPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDI 806
SP K +V+G Q +VAVTGDG ND PALKKAD+G AMGIAG+DV+K+A+D+
Sbjct: 694 SPQQKLIIVEGC-----QRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADM 748
Query: 807 ILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQML 866
IL DDNF+SIV V GR ++D++ K + + LT N+ + PL V +L
Sbjct: 749 ILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTIL 808
Query: 867 WVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAVYQLALIFTL 924
++L D +++LA E ++ R+P P + + + ++ A Q+ +I L
Sbjct: 809 CIDLGTDMVPAISLAYEQAESDIMKRQP---RNPKTDKLVNERLISMAYGQIGMIQAL 863
>gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo
sapiens]
Length = 992
Score = 273 bits (697), Expect = 9e-73
Identities = 245/838 (29%), Positives = 394/838 (47%), Gaps = 143/838 (17%)
Query: 138 QGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQS-RIEQEQKFTVVR 196
Q E+E + + ++ ++LS + V++ F+ + + K + ++S + Q+ V+R
Sbjct: 87 QAATEEEPQNDNLYL---GVVLSAV-VIITGCFSYYQEAKSSKIMESFKNMVPQQALVIR 142
Query: 197 AGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESSLTGESDQVRKSVD--- 253
G+ + I E+VVGD+ +VK GD +PAD I N K+D SSLTGES+ +S D
Sbjct: 143 NGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTN 202
Query: 254 KDPM-----LLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKAKQQDG 308
++P+ T+ +EG+ R +V G + G I TL
Sbjct: 203 ENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLA------------------- 243
Query: 309 AAAMEMQPLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILV 368
S L+G T +A +I +++ + V + V
Sbjct: 244 ------------------------------SGLEGGQTPIAAEIEHFIHIITGVAVFLGV 273
Query: 369 LYFTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKK 428
+F + ++ + WL F+IG+ +V VPEGL VT+ L + K+
Sbjct: 274 SFFILS--LILEYTWLEAV----------IFLIGI--IVANVPEGLLATVTVCLTLTAKR 319
Query: 429 MMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGD-VHYKEIPDPSS--- 484
M + N LV++L+A ET+G+ + ICSDKTGTLT NRMTV + + +H + + S
Sbjct: 320 MARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTENQSGVS 379
Query: 485 -INTKTMELLINAIAINSAYTTKILPPEKEGALPRQV-GNKTECGLL-------GFVLDL 535
T L ++ IA E L R V G+ +E LL G V ++
Sbjct: 380 FDKTSATWLALSRIAGLCNRAVFQANQENLPILKRAVAGDASESALLKCIELCCGSVKEM 439
Query: 536 KQDYEPVRSQMPEEKLYKVYTFNSVRKSMSTVIKLPDES---FRMYSKGASEIVLKKCCK 592
++ Y + ++P FNS K ++ K P+ S + KGA E +L +C
Sbjct: 440 RERYAKI-VEIP---------FNSTNKYQLSIHKNPNTSEPQHLLVMKGAPERILDRCSS 489
Query: 593 IL-NGAGEPRVFRPRDRDEMVKKVIEPMACD---------GLRTICVAYRDFPSSPEPDW 642
IL +G +P DE +K + + G + + FP + D
Sbjct: 490 ILLHGKEQPL-------DEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQFDT 542
Query: 643 DNENDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKCGI 702
D+ N ++ L + ++ + DP R VP+A+ KC+ AGI V MVTGD+ TA+AIA GI
Sbjct: 543 DDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGI 602
Query: 703 IHPGEDF-------LCLEGKEFNRRIR-------NEKGEIEQERIDKI--WPKLRVLARS 746
I G + L + + N R ++ ++ E++D I + V AR+
Sbjct: 603 ISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFART 662
Query: 747 SPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDI 806
SP K +V+G Q +VAVTGDG ND PALKKAD+G AMGIAG+DV+K+A+D+
Sbjct: 663 SPQQKLIIVEGC-----QRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADM 717
Query: 807 ILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQML 866
IL DDNF+SIV V GR ++D++ K + + LT N+ + PL V +L
Sbjct: 718 ILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTIL 777
Query: 867 WVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAVYQLALIFTL 924
++L D +++LA E ++ R+P P + + + ++ A Q+ +I L
