Guide to the Human Genome
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Search of human proteins with 4502565

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4502565 calpain, small subunit 1 [Homo sapiens]
         (268 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4502565 calpain, small subunit 1 [Homo sapiens]                    552   e-157
gi|51599151 calpain, small subunit 1 [Homo sapiens]                   552   e-157
gi|14161692 calpain small subunit 2 [Homo sapiens]                    338   3e-93
gi|47078247 calpain 3 isoform f [Homo sapiens]                        224   5e-59
gi|4557405 calpain 3 isoform a [Homo sapiens]                         224   5e-59
gi|27765072 calpain 3 isoform b [Homo sapiens]                        224   5e-59
gi|27765076 calpain 3 isoform d [Homo sapiens]                        224   5e-59
gi|27765074 calpain 3 isoform c [Homo sapiens]                        223   1e-58
gi|27765080 calpain 3 isoform e [Homo sapiens]                        196   1e-50
gi|27765078 calpain 3 isoform e [Homo sapiens]                        196   1e-50
gi|12408656 calpain 1, large subunit [Homo sapiens]                   190   1e-48
gi|157389005 calpain 2 isoform 1 [Homo sapiens]                       180   1e-45
gi|225703100 calpain 2 isoform 2 [Homo sapiens]                       180   1e-45
gi|7705383 calpain 9 isoform 2 [Homo sapiens]                         165   4e-41
gi|5729758 calpain 9 isoform 1 [Homo sapiens]                         165   4e-41
gi|215490104 calpain 11 [Homo sapiens]                                156   2e-38
gi|221554549 calpain 8 [Homo sapiens]                                 150   9e-37
gi|4507207 sorcin isoform a [Homo sapiens]                            106   2e-23
gi|38679884 sorcin isoform b [Homo sapiens]                           105   4e-23
gi|41152101 calpain 13 [Homo sapiens]                                 102   5e-22
gi|6912388 grancalcin, EF-hand calcium binding protein [Homo sap...    98   9e-21
gi|38707981 calpain 12 [Homo sapiens]                                  96   3e-20
gi|6912582 penta-EF-hand domain containing 1 [Homo sapiens]            88   9e-18
gi|223468608 calpain 14 [Homo sapiens]                                 85   6e-17
gi|7019485 programmed cell death 6 [Homo sapiens]                      79   4e-15
gi|109452587 family with sequence similarity 98, member B isofor...    73   2e-13
gi|119395750 keratin 1 [Homo sapiens]                                  67   1e-11
gi|12056465 fibrillarin [Homo sapiens]                                 66   3e-11
gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens]     66   3e-11
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ...    64   1e-10

>gi|4502565 calpain, small subunit 1 [Homo sapiens]
          Length = 268

 Score =  552 bits (1422), Expect = e-157
 Identities = 268/268 (100%), Positives = 268/268 (100%)

Query: 1   MFLVNSFLKGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMR 60
           MFLVNSFLKGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMR
Sbjct: 1   MFLVNSFLKGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMR 60

Query: 61  ILGGVISAISEAAAQYNPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATEL 120
           ILGGVISAISEAAAQYNPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATEL
Sbjct: 61  ILGGVISAISEAAAQYNPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATEL 120

Query: 121 MNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQ 180
           MNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQ
Sbjct: 121 MNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQ 180

Query: 181 FDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMF 240
           FDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMF
Sbjct: 181 FDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMF 240

Query: 241 RAFKSLDKDGTGQIQVNIQEWLQLTMYS 268
           RAFKSLDKDGTGQIQVNIQEWLQLTMYS
Sbjct: 241 RAFKSLDKDGTGQIQVNIQEWLQLTMYS 268


>gi|51599151 calpain, small subunit 1 [Homo sapiens]
          Length = 268

 Score =  552 bits (1422), Expect = e-157
 Identities = 268/268 (100%), Positives = 268/268 (100%)

Query: 1   MFLVNSFLKGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMR 60
           MFLVNSFLKGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMR
Sbjct: 1   MFLVNSFLKGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMR 60

Query: 61  ILGGVISAISEAAAQYNPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATEL 120
           ILGGVISAISEAAAQYNPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATEL
Sbjct: 61  ILGGVISAISEAAAQYNPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATEL 120

Query: 121 MNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQ 180
           MNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQ
Sbjct: 121 MNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQ 180

Query: 181 FDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMF 240
           FDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMF
Sbjct: 181 FDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMF 240

Query: 241 RAFKSLDKDGTGQIQVNIQEWLQLTMYS 268
           RAFKSLDKDGTGQIQVNIQEWLQLTMYS
Sbjct: 241 RAFKSLDKDGTGQIQVNIQEWLQLTMYS 268


>gi|14161692 calpain small subunit 2 [Homo sapiens]
          Length = 248

 Score =  338 bits (867), Expect = 3e-93
 Identities = 172/269 (63%), Positives = 208/269 (77%), Gaps = 22/269 (8%)

Query: 1   MFLVNSFLKGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMR 60
           MFL  + L+G   G          LG  LGGL        GGGG    GGG   GG    
Sbjct: 1   MFLAKALLEGADRG----------LGEALGGLF-------GGGGQRREGGGRNIGG---- 39

Query: 61  ILGGVISAISEAAA-QYNPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATE 119
           I+GG+++ ISEAAA QY PEPPP + H++++EA+ESEEVR+FR+ F QLAG DMEV AT+
Sbjct: 40  IVGGIVNFISEAAAAQYTPEPPPTQQHFTSVEASESEEVRRFRQQFTQLAGPDMEVGATD 99

Query: 120 LMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYK 179
           LMNILNKV+++H DLKTDGF +DTCRS+V+VMDSDTTGKLGFEEFKYLWNNIK+WQ +YK
Sbjct: 100 LMNILNKVLSKHKDLKTDGFSLDTCRSIVSVMDSDTTGKLGFEEFKYLWNNIKKWQCVYK 159

