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Search of human proteins with 4504657
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4504657 interleukin 18 receptor accessory protein precursor
[Homo sapiens]
(599 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4504657 interleukin 18 receptor accessory protein precursor [... 1222 0.0
gi|11225607 interleukin 1 receptor accessory protein-like 2 [Hom... 214 2e-55
gi|7657232 interleukin 1 receptor accessory protein-like 1 precu... 194 2e-49
gi|4504661 interleukin 1 receptor accessory protein isoform 1 [H... 181 1e-45
gi|4504655 interleukin 18 receptor 1 precursor [Homo sapiens] 170 3e-42
gi|27894324 interleukin 1 receptor-like 1 isoform 1 precursor [H... 145 1e-34
gi|4504659 interleukin 1 receptor, type I precursor [Homo sapiens] 136 6e-32
gi|28416902 interleukin 1 receptor-like 2 precursor [Homo sapiens] 119 8e-27
gi|27894334 interleukin 1 receptor, type II precursor [Homo sapi... 78 2e-14
gi|4758598 interleukin 1 receptor, type II precursor [Homo sapiens] 78 2e-14
gi|205277451 single Ig IL-1R-related molecule [Homo sapiens] 68 2e-11
gi|205277449 single Ig IL-1R-related molecule [Homo sapiens] 68 2e-11
gi|205277445 single Ig IL-1R-related molecule [Homo sapiens] 68 2e-11
gi|19882209 interleukin 1 receptor accessory protein isoform 2 [... 68 3e-11
gi|27894328 interleukin 1 receptor-like 1 isoform 2 precursor [H... 54 5e-07
gi|41350337 toll-like receptor 1 [Homo sapiens] 53 7e-07
gi|20143971 toll-like receptor 6 [Homo sapiens] 51 3e-06
gi|62865621 toll-like receptor 10 precursor [Homo sapiens] 45 2e-04
gi|62865618 toll-like receptor 10 precursor [Homo sapiens] 45 2e-04
gi|126517478 peroxidasin homolog-like [Homo sapiens] 44 6e-04
gi|19718734 toll-like receptor 2 [Homo sapiens] 43 7e-04
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 43 7e-04
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 43 7e-04
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 43 7e-04
gi|148886752 immunoglobulin superfamily, member 9B [Homo sapiens] 40 0.005
gi|20302168 toll-like receptor 8 [Homo sapiens] 39 0.014
gi|4507531 toll-like receptor 3 [Homo sapiens] 38 0.023
gi|118572606 hemicentin 1 [Homo sapiens] 38 0.030
gi|94420689 neural cell adhesion molecule 1 isoform 1 [Homo sapi... 38 0.030
gi|115529478 neural cell adhesion molecule 1 isoform 3 [Homo sap... 38 0.030
>gi|4504657 interleukin 18 receptor accessory protein precursor
[Homo sapiens]
Length = 599
Score = 1222 bits (3163), Expect = 0.0
Identities = 599/599 (100%), Positives = 599/599 (100%)
Query: 1 MLCLGWIFLWLVAGERIKGFNISGCSTKKLLWTYSTRSEEEFVLFCDLPEPQKSHFCHRN 60
MLCLGWIFLWLVAGERIKGFNISGCSTKKLLWTYSTRSEEEFVLFCDLPEPQKSHFCHRN
Sbjct: 1 MLCLGWIFLWLVAGERIKGFNISGCSTKKLLWTYSTRSEEEFVLFCDLPEPQKSHFCHRN 60
Query: 61 RLSPKQVPEHLPFMGSNDLSDVQWYQQPSNGDPLEDIRKSYPHIIQDKCTLHFLTPGVNN 120
RLSPKQVPEHLPFMGSNDLSDVQWYQQPSNGDPLEDIRKSYPHIIQDKCTLHFLTPGVNN
Sbjct: 61 RLSPKQVPEHLPFMGSNDLSDVQWYQQPSNGDPLEDIRKSYPHIIQDKCTLHFLTPGVNN 120
Query: 121 SGSYICRPKMIKSPYDVACCVKMILEVKPQTNASCEYSASHKQDLLLGSTGSISCPSLSC 180
SGSYICRPKMIKSPYDVACCVKMILEVKPQTNASCEYSASHKQDLLLGSTGSISCPSLSC
Sbjct: 121 SGSYICRPKMIKSPYDVACCVKMILEVKPQTNASCEYSASHKQDLLLGSTGSISCPSLSC 180
Query: 181 QSDAQSPAVTWYKNGKLLSVERSNRIVVDEVYDYHQGTYVCDYTQSDTVSSWTVRAVVQV 240
QSDAQSPAVTWYKNGKLLSVERSNRIVVDEVYDYHQGTYVCDYTQSDTVSSWTVRAVVQV
Sbjct: 181 QSDAQSPAVTWYKNGKLLSVERSNRIVVDEVYDYHQGTYVCDYTQSDTVSSWTVRAVVQV 240
Query: 241 RTIVGDTKLKPDILDPVEDTLEVELGKPLTISCKARFGFERVFNPVIKWYIKDSDLEWEV 300
RTIVGDTKLKPDILDPVEDTLEVELGKPLTISCKARFGFERVFNPVIKWYIKDSDLEWEV
Sbjct: 241 RTIVGDTKLKPDILDPVEDTLEVELGKPLTISCKARFGFERVFNPVIKWYIKDSDLEWEV 300
Query: 301 SVPEAKSIKSTLKDEIIERNIILEKVTQRDLRRKFVCFVQNSIGNTTQSVQLKEKRGVVL 360
SVPEAKSIKSTLKDEIIERNIILEKVTQRDLRRKFVCFVQNSIGNTTQSVQLKEKRGVVL
Sbjct: 301 SVPEAKSIKSTLKDEIIERNIILEKVTQRDLRRKFVCFVQNSIGNTTQSVQLKEKRGVVL 360
Query: 361 LYILLGTIGTLVAVLAASALLYRHWIEIVLLYRTYQSKDQTLGDKKDFDAFVSYAKWSSF 420
LYILLGTIGTLVAVLAASALLYRHWIEIVLLYRTYQSKDQTLGDKKDFDAFVSYAKWSSF
Sbjct: 361 LYILLGTIGTLVAVLAASALLYRHWIEIVLLYRTYQSKDQTLGDKKDFDAFVSYAKWSSF 420
Query: 421 PSEATSSLSEEHLALSLFPDVLENKYGYSLCLLERDVAPGGVYAEDIVSIIKRSRRGIFI 480
PSEATSSLSEEHLALSLFPDVLENKYGYSLCLLERDVAPGGVYAEDIVSIIKRSRRGIFI
Sbjct: 421 PSEATSSLSEEHLALSLFPDVLENKYGYSLCLLERDVAPGGVYAEDIVSIIKRSRRGIFI 480
Query: 481 LSPNYVNGPSIFELQAAVNLALDDQTLKLILIKFCYFQEPESLPHLVKKALRVLPTVTWR 540
LSPNYVNGPSIFELQAAVNLALDDQTLKLILIKFCYFQEPESLPHLVKKALRVLPTVTWR
Sbjct: 481 LSPNYVNGPSIFELQAAVNLALDDQTLKLILIKFCYFQEPESLPHLVKKALRVLPTVTWR 540
Query: 541 GLKSVPPNSRFWAKMRYHMPVKNSQGFTWNQLRITSRIFQWKGLSRTETTGRSSQPKEW 599
GLKSVPPNSRFWAKMRYHMPVKNSQGFTWNQLRITSRIFQWKGLSRTETTGRSSQPKEW
Sbjct: 541 GLKSVPPNSRFWAKMRYHMPVKNSQGFTWNQLRITSRIFQWKGLSRTETTGRSSQPKEW 599
>gi|11225607 interleukin 1 receptor accessory protein-like 2 [Homo
sapiens]
Length = 686
Score = 214 bits (544), Expect = 2e-55
Identities = 154/506 (30%), Positives = 255/506 (50%), Gaps = 39/506 (7%)
Query: 82 VQWYQQPSNGDPLEDIRKSYPHIIQDKCTLHFLTPGVNNSGSYICRPKMIKSPYDVACCV 141
+ WY+ + GD E I S + +++ ++ F + +SG Y C + S Y + V
Sbjct: 74 LMWYK--NKGDLEEPIIFSEVRMSKEEDSIWFHSAEAQDSGFYTC--VLRNSTYCMK--V 127
Query: 142 KMILEVKPQTNASCEYSA-SHKQDLLLGSTGSISCPSLS-CQSDAQSPAVTWYKNGK--- 196
M L V + C S + + + ISCP + + Q P V WYK K
Sbjct: 128 SMSLTVAENESGLCYNSRIRYLEKSEVTKRKEISCPDMDDFKKSDQEPDVVWYKECKPKM 187
Query: 197 --LLSVERSNRIVVDEVYDYHQGTYVCDYTQSDTVSSWTVRAVVQVRTIVGDTKLKPDIL 254
+ +++ N +++ EV + G Y C+ + VR +++ T P L
Sbjct: 188 WRSIIIQKGNALLIQEVQEEDGGNYTCELKYEGKL----VRRTTELKVTALLTDKPPKPL 243
Query: 255 DPVED---TLEVELGKPLTISCKARFGFERVFNPVIKWYIKDS---DLEWEVSVPEAKSI 308
P+E+ ++V+LGKPL I CKA FGF P+I W + +L + E + +
Sbjct: 244 FPMENQPSVIDVQLGKPLNIPCKAFFGFSGESGPMIYWMKGEKFIEELAGHIREGEIRLL 303
Query: 309 KSTLKDEIIERNIILEKVTQRDLRRKFVCFVQNSIGNTTQSVQLKEKRGVVLLYILLGTI 368
K L ++ +E +I + V + DL + C V+N G SV L+ K+ ++ L G +
Sbjct: 304 KEHLGEKEVELALIFDSVVEADLAN-YTCHVENRNGRKHASVLLR-KKDLIYKIELAGGL 361
Query: 369 GTLVAVLAASALLYRHW-IEIVLLYRTYQSKDQTLGDKKDFDAFVSYAKWSSFPSEATSS 427
G + +L ++Y+ + IE++L YR + D+T D K++DA++SY K + +
Sbjct: 362 GAIFLLLVLLVVIYKCYNIELMLFYRQHFGADETNDDNKEYDAYLSYTKVDQDTLDCDNP 421
Query: 428 LSEEHLALSLFPDVLENKYGYSLCLLERDVAPGGVYAEDIVSIIKRSRRGIFILSPNYV- 486
