Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 40805104
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40805104 topoisomerase I binding, arginine/serine-rich [Homo
sapiens]
(1045 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40805104 topoisomerase I binding, arginine/serine-rich [Homo ... 2105 0.0
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 99 2e-20
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 91 7e-18
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 89 2e-17
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 89 2e-17
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 85 3e-16
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 83 1e-15
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 81 4e-15
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 81 4e-15
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens] 78 4e-14
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 78 4e-14
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 77 8e-14
gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens] 76 2e-13
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 75 3e-13
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] 75 3e-13
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 74 5e-13
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 74 7e-13
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 72 2e-12
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 72 3e-12
gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo s... 72 4e-12
gi|60097902 filaggrin [Homo sapiens] 71 5e-12
gi|15055543 splicing factor, arginine/serine-rich 2B [Homo sapiens] 71 5e-12
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 70 8e-12
gi|4827046 U2 small nuclear RNA auxiliary factor 1-like 2 [Homo ... 70 1e-11
gi|38488727 arginine/serine-rich coiled-coil 1 [Homo sapiens] 70 1e-11
gi|50962882 G patch domain containing 8 [Homo sapiens] 70 1e-11
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap... 69 2e-11
gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap... 69 2e-11
gi|9945320 cyclin L1 [Homo sapiens] 67 7e-11
gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens] 66 1e-10
>gi|40805104 topoisomerase I binding, arginine/serine-rich [Homo
sapiens]
Length = 1045
Score = 2105 bits (5454), Expect = 0.0
Identities = 1045/1045 (100%), Positives = 1045/1045 (100%)
Query: 1 MGSQPPLGSPLSREEGEAPPPAPASEGRRRSRRVRLRGSCRHRPSFLGCRELAASAPARP 60
MGSQPPLGSPLSREEGEAPPPAPASEGRRRSRRVRLRGSCRHRPSFLGCRELAASAPARP
Sbjct: 1 MGSQPPLGSPLSREEGEAPPPAPASEGRRRSRRVRLRGSCRHRPSFLGCRELAASAPARP 60
Query: 61 APASSEIMASAAKEFKMDNFSPKAGTSKLQQTVPADASPDSKCPICLDRFDNVSYLDRCL 120
APASSEIMASAAKEFKMDNFSPKAGTSKLQQTVPADASPDSKCPICLDRFDNVSYLDRCL
Sbjct: 61 APASSEIMASAAKEFKMDNFSPKAGTSKLQQTVPADASPDSKCPICLDRFDNVSYLDRCL 120
Query: 121 HKFCFRCVQEWSKNKAECPLCKQPFDSIFHSVRAEDDFKEYVLRPSYNGSFVTPDRRFRY 180
HKFCFRCVQEWSKNKAECPLCKQPFDSIFHSVRAEDDFKEYVLRPSYNGSFVTPDRRFRY
Sbjct: 121 HKFCFRCVQEWSKNKAECPLCKQPFDSIFHSVRAEDDFKEYVLRPSYNGSFVTPDRRFRY 180
Query: 181 RTTLTRERNASVYSPSGPVNRRTTTPPDSGVLFEGLGISTRPRDVEIPQFMRQIAVRRPT 240
RTTLTRERNASVYSPSGPVNRRTTTPPDSGVLFEGLGISTRPRDVEIPQFMRQIAVRRPT
Sbjct: 181 RTTLTRERNASVYSPSGPVNRRTTTPPDSGVLFEGLGISTRPRDVEIPQFMRQIAVRRPT 240
Query: 241 TADERSLRKIQEQDIINFRRTLYRAGARVRNIEDGGRYRDISAEFFRRNPACLHRLVPWL 300
TADERSLRKIQEQDIINFRRTLYRAGARVRNIEDGGRYRDISAEFFRRNPACLHRLVPWL
Sbjct: 241 TADERSLRKIQEQDIINFRRTLYRAGARVRNIEDGGRYRDISAEFFRRNPACLHRLVPWL 300
Query: 301 KRELTVLFGAHGSLVNIVQHIIMSNVTRYDLESQAFVSDLRPFLLNRTEHFIHEFISFAR 360
KRELTVLFGAHGSLVNIVQHIIMSNVTRYDLESQAFVSDLRPFLLNRTEHFIHEFISFAR
Sbjct: 301 KRELTVLFGAHGSLVNIVQHIIMSNVTRYDLESQAFVSDLRPFLLNRTEHFIHEFISFAR 360
Query: 361 SPFNMAAFDQHANYDCPAPSYEEGSHSDSSVITISPDEAETQELDINVATVSQAPWDDET 420
SPFNMAAFDQHANYDCPAPSYEEGSHSDSSVITISPDEAETQELDINVATVSQAPWDDET
Sbjct: 361 SPFNMAAFDQHANYDCPAPSYEEGSHSDSSVITISPDEAETQELDINVATVSQAPWDDET 420
Query: 421 PGPSYSSSEQVHVTMSSLLNTSDSSDEELVTGGATSQIQGVQTNDDLNNDSDDSSDNCVI 480
PGPSYSSSEQVHVTMSSLLNTSDSSDEELVTGGATSQIQGVQTNDDLNNDSDDSSDNCVI
Sbjct: 421 PGPSYSSSEQVHVTMSSLLNTSDSSDEELVTGGATSQIQGVQTNDDLNNDSDDSSDNCVI 480
Query: 481 VGFVKPLAERTPELVELSSDSEDLGSYEKMETVKTQEQEQSYSSGDSDVSRCSSPHSVLG 540
VGFVKPLAERTPELVELSSDSEDLGSYEKMETVKTQEQEQSYSSGDSDVSRCSSPHSVLG
Sbjct: 481 VGFVKPLAERTPELVELSSDSEDLGSYEKMETVKTQEQEQSYSSGDSDVSRCSSPHSVLG 540
Query: 541 KDEQINKGHCDSSTRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSS 600
KDEQINKGHCDSSTRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSS
Sbjct: 541 KDEQINKGHCDSSTRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSS 600
Query: 601 DSRSQSRSGHDQKNHRKHHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTL 660
DSRSQSRSGHDQKNHRKHHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTL
Sbjct: 601 DSRSQSRSGHDQKNHRKHHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTL 660
Query: 661 SLSSESTSRSRSRSSDHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRDGYESSY 720
SLSSESTSRSRSRSSDHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRDGYESSY
Sbjct: 661 SLSSESTSRSRSRSSDHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRDGYESSY 720
Query: 721 RRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSERKYYYYERHRSRSLSSNRSRTA 780
RRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSERKYYYYERHRSRSLSSNRSRTA
Sbjct: 721 RRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSERKYYYYERHRSRSLSSNRSRTA 780
Query: 781 STGTDRVRNEKPGGKRKYKTRHLEGTNEVAQPSREFASKAKDSHYQKSSSKLDGNYKNES 840
STGTDRVRNEKPGGKRKYKTRHLEGTNEVAQPSREFASKAKDSHYQKSSSKLDGNYKNES
Sbjct: 781 STGTDRVRNEKPGGKRKYKTRHLEGTNEVAQPSREFASKAKDSHYQKSSSKLDGNYKNES 840
Query: 841 DTFSDSRSSDRETKHKRRKRKTRSLSVEIVYEGKATDTTKHHKKKKKKHKKKHKKHHGDN 900
DTFSDSRSSDRETKHKRRKRKTRSLSVEIVYEGKATDTTKHHKKKKKKHKKKHKKHHGDN
Sbjct: 841 DTFSDSRSSDRETKHKRRKRKTRSLSVEIVYEGKATDTTKHHKKKKKKHKKKHKKHHGDN 900
Query: 901 ASRSPVVITIDSDSDKDSEVKEDTECDNSGPQDPLQNEFLAPSLEPFETKDVVTIEAEFG 960
ASRSPVVITIDSDSDKDSEVKEDTECDNSGPQDPLQNEFLAPSLEPFETKDVVTIEAEFG
Sbjct: 901 ASRSPVVITIDSDSDKDSEVKEDTECDNSGPQDPLQNEFLAPSLEPFETKDVVTIEAEFG 960
Query: 961 VLDKECDIATLSNNLNNANKTVDNIPPLAASVEQTLDVREESTFVSDLENQPSNIVSLQT 1020
VLDKECDIATLSNNLNNANKTVDNIPPLAASVEQTLDVREESTFVSDLENQPSNIVSLQT
Sbjct: 961 VLDKECDIATLSNNLNNANKTVDNIPPLAASVEQTLDVREESTFVSDLENQPSNIVSLQT 1020
Query: 1021 EPSRQLPSPRTSLMSVCLGRDCDMS 1045
EPSRQLPSPRTSLMSVCLGRDCDMS
Sbjct: 1021 EPSRQLPSPRTSLMSVCLGRDCDMS 1045
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 99.4 bits (246), Expect = 2e-20
Identities = 102/341 (29%), Positives = 165/341 (48%), Gaps = 45/341 (13%)
Query: 586 PYNHRHRKRGRSRSSDSRSQSRSGHDQKNHRKHHGKKRMKSK-RSRSRESSRPRGRRDKK 644
P + R R RSRS SRS+SRS H +K+ + K SK RSRSR SR R K
Sbjct: 177 PGSRRRRSYSRSRSH-SRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRS---KS 232
Query: 645 RSRTRDSSWSRRSQTLSLSSESTSRSRSRSSDHGKRRSRSRNRDRYYLRNNYG------- 697
RSR++ S S++ ++ S S E +SRSRS GK RS+S+++ ++NN
Sbjct: 233 RSRSQSRSRSKKEKSRSPSKE---KSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSR 289
Query: 698 --SRYKWEYTYYSRNKDRDGYESSYRRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNN 755
SR+K + SR+++R E +R ++SR S++ S + R +S S+ + + +
Sbjct: 290 SPSRHKSKSKSRSRSQERRVEEE--KRGSVSRGR-SQEKSLRQSRSRSRSKGGSRSRSRS 346
Query: 756 HSERKYYYYERHRSRSLSSNRSRTASTGTDRVRNEKPGGKR-------KYKTRHLEGTNE 808
S+ K R RSR S +RSR+ S R+ K G KR K K + ++
Sbjct: 347 RSKSKDKRKGRKRSREESRSRSRSRSKSE---RSRKRGSKRDSKAGSSKKKKKEDTDRSQ 403
Query: 809 VAQPSREFASKAKDSHYQKSSSKLDGNYKNES-----DTFSDSRSSDRETKHKRRKRKTR 863
PSR + + + H + SS+ +G ++E+ +T S SRS+ + + + ++R
Sbjct: 404 SRSPSRSVSKERE--HAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSR 461
Query: 864 SLSVEIVYEGKATDTTKHHKKKKKKHKKKHKKHHGDNASRS 904
S S A+ T K + + + + + SRS
Sbjct: 462 SKS--------ASKTRSRSKSRSRSASRSPSRSRSRSHSRS 494
Score = 87.8 bits (216), Expect = 5e-17
Identities = 92/327 (28%), Positives = 143/327 (43%), Gaps = 34/327 (10%)
Query: 546 NKGHCDSSTRIKSKKEEK-RSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRS 604
++ S +R +S+ K RS S SS + + S R S + R R +SRS +
Sbjct: 186 SRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKE 245
Query: 605 QSRSGHDQKNHRKHH--GKKRMKSKRSRSRE-----------SSRPRGRRDKKRSRTRDS 651
+SRS +K+ + H GK R KSK + S P + K +SR+R
Sbjct: 246 KSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSR-- 303
Query: 652 SWSRRSQTLSLSSESTSRSRSRSSDHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNK 711
S RR + + S SR RS + R+SRSR+R + R+ SR K + R +
Sbjct: 304 SQERRVE----EEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKR 359
Query: 712 DRDGYESSYRRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSERKYYYYERHRSRS 771
R+ ES R R+ S++ SR+ S + ++ +KK ++R R SRS
Sbjct: 360 SRE--ESRSRSRSRSKSERSRKRGSK----RDSKAGSSKKKKKEDTDRS---QSRSPSRS 410
Query: 772 LSSNRSRTASTGTDRV-RNEKPGGKRKYKTRHLEGTNEVAQPSREFASKAKDSHYQKSSS 830
+S R S + R R E +TR +N ++P+ S+++ KS+S
Sbjct: 411 VSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSR----SKSAS 466
Query: 831 KLDGNYKNESDTFSDSRSSDRETKHKR 857
K K+ S + S S S R H R
Sbjct: 467 KTRSRSKSRSRSASRSPSRSRSRSHSR 493
Score = 80.1 bits (196), Expect = 1e-14
Identities = 86/303 (28%), Positives = 130/303 (42%), Gaps = 31/303 (10%)
Query: 617 KHHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTLSLSSESTSRSRSRSSD 676
K ++R RSRS SR R R +K S SR + S S+S SRSRS S
Sbjct: 176 KPGSRRRRSYSRSRSHSRSRSRSRHSRK-------SRSRSGSSKSSHSKSRSRSRSGSRS 228
Query: 677 HGKRRSRSRNRDRYYLRNNYG-----SRYKWEYTYYSRNKDRDGYESSYRR-----RTLS 726
K RSRS++R R + SR + SR+K +D E + + S
Sbjct: 229 RSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKS 288
Query: 727 RAHYSRQSSSPEFRVQSFSERTNARKKNN----HSERKYYYYERHRSRSLSSNRSRTAST 782
R+ SR S + R +S R K+ + S+ K R RSRS +RSR+ S
Sbjct: 289 RSP-SRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRS- 346
Query: 783 GTDRVRNEKPGGKR-KYKTRHLEGTNEVAQPSREFASKAKDSHYQKSSSKLDGNYKNESD 841
+ ++++ G KR + ++R + ++ SR+ SK +DS S K K E
Sbjct: 347 -RSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSK-RDSKAGSSKKK-----KKEDT 399
Query: 842 TFSDSRSSDRETKHKRRKRKTRSLSVEIVYEGKATDTTKHHKKKKKKHKKKHKKHHGDNA 901
S SRS R +R K+ S E E + T + + + + + K ++
Sbjct: 400 DRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESR 459
Query: 902 SRS 904
SRS
Sbjct: 460 SRS 462
Score = 76.3 bits (186), Expect = 1e-13
Identities = 74/250 (29%), Positives = 113/250 (45%), Gaps = 15/250 (6%)
Query: 514 KTQEQEQSYSSGDSDVSRCSSPHSVLGKDEQINKGHCDSSTRIKSKKEEKRSTSLSSPRN 573
K + + +S+S+G S + ++ + K S +R KSK +S S S R
Sbjct: 252 KEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKS---KSRSRSQERR 308
Query: 574 LNSSVRGD--RVYSPYNHRHRKRGRSRSSD-SRSQSRSGHDQKNHRKHHGKKRMKSKRSR 630
+ RG R S + R RSRS SRS+SRS K+ RK G+KR + + SR
Sbjct: 309 VEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRK--GRKRSREE-SR 365
Query: 631 SRESSRPRGRRDKKRSRTRDS---SWSRRSQTLSLSSESTSRSRSRSSDHGKRRSRSRNR 687
SR SR + R +KR RDS S ++ + + S+S S SRS S + +S S R
Sbjct: 366 SRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQR 425
Query: 688 DRYYLRNNYGSRYKWEYTYYSRNKDRDGYESSYRRRTLSRAHYSRQSSSPEFRVQSFSER 747
+ N G+ + S +K + S R R+ S S+ S + R +S S
Sbjct: 426 EGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSA---SKTRSRSKSRSRSASRS 482
Query: 748 TNARKKNNHS 757
+ + +HS
Sbjct: 483 PSRSRSRSHS 492
Score = 63.9 bits (154), Expect = 7e-10
Identities = 77/309 (24%), Positives = 127/309 (41%), Gaps = 34/309 (11%)
Query: 611 DQKNHRKHHGKKRMKSKRSRSRESSRPRGRR--DKKRSRTRDSSWSRRSQTLSLSSESTS 668
D RK+ G S R + G +K D SRR ++ S S S S
Sbjct: 134 DAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYS-RSRSHS 192
Query: 669 RSRSRSSDHGKRRSRS--------RNRDRYYLRNNYGSRYKWEYTYYSRNKDRDGYESSY 720
RSRSRS K RSRS ++R R+ GSR SR+K R +S
Sbjct: 193 RSRSRSRHSRKSRSRSGSSKSSHSKSRS----RSRSGSR--------SRSKSRSRSQS-- 238
Query: 721 RRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSERKYYYYE---RHRSRSLSSNRS 777
R+ S+ SR S + R +S S + K + +E K + + +SRS S ++S
Sbjct: 239 --RSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKS 296
Query: 778 RTASTGTD---RVRNEKPGGKRKYKTRHLEGTNEVAQPSREFASKAKDSHYQKSSSKLDG 834
++ S RV EK G + +++ ++ + S+++ KS K G
Sbjct: 297 KSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKG 356
Query: 835 NYKNESDTFSDSRSSDRETKHKRRKRKTRSLSVEIVYEGKATDTTKHHKKKKKKHKKKHK 894
++ ++ S SRS + + ++R K R + K DT + + + K +
Sbjct: 357 RKRSREESRSRSRSRSKSERSRKRGSK-RDSKAGSSKKKKKEDTDRSQSRSPSRSVSKER 415
Query: 895 KHHGDNASR 903
+H +S+
Sbjct: 416 EHAKSESSQ 424
Score = 38.5 bits (88), Expect = 0.033
Identities = 59/256 (23%), Positives = 99/256 (38%), Gaps = 45/256 (17%)
Query: 668 SRSRSRSSDHGKRRS----RSRNRDRY---------YLRNNYGSRYKWEYTYYSRNKDRD 714
+R R +G RS R RD+Y + N SR W+ D
Sbjct: 70 ARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQ--------DLK 121
Query: 715 GYESSYRRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSE---RKYYYYE------ 765
Y T + AH R++ S+S+ A +K + +E RK E
Sbjct: 122 DYMRQAGEVTYADAHKGRKNEGV-IEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSR 180
Query: 766 --RHRSRSLSSNRSRTASTGTDRVRNEKPGGKRKYKTRHLEGTNEVAQPSREFASKAKDS 823
R SRS S +RSR+ S + + R+ K+ H + + SR SK++
Sbjct: 181 RRRSYSRSRSHSRSRSRSRHSRKSRSRSGSS----KSSHSKSRSRSRSGSRS-RSKSRSR 235
Query: 824 HYQKSSSKLDGNYKNESDTFSDSRSSDRETKHKRRKRKTRS----LSVEIVYEGKATDTT 879
+S SK + K+ S + SRS R K K ++ + + V + K+ +
Sbjct: 236 SQSRSRSKKE---KSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPS 292
Query: 880 KHHKKKKKKHKKKHKK 895
+H K K + + + ++
Sbjct: 293 RHKSKSKSRSRSQERR 308
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 90.5 bits (223), Expect = 7e-18
Identities = 81/380 (21%), Positives = 154/380 (40%), Gaps = 31/380 (8%)
Query: 557 KSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRSQSRSGHDQKNHR 616
+ ++ EKR T + R DR RHR+R R R + Q+ D++ +
Sbjct: 62 RERRREKRQTERETDRKRERRREKDRHRK--RDRHRERQRDREKERERQTDRERDRQREK 119
Query: 617 KHHGKKRMKSKRSRSRESSRPRGRR---DKKRSRTRDSSWSRRSQTLSLSSESTSRSRSR 673
+ + +K + +R RE R R R+ ++R R RD+ R QT T R+R +
Sbjct: 120 ERNRQK--ERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQK 177
Query: 674 SSDHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRDGYESSYRRRTLSRAHYSRQ 733
+ K R R R+R + N + + R ++R+ + R+R R ++
Sbjct: 178 EREREKNRQERRERERQREKEN-KTEDRHSERGRERERERETETETERKRQTDRERDRQR 236
Query: 734 SSSPEFRVQSFSERTNARKKNNHSERKYYYYERHRSRSLSSNRSRTASTGTDRVRNEKPG 793
+ E Q+ ER + R+ ER ER R R +R + + R +
Sbjct: 237 KTEREREKQAERERASERETERDKER-----ERERDRDRDRDRRQ-------KERERQTD 284
Query: 794 GKRKYKTRHLEGTNEVAQPSREFASKAKDSHYQKSSSKLDGNYKNESDTFSDSRSSDRET 853
KR+ +T T + RE + + + ++ + + + + +T D R +RE
Sbjct: 285 RKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERD-REKERER 343
Query: 854 KHKRRKRKTRSLSVEIVYEGKATDTTKHHKKKKKKHKKKHKKHHGDNASRSPVVITIDSD 913
K KR+ R + + EG+ + +++++ + ++ + D D
Sbjct: 344 KRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERER----------DRD 393
Query: 914 SDKDSEVKEDTECDNSGPQD 933
D+ E + TE D G ++
Sbjct: 394 RDRQKERERQTEKDRDGQRE 413
Score = 79.0 bits (193), Expect = 2e-14
Identities = 71/337 (21%), Positives = 134/337 (39%), Gaps = 23/337 (6%)
Query: 592 RKRGRSRS-SDSRSQSRSGHDQKNHRKHHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRD 650
R+RG ++ D+ R + QK + K++ + + R RE R + R +KR R R+
Sbjct: 38 RRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRH-RKRDRHRE 96
Query: 651 SSWSRRSQTLSLSSESTSRSRSRSSDHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRN 710
R + T R R R + K R+R + R+R R G R + T R
Sbjct: 97 RQRDREKE----RERQTDRERDRQRE--KERNRQKERERETERE--GERGRDRQTDGQRE 148
Query: 711 KDRDGYESSYRRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSERKYYYYERHRSR 770
++R R R R + + + + R R++ E++ +RH R
Sbjct: 149 RERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSER 208
Query: 771 SLSSNRSRTASTGTDRVRNEKPGGKRKYKTRHLEGTNEVAQPSREFASKAKDSHYQKSSS 830
R R T T+R R R+ KT Q RE AS+ + ++
Sbjct: 209 GRERERERETETETERKRQTDRERDRQRKTER----EREKQAERERASERETERDKERER 264
Query: 831 KLDGNYKNESDTFSDSRSSDRETKHKRRKRKTRSLSVEIVYEGKATDTTKHHKKKKKKHK 890
+ D + D + +R+T KR++R R E + + + ++++++++
Sbjct: 265 ERD----RDRDRDRRQKERERQTDRKRQRRTERDRETE-----RKRERQRERERERERNR 315
Query: 891 KKHKKHHGDNASRSPVVITIDSDSDKDSEVKEDTECD 927
K+ ++ + D + +++ + K TE D
Sbjct: 316 KRERERERERERERQRETERDREKERERKRKRQTEMD 352
Score = 77.8 bits (190), Expect = 5e-14
Identities = 88/465 (18%), Positives = 170/465 (36%), Gaps = 45/465 (9%)
Query: 499 SDSEDLGSYEKMETVKTQEQEQSYSSGD--------SDVSRCSSPHSVLGKDEQINKGHC 550
+D +D + E + +E+ Q+ D D R H +D + +
Sbjct: 49 ADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQ 108
Query: 551 DSSTRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRSQSRSGH 610
R + +++E+ R + G+R R+R R R ++ + ++
Sbjct: 109 TDRERDRQREKERNR---QKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDR 165
Query: 611 DQKNHRKHHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTLSLSSESTSRS 670
+++ + + +K + +++R R R R + ++ R S R + + T R
Sbjct: 166 ERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERK 225
Query: 671 RSRSSDHGKRRSRSRNRDRYYLRNNYGSRY----KWEYTYYSRNKDRDGYESSYRRRT-L 725
R + ++R R R++ R R K R++DRD + R+T
Sbjct: 226 RQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDR 285
Query: 726 SRAHYSRQSSSPEFRVQSFSERTNARKKNNHSER-------KYYYYERHRSRSLSSNRSR 778
R + + E + + ER R++N ER + E R R R R
Sbjct: 286 KRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKR 345
Query: 779 TASTGTDRVRNEKPG--GKRKYKTRHLEGTNEVAQPSREFASKAKDSHYQKSSSKLDGNY 836
T DR RN + G G+R+ + Q +RE + +D + +
Sbjct: 346 KRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKER----- 400
Query: 837 KNESDTFSDSRSSDRETKHKRRKRKTRSLSVEIVYEGKATDTTKHHKKKKKKHKKKH-KK 895
E T D R RET+ +R + K R G+ + +K +++ +++ +
Sbjct: 401 --ERQTEKD-RDGQRETEKQREREKDRESE-----RGRERGREREKQKGRERDRERQTDR 452
Query: 896 HHGDNASRSPVVITIDSDSDKDSEVKEDTECDNSG------PQDP 934
G RS + + + + V+ D G P+DP
Sbjct: 453 QAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPTRGIRWKSSPEDP 497
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 89.0 bits (219), Expect = 2e-17
Identities = 85/311 (27%), Positives = 132/311 (42%), Gaps = 7/311 (2%)
Query: 592 RKRGRSRSSDSRSQSRSGHDQKNHRKH-HGKKRMKS-KRSRSRESSRPRGRR-DKKRSRT 648
RK GRSRS +RS+SRS + RK K R +S RSRSR+ R R + KKRS++
Sbjct: 303 RKGGRSRSH-TRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKS 361
Query: 649 RDSSWSRRSQTLSLSSESTSRSRSRSSDHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYS 708
R+ S RS++ S +R + + + K + R + R+R R R K +
Sbjct: 362 RERRKS-RSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKE 420
Query: 709 RNKDRDGYESSYRRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSERKYYYYERHR 768
R KDR+ + R R + H + E ER R K +RK R
Sbjct: 421 REKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTP 480
Query: 769 SRSLSSNRSRTASTGTDRVRNEKPGGKRKYKTRHLEGTNEVAQPSREFASKAKDSHYQKS 828
RS +++R R+ S+ +R R R +T PS +K KD +K
Sbjct: 481 PRSYNASR-RSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNK-KDKKREKE 538
Query: 829 SSKLDGNYKNESDTFSDSRSSDRETKHKRRKRKTRSLSVEIVYEGKATDTTKHHKKKKKK 888
+ + E T S+DR+ K K K T E E ++ + + K +
Sbjct: 539 RDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPR 598
Query: 889 HKKKHKKHHGD 899
++ +H+G+
Sbjct: 599 TEENKIQHNGN 609
Score = 68.9 bits (167), Expect = 2e-11
Identities = 79/317 (24%), Positives = 132/317 (41%), Gaps = 47/317 (14%)
Query: 622 KRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTLSLSSESTSRSRSRSSDHGKRR 681
KR++ +S + P + +R R S +R S++ S S + R RS+S K R
Sbjct: 280 KRVREAQSFISAAIEPESGKSNERKGGRSRSHTR-SKSRSSSKSHSRRKRSQS----KHR 334
Query: 682 SRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRDGYESSYRRRTLSRAHYSRQSSSPEFRV 741
SRS NR R SR KDR +S +++R+ SR +S S
Sbjct: 335 SRSHNRSR------------------SRQKDRRRSKSPHKKRSKSRERRKSRSRS----- 371
Query: 742 QSFSERTNARKKNNHSER---KYYYYERHRSRSLSSNRSRTASTGTDRVRN-EKPGGKRK 797
S +R + R+K ER K ER R + + R + D+ R ++ K K
Sbjct: 372 HSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEK 431
Query: 798 YKTRHLEGTNEVAQPSREFASKAKDSHYQKSSSK-LDGNYKNESDTFSD---------SR 847
+ R E +E + + + K+ +K SK +D K + + + SR
Sbjct: 432 DREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSR 491
Query: 848 SSDRETKHKRRKRKTRSLSVEIVYEGKATDTTK---HHKKKKKKHKKKHKKHHGDNASRS 904
SS RE + +R + +RS + K++ + +KK KK ++K + H + R
Sbjct: 492 SSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKK--REKERDHISERRERE 549
Query: 905 PVVITIDSDSDKDSEVK 921
S +D+D + K
Sbjct: 550 RSTSMRKSSNDRDGKEK 566
Score = 52.0 bits (123), Expect = 3e-06
Identities = 54/227 (23%), Positives = 91/227 (40%), Gaps = 51/227 (22%)
Query: 699 RYKWEYTYYSRNKDRDGYESSYRRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSE 758
R + ++ S + + +S+ R+ SR+H +S S S ++++R+K + S
Sbjct: 281 RVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRS--------SSKSHSRRKRSQS- 331
Query: 759 RKYYYYERHRSRSLSSNRSRTASTGTDRVRNEKPGGKRKYKTRHLEGTNEVAQPSREFAS 818
+HRSRS + +RSR DR R++ P KR SRE
Sbjct: 332 -------KHRSRSHNRSRSRQ----KDRRRSKSPHKKR--------------SKSRERRK 366
Query: 819 KAKDSHYQKSSSKLDGNYKNESDTFSDSRSSDRETKHKRRKRKTRSLSVEIVYEGKATDT 878
SH + K + R +RE + +R K K R GK D
Sbjct: 367 SRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKER---------GKNKDR 417
Query: 879 TKHHKKKKKKHKKKHKKHHGDNASRSPVVITIDSDSDKDSEVKEDTE 925
K +K ++K K+K ++ + + D DK+ E ++D E
Sbjct: 418 DKEREKDREKDKEKDREREREKEH--------EKDRDKEKEKEQDKE 456
Score = 39.7 bits (91), Expect = 0.015
Identities = 35/147 (23%), Positives = 65/147 (44%), Gaps = 23/147 (15%)
Query: 789 NEKPGGKRKYKTRHLEGTNEVAQPSREFASKAKDSHYQKSSSKLDGNYKNESDTFSDSRS 848
NE+ GG+ + TR S+ +S S ++S SK +++ S S SR
Sbjct: 301 NERKGGRSRSHTR-----------SKSRSSSKSHSRRKRSQSK----HRSRSHNRSRSRQ 345
Query: 849 SDR---ETKHKRR-----KRKTRSLSVEIVYEGKATDTTKHHKKKKKKHKKKHKKHHGDN 900
DR ++ HK+R +RK+RS S + K ++ K+K ++K ++ +
Sbjct: 346 KDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKER 405
Query: 901 ASRSPVVITIDSDSDKDSEVKEDTECD 927
D D +++ + ++D E D
Sbjct: 406 EKEKERGKNKDRDKEREKDREKDKEKD 432
Score = 37.7 bits (86), Expect = 0.057
Identities = 33/129 (25%), Positives = 54/129 (41%), Gaps = 24/129 (18%)
Query: 559 KKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSD-------------SRSQ 605
+K +K S + PR+ N+S R S + R R+R RSRSS SRS
Sbjct: 469 EKRKKDKKSRTPPRSYNASRR-----SRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSP 523
Query: 606 SRSGHDQKNHRKHHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTLSLSSE 665
S ++K+ ++ + + +R R R +S +K S RD + SL +
Sbjct: 524 SPRSRNKKDKKREKERDHISERRERERSTSM------RKSSNDRDGKEKLEKNSTSLKEK 577
Query: 666 STSRSRSRS 674
++ S
Sbjct: 578 EHNKEPDSS 586
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 89.0 bits (219), Expect = 2e-17
Identities = 85/311 (27%), Positives = 132/311 (42%), Gaps = 7/311 (2%)
Query: 592 RKRGRSRSSDSRSQSRSGHDQKNHRKH-HGKKRMKS-KRSRSRESSRPRGRR-DKKRSRT 648
RK GRSRS +RS+SRS + RK K R +S RSRSR+ R R + KKRS++
Sbjct: 187 RKGGRSRSH-TRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKS 245
Query: 649 RDSSWSRRSQTLSLSSESTSRSRSRSSDHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYS 708
R+ S RS++ S +R + + + K + R + R+R R R K +
Sbjct: 246 RERRKS-RSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKE 304
Query: 709 RNKDRDGYESSYRRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSERKYYYYERHR 768
R KDR+ + R R + H + E ER R K +RK R