Query: 180 QFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAM 239
           Q+D D SG++ SS+L GA +AAGF LNE LY MI+RRY++E G+MDF+NFISCLVRLDAM
Sbjct: 160 QYDRDHSGSLGSSQLRGALQAAGFQLNEQLYQMIVRRYANEDGDMDFNNFISCLVRLDAM 219

Query: 240 FRAFKSLDKDGTGQIQVNIQEWLQLTMYS 268
           FRAFKSLD+D  G IQV+I+EWLQLTMYS
Sbjct: 220 FRAFKSLDRDRDGLIQVSIKEWLQLTMYS 248


>gi|47078247 calpain 3 isoform f [Homo sapiens]
          Length = 728

 Score =  224 bits (572), Expect = 5e-59
 Identities = 106/192 (55%), Positives = 140/192 (72%), Gaps = 6/192 (3%)

Query: 77  NPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKT 136
           +P+P P  +        ESEE +QFR +F Q+AGDDME+ A EL  +LN VV +H DLKT
Sbjct: 543 SPQPQPGSSD------QESEEQQQFRNIFKQIAGDDMEICADELKKVLNTVVNKHKDLKT 596

Query: 137 DGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPG 196
            GF +++CRSM+A+MD+D +GKL  +EF +LWN IK WQ I+K +DTD+SGTI S E+  
Sbjct: 597 HGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRN 656

Query: 197 AFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQV 256
           A   AGFHLN  LY++I  RY+D+  N+DFD+FI C VRL+ MFRAF + DKDG G I++
Sbjct: 657 AVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKL 716

Query: 257 NIQEWLQLTMYS 268
           N+ EWLQLTMY+
Sbjct: 717 NVLEWLQLTMYA 728


>gi|4557405 calpain 3 isoform a [Homo sapiens]
          Length = 821

 Score =  224 bits (572), Expect = 5e-59
 Identities = 106/192 (55%), Positives = 140/192 (72%), Gaps = 6/192 (3%)

Query: 77  NPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKT 136
           +P+P P  +        ESEE +QFR +F Q+AGDDME+ A EL  +LN VV +H DLKT
Sbjct: 636 SPQPQPGSSD------QESEEQQQFRNIFKQIAGDDMEICADELKKVLNTVVNKHKDLKT 689

Query: 137 DGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPG 196
            GF +++CRSM+A+MD+D +GKL  +EF +LWN IK WQ I+K +DTD+SGTI S E+  
Sbjct: 690 HGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRN 749

Query: 197 AFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQV 256
           A   AGFHLN  LY++I  RY+D+  N+DFD+FI C VRL+ MFRAF + DKDG G I++
Sbjct: 750 AVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKL 809

Query: 257 NIQEWLQLTMYS 268
           N+ EWLQLTMY+
Sbjct: 810 NVLEWLQLTMYA 821


>gi|27765072 calpain 3 isoform b [Homo sapiens]
          Length = 815

 Score =  224 bits (572), Expect = 5e-59
 Identities = 106/192 (55%), Positives = 140/192 (72%), Gaps = 6/192 (3%)

Query: 77  NPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKT 136
           +P+P P  +        ESEE +QFR +F Q+AGDDME+ A EL  +LN VV +H DLKT
Sbjct: 630 SPQPQPGSSD------QESEEQQQFRNIFKQIAGDDMEICADELKKVLNTVVNKHKDLKT 683

Query: 137 DGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPG 196
            GF +++CRSM+A+MD+D +GKL  +EF +LWN IK WQ I+K +DTD+SGTI S E+  
Sbjct: 684 HGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRN 743

Query: 197 AFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQV 256
           A   AGFHLN  LY++I  RY+D+  N+DFD+FI C VRL+ MFRAF + DKDG G I++
Sbjct: 744 AVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKL 803

Query: 257 NIQEWLQLTMYS 268
           N+ EWLQLTMY+
Sbjct: 804 NVLEWLQLTMYA 815


>gi|27765076 calpain 3 isoform d [Homo sapiens]
          Length = 309

 Score =  224 bits (572), Expect = 5e-59
 Identities = 106/192 (55%), Positives = 140/192 (72%), Gaps = 6/192 (3%)

Query: 77  NPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKT 136
           +P+P P  +        ESEE +QFR +F Q+AGDDME+ A EL  +LN VV +H DLKT
Sbjct: 124 SPQPQPGSSD------QESEEQQQFRNIFKQIAGDDMEICADELKKVLNTVVNKHKDLKT 177

Query: 137 DGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPG 196
            GF +++CRSM+A+MD+D +GKL  +EF +LWN IK WQ I+K +DTD+SGTI S E+  
Sbjct: 178 HGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRN 237

Query: 197 AFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQV 256
           A   AGFHLN  LY++I  RY+D+  N+DFD+FI C VRL+ MFRAF + DKDG G I++
Sbjct: 238 AVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKL 297

Query: 257 NIQEWLQLTMYS 268
           N+ EWLQLTMY+
Sbjct: 298 NVLEWLQLTMYA 309


>gi|27765074 calpain 3 isoform c [Homo sapiens]
          Length = 729

 Score =  223 bits (569), Expect = 1e-58
 Identities = 103/175 (58%), Positives = 134/175 (76%)

Query: 94  ESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDS 153
           ESEE +QFR +F Q+AGDDME+ A EL  +LN VV +H DLKT GF +++CRSM+A+MD+
Sbjct: 555 ESEEQQQFRNIFKQIAGDDMEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDT 614

Query: 154 DTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMI 213
           D +GKL  +EF +LWN IK WQ I+K +DTD+SGTI S E+  A   AGFHLN  LY++I
Sbjct: 615 DGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDII 674

Query: 214 IRRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLTMYS 268
             RY+D+  N+DFD+FI C VRL+ MFRAF + DKDG G I++N+ EWLQLTMY+
Sbjct: 675 TMRYADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA 729


