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Search of human proteins with 125490354
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|125490354 spermatogenesis associated 1 [Homo sapiens]
(459 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|125490354 spermatogenesis associated 1 [Homo sapiens] 904 0.0
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 55 2e-07
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 51 3e-06
gi|118498368 kinectin 1 isoform c [Homo sapiens] 50 4e-06
gi|71061468 centromere protein E [Homo sapiens] 47 5e-05
gi|31982906 cingulin-like 1 [Homo sapiens] 45 1e-04
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 45 2e-04
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 44 2e-04
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 44 2e-04
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 44 2e-04
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 44 2e-04
gi|34577114 cytomatrix protein p110 [Homo sapiens] 44 2e-04
gi|221219020 NYD-SP11 protein [Homo sapiens] 44 3e-04
gi|82880656 coiled-coil domain containing 46 isoform a [Homo sap... 44 4e-04
gi|29171755 PTPRF interacting protein alpha 2 [Homo sapiens] 44 4e-04
gi|58530840 desmoplakin isoform I [Homo sapiens] 42 0.001
gi|118918407 spectrin repeat containing, nuclear envelope 2 isof... 42 0.001
gi|118918403 spectrin repeat containing, nuclear envelope 2 isof... 42 0.001
gi|5174457 kinetochore associated 2 [Homo sapiens] 42 0.001
gi|225579095 S-phase cyclin A-associated protein in the ER isofo... 41 0.002
gi|225579092 S-phase cyclin A-associated protein in the ER isofo... 41 0.002
gi|45935391 coiled-coil domain containing 69 [Homo sapiens] 41 0.002
gi|56961680 coiled-coil domain containing 147 [Homo sapiens] 41 0.002
gi|50083279 centrosome protein 4 [Homo sapiens] 41 0.003
gi|41872583 Rho-associated, coiled-coil containing protein kinas... 40 0.003
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 40 0.003
gi|115511012 coiled-coil domain containing 136 [Homo sapiens] 40 0.003
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 40 0.004
gi|21735548 centrosomal protein 2 [Homo sapiens] 40 0.004
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 40 0.004
>gi|125490354 spermatogenesis associated 1 [Homo sapiens]
Length = 459
Score = 904 bits (2336), Expect = 0.0
Identities = 459/459 (100%), Positives = 459/459 (100%)
Query: 1 MKKDKKRNKIPIDNYPIQTLVNMSLNPSRPSSSELVELHVFYVPEGSWNYKLNTISTEVV 60
MKKDKKRNKIPIDNYPIQTLVNMSLNPSRPSSSELVELHVFYVPEGSWNYKLNTISTEVV
Sbjct: 1 MKKDKKRNKIPIDNYPIQTLVNMSLNPSRPSSSELVELHVFYVPEGSWNYKLNTISTEVV 60
Query: 61 NKFISAGFLRVSPQLTLRALRERLGEFLGEDAIAEKFLFLKCIGNNLAVVKEKQESELKL 120
NKFISAGFLRVSPQLTLRALRERLGEFLGEDAIAEKFLFLKCIGNNLAVVKEKQESELKL
Sbjct: 61 NKFISAGFLRVSPQLTLRALRERLGEFLGEDAIAEKFLFLKCIGNNLAVVKEKQESELKL 120
Query: 121 KSFAPPYALQPELYLLPVMDHLGNVYSPSTVILDERQTNNGVNEADGTIHRPISVTLFKE 180
KSFAPPYALQPELYLLPVMDHLGNVYSPSTVILDERQTNNGVNEADGTIHRPISVTLFKE
Sbjct: 121 KSFAPPYALQPELYLLPVMDHLGNVYSPSTVILDERQTNNGVNEADGTIHRPISVTLFKE 180