Sbjct: 778 CIDLGTDMVPAISLAYEQAESDIMKRQP---RNPKTDKLVNERLISMAYGQIGMIQAL 832
>gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens]
Length = 1023
Score = 273 bits (697), Expect = 9e-73
Identities = 245/838 (29%), Positives = 394/838 (47%), Gaps = 143/838 (17%)
Query: 138 QGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQS-RIEQEQKFTVVR 196
Q E+E + + ++ ++LS + V++ F+ + + K + ++S + Q+ V+R
Sbjct: 118 QAATEEEPQNDNLYL---GVVLSAV-VIITGCFSYYQEAKSSKIMESFKNMVPQQALVIR 173
Query: 197 AGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESSLTGESDQVRKSVD--- 253
G+ + I E+VVGD+ +VK GD +PAD I N K+D SSLTGES+ +S D
Sbjct: 174 NGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTN 233
Query: 254 KDPM-----LLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKAKQQDG 308
++P+ T+ +EG+ R +V G + G I TL
Sbjct: 234 ENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLA------------------- 274
Query: 309 AAAMEMQPLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILV 368
S L+G T +A +I +++ + V + V
Sbjct: 275 ------------------------------SGLEGGQTPIAAEIEHFIHIITGVAVFLGV 304
Query: 369 LYFTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKK 428
+F + ++ + WL F+IG+ +V VPEGL VT+ L + K+
Sbjct: 305 SFFILS--LILEYTWLEAV----------IFLIGI--IVANVPEGLLATVTVCLTLTAKR 350
Query: 429 MMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGD-VHYKEIPDPSS--- 484
M + N LV++L+A ET+G+ + ICSDKTGTLT NRMTV + + +H + + S
Sbjct: 351 MARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTENQSGVS 410
Query: 485 -INTKTMELLINAIAINSAYTTKILPPEKEGALPRQV-GNKTECGLL-------GFVLDL 535
T L ++ IA E L R V G+ +E LL G V ++
Sbjct: 411 FDKTSATWLALSRIAGLCNRAVFQANQENLPILKRAVAGDASESALLKCIELCCGSVKEM 470
Query: 536 KQDYEPVRSQMPEEKLYKVYTFNSVRKSMSTVIKLPDES---FRMYSKGASEIVLKKCCK 592
++ Y + ++P FNS K ++ K P+ S + KGA E +L +C
Sbjct: 471 RERYAKI-VEIP---------FNSTNKYQLSIHKNPNTSEPQHLLVMKGAPERILDRCSS 520
Query: 593 IL-NGAGEPRVFRPRDRDEMVKKVIEPMACD---------GLRTICVAYRDFPSSPEPDW 642
IL +G +P DE +K + + G + + FP + D
Sbjct: 521 ILLHGKEQPL-------DEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQFDT 573
Query: 643 DNENDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKCGI 702
D+ N ++ L + ++ + DP R VP+A+ KC+ AGI V MVTGD+ TA+AIA GI
Sbjct: 574 DDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGI 633
Query: 703 IHPGEDF-------LCLEGKEFNRRIR-------NEKGEIEQERIDKI--WPKLRVLARS 746
I G + L + + N R ++ ++ E++D I + V AR+
Sbjct: 634 ISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFART 693
Query: 747 SPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDI 806
SP K +V+G Q +VAVTGDG ND PALKKAD+G AMGIAG+DV+K+A+D+
Sbjct: 694 SPQQKLIIVEGC-----QRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADM 748
Query: 807 ILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQML 866
IL DDNF+SIV V GR ++D++ K + + LT N+ + PL V +L
Sbjct: 749 ILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTIL 808
Query: 867 WVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAVYQLALIFTL 924
++L D +++LA E ++ R+P P + + + ++ A Q+ +I L
Sbjct: 809 CIDLGTDMVPAISLAYEQAESDIMKRQP---RNPKTDKLVNERLISMAYGQIGMIQAL 863
>gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens]
Length = 1013
Score = 271 bits (694), Expect = 2e-72
Identities = 266/944 (28%), Positives = 436/944 (46%), Gaps = 155/944 (16%)
Query: 29 EELRSLMELRGTEAVVKIKETYGDTEAICRRLKTSPVEGLPGTAPDLEKRKQIFGQN--- 85
+E R L +L+ A+ + K + E +CR+ T V+GL + K ++I ++
Sbjct: 17 KERRDLDDLKKEVAMTEHKMS---VEEVCRKYNTDCVQGLTHS-----KAQEILARDGPN 68