>gi|27765080 calpain 3 isoform e [Homo sapiens]
          Length = 156

 Score =  196 bits (499), Expect = 1e-50
 Identities = 90/156 (57%), Positives = 118/156 (75%)

Query: 113 MEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIK 172
           ME+ A EL  +LN VV +H DLKT GF +++CRSM+A+MD+D +GKL  +EF +LWN IK
Sbjct: 1   MEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIK 60

Query: 173 RWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISC 232
            WQ I+K +DTD+SGTI S E+  A   AGFHLN  LY++I  RY+D+  N+DFD+FI C
Sbjct: 61  AWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICC 120

Query: 233 LVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLTMYS 268
            VRL+ MFRAF + DKDG G I++N+ EWLQLTMY+
Sbjct: 121 FVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA 156


>gi|27765078 calpain 3 isoform e [Homo sapiens]
          Length = 156

 Score =  196 bits (499), Expect = 1e-50
 Identities = 90/156 (57%), Positives = 118/156 (75%)

Query: 113 MEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIK 172
           ME+ A EL  +LN VV +H DLKT GF +++CRSM+A+MD+D +GKL  +EF +LWN IK
Sbjct: 1   MEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIK 60

Query: 173 RWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISC 232
            WQ I+K +DTD+SGTI S E+  A   AGFHLN  LY++I  RY+D+  N+DFD+FI C
Sbjct: 61  AWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICC 120

Query: 233 LVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLTMYS 268
            VRL+ MFRAF + DKDG G I++N+ EWLQLTMY+
Sbjct: 121 FVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA 156


>gi|12408656 calpain 1, large subunit [Homo sapiens]
          Length = 714

 Score =  190 bits (482), Expect = 1e-48
 Identities = 88/176 (50%), Positives = 127/176 (72%)

Query: 93  NESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMD 152
           +E E    F+ LF QLAG+DME+S  EL  ILN+++++H DL+T GF +++CRSMV +MD
Sbjct: 539 SEEEIDENFKALFRQLAGEDMEISVKELRTILNRIISKHKDLRTKGFSLESCRSMVNLMD 598

Query: 153 SDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNM 212
            D  GKLG  EF  LWN I+ + +I+++FD D+SG++ + E+  A E+AGF LN+ LY +
Sbjct: 599 RDGNGKLGLVEFNILWNRIRNYLSIFRKFDLDKSGSMSAYEMRMAIESAGFKLNKKLYEL 658

Query: 213 IIRRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLTMYS 268
           II RYS+    +DFDNF+ CLVRL+ MFR FK+LD D  G +  ++ +WLQLTM++
Sbjct: 659 IITRYSEPDLAVDFDNFVCCLVRLETMFRFFKTLDTDLDGVVTFDLFKWLQLTMFA 714


>gi|157389005 calpain 2 isoform 1 [Homo sapiens]
          Length = 700

 Score =  180 bits (457), Expect = 1e-45
 Identities = 87/197 (44%), Positives = 128/197 (64%)

Query: 66  ISAISEAAAQYNPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATELMNILN 125
           I   SE  A Y         +    + +E +    FRRLFAQLAG+D E+SA EL  IL 
Sbjct: 499 IRVFSEKKADYQAVDDEIEANLEEFDISEDDIDDGFRRLFAQLAGEDAEISAFELQTILR 558

Query: 126 KVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDR 185
           +V+ +  D+K+DGF I+TC+ MV ++DSD +GKLG +EF  LW  I+++Q IY++ D DR
Sbjct: 559 RVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTKIQKYQKIYREIDVDR 618

Query: 186 SGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMFRAFKS 245
           SGT+ S E+  A E AGF +   L+ +I+ R++D+   +DFDNF+ CLVRL+ +F+ FK 
Sbjct: 619 SGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIIDFDNFVRCLVRLETLFKIFKQ 678

Query: 246 LDKDGTGQIQVNIQEWL 262
           LD + TG I++++  WL
Sbjct: 679 LDPENTGTIELDLISWL 695


>gi|225703100 calpain 2 isoform 2 [Homo sapiens]
          Length = 622

 Score =  180 bits (457), Expect = 1e-45
 Identities = 87/197 (44%), Positives = 128/197 (64%)

Query: 66  ISAISEAAAQYNPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATELMNILN 125
           I   SE  A Y         +    + +E +    FRRLFAQLAG+D E+SA EL  IL 
Sbjct: 421 IRVFSEKKADYQAVDDEIEANLEEFDISEDDIDDGFRRLFAQLAGEDAEISAFELQTILR 480

Query: 126 KVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDR 185
           +V+ +  D+K+DGF I+TC+ MV ++DSD +GKLG +EF  LW  I+++Q IY++ D DR
Sbjct: 481 RVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTKIQKYQKIYREIDVDR 540

Query: 186 SGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMFRAFKS 245
           SGT+ S E+  A E AGF +   L+ +I+ R++D+   +DFDNF+ CLVRL+ +F+ FK 
Sbjct: 541 SGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIIDFDNFVRCLVRLETLFKIFKQ 600

Query: 246 LDKDGTGQIQVNIQEWL 262
           LD + TG I++++  WL
Sbjct: 601 LDPENTGTIELDLISWL 617


>gi|7705383 calpain 9 isoform 2 [Homo sapiens]
          Length = 664

 Score =  165 bits (417), Expect = 4e-41
 Identities = 80/189 (42%), Positives = 124/189 (65%), Gaps = 5/189 (2%)

Query: 78  PEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTD 137
           PEPP P          E+EE ++FR LF Q+AG+DMEV+A EL  +LN V+ +  D+K  
Sbjct: 479 PEPPKPTP-----PDQETEEEQRFRALFEQVAGEDMEVTAEELEYVLNAVLQKKKDIKFK 533

Query: 138 GFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPGA 197
              + +C++++++MD+   GKL F+EFK  W+ +K+W  ++ +FD D+SGT+ + EL  A
Sbjct: 534 KLSLISCKNIISLMDTSGNGKLEFDEFKVFWDKLKQWINLFLRFDADKSGTMSTYELRTA 593

