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Search of human proteins with 13186241
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13186241 fibroblast growth factor receptor 1 isoform 6
precursor [Homo sapiens]
(300 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13186241 fibroblast growth factor receptor 1 isoform 6 precur... 627 e-180
gi|13186238 fibroblast growth factor receptor 1 isoform 5 precur... 622 e-178
gi|13186236 fibroblast growth factor receptor 1 isoform 4 precur... 471 e-133
gi|13186234 fibroblast growth factor receptor 1 isoform 3 precur... 466 e-131
gi|13186251 fibroblast growth factor receptor 1 isoform 2 precur... 405 e-113
gi|13186249 fibroblast growth factor receptor 1 isoform 9 precur... 400 e-111
gi|105990522 fibroblast growth factor receptor 1 isoform 1 precu... 400 e-111
gi|222144244 fibroblast growth factor receptor 2 isoform 9 precu... 310 8e-85
gi|222144235 fibroblast growth factor receptor 2 isoform 5 precu... 310 8e-85
gi|222144239 fibroblast growth factor receptor 2 isoform 7 precu... 298 4e-81
gi|222144231 fibroblast growth factor receptor 2 isoform 3 precu... 296 1e-80
gi|221316639 fibroblast growth factor receptor 2 isoform 1 precu... 296 1e-80
gi|221316638 fibroblast growth factor receptor 2 isoform 2 precu... 296 1e-80
gi|222144241 fibroblast growth factor receptor 2 isoform 8 precu... 289 2e-78
gi|222144237 fibroblast growth factor receptor 2 isoform 6 precu... 289 2e-78
gi|13112048 fibroblast growth factor receptor 3 isoform 2 precur... 278 3e-75
gi|4503711 fibroblast growth factor receptor 3 isoform 1 precurs... 277 7e-75
gi|254028242 fibroblast growth factor receptor 3 isoform 3 precu... 277 9e-75
gi|47524177 fibroblast growth factor receptor 4 isoform 2 precur... 259 3e-69
gi|47524175 fibroblast growth factor receptor 4 isoform 1 precur... 259 3e-69
gi|47524173 fibroblast growth factor receptor 4 isoform 1 precur... 259 3e-69
gi|222144233 fibroblast growth factor receptor 2 isoform 4 precu... 191 9e-49
gi|51988914 fibroblast growth factor receptor-like 1 precursor [... 120 1e-27
gi|51988910 fibroblast growth factor receptor-like 1 precursor [... 120 1e-27
gi|51988912 fibroblast growth factor receptor-like 1 precursor [... 120 1e-27
gi|142976733 surface glycoprotein, Ig superfamily member [Homo s... 74 2e-13
gi|118572606 hemicentin 1 [Homo sapiens] 73 3e-13
gi|7657359 contactin 5 isoform long [Homo sapiens] 70 3e-12
gi|28373129 contactin 5 isoform short [Homo sapiens] 70 3e-12
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 69 7e-12
>gi|13186241 fibroblast growth factor receptor 1 isoform 6 precursor
[Homo sapiens]
Length = 300
Score = 627 bits (1616), Expect = e-180
Identities = 300/300 (100%), Positives = 300/300 (100%)
Query: 1 MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNPV 60
MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNPV
Sbjct: 1 MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNPV 60
Query: 61 APYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYA 120
APYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYA
Sbjct: 61 APYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYA 120
Query: 121 TWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGS 180
TWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGS
Sbjct: 121 TWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGS 180
Query: 181 NVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKVIMAPVFVGQSTGKETTVS 240
NVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKVIMAPVFVGQSTGKETTVS
Sbjct: 181 NVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKVIMAPVFVGQSTGKETTVS 240
Query: 241 GAQVPVGRLSCPRMGSFLTLQAHTLHLSRDLATSPRTSNRGHKVEVSWEQRAAGMGGAGL 300
GAQVPVGRLSCPRMGSFLTLQAHTLHLSRDLATSPRTSNRGHKVEVSWEQRAAGMGGAGL
Sbjct: 241 GAQVPVGRLSCPRMGSFLTLQAHTLHLSRDLATSPRTSNRGHKVEVSWEQRAAGMGGAGL 300
>gi|13186238 fibroblast growth factor receptor 1 isoform 5 precursor
[Homo sapiens]
Length = 302
Score = 622 bits (1603), Expect = e-178
Identities = 300/302 (99%), Positives = 300/302 (99%), Gaps = 2/302 (0%)
Query: 1 MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPN-- 58
MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPN
Sbjct: 1 MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNRM 60
Query: 59 PVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVR 118
PVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVR
Sbjct: 61 PVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVR 120
Query: 119 YATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVAL 178
YATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVAL
Sbjct: 121 YATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVAL 180
Query: 179 GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKVIMAPVFVGQSTGKETT 238
GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKVIMAPVFVGQSTGKETT
Sbjct: 181 GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKVIMAPVFVGQSTGKETT 240
Query: 239 VSGAQVPVGRLSCPRMGSFLTLQAHTLHLSRDLATSPRTSNRGHKVEVSWEQRAAGMGGA 298
VSGAQVPVGRLSCPRMGSFLTLQAHTLHLSRDLATSPRTSNRGHKVEVSWEQRAAGMGGA
Sbjct: 241 VSGAQVPVGRLSCPRMGSFLTLQAHTLHLSRDLATSPRTSNRGHKVEVSWEQRAAGMGGA 300
Query: 299 GL 300
GL
Sbjct: 301 GL 302
>gi|13186236 fibroblast growth factor receptor 1 isoform 4 precursor
[Homo sapiens]
Length = 731
Score = 471 bits (1211), Expect = e-133
Identities = 221/221 (100%), Positives = 221/221 (100%)
Query: 1 MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNPV 60
MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNPV
Sbjct: 1 MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNPV 60
Query: 61 APYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYA 120
APYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYA
Sbjct: 61 APYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYA 120
Query: 121 TWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGS 180
TWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGS
Sbjct: 121 TWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGS 180
Query: 181 NVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILK 221
NVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILK
Sbjct: 181 NVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILK 221
Score = 43.1 bits (100), Expect = 3e-04
Identities = 31/106 (29%), Positives = 46/106 (43%), Gaps = 18/106 (16%)
Query: 77 VPAAKTV------KFKCPSSGTPNPTLRWLK----NGKEFKPDH-------RIGGYKVRY 119
+PA KTV +F C P P ++WLK NG + PD+ + G
Sbjct: 170 LPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTD 229
Query: 120 ATWSII-MDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRP 164
++ + +V D G YTC+ N G +H+ L V+E RP
Sbjct: 230 KEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERP 275
>gi|13186234 fibroblast growth factor receptor 1 isoform 3 precursor
[Homo sapiens]
Length = 733
Score = 466 bits (1198), Expect = e-131
Identities = 221/223 (99%), Positives = 221/223 (99%), Gaps = 2/223 (0%)
Query: 1 MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPN-- 58
MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPN
Sbjct: 1 MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNRM 60
Query: 59 PVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVR 118
PVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVR
Sbjct: 61 PVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVR 120
Query: 119 YATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVAL 178
YATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVAL
Sbjct: 121 YATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVAL 180
Query: 179 GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILK 221
GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILK
Sbjct: 181 GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILK 223
Score = 43.1 bits (100), Expect = 3e-04
Identities = 31/106 (29%), Positives = 46/106 (43%), Gaps = 18/106 (16%)
Query: 77 VPAAKTV------KFKCPSSGTPNPTLRWLK----NGKEFKPDH-------RIGGYKVRY 119
+PA KTV +F C P P ++WLK NG + PD+ + G
Sbjct: 172 LPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTD 231
Query: 120 ATWSII-MDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRP 164
++ + +V D G YTC+ N G +H+ L V+E RP
Sbjct: 232 KEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERP 277
>gi|13186251 fibroblast growth factor receptor 1 isoform 2 precursor
[Homo sapiens]
Length = 820
Score = 405 bits (1040), Expect = e-113
Identities = 191/191 (100%), Positives = 191/191 (100%)
Query: 31 DALPSSEDDDDDDDSSSEEKETDNTKPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSS 90
DALPSSEDDDDDDDSSSEEKETDNTKPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSS
Sbjct: 120 DALPSSEDDDDDDDSSSEEKETDNTKPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSS 179
Query: 91 GTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINH 150
GTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINH
Sbjct: 180 GTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINH 239
Query: 151 TYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIG 210
TYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIG
Sbjct: 240 TYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIG 299
Query: 211 PDNLPYVQILK 221
PDNLPYVQILK
Sbjct: 300 PDNLPYVQILK 310
Score = 86.7 bits (213), Expect = 2e-17
Identities = 67/241 (27%), Positives = 94/241 (39%), Gaps = 70/241 (29%)
Query: 1 MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNPV 60
MWSWKCLLFWAVLVTATLCTARPSPTLPEQ
Sbjct: 1 MWSWKCLLFWAVLVTATLCTARPSPTLPEQ------------------------------ 30
Query: 61 APYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYA 120
A W +P ++E L V ++ +C ++ WL++G + +R R
Sbjct: 31 AQPWGAPVEVESFL--VHPGDLLQLRCRLRDDVQ-SINWLRDGVQLAESNR-----TRIT 82
Query: 121 TWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPH------------------ 162
+ + VP+D G Y C+ + GS + ++V + P
Sbjct: 83 GEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETD 142
Query: 163 ----RPILQAGLPANK------TVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPD 212
P+ K V V+F C P P ++WLK NG + PD
Sbjct: 143 NTKPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLK----NGKEFKPD 198
Query: 213 N 213
+
Sbjct: 199 H 199
Score = 43.1 bits (100), Expect = 3e-04
Identities = 31/106 (29%), Positives = 46/106 (43%), Gaps = 18/106 (16%)
Query: 77 VPAAKTV------KFKCPSSGTPNPTLRWLK----NGKEFKPDH-------RIGGYKVRY 119
+PA KTV +F C P P ++WLK NG + PD+ + G
Sbjct: 259 LPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTD 318
Query: 120 ATWSII-MDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRP 164
++ + +V D G YTC+ N G +H+ L V+E RP
Sbjct: 319 KEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERP 364
>gi|13186249 fibroblast growth factor receptor 1 isoform 9 precursor
[Homo sapiens]
Length = 785
Score = 400 bits (1027), Expect = e-111
Identities = 191/193 (98%), Positives = 191/193 (98%), Gaps = 2/193 (1%)
Query: 31 DALPSSEDDDDDDDSSSEEKETDNTKPN--PVAPYWTSPEKMEKKLHAVPAAKTVKFKCP 88
DALPSSEDDDDDDDSSSEEKETDNTKPN PVAPYWTSPEKMEKKLHAVPAAKTVKFKCP
Sbjct: 120 DALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCP 179
Query: 89 SSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSI 148
SSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSI
Sbjct: 180 SSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSI 239
Query: 149 NHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSK 208
NHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSK
Sbjct: 240 NHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSK 299
Query: 209 IGPDNLPYVQILK 221
IGPDNLPYVQILK
Sbjct: 300 IGPDNLPYVQILK 312
Score = 85.9 bits (211), Expect = 4e-17
Identities = 67/243 (27%), Positives = 94/243 (38%), Gaps = 72/243 (29%)
Query: 1 MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNPV 60
MWSWKCLLFWAVLVTATLCTARPSPTLPEQ
Sbjct: 1 MWSWKCLLFWAVLVTATLCTARPSPTLPEQ------------------------------ 30