Query: 181 ELGRDPSLLENTLKELPNKNQEEAGGKATAEKSQIAKNQIGNSELPGSLEDSNNDCFGTK 240
ELGRDPSLLENTLKELPNKNQEEAGGKATAEKSQIAKNQIGNSELPGSLEDSNNDCFGTK
Sbjct: 181 ELGRDPSLLENTLKELPNKNQEEAGGKATAEKSQIAKNQIGNSELPGSLEDSNNDCFGTK 240
Query: 241 KSQCLWENEDDTAISRRQDNQTAEKEYITLPDHPSLPCQPVLSSGITDISLLQTEREKII 300
KSQCLWENEDDTAISRRQDNQTAEKEYITLPDHPSLPCQPVLSSGITDISLLQTEREKII
Sbjct: 241 KSQCLWENEDDTAISRRQDNQTAEKEYITLPDHPSLPCQPVLSSGITDISLLQTEREKII 300
Query: 301 KQMKQVKEERRYLERNREELVKTVEKLFEQSKLKRYHAYNGWKKKYLETKKVTASMEEVL 360
KQMKQVKEERRYLERNREELVKTVEKLFEQSKLKRYHAYNGWKKKYLETKKVTASMEEVL
Sbjct: 301 KQMKQVKEERRYLERNREELVKTVEKLFEQSKLKRYHAYNGWKKKYLETKKVTASMEEVL 360
Query: 361 TKLREDLELYYKKLLMQLEAREIKMRPKNLANITDSKNYLIIQITEVQHAIDQLKRKLDT 420
TKLREDLELYYKKLLMQLEAREIKMRPKNLANITDSKNYLIIQITEVQHAIDQLKRKLDT
Sbjct: 361 TKLREDLELYYKKLLMQLEAREIKMRPKNLANITDSKNYLIIQITEVQHAIDQLKRKLDT 420
Query: 421 DKMKLIVEVKMRKQAVSDLRTLKTELAQKKKIIHLYNLN 459
DKMKLIVEVKMRKQAVSDLRTLKTELAQKKKIIHLYNLN
Sbjct: 421 DKMKLIVEVKMRKQAVSDLRTLKTELAQKKKIIHLYNLN 459
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 54.7 bits (130), Expect = 2e-07
Identities = 69/309 (22%), Positives = 134/309 (43%), Gaps = 50/309 (16%)
Query: 154 DERQTNNGVNEA-DGTIHRPISVTLFKEELGRDPSLLENTLKELPNKNQEE---AGGKAT 209
+E+Q +NE + + + + EL ++L+ T EL NK Q++ A +
Sbjct: 953 EEQQLQGNINELKQSSEQKKKQIEALQGEL--KIAVLQKT--ELENKLQQQLTQAAQELA 1008
Query: 210 AEKSQIAKNQIGNSELPGSLEDSNNDCFGTKKSQCLWENEDDTAISRRQDNQTAEKEYIT 269
AEK +I+ Q + + + +D +G + ++ RQD ++ E E ++
Sbjct: 1009 AEKEKISVLQNNYEKSQETFKQLQSDFYG----------RESELLATRQDLKSVE-EKLS 1057
Query: 270 LPDHPSLPCQPVLSSGITDISLLQTEREKIIKQMKQVK----EERRYLERNREELVKTVE 325
L Q L S I + K+I+++K K ++ E+ +E K ++
Sbjct: 1058 L-------AQEDLISNRNQIG----NQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQ 1106
Query: 326 KLFEQSKLKRYHAYNGWKKKYLETKKVTASMEEVLTKLREDLELYYKKLLMQLEAREIKM 385
+ ++ LK N K K E +++ E+ +TKL E+L+ + + +
Sbjct: 1107 DIQKEKSLKEKELVNE-KSKLAEIEEIKCRQEKEITKLNEELKSHKLESI---------- 1155
Query: 386 RPKNLANITDSKNYLIIQITEVQHAIDQLKRKLDTDKMKLIVEVKMRKQAVSDLRTLKTE 445
K + N+ D+K LI Q E+Q D LK ++ +K + ++ Q + LK E
Sbjct: 1156 --KEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQI---LKDQVKKEEEELKKE 1210
Query: 446 LAQKKKIIH 454
+K+ +H
Sbjct: 1211 FIEKEAKLH 1219
Score = 39.3 bits (90), Expect = 0.008
Identities = 49/214 (22%), Positives = 98/214 (45%), Gaps = 27/214 (12%)
Query: 247 ENEDDTAISRRQDNQTAEKEYITLPDHPSLPCQPVLSSGITDISLLQTEREKIIKQMKQV 306
+N DTA + QD Q + T D + Q Q ++ +K+
Sbjct: 666 QNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDK-----------QEHCSQLESHLKEY 714
Query: 307 KEERRYLERNREELVKTVEKLFEQSKLKRYHAYNGWKKKYLETKKVTASMEEVLTKLRED 366
KE+ LE+ EEL ++KL E L+ + + + +++ +E T+L +
Sbjct: 715 KEKYLSLEQKTEELEGQIKKL-EADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQ 773
Query: 367 LELYYK-----KLLMQLEAREIKMRPKNLANITDSKNYL------IIQITEVQHAIDQLK 415
LE+ + +L +Q ++ ++ + L + K L + Q T++QH ++L
Sbjct: 774 LEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQH--EELN 831
Query: 416 RKLDTDKMKLIVEVKMRKQA-VSDLRTLKTELAQ 448
++ T +L +VKM K+A +++L T+K +L++