Query: 198 FEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVN 257
            +AAGF L+ HL  +I+ RY+DE   +DFD+F++CLVRL+   R F++L       I +N
Sbjct: 594 LKAAGFQLSSHLLQLIVLRYADEELQLDFDDFLNCLVRLENASRVFQALSTKNKEFIHLN 653

Query: 258 IQEWLQLTM 266
           I E++ LTM
Sbjct: 654 INEFIHLTM 662


>gi|5729758 calpain 9 isoform 1 [Homo sapiens]
          Length = 690

 Score =  165 bits (417), Expect = 4e-41
 Identities = 80/189 (42%), Positives = 124/189 (65%), Gaps = 5/189 (2%)

Query: 78  PEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTD 137
           PEPP P          E+EE ++FR LF Q+AG+DMEV+A EL  +LN V+ +  D+K  
Sbjct: 505 PEPPKPTP-----PDQETEEEQRFRALFEQVAGEDMEVTAEELEYVLNAVLQKKKDIKFK 559

Query: 138 GFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPGA 197
              + +C++++++MD+   GKL F+EFK  W+ +K+W  ++ +FD D+SGT+ + EL  A
Sbjct: 560 KLSLISCKNIISLMDTSGNGKLEFDEFKVFWDKLKQWINLFLRFDADKSGTMSTYELRTA 619

Query: 198 FEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVN 257
            +AAGF L+ HL  +I+ RY+DE   +DFD+F++CLVRL+   R F++L       I +N
Sbjct: 620 LKAAGFQLSSHLLQLIVLRYADEELQLDFDDFLNCLVRLENASRVFQALSTKNKEFIHLN 679

Query: 258 IQEWLQLTM 266
           I E++ LTM
Sbjct: 680 INEFIHLTM 688


>gi|215490104 calpain 11 [Homo sapiens]
          Length = 739

 Score =  156 bits (395), Expect = 2e-38
 Identities = 71/177 (40%), Positives = 111/177 (62%)

Query: 91  EANESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAV 150
           + +E +  + F  LF  +AG+  E+   EL  +LN++  +    KT GFG+D CR M+ +
Sbjct: 562 KVSEDDMDQDFLHLFKIVAGEGKEIGVYELQRLLNRMAIKFKSFKTKGFGLDACRCMINL 621

Query: 151 MDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLY 210
           MD D +GKLG  EFK LW  +K+W  I+++ D D SGT+ S E+    E AG  LN  + 
Sbjct: 622 MDKDGSGKLGLLEFKILWKKLKKWMDIFRECDQDHSGTLNSYEMRLVIEKAGIKLNNKVM 681

Query: 211 NMIIRRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLTMY 267
            +++ RY+D+   +DFD+FISC +RL  MF  F ++D   TG I +++++WLQ+TM+
Sbjct: 682 QVLVARYADDDLIIDFDSFISCFLRLKTMFTFFLTMDPKNTGHICLSLEQWLQMTMW 738


>gi|221554549 calpain 8 [Homo sapiens]
          Length = 703

 Score =  150 bits (380), Expect = 9e-37
 Identities = 74/181 (40%), Positives = 115/181 (63%), Gaps = 4/181 (2%)

Query: 82  PPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGI 141
           P   H S ++    +E  QFRRLF +LAG D E++A  L  +LN+  ++  D+K DGF I
Sbjct: 522 PYEPHPSEVD----QEDDQFRRLFEKLAGKDSEITANALKILLNEAFSKRTDIKFDGFNI 577

Query: 142 DTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAA 201
           +TCR M++++DS+ TG LG  EFK LW  I+++  IY + D + SGTI + E+  A   A
Sbjct: 578 NTCREMISLLDSNGTGTLGAVEFKTLWLKIQKYLEIYWETDYNHSGTIDAHEMRTALRKA 637

Query: 202 GFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEW 261
           GF LN  +   I  RY+     ++FD+F++C++RL+ +F+ F  LD+D  G +Q+++ EW
Sbjct: 638 GFTLNSQVQQTIALRYACSKLGINFDSFVACMIRLETLFKLFSLLDEDKDGMVQLSLAEW 697

Query: 262 L 262
           L
Sbjct: 698 L 698


>gi|4507207 sorcin isoform a [Homo sapiens]
          Length = 198

 Score =  106 bits (264), Expect = 2e-23
 Identities = 72/230 (31%), Positives = 104/230 (45%), Gaps = 38/230 (16%)

Query: 37  GGGGGGGGGGGGGGGGGGGGTAMRILGGVISAISEAAAQYNPEPPPPRTHYSNIEANESE 96
           G  G GGG   GG GG  GG A                 +  +   P   Y         
Sbjct: 5   GHPGAGGGYYPGGYGGAPGGPA-----------------FPGQTQDPLYGY--------- 38

Query: 97  EVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTT 156
                   FA +AG D ++ A EL   L +            F ++TCR MV+++D D +
Sbjct: 39  --------FAAVAGQDGQIDADELQRCLTQSGIAGG---YKPFNLETCRLMVSMLDRDMS 87

Query: 157 GKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRR 216
           G +GF EFK LW  +  W+  +  FDTDRSGT+   EL  A    GF L+    N I +R
Sbjct: 88  GTMGFNEFKELWAVLNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKR 147

Query: 217 YSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLTM 266
           YS  +G + FD++I+C V+L A+  +F+  D    G +     +++Q  M
Sbjct: 148 YS-TNGKITFDDYIACCVKLRALTDSFRRRDTAQQGVVNFPYDDFIQCVM 196


>gi|38679884 sorcin isoform b [Homo sapiens]
          Length = 183

 Score =  105 bits (262), Expect = 4e-23
 Identities = 58/162 (35%), Positives = 88/162 (54%), Gaps = 4/162 (2%)