Query: 61 APYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYA 120
A W +P ++E L V ++ +C ++ WL++G + +R R
Sbjct: 31 AQPWGAPVEVESFL--VHPGDLLQLRCRLRDDVQ-SINWLRDGVQLAESNR-----TRIT 82
Query: 121 TWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSP------------------- 161
+ + VP+D G Y C+ + GS + ++V + P
Sbjct: 83 GEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETD 142
Query: 162 -----HRPILQAGLPANK------TVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIG 210
P+ K V V+F C P P ++WLK NG +
Sbjct: 143 NTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLK----NGKEFK 198
Query: 211 PDN 213
PD+
Sbjct: 199 PDH 201
Score = 43.1 bits (100), Expect = 3e-04
Identities = 31/106 (29%), Positives = 46/106 (43%), Gaps = 18/106 (16%)
Query: 77 VPAAKTV------KFKCPSSGTPNPTLRWLK----NGKEFKPDH-------RIGGYKVRY 119
+PA KTV +F C P P ++WLK NG + PD+ + G
Sbjct: 261 LPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTD 320
Query: 120 ATWSII-MDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRP 164
++ + +V D G YTC+ N G +H+ L V+E RP
Sbjct: 321 KEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERP 366
>gi|105990522 fibroblast growth factor receptor 1 isoform 1
precursor [Homo sapiens]
Length = 822
Score = 400 bits (1027), Expect = e-111
Identities = 191/193 (98%), Positives = 191/193 (98%), Gaps = 2/193 (1%)
Query: 31 DALPSSEDDDDDDDSSSEEKETDNTKPN--PVAPYWTSPEKMEKKLHAVPAAKTVKFKCP 88
DALPSSEDDDDDDDSSSEEKETDNTKPN PVAPYWTSPEKMEKKLHAVPAAKTVKFKCP
Sbjct: 120 DALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCP 179
Query: 89 SSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSI 148
SSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSI
Sbjct: 180 SSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSI 239
Query: 149 NHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSK 208
NHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSK
Sbjct: 240 NHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSK 299
Query: 209 IGPDNLPYVQILK 221
IGPDNLPYVQILK
Sbjct: 300 IGPDNLPYVQILK 312
Score = 85.9 bits (211), Expect = 4e-17
Identities = 67/243 (27%), Positives = 94/243 (38%), Gaps = 72/243 (29%)
Query: 1 MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNPV 60
MWSWKCLLFWAVLVTATLCTARPSPTLPEQ
Sbjct: 1 MWSWKCLLFWAVLVTATLCTARPSPTLPEQ------------------------------ 30
Query: 61 APYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYA 120
A W +P ++E L V ++ +C ++ WL++G + +R R
Sbjct: 31 AQPWGAPVEVESFL--VHPGDLLQLRCRLRDDVQ-SINWLRDGVQLAESNR-----TRIT 82
Query: 121 TWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSP------------------- 161
+ + VP+D G Y C+ + GS + ++V + P
Sbjct: 83 GEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETD 142
Query: 162 -----HRPILQAGLPANK------TVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIG 210
P+ K V V+F C P P ++WLK NG +
Sbjct: 143 NTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLK----NGKEFK 198
Query: 211 PDN 213
PD+
Sbjct: 199 PDH 201
Score = 43.1 bits (100), Expect = 3e-04
Identities = 31/106 (29%), Positives = 46/106 (43%), Gaps = 18/106 (16%)
Query: 77 VPAAKTV------KFKCPSSGTPNPTLRWLK----NGKEFKPDH-------RIGGYKVRY 119
+PA KTV +F C P P ++WLK NG + PD+ + G
Sbjct: 261 LPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTD 320
Query: 120 ATWSII-MDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRP 164
++ + +V D G YTC+ N G +H+ L V+E RP
Sbjct: 321 KEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERP 366
>gi|222144244 fibroblast growth factor receptor 2 isoform 9
precursor [Homo sapiens]
Length = 680
Score = 310 bits (795), Expect = 8e-85
Identities = 148/227 (65%), Positives = 173/227 (76%), Gaps = 9/227 (3%)
Query: 1 MWSWKCLLFWAVLVTATLCTARPS------PTLPEQDALPSSEDDDDDDDSSSEEKETDN 54
M SW + V+ ATL ARPS TL +DA+ S +D+DD D + E N
Sbjct: 1 MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEDAISSGDDEDDTDGAEDFVSENSN 60
Query: 55 TKPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGG 114
K APYWT+ EKMEK+LHAVPAA TVKF+CP+ G P PT+RWLKNGKEFK +HRIGG
Sbjct: 61 NKR---APYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGG 117
Query: 115 YKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANK 174
YKVR WS+IM+SVVPSDKGNYTC+VENEYGSINHTY LDVVERSPHRPILQAGLPAN
Sbjct: 118 YKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANA 177
Query: 175 TVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILK 221
+ +G +VEF+CKVYSD QPHIQW+KH+E NGSK GPD LPY+++LK
Sbjct: 178 STVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLK 224
Score = 31.2 bits (69), Expect = 1.2
Identities = 23/88 (26%), Positives = 37/88 (42%), Gaps = 12/88 (13%)
Query: 83 VKFKCPSSGTPNPTLRWLK----NGKEFKPDH-------RIGGYKVRYATWSIIMDSVVP 131
V+F C P ++W+K NG ++ PD + G A + + +V
Sbjct: 185 VEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAE-VLALFNVTE 243
Query: 132 SDKGNYTCIVENEYGSINHTYQLDVVER 159
+D G Y C V N G N + L V+ +
Sbjct: 244 ADAGEYICKVSNYIGQANQSAWLTVLPK 271
>gi|222144235 fibroblast growth factor receptor 2 isoform 5
precursor [Homo sapiens]
Length = 707
Score = 310 bits (795), Expect = 8e-85
Identities = 148/227 (65%), Positives = 173/227 (76%), Gaps = 9/227 (3%)
Query: 1 MWSWKCLLFWAVLVTATLCTARPS------PTLPEQDALPSSEDDDDDDDSSSEEKETDN 54
M SW + V+ ATL ARPS TL +DA+ S +D+DD D + E N
Sbjct: 1 MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEDAISSGDDEDDTDGAEDFVSENSN 60
Query: 55 TKPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGG 114
K APYWT+ EKMEK+LHAVPAA TVKF+CP+ G P PT+RWLKNGKEFK +HRIGG
Sbjct: 61 NKR---APYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGG 117
Query: 115 YKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANK 174
YKVR WS+IM+SVVPSDKGNYTC+VENEYGSINHTY LDVVERSPHRPILQAGLPAN
Sbjct: 118 YKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANA 177
Query: 175 TVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILK 221
+ +G +VEF+CKVYSD QPHIQW+KH+E NGSK GPD LPY+++LK
Sbjct: 178 STVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLK 224
Score = 30.8 bits (68), Expect = 1.5
Identities = 22/87 (25%), Positives = 36/87 (41%), Gaps = 12/87 (13%)
Query: 83 VKFKCPSSGTPNPTLRWLK----NGKEFKPDH-------RIGGYKVRYATWSII-MDSVV 130
V+F C P ++W+K NG ++ PD + G ++ + +V
Sbjct: 185 VEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVT 244
Query: 131 PSDKGNYTCIVENEYGSINHTYQLDVV 157
D G YTC+ N G H+ L V+
Sbjct: 245 FEDAGEYTCLAGNSIGISFHSAWLTVL 271
>gi|222144239 fibroblast growth factor receptor 2 isoform 7
precursor [Homo sapiens]
Length = 705
Score = 298 bits (763), Expect = 4e-81
Identities = 136/192 (70%), Positives = 158/192 (82%), Gaps = 3/192 (1%)
Query: 31 DALPSSEDDDDDDDSSSEEKETDNTKPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSS 90
DA+ S +D+DD D + E N K APYWT+ EKMEK+LHAVPAA TVKF+CP+
Sbjct: 126 DAISSGDDEDDTDGAEDFVSENSNNKR---APYWTNTEKMEKRLHAVPAANTVKFRCPAG 182
Query: 91 GTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINH 150
G P PT+RWLKNGKEFK +HRIGGYKVR WS+IM+SVVPSDKGNYTC+VENEYGSINH
Sbjct: 183 GNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINH 242
Query: 151 TYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIG 210
TY LDVVERSPHRPILQAGLPAN + +G +VEF+CKVYSD QPHIQW+KH+E NGSK G
Sbjct: 243 TYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYG 302
Query: 211 PDNLPYVQILKV 222
PD LPY+++LKV
Sbjct: 303 PDGLPYLKVLKV 314
Score = 35.4 bits (80), Expect = 0.062
Identities = 45/229 (19%), Positives = 76/229 (33%), Gaps = 63/229 (27%)
Query: 1 MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNPV 60
M SW + V+ ATL ARPS +L E L E P
Sbjct: 1 MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEE---------------------PP 39
Query: 61 APYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHR---IGGYKV 117
Y S + +++ ++++ +C + W K+G P++R IG Y
Sbjct: 40 TKYQIS----QPEVYVAAPGESLEVRCLLKDA--AVISWTKDGVHLGPNNRTVLIGEY-- 91
Query: 118 RYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVE------------------- 158
+ + P D G Y C S + ++V +
Sbjct: 92 ------LQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVS 145
Query: 159 ------RSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKH 201
R+P+ + V + V+F C +P P ++WLK+
Sbjct: 146 ENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKN 194
>gi|222144231 fibroblast growth factor receptor 2 isoform 3
precursor [Homo sapiens]
Length = 769
Score = 296 bits (759), Expect = 1e-80
Identities = 135/191 (70%), Positives = 157/191 (82%), Gaps = 3/191 (1%)
Query: 31 DALPSSEDDDDDDDSSSEEKETDNTKPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSS 90
DA+ S +D+DD D + E N K APYWT+ EKMEK+LHAVPAA TVKF+CP+
Sbjct: 126 DAISSGDDEDDTDGAEDFVSENSNNKR---APYWTNTEKMEKRLHAVPAANTVKFRCPAG 182
Query: 91 GTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINH 150
G P PT+RWLKNGKEFK +HRIGGYKVR WS+IM+SVVPSDKGNYTC+VENEYGSINH
Sbjct: 183 GNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINH 242
Query: 151 TYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIG 210
TY LDVVERSPHRPILQAGLPAN + +G +VEF+CKVYSD QPHIQW+KH+E NGSK G
Sbjct: 243 TYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYG 302
Query: 211 PDNLPYVQILK 221
PD LPY+++LK
Sbjct: 303 PDGLPYLKVLK 313
Score = 35.4 bits (80), Expect = 0.062
Identities = 45/229 (19%), Positives = 76/229 (33%), Gaps = 63/229 (27%)
Query: 1 MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNPV 60
M SW + V+ ATL ARPS +L E L E P
Sbjct: 1 MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEE---------------------PP 39
Query: 61 APYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHR---IGGYKV 117
Y S + +++ ++++ +C + W K+G P++R IG Y
Sbjct: 40 TKYQIS----QPEVYVAAPGESLEVRCLLKDA--AVISWTKDGVHLGPNNRTVLIGEY-- 91
Query: 118 RYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVE------------------- 158
+ + P D G Y C S + ++V +
Sbjct: 92 ------LQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVS 145
Query: 159 ------RSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKH 201
R+P+ + V + V+F C +P P ++WLK+
Sbjct: 146 ENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKN 194
Score = 31.2 bits (69), Expect = 1.2
Identities = 23/88 (26%), Positives = 37/88 (42%), Gaps = 12/88 (13%)
Query: 83 VKFKCPSSGTPNPTLRWLK----NGKEFKPDH-------RIGGYKVRYATWSIIMDSVVP 131
V+F C P ++W+K NG ++ PD + G A + + +V
Sbjct: 274 VEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAE-VLALFNVTE 332
Query: 132 SDKGNYTCIVENEYGSINHTYQLDVVER 159
+D G Y C V N G N + L V+ +
Sbjct: 333 ADAGEYICKVSNYIGQANQSAWLTVLPK 360
>gi|221316639 fibroblast growth factor receptor 2 isoform 1
precursor [Homo sapiens]
Length = 821
Score = 296 bits (759), Expect = 1e-80
Identities = 135/191 (70%), Positives = 157/191 (82%), Gaps = 3/191 (1%)
Query: 31 DALPSSEDDDDDDDSSSEEKETDNTKPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSS 90
DA+ S +D+DD D + E N K APYWT+ EKMEK+LHAVPAA TVKF+CP+
Sbjct: 126 DAISSGDDEDDTDGAEDFVSENSNNKR---APYWTNTEKMEKRLHAVPAANTVKFRCPAG 182
Query: 91 GTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINH 150
G P PT+RWLKNGKEFK +HRIGGYKVR WS+IM+SVVPSDKGNYTC+VENEYGSINH
Sbjct: 183 GNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINH 242
Query: 151 TYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIG 210
TY LDVVERSPHRPILQAGLPAN + +G +VEF+CKVYSD QPHIQW+KH+E NGSK G
Sbjct: 243 TYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYG 302
Query: 211 PDNLPYVQILK 221
PD LPY+++LK
Sbjct: 303 PDGLPYLKVLK 313
Score = 35.4 bits (80), Expect = 0.062
Identities = 45/229 (19%), Positives = 76/229 (33%), Gaps = 63/229 (27%)
Query: 1 MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNPV 60
M SW + V+ ATL ARPS +L E L E P
Sbjct: 1 MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEE---------------------PP 39
Query: 61 APYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHR---IGGYKV 117
Y S + +++ ++++ +C + W K+G P++R IG Y