EE AL + PDVLE YGY L + ERD+ P G Y ED+ +++SRR I +L+P+Y+
Sbjct: 422 -EEEQFALEVLPDVLEKHYGYKLFIPERDLIPSGTYMEDLTRYVEQSRRLIIVLTPDYIL 480
Query: 487 -NGPSIFELQAAVNLALDDQTLKLILIKFCYF------QEPESLPHLVKKALRVLPTVTW 539
G SIFEL++ ++ L +K+ILI+ QE ESL K+++++L + W
Sbjct: 481 RRGWSIFELESRLHNMLVSGEIKVILIECTELKGKVNCQEVESL----KRSIKLLSLIKW 536
Query: 540 RGLKSVPPNSRFWAKMRYHMPVKNSQ 565
+G KS NS+FW + Y MP+K +
Sbjct: 537 KGSKSSKLNSKFWKHLVYEMPIKKKE 562
>gi|7657232 interleukin 1 receptor accessory protein-like 1
precursor [Homo sapiens]
Length = 696
Score = 194 bits (493), Expect = 2e-49
Identities = 151/520 (29%), Positives = 251/520 (48%), Gaps = 52/520 (10%)
Query: 82 VQWYQQPSNGDPLEDIRKSYPHIIQDKCTLHFLTPGVNNSGSYICRPKMIKSPYDVACCV 141
+ WY+ GD E I + +++ ++ F + +SG Y C + S Y + V
Sbjct: 74 LMWYKSSGPGDFEEPIAFDGSRMSKEEDSIWFRPTLLQDSGLYACVIR--NSTYCMK--V 129
Query: 142 KMILEVKPQTNASCEYSASHK--QDLLLGSTGSISCPSLS-CQSDAQSPAVTWYKNGKLL 198
+ L V C Y++ K + L + ISC + + P + WYK +
Sbjct: 130 SISLTVGENDTGLC-YNSKMKYFEKAELSKSKEISCRDIEDFLLPTREPEILWYKECRTK 188
Query: 199 S-----VERSNRIVVDEVYDYHQGTYVCDYTQSDTVSSWTVRAVVQVRTIVGDTKLKPDI 253
+ V + + +++ EV + G Y C+ V VR ++ T P +
Sbjct: 189 TWRPSIVFKRDTLLIREVREDDIGNYTCELKYGGFV----VRRTTELTVTAPLTDKPPKL 244
Query: 254 LDPVEDTL---EVELGKPLTISCKARFGFERVFNPVIKW-----YIKDSDLEWEVSVPEA 305
L P+E L E +LG ++C+A FG+ +P+I W +I+D D E V +
Sbjct: 245 LYPMESKLTIQETQLGDSANLTCRAFFGYSGDVSPLIYWMKGEKFIEDLD-ENRVWESDI 303
Query: 306 KSIKSTLKDEIIERNIILEKVTQRDLRRKFVCFVQNSIGNTTQSVQLKEKRGVVLLYILL 365
+ +K L ++ + ++I++ V + DL + C+V+N G SV L KR ++ L
Sbjct: 304 RILKEHLGEQEVSISLIVDSVEEGDLGN-YSCYVENGNGRRHASVLL-HKRELMYTVELA 361
Query: 366 GTIGTLVAVLAASALLYRHW-IEIVLLYRTYQSKDQTLGDKKDFDAFVSYAK-----WSS 419
G +G ++ +L +Y+ + IEI+L YR + ++ GD KD+DA++SY K W+
Sbjct: 362 GGLGAILLLLVCLVTIYKCYKIEIMLFYRNHFGAEELDGDNKDYDAYLSYTKVDPDQWNQ 421
Query: 420 FPSEATSSLSEEHLALSLFPDVLENKYGYSLCLLERDVAPGGVYAEDIVSIIKRSRRGIF 479
E EE AL + PD+LE YGY L + +RD+ P G Y ED+ + +S+R I
Sbjct: 422 ETGE------EERFALEILPDMLEKHYGYKLFIPDRDLIPTGTYIEDVARCVDQSKRLII 475
Query: 480 ILSPNYV--NGPSIFELQAAVNLALDDQTLKLILIK------FCYFQEPESLPHLVKKAL 531
+++PNYV G SIFEL+ + L +K+ILI+ +QE E+L H +K
Sbjct: 476 VMTPNYVVRRGWSIFELETRLRNMLVTGEIKVILIECSELRGIMNYQEVEALKHTIK--- 532
Query: 532 RVLPTVTWRGLKSVPPNSRFWAKMRYHMPVKNSQGFTWNQ 571
+L + W G K NS+FW +++Y MP K + T Q
Sbjct: 533 -LLTVIKWHGPKCNKLNSKFWKRLQYEMPFKRIEPITHEQ 571
>gi|4504661 interleukin 1 receptor accessory protein isoform 1 [Homo
sapiens]
Length = 570
Score = 181 bits (460), Expect = 1e-45
Identities = 143/523 (27%), Positives = 244/523 (46%), Gaps = 57/523 (10%)
Query: 84 WYQQPSNGDPLEDIRKSYPH--IIQDKCTLHFLTPGVNNSGSYICRPKMIKSPYDVACCV 141
WY + D E I P I ++K L F +N++G+Y C + + C
Sbjct: 70 WYWTRQDRDLEEPINFRLPENRISKEKDVLWFRPTLLNDTGNYTCMLR------NTTYCS 123
Query: 142 KMILEVKPQTNASCEYSAS----HKQDLLLGSTGSISCPSLSCQSDAQ-SPAVTWYKNGK 196
K+ ++ SC S HK + G I+CP++ + P +TWY
Sbjct: 124 KVAFPLEVVQKDSCFNSPMKLPVHKLYIEYGIQ-RITCPNVDGYFPSSVKPTITWYMG-- 180
Query: 197 LLSVERSNRIVVDEV-------YDYHQGTYVCDYTQSDTVSSWTVRAVVQVRTIVGDTKL 249
++ N ++ + + + G Y C T + ++ + + V+ +
Sbjct: 181 CYKIQNFNNVIPEGMNLSFLIALISNNGNYTCVVTYPENGRTFHLTRTLTVKVVGSPKNA 240
Query: 250 KPDILDPVEDTL--EVELGKPLTISCKARFGFERVFNPVIKWYI---KDSDLEWEVSVPE 304
P ++ D + E E G+ L I C F F + W I K D+ +V++ E
Sbjct: 241 VPPVIHSPNDHVVYEKEPGEELLIPCTVYFSFLMDSRNEVWWTIDGKKPDDITIDVTINE 300
Query: 305 AKSIKSTLKDEIIERNIILEKVTQRDLRRKFVCFVQNSIGNTTQSVQLKEK----RGVVL 360
+ S T +DE + + ++KVT DL+R +VC +++ G ++ ++K+K R V
Sbjct: 301 SISHSRT-EDETRTQILSIKKVTSEDLKRSYVCHARSAKGEVAKAAKVKQKVPAPRYTVE 359
Query: 361 LYILLGTIGTLVAVLAASALLYRHWIEIVLLYRTYQSKDQTLGDKKDFDAFVSYAKWSSF 420
L G LV +L +Y W+E+VL YR + D+T+ D K++D +VSYA+
Sbjct: 360 LACGFGATVLLVVILIVVYHVY--WLEMVLFYRAHFGTDETILDGKEYDIYVSYAR---- 413
Query: 421 PSEATSSLSEEHLALSLFPDVLENKYGYSLCLLERDVAPGGVYAEDIVSIIKRSRRGIFI 480
+ EE L VLEN++GY LC+ +RD PGG+ ++ +S I++SRR + +
Sbjct: 414 ------NAEEEEFVLLTLRGVLENEFGYKLCIFDRDSLPGGIVTDETLSFIQKSRRLLVV 467
Query: 481 LSPNYV--NGPSIFELQAAVNLALDDQTLKLILIKFCYFQEPESLPHLVKKALRVLPTVT 538
LSPNYV ++ EL+A + + +IL++ Y E+ +K+A VL +
Sbjct: 468 LSPNYVLQGTQALLELKAGLENMASRGNINVILVQ--YKAVKETKVKELKRAKTVLTVIK 525
Query: 539 WRGLKSVPPNSRFWAKMRYHMPVKNS--------QGFTWNQLR 573
W+G KS P RFW +++ MPVK S QG +++ L+
Sbjct: 526 WKGEKSKYPQGRFWKQLQVAMPVKKSPRRSSSDEQGLSYSSLK 568
>gi|4504655 interleukin 18 receptor 1 precursor [Homo sapiens]
Length = 541
Score = 170 bits (431), Expect = 3e-42
Identities = 142/505 (28%), Positives = 235/505 (46%), Gaps = 63/505 (12%)
Query: 84 WYQQPSNGDPLEDIRKSYPHIIQDKCTLHFLTPGVNNSGSYICRPKMIKSPYDVACCVKM 143
WY+ + + +E +S I C L F +N++GSY + K K
Sbjct: 56 WYKSSGSQEHVELNPRSSSRIALHDCVLEFWPVELNDTGSYFFQMKNYTQ--------KW 107
Query: 144 ILEVKPQTNASCEYSASHKQDLL-LGSTGSISCPSLSCQSDAQSPAVTWYKNGKLLSVER 202
L V + SC ++ + I+C + Q+ S ++ YKN K L +E
Sbjct: 108 KLNVIRRNKHSCFTERQVTSKIVEVKKFFQITCENSYYQTLVNSTSL--YKNCKKLLLEN 165
Query: 203 SNRIVVDEVYDYH-QGTYVCDYTQSDTVSSWTVRAVVQVRTIVGDTKLKPDILDPVEDTL 261
+ + + ++ QG Y C + + + + + + + P +L P + +
Sbjct: 166 NKNPTIKKNAEFEDQGYYSCVHFLHHNGKLFNITKTFNITIVEDRSNIVPVLLGPKLNHV 225
Query: 262 EVELGKPLTISCKARFGFERVFNPVIKWYIKDS---------DLEWEVSVPEAKSIKSTL 312
VELGK + ++C A E VI W + + E + PE K S +
Sbjct: 226 AVELGKNVRLNCSALLNEE----DVIYWMFGEENGSDPNIHEEKEMRIMTPEGKWHASKV 281
Query: 313 KDEIIERNIILEKVTQRDLRRKFVCFVQNSIGNTTQSVQLKEK------------RGVVL 360
+ +E + + +L + C V ++ G T+S L K RG+++
Sbjct: 282 --------LRIENIGESNLNVLYNCTVASTGGTDTKSFILVRKADMADIPGHVFTRGMII 333
Query: 361 LYILLGTIGTLVAVLAASALLYRHWIEIVLLYRTYQSKDQTLGDKKDFDAFVSYAKWSSF 420
++L + LV V ++YR +++VL YR +D+TL D K +DAFVSY K
Sbjct: 334 AVLILVAVVCLVTV----CVIYR--VDLVLFYRHLTRRDETLTDGKTYDAFVSYLK---- 383
Query: 421 PSEATSSLSEEH-LALSLFPDVLENKYGYSLCLLERDVAPGGVYAEDIVSIIKRSRRGIF 479
E EEH A+ + P VLE +GY LC+ ERDV PGG ++I S+I++SRR I
Sbjct: 384 --ECRPENGEEHTFAVEILPRVLEKHFGYKLCIFERDVVPGGAVVDEIHSLIEKSRRLII 441
Query: 480 ILSPNYVNGPSIFELQAAVNLALDDQTLKLILIKFCYFQEPESLPHLVK--KALRVLPTV 537
+LS +Y++ +EL++ ++ AL ++ +K+ILI+F + LP +K K+ RVL
Sbjct: 442 VLSKSYMSNEVRYELESGLHEALVERKIKIILIEFTPVTDFTFLPQSLKLLKSHRVL--- 498
Query: 538 TWRGLKSVPPNSRFWAKMRYHMPVK 562
W+ KS+ NSRFW + Y MP K