Sbjct: 305 REKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTP 364
Query: 769 SRSLSSNRSRTASTGTDRVRNEKPGGKRKYKTRHLEGTNEVAQPSREFASKAKDSHYQKS 828
RS +++R R+ S+ +R R R +T PS +K KD +K
Sbjct: 365 PRSYNASR-RSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNK-KDKKREKE 422
Query: 829 SSKLDGNYKNESDTFSDSRSSDRETKHKRRKRKTRSLSVEIVYEGKATDTTKHHKKKKKK 888
+ + E T S+DR+ K K K T E E ++ + + K +
Sbjct: 423 RDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPR 482
Query: 889 HKKKHKKHHGD 899
++ +H+G+
Sbjct: 483 TEENKIQHNGN 493
Score = 68.9 bits (167), Expect = 2e-11
Identities = 79/317 (24%), Positives = 132/317 (41%), Gaps = 47/317 (14%)
Query: 622 KRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTLSLSSESTSRSRSRSSDHGKRR 681
KR++ +S + P + +R R S +R S++ S S + R RS+S K R
Sbjct: 164 KRVREAQSFISAAIEPESGKSNERKGGRSRSHTR-SKSRSSSKSHSRRKRSQS----KHR 218
Query: 682 SRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRDGYESSYRRRTLSRAHYSRQSSSPEFRV 741
SRS NR R SR KDR +S +++R+ SR +S S
Sbjct: 219 SRSHNRSR------------------SRQKDRRRSKSPHKKRSKSRERRKSRSRS----- 255
Query: 742 QSFSERTNARKKNNHSER---KYYYYERHRSRSLSSNRSRTASTGTDRVRN-EKPGGKRK 797
S +R + R+K ER K ER R + + R + D+ R ++ K K
Sbjct: 256 HSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEK 315
Query: 798 YKTRHLEGTNEVAQPSREFASKAKDSHYQKSSSK-LDGNYKNESDTFSD---------SR 847
+ R E +E + + + K+ +K SK +D K + + + SR
Sbjct: 316 DREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSR 375
Query: 848 SSDRETKHKRRKRKTRSLSVEIVYEGKATDTTK---HHKKKKKKHKKKHKKHHGDNASRS 904
SS RE + +R + +RS + K++ + +KK KK ++K + H + R
Sbjct: 376 SSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKK--REKERDHISERRERE 433
Query: 905 PVVITIDSDSDKDSEVK 921
S +D+D + K
Sbjct: 434 RSTSMRKSSNDRDGKEK 450
Score = 52.0 bits (123), Expect = 3e-06
Identities = 54/227 (23%), Positives = 91/227 (40%), Gaps = 51/227 (22%)
Query: 699 RYKWEYTYYSRNKDRDGYESSYRRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSE 758
R + ++ S + + +S+ R+ SR+H +S S S ++++R+K + S
Sbjct: 165 RVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRS--------SSKSHSRRKRSQS- 215
Query: 759 RKYYYYERHRSRSLSSNRSRTASTGTDRVRNEKPGGKRKYKTRHLEGTNEVAQPSREFAS 818
+HRSRS + +RSR DR R++ P KR SRE
Sbjct: 216 -------KHRSRSHNRSRSRQ----KDRRRSKSPHKKR--------------SKSRERRK 250
Query: 819 KAKDSHYQKSSSKLDGNYKNESDTFSDSRSSDRETKHKRRKRKTRSLSVEIVYEGKATDT 878
SH + K + R +RE + +R K K R GK D
Sbjct: 251 SRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKER---------GKNKDR 301
Query: 879 TKHHKKKKKKHKKKHKKHHGDNASRSPVVITIDSDSDKDSEVKEDTE 925
K +K ++K K+K ++ + + D DK+ E ++D E
Sbjct: 302 DKEREKDREKDKEKDREREREKEH--------EKDRDKEKEKEQDKE 340
Score = 39.7 bits (91), Expect = 0.015
Identities = 35/147 (23%), Positives = 65/147 (44%), Gaps = 23/147 (15%)
Query: 789 NEKPGGKRKYKTRHLEGTNEVAQPSREFASKAKDSHYQKSSSKLDGNYKNESDTFSDSRS 848
NE+ GG+ + TR S+ +S S ++S SK +++ S S SR
Sbjct: 185 NERKGGRSRSHTR-----------SKSRSSSKSHSRRKRSQSK----HRSRSHNRSRSRQ 229
Query: 849 SDR---ETKHKRR-----KRKTRSLSVEIVYEGKATDTTKHHKKKKKKHKKKHKKHHGDN 900
DR ++ HK+R +RK+RS S + K ++ K+K ++K ++ +
Sbjct: 230 KDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKER 289
Query: 901 ASRSPVVITIDSDSDKDSEVKEDTECD 927
D D +++ + ++D E D
Sbjct: 290 EKEKERGKNKDRDKEREKDREKDKEKD 316
Score = 37.7 bits (86), Expect = 0.057
Identities = 33/129 (25%), Positives = 54/129 (41%), Gaps = 24/129 (18%)
Query: 559 KKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSD-------------SRSQ 605
+K +K S + PR+ N+S R S + R R+R RSRSS SRS
Sbjct: 353 EKRKKDKKSRTPPRSYNASRR-----SRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSP 407
Query: 606 SRSGHDQKNHRKHHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTLSLSSE 665
S ++K+ ++ + + +R R R +S +K S RD + SL +
Sbjct: 408 SPRSRNKKDKKREKERDHISERRERERSTSM------RKSSNDRDGKEKLEKNSTSLKEK 461
Query: 666 STSRSRSRS 674
++ S
Sbjct: 462 EHNKEPDSS 470
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 85.1 bits (209), Expect = 3e-16
Identities = 87/322 (27%), Positives = 134/322 (41%), Gaps = 51/322 (15%)
Query: 590 RHRKRGRSRSS----DSRSQSRSGHDQKNHRKHHGKKRMKSKRSRSRESSR-PRGRRDKK 644
RH +R RSRS R R + +HR+ HG + R +E R R ++++
Sbjct: 253 RHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKERE 312
Query: 645 RSRTRDSSWSRRSQTLSLSSESTSRSRSRSSDH-GKRRSRSRNRDRYYLRNNYGSRYKWE 703
+ R R S R + S RSRSRS D G RR R R R++ N G R +
Sbjct: 313 KERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREK---ENERGRRRDRD 369
Query: 704 YTYYSRNKDRDGYESSYRRRTLSRAHYSRQSSSPEFRV--------QSFSERTNARKKNN 755
Y +K+R R R+ R+ R E + + ++ +++K+
Sbjct: 370 Y-----DKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKK 424
Query: 756 HSERKYYYYERHRSRSLSSNR-SRTASTGTDRVRNEKPGGKRKYKTRHLEG----TNEVA 810
HS R +HRSRS S N R+ S ++ K K K R G T+ V
Sbjct: 425 HS-RSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVE 483
Query: 811 QPSREFASKAKDSHYQKSSSKLDGNYKNESDTFSDSRSSDRETKHKRRKRKTRSLSVEIV 870
+ + S +K+ ++S SK + ++ SD S D+ KH RR RS S+E
Sbjct: 484 KSKKREHSPSKEKSRKRSRSKERSHKRDHSD------SKDQSDKHDRR----RSQSIE-- 531
Query: 871 YEGKATDTTKHHKKKKKKHKKK 892
+ ++K+HK K
Sbjct: 532 -----------QESQEKQHKNK 542
Score = 78.2 bits (191), Expect = 4e-14
Identities = 76/320 (23%), Positives = 122/320 (38%), Gaps = 58/320 (18%)
Query: 589 HRHRKRGRS--RSSDSRSQSRSGHDQKNHRKHHGKKRMKSKRSRSRESSR-PRGRRDKKR 645
H R+R RS RS R R + +HR+ HG + R +E R R +++++
Sbjct: 254 HVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREK 313
Query: 646 SRTRDSSWSRRSQTLSLSSESTSRSRSRSSDH-GKRRSRSRNRDRYYLRNNYGSRYKWEY 704
R R S R + S RSRSRS D G RR R R R++ N G R +Y
Sbjct: 314 ERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREK---ENERGRRRDRDY 370
Query: 705 TYYSRNKDRDGYESSYRRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSERKYYYY 764
+K+R R R+ R+ R E + + + + +K +
Sbjct: 371 -----DKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKH 425
Query: 765 ERHRSRSLSSNRSRTASTGTDRVRNEKPGGKRKYKTRHLEGTNEVAQPSREFASKAKDSH 824
R RSR +RSR+ S + GKR SR + + H
Sbjct: 426 SRSRSRE-RKHRSRSRS---------RNAGKR----------------SRSRSKEKSSKH 459
Query: 825 YQKSSSKLDGNYKNESDTFSDSRSSDRETKHKRRKRKTRSLSVEIVYEGKATDTTKHHKK 884
+S K + ++ S +DS ++ +H K K+R K
Sbjct: 460 KNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSR--------------------K 499
Query: 885 KKKKHKKKHKKHHGDNASRS 904
+ + ++ HK+ H D+ +S
Sbjct: 500 RSRSKERSHKRDHSDSKDQS 519
Score = 75.5 bits (184), Expect = 2e-13
Identities = 88/334 (26%), Positives = 142/334 (42%), Gaps = 32/334 (9%)
Query: 541 KDEQINKGHCDSSTRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSS 600
+ +I K + + I E +RS S PR S R R + H + G SS
Sbjct: 236 RPRKIKKDGKEGAEEIDRHVERRRSRS---PRRSLSPRRSPR--RSRSRSHHREGHGSSS 290
Query: 601 DSRSQSRSGHDQKNHR--KHHGKKRMKSKRSRSRESSRPRGR-RDKK--RSRTRDSSWSR 655
R R Q+ R K K+R +S RS R R R R R++ RSR+RD R
Sbjct: 291 FDRELEREKERQRLEREAKEREKERRRS-RSIDRGLERRRSRSRERHRSRSRSRDRKGDR 349
Query: 656 RSQTLSLSSESTSRSRSRSSDHGKRRSRSRNRDRYYLR-NNYGSRYKWEYTYYSRNKDRD 714
R + E+ R R R D+ K R R ++R R + R + E +D+D
Sbjct: 350 RDRDREREKEN-ERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKD 408
Query: 715 GYESSYRRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSERKYYYYERHRSRSLSS 774
+R + +S S E + +S S NA K++ ++ ++ S+ S+
Sbjct: 409 DRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSN 468
Query: 775 NRSRTASTG-TDRVRNEKPGGKRKYKTRHLEGTNEVAQPSREFASKAKDSHYQKSSSKLD 833
RSR+ S G TD V K KR++ PS+E S+ + ++S +
Sbjct: 469 KRSRSGSQGRTDSVEKSK---KREH------------SPSKE-KSRKRSRSKERSHKRDH 512
Query: 834 GNYKNESDTFSDSRSS--DRETKHKRRKRKTRSL 865
+ K++SD RS ++E++ K+ K K ++
Sbjct: 513 SDSKDQSDKHDRRRSQSIEQESQEKQHKNKDETV 546
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 83.2 bits (204), Expect = 1e-15
Identities = 116/460 (25%), Positives = 185/460 (40%), Gaps = 46/460 (10%)
Query: 448 ELVTGGATSQIQ---GVQTNDDLNNDSDDSSDNCVIVG-FVKPLAERTPELVELSSDSED 503
EL +T++ Q G+ + + +N S SS G + P E++ E+SS +
Sbjct: 209 ELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVK- 267
Query: 504 LGSYEKMET-VKTQEQEQSYSSGDSDVSRCSSPHSVLGKDEQINKGHCDSSTRIKS---- 558
SY + T + Q QS S S HS + + + H + +R +
Sbjct: 268 --SYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRV-RSHSWKRNHSRARSRTRKGILS 324
Query: 559 ---KKEEKRSTSLSSPRNLNSSVRGDRVYS----PYNHRHRKRGRSRSSD------SRSQ 605
+ + RS S +N + + R R ++ P R RS S + S +
Sbjct: 325 QMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPR 384
Query: 606 SRSGHDQK---NHRKHHGKKRMKSK-RSRSRESSRPRGRRDKKRSRT----RDSSWSR-- 655
SG Q N ++ H + R +K R RSR S P RD+ RSR+ RD S SR
Sbjct: 385 KESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRS-PYKARDRSRSRSPNKARDCSRSRSP 443
Query: 656 ---RSQTLSLS-SESTSRSRSRSSDHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNK 711
R ++ S S +++ SRSRS + + RSRSR+ + + GS K SR+
Sbjct: 444 YKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSP 503
Query: 712 DRDGYESSYRRRTLSRAH-YSRQSSSPEFRVQSFSERTNARKKNNHSERKYYYYERHRSR 770
++ R + R H SR S R QS S + + S + + + RS
Sbjct: 504 SKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSP 563
Query: 771 SLSSNRSRTASTGTDRVRNEKPGGKRKYKTRHLEGTNEVAQPSREFASKAKDSHYQKSSS 830
S +R R S +R R + + N+ + SR AS + +H + +
Sbjct: 564 SKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTP 623
Query: 831 KLDGNYKNESDTFSDSRSSD----RETKHKRRKRKTRSLS 866
+GN+ + +S S R KR +T SLS
Sbjct: 624 SKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLS 663
Score = 62.8 bits (151), Expect = 2e-09
Identities = 69/275 (25%), Positives = 110/275 (40%), Gaps = 51/275 (18%)
Query: 514 KTQEQEQSYSSGDS-DVSRCSSPHSVLGKDEQINKGHCDSSTRIKS-KKEEKRSTSLSSP 571
K +++ +S S + D SR SP+ + + +R +S K RS S S
Sbjct: 421 KARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPS 480
Query: 572 RNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRS-QSRSGHDQKNHRKHHGKKRMKSKR-- 628
+ + S G SP R +R RS S + + QSRS +++HR+ + + +R
Sbjct: 481 KERDHSQLG----SPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQS 536
Query: 629 -----------SRS-------RESSRPRGRRDKKRSRTRDSSWSRRSQTLSLSSESTSRS 670
SRS R+S P RD++R R+ RR S SRS
Sbjct: 537 RSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRS 596
Query: 671 RSRSSDHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRDGYESSYRRRTLSRAHY 730
RS + G R R+ ++++ + R SR ++G S + RT S+
Sbjct: 597 RSPNKQSGYSRPRASSKEKAHSR--------------SRTPSKEGNHS--QSRTSSKESD 640
Query: 731 SRQSSSPE--------FRVQSFSERTNARKKNNHS 757
QS+ P R S S+ K ++HS
Sbjct: 641 PSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHS 675
Score = 46.2 bits (108), Expect = 2e-04
Identities = 80/355 (22%), Positives = 136/355 (38%), Gaps = 42/355 (11%)
Query: 622 KRMKSKRSRSRESSRPRGR---RDKKRSRTRDSSWSRRSQTLSLSSESTSRSRSRSSDHG 678
K KS ++ S+RP R R K R+ +R S+ +R S+ S S R R H
Sbjct: 63 KSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKA---SKASDVRCHQRRGTHS 119
Query: 679 KRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRDGYESSYRRRTLSRAHYSRQSSSPE 738
+ R+ R R R+ + + R G S R T S+ SR S
Sbjct: 120 RGRTPGRRGSRSSKRSPSRASTPGRIRTHGA---RPGMASRVRTPT-SQQKGSRGKSYGR 175
Query: 739 FRVQSFSERTNARKKNNHSERKYYYYERHRSRSLSSNRSRTASTGT----------DRVR 788
R + ER++++ +N +K Y SS + T ST ++
Sbjct: 176 PRTSN-RERSDSQPRN--LSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSD 232
Query: 789 NEKPGGKRKYKT--RHLEGTNEVAQPSREFASKAKDSHYQKSSSKLDGNYKNESD----- 841
N P RK K+ + + + E + E +S+ K + + S+ + ++ S
Sbjct: 233 NPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRS 292
Query: 842 -----TFSDSRSSDRETKHKRRKRKTRSLSVEIVYEGKATDTTKHHKKKKKKHKKKHKKH 896
T S RS + H R + +TR + + G+ + + H K K + + ++
Sbjct: 293 GSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQM--GRHSQSRSHSKGKSQNQSRTPRRG 350
Query: 897 HGDNASRSPVVITIDSDSDKDSEVKEDTECDNSGPQDPLQNEFLAPSLEPFETKD 951
N SR+P S S S+ E D+ G P + + S P + +D
Sbjct: 351 RSHNWSRNPSKERSHSHSRSSSK-----ERDHRGSSSPRKESGRSQSGSPNKQRD 400
Score = 44.3 bits (103), Expect = 6e-04
Identities = 47/200 (23%), Positives = 76/200 (38%), Gaps = 11/200 (5%)
Query: 499 SDSEDLGSYEKMETVKTQEQEQSYSSG---DSDVSRCSSPHSVLGKDEQINKGHCDSSTR 555
S S++ K +++ QS S D SR S + +K R
Sbjct: 514 SSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWR 573
Query: 556 IKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRSQSRSGHDQKNH 615
SK+ E+R + SS +S R S Y+ S SR+ S+ G+ ++
Sbjct: 574 SPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSR 633
Query: 616 RKHHGKKRMKS--------KRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTLSLSSEST 667
+S KRS +R SS + R K S S++ QTLS
Sbjct: 634 TSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQA 693
Query: 668 SRSRSRSSDHGKRRSRSRNR 687
+ S+++ G+R S S ++
Sbjct: 694 DATTSKATLPGERSSSSSSK 713
>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
Length = 2426
Score = 81.3 bits (199), Expect = 4e-15
Identities = 94/318 (29%), Positives = 124/318 (38%), Gaps = 27/318 (8%)
Query: 471 SDDSSDNCVIVGFVKPLAERTPELVELSSDSEDLGSYEKMETVK-TQEQEQSYSSGDSDV 529
SD D V + ER E S SE+ YE VK T E+ + + D
Sbjct: 1759 SDVGRDRSAASPVVSSMPERASE-----SSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGE 1813
Query: 530 SRCSSPHSVLGKDEQINKGHCDSSTRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNH 589
S+ + ++ S+ KS+K S S + R+ S + S
Sbjct: 1814 KEKKRDSSLRSRSKR------SKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRS---- 1863
Query: 590 RHRKRGRSRSSDSRSQSRSGHDQKNHRKHHGKKRMKSKRSRSRESSRPRGRRDKKRSRTR 649
R R R R RSS SRS+SR ++ K R R R+ S R R R+R+R
Sbjct: 1864 RSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSR 1923
Query: 650 DSSWSRRSQTLSLSSESTSRSRSRS-SDHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYS 708
S RS T S S S R RS S RRSR+ +R R+ SR + S
Sbjct: 1924 TPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSR-----RSRTPSRRSRTPSRRS 1978
Query: 709 RNKDRDGYESSYRRRTLSRAHYSRQSSSPEFRVQSFS-ERTNARKKNNHSERKYYYYERH 767
R R S R RT SR R+ S R +SFS R+ R++
Sbjct: 1979 RTPSRRSRTPSRRSRTPSR----RRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIR 2034
Query: 768 RSRSLSSNRSRTASTGTD 785
R RS SS R R+ TD
Sbjct: 2035 RKRSRSSERGRSPKRLTD 2052
Score = 41.6 bits (96), Expect = 0.004
Identities = 57/270 (21%), Positives = 99/270 (36%), Gaps = 21/270 (7%)
Query: 641 RDKKRSRTRDSSWSRRSQTLSLSSESTSRSRSRSSDHGKRRSRSRNRDRYYLRNNYGSRY 700
RD+ + SS R+ S + + D ++ +++NRD+ S
Sbjct: 1763 RDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSL 1822
Query: 701 KWEYTYYSRNKDRDGYESSYRRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSERK 760
+ SR+K E R+RT +R+ SS +S S R+ R ++ R
Sbjct: 1823 R------SRSKRSKSSEHKSRKRTSESRSRARKRSS-----KSKSHRSQTRSRSRSRRR- 1870
Query: 761 YYYYERHRSRSLSSNRSRTASTGTDRVRNEKPGGK---RKYKTRHLEGTNEVAQPSREFA 817
R SRS S +R R + + R R+ K K RK K + +
Sbjct: 1871 -----RRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTP 1925
Query: 818 SKAKDSHYQKSSSKLDGNYKNESDTFSDSRSSDRETKHKRR-KRKTRSLSVEIVYEGKAT 876
S+ SH + + S + S SR S ++ R R++R+ S + +
Sbjct: 1926 SRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRS 1985
Query: 877 DTTKHHKKKKKKHKKKHKKHHGDNASRSPV 906
T + + ++ + S SPV
Sbjct: 1986 RTPSRRSRTPSRRRRSRSVVRRRSFSISPV 2015
Score = 38.5 bits (88), Expect = 0.033
Identities = 47/188 (25%), Positives = 77/188 (40%), Gaps = 20/188 (10%)
Query: 856 KRRKRKTRSLSVEI-----VYEGKATDTTKHHKKKKKKHK---KKHKKHHGDNASRSPVV 907
K RK+R +SV+ + K+ KH KKKKK K KK+K+ ++ S++
Sbjct: 84 KEGSRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQPEESESKTKSH 143
Query: 908 ITIDSDSDKDSEVKEDTECDNSGPQDPLQNEFLAPSLEPFETKDVVTIEAEFGVLDKECD 967
+ D + DS +K D+E + E + P ET + + E V+ E
Sbjct: 144 DDGNIDLESDSFLKFDSE------PSAVALELPTRAFGPSETNESPAVVLEPPVVSMEVS 197
Query: 968 IATLSNNLNNANKTVDNIPPLAASVEQTLDVREESTFVSDLENQPSNIVSLQTEPSRQLP 1027
+ L A KT + SV T + E+S + +PS L + + +P
Sbjct: 198 EPHILETLKPATKTAE------LSVVSTSVISEQSEQSVAVMPEPSMTKILDSFAAAPVP 251
Query: 1028 SPRTSLMS 1035
+ L S
Sbjct: 252 TTTLVLKS 259
>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
Length = 2303
Score = 81.3 bits (199), Expect = 4e-15
Identities = 94/318 (29%), Positives = 124/318 (38%), Gaps = 27/318 (8%)
Query: 471 SDDSSDNCVIVGFVKPLAERTPELVELSSDSEDLGSYEKMETVK-TQEQEQSYSSGDSDV 529
SD D V + ER E S SE+ YE VK T E+ + + D
Sbjct: 1759 SDVGRDRSAASPVVSSMPERASE-----SSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGE 1813
Query: 530 SRCSSPHSVLGKDEQINKGHCDSSTRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNH 589
S+ + ++ S+ KS+K S S + R+ S + S
Sbjct: 1814 KEKKRDSSLRSRSKR------SKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRS---- 1863
Query: 590 RHRKRGRSRSSDSRSQSRSGHDQKNHRKHHGKKRMKSKRSRSRESSRPRGRRDKKRSRTR 649
R R R R RSS SRS+SR ++ K R R R+ S R R R+R+R
Sbjct: 1864 RSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSR 1923
Query: 650 DSSWSRRSQTLSLSSESTSRSRSRS-SDHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYS 708
S RS T S S S R RS S RRSR+ +R R+ SR + S
Sbjct: 1924 TPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSR-----RSRTPSRRSRTPSRRS 1978
Query: 709 RNKDRDGYESSYRRRTLSRAHYSRQSSSPEFRVQSFS-ERTNARKKNNHSERKYYYYERH 767
R R S R RT SR R+ S R +SFS R+ R++
Sbjct: 1979 RTPSRRSRTPSRRSRTPSR----RRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIR 2034
Query: 768 RSRSLSSNRSRTASTGTD 785
R RS SS R R+ TD
Sbjct: 2035 RKRSRSSERGRSPKRLTD 2052
Score = 41.6 bits (96), Expect = 0.004
Identities = 57/270 (21%), Positives = 99/270 (36%), Gaps = 21/270 (7%)
Query: 641 RDKKRSRTRDSSWSRRSQTLSLSSESTSRSRSRSSDHGKRRSRSRNRDRYYLRNNYGSRY 700
RD+ + SS R+ S + + D ++ +++NRD+ S
Sbjct: 1763 RDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSL 1822
Query: 701 KWEYTYYSRNKDRDGYESSYRRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSERK 760
+ SR+K E R+RT +R+ SS +S S R+ R ++ R
Sbjct: 1823 R------SRSKRSKSSEHKSRKRTSESRSRARKRSS-----KSKSHRSQTRSRSRSRRR- 1870
Query: 761 YYYYERHRSRSLSSNRSRTASTGTDRVRNEKPGGK---RKYKTRHLEGTNEVAQPSREFA 817
R SRS S +R R + + R R+ K K RK K + +
Sbjct: 1871 -----RRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTP 1925
Query: 818 SKAKDSHYQKSSSKLDGNYKNESDTFSDSRSSDRETKHKRR-KRKTRSLSVEIVYEGKAT 876
S+ SH + + S + S SR S ++ R R++R+ S + +
Sbjct: 1926 SRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRS 1985
Query: 877 DTTKHHKKKKKKHKKKHKKHHGDNASRSPV 906
T + + ++ + S SPV
Sbjct: 1986 RTPSRRSRTPSRRRRSRSVVRRRSFSISPV 2015
Score = 38.5 bits (88), Expect = 0.033
Identities = 47/188 (25%), Positives = 77/188 (40%), Gaps = 20/188 (10%)
Query: 856 KRRKRKTRSLSVEI-----VYEGKATDTTKHHKKKKKKHK---KKHKKHHGDNASRSPVV 907
K RK+R +SV+ + K+ KH KKKKK K KK+K+ ++ S++
Sbjct: 84 KEGSRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQPEESESKTKSH 143
Query: 908 ITIDSDSDKDSEVKEDTECDNSGPQDPLQNEFLAPSLEPFETKDVVTIEAEFGVLDKECD 967
+ D + DS +K D+E + E + P ET + + E V+ E
Sbjct: 144 DDGNIDLESDSFLKFDSE------PSAVALELPTRAFGPSETNESPAVVLEPPVVSMEVS 197
Query: 968 IATLSNNLNNANKTVDNIPPLAASVEQTLDVREESTFVSDLENQPSNIVSLQTEPSRQLP 1027
+ L A KT + SV T + E+S + +PS L + + +P
Sbjct: 198 EPHILETLKPATKTAE------LSVVSTSVISEQSEQSVAVMPEPSMTKILDSFAAAPVP 251
Query: 1028 SPRTSLMS 1035
+ L S
Sbjct: 252 TTTLVLKS 259
>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
Length = 330
Score = 78.2 bits (191), Expect = 4e-14
Identities = 70/204 (34%), Positives = 98/204 (48%), Gaps = 29/204 (14%)
Query: 504 LGSYEKMETVKTQEQEQSYSSGDSDVSRCSSPHSVLGKDEQINKGHCDSSTRIKSKKEEK 563
+G ++ V+ +E E D D+S+ D ++K + D+S S K++
Sbjct: 139 VGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKS 198
Query: 564 RSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRSQSRSGHDQKNHRKHHGKKR 623
S S R+ +S R SP + R R R RSRSS S SQSRS
Sbjct: 199 NRRSRSKSRSSHSR-SSSRSSSPSSSRSRSRSRSRSSSS-SQSRS--------------- 241
Query: 624 MKSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTLSLSSES----TSRSRSRSSDHG- 678
RS SRE SR RG + + SR+ S S R ++ S SS S RSRSRSS G
Sbjct: 242 ----RSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGD 297
Query: 679 --KRRSRSRNRDRYYLRNNYGSRY 700
KRR+RSR+ +R + R++ GS +
Sbjct: 298 RKKRRTRSRSPERRH-RSSSGSSH 320
Score = 60.8 bits (146), Expect = 6e-09
Identities = 81/293 (27%), Positives = 114/293 (38%), Gaps = 56/293 (19%)
Query: 491 TPELVELSSDSEDLGSYEKMETVKTQEQEQSYSSGDSDVSRCSSPHSVLGKDEQINKGHC 550
TP+ +L + G + + E V+ E+E+S D G+ ++ +G
Sbjct: 90 TPKYAKLEERTGYGGGFNERENVEYIEREESDGEYDE-----------FGRKKKKYRGKA 138
Query: 551 DSSTRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRSQSRSGH 610
I + E+K S D S Y K D S+
Sbjct: 139 VGPASILKEVEDKESEGEEEDE--------DEDLSKY-----KLDEDEDEDDADLSKYNL 185
Query: 611 DQKNHRKHHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTLSLSSESTSRS 670
D + KK + RS+SR S RS +R SS S SS S SRS
Sbjct: 186 DASEEEDSNKKKSNRRSRSKSRSSH--------SRSSSRSSSPS--------SSRSRSRS 229
Query: 671 RSRSSDHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRDGYESSYRRRTLSRAHY 730
RSRSS + RSRS +R+R R GS+ SR+ R SS R + Y
Sbjct: 230 RSRSSSSSQSRSRSSSRERSRSR---GSK--------SRSSSRSHRGSSSPR----KRSY 274
Query: 731 SRQSSSPE-FRVQSFSERTNARKKNNHSERKYYYYERHRSRSLSSNRSRTAST 782
S SSSPE R +S S +++ + R RHRS S SS+ +S+
Sbjct: 275 SSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSS 327
Score = 48.5 bits (114), Expect = 3e-05
Identities = 53/185 (28%), Positives = 78/185 (42%), Gaps = 42/185 (22%)
Query: 708 SRNKDRDGYESSYRRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSERKYYYYERH 767
S +D + +S+ R R+ SR+ +SR SS R + S R R
Sbjct: 188 SEEEDSNKKKSNRRSRSKSRSSHSRSSS---------------RSSSPSSSRS-----RS 227
Query: 768 RSRSLSSNRSRTASTGTDRVRNEKPGGKRKYKTRHLEGTNEVAQPSREFASKAKDSHYQK 827
RSRS SS+ S++ S + R R+ G K + +R G +S + Y
Sbjct: 228 RSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRG-----------SSSPRKRSYSS 276
Query: 828 SSSKLDGNYKNESDTFSDSRSSDRETKHKRRKRKTRSLSVEIVYEGKATDTTKHHKKKKK 887
SSS + N K S SRSS + R+KR+TRS S E + + + H +
Sbjct: 277 SSSSPERNRKR-----SRSRSS---SSGDRKKRRTRSRSPERRHRSSSGSS---HSGSRS 325
Query: 888 KHKKK 892
KKK
Sbjct: 326 SSKKK 330
Score = 48.1 bits (113), Expect = 4e-05
Identities = 52/205 (25%), Positives = 83/205 (40%), Gaps = 24/205 (11%)
Query: 453 GATSQIQGVQTNDDLNNDSDDSSDNCVIVGFVKPLAERTPELVELSSDSEDLGSYEKMET 512
G S ++ V+ + + D+ D + K + + +LS + D E
Sbjct: 140 GPASILKEVEDKESEGEEEDEDED----LSKYKLDEDEDEDDADLSKYNLDASEEEDSNK 195
Query: 513 VKT--QEQEQSYSSGDSDVSRCSSPHSVLGKDEQINKGHCDSSTRIKSKKEEKRSTSLSS 570
K+ + + +S SS SR SSP S + ++ S +R +S E+ + S
Sbjct: 196 KKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSK 255
Query: 571 PRNLNSSVRGD-----RVYSPYN---HRHRKRGRSRSSDSRSQSRSGHDQKNHRKHHGKK 622
R+ + S RG R YS + R+RKR RSRSS S D+K R +
Sbjct: 256 SRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSS-------SSGDRKKRRT---RS 305
Query: 623 RMKSKRSRSRESSRPRGRRDKKRSR 647
R +R RS S G R + +
Sbjct: 306 RSPERRHRSSSGSSHSGSRSSSKKK 330
Score = 43.9 bits (102), Expect = 8e-04
Identities = 57/216 (26%), Positives = 85/216 (39%), Gaps = 24/216 (11%)
Query: 603 RSQSRSGHDQ--KNHRKHHGK--------KRMKSKRSRSRESSRPRGRRDKKRSRTRDSS 652
R +S +D+ + +K+ GK K ++ K S E K D
Sbjct: 117 REESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDED 176
Query: 653 WSRRSQ-TLSLSSESTS-------RSRSRS-SDHGKRRSRSRNRDRYYLRNNYGSRYKWE 703
+ S+ L S E S RSRS+S S H + SRS + R+ SR
Sbjct: 177 DADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSS 236
Query: 704 YTYYSRNKDRDGYES-SYRRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSERKYY 762
SR+ R+ S + R+ SR+H R SSSP R S S + R + R
Sbjct: 237 SQSRSRSSSRERSRSRGSKSRSSSRSH--RGSSSPRKRSYSSSSSSPERNRKRSRSRSSS 294