Sbjct: 40 TKYQIS----QPEVYVAAPGESLEVRCLLKDA--AVISWTKDGVHLGPNNRTVLIGEY-- 91
Query: 118 RYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVE------------------- 158
+ + P D G Y C S + ++V +
Sbjct: 92 ------LQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVS 145
Query: 159 ------RSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKH 201
R+P+ + V + V+F C +P P ++WLK+
Sbjct: 146 ENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKN 194
Score = 30.8 bits (68), Expect = 1.5
Identities = 22/87 (25%), Positives = 36/87 (41%), Gaps = 12/87 (13%)
Query: 83 VKFKCPSSGTPNPTLRWLK----NGKEFKPDH-------RIGGYKVRYATWSII-MDSVV 130
V+F C P ++W+K NG ++ PD + G ++ + +V
Sbjct: 274 VEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVT 333
Query: 131 PSDKGNYTCIVENEYGSINHTYQLDVV 157
D G YTC+ N G H+ L V+
Sbjct: 334 FEDAGEYTCLAGNSIGISFHSAWLTVL 360
>gi|221316638 fibroblast growth factor receptor 2 isoform 2
precursor [Homo sapiens]
Length = 822
Score = 296 bits (759), Expect = 1e-80
Identities = 135/191 (70%), Positives = 157/191 (82%), Gaps = 3/191 (1%)
Query: 31 DALPSSEDDDDDDDSSSEEKETDNTKPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSS 90
DA+ S +D+DD D + E N K APYWT+ EKMEK+LHAVPAA TVKF+CP+
Sbjct: 126 DAISSGDDEDDTDGAEDFVSENSNNKR---APYWTNTEKMEKRLHAVPAANTVKFRCPAG 182
Query: 91 GTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINH 150
G P PT+RWLKNGKEFK +HRIGGYKVR WS+IM+SVVPSDKGNYTC+VENEYGSINH
Sbjct: 183 GNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINH 242
Query: 151 TYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIG 210
TY LDVVERSPHRPILQAGLPAN + +G +VEF+CKVYSD QPHIQW+KH+E NGSK G
Sbjct: 243 TYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYG 302
Query: 211 PDNLPYVQILK 221
PD LPY+++LK
Sbjct: 303 PDGLPYLKVLK 313
Score = 35.4 bits (80), Expect = 0.062
Identities = 45/229 (19%), Positives = 76/229 (33%), Gaps = 63/229 (27%)
Query: 1 MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNPV 60
M SW + V+ ATL ARPS +L E L E P
Sbjct: 1 MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEE---------------------PP 39
Query: 61 APYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHR---IGGYKV 117
Y S + +++ ++++ +C + W K+G P++R IG Y
Sbjct: 40 TKYQIS----QPEVYVAAPGESLEVRCLLKDA--AVISWTKDGVHLGPNNRTVLIGEY-- 91
Query: 118 RYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVE------------------- 158
+ + P D G Y C S + ++V +
Sbjct: 92 ------LQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVS 145
Query: 159 ------RSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKH 201
R+P+ + V + V+F C +P P ++WLK+
Sbjct: 146 ENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKN 194
Score = 31.2 bits (69), Expect = 1.2
Identities = 23/88 (26%), Positives = 37/88 (42%), Gaps = 12/88 (13%)
Query: 83 VKFKCPSSGTPNPTLRWLK----NGKEFKPDH-------RIGGYKVRYATWSIIMDSVVP 131
V+F C P ++W+K NG ++ PD + G A + + +V
Sbjct: 274 VEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAE-VLALFNVTE 332
Query: 132 SDKGNYTCIVENEYGSINHTYQLDVVER 159
+D G Y C V N G N + L V+ +
Sbjct: 333 ADAGEYICKVSNYIGQANQSAWLTVLPK 360
>gi|222144241 fibroblast growth factor receptor 2 isoform 8
precursor [Homo sapiens]
Length = 704
Score = 289 bits (739), Expect = 2e-78
Identities = 140/221 (63%), Positives = 161/221 (72%), Gaps = 23/221 (10%)
Query: 1 MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNPV 60
M SW + V+ ATL ARPS +L E D T
Sbjct: 1 MVSWGRFICLVVVTMATLSLARPSFSLVE-----------------------DTTLEPEG 37
Query: 61 APYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYA 120
APYWT+ EKMEK+LHAVPAA TVKF+CP+ G P PT+RWLKNGKEFK +HRIGGYKVR
Sbjct: 38 APYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQ 97
Query: 121 TWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGS 180
WS+IM+SVVPSDKGNYTC+VENEYGSINHTY LDVVERSPHRPILQAGLPAN + +G
Sbjct: 98 HWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGG 157
Query: 181 NVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILK 221
+VEF+CKVYSD QPHIQW+KH+E NGSK GPD LPY+++LK
Sbjct: 158 DVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLK 198
Score = 30.8 bits (68), Expect = 1.5
Identities = 22/87 (25%), Positives = 36/87 (41%), Gaps = 12/87 (13%)
Query: 83 VKFKCPSSGTPNPTLRWLK----NGKEFKPDH-------RIGGYKVRYATWSII-MDSVV 130
V+F C P ++W+K NG ++ PD + G ++ + +V
Sbjct: 159 VEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVT 218
Query: 131 PSDKGNYTCIVENEYGSINHTYQLDVV 157
D G YTC+ N G H+ L V+
Sbjct: 219 FEDAGEYTCLAGNSIGISFHSAWLTVL 245
>gi|222144237 fibroblast growth factor receptor 2 isoform 6
precursor [Homo sapiens]
Length = 706
Score = 289 bits (739), Expect = 2e-78
Identities = 140/221 (63%), Positives = 161/221 (72%), Gaps = 23/221 (10%)
Query: 1 MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNPV 60
M SW + V+ ATL ARPS +L E D T
Sbjct: 1 MVSWGRFICLVVVTMATLSLARPSFSLVE-----------------------DTTLEPEG 37
Query: 61 APYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYA 120
APYWT+ EKMEK+LHAVPAA TVKF+CP+ G P PT+RWLKNGKEFK +HRIGGYKVR
Sbjct: 38 APYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQ 97
Query: 121 TWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGS 180
WS+IM+SVVPSDKGNYTC+VENEYGSINHTY LDVVERSPHRPILQAGLPAN + +G
Sbjct: 98 HWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGG 157
Query: 181 NVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILK 221
+VEF+CKVYSD QPHIQW+KH+E NGSK GPD LPY+++LK
Sbjct: 158 DVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLK 198
Score = 30.8 bits (68), Expect = 1.5
Identities = 22/87 (25%), Positives = 36/87 (41%), Gaps = 12/87 (13%)
Query: 83 VKFKCPSSGTPNPTLRWLK----NGKEFKPDH-------RIGGYKVRYATWSII-MDSVV 130
V+F C P ++W+K NG ++ PD + G ++ + +V
Sbjct: 159 VEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVT 218
Query: 131 PSDKGNYTCIVENEYGSINHTYQLDVV 157
D G YTC+ N G H+ L V+
Sbjct: 219 FEDAGEYTCLAGNSIGISFHSAWLTVL 245
>gi|13112048 fibroblast growth factor receptor 3 isoform 2 precursor
[Homo sapiens]
Length = 694
Score = 278 bits (712), Expect = 3e-75
Identities = 125/189 (66%), Positives = 156/189 (82%), Gaps = 6/189 (3%)
Query: 34 PSSEDDDDDDDSSSEEKETDNTKPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTP 93
PSS DD+D +D E ++T + APYWT PE+M+KKL AVPAA TV+F+CP++G P
Sbjct: 129 PSSGDDEDGED------EAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNP 182
Query: 94 NPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQ 153
P++ WLKNG+EF+ +HRIGG K+R+ WS++M+SVVPSD+GNYTC+VEN++GSI TY
Sbjct: 183 TPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYT 242
Query: 154 LDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDN 213
LDV+ERSPHRPILQAGLPAN+T LGS+VEF CKVYSD QPHIQWLKH+EVNGSK+GPD
Sbjct: 243 LDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDG 302
Query: 214 LPYVQILKV 222
PYV +LKV
Sbjct: 303 TPYVTVLKV 311
>gi|4503711 fibroblast growth factor receptor 3 isoform 1 precursor
[Homo sapiens]
Length = 806
Score = 277 bits (709), Expect = 7e-75
Identities = 129/206 (62%), Positives = 161/206 (78%), Gaps = 11/206 (5%)
Query: 34 PSSEDDDDDDDSSSEEKETDNTKPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTP 93
PSS DD+D +D E ++T + APYWT PE+M+KKL AVPAA TV+F+CP++G P
Sbjct: 129 PSSGDDEDGED------EAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNP 182
Query: 94 NPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQ 153
P++ WLKNG+EF+ +HRIGG K+R+ WS++M+SVVPSD+GNYTC+VEN++GSI TY
Sbjct: 183 TPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYT 242
Query: 154 LDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDN 213
LDV+ERSPHRPILQAGLPAN+T LGS+VEF CKVYSD QPHIQWLKH+EVNGSK+GPD
Sbjct: 243 LDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDG 302
Query: 214 LPYVQILKVIMAPVFVGQSTGKETTV 239
PYV +LK A +T KE V
Sbjct: 303 TPYVTVLKTAGA-----NTTDKELEV 323
Score = 32.0 bits (71), Expect = 0.68
Identities = 23/87 (26%), Positives = 36/87 (41%), Gaps = 12/87 (13%)
Query: 83 VKFKCPSSGTPNPTLRWLK----NGKEFKPDH-------RIGGYKVRYATWSII-MDSVV 130
V+F C P ++WLK NG + PD + G ++ + +V
Sbjct: 271 VEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVT 330
Query: 131 PSDKGNYTCIVENEYGSINHTYQLDVV 157
D G YTC+ N G +H+ L V+
Sbjct: 331 FEDAGEYTCLAGNSIGFSHHSAWLVVL 357
>gi|254028242 fibroblast growth factor receptor 3 isoform 3
precursor [Homo sapiens]
Length = 808
Score = 277 bits (708), Expect = 9e-75
Identities = 124/188 (65%), Positives = 155/188 (82%), Gaps = 6/188 (3%)
Query: 34 PSSEDDDDDDDSSSEEKETDNTKPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTP 93
PSS DD+D +D E ++T + APYWT PE+M+KKL AVPAA TV+F+CP++G P
Sbjct: 129 PSSGDDEDGED------EAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNP 182
Query: 94 NPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQ 153
P++ WLKNG+EF+ +HRIGG K+R+ WS++M+SVVPSD+GNYTC+VEN++GSI TY
Sbjct: 183 TPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYT 242
Query: 154 LDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDN 213
LDV+ERSPHRPILQAGLPAN+T LGS+VEF CKVYSD QPHIQWLKH+EVNGSK+GPD
Sbjct: 243 LDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDG 302
Query: 214 LPYVQILK 221
PYV +LK
Sbjct: 303 TPYVTVLK 310
>gi|47524177 fibroblast growth factor receptor 4 isoform 2 precursor
[Homo sapiens]
Length = 762
Score = 259 bits (661), Expect = 3e-69
Identities = 124/210 (59%), Positives = 155/210 (73%), Gaps = 9/210 (4%)
Query: 18 LCTARPSP------TLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNPVAPYWTSPEKME 71
LC AR S TL D+L SS +DD+D S + ++ P APYWT P++ME
Sbjct: 100 LCLARGSMIVLQNLTLITGDSLTSS--NDDEDPKSHRDPSNRHSYPQQ-APYWTHPQRME 156
Query: 72 KKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVP 131
KKLHAVPA TVKF+CP++G P PT+RWLK+G+ F ++RIGG ++R+ WS++M+SVVP
Sbjct: 157 KKLHAVPAGNTVKFRCPAAGNPTPTIRWLKDGQAFHGENRIGGIRLRHQHWSLVMESVVP 216
Query: 132 SDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSD 191
SD+G YTC+VEN GSI + Y LDV+ERSPHRPILQAGLPAN T +GS+VE +CKVYSD
Sbjct: 217 SDRGTYTCLVENAVGSIRYNYLLDVLERSPHRPILQAGLPANTTAVVGSDVELLCKVYSD 276
Query: 192 PQPHIQWLKHIEVNGSKIGPDNLPYVQILK 221
QPHIQWLKHI +NGS G D PYVQ+LK
Sbjct: 277 AQPHIQWLKHIVINGSSFGADGFPYVQVLK 306
>gi|47524175 fibroblast growth factor receptor 4 isoform 1 precursor
[Homo sapiens]
Length = 802
Score = 259 bits (661), Expect = 3e-69
Identities = 124/210 (59%), Positives = 155/210 (73%), Gaps = 9/210 (4%)
Query: 18 LCTARPSP------TLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNPVAPYWTSPEKME 71
LC AR S TL D+L SS +DD+D S + ++ P APYWT P++ME
Sbjct: 100 LCLARGSMIVLQNLTLITGDSLTSS--NDDEDPKSHRDPSNRHSYPQQ-APYWTHPQRME 156
Query: 72 KKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVP 131
KKLHAVPA TVKF+CP++G P PT+RWLK+G+ F ++RIGG ++R+ WS++M+SVVP
Sbjct: 157 KKLHAVPAGNTVKFRCPAAGNPTPTIRWLKDGQAFHGENRIGGIRLRHQHWSLVMESVVP 216
Query: 132 SDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSD 191
SD+G YTC+VEN GSI + Y LDV+ERSPHRPILQAGLPAN T +GS+VE +CKVYSD
Sbjct: 217 SDRGTYTCLVENAVGSIRYNYLLDVLERSPHRPILQAGLPANTTAVVGSDVELLCKVYSD 276
Query: 192 PQPHIQWLKHIEVNGSKIGPDNLPYVQILK 221
QPHIQWLKHI +NGS G D PYVQ+LK
Sbjct: 277 AQPHIQWLKHIVINGSSFGADGFPYVQVLK 306
>gi|47524173 fibroblast growth factor receptor 4 isoform 1 precursor
[Homo sapiens]
Length = 802
Score = 259 bits (661), Expect = 3e-69
Identities = 124/210 (59%), Positives = 155/210 (73%), Gaps = 9/210 (4%)
Query: 18 LCTARPSP------TLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNPVAPYWTSPEKME 71
LC AR S TL D+L SS +DD+D S + ++ P APYWT P++ME
Sbjct: 100 LCLARGSMIVLQNLTLITGDSLTSS--NDDEDPKSHRDPSNRHSYPQQ-APYWTHPQRME 156
Query: 72 KKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVP 131
KKLHAVPA TVKF+CP++G P PT+RWLK+G+ F ++RIGG ++R+ WS++M+SVVP
Sbjct: 157 KKLHAVPAGNTVKFRCPAAGNPTPTIRWLKDGQAFHGENRIGGIRLRHQHWSLVMESVVP 216
Query: 132 SDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSD 191
SD+G YTC+VEN GSI + Y LDV+ERSPHRPILQAGLPAN T +GS+VE +CKVYSD