Query: 105 FAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEF 164
           FA +AG D ++ A EL   L +            F ++TCR MV+++D D +G +GF EF
Sbjct: 24  FAAVAGQDGQIDADELQRCLTQSGIAGG---YKPFNLETCRLMVSMLDRDMSGTMGFNEF 80

Query: 165 KYLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNM 224
           K LW  +  W+  +  FDTDRSGT+   EL  A    GF L+    N I +RYS  +G +
Sbjct: 81  KELWAVLNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYS-TNGKI 139

Query: 225 DFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLTM 266
            FD++I+C V+L A+  +F+  D    G +     +++Q  M
Sbjct: 140 TFDDYIACCVKLRALTDSFRRRDTAQQGVVNFPYDDFIQCVM 181


>gi|41152101 calpain 13 [Homo sapiens]
          Length = 669

 Score =  102 bits (253), Expect = 5e-22
 Identities = 60/189 (31%), Positives = 106/189 (56%), Gaps = 10/189 (5%)

Query: 85  THYS-NIEANESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDT 143
           +H++  ++ + SE   Q + +F + A   +++ AT+L  +LN+ +   P    D F +D 
Sbjct: 486 SHFNLRMKGSPSEHGSQ-QSIFNRYAQQRLDIDATQLQGLLNQELLTGPP--GDMFSLDE 542

Query: 144 CRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAA-- 201
           CRS+VA+M+    G+L  EEF  LW  +  +Q ++++  T   G + SS+L  A E    
Sbjct: 543 CRSLVALMELKVNGRLDQEEFARLWKRLVHYQHVFQKVQTS-PGVLLSSDLWKAIENTDF 601

Query: 202 --GFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQ 259
             G  ++  L +++  RYSD  G + F + +  L+RL+AM + F++L KDG G + +   
Sbjct: 602 LRGIFISRELLHLVTLRYSDSVGRVSFPSLVCFLMRLEAMAKTFRNLSKDGKG-LYLTEM 660

Query: 260 EWLQLTMYS 268
           EW+ L MY+
Sbjct: 661 EWMSLVMYN 669


>gi|6912388 grancalcin, EF-hand calcium binding protein [Homo
           sapiens]
          Length = 217

 Score = 97.8 bits (242), Expect = 9e-21
 Identities = 59/180 (32%), Positives = 93/180 (51%), Gaps = 7/180 (3%)

Query: 87  YSNIEANESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRS 146
           YS+  ++  + V  +   F+ +AG D EV A EL   L +            F ++TCR 
Sbjct: 43  YSDTYSSAGDSVYTY---FSAVAGQDGEVDAEELQRCLTQSGINGT---YSPFSLETCRI 96

Query: 147 MVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLN 206
           M+A++D D TGK+GF  FK LW  +  W+  +   D D SGT+   EL  A    G+ L+
Sbjct: 97  MIAMLDRDHTGKMGFNAFKELWAALNAWKENFMTVDQDGSGTVEHHELRQAIGLMGYRLS 156

Query: 207 EHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLTM 266
                 I++RYS ++G + FD++++C V+L A+   F+  D    G       ++LQ TM
Sbjct: 157 PQTLTTIVKRYS-KNGRIFFDDYVACCVKLRALTDFFRKRDHLQQGSANFIYDDFLQGTM 215


>gi|38707981 calpain 12 [Homo sapiens]
          Length = 719

 Score = 96.3 bits (238), Expect = 3e-20
 Identities = 54/168 (32%), Positives = 87/168 (51%), Gaps = 4/168 (2%)

Query: 103 RLFAQLAGDDMEVSATELMNILNKVV--TRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLG 160
           +LF +LAG++ E++A++L  +L+  +   R         G+ TC  ++       +  L 
Sbjct: 554 QLFQELAGEEEELNASQLQALLSIALEPARAHTSTPREIGLRTCEQLLQCFGHGQS--LA 611

Query: 161 FEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDE 220
              F+ LW  +  WQAI+ +FD D SGT+ S EL  A  AAGFHLN  L   +  RY D 
Sbjct: 612 LHHFQQLWGYLLEWQAIFNKFDEDTSGTMNSYELRLALNAAGFHLNNQLTQTLTSRYRDS 671

Query: 221 SGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLTMYS 268
              +DF+ F+SC+  L  +F         G G I +  ++W+++  +S
Sbjct: 672 RLRVDFERFVSCVAHLTCIFCHCSQHLDGGEGVICLTHRQWMEVATFS 719


>gi|6912582 penta-EF-hand domain containing 1 [Homo sapiens]
          Length = 284

 Score = 87.8 bits (216), Expect = 9e-18
 Identities = 71/258 (27%), Positives = 110/258 (42%), Gaps = 26/258 (10%)

Query: 13  GGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMRILGGVISAISEA 72
           GGG GG   GG  G   GG   G  G    G    G  GG  GG A     G     S  
Sbjct: 43  GGGYGGPAPGGPYGPPAGG---GPYGHPNPGMFPSGTPGGPYGGAAPGGPYGQPPPSSYG 99

Query: 73  AAQ---YNPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVT 129
           A Q   Y     PP          + E    F+ + +  +G    +S  EL   L     
Sbjct: 100 AQQPGLYGQGGAPPNV--------DPEAYSWFQSVDSDHSG---YISMKELKQAL----- 143

Query: 130 RHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTI 189
              +     F  +TC  M+ + D   +G++    F  LW  I++W+ +++Q+D DRSG+I
Sbjct: 144 --VNCNWSSFNDETCLMMINMFDKTKSGRIDVYGFSALWKFIQQWKNLFQQYDRDRSGSI 201

Query: 190 CSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGN--MDFDNFISCLVRLDAMFRAFKSLD 247
             +EL  A    G++L+     +++ RY   S N  M  D FI    +L  +  AF+  D
Sbjct: 202 SYTELQQALSQMGYNLSPQFTQLLVSRYCPRSANPAMQLDRFIQVCTQLQVLTEAFREKD 261