Query: 763 YYER--HRSRSLSSNRSRTASTGTDRVRNEKPGGKR 796
+R R+RS S R +S+G+ + K+
Sbjct: 295 SGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSKKK 330
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 78.2 bits (191), Expect = 4e-14
Identities = 107/458 (23%), Positives = 179/458 (39%), Gaps = 93/458 (20%)
Query: 490 RTPELVELSSDSEDLGSYEKMETVKTQEQEQSYSSGDSDVSRCSSPHSVLGKDEQIN--K 547
R P S S + + ET QE + + S + G ++N K
Sbjct: 336 RGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQR---MRVSSGERWIKGDKSELNEIK 392
Query: 548 GHCDSSTRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRSQSR 607
+ S R+K +K ++ RN++ S N + +K +S+ R
Sbjct: 393 ENQRSPVRVKERK-------ITDHRNVSESPNRK------NEKEKKVKDHKSNSKERDIR 439
Query: 608 SGHDQKNHRKHHGKKRMKSK-RSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTLSLSSES 666
++ + K+ KKR KSK RS+S+E K +S+ RDS +R + E
Sbjct: 440 RNSEKDDKYKNKVKKRAKSKSRSKSKE---------KSKSKERDSKHNR-------NEEK 483
Query: 667 TSRSRSRSSDHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRDGYESSYRRRTL- 725
RSRS+ DH + + + D S+ KD++ S + + L
Sbjct: 484 RMRSRSKGRDHENVKEKEKQSD-------------------SKGKDQERSRSKEKSKQLE 524
Query: 726 --SRAHYSRQSSSPEFRVQSFSERTNARKKNNHSERKYYYYERHRSRSLSSNRSRTASTG 783
S H +S + R QS S + K K+ Y R R RS S +RSR +
Sbjct: 525 SKSNEHDHSKSKEKDRRAQSRSRECDITK------GKHSYNSRTRERSRSRDRSRRVRSR 578
Query: 784 T---DRVRNEKPGGKRKYKTRHLEGTNEVAQPSREFASKAKDSHYQKSSSKLDGNYKNES 840
T DR R+++ R+ + R + + + S++KD ++
Sbjct: 579 THDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRR------------- 625
Query: 841 DTFSDSRSSDRETKHKRRKRKTRSLSVEIVYEGKATDTTKHHKKKKKKHKKKHKKHHGDN 900
DSRSS+RE R K K R+ E K++ H K+ + K+ + K N
Sbjct: 626 ---RDSRSSEREESQSRNKDKYRN------QESKSS----HRKENSESEKRMYSKSRDHN 672
Query: 901 ASRSPVVITIDSDSDKDSEVKEDTECDNSGPQDPLQNE 938
+S + D D S++K+ ++ DN L+N+
Sbjct: 673 SSNNSREKKADRDQSPFSKIKQSSQ-DNELKSSMLKNK 709
Score = 77.4 bits (189), Expect = 6e-14
Identities = 88/335 (26%), Positives = 144/335 (42%), Gaps = 39/335 (11%)
Query: 536 HSVLGKDEQINKGHCDSSTRIKSK-KEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKR 594
H K+ I + + + + K+K K+ +S S S + + S D S +N KR
Sbjct: 429 HKSNSKERDIRR-NSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERD---SKHNRNEEKR 484
Query: 595 GRSRSS--------DSRSQSRS-GHDQKNHRKHHGKKRMKSKRSRSRES-SRPRGRRDKK 644
RSRS + QS S G DQ+ R K+++SK + S S+ + RR +
Sbjct: 485 MRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQS 544
Query: 645 RSRTRDSSWSRRSQTLSLSSESTSRSRSRSSDHGKRRSRSRNRDRYYLRNNYGSRYK-WE 703
RSR D + + S S +R RSRS D RR RSR DR R+ RY+ E
Sbjct: 545 RSRECDITKGKHSY------NSRTRERSRSRDR-SRRVRSRTHDRDRSRSKEYHRYREQE 597
Query: 704 YTYYSRNKDRDGYESSYRRRTLSRAHYSRQSSSPE---------FRVQSFSERTNARKKN 754
Y R++ R+ R R+ R R S S E + ++ +++ RK+N
Sbjct: 598 YRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKEN 657
Query: 755 NHSERKYYYYERHRSRSLSSNRSRTASTGTDRVRNEKPGGKRKYKTRHLEGTNEVAQPSR 814
+ SE++ Y R + SSN SR R++ P K K ++ E + + +
Sbjct: 658 SESEKRMYSKSRDHN---SSNNSREKKAD----RDQSPFSKIKQSSQDNELKSSMLKNKE 710
Query: 815 EFASKAKDSHYQKSSSKLDGNYKNESDTFSDSRSS 849
+ ++ + S + ++ +E + D SS
Sbjct: 711 DEKIRSSVEKENQKSKGQENDHVHEKNKKFDHESS 745
Score = 71.6 bits (174), Expect = 4e-12
Identities = 74/281 (26%), Positives = 118/281 (41%), Gaps = 36/281 (12%)
Query: 511 ETVKTQEQEQSYSSGDSDVSRCSSPHSVLGKDEQINKGHCDSSTRIKSKKEEKRSTSLSS 570
E VK +E++ D + SR L E + H S ++ K ++ + RS
Sbjct: 495 ENVKEKEKQSDSKGKDQERSRSKEKSKQL---ESKSNEHDHSKSKEKDRRAQSRSRECDI 551
Query: 571 PRNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRSQSRSGHDQ-----KNHRKHHGKKRMK 625
+ +S YN R R+R RSR R +SR+ HD+ K + ++ ++ +
Sbjct: 552 TKGKHS----------YNSRTRERSRSRDRSRRVRSRT-HDRDRSRSKEYHRYREQEYRR 600
Query: 626 SKRSRSRESSRPRGRRDKK--RSRTRDSSWSRRSQTLSLSSESTSRSRSRSSDHGKRRSR 683
RSRSRE P GR K R R RDS S R ++ S + + S+SS H K S
Sbjct: 601 RGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSS-HRKENSE 659
Query: 684 SRNRDRYYLRNNYGSRYKWEYTYYSRNKDRDGYESSYRRRTLSRAHYSRQSS----SPEF 739
S R R++ S SR K D +S + + S +SS +
Sbjct: 660 SEKRMYSKSRDHNSSN-------NSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDE 712
Query: 740 RVQSFSERTNARKK---NNHSERKYYYYERHRSRSLSSNRS 777
+++S E+ N + K N+H K ++ S ++S
Sbjct: 713 KIRSSVEKENQKSKGQENDHVHEKNKKFDHESSPGTDEDKS 753
Score = 69.7 bits (169), Expect = 1e-11
Identities = 86/427 (20%), Positives = 174/427 (40%), Gaps = 62/427 (14%)
Query: 516 QEQEQSYSSGDSDVSRCSSPHSVLGKDEQINKGHCDSSTRIKSKKEEKRSTSLSSPRNLN 575
+E+++ + S S S S S + +S+T KSKK +K+
Sbjct: 185 KEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHR--------- 235
Query: 576 SSVRGDRVYSPYNHRHRKRGRSRSSDSRSQSRSGHDQKNHRKHH----GKKRMKSKRSRS 631
+ R + + +K +S SS+S +++ Q R + R ++S
Sbjct: 236 ---KNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPP 292
Query: 632 RESSRPRGRRDKKRSR------TRDSSWSRRSQTLSLSSESTSRSRSRSSDHGKRRSRSR 685
+ + R R+++R R ++ +S+ RR L + S + + R + SRSR
Sbjct: 293 KADEKERKNRERERERECNPPNSQPASYQRRL----LVTRSGRKIKGRGPRRYRTPSRSR 348
Query: 686 NRDRYYLRNNYGSRYKWEYTYYSR-----------------NKDRDGYESSYRRRTLSRA 728
+RDR + R+ ++ E R N+ ++ S R +
Sbjct: 349 SRDR-FRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKIT 407
Query: 729 HYSRQSSSP------EFRVQSFSERTNAR--KKNNHSERKYYYYERHRSRSLSSNRSRTA 780
+ S SP E +V+ + R ++N+ + KY + R++S S ++S+
Sbjct: 408 DHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEK 467
Query: 781 STGTDRVRNEKPGGKRKYKTRHLEGTNE-VAQPSREFASKAKDSHYQKSSSKLDGNYKNE 839
S +R +++ ++R +E V + ++ SK KD +S K +++
Sbjct: 468 SKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEK-SKQLESK 526
Query: 840 SDTFSDSRSSDRETKHKRRKRKTRSLSVEIVYEGKAT--DTTKHHKKKKKKHKKKHKKHH 897
S+ S+S K K R+ ++RS +I +GK + T+ + + + ++ + H
Sbjct: 527 SNEHDHSKS-----KEKDRRAQSRSRECDIT-KGKHSYNSRTRERSRSRDRSRRVRSRTH 580
Query: 898 GDNASRS 904
+ SRS
Sbjct: 581 DRDRSRS 587
Score = 68.9 bits (167), Expect = 2e-11
Identities = 89/379 (23%), Positives = 153/379 (40%), Gaps = 45/379 (11%)
Query: 557 KSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRSQSRSGHDQKNHR 616
K KKEEK+ SS + +SS S + + S S+S ++ +S +K HR
Sbjct: 182 KVKKEEKKRHKSSSSSSSSSSD------SDSSSDSQSSSDSSDSESATEEKSKKRKKKHR 235
Query: 617 KH---HGKKRMKSKRSRSRESSRPRGRRDKKRSRT-----------RDSSWSRRSQTLSL 662
K+ H K++ K K+S+ SS + + ++ + R+S +
Sbjct: 236 KNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKAD 295
Query: 663 SSESTSRSRSRSSDHGKRRSRSRNRDRYYLRNNYGSRYKW----EYTYYSRNKDRDGYES 718
E +R R R + S+ + R L G + K Y SR++ RD +
Sbjct: 296 EKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRR 355
Query: 719 S----YRRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHS-----ERKYYYYERHRS 769
S + R+ + RA R SS + ++ N K+N S ERK HR+
Sbjct: 356 SETPPHWRQEMQRAQRMRVSSGERW-IKGDKSELNEIKENQRSPVRVKERK---ITDHRN 411
Query: 770 RSLSSNRSRTASTGTDRVRNEKPGGKRKYKTRHLEGTNEVAQPSREFA-SKAKDSHYQKS 828
S S NR +V++ K K + R+ E ++ ++ A SK++ +KS
Sbjct: 412 VSESPNRKNEKE---KKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKS 468
Query: 829 SSK-LDGNYKNESDTFSDSRSSDRETKHKRRKRKTRSLSVEIVYEGKATDTTKHHKKKKK 887
SK D + + SRS R+ ++ + K K + ++ + +K + K
Sbjct: 469 KSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSN 528
Query: 888 KH---KKKHKKHHGDNASR 903
+H K K K + SR
Sbjct: 529 EHDHSKSKEKDRRAQSRSR 547
Score = 43.9 bits (102), Expect = 8e-04
Identities = 69/298 (23%), Positives = 114/298 (38%), Gaps = 34/298 (11%)
Query: 637 PRGRRDKKRSRTRDSSWSRRSQTLSLSSESTSRSRSRSSD-HGKRRSRSRNRDRYYLRNN 695
P+ + K+ + SS S S + S S S+S S SSD +S+ R + + +N+
Sbjct: 179 PKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNS 238
Query: 696 YGSRYKWEYTYYSRNKDRDGYESSYRRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNN 755
++K E ++K ES R P F R + K +
Sbjct: 239 --RKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKAD- 295
Query: 756 HSERKYYYYERHRSRSLSSNRSRTAS-----TGTDRVRNEKPGGKRKYKTRHLEGTNEVA 810
E++ ER R R + S+ AS T R K G R+Y+T
Sbjct: 296 --EKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRT---------- 343
Query: 811 QPSREFASKAKDSHYQKSSSKLDGNYKNESDTFSDSRSSDRE-----TKHKRRKRKTRSL 865
PSR S+++D + S+ +++ E R S E K + + K
Sbjct: 344 -PSR---SRSRDRFRR---SETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQR 396
Query: 866 SVEIVYEGKATDTTKHHKKKKKKHKKKHK-KHHGDNASRSPVVITIDSDSDKDSEVKE 922
S V E K TD + +K++K+ K K H N+ + + D ++VK+
Sbjct: 397 SPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKK 454
Score = 38.5 bits (88), Expect = 0.033
Identities = 32/137 (23%), Positives = 57/137 (41%), Gaps = 16/137 (11%)
Query: 806 TNEVAQPSREFASKAKDSHYQKSSSKLDGNYKNESDTFSDSRSSDRETKHKRRKRKTRSL 865
T+ ++P E + KS K + +++S + S S SSD ++ + S
Sbjct: 159 TDAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSD 218
Query: 866 SVEIVYEGKATDTTKHHKKKKKKHKKKHKKHHGDNASRSPVVITIDSDSDKDSEVKEDTE 925
S + T + KK+KKKH+K +KH + R S K + + + E
Sbjct: 219 S--------ESATEEKSKKRKKKHRKNSRKHKKEKKKR--------KKSKKSASSESEAE 262
Query: 926 CDNSGPQDPLQNEFLAP 942
+ PQ ++ E + P
Sbjct: 263 NLEAQPQSTVRPEEIPP 279
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 77.0 bits (188), Expect = 8e-14
Identities = 117/447 (26%), Positives = 163/447 (36%), Gaps = 46/447 (10%)
Query: 484 VKPLAERTPELVELSSDSEDLGSYEKMETVKTQEQEQSYSSGDSDVSRCSSPHSVLGKDE 543
V P +E +P + D S EK+ + E S + VSR +S K
Sbjct: 391 VNPPSEASP-----TRDRSPPKSPEKLPQSSSSESSPP-SPQPTKVSRHASSSPESPKPA 444
Query: 544 QINKGHCDSSTRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSR 603
H + S+ SK + S R R SP + R R RSR+ R
Sbjct: 445 PAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAK-RGRSRSRTPTKR 503
Query: 604 SQSRSGHDQ---KNHRKHHGKKRMKSKRSRSRESSRP----------RGR-RDKKRSRTR 649
SRS Q + G+ R +R RSR RP RGR R +R R+
Sbjct: 504 GHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSH 563
Query: 650 DSSWSRRSQTLSLSSESTSRSRSRSSDHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSR 709
S + R ++ S + RSRSR+ + RSR+ R R R T R
Sbjct: 564 SRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSR-----------TPARR 612
Query: 710 NKDRDGYESSYRRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSE---RKYYYYER 766
+ R + R RT S +S SP R RT AR+ + S R+ R
Sbjct: 613 GRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSR 672
Query: 767 HRSRSLSSNRSRT-ASTGTDRVRNEKPGGKRKYKTRHLEGTNEVAQPSREFASKAKDSHY 825
+R +RSRT A G R R + G R ++ G + P R S +
Sbjct: 673 TPARRSGRSRSRTPARRGRSRSRTPRRGRSRS-RSLVRRGRSHSRTPQRRGRSGSSSERK 731
Query: 826 QKSSSKLDGNYKNESDTFSDSRSSDRETK---HKRRKRKTRSLSVEIVYEG-----KATD 877
KS + + N S SR S R ++ R K K+R LS+ G K
Sbjct: 732 NKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSR-LSLRRSLSGSSPCPKQKS 790
Query: 878 TTKHHKKKKKKHKKKHKKHHGDNASRS 904
T + + + K K SRS
Sbjct: 791 QTPPRRSRSGSSQPKAKSRTPPRRSRS 817
Score = 72.8 bits (177), Expect = 2e-12
Identities = 83/265 (31%), Positives = 116/265 (43%), Gaps = 19/265 (7%)
Query: 552 SSTRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRSQSRSGHD 611
SS R K+ RS S PR L S R R R R S S SR + RS
Sbjct: 1749 SSPRTKTTSRRGRSPS-PKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSR 1807
Query: 612 QKNHRKHHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSR-RSQTLSLSSESTSRS 670
+ R+ G S+ +ESSR RR + RSRT +S R RS+T S RS
Sbjct: 1808 SRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRT---SPAPWKRS 1864
Query: 671 RSRSSDHGKRRSRSR----NRDRYYLRNNYGSRYK-WEYTYYSRNKDRDGYESSYRRRTL 725
RSR+S RRSRSR +R R R + SR + T +R + R RRR+
Sbjct: 1865 RSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSR 1924
Query: 726 SR----AHYSRQSSSPEFRVQSFSERTNARKKNNHSERKYYYYERHRSRS--LSSNRSRT 779
SR +S +P R +S S ++ + S R RSR+ ++ RSR+
Sbjct: 1925 SRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRS 1984
Query: 780 ASTGTDRVRNE---KPGGKRKYKTR 801
++ R R+ P +R+ ++R
Sbjct: 1985 RTSPVTRRRSRSRTSPVTRRRSRSR 2009
Score = 71.6 bits (174), Expect = 4e-12
Identities = 80/321 (24%), Positives = 133/321 (41%), Gaps = 31/321 (9%)
Query: 540 GKDEQINKGHCDS-STRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSR 598
G+ +G S S + + + R+ + R R +P R R R +R
Sbjct: 552 GRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPAR 611
Query: 599 SSDSRSQSRSGHDQKNHRKHHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQ 658
SRS++ + ++ R +R RS +R S R R R +R R+R + +RR +
Sbjct: 612 RGRSRSRTPA---RRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGR 668
Query: 659 TLSLS-SESTSRSRSRSSDHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRDGYE 717
+ S + + + RSRSR+ + RSRSR R R+ R ++ + + R G
Sbjct: 669 SRSRTPARRSGRSRSRTPAR-RGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSS 727
Query: 718 SSYRRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSERKYYYYERHRSRSLSSNRS 777
S + ++ + SR +SSPE + S R RSRSLSS RS
Sbjct: 728 SERKNKSRTSQRRSRSNSSPEMKKSRISSR--------------------RSRSLSSPRS 767
Query: 778 RTASTGTDR--VRNEKPGGKRKYKTRHLEGTNEVAQPSREFASKAKDSHYQKSSSKLDGN 835
+ S + R + P K+K +T + +QP + + + S +SSS
Sbjct: 768 KAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRS---RSSSSPPPK 824
Query: 836 YKNESDTFSDSRSSDRETKHK 856
K+++ + SS K K
Sbjct: 825 QKSKTPSRQSHSSSSPHPKVK 845
Score = 71.2 bits (173), Expect = 5e-12
Identities = 82/259 (31%), Positives = 115/259 (44%), Gaps = 35/259 (13%)
Query: 555 RIKSKKEEKRSTSLSSP---RNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRSQSRSGHD 611
+ KS+ +R +S SSP R S R S R R R R S S S
Sbjct: 1679 KTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEK 1738
Query: 612 QKNHRKHHG----KKRMKSKRSRSRESSRPRG-RRDKKRSRTRDSSWSRRSQTLSLSSES 666
++ R+ + + S+R RS S +PRG +R + RSR R+ + + R + S SS+S
Sbjct: 1739 SRSSRRRRSASSPRTKTTSRRGRS-PSPKPRGLQRSRSRSR-REKTRTTRRRDRSGSSQS 1796
Query: 667 TSRSRSRSSDHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRDGYESSYRRRTLS 726
TSR RR RSR+R R R GS Y+SR+ R ESS RT S
Sbjct: 1797 TSR----------RRQRSRSRSRVTRRRRGGS------GYHSRSPARQ--ESS---RTSS 1835
Query: 727 RAHYSRQSSSPEFRVQSFSERTNARKKNNHSERKYYYYERHRSR----SLSSNRSRTAST 782
R R + P R +S S + A K + S + R RSR S +RSRT+
Sbjct: 1836 RRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPV 1895
Query: 783 GTDRVRNEKPGGKRKYKTR 801
R R+ +R+ ++R
Sbjct: 1896 SRRRSRSRTSVTRRRSRSR 1914
Score = 68.9 bits (167), Expect = 2e-11
Identities = 102/394 (25%), Positives = 158/394 (40%), Gaps = 71/394 (18%)
Query: 543 EQINKGHCDSSTRIKS-----KKEEKRSTSLSSP---------RNLNSSVRGDRVYSPYN 588
E +N S TR +S +K + S+S SSP R+ +SS + +P
Sbjct: 389 EPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKP-APAP 447
Query: 589 HRHRKRGRSRSSDSRSQSRSGHDQKNHR---KHHGKKRMKSKRSRSRESSRPRGRRDKKR 645
HR+ S +S +RS R+ D+ + + G+ R + R R SR +R R
Sbjct: 448 GSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSR 507
Query: 646 SRTRDSSWSRRSQTLSLSSESTSRSRSRS--------SDHGKRRSRSRN--RDRYYLRNN 695
SR+ SR +Q S R RSRS S + +RR RSR+ R R + R+
Sbjct: 508 SRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSP 567
Query: 696 YGSRYKWEYTYYSRNKDRDGYESSYRRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNN 755
T R + R + RRR+ SR R+S S RT AR+
Sbjct: 568 ATRGRSRSRTPARRGRSRS--RTPARRRSRSRTPTRRRSRS----------RTPARR--- 612
Query: 756 HSERKYYYYERHRSRSLSSNRSRTASTGTDRVRNEKP---GGKRKYKTRHLEGTNEVAQP 812
R RSR+ + RSRT S R R+ P G+ + +T G + P
Sbjct: 613 ---------GRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTP 663
Query: 813 SREFASKAKDSHYQKSSSKLDGNYKNESDTFSDSRSSDRETKHK-RRKRKTRSLSVEIVY 871
+R S+++ + S+ SR+ R + + R R+ RS S +V
Sbjct: 664 ARRGRSRSRTPARRSGRSR--------------SRTPARRGRSRSRTPRRGRSRSRSLVR 709
Query: 872 EGKATDTTKHHK-KKKKKHKKKHKKHHGDNASRS 904
G++ T + + ++K+K SRS
Sbjct: 710 RGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRS 743
Score = 65.9 bits (159), Expect = 2e-10
Identities = 140/558 (25%), Positives = 202/558 (36%), Gaps = 69/558 (12%)
Query: 375 DCPAPSYEEGSHSDSSVITISPDEAETQELDINVATVSQAPWD--DETPGPSYSSSEQVH 432
D S HS S +SPD E + N ++S D TP SSS
Sbjct: 1370 DMKEQSTRSSGHSSSE---LSPDAVEKAGMSSN-QSISSPVLDAVPRTPSRERSSSASSP 1425
Query: 433 VTMSSLLNTSDSSDEELVTGGATSQIQGVQTNDDLNNDSDDSSDNCVIVGFVKPLAERTP 492
L T + G G + L+ S D + + +P
Sbjct: 1426 EMKDGLPRTPSRRSRSGSSPGLRDG-SGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSP 1484
Query: 493 ELVELSSD----SEDLGSYEKMETVKTQEQEQSYSSGDSDVSRCSSPHSVLGKDEQINKG 548
E L S S E T ++E+S S +S V + + + LG ++ G
Sbjct: 1485 EPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGS--ESSVDQKTVARTPLG--QRSRSG 1540
Query: 549 HCDSSTRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRSQ--- 605
S ++RS S SSP + + +P R R G S DS+S+
Sbjct: 1541 SSQELDVKPSASPQERSESDSSPDSKA------KTRTPLRQRSRS-GSSPEVDSKSRLSP 1593
Query: 606 --SRSGHDQKNHRKHHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSR-RSQTLSL 662
SRSG + K R +S S E P R +RSR+ SS R S S
Sbjct: 1594 RRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSS 1653
Query: 663 SSES---------TSRSRSRSSDHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDR 713
S+ES T+R SRSS K +SR+ R R SR E T +R R
Sbjct: 1654 STESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRR-------SSRSSPELTRKARLSRR 1706
Query: 714 DGYESS---YRRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSERKYYYYERHRSR 770
SS R RT R S SSPE +S S R R R
Sbjct: 1707 SRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSR--------------------RRR 1746
Query: 771 SLSSNRSRTASTGTDRVRNEKPGGKRKYKTR-HLEGTNEVAQPSREFASKAKDSHYQKSS 829
S SS R++T S R + KP G ++ ++R E T + R +S++ Q+S
Sbjct: 1747 SASSPRTKTTSR-RGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSR 1805
Query: 830 SKLDGNYKNESDTFSDSRSSDRETKHKRRKRKTRSLSVEIVYEGKATDTTKHHKKKKKKH 889
S+ + + SRS R+ + R+ R S K + + K+
Sbjct: 1806 SRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSR 1865
Query: 890 KKKHKKHHGDNASRSPVV 907
+ H + SR+P++
Sbjct: 1866 SRASPATHRRSRSRTPLI 1883
Score = 65.9 bits (159), Expect = 2e-10
Identities = 92/332 (27%), Positives = 133/332 (40%), Gaps = 27/332 (8%)
Query: 508 EKMETVKTQEQEQSYSSGDSDVSRCSSPHSVLGKDEQINKGHCDS-----STRIKSKKEE 562
EK T + +++ S S R S V + + H S S+R S++
Sbjct: 1780 EKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRR 1839
Query: 563 KRS----TSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSS-DSRSQSRSGHDQKNHRK 617
RS TS R+ S R S + +R RSR+ SR +SRS + R+
Sbjct: 1840 GRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRR 1899
Query: 618 HHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTLSLSSESTSRSRSRSSDH 677
+ + +RSRSR S P RR RSR+R +RR S S T+R RSRS
Sbjct: 1900 SRSRTSVTRRRSRSRAS--PVSRR---RSRSRTPPVTRRR---SRSRTPTTRRRSRSRTP 1951
Query: 678 GKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRDGYESSYRRRTLSRA-----HYSR 732
R RSR+R R SR + +R + R RRR+ SR SR
Sbjct: 1952 PVTRRRSRSRTPPVTRRRSRSRT----SPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSR 2007
Query: 733 QSSSPEFRVQSFSERTNARKKNNHSERKYYYYERHRSRSLSSNRSRTASTGTDRVRNEKP 792
+SP R +S S A ++ + S +R RSRS + R R+ S R ++
Sbjct: 2008 SRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRS 2067
Query: 793 GGKRKYKTRHLEGTNEVAQPSREFASKAKDSH 824
+ R + + SR A +H
Sbjct: 2068 LTRSPPAIRRRSASGSSSDRSRSATPPATRNH 2099
Score = 58.9 bits (141), Expect = 2e-08
Identities = 86/328 (26%), Positives = 134/328 (40%), Gaps = 34/328 (10%)
Query: 555 RIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRG---RSRSSDSRSQSRSGHD 611
R +S+ +R S R+ + R R SP R R R RS S SR+ +R G
Sbjct: 603 RSRSRTPARRGRS----RSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRS 658
Query: 612 QKNHRKHHGKKRMK-----SKRSRSRESSRPRGR---RDKKRSRTRDSSWSRRSQTLSLS 663
+ G+ R + S RSRSR +R RGR R +R R+R S RR + S
Sbjct: 659 RSRTPARRGRSRSRTPARRSGRSRSRTPAR-RGRSRSRTPRRGRSRSRSLVRRGR----S 713
Query: 664 SESTSRSRSRSSDHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRDGYESSYRRR 723
T + R RS +R+++SR R R+N K R++ S + R
Sbjct: 714 HSRTPQRRGRSGSSSERKNKSRTSQR-RSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSR 772
Query: 724 TLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSERKYYYYERHRSRSLSS----NRSRT 779
R S S P+ + Q+ R+ + ++ + RSRS SS +S+T
Sbjct: 773 LSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSR---TPPRRSRSSSSPPPKQKSKT 829
Query: 780 ASTGTDRVRNEKPGGKRKYKTRHLEGTNEVAQPSREFASKAKDSHYQKSSSKLDGNYKNE 839
S + + P K K T +G+ Q + + + + S ++ S D K+
Sbjct: 830 PSRQSH--SSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSP---DPELKSR 884
Query: 840 SDT-FSDSRSSDRETKHKRRKRKTRSLS 866
+ + S S SS K R++ S S
Sbjct: 885 TPSRHSCSGSSPPRVKSSTPPRQSPSRS 912
Score = 54.3 bits (129), Expect = 6e-07
Identities = 76/260 (29%), Positives = 106/260 (40%), Gaps = 27/260 (10%)
Query: 552 SSTRIKSKKEEKRSTSLSSPRNLNS--SVRGDRVYSPYNHRHRKRGRSRSSD-SRSQSRS 608
S T + S++ + TS S R S SV R S + R+R RSR+ +R +SRS
Sbjct: 1878 SRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRS 1937
Query: 609 GHDQKNHRKHHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTLSLSSESTS 668
R + +RSRSR P R + RSRT S +RR S +
Sbjct: 1938 RTPTTRRRSRSRTPPVTRRRSRSRT---PPVTRRRSRSRT--SPITRRRSRSRTSPVTRR 1992
Query: 669 RSRSRSSDHGKRRSRS------RNRDRYYLRNNYGSRYKWEYTYYSRNKDRDGYESSYRR 722
RSRSR+S +RRSRS R R R R + R + R + RR
Sbjct: 1993 RSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRR 2052
Query: 723 RTLS------RAHYSRQSSSPEFRVQSFSERTNARKKN-------NHSERKYYYYERHRS 769
R+ S R S S P R +S S ++ R ++ NHS + + S
Sbjct: 2053 RSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSS 2112
Query: 770 RSLSSNRSRTASTGTDRVRN 789
R +R + T DR R+
Sbjct: 2113 RMSCFSRPSMSPTPLDRCRS 2132
Score = 52.0 bits (123), Expect = 3e-06
Identities = 31/93 (33%), Positives = 47/93 (50%), Gaps = 7/93 (7%)
Query: 590 RHRKRGRSRSSDSRSQSRSGHDQKNHRKHHGKKRMKSKRSRSRESSRPRGRRDKKRSRTR 649
+ +K+ R R S+S S R +KH + K ++ RS R +DKKR R+R
Sbjct: 190 KKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSR 249
Query: 650 DSSWSRRSQTL-------SLSSESTSRSRSRSS 675
++ + +S+ S SS TSRSRSRS+
Sbjct: 250 STTPAPKSRRAHRSTSADSASSSDTSRSRSRSA 282
Score = 48.1 bits (113), Expect = 4e-05
Identities = 84/385 (21%), Positives = 137/385 (35%), Gaps = 33/385 (8%)
Query: 540 GKDEQINKGHCDSSTRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNH-RHRKRGRSR 598
GK+E + + T ++ EK++ L + ++ S + P R K+
Sbjct: 107 GKEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPE 166
Query: 599 SSDSRSQSRSGHDQKNHRKHHGKKRMKSKRSRSRESSRPRGRRDK--KRSRTRDSSWSRR 656
S R ++ KK+ K R R ESS PR R K K+ + R S S++
Sbjct: 167 PPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKK 226
Query: 657 SQTLSLSSESTSRSRSRSSDHGKRRSRSRN---RDRYYLRNNYGSRYKWEYTYYSRNKDR 713
+ S T +S+ +S D ++RSRS + R R+ T SR++
Sbjct: 227 RKHRS----PTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSA 282
Query: 714 DG--YESSYRRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSERKYYYYE------ 765
+ ++ R+ S A R F + +++ YE
Sbjct: 283 AAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDK 342
Query: 766 RHRSRSLSSNRSRTASTG------TDRVRNEKPGGKRKYKTRHLEGTNEVAQPSREFASK 819
+ +S + S +STG T + G + T L + E P E AS
Sbjct: 343 KEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPL--SQEPVNPPSE-ASP 399
Query: 820 AKDSHYQKSSSKLDGNYKNESDTFSDSRSSDRETKHKRRKRKTRSLSVEIVYEGKATDTT 879
+D KS KL + +ES S S + TK R + G + +
Sbjct: 400 TRDRSPPKSPEKLPQSSSSES-----SPPSPQPTKVSRHASSSPESPKPAPAPGSHREIS 454
Query: 880 KHHKKKKKKH-KKKHKKHHGDNASR 903
K + H + K K H SR
Sbjct: 455 SSPTSKNRSHGRAKRDKSHSHTPSR 479
Score = 39.3 bits (90), Expect = 0.020
Identities = 40/150 (26%), Positives = 58/150 (38%), Gaps = 6/150 (4%)
Query: 535 PHSVLGKDEQINKGHCDSSTRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKR 594
PHS +G+ S+ +E+RS+S SS + +SS S +