Sbjct: 217 SDRGTYTCLVENAVGSIRYNYLLDVLERSPHRPILQAGLPANTTAVVGSDVELLCKVYSD 276
Query: 192 PQPHIQWLKHIEVNGSKIGPDNLPYVQILK 221
QPHIQWLKHI +NGS G D PYVQ+LK
Sbjct: 277 AQPHIQWLKHIVINGSSFGADGFPYVQVLK 306
>gi|222144233 fibroblast growth factor receptor 2 isoform 4
precursor [Homo sapiens]
Length = 709
Score = 191 bits (484), Expect = 9e-49
Identities = 88/127 (69%), Positives = 101/127 (79%), Gaps = 3/127 (2%)
Query: 31 DALPSSEDDDDDDDSSSEEKETDNTKPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSS 90
DA+ S +D+DD D + E N K APYWT+ EKMEK+LHAVPAA TVKF+CP+
Sbjct: 126 DAISSGDDEDDTDGAEDFVSENSNNKR---APYWTNTEKMEKRLHAVPAANTVKFRCPAG 182
Query: 91 GTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINH 150
G P PT+RWLKNGKEFK +HRIGGYKVR WS+IM+SVVPSDKGNYTC+VENEYGSINH
Sbjct: 183 GNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINH 242
Query: 151 TYQLDVV 157
TY LDVV
Sbjct: 243 TYHLDVV 249
Score = 35.4 bits (80), Expect = 0.062
Identities = 45/229 (19%), Positives = 76/229 (33%), Gaps = 63/229 (27%)
Query: 1 MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNPV 60
M SW + V+ ATL ARPS +L E L E P
Sbjct: 1 MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEE---------------------PP 39
Query: 61 APYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHR---IGGYKV 117
Y S + +++ ++++ +C + W K+G P++R IG Y
Sbjct: 40 TKYQIS----QPEVYVAAPGESLEVRCLLKDAA--VISWTKDGVHLGPNNRTVLIGEY-- 91
Query: 118 RYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVE------------------- 158
+ + P D G Y C S + ++V +
Sbjct: 92 ------LQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVS 145
Query: 159 ------RSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKH 201
R+P+ + V + V+F C +P P ++WLK+
Sbjct: 146 ENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKN 194
>gi|51988914 fibroblast growth factor receptor-like 1 precursor
[Homo sapiens]
Length = 504
Score = 120 bits (302), Expect = 1e-27
Identities = 62/173 (35%), Positives = 90/173 (52%), Gaps = 6/173 (3%)
Query: 31 DALPSSEDDDDDDDSSSEEKETDNTKPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSS 90
D P E D S +E D P +T P KM +++ A P +V+ KC +S
Sbjct: 119 DISPGKESLGPDSSSGGQE---DPASQQWARPRFTQPSKMRRRVIARPVGSSVRLKCVAS 175
Query: 91 GTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINH 150
G P P + W+K+ + R + R W++ + ++ P D G YTC V N G+IN
Sbjct: 176 GHPRPDITWMKDDQALT---RPEAAEPRKKKWTLSLKNLRPEDSGKYTCRVSNRAGAINA 232
Query: 151 TYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIE 203
TY++DV++R+ +P+L P N TV G F CKV SD +P IQWLK +E
Sbjct: 233 TYKVDVIQRTRSKPVLTGTHPVNTTVDFGGTTSFQCKVRSDVKPVIQWLKRVE 285
Score = 50.4 bits (119), Expect = 2e-06
Identities = 43/171 (25%), Positives = 64/171 (37%), Gaps = 33/171 (19%)
Query: 59 PVAPYWTSPEKMEKKL---HAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGY 115
P A P KM K+ +TV+ +CP G P P W K+G+ G
Sbjct: 20 PPAAAARGPPKMADKVVPRQVARLGRTVRLQCPVEGDPPPLTMWTKDGRTI----HSGWS 75
Query: 116 KVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVER-SPHRPIL-------- 166
+ R + + V D G Y C N +GS++ Y L V++ SP + L
Sbjct: 76 RFRVLPQGLKVKQVEREDAGVYVCKATNGFGSLSVNYTLVVLDDISPGKESLGPDSSSGG 135
Query: 167 ---------------QAGLPANKTVA--LGSNVEFMCKVYSDPQPHIQWLK 200
Q + +A +GS+V C P+P I W+K
Sbjct: 136 QEDPASQQWARPRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRPDITWMK 186
>gi|51988910 fibroblast growth factor receptor-like 1 precursor
[Homo sapiens]
Length = 504
Score = 120 bits (302), Expect = 1e-27
Identities = 62/173 (35%), Positives = 90/173 (52%), Gaps = 6/173 (3%)
Query: 31 DALPSSEDDDDDDDSSSEEKETDNTKPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSS 90
D P E D S +E D P +T P KM +++ A P +V+ KC +S
Sbjct: 119 DISPGKESLGPDSSSGGQE---DPASQQWARPRFTQPSKMRRRVIARPVGSSVRLKCVAS 175
Query: 91 GTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINH 150
G P P + W+K+ + R + R W++ + ++ P D G YTC V N G+IN
Sbjct: 176 GHPRPDITWMKDDQALT---RPEAAEPRKKKWTLSLKNLRPEDSGKYTCRVSNRAGAINA 232
Query: 151 TYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIE 203
TY++DV++R+ +P+L P N TV G F CKV SD +P IQWLK +E
Sbjct: 233 TYKVDVIQRTRSKPVLTGTHPVNTTVDFGGTTSFQCKVRSDVKPVIQWLKRVE 285
Score = 50.4 bits (119), Expect = 2e-06
Identities = 43/171 (25%), Positives = 64/171 (37%), Gaps = 33/171 (19%)
Query: 59 PVAPYWTSPEKMEKKL---HAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGY 115
P A P KM K+ +TV+ +CP G P P W K+G+ G
Sbjct: 20 PPAAAARGPPKMADKVVPRQVARLGRTVRLQCPVEGDPPPLTMWTKDGRTI----HSGWS 75
Query: 116 KVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVER-SPHRPIL-------- 166
+ R + + V D G Y C N +GS++ Y L V++ SP + L
Sbjct: 76 RFRVLPQGLKVKQVEREDAGVYVCKATNGFGSLSVNYTLVVLDDISPGKESLGPDSSSGG 135
Query: 167 ---------------QAGLPANKTVA--LGSNVEFMCKVYSDPQPHIQWLK 200
Q + +A +GS+V C P+P I W+K
Sbjct: 136 QEDPASQQWARPRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRPDITWMK 186
>gi|51988912 fibroblast growth factor receptor-like 1 precursor
[Homo sapiens]
Length = 504
Score = 120 bits (302), Expect = 1e-27
Identities = 62/173 (35%), Positives = 90/173 (52%), Gaps = 6/173 (3%)
Query: 31 DALPSSEDDDDDDDSSSEEKETDNTKPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSS 90
D P E D S +E D P +T P KM +++ A P +V+ KC +S
Sbjct: 119 DISPGKESLGPDSSSGGQE---DPASQQWARPRFTQPSKMRRRVIARPVGSSVRLKCVAS 175
Query: 91 GTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINH 150
G P P + W+K+ + R + R W++ + ++ P D G YTC V N G+IN
Sbjct: 176 GHPRPDITWMKDDQALT---RPEAAEPRKKKWTLSLKNLRPEDSGKYTCRVSNRAGAINA 232
Query: 151 TYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIE 203
TY++DV++R+ +P+L P N TV G F CKV SD +P IQWLK +E
Sbjct: 233 TYKVDVIQRTRSKPVLTGTHPVNTTVDFGGTTSFQCKVRSDVKPVIQWLKRVE 285
Score = 50.4 bits (119), Expect = 2e-06
Identities = 43/171 (25%), Positives = 64/171 (37%), Gaps = 33/171 (19%)
Query: 59 PVAPYWTSPEKMEKKL---HAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGY 115
P A P KM K+ +TV+ +CP G P P W K+G+ G
Sbjct: 20 PPAAAARGPPKMADKVVPRQVARLGRTVRLQCPVEGDPPPLTMWTKDGRTI----HSGWS 75
Query: 116 KVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVER-SPHRPIL-------- 166
+ R + + V D G Y C N +GS++ Y L V++ SP + L
Sbjct: 76 RFRVLPQGLKVKQVEREDAGVYVCKATNGFGSLSVNYTLVVLDDISPGKESLGPDSSSGG 135
Query: 167 ---------------QAGLPANKTVA--LGSNVEFMCKVYSDPQPHIQWLK 200
Q + +A +GS+V C P+P I W+K
Sbjct: 136 QEDPASQQWARPRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRPDITWMK 186
>gi|142976733 surface glycoprotein, Ig superfamily member [Homo
sapiens]
Length = 1264
Score = 73.9 bits (180), Expect = 2e-13
Identities = 42/129 (32%), Positives = 68/129 (52%), Gaps = 11/129 (8%)
Query: 76 AVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKG 135
AV + V +C SG P P + WLK+G++ P G R + DSV P+D G
Sbjct: 232 AVLSRSPVTLECVVSGVPAPQVYWLKDGQDIAP-----GSNWRRLYSHLATDSVDPADSG 286
Query: 136 NYTCIVENEYGSINH-TYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQP 194
NY+C+ N+ G + + TY ++V+E + LQ ++ V+LG+ V F C V+ +P P
Sbjct: 287 NYSCMAGNKSGDVKYVTYMVNVLEHASISKGLQ-----DQIVSLGATVHFTCDVHGNPAP 341
Query: 195 HIQWLKHIE 203
+ W + +
Sbjct: 342 NCTWFHNAQ 350
Score = 51.6 bits (122), Expect = 8e-07
Identities = 33/124 (26%), Positives = 49/124 (39%), Gaps = 10/124 (8%)
Query: 77 VPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPD--HRIGGYKVRYATWSIIMDSVVPSDK 134
V TV F C G P P W N + P H G ++ + V D
Sbjct: 323 VSLGATVHFTCDVHGNPAPNCTWFHNAQPIHPSARHLTAGNGLK-------ISGVTVEDV 375
Query: 135 GNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQP 194
G Y C+ +N G ++ T +L++ +P++ P + VA G V C P P
Sbjct: 376 GMYQCVADNGIGFMHSTGRLEIENDGGFKPVIITA-PVSAKVADGDFVTLSCNASGLPVP 434
Query: 195 HIQW 198
I+W
Sbjct: 435 VIRW 438
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 73.2 bits (178), Expect = 3e-13
Identities = 52/167 (31%), Positives = 77/167 (46%), Gaps = 12/167 (7%)
Query: 79 AAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYT 138
A + ++F CP+ GTP PT++WL NG+E R G + +++ SV P D G Y
Sbjct: 1280 ANQRIEFPCPAKGTPKPTIKWLHNGREL--TGREPGISILEDGTLLVIASVTPYDNGEYI 1337
Query: 139 CIVENEYGSINHTYQLDVVERSPHRP--ILQAGLPANKTVALGSNVEFMCKVYSDPQPHI 196
C+ NE G+ Y L V H P I N +V L C+V P P I
Sbjct: 1338 CVAVNEAGTTERKYNLKV-----HVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPII 1392
Query: 197 QWLK-HIEVNGSKIGPDNLPYVQILKVIMA-PVFVGQSTGKETTVSG 241
W K +++V S + +ILK+ A P G+ + K ++G
Sbjct: 1393 MWYKDNVQVTESST-IQTVNNGKILKLFRATPEDAGRYSCKAINIAG 1438
Score = 70.5 bits (171), Expect = 2e-12
Identities = 46/141 (32%), Positives = 64/141 (45%), Gaps = 16/141 (11%)
Query: 66 SPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRI------GGYKVRY 119
S E E+++ + V C ++G P PT+ WLKN K + + GG K++
Sbjct: 3152 SIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQI 3211
Query: 120 ATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALG 179
A SD GNYTCI N G Y L + + A +P++ +V LG
Sbjct: 3212 ARSQ-------HSDSGNYTCIASNMEGKAQKYYFLSI---QVPPSVAGAEIPSDVSVLLG 3261
Query: 180 SNVEFMCKVYSDPQPHIQWLK 200
NVE +C P P IQWLK
Sbjct: 3262 ENVELVCNANGIPTPLIQWLK 3282
Score = 61.6 bits (148), Expect = 8e-10
Identities = 37/122 (30%), Positives = 57/122 (46%), Gaps = 9/122 (7%)
Query: 81 KTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCI 140
K V +C ++G PNP++ WLK+ + G K++ + + + + D G YTC+
Sbjct: 1842 KPVALQCIANGIPNPSITWLKDDQPVNTAQ--GNLKIQSSGRVLQIAKTLLEDAGRYTCV 1899
Query: 141 VENEYGSINHTYQLDVVERSPHRP--ILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQW 198
N G QL V H P + AG N+TV + + V+ CK +P P I W
Sbjct: 1900 ATNAAGETQQHIQLHV-----HEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITW 1954
Query: 199 LK 200
K
Sbjct: 1955 YK 1956
Score = 58.5 bits (140), Expect = 7e-09
Identities = 34/121 (28%), Positives = 53/121 (43%), Gaps = 9/121 (7%)
Query: 78 PAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNY 137
P C G P PT++W + G + + HRI + S+ + V D G+Y
Sbjct: 4362 PLGGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIR----QLGNGSLAIYGTVNEDAGDY 4417
Query: 138 TCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQ 197
TC+ NE G + + L + +SP PI+ P + G + C+ +PQP I
Sbjct: 4418 TCVATNEAGVVERSMSLTL--QSP--PIITLE-PVETVINAGGKIILNCQATGEPQPTIT 4472
Query: 198 W 198
W
Sbjct: 4473 W 4473
Score = 56.6 bits (135), Expect = 3e-08
Identities = 42/150 (28%), Positives = 64/150 (42%), Gaps = 21/150 (14%)
Query: 56 KPNPVAPYWTSPEKMEKKLHAVPAAKTVK-FKCPSSGTPNPTLRWLKNGKEFKP------ 108
K N Y +P+ M + + A + +C +SG P P ++W K E +P
Sbjct: 691 KQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLII 750
Query: 109 DHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQA 168
D +G K++ D G+YTC+ NE G LDV P +
Sbjct: 751 DPLLGLLKIQ---------ETQDLDAGDYTCVAINEAGRATGKITLDVGS-----PPVFI 796
Query: 169 GLPANKTVALGSNVEFMCKVYSDPQPHIQW 198
PA+ ++ +GSNV C V P+P I+W
Sbjct: 797 QEPADVSMEIGSNVTLPCYVQGYPEPTIKW 826
Score = 55.5 bits (132), Expect = 6e-08
Identities = 40/139 (28%), Positives = 57/139 (41%), Gaps = 13/139 (9%)
Query: 67 PEKMEK--KLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSI 124
P K+++ K V + V C + GTP P + W K G D G + V ++
Sbjct: 1170 PPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVD---GEHHVSNPDGTL 1226
Query: 125 IMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTV----ALGS 180
+D PSD G YTC+ N G+ L V E P ++ P T
Sbjct: 1227 SIDQATPSDAGIYTCVATNIAGTDETEITLHVQE----PPTVEDLEPPYNTTFQERVANQ 1282
Query: 181 NVEFMCKVYSDPQPHIQWL 199
+EF C P+P I+WL
Sbjct: 1283 RIEFPCPAKGTPKPTIKWL 1301
Score = 55.5 bits (132), Expect = 6e-08
Identities = 34/125 (27%), Positives = 59/125 (47%), Gaps = 8/125 (6%)
Query: 77 VPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGN 136
V A ++ +C ++G P+P L WLK+G K + I ++ + + S D+G
Sbjct: 1653 VVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNI---RIEAGGKKLEIMSAQEIDRGQ 1709
Query: 137 YTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSN-VEFMCKVYSDPQPH 195
Y C+ + G Y++DV+ P ++ G + + + +N +E C V P P