Query: 248 KDGTGQIQVNIQEWLQLT 265
               G I+++ ++++ +T
Sbjct: 262 TAVQGNIRLSFEDFVTMT 279


>gi|223468608 calpain 14 [Homo sapiens]
          Length = 684

 Score = 85.1 bits (209), Expect = 6e-17
 Identities = 44/155 (28%), Positives = 87/155 (56%), Gaps = 2/155 (1%)

Query: 114 EVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKR 173
           E++A +L N+LN++       +   F ++ C+ ++A++D + +G +  +EF+ LW  +K 
Sbjct: 532 EINAVQLQNLLNQMTWSSLGSRQPFFSLEACQGILALLDLNASGTMSIQEFRDLWKQLKL 591

Query: 174 WQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCL 233
            Q ++ + D   SG +   +L  A   AG  L++ +  +++ RY      MDF +FI  +
Sbjct: 592 SQKVFHKQDRG-SGYLNWEQLHAAMREAGIMLSDDVCQLMLIRYGGPRLQMDFVSFIHLM 650

Query: 234 VRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLTMYS 268
           +R++ M   F++L +DG G I +   EW+ + +YS
Sbjct: 651 LRVENMEDVFQNLTQDGKG-IYLQKPEWMMMALYS 684


>gi|7019485 programmed cell death 6 [Homo sapiens]
          Length = 191

 Score = 79.0 bits (193), Expect = 4e-15
 Identities = 37/123 (30%), Positives = 69/123 (56%), Gaps = 1/123 (0%)

Query: 143 TCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAG 202
           T RS++++ D +    + F EF  +W  I  WQ +++ +D D SG I  +EL  A    G
Sbjct: 64  TVRSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALSGFG 123

Query: 203 FHLNEHLYNMIIRRYSDES-GNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEW 261
           + L++  ++++IR++  +  G + FD+FI   + L  +   F+  D D  G IQV+ +++
Sbjct: 124 YRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQY 183

Query: 262 LQL 264
           L +
Sbjct: 184 LSM 186



 Score = 33.1 bits (74), Expect = 0.26
 Identities = 24/94 (25%), Positives = 40/94 (42%), Gaps = 9/94 (9%)

Query: 166 YLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGF-HLNEHLYNMIIRRYSDES-GN 223
           +LWN       ++++ D DRSG I  +EL  A     +   N      II  +  E+   
Sbjct: 27  FLWN-------VFQRVDKDRSGVISDTELQQALSNGTWTPFNPVTVRSIISMFDRENKAG 79

Query: 224 MDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVN 257
           ++F  F      +      F++ D+D +G I  N
Sbjct: 80  VNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKN 113


>gi|109452587 family with sequence similarity 98, member B isoform 1
           [Homo sapiens]
          Length = 433

 Score = 73.2 bits (178), Expect = 2e-13
 Identities = 34/48 (70%), Positives = 35/48 (72%)

Query: 9   KGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGG 56
           +GG GGGGGGGG GGG G    G   G GGG GGGGGGGGG GGGGGG
Sbjct: 335 RGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGG 382



 Score = 72.8 bits (177), Expect = 3e-13
 Identities = 35/47 (74%), Positives = 35/47 (74%), Gaps = 2/47 (4%)

Query: 10  GGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGG 56
           GGGGGGGG GG GGG G   GG   G GG GGGGGGGGG GGGGGGG
Sbjct: 339 GGGGGGGGRGGGGGGGGR--GGWGGGGGGWGGGGGGGGGWGGGGGGG 383



 Score = 71.2 bits (173), Expect = 9e-13
 Identities = 35/47 (74%), Positives = 35/47 (74%), Gaps = 1/47 (2%)

Query: 10  GGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGG 56
           GGGGGG GGGG GGG G   GG   G GGGGGGGGG GGGGGGG GG
Sbjct: 341 GGGGGGRGGGGGGGGRGG-WGGGGGGWGGGGGGGGGWGGGGGGGRGG 386



 Score = 68.6 bits (166), Expect = 6e-12
 Identities = 33/47 (70%), Positives = 33/47 (70%)

Query: 10  GGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGG 56
           GGG GG GGGG GGG G   GG   G  GGGGGG GGGGGGGGG GG
Sbjct: 332 GGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGG 378



 Score = 61.6 bits (148), Expect = 7e-10
 Identities = 36/69 (52%), Positives = 36/69 (52%), Gaps = 22/69 (31%)

Query: 10  GGGGGGGGGGGLGGGLGNVLG---------GLISGAGGGGG-------------GGGGGG 47
           GGGGG GGGGG GGG G   G         G   G GG GG             GGGGGG
Sbjct: 361 GGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGG 420

Query: 48  GGGGGGGGG 56
           GGGGGGGGG
Sbjct: 421 GGGGGGGGG 429



 Score = 60.8 bits (146), Expect = 1e-09
 Identities = 32/52 (61%), Positives = 33/52 (63%), Gaps = 14/52 (26%)

Query: 9   KGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGG----GGGGGGGGGGGG 56
           +GGGG GG GGG GGG          G GGGGGGGG    GGGGGG GGGGG
Sbjct: 330 EGGGGRGGWGGGGGGG----------GRGGGGGGGGRGGWGGGGGGWGGGGG 371



 Score = 59.3 bits (142), Expect = 3e-09
 Identities = 38/83 (45%), Positives = 38/83 (45%), Gaps = 34/83 (40%)

Query: 10  GGGGG----GGGGGGLGGGLGNVLGGLISGAGGGGGGG---------------------- 43
           GGGGG    GGGGGG GGG G   GG   G GGGG GG                      
Sbjct: 351 GGGGGRGGWGGGGGGWGGGGGG--GGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGR 408

Query: 44  ------GGGGGGGGGGGGGTAMR 60
                 GGGGGGGGGGGGG   R
Sbjct: 409 GYGDPYGGGGGGGGGGGGGGGYR 431



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 20/30 (66%), Positives = 20/30 (66%)