Sbjct: 832 NRIQTTVTEL-QKVKMEKEALMTELSTVKDKLSK 864
Score = 37.0 bits (84), Expect = 0.037
Identities = 55/240 (22%), Positives = 106/240 (44%), Gaps = 26/240 (10%)
Query: 228 SLEDSNNDCFGTKKSQCLWENEDDTAISRR-QDNQTAEKEYITLPDHPSLPCQPVLSSGI 286
++ D+ ND +S + +D T + + QD Q + KE + L +
Sbjct: 62 AVHDAGNDSGHGGESNLALKRDDVTLLRQEVQDLQASLKEEKWYSEE--------LKKEL 113
Query: 287 TDISLLQTEREKIIKQMKQVKEERRYLERNREEL------VKTVEKLFEQSKLKRYHAYN 340
LQ + K + E + LE+ EE +K ++ LFEQ +
Sbjct: 114 EKYQGLQQQEAKPDGLVTDSSAELQSLEQQLEEAQTENFNIKQMKDLFEQKAAQLATEIA 173
Query: 341 GWKKKYLETKKVTASMEEVLTKLREDLELYYKKLLMQLEAREIKMRPKNLANITDSKNYL 400
K KY E + + + E+ +T+L E EL + ++Q E+ RP + ++ K L
Sbjct: 174 DIKSKYDEERSLREAAEQKVTRLTE--ELNKEATVIQDLKTELLQRP-GIEDVAVLKKEL 230
Query: 401 IIQITEVQHAIDQ--LKRKLDTDKMKLIVEVKMRKQAVSD--LRTLKTELAQKKKIIHLY 456
+ +VQ +D L+R+ +++K+K + + A S+ + L++ELA+ + + +Y
Sbjct: 231 V----QVQTLMDNMTLERERESEKLKDECKKLQSQYASSEATISQLRSELAKGPQEVAVY 286
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 50.8 bits (120), Expect = 3e-06
Identities = 67/281 (23%), Positives = 116/281 (41%), Gaps = 31/281 (11%)
Query: 179 KEELGRDPSLLENTLKELPNKNQEEAGGKATAEKSQIAKNQIGNSELPGSLEDSNNDCFG 238
KEEL R E K EE EK+ + +E +L D+ C G
Sbjct: 864 KEELARS---------EARRKELEEKMVSLLQEKNDLQLQVQSETE---NLMDAEERCEG 911
Query: 239 TKKSQCLWENEDDTAISRRQDNQTAEKEYITLPDHPSLPCQPVLSSGITDISLLQTEREK 298
KS+ L E + R ++ + E + + C L I D+ L T+ EK
Sbjct: 912 LIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSS-LKRDIDDLELTLTKVEK 970
Query: 299 ----IIKQMKQVKEERRYLERNREELVKTVEKLFE--QSKLKRYHA----YNGWKKKYLE 348
++K + EE LE N +L K + L E Q L NG K +
Sbjct: 971 EKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAK 1030
Query: 349 TKKVTASMEEVLT---KLREDLELYYKKLLMQLEAREIKMRPKNLANITDSKNYLIIQIT 405
++ T +E L KLR DLE +KL ++KM +++ ++ + K + ++
Sbjct: 1031 LEQQTDDLEGSLEQEKKLRADLERAKRKL-----EGDLKMSQESIMDLENDKQQIEEKLK 1085
Query: 406 EVQHAIDQLKRKLDTDKMKLIVEVKMRKQAVSDLRTLKTEL 446
+ + + QL+ K+D +++ + K K+ + + L+ E+
Sbjct: 1086 KKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEI 1126
Score = 31.2 bits (69), Expect = 2.1
Identities = 33/158 (20%), Positives = 69/158 (43%), Gaps = 15/158 (9%)
Query: 294 TEREKIIKQMKQVKEERRYLERNREELVKTVEKLFEQSKLKRYHAYNGWKKKYLETKKVT 353
T+ + +++K+ ++ +LER ++ L +TV+ L + A G KK+
Sbjct: 1764 TDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQ-------I 1816
Query: 354 ASMEEVLTKLREDLELYYKK---LLMQLEAREIKMRPKNLANITDSKNYLIIQITEVQHA 410
+E + +L +L++ K+ L E K++ D KN I +Q
Sbjct: 1817 QKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKN-----ILRLQDL 1871
Query: 411 IDQLKRKLDTDKMKLIVEVKMRKQAVSDLRTLKTELAQ 448
+D+L+ K+ + K + + +S R ++ EL +
Sbjct: 1872 VDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEE 1909
>gi|118498368 kinectin 1 isoform c [Homo sapiens]
Length = 1300
Score = 50.1 bits (118), Expect = 4e-06
Identities = 63/291 (21%), Positives = 128/291 (43%), Gaps = 32/291 (10%)
Query: 180 EELGRDPSLLENTLKELPNKNQEEAGGKATAEKSQIAKNQIGNS--ELPGSLEDSNNDCF 237
++L + L+ ++E+ N +EA + E+ +I + N L L++ +D
Sbjct: 898 QDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDL- 956