Sbjct: 2502 PHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSS------SSSSSSSSSSS 2555
Query: 595 GRSRSSDSRSQSRSGHDQKNHRKHHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWS 654
S SSDS S + ++ + R P + K+RS + SS S
Sbjct: 2556 SGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSS 2615
Query: 655 RRSQTLSLSSESTSRSRSRSSDHGKRRSRS 684
S + S SS S+S S S SS S S
Sbjct: 2616 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2645
Score = 38.5 bits (88), Expect = 0.033
Identities = 73/341 (21%), Positives = 118/341 (34%), Gaps = 29/341 (8%)
Query: 359 ARSPFNMAAFDQHANYDCPAPSYEEGSHSDSSVITISPDEAETQELDINVATVSQAPWDD 418
+R+P + + + + P+PS G S++ + D+ + + + S+
Sbjct: 2407 SRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSP-VPSAFSDQSRCLIAQ 2465
Query: 419 ETP--GPSYSSSEQVHVTMSSLLNTSDSSDEELVTGGATSQIQGVQTNDDLNNDSDDSSD 476
TP G SS V T TS + D G + GV +D + +
Sbjct: 2466 TTPVAGSQSLSSGAVATT------TSSAGDHN---GMLSVPAPGVPHSDVGEPPASTGAQ 2516
Query: 477 NCVIVGFVKPLAERTPELVELSSDSEDLGSYEKMETVKTQEQEQSYSSGDS-----DVSR 531
+ ++P ER SS S S + + S S G S +V+
Sbjct: 2517 QPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVAL 2576
Query: 532 CSSPHSVLGKDEQINKGHCDSSTRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRH 591
P E + +G T K K+ S+S SS + +SS S +
Sbjct: 2577 KRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2636
Query: 592 RKRGRSRSSDSRSQSRSGHDQKNHRKHHGKKRMKSKRSRSRESSRP----RGRR------ 641
S SS S Q + KK +R RSR +P R R
Sbjct: 2637 SSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGER-RSRSPRKPIDSLRDSRSLSYSP 2695
Query: 642 -DKKRSRTRDSSWSRRSQTLSLSSESTSRSRSRSSDHGKRR 681
+++R + S ++S + S R SRS H +RR
Sbjct: 2696 VERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRR 2736
Score = 33.5 bits (75), Expect = 1.1
Identities = 63/259 (24%), Positives = 97/259 (37%), Gaps = 18/259 (6%)
Query: 490 RTPELVELSSDSEDLGSYEKMETVKTQEQEQSYSSGDSDVSRCSSPHSVLGKDEQINKGH 549
RTP+ S S + K ++ +Q + +S SS + SR SS S +
Sbjct: 716 RTPQRRGRSGSSSE----RKNKSRTSQRRSRSNSSPEMKKSRISSRRS---------RSL 762
Query: 550 CDSSTRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRSQSRSG 609
++ KS+ +RS S SSP S R + + + + R+ SRS S
Sbjct: 763 SSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPP 822
Query: 610 HDQKNHRKHHGKKRMKSKRSRSRESSRPR-GRRDKKRSRTRDSSWSRRS-QTLSLSSEST 667
QK+ S + + + PR G ++ + + RRS S E
Sbjct: 823 PKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELK 882
Query: 668 SRSRSRSSDHGKR--RSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRDGYESSYRRRTL 725
SR+ SR S G R +S R + + K + R + G S R
Sbjct: 883 SRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVT 942
Query: 726 SRAHYSR-QSSSPEFRVQS 743
SR R +S SP V+S
Sbjct: 943 SRTTPRRSRSVSPCSNVES 961
Score = 31.6 bits (70), Expect = 4.1
Identities = 29/132 (21%), Positives = 46/132 (34%), Gaps = 10/132 (7%)
Query: 811 QPSREFASKAKDSHYQKSSSKLDGNYKNESDTFSDSRSSDRETKH--------KRRKRKT 862
QP++E S + S SSS + + S + S S SSD E +R
Sbjct: 2525 QPAKERRSSSSSS--SSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSP 2582
Query: 863 RSLSVEIVYEGKATDTTKHHKKKKKKHKKKHKKHHGDNASRSPVVITIDSDSDKDSEVKE 922
E V EG+ + T +K++ ++S S + S S S
Sbjct: 2583 TPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2642
Query: 923 DTECDNSGPQDP 934
+ + P P
Sbjct: 2643 SSSSSSPSPAKP 2654
Score = 31.2 bits (69), Expect = 5.3
Identities = 41/154 (26%), Positives = 56/154 (36%), Gaps = 16/154 (10%)
Query: 498 SSDSEDLGSYEKMETVKTQEQEQSYSSGDSDVSRCSSPHSVLGKDEQINKGHCDSSTRIK 557
SS S S + + S SS S S SSP + + K ++ K
Sbjct: 2612 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPK----PASPKK 2667
Query: 558 SKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRSQSRSGHDQKNHRK 617
E+RS S PR S+R R S Y+ R+R S S DQ++
Sbjct: 2668 PPPGERRSRS---PRKPIDSLRDSRSLS-YSPVERRRP--------SPQPSPRDQQSSSS 2715
Query: 618 HHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDS 651
G +R + SRS R R + R R S
Sbjct: 2716 ERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSS 2749
>gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens]
Length = 320
Score = 75.9 bits (185), Expect = 2e-13
Identities = 67/199 (33%), Positives = 92/199 (46%), Gaps = 28/199 (14%)
Query: 504 LGSYEKMETVKTQEQEQSYSSGDSDVSRCSSPHSVLGKDEQINKGHCDSSTRIKSKKEEK 563
+G ++ V+ +E E D D+S+ D ++K + D+S S K++
Sbjct: 139 VGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKS 198
Query: 564 RSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRSQSRSGHDQKNHRKHHGKKR 623
S S R+ +S R SP + R R R RSRSS S SQSRS
Sbjct: 199 NRRSRSKSRSSHSR-SSSRSSSPSSSRSRSRSRSRSSSS-SQSRS--------------- 241
Query: 624 MKSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTLSLSSES----TSRSRSRSSDHG- 678
RS SRE SR RG + + SR+ S S R ++ S SS S RSRSRSS G
Sbjct: 242 ----RSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGD 297
Query: 679 --KRRSRSRNRDRYYLRNN 695
KRR+RSR+ + + N
Sbjct: 298 RKKRRTRSRSPESQVIGEN 316
Score = 55.5 bits (132), Expect = 3e-07
Identities = 78/284 (27%), Positives = 109/284 (38%), Gaps = 63/284 (22%)
Query: 491 TPELVELSSDSEDLGSYEKMETVKTQEQEQSYSSGDSDVSRCSSPHSVLGKDEQINKGHC 550
TP+ +L + G + + E V+ E+E+S D G+ ++ +G
Sbjct: 90 TPKYAKLEERTGYGGGFNERENVEYIEREESDGEYDE-----------FGRKKKKYRGKA 138
Query: 551 DSSTRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRSQSRSGH 610
I + E+K S D S Y K D S+
Sbjct: 139 VGPASILKEVEDKESEGEEEDE--------DEDLSKY-----KLDEDEDEDDADLSKYNL 185
Query: 611 DQKNHRKHHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTLSLSSESTSRS 670
D + KK + RS+SR S RS +R SS S SS S SRS
Sbjct: 186 DASEEEDSNKKKSNRRSRSKSRSSH--------SRSSSRSSSPS--------SSRSRSRS 229
Query: 671 RSRSSDHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRDGYESSYRRRTLSRAHY 730
RSRSS + RSRS +R+R R GS+ SR+ R SS R + Y
Sbjct: 230 RSRSSSSSQSRSRSSSRERSRSR---GSK--------SRSSSRSHRGSSSPR----KRSY 274
Query: 731 SRQSSSPEFRVQSFSERTNARKKNNHSERKYYYYERHRSRSLSS 774
S SSSPE +R+ +R ++ +K R RSRS S
Sbjct: 275 SSSSSSPERN----RKRSRSRSSSSGDRKK----RRTRSRSPES 310
Score = 47.8 bits (112), Expect = 5e-05
Identities = 51/169 (30%), Positives = 73/169 (43%), Gaps = 39/169 (23%)
Query: 708 SRNKDRDGYESSYRRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSERKYYYYERH 767
S +D + +S+ R R+ SR+ +SR SS R + S R R
Sbjct: 188 SEEEDSNKKKSNRRSRSKSRSSHSRSSS---------------RSSSPSSSRS-----RS 227
Query: 768 RSRSLSSNRSRTASTGTDRVRNEKPGGKRKYKTRHLEGTNEVAQPSREFASKAKDSHYQK 827
RSRS SS+ S++ S + R R+ G K + +R G +S + Y
Sbjct: 228 RSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRG-----------SSSPRKRSYSS 276
Query: 828 SSSKLDGNYKNESDTFSDSRSSDRETKHKRRKRKTRSLSVEIVYEGKAT 876
SSS + N K S SRSS + R+KR+TRS S E G+ T
Sbjct: 277 SSSSPERNRKR-----SRSRSS---SSGDRKKRRTRSRSPESQVIGENT 317
Score = 32.0 bits (71), Expect = 3.1
Identities = 41/176 (23%), Positives = 68/176 (38%), Gaps = 29/176 (16%)
Query: 453 GATSQIQGVQTNDDLNNDSDDSSDNCVIVGFVKPLAERTPELVELSSDSEDLGSYEKMET 512
G S ++ V+ + + D+ D + K + + +LS + D E
Sbjct: 140 GPASILKEVEDKESEGEEEDEDED----LSKYKLDEDEDEDDADLSKYNLDASEEEDSNK 195
Query: 513 VKT--QEQEQSYSSGDSDVSRCSSPHSVLGKDEQINKGHCDSSTRIKSKKEEKRSTSLSS 570
K+ + + +S SS SR SSP S + ++ S +R +S E+ + S
Sbjct: 196 KKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSK 255
Query: 571 PRNLNSSVRGD-----RVYS-----PYNHRHRKRGRS-------------RSSDSR 603
R+ + S RG R YS P +R R R RS RS +S+
Sbjct: 256 SRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPESQ 311
Score = 31.6 bits (70), Expect = 4.1
Identities = 36/218 (16%), Positives = 83/218 (38%), Gaps = 13/218 (5%)
Query: 693 RNNYGSRY-KWEYTYYSRNKDRDGYESSYRRRTLSRAHYSRQSSSPEFRVQSFSERTNAR 751
R YG + + E Y ++ DG + R+ + Y ++ P ++ ++ +
Sbjct: 99 RTGYGGGFNERENVEYIEREESDGEYDEFGRK---KKKYRGKAVGPASILKEVEDKESEG 155
Query: 752 KKNNHSER-KYYYYERHRSRSLSSNRSRTASTGTDRVRNEKPGGKR---KYKTRHLEGTN 807
++ + E Y + + + N+K +R K ++ H ++
Sbjct: 156 EEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSS 215
Query: 808 EVAQPSREFASKAKDSHYQKSSSKLDGNYKNESDTFSDSRSSDRETKHKRRKRKTRSLSV 867
+ PS +S+++ +SSS ++ S S SR S +++ R + S
Sbjct: 216 RSSSPS---SSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGS--KSRSSSRSHRGSSSPR 270
Query: 868 EIVYEGKATDTTKHHKKKKKKHKKKHKKHHGDNASRSP 905
+ Y ++ ++ K+ + + + SRSP
Sbjct: 271 KRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSP 308
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 75.1 bits (183), Expect = 3e-13
Identities = 113/532 (21%), Positives = 184/532 (34%), Gaps = 33/532 (6%)
Query: 427 SSEQVHVTMSSLLNTSDSSDEELVTGGATSQIQGVQTNDDLNNDSDDSSDNCVIVGFVKP 486
SS+ + + SS + SDSSD + +S ++D ++DS +SSD+
Sbjct: 554 SSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSD------- 606
Query: 487 LAERTPELVELSSDSEDLGSYEKMETVKTQEQEQSYSSGDSDV-SRCSSPHSVLGKDEQI 545
SSDS D K+ + S DSD S S +S D
Sbjct: 607 -----------SSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSD 655
Query: 546 NKGHCDSSTRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRSQ 605
+ +SS S S S SS + NSS D S + S SDS
Sbjct: 656 SSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDS 715
Query: 606 SRSGHDQKNHRKHHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTLSLSSE 665
S S + + + S S S + DSS S S S SS+
Sbjct: 716 SDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSD 775
Query: 666 STSRSRSRSSDHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRDGYESSYRRRTL 725
S+ S S S+ S S + N+ S + + S + D D SS +
Sbjct: 776 SSDSSNSSDSNDSSNSSDSSDSS-----NSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSS 830
Query: 726 SRAHYSRQSSSPEFRVQS------FSERTNARKKNNHSERKYYYYERHRSRSLSSNRSRT 779
+ S S S + S S R+++ ++ S+ S S SN S
Sbjct: 831 DSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSN 890
Query: 780 ASTGTDRVRNEKPGGKRKYKTRHLEGTNEVAQPSREFASKAKDSHYQKSSSKLDGNYKNE 839
+S +D N + + S E ++ + +S+ SS+ D + ++
Sbjct: 891 SSDSSDS-SNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSD 949
Query: 840 SDTFSDSRSSDRETKHKRRKRKTRSLSVEIVYEGKATDTTKHHKKKKKKHKKKHKKHHGD 899
S SDS +S + S S + ++D++ + D
Sbjct: 950 SSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSS-DSSDSSDSSDSSNSSDSSD 1008
Query: 900 NASRSPVVITIDSDSDKDSEVKEDTECDNSGPQDPLQNEFLAPSLEPFETKD 951
++ S + DS + DS D+ D+S D + + S + + D
Sbjct: 1009 SSDSSDSSNSSDSSNSSDSSNSSDSS-DSSDSSDSSDSSDSSDSSDSSNSSD 1059
Score = 70.9 bits (172), Expect = 6e-12
Identities = 118/554 (21%), Positives = 196/554 (35%), Gaps = 53/554 (9%)
Query: 380 SYEEGSHSDSSVITISPDEAETQELDINVATVSQAPWDDETPGPSYSSSEQVHVTMSS-L 438
S + + SDS+ + S D +++ + + + D + S +SS+ + + SS
Sbjct: 776 SSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDS 835
Query: 439 LNTSDSSDEELVTGGATSQIQGVQTNDDLNNDSDDSSDNCVIVGFVKPLAERTPELVELS 498
N+SDSSD + G+ S +++ ++DS DSSD+ + + + S
Sbjct: 836 SNSSDSSDSSDSSDGSDSDSSN-RSDSSNSSDSSDSSDS-----------SNSSDSSDSS 883
Query: 499 SDSEDLGSYEKMETVKTQEQEQSYSSGDSDVSRCS-SPHSVLGKDEQINKGHCDSSTRIK 557
+E S + ++ + + + S SS SD S S S S + N DSS
Sbjct: 884 DSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSD 943
Query: 558 SKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSR--SQSRSGHDQKNH 615
S S S S + +SS D S + S SSDS S S D N
Sbjct: 944 SSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNS 1003
Query: 616 RKHHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTLSLSSESTSRSRSR-- 673
+ S S+ S + DSS S S S SS+S++ S S
Sbjct: 1004 SDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDS 1063
Query: 674 --------SSDHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRDGYESSYRRRTL 725
SSD S + D N+ S + + S + D S
Sbjct: 1064 SDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1123
Query: 726 SRAHYSRQSSSPEFRVQSFSERTNARKKNNHSERKYYYYERHRSRSLSSNRSRTASTGTD 785
S + S SS S S+ +++ + ++ S+ S S S+ S +S +D
Sbjct: 1124 SDSSDSSDSSDSSDSSNS-SDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSD 1182
Query: 786 RVRNEKPGGKRKYKTRHLEGTNEVAQPSREFASKAKDSHYQKSSSKLDGNYKNESDTFSD 845
+ + + S + + + S SS D N ++S SD
Sbjct: 1183 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSD 1242
Query: 846 SRSSDRETKHKRRKRKTRSLSVEIVYEGKATDTTKHHKKKKKKHKKKHKKHHGDNASRSP 905
S S + ++D++ + + K +G+N
Sbjct: 1243 SSDSSNSSD-----------------SSDSSDSSDSTSDSNDESDSQSKSGNGNNNG--- 1282
Query: 906 VVITIDSDSDKDSE 919
SDSD DSE
Sbjct: 1283 ------SDSDSDSE 1290
Score = 63.9 bits (154), Expect = 7e-10
Identities = 121/596 (20%), Positives = 210/596 (35%), Gaps = 49/596 (8%)
Query: 364 NMAAFDQHANYDCPAPSYEEGS---HSDSSVITISPDEAETQELDINVATVSQAPWDDET 420
N+ + N + P E G+ HS++ + S D ++ + D DE+
Sbjct: 413 NVKTQGEVVNIEGPGQKSEPGNKVGHSNTGSDSNS-DGYDSYDFDDKSMQGDDPNSSDES 471
Query: 421 PGPSYSSSEQVHVTMSSLLNTSDSSDEELVTGGATSQIQGVQTNDDLNNDSDDSSDNCVI 480
G ++SE + SS + S +SDE G S +G + ++DSD +SD
Sbjct: 472 NGNDDANSESDN-NSSSRGDASYNSDESKDNGNG-SDSKGAE-----DDDSDSTSDTN-- 522
Query: 481 VGFVKPLAERTPELVELSSDSEDLGSYEKMETVKTQEQEQSYSSGDSDVSRCSSPHSVLG 540
+SDS G+ + K+ + S DSD S S+
Sbjct: 523 -----------------NSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSD 565
Query: 541 KDEQINKGHCDSSTRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSS 600
+ + SS S + S+ S + NSS D S + S+S
Sbjct: 566 SSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSD 625
Query: 601 DSRSQSRSGHDQKNHRKHHGKKRMKSKRSRSRESSRPRGRRDKK-RSRTRDSSWSRRSQT 659
S+S+S S S S S +SS D S + DSS S S
Sbjct: 626 SSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSN 685
Query: 660 LSLSSESTSRSRSRSSDHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDR--DGYE 717
S SS+S+ S S S S S + D N+ S + S + D +
Sbjct: 686 SSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSD 745
Query: 718 SSYRRRTLSRAHYSRQSSSPEFRVQS----FSERTNARKKNNHSERKYYYYERHRSRSLS 773
SS + + S S+S + S S+ +N+ N+ S + S S +
Sbjct: 746 SSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSN 805
Query: 774 SNRSRTASTGTDRVRNEKPGGKRKYKTRHLEGTNEVAQPS-------REFASKAKDSHYQ 826
S+ S +S +D + + +++ + S + ++++ S+
Sbjct: 806 SSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSS 865
Query: 827 KSSSKLDGNYKNESDTFSDSRSSDRETKHKRRKRKTRSLSVEIVYEGKATDTTKHHKKKK 886
SS D + ++S SDS S + + S S + ++D++ +
Sbjct: 866 DSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSE 925
Query: 887 KKHKKKH-----KKHHGDNASRSPVVITIDSDSDKDSEVKEDTECDNSGPQDPLQN 937
+ + + D++ S + DS + DS D+ NS N
Sbjct: 926 SSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSN 981
Score = 62.8 bits (151), Expect = 2e-09
Identities = 107/487 (21%), Positives = 173/487 (35%), Gaps = 30/487 (6%)
Query: 382 EEGSHSDSSVITISPDEAETQELDINVATVSQAPWDDETPGPSYSSSEQVHVTMSSLLNT 441
+ + SDSS + S D + + D + ++ S D ++ S SS+ S N+
Sbjct: 819 DSSNSSDSSNSSDSSDSSNSS--DSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNS 876
Query: 442 SDSSDEELVTGGATSQIQGVQTN--DDLNNDSDDSSDNCVIVGFVKPLAERTPELVELSS 499
SDSSD + S +N D ++DS +SSD+ + + + E S+
Sbjct: 877 SDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSD--------SSNSSDSSESSN 928
Query: 500 DSEDLGSYEKMETVKTQEQEQSYSSGDSDVSRCSSPHSVLGKDEQINKGHCDSSTRIKSK 559
S++ S + + + + S SS SD S S + + + DSS S
Sbjct: 929 SSDNSNSSDSSNS--SDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSS 986
Query: 560 KEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRSQSRSGHDQKNHRKHH 619
S S S + NSS D S + S S + S S D +
Sbjct: 987 DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSS 1046
Query: 620 GKKRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTLSLSSEST----SRSRSRSS 675
+ S S S + DSS S S S SS S+ S S SS
Sbjct: 1047 DSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSS 1106
Query: 676 DHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKD-RDGYESSYRRRTLSRAHYSRQS 734
D S + D ++ S + + S + D D ESS + + S S
Sbjct: 1107 DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSS 1166
Query: 735 SSPEFRVQS----------FSERTNARKKNNHSERKYYYYERHRSRSLSSNRSRTASTGT 784
S + S S+ +++ ++ S+ S S S+ S +S +
Sbjct: 1167 DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1226
Query: 785 DRVRNEKPGGKRKYKTRHLEGTNEVAQPSREFASKAKDSHYQKSSSKLDGNYKNE-SDTF 843
D + + + + S + + DS+ + S GN N SD+
Sbjct: 1227 DSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSD 1286
Query: 844 SDSRSSD 850
SDS SD
Sbjct: 1287 SDSEGSD 1293
Score = 58.9 bits (141), Expect = 2e-08
Identities = 81/338 (23%), Positives = 126/338 (37%), Gaps = 23/338 (6%)
Query: 361 SPFNMAAFDQHANYDCPAPSYEEGSHSDSSVITISPDEAETQELDINVATVSQAPWDDET 420
S N + +N + S + SDSS + S D +++ + ++ S D
Sbjct: 969 SDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD-----SSDSSNSSDSSN 1023
Query: 421 PGPSYSSSEQVHVTMSSLLNTSDSSDEELVTGGATSQIQGVQTNDDLNNDSDDSSDNCVI 480
S +SS+ + SS ++SDSSD + + S ++ ++DS DSSD+
Sbjct: 1024 SSDSSNSSDSSDSSDSS--DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD- 1080
Query: 481 VGFVKPLAERTPELVELSSDSEDLGSYEKMETVKTQEQEQSYSSGDSDVSRCSSPHSVLG 540
+ + + + S+ S+ S + ++ + + S S DS S SS S
Sbjct: 1081 -------SSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD-S 1132
Query: 541 KDEQINKGHCDSSTRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSS 600
D + DSS +S S S S + +SS D S + S S
Sbjct: 1133 SDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1192
Query: 601 DSRSQSRSGHDQKNHRKHHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTL 660
S S D + S S S + DSS S S
Sbjct: 1193 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDS 1252
Query: 661 SLSSESTSRSRSRSSDHGKRRSRSRNRDRYYLRNNYGS 698
S SS+S S S S S+D +S+S N NN GS
Sbjct: 1253 SDSSDS-SDSTSDSNDESDSQSKSGN------GNNNGS 1283
Score = 32.7 bits (73), Expect = 1.8
Identities = 78/411 (18%), Positives = 137/411 (33%), Gaps = 89/411 (21%)
Query: 595 GRSRSSDSRSQSRSGHDQKNHRKHHGKKRMKSKRSRSRESSRPRGRRD-------KKRSR 647
G + S + S+ + G D H K + S S+E P G+ D K S+
Sbjct: 268 GNGKDSSNNSKGQEGQD---HGKEDDHDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSK 324
Query: 648 TRDSS-------WSRR---SQTLS----------LSSESTSRSRSRSSDHGKR----RSR 683
+ ++S S+R +Q L+ ++ ES + + +S D G S
Sbjct: 325 SEENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESETHAVGKSQDKGIEIKGPSSG 384
Query: 684 SRNRDRYYLRNNYGSRYKWE---------------------------------YTYYSRN 710
+RN + + N G K + ++ +
Sbjct: 385 NRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSEPGNKVGHSNTGSD 444
Query: 711 KDRDGYESSYRRRTLSRAHYSRQSSSPEFRVQS-FSERTNARKKNNHSERKYYYYERHRS 769
+ DGY+S S Q P +S ++ N+ NN S R Y S
Sbjct: 445 SNSDGYDS------YDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDES 498
Query: 770 RSLSS-----------NRSRTASTGTDRVRNEKPGGKRKYKTRHLEGTNEVAQPSREFAS 818
+ + + S + + +D N G K+ +G ++ + +S
Sbjct: 499 KDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSS 558
Query: 819 KAKDSHYQKSSSKLDGNYKNESDTFSDSRSSDRETKHKRRKRKTRSLSVEIVYEGKATDT 878
+ DS S D N ++SD+ SDS SSD + S + +
Sbjct: 559 NSSDSSDSSDSDSSDSNSSSDSDS-SDSDSSDSSDSDSSDSSNSSDSSDS---SDSSDSS 614
Query: 879 TKHHKKKKKKHKKKHKKHHGDNASRSPVVITIDSDSDKDSEVKEDTECDNS 929
K K + D+ S+S + SDS +S+ + + NS
Sbjct: 615 DSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNS 665
>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
Length = 1462
Score = 75.1 bits (183), Expect = 3e-13
Identities = 122/523 (23%), Positives = 204/523 (39%), Gaps = 76/523 (14%)
Query: 553 STRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRK---RGRSRSSDSRSQSRSG 609
ST + +E S+S R NS YS Y+ R + R RSRSS SRS SRS
Sbjct: 648 STYSLANIKETGSSSSYHKREKNSE-SDQSTYSKYSDRSSESSPRSRSRSSRSRSYSRSY 706
Query: 610 HDQKNHRKHHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTLSLSSESTSR 669
++ H + R S RS SR + S SR S S+SS+ R
Sbjct: 707 TRSRSLASSHSRSRSPSSRSHSR------------NKYSDHSQCSRSSSYTSISSDDGRR 754
Query: 670 SRSRSSDHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRDGYESSY--RRRTLSR 727
++ R GK+ S S + + S K ++ Y + +DR Y R +L
Sbjct: 755 AKRRLRSSGKKNSVSH-------KKHSSSSEKTLHSKYVKGRDRSSCVRKYSESRSSLDY 807
Query: 728 AHYSRQS------SSPEFRVQSFSERTNARKKNNHSERKYYYYE---RHRSRSLSSNRSR 778
+ S QS S+ E Q ERT+ +++ N E K + R+L N S
Sbjct: 808 SSDSEQSSVQATQSAQEKEKQGQMERTHNKQEKNRGEEKSKSERECPHSKKRTLKENLSD 867
Query: 779 TASTGTDRVRNEKPGG-------------KRKYKTRHLEGTNEVAQPSREFASKAKDSHY 825
G+ R G K H E + + + S+ + H
Sbjct: 868 HLRNGSKPKRKNYAGSKWDSESNSERDVTKNSKNDSHPSSDKEEGEATSDSESEVSEIHI 927
Query: 826 Q-----KSSSKL-----DGNYKN--ESDTFSDSRSSDRETKHKRRKRKTRSLSVEIVYEG 873
+ KSS+ +G +K+ + + SDS S +++ R K + +
Sbjct: 928 KVKPTTKSSTNTSLPDDNGAWKSSKQRTSTSDSEGSCSNSENNRGKPQKHK------HGS 981
Query: 874 KATDTTKHHKKKKKKHK-KKHKKHHGDNASRSPVVITIDSDSDKDSEVKEDTECDNSGPQ 932
K +H KK K+K K KK KKH ++ + +E+ E D+
Sbjct: 982 KENLKREHTKKVKEKLKGKKDKKHKAPKRKQA-----FHWQPPLEFGEEEEEEIDDKQVT 1036
Query: 933 DPLQNEFLAPSLEPFETKDVVTIEAEFGVLDKECDIATLSNNLNNANKTVD--NIPPLAA 990
+ + ++ + E + + T ++ L + D T+S++L+ K +I P A
Sbjct: 1037 QESKEKKVSENNETIKDNILKTEKSSEEDLSGKHDTVTVSSDLDQFTKDDSKLSISPTAL 1096
Query: 991 SVEQTLDVREESTFVSDLENQPSNIVS-LQTEPSRQLPSPRTS 1032
+ E+ + + V E+ P+ + LQT+ + ++ +P S
Sbjct: 1097 NTEENVACLQNIQHVE--ESVPNGVEDVLQTDDNMEICTPDRS 1137
Score = 71.2 bits (173), Expect = 5e-12
Identities = 99/412 (24%), Positives = 155/412 (37%), Gaps = 61/412 (14%)
Query: 551 DSSTRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRG---RSRS-------S 600
DSS KEE + P + +GD++ P + R +R RSRS S
Sbjct: 357 DSSETPPHWKEEMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERSLSQRSRSWSYNGYYS 416
Query: 601 DSRSQSRSGHDQKNHRKHHGKKRMKSKRSRSRESSRPRGRRDKKR-----SRTRDSSWSR 655
D + SGH H+K +K++K K+ ++ R ++ KKR S S S
Sbjct: 417 DLSTARHSGH----HKKRRKEKKVKHKKKGKKQKHCRRHKQTKKRRILIPSDIESSKSST 472
Query: 656 RSQTLSLSSESTSRSRSRSSDHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRDG 715
R S E +SRS S SS H +R S++ + SR + +S++ R
Sbjct: 473 RRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSR-- 530
Query: 716 YESSYRRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSERKYYYYERHRSRSLSSN 775
S R RT S++ +S S R A K + + + ++ L +
Sbjct: 531 --GSSRSRTASKSSSHSRSRSKSRSSSKSGHRKRASKSPRKTASQLSENKPVKTEPLRAT 588
Query: 776 RSRTASTGTDRVRNE----------------KPGGK-----------RKYKTRHLEGTNE 808
++ + V E KPG K K KT HL
Sbjct: 589 MAQNENVVVQPVVAENIPVIPLSDSPPPSRWKPGQKPWKPSYERIQEMKAKTTHL----- 643
Query: 809 VAQPSREFASKAKDSHYQKSSSKLDGNYKNESDTFSDSRSSDR--ETKHKRRKRKTRSLS 866
P + S A SSS +ESD + S+ SDR E+ + R R +RS S
Sbjct: 644 --LPIQSTYSLANIKETGSSSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRS 701
Query: 867 VEIVYEGKATDTTKHHKKKKKKHKKKHKKHHGDNA--SRSPVVITIDSDSDK 916
Y + + H + + + + + D++ SRS +I SD +
Sbjct: 702 YSRSYTRSRSLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGR 753
Score = 68.9 bits (167), Expect = 2e-11
Identities = 108/515 (20%), Positives = 189/515 (36%), Gaps = 87/515 (16%)
Query: 491 TPELVELSSDSEDLGSYEKMETVKTQEQE---------QSYSSGDSDVSRCSSPH----- 536
TP S+S+D S E K + Q + +S GD CSS
Sbjct: 343 TPPRSRSCSESDDDDSSETPPHWKEEMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERSL 402
Query: 537 SVLGKDEQINKGHCDSSTRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGR 596
S + N + D ST S +KR + + +G + H+ K+ R
Sbjct: 403 SQRSRSWSYNGYYSDLSTARHSGHHKKRRKE----KKVKHKKKGKKQKHCRRHKQTKKRR 458
Query: 597 ---------SRSSDSRSQSRSGHDQKNHRK----HHGKKRMKSKRSRSRESSRPRGRRDK 643
S+SS R +S ++ + HH KR SK + +SS RD
Sbjct: 459 ILIPSDIESSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDS 518
Query: 644 KRSRTRDSSWSRRSQTLSLSSESTSRSRSRS-------SDHGKRRSRSRNRDRYYLRNNY 696
RS++ S+SR S +S+S+S SRSRS S H KR S+S + L N
Sbjct: 519 YRSKSHSQSYSRGSSRSRTASKSSSHSRSRSKSRSSSKSGHRKRASKSPRKTASQLSENK 578
Query: 697 GSRYKWEYTYYSRNKD----------------------------RDGYESSYRRRTLSRA 728
+ + ++N++ + ++ SY R +A
Sbjct: 579 PVKTEPLRATMAQNENVVVQPVVAENIPVIPLSDSPPPSRWKPGQKPWKPSYERIQEMKA 638