Query: 35  GAGGGGGGGGGGGGGGGGGGGGTAMRILGG 64
           G G GG GGGGGGGG GGGGGG      GG
Sbjct: 332 GGGRGGWGGGGGGGGRGGGGGGGGRGGWGG 361



 Score = 30.0 bits (66), Expect = 2.2
 Identities = 14/21 (66%), Positives = 14/21 (66%)

Query: 44  GGGGGGGGGGGGGTAMRILGG 64
           GGGG GG GGGGG   R  GG
Sbjct: 331 GGGGRGGWGGGGGGGGRGGGG 351


>gi|119395750 keratin 1 [Homo sapiens]
          Length = 644

 Score = 67.4 bits (163), Expect = 1e-11
 Identities = 38/97 (39%), Positives = 48/97 (49%)

Query: 10  GGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMRILGGVISAI 69
           GGG GGGG GG G G G + GG   G G GGGG GGGG GGGG GGG       G I  +
Sbjct: 96  GGGFGGGGFGGGGFGGGGIGGGGFGGFGSGGGGFGGGGFGGGGYGGGYGPVCPPGGIQEV 155

Query: 70  SEAAAQYNPEPPPPRTHYSNIEANESEEVRQFRRLFA 106
           +   +   P           +++ E E+++     FA
Sbjct: 156 TINQSLLQPLNVEIDPEIQKVKSREREQIKSLNNQFA 192



 Score = 61.2 bits (147), Expect = 9e-10
 Identities = 31/56 (55%), Positives = 36/56 (64%), Gaps = 3/56 (5%)

Query: 5   NSFLKGGG--GGGGGGGGLGG-GLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGT 57
           +S+  GGG  G GGGGGG G  G G+  GG   G+GGGGGG  GG G GGG  GG+
Sbjct: 557 SSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGS 612



 Score = 60.8 bits (146), Expect = 1e-09
 Identities = 31/47 (65%), Positives = 31/47 (65%)

Query: 10  GGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGG 56
           GGG GGGG GG G G G   GG I G G GG G GGGG GGGG GGG
Sbjct: 91  GGGYGGGGFGGGGFGGGGFGGGGIGGGGFGGFGSGGGGFGGGGFGGG 137



 Score = 58.9 bits (141), Expect = 4e-09
 Identities = 37/77 (48%), Positives = 38/77 (49%), Gaps = 6/77 (7%)

Query: 6   SFLKGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMRILGGV 65
           S  +GGG G G GGG GGG G   GG   G  GGGG GGGG GG G GGGG      GG 
Sbjct: 79  SVARGGGRGSGFGGGYGGG-GFGGGGFGGGGFGGGGIGGGGFGGFGSGGGGFGGGGFGG- 136

Query: 66  ISAISEAAAQYNPEPPP 82
                     Y P  PP
Sbjct: 137 ----GGYGGGYGPVCPP 149



 Score = 58.9 bits (141), Expect = 4e-09
 Identities = 30/56 (53%), Positives = 34/56 (60%), Gaps = 1/56 (1%)

Query: 10  GGGGGGGGGGGLGGGLGNVLGGLISGA-GGGGGGGGGGGGGGGGGGGGTAMRILGG 64
           G GGG  G GG GGG G+   G  SG   GG GGGGGG  GG G GGG++   +GG
Sbjct: 560 GSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGG 615



 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 32/63 (50%), Positives = 34/63 (53%), Gaps = 14/63 (22%)

Query: 8   LKGGGGGGGGGGGLG-GGLGNVLGGLISGAGGGGGGG-------------GGGGGGGGGG 53
           + GGG  GGGGGG G GG     GG   G+GGGGGGG             GGG  G GGG
Sbjct: 512 ISGGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGG 571

Query: 54  GGG 56
           GGG
Sbjct: 572 GGG 574



 Score = 55.8 bits (133), Expect = 4e-08
 Identities = 32/72 (44%), Positives = 38/72 (52%), Gaps = 3/72 (4%)

Query: 6   SFLKGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGG-GTAMRILGG 64
           S+  GGGGGG G  G G   G   GG  SG GGGG  GG G GGG  GG  G      GG
Sbjct: 565 SYGSGGGGGGHGSYGSGSSSGGYRGG--SGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGG 622

Query: 65  VISAISEAAAQY 76
           V S+   ++ ++
Sbjct: 623 VKSSGGSSSVKF 634



 Score = 55.5 bits (132), Expect = 5e-08
 Identities = 35/78 (44%), Positives = 40/78 (51%), Gaps = 19/78 (24%)

Query: 5   NSFLKGGGGGGGGGGGLGGGLGNV-LGGLISGAGGGGGGGGGGGGG-------------- 49
           +S+  GGG  G GGGG GGG G+   GG   G+GGG  G GGGGGG              
Sbjct: 530 SSYGSGGGSYGSGGGG-GGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYR 588

Query: 50  ---GGGGGGGTAMRILGG 64
              GGGGGG +  R  GG
Sbjct: 589 GGSGGGGGGSSGGRGSGG 606



 Score = 54.7 bits (130), Expect = 8e-08
 Identities = 31/67 (46%), Positives = 32/67 (47%), Gaps = 20/67 (29%)

Query: 10  GGGGGGGGGGGL--------------------GGGLGNVLGGLISGAGGGGGGGGGGGGG 49
           GGGG  G GGG                     GGG G+  GG   G G GGGG GGGG G
Sbjct: 51  GGGGSFGAGGGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFG 110

Query: 50  GGGGGGG 56
           GGG GGG
Sbjct: 111 GGGIGGG 117



 Score = 52.0 bits (123), Expect = 5e-07
 Identities = 38/82 (46%), Positives = 39/82 (47%), Gaps = 27/82 (32%)

