Search of human proteins with 41350214

Search of human proteins with 41350214

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|41350214 asporin [Homo sapiens]
         (380 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|41350214 asporin [Homo sapiens]                                    774   0.0  
gi|4502403 biglycan preproprotein [Homo sapiens]                      398   e-111
gi|19743846 decorin isoform a preproprotein [Homo sapiens]            369   e-102
gi|4503271 decorin isoform a preproprotein [Homo sapiens]             369   e-102
gi|19743848 decorin isoform b precursor [Homo sapiens]                212   5e-55
gi|19743850 decorin isoform c precursor [Homo sapiens]                176   4e-44
gi|4505047 lumican precursor [Homo sapiens]                           147   2e-35
gi|4557543 extracellular matrix protein 2 precursor [Homo sapiens]    140   2e-33
gi|4826876 osteomodulin [Homo sapiens]                                139   6e-33
gi|41349454 proline arginine-rich end leucine-rich repeat protei...   137   2e-32
gi|4506041 proline arginine-rich end leucine-rich repeat protein...   137   2e-32
gi|34577057 fibronectin leucine rich transmembrane protein 1 [Ho...   135   6e-32
gi|5901992 keratocan [Homo sapiens]                                   129   4e-30
gi|38202222 fibronectin leucine rich transmembrane protein 3 pre...   125   8e-29
gi|7019383 fibronectin leucine rich transmembrane protein 3 prec...   125   8e-29
gi|226342933 podocan-like 1 isoform 2 [Homo sapiens]                  124   2e-28
gi|226342931 podocan-like 1 isoform 1 [Homo sapiens]                  124   2e-28
gi|71040111 fibromodulin precursor [Homo sapiens]                     122   7e-28
gi|7019381 fibronectin leucine rich transmembrane protein 2 [Hom...   117   2e-26
gi|45505137 podocan [Homo sapiens]                                    113   3e-25
gi|157694513 leucine-rich repeat-containing G protein-coupled re...   111   1e-24
gi|109809759 leucine rich repeat transmembrane neuronal 3 [Homo ...   108   1e-23
gi|54607118 leucine-rich repeats and immunoglobulin-like domains...   108   1e-23
gi|153251229 chondroadherin precursor [Homo sapiens]                  107   2e-23
gi|188528675 slit homolog 1 [Homo sapiens]                            103   2e-22
gi|198041768 synleurin [Homo sapiens]                                 103   3e-22
gi|205277468 leucine rich repeat containing 15 isoform a [Homo s...   102   7e-22
gi|18677767 leucine rich repeat containing 15 isoform b [Homo sa...   102   7e-22
gi|156139147 leucine rich repeat transmembrane neuronal 4 isofor...   101   1e-21
gi|197927168 leucine rich repeat transmembrane neuronal 4 isofor...   101   1e-21

>gi|41350214 asporin [Homo sapiens]
          Length = 380

 Score =  774 bits (1998), Expect = 0.0
 Identities = 380/380 (100%), Positives = 380/380 (100%)

Query: 1   MKEYVLLLFLALCSAKPFFSPSHIALKNMMLKDMEDTDDDDDDDDDDDDDDEDNSLFPTR 60
           MKEYVLLLFLALCSAKPFFSPSHIALKNMMLKDMEDTDDDDDDDDDDDDDDEDNSLFPTR
Sbjct: 1   MKEYVLLLFLALCSAKPFFSPSHIALKNMMLKDMEDTDDDDDDDDDDDDDDEDNSLFPTR 60

Query: 61  EPRSHFFPFDLFPMCPFGCQCYSRVVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKEN 120
           EPRSHFFPFDLFPMCPFGCQCYSRVVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKEN
Sbjct: 61  EPRSHFFPFDLFPMCPFGCQCYSRVVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKEN 120

Query: 121 DFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLNLPKSLAELRIHE 180
           DFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLNLPKSLAELRIHE
Sbjct: 121 DFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLNLPKSLAELRIHE 180

Query: 181 NKVKKIQKDTFKGMNALHVLEMSANPLDNNGIEPGAFEGVTVFHIRIAEAKLTSVPKGLP 240
           NKVKKIQKDTFKGMNALHVLEMSANPLDNNGIEPGAFEGVTVFHIRIAEAKLTSVPKGLP
Sbjct: 181 NKVKKIQKDTFKGMNALHVLEMSANPLDNNGIEPGAFEGVTVFHIRIAEAKLTSVPKGLP 240

Query: 241 PTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIENGSLANIPRVREIHLENNK 300
           PTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIENGSLANIPRVREIHLENNK
Sbjct: 241 PTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIENGSLANIPRVREIHLENNK 300

Query: 301 LKKIPSGLPELKYLQIIFLHSNSIARVGVNDFCPTVPKMKKSLYSAISLFNNPVKYWEMQ 360
           LKKIPSGLPELKYLQIIFLHSNSIARVGVNDFCPTVPKMKKSLYSAISLFNNPVKYWEMQ
Sbjct: 301 LKKIPSGLPELKYLQIIFLHSNSIARVGVNDFCPTVPKMKKSLYSAISLFNNPVKYWEMQ 360

Query: 361 PATFRCVLSRMSVQLGNFGM 380
           PATFRCVLSRMSVQLGNFGM
Sbjct: 361 PATFRCVLSRMSVQLGNFGM 380


>gi|4502403 biglycan preproprotein [Homo sapiens]
          Length = 368

 Score =  398 bits (1023), Expect = e-111
 Identities = 183/305 (60%), Positives = 241/305 (79%)

Query: 74  MCPFGCQCYSRVVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGLIL 133
           MCPFGC C+ RVV CSDLGL SVP  I  DT +LDLQNN I E++++DFKGL  LY L+L
Sbjct: 62  MCPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVL 121

Query: 134 NNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLNLPKSLAELRIHENKVKKIQKDTFKG 193
            NNK++KIH KAF   +KL++LY+S N L EIP NLP SL ELRIH+N+++K+ K  F G
Sbjct: 122 VNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSG 181

Query: 194 MNALHVLEMSANPLDNNGIEPGAFEGVTVFHIRIAEAKLTSVPKGLPPTLLELHLDYNKI 253
           +  ++ +EM  NPL+N+G EPGAF+G+ + ++RI+EAKLT +PK LP TL ELHLD+NKI
Sbjct: 182 LRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNKI 241

Query: 254 STVELEDFKRYKELQRLGLGNNKITDIENGSLANIPRVREIHLENNKLKKIPSGLPELKY 313
             +ELED  RY +L RLGLG+N+I  IENGSL+ +P +RE+HL+NNKL ++PSGLP+LK 
Sbjct: 242 QAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLARVPSGLPDLKL 301

Query: 314 LQIIFLHSNSIARVGVNDFCPTVPKMKKSLYSAISLFNNPVKYWEMQPATFRCVLSRMSV 373
           LQ+++LHSN+I +VGVNDFCP    +K++ Y+ ISLFNNPV YWE+QPATFRCV  R+++
Sbjct: 302 LQVVYLHSNNITKVGVNDFCPMGFGVKRAYYNGISLFNNPVPYWEVQPATFRCVTDRLAI 361

Query: 374 QLGNF 378
           Q GN+
Sbjct: 362 QFGNY 366


>gi|19743846 decorin isoform a preproprotein [Homo sapiens]
          Length = 359

 Score =  369 bits (947), Expect = e-102
 Identities = 191/380 (50%), Positives = 256/380 (67%), Gaps = 24/380 (6%)

Query: 1   MKEYVLLLFLALCS-AKPFFSPSHIALKNMMLKDMEDTDDDDDDDDDDDDDDEDNSLFPT 59
           MK  ++LL LA  S A PF       L + ML+D       +  DD D            
Sbjct: 1   MKATIILLLLAQVSWAGPF---QQRGLFDFMLEDEASGIGPEVPDDRD------------ 45

Query: 60  REPRSHFFPFDLFPMCPFGCQCYSRVVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKE 119
                  F   L P+CPF CQC+ RVV CSDLGL  VP ++P DT +LDLQNNKI EIK+
Sbjct: 46  -------FEPSLGPVCPFRCQCHLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKD 98

Query: 120 NDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLNLPKSLAELRIH 179
            DFK L +L+ LIL NNK++K+ P AF    KL RLYLS NQL E+P  +PK+L ELR H
Sbjct: 99  GDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKELPEKMPKTLQELRAH 158

Query: 180 ENKVKKIQKDTFKGMNALHVLEMSANPLDNNGIEPGAFEGVT-VFHIRIAEAKLTSVPKG 238
           EN++ K++K TF G+N + V+E+  NPL ++GIE GAF+G+  + +IRIA+  +TS+P+G
Sbjct: 159 ENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQG 218

Query: 239 LPPTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIENGSLANIPRVREIHLEN 298
           LPP+L ELHLD NKIS V+    K    L +LGL  N I+ ++NGSLAN P +RE+HL+N
Sbjct: 219 LPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDN 278

Query: 299 NKLKKIPSGLPELKYLQIIFLHSNSIARVGVNDFCPTVPKMKKSLYSAISLFNNPVKYWE 358
           NKL ++P GL E KY+Q+++LH+N+I+ VG +DFCP     KK+ YS +SLF+NPV+YWE
Sbjct: 279 NKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWE 338

Query: 359 MQPATFRCVLSRMSVQLGNF 378
           +QP+TFRCV  R ++QLGN+
Sbjct: 339 IQPSTFRCVYVRSAIQLGNY 358


>gi|4503271 decorin isoform a preproprotein [Homo sapiens]
          Length = 359

 Score =  369 bits (947), Expect = e-102
 Identities = 191/380 (50%), Positives = 256/380 (67%), Gaps = 24/380 (6%)

Query: 1   MKEYVLLLFLALCS-AKPFFSPSHIALKNMMLKDMEDTDDDDDDDDDDDDDDEDNSLFPT 59
           MK  ++LL LA  S A PF       L + ML+D       +  DD D            
Sbjct: 1   MKATIILLLLAQVSWAGPF---QQRGLFDFMLEDEASGIGPEVPDDRD------------ 45

Query: 60  REPRSHFFPFDLFPMCPFGCQCYSRVVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKE 119
                  F   L P+CPF CQC+ RVV CSDLGL  VP ++P DT +LDLQNNKI EIK+
Sbjct: 46  -------FEPSLGPVCPFRCQCHLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKD 98

Query: 120 NDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLNLPKSLAELRIH 179
            DFK L +L+ LIL NNK++K+ P AF    KL RLYLS NQL E+P  +PK+L ELR H
Sbjct: 99  GDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKELPEKMPKTLQELRAH 158

Query: 180 ENKVKKIQKDTFKGMNALHVLEMSANPLDNNGIEPGAFEGVT-VFHIRIAEAKLTSVPKG 238
           EN++ K++K TF G+N + V+E+  NPL ++GIE GAF+G+  + +IRIA+  +TS+P+G
Sbjct: 159 ENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQG 218

Query: 239 LPPTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIENGSLANIPRVREIHLEN 298
           LPP+L ELHLD NKIS V+    K    L +LGL  N I+ ++NGSLAN P +RE+HL+N
Sbjct: 219 LPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDN 278

Query: 299 NKLKKIPSGLPELKYLQIIFLHSNSIARVGVNDFCPTVPKMKKSLYSAISLFNNPVKYWE 358
           NKL ++P GL E KY+Q+++LH+N+I+ VG +DFCP     KK+ YS +SLF+NPV+YWE
Sbjct: 279 NKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWE 338