Sbjct: 499 KWKADKSLSYNSRFWKNLLYLMPAK 523
>gi|27894324 interleukin 1 receptor-like 1 isoform 1 precursor [Homo
sapiens]
Length = 556
Score = 145 bits (365), Expect = 1e-34
Identities = 131/511 (25%), Positives = 229/511 (44%), Gaps = 50/511 (9%)
Query: 82 VQWYQQPSNGD-PLEDIRKSYPHIIQDKCTLHFLTPGVNNSGSYICRPKMIKSPYDVACC 140
V WY +N P ++ + + L FL V +SG Y C +++SP
Sbjct: 46 VDWYYSQTNKSIPTQERNR----VFASGQLLKFLPAAVADSGIYTC---IVRSPTFNRTG 98
Query: 141 VKMILEVKPQTNASCEYSASHKQDLLLGSTGS-------ISCPSLSCQSDAQSPAVTWYK 193
+ K Q++ + D L+ ST S I CP++ + + + W+K
Sbjct: 99 YANVTIYKKQSDCNVP-------DYLMYSTVSGSEKNSKIYCPTIDLYN--WTAPLEWFK 149
Query: 194 NGKLLSVER----SNRIVVDEVYDYHQGTYVCDYTQSDTVSSWTVRAVVQVRTIVGDT-- 247
N + L R + +V+D V G Y C + ++ ++++V A T+ +
Sbjct: 150 NCQALQGSRYRAHKSFLVIDNVMTEDAGDYTCKFIHNENGANYSVTATRSF-TVKDEQGF 208
Query: 248 KLKPDILDPVEDTL-EVELGKPLTISCKARFGFERVFNPVIKWYIKDSDLE--WEVSVPE 304
L P I P ++ + EVE+GK ++C A FG F + W + + + E + +
Sbjct: 209 SLFPVIGAPAQNEIKEVEIGKNANLTCSACFGKGTQFLAAVLWQLNGTKITDFGEPRIQQ 268
Query: 305 AKSIKSTLKDEIIERNIILE--KVTQRDLRRKFVCFVQNSIGNTTQSVQLKEKRGVV--L 360
+ + + + +++L V + DL ++ C N G +V+L K +
Sbjct: 269 EEGQNQSFSNGLACLDMVLRIADVKEEDLLLQYDCLALNLHGLRRHTVRLSRKNPIDHHS 328
Query: 361 LYILLGTIGTLVAVLAASALLYR-HWIEIVLLYRTYQSKDQTLGDKKDFDAFVSYAKWSS 419
+Y ++ + ++ ++ + WIE LL+R +T D K +DA+V Y + +
Sbjct: 329 IYCIIAVCSVFLMLINVLVIILKMFWIEATLLWRDIAKPYKTRNDGKLYDAYVVYPR--N 386
Query: 420 FPSEATSSLSEEHLALSLFPDVLENKYGYSLCLLERDVAPGGVYAEDIVSIIKRSRRGIF 479
+ S + EH + PDVLENK GY+LC+ RD+ PG + + I++SRR IF
Sbjct: 387 YKSSTDGASRVEHFVHQILPDVLENKCGYTLCIYGRDMLPGEDVVTAVETNIRKSRRHIF 446
Query: 480 ILSPNYV-NGPSIFELQAAVNLALDDQTLKLILIKFCYFQE-----PESLPHLVKKALRV 533
IL+P N +E + A++ AL K+ILI+ E E+L ++ ++V
Sbjct: 447 ILTPQITHNKEFAYEQEVALHCALIQNDAKVILIEMEALSELDMLQAEALQDSLQHLMKV 506
Query: 534 LPTVTWRG---LKSVPPNSRFWAKMRYHMPV 561
T+ WR NS+FW +RY MPV
Sbjct: 507 QGTIKWREDHIANKRSLNSKFWKHVRYQMPV 537
>gi|4504659 interleukin 1 receptor, type I precursor [Homo sapiens]
Length = 569
Score = 136 bits (342), Expect = 6e-32
Identities = 130/515 (25%), Positives = 226/515 (43%), Gaps = 42/515 (8%)
Query: 82 VQWYQQPSNGDPLEDIRKSYPHIIQDKCTLHFLTPGVNNSGSYICRPKMIKSPYDVACCV 141
+ WY+ S P+ + S H Q K L F+ V +SG Y C + S Y C+
Sbjct: 55 ITWYKDDSK-TPVSTEQASRIH--QHKEKLWFVPAKVEDSGHYYCVVR--NSSY----CL 105
Query: 142 KMILEVK---PQTNASCEYSASHKQDLLLGSTGSISCPSLSC--QSDAQSPAVTWYKNGK 196
++ + K + N A KQ L + G + CP + + + P + WYK+ K
Sbjct: 106 RIKISAKFVENEPNLCYNAQAIFKQKLPVAGDGGLVCPYMEFFKNENNELPKLQWYKDCK 165
Query: 197 LLSVER------SNRIVVDEVYDYHQGTYVCDYTQSDTVSSWTVRAVVQVRTIVGDTKLK 250
L ++ +R++V V + H+G Y C + + + + V++ T+ + +
Sbjct: 166 PLLLDNIHFSGVKDRLIVMNVAEKHRGNYTCHASYTYLGKQYPITRVIEFITLEENKPTR 225
Query: 251 PDILDPVEDTLEVELGKPLTISCKARFGFERVFNPVIKWYIKDSDLEWEVSVPEAKSIK- 309
P I+ P +T+EV+LG + + C + KW D + V + S++
Sbjct: 226 PVIVSPANETMEVDLGSQIQLICNVTGQLSDI--AYWKWNGSVIDEDDPVLGEDYYSVEN 283
Query: 310 -STLKDEIIERNIILEKVTQRDLRRKFVCFVQNSIGNTTQSVQLKEKRGVVLLYILLGTI 368
+ + + + + ++ R + F CF +N+ G +QL + ++G
Sbjct: 284 PANKRRSTLITVLNISEIESRFYKHPFTCFAKNTHGIDAAYIQLIYPVTNFQKH-MIGIC 342
Query: 369 GTLVAVLAASALLYRHW-IEIVLLYR--TYQSKDQTLGDKKDFDAFVSYAKWSSFPSEAT 425
TL ++ S +Y+ + I+IVL YR Y D K +DA++ Y K S +
Sbjct: 343 VTLTVIIVCSVFIYKIFKIDIVLWYRDSCYDFLPIKASDGKTYDAYILYPKTVGEGSTSD 402
Query: 426 SSLSEEHLALSLFPDVLENKYGYSLCLLERDVAPGGVYAEDIVSIIKRSRRGIFIL---- 481
+ + P+VLE + GY L + RD G E I +K+SRR I IL
Sbjct: 403 CDI----FVFKVLPEVLEKQCGYKLFIYGRDDYVGEDIVEVINENVKKSRRLIIILVRET 458
Query: 482 -SPNYVNGPSIFELQAAVNLALDDQTLKLILIKFCYFQEPESLPHLVKKALRVLPTVTWR 540
+++ G S E Q A+ AL +K++L++ Q+ E +P +K + + W
Sbjct: 459 SGFSWLGGSS--EEQIAMYNALVQDGIKVVLLELEKIQDYEKMPESIKFIKQKHGAIRWS 516
Query: 541 GLKSVPPNS---RFWAKMRYHMPVKNSQGFTWNQL 572
G + P S RFW +RYHMPV+ + +QL
Sbjct: 517 GDFTQGPQSAKTRFWKNVRYHMPVQRRSPSSKHQL 551
>gi|28416902 interleukin 1 receptor-like 2 precursor [Homo sapiens]
Length = 575
Score = 119 bits (298), Expect = 8e-27
Identities = 141/525 (26%), Positives = 228/525 (43%), Gaps = 44/525 (8%)
Query: 72 PFMGSNDLSDVQWYQQPSNGDPLEDIRKSYPHIIQDKCTLHFLTPGVNNSGSYICRPKMI 131
P + S ++S V WY+ S P+ I +S H QD+ + FL +SG Y C K
Sbjct: 45 PPITSGEVS-VTWYKNSSK-IPVSKIIQSRIH--QDETWILFLPMEWGDSGVYQCVIKGR 100
Query: 132 KSPYDVACCVKMILEVKPQTNASC----EYSASHKQDLLLGSTGSISCPSLSCQSDAQSP 187
S + + V + + K + S S +KQ L LG S++C +S P
Sbjct: 101 DSCHRIH--VNLTVFEKHWCDTSIGGLPNLSDEYKQILHLGKDDSLTCHLHFPKSCVLGP 158
Query: 188 AVTWYKNGKLLSVER----SNRIVVDEVYDYHQGTYVCDYTQSDTVSSWTVR--AVVQVR 241
+ WYK+ + ER R++V V +G Y C + + + V V +
Sbjct: 159 -IKWYKDCNEIKGERFTVLETRLLVSNVSAEDRGNYACQAILTHSGKQYEVLNGITVSIT 217
Query: 242 TIVGDTKLKPDILDPVEDTLEVELGKPLTISCKARFGFE-------RVFNPVIKWYIKDS 294
G P I+ P ++EV+LG L + C + RV N ++ Y +S
Sbjct: 218 ERAGYGGSVPKIIYPKNHSIEVQLGTTLIVDCNVTDTKDNTNLRCWRVNNTLVDDYYDES 277
Query: 295 DLEWEVSVPEAKSIKSTLKDEIIERNIILEKVTQRDLRRKFVCFVQNSIGNTTQSVQLKE 354
E ++ S + + NI +V D F+C G +T + L+
Sbjct: 278 KRIRE----GVETHVSFREHNLYTVNITFLEVKMEDYGLPFMCHA----GVSTAYIILQL 329
Query: 355 KRGVVLLYILLGTIGTLVAVLAASALLYRHW-IEIVLLYRTYQSKDQTLGDKKDFDAFVS 413
Y++ G I LVAV + +Y + I+IVL YR+ +T+ D K +DA+V
Sbjct: 330 PAPDFRAYLIGGLIA-LVAVAVSVVYIYNIFKIDIVLWYRSAFHSTETIVDGKLYDAYVL 388
Query: 414 YAKWSSFPSEATSSLSEEHLALSLFPDVLENKYGYSLCLLERDVAPGGVYAEDIVSIIKR 473
Y K P + + + + L L++ P+VLE + GY L + RD PG A I +K
Sbjct: 389 YPK----PHKESQRHAVDALVLNILPEVLERQCGYKLFIFGRDEFPGQAVANVIDENVKL 444
Query: 474 SRRGIFILSPNYVNG---PSIFELQAAVNLALDDQTLKLILIKFCYFQEPESLPHLVKKA 530
RR I I+ P + ++ E Q AV AL +K+ILI+ ++ +P ++
Sbjct: 445 CRRLIVIVVPESLGFGLLKNLSEEQIAVYSALIQDGMKVILIELEKIEDYTVMPESIQYI 504
Query: 531 LRVLPTVTWRG---LKSVPPNSRFWAKMRYHMPVKNSQGFTWNQL 572
+ + W G +S ++FW +RYHMP + + F QL
Sbjct: 505 KQKHGAIRWHGDFTEQSQCMKTKFWKTVRYHMPPRRCRPFPPVQL 549
>gi|27894334 interleukin 1 receptor, type II precursor [Homo
sapiens]
Length = 398
Score = 78.2 bits (191), Expect = 2e-14
Identities = 70/270 (25%), Positives = 113/270 (41%), Gaps = 21/270 (7%)
Query: 120 NSGSYICRPKMIKSPYDVACCVKMILEVKPQTNASCEYS-ASHKQDLLLGSTGSISCPSL 178
+SG+Y+C + + + C KM +E++ N S+ Q L L ++G + CP L
Sbjct: 102 DSGTYVCTTR------NASYCDKMSIELRVFENTDAFLPFISYPQILTLSTSGVLVCPDL 155
Query: 179 S-CQSDAQSPAVTWYK--------NGKLLSVERSNRIVVDEVYDYHQGTYVCDYTQSDTV 229