Query: 729 HYSR----QSSSPEFRVQSFSERTNARKKNNHSERKYYYYERHRSRSL-SSNRSRTASTG 783
+ QS+ ++ ++ K+ +SE Y ++ RS SS RSR+ S+
Sbjct: 639 KTTHLLPIQSTYSLANIKETGSSSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRSSR 698
Query: 784 TDRVRNEKPGGKRKYKTRHLEGTNEVAQPSREFASKAKDSHYQKSSSKLDGNYKNESDTF 843
+ R Y + + + SR S++ S + D + + S ++
Sbjct: 699 S-----------RSYSRSYTRSRSLASSHSR---SRSPSSRSHSRNKYSDHSQCSRSSSY 744
Query: 844 SDSRSSDRETKHKRRKRKTRSLSVEIVYEGKATDTTKHHKKKKKKHKKKHKKHHGDNASR 903
+ S D +R + + SV +++ T H K K + + + + + SR
Sbjct: 745 TSISSDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVKGRDRSSCVRKYSE--SR 802
Query: 904 SPVVITIDSDSDKDSEVKEDTECDNSGPQDPLQNE 938
S + + DS+ + E + G + N+
Sbjct: 803 SSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNK 837
Score = 68.2 bits (165), Expect = 4e-11
Identities = 65/200 (32%), Positives = 90/200 (45%), Gaps = 19/200 (9%)
Query: 561 EEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRSQSRSGHDQKNHRKHHG 620
+E R T+ + R N D + + R SRS S+S+++S H ++ H
Sbjct: 1279 DEVRKTARLNRRPRNQESSSDEQTPSRDDDSQSRSPSRSR-SKSETKSRHRTRSVSYSHS 1337
Query: 621 KKRMKSKRS--RSRESSRPRGRRDKKRSRTRDSSWSRRSQTLSLSSESTSRSRSRSSDHG 678
+ R +S S RSR SR R R R RTR S S RS S ++SRSRSRSS +
Sbjct: 1338 RSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYRSYK---SHRTSSRSRSRSSSYD 1394
Query: 679 KR-RSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRDGYESSYRRRTLSRAHYSRQSSSP 737
RSRS D YY R+ SR S+ D SY RR+ S Y S S
Sbjct: 1395 PHSRSRSYTYDSYYSRSRSRSR--------SQRSDSYHRGRSYNRRSRSCRSYGSDSESD 1446
Query: 738 EFRVQSFSERTNARKKNNHS 757
+S+S + + + +S
Sbjct: 1447 ----RSYSHHRSPSESSRYS 1462
Score = 55.5 bits (132), Expect = 3e-07
Identities = 88/404 (21%), Positives = 150/404 (37%), Gaps = 39/404 (9%)
Query: 514 KTQEQEQSYSSGDSDVSRCSSPHSVLGKDEQINKGHCDSSTRIKSKKEEKRSTSLSSPRN 573
K E S SS +S S SS S L + + H +SKK K ++S PRN
Sbjct: 191 KPTHSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRSKKRRKEASSSEEPRN 250
Query: 574 LNSSVRGDRVYSPYNHRHRK-RGRSRSSDSRSQSRSGHDQKNHRKHHGKKRMKSKRSRSR 632
++ +P H R RS DS ++ + + R +R
Sbjct: 251 KHA-------MNPKGHSERSDTNEKRSVDSSAKREKPVVRPEEIPPVPENRFLLRRDMPV 303
Query: 633 ESSRPRGR--------RDKKRSRTRDSSWSRRSQTLSLSSESTSRSRSRSSDHGKRRSRS 684
++ P + D+K S ++ + T+ + SRS S S D +
Sbjct: 304 VTAEPEPKIPDVAPIVSDQKPSVSKSGRKIKGRGTIRYHTPPRSRSCSESDDDDSSETPP 363
Query: 685 RNRDRYYLRNNY--GSRYKWEYTYYSRNKDRDGYESSYRRRTLSRAHYSRQSSSPEFRVQ 742
++ Y S KW +K D S + R+LS+ SR S +
Sbjct: 364 HWKEEMQRLRAYRPPSGEKWS----KGDKLSDPCSSRWDERSLSQR--SRSWSYNGY--- 414
Query: 743 SFSERTNARKKNNHSERKYYYYERHRSRSLSSNRSRT-ASTGTDRVRNEKPGGKRKYKTR 801
+S+ + AR +H +R+ +H+ + R T R+ K TR
Sbjct: 415 -YSDLSTARHSGHHKKRRKEKKVKHKKKGKKQKHCRRHKQTKKRRILIPSDIESSKSSTR 473
Query: 802 HLEGTNEVAQPSREFASKAKDSHYQKSSSKLDGNYKNESDTFSDSRSSDRETKHKRRKRK 861
++ + + + SR S + SH+ SSK D + K++ D S S R++ + +
Sbjct: 474 RMKSSCDRERSSR---SSSLSSHH---SSKRDWS-KSDKDVQSSLTHSSRDSYRSKSHSQ 526
Query: 862 TRSLSVEIVYEGKATDTTKHHKKKKKKHKKKHKKHHGDNASRSP 905
+ S + + H + + K + K H AS+SP
Sbjct: 527 SYSRGSS---RSRTASKSSSHSRSRSKSRSSSKSGHRKRASKSP 567
Score = 52.4 bits (124), Expect = 2e-06
Identities = 56/209 (26%), Positives = 86/209 (41%), Gaps = 27/209 (12%)
Query: 630 RSRESSRPRGRRDKKRS------RTRDSSWSRRSQTLSLSSESTSRSRSRSSDHGKRRSR 683
+S+ RP D+ R R R+ S QT S +S SRS SRS K ++
Sbjct: 1267 KSKNKVRPGSLFDEVRKTARLNRRPRNQESSSDEQTPSRDDDSQSRSPSRS--RSKSETK 1324
Query: 684 SRNRDRYYLRNNYGSRYK-----WEYTYYSRNKDRDGYESSYRRRTLSRAHYSRQSSSPE 738
SR+R R ++ SR + + YSR++ R Y R SR SS
Sbjct: 1325 SRHRTRSVSYSHSRSRSRSSTSSYRSRSYSRSRSRGWYSRGRTR--------SRSSSYRS 1376
Query: 739 FRVQSFSERTNARKK--NNHSERKYYYYERHRSRSLSSNRSRTASTGTDRVRNEKPGGKR 796
++ S R+ +R + HS + Y Y+ + SRS RSR+ S +D + +R
Sbjct: 1377 YKSHRTSSRSRSRSSSYDPHSRSRSYTYDSYYSRS----RSRSRSQRSDSYHRGRSYNRR 1432
Query: 797 KYKTRHLEGTNEVAQPSREFASKAKDSHY 825
R +E + S ++ S Y
Sbjct: 1433 SRSCRSYGSDSESDRSYSHHRSPSESSRY 1461
Score = 49.3 bits (116), Expect = 2e-05
Identities = 84/386 (21%), Positives = 148/386 (38%), Gaps = 70/386 (18%)
Query: 555 RIKSKKEEKRSTSLSSPRNLNSSVRGDR-VYSPYNHRHRKRGRSRSSDSRSQSRSGHDQK 613
+I++ K + S + R ++ V + + + + +K S SDS S S S +
Sbjct: 152 QIENLKTDAASRPYADVRVIDCGVLATKSIKDVFEKKRKKPTHSEGSDSSSNSSSSSESS 211
Query: 614 NHRK--HHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTLSLSSESTSRSR 671
+ + H +R K KR RP+ +R KKR + SS R++ +
Sbjct: 212 SESELEHERSRRRKHKR-------RPKVKRSKKRRKEASSSEEPRNK-----HAMNPKGH 259
Query: 672 SRSSDHGKRRS--RSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRDGYESSYRRRTLSRAH 729
S SD ++RS S R++ +R E N R L R
Sbjct: 260 SERSDTNEKRSVDSSAKREKPVVRPE-------EIPPVPEN------------RFLLRRD 300
Query: 730 YSRQSSSPEFRVQSFSERTNARKKN-NHSERKYYYYERHRSRSLSSNRSRTASTGTDRVR 788
++ PE ++ + + +K + + S RK R R + RSR+ S D
Sbjct: 301 MPVVTAEPEPKIPDVAPIVSDQKPSVSKSGRK--IKGRGTIRYHTPPRSRSCSESDDDDS 358
Query: 789 NEKPGGKRKYKTRHLEGTNEVAQPSREFASKAK------DSHYQKSSSKLDGNYKNESDT 842
+E P + ++ PS E SK S + + S + +
Sbjct: 359 SETP----PHWKEEMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERSLSQRSRSWSYNGY 414
Query: 843 FSDSRSSDRETKHKRRKRKTRSLSVEIVYEGKATDTTKHHKK-KKKKHKKKHKKHHGDNA 901
+SD ++ HK+R+++ + KH KK KK+KH ++HK+
Sbjct: 415 YSDLSTARHSGHHKKRRKEKK---------------VKHKKKGKKQKHCRRHKQ-----T 454
Query: 902 SRSPVVITIDSDSDKDSEVKEDTECD 927
+ ++I D +S K S + + CD
Sbjct: 455 KKRRILIPSDIESSKSSTRRMKSSCD 480
Score = 45.1 bits (105), Expect = 4e-04
Identities = 53/174 (30%), Positives = 71/174 (40%), Gaps = 15/174 (8%)
Query: 508 EKMETVKTQEQEQSYSSGDSDVSRCSSPHSVLGKDEQINKGHCDSSTRIKSKKEEKRSTS 567
E +T ++ S SR S + ++ H S +R + RS S
Sbjct: 1295 ESSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSRSRSRSSTSSYRSRSYS 1354
Query: 568 LSSPRNLNSSVRGDRVYSPY----NHRHRKRGRSRSS--DSRSQSRSGHDQKNHRKHHGK 621
S R S R S Y +HR R RSRSS D S+SRS + ++ +
Sbjct: 1355 RSRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHSRSRS----YTYDSYYSR 1410
Query: 622 KRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTLSLSSESTSRSRSRSS 675
R +S+ RS S RGR +RSR S S S + S S S RS S SS
Sbjct: 1411 SRSRSRSQRS--DSYHRGRSYNRRSR---SCRSYGSDSESDRSYSHHRSPSESS 1459
Score = 35.4 bits (80), Expect = 0.28
Identities = 33/133 (24%), Positives = 57/133 (42%), Gaps = 13/133 (9%)
Query: 773 SSNRSRTASTGTDRVRNEKPGGKRKYKTRHLEGTNEVAQPSREFASKAKDSHYQKSSSKL 832
S N+ R S D VR +R R+ E +++ PSR+ S+++ +S S+
Sbjct: 1268 SKNKVRPGSL-FDEVRKTARLNRRP---RNQESSSDEQTPSRDDDSQSRSPSRSRSKSET 1323
Query: 833 DGNYKNESDTFSDSRSSDRETKHKRRKRK-TRSLSVEIVYEGKATDTTKHHKKKKKKHKK 891
++ S ++S SRS R + R R +RS S G+ + + +
Sbjct: 1324 KSRHRTRSVSYSHSRSRSRSSTSSYRSRSYSRSRSRGWYSRGRT--------RSRSSSYR 1375
Query: 892 KHKKHHGDNASRS 904
+K H + SRS
Sbjct: 1376 SYKSHRTSSRSRS 1388
Score = 32.0 bits (71), Expect = 3.1
Identities = 34/136 (25%), Positives = 55/136 (40%), Gaps = 18/136 (13%)
Query: 826 QKSSSKLDGNYKNESDTFSDSRSSDRETKH---KRRKRKTRSLSVEIVYEGKATDTTKHH 882
+K + +G+ + + + S SS+ E +H +RRK K R K +++
Sbjct: 189 RKKPTHSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRSKKRRKEASSSEEP 248
Query: 883 KKKKKKHKKKHKKHHGDNASRSPVVITIDSDSDKDSEVKEDTECDNSGPQDPLQNEFLAP 942
+ K + K H + N RS +DS + ++ V E P P +N FL
Sbjct: 249 RNKHAMNPKGHSERSDTNEKRS-----VDSSAKREKPVVRPEEI----PPVP-ENRFLLR 298
Query: 943 SLEPFETKDVVTIEAE 958
P VVT E E
Sbjct: 299 RDMP-----VVTAEPE 309
>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
Length = 434
Score = 74.3 bits (181), Expect = 5e-13
Identities = 74/253 (29%), Positives = 104/253 (41%), Gaps = 42/253 (16%)
Query: 558 SKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRSQSRSGHDQKNHRK 617
SK RS S S R S G + S + +R S+ S+ H+ K H
Sbjct: 36 SKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSS 95
Query: 618 HHGKKRM---------------KSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTLSL 662
G++R+ KS R RS SR R RR + RSR R S SR +
Sbjct: 96 DKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRER--- 152
Query: 663 SSESTSRSRSRS-----SDHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRDGYE 717
+S SRSR R S KRR RSR+R R R+ SR + +R++ RD +
Sbjct: 153 -KKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSR------TRSRSRDRKK 205
Query: 718 SSYRRRTLSRAHYSRQSSSPEFR-------VQSFSERTNARKKNNHSERKYYYYERHRSR 770
+ R SR+ SR S P FR Q R R K +R+ E+ + +
Sbjct: 206 RIEKPRRFSRS-LSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQ 264
Query: 771 SLSSNRSRTASTG 783
+++ A+TG
Sbjct: 265 EIAA----AAATG 273
Score = 67.4 bits (163), Expect = 7e-11
Identities = 72/242 (29%), Positives = 101/242 (41%), Gaps = 57/242 (23%)
Query: 557 KSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSDS-----RSQSRSGHD 611
+ KK+E+ S+S + + R R R R R R SD+ RS+SRS
Sbjct: 20 RDKKKEQSEVSVSPRASKHHYSRS---------RSRSRERKRKSDNEGRKHRSRSRSKEG 70
Query: 612 QKNHRKHHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTLSLSSESTSRSR 671
+++ K K+ KS+ +E S +GR S + R+ + SS S SR
Sbjct: 71 RRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERK---SSRGRSHSR 127
Query: 672 SRSSDHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRDGYESSYRRRTLSRAHYS 731
SRS + RR RSR+R+R R SR+++R S R R SR+
Sbjct: 128 SRSRE---RRHRSRSRERKKSR--------------SRSRERKKSRSRSRERKKSRS--- 167
Query: 732 RQSSSPEFRVQSFSERTNARKKNNHSERKYYYYERHRSRSLSSNRSRTASTGTDR-VRNE 790
R+ RK+ S + RHR+RS RSRT S DR R E
Sbjct: 168 ---------------RSRERKRRIRSRSRSRSRHRHRTRS----RSRTRSRSRDRKKRIE 208
Query: 791 KP 792
KP
Sbjct: 209 KP 210
Score = 62.4 bits (150), Expect = 2e-09
Identities = 61/226 (26%), Positives = 99/226 (43%), Gaps = 27/226 (11%)
Query: 641 RDKKRSRTRDSSWSRRSQTLSLSSESTSRSRSRSSDHGKRRSRSRNRDRYYLRNNYGSRY 700
RDKK+ ++ S R S+ S S SR R R SD+ R+ RSR+R + R+ +
Sbjct: 20 RDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKS 79
Query: 701 KWEYTYYSRNKDRDGYESSYRRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSERK 760
++ N D SS + R R + S R + S R + ++ ER+
Sbjct: 80 SKKHKSEEHN---DKEHSSDKGR--ERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERR 134
Query: 761 YYYYERHRSRSLSSNRSRTASTGTDRVRNEKPGGKRKYKTRHLEGTNEVAQPSREFASKA 820
+ R R +S S +R R S R R +K ++R E + SR S++
Sbjct: 135 HRSRSRERKKSRSRSRERKKSRSRSRER-------KKSRSRSRERKRRIRSRSR---SRS 184
Query: 821 KDSHYQKSSSKLDGNYKNESDTFSDSRSSDRETKHKRRKRKTRSLS 866
+ H +S S+ + SRS DR+ + ++ +R +RSLS
Sbjct: 185 RHRHRTRSRSR------------TRSRSRDRKKRIEKPRRFSRSLS 218
Score = 52.0 bits (123), Expect = 3e-06
Identities = 46/174 (26%), Positives = 77/174 (44%), Gaps = 6/174 (3%)
Query: 514 KTQEQEQSYSSGDSDVSRCSSPHSVLGKDEQINKGHCDSSTRI--KSKKEEKRSTSLSSP 571
K++E S D R +S + G+D K S R +S+ E+R S S
Sbjct: 84 KSEEHNDKEHSSDKGRERLNSSEN--GEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRE 141
Query: 572 RNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRSQSRSGHDQKNHRKHHGKKRMKSK-RSR 630
R + S +R S R RK+ RSRS + + + RS ++ +H + R +++ RSR
Sbjct: 142 RKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSR 201
Query: 631 SRESSRPRGRR-DKKRSRTRDSSWSRRSQTLSLSSESTSRSRSRSSDHGKRRSR 683
R+ + RR + SRT R T + E+ +R R+ ++R +
Sbjct: 202 DRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREK 255
Score = 51.2 bits (121), Expect = 5e-06
Identities = 49/168 (29%), Positives = 74/168 (44%), Gaps = 6/168 (3%)
Query: 514 KTQEQEQSYSSGDSDVSRCSSPHSVLGKDEQINKGHCDSSTRIKSKKEEKRSTSLSSPRN 573
+++E + S S S H+ K+ +KG ++ + KR SS
Sbjct: 66 RSKEGRRHESKDKSSKKHKSEEHN--DKEHSSDKGRERLNSSENGEDRHKRKERKSSRGR 123
Query: 574 LNSSVRGDRVYSPYNHRHRKRGRSRSSD-SRSQSRSGHDQKNHRKHHGKKRMKSKRSRSR 632
+S R R RK+ RSRS + +S+SRS +K+ + +KR RSRSR
Sbjct: 124 SHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSR 183
Query: 633 ESSRPRGR-RDKKRSRTRDSSWSRRSQTLSLSSESTSRSRSRSSDHGK 679
R R R R + RSR+RD +R + S S SR+ S G+
Sbjct: 184 SRHRHRTRSRSRTRSRSRDR--KKRIEKPRRFSRSLSRTPSPPPFRGR 229
Score = 48.5 bits (114), Expect = 3e-05
Identities = 50/205 (24%), Positives = 86/205 (41%), Gaps = 37/205 (18%)
Query: 703 EYTYYSRNKDRDGYESSYRRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSERKYY 762
E T R+K ++ E S R S+ HYSR S R+ RK+ + +E + +
Sbjct: 14 EKTSPDRDKKKEQSEVSVSPRA-SKHHYSRSRS-----------RSRERKRKSDNEGRKH 61
Query: 763 YYERHRSRSLSSNRSRTASTGTDRVRNEKPGGKRKYKTRHLEGTNEVAQPSREFASKAKD 822
R RSRS R + + + ++E+ K + E N + +D
Sbjct: 62 ---RSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNS--------SENGED 110
Query: 823 SHYQKSSSKLDGNYKNESDTFSDSRSSDRETKHK---RRKRKTRSLSVEIVYEGKATDTT 879
H +K G S SRS RE +H+ R ++K+RS S E K+ +
Sbjct: 111 RHKRKERKSSRGR--------SHSRSRSRERRHRSRSRERKKSRSRSRE---RKKSRSRS 159
Query: 880 KHHKKKKKKHKKKHKKHHGDNASRS 904
+ KK + + +++ ++ + SRS
Sbjct: 160 RERKKSRSRSRERKRRIRSRSRSRS 184
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 73.9 bits (180), Expect = 7e-13
Identities = 62/192 (32%), Positives = 92/192 (47%), Gaps = 20/192 (10%)
Query: 588 NHRHRKRGRSRS-SDSRSQSRSGHDQKNHRKHHGKKRMKSKRSRSRESSRPRGR---RDK 643
+ +RKR SR S SRS+SRS D+++ KR +RSRSR+ R R R RDK
Sbjct: 5 SRHYRKRSASRGRSGSRSRSRSPSDKRS-------KRGDDRRSRSRDRDRRRERSRSRDK 57
Query: 644 KRSRTRDSSWSRRSQTLSLSSESTSRSRSRSSDHGKRRSRSRNRDRYYLRNNYGSR-YKW 702
+RSR+RD RRS++ SR R RS +RRSRSR+R R ++ G++ K
Sbjct: 58 RRSRSRDRKRLRRSRS---RERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKT 114
Query: 703 EYTYYSRNKDRDGYESSYRRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSERKYY 762
E S+ K G S +++ ++ + F E RK ER
Sbjct: 115 ENRSRSKEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRK-----ERVEK 169
Query: 763 YYERHRSRSLSS 774
+ E R +++ +
Sbjct: 170 WREEQRKKAMEN 181
Score = 65.1 bits (157), Expect = 3e-10
Identities = 80/357 (22%), Positives = 142/357 (39%), Gaps = 48/357 (13%)
Query: 609 GHDQKNHRKHHGKKRMKSKRSRSRESSRPRGRR-DKKRSRTRDSSWSRRSQTLSLSSEST 667
G + +++RK + RSRSR S R +R D +RSR+RD R S S
Sbjct: 2 GRESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRER------SRSR 55
Query: 668 SRSRSRSSDHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRDGYESSYRRRTLSR 727
+ RSRS D KR RSR+R+R R+++R S RRR+ SR
Sbjct: 56 DKRRSRSRDR-KRLRRSRSRER------------------DRSRERRRSRSRDRRRSRSR 96
Query: 728 AHYSR-QSSSPEFRVQSFSERTNARKKNNHSERKYYYYERHRSRSLSSNRSRTASTGTDR 786
+ R +SSSP + + R+ +++K + E E+ + + + + D+
Sbjct: 97 SRGRRSRSSSPGNKSKKTENRSRSKEKTDGGESS---KEKKKDKDDKEDEKEKDAGNFDQ 153
Query: 787 VRNEKPGGKRKYKTRHLEGTNEVAQPSREFASKAKDS--HYQKSSSKLDGNYKNESDTFS 844
+ E+ KRK V + E KA ++ +K ++ K +
Sbjct: 154 NKLEEEMRKRK---------ERVEKWREEQRKKAMENIGELKKEIEEMKQGKKWSLEDDD 204
Query: 845 DSRSSDRETKHKRRKRKTRSLSVEIVYEGKATDTTKHHKKKKKKHKKKHKKHHGDNASRS 904
D E + + + + L Y + + K + K ++K G ++
Sbjct: 205 DDEDDPAEAEKEGNEMEGEELDPLDAYMEEVKEEVKKFNMRSVKGGGGNEKKSGPTVTKV 264
Query: 905 PVVIT-----IDSDSDKDSEVKEDTECDNSGPQDPLQNEFLAPSLEPFETKDVVTIE 956
V+T +DSD K ++ D + ++ + L +L ++TK +E
Sbjct: 265 VTVVTTKKAVVDSDKKKGELMENDQDAMEYSSEE--EEVDLQTALTGYQTKQRKLLE 319
Score = 37.4 bits (85), Expect = 0.074
Identities = 37/166 (22%), Positives = 63/166 (37%), Gaps = 6/166 (3%)
Query: 524 SGDSDVSRCSSPHSVLGKDEQINKGHCDSSTRIKSKKEEKRSTSLSSPRNLNSSVRGDRV 583
SG SR S D++ ++ R +S+ +KR + + L S +R
Sbjct: 18 SGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERD 77
Query: 584 YSPYNHRHRKRGRSRSSDSRSQSRSGHDQKNHRKHHGKKRMKSKRSRSRESSRPRGRRDK 643
S R R R R R SRS+SR + + + KK RSRS+E + G K
Sbjct: 78 RSRERRRSRSRDRRR---SRSRSRGRRSRSSSPGNKSKK--TENRSRSKEKT-DGGESSK 131
Query: 644 KRSRTRDSSWSRRSQTLSLSSESTSRSRSRSSDHGKRRSRSRNRDR 689
++ + +D + + ++ R + R R +
Sbjct: 132 EKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKK 177
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 72.4 bits (176), Expect = 2e-12
Identities = 97/477 (20%), Positives = 169/477 (35%), Gaps = 67/477 (14%)
Query: 452 GGATSQIQGVQTNDDLNNDSDDSSDNCVIVGFVKPLAERTPELVELSSDSEDLGSYEKME 511
G SQI +N + ++ + S P +R PE + D S+E+
Sbjct: 577 GSRGSQIDSHSSNSNYHDSWETRSSY--------PERDRYPE--RDNRDQARDSSFERRH 626
Query: 512 TVKTQEQEQSYSSGDSDVSRCSSPHSVLGKDEQINKGHCDSSTRIKSKKEEKRSTSLSSP 571
+ + + S R + L +DE+ + D + ++ +R
Sbjct: 627 GERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERD 686
Query: 572 RNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRSQSRSGHDQKNHRKHHGKKRMKSKRSRS 631
R +R R +R R+R + + ++ R H ++ + +R R
Sbjct: 687 RERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDRE 746
Query: 632 RESSRPRGRRDKKRSRTRDSSWSRRSQTLSLSSESTSRSRSRSSDHGKRRSRSRNRDRYY 691
+E R R R+++R R R+ R R R + + R + R R R
Sbjct: 747 KEREREREERERERERERE----------------RERERERERERARERDKERERQR-- 788
Query: 692 LRNNYGSRYKWEYTYYSRNKDRDGYESSYRRRTLSRAHYSRQSSSPEFRVQSFSERTNAR 751
WE R+ R+ E R H R+S S S R + +
Sbjct: 789 ---------DWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPK 839
Query: 752 KKNNHSERKYYY------YERHR----------SRSLSSNRSRTASTGTDRVRNEKPGGK 795
++ HS Y E+HR SRSLS + G + + KP K
Sbjct: 840 RRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERK 899
Query: 796 ---RKYKTRHLEGTNEVAQPSREFASKAKDSHYQKSSSKLDGNYKNESDTFSDSRSSDRE 852
R+Y+ + L+ RE + S + + + G++++E SD + +
Sbjct: 900 ESSRRYEEQELKEKVSSVDKQREQTEILESSRMR--AQDIIGHHQSEDRETSDRAHDENK 957
Query: 853 TKHKRRKRKTRSLSVEIV-YEGKATDTTKH--------HKKKKKKHKKKHKKHHGDN 900
K K +K+ + + V E +TT +KKK +KK KK GD+
Sbjct: 958 KKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKKSKGDS 1014
Score = 67.4 bits (163), Expect = 7e-11
Identities = 115/565 (20%), Positives = 203/565 (35%), Gaps = 88/565 (15%)
Query: 420 TPGPSYSSSEQVHVTMSSLLNTSDSSDEELVTGGATSQIQGVQTNDDLNNDSDDSSDNCV 479
+P PS S + SS +S +S ++ T +S + Q N N
Sbjct: 207 SPSPSLRKSSKSPKRKSSP-KSSSASKKDRKTSAVSSPLLDQQRNSKTNQS--------- 256
Query: 480 IVGFVKPLAERTPELVELSSDSEDLGS-YEKMETVKTQEQEQSYSSGDS----------- 527
K RTP + LG Y++ VK + +E++ D
Sbjct: 257 -----KKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDRGRDFERQREKR 311
Query: 528 DVSRCSSP----HSVLGKDEQINKGHCDSSTRIKSKK-EEKRSTSLSSPRNLNSSVRGDR 582
D R +SP HS + + SS + S KR+ S S R L +R R
Sbjct: 312 DKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLR--R 369
Query: 583 VYSPYNHRHRKRGRSRSSDSRSQS----RSGHDQKNHRKHHGKKRMKSKRSRSRESSRPR 638
SPY S SS R QS RS +K H + +R RE +R
Sbjct: 370 SASPYP------SHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTR-- 421
Query: 639 GRRDKKRSRTRDSSWSRRSQTLSLSSESTSRSRSRSSDHGKRRSRSRNRDRYYLRNNYGS 698
G+RD+++ + + + SS R D RR RDR LR++
Sbjct: 422 GKRDREKDSREEREYEQDQ-----SSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDM 476
Query: 699 RYKWEYTYYSRN-------------------KDRDGYESSYRR-------RTLSRAHYSR 732
R E YSR+ +DR+G ++ + R+ R H
Sbjct: 477 RDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLRE 536
Query: 733 QSSSPEFRVQSFSERTNARKKNNHSERKYYYYERHRSRSLSSNRSRTASTGTDRVRNEKP 792
+SS E R +S +E + + + + E S S S+ S ++ ++
Sbjct: 537 ESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSW 596
Query: 793 GGKRKYKTRHLEGTNEVAQPSREFASKAKDSHYQKSSSKLDGNYKNESDTFSDS----RS 848
+ Y R P R+ +A+DS +++ + D E D S +
Sbjct: 597 ETRSSYPERD-------RYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQG 649
Query: 849 SDRETKHKRRKRKTRSLSVEIVYEGKATDTTKHHKKKKKKHKKKHKKHHGDNASRSPVVI 908
+ E + R+ + R V+ + +A + + ++ +++ +++ ++ + +
Sbjct: 650 RNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELER 709
Query: 909 TIDSDSDKDSEVKEDTECDNSGPQD 933
+ +++ E + D E D D
Sbjct: 710 ERAREREREREKERDRERDRDRDHD 734
Score = 55.5 bits (132), Expect = 3e-07
Identities = 93/381 (24%), Positives = 148/381 (38%), Gaps = 77/381 (20%)
Query: 561 EEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRSQSRSGHDQKNHRKHHG 620
++KRS+SL S R+ +R GR RS + S RSG DQ G
Sbjct: 1185 DQKRSSSLGSNRS---------------NRSHTSGRLRSPSNDSAHRSGDDQS------G 1223
Query: 621 KKRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTLSLSSESTSRSRSRSSDHGKR 680
+KR+ SR RE ++ +++SR +R + S STS R S H R
Sbjct: 1224 RKRVLHSGSRDREKTKSLEITGERKSRI---DQLKRGE----PSRSTSSDRQDSRSHSSR 1276
Query: 681 RSRSRNRDRYYLRN-NYGSRYKWEYTYYSRNKDRDGYESSYRRRTLSRAHYSRQSSSPEF 739
RS + + + R+ ++ SR R ++RD YE R R R ++ +
Sbjct: 1277 RSSPESDRQVHSRSGSFDSR--------DRLQERDRYEHD-RERERERRDTRQREWDRDA 1327
Query: 740 RVQSFSERTNARKKNNHSERKYYYYERHRSRSLSSNRSRTASTGTDRVRNEKPGGKRKYK 799
R R + ER ER + R L R R S +R R+
Sbjct: 1328 DKDWPRNRDRDRLRERERER-----ERDKRRDLDRERERLISDSVERDRDR--------- 1373
Query: 800 TRHLEGTNEVAQPSREFASKAKDSHYQKSSSKLDGNYKNESDTFS-DSRSSDRETKHKRR 858
R F S +S ++ +KL+G ++ + ++ S DS + D+E K
Sbjct: 1374 -----------DRDRTFESSQIES-VKRCEAKLEGEHERDLESTSRDSLALDKERMDKDL 1421
Query: 859 KRKTRSLSVEIVYEGKATDTTKHHKKKKKKHKKKHKKHHGDNASRSPVVITIDSDSDK-- 916
SV+ E ++ T+ + + K G A I+ D + D+
Sbjct: 1422 G------SVQGFEETNKSERTESLEAGDDESKLDDAHSLGSGAGEGYEPIS-DDELDEIL 1474
Query: 917 --DSEVKEDTECDNSGPQDPL 935
D+E +ED + + P DPL
Sbjct: 1475 AGDAEKREDQQDEEKMP-DPL 1494
>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
Length = 484
Score = 72.0 bits (175), Expect = 3e-12
Identities = 63/240 (26%), Positives = 105/240 (43%), Gaps = 26/240 (10%)
Query: 596 RSRSSDSRSQSRSGHDQKNHRKHHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSR 655
R R + S + D+K ++ H + R +S+R R+ SSR R R + R R+ S SR
Sbjct: 225 RVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSR 284
Query: 656 RSQTLSLSSESTSRSRSRSSDHGKR-RSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRD 714
R S+S R RS S + G+R RS S+ RD+ +Y + + R
Sbjct: 285 R------RSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRS 338
Query: 715 GYESSYRRRTLSRAHYSRQSSSPEFRV-QSFSERTNARKKNNHSERKYYYYERHRSRSLS 773
RRR+ S ++ SP+ ++ +S S R + ++K +++ ER RS S
Sbjct: 339 ASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTS-- 396
Query: 774 SNRSRTASTGTDRVRNEKPGGKRKYKTRHLEGTNEVAQPSREFASKAK--DSHYQKSSSK 831
+ +K K K + R E +V Q +R++ + + DS +K K
Sbjct: 397 --------------KKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEK 442
Score = 70.1 bits (170), Expect = 1e-11
Identities = 76/286 (26%), Positives = 119/286 (41%), Gaps = 50/286 (17%)
Query: 559 KKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRSQSRSGHDQKNHRKH 618
KKEEKR R+ S R R +P + RHR+ SRS+SR +++H K
Sbjct: 241 KKEEKR-------RHSRSRSRSRRRRTPSSSRHRR--------SRSRSR----RRSHSKS 281
Query: 619 HGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTLSLS---SESTSRSRSRSS 675
++R KS R R R SR RGRR + S+TRD + + S + S ST+R RSRS+
Sbjct: 282 RSRRRSKSPRRR-RSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTAR-RSRSA 339
Query: 676 DHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRDGYESSYRRRTLSRAHYSRQSS 735
+RR RSR+ R S K R R + R ++
Sbjct: 340 SRERRRRRSRSGTR------------------SPKKPRSPKRKLSRSPSPRRHKKEKKKD 381
Query: 736 SPEFRVQSFSERTNARKKNNHSERKYYYYERHRSRSLSSNRSRTASTGTDRVRNEKPGGK 795
+ R + ER+ ++KK + ++ + R S + T E+ G
Sbjct: 382 KDKERSRDERERSTSKKKKSK--------DKEKDRERKSESDKDVKQVTRDYDEEEQGYD 433
Query: 796 RKYKTRHLEGTNEVAQPSREFASKAKDSHYQKSSSKLDGNYKNESD 841
+ + + + E P + S K + SK++G+ +E D
Sbjct: 434 SEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNGDDHHEED 479
Score = 59.7 bits (143), Expect = 1e-08
Identities = 81/314 (25%), Positives = 127/314 (40%), Gaps = 54/314 (17%)
Query: 611 DQKNHRKHHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTLSLSSESTSRS 670
D + KR++ +S + P ++++KR +R S SRR +T S
Sbjct: 213 DTSSKEIEEAMKRVREAQSLISAAIEP-DKKEEKRRHSRSRSRSRRRRTPS--------- 262
Query: 671 RSRSSDHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRDGYESSYRRRTLSRAHY 730
SS H + RSRSR R +S+++ R +S RRR+ SR
Sbjct: 263 ---SSRHRRSRSRSRRRS------------------HSKSRSRRRSKSPRRRRSHSRERG 301
Query: 731 SRQSSSPEFRVQSFSERTNARKKNNHSERKYYYYERHRSRSLSSNRSRTASTGTDRVRNE 790
R S+ + R + ++ + KK + + K Y R RSRS S R R S R +