Query: 359 MQPATFRCVLSRMSVQLGNF 378
           +QP+TFRCV  R ++QLGN+
Sbjct: 339 IQPSTFRCVYVRSAIQLGNY 358


>gi|19743848 decorin isoform b precursor [Homo sapiens]
          Length = 250

 Score =  212 bits (539), Expect = 5e-55
 Identities = 98/180 (54%), Positives = 137/180 (76%), Gaps = 1/180 (0%)

Query: 200 LEMSANPLDNNGIEPGAFEGVT-VFHIRIAEAKLTSVPKGLPPTLLELHLDYNKISTVEL 258
           LE+  NPL ++GIE GAF+G+  + +IRIA+  +TS+P+GLPP+L ELHLD NKIS V+ 
Sbjct: 70  LELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDA 129

Query: 259 EDFKRYKELQRLGLGNNKITDIENGSLANIPRVREIHLENNKLKKIPSGLPELKYLQIIF 318
              K    L +LGL  N I+ ++NGSLAN P +RE+HL+NNKL ++P GL E KY+Q+++
Sbjct: 130 ASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVY 189

Query: 319 LHSNSIARVGVNDFCPTVPKMKKSLYSAISLFNNPVKYWEMQPATFRCVLSRMSVQLGNF 378
           LH+N+I+ VG +DFCP     KK+ YS +SLF+NPV+YWE+QP+TFRCV  R ++QLGN+
Sbjct: 190 LHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYVRSAIQLGNY 249



 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 71/262 (27%), Positives = 103/262 (39%), Gaps = 62/262 (23%)

Query: 1   MKEYVLLLFLALCS-AKPFFSPSHIALKNMMLKDMEDTDDDDDDDDDDDDDDEDNSLFPT 59
           MK  ++LL LA  S A PF       L + ML+D       +  DD D            
Sbjct: 1   MKATIILLLLAQVSWAGPF---QQRGLFDFMLEDEASGIGPEVPDDRD------------ 45

Query: 60  REPRSHFFPFDLFPMCPFGCQCYSRVVHCSDL---------------------------- 91
                  F   L P+CPF CQC+ RVV CSDL                            
Sbjct: 46  -------FEPSLGPVCPFRCQCHLRVVQCSDLELGTNPLKSSGIENGAFQGMKKLSYIRI 98

Query: 92  ---GLTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLT 148
               +TS+P  +P     L L  NKI  +     KGL +L  L L+ N ++ +   +   
Sbjct: 99  ADTNITSIPQGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLAN 158

Query: 149 TKKLRRLYLSHNQLSEIPLNLP--KSLAELRIHENKVKKIQKDTF--KGMNALHV----L 200
           T  LR L+L +N+L+ +P  L   K +  + +H N +  +    F   G N        +
Sbjct: 159 TPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGV 218

Query: 201 EMSANPLDNNGIEPGAFEGVTV 222
            + +NP+    I+P  F  V V
Sbjct: 219 SLFSNPVQYWEIQPSTFRCVYV 240


>gi|19743850 decorin isoform c precursor [Homo sapiens]
          Length = 212

 Score =  176 bits (445), Expect = 4e-44
 Identities = 81/155 (52%), Positives = 112/155 (72%), Gaps = 4/155 (2%)

Query: 224 HIRIAEAKLTSVPKGLPPTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIENG 283
           H+R+ +        GLPP+L ELHLD NKIS V+    K    L +LGL  N I+ ++NG
Sbjct: 61  HLRVVQCS----DLGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNG 116

Query: 284 SLANIPRVREIHLENNKLKKIPSGLPELKYLQIIFLHSNSIARVGVNDFCPTVPKMKKSL 343
           SLAN P +RE+HL+NNKL ++P GL E KY+Q+++LH+N+I+ VG +DFCP     KK+ 
Sbjct: 117 SLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKAS 176

Query: 344 YSAISLFNNPVKYWEMQPATFRCVLSRMSVQLGNF 378
           YS +SLF+NPV+YWE+QP+TFRCV  R ++QLGN+
Sbjct: 177 YSGVSLFSNPVQYWEIQPSTFRCVYVRSAIQLGNY 211



 Score = 79.7 bits (195), Expect = 4e-15
 Identities = 70/231 (30%), Positives = 99/231 (42%), Gaps = 38/231 (16%)

Query: 1   MKEYVLLLFLALCS-AKPFFSPSHIALKNMMLKDMEDTDDDDDDDDDDDDDDEDNSLFPT 59
           MK  ++LL LA  S A PF       L + ML+D       +  DD D            
Sbjct: 1   MKATIILLLLAQVSWAGPF---QQRGLFDFMLEDEASGIGPEVPDDRD------------ 45

Query: 60  REPRSHFFPFDLFPMCPFGCQCYSRVVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKE 119
                  F   L P+CPF CQC+ RVV CSDLGL       P     L L  NKI  +  
Sbjct: 46  -------FEPSLGPVCPFRCQCHLRVVQCSDLGL-------PPSLTELHLDGNKISRVDA 91

Query: 120 NDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLNLP--KSLAELR 177
              KGL +L  L L+ N ++ +   +   T  LR L+L +N+L+ +P  L   K +  + 
Sbjct: 92  ASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVY 151

Query: 178 IHENKVKKIQKDTF--KGMNALHV----LEMSANPLDNNGIEPGAFEGVTV 222
           +H N +  +    F   G N        + + +NP+    I+P  F  V V
Sbjct: 152 LHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYV 202


>gi|4505047 lumican precursor [Homo sapiens]
          Length = 338

 Score =  147 bits (371), Expect = 2e-35
 Identities = 99/312 (31%), Positives = 169/312 (54%), Gaps = 18/312 (5%)

Query: 67  FPFDLF----PMCPFGCQC---YSRVVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKE 119
           FP  ++    P C   C C   Y   ++C +L L SVP  +P   + L L+NN+I  I E
Sbjct: 25  FPLSIYGQSSPNCAPECNCPESYPSAMYCDELKLKSVPM-VPPGIKYLYLRNNQIDHIDE 83

Query: 120 NDFKGLTSLYGLILNNNKL--TKIHPKAFLTTKKLRRLYLSHNQLSEIPLNLPKSLAELR 177
             F+ +T L  LIL++N L  +KI  + F   K+L++L+++HN L+E    LPKSL +L+
Sbjct: 84  KAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQ 143

Query: 178 IHENKVKKIQKDTFKGMNALHVLEMSANPLDNNGIEPGAFEGV-TVFHIRIAEAKLTSVP 236
           +  NK+ K+   +F+G+  L  + +  N L  + +   AF+G+ ++ ++ ++  ++  +P
Sbjct: 144 LTHNKITKL--GSFEGLVNLTFIHLQHNRLKEDAVS-AAFKGLKSLEYLDLSFNQIARLP 200

Query: 237 KGLPPTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIE-NGSLANIPRVREIH 295
            GLP +LL L+LD NKIS +  E FKR+  LQ L L +N++ D    G+  N+  + E+ 
Sbjct: 201 SGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELD 260

Query: 296 LENNKLKKIPSGLPELKYLQIIFLHSNSIARVGVNDFCPTVPKMKKSLYSAISLFNNPVK 355
           L  NKLK IP+     + L+  +L  N + +  +  FC  +  +  S    + L  N + 
Sbjct: 261 LSYNKLKNIPT---VNENLENYYLEVNQLEKFDIKSFCKILGPLSYSKIKHLRLDGNRIS 317

Query: 356 YWEMQPATFRCV 367
              + P  + C+
Sbjct: 318 ETSLPPDMYECL 329


>gi|4557543 extracellular matrix protein 2 precursor [Homo sapiens]
          Length = 699

 Score =  140 bits (352), Expect = 2e-33
 Identities = 96/303 (31%), Positives = 155/303 (51%), Gaps = 11/303 (3%)

Query: 32  KDMEDTDDDDDDDDDDDDDDEDNSLF--PTREPRSHFFPFDLFPMCPFGCQCYSRVVHCS 89
           +D E+  ++ ++D++D++D     +F  P+R P     P       P GC    R + C 
Sbjct: 273 EDEEEEGEEGEEDEEDEEDPVRGDMFRMPSRSPLPA--PPRGTLRLPSGCSLSYRTISCI 330

Query: 90  DLGLTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTK--IHPKAFL 147
           +  LT +P         L+L  N I  I +  F GL +L  L L+ N +T   I PKAF 
Sbjct: 331 NAMLTQIPPLTAPQITSLELTGNSIASIPDEAFNGLPNLERLDLSKNNITSSGIGPKAFK 390

Query: 148 TTKKLRRLYLSHNQLSEIPLNLPKSLAELRIHENKVKKIQKDTFKGMNALHVLEMSANPL 207
             KKL RL +  N L +IP  LP +L EL+++EN ++ I +++   +N L  LE+  N L
Sbjct: 391 LLKKLMRLNMDGNNLIQIPSQLPSTLEELKVNENNLQAIDEESLSDLNQLVTLELEGNNL 450

Query: 208 DNNGIEPGAFEGV-TVFHIRIAEAKLTSVPKGLPPTLLELHLDYNKISTVELEDFKRYKE 266
               + P AF+ + ++ ++R+ + K   +P+GLP ++ EL+L+ N+I  +    F   ++
Sbjct: 451 SEANVNPLAFKPLKSLAYLRLGKNKFRIIPQGLPGSIEELYLENNQIEEITEICFNHTRK 510

Query: 267 LQRLGLGNNKITDIENGSLA--NIPRVREIHLENNKLKKIPSGLPELKYLQIIFLHSNSI 324
           +  + L  NKI +     LA  N   +  I L  NKL  +PS LP  K L  + L  N I
Sbjct: 511 INVIVLRYNKIEENRIAPLAWINQENLESIDLSYNKLYHVPSYLP--KSLLHLVLLGNQI 568

Query: 325 ARV 327
            R+
Sbjct: 569 ERI 571



 Score =  108 bits (269), Expect = 1e-23
 Identities = 85/290 (29%), Positives = 138/290 (47%), Gaps = 8/290 (2%)

Query: 93  LTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTK--IHPKAFLTTK 150
           L  +P+ +P     L +  N ++ I E     L  L  L L  N L++  ++P AF   K
Sbjct: 405 LIQIPSQLPSTLEELKVNENNLQAIDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLK 464

Query: 151 KLRRLYLSHNQLSEIPLNLPKSLAELRIHENKVKKIQKDTFKGMNALHVLEMSANPLDNN 210
            L  L L  N+   IP  LP S+ EL +  N++++I +  F     ++V+ +  N ++ N
Sbjct: 465 SLAYLRLGKNKFRIIPQGLPGSIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEEN 524

Query: 211 GIEPGAF-EGVTVFHIRIAEAKLTSVPKGLPPTLLELHLDYNKISTVELEDFKRYKE-LQ 268
            I P A+     +  I ++  KL  VP  LP +LL L L  N+I  +    F   +  L+
Sbjct: 525 RIAPLAWINQENLESIDLSYNKLYHVPSYLPKSLLHLVLLGNQIERIPGYVFGHMEPGLE 584

Query: 269 RLGLGNNKITDIENGSLA---NIPRVREIHLENNKLKKIPSGLPELKYLQIIFLHSNSIA 325
            L L  NK+ D     ++       +RE+ L++N LK IP G+ E+K L  + L++N I 
Sbjct: 585 YLYLSFNKLADDGMDRVSFYGAYHSLRELFLDHNDLKSIPPGIQEMKALHFLRLNNNKIR 644

Query: 326 RVGVNDFCPTVPKMKKSLYSAISLFNNPVKYWEMQPATFRCVLSRMSVQL 375
            +   + C    +   S    + L NN +K  E+   TF C+ S  S+ L
Sbjct: 645 NILPEEIC-NAEEDDDSNLEHLHLENNYIKIREIPSYTFSCIRSYSSIVL 693