S D + WYK N K LSV + ++V +V G Y C T +
Sbjct: 156 SEFTRDKTDVKIQWYKDSLLLDKDNEKFLSVRGTTHLLVHDVALEDAGYYRCVLTFAHEG 215
Query: 230 SSWTVRAVVQVRTIVGDTKLKPDILDPVEDTLEVELGKPLTISCKARFGFERVFNPVIKW 289
+ + +++R + P I+ P++ T+ LG LTI CK G ++ W
Sbjct: 216 QQYNITRSIELRIKKKKEETIPVIISPLK-TISASLGSRLTIPCKVFLGTGTPLTTMLWW 274
Query: 290 YIKDSDLEWEVS---VPEA-KSIKSTLKDEIIERNIILEKVTQRDLRRKFVCFVQNSIGN 345
D+ +E V E + S + IE +I + VT+ DL F C V N++
Sbjct: 275 TANDTHIESAYPGGRVTEGPRQEYSENNENYIEVPLIFDPVTREDLHMDFKCVVHNTLSF 334
Query: 346 TTQSVQLKEKRGVVLLYILLGTIGTLVAVL 375
T +KE I+L + VL
Sbjct: 335 QTLRTTVKEASSTFSWGIVLAPLSLAFLVL 364
>gi|4758598 interleukin 1 receptor, type II precursor [Homo sapiens]
Length = 398
Score = 78.2 bits (191), Expect = 2e-14
Identities = 70/270 (25%), Positives = 113/270 (41%), Gaps = 21/270 (7%)
Query: 120 NSGSYICRPKMIKSPYDVACCVKMILEVKPQTNASCEYS-ASHKQDLLLGSTGSISCPSL 178
+SG+Y+C + + + C KM +E++ N S+ Q L L ++G + CP L
Sbjct: 102 DSGTYVCTTR------NASYCDKMSIELRVFENTDAFLPFISYPQILTLSTSGVLVCPDL 155
Query: 179 S-CQSDAQSPAVTWYK--------NGKLLSVERSNRIVVDEVYDYHQGTYVCDYTQSDTV 229
S D + WYK N K LSV + ++V +V G Y C T +
Sbjct: 156 SEFTRDKTDVKIQWYKDSLLLDKDNEKFLSVRGTTHLLVHDVALEDAGYYRCVLTFAHEG 215
Query: 230 SSWTVRAVVQVRTIVGDTKLKPDILDPVEDTLEVELGKPLTISCKARFGFERVFNPVIKW 289
+ + +++R + P I+ P++ T+ LG LTI CK G ++ W
Sbjct: 216 QQYNITRSIELRIKKKKEETIPVIISPLK-TISASLGSRLTIPCKVFLGTGTPLTTMLWW 274
Query: 290 YIKDSDLEWEVS---VPEA-KSIKSTLKDEIIERNIILEKVTQRDLRRKFVCFVQNSIGN 345
D+ +E V E + S + IE +I + VT+ DL F C V N++
Sbjct: 275 TANDTHIESAYPGGRVTEGPRQEYSENNENYIEVPLIFDPVTREDLHMDFKCVVHNTLSF 334
Query: 346 TTQSVQLKEKRGVVLLYILLGTIGTLVAVL 375
T +KE I+L + VL
Sbjct: 335 QTLRTTVKEASSTFSWGIVLAPLSLAFLVL 364
>gi|205277451 single Ig IL-1R-related molecule [Homo sapiens]
Length = 410
Score = 68.2 bits (165), Expect = 2e-11
Identities = 80/319 (25%), Positives = 146/319 (45%), Gaps = 24/319 (7%)
Query: 251 PDILDPVED-TLEVELGKPLTISCKARF-GFERVFNPVIKWYIKDS---DLEWEVSVPEA 305
PD L P ED L LG + ++C A P ++W +KD + S+ E
Sbjct: 9 PDFLSPSEDQVLRPALGSSVALNCTAWVVSGPHCSLPSVQW-LKDGLPLGIGGHYSLHEY 67
Query: 306 KSIKSTLKDEIIERNIILEKVTQRDLRRKFVCFVQNSIGNTTQSVQLKEKRGVVLLYILL 365
+K+ L E++ +++ VT ++ F C +QN + S L+ + +L
Sbjct: 68 SWVKANLS-EVLVSSVLGVNVTSTEVYGAFTCSIQNI---SFSSFTLQRAGPTSHVAAVL 123
Query: 366 GTIGTLVAVLAASALLYRHWIEIVLLYRTYQSKDQTLGDKKDFDAFVSYAKWSSFPSEAT 425
++ L+A+L A+ L + + ++L Y+ + + + D K +DA+VSY S P +
Sbjct: 124 ASLLVLLALLLAALLYVKCRLNVLLWYQDAYGEVE-INDGKLYDAYVSY---SDCPED-- 177
Query: 426 SSLSEEHLALSLFPDVLENKYGYSLCLLERDVAPGGVYAEDIVSIIKRSRRGIFILSPNY 485
+ + L P LE + GY L L +RD+ P + D++ + R RR I +LS +
Sbjct: 178 ----RKFVNFILKPQ-LERRRGYKLFLDDRDLLPRAEPSADLLVNLSRCRRLIVVLSDAF 232
Query: 486 VNGPSIFELQAAVNLALDDQTLKLILIKFCYFQEPESLP--HLVKKALRVLPTVTWRGLK 543
++ L + T + I I F + + P L+++ ++ + WR
Sbjct: 233 LSRAWCSHSFREGLCRLLELTRRPIFITFEGQRRDPAHPALRLLRQHRHLVTLLLWRP-G 291
Query: 544 SVPPNSRFWAKMRYHMPVK 562
SV P+S FW +++ +P K
Sbjct: 292 SVTPSSDFWKEVQLALPRK 310
>gi|205277449 single Ig IL-1R-related molecule [Homo sapiens]
Length = 410
Score = 68.2 bits (165), Expect = 2e-11
Identities = 80/319 (25%), Positives = 146/319 (45%), Gaps = 24/319 (7%)
Query: 251 PDILDPVED-TLEVELGKPLTISCKARF-GFERVFNPVIKWYIKDS---DLEWEVSVPEA 305
PD L P ED L LG + ++C A P ++W +KD + S+ E
Sbjct: 9 PDFLSPSEDQVLRPALGSSVALNCTAWVVSGPHCSLPSVQW-LKDGLPLGIGGHYSLHEY 67
Query: 306 KSIKSTLKDEIIERNIILEKVTQRDLRRKFVCFVQNSIGNTTQSVQLKEKRGVVLLYILL 365
+K+ L E++ +++ VT ++ F C +QN + S L+ + +L
Sbjct: 68 SWVKANLS-EVLVSSVLGVNVTSTEVYGAFTCSIQNI---SFSSFTLQRAGPTSHVAAVL 123
Query: 366 GTIGTLVAVLAASALLYRHWIEIVLLYRTYQSKDQTLGDKKDFDAFVSYAKWSSFPSEAT 425
++ L+A+L A+ L + + ++L Y+ + + + D K +DA+VSY S P +
Sbjct: 124 ASLLVLLALLLAALLYVKCRLNVLLWYQDAYGEVE-INDGKLYDAYVSY---SDCPED-- 177
Query: 426 SSLSEEHLALSLFPDVLENKYGYSLCLLERDVAPGGVYAEDIVSIIKRSRRGIFILSPNY 485
+ + L P LE + GY L L +RD+ P + D++ + R RR I +LS +
Sbjct: 178 ----RKFVNFILKPQ-LERRRGYKLFLDDRDLLPRAEPSADLLVNLSRCRRLIVVLSDAF 232
Query: 486 VNGPSIFELQAAVNLALDDQTLKLILIKFCYFQEPESLP--HLVKKALRVLPTVTWRGLK 543
++ L + T + I I F + + P L+++ ++ + WR
Sbjct: 233 LSRAWCSHSFREGLCRLLELTRRPIFITFEGQRRDPAHPALRLLRQHRHLVTLLLWRP-G 291
Query: 544 SVPPNSRFWAKMRYHMPVK 562
SV P+S FW +++ +P K
Sbjct: 292 SVTPSSDFWKEVQLALPRK 310
>gi|205277445 single Ig IL-1R-related molecule [Homo sapiens]
Length = 410
Score = 68.2 bits (165), Expect = 2e-11
Identities = 80/319 (25%), Positives = 146/319 (45%), Gaps = 24/319 (7%)
Query: 251 PDILDPVED-TLEVELGKPLTISCKARF-GFERVFNPVIKWYIKDS---DLEWEVSVPEA 305
PD L P ED L LG + ++C A P ++W +KD + S+ E
Sbjct: 9 PDFLSPSEDQVLRPALGSSVALNCTAWVVSGPHCSLPSVQW-LKDGLPLGIGGHYSLHEY 67
Query: 306 KSIKSTLKDEIIERNIILEKVTQRDLRRKFVCFVQNSIGNTTQSVQLKEKRGVVLLYILL 365
+K+ L E++ +++ VT ++ F C +QN + S L+ + +L
Sbjct: 68 SWVKANLS-EVLVSSVLGVNVTSTEVYGAFTCSIQNI---SFSSFTLQRAGPTSHVAAVL 123
Query: 366 GTIGTLVAVLAASALLYRHWIEIVLLYRTYQSKDQTLGDKKDFDAFVSYAKWSSFPSEAT 425
++ L+A+L A+ L + + ++L Y+ + + + D K +DA+VSY S P +
Sbjct: 124 ASLLVLLALLLAALLYVKCRLNVLLWYQDAYGEVE-INDGKLYDAYVSY---SDCPED-- 177
Query: 426 SSLSEEHLALSLFPDVLENKYGYSLCLLERDVAPGGVYAEDIVSIIKRSRRGIFILSPNY 485
+ + L P LE + GY L L +RD+ P + D++ + R RR I +LS +
Sbjct: 178 ----RKFVNFILKPQ-LERRRGYKLFLDDRDLLPRAEPSADLLVNLSRCRRLIVVLSDAF 232
Query: 486 VNGPSIFELQAAVNLALDDQTLKLILIKFCYFQEPESLP--HLVKKALRVLPTVTWRGLK 543
++ L + T + I I F + + P L+++ ++ + WR
Sbjct: 233 LSRAWCSHSFREGLCRLLELTRRPIFITFEGQRRDPAHPALRLLRQHRHLVTLLLWRP-G 291
Query: 544 SVPPNSRFWAKMRYHMPVK 562
SV P+S FW +++ +P K
Sbjct: 292 SVTPSSDFWKEVQLALPRK 310
>gi|19882209 interleukin 1 receptor accessory protein isoform 2
[Homo sapiens]
Length = 356
Score = 67.8 bits (164), Expect = 3e-11
Identities = 66/291 (22%), Positives = 123/291 (42%), Gaps = 29/291 (9%)
Query: 84 WYQQPSNGDPLEDIRKSYPH--IIQDKCTLHFLTPGVNNSGSYICRPKMIKSPYDVACCV 141
WY + D E I P I ++K L F +N++G+Y C + + C
Sbjct: 70 WYWTRQDRDLEEPINFRLPENRISKEKDVLWFRPTLLNDTGNYTCMLR------NTTYCS 123
Query: 142 KMILEVKPQTNASCEYSAS----HKQDLLLGSTGSISCPSLSCQSDAQ-SPAVTWYKNGK 196
K+ ++ SC S HK + G I+CP++ + P +TWY
Sbjct: 124 KVAFPLEVVQKDSCFNSPMKLPVHKLYIEYGIQ-RITCPNVDGYFPSSVKPTITWYMG-- 180
Query: 197 LLSVERSNRIVVDEV-------YDYHQGTYVCDYTQSDTVSSWTVRAVVQVRTIVGDTKL 249