Sbjct: 1710 YICVATSVAGEKEIKYEVDVLV----PPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPT 1765
Query: 196 IQWLK 200
I WLK
Sbjct: 1766 IMWLK 1770
Score = 55.5 bits (132), Expect = 6e-08
Identities = 48/167 (28%), Positives = 69/167 (41%), Gaps = 8/167 (4%)
Query: 76 AVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKG 135
AV V+ +C + G P P+L WLK+G G +V + + S SD G
Sbjct: 2022 AVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFS--NGLQVLSGGRILALTSAQISDTG 2079
Query: 136 NYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPH 195
YTC+ N G L V + P G N +V + VE +C+ + P P
Sbjct: 2080 RYTCVAVNAAGEKQRDIDLRV-----YVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPT 2134
Query: 196 IQWLKHIEVNGSKIGPDNLPYVQILKVIMAPV-FVGQSTGKETTVSG 241
+ WLK K G +LK+ A V G+ T + T V+G
Sbjct: 2135 LTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAG 2181
Score = 55.5 bits (132), Expect = 6e-08
Identities = 38/122 (31%), Positives = 56/122 (45%), Gaps = 9/122 (7%)
Query: 87 CPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYG 146
C +SG P P++ W KNG P R GY++ ++ +I + + + G YTC+ N G
Sbjct: 3918 CTASGVPFPSIHWTKNGIRLLP--RGDGYRI-LSSGAIEILATQLNHAGRYTCVARNAAG 3974
Query: 147 SINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKH-IEVN 205
S + L V H P + P+ V L + + C+ P P I W K I VN
Sbjct: 3975 SAHRHVTLHV-----HEPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVN 4029
Query: 206 GS 207
S
Sbjct: 4030 TS 4031
Score = 54.3 bits (129), Expect = 1e-07
Identities = 34/124 (27%), Positives = 54/124 (43%), Gaps = 5/124 (4%)
Query: 77 VPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGN 136
V K++ +C G P PT+ W+K+G P + G ++ + + ++ SD G
Sbjct: 2304 VTRGKSISLECEVQGIPPPTVTWMKDG---HPLIKAKGVEILDEGHILQLKNIHVSDTGR 2360
Query: 137 YTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHI 196
Y C+ N G + Y L V +P I P N +V ++V C+ P P I
Sbjct: 2361 YVCVAVNVAGMTDKKYDLSV--HAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSI 2418
Query: 197 QWLK 200
W K
Sbjct: 2419 TWFK 2422
Score = 54.3 bits (129), Expect = 1e-07
Identities = 34/118 (28%), Positives = 50/118 (42%), Gaps = 13/118 (11%)
Query: 83 VKFKCPSSGTPNPTLRWLKNGKEFKPDH--RIGGYKVRYATWSIIMDSVVPSDKGNYTCI 140
++ C ++G P P L W N P H + G+ ++++ V D G Y C
Sbjct: 4277 LRLSCKATGIPLPKLTWTFNNNII-PAHFDSVNGHS------ELVIERVSKEDSGTYVCT 4329
Query: 141 VENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQW 198
EN G + + V E P+ + P+N LG N C+V DP P IQW
Sbjct: 4330 AENSVGFVKAIGFVYVKEP----PVFKGDYPSNWIEPLGGNAILNCEVKGDPTPTIQW 4383
Score = 53.5 bits (127), Expect = 2e-07
Identities = 35/127 (27%), Positives = 54/127 (42%), Gaps = 9/127 (7%)
Query: 77 VPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPD---HRIGGYKVRYATWSIIMDSVVPSD 133
V ++V C +G P P + W K+G+ + D H I G + T +V
Sbjct: 2491 VKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQIT------NVQVPH 2544
Query: 134 KGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQ 193
G YTC+ + G + ++ L+V + G P + TV L S +C+ YS P
Sbjct: 2545 TGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPP 2604
Query: 194 PHIQWLK 200
I W K
Sbjct: 2605 ATITWFK 2611
Score = 53.1 bits (126), Expect = 3e-07
Identities = 33/120 (27%), Positives = 55/120 (45%), Gaps = 9/120 (7%)
Query: 83 VKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVE 142
+K +C + G P P + W K+G+ + + + I + V SD YTC V
Sbjct: 1565 IKLECETRGLPMPAITWYKDGQPIMSSSQ--ALYIDKGQYLHIPRAQV-SDSATYTCHVA 1621
Query: 143 NEYGSINHTYQLDVVERSPHRPILQAGL--PANKTVALGSNVEFMCKVYSDPQPHIQWLK 200
N G+ ++ +DV P+++ L P NK V + ++ CK +P P + WLK
Sbjct: 1622 NVAGTAEKSFHVDVYVP----PMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLK 1677
Score = 51.2 bits (121), Expect = 1e-06
Identities = 45/186 (24%), Positives = 68/186 (36%), Gaps = 11/186 (5%)
Query: 22 RPSPTLPEQDALPSSEDDDDDDDSSSEEKETD---NTKPNPVAPYWTSPE---KMEKKLH 75
+P ++ E ++ ED D + T+ T+ N W P E
Sbjct: 2147 KPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQL 2206
Query: 76 AVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKG 135
V + C SSG P P L W K G D +G ++ + + SD
Sbjct: 2207 TVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDS-MGRVRILSGGRQLQISIAEKSDAA 2265
Query: 136 NYTCIVENEYGSINHTYQLDVVERSPHRPILQAGL-PANKTVALGSNVEFMCKVYSDPQP 194
Y+C+ N G+ Y L V R I +G P V G ++ C+V P P
Sbjct: 2266 LYSCVASNVAGTAKKEYNLQVYIRPT---ITNSGSHPTEIIVTRGKSISLECEVQGIPPP 2322
Query: 195 HIQWLK 200
+ W+K
Sbjct: 2323 TVTWMK 2328
Score = 51.2 bits (121), Expect = 1e-06
Identities = 41/151 (27%), Positives = 66/151 (43%), Gaps = 9/151 (5%)
Query: 81 KTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCI 140
K+ +C SSG+P P W K+G+ D +K + + + +D G Y C+
Sbjct: 2888 KSALIECLSSGSPAPRNSWQKDGQPLLEDDH---HKFLSNGRILQILNTQITDIGRYVCV 2944
Query: 141 VENEYGSINHTYQLDVVERSPHRPILQAGLPA-NKTVALGSNVEFMCKVYSDPQPHIQWL 199
EN GS + L+V H P G + N TV + + + C+V P P + WL
Sbjct: 2945 AENTAGSAKKYFNLNV-----HVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWL 2999
Query: 200 KHIEVNGSKIGPDNLPYVQILKVIMAPVFVG 230
K+ + +P + L++I A V G
Sbjct: 3000 KNEQPIKLNTNTLIVPGGRTLQIIRAKVSDG 3030
Score = 50.8 bits (120), Expect = 1e-06
Identities = 33/126 (26%), Positives = 53/126 (42%), Gaps = 3/126 (2%)
Query: 76 AVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKG 135
+V + V+ C ++G P P ++WLK+GK +V ++ + + SD G
Sbjct: 3257 SVLLGENVELVCNANGIPTPLIQWLKDGKPI-ASGETERIRVSANGSTLNIYGALTSDTG 3315
Query: 136 NYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPH 195
YTC+ N G + + L+V R V N+E C+ P P
Sbjct: 3316 KYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIE--CRATGTPPPQ 3373
Query: 196 IQWLKH 201
I WLK+
Sbjct: 3374 INWLKN 3379
Score = 50.4 bits (119), Expect = 2e-06
Identities = 32/118 (27%), Positives = 51/118 (43%), Gaps = 9/118 (7%)
Query: 83 VKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVE 142
V C ++G P P + W N HR Y++ + ++ + + P D G Y C+
Sbjct: 629 VSIMCSATGYPKPKIAWTVNDMFIVGSHR---YRMT-SDGTLFIKNAAPKDAGIYGCLAS 684
Query: 143 NEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLK 200
N G+ L +E +P ++Q+ L VALG CK P P ++W K
Sbjct: 685 NSAGTDKQNSTLRYIE-APKLMVVQSEL----LVALGDITVMECKTSGIPPPQVKWFK 737
Score = 50.1 bits (118), Expect = 2e-06
Identities = 37/132 (28%), Positives = 55/132 (41%), Gaps = 12/132 (9%)
Query: 82 TVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIV 141
++ +C ++GTP P + WLKNG I ++ A I + SD YTC+
Sbjct: 3359 SINIECRATGTPPPQINWLKNGLPLPLSSHI---RLLAAGQVIRIVRAQVSDVAVYTCVA 3415
Query: 142 ENEYGSINHTYQLDVVERSPHRPILQAGLPANK-TVALGSNVEFMCKVYSDPQPHIQWLK 200
N G N Y L V P + + + TV GS+ C P P + WL+
Sbjct: 3416 SNRAGVDNKHYNLQVFA----PPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLR 3471
Query: 201 HIEVNGSKIGPD 212
+G +G D
Sbjct: 3472 ----DGQPLGLD 3479
Score = 50.1 bits (118), Expect = 2e-06
Identities = 46/173 (26%), Positives = 69/173 (39%), Gaps = 29/173 (16%)
Query: 81 KTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSII------MDSVVPSDK 134
K+ +C + G P P + W K+G +H A +SI+ + S +D
Sbjct: 3728 KSTVLECIAEGVPTPRITWRKDGAVLAGNH---------ARYSILENGFLHIQSAHVTDT 3778
Query: 135 GNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQP 194
G Y C+ N G+ L V H P A P N TV + C+ P+P
Sbjct: 3779 GRYLCMATNAAGTDRRRIDLQV-----HVPPSIAPGPTNMTVIVNVQTTLACEATGIPKP 3833
Query: 195 HIQWLKHIEVNGSKIGPD-NLPYVQILK----VIMAPVFVGQSTGKETTVSGA 242
I W K NG + D N ++L VI++P +T + T +GA
Sbjct: 3834 SINWRK----NGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGA 3882
Score = 49.7 bits (117), Expect = 3e-06
Identities = 32/116 (27%), Positives = 54/116 (46%), Gaps = 10/116 (8%)
Query: 87 CPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMD--SVVPSDKGNYTCIVENE 144
C + GTP P++ WL++G+ D + +T +++ D G YTCI NE
Sbjct: 3457 CITDGTPAPSMAWLRDGQPLGLDAHL-----TVSTHGMVLQLLKAETEDSGKYTCIASNE 3511
Query: 145 YGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLK 200
G ++ + L V+E PH I + +V + + +E C P P + W+K
Sbjct: 3512 AGEVSKHFILKVLE-PPH--INGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMK 3564
Score = 49.3 bits (116), Expect = 4e-06
Identities = 49/191 (25%), Positives = 78/191 (40%), Gaps = 37/191 (19%)
Query: 66 SPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRI----GGYKVRYAT 121
SPE + +V +V C +SG P P++ W K+G + + GG +R
Sbjct: 2392 SPENI-----SVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLR--- 2443
Query: 122 WSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSN 181
+M + + D G YTC+V N G + L V+ PH I+ + V +
Sbjct: 2444 ---LMQTTM-EDAGQYTCVVRNAAGEERKIFGLSVLV-PPH--IVGENTLEDVKVKEKQS 2496
Query: 182 VEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKVIMAPVFVGQSTGKETTVSG 241
V C+V +P P I W K +G + D ++ S G+ ++
Sbjct: 2497 VTLTCEVTGNPVPEITWHK----DGQPLQEDEAHHI-------------ISGGRFLQITN 2539
Query: 242 AQVP-VGRLSC 251
QVP GR +C
Sbjct: 2540 VQVPHTGRYTC 2550
Score = 49.3 bits (116), Expect = 4e-06
Identities = 41/144 (28%), Positives = 63/144 (43%), Gaps = 24/144 (16%)
Query: 83 VKFKCPSSGTPNPTLRWLKNGKEFKPDHRI----GGYKVRYATWSIIMDSVVPSDKGNYT 138
++ C +SG P P + W+K+G+ ++ GG +R +T + D G YT
Sbjct: 3546 LELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQV-------EDTGRYT 3598
Query: 139 CIVENEYGSINHTYQLDVVERSPHRPILQAGL--PANKTVALGSNVEFMCKVYSDPQPHI 196
C+ + G + Y + V H P AG P + TV V CK + P P I
Sbjct: 3599 CLASSPAGDDDKEYLVRV-----HVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVI 3653
Query: 197 QWLKHIEVNGSKIGPDNLPYVQIL 220
WL+ NG ++ P V+IL
Sbjct: 3654 TWLR----NGERL--QATPRVRIL 3671
Score = 49.3 bits (116), Expect = 4e-06
Identities = 31/112 (27%), Positives = 46/112 (41%), Gaps = 8/112 (7%)
Query: 87 CPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYG 146
C + G P P + W K+ + +G Y +I+++VV D G YTC+ N G
Sbjct: 4190 CVADGIPTPAINWKKDNVLLA--NLLGKYTAE-PYGELILENVVLEDSGFYTCVANNAAG 4246
Query: 147 SINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQW 198
HT L V H LP + ++ G + CK P P + W
Sbjct: 4247 EDTHTVSLTV-----HVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTW 4293
Score = 48.5 bits (114), Expect = 7e-06
Identities = 32/118 (27%), Positives = 54/118 (45%), Gaps = 7/118 (5%)
Query: 83 VKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVE 142
++ C +G+P PT+ WLK+G+ D R G+K+ +++ S+ G Y C+
Sbjct: 1752 LELDCHVTGSPPPTIMWLKDGQLI--DER-DGFKILLNGRKLVIAQAQVSNTGLYRCMAA 1808
Query: 143 NEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLK 200
N G +H + +V P P +++ + + V V C P P I WLK
Sbjct: 1809 NTAG--DHKKEFEVTVHVP--PTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLK 1862
Score = 47.4 bits (111), Expect = 2e-05
Identities = 39/145 (26%), Positives = 57/145 (39%), Gaps = 12/145 (8%)
Query: 56 KPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGY 115
K N P SP E + + K + C + G P P + W K+G+ R
Sbjct: 4072 KLNVQVPPVISPHLKE---YVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIR---- 4124
Query: 116 KVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKT 175
+ ++ S+ + V P D G+YTC+ N GS + + +L V H P + T
Sbjct: 4125 QRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV-----HVPPRIRSTEGHYT 4179
Query: 176 VALGSNVEFMCKVYSDPQPHIQWLK 200
V S C P P I W K
Sbjct: 4180 VNENSQAILPCVADGIPTPAINWKK 4204
Score = 46.6 bits (109), Expect = 3e-05
Identities = 39/150 (26%), Positives = 66/150 (44%), Gaps = 10/150 (6%)
Query: 71 EKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVV 130
E++ +V ++ V+ C S P PTL WLK+G P + G + + ++
Sbjct: 2109 EEQNVSVLISQAVELLCQSDAIPPPTLTWLKDG---HPLLKKPGLSISENRSVLKIEDAQ 2165
Query: 131 PSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYS 190
D G YTC N G Y +++ P+ I + TV G+ + +C+
Sbjct: 2166 VQDTGRYTCEATNVAGKTEKNYNVNIWV-PPN--IGGSDELTQLTVIEGNLISLLCESSG 2222
Query: 191 DPQPHIQWLKHIEVNGSKIGPDNLPYVQIL 220
P P++ W K GS + D++ V+IL
Sbjct: 2223 IPPPNLIWKK----KGSPVLTDSMGRVRIL 2248
Score = 46.6 bits (109), Expect = 3e-05
Identities = 34/125 (27%), Positives = 49/125 (39%), Gaps = 10/125 (8%)
Query: 87 CPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYG 146