>gi|4826876 osteomodulin [Homo sapiens]
          Length = 421

 Score =  139 bits (349), Expect = 6e-33
 Identities = 95/324 (29%), Positives = 168/324 (51%), Gaps = 18/324 (5%)

Query: 42  DDDDDDDDDDEDNSLFPTREPRSHFFPFDLFPM-CPFGCQC---YSRVVHCSDLGLTSVP 97
           D+D D + DD+  + FP R+   +  PF  + + C   C C   +   ++C +  L ++P
Sbjct: 28  DEDYDQEPDDDYQTGFPFRQNVDYGVPFHQYTLGCVSECFCPTNFPSSMYCDNRKLKTIP 87

Query: 98  TNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLT--KIHPKAFLTTKKLRRL 155
            NIP   + L LQ N+I+ +  N F   T L  + L++NK+   KI    F     L +L
Sbjct: 88  -NIPMHIQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQL 146

Query: 156 YLSHNQLSEIPLNLPKSLAELRIHENKVKKIQKDTFKGMNALHVLEMSANPLDNNGIEPG 215
           +L HN L E P  LPKSL  L +  N++ K+Q +   G+  L +L++  N L ++ ++  
Sbjct: 147 HLEHNNLEEFPFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDK 206

Query: 216 AFEGV-TVFHIRIAEAKLTSVPKGLPPTLLELHLDYNKISTVELEDFKRYKELQRLGLGN 274
            F  +  +  + +   +L S+P GLP +L+ L L+ N IS++  + F +  +L  L + +
Sbjct: 207 IFAKMEKLMQLNLCSNRLESMPPGLPSSLMYLSLENNSISSIPEKYFDKLPKLHTLRMSH 266

Query: 275 NKITDIENGSLANIPRVREIHLENNKLKK---IPSGLPELKYLQIIFLHSNSIARVGVND 331
           NK+ DI   ++ N+P + E+ + +NKLK+   IP  L  L      +L +N I ++ +  
Sbjct: 267 NKLQDIPY-NIFNLPNIVELSVGHNKLKQAFYIPRNLEHL------YLQNNEIEKMNLTV 319

Query: 332 FCPTVPKMKKSLYSAISLFNNPVK 355
            CP++  +     + I +  N +K
Sbjct: 320 MCPSIDPLHYHHLTYIRVDQNKLK 343


>gi|41349454 proline arginine-rich end leucine-rich repeat protein
           precursor [Homo sapiens]
          Length = 382

 Score =  137 bits (344), Expect = 2e-32
 Identities = 90/293 (30%), Positives = 145/293 (49%), Gaps = 15/293 (5%)

Query: 48  DDDDEDNSLFPTREPRSHFFPFDLFPMCPFGCQC---YSRVVHCSDLGLTSVPTNIPFDT 104
           D+  E   L P   P     P  +FP CP  C C   +   ++C    L  VP  IP   
Sbjct: 50  DEPAEPTDLPPPLPPG----PPSIFPDCPRECYCPPDFPSALYCDSRNLRKVPV-IPPRI 104

Query: 105 RMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSE 164
             L LQNN I E+    F+  T L  + L+NN++ KI  +       L  LY+  NQL E
Sbjct: 105 HYLYLQNNFITELPVESFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLEE 164

Query: 165 IPLNLPKSLAELRIHENKVKKIQKDTFKGMNALHVLEMSANPLDNNGIEPGAFEGV-TVF 223
           +P  LP++L +LR+ +N + +I    F  +  L +L++  N L +   +P  F G+  + 
Sbjct: 165 VPSALPRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLM 224

Query: 224 HIRIAEAKLTSVPKGLPPTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKITD--IE 281
            + +A   L  +P  +P  + +L+LD NKI T+    FK +  L  + L  NK+TD  + 
Sbjct: 225 QLNLAHNILRKMPPRVPTAIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLP 284

Query: 282 NGSLANIPRVREIHLENNKLKKIPSGLPELKYLQIIFLHSNSIARVGVNDFCP 334
             S  NI  +  +HL +N++  +P+    L++L   +L++NSI ++     CP
Sbjct: 285 KNSF-NISNLLVLHLSHNRISSVPAINNRLEHL---YLNNNSIEKINGTQICP 333


>gi|4506041 proline arginine-rich end leucine-rich repeat protein
           precursor [Homo sapiens]
          Length = 382

 Score =  137 bits (344), Expect = 2e-32
 Identities = 90/293 (30%), Positives = 145/293 (49%), Gaps = 15/293 (5%)

Query: 48  DDDDEDNSLFPTREPRSHFFPFDLFPMCPFGCQC---YSRVVHCSDLGLTSVPTNIPFDT 104
           D+  E   L P   P     P  +FP CP  C C   +   ++C    L  VP  IP   
Sbjct: 50  DEPAEPTDLPPPLPPG----PPSIFPDCPRECYCPPDFPSALYCDSRNLRKVPV-IPPRI 104

Query: 105 RMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSE 164
             L LQNN I E+    F+  T L  + L+NN++ KI  +       L  LY+  NQL E
Sbjct: 105 HYLYLQNNFITELPVESFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLEE 164

Query: 165 IPLNLPKSLAELRIHENKVKKIQKDTFKGMNALHVLEMSANPLDNNGIEPGAFEGV-TVF 223
           +P  LP++L +LR+ +N + +I    F  +  L +L++  N L +   +P  F G+  + 
Sbjct: 165 VPSALPRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLM 224

Query: 224 HIRIAEAKLTSVPKGLPPTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKITD--IE 281
            + +A   L  +P  +P  + +L+LD NKI T+    FK +  L  + L  NK+TD  + 
Sbjct: 225 QLNLAHNILRKMPPRVPTAIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLP 284

Query: 282 NGSLANIPRVREIHLENNKLKKIPSGLPELKYLQIIFLHSNSIARVGVNDFCP 334
             S  NI  +  +HL +N++  +P+    L++L   +L++NSI ++     CP
Sbjct: 285 KNSF-NISNLLVLHLSHNRISSVPAINNRLEHL---YLNNNSIEKINGTQICP 333


>gi|34577057 fibronectin leucine rich transmembrane protein 1 [Homo
           sapiens]
          Length = 674

 Score =  135 bits (340), Expect = 6e-32
 Identities = 92/281 (32%), Positives = 143/281 (50%), Gaps = 33/281 (11%)

Query: 75  CPFGCQCYSRVVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGLILN 134
           CP  C+C +  ++C+D GLTS+P +IP D   L LQNN+I                   N
Sbjct: 54  CPSVCRCDNGFIYCNDRGLTSIPADIPDDATTLYLQNNQI-------------------N 94

Query: 135 NNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLNLPKSLAELRIHENKVKKIQKDTFKGM 194
           N  +    P+   T   ++ +YL  N L E P+NLP+SL EL + +N V+ I +D+   +
Sbjct: 95  NAGI----PQDLKTKVNVQVIYLYENDLDEFPINLPRSLRELHLQDNNVRTIARDSLARI 150

Query: 195 NALHVLEMSANPLDNNGIEPGAF-EGVTVFHIRIAEAKLTSVPKGLPPTLLELHLDYNKI 253
             L  L +  N +    IE  AF +   +  + ++   L+S+P GLP TL EL LD N+I
Sbjct: 151 PLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLEELRLDDNRI 210

Query: 254 STVELEDFKRYKELQRLGLGNNKITD--IENGSLANIPRVREIHLENNKLKKIPSGLPEL 311
           ST+ L  FK    L+RL L  N + +  I + + + +  + E+ L  N L   P  LP  
Sbjct: 211 STIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAAPPLNLPS- 269

Query: 312 KYLQIIFLHSNSIARVGVNDFCPTVPKMKKSLYSAISLFNN 352
            +LQ ++L  N+I+ +  N    T+ KM++     + L NN
Sbjct: 270 AHLQKLYLQDNAISHIPYN----TLAKMRE--LERLDLSNN 304


>gi|5901992 keratocan [Homo sapiens]
          Length = 352

 Score =  129 bits (324), Expect = 4e-30
 Identities = 86/268 (32%), Positives = 138/268 (51%), Gaps = 11/268 (4%)

Query: 75  CPFGCQC---YSRVVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGL 131
           CP  C C   +   ++C + GL  +P  IP     L LQNN I+ I E  F+  T L  +
Sbjct: 42  CPMECFCPPSFPTALYCENRGLKEIPA-IPSRIWYLYLQNNLIETIPEKPFENATQLRWI 100

Query: 132 ILNNNKLTK--IHPKAFLTTKKLRRLYLSHNQLSEIPLNLPKSLAELRIHENKVKKIQKD 189
            LN NK+T   I   A    KKL  L+L  N+L E+P  LP+SL +L++  NKV +I + 
Sbjct: 101 NLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQG 160

Query: 190 TFKGMNALHVLEMSANPLDNNGIEPGAFEGV-TVFHIRIAEAKLTSVPKGLPPTLLELHL 248
           TF  +  L +L++  N L +N  +   F+G+  +  + +A+  L ++P  LP   ++L L
Sbjct: 161 TFSNLENLTLLDLQNNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFL 220

Query: 249 DYNKISTVELEDFKRYKELQRLGLGNNKITDIENGSLA-NIPRVREIHLENNKLKKIPSG 307
           D N I  +    F    ++  L L +NK++D    S   ++  + ++ L +N+L K+P  
Sbjct: 221 DNNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPSRGFDVSSILDLQLSHNQLTKVPRI 280

Query: 308 LPELKYLQIIFLHSNSIARVGVNDFCPT 335
              L++L    L  N I  V V+  CP+
Sbjct: 281 SAHLQHLH---LDHNKIKSVNVSVICPS 305


>gi|38202222 fibronectin leucine rich transmembrane protein 3
           precursor [Homo sapiens]
          Length = 649

 Score =  125 bits (313), Expect = 8e-29
 Identities = 86/261 (32%), Positives = 123/261 (47%), Gaps = 27/261 (10%)

Query: 75  CPFGCQCYSRVVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGLILN 134
           CP  C+C +  ++C+D  LTS+PT IP D   L LQNN+I                   N
Sbjct: 31  CPSVCRCDAGFIYCNDRFLTSIPTGIPEDATTLYLQNNQI-------------------N 71

Query: 135 NNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLNLPKSLAELRIHENKVKKIQKDTFKGM 194
           N  +    P       K+ R+YL HN L E P NLPK + EL + EN ++ I  D+   +
Sbjct: 72  NAGI----PSDLKNLLKVERIYLYHNSLDEFPTNLPKYVKELHLQENNIRTITYDSLSKI 127

Query: 195 NALHVLEMSANPLDNNGIEPGAFEGVTVFHIR-IAEAKLTSVPKGLPPTLLELHLDYNKI 253
             L  L +  N +    IE GAF       +  ++   L+++P GLP T+ EL LD N+I
Sbjct: 128 PYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIEELRLDDNRI 187

Query: 254 STVELEDFKRYKELQRLGLGNNKITDIENGS--LANIPRVREIHLENNKLKKIPSGLPEL 311
           ST+     +    L+RL L  N + +   G     N+  + E+ L  N L   P  LP  
Sbjct: 188 STISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNSLTAAPVNLPGT 247

Query: 312 KYLQIIFLHSNSIARVGVNDF 332
             L+ ++L  N I RV  N F
Sbjct: 248 N-LRKLYLQDNHINRVPPNAF 267


>gi|7019383 fibronectin leucine rich transmembrane protein 3
           precursor [Homo sapiens]
          Length = 649

 Score =  125 bits (313), Expect = 8e-29
 Identities = 86/261 (32%), Positives = 123/261 (47%), Gaps = 27/261 (10%)