Query: 86 -FIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLGLSFYHPPGEGNEGCATAQGGAEDE 144
PP +++ + + I+L I AI+ L++ Q G ED+
Sbjct: 69 ALTPPPTTPEWVKFCRQLFGGFS-ILLWIGAILCF-LAY------------GIQAGTEDD 114
Query: 145 GEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQS-RIEQEQKFTVVRAGQVVQI 203
+ ++ I+L+ + V++ F+ + + K + ++S + Q+ V+R G+ +Q+
Sbjct: 115 PSGDNLYL---GIVLAAV-VIITGCFSYYQEAKSSKIMESFKNMVPQQALVIREGEKMQV 170
Query: 204 PVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESSLTGESDQVRKSVD---KDPM--- 257
E+VVGD+ ++K GD +PAD I + K+D SSLTGES+ +S D +P+
Sbjct: 171 NAEEVVVGDLVEIKGGDRVPADLRIISAHGCKVDNSSLTGESEPQTRSPDCTHDNPLETR 230
Query: 258 --LLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKAKQQDGAAAMEMQ 315
T+ +EG+ R +V A G + G I TL A+ +E+
Sbjct: 231 NITFFSTNCVEGTARGVVVATGDRTVMGRIATL--------------------ASGLEV- 269
Query: 316 PLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDT 375
GK T +A++I +++ + V + V +F +
Sbjct: 270 ---------------------------GK-TPIAIEIEHFIQLITGVAVFLGVSFFILS- 300
Query: 376 FVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNL 435
++ WL F+IG+ +V VPEGL VT+ L + K+M + N L
Sbjct: 301 -LILGYTWLEAV----------IFLIGI--IVANVPEGLLATVTVCLTLTAKRMARKNCL 347
Query: 436 VRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGD-VHYKEIPDPSSINT--KTMEL 492
V++L+A ET+G+ + ICSDKTGTLT NRMTV + + +H + + S + K+
Sbjct: 348 VKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGTSFDKSSHT 407
Query: 493 LINAIAINSAYTTKILPPEKEG--ALPRQV-GNKTECGLLGFVLDLKQDYEPVRSQMPEE 549
+ I + ++ L R V G+ +E LL + + V+
Sbjct: 408 WVALSHIAGLCNRAVFKGGQDNIPVLKRDVAGDASESALLKCI---ELSSGSVKLMRERN 464
Query: 550 KLYKVYTFNSVRKSMSTVIKLPDESFRMY---SKGASEIVLKKCCKIL-NGAGEPRVFRP 605
K FNS K ++ + D + Y KGA E +L +C IL G +P
Sbjct: 465 KKVAEIPFNSTNKYQLSIHETEDPNDNRYLLVMKGAPERILDRCSTILLQGKEQPL---- 520
Query: 606 RDRDEMVKKVIEPMACD----GLRTI--CVAY---RDFPSSPEPDWDNENDILNELTCIC 656
DE +K+ + + G R + C Y FP D D+ N + L +
Sbjct: 521 ---DEEMKEAFQNAYLELGGLGERVLGFCHYYLPEEQFPKGFAFDCDDVNFTTDNLCFVG 577
Query: 657 VVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKE 716
++ + DP R VP+A+ KC+ AGI V MVTGD+ TA+AIA GII G + +
Sbjct: 578 LMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAAR 637
Query: 717 FNRRI-----RNEKG---------EIEQERIDKIWPKLR--VLARSSPTDKHTLVKGIID 760
N + R+ K + E+ID+I V AR+SP K +V+G
Sbjct: 638 LNIPVSQVNPRDAKACVIHGTDLKDFTSEQIDEILQNHTEIVFARTSPQQKLIIVEGC-- 695
Query: 761 STHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAV 820
Q +VAVTGDG ND PALKKAD+G AMGIAG+DV+K+A+D+IL DDNF+SIV V
Sbjct: 696 ---QRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGV 752
Query: 821 MWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLAL 880
GR ++D++ K + + LT N+ + PL + +L ++L D +++L
Sbjct: 753 EEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIMANIPLPLGTITILCIDLGTDMVPAISL 812
Query: 881 ATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAVYQLALIFTL 924
A E ++ R+P P + + + ++ A Q+ +I L
Sbjct: 813 AYEAAESDIMKRQP---RNPRTDKLVNERLISMAYGQIGMIQAL 853
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,339,726
Number of Sequences: 37866
Number of extensions: 2073275
Number of successful extensions: 7342
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 72
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 6958
Number of HSP's gapped (non-prelim): 238
length of query: 1198
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1084
effective length of database: 13,930,794
effective search space: 15100980696
effective search space used: 15100980696
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.