Sbjct: 302 RRSRSTSKTRDK---KKEDKEKKRSKTPPKSYSTAR-RSRSASRERRRRRSRSGTRSPKK 357
Query: 791 KPGGKRKYKTRHLEGTNEVAQPSREFASKAKDSHYQKSSSKLDGNYKNESDTFSDSRSSD 850
KRK + P R K KD ++S + E T +S D
Sbjct: 358 PRSPKRK--------LSRSPSPRRHKKEKKKDKDKERSRD------ERERSTSKKKKSKD 403
Query: 851 RETKHKRRKRKTRS-LSVEIVYEGKATDTTKHHKKKKKKHKKKHKKHHGDNASRSPVVIT 909
+E K R+RK+ S V+ V + + +K+KK +KK G ++ V
Sbjct: 404 KE---KDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKK-PIETGSPKTKECSVEK 459
Query: 910 IDSDSDKDSEVKED 923
DS ++S+V D
Sbjct: 460 GTGDSLRESKVNGD 473
Score = 59.3 bits (142), Expect = 2e-08
Identities = 49/182 (26%), Positives = 79/182 (43%), Gaps = 9/182 (4%)
Query: 746 ERTNARKKNNHSERKYYYYERHRSRSLSSNRSRTASTGTDRVRNEKPGGKRKYKTRHLEG 805
+R ++R ++ R+ RHR RS S +R R+ S R R++ P +R +
Sbjct: 245 KRRHSRSRSRSRRRRTPSSSRHR-RSRSRSRRRSHSKSRSRRRSKSPRRRRSH------- 296
Query: 806 TNEVAQPSREFASKAKDSHYQKSSSKLDGNYKNESDTFSDSRSSDRETKHKRRKRKTRSL 865
+ E + SR SK +D + K T SRS+ RE + +R + TRS
Sbjct: 297 SRERGRRSRS-TSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSP 355
Query: 866 SVEIVYEGKATDTTKHHKKKKKKHKKKHKKHHGDNASRSPVVITIDSDSDKDSEVKEDTE 925
+ K + + + KK+K K K K+ D RS D +KD E K +++
Sbjct: 356 KKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESD 415
Query: 926 CD 927
D
Sbjct: 416 KD 417
Score = 45.1 bits (105), Expect = 4e-04
Identities = 28/117 (23%), Positives = 52/117 (44%), Gaps = 1/117 (0%)
Query: 543 EQINKGHCDSSTRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSDS 602
E+ + S TR K K+++++ S + P++ S+ R R S R R R +RS
Sbjct: 299 ERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSY-STARRSRSASRERRRRRSRSGTRSPKK 357
Query: 603 RSQSRSGHDQKNHRKHHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQT 659
+ + + H K++ K K R R KK+S+ ++ R+S++
Sbjct: 358 PRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSES 414
Score = 39.7 bits (91), Expect = 0.015
Identities = 55/232 (23%), Positives = 88/232 (37%), Gaps = 35/232 (15%)
Query: 473 DSSDNCVIVGFVKPLAERTPELVELSSDSEDLGSYEKMETVKTQ----EQEQSYSSGDSD 528
D N V G V P + E+ + + + + + + E+++ +S S
Sbjct: 195 DPKLNHVAAGLVSPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSR 254
Query: 529 VSRCSSPHSVLGKDEQINKGHCDSSTRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYN 588
R +P S + + S R SK +R + R +S RG R S
Sbjct: 255 SRRRRTPSS-----SRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSK 309
Query: 589 HRHRKRG-----------RSRSSDSRSQSRSGHDQKNHRKHHGKKRMKSKRSRSRESSR- 636
R +K+ +S S+ RS+S S +++ R G + K RS R+ SR
Sbjct: 310 TRDKKKEDKEKKRSKTPPKSYSTARRSRSAS-RERRRRRSRSGTRSPKKPRSPKRKLSRS 368
Query: 637 PRGRR---------DKKRSRTRDSSWSRRSQTLSLSSESTSRSRSRSSDHGK 679
P RR DK+RSR RS + S+ + R R S+ K
Sbjct: 369 PSPRRHKKEKKKDKDKERSRDE----RERSTSKKKKSKDKEKDRERKSESDK 416
>gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo
sapiens]
Length = 375
Score = 71.6 bits (174), Expect = 4e-12
Identities = 51/139 (36%), Positives = 75/139 (53%), Gaps = 15/139 (10%)
Query: 552 SSTRIKSKKE-EKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRSQSRSGH 610
SS + KS++ +K +S LNSS G+ RH+++ R +SS RS SRS
Sbjct: 20 SSKKHKSEEHNDKEHSSDKGRERLNSSENGE-------DRHKRKER-KSSRGRSHSRSRS 71
Query: 611 DQKNHRKHHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTLSLSSESTSRS 670
++ HR +++ RSR R+ SR R R ++K+SR+R RR + S S SRS
Sbjct: 72 RERRHRSRSRERKKSRSRSRERKKSRSRSR-ERKKSRSRSRERKRR-----IRSRSRSRS 125
Query: 671 RSRSSDHGKRRSRSRNRDR 689
R R + R+RSR+RDR
Sbjct: 126 RHRHRTRSRSRTRSRSRDR 144
Score = 68.2 bits (165), Expect = 4e-11
Identities = 65/228 (28%), Positives = 97/228 (42%), Gaps = 33/228 (14%)
Query: 568 LSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRSQSRSGHDQKNHRKHHGKKRMKSK 627
L R S + + + H ++ + + + S +G D+ H +K KS
Sbjct: 8 LKQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDR------HKRKERKSS 61
Query: 628 RSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTLSLSSESTSRSRSRS-----SDHGKRRS 682
R RS SR R RR + RSR R S SR + +S SRSR R S KRR
Sbjct: 62 RGRSHSRSRSRERRHRSRSRERKKSRSRSRER----KKSRSRSRERKKSRSRSRERKRRI 117
Query: 683 RSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRDGYESSYRRRTLSRAHYSRQSSSPEFR-- 740
RSR+R R R+ SR + +R++ RD + + R SR+ SR S P FR
Sbjct: 118 RSRSRSRSRHRHRTRSRSR------TRSRSRDRKKRIEKPRRFSRS-LSRTPSPPPFRGR 170
Query: 741 -----VQSFSERTNARKKNNHSERKYYYYERHRSRSLSSNRSRTASTG 783
Q R R K +R+ E+ + + +++ A+TG
Sbjct: 171 NTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQEIAA----AAATG 214
Score = 62.8 bits (151), Expect = 2e-09
Identities = 77/336 (22%), Positives = 127/336 (37%), Gaps = 46/336 (13%)
Query: 593 KRGRSRSSDSRSQSRSGHDQKNHRKHHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDSS 652
+R S+ S+ H+ K H G++R+ S + R + + RS +R S
Sbjct: 12 RRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRS 71
Query: 653 WSRRSQTLSLSSESTSRSRSRSSDHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKD 712
RR + S S R +SRS +++SRSR+R+R R+ R + R +
Sbjct: 72 RERRHR-----SRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKR-------RIRS 119
Query: 713 RDGYESSYRRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSERKYYYYERHRSRSL 772
R S +R RT SR SR S R+ RKK R++ SRSL
Sbjct: 120 RSRSRSRHRHRTRSR---SRTRS-----------RSRDRKKRIEKPRRF-------SRSL 158
Query: 773 SSNRSRTASTGTDRVRNEKPGGKRKYKTRHLEGTNEVAQPSREFASKAKDSHYQKSSSKL 832
SRT S R RN + R Q +E K K +++
Sbjct: 159 ----SRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQEI-AAAAAT 213
Query: 833 DGNYKNESDTFSDSRS-------SDRETKHKRRKRKTRSLSVEIVYEGKATDTTKHHKKK 885
G+ N + + + + + + ++V Y A + K +++
Sbjct: 214 GGSVLNVAALLASGTQVTPQIAMAAQMAALQAKALAETGIAVPSYYNPAAVNPMKFAEQE 273
Query: 886 KKKHKKKHKKHHGDNASRSPVVITIDSDSDKDSEVK 921
KK+ K GD + + + ++ +KD VK
Sbjct: 274 KKRKMLWQGKKEGDKSQSAEIWEKLNF-GNKDQNVK 308
Score = 52.0 bits (123), Expect = 3e-06
Identities = 46/174 (26%), Positives = 77/174 (44%), Gaps = 6/174 (3%)
Query: 514 KTQEQEQSYSSGDSDVSRCSSPHSVLGKDEQINKGHCDSSTRI--KSKKEEKRSTSLSSP 571
K++E S D R +S + G+D K S R +S+ E+R S S
Sbjct: 25 KSEEHNDKEHSSDKGRERLNSSEN--GEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRE 82
Query: 572 RNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRSQSRSGHDQKNHRKHHGKKRMKSK-RSR 630
R + S +R S R RK+ RSRS + + + RS ++ +H + R +++ RSR
Sbjct: 83 RKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSR 142
Query: 631 SRESSRPRGRR-DKKRSRTRDSSWSRRSQTLSLSSESTSRSRSRSSDHGKRRSR 683
R+ + RR + SRT R T + E+ +R R+ ++R +
Sbjct: 143 DRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREK 196
Score = 36.2 bits (82), Expect = 0.17
Identities = 25/100 (25%), Positives = 43/100 (43%), Gaps = 6/100 (6%)
Query: 806 TNEVAQPSREFASKAKDSHYQKSSSKLDGNYKNESDTFSDSRSSDRETKHKRRKRK-TRS 864
TN + R SK K S KS D + ++ + S + E +HKR++RK +R
Sbjct: 4 TNFFLKQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRG 63
Query: 865 LSVEIVYEGKATDTTKHHKKKKKKHKKKHKKHHGDNASRS 904
S ++ + H+ + ++ KK + SRS
Sbjct: 64 RS-----HSRSRSRERRHRSRSRERKKSRSRSRERKKSRS 98
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 71.2 bits (173), Expect = 5e-12
Identities = 99/453 (21%), Positives = 175/453 (38%), Gaps = 57/453 (12%)
Query: 505 GSYEKMETVKTQEQEQSYSSGDSDVSRCSSPHSVLGKDEQINKGHCDSSTRIKSK----- 559
GS T + +EQ S +S H+ + + Q +G + S R + +
Sbjct: 3157 GSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVS 3216
Query: 560 --------KEEKRSTSLSSPRNLNSSVRGDRVYS---PYNHRHRKRGRSRSSD------- 601
E+ S S+ RN SV+ + P +H + G S+D
Sbjct: 3217 QDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGT 3276
Query: 602 ------SRSQSRSGHDQ--KNHRKHHGKKRMKSKRSRSRESSRPRGRRDK--KRSRTRDS 651
S Q+ S H+Q + + HG + +S S SR S PRG+ + SR S
Sbjct: 3277 RHAETSSGGQAASSHEQARSSPGERHGSRHQQSADS-SRHSGIPRGQASSAVRDSRHWGS 3335
Query: 652 SWSRRSQTLSLSSESTSRSRSRSSDHGKRRSRSRN--RDRYYLRNNYGSRYKWEYTYYSR 709
S S+ S + S ES ++S S G + + RDR R+ + ++ + + +
Sbjct: 3336 SGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQ 3395
Query: 710 NKDRDGYESSYRRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSERKYYYYER--H 767
++ G + R H + SS Q + ++ R+ +YE+
Sbjct: 3396 SESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVD 3455
Query: 768 RSRSLSSNRSRTASTG-TDRVRNEKPGGKRKYKTRHLEGTNEVAQPS----REFASKAKD 822
RS S+ S T S G +D R + +TR+ E + + ++ S E +++A
Sbjct: 3456 RSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQADS 3515
Query: 823 SHYQKS---------SSKLDGNYKNESDTFSDSRSSDRETKHKRRKRKTRSLSVEIVYEG 873
S + +S +S+ G+ ++ D+ S S D E R R + E +G
Sbjct: 3516 SRHSQSGQGQSAGPRTSRNQGSSVSQ-DSDSQGHSEDSERWSGSASRNHRGSAQEQSRDG 3574
Query: 874 KATDTTKHHKKKKKKHKKKHKK----HHGDNAS 902
T+ H + H + + HH +N+S
Sbjct: 3575 SRHPTSHHEDRAGHGHSAESSRQSGTHHAENSS 3607
Score = 67.4 bits (163), Expect = 7e-11
Identities = 85/422 (20%), Positives = 154/422 (36%), Gaps = 34/422 (8%)
Query: 534 SPHSVLGKDEQINKGHCDSSTRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNH---- 589
S HS +G D+S + R T S G R + P
Sbjct: 1512 SGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSS 1571
Query: 590 RHRKRGRSRSSDSRSQSRSGHDQKNHRKHHGKKRMKSKRSRS---------RESSR---- 636
RH + G+ S+ S++ R G R G +RS S RE SR
Sbjct: 1572 RHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSR 1631
Query: 637 -PRGRRDKKRSRTRDSSWSRRS-----QTLSLSSESTSRSRSRSSDHGKRRSRSRNRDRY 690
PR ++ + S + SR+S +T S ++S+ ++RSS + SR +
Sbjct: 1632 NPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADS 1691
Query: 691 YLRNNYGSRYKWEYTYYSRNKDRDGYESS----YRRRTLSRAHYSRQSSSPEFRVQSFSE 746
+ G R S N+ G ++S + + +++ + + P + S
Sbjct: 1692 STDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQEST 1751
Query: 747 RTNARKKNNHSERKYYYYERHRSRSLSSNRSRTASTGTDRVRNEKPGGKRKYKTRHLEGT 806
R + +++ S Y H + R+ ++ G R R+E+ ++ EG
Sbjct: 1752 RGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQ-EGQ 1810
Query: 807 NEVAQPSREFASKAKDSHYQKSSSKLDGNYKNESDTFSDSRSSDRETKHKRRKRKTRSLS 866
+ + + SHY++S + + S T S RS + R ++ +
Sbjct: 1811 DTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRN 1870
Query: 867 VEIVYEGKATDTTKHHKKKKKKHKKKHK-----KHHGDNASRSP-VVITIDSDSDKDSEV 920
+ +G ++HH+ + +H + G SR+ ++ DSDS SE
Sbjct: 1871 EKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSED 1930
Query: 921 KE 922
E
Sbjct: 1931 SE 1932
Score = 66.6 bits (161), Expect = 1e-10
Identities = 88/386 (22%), Positives = 145/386 (37%), Gaps = 32/386 (8%)
Query: 561 EEKRSTSLSSPRNLNSSVRGDRVYSPYNH-RHRKRGRSRSSDSRSQSRSGHDQKNH---- 615
E RS+ S +N S + P R RKR SR S R D + H
Sbjct: 258 ERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSGSA 317
Query: 616 -RKHHGKKRMKSKRSRSRESSR-PRGRRDKKRSRTRDSSWSRRSQTLSLSSESTSRSRSR 673
R HHG S +SR+ SR PR + + S + SR+S T +E++SR ++
Sbjct: 318 SRNHHG-----SAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGT--RHAETSSRGQTA 370
Query: 674 SSDHGKRRSRSRNRDRYYLRNNYGSRYK--WEYTYYSRNKDRDGYESSYRRRTLSRAHYS 731
SS R S + ++ SR+ S DR SS + + S H
Sbjct: 371 SSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSE 430
Query: 732 RQSS-------SPEFRVQSFSERTNAR--KKNNHSERKYYYYERHRSRSLSSNRSRTAST 782
+ R QS E T R +++ S Y H + R+ T++
Sbjct: 431 NSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTG 490
Query: 783 GTDRVRNEKPGGKRKYKTRHLEGTNEVAQPSREFASKAKDSHYQKSSSKLDGNYKNESDT 842
G +E+ ++ EG + + + SH+++S ++ + + S T
Sbjct: 491 GRQGSHHEQARDSSRHSASQ-EGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHT 549
Query: 843 FSDSRSSDRETKHKRRKRKTRSLSVEIVYEGKATDTTKHHKKKKKKHKKKHK-----KHH 897
S RS + R ++ + E +G ++HH+ + +H +
Sbjct: 550 TSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSS 609
Query: 898 GDNASRSP-VVITIDSDSDKDSEVKE 922
G SR+ ++ DSDS SE E
Sbjct: 610 GPRTSRNQGSSVSQDSDSQGHSEDSE 635
Score = 60.8 bits (146), Expect = 6e-09
Identities = 128/562 (22%), Positives = 209/562 (37%), Gaps = 88/562 (15%)
Query: 386 HSDSSVITISPDEAETQELDINVATVSQAPWDDETPGPSYSSSEQVHVTMSSLLNTSDSS 445
HS S AET ++ QA +PG + S Q S T
Sbjct: 348 HSADSSRQSGTRHAETSSRGQTASSHEQAR---SSPGERHGSGHQQSADSSRHSATGRGQ 404
Query: 446 DEELVTGGATSQIQGVQTNDDLNNDSDDSSDNCVIVGFVKP-LAERTPELVELSSDSEDL 504
V+ G Q +D + ++SD + G K L +++ + E
Sbjct: 405 ASSAVSDRGHRGSSGSQASD--SEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERS 462
Query: 505 G-SYEKMETVKTQEQEQSYS--SGDS---------DVSRCSSPHSVLGKDEQINKGHCDS 552
G S + V T EQ S +G S + +R SS HS + + +GH S
Sbjct: 463 GRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGS 522
Query: 553 STRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNH-RHRKRGRSRSSDSRSQSRSGHD 611
S + ++S + S + S + S +H + R SR + + QS G
Sbjct: 523 SRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTR 582
Query: 612 QKNHRKHHGKKRMKSKRSRS---RESSRPRGRRDKKRSRTRDSSWSRRSQTLSLSSESTS 668
R H + S R +SS PR R++ S ++DS SQ S SE S
Sbjct: 583 HSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSD----SQGHSEDSERWS 638
Query: 669 RSRSRSSDHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRDGYESSYRRRTLSRA 728
S SR + HG + +SR+ GSR+ S ++DR G+ S S
Sbjct: 639 GSASR-NHHGSAQEQSRD----------GSRHP-----RSHHEDRAGHGHSADSSRKSGT 682
Query: 729 HYSRQSSSPEFRVQSFSERTNARKKNNHSERKYYYYERHRSRS--LSSNRSRTASTG--- 783
+++ SSS + ++H + + ERH SR S++ SR + TG
Sbjct: 683 RHTQNSSS-------------GQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQ 729
Query: 784 -TDRVRNEKPGGKRKYKTRHLEGTNEVAQPSREFASKAKDSHYQKS-----------SSK 831
+ VR+ G + EG +E + ++ + + H+Q+S S+
Sbjct: 730 ASSAVRDSGHRGSSGSQATDSEGHSEDSD-TQSVSGHGQAGHHQQSHQESARDRSGERSR 788
Query: 832 LDGNYKNESDTFSDSRSSD---------RETKHKRRKRKTRSLSVEIVYEGKATDTTKHH 882
G++ + T S SS R+ H + R S +G+ DT + H
Sbjct: 789 RSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSAS--QDGQ--DTIRGH 844
Query: 883 KKKKKKHKKKHKKHHGDNASRS 904
++ ++ HH + RS
Sbjct: 845 PGSSRRGRQ--GSHHEQSVDRS 864
Score = 60.5 bits (145), Expect = 8e-09
Identities = 99/470 (21%), Positives = 175/470 (37%), Gaps = 47/470 (10%)
Query: 505 GSYEKMETVKTQEQEQSYSSGDSDVSRCSSPHSVLGKDEQINKGHCDSSTRIKSK----- 559
GS T + +EQ + S +S H+ + + Q +G + S + +
Sbjct: 888 GSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVS 947
Query: 560 --------KEEKRSTSLSSPRNLNSSVRGDRVYS---PYNHRHRKRGRSRSSDSRSQSRS 608
E+ S S+ RN S + + P +H + G S+DS QS +
Sbjct: 948 QDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGT 1007
Query: 609 GHDQ--------KNHRKHHGK--KRMKSKRSRSRESSRPRG-RRDKKRSRTRD-----SS 652
H + +H + +R S+ +S +SSR G R + S RD SS
Sbjct: 1008 PHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSS 1067
Query: 653 WSRRSQTLSLSSESTSRSRSRSSDHGKRRSRSRN--RDRYYLRNNYGSRYKWEYTYYSRN 710
S+ S + S ES ++S S G + + RD R+ + ++ + + ++
Sbjct: 1068 GSQASDSEGHSEESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQS 1127
Query: 711 KDRDGYESSYRRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSERKYYYYER--HR 768
+ G + R H + SS Q + A + R+ ++E+ R
Sbjct: 1128 ESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDR 1187
Query: 769 SRSLSSNRSRTASTGTDRVRNEKPGGK------RKYKTRHLEGTNEVAQPSREFASKAKD 822
S S+ S T S G + + G + RK K + +G+ E AS A
Sbjct: 1188 SGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRKDK-QSGDGSRHSGSRHHEAASWADS 1246
Query: 823 S-HYQKSSSKLDGNYKNESDTFSDSRSSDRETKHKRRKRKTRSLSVEIVYEGKATDTTKH 881
S H Q + G+ + S S+ SD E +R + S S + G + + ++
Sbjct: 1247 SRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGSASRN--HHGSSREQSRD 1304
Query: 882 HKKKKKKHKKKHKKHHGDNASRSPVVITIDSDSDKDSEVKEDTECDNSGP 931
+ H ++ + HG +A S T ++S + E S P
Sbjct: 1305 GSRHPGFH-QEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSP 1353
Score = 59.3 bits (142), Expect = 2e-08
Identities = 78/351 (22%), Positives = 138/351 (39%), Gaps = 55/351 (15%)
Query: 511 ETVKTQEQEQSYSSGD-----SDVSRCSSPHSVLGKDEQINKGHCDSSTRIKSKKEEKRS 565
E+ + + E+S SG S + S H G + +G R S+
Sbjct: 777 ESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRH----- 831
Query: 566 TSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRSQSRSGHDQKNHRKHHGKKRMK 625
S+ ++ ++RG S +RGR S +S RSGH +H H + +
Sbjct: 832 ---SASQDGQDTIRGHPGSS-------RRGRQGSHHEQSVDRSGHSGSHH--SHTTSQGR 879
Query: 626 SKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTLSLSSESTSRSRSRSSDHGKRRSRSR 685
S SR + SR R + ++RD S S+ SS + S++ SR+
Sbjct: 880 SDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTS 939
Query: 686 NRDRYYLRNNYGSRYKWEYTYYSRNKDRDGYESSYRRRTLSRAHYSRQSSSPEFRVQSFS 745
R + + S++ D +G+ R + S + R S+ Q S
Sbjct: 940 RR---------------QGSSVSQDSDSEGHSEDSERWSGSASRNHRGSA------QEQS 978
Query: 746 ERTNARKKNNHSERKYYYYERHRSRSLSSNRSRTASTGTDRVRNEK----PGGKRKYKTR 801
+ +++H +R + + SR + + T+S G +E+ PG ++ +R
Sbjct: 979 RHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPG--ERHGSR 1036
Query: 802 HLEGTNEVAQ---PSREFASKAKDS-HYQKSSSKLDGN--YKNESDTFSDS 846
H + + P R+ +S +DS H+ S S+ + + ESDT S S
Sbjct: 1037 HQQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVS 1087
Score = 58.2 bits (139), Expect = 4e-08
Identities = 82/427 (19%), Positives = 155/427 (36%), Gaps = 44/427 (10%)
Query: 534 SPHSVLGKDEQINKGHCDSSTRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNH---- 589
S HS ++G D+S + R+T S G R + +H
Sbjct: 864 SGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADIS 923
Query: 590 RHRKRGRSRSSDSRSQSRSGH------DQKNH------------RKHHGKKRMKSKRSRS 631
RH + G+ +S SR+ R G D + H R H G S + +S
Sbjct: 924 RHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRG-----SAQEQS 978
Query: 632 RESSR-PRGRRDKKRSRTRDSSWSRRS-----QTLSLSSESTSRSRSRSSD---HGKRRS 682
R SR PR + + + SR+S +T S ++S ++RSS HG R
Sbjct: 979 RHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQ 1038
Query: 683 RSRNRDRYY-LRNNYGSRYKWEYTYYSRNKDRDGYESSYRRRTLSRAHYSRQSSSPEFRV 741
+S + R+ + S + ++ + + + + +++ P +
Sbjct: 1039 QSADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQS 1098
Query: 742 QSFSERTNARKKNNHSERKYYYYERHRSRSLSSNRSRTASTGTDRVRNEKPGGKRKYKTR 801
S R + ++ S Y H + R+RT STG + + + +
Sbjct: 1099 HQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRT-STGRRQGSHHEQARDSSRHSA 1157
Query: 802 HLEGTNEVAQPSREFASKAKDSHYQKSSSKLDGNYKNESDTFSDSRSSDRETKHKRRKRK 861
EG + + + SH+++S + + + S T S RS + R
Sbjct: 1158 SQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSAS 1217
Query: 862 TRSLSVEIVYEGKATDTTKHHKKKKKKHKKKHKKHHGDNASRSPV------VITIDSDSD 915
++ + +G ++HH+ +H + + +S S ++ DSDS+
Sbjct: 1218 RQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSE 1277
Query: 916 KDSEVKE 922
+ S+ E
Sbjct: 1278 RHSDDSE 1284
Score = 55.5 bits (132), Expect = 3e-07
Identities = 81/368 (22%), Positives = 137/368 (37%), Gaps = 44/368 (11%)
Query: 516 QEQEQSYSSGDSDVSRCSSPHSVLGKDEQINKGHCDSSTRIKSKKEEKRSTSLSSPRNLN 575
QE + +S G S R S + EQ H + T ++ + S R+
Sbjct: 1100 QESARDWSGGRS--GRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSA 1157
Query: 576 SSVRGDRVYSPYNHRHRKRGRSRSSDSRSQSRSGHDQKNHRKHHGKKRMKSKRSRSRESS 635
S D + + + R+ GR S +S RSGH +H H + +S S + S
Sbjct: 1158 SQEGQDTIRA--HPGSRRGGRQGSHHEQSVDRSGHSGSHH--SHTTSQGRSDASHGQSGS 1213
Query: 636 RPRGRRDKKRSRTRD------------SSWSRRSQTLSLSSESTSRSR---------SRS 674
R R+ +K ++ D +SW+ S+ + E +S SR S+
Sbjct: 1214 RSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQD 1273
Query: 675 SDHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRDGYESSYRRRTLSRAHYSRQS 734
SD + S RN++GS SR + RDG + +H
Sbjct: 1274 SDSERHSDDSERLSGSASRNHHGS---------SREQSRDGSRHPGFHQEDRASHGHSAD 1324
Query: 735 SSPEFRVQSFSERTNARKKNNHSERKYYYYERHRSR-SLSSNRSRTASTG----TDRVRN 789
SS + ++ + ++H + + ERH SR S++ SR + G + VR+
Sbjct: 1325 SSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRD 1384
Query: 790 EKPGGKRKYKTRHLEGTNEVAQPSREFASKAKDSHYQ---KSSSKLDGNYKNESDTFSDS 846
G + + EG +E + A H Q +S+ G S +F
Sbjct: 1385 SGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFLYQ 1444
Query: 847 RSSDRETK 854
SS +++
Sbjct: 1445 VSSHEQSE 1452
Score = 55.1 bits (131), Expect = 3e-07
Identities = 76/390 (19%), Positives = 135/390 (34%), Gaps = 44/390 (11%)
Query: 499 SDSEDLGSYEKMETVKTQEQEQSYSSGDSDVSRCSSPHSVLGKDEQINKGHCDSSTRIKS 558
SD++ + + + + QE + R S + EQ H + T
Sbjct: 3350 SDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGR 3409
Query: 559 KKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRSQSRSGHDQKNHRKH 618
++ + S R+ S D + + +RGR S +S RSGH +H
Sbjct: 3410 RQGSHHEQARDSSRHSASQEGQDTIRG--HPGSSRRGRQGSHYEQSVDRSGHSGSHH--S 3465
Query: 619 HGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDS---SWSR-------------------- 655
H + +S SR + SR R+ + ++ D SWS
Sbjct: 3466 HTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQ 3525
Query: 656 -------RSQTLSLSSESTSRSRSRSSDHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYS 708
R+Q S+S +S S+ S S+ + +R ++ GSR+ S
Sbjct: 3526 SAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHP-----TS 3580
Query: 709 RNKDRDGYESSYRRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSERKYYYYERHR 768
++DR G+ S S H++ SS Q+ S AR ++
Sbjct: 3581 HHEDRAGHGHSAESSRQSGTHHAENSSGG----QAASSHEQARSSAGERHGSHHQQSADS 3636
Query: 769 SRSLSSNRSRTASTGTDRVRNEKPGGKRKYKTRHLEGTNEVAQPSREFASKAKDSHYQKS 828
SR + +S D G + H E ++ + + A + SH + +
Sbjct: 3637 SRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQEST 3696
Query: 829 SSKLDG-NYKNESDTFSDSRSSDRETKHKR 857
+ G + ++ S + S E+ H R
Sbjct: 3697 RGRSAGRSGRSGSFLYQVSTHEQSESAHGR 3726
Score = 53.9 bits (128), Expect = 8e-07
Identities = 99/478 (20%), Positives = 174/478 (36%), Gaps = 41/478 (8%)
Query: 420 TPGPSYSSSEQVHVTMSSLLNTSDSSDEELVTGGATSQIQGVQTNDDLNNDSDDSSDNCV 479
+PG + S Q S+ T D +V G Q +D + + + +
Sbjct: 1676 SPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVS 1735
Query: 480 IVGFVKPLAERTPELVELSSDSEDLGSYEKMETVKTQEQEQSYS--SGDS---------D 528
G P + E S S + V T EQ +S +G S +
Sbjct: 1736 AHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHE 1795
Query: 529 VSRCSSPHSVLGKDEQINKGHCDSSTRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYN 588
+R SS HS + + +GH SS + ++S S + S + S +
Sbjct: 1796 QARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVS 1855
Query: 589 HRHRKRGRSRSSDSRSQSRSGHDQKNHRKHHGKK--RMKSKRSRSRESSRPRGRRDKKR- 645
RG+S S Q+R+ + +H G + S+ SR S +G+ R
Sbjct: 1856 -----RGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRT 1910
Query: 646 SRTRDSSWSRRSQTLSLSSESTSRSRSRSSDH-GKRRSRSRNRDRYYLRNNYGSRYKWEY 704
SR + SS S+ S + S +S S S S +H G +SR+ GSR+
Sbjct: 1911 SRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQSRD----------GSRHPG-- 1958
Query: 705 TYYSRNKDRDGYESSYRRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSERKYYYY 764
S ++DR G+ S S ++ SS R Q+ S AR ++
Sbjct: 1959 ---SHHEDRAGHGHSADSSRQSGTRHTESSS----RGQAASSHEQARSSAGERHGSHHQL 2011
Query: 765 E-RHRSRSLSSNRSRTASTGTDRVRNEKPGGKRKYKTRHLEGTNEVAQPSREFASKAKDS 823
+ SR + +S D G + H E ++ + ++ A + S
Sbjct: 2012 QSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQS 2071
Query: 824 HYQKSSSKLDGNYKNESDTFSDSRSSDRETKHKRRKRKTRSLSVEIVYEGKATDTTKH 881
H ++S+ G S +F S+ +++ + + + + +A D+++H
Sbjct: 2072 H-KESARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRH 2128
Score = 53.5 bits (127), Expect = 1e-06
Identities = 82/407 (20%), Positives = 142/407 (34%), Gaps = 32/407 (7%)
Query: 499 SDSEDLGSYEKMETVKTQEQEQSYSSGDSDVSRCSSPHSVLGKDEQINKGHCDSSTRIKS 558
SD++ + + K + +E + R S + EQ H S+
Sbjct: 2054 SDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGG 2113
Query: 559 KKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRG-RSRSSDSRSQSRSGHDQKNHRK 617
++ + S R+ S D + H RG R S +S RSGH +H
Sbjct: 2114 RQGSHYDQAQDSSRHSASQEGQDTIRG---HPGPSRGGRQGSHQEQSVDRSGHSGSHHSH 2170
Query: 618 HHGKKRMKSKRSRSRESSRPRGRRDKKRS----------RTRDSSWSRRSQTLSL----- 662