Query: 75  CPFGCQCYSRVVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGLILN 134
           CP  C+C +  ++C+D  LTS+PT IP D   L LQNN+I                   N
Sbjct: 31  CPSVCRCDAGFIYCNDRFLTSIPTGIPEDATTLYLQNNQI-------------------N 71

Query: 135 NNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLNLPKSLAELRIHENKVKKIQKDTFKGM 194
           N  +    P       K+ R+YL HN L E P NLPK + EL + EN ++ I  D+   +
Sbjct: 72  NAGI----PSDLKNLLKVERIYLYHNSLDEFPTNLPKYVKELHLQENNIRTITYDSLSKI 127

Query: 195 NALHVLEMSANPLDNNGIEPGAFEGVTVFHIR-IAEAKLTSVPKGLPPTLLELHLDYNKI 253
             L  L +  N +    IE GAF       +  ++   L+++P GLP T+ EL LD N+I
Sbjct: 128 PYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIEELRLDDNRI 187

Query: 254 STVELEDFKRYKELQRLGLGNNKITDIENGS--LANIPRVREIHLENNKLKKIPSGLPEL 311
           ST+     +    L+RL L  N + +   G     N+  + E+ L  N L   P  LP  
Sbjct: 188 STISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNSLTAAPVNLPGT 247

Query: 312 KYLQIIFLHSNSIARVGVNDF 332
             L+ ++L  N I RV  N F
Sbjct: 248 N-LRKLYLQDNHINRVPPNAF 267


>gi|226342933 podocan-like 1 isoform 2 [Homo sapiens]
          Length = 510

 Score =  124 bits (310), Expect = 2e-28
 Identities = 87/260 (33%), Positives = 139/260 (53%), Gaps = 10/260 (3%)

Query: 75  CPFGCQCYSRV--VHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGLI 132
           CP  C C  RV  V C  L L   P NI    + L LQNN+++E+  N+   L+ L  L 
Sbjct: 44  CPLRCSC-PRVDTVDCDGLDLRVFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTLN 102

Query: 133 LNNNKLTK--IHPKAFLTTKKLRRLYLSHNQLSEIPLNLPKSLAELRIHENKVKKIQKDT 190
           L+NN ++   +  +AF +  +L+ L ++HN+LS  P  LP+SL    +  N+V +I   T
Sbjct: 103 LHNNLISSEGLPDEAFESLTQLQHLCVAHNKLSVAPQFLPRSLRVADLAANQVMEIFPLT 162

Query: 191 FKGMNALHVLEMSANPLDNNGIEPGAFEG-VTVFHIRIAEAKLTSVPKGLPPTLLELHLD 249
           F    AL  + +  N L N G+ P AF G   +  + ++  +L+ +P  LPP+L  LHL 
Sbjct: 163 FGEKPALRSVYLHNNQLSNAGLPPDAFRGSEAIATLSLSNNQLSYLPPSLPPSLERLHLQ 222

Query: 250 YNKISTVELEDFKRYKELQRLGLGNNKITD--IENGSLANIPRVREIHLENNKLKKIPSG 307
            N IS V      R  +L+ L L +N++TD  ++  + + +  +  + L +N+L  +P+G
Sbjct: 223 NNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAG 282

Query: 308 LPELKYLQIIFLHSNSIARV 327
           LP  + L I+ L  N I +V
Sbjct: 283 LP--RTLAILHLGRNRIRQV 300



 Score = 97.8 bits (242), Expect = 1e-20
 Identities = 66/230 (28%), Positives = 110/230 (47%), Gaps = 6/230 (2%)

Query: 93  LTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTK--IHPKAFLTTK 150
           L+ +P ++P     L LQNN I ++        T L  L L +N+LT   +    F    
Sbjct: 205 LSYLPPSLPPSLERLHLQNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLH 264

Query: 151 KLRRLYLSHNQLSEIPLNLPKSLAELRIHENKVKKIQKDTFKGMNALHVLEMSANPLDNN 210
            L  L LSHNQL+ +P  LP++LA L +  N++++++     G   L  L +  N L ++
Sbjct: 265 SLEYLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSS 324

Query: 211 GIEPGAFEGVTVFH-IRIAEAKLTSVPKGLPPTLLELHLDYNKISTVELEDFKRYKELQR 269
           G+  GA   +   H + +    L  VP  LP  L  L L +N ++ +   D      L  
Sbjct: 325 GLPAGALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTE 384

Query: 270 LGLGNNKITD--IENGSLANIPRVREIHLENNKLKKIPSGLPE-LKYLQI 316
           L L  N++    + + +   +  +R + L  N+L ++P GLP  L+ LQ+
Sbjct: 385 LNLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQL 434



 Score = 71.6 bits (174), Expect = 1e-12
 Identities = 47/165 (28%), Positives = 78/165 (47%), Gaps = 3/165 (1%)

Query: 86  VHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLT--KIHP 143
           +H    GL  VP  +P   R L L +N +  +   D      L  L L  N+L   ++H 
Sbjct: 340 LHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHH 399

Query: 144 KAFLTTKKLRRLYLSHNQLSEIPLNLPKSLAELRIHENKVKKIQKDTFKGMNALHVLEMS 203
           +AF   + LR L L+ NQL+ +P+ LP  L  L++  N+++ ++ +   G++ L  L ++
Sbjct: 400 RAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRELSLA 459

Query: 204 ANPLDNNGIEPGAFEGVTVFHIRIAEAKLTSVPKGLPPTLLELHL 248
            N L    I PG +  +    +R      T VP+  P   L  H+
Sbjct: 460 HNRLRVGDIGPGTWHELQALQVRHRLVSHT-VPRAPPSPCLPCHV 503


>gi|226342931 podocan-like 1 isoform 1 [Homo sapiens]
          Length = 512

 Score =  124 bits (310), Expect = 2e-28
 Identities = 87/260 (33%), Positives = 139/260 (53%), Gaps = 10/260 (3%)

Query: 75  CPFGCQCYSRV--VHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGLI 132
           CP  C C  RV  V C  L L   P NI    + L LQNN+++E+  N+   L+ L  L 
Sbjct: 46  CPLRCSC-PRVDTVDCDGLDLRVFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTLN 104

Query: 133 LNNNKLTK--IHPKAFLTTKKLRRLYLSHNQLSEIPLNLPKSLAELRIHENKVKKIQKDT 190
           L+NN ++   +  +AF +  +L+ L ++HN+LS  P  LP+SL    +  N+V +I   T
Sbjct: 105 LHNNLISSEGLPDEAFESLTQLQHLCVAHNKLSVAPQFLPRSLRVADLAANQVMEIFPLT 164

Query: 191 FKGMNALHVLEMSANPLDNNGIEPGAFEG-VTVFHIRIAEAKLTSVPKGLPPTLLELHLD 249
           F    AL  + +  N L N G+ P AF G   +  + ++  +L+ +P  LPP+L  LHL 
Sbjct: 165 FGEKPALRSVYLHNNQLSNAGLPPDAFRGSEAIATLSLSNNQLSYLPPSLPPSLERLHLQ 224

Query: 250 YNKISTVELEDFKRYKELQRLGLGNNKITD--IENGSLANIPRVREIHLENNKLKKIPSG 307
            N IS V      R  +L+ L L +N++TD  ++  + + +  +  + L +N+L  +P+G
Sbjct: 225 NNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAG 284

Query: 308 LPELKYLQIIFLHSNSIARV 327
           LP  + L I+ L  N I +V
Sbjct: 285 LP--RTLAILHLGRNRIRQV 302



 Score = 97.8 bits (242), Expect = 1e-20
 Identities = 66/230 (28%), Positives = 110/230 (47%), Gaps = 6/230 (2%)

Query: 93  LTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTK--IHPKAFLTTK 150
           L+ +P ++P     L LQNN I ++        T L  L L +N+LT   +    F    
Sbjct: 207 LSYLPPSLPPSLERLHLQNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLH 266

Query: 151 KLRRLYLSHNQLSEIPLNLPKSLAELRIHENKVKKIQKDTFKGMNALHVLEMSANPLDNN 210
            L  L LSHNQL+ +P  LP++LA L +  N++++++     G   L  L +  N L ++
Sbjct: 267 SLEYLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSS 326

Query: 211 GIEPGAFEGVTVFH-IRIAEAKLTSVPKGLPPTLLELHLDYNKISTVELEDFKRYKELQR 269
           G+  GA   +   H + +    L  VP  LP  L  L L +N ++ +   D      L  
Sbjct: 327 GLPAGALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTE 386

Query: 270 LGLGNNKITD--IENGSLANIPRVREIHLENNKLKKIPSGLPE-LKYLQI 316
           L L  N++    + + +   +  +R + L  N+L ++P GLP  L+ LQ+
Sbjct: 387 LNLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQL 436



 Score = 71.6 bits (174), Expect = 1e-12
 Identities = 47/165 (28%), Positives = 78/165 (47%), Gaps = 3/165 (1%)

Query: 86  VHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLT--KIHP 143
           +H    GL  VP  +P   R L L +N +  +   D      L  L L  N+L   ++H 
Sbjct: 342 LHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHH 401

Query: 144 KAFLTTKKLRRLYLSHNQLSEIPLNLPKSLAELRIHENKVKKIQKDTFKGMNALHVLEMS 203
           +AF   + LR L L+ NQL+ +P+ LP  L  L++  N+++ ++ +   G++ L  L ++
Sbjct: 402 RAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRELSLA 461

Query: 204 ANPLDNNGIEPGAFEGVTVFHIRIAEAKLTSVPKGLPPTLLELHL 248
            N L    I PG +  +    +R      T VP+  P   L  H+
Sbjct: 462 HNRLRVGDIGPGTWHELQALQVRHRLVSHT-VPRAPPSPCLPCHV 505


>gi|71040111 fibromodulin precursor [Homo sapiens]
          Length = 376

 Score =  122 bits (305), Expect = 7e-28
 Identities = 83/290 (28%), Positives = 140/290 (48%), Gaps = 18/290 (6%)

Query: 75  CPFGCQC---YSRVVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGL 131
           CP  C C   +   ++C +  L  +P  +P   + +  QNN+I  I+E  F   T L  +
Sbjct: 76  CPQECDCPPNFPTAMYCDNRNLKYLPF-VPSRMKYVYFQNNQITSIQEGVFDNATGLLWI 134

Query: 132 ILNNNKLT--KIHPKAFLTTKKLRRLYLSHNQLSEIPLNLPKSLAELRIHENKVKKIQKD 189
            L+ N++T  K+  K F   + L RLYL HN L+ +P  LP+SL EL +  N++ ++  +
Sbjct: 135 ALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPLPRSLRELHLDHNQISRVPNN 194

Query: 190 TFKGMNALHVLEMSANPLDNNGIEPGAFEGVTVFHIRIAEAKLTSVPKGLPPTLLELHLD 249
             +G+  L  L +  N +   G        + +  + ++   L  VP GLP  L +L+++
Sbjct: 195 ALEGLENLTALYLQHNEIQEVGSSMRGLRSLIL--LDLSYNHLRKVPDGLPSALEQLYME 252

Query: 250 YNKISTVELEDFKRYKELQRLGLGNNKITDIENGSLA----NIPRVREIHLENNKLKKIP 305
           +N + TV    F+   +L  + L +N +T   N  LA    N   + E+ L  N+L+KIP
Sbjct: 253 HNNVYTVPDSYFRGAPKLLYVRLSHNSLT---NNGLASNTFNSSSLLELDLSYNQLQKIP 309

Query: 306 SGLPELKYLQIIFLHSNSIARVGVNDFCPTVPKMKKSLYSAISLFNNPVK 355
              P    L+ ++L  N I    ++ FC  V  +  S    + L  N +K
Sbjct: 310 ---PVNTNLENLYLQGNRINEFSISSFCTVVDVVNFSKLQVLRLDGNEIK 356