C ++G P P++ W KNG D Y++ ++ S+++ S D Y C V N G
Sbjct: 3825 CEATGIPKPSINWRKNGHLLNVDQNQNSYRL-LSSGSLVIISPSVDDTATYECTVTNGAG 3883
Query: 147 SINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNG 206
T L V P A P + V + C P P I W K NG
Sbjct: 3884 DDKRTVDLTV-----QVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTK----NG 3934
Query: 207 SKIGP 211
++ P
Sbjct: 3935 IRLLP 3939
Score = 46.2 bits (108), Expect = 3e-05
Identities = 29/120 (24%), Positives = 48/120 (40%), Gaps = 8/120 (6%)
Query: 81 KTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCI 140
+ V +C S P P + WL+NG+ + R+ ++ + +++ D NYTC+
Sbjct: 3637 RQVTLECKSDAVPPPVITWLRNGERLQATPRV---RILSGGRYLQINNADLGDTANYTCV 3693
Query: 141 VENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLK 200
N G + L V + P G P + + L + C P P I W K
Sbjct: 3694 ASNIAGKTTREFILTV-----NVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRK 3748
Score = 45.4 bits (106), Expect = 6e-05
Identities = 36/153 (23%), Positives = 54/153 (35%), Gaps = 26/153 (16%)
Query: 65 TSPEKMEKKLHAVPAAKT--------------VKFKCPSSGTPNPTLRWLKNG---KEFK 107
T+ K K+H P K C GTP+P + W K+ E
Sbjct: 1346 TTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESS 1405
Query: 108 PDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQ 167
+ K+ + + P D G Y+C N G+ + +DV+ I+
Sbjct: 1406 TIQTVNNGKI------LKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPT---IIG 1456
Query: 168 AGLPANKTVALGSNVEFMCKVYSDPQPHIQWLK 200
P +V L +V C+V P P I W K
Sbjct: 1457 TNFPNEVSVVLNRDVALECQVKGTPFPDIHWFK 1489
Score = 45.1 bits (105), Expect = 8e-05
Identities = 35/128 (27%), Positives = 51/128 (39%), Gaps = 14/128 (10%)
Query: 76 AVPAAKTVKFKCPSSGTPNPTLRWLKNGK---EFKPDHRIGGYKVRYATWSIIMDSVVPS 132
+V A + V C P P + W K + F P H + S+ + S
Sbjct: 1090 SVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTF------LPSGSMKITETRTS 1143
Query: 133 DKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDP 192
D G Y C+ N G++ +L+V P P +Q G P + V +G V+ C P
Sbjct: 1144 DSGMYLCVATNIAGNVTQAVKLNV--HVP--PKIQRG-PKHLKVQVGQRVDIPCNAQGTP 1198
Query: 193 QPHIQWLK 200
P I W K
Sbjct: 1199 LPVITWSK 1206
Score = 44.7 bits (104), Expect = 1e-04
Identities = 38/129 (29%), Positives = 52/129 (40%), Gaps = 14/129 (10%)
Query: 83 VKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRY---ATWSIIMDSVVPSDKGNYTC 139
V C +SG P P++ W K G+ I ++ A S+ + S + G Y C
Sbjct: 998 VTLPCKASGNPKPSVIWSKKGE------LISTSSAKFSAGADGSLYVVSPGGEESGEYVC 1051
Query: 140 IVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVAL----GSNVEFMCKVYSDPQPH 195
N G QL V R P Q GL +K V + G V C+V S P P
Sbjct: 1052 TATNTAGYAKRKVQLTVYVR-PRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPI 1110
Query: 196 IQWLKHIEV 204
I W K ++
Sbjct: 1111 ITWAKETQL 1119
Score = 44.3 bits (103), Expect = 1e-04
Identities = 47/164 (28%), Positives = 64/164 (39%), Gaps = 13/164 (7%)
Query: 83 VKFKCPSSGTPNPTLRWLKNGKEFKPDHRI----GGYKVRYATWSIIMDSVVPSDKGNYT 138
+ C SG P P L WLKN + K + GG T II V SD G YT
Sbjct: 2982 ISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGG-----RTLQIIRAKV--SDGGEYT 3034
Query: 139 CIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQW 198
CI N+ G + L V + L V G++V C+ + P P I W
Sbjct: 3035 CIAINQAGESKKKFSLTVYVPPSIKDHDSESLSV-VNVREGTSVSLECESNAVPPPVITW 3093
Query: 199 LKHIEVNGSKIGPDNLPYVQILKVIMAPVF-VGQSTGKETTVSG 241
K+ + + L Q+L + A V GQ + V+G
Sbjct: 3094 YKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAG 3137
Score = 43.9 bits (102), Expect = 2e-04
Identities = 37/182 (20%), Positives = 77/182 (42%), Gaps = 18/182 (9%)
Query: 66 SPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSII 125
SP++++ K++ T+ +C + P+ +L W K+G+ K D + + ++
Sbjct: 2680 SPKEVKIKVN-----NTLTLECEAYAIPSASLSWYKDGQPLKSDDHV---NIAANGHTLQ 2731
Query: 126 MDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPAN-------KTVAL 178
+ SD G YTC+ N G + +++ + + + G + K V +
Sbjct: 2732 IKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVII 2791
Query: 179 GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKVIMAPVFVGQSTGKETT 238
+ + C+ + P P + W K S LP ++L++ A V + G+ T
Sbjct: 2792 NNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKV---EDAGRYTC 2848
Query: 239 VS 240
V+
Sbjct: 2849 VA 2850
Score = 43.5 bits (101), Expect = 2e-04
Identities = 35/115 (30%), Positives = 51/115 (44%), Gaps = 9/115 (7%)
Query: 90 SGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSIN 149
+G P P RW+KN + I VR + S+ ++ V D G YTC+ N G+ N
Sbjct: 915 AGNPIPERRWIKNSAMLLQNPYI---TVR-SDGSLHIERVQLQDGGEYTCVASNVAGTNN 970
Query: 150 HTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEV 204
T + V P +Q G T+ G V CK +P+P + W K E+
Sbjct: 971 KTTSVVV----HVLPTIQHGQQILSTIE-GIPVTLPCKASGNPKPSVIWSKKGEL 1020
Score = 43.5 bits (101), Expect = 2e-04
Identities = 31/125 (24%), Positives = 49/125 (39%), Gaps = 18/125 (14%)
Query: 83 VKFKCPSSGTPNPTLRWLKNGKEFKPDHRI----GGYKVRYATWSIIMDSVVPSDKGNYT 138
+ C ++ P PTL W K+G ++ GG ++ + D G YT
Sbjct: 2795 ISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKV-------EDAGRYT 2847
Query: 139 CIVENEYGSINHTYQLDVVERSPHRPILQ---AGLPANKTVALGSNVEFMCKVYSDPQPH 195
C+ NE G + Y + V+ PI++ + LP TV + + C P P
Sbjct: 2848 CVAVNEAGEDSLQYDVRVLV----PPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPR 2903
Query: 196 IQWLK 200
W K
Sbjct: 2904 NSWQK 2908
Score = 42.7 bits (99), Expect = 4e-04
Identities = 32/126 (25%), Positives = 50/126 (39%), Gaps = 12/126 (9%)
Query: 77 VPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMD--SVVPSDK 134
V + V+ +C ++G P P + W K+ + G + + I+D S SD
Sbjct: 1932 VLVSNPVQLECKAAGNPVPVITWYKDNRLLS-----GSTSMTFLNRGQIIDIESAQISDA 1986
Query: 135 GNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQP 194
G Y C+ N G+ Y L V H +G V + + V C+ P P
Sbjct: 1987 GIYKCVAINSAGATELFYSLQV-----HVAPSISGSNNMVAVVVNNPVRLECEARGIPAP 2041
Query: 195 HIQWLK 200
+ WLK
Sbjct: 2042 SLTWLK 2047
Score = 41.6 bits (96), Expect = 9e-04
Identities = 27/79 (34%), Positives = 37/79 (46%), Gaps = 5/79 (6%)
Query: 120 ATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALG 179
A S+ + SV +D G Y C+V +E GS + L V E P +P N++ G
Sbjct: 572 ANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQE-----PPKVTVMPKNQSFTGG 626
Query: 180 SNVEFMCKVYSDPQPHIQW 198
S V MC P+P I W
Sbjct: 627 SEVSIMCSATGYPKPKIAW 645
Score = 41.6 bits (96), Expect = 9e-04
Identities = 31/122 (25%), Positives = 53/122 (43%), Gaps = 9/122 (7%)
Query: 81 KTVKFKCPSSGTPNPTLRWLKNGKE-FKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTC 139
+ V +C GTP P + W K+GK F D + ++ + + + +DKG Y C
Sbjct: 1469 RDVALECQVKGTPFPDIHWFKDGKPLFLGDPNV---ELLDRGQVLHLKNARRNDKGRYQC 1525
Query: 140 IVENEYGSINHTYQLDVVERSPHRPILQAG-LPANKTVALGSNVEFMCKVYSDPQPHIQW 198
V N G +L + P ++ G + + +V + S ++ C+ P P I W
Sbjct: 1526 TVSNAAGKQAKDIKLTIY----IPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITW 1581
Query: 199 LK 200
K
Sbjct: 1582 YK 1583
Score = 40.4 bits (93), Expect = 0.002
Identities = 31/122 (25%), Positives = 53/122 (43%), Gaps = 7/122 (5%)
Query: 83 VKFKCPSSGTPNPTLRW--LKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCI 140
V C G P PT++W L N F + + T ++ + ++ SDKG Y C
Sbjct: 810 VTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSIS-QLRTGALFILNLWASDKGTYICE 868
Query: 141 VENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYS-DPQPHIQWL 199
EN++G I + V P++ P+ V G + C + + +P P +W+
Sbjct: 869 AENQFGKIQS--ETTVTVTGLVAPLIGIS-PSVANVIEGQQLTLPCTLLAGNPIPERRWI 925
Query: 200 KH 201
K+
Sbjct: 926 KN 927
Score = 39.7 bits (91), Expect = 0.003
Identities = 28/124 (22%), Positives = 46/124 (37%), Gaps = 15/124 (12%)
Query: 82 TVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIV 141
+V +C S+ P P + W KNG+ + ++ + + SD G Y C
Sbjct: 3076 SVSLECESNAVPPPVITWYKNGRMITESTHV---EILADGQMLHIKKAEVSDTGQYVCRA 3132
Query: 142 ENEYGSINHTYQLDVVE----RSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQ 197
N G + + L+V P R ++ + + V C P P I
Sbjct: 3133 INVAGRDDKNFHLNVYVPPSIEGPEREVI--------VETISNPVTLTCDATGIPPPTIA 3184
Query: 198 WLKH 201
WLK+
Sbjct: 3185 WLKN 3188
Score = 39.3 bits (90), Expect = 0.004
Identities = 28/114 (24%), Positives = 47/114 (41%), Gaps = 8/114 (7%)
Query: 87 CPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYG 146
C ++GTP+P + W K G G + + + V D G Y C+ +N G
Sbjct: 4009 CEATGTPSPFITWQKEGINVNTS---GRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAG 4065
Query: 147 SINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLK 200
+ +L+V + P P++ L +A+ + C+ P P I W K
Sbjct: 4066 TALGKIKLNV--QVP--PVISPHL-KEYVIAVDKPITLSCEADGLPPPDITWHK 4114
Score = 37.0 bits (84), Expect = 0.021
Identities = 24/121 (19%), Positives = 49/121 (40%), Gaps = 14/121 (11%)
Query: 87 CPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYG 146
C + P T+ W K+G + + I ++ ++ + + + G Y+C+ NE G
Sbjct: 2597 CEAYSYPPATITWFKDGTPLESNRNI---RILPGGRTLQILNAQEDNAGRYSCVATNEAG 2653
Query: 147 SINHTYQLDVVERSPHRPILQAG-------LPANKTVALGSNVEFMCKVYSDPQPHIQWL 199
+ Y++ V PI+ G P + + + + C+ Y+ P + W
Sbjct: 2654 EMIKHYEVKVY----IPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWY 2709
Query: 200 K 200
K
Sbjct: 2710 K 2710
Score = 33.9 bits (76), Expect = 0.18
Identities = 37/143 (25%), Positives = 57/143 (39%), Gaps = 14/143 (9%)
Query: 59 PVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVR 118
P AP T PEK + P + C TL +++NG D Y
Sbjct: 428 PDAPKVTMPEKTPG-YYLQPG----QIPCSVDSLLPFTLSFVRNGVTLGVDQ----YLKE 478
Query: 119 YATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVAL 178
A+ ++ + V SD+G Y CI + G+ DV E P++Q +P N TV
Sbjct: 479 SASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPP---PVIQ--VPNNVTVTP 533
Query: 179 GSNVEFMCKVYSDPQPHIQWLKH 201
G C + S ++ W ++
Sbjct: 534 GERAVLTCLIISAVDYNLTWQRN 556
Score = 33.5 bits (75), Expect = 0.23
Identities = 16/72 (22%), Positives = 29/72 (40%), Gaps = 4/72 (5%)
Query: 77 VPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGN 136
+ A + C ++G P PT+ W + G D R+ + S+ + D
Sbjct: 4451 INAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVN----VLSNNSLYIADAQKEDTSE 4506
Query: 137 YTCIVENEYGSI 148
+ C+ N GS+
Sbjct: 4507 FECVARNLMGSV 4518
>gi|7657359 contactin 5 isoform long [Homo sapiens]
Length = 1100
Score = 69.7 bits (169), Expect = 3e-12
Identities = 42/139 (30%), Positives = 66/139 (47%), Gaps = 11/139 (7%)
Query: 62 PYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYAT 121
P+W EK+ + + ++++C ++G P PT RWLKNG P R V
Sbjct: 390 PHWV--EKLNDT--QLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSR-----VEMVN 440
Query: 122 WSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSN 181
+++ +V SD G Y C+ EN+YG+I + +L ++ +P + Q L V
Sbjct: 441 GVLMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQ--LKKTIIVTKDQE 498
Query: 182 VEFMCKVYSDPQPHIQWLK 200
V CK P+P I W K
Sbjct: 499 VVIECKPQGSPKPTISWKK 517
Score = 46.2 bits (108), Expect = 3e-05
Identities = 42/144 (29%), Positives = 62/144 (43%), Gaps = 26/144 (18%)
Query: 77 VPAAK--TVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGY-----KVRYATWSIIMDSV 129
V AAK TVK +C + G P PT+ W+K + GY ++R + + + +V
Sbjct: 310 VTAAKGTTVKMECFALGNPVPTITWMK----------VNGYIPSKARLRKSQAVLEIPNV 359
Query: 130 VPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVY 189
D G Y C EN G + QL V PH + + GS + + CK
Sbjct: 360 QLDDAGIYECRAENSRGKNSFRGQLQVY-TYPH----WVEKLNDTQLDSGSPLRWECKAT 414
Query: 190 SDPQPHIQWLKHIEVNGSKIGPDN 213
P+P +WLK NG + P +
Sbjct: 415 GKPRPTYRWLK----NGVPLSPQS 434
Score = 44.3 bits (103), Expect = 1e-04
Identities = 34/120 (28%), Positives = 50/120 (41%), Gaps = 9/120 (7%)
Query: 72 KKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVP 131
KK V + V +C G+P PT+ W K + + + RI S+ + +
Sbjct: 488 KKTIIVTKDQEVVIECKPQGSPKPTISWKKGDRAVRENKRI----AILPDGSLRILNASK 543
Query: 132 SDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSD 191
SD+G Y C EN +GS L V E P R L P + +G ++ CK D