+ R + R +S S R DK++S SSW+ S+ +
Sbjct: 2171 TTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQS 2230
Query: 663 SSESTSRSR----SRSSDHGKRRSRSRNRDRYYLRNNYGSRYKWEYT----YYSRNKDRD 714
S TSR R S+ SD S R RN++GS + S ++DR
Sbjct: 2231 SGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRA 2290
Query: 715 GYESSYRRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSERKYYYYERHRSRSLSS 774
G+ S S H++ SS Q+ S AR ++ SR
Sbjct: 2291 GHGHSAESSRQSGTHHAENSSGG----QAASSHEQARSSAGERHGSHHQQSADSSRHSGI 2346
Query: 775 NRSRTASTGTDRVRNEKPGGKRKYKTRHLEGTNEVAQPSREFASKAKDSHYQKSSSKLDG 834
+ +S D G + H E ++ + + A + SH + + + G
Sbjct: 2347 GHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAG 2406
Query: 835 NYKNESDTFSDSRSSDRETKHKRRKRKTRSLSVEIVYEGKATDTTKH 881
S +F S+ +++ + T + + + +A D+++H
Sbjct: 2407 R-SGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRH 2452
Score = 52.0 bits (123), Expect = 3e-06
Identities = 91/441 (20%), Positives = 161/441 (36%), Gaps = 48/441 (10%)
Query: 499 SDSEDLGSYEKMETVKTQEQEQSYSSGDSDVSRCSSPHSVLGKDEQINKGHCDSSTRIKS 558
SD++ + ++ + + +E + R S + EQ H ++
Sbjct: 1405 SDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGG 1464
Query: 559 KKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRG-RSRSSDSRSQSRSGHDQKNHRK 617
++ + + +S R+ S D + H RG R S +S RSGH +H
Sbjct: 1465 RQGSRHEQARNSSRHSASQDGQDTIRG---HPGSSRGGRQGSYHEQSVDRSGHSGYHH-- 1519
Query: 618 HHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTLSLSSESTSRSRSRSSDH 677
+ P+GR D ++ S SR+++ S + + S SR +
Sbjct: 1520 ---------------SHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHEP 1564
Query: 678 GKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRDGY--ESSYRRRTLSRAHYSRQSS 735
R SR+ + + + + S+++D +G+ +S R + SR HY
Sbjct: 1565 STRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYG---- 1620
Query: 736 SPEFRVQSFSERTNARKKNNHSE-RKYYYYERHRSRSLSSNRSRTASTGTDRVRNEK--- 791
R QS R +R +H E R + + SR + + T+S G E+
Sbjct: 1621 --SAREQS---RHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARS 1675
Query: 792 -PGGKRKYKTRH---LEGTNEVAQPSREFASKAKDSHYQKSSSKLDGN---YKNESDTFS 844
PG ++ +RH + + + R+ +S DS + SS + + ESDT S
Sbjct: 1676 SPG--ERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQS 1733
Query: 845 DSRSSDRETKHKRRKRKTRSLSVE-IVYEGKATDTTKHHKKKKKKHKKKHKKHHGDNASR 903
S + + TR S E G H++ + H + G SR
Sbjct: 1734 VSAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSR 1793
Query: 904 SPVVITIDSDSDKDSEVKEDT 924
DS S+ +DT
Sbjct: 1794 HEQ--ARDSSRHSASQEGQDT 1812
Score = 51.6 bits (122), Expect = 4e-06
Identities = 96/440 (21%), Positives = 161/440 (36%), Gaps = 71/440 (16%)
Query: 523 SSGDSDVSRCSSPHSVLGKDEQINKGHCDSSTRIKSKKEEKRSTSLSSPRNLNSSVRGDR 582
S G SD SR S + + + DSS S+ E ST R+ + +V+G
Sbjct: 3145 SQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEA-STHADISRH-SQAVQGQ- 3201
Query: 583 VYSPYNHRHRKRGRSRSSDSRSQSRSGHDQKNHRKHHGKKRMKSKRSRSRESSRPRGRRD 642
S + R R++G S S DS S+ GH + + R S R R
Sbjct: 3202 --SEGSRRSRRQGSSVSQDSDSE---GHSEDSERW---------------SGSASRNHRG 3241
Query: 643 KKRSRTRDSSWSRRSQTLSLSSESTSRSRSRSS-------DHGKRRSRSRNRDRYYLRNN 695
+ ++R S RS + S RSR S G + + S + R
Sbjct: 3242 SVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPGER 3301
Query: 696 YGSRYKWEYTYYSRNKDRDGYESSYRRRTLSRAHYSR---QSSSPEFRVQSFSERTNARK 752
+GSR++ ++ D + R + S SR S S + SE ++ +
Sbjct: 3302 HGSRHQ-------QSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQS 3354
Query: 753 KNNHSERKYYYYERHRS-RSLSSNRSRTASTGTDRV----RNEKPGGKRKYKTRHLEGTN 807
+ H + + S R S RS + + +V ++E G+ + T +G++
Sbjct: 3355 VSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSH 3414
Query: 808 --EVAQPSREFASK----------------AKDSHYQKSSSKLDGNYKNESDTFSDSRSS 849
+ SR AS+ + SHY++S + + + S T S RS
Sbjct: 3415 HEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSD 3474
Query: 850 DRETKHKRRKRKTRSLSVEIVYEGKATDTTKHHKKKKKKHKKKHKKHHGDNASRSPVV-- 907
+ R ++ + E +G + HH+ + +H + G S P
Sbjct: 3475 ASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQ-SGQGQSAGPRTSR 3533
Query: 908 -----ITIDSDSDKDSEVKE 922
++ DSDS SE E
Sbjct: 3534 NQGSSVSQDSDSQGHSEDSE 3553
Score = 50.8 bits (120), Expect = 6e-06
Identities = 81/403 (20%), Positives = 146/403 (36%), Gaps = 47/403 (11%)
Query: 499 SDSEDLGSYEKMETVKTQEQEQSYSSGDSDVSRCSSPHSVLGKDEQINKGHCDSSTRIKS 558
SD++ + ++ + + QE + R S + EQ H + T
Sbjct: 2378 SDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGG 2437
Query: 559 KKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRSQSRSGHDQKNHRKH 618
++ + S R+ S D ++ + GR S + RSGH +H
Sbjct: 2438 RQGSHHKQARDSSRHSTSQEGQDTIHG--HPGSSSGGRQGSHYEQLVDRSGHSGSHH--S 2493
Query: 619 HGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTLSLSSESTSRSRS---RSS 675
H + +S S SR R+ + ++ D S S+ SS + S S +
Sbjct: 2494 HTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQ 2553
Query: 676 DHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRDGYESSYRRRTLSRAHYSRQSS 735
G R SR N+GS +S++ D G+ R + S + S+
Sbjct: 2554 SEGPRTSR-----------NWGSS-------FSQDSDSQGHSEDSERWSGSASRNHHGSA 2595
Query: 736 SPEFRVQSFSERTNARKKNNHSERKYYYYERHRSRSLSSNRSRTASTGTDRVRNEKPGGK 795
+ R S R++ + H + SR + ++T+S G +E+ +
Sbjct: 2596 QEQLRDGSRHPRSHQEDRAGHG------HSADSSRQSGTRHTQTSSGGQAASSHEQ--AR 2647
Query: 796 RKYKTRHLEGTNEVAQPSREFASKAKDSHYQKSSSKLDGNYKNESDTFSDSRSSDRETKH 855
RH + A SR + H Q SS+ D ++ +S S++SD E
Sbjct: 2648 SSAGERHGSHHQQSADSSRH----SGIGHGQASSAVRDSGHRG----YSGSQASDNEGHS 2699
Query: 856 KRRKRKTRSLSVEIVYEGKATDTTKHHKKKKKKHKKKHKKHHG 898
+ T+S+S G+A + H++ + + H G
Sbjct: 2700 E--DSDTQSVSA----HGQAGSHQQSHQESARGRSGETSGHSG 2736
Score = 49.7 bits (117), Expect = 1e-05
Identities = 75/345 (21%), Positives = 119/345 (34%), Gaps = 77/345 (22%)
Query: 589 HRHRKRGRSRSSDSRSQSRSGHDQKNHRKHHGKKRMKSKRSRSRESSRPRGRRDKKRSRT 648
H+HRK +H KH K+ ++K +R R SS R R ++K ++
Sbjct: 99 HKHRKH------------------SHHDKHEDNKQEENKENRKRPSSLER-RNNRKGNKG 139
Query: 649 RDSSWSRRSQTLSLSSESTSRSRSRSSDHGKRRS--RSRNRDRYYLRNNYGSRYKWEYTY 706
R S S T R SS K R +R+ Y +N++ S K
Sbjct: 140 R-----------SKSPRETGGKRHESSSEKKERKGYSPTHREEEYGKNHHNSSKK----- 183
Query: 707 YSRNKDRDGYESSYRRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSERKY----- 761
+NK + R+R R + + ++ T ++ H Y
Sbjct: 184 -EKNKTENTRLGDNRKRLSERLEEKEDNEEGVYDYENTGRMTQKWIQSGHIATYYTIQDE 242
Query: 762 ------------YYYERHRS----RSLSSNRSR---TASTGTDRVRNEKPGGKRKYKTRH 802
YER RS S NRSR T+ R K G R + R
Sbjct: 243 AYDTTDSLLEENKIYERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRD 302
Query: 803 LEGTNEVAQPSREFASKAKDSHYQKSSSKLDGN---YKNESDTFSDSRSSDRETKHKRRK 859
EG +E ++ R S +++ H DG+ ++ D S S+D + R
Sbjct: 303 SEGHSEDSE--RHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRH 360
Query: 860 RKTRSLSVEIVYEGKATDTTKHHKKKKKKHKKKHKKHHGDNASRS 904
+T S T H++ + ++H H +A S
Sbjct: 361 AETSSRG----------QTASSHEQARSSPGERHGSGHQQSADSS 395
Score = 49.3 bits (116), Expect = 2e-05
Identities = 94/429 (21%), Positives = 151/429 (35%), Gaps = 65/429 (15%)
Query: 533 SSPHSVLGKDEQI------NKGHC---DSSTRIKSKKEEKRSTSLSSPRNLNSSVRG--- 580
SS HS G+ + N+G DS ++ S+ E+ S S S RN S +
Sbjct: 3515 SSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSAS--RNHRGSAQEQSR 3572
Query: 581 DRVYSPYNHRHRKRGRSRSSDSRSQS-------------RSGHDQ------KNHRKHHGK 621
D P +H + G S++S QS S H+Q + H HH +
Sbjct: 3573 DGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQ 3632
Query: 622 KRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTLSLSSESTSRSRSRSSDHGKRR 681
S+ S RD S R SS S+ S + S +S ++S S G +
Sbjct: 3633 SADSSRHSGIGHGQASSAVRD---SGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQ 3689
Query: 682 S--RSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRDGYESSYRRRTLSRAHYSRQSSSPEF 739
+ R R R+ + ++ + + +++ G H + SS
Sbjct: 3690 QSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHS 3749
Query: 740 RVQSFSERTNARKKNNHSERKYYYYERHRSRS--LSSNRSRTASTGTD------------ 785
Q + + R+ Y+E+ RS S+ S T S G
Sbjct: 3750 ASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSA 3809
Query: 786 --RVRNEKPGG--KRKYKTRHLEGTNEVAQPSREFASKAKDSHYQKSSSKLDGNYKNESD 841
RNE+ G R +RH E + + A SR S +S + S + + +SD
Sbjct: 3810 SRETRNEEQSGDGSRHSGSRHHEASTQ-ADSSRHSQSGQGESAGSRRSRRQGSSVSQDSD 3868
Query: 842 TFSDSRSSDRETKHKRRKRKTRSLSVEIVYEGKA------TDTTKHHKKKKKKHKKKHKK 895
+ + S+R ++ R S E +G DT H + + K
Sbjct: 3869 SEAYPEDSERRSESASRNH--HGSSREQSRDGSRHPGSSHRDTASHVQSSPVQSDSSTAK 3926
Query: 896 HHGDNASRS 904
HG +S S
Sbjct: 3927 EHGHFSSLS 3935
Score = 48.5 bits (114), Expect = 3e-05
Identities = 79/320 (24%), Positives = 121/320 (37%), Gaps = 52/320 (16%)
Query: 499 SDSEDLGSYEKMETVKTQEQEQSYSSGDSDVSRCSSPHSVLGKDEQINKGHCDSSTRIKS 558
SD++ + ++ + + QE + R S + EQ H +
Sbjct: 3674 SDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGG 3733
Query: 559 KKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRSQSRSGHDQKNHR-- 616
++ + + S R+ S D + + R+ GR S +S RSGH +H
Sbjct: 3734 RQGSRHEQARDSSRHSASQEGQDTIRG--HPGSRRGGRQGSYHEQSVDRSGHSGSHHSHT 3791
Query: 617 -------KHHGK--KRMKSKRSRSRE----SSRPRGRRDKKRSRTRDSSWSRRSQTLSLS 663
HG+ R S+ +R+ E SR G R + S DS SR SQ+
Sbjct: 3792 TSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEASTQADS--SRHSQSGQGE 3849
Query: 664 SESTSRSR------SRSSDHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRDG-- 715
S + RSR S+ SD S R RN++GS SR + RDG
Sbjct: 3850 SAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNHHGS---------SREQSRDGSR 3900
Query: 716 YESSYRRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNH-----SERKYYYYERHRSR 770
+ S R T S SSP VQS S + K++ H + Y+ + R
Sbjct: 3901 HPGSSHRDTASHV-----QSSP---VQSDS---STAKEHGHFSSLSQDSAYHSGIQSRGS 3949
Query: 771 SLSSNRSRTASTGTDRVRNE 790
SS+ S GT+R + +
Sbjct: 3950 PHSSSSYHYQSEGTERQKGQ 3969
Score = 45.1 bits (105), Expect = 4e-04
Identities = 77/404 (19%), Positives = 144/404 (35%), Gaps = 49/404 (12%)
Query: 499 SDSEDLGSYEKMETVKTQEQEQSYSSGDSDVSRCSSPHSVLGKDEQINKGHCDSSTRIKS 558
SD++ + ++ + + + QE + S + EQ H + +
Sbjct: 2702 SDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRG 2761
Query: 559 KKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRG-RSRSSDSRSQSRSGHDQKNHRK 617
++ + + S R+ S D + H RG R S SGH +H
Sbjct: 2762 RQGSRHEQAQDSSRHSASQDGQDTIRG---HPGSSRGGRQGYHHEHSVDSSGHSGSHH-- 2816
Query: 618 HHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDS---SWSRRSQTLSLSSESTSRSRSRS 674
H + +S SR + SR R + ++ D S SR + + + S +
Sbjct: 2817 SHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQG 2876
Query: 675 SDHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRDGYESSYRRRTLSRAHYSRQS 734
G RRSR + + S++ D +G+ R + S + S
Sbjct: 2877 QSEGSRRSRRQG------------------SSVSQDSDSEGHSEDSERWSGSASRNHHGS 2918
Query: 735 SSPEFRVQSFSERTNARKKNNHSERKYYYYERHRSRSLSSNRSRTASTGTDRVRNEKPGG 794
+ + R S R++ + H + SR + ++T+S G +E+
Sbjct: 2919 AQEQLRDGSRHPRSHQEDRAGHG------HSADSSRQSGTRHTQTSSGGQAASSHEQ--A 2970
Query: 795 KRKYKTRHLEGTNEVAQPSREFASKAKDSHYQKSSSKLDGNYKNESDTFSDSRSSDRETK 854
+ RH + A SR + H Q SS+ D ++ +S S++SD E
Sbjct: 2971 RSSAGERHGSHHQQSADSSRH----SGIGHGQASSAVRDSGHRG----YSGSQASDNEGH 3022
Query: 855 HKRRKRKTRSLSVEIVYEGKATDTTKHHKKKKKKHKKKHKKHHG 898
+ T+S+S G+A + H++ + + H G
Sbjct: 3023 SE--DSDTQSVSA----HGQAGSHQQSHQESARGRSGETSGHSG 3060
Score = 44.3 bits (103), Expect = 6e-04
Identities = 87/426 (20%), Positives = 144/426 (33%), Gaps = 40/426 (9%)
Query: 533 SSPHSVLGKDEQINKGHCDSSTRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNH--- 589
SS HS ++G D+S + R+T S G R + H
Sbjct: 2808 SSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADI 2867
Query: 590 -RHRKRGRSRSSDSRSQSRSGHDQKNHRKHHGKKRMKSKRSRSRESSRPRGRRDKKRSRT 648
RH + + +S SR R G G S+ S S R + +
Sbjct: 2868 SRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGH----SEDSERWSGSASRNHHGSAQEQL 2923
Query: 649 RDSSWSRRSQT-------LSLSSESTSRSRSRSSDHGKRRSRSRNRDRYYLRNNYGSRYK 701
RD S RS S S S +R + G + + S + R +GS ++
Sbjct: 2924 RDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQ 2983
Query: 702 WEYTYYSRNKDRDGYESSYRRRTLSRAHYSRQSSSPEFRVQ-SFSERTNARKKNNHSERK 760
+ G SS R + R + Q+S E + S ++ +A + ++
Sbjct: 2984 QSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQS 3043
Query: 761 YYYYERHRSRSLSSNRSRTASTGTDRVRNEKPGGKRKYKTRHLEGT-NEVAQ-PSREFAS 818
+ R RS S + + ++E G TR +G+ +E AQ SR AS
Sbjct: 3044 HQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSAS 3103
Query: 819 K----------------AKDSHYQKSSSKLDGNYKNESDTFSDSRSSDRETKHKRRKRKT 862
+ + H++ S + + S T S RS + R
Sbjct: 3104 QYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASR 3163
Query: 863 RSLSVEIVYEGKATDTTKHHKKKKKKHKKKHK-----KHHGDNAS-RSPVVITIDSDSDK 916
+ + E + ++HH+ +H + G S R ++ DSDS+
Sbjct: 3164 TTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEG 3223
Query: 917 DSEVKE 922
SE E
Sbjct: 3224 HSEDSE 3229
Score = 41.2 bits (95), Expect = 0.005
Identities = 46/229 (20%), Positives = 83/229 (36%), Gaps = 18/229 (7%)
Query: 505 GSYEKMETVKTQEQEQSYSSGDSDVSRCSSPHSVLGKDEQINKGHCDSSTRIKSKKEEKR 564
GSY + ++V S+ S + R + H G +S +++++
Sbjct: 3771 GSYHE-QSVDRSGHSGSHHSHTTSQGRSDASHG--------QSGSRSASRETRNEEQSGD 3821
Query: 565 STSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRSQSRSGHDQKNHRKHHGKKRM 624
+ S R+ +S + D + RH + G+ S+ SR R G
Sbjct: 3822 GSRHSGSRHHEASTQAD------SSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPED 3875
Query: 625 KSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTLSLSSESTSRSRSRSSDHGKRRSRS 684
+RS S + R++ R +R S R + S S + +HG S S
Sbjct: 3876 SERRSESASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLS 3935
Query: 685 RNRDRYYLRNNYGSRY-KWEYTYYSRNKDRDGYESS--YRRRTLSRAHY 730
++ + + GS + Y Y S +R +S +R + A Y
Sbjct: 3936 QDSAYHSGIQSRGSPHSSSSYHYQSEGTERQKGQSGLVWRHGSYGSADY 3984
Score = 32.3 bits (72), Expect = 2.4
Identities = 29/118 (24%), Positives = 53/118 (44%), Gaps = 15/118 (12%)
Query: 742 QSFSERTNARKKN----NHSERKYYYYERHRSRSLSSNRSRTASTGTDRVRNEKPGGKRK 797
Q++ E T RK+N H RK+ ++++H N+ + RN + G K +
Sbjct: 83 QAYYEST--RKENLPISGHKHRKHSHHDKHEDNKQEENKENRKRPSSLERRNNRKGNKGR 140
Query: 798 YKTRHLEG--TNEVAQPSRE---FASKAKDSHYQK---SSSKLDGNYKNESDTFSDSR 847
K+ G +E + +E ++ ++ Y K +SSK + N K E+ D+R
Sbjct: 141 SKSPRETGGKRHESSSEKKERKGYSPTHREEEYGKNHHNSSKKEKN-KTENTRLGDNR 197
>gi|15055543 splicing factor, arginine/serine-rich 2B [Homo sapiens]
Length = 282
Score = 71.2 bits (173), Expect = 5e-12
Identities = 63/203 (31%), Positives = 96/203 (47%), Gaps = 26/203 (12%)
Query: 622 KRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTLSLSSES---TSRSRSRSSDHG 678
+ ++ + +R PR R+ + R R+R + RRS++ S S RSRSR
Sbjct: 83 RELRVQVARYGRRDLPRSRQGEPRGRSRGGGYGRRSRSYGRRSRSPRRRHRSRSRGPSCS 142
Query: 679 KRRSRSRNRDRYYLRNNYG----SRYKWEYTYYSRNKDRD-----------GYESS-YRR 722
+ RSRSR R Y R+ Y SR ++ + YSR++ R+ GY +S Y R
Sbjct: 143 RSRSRSRYRGSRYSRSPYSRSPYSRSRYSRSPYSRSRYRESRYGGSHYSSSGYSNSRYSR 202
Query: 723 RTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSERKYYYYERHRSRSLSSNRSRTAST 782
SR+H S+ SS R S S+ ++AR+ + S R RSRS SS+ +R+
Sbjct: 203 YHSSRSH-SKSGSSTSSRSASTSKSSSARRSKSSS------VSRSRSRSRSSSMTRSPPR 255
Query: 783 GTDRVRNEKPGGKRKYKTRHLEG 805
+ R + KR K+ EG
Sbjct: 256 VSKRKSKSRSRSKRPPKSPEEEG 278
Score = 52.0 bits (123), Expect = 3e-06
Identities = 52/147 (35%), Positives = 68/147 (46%), Gaps = 14/147 (9%)
Query: 554 TRIKSKKEEKRSTSLSSPRNLN-SSVRGDRV-YSPYNHRHRKRGR-SRSSDSRSQSRSGH 610
+R ++ RS S R+ + S RG R SPY+ R R SRS SRS+ R
Sbjct: 125 SRSPRRRHRSRSRGPSCSRSRSRSRYRGSRYSRSPYSRSPYSRSRYSRSPYSRSRYRESR 184
Query: 611 DQKNHRKHHGKKRMKSKRSRSRESSRPRGRRDKKRS-RTRDSSWSRRSQTLSLSSESTSR 669
+H G + R S S G RS T SS +RRS++ SS S SR
Sbjct: 185 YGGSHYSSSGYSNSRYSRYHSSRSHSKSGSSTSSRSASTSKSSSARRSKS---SSVSRSR 241
Query: 670 SRSRSSDH-------GKRRSRSRNRDR 689
SRSRSS KR+S+SR+R +
Sbjct: 242 SRSRSSSMTRSPPRVSKRKSKSRSRSK 268
Score = 50.4 bits (119), Expect = 8e-06
Identities = 53/187 (28%), Positives = 76/187 (40%), Gaps = 15/187 (8%)
Query: 557 KSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRSQSRSGHDQKNHR 616
+S++ E R S S G R SP RHR R R S SRS+SRS
Sbjct: 99 RSRQGEPRGRSRGGGYGRRSRSYGRRSRSP-RRRHRSRSRGPSC-SRSRSRS-------- 148
Query: 617 KHHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTLSLSSESTSRSRSRSSD 676
++ G + +S SRS S R RSR R+S + + S S S S
Sbjct: 149 RYRGSRYSRSPYSRSPYSRSRYSRSPYSRSRYRESRYGGSHYSSSGYSNSRYSRYHSSRS 208
Query: 677 HGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRDGYESS-----YRRRTLSRAHYS 731
H K S + +R +++ R K SR++ R + +R++ SR+
Sbjct: 209 HSKSGSSTSSRSASTSKSSSARRSKSSSVSRSRSRSRSSSMTRSPPRVSKRKSKSRSRSK 268
Query: 732 RQSSSPE 738
R SPE
Sbjct: 269 RPPKSPE 275
Score = 43.1 bits (100), Expect = 0.001
Identities = 61/241 (25%), Positives = 92/241 (38%), Gaps = 44/241 (18%)
Query: 629 SRSRESSRPRGRRDKKRSRTRDSSWSRRSQTLSLSSESTSRSRSRSSDHGKRRSRSRNRD 688
++ E++ D + R + + + RR L S + R RSR +G RRSRS
Sbjct: 68 AQDAEAAMDGAELDGRELRVQVARYGRRD--LPRSRQGEPRGRSRGGGYG-RRSRS---- 120
Query: 689 RYYLRNNYGSRYKWEYTYYSRNKDRDGYESSYRRRTLSRAH---YSRQSSSPEFRVQSFS 745
YG R + S RRR SR+ SR S +R +S
Sbjct: 121 -------YGRRSR-----------------SPRRRHRSRSRGPSCSRSRSRSRYRGSRYS 156
Query: 746 ERTNARKKNNHSERKYYYYERHRSRSLSSNRSRTASTGTDRVRNEKPGGKRKYKTRHLEG 805
+R + S Y R R R S +S+G R + R +
Sbjct: 157 RSPYSRSPYSRSRYSRSPYSRSRYRESRYGGSHYSSSGYSNSRYSRYHSSRSH------- 209
Query: 806 TNEVAQPSREFASKAKDSHYQKSSSKLDGNYKNESDTFSDSRSSDRETKHKRRKRKTRSL 865
+ + S AS +K S ++S S ++ S + S +RS R +K RK K+RS
Sbjct: 210 SKSGSSTSSRSASTSKSSSARRSKSSSVSRSRSRSRSSSMTRSPPRVSK---RKSKSRSR 266
Query: 866 S 866
S
Sbjct: 267 S 267
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 70.5 bits (171), Expect = 8e-12
Identities = 76/373 (20%), Positives = 143/373 (38%), Gaps = 45/373 (12%)
Query: 600 SDSRSQSRSGHDQKNHRKHHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQT 659
S R + ++K ++ ++ K +R R RE R R RR+++R R R+ + +
Sbjct: 282 SKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKER 341
Query: 660 LSLSSESTSRSRSRSSDHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRDGYESS 719
R R++ D R R R RDR R R K +++DR+
Sbjct: 342 ERERERDRDRDRTKERD----RDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERER 397
Query: 720 YRRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSERKYYYYERHRSRSLSSNRSRT 779
R R R + E + ER +K++ + + Y R R L R +
Sbjct: 398 EREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKL---REKE 454
Query: 780 ASTGTDRVRNEKPGGKRKYKTRHLEGTNEVAQPSREFASKAK--------------DSHY 825
A+ +R++N + ++K + E E + RE A +AK D Y
Sbjct: 455 AAY-QERLKNWEIRERKKTREYEKEAERE-EERRREMAKEAKRLKEFLEDYDDDRDDPKY 512
Query: 826 QKSSSKLDGNYKNESDTFSDSRSSDRETKHKRRKRKTRSLSVEIVYEGKATDTTKHHKKK 885
+ S+ E + +D R KR K + + ++ EG + + +
Sbjct: 513 YRGSALQKRLRDREKEMEADERD------RKREKEELEEIRQRLLAEGHPDPDAELQRME 566
Query: 886 KKKHKKKHKKHHGDNASRSPVVITIDSDSDKDSEVKEDTECDNSGP----QDPLQNEFLA 941
++ +++ + I + +S+++ E K++ E P ++P Q L
Sbjct: 567 QEAERRRQPQ------------IKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPCLK 614
Query: 942 PSLEPFETKDVVT 954
P+L P + V+
Sbjct: 615 PTLRPISSAPSVS 627
Score = 49.7 bits (117), Expect = 1e-05
Identities = 76/364 (20%), Positives = 132/364 (36%), Gaps = 43/364 (11%)
Query: 495 VELSSDSEDLGSYEKM---ETVKTQEQEQSYSSGDSDVSRCSSPHSVLGKDEQINKGHCD 551
+E+ D DL S E +T K E+E+ + ++ + + +
Sbjct: 267 IEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERE 326
Query: 552 SSTRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSD---SRSQSRS 608
+ ++E+++ R+ + +R R R R R RSSD RS+SR
Sbjct: 327 REREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSRE 386
Query: 609 -GHDQKNHRKHHGKKRMKSKRSRSRESSRPRGR-------RDKKRSRTRD--SSWSRRSQ 658
D++ R+ ++ + +R R RE R R R +DKKR R D ++ RR
Sbjct: 387 KSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKL 446
Query: 659 TLSLSSESTS----------RSRSRSSDHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYS 708
L + + R R ++ ++ K R R R + R K Y
Sbjct: 447 ERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKE--AKRLKEFLEDYD 504
Query: 709 RNKDRDGYESSYRRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSE-RKYYYYERH 767
++D Y YR L + R+ + ER R+K E R+ E H
Sbjct: 505 DDRDDPKY---YRGSALQKRLRDRE------KEMEADERDRKREKEELEEIRQRLLAEGH 555
Query: 768 RSRSLSSNRSRTASTGTDRVRNEKPGGKRKYKTRHLEGTNEVAQPSREFASKAKDSHYQK 827
R + R +P K++ ++ E + + RE + ++ QK
Sbjct: 556 PDPDAELQRME-----QEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQK 610
Query: 828 SSSK 831
K
Sbjct: 611 PCLK 614
Score = 32.7 bits (73), Expect = 1.8
Identities = 23/81 (28%), Positives = 39/81 (48%), Gaps = 9/81 (11%)
Query: 818 SKAKDSHYQKSSSKLDGNYKNESDTFSDSRSSDRETKHKRRKRK------TRSLSVEIVY 871
+KA+ ++ +GN + E+ T D + D ETK + + K R S E+
Sbjct: 165 TKAQLDEWKAKKKASNGNARPETVTNDDEEALDEETKRRDQMIKGAIEVLIREYSSELNA 224
Query: 872 EGKATDTTKHHKKKKKKHKKK 892
+ +D+ H +KKKK KK+
Sbjct: 225 PSQESDS---HPRKKKKEKKE 242
Score = 30.8 bits (68), Expect = 7.0
Identities = 24/117 (20%), Positives = 45/117 (38%), Gaps = 12/117 (10%)
Query: 813 SREFASKAKDSHYQKSSSKLDGNYKNESDTFSDSRSSDRETKHKRRKRKTRSLSVEIVYE 872
SRE SK +D+H + K G + E R + + R+R+ R
Sbjct: 278 SREI-SKFRDTHKKLEEEK--GKKEKERQEIEKERRERERERERERERRERE-------- 326
Query: 873 GKATDTTKHHKKKKKKHKKKHKKHHGDNASRSPVVITIDSDSDKDSEVKEDTECDNS 929
+ + + +K+K++ +++ + D + D D+D E D D S
Sbjct: 327 -REREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRS 382
>gi|4827046 U2 small nuclear RNA auxiliary factor 1-like 2 [Homo
sapiens]
Length = 482
Score = 69.7 bits (169), Expect = 1e-11
Identities = 51/134 (38%), Positives = 71/134 (52%), Gaps = 7/134 (5%)
Query: 561 EEKRSTSLSSPRNLNS----SVRGDRVYSPYNHRHRKRGRSRSSDSRSQSRSGHDQKNHR 616
E R LS R +S S R +R+ ++ R RGR S S R+G ++
Sbjct: 341 EANRDIYLSPDRTGSSFGKNSERRERMGHHDDYYSRLRGRRNPSPDHSYKRNGESERKSS 400
Query: 617 KHHGKKRMK-SKRSRSRESSRPRGR-RDKKRSRTRDSSWSRRSQTLS-LSSESTSRSRSR 673
+H GKK K + +SR R +SR RGR RD+ R R+R RS++ S S S S+S SR
Sbjct: 401 RHRGKKSHKRTSKSRERHNSRSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQSSSR 460
Query: 674 SSDHGKRRSRSRNR 687
S G+RRS +R+R
Sbjct: 461 SRSRGRRRSGNRDR 474
Score = 45.8 bits (107), Expect = 2e-04
Identities = 40/98 (40%), Positives = 51/98 (52%), Gaps = 23/98 (23%)
Query: 553 STRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRSQSRSGHDQ 612
S+R + KK KR TS S R+ NS RG +R R R RSR SRS+SRS
Sbjct: 399 SSRHRGKKSHKR-TSKSRERH-NSRSRG-------RNRDRSRDRSRGRGSRSRSRS---- 445
Query: 613 KNHRKHHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRD 650
+ +S+RSRS+ SSR R R ++RS RD
Sbjct: 446 ---------RSRRSRRSRSQSSSRSRS-RGRRRSGNRD 473
Score = 42.7 bits (99), Expect = 0.002
Identities = 41/151 (27%), Positives = 68/151 (45%), Gaps = 12/151 (7%)
Query: 647 RTRDSSWSRRSQTLSLSSESTSRSRSRSSDHGKRRSRSRNRDRYYLRNNYGSRYKWEYTY 706
R ++ + ++ + LS + T S ++S+ RR R + D YY R G R
Sbjct: 333 RNPNNEFWEANRDIYLSPDRTGSSFGKNSE---RRERMGHHDDYYSRLR-GRRNPSPDHS 388
Query: 707 YSRNKDRDGYESSYR-RRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSERKYYYYE 765
Y RN + + S +R +++ R SR+ + R ++ +R+ R + S
Sbjct: 389 YKRNGESERKSSRHRGKKSHKRTSKSRERHNSRSRGRN-RDRSRDRSRGRGSR------S 441
Query: 766 RHRSRSLSSNRSRTASTGTDRVRNEKPGGKR 796
R RSRS S RSR+ S+ R R + G R
Sbjct: 442 RSRSRSRRSRRSRSQSSSRSRSRGRRRSGNR 472
Score = 37.4 bits (85), Expect = 0.074
Identities = 36/137 (26%), Positives = 57/137 (41%), Gaps = 14/137 (10%)
Query: 686 NRDRYYLRNNYGSRYKWEYTYYSRNKDRDGYESSYRRRTLSRAHYSRQSSSPEFRVQSFS 745
NRD Y + GS + S ++R G+ Y R R + S S ++ S