>gi|7019381 fibronectin leucine rich transmembrane protein 2 [Homo
           sapiens]
          Length = 660

 Score =  117 bits (292), Expect = 2e-26
 Identities = 76/262 (29%), Positives = 130/262 (49%), Gaps = 29/262 (11%)

Query: 75  CPFGCQCYSRVVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGLILN 134
           CP  C+C    V+C++  LTSVP  IP                     +G+T LY   L+
Sbjct: 36  CPSVCRCDRNFVYCNERSLTSVPLGIP---------------------EGVTVLY---LH 71

Query: 135 NNKLTKI-HPKAFLTTKKLRRLYLSHNQLSEIPLNLPKSLAELRIHENKVKKIQKDTFKG 193
           NN++     P      + +  +YL  NQL E P+NLPK++  L + EN ++ I +     
Sbjct: 72  NNQINNAGFPAELHNVQSVHTVYLYGNQLDEFPMNLPKNVRVLHLQENNIQTISRAALAQ 131

Query: 194 MNALHVLEMSANPLDNNGIEPGAF-EGVTVFHIRIAEAKLTSVPKGLPPTLLELHLDYNK 252
           +  L  L +  N +   G+E GAF E +++  + +++  L+SVP GLP  L EL +D N+
Sbjct: 132 LLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGLPVDLQELRVDENR 191

Query: 253 ISTVELEDFKRYKELQRLGLGNNKITD--IENGSLANIPRVREIHLENNKLKKIPSGLPE 310
           I+ +    F+    L+RL +  N +T+  I  G+ +++ +++E  +  N L   P  LP 
Sbjct: 192 IAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPPDLPG 251

Query: 311 LKYLQIIFLHSNSIARVGVNDF 332
              ++ ++L  N I  + +  F
Sbjct: 252 THLIR-LYLQDNQINHIPLTAF 272



 Score =  109 bits (272), Expect = 5e-24
 Identities = 74/233 (31%), Positives = 115/233 (49%), Gaps = 17/233 (7%)

Query: 93  LTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPK--AFLTTK 150
           L   P N+P + R+L LQ N I+ I       L  L  L L++N ++ +  +  AF    
Sbjct: 100 LDEFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAI 159

Query: 151 KLRRLYLSHNQLSEIPLNLPKSLAELRIHENKVKKIQKDTFKGMNALHVLEMSANPLDNN 210
            L+ L+LS N LS +P+ LP  L ELR+ EN++  I    F+ + +L  L +  N L N 
Sbjct: 160 SLKLLFLSKNHLSSVPVGLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNK 219

Query: 211 GIEPGAFEGVT-VFHIRIAEAKLTSVPKGLPPT-LLELHLDYNKISTVELEDFKRYKELQ 268
           GI  G F  +T +    I    L+  P  LP T L+ L+L  N+I+ + L  F   ++L+
Sbjct: 220 GIAEGTFSHLTKLKEFSIVRNSLSHPPPDLPGTHLIRLYLQDNQINHIPLTAFSNLRKLE 279

Query: 269 RLGLGNNKITDIENGSLANIPRVREIHLENNK-------------LKKIPSGL 308
           RL + NN++  +  G   N+  ++++   NN              LK IPS L
Sbjct: 280 RLDISNNQLRMLTQGVFDNLSNLKQLTARNNPWFCDCSIKWVTEWLKYIPSSL 332


>gi|45505137 podocan [Homo sapiens]
          Length = 661

 Score =  113 bits (282), Expect = 3e-25
 Identities = 74/238 (31%), Positives = 120/238 (50%), Gaps = 7/238 (2%)

Query: 93  LTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTK--IHPKAFLTTK 150
           L  VP ++P     L L+NNK+++I    F  L+SL  L L NN LT   +  + F    
Sbjct: 277 LRHVPKHLPPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLS 336

Query: 151 KLRRLYLSHNQLSEIPLNLPKSLAELRIHENKVKKIQKDTFKGMNALHVLEMSANPLDNN 210
            L  L LS N LS +P  LP+SL  L + +N ++ +  +    + +L  L + +N L   
Sbjct: 337 SLEYLDLSSNNLSRVPAGLPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQ 396

Query: 211 GIEPGAFEGVTVFH-IRIAEAKLTSVPKGLPPTLLELHLDYNKISTVELEDFKRYKELQR 269
           GI P AF+G+   H + +    L  VP GLP  +  L + +N+I+ +  EDF     L+ 
Sbjct: 397 GIHPLAFQGLKRLHTVHLYNNALERVPSGLPRRVRTLMILHNQITGIGREDFATTYFLEE 456

Query: 270 LGLGNNKIT--DIENGSLANIPRVREIHLENNKLKKIPSGLPELKYLQIIFLHSNSIA 325
           L L  N+IT   +   +   +  +R + L  N+L  +P GLP  + + ++ +  N +A
Sbjct: 457 LNLSYNRITSPQVHRDAFRKLRLLRSLDLSGNRLHTLPPGLP--RNVHVLKVKRNELA 512



 Score =  109 bits (272), Expect = 5e-24
 Identities = 91/338 (26%), Positives = 150/338 (44%), Gaps = 79/338 (23%)

Query: 75  CPFGCQCYSR-VVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEI---------------- 117
           CP  C C    VV C  + L   P ++P  T  L LQNN++++I                
Sbjct: 116 CPRDCACSQEGVVDCGGIDLREFPGDLPEHTNHLSLQNNQLEKIYPEELSRLHRLETLNL 175

Query: 118 ----------KENDFKGLTSLYGLILNNNKLT---------------------KIHPKAF 146
                      E  F+ LT+L  L L NNKLT                     KI+   F
Sbjct: 176 QNNRLTSRGLPEKAFEHLTNLNYLYLANNKLTLAPRFLPNALISVDFAANYLTKIYGLTF 235

Query: 147 LTTKKLRRLYLSHNQLSE--------------------------IPLNLPKSLAELRIHE 180
                LR +YL +N+L++                          +P +LP +L +L +  
Sbjct: 236 GQKPNLRSVYLHNNKLADAGLPDNMFNGSSNVEVLILSSNFLRHVPKHLPPALYKLHLKN 295

Query: 181 NKVKKIQKDTFKGMNALHVLEMSANPLDNNGIEPGAFEGV-TVFHIRIAEAKLTSVPKGL 239
           NK++KI    F  +++L  L +  N L + G++   F  + ++ ++ ++   L+ VP GL
Sbjct: 296 NKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAGL 355

Query: 240 PPTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKITD--IENGSLANIPRVREIHLE 297
           P +L+ LHL+ N I +V+       + L+ L L +N++ +  I   +   + R+  +HL 
Sbjct: 356 PRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLKRLHTVHLY 415

Query: 298 NNKLKKIPSGLPELKYLQIIFLHSNSIARVGVNDFCPT 335
           NN L+++PSGLP  +   ++ LH N I  +G  DF  T
Sbjct: 416 NNALERVPSGLPR-RVRTLMILH-NQITGIGREDFATT 451



 Score = 92.0 bits (227), Expect = 8e-19
 Identities = 66/221 (29%), Positives = 114/221 (51%), Gaps = 9/221 (4%)

Query: 86  VHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLT--KIHP 143
           VH  +  L  VP+ +P   R L + +N+I  I   DF     L  L L+ N++T  ++H 
Sbjct: 412 VHLYNNALERVPSGLPRRVRTLMILHNQITGIGREDFATTYFLEELNLSYNRITSPQVHR 471

Query: 144 KAFLTTKKLRRLYLSHNQLSEIPLNLPKSLAELRIHENKVKKIQKDTFKGMNALHVLEMS 203
            AF   + LR L LS N+L  +P  LP+++  L++  N++  + +    GM  L  L ++
Sbjct: 472 DAFRKLRLLRSLDLSGNRLHTLPPGLPRNVHVLKVKRNELAALARGALVGMAQLRELYLT 531

Query: 204 ANPLDNNGIEPGAFEGVTVFHIR---IAEAKLTSVPKGLPPTLLELHLDYNKISTVELED 260
           +N L +  + P A+  V + H++   IA  +LT +P+GLP +L  L+L  NKIS V    
Sbjct: 532 SNRLRSRALGPRAW--VDLAHLQLLDIAGNQLTEIPEGLPESLEYLYLQNNKISAVPANA 589

Query: 261 FKRYKELQRLGLGNNKIT--DIENGSLANIPRVREIHLENN 299
           F     L+ + L  NK+    + + +   +  ++ + +E N
Sbjct: 590 FDSTPNLKGIFLRFNKLAVGSVVDSAFRRLKHLQVLDIEGN 630



 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 36/142 (25%), Positives = 67/142 (47%), Gaps = 2/142 (1%)

Query: 93  LTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTK--IHPKAFLTTK 150
           L ++P  +P +  +L ++ N++  +      G+  L  L L +N+L    + P+A++   
Sbjct: 490 LHTLPPGLPRNVHVLKVKRNELAALARGALVGMAQLRELYLTSNRLRSRALGPRAWVDLA 549

Query: 151 KLRRLYLSHNQLSEIPLNLPKSLAELRIHENKVKKIQKDTFKGMNALHVLEMSANPLDNN 210
            L+ L ++ NQL+EIP  LP+SL  L +  NK+  +  + F     L  + +  N L   
Sbjct: 550 HLQLLDIAGNQLTEIPEGLPESLEYLYLQNNKISAVPANAFDSTPNLKGIFLRFNKLAVG 609

Query: 211 GIEPGAFEGVTVFHIRIAEAKL 232
            +   AF  +    +   E  L
Sbjct: 610 SVVDSAFRRLKHLQVLDIEGNL 631


>gi|157694513 leucine-rich repeat-containing G protein-coupled
           receptor 4 [Homo sapiens]
          Length = 951

 Score =  111 bits (277), Expect = 1e-24
 Identities = 90/291 (30%), Positives = 131/291 (45%), Gaps = 38/291 (13%)

Query: 73  PMCPFGCQCYS-RVVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGL 131
           P+C   C C   R V CS  GLT+VP  +   T+ LD+  N I ++ E+ FK    L  L
Sbjct: 27  PLCAAPCSCDGDRRVDCSGKGLTAVPEGLSAFTQALDISMNNITQLPEDAFKNFPFLEEL 86

Query: 132 ILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLNLPKSLAELRIHENKVKKIQKDTF 191
            L  N L+ IHPKA    K+L+ L L +NQL  +P                      +  
Sbjct: 87  QLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVP---------------------SEAI 125

Query: 192 KGMNALHVLEMSANPLDNNGIEPGAFEG-VTVFHIRIAEAKLTSV---PKGLPPTLLELH 247
           +G++AL  L + AN +    +   +FEG V + H+ + +  LT V   P    PTL  L 
Sbjct: 126 RGLSALQSLRLDANHI--TSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQALT 183

Query: 248 LDYNKISTVELEDFKRYKELQRLGLGNNKITDIENGSLANIPRVREIHLENNKLKKIPSG 307
           L  NKIS++    F     L  L L NNKI  +       +  +  + L  N L + P  
Sbjct: 184 LALNKISSIPDFAFTNLSSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGEFPQA 243

Query: 308 LPELKYLQIIFLHSNSIARV--GVNDFCPTVPKMKKSLYSAISLFNNPVKY 356
           +  L  L+ +  HSNSI+ +  G  D  P        L   I L++NP+ +
Sbjct: 244 IKALPSLKELGFHSNSISVIPDGAFDGNP--------LLRTIHLYDNPLSF 286



 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 28/75 (37%), Positives = 43/75 (57%)