Sbjct: 544 SDEGKYVCRGENVFGSAEIIASLSVKE--PTRIEL---TPKRTELTVGESIVLNCKAIHD 598
Score = 42.4 bits (98), Expect = 5e-04
Identities = 26/70 (37%), Positives = 35/70 (50%), Gaps = 6/70 (8%)
Query: 81 KTVKFKCPSSGTPNPTLRWLKNGKE--FKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYT 138
K V C G P P+ RWL+NG E + D+R Y + T+ II + D G+Y
Sbjct: 117 KKVALNCEVRGNPVPSYRWLRNGTEIDLESDYR---YSLIDGTF-IISNPSEAKDSGHYQ 172
Query: 139 CIVENEYGSI 148
C+ N GSI
Sbjct: 173 CLATNTVGSI 182
Score = 38.1 bits (87), Expect = 0.010
Identities = 27/93 (29%), Positives = 42/93 (45%), Gaps = 11/93 (11%)
Query: 121 TWSIIMDSVVPSDKGNYTCIVENEYGSINH-------TYQLDVVERSPHRPILQAGLPAN 173
T ++ + V SD G+Y C+V+N + T + D V + P ++ P
Sbjct: 251 TGNLYISKVQTSDVGSYICLVKNTVTNARVLSPPTPLTLRNDGV-MGEYEPKIEVHFPFT 309
Query: 174 KTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNG 206
T A G+ V+ C +P P I W+K VNG
Sbjct: 310 VTAAKGTTVKMECFALGNPVPTITWMK---VNG 339
>gi|28373129 contactin 5 isoform short [Homo sapiens]
Length = 1026
Score = 69.7 bits (169), Expect = 3e-12
Identities = 42/139 (30%), Positives = 66/139 (47%), Gaps = 11/139 (7%)
Query: 62 PYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYAT 121
P+W EK+ + + ++++C ++G P PT RWLKNG P R V
Sbjct: 316 PHWV--EKLNDT--QLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSR-----VEMVN 366
Query: 122 WSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSN 181
+++ +V SD G Y C+ EN+YG+I + +L ++ +P + Q L V
Sbjct: 367 GVLMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQ--LKKTIIVTKDQE 424
Query: 182 VEFMCKVYSDPQPHIQWLK 200
V CK P+P I W K
Sbjct: 425 VVIECKPQGSPKPTISWKK 443
Score = 46.2 bits (108), Expect = 3e-05
Identities = 42/144 (29%), Positives = 62/144 (43%), Gaps = 26/144 (18%)
Query: 77 VPAAK--TVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGY-----KVRYATWSIIMDSV 129
V AAK TVK +C + G P PT+ W+K + GY ++R + + + +V
Sbjct: 236 VTAAKGTTVKMECFALGNPVPTITWMK----------VNGYIPSKARLRKSQAVLEIPNV 285
Query: 130 VPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVY 189
D G Y C EN G + QL V PH + + GS + + CK
Sbjct: 286 QLDDAGIYECRAENSRGKNSFRGQLQVY-TYPH----WVEKLNDTQLDSGSPLRWECKAT 340
Query: 190 SDPQPHIQWLKHIEVNGSKIGPDN 213
P+P +WLK NG + P +
Sbjct: 341 GKPRPTYRWLK----NGVPLSPQS 360
Score = 44.3 bits (103), Expect = 1e-04
Identities = 34/120 (28%), Positives = 50/120 (41%), Gaps = 9/120 (7%)
Query: 72 KKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVP 131
KK V + V +C G+P PT+ W K + + + RI S+ + +
Sbjct: 414 KKTIIVTKDQEVVIECKPQGSPKPTISWKKGDRAVRENKRI----AILPDGSLRILNASK 469
Query: 132 SDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSD 191
SD+G Y C EN +GS L V E P R L P + +G ++ CK D
Sbjct: 470 SDEGKYVCRGENVFGSAEIIASLSVKE--PTRIEL---TPKRTELTVGESIVLNCKAIHD 524
Score = 42.4 bits (98), Expect = 5e-04
Identities = 26/70 (37%), Positives = 35/70 (50%), Gaps = 6/70 (8%)
Query: 81 KTVKFKCPSSGTPNPTLRWLKNGKE--FKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYT 138
K V C G P P+ RWL+NG E + D+R Y + T+ II + D G+Y
Sbjct: 43 KKVALNCEVRGNPVPSYRWLRNGTEIDLESDYR---YSLIDGTF-IISNPSEAKDSGHYQ 98
Query: 139 CIVENEYGSI 148
C+ N GSI
Sbjct: 99 CLATNTVGSI 108
Score = 38.1 bits (87), Expect = 0.010
Identities = 27/93 (29%), Positives = 42/93 (45%), Gaps = 11/93 (11%)
Query: 121 TWSIIMDSVVPSDKGNYTCIVENEYGSINH-------TYQLDVVERSPHRPILQAGLPAN 173
T ++ + V SD G+Y C+V+N + T + D V + P ++ P
Sbjct: 177 TGNLYISKVQTSDVGSYICLVKNTVTNARVLSPPTPLTLRNDGV-MGEYEPKIEVHFPFT 235
Query: 174 KTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNG 206
T A G+ V+ C +P P I W+K VNG
Sbjct: 236 VTAAKGTTVKMECFALGNPVPTITWMK---VNG 265
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 68.6 bits (166), Expect = 7e-12
Identities = 41/125 (32%), Positives = 61/125 (48%), Gaps = 9/125 (7%)
Query: 77 VPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGN 136
V A+ TV +CP+ G P PT+ WL+NG F P R+ +V + + + +D +
Sbjct: 1666 VNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRL---QVLEDGQVLQVSTAEVADAAS 1722
Query: 137 YTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANK-TVALGSNVEFMCKVYSDPQPH 195
Y C+ EN+ GS + L V P AGL + T L S+V C V++ P P
Sbjct: 1723 YMCVAENQAGSAEKLFTLRV-----QVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPE 1777
Query: 196 IQWLK 200
+ W K
Sbjct: 1778 VTWYK 1782
Score = 61.2 bits (147), Expect = 1e-09
Identities = 35/118 (29%), Positives = 57/118 (48%), Gaps = 10/118 (8%)
Query: 83 VKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVE 142
V+ C + G P P + W+K+G+ G S+ +++V D G Y+C+
Sbjct: 2233 VELPCEARGVPLPLVSWMKDGEPLLSQSLEQGP-------SLQLEAVGAGDSGTYSCVAV 2285
Query: 143 NEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLK 200
+E G +QL V+E PH I +G P ++ G+ +E +C PQP+I W K
Sbjct: 2286 SEAGEARRHFQLTVME-PPH--IEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHK 2340
Score = 58.9 bits (141), Expect = 5e-09
Identities = 42/124 (33%), Positives = 58/124 (46%), Gaps = 5/124 (4%)
Query: 87 CPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYG 146
C + GTP P + W K G +P H G V S+ + SV P+D G+Y C NE G
Sbjct: 24 CGTHGTPKPQVTWRK-GPSSEPLHGQPGVAV-LEEGSLFLASVSPADSGDYECQATNEVG 81
Query: 147 SINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNG 206
S + +L VV P I + G AN + G ++ C P P I WLK ++ G
Sbjct: 82 STSRRAKL-VVYVPP--SIREDGRKANVSGMAGQSLTLECDANGFPVPEIVWLKDAQLVG 138
Query: 207 SKIG 210
+G
Sbjct: 139 VPLG 142
Score = 57.0 bits (136), Expect = 2e-08
Identities = 42/125 (33%), Positives = 57/125 (45%), Gaps = 15/125 (12%)
Query: 79 AAKTVKFKCPSSGTPNPTLRWLKNGKEFK---PDHRIGGYKVRYATWSIIMDSVVPSDKG 135
A + V C +SG P PT+ W K G + G ++R A S P D G
Sbjct: 2770 AEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHAS-------PEDAG 2822
Query: 136 NYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPH 195
NY CI +N GS +L V + P P+++ GLP T GS+ CK P+P+
Sbjct: 2823 NYLCIAKNSAGSAMGKTRL--VVQVP--PVIENGLPDLSTTE-GSHAFLPCKARGSPEPN 2877
Query: 196 IQWLK 200
I W K
Sbjct: 2878 ITWDK 2882
Score = 56.2 bits (134), Expect = 3e-08
Identities = 55/219 (25%), Positives = 86/219 (39%), Gaps = 8/219 (3%)
Query: 83 VKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVE 142
V+ C ++G P+PTL WLK+G P G +V + + S SD G Y+C+
Sbjct: 804 VRLTCNATGAPSPTLMWLKDGNPVSP-AGTPGLQVFPGGRVLTLASARASDSGRYSCVAV 862
Query: 143 NEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHI 202
+ G L V H P G N +V +V C+ ++ P P + W K
Sbjct: 863 SAVGEDRQDVVLQV-----HMPPSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDG 917
Query: 203 EVNGSKIGPDNLPYVQILKVIMAPVF-VGQSTGKETTVSGAQVPVGRLSCPRMGSFLTLQ 261
+ G +L+V A V+ G T + +G L+ F +
Sbjct: 918 RPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAGRSEKHYNLNVWVAPVFPLRE 977
Query: 262 AHTLHLSRDLATSPRTSNRGHKV-EVSWEQRAAGMGGAG 299
+HTL + TS RG ++SW + + G G
Sbjct: 978 SHTLTVREGHPTSLSCECRGVPFPKISWRKDGQPLPGEG 1016
Score = 55.1 bits (131), Expect = 8e-08
Identities = 36/130 (27%), Positives = 58/130 (44%), Gaps = 11/130 (8%)
Query: 75 HAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYAT--WSIIMDSVVPS 132
H V + V+ C + G P P + WLK+G D G +R+ S+++ + S
Sbjct: 2036 HHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDM---GPHLRFYLDGGSLVLKGLRAS 2092
Query: 133 DKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVAL--GSNVEFMCKVYS 190
D G YTC+ N G + ++V+ P ++ G + T+ G V +C V
Sbjct: 2093 DAGAYTCVAHNPAGEDARLHTVNVLV----PPTIKQGADGSGTLVSRPGELVTMVCPVRG 2148
Query: 191 DPQPHIQWLK 200
P H+ WLK
Sbjct: 2149 SPPIHVSWLK 2158
Score = 55.1 bits (131), Expect = 8e-08
Identities = 39/145 (26%), Positives = 65/145 (44%), Gaps = 14/145 (9%)
Query: 56 KPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGY 115
+P +AP SP + H PA C +SG+P P + W K+G++ + G Y
Sbjct: 2571 EPPAIAP---SPSNLTLTAHT-PAL----LPCEASGSPKPLVVWWKDGQKLDFRLQQGAY 2622
Query: 116 KVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKT 175
++ + ++++ + P D + C+V NE G + YQ+ V H P A + T
Sbjct: 2623 RLLPSN-ALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTV-----HVPPTIADDQTDFT 2676
Query: 176 VALGSNVEFMCKVYSDPQPHIQWLK 200
V + + V C P P + W K
Sbjct: 2677 VTMMAPVVLTCHSTGIPAPTVSWSK 2701
Score = 55.1 bits (131), Expect = 8e-08
Identities = 32/123 (26%), Positives = 52/123 (42%), Gaps = 9/123 (7%)
Query: 78 PAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNY 137
P +++ C G P P + W+K+G + H + + S+ + D G Y
Sbjct: 3040 PVGGSIQLDCVVRGDPVPDIHWIKDGLPLRGSH----LRHQLQNGSLTIHRTERDDAGRY 3095
Query: 138 TCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQ 197
C+ ENE G V+ P+ Q P + TV G +V C+ +P P I+
Sbjct: 3096 QCLAENEMGVAKKV----VILVLQSAPVFQVE-PQDMTVRSGDDVALRCQATGEPTPTIE 3150
Query: 198 WLK 200
WL+
Sbjct: 3151 WLQ 3153
Score = 54.3 bits (129), Expect = 1e-07
Identities = 32/117 (27%), Positives = 56/117 (47%), Gaps = 7/117 (5%)
Query: 87 CPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYG 146
C + P+P + W+K+G F+ I ++ T + + + D G YTC+V NE G
Sbjct: 1372 CEALAFPSPNITWMKDGAPFEASRNI---QLLPGTHGLQILNAQKEDAGQYTCVVTNELG 1428
Query: 147 SINHTYQLDVV---ERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLK 200
Y ++V+ S P+ + G+ KT + S + C+ ++ P P I+W K
Sbjct: 1429 EAVKNYHVEVLIPPSISKDDPLGEVGVKEVKT-KVNSTLTLECESWAVPPPTIRWYK 1484
Score = 53.9 bits (128), Expect = 2e-07
Identities = 51/177 (28%), Positives = 72/177 (40%), Gaps = 23/177 (12%)
Query: 76 AVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKG 135
AV +V +C +SG P P + W K +P G V + ++ SD G
Sbjct: 705 AVLENASVTLECLASGVPPPDVSWFKG---HQPVSSWMGVTVSVDGRVLRIEQAQLSDAG 761
Query: 136 NYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPH 195
+Y C+ N GS Y L V P R L LP V + + V C P P
Sbjct: 762 SYRCVASNVAGSTELRYGLRV--NVPPRITLPPSLPG--PVLVNTPVRLTCNATGAPSPT 817
Query: 196 IQWLKHIEVNGSKIGPDNLPYVQILKVIMAPVFVGQSTGKETTVSGAQV-PVGRLSC 251
+ WLK +G+ + P P +Q VF G G+ T++ A+ GR SC
Sbjct: 818 LMWLK----DGNPVSPAGTPGLQ--------VFPG---GRVLTLASARASDSGRYSC 859
Score = 52.0 bits (123), Expect = 6e-07
Identities = 37/140 (26%), Positives = 59/140 (42%), Gaps = 10/140 (7%)
Query: 79 AAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYT 138
A + C SG P PT+ WLK+ P + V + + + P+ G YT
Sbjct: 1947 AGSPLVLTCDVSGVPAPTVTWLKDRM---PVESSAVHGVVSRGGRLQLSRLQPAQAGTYT 2003
Query: 139 CIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQW 198
C+ EN + + V+ +P I +G+ V G V C+ P P + W
Sbjct: 2004 CVAENTQAEARKDFVVAVLV-APR--IRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAW 2060
Query: 199 LKHIEVNGSKIGPDNLPYVQ 218
LK +GS +G D P+++
Sbjct: 2061 LK----DGSPLGQDMGPHLR 2076
Score = 49.3 bits (116), Expect = 4e-06
Identities = 29/114 (25%), Positives = 42/114 (36%), Gaps = 6/114 (5%)
Query: 87 CPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYG 146
C + G P P +RW + + P + W + M D G Y+C+ NE G
Sbjct: 1183 CEAMGIPPPAIRWFRGEEPVSPGEDT---YLLAGGWMLKMTQTQEQDSGLYSCLASNEAG 1239
Query: 147 SINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLK 200
+ ++V+ I L V G MC V PQP + W K
Sbjct: 1240 EARRNFSVEVLVPP---SIENEDLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFK 1290
Score = 48.1 bits (113), Expect = 9e-06
Identities = 29/115 (25%), Positives = 54/115 (46%), Gaps = 5/115 (4%)
Query: 86 KCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEY 145
+C ++G P PT+ W ++G+ + G +++ S+ ++ + G Y+C+ EN
Sbjct: 1088 ECNATGKPPPTVTWERDGQPVGAEL---GLQLQNQGQSLHVERAQAAHTGRYSCVAENLA 1144
Query: 146 GSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLK 200
G ++L V+ P I N T AL S + +C+ P P I+W +
Sbjct: 1145 GRAERKFELSVLV--PPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFR 1197
Score = 47.8 bits (112), Expect = 1e-05
Identities = 28/112 (25%), Positives = 47/112 (41%), Gaps = 8/112 (7%)
Query: 87 CPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYG 146
C + G+P P + W K+G+ P G + +++ ++ D G YTC EN G
Sbjct: 2868 CKARGSPEPNITWDKDGQ---PVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVG 2924
Query: 147 SINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQW 198
L ++ P+ LP ++++ LG + C P P I W