Sbjct: 343 NRDIYLSPDRTGSSFGKN----SERRERMGHHDDYYSRLRGRRNPSPDHS---YKRNGES 395
Query: 746 ERTNARKKNNHS-ERKYYYYERHRSRSLSSNRSRTASTGTDRVRNEKPGGKRKYKTRHLE 804
ER ++R + S +R ERH SRS NR R+ R R+ G + + ++R
Sbjct: 396 ERKSSRHRGKKSHKRTSKSRERHNSRSRGRNRDRS------RDRSRGRGSRSRSRSRSRR 449
Query: 805 GTNEVAQPSREFASKAK 821
+Q S S+ +
Sbjct: 450 SRRSRSQSSSRSRSRGR 466
Score = 30.4 bits (67), Expect = 9.1
Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 1/91 (1%)
Query: 540 GKDEQINKGHCDSSTRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRS 599
G+ E+ + H + ++ K +R S S RN + S R + + RSR
Sbjct: 393 GESERKSSRHRGKKSHKRTSKSRERHNSRSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRR 452
Query: 600 SDSRSQSRSGHDQKNHRKHHGKKRMKSKRSR 630
S S+S SRS + R + + ++S +S+
Sbjct: 453 SRSQSSSRS-RSRGRRRSGNRDRTVQSPKSK 482
>gi|38488727 arginine/serine-rich coiled-coil 1 [Homo sapiens]
Length = 334
Score = 69.7 bits (169), Expect = 1e-11
Identities = 77/253 (30%), Positives = 109/253 (43%), Gaps = 47/253 (18%)
Query: 598 RSSDSRSQSRSGHDQKNHRKHHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRS 657
RSSD+ +SRS +K H ++ S S SR SR +G R +SR++ SWSR
Sbjct: 4 RSSDTEEESRS-----KRKKKHRRRSSSSSSSDSRTYSRKKGGR---KSRSKSRSWSRDL 55
Query: 658 QTLSLSSESTSRSR-SRSSDHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRDGY 716
Q S S + R R S SS +G RR RSR+R R G
Sbjct: 56 QPRSHSYDRRRRHRSSSSSSYGSRRKRSRSRSR-------------------------GR 90
Query: 717 ESSYR-RRTLSRAHYSRQSSSPEFRVQS-FSERTNARKKNNHSERKYYYYERHRSRSLSS 774
SYR +R+ S++ R S P R S SER++ R+ + S + ER + R
Sbjct: 91 GKSYRVQRSRSKSRTRRSRSRPRLRSHSRSSERSSHRRTRSRSRDR----ERRKGRD-KE 145
Query: 775 NRSRTASTGTDR-VRNEKPG--GKRKYKTRHL---EGTNEVAQPSREFASKAKDSHYQKS 828
R + G D+ + N K G G K HL E Q E A+KA ++ K
Sbjct: 146 KREKEKDKGKDKELHNIKRGESGNIKAGLEHLPPAEQAKARLQLVLEAAAKADEALKAKE 205
Query: 829 SSKLDGNYKNESD 841
++ + + E D
Sbjct: 206 RNEEEAKRRKEED 218
Score = 63.5 bits (153), Expect = 1e-09
Identities = 48/145 (33%), Positives = 72/145 (49%), Gaps = 15/145 (10%)
Query: 551 DSSTRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRSQSRS-G 609
+ +R K KK+ +R +S SS + R YS + R +SRS Q RS
Sbjct: 9 EEESRSKRKKKHRRRSSSSSSSD-------SRTYSRKKGGRKSRSKSRSWSRDLQPRSHS 61
Query: 610 HDQKNHRKHHGKKRMKSKRSRSRESSRPRGR-----RDKKRSRTRDSSWSRRSQTLSLSS 664
+D++ + S+R RSR SR RG+ R + +SRTR S R ++ S SS
Sbjct: 62 YDRRRRHRSSSSSSYGSRRKRSRSRSRGRGKSYRVQRSRSKSRTRRSRSRPRLRSHSRSS 121
Query: 665 ESTS--RSRSRSSDHGKRRSRSRNR 687
E +S R+RSRS D +R+ R + +
Sbjct: 122 ERSSHRRTRSRSRDRERRKGRDKEK 146
Score = 53.1 bits (126), Expect = 1e-06
Identities = 64/263 (24%), Positives = 108/263 (41%), Gaps = 29/263 (11%)
Query: 643 KKRSRTRDSSWSRRSQTLSLSSESTSRSRSRSSDHGKRRSRSRNRDRYYLRNNYGSRYKW 702
++ S T + S S+R + S S+S S SR+ K +SR++ R + R+
Sbjct: 3 RRSSDTEEESRSKRKKKHRRRSSSSSSSDSRTYSRKKGGRKSRSKSRSWSRD----LQPR 58
Query: 703 EYTYYSRNKDRDGYESSY---RRRTLSRAH-----YSRQSSSPEFRVQSFSERTNARKKN 754
++Y R + R SSY R+R+ SR+ Y Q S + R + R R +
Sbjct: 59 SHSYDRRRRHRSSSSSSYGSRRKRSRSRSRGRGKSYRVQRSRSKSRTRRSRSRPRLRSHS 118
Query: 755 NHSERKYYYYERHRSRSLSSNRSRTASTGTDRVRNEKPGGKRKYKTRH---------LEG 805
SER + R RSRS R R G D+ + EK K K K H ++
Sbjct: 119 RSSERS--SHRRTRSRS----RDRERRKGRDKEKREKEKDKGKDKELHNIKRGESGNIKA 172
Query: 806 TNEVAQPSREFASKAKDSHYQKSSSKLDGNYKNESDTFSDSRSSDRETKHKRRKRKTRSL 865
E P+ + +KA+ ++++K D K + +++ E + ++ R
Sbjct: 173 GLEHLPPAEQ--AKARLQLVLEAAAKADEALKAKERNEEEAKRRKEEDQATLVEQVKRVK 230
Query: 866 SVEIVYEGKATDTTKHHKKKKKK 888
+E + T K+ KK
Sbjct: 231 EIEAIESDSFVQQTFRSSKEVKK 253
Score = 45.4 bits (106), Expect = 3e-04
Identities = 46/158 (29%), Positives = 66/158 (41%), Gaps = 15/158 (9%)
Query: 498 SSDSEDLGSYEKMETVKTQEQEQSYSSGDSDVSRCSSPHSVLGKDEQINKGHCDSSTRIK 557
SSD+E+ E K + + +S SS SD S + D R
Sbjct: 5 SSDTEE----ESRSKRKKKHRRRSSSSSSSDSRTYSRKKGGRKSRSKSRSWSRDLQPRSH 60
Query: 558 SKKEEKR-----STSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRSQSRSGHDQ 612
S +R S+S S R + S R S R R + R+R S SR + RS H +
Sbjct: 61 SYDRRRRHRSSSSSSYGSRRKRSRSRSRGRGKSYRVQRSRSKSRTRRSRSRPRLRS-HSR 119
Query: 613 KNHRKHHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRD 650
+ R H + RSRSR+ R +GR +KR + +D
Sbjct: 120 SSERSSH-----RRTRSRSRDRERRKGRDKEKREKEKD 152
Score = 32.0 bits (71), Expect = 3.1
Identities = 41/182 (22%), Positives = 68/182 (37%), Gaps = 20/182 (10%)
Query: 501 SEDLGSYEKMETVKTQEQEQSYSSGDSDVSRCSSPHSVLGKDEQINKGHCDSSTRIKSKK 560
S DL + + + S SS S R S GK ++ + S TR +
Sbjct: 52 SRDLQPRSHSYDRRRRHRSSSSSSYGSRRKRSRSRSRGRGKSYRVQRSRSKSRTRRSRSR 111
Query: 561 EEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRSQSRSGHDQKNHRKHHG 620
RS S SS R+ +HR R RSRS D + R G D++ K
Sbjct: 112 PRLRSHSRSSERS--------------SHR---RTRSRSRDR--ERRKGRDKEKREKEKD 152
Query: 621 KKRMKSKRSRSR-ESSRPRGRRDKKRSRTRDSSWSRRSQTLSLSSESTSRSRSRSSDHGK 679
K + K + R ES + + + + + + ++ +++ R+ + K
Sbjct: 153 KGKDKELHNIKRGESGNIKAGLEHLPPAEQAKARLQLVLEAAAKADEALKAKERNEEEAK 212
Query: 680 RR 681
RR
Sbjct: 213 RR 214
Score = 31.6 bits (70), Expect = 4.1
Identities = 22/90 (24%), Positives = 39/90 (43%), Gaps = 17/90 (18%)
Query: 815 EFASKAKDSHYQKSSSKLDGNYKNESDTFSDSRSSDRETKHKRRKRKTRSLSVEIVYEGK 874
E SK K H ++SSS + SDSR+ R+ ++ + K+RS S ++
Sbjct: 11 ESRSKRKKKHRRRSSSS----------SSSDSRTYSRKKGGRKSRSKSRSWSRDL----- 55
Query: 875 ATDTTKHHKKKKKKHKKKHKKHHGDNASRS 904
H ++++H+ +G RS
Sbjct: 56 --QPRSHSYDRRRRHRSSSSSSYGSRRKRS 83
>gi|50962882 G patch domain containing 8 [Homo sapiens]
Length = 1502
Score = 69.7 bits (169), Expect = 1e-11
Identities = 101/460 (21%), Positives = 186/460 (40%), Gaps = 46/460 (10%)
Query: 502 EDLGSYEK--METVKTQEQEQSYSSGDSDVSRCSSPHSVLGKDEQINKGHCDSSTRIKSK 559
+D+GS K ++ + E +S G + R S G+ + G S
Sbjct: 593 KDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSG-----GRMDAPASGSACSGLN---- 643
Query: 560 KEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRSQSRSGHDQKNHRKHH 619
K+E + S + S+ + S +HRH+K+ + + S K+ RKH
Sbjct: 644 KQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKS-----------SKHKRKHK 692
Query: 620 GKKRMKSKRSRSRESSRPRGRRDKKRSRT---RDSSWSRRSQTLSLSSESTSRSRSRSSD 676
KS ++ S E S+ R +R +K++++ DS + + S + R R R+ D
Sbjct: 693 ADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQD 752
Query: 677 HGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRDGYESSYRR----RTLSRAHYSR 732
+RRS ++ G + ++K S RR R+ +H S+
Sbjct: 753 DSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQ 812
Query: 733 QSSSPEFRVQSFSERTNARKKNNHSERKY-----YYYERHRSRS---LSSNRS--RTAST 782
SS E + S R + + + +SE + + R RSRS SS+RS R+ S+
Sbjct: 813 PSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSS 872
Query: 783 GTDRVRNEK-PGGKRKYKTRHLEGTNEVAQPSREFASKAKDSHYQKSSSKLDGNYKNESD 841
+D ++ +R Y ++ ++ + + + DS Y S + + + SD
Sbjct: 873 SSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSD 932
Query: 842 ---TFSDSRSSDRETKHKRRKRKTRSLSVEIVYEGKATDTTKHHKKKKKKHKKKHKKHHG 898
+ S S+S R H R + ++R S + +K + H + + +
Sbjct: 933 DDYSLSCSQSRSRSRSHTRERSRSRGRSRS---SSCSRSRSKRRSRSTTAHSWQRSRSYS 989
Query: 899 DNASRSPVVITIDSDSDKDSEVKEDTECDNSGPQDPLQNE 938
+ SRS + S S K S E E +SG +D ++++
Sbjct: 990 RDRSRSTRSPSQRSGSRKRSWGHESPEERHSGRRDFIRSK 1029
Score = 64.3 bits (155), Expect = 6e-10
Identities = 97/380 (25%), Positives = 152/380 (40%), Gaps = 41/380 (10%)
Query: 496 ELSSDSEDLGSYEKMETVKTQEQEQSYSSGDSDVSRCSSPH----SVLGKDEQINKGHCD 551
E SS +E S EK + K ++++++ SS +D R P + + D
Sbjct: 697 EKSSKAE---SGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDD 753
Query: 552 SSTRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYS---PYNHRHRKRGRSRSSDS--RSQS 606
S R +E +S G R + P + R+ G RSS S RSQ
Sbjct: 754 SQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQP 813
Query: 607 RSGH----DQKNHRKHHGKKRMKSKRSRSRES----SRPRGRRDKKRSRTRDSSWSRRSQ 658
SG D +HR H S+ +S SR R R ++ S R S S S
Sbjct: 814 SSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSS 873
Query: 659 TLSLSSEST-SRSRSRS----SDHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDR 713
+ + S +S SR RS S SD+ R R R ++Y S + + D
Sbjct: 874 SDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDD 933
Query: 714 DGYESSYRRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSERKYYYYERHRSRSLS 773
D S + R+ SR+H +S S S R+ +++++ R + RSRS S
Sbjct: 934 DYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRS----RSTTAHSWQRSRSYS 989
Query: 774 SNRSRTASTGTDRVRNEKPGGKRKYKTRHLEGTNEVAQPSREFAS----KAKDSHYQKSS 829
+RSR+ + + R G RK H E E R+F +++ HY + S
Sbjct: 990 RDRSRSTRSPSQR------SGSRKRSWGH-ESPEERHSGRRDFIRSKIYRSQSPHYFR-S 1041
Query: 830 SKLDGNYKNESDTFSDSRSS 849
+ +G K + DS+++
Sbjct: 1042 GRGEGPGKKDDGRGDDSKAT 1061
>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 68.9 bits (167), Expect = 2e-11
Identities = 82/349 (23%), Positives = 141/349 (40%), Gaps = 32/349 (9%)
Query: 489 ERTPELVELSSDSEDLGSYEKMETVKTQEQEQSYSSGDSDVSRCSSPHSVLGKDE-QINK 547
+RTP E +S E +++ E S S S SR SS S + +
Sbjct: 483 KRTPN--ETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSS 540
Query: 548 GHCDSSTRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRSQSR 607
G +S+R S K +KR + SP + + R YS R R + D R +R
Sbjct: 541 GSSRTSSRSSSPKRKKRHSRSRSP-TIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNR 599
Query: 608 SGHDQKNHRKHHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTLSLSSES- 666
+ +++ R + + RSRSR+ R R + R R + Q +LS S
Sbjct: 600 NSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKID-----DQRGNLSGNSH 654
Query: 667 TSRSRSRSSDHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRD----GYESSYRR 722
+ ++ + K RSRS ++DR ++ R + + + +++D + +R
Sbjct: 655 KHKGEAKEQERKKERSRSIDKDR-KKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKR 713
Query: 723 RTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSERKYYYYERHRSRSLSSNRSRTAST 782
+ S +SR S S ++ R +++K +K+ S S SS RS + S
Sbjct: 714 KRESERTFSR-SGSISVKIIRHDSRQDSKKSTTKDSKKH-------SGSDSSGRSSSESP 765
Query: 783 GTDRVRNEKPGGKRKYKTRHLEGTNEVAQPSREFASKAKDSHYQKSSSK 831
G+ + + K K +H + + S+ KA H KS S+
Sbjct: 766 GSSKEKKAK-------KPKH--SRSRSVEKSQRSGKKASRKHKSKSRSR 805
Score = 68.2 bits (165), Expect = 4e-11
Identities = 108/415 (26%), Positives = 157/415 (37%), Gaps = 71/415 (17%)
Query: 522 YSSGDSDVSRCSSPHSVLGKDEQINKGHCDSSTRIKSKKE-----EKRSTSLSSPRNLNS 576
Y SGDS+ R D++ + RI+ K+E EK L +
Sbjct: 391 YGSGDSEDERSDRGSESSDTDDE------ELRHRIRQKQEAFWRKEKEQQLLHDKQMEEE 444
Query: 577 SVRGDRVYSPYNHRHRKRGRS------RSSDS---RSQSRSGHDQKNHRKHHGKKRMKSK 627
+ +RV N K S R +D + R+ ++ + + + + K K
Sbjct: 445 KQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEK 504
Query: 628 RSRSRESSRPRG------RRDKKRSRTRDSSWSRRSQTLSLSSESTS------RSRSRSS 675
+ RSR S G R S SS+S S + SS S+S SRSRS
Sbjct: 505 QGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSP 564
Query: 676 DHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRDGYESSYRRRTLSRAHYSRQSS 735
RRSRSR +Y R K E + +R K RD S+ R ++ R +S
Sbjct: 565 TIKARRSRSR---------SYSRRIKIE-SNRARVKIRDRRRSN--RNSIERERRRNRSP 612
Query: 736 SPEFRVQSFSERTNARKKNNHSERKYYYYERHRSRSLSSNRSRTASTGTDRVRNEKPGGK 795
S E R R+ +R ++ + R SRS S +R + D R G
Sbjct: 613 SRERR------RSRSRSRDRRTNR--------ASRSRSRDRRK-----IDDQRGNLSGNS 653
Query: 796 RKYKTRHLEGTNEVAQP-SREFASKAKDSHYQKSSSKLDGNYKNESDTFSDSRSSDRETK 854
K+K E + + S + K KD ++ K K E F S DR K
Sbjct: 654 HKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDR-LK 712
Query: 855 HKRRKRKT----RSLSVEIVYEGKATDTTKHHKKKKKKHKKKHKKHHGDNASRSP 905
KR +T S+SV+I+ D+ K K KKH G ++S SP
Sbjct: 713 RKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSS--GRSSSESP 765
>gi|154146193 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 68.9 bits (167), Expect = 2e-11
Identities = 82/349 (23%), Positives = 141/349 (40%), Gaps = 32/349 (9%)
Query: 489 ERTPELVELSSDSEDLGSYEKMETVKTQEQEQSYSSGDSDVSRCSSPHSVLGKDE-QINK 547
+RTP E +S E +++ E S S S SR SS S + +
Sbjct: 483 KRTPN--ETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSS 540
Query: 548 GHCDSSTRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRSQSR 607
G +S+R S K +KR + SP + + R YS R R + D R +R
Sbjct: 541 GSSRTSSRSSSPKRKKRHSRSRSP-TIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNR 599
Query: 608 SGHDQKNHRKHHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTLSLSSES- 666
+ +++ R + + RSRSR+ R R + R R + Q +LS S
Sbjct: 600 NSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKID-----DQRGNLSGNSH 654
Query: 667 TSRSRSRSSDHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRD----GYESSYRR 722
+ ++ + K RSRS ++DR ++ R + + + +++D + +R
Sbjct: 655 KHKGEAKEQERKKERSRSIDKDR-KKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKR 713
Query: 723 RTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSERKYYYYERHRSRSLSSNRSRTAST 782
+ S +SR S S ++ R +++K +K+ S S SS RS + S
Sbjct: 714 KRESERTFSR-SGSISVKIIRHDSRQDSKKSTTKDSKKH-------SGSDSSGRSSSESP 765
Query: 783 GTDRVRNEKPGGKRKYKTRHLEGTNEVAQPSREFASKAKDSHYQKSSSK 831
G+ + + K K +H + + S+ KA H KS S+
Sbjct: 766 GSSKEKKAK-------KPKH--SRSRSVEKSQRSGKKASRKHKSKSRSR 805
Score = 68.2 bits (165), Expect = 4e-11
Identities = 108/415 (26%), Positives = 157/415 (37%), Gaps = 71/415 (17%)
Query: 522 YSSGDSDVSRCSSPHSVLGKDEQINKGHCDSSTRIKSKKE-----EKRSTSLSSPRNLNS 576
Y SGDS+ R D++ + RI+ K+E EK L +
Sbjct: 391 YGSGDSEDERSDRGSESSDTDDE------ELRHRIRQKQEAFWRKEKEQQLLHDKQMEEE 444
Query: 577 SVRGDRVYSPYNHRHRKRGRS------RSSDS---RSQSRSGHDQKNHRKHHGKKRMKSK 627
+ +RV N K S R +D + R+ ++ + + + + K K
Sbjct: 445 KQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEK 504
Query: 628 RSRSRESSRPRG------RRDKKRSRTRDSSWSRRSQTLSLSSESTS------RSRSRSS 675
+ RSR S G R S SS+S S + SS S+S SRSRS
Sbjct: 505 QGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSP 564
Query: 676 DHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRDGYESSYRRRTLSRAHYSRQSS 735
RRSRSR +Y R K E + +R K RD S+ R ++ R +S
Sbjct: 565 TIKARRSRSR---------SYSRRIKIE-SNRARVKIRDRRRSN--RNSIERERRRNRSP 612
Query: 736 SPEFRVQSFSERTNARKKNNHSERKYYYYERHRSRSLSSNRSRTASTGTDRVRNEKPGGK 795
S E R R+ +R ++ + R SRS S +R + D R G
Sbjct: 613 SRERR------RSRSRSRDRRTNR--------ASRSRSRDRRK-----IDDQRGNLSGNS 653
Query: 796 RKYKTRHLEGTNEVAQP-SREFASKAKDSHYQKSSSKLDGNYKNESDTFSDSRSSDRETK 854
K+K E + + S + K KD ++ K K E F S DR K
Sbjct: 654 HKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDR-LK 712
Query: 855 HKRRKRKT----RSLSVEIVYEGKATDTTKHHKKKKKKHKKKHKKHHGDNASRSP 905
KR +T S+SV+I+ D+ K K KKH G ++S SP
Sbjct: 713 RKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSS--GRSSSESP 765
>gi|9945320 cyclin L1 [Homo sapiens]
Length = 526
Score = 67.4 bits (163), Expect = 7e-11
Identities = 56/189 (29%), Positives = 85/189 (44%), Gaps = 22/189 (11%)
Query: 525 GDSDVSRCSSPHSVLGKDEQ--------INKGHCDSSTRIKS-----KKEEKRSTSLSSP 571
G S S+ SSP V +++ + K D KS +K+ KRS + S
Sbjct: 333 GFSPASKPSSPREVKAEEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSA 392
Query: 572 RNLNSSVRG-DRVYSPYNHRHRKRGRSR--SSDSRSQSRSGHDQKNHRKHHGKKRMKSKR 628
S R R ++P H + +R RS SS SRS+SRS + +HG +K+K
Sbjct: 393 SRSRSRTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRSRSHSESPRRHHNHGSPHLKAKH 452
Query: 629 SRSRESSRPRGRRDKKRSRTRDSSWSRRSQTLSLSSESTSRSRSRSSDHGKRRSRSRNRD 688
+R S R +K+SR+R S SR S++ + R H RR RSR+ +
Sbjct: 453 TRDDLKSSNRHGHKRKKSRSRSQSKSRD------HSDAAKKHRHERGHHRDRRERSRSFE 506
Query: 689 RYYLRNNYG 697
R + ++G
Sbjct: 507 RSHKSKHHG 515
Score = 43.5 bits (101), Expect = 0.001
Identities = 48/198 (24%), Positives = 70/198 (35%), Gaps = 12/198 (6%)
Query: 485 KPLAERTPELVELSSDSEDLGSYEKMETVKTQEQEQSYSSGDSDVSRCSSPHSVLGKDEQ 544
KP + R + E S S ++ + +K + Q + Y+ D R + S +
Sbjct: 339 KPSSPREVKAEEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSR 398
Query: 545 INKGHCDSSTRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRS 604
+ R RS + SS S R +S RH G
Sbjct: 399 TRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRS-----RSHSESPRRHHNHG-----SPHL 448
Query: 605 QSRSGHDQKNHRKHHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTLSLSS 664
+++ D HG KR KS RSRS+ SR KK R RR ++ S
Sbjct: 449 KAKHTRDDLKSSNRHGHKRKKS-RSRSQSKSRDHSDAAKKHRHERGHHRDRRERSRSFER 507
Query: 665 ESTSRSRSRS-SDHGKRR 681
S+ S S HG+ R
Sbjct: 508 SHKSKHHGGSRSGHGRHR 525
Score = 43.1 bits (100), Expect = 0.001
Identities = 49/179 (27%), Positives = 74/179 (41%), Gaps = 37/179 (20%)
Query: 737 PEFRVQSFSERTNARKKNNHSERKYYYYERHRSRSLSSNRSRTASTGTDRVRNEKPGGKR 796
PE R Q+ N +K++ R R RSR+ S +RS T +R
Sbjct: 365 PEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTP--------------RR 410
Query: 797 KYKTRH-LEGTNEVAQPSREFA-SKAKDSHYQKSSSKLDGNYKNESDTFSDSRSSDRETK 854
Y R GT SR + S++ H+ S L + T D +SS+R
Sbjct: 411 HYNNRRSRSGTYSSRSRSRSRSHSESPRRHHNHGSPHLKAKH-----TRDDLKSSNRH-G 464
Query: 855 HKRRKRKTRSLSVEIVYEGKATDTTKHHKKKKKKHK----------KKHK-KHHGDNAS 902
HKR+K ++RS S + +D K H+ ++ H+ + HK KHHG + S
Sbjct: 465 HKRKKSRSRSQSKSRDH----SDAAKKHRHERGHHRDRRERSRSFERSHKSKHHGGSRS 519
Score = 39.7 bits (91), Expect = 0.015
Identities = 46/175 (26%), Positives = 73/175 (41%), Gaps = 30/175 (17%)
Query: 722 RRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSERKYYYYERHRSRSLSSNRSRTAS 781
R+ R+ SR +S R +S + +H+ R++Y R RS + SS RSR+ S
Sbjct: 380 RKDSKRSRNSRSASRSRSRTRS--------RSRSHTPRRHYNNRRSRSGTYSS-RSRSRS 430
Query: 782 TGTDRVRNEKPGGKRKYKTRHLEG--TNEVAQPSREFASKAKDSHYQKSSSKLDGNYKNE 839
R +E P + + HL+ T + + S K K KS S+ ++
Sbjct: 431 ----RSHSESPRRHHNHGSPHLKAKHTRDDLKSSNRHGHKRK-----KSRSRSQSKSRDH 481
Query: 840 SDTFSDSRSSDRETKHKRRKRKTRSLSVEIVYEGKATDTTKHHKKKKKKHKKKHK 894
SD R E H R +R+ RS S E + +KHH + H + +
Sbjct: 482 SDAAKKHR---HERGHHRDRRE-RSRSFE------RSHKSKHHGGSRSGHGRHRR 526
>gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens]
Length = 344
Score = 66.2 bits (160), Expect = 1e-10
Identities = 47/148 (31%), Positives = 70/148 (47%), Gaps = 12/148 (8%)
Query: 552 SSTRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRSQSRSGHD 611
S +R +S+ +RS S S R+++ S R S R R +GR S S+S+ +S
Sbjct: 198 SRSRRRSRSRSRRS-SRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRG 256
Query: 612 QKNHRKHHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTLSL--------- 662
+H + K + RSRSR S + +S++R S SR + L +
Sbjct: 257 SHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVS 316
Query: 663 --SSESTSRSRSRSSDHGKRRSRSRNRD 688
+TSRSRSRS + RSRS +RD
Sbjct: 317 PPPKRATSRSRSRSRSKSRSRSRSSSRD 344
Score = 65.1 bits (157), Expect = 3e-10
Identities = 62/211 (29%), Positives = 99/211 (46%), Gaps = 16/211 (7%)
Query: 587 YNHRHRKRGRSRSSDSRSQS--RSGHDQKNHRKHHGKK-RMKSKRSRSRESSRPRGRRDK 643
Y H++R + RS S + D+ + + +G+ R+ + R+ G R +
Sbjct: 138 YADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIEDKPRTSHRRSYSGSRSR 197
Query: 644 KRSRTRDSSWSRRSQTLSLSSESTSRSRSRSSDHGKRRSRSRNRDRYYLRNNYGSRYKWE 703
RSR R S SRRS S S SRSRSRS G+ RSRS+ R + +
Sbjct: 198 SRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGS 257
Query: 704 YTYYSRNKDRDGYESSYRRRTLSRAHYSRQSSSPEFRVQSFS---ERTNA------RKKN 754
++ +SR++ +D YE S R+ SR+ +++ + + +S S R+N+ K
Sbjct: 258 HS-HSRSRSKDEYEKS---RSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKAR 313
Query: 755 NHSERKYYYYERHRSRSLSSNRSRTASTGTD 785
+ S R RSRS S +RSR+ S+ D
Sbjct: 314 SVSPPPKRATSRSRSRSRSKSRSRSRSSSRD 344
Score = 57.4 bits (137), Expect = 7e-08
Identities = 45/125 (36%), Positives = 62/125 (49%), Gaps = 22/125 (17%)
Query: 582 RVYSPYNHRHRKRGRSRS-------SDSRSQSRSGHDQKNHRKHHGKKRMKSKRSRSRES 634
R YS R R R RSRS S SRS S+S ++ K + R K ++SRS+
Sbjct: 189 RSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSK 248
Query: 635 SRP---RGRRDKKRSRTRDSSWSRRSQTLSLSSESTSRSRSRS-SDHGKRRSRSRNRDRY 690
S+P RG RSR++D +S SRSRSRS ++GK +S++R R
Sbjct: 249 SKPKSDRGSHSHSRSRSKDE-----------YEKSRSRSRSRSPKENGKGDIKSKSRSRS 297
Query: 691 YLRNN 695
R+N
Sbjct: 298 QSRSN 302
Score = 43.5 bits (101), Expect = 0.001
Identities = 57/216 (26%), Positives = 86/216 (39%), Gaps = 26/216 (12%)
Query: 638 RGRRDKKRSRTRDSSWSRRSQTLSLSSESTSRSRSRSSDHGKRRSRSRNRDRYYLRNNYG 697
R D KR+ + + + L + S RS + RSRSR+R R R+
Sbjct: 154 RSYSDMKRALDKLDGTEINGRNIRLIEDKPRTSHRRS--YSGSRSRSRSRRRSRSRSRRS 211
Query: 698 SRYKWEYTYYSRNKDRDGYESSYRRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHS 757
SR + SR++ R + R R+ R S+ S P+ + R ++HS
Sbjct: 212 SRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPK----------SDRGSHSHS 261
Query: 758 -ERKYYYYERHRSRSLSSNRSRTASTGTDRVRNEKPGGKRKYKTRHLEGTNEVAQPSREF 816
R YE+ RSRS RSR+ N K K K ++R +N P
Sbjct: 262 RSRSKDEYEKSRSRS----RSRSPK------ENGKGDIKSKSRSRSQSRSN---SPLPVP 308
Query: 817 ASKAKDSHYQKSSSKLDGNYKNESDTFSDSRSSDRE 852
SKA+ + ++ S + S SRSS R+
Sbjct: 309 PSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSRD 344
Score = 41.6 bits (96), Expect = 0.004
Identities = 66/271 (24%), Positives = 107/271 (39%), Gaps = 31/271 (11%)
Query: 597 SRSSDSRSQSRSGHDQKNHRK--HHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWS 654
SR +D +G + R H + + + S S G +R+ RD
Sbjct: 45 SRDADDAVYELNGKELCGERVIVEHARGPRRDRDGYSYGSRSGGGGYSSRRTSGRDKYGP 104
Query: 655 --RRSQTLSLSSESTSRSRSRSSDHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKD 712
R L + + S+ S D ++ D + R N G Y+ R D
Sbjct: 105 PVRTEYRLIVENLSSRCSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALD 164
Query: 713 R-DGYESSYRRRTL----SRAHYSRQSSSPEFRVQSFSERTNARKKNNHSERKYYYYERH 767
+ DG E + R L R + R S R +S R +R ++ S R
Sbjct: 165 KLDGTEINGRNIRLIEDKPRTSHRRSYSGSRSRSRS---RRRSRSRSRRSSRS------- 214
Query: 768 RSRSLSSNRSRTASTGTDRVRNEKPGGKRKYKTRHLEGTNEVAQPSREFASKAKDSHYQK 827
RSRS+S +RSR+ S R R+ G K + K++ ++ + S++KD Y+K
Sbjct: 215 RSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSR--SRSKD-EYEK 271
Query: 828 SSSKL---------DGNYKNESDTFSDSRSS 849
S S+ G+ K++S + S SRS+
Sbjct: 272 SRSRSRSRSPKENGKGDIKSKSRSRSQSRSN 302
Score = 38.9 bits (89), Expect = 0.026
Identities = 56/252 (22%), Positives = 92/252 (36%), Gaps = 33/252 (13%)
Query: 672 SRSSDHGKRRSRSRNRDRY---------YLRNNYGSRYKW-----------EYTYYSRNK 711
SRS G R+ RD+Y + N SR W E TY +K
Sbjct: 84 SRSGGGGYSSRRTSGRDKYGPPVRTEYRLIVENLSSRCSWQDLKDFMRQAGEVTYADAHK 143
Query: 712 DRDGY------ESSYRRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSERKYYYYE 765
+R S +R L + + + R+ RT+ R+ + S +
Sbjct: 144 ERTNEGVIEFRSYSDMKRALDKLD-GTEINGRNIRLIEDKPRTSHRRSYSGSRSRSRSRR 202
Query: 766 RHRSRSL--SSNRSRTASTGTDRVRNEKPGGKRKYKTRHLEGTNEVAQPSREFASKAKDS 823
R RSRS S +RSR+ S R R+ G R + ++P + + S
Sbjct: 203 RSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPK---SDRGSHS 259
Query: 824 HYQKSSSKLDGNYKNESDTFSDSRSSDRETKHKRRKR-KTRSLSVEIVYEGKATDTTKHH 882
H + S ++ S + S + + K K R R ++RS S V KA +
Sbjct: 260 HSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPPP 319
Query: 883 KKKKKKHKKKHK 894
K+ + + + +
Sbjct: 320 KRATSRSRSRSR 331
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.127 0.363
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,363,936
Number of Sequences: 37866
Number of extensions: 1982294
Number of successful extensions: 18833
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 310
Number of HSP's successfully gapped in prelim test: 562
Number of HSP's that attempted gapping in prelim test: 9111
Number of HSP's gapped (non-prelim): 3729
length of query: 1045
length of database: 18,247,518
effective HSP length: 113
effective length of query: 932
effective length of database: 13,968,660
effective search space: 13018791120
effective search space used: 13018791120
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.