Query: 107 LDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIP 166
           + LQ N+I +IKE  F+GL SL  L L+ N + +IH +AF T   +  L +S N+L+  P
Sbjct: 370 ISLQRNQIYQIKEGTFQGLISLRILDLSRNLIHEIHSRAFATLGPITNLDVSFNELTSFP 429

Query: 167 LNLPKSLAELRIHEN 181
                 L +L++  N
Sbjct: 430 TEGLNGLNQLKLVGN 444



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 33/115 (28%), Positives = 62/115 (53%), Gaps = 4/115 (3%)

Query: 124 GLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIP-LNLPKSLAELRIHENK 182
           G   L  L L   K++ I        K LR L LS+N + ++P  N   +L E+ +  N+
Sbjct: 317 GTVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDLPSFNGCHALEEISLQRNQ 376

Query: 183 VKKIQKDTFKGMNALHVLEMSANPLDNNGIEPGAFEGV-TVFHIRIAEAKLTSVP 236
           + +I++ TF+G+ +L +L++S N +  + I   AF  +  + ++ ++  +LTS P
Sbjct: 377 IYQIKEGTFQGLISLRILDLSRNLI--HEIHSRAFATLGPITNLDVSFNELTSFP 429


>gi|109809759 leucine rich repeat transmembrane neuronal 3 [Homo
           sapiens]
          Length = 581

 Score =  108 bits (269), Expect = 1e-23
 Identities = 85/294 (28%), Positives = 139/294 (47%), Gaps = 51/294 (17%)

Query: 75  CPFGCQCYSRVVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGLILN 134
           CP GC+C  ++V+C    L  +P++I      L L+ N ++++K N FKGL  L  L L+
Sbjct: 34  CPKGCRCEGKMVYCESQKLQEIPSSISAGCLGLSLRYNSLQKLKYNQFKGLNQLTWLYLD 93

Query: 135 NNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLNLPKSLAELRIHENKVKKIQKDTFKGM 194
           +N ++ I   AF   ++L+ L LS N++S   LN                    +TF+ +
Sbjct: 94  HNHISNIDENAFNGIRRLKELILSSNRISYF-LN--------------------NTFRPV 132

Query: 195 NALHVLEMSANPLDNNGIEPGAFEGVTVFHIRIAEAKLTSVPKGLPPTLLELHLDYNKIS 254
             L  L++S N L + G E   F G+                      LL LHL  N + 
Sbjct: 133 TNLRNLDLSYNQLHSLGSE--QFRGLR--------------------KLLSLHLRSNSLR 170

Query: 255 TVELEDFKRYKELQRLGLGNNKITDIENGSLANIPRVREIHLENNKLKKIPSGL-PELKY 313
           T+ +  F+  + L+ L LG N+I  +     A + R++E+HLE+N+  K+   L P L  
Sbjct: 171 TIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVS 230

Query: 314 LQIIFLHSNSIARVGVNDFCPTVPKMKKSLYSAISLFNNPVKYWEMQPATFRCV 367
           LQ ++L  N I+ +G      T+     SL   + L  N ++ +   P+ F+CV
Sbjct: 231 LQNLYLQWNKISVIG-----QTMSWTWSSL-QRLDLSGNEIEAFS-GPSVFQCV 277


>gi|54607118 leucine-rich repeats and immunoglobulin-like domains 1
           [Homo sapiens]
          Length = 1093

 Score =  108 bits (269), Expect = 1e-23
 Identities = 82/288 (28%), Positives = 143/288 (49%), Gaps = 20/288 (6%)

Query: 75  CPFGCQCYSRVVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGLILN 134
           C   C C    + C   GL ++P ++P  TR L+L  NK+ EI    F+ L +L  + LN
Sbjct: 41  CAAACTCAGDSLDCGGRGLAALPGDLPSWTRSLNLSYNKLSEIDPAGFEDLPNLQEVYLN 100

Query: 135 NNKLTKIHPKAFLTTKKLRRLYLSHNQLSEI---PLNLPKSLAELRIHENKVKKIQKDTF 191
           NN+LT + P     +  +  L+L HN++  +    L    SL  L +  N + +++   F
Sbjct: 101 NNELTAV-PSLGAASSHVVSLFLQHNKIRSVEGSQLKAYLSLEVLDLSLNNITEVRNTCF 159

Query: 192 KGMNALHVLEMSANPLDNNGIEPGAFEGV--TVFHIRIAEAKLTSVPKGL--PPTLLELH 247
                +  L ++ N +    +E GAF+G+  ++  +R+++ ++T +P      P L +L 
Sbjct: 160 PHGPPIKELNLAGNRIGT--LELGAFDGLSRSLLTLRLSKNRITQLPVRAFKLPRLTQLD 217

Query: 248 LDYNKISTVELEDFKRYKELQRLGLGNNKITDIENGSLANIPRVREIHLENNKLKKIPSG 307
           L+ N+I  +E   F+    L+ L L  N I+ + +G+   + ++  +HLE N L ++ SG
Sbjct: 218 LNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSG 277

Query: 308 -LPELKYLQIIFLHSNSIARVGVN--DFCPTVPKMKKSLYSAISLFNN 352
            L  L  L  + L +NSIAR+      FC       + L+  +  FNN
Sbjct: 278 SLYGLTALHQLHLSNNSIARIHRKGWSFC-------QKLHELVLSFNN 318



 Score = 82.8 bits (203), Expect = 5e-16
 Identities = 59/199 (29%), Positives = 96/199 (48%), Gaps = 26/199 (13%)

Query: 106 MLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHN---QL 162
           +L L+ N + E+      GLT+L+ L L+NN + +IH K +   +KL  L LS N   +L
Sbjct: 263 VLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRL 322

Query: 163 SEIPLNLPKSLAELRIHENKVKKIQKDTFKGMNALHVLEMSANPLDNNGIE--PGAFEGV 220
            E  L    SL+ LR+  N +  I +  FKG+ +L VL++  N +    IE   GAF G+
Sbjct: 323 DEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGT-IEDTSGAFSGL 381

Query: 221 TVFHIRIAEAKLTSVPKGLPPTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDI 280
                                +L +L L  NKI +V    F   + L+ L LG N I  +
Sbjct: 382 --------------------DSLSKLTLFGNKIKSVAKRAFSGLEGLEHLNLGGNAIRSV 421

Query: 281 ENGSLANIPRVREIHLENN 299
           +  +   +  ++E+H+ ++
Sbjct: 422 QFDAFVKMKNLKELHISSD 440



 Score = 80.5 bits (197), Expect = 2e-15
 Identities = 70/259 (27%), Positives = 128/259 (49%), Gaps = 15/259 (5%)

Query: 106 MLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFL-TTKKLRRLYLSHNQLSE 164
           +LDL  N I E++   F     +  L L  N++  +   AF   ++ L  L LS N++++
Sbjct: 143 VLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRSLLTLRLSKNRITQ 202

Query: 165 IPLN---LPKSLAELRIHENKVKKIQKDTFKGMNALHVLEMSANPLDNNGIEPGAFEGVT 221
           +P+    LP+ L +L ++ N+++ I+  TF+G+N+L VL++  N +    +  GAF G++
Sbjct: 203 LPVRAFKLPR-LTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISK--LTDGAFWGLS 259

Query: 222 VFHIRIAEAK-LTSVPKGLP---PTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKI 277
             H+   E   L  V  G       L +LHL  N I+ +  + +   ++L  L L  N +
Sbjct: 260 KMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNL 319

Query: 278 TDIENGSLANIPRVREIHLENNKLKKIPSG-LPELKYLQIIFLHSNSIARVGVNDFCPTV 336
           T ++  SLA +  +  + L +N +  I  G    L+ L+++ L  N I+   + D     
Sbjct: 320 TRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGT-IEDTSGAF 378

Query: 337 PKMKKSLYSAISLFNNPVK 355
             +     S ++LF N +K
Sbjct: 379 SGLDS--LSKLTLFGNKIK 395


>gi|153251229 chondroadherin precursor [Homo sapiens]
          Length = 359

 Score =  107 bits (267), Expect = 2e-23
 Identities = 73/269 (27%), Positives = 130/269 (48%), Gaps = 37/269 (13%)

Query: 75  CPFGCQCYSRVVH--CSDLGLTSVPTNIPFDTRMLDLQNN-------------------- 112
           CP  C C+S + H  C  +GL  +P  +   T++L+LQ N                    
Sbjct: 23  CPQNCHCHSDLQHVICDKVGLQKIP-KVSEKTKLLNLQRNNFPVLAANSFRAMPNLVSLH 81

Query: 113 ----KIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLN 168
               +I+E+    F+GL  L  L L++N +  +   AF    +L  LYL HN+++E+P  
Sbjct: 82  LQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVTELPRG 141

Query: 169 LPKSLAE---LRIHENKVKKIQKDTFKGMNALHVLEMSANPLDNNGIEPGAFEGV-TVFH 224
           L   L     L+++ NK+++++   F+G   L  L +S N L  + ++PGA + V  +  
Sbjct: 142 LLSPLVNLFILQLNNNKIRELRAGAFQGAKDLRWLYLSENAL--SSLQPGALDDVENLAK 199

Query: 225 IRIAEAKLTSVPKGLPPTLL---ELHLDYNKISTVELEDFKRY-KELQRLGLGNNKITDI 280
             +   +L+S P      L    EL L +N + ++    F+ + + L+ L L N  +   
Sbjct: 200 FHVDRNQLSSYPSAALSKLRVVEELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTNLEKF 259

Query: 281 ENGSLANIPRVREIHLENNKLKKIPSGLP 309
            +G+   +  ++ +HLENN+L ++PS  P
Sbjct: 260 SDGAFLGVTTLKHVHLENNRLNQLPSNFP 288


>gi|188528675 slit homolog 1 [Homo sapiens]
          Length = 1534

 Score =  103 bits (258), Expect = 2e-22
 Identities = 90/352 (25%), Positives = 153/352 (43%), Gaps = 94/352 (26%)

Query: 75  CPFGCQCYSRVVHCSDLGLTSVPTNIPFDT------------------------RMLDLQ 110
           CP  C C + +V C   GLT++P N+P                           R +DL 
Sbjct: 282 CPAMCTCSNGIVDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLS 341

Query: 111 NNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLNL- 169
           NN+I EI  + F+GL SL  L+L  NK+T +    F     L+ L L+ N+++ I  +  
Sbjct: 342 NNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAF 401

Query: 170 --PKSLAELRIHENKVKKIQKDTFKGMNA---LHVLE---------------MSANPLDN 209
              ++L+ L +++NK++ + K TF  + A   LH+ +               +  NP++ 
Sbjct: 402 QDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFICDCNLKWLADFLRTNPIET 461

Query: 210 NGIE------------------------------PGAFE---------GVTVFH------ 224
           +G                                PG  +          V   H      
Sbjct: 462 SGARCASPRRLANKRIGQIKSKKFRCSAKEQYFIPGTEDYQLNSECNSDVVCPHKCRCEA 521

Query: 225 --IRIAEAKLTSVPKGLPPTLLELHLDYNKISTVELED-FKRYKELQRLGLGNNKITDIE 281
             +  +  KLT +P+ +P +  EL L+ N+IS +E    FK+   L+++ L NNK+++IE
Sbjct: 522 NVVECSSLKLTKIPERIPQSTAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIE 581

Query: 282 NGSLANIPRVREIHLENNKLKKIPSGL-PELKYLQIIFLHSNSIARVGVNDF 332
           +G+      V E+HL  N+L+ I SG+   L  L+ + L +N I+ +  + F
Sbjct: 582 DGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSF 633



 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 85/335 (25%), Positives = 140/335 (41%), Gaps = 84/335 (25%)