++ N ++ + + + G Y C T + ++ + + V+ +
Sbjct: 181 CYKIQNFNNVIPEGMNLSFLIALISNNGNYTCVVTYPENGRTFHLTRTLTVKVVGSPKNA 240
Query: 250 KPDILDPVEDTL--EVELGKPLTISCKARFGFERVFNPVIKWYI---KDSDLEWEVSVPE 304
P ++ D + E E G+ L I C F F + W I K D+ +V++ E
Sbjct: 241 VPPVIHSPNDHVVYEKEPGEELLIPCTVYFSFLMDSRNEVWWTIDGKKPDDITIDVTINE 300
Query: 305 AKSIKSTLKDEIIERNIILEKVTQRDLRRKFVCFVQNSIGNTTQSVQLKEK 355
+ S T +DE + + ++KVT DL+R +VC +++ G ++ ++K+K
Sbjct: 301 SISHSRT-EDETRTQILSIKKVTSEDLKRSYVCHARSAKGEVAKAAKVKQK 350
>gi|27894328 interleukin 1 receptor-like 1 isoform 2 precursor [Homo
sapiens]
Length = 328
Score = 53.5 bits (127), Expect = 5e-07
Identities = 65/293 (22%), Positives = 121/293 (41%), Gaps = 36/293 (12%)
Query: 82 VQWYQQPSNGD-PLEDIRKSYPHIIQDKCTLHFLTPGVNNSGSYICRPKMIKSPYDVACC 140
V WY +N P ++ + + L FL V +SG Y C +++SP
Sbjct: 46 VDWYYSQTNKSIPTQERNR----VFASGQLLKFLPAAVADSGIYTC---IVRSPTFNRTG 98
Query: 141 VKMILEVKPQTNASCEYSASHKQDLLLGSTGS-------ISCPSLSCQSDAQSPAVTWYK 193
+ K Q++ + D L+ ST S I CP++ + + + W+K
Sbjct: 99 YANVTIYKKQSDCNVP-------DYLMYSTVSGSEKNSKIYCPTIDLYN--WTAPLEWFK 149
Query: 194 NGKLLSVER----SNRIVVDEVYDYHQGTYVCDYTQSDTVSSWTVRAVVQVRTIVGDT-- 247
N + L R + +V+D V G Y C + ++ ++++V A T+ +
Sbjct: 150 NCQALQGSRYRAHKSFLVIDNVMTEDAGDYTCKFIHNENGANYSVTATRSF-TVKDEQGF 208
Query: 248 KLKPDILDPVEDTL-EVELGKPLTISCKARFGFERVFNPVIKWYIKDSDL----EWEVSV 302
L P I P ++ + EVE+GK ++C A FG F + W + + + E +
Sbjct: 209 SLFPVIGAPAQNEIKEVEIGKNANLTCSACFGKGTQFLAAVLWQLNGTKITDFGEPRIQQ 268
Query: 303 PEAKSIKSTLKDEIIERNIILEKVTQRDLRRKFVCFVQNSIGNTTQSVQLKEK 355
E ++ + ++ + + V + DL ++ C N G +V+L K
Sbjct: 269 EEGQNQSFSNGLACLDMVLRIADVKEEDLLLQYDCLALNLHGLRRHTVRLSRK 321
>gi|41350337 toll-like receptor 1 [Homo sapiens]
Length = 786
Score = 53.1 bits (126), Expect = 7e-07
Identities = 47/159 (29%), Positives = 73/159 (45%), Gaps = 20/159 (12%)
Query: 408 FDAFVSYAKWSSFPSEATSSLSEEHLALSLFPDVLENKYGYSLCLLERDVAPGGVYAEDI 467
F AF+SY+ SF + L P++ K G +CL ER+ PG E+I
Sbjct: 637 FHAFISYSGHDSF-----------WVKNELLPNL--EKEGMQICLHERNFVPGKSIVENI 683
Query: 468 VSIIKRSRRGIFILSPNYVNGP-SIFELQAAVNLALDDQTLKLILI---KFCYFQEPESL 523
++ I++S + IF+LSPN+V +EL A + + + LILI + P S
Sbjct: 684 ITCIEKSYKSIFVLSPNFVQSEWCHYELYFAHHNLFHEGSNSLILILLEPIPQYSIPSSY 743
Query: 524 PHLVKKALRVLPTVTWRGLKSVPPNSRFWAKMRYHMPVK 562
H +K + + W KS FWA +R + +K
Sbjct: 744 -HKLKSLMARRTYLEWPKEKS--KRGLFWANLRAAINIK 779
>gi|20143971 toll-like receptor 6 [Homo sapiens]
Length = 796
Score = 50.8 bits (120), Expect = 3e-06
Identities = 58/214 (27%), Positives = 90/214 (42%), Gaps = 41/214 (19%)
Query: 363 ILLGTIGTLVAVLAASALLYRHWIEIVLLYRTYQSKDQT-----------LGDKKDFDAF 411
+L+ TIG + VLA + ++++ R QT L F AF
Sbjct: 586 LLIVTIGATMLVLAVTVTSLCIYLDLPWYLRMVCQWTQTRRRARNIPLEELQRNLQFHAF 645
Query: 412 VSYAKWSS--FPSEATSSLSEEHLALSLFPDVLENKYGYSLCLLERDVAPGGVYAEDIVS 469
+SY++ S SE L +E + +CL ER+ PG E+I++
Sbjct: 646 ISYSEHDSAWVKSELVPYLEKEDI---------------QICLHERNFVPGKSIVENIIN 690
Query: 470 IIKRSRRGIFILSPNYVNGP-SIFELQAAVNLALDDQTLKLILIKFCYFQEP---ESLP- 524
I++S + IF+LSPN+V +EL A + + + LILI EP S+P
Sbjct: 691 CIEKSYKSIFVLSPNFVQSEWCHYELYFAHHNLFHEGSNNLILI----LLEPIPQNSIPN 746
Query: 525 --HLVKKALRVLPTVTWRGLKSVPPNSRFWAKMR 556
H +K + + W KS FWA +R
Sbjct: 747 KYHKLKALMTQRTYLQWPKEKS--KRGLFWANIR 778
>gi|62865621 toll-like receptor 10 precursor [Homo sapiens]
Length = 811
Score = 44.7 bits (104), Expect = 2e-04
Identities = 28/95 (29%), Positives = 47/95 (49%), Gaps = 11/95 (11%)
Query: 392 YRTYQSKDQTLGDKKDFDAFVSYAKWSSFPSEATSSLSEEHLALSLFPDVLENKYGYSLC 451
+R ++ + L F AF+SY++ S + L P++ + +C
Sbjct: 618 HRVRKTTQEQLKRNVRFHAFISYSEHDSL-----------WVKNELIPNLEKEDGSILIC 666
Query: 452 LLERDVAPGGVYAEDIVSIIKRSRRGIFILSPNYV 486
L E PG +E+IVS I++S + IF+LSPN+V
Sbjct: 667 LYESYFDPGKSISENIVSFIEKSYKSIFVLSPNFV 701
>gi|62865618 toll-like receptor 10 precursor [Homo sapiens]
Length = 811
Score = 44.7 bits (104), Expect = 2e-04
Identities = 28/95 (29%), Positives = 47/95 (49%), Gaps = 11/95 (11%)
Query: 392 YRTYQSKDQTLGDKKDFDAFVSYAKWSSFPSEATSSLSEEHLALSLFPDVLENKYGYSLC 451
+R ++ + L F AF+SY++ S + L P++ + +C
Sbjct: 618 HRVRKTTQEQLKRNVRFHAFISYSEHDSL-----------WVKNELIPNLEKEDGSILIC 666
Query: 452 LLERDVAPGGVYAEDIVSIIKRSRRGIFILSPNYV 486
L E PG +E+IVS I++S + IF+LSPN+V
Sbjct: 667 LYESYFDPGKSISENIVSFIEKSYKSIFVLSPNFV 701
>gi|126517478 peroxidasin homolog-like [Homo sapiens]
Length = 1463
Score = 43.5 bits (101), Expect = 6e-04
Identities = 33/117 (28%), Positives = 50/117 (42%), Gaps = 19/117 (16%)
Query: 180 CQSDAQSPAV-TWYKNGKLLSVERSNRIV------VDEVYDYHQGTYVCDYTQSDTVSSW 232
C++D P V W K G L VE + ++ +D + QG Y C S V
Sbjct: 440 CEADGNPPPVIVWTKTGGQLPVEGQHTVLSSGTLRIDRAAQHDQGQYECQAVSSLGVKKV 499
Query: 233 TVRAVVQVRTIVGDTKLKPDILDPVEDTLEVELGKPLTISCKARFGFERVFNPVIKW 289
+V+ V+ + + T+L D VE+GK + ISC A + P+I W
Sbjct: 500 SVQLTVKPKALAVFTQLPQDT--------SVEVGKNINISCHA----QGEPQPIITW 544
>gi|19718734 toll-like receptor 2 [Homo sapiens]
Length = 784
Score = 43.1 bits (100), Expect = 7e-04
Identities = 37/134 (27%), Positives = 64/134 (47%), Gaps = 15/134 (11%)
Query: 408 FDAFVSYAKWSSFPSEATSSLSEEHLALSLFPDVLEN-KYGYSLCLLERDVAPGGVYAED 466
+DAFVSY++ ++ E +L LEN + LCL +RD PG ++
Sbjct: 641 YDAFVSYSERDAYWVE------------NLMVQELENFNPPFKLCLHKRDFIPGKWIIDN 688
Query: 467 IVSIIKRSRRGIFILSPNYVNGP-SIFELQAAVNLALDDQTLKLILIKFCYFQEPESLPH 525
I+ I++S + +F+LS N+V +EL + D+ ILI E +++P
Sbjct: 689 IIDSIEKSHKTVFVLSENFVKSEWCKYELDFSHFRLFDENNDAAILILLEPI-EKKAIPQ 747
Query: 526 LVKKALRVLPTVTW 539
K +++ T T+
Sbjct: 748 RFCKLRKIMNTKTY 761
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 43.1 bits (100), Expect = 7e-04
Identities = 38/139 (27%), Positives = 59/139 (42%), Gaps = 24/139 (17%)
Query: 163 QDLLLGSTGSISCPSLSCQSDA-QSPAVTWYKNGKLL-------SVERSNRIVVDEVYDY 214
QD +L G + LSC++DA P VTWYK+G+ L ++ R+ + E
Sbjct: 1848 QDAVLVRVGDKAV--LSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVS 1905
Query: 215 HQGTYVCDYTQSDTVSSWTVRAVVQVRTIVGDTKLKPDILDPVEDTLEVELGKPLTISCK 274
+G Y C + A VRT ++ P +P +T+ G PL ++C
Sbjct: 1906 DKGLYSCKVSNV---------AGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCD 1956
Query: 275 ARFGFERVFNPVIKWYIKD 293
V P + W +KD
Sbjct: 1957 V----SGVPAPTVTW-LKD 1970
Score = 32.0 bits (71), Expect = 1.7