Sbjct: 2925 RARRRVHLTILVL----PVFTT-LPGDRSLRLGDRLWLRCAARGSPTPRIGW 2971
Score = 47.0 bits (110), Expect = 2e-05
Identities = 41/173 (23%), Positives = 78/173 (45%), Gaps = 12/173 (6%)
Query: 79 AAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYT 138
A + V +C + G P+PTL W G P ++ + ++S + G Y+
Sbjct: 419 AGRPVALECVARGHPSPTLSWHHEGL---PVAESNESRLETDGSVLRLESPGEASSGLYS 475
Query: 139 CIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQW 198
C+ + G Y ++V + P + ++ GL T +G +E C+ P P IQW
Sbjct: 476 CVASSPAGEAVLQYSVEV--QVPPQLLVAEGL-GQVTTIVGQPLELPCQASGSPVPTIQW 532
Query: 199 LKH----IEVNGSKIGPDNLP-YVQILKVIMAPVFVGQSTGKETTVSGAQVPV 246
L++ E+ G ++ ++ +++ + +F Q+T E +GA+V V
Sbjct: 533 LQNGRPAEELAGVQVASQGTTLHIDHVELDHSGLFACQAT-NEAGTAGAEVEV 584
Score = 46.6 bits (109), Expect = 3e-05
Identities = 31/117 (26%), Positives = 48/117 (41%), Gaps = 13/117 (11%)
Query: 86 KCPSSGTPNPTLRWLKNGKEFKP--DHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVEN 143
+C + G+P P + W N + + GG ++ A +V D G Y C EN
Sbjct: 2958 RCAARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRA-------AVSREDSGTYVCWAEN 3010
Query: 144 EYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLK 200
G + V E P+LQ + +G +++ C V DP P I W+K
Sbjct: 3011 RVGRTQAVSFVHVKEA----PVLQGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIK 3063
Score = 46.2 bits (108), Expect = 3e-05
Identities = 34/118 (28%), Positives = 50/118 (42%), Gaps = 8/118 (6%)
Query: 83 VKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVE 142
V C S+G P PT+ W K G + R GY+V + ++ + +P G YTC
Sbjct: 2683 VVLTCHSTGIPAPTVSWSKAGAQL--GARGSGYRVS-PSGALEIGQALPIHAGRYTCSAR 2739
Query: 143 NEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLK 200
N G + H + V+ SP + LP+ V C+ P+P I W K
Sbjct: 2740 NSAG-VAHKHVFLTVQASP----VVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQK 2792
Score = 46.2 bits (108), Expect = 3e-05
Identities = 40/182 (21%), Positives = 75/182 (41%), Gaps = 14/182 (7%)
Query: 69 KMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDS 128
++E + V + V +C ++G P PT+ WL+ G+ + R+ S+ +++
Sbjct: 3121 QVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLR----TLPDGSLWLEN 3176
Query: 129 VVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRP--ILQAGLPANKTVALGSNVEFMC 186
V D G Y C+ N GS L VV P + + K N M
Sbjct: 3177 VETGDAGTYDCVAHNLLGSATARAFL-VVRGEPQGSWGSMTGVINGRKFGVATLNTSVMQ 3235
Query: 187 KVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKVIMAPVFVGQSTGKETTVSGAQVPV 246
+ +S ++H+ N +G P +++L V +AP++ + ++G +
Sbjct: 3236 EAHSGVSSIHSSIRHVPAN---VG----PLMRVLVVTIAPIYWALARESGEALNGHSLTG 3288
Query: 247 GR 248
GR
Sbjct: 3289 GR 3290
Score = 45.8 bits (107), Expect = 5e-05
Identities = 30/122 (24%), Positives = 48/122 (39%), Gaps = 7/122 (5%)
Query: 81 KTVKFKCPSSGTPNPTLRWLKNGKEFKPD--HRIGGYKVRYATWSIIMDSVVPSDKGNYT 138
+T C +G P P L W K+G+ H I V + S G+Y+
Sbjct: 1270 QTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSA-----GHYS 1324
Query: 139 CIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQW 198
CI N G +QL V+ + TV + + + +C+ + P P+I W
Sbjct: 1325 CIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITW 1384
Query: 199 LK 200
+K
Sbjct: 1385 MK 1386
Score = 45.1 bits (105), Expect = 8e-05
Identities = 32/124 (25%), Positives = 51/124 (41%), Gaps = 8/124 (6%)
Query: 77 VPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGN 136
V +T C + G P P + W K+ P R +++ S+ + V+ D G+
Sbjct: 2493 VSVNQTALLPCQADGVPAPLVSWRKDRVPLDP--RSPRFEI-LPEGSLRIQPVLAQDAGH 2549
Query: 137 YTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHI 196
Y C+ N GS L V+E P A P+N T+ + C+ P+P +
Sbjct: 2550 YLCLASNSAGSDRQGRDLRVLE-----PPAIAPSPSNLTLTAHTPALLPCEASGSPKPLV 2604
Query: 197 QWLK 200
W K
Sbjct: 2605 VWWK 2608
Score = 44.7 bits (104), Expect = 1e-04
Identities = 34/125 (27%), Positives = 49/125 (39%), Gaps = 7/125 (5%)
Query: 76 AVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKG 135
+V A ++V +C S P P L W K+G+ +P G + + +D D G
Sbjct: 890 SVVANESVALECQSHAMPPPVLSWWKDGRPLEPR---PGVHLSADKALLQVDRADVWDAG 946
Query: 136 NYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPH 195
+YTC N+ G Y L+V P+ TV G C+ P P
Sbjct: 947 HYTCEALNQAGRSEKHYNLNVWV----APVFPLRESHTLTVREGHPTSLSCECRGVPFPK 1002
Query: 196 IQWLK 200
I W K
Sbjct: 1003 ISWRK 1007
Score = 43.5 bits (101), Expect = 2e-04
Identities = 35/118 (29%), Positives = 50/118 (42%), Gaps = 15/118 (12%)
Query: 87 CPSSGTPNPTLRWLKNGKEFKPDHRI----GGYKVRYATWSIIMDSVVPSDKGNYTCIVE 142
C + P PT+ W K+G+ R GG ++ I ++ V SDKG Y+C V
Sbjct: 1863 CETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLE------IQEAQV-SDKGLYSCKVS 1915
Query: 143 NEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLK 200
N G T+ L V + P P + + GS + C V P P + WLK
Sbjct: 1916 NVAGEAVRTFTLTV--QVP--PTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLK 1969
Score = 42.7 bits (99), Expect = 4e-04
Identities = 44/162 (27%), Positives = 62/162 (38%), Gaps = 30/162 (18%)
Query: 64 WTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRI----GGYKVRY 119
W S E E AV V+ C + G P P + W K+G ++ GG +++
Sbjct: 313 WGSNETGEV---AVMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQ- 368
Query: 120 ATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDV-----VERSPHRPILQAGLPANK 174
+ SD G YTC N G+ +LDV +E + RP + K
Sbjct: 369 ------LGRAQSSDAGVYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVV------K 416
Query: 175 TVALGSNVEFMCKVYSDPQPHIQW----LKHIEVNGSKIGPD 212
VA G V C P P + W L E N S++ D
Sbjct: 417 AVA-GRPVALECVARGHPSPTLSWHHEGLPVAESNESRLETD 457
Score = 42.4 bits (98), Expect = 5e-04
Identities = 21/74 (28%), Positives = 38/74 (51%), Gaps = 3/74 (4%)
Query: 83 VKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVE 142
++ C +SG+P PT++WL+NG +P + G +V ++ +D V G + C
Sbjct: 516 LELPCQASGSPVPTIQWLQNG---RPAEELAGVQVASQGTTLHIDHVELDHSGLFACQAT 572
Query: 143 NEYGSINHTYQLDV 156
NE G+ ++ V
Sbjct: 573 NEAGTAGAEVEVSV 586
Score = 41.6 bits (96), Expect = 9e-04
Identities = 34/152 (22%), Positives = 56/152 (36%), Gaps = 11/152 (7%)
Query: 64 WTSPEKMEKKLHAVPAAK--TVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYAT 121
W +P ++ H + + C G P P + W K+G+ P G V
Sbjct: 968 WVAPVFPLRESHTLTVREGHPTSLSCECRGVPFPKISWRKDGQPL-PGEGAGLQHVSAVG 1026
Query: 122 WSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAG---LPANKTVAL 178
+ + + +G YTC N G+ + QL+V H P AG P +V
Sbjct: 1027 RLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEV-----HVPPQIAGPREPPTQVSVVQ 1081
Query: 179 GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIG 210
C P P + W + + G+++G
Sbjct: 1082 DGVATLECNATGKPPPTVTWERDGQPVGAELG 1113
Score = 41.6 bits (96), Expect = 9e-04
Identities = 34/123 (27%), Positives = 53/123 (43%), Gaps = 16/123 (13%)
Query: 83 VKFKCPSSGTPNPTLRWLKNGKEFKPDHRI----GGYKVRYATWSIIMDSVVPSDKGNYT 138
V CP G+P + WLK+G R G+ +R + V +D G +T
Sbjct: 2140 VTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLR-------ISKVQLADAGIFT 2192
Query: 139 CIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVAL-GSNVEFMCKVYSDPQPHIQ 197
C+ + G + + L V + P P+L+ N V + GS VE C+ P P +
Sbjct: 2193 CVAASPAGVADRNFTLQV--QVP--PVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVS 2248
Query: 198 WLK 200
W+K
Sbjct: 2249 WMK 2251
Score = 41.2 bits (95), Expect = 0.001
Identities = 33/130 (25%), Positives = 51/130 (39%), Gaps = 22/130 (16%)
Query: 73 KLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPS 132
+L P A ++ C + GTP P + W K+G+ R S +
Sbjct: 2313 ELSLTPGAP-MELLCDAQGTPQPNITWHKDGQAL----------TRLENNSRATRVLRVR 2361
Query: 133 DKGNYTCIVENEYGSINHTYQLDVVER----SPHRPILQAGLPANKTVALGSNVEFMCKV 188
D G YTC+ E+ G+I ++++ V P P GL + V C V
Sbjct: 2362 DAGLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLV-------LECSV 2414
Query: 189 YSDPQPHIQW 198
++P P I W
Sbjct: 2415 EAEPAPKITW 2424
Score = 40.4 bits (93), Expect = 0.002
Identities = 33/126 (26%), Positives = 53/126 (42%), Gaps = 13/126 (10%)
Query: 79 AAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGG--YKVRYATWSIIMDSVVPSDKGN 136
A V+ +C +SG P P + W K+ + P GG +V+ + + D+G
Sbjct: 231 AGADVELQCWTSGVPTPQVEWTKDRQPVLP----GGPHLQVQEDGQVLRITGSHVGDEGR 286
Query: 137 YTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSN--VEFMCKVYSDPQP 194
Y C+ + G +QL V H P G VA+ + V+ +C+ P P
Sbjct: 287 YQCVAFSPAGQQARDFQLRV-----HAPPTIWGSNETGEVAVMEDHLVQLLCEARGVPTP 341
Query: 195 HIQWLK 200
+I W K
Sbjct: 342 NITWFK 347
Score = 38.9 bits (89), Expect = 0.006
Identities = 35/178 (19%), Positives = 70/178 (39%), Gaps = 21/178 (11%)
Query: 82 TVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIV 141
T+ +C S P PT+RW K+G+ P R+ +V + + SD G Y C+
Sbjct: 1465 TLTLECESWAVPPPTIRWYKDGQPVTPSSRL---QVLGEGRLLQIQPTQVSDSGRYLCVA 1521
Query: 142 ENEYGSINHTYQL---------DVVERSPHRPIL------QAGLPANKTVALGSNVEFMC 186
N G + + + V + S IL + G+ + + + C
Sbjct: 1522 TNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLYC 1581
Query: 187 KVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKVIMAPVFVGQSTGKETTVSGAQV 244
+ P P + W + + + D + +Q +V+ P+ ++ G+ + + +V
Sbjct: 1582 DTNAIPPPDLTWYREDQPLSA---GDEVSVLQGGRVLQIPLVRAENAGRYSCKASNEV 1636
Score = 37.0 bits (84), Expect = 0.021
Identities = 34/138 (24%), Positives = 52/138 (37%), Gaps = 16/138 (11%)
Query: 87 CPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYG 146
C ++ P P L W + + + V + + V + G Y+C NE G
Sbjct: 1581 CDTNAIPPPDLTWYREDQPLSAGDEVS---VLQGGRVLQIPLVRAENAGRYSCKASNEVG 1637
Query: 147 SINHTYQLDVVERSPHRPILQAG---LPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIE 203
Y+L V+ P++ L TV S V C +P P I WL+
Sbjct: 1638 EDWLHYELLVLTP----PVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISWLQ--- 1690
Query: 204 VNGSKIGPDNLPYVQILK 221
NG P P +Q+L+
Sbjct: 1691 -NGLPFSPS--PRLQVLE 1705
Score = 37.0 bits (84), Expect = 0.021
Identities = 26/117 (22%), Positives = 53/117 (45%), Gaps = 12/117 (10%)
Query: 86 KCPSSGTPNPTLRWLKNGKEFKPD-HRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENE 144
+C P P + W ++G + D H + R+ + + ++ +D G+Y+C N
Sbjct: 2411 ECSVEAEPAPKITWHRDGIVLQEDAHTQFPERGRF----LQLQALSTADSGDYSCTARNA 2466
Query: 145 YGSINHTYQLDVVERSPHR-PILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLK 200
GS + +++++ H P +++G PA V++ C+ P P + W K
Sbjct: 2467 AGSTSVAFRVEI-----HTVPTIRSGPPA-VNVSVNQTALLPCQADGVPAPLVSWRK 2517
Score = 36.2 bits (82), Expect = 0.036
Identities = 28/119 (23%), Positives = 44/119 (36%), Gaps = 4/119 (3%)
Query: 82 TVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIV 141
+V C PNP + W K+ + + + T ++ + SD G YTC
Sbjct: 1763 SVSLPCDVHAHPNPEVTWYKDSQALSLGEEVF---LLPGTHTLQLGRARLSDSGMYTCEA 1819
Query: 142 ENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLK 200
N G QL V+ R + A V +G C+ + P+P + W K
Sbjct: 1820 LNAAGRDQKLVQLSVLVPPAFRQAPRGPQDA-VLVRVGDKAVLSCETDALPEPTVTWYK 1877
Score = 33.5 bits (75), Expect = 0.23
Identities = 21/68 (30%), Positives = 28/68 (41%), Gaps = 5/68 (7%)
Query: 133 DKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDP 192
D+G YTC N G L V+ P ++ G P NK V ++V C P
Sbjct: 668 DEGIYTCAATNLAGESKREVALKVLVP----PNIEPG-PVNKAVLENASVTLECLASGVP 722
Query: 193 QPHIQWLK 200
P + W K
Sbjct: 723 PPDVSWFK 730
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.131 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,999,364
Number of Sequences: 37866
Number of extensions: 727641
Number of successful extensions: 7507
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 249
Number of HSP's successfully gapped in prelim test: 250
Number of HSP's that attempted gapping in prelim test: 4126
Number of HSP's gapped (non-prelim): 2343
length of query: 300
length of database: 18,247,518
effective HSP length: 102
effective length of query: 198
effective length of database: 14,385,186
effective search space: 2848266828
effective search space used: 2848266828
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.