Query: 74  MCPFGCQCYSRVVHCSDLGLTSVPTNIPFDT-------------------------RMLD 108
           +CP  C+C + VV CS L LT +P  IP  T                         + ++
Sbjct: 512 VCPHKCRCEANVVECSSLKLTKIPERIPQSTAELRLNNNEISILEATGMFKKLTHLKKIN 571

Query: 109 LQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLN 168
           L NNK+ EI++  F+G  S+  L L  N+L  I    F     LR L L +N++S I  +
Sbjct: 572 LSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHND 631

Query: 169 LPKSLAELRI---HENKVKKIQK---DTFKGMNALHVLE--------------------- 201
               L  +R+   ++N++  +     DT + ++ L++L                      
Sbjct: 632 SFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLANPFNCNCQLAWLGGWLRKRKI 691

Query: 202 MSANPLDNNG-----------------IEPGAFEGVTVFH-------------IRIAEAK 231
           ++ NP   N                   E G  EG  +               +R +   
Sbjct: 692 VTGNPRCQNPDFLRQIPLQDVAFPDFRCEEGQEEGGCLPRPQCPQECACLDTVVRCSNKH 751

Query: 232 LTSVPKGLPPTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIENGSLANIPRV 291
           L ++PKG+P  + EL+LD N+ + V       +K LQ + L NNKI+ + N S  N+ ++
Sbjct: 752 LRALPKGIPKNVTELYLDGNQFTLVP-GQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQL 810

Query: 292 REIHLENNKLKKIPS-GLPELKYLQIIFLHSNSIA 325
             + L  N L+ IP      L+ L+++ LH N I+
Sbjct: 811 TTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDIS 845



 Score = 92.0 bits (227), Expect = 8e-19
 Identities = 63/206 (30%), Positives = 96/206 (46%), Gaps = 25/206 (12%)

Query: 75  CPFGCQCYSRVVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGLILN 134
           CP  C C    V C   GL ++P NIP +T  L+L  N I  I +NDF GL  L  L L 
Sbjct: 34  CPALCTCTGTTVDCHGTGLQAIPKNIPRNTERLELNGNNITRIHKNDFAGLKQLRVLQLM 93

Query: 135 NNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLNL---PKSLAELRIHENKVKKIQKDTF 191
            N++  +   AF   K+L RL L+ NQL  +P  L    ++L+ L + EN ++ I +  F
Sbjct: 94  ENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAF 153

Query: 192 KGMNALHVLEMSANPLDNNGIEPGAFEGVTVFHIRIAEAKLTSVPKGLPPTLLELHLDYN 251
           +G   L  L++  N +  + IE GAF  +    +                    L L+ N
Sbjct: 154 RGATDLKNLQLDKNQI--SCIEEGAFRALRGLEV--------------------LTLNNN 191

Query: 252 KISTVELEDFKRYKELQRLGLGNNKI 277
            I+T+ +  F    +L+   L +N +
Sbjct: 192 NITTIPVSSFNHMPKLRTFRLHSNHL 217



 Score = 79.3 bits (194), Expect = 5e-15
 Identities = 73/288 (25%), Positives = 132/288 (45%), Gaps = 46/288 (15%)

Query: 107 LDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIP 166
           LDL  N I+ I    F+G T L  L L+ N+++ I   AF   + L  L L++N ++ IP
Sbjct: 138 LDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIP 197

Query: 167 LN----LPKSLAELRIHENKVK-----------KIQKDTF---------KGMNALHVLEM 202
           ++    +PK L   R+H N +              Q+ T            +  L+V E+
Sbjct: 198 VSSFNHMPK-LRTFRLHSNHLFCDCHLAWLSQWLRQRPTIGLFTQCSGPASLRGLNVAEV 256

Query: 203 SANPLDNNG-----------IEPGAFEGVTVFHIRIAEAK---LTSVPKGLPPTLLELHL 248
             +    +G           +  G+   +      I + +   LT++P  LP T+ E+ L
Sbjct: 257 QKSEFSCSGQGEAGRVPTCTLSSGSCPAMCTCSNGIVDCRGKGLTAIPANLPETMTEIRL 316

Query: 249 DYNKISTVELEDFKRYKELQRLGLGNNKITDIENGSLANIPRVREIHLENNKLKKIPSGL 308
           + N I ++    F  Y++L+R+ L NN+I +I   +   +  +  + L  NK+  +P G+
Sbjct: 317 ELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGV 376

Query: 309 -PELKYLQIIFLHSNSIARVGVNDFCPTVPKMKKSLYSAISLFNNPVK 355
              L  LQ++ L++N I     N   P   +  ++L S +SL++N ++
Sbjct: 377 FGGLYTLQLLLLNANKI-----NCIRPDAFQDLQNL-SLLSLYDNKIQ 418



 Score = 69.7 bits (169), Expect = 4e-12
 Identities = 48/168 (28%), Positives = 83/168 (49%), Gaps = 7/168 (4%)

Query: 162 LSEIPLNLPKSLAELRIHENKVKKIQKDTFKGMNALHVLEMSANPLDNNGIEPGAFEGVT 221
           L  IP N+P++   L ++ N + +I K+ F G+  L VL++  N +    +E GAF+ + 
Sbjct: 52  LQAIPKNIPRNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQI--GAVERGAFDDMK 109

Query: 222 VFH-IRIAEAKLTSVPKGL---PPTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKI 277
               +R+   +L  +P+ L      L  L L  N I  +  + F+   +L+ L L  N+I
Sbjct: 110 ELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQI 169

Query: 278 TDIENGSLANIPRVREIHLENNKLKKIP-SGLPELKYLQIIFLHSNSI 324
           + IE G+   +  +  + L NN +  IP S    +  L+   LHSN +
Sbjct: 170 SCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217



 Score = 60.1 bits (144), Expect = 3e-09
 Identities = 44/158 (27%), Positives = 63/158 (39%), Gaps = 44/158 (27%)

Query: 73  PMCPFGCQCYSRVVHCSDLGLTSVPTNIPFDT-----------------------RMLDL 109
           P CP  C C   VV CS+  L ++P  IP +                        +++DL
Sbjct: 732 PQCPQECACLDTVVRCSNKHLRALPKGIPKNVTELYLDGNQFTLVPGQLSTFKYLQLVDL 791

Query: 110 QNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLNL 169
            NNKI  +  + F  ++ L  LIL+ N L  I P AF   + LR L L            
Sbjct: 792 SNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSL------------ 839

Query: 170 PKSLAELRIHENKVKKIQKDTFKGMNALHVLEMSANPL 207
                    H N +  +Q+  F  + +L  L + ANPL
Sbjct: 840 ---------HGNDISTLQEGIFADVTSLSHLAIGANPL 868



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 24/100 (24%), Positives = 53/100 (53%), Gaps = 9/100 (9%)

Query: 232 LTSVPKGLPPTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIENGSLANIPRV 291
           L ++PK +P     L L+ N I+ +   DF   K+L+ L L  N+I  +E G+  ++  +
Sbjct: 52  LQAIPKNIPRNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKEL 111

Query: 292 REIHLENNKLKKIPSGLPELKYLQIIFLHSNSIARVGVND 331
             + L  N+L  +P         +++F ++ +++R+ +++
Sbjct: 112 ERLRLNRNQLHMLP---------ELLFQNNQALSRLDLSE 142


>gi|198041768 synleurin [Homo sapiens]
          Length = 622

 Score =  103 bits (257), Expect = 3e-22
 Identities = 91/328 (27%), Positives = 148/328 (45%), Gaps = 52/328 (15%)

Query: 75  CPFGCQ-CYSRVVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGLIL 133
           C   CQ C  R ++C +LGL+S+P N P  T  L L  N I  I E++  GL SL  L L
Sbjct: 32  CSSVCQLCTGRQINCRNLGLSSIPKNFPESTVFLYLTGNNISYINESELTGLHSLVALYL 91

Query: 134 NNNKLTKIHPKAFLTTK------------------------KLRRLYLSHNQLSEIP--- 166
           +N+ +  ++PKAF+  +                         LR LYL +NQ+S +P   
Sbjct: 92  DNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLDPGIFKGLLNLRNLYLQYNQVSFVPRGV 151

Query: 167 LNLPKSLAELRIHENKVKKIQKDTFKGMNALHVLEMSANPLDNNGIEPGAFEGV-TVFHI 225
            N   S+  L +  N++  +   TF GM AL +L++S N +    I    F+ +  +  +
Sbjct: 152 FNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNNILR--ISESGFQHLENLACL 209

Query: 226 RIAEAKLTSVPKG---LPPTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIEN 282
            +    LT VP     +  +L  L L +N I  ++   FK    L+ L L N++I ++  
Sbjct: 210 YLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQPFAFKGLANLEYLLLKNSRIRNVTR 269

Query: 283 GSLANIPRVREIHLENNKLKKIPSG----LPELKYL-----QIIFLHSNSIARVGV---- 329
              + I  ++ + L +N L+ + S     L  L YL     +II + +++   +G     
Sbjct: 270 DGFSGINNLKHLILSHNDLENLNSDTFSLLKNLIYLKLDRNRIISIDNDTFENMGASLKI 329

Query: 330 -----NDFCPTVPKMKKSLYSAISLFNN 352
                N+     P++ K L S I L  N
Sbjct: 330 LNLSFNNLTALHPRVLKPLSSLIHLQAN 357


>gi|205277468 leucine rich repeat containing 15 isoform a [Homo
           sapiens]
          Length = 587

 Score =  102 bits (253), Expect = 7e-22
 Identities = 82/291 (28%), Positives = 139/291 (47%), Gaps = 35/291 (12%)

Query: 75  CPFGCQCY-SRVVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGLIL 133
           CP  C C  +  V C+   + +VPT +P++   L + N  I E+ E+ F  +++L  L +
Sbjct: 31  CPSECTCSRASQVECTGARIVAVPTPLPWNAMSLQILNTHITELNESPFLNISALIALRI 90

Query: 134 NNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLNLPK---SLAELRIHENKVKKIQKDT 190
             N+L++I P AF     LR L L++N+L  +P+ L +   SL  L +  N++ +IQ   
Sbjct: 91  EKNELSRITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPAH 150

Query: 191 FKGMNALHVLEMSANPLDNNGIEPGAFE---GVTVFH----------------------I 225
           F   + L  L++  N L+   I  GAF+   G+T  +                      +
Sbjct: 151 FSQCSNLKELQLHGNHLEY--IPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVL 208

Query: 226 RIAEAKLTSVPKGLPPTLL---ELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIEN 282
           R+ E +LT +P G    L+   EL L  N+I  +    F     LQRL L NN I+ +  
Sbjct: 209 RLYENRLTDIPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLPP 268

Query: 283 GSLANIPRVREIHLENNKLKKIPSGL-PELKYLQIIFLHSNSIARVGVNDF 332
                +P++  + L  N LK++  G+   +  L+ ++L+ N I+ +  N F
Sbjct: 269 SIFMQLPQLNRLTLFGNSLKELSLGIFGPMPNLRELWLYDNHISSLPDNVF 319



 Score = 86.7 bits (213), Expect = 3e-17
 Identities = 61/231 (26%), Positives = 104/231 (45%), Gaps = 49/231 (21%)

Query: 105 RMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSE 164
           ++L L  N++ +I    F GL +L  L L  N++  + P  F     L+RLYLS+N +S+
Sbjct: 206 QVLRLYENRLTDIPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQ 265

Query: 165 IP----LNLPK-----------------------SLAELRIHENKVKKIQKDTFKGMNAL 197
           +P    + LP+                       +L EL +++N +  +  + F  +  L
Sbjct: 266 LPPSIFMQLPQLNRLTLFGNSLKELSLGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQL 325