Identities = 46/217 (21%), Positives = 84/217 (38%), Gaps = 31/217 (14%)
Query: 84 WYQQPSNGDPLEDIRKSYPHIIQDKCTLHFLTPGVNNSGSYICRPKMIKSPYDVACCVKM 143
W++ +G PL R HI D L L ++++G Y C + +
Sbjct: 1288 WFK---DGRPLA--RGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSV 1342
Query: 144 ILEVKPQTNASCEYSASHKQDLLLGSTGSISCPSLSCQSDAQSPAVTWYKNGKLLSVERS 203
+L P E SA + + + + S+ C +L+ S P +TW K+G R+
Sbjct: 1343 LLA--PTILGGAEDSADEEVTVTVNNPISLICEALAFPS----PNITWMKDGAPFEASRN 1396
Query: 204 NRIV-------VDEVYDYHQGTYVCDYTQ--SDTVSSWTVRAVVQVRTIVGDTKLKPDIL 254
+++ + G Y C T + V ++ V ++ + K D L
Sbjct: 1397 IQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNY------HVEVLIPPSISKDDPL 1450
Query: 255 DPV-EDTLEVELGKPLTISCKARFGFERVFNPVIKWY 290
V ++ ++ LT+ C++ V P I+WY
Sbjct: 1451 GEVGVKEVKTKVNSTLTLECES----WAVPPPTIRWY 1483
Score = 31.2 bits (69), Expect = 2.8
Identities = 46/188 (24%), Positives = 74/188 (39%), Gaps = 36/188 (19%)
Query: 177 SLSCQSDAQSPAV-TWYKNGKLL--------SVERSNRIVVDEVYDYHQGTYVCDYTQSD 227
+L CQS A P V +W+K+G+ L S +++ + VD + G Y C+
Sbjct: 898 ALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKA-LLQVDRADVWDAGHYTCEALNQA 956
Query: 228 TVSSWTVRAVVQVRTIVGDTKLKPDILDPVED--TLEVELGKPLTISCKARFGFERVFNP 285
S V V + P+ + TL V G P ++SC+ R V P
Sbjct: 957 GRSEKHYNLNVWVAPVF-----------PLRESHTLTVREGHPTSLSCECR----GVPFP 1001
Query: 286 VIKWYIKDSDLEWEVSVPEAKSIKSTLKDEIIERNIILEKVTQRDLRRKFVCFVQNSIGN 345
I W L E + + S + R + L + Q + C N +GN
Sbjct: 1002 KISWRKDGQPLPGEGAGLQHVSA--------VGRLLYLGQA-QLAQEGTYTCECSNVVGN 1052
Query: 346 TTQSVQLK 353
++Q +QL+
Sbjct: 1053 SSQDLQLE 1060
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 43.1 bits (100), Expect = 7e-04
Identities = 38/139 (27%), Positives = 59/139 (42%), Gaps = 24/139 (17%)
Query: 163 QDLLLGSTGSISCPSLSCQSDA-QSPAVTWYKNGKLL-------SVERSNRIVVDEVYDY 214
QD +L G + LSC++DA P VTWYK+G+ L ++ R+ + E
Sbjct: 3039 QDAVLVRVGDKAV--LSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVS 3096
Query: 215 HQGTYVCDYTQSDTVSSWTVRAVVQVRTIVGDTKLKPDILDPVEDTLEVELGKPLTISCK 274
+G Y C + A VRT ++ P +P +T+ G PL ++C
Sbjct: 3097 DKGLYSCKVSNV---------AGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCD 3147
Query: 275 ARFGFERVFNPVIKWYIKD 293
V P + W +KD
Sbjct: 3148 V----SGVPAPTVTW-LKD 3161
Score = 32.0 bits (71), Expect = 1.7
Identities = 46/217 (21%), Positives = 84/217 (38%), Gaps = 31/217 (14%)
Query: 84 WYQQPSNGDPLEDIRKSYPHIIQDKCTLHFLTPGVNNSGSYICRPKMIKSPYDVACCVKM 143
W++ +G PL R HI D L L ++++G Y C + +
Sbjct: 2479 WFK---DGRPLA--RGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSV 2533
Query: 144 ILEVKPQTNASCEYSASHKQDLLLGSTGSISCPSLSCQSDAQSPAVTWYKNGKLLSVERS 203
+L P E SA + + + + S+ C +L+ S P +TW K+G R+
Sbjct: 2534 LLA--PTILGGAEDSADEEVTVTVNNPISLICEALAFPS----PNITWMKDGAPFEASRN 2587
Query: 204 NRIV-------VDEVYDYHQGTYVCDYTQ--SDTVSSWTVRAVVQVRTIVGDTKLKPDIL 254
+++ + G Y C T + V ++ V ++ + K D L
Sbjct: 2588 IQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNY------HVEVLIPPSISKDDPL 2641
Query: 255 DPV-EDTLEVELGKPLTISCKARFGFERVFNPVIKWY 290
V ++ ++ LT+ C++ V P I+WY
Sbjct: 2642 GEVGVKEVKTKVNSTLTLECES----WAVPPPTIRWY 2674
Score = 31.2 bits (69), Expect = 2.8
Identities = 46/188 (24%), Positives = 74/188 (39%), Gaps = 36/188 (19%)
Query: 177 SLSCQSDAQSPAV-TWYKNGKLL--------SVERSNRIVVDEVYDYHQGTYVCDYTQSD 227
+L CQS A P V +W+K+G+ L S +++ + VD + G Y C+
Sbjct: 2089 ALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKA-LLQVDRADVWDAGHYTCEALNQA 2147
Query: 228 TVSSWTVRAVVQVRTIVGDTKLKPDILDPVED--TLEVELGKPLTISCKARFGFERVFNP 285
S V V + P+ + TL V G P ++SC+ R V P
Sbjct: 2148 GHSEKHYNLNVWVAPVF-----------PLRESHTLTVREGHPTSLSCECR----GVPFP 2192
Query: 286 VIKWYIKDSDLEWEVSVPEAKSIKSTLKDEIIERNIILEKVTQRDLRRKFVCFVQNSIGN 345
I W L E + + S + R + L + Q + C N +GN
Sbjct: 2193 KISWRKDGQPLPGEGAGLQHVSA--------VGRLLYLGQA-QLAQEGTYTCECSNVVGN 2243
Query: 346 TTQSVQLK 353
++Q +QL+
Sbjct: 2244 SSQDLQLE 2251
Score = 30.4 bits (67), Expect = 4.9
Identities = 51/263 (19%), Positives = 90/263 (34%), Gaps = 39/263 (14%)
Query: 107 DKCTLHFLTPGVNNSGSYICRPKMIKSPYDVACCVKMILEVKPQTNASCEYSASHKQDLL 166
D L F + + Y+C + + + + PQ +S +L
Sbjct: 843 DSGVLFFESVAPEDQAPYVCEARNVFGKVQAEARLIVTGHAPPQIASSAPTVR-----VL 897
Query: 167 LGSTGSISCPSLSCQSDAQSPAVTWYKNGKLL------SVERSNRIVVDEVYDYHQGTYV 220
G S+ C L+ + P W K+G+ L S+ + +D H G Y
Sbjct: 898 EGQPVSLPCIVLAGRP---LPERHWLKDGRPLPPGSRHSIRADGSLHLDRALQEHAGRYS 954
Query: 221 CDYTQSDTVSSWTVRAVVQVRTIVGDTKLKPDILDPVEDTLEVELGKPLTISCKARFGFE 280
C T + V VVQV P + P G P ++ C A
Sbjct: 955 CVATNTAGSQHRDVELVVQV----------PPRIHPTATHHITNEGVPASLPCVA----S 1000
Query: 281 RVFNPVIKWYIKDSDLEWEVSVPEAKSIKSTLKDEIIERNIILEKVTQRDLRRKFVCFVQ 340
V P I W A + + + E +++ + + +D +VC
Sbjct: 1001 GVPAPTITW----------TKETNALTSRGPHYNVSKEGTLLIAQPSAQD-AGAYVCTAT 1049
Query: 341 NSIGNTTQSVQLKEKRGVVLLYI 363
N++G ++Q ++L R + Y+
Sbjct: 1050 NTVGFSSQEMRLSVNRLALSKYV 1072
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 43.1 bits (100), Expect = 7e-04
Identities = 38/139 (27%), Positives = 59/139 (42%), Gaps = 24/139 (17%)
Query: 163 QDLLLGSTGSISCPSLSCQSDA-QSPAVTWYKNGKLL-------SVERSNRIVVDEVYDY 214
QD +L G + LSC++DA P VTWYK+G+ L ++ R+ + E
Sbjct: 1757 QDAVLVRVGDKAV--LSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVS 1814
Query: 215 HQGTYVCDYTQSDTVSSWTVRAVVQVRTIVGDTKLKPDILDPVEDTLEVELGKPLTISCK 274
+G Y C + A VRT ++ P +P +T+ G PL ++C
Sbjct: 1815 DKGLYSCKVSNV---------AGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCD 1865
Query: 275 ARFGFERVFNPVIKWYIKD 293
V P + W +KD
Sbjct: 1866 V----SGVPAPTVTW-LKD 1879
Score = 32.3 bits (72), Expect = 1.3
Identities = 43/216 (19%), Positives = 83/216 (38%), Gaps = 29/216 (13%)
Query: 84 WYQQPSNGDPLEDIRKSYPHIIQDKCTLHFLTPGVNNSGSYICRPKMIKSPYDVACCVKM 143
W++ +G PL R HI D L L ++++G Y C + +
Sbjct: 1197 WFK---DGRPLA--RGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSV 1251
Query: 144 ILEVKPQTNASCEYSASHKQDLLLGSTGSISCPSLSCQSDAQSPAVTWYKNGKLLSVERS 203
+L P E SA + + + + S+ C +L+ S P +TW K+G R+
Sbjct: 1252 LLA--PTILGGAEDSADEEVTVTVNNPISLICEALAFPS----PNITWMKDGAPFEASRN 1305
Query: 204 NRIV-------VDEVYDYHQGTYVCDYTQ--SDTVSSWTVRAVVQVRTIVGDTKLKPDIL 254
+++ + G Y C T + V ++ V ++ D + +