Query: 238 GTKKSQCLWENEDDTAISRRQDNQTAEKEY---ITLPDHPSLPCQPVLSSGITDISLLQT 294
+ K+Q L + +D+ + + Q Q ++ Y + P H L V+S +IS L
Sbjct: 957 -SSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEEL--LKVISEREKEISGLWN 1013
Query: 295 E----REKIIKQMKQVKEERRYLERNREELVKTVEKLFEQSKLKRYHAYNGW----KKKY 346
E ++ + Q K+ E ++ +E E + ++KLF + + +Y W +KK
Sbjct: 1014 ELDSLKDAVEHQRKKNNERQQQVEAVELEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKA 1073
Query: 347 LETKKVTASMEEVLT---KLREDLELYYKKLLMQLEAREIK--------MRPKNLANITD 395
E T+ EEV KL+E E++ L+QLE + K + K ++
Sbjct: 1074 KECMAGTSGSEEVKVLEHKLKEADEMH---TLLQLECEKYKSVLAETEGILQKLQRSVEQ 1130
Query: 396 SKNYLIIQITEVQHAIDQLKRKLDTDKMKLIVEVKMRKQAVSDLRTLKTEL 446
+N +++ E I Q++ + + +L ++ + + +LR + L
Sbjct: 1131 EENKWKVKVDESHKTIKQMQSSFTSSEQEL-ERLRSENKDIENLRREREHL 1180
Score = 31.6 bits (70), Expect = 1.6
Identities = 34/180 (18%), Positives = 77/180 (42%), Gaps = 32/180 (17%)
Query: 283 SSGITDISLLQ---TEREKIIKQMKQVKEERRYLERNREELVKTVEKLFEQSKLKRYHAY 339
+SG ++ +L+ E +++ ++ E+ + + E +++ +++ EQ +
Sbjct: 1080 TSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEE------- 1132
Query: 340 NGWKKKYLETKKVTASMEEVLTKLREDLELYYKKLLMQLEAREIKMRPKNLANITDSKNY 399
N WK K E+ K M+ T ++LE ++ K++ N+ + +
Sbjct: 1133 NKWKVKVDESHKTIKQMQSSFTSSEQELE-------------RLRSENKDIENLRREREH 1179
Query: 400 LIIQITEVQ-------HAIDQLKRKLDTDKMKLIVEVKMRKQAVSDLRTLK--TELAQKK 450
L +++ + + + +LK +L+ KL E R++ DL + EL Q K
Sbjct: 1180 LEMELEKAEMERSTYVTEVRELKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELIQSK 1239
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 46.6 bits (109), Expect = 5e-05
Identities = 68/306 (22%), Positives = 135/306 (44%), Gaps = 31/306 (10%)
Query: 155 ERQTNNGVNEADGTIHRPISVTLFKEELGRDPSLLENTLKELPNKNQEEAGGKATAEKSQ 214
+++ N V E + I ++ EL PS +E KE+ +K++E T+EK +
Sbjct: 726 QKELNKEVEENEALREEVILLS----ELKSLPSEVERLRKEIQDKSEELH--IITSEKDK 779
Query: 215 IAKNQIGN-SELPGSLEDSNNDCFGTKKSQCLWENEDDTAISRRQDNQTAEKEYITLPDH 273
+ + S + G LE+ +Q +++ D + + + E++Y + +
Sbjct: 780 LFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEE 839
Query: 274 PSLPCQPVLSSGITDISLLQTEREKIIKQMKQVKEERRYL-----ERNRE--ELVKTVEK 326
Q +++ L E +K + +K E Y E+ RE E + +E+
Sbjct: 840 NERMNQEIVN--------LSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQ 891
Query: 327 LFEQSKLKRYHAYNGWKKKYLETKKVTASMEEVLTKLREDLELYYKKLLMQLEAREIKMR 386
L EQ + + ++K L T+K+ ++EEV T +E +L + +Q+E ++K
Sbjct: 892 LKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLK-- 949
Query: 387 PKNLANITDSKNYLIIQITEVQHAIDQLKR---KLDTDKMKLIVEVKMRKQAVSDLRTLK 443
++I D+ N I ++++A++ LK+ ++T K K+ EV + K
Sbjct: 950 ----SDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETK 1005
Query: 444 TELAQK 449
E QK
Sbjct: 1006 DEFQQK 1011
Score = 35.8 bits (81), Expect = 0.083
Identities = 38/133 (28%), Positives = 63/133 (47%), Gaps = 18/133 (13%)
Query: 302 QMKQVKEERRYLERNREELVKTVEKLFEQSKLKRYHAYNGWKKKYLETKK-------VTA 354
+MK V +E+ L+R +E L ++L E +K A K+LET++
Sbjct: 1436 EMKSVAKEKDDLQRLQEVLQSESDQLKEN--IKEIVA------KHLETEEELKVAHCCLK 1487