Query: 10  GGGGG-----GGGGG--GLGGGLGNVL-----------------GGLISGAGGGGGGG-- 43
           GGGGG     GGGGG  G GGG G+                   GG  SG GGG GGG  
Sbjct: 40  GGGGGRFSSCGGGGGSFGAGGGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGF 99

Query: 44  -GGGGGGGGGGGGGTAMRILGG 64
            GGG GGGG GGGG      GG
Sbjct: 100 GGGGFGGGGFGGGGIGGGGFGG 121



 Score = 38.9 bits (89), Expect = 0.005
 Identities = 26/78 (33%), Positives = 34/78 (43%), Gaps = 4/78 (5%)

Query: 2  FLVNSFLKGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGG----GGGGGGGGGGGGGGT 57
          F   S  + GGG   G  G+              +GGGGG     GGGGG  G GGG G+
Sbjct: 5  FSSRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGGFGS 64

Query: 58 AMRILGGVISAISEAAAQ 75
             +  G   +IS + A+
Sbjct: 65 RSLVNLGGSKSISISVAR 82


>gi|12056465 fibrillarin [Homo sapiens]
          Length = 321

 Score = 66.2 bits (160), Expect = 3e-11
 Identities = 32/47 (68%), Positives = 32/47 (68%), Gaps = 2/47 (4%)

Query: 10 GGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGG 56
          G  GG GG GG GGG G   GG   G G GGGGGGGGGGGGG GGGG
Sbjct: 19 GDRGGRGGRGGFGGGRGR--GGGFRGRGRGGGGGGGGGGGGGRGGGG 63



 Score = 59.3 bits (142), Expect = 3e-09
 Identities = 32/56 (57%), Positives = 33/56 (58%), Gaps = 3/56 (5%)

Query: 9  KGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMRILGG 64
          +GG GG GGG G GGG      G   G GGGGGGGGGG GGGG   GG   R  GG
Sbjct: 24 RGGRGGFGGGRGRGGGFRGRGRG---GGGGGGGGGGGGRGGGGFHSGGNRGRGRGG 76



 Score = 58.5 bits (140), Expect = 6e-09
 Identities = 32/52 (61%), Positives = 33/52 (63%), Gaps = 5/52 (9%)

Query: 9  KGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGG----GGGGGGGGGGGGGGG 56
          +GGG GG GG G  GG G   GG   G G GGG    G GGGGGGGGGGGGG
Sbjct: 8  RGGGFGGRGGFGDRGGRGG-RGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGG 58



 Score = 44.7 bits (104), Expect = 9e-05
 Identities = 23/43 (53%), Positives = 24/43 (55%)

Query: 9  KGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGG 51
          +G G GGGGGGG GGG G   GG  SG   G G GG  G   G
Sbjct: 41 RGRGRGGGGGGGGGGGGGRGGGGFHSGGNRGRGRGGKRGNQSG 83



 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 26/52 (50%), Positives = 27/52 (51%), Gaps = 12/52 (23%)

Query: 9  KGGG----GGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGG 56
          +GGG    G GGGGGG GGG G        G GGGG   GG  G G GG  G
Sbjct: 36 RGGGFRGRGRGGGGGGGGGGGG--------GRGGGGFHSGGNRGRGRGGKRG 79


>gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens]
          Length = 532

 Score = 66.2 bits (160), Expect = 3e-11
 Identities = 31/49 (63%), Positives = 32/49 (65%), Gaps = 9/49 (18%)

Query: 10  GGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTA 58
           GG G GG GGG GGG         SG+GGGGGG GGGGGG  GGG GTA
Sbjct: 478 GGSGSGGAGGGSGGG---------SGSGGGGGGAGGGGGGSSGGGSGTA 517



 Score = 28.1 bits (61), Expect = 8.4
 Identities = 13/25 (52%), Positives = 13/25 (52%)

Query: 10  GGGGGGGGGGGLGGGLGNVLGGLIS 34
           G GGGGGG  G G G      GL S
Sbjct: 501 GAGGGGGGSSGGGSGTAGGHSGLSS 525


>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2
           [Homo sapiens]
          Length = 2191

 Score = 63.9 bits (154), Expect = 1e-10
 Identities = 41/91 (45%), Positives = 46/91 (50%), Gaps = 26/91 (28%)

Query: 10  GGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGG------------GGGGGGGGGGG---- 53
           G GGGGGGGGG GGG G   GG  +GAGG G G             GGGGGGG GG    
Sbjct: 247 GAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAG 306

Query: 54  ----------GGGTAMRILGGVISAISEAAA 74
                     GGG  M   GG  +++S+AAA
Sbjct: 307 YGVLSSPRQQGGGMMMGPGGGGAASLSKAAA 337



 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 35/80 (43%), Positives = 40/80 (50%), Gaps = 28/80 (35%)

Query: 7   FLKGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGG----------------- 49
           + + G GGGGGGGG GGG          G+GGGGGGGG G GG                 
Sbjct: 243 YSRPGAGGGGGGGGGGGG----------GSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAA 292

Query: 50  GGGGGGGTAMRILG-GVISA 68
           GGGGGGG      G GV+S+
Sbjct: 293 GGGGGGGYGGSSAGYGVLSS 312



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 21/51 (41%), Positives = 24/51 (47%), Gaps = 6/51 (11%)

Query: 11  GGGGGGGGGGLGGGLGNVL------GGLISGAGGGGGGGGGGGGGGGGGGG 55
           GGGGGGG GG   G G +       GG++ G GGGG         G   GG
Sbjct: 293 GGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGG 343


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.140    0.426 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,019,029
Number of Sequences: 37866
Number of extensions: 722942
Number of successful extensions: 41881
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 753
Number of HSP's successfully gapped in prelim test: 175
Number of HSP's that attempted gapping in prelim test: 10669
Number of HSP's gapped (non-prelim): 10804
length of query: 268
length of database: 18,247,518
effective HSP length: 100
effective length of query: 168
effective length of database: 14,460,918
effective search space: 2429434224
effective search space used: 2429434224
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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