Sbjct: 1306 IQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLAEVGVK 1365
Query: 255 DPVEDTLEVELGKPLTISCKARFGFERVFNPVIKWY 290
+ ++ ++ LT+ C++ V P I+WY
Sbjct: 1366 E-----VKTKVNSTLTLECES----WAVPPPTIRWY 1392
Score = 30.4 bits (67), Expect = 4.9
Identities = 46/188 (24%), Positives = 73/188 (38%), Gaps = 36/188 (19%)
Query: 177 SLSCQSDAQSPAV-TWYKNGKLL--------SVERSNRIVVDEVYDYHQGTYVCDYTQSD 227
+L CQS A P V +W+K+G+ L S +++ + VD + G Y C+
Sbjct: 807 ALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKA-LLQVDRADVWDAGHYTCEALNQA 865
Query: 228 TVSSWTVRAVVQVRTIVGDTKLKPDILDPVED--TLEVELGKPLTISCKARFGFERVFNP 285
S V V + P+ + TL V G P +SC+ R V P
Sbjct: 866 GHSEKHYNLNVWVAPVF-----------PLRESHTLTVREGHPTRLSCECR----GVPFP 910
Query: 286 VIKWYIKDSDLEWEVSVPEAKSIKSTLKDEIIERNIILEKVTQRDLRRKFVCFVQNSIGN 345
I W L E + + S + R + L + Q + C N +GN
Sbjct: 911 KISWRKDGQPLPGEGAGLQHVSA--------VGRLLYLGQA-QLAQEGTYTCECSNVVGN 961
Query: 346 TTQSVQLK 353
++Q +QL+
Sbjct: 962 SSQDLQLE 969
>gi|148886752 immunoglobulin superfamily, member 9B [Homo sapiens]
Length = 1349
Score = 40.4 bits (93), Expect = 0.005
Identities = 71/318 (22%), Positives = 117/318 (36%), Gaps = 45/318 (14%)
Query: 35 STRSEEEFVLFCDLPEPQKSHFCHRNRLSPKQVPEHLPFMGSNDLSDVQWYQQPSNGDPL 94
+ R+ E VL CD+ P P V E F G +++ P + DP
Sbjct: 34 TARAGESVVLRCDVIHPVTGQ-------PPPYVVEWFKF-GVPIPIFIKFGYYPPHVDPE 85
Query: 95 EDIRKSYPHIIQDKCTLHFLTPGVNNSGSYICRPKMIKSPYDVACCVKMILEVKPQTNAS 154
R S + DK +L + G Y C+ M+ YD V NA
Sbjct: 86 YAGRAS----LHDKASLRLEQVRSEDQGWYECKVLMLDQQYDTFHNGSW---VHLTINAP 138
Query: 155 CEYSASHKQDLLLGSTGSISCPSLSCQSDAQ-SPAVTWYKNGKLLSVE-----RSNRIVV 208
++ + Q + GSI+ ++C + P VTW K G LL + V
Sbjct: 139 PTFTETPPQYIEAKEGGSIT---MTCTAFGNPKPIVTWLKEGTLLGASGKYQVSDGSLTV 195
Query: 209 DEVYDYHQGTYVCDYTQSDTVSSWTVRAVVQVRTIVGDTKLKPDILDPVEDTLEVELGKP 268
V +G Y C + T +VQ P I+ P E+ + V + +
Sbjct: 196 TSVSREDRGAYTCRAYSIQGEAVHTTHLLVQG---------PPFIVSPPEN-ITVNISQD 245
Query: 269 LTISCKARFGFERVFNPVIKWYIKDSDLEWEVSVPEAKSIKSTLKDEIIERNIILEKVTQ 328
++C+A N WY +D ++ ++ + I +I+ +I+ +V
Sbjct: 246 ALLTCRAE---AYPGNLTYTWYWQDENVYFQNDLKLRVRI-------LIDGTLIIFRVKP 295
Query: 329 RDLRRKFVCFVQNSIGNT 346
D K+ C NS+G +
Sbjct: 296 ED-SGKYTCVPSNSLGRS 312
>gi|20302168 toll-like receptor 8 [Homo sapiens]
Length = 1041
Score = 38.9 bits (89), Expect = 0.014
Identities = 40/160 (25%), Positives = 77/160 (48%), Gaps = 19/160 (11%)
Query: 359 VLLYILLGTIGTLVAVLAASALLYRHWIEIVLLYRTYQSKDQ---TLGDKKDF-DAFVSY 414
V+L+ I T+V + A + L+ +W ++ +Y +K + +L + F DA++SY
Sbjct: 829 VILFFFTFFITTMVMLAALAHHLF-YW-DVWFIYNVCLAKVKGYRSLSTSQTFYDAYISY 886
Query: 415 AKWSSFPSEATSSLSEEHLALSLFPDVLENKYGYSLCLLERDVAPGGVYAEDIVSIIKRS 474
+ ++ + HL S +VL LCL ERD PG ++++ I +S
Sbjct: 887 DTKDASVTDWVINELRYHLEESRDKNVL-------LCLEERDWDPGLAIIDNLMQSINQS 939
Query: 475 RRGIFILSPNYVNGPSIFELQAAVNLALD---DQTLKLIL 511
++ +F+L+ Y + + A LAL D+ + +I+
Sbjct: 940 KKTVFVLTKKYAKS---WNFKTAFYLALQRLMDENMDVII 976
>gi|4507531 toll-like receptor 3 [Homo sapiens]
Length = 904
Score = 38.1 bits (87), Expect = 0.023
Identities = 24/77 (31%), Positives = 39/77 (50%), Gaps = 2/77 (2%)
Query: 438 FPDVLENKYGYSLCLLERDVAPGGVYAEDIVSIIKRSRRGIFILSPNYVNGP--SIFELQ 495
F + + CL ERD G E IV+ IKRSR+ IF+++ + + P F++
Sbjct: 774 FSSMEKEDQSLKFCLEERDFEAGVFELEAIVNSIKRSRKIIFVITHHLLKDPLCKRFKVH 833
Query: 496 AAVNLALDDQTLKLILI 512
AV A++ +IL+
Sbjct: 834 HAVQQAIEQNLDSIILV 850
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 37.7 bits (86), Expect = 0.030
Identities = 63/262 (24%), Positives = 105/262 (40%), Gaps = 42/262 (16%)
Query: 102 PHI-IQDKCTLHFLTPGVNNSGSYICRPKMIKSPYDVACCVKMILEVKPQTNASCEYSAS 160
P+I ++ +LH + + G Y C + + V ++ V P +
Sbjct: 935 PYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSV--VVHVLP--------TIQ 984
Query: 161 HKQDLLLGSTGSISCPSLSCQSDAQ-SPAVTWYKNGKLLSVERSN-------RIVVDEVY 212
H Q +L ST +L C++ P+V W K G+L+S + + V
Sbjct: 985 HGQQIL--STIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPG 1042
Query: 213 DYHQGTYVCDYTQSDTVSSWTVRAVVQVRT-IVGDTK-LKPDILDPVEDTLEVELGKPLT 270
G YVC T + + V+ V VR + GD + L D PVE + V G+ +T
Sbjct: 1043 GEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQD--KPVE--ISVLAGEEVT 1098
Query: 271 ISCKARFGFERVFNPVIKWYIKDSDLEWEVSVPEAKSIKSTLKDEIIERNIILEKVTQRD 330
+ C+ + + P+I W K++ L S ++K I E T+
Sbjct: 1099 LPCEVK----SLPPPIITW-AKETQLISPFSPRHTFLPSGSMK--------ITE--TRTS 1143
Query: 331 LRRKFVCFVQNSIGNTTQSVQL 352
++C N GN TQ+V+L
Sbjct: 1144 DSGMYLCVATNIAGNVTQAVKL 1165
Score = 37.4 bits (85), Expect = 0.040
Identities = 27/104 (25%), Positives = 48/104 (46%), Gaps = 11/104 (10%)
Query: 177 SLSCQSDA-QSPAVTWYKNGKLLSVERSNRIVVDEVYDYHQGTYVCDYTQSDTVSSWTVR 235
SL C+S+A P +TWYKNG++++ I+ D Q ++ SDT + R
Sbjct: 3078 SLECESNAVPPPVITWYKNGRMITESTHVEILAD-----GQMLHIKKAEVSDT-GQYVCR 3131
Query: 236 AVVQV----RTIVGDTKLKPDILDPVEDTLEVELGKPLTISCKA 275
A+ + + + P I P + + + P+T++C A
Sbjct: 3132 AINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDA 3175
Score = 36.6 bits (83), Expect = 0.068
Identities = 35/183 (19%), Positives = 69/183 (37%), Gaps = 34/183 (18%)
Query: 178 LSCQSDAQ-SPAVTWYKNGKLLSVERSNRIV-------VDEVYDYHQGTYVCDYTQSDTV 229
L C++ SP +TW K G ++ N V + GTY+C
Sbjct: 4007 LPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGT 4066
Query: 230 SSWTVRAVVQVRTIVGDTKLKPDILDPVEDTLEVELGKPLTISCKARFGFERVFNPVIKW 289
+ ++ VQV P ++ P + + KP+T+SC+A + + P I W
Sbjct: 4067 ALGKIKLNVQV----------PPVISPHLKEYVIAVDKPITLSCEA----DGLPPPDITW 4112
Query: 290 YIKDSDLEWEVSVPEAKSIKSTLKDEIIERNIILEKVTQRDLRRKFVCFVQNSIGNTTQS 349
+ + ++I +++ ++ + Q + C N G+++ S
Sbjct: 4113 H------------KDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTS 4160
Query: 350 VQL 352
+L
Sbjct: 4161 TKL 4163
Score = 35.0 bits (79), Expect = 0.20
Identities = 48/220 (21%), Positives = 86/220 (39%), Gaps = 48/220 (21%)
Query: 77 NDLSDVQWYQQPSNGDPLEDIRKSYPHIIQDKCTLHFLTPGVNNSGSYICRPKMIKSPYD 136
N + ++ W++ +G PL++ HII L V ++G Y C
Sbjct: 2506 NPVPEITWHK---DGQPLQEDEAH--HIISGGRFLQITNVQVPHTGRYTC---------- 2550
Query: 137 VACCVKMILEVKPQTNASCEYSASHKQDLLLGSTGSISCP-----------SLSCQSDAQ 185
L P + S +S + + GS P SL C++ +
Sbjct: 2551 --------LASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSY 2602
Query: 186 SPA-VTWYKNGKLLSVERSNRIV-------VDEVYDYHQGTYVCDYTQ--SDTVSSWTVR 235