Query: 198 HVLEMSANPLDNNGIEPGAFEGVTVFHIRIAEAKLTSVPKGLPPTLLELHLDYNKISTVE 257
            VL +S N +  + I PGAF G+T                     L EL L  N +  ++
Sbjct: 326 QVLILSRNQI--SFISPGAFNGLT--------------------ELRELSLHTNALQDLD 363

Query: 258 LEDFKRYKELQRLGLGNNKITDIENGSLANIPRVREIHLENNKLKKIPSGL 308
              F+    LQ + L NN++  +     AN+  +  I L+NN+L+ +P G+
Sbjct: 364 GNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQLQNNQLENLPLGI 414



 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 25/82 (30%), Positives = 43/82 (52%), Gaps = 3/82 (3%)

Query: 103 DTRMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQL 162
           + R L L  N ++++  N F+ L +L  + L NN+L ++    F     L  + L +NQL
Sbjct: 348 ELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQLQNNQL 407

Query: 163 SEIPLNL---PKSLAELRIHEN 181
             +PL +      L ELR+++N
Sbjct: 408 ENLPLGIFDHLGKLCELRLYDN 429


>gi|18677767 leucine rich repeat containing 15 isoform b [Homo
           sapiens]
          Length = 581

 Score =  102 bits (253), Expect = 7e-22
 Identities = 82/291 (28%), Positives = 139/291 (47%), Gaps = 35/291 (12%)

Query: 75  CPFGCQCY-SRVVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGLIL 133
           CP  C C  +  V C+   + +VPT +P++   L + N  I E+ E+ F  +++L  L +
Sbjct: 25  CPSECTCSRASQVECTGARIVAVPTPLPWNAMSLQILNTHITELNESPFLNISALIALRI 84

Query: 134 NNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLNLPK---SLAELRIHENKVKKIQKDT 190
             N+L++I P AF     LR L L++N+L  +P+ L +   SL  L +  N++ +IQ   
Sbjct: 85  EKNELSRITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPAH 144

Query: 191 FKGMNALHVLEMSANPLDNNGIEPGAFE---GVTVFH----------------------I 225
           F   + L  L++  N L+   I  GAF+   G+T  +                      +
Sbjct: 145 FSQCSNLKELQLHGNHLEY--IPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVL 202

Query: 226 RIAEAKLTSVPKGLPPTLL---ELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIEN 282
           R+ E +LT +P G    L+   EL L  N+I  +    F     LQRL L NN I+ +  
Sbjct: 203 RLYENRLTDIPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLPP 262

Query: 283 GSLANIPRVREIHLENNKLKKIPSGL-PELKYLQIIFLHSNSIARVGVNDF 332
                +P++  + L  N LK++  G+   +  L+ ++L+ N I+ +  N F
Sbjct: 263 SIFMQLPQLNRLTLFGNSLKELSLGIFGPMPNLRELWLYDNHISSLPDNVF 313



 Score = 86.7 bits (213), Expect = 3e-17
 Identities = 61/231 (26%), Positives = 104/231 (45%), Gaps = 49/231 (21%)

Query: 105 RMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSE 164
           ++L L  N++ +I    F GL +L  L L  N++  + P  F     L+RLYLS+N +S+
Sbjct: 200 QVLRLYENRLTDIPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQ 259

Query: 165 IP----LNLPK-----------------------SLAELRIHENKVKKIQKDTFKGMNAL 197
           +P    + LP+                       +L EL +++N +  +  + F  +  L
Sbjct: 260 LPPSIFMQLPQLNRLTLFGNSLKELSLGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQL 319

Query: 198 HVLEMSANPLDNNGIEPGAFEGVTVFHIRIAEAKLTSVPKGLPPTLLELHLDYNKISTVE 257
            VL +S N +  + I PGAF G+T                     L EL L  N +  ++
Sbjct: 320 QVLILSRNQI--SFISPGAFNGLT--------------------ELRELSLHTNALQDLD 357

Query: 258 LEDFKRYKELQRLGLGNNKITDIENGSLANIPRVREIHLENNKLKKIPSGL 308
              F+    LQ + L NN++  +     AN+  +  I L+NN+L+ +P G+
Sbjct: 358 GNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQLQNNQLENLPLGI 408



 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 25/82 (30%), Positives = 43/82 (52%), Gaps = 3/82 (3%)

Query: 103 DTRMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQL 162
           + R L L  N ++++  N F+ L +L  + L NN+L ++    F     L  + L +NQL
Sbjct: 342 ELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQLQNNQL 401

Query: 163 SEIPLNL---PKSLAELRIHEN 181
             +PL +      L ELR+++N
Sbjct: 402 ENLPLGIFDHLGKLCELRLYDN 423


>gi|156139147 leucine rich repeat transmembrane neuronal 4 isoform b
           [Homo sapiens]
          Length = 518

 Score =  101 bits (251), Expect = 1e-21
 Identities = 69/261 (26%), Positives = 124/261 (47%), Gaps = 33/261 (12%)

Query: 75  CPFGCQCYSRVVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGLILN 134
           CP  C+C  ++V+C       +P NI   ++ L L+ N I+++K N F GL  L  L L+
Sbjct: 34  CPKNCRCDGKIVYCESHAFADIPENISGGSQGLSLRFNSIQKLKSNQFAGLNQLIWLYLD 93

Query: 135 NNKLTKIHPKAFLTTKKLRRLYLSHNQLSEI---PLNLPKSLAELRIHENKVKKIQKDTF 191
           +N ++ +   AF   ++L+ L LS N+++ +     +   +L  L +  NK++ +Q + F
Sbjct: 94  HNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQF 153

Query: 192 KGMNALHVLEMSANPLDNNGIEPGAFEGV-TVFHIRIAEAKLTSVPKGLPPTLL---ELH 247
           KG+  L +L + +N L    I    F+    +  + +   +L S+ +     LL   ELH
Sbjct: 154 KGLRKLIILHLRSNSLKTVPIR--VFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELH 211

Query: 248 LDYNKISTVELEDFKR------------------------YKELQRLGLGNNKITDIENG 283
           L++N+ S +    F R                        +  L  L L  N I  IE G
Sbjct: 212 LEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPG 271

Query: 284 SLANIPRVREIHLENNKLKKI 304
           +   +P +++++L++NKL  I
Sbjct: 272 TFKCLPNLQKLNLDSNKLTNI 292



 Score = 62.8 bits (151), Expect = 5e-10
 Identities = 48/173 (27%), Positives = 82/173 (47%), Gaps = 25/173 (14%)

Query: 106 MLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEI 165
           +L L++N +K +    F+   +L  L L  N+L  +   AF    KL+ L+L HNQ S+I
Sbjct: 161 ILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKI 220

Query: 166 PL-NLPK--SLAELRIHENKVKKIQKDTFKGMNALHVLEMSANPLDNNGIEPGAFEGVTV 222
              + P+  +L  + +  N+++ I +      ++LH L++S N  D  GIEPG F+ +  
Sbjct: 221 NFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGN--DIQGIEPGTFKCL-- 276

Query: 223 FHIRIAEAKLTSVPKGLPPTLLELHLDYNKISTVELEDFKRYKELQRLGLGNN 275
                             P L +L+LD NK++ +  E    +  L  + L  N
Sbjct: 277 ------------------PNLQKLNLDSNKLTNISQETVNAWISLISITLSGN 311



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 33/91 (36%), Positives = 54/91 (59%), Gaps = 1/91 (1%)

Query: 243 LLELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIENGSLANIPRVREIHLENNKLK 302
           L+ L+LD+N IS+V+ + F+  + L+ L L +NKIT + N +   +P +R + L  NKL+
Sbjct: 87  LIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQ 146

Query: 303 KIPS-GLPELKYLQIIFLHSNSIARVGVNDF 332
            + S     L+ L I+ L SNS+  V +  F
Sbjct: 147 TLQSEQFKGLRKLIILHLRSNSLKTVPIRVF 177


>gi|197927168 leucine rich repeat transmembrane neuronal 4 isoform a
           [Homo sapiens]
          Length = 590

 Score =  101 bits (251), Expect = 1e-21
 Identities = 69/261 (26%), Positives = 124/261 (47%), Gaps = 33/261 (12%)

Query: 75  CPFGCQCYSRVVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGLILN 134
           CP  C+C  ++V+C       +P NI   ++ L L+ N I+++K N F GL  L  L L+
Sbjct: 34  CPKNCRCDGKIVYCESHAFADIPENISGGSQGLSLRFNSIQKLKSNQFAGLNQLIWLYLD 93

Query: 135 NNKLTKIHPKAFLTTKKLRRLYLSHNQLSEI---PLNLPKSLAELRIHENKVKKIQKDTF 191
           +N ++ +   AF   ++L+ L LS N+++ +     +   +L  L +  NK++ +Q + F
Sbjct: 94  HNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQF 153

Query: 192 KGMNALHVLEMSANPLDNNGIEPGAFEGV-TVFHIRIAEAKLTSVPKGLPPTLL---ELH 247
           KG+  L +L + +N L    I    F+    +  + +   +L S+ +     LL   ELH
Sbjct: 154 KGLRKLIILHLRSNSLKTVPIR--VFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELH 211

Query: 248 LDYNKISTVELEDFKR------------------------YKELQRLGLGNNKITDIENG 283
           L++N+ S +    F R                        +  L  L L  N I  IE G
Sbjct: 212 LEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPG 271

Query: 284 SLANIPRVREIHLENNKLKKI 304
           +   +P +++++L++NKL  I
Sbjct: 272 TFKCLPNLQKLNLDSNKLTNI 292



 Score = 62.8 bits (151), Expect = 5e-10
 Identities = 48/173 (27%), Positives = 82/173 (47%), Gaps = 25/173 (14%)

Query: 106 MLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEI 165
           +L L++N +K +    F+   +L  L L  N+L  +   AF    KL+ L+L HNQ S+I
Sbjct: 161 ILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKI 220

Query: 166 PL-NLPK--SLAELRIHENKVKKIQKDTFKGMNALHVLEMSANPLDNNGIEPGAFEGVTV 222
              + P+  +L  + +  N+++ I +      ++LH L++S N  D  GIEPG F+ +  
Sbjct: 221 NFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGN--DIQGIEPGTFKCL-- 276

Query: 223 FHIRIAEAKLTSVPKGLPPTLLELHLDYNKISTVELEDFKRYKELQRLGLGNN 275
                             P L +L+LD NK++ +  E    +  L  + L  N
Sbjct: 277 ------------------PNLQKLNLDSNKLTNISQETVNAWISLISITLSGN 311



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 33/91 (36%), Positives = 54/91 (59%), Gaps = 1/91 (1%)

Query: 243 LLELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIENGSLANIPRVREIHLENNKLK 302
           L+ L+LD+N IS+V+ + F+  + L+ L L +NKIT + N +   +P +R + L  NKL+
Sbjct: 87  LIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQ 146

Query: 303 KIPS-GLPELKYLQIIFLHSNSIARVGVNDF 332
            + S     L+ L I+ L SNS+  V +  F
Sbjct: 147 TLQSEQFKGLRKLIILHLRSNSLKTVPIRVF 177


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.138    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,842,199
Number of Sequences: 37866
Number of extensions: 699988
Number of successful extensions: 11869
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 384
Number of HSP's successfully gapped in prelim test: 85
Number of HSP's that attempted gapping in prelim test: 5836
Number of HSP's gapped (non-prelim): 2889
length of query: 380
length of database: 18,247,518
effective HSP length: 104
effective length of query: 276
effective length of database: 14,309,454
effective search space: 3949409304
effective search space used: 3949409304
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.