PA +TW+K+G L R+ RI+ + + + G Y C T + + + V+
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVK 2662
Query: 236 AVVQVRTIVGDTKLKPDILDPVEDTLEVELGKPLTISCKA 275
V + I+ L L P E +++++ LT+ C+A
Sbjct: 2663 --VYIPPIINKGDLWGPGLSPKE--VKIKVNNTLTLECEA 2698
Score = 33.5 bits (75), Expect = 0.57
Identities = 46/186 (24%), Positives = 68/186 (36%), Gaps = 35/186 (18%)
Query: 177 SLSCQSDA-QSPAVTWYKNGKLLSVER---------SNRIVVDEVYDYHQGTYVCDYTQS 226
+L+C++ P++ W KNG LL+V++ S +V+ TY C T
Sbjct: 3822 TLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNG 3881
Query: 227 DTVSSWTVRAVVQVRTIVGDTKLKPDILDPVEDTLEVELGKPLTISCKARFGFERVFNPV 286
TV VQV P I D D L V P I+C A V P
Sbjct: 3882 AGDDKRTVDLTVQV---------PPSIADEPTDFL-VTKHAPAVITCTA----SGVPFPS 3927
Query: 287 IKWYIKDSDLEWEVSVPEAKSIKSTLKDEIIERNIILEKVTQRDLRRKFVCFVQNSIGNT 346
I W L +P + I+ I TQ + ++ C +N+ G+
Sbjct: 3928 IHWTKNGIRL-----LPRGDGYR------ILSSGAIEILATQLNHAGRYTCVARNAAGSA 3976
Query: 347 TQSVQL 352
+ V L
Sbjct: 3977 HRHVTL 3982
Score = 31.6 bits (70), Expect = 2.2
Identities = 51/246 (20%), Positives = 89/246 (36%), Gaps = 45/246 (18%)
Query: 119 NNSGSYICRPKMIKSPYDVACCVKMILEVKPQTNASCEYSASHKQDLLLGSTGSISCPSL 178
++SG Y+C I +V VK+ + V P+ ++ + +G I C +
Sbjct: 1143 SDSGMYLCVATNIAG--NVTQAVKLNVHVPPKIQRGPKHLK-----VQVGQRVDIPCNA- 1194
Query: 179 SCQSDAQSPAVTWYKNGKLLSVERSNRI-------VVDEVYDYHQGTYVCDYTQSDTVSS 231
P +TW K G + V+ + + +D+ G Y C T
Sbjct: 1195 ---QGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTDE 1251
Query: 232 WTVRAVVQVRTIVGDTKLKPDILDPVEDTLEVEL-GKPLTISCKARFGFERVFNPVIKWY 290
+ VQ V D L+P P T + + + + C A+ P IKW
Sbjct: 1252 TEITLHVQEPPTVED--LEP----PYNTTFQERVANQRIEFPCPAK----GTPKPTIKWL 1301
Query: 291 IKDSDL---EWEVSVPEAKSIKSTLKDEIIERNIILEKVTQRDLRRKFVCFVQNSIGNTT 347
+L E +S+ E ++ +++ VT D +++C N G T
Sbjct: 1302 HNGRELTGREPGISILEDGTL------------LVIASVTPYD-NGEYICVAVNEAGTTE 1348
Query: 348 QSVQLK 353
+ LK
Sbjct: 1349 RKYNLK 1354
Score = 30.4 bits (67), Expect = 4.9
Identities = 35/173 (20%), Positives = 60/173 (34%), Gaps = 30/173 (17%)
Query: 187 PAVTWYKNGKLLSVE-------RSNRIVVDEVYDYHQGTYVCDYTQSDTVSSWTVRAVVQ 239
P + W K+G+L+ ++V+ + + G Y C + V
Sbjct: 1764 PTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVH 1823
Query: 240 VRTIVGDTKLKPDILDPVEDTLEVELGKPLTISCKARFGFERVFNPVIKWYIKDSDLEWE 299
V + + L + V KP+ + C A + NP I W D +
Sbjct: 1824 VPPTIKSSGLSERV---------VVKYKPVALQCIAN----GIPNPSITWLKDDQPVN-- 1868
Query: 300 VSVPEAKSIKSTLKDEIIERNIILEKVTQRDLRRKFVCFVQNSIGNTTQSVQL 352
+ + LK + R + + K D R + C N+ G T Q +QL
Sbjct: 1869 -------TAQGNLKIQSSGRVLQIAKTLLEDAGR-YTCVATNAAGETQQHIQL 1913
Score = 29.6 bits (65), Expect = 8.3
Identities = 41/220 (18%), Positives = 84/220 (38%), Gaps = 32/220 (14%)
Query: 81 DVQWYQQPSNGDPLEDIRKSYPHIIQDKCTLHFLTPGVNNSGSYICRPKMIKSPYDVACC 140
D+ W++ +G PL + ++ LH N+ G Y C + + A
Sbjct: 1484 DIHWFK---DGKPLF-LGDPNVELLDRGQVLHLKNARRNDKGRYQCT--VSNAAGKQAKD 1537
Query: 141 VKMILEVKPQTNASCEYSASHKQDLLLGSTGSISCPSLSCQSDAQSPAVTWYKNG----- 195
+K+ + + P + + +L+ S + C + PA+TWYK+G
Sbjct: 1538 IKLTIYIPPSIKGG---NVTTDISVLINSLIKLECETRGLPM----PAITWYKDGQPIMS 1590
Query: 196 --KLLSVERSNRIVVDEVYDYHQGTYVCDYTQSDTVSSWTVRAVVQVRTIVGDTKLKPDI 253
+ L +++ + + TY C + + V V ++ + ++
Sbjct: 1591 SSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMI-----EGNL 1645
Query: 254 LDPVEDTLEVELGKPLTISCKARFGFERVFNPVIKWYIKD 293
P+ +V + LT+ CKA +P++ W +KD
Sbjct: 1646 ATPLNK--QVVIAHSLTLECKAAGN----PSPILTW-LKD 1678
>gi|94420689 neural cell adhesion molecule 1 isoform 1 [Homo
sapiens]
Length = 848
Score = 37.7 bits (86), Expect = 0.030
Identities = 49/251 (19%), Positives = 103/251 (41%), Gaps = 49/251 (19%)
Query: 120 NSGSYICRPKMIKSPYDVACCVKMILEVKPQTNASCEYSASHKQDLLLGSTGSISCPSLS 179
+ G+Y C +++ +++I+ V P A +Q+++ + +L
Sbjct: 183 DEGTYRCEGRILARGEINFKDIQVIVNVPPTIQA--------RQNIVNATANLGQSVTLV 234
Query: 180 CQSDA-QSPAVTWYKNGKLLSVER----------SNRIVVDEVYDYHQGTYVCDYTQSDT 228
C ++ P ++W K+G+ + E S+++ + +V + Y+C
Sbjct: 235 CDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAEN--- 291
Query: 229 VSSWTVRAVVQVRTIVGDTKLKPDILDPVEDTLEVELGKPLTISCKARFGFERVFNPVIK 288
+A Q TI KP I VE+ +EL + +T++C+A +P+
Sbjct: 292 ------KAGEQDATIHLKVFAKPKITY-VENQTAMELEEQVTLTCEASG------DPI-- 336
Query: 289 WYIKDSDLEWEVSVPEAKSIKSTLKDEIIERN------IILEKVTQRDLRRKFVCFVQNS 342
+ W S S + TL ++ R+ + L+ + D +++C N+
Sbjct: 337 -----PSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAG-EYICTASNT 390
Query: 343 IGNTTQSVQLK 353
IG +QS+ L+
Sbjct: 391 IGQDSQSMYLE 401
>gi|115529478 neural cell adhesion molecule 1 isoform 3 [Homo
sapiens]
Length = 761
Score = 37.7 bits (86), Expect = 0.030
Identities = 49/251 (19%), Positives = 103/251 (41%), Gaps = 49/251 (19%)
Query: 120 NSGSYICRPKMIKSPYDVACCVKMILEVKPQTNASCEYSASHKQDLLLGSTGSISCPSLS 179
+ G+Y C +++ +++I+ V P A +Q+++ + +L
Sbjct: 183 DEGTYRCEGRILARGEINFKDIQVIVNVPPTIQA--------RQNIVNATANLGQSVTLV 234
Query: 180 CQSDA-QSPAVTWYKNGKLLSVER----------SNRIVVDEVYDYHQGTYVCDYTQSDT 228
C ++ P ++W K+G+ + E S+++ + +V + Y+C
Sbjct: 235 CDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAEN--- 291
Query: 229 VSSWTVRAVVQVRTIVGDTKLKPDILDPVEDTLEVELGKPLTISCKARFGFERVFNPVIK 288
+A Q TI KP I VE+ +EL + +T++C+A +P+
Sbjct: 292 ------KAGEQDATIHLKVFAKPKITY-VENQTAMELEEQVTLTCEASG------DPI-- 336
Query: 289 WYIKDSDLEWEVSVPEAKSIKSTLKDEIIERN------IILEKVTQRDLRRKFVCFVQNS 342
+ W S S + TL ++ R+ + L+ + D +++C N+
Sbjct: 337 -----PSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAG-EYICTASNT 390
Query: 343 IGNTTQSVQLK 353
IG +QS+ L+
Sbjct: 391 IGQDSQSMYLE 401
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.417
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,657,266
Number of Sequences: 37866
Number of extensions: 1085348
Number of successful extensions: 2917
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 69
Number of HSP's that attempted gapping in prelim test: 2603
Number of HSP's gapped (non-prelim): 360
length of query: 599
length of database: 18,247,518
effective HSP length: 108
effective length of query: 491
effective length of database: 14,157,990
effective search space: 6951573090
effective search space used: 6951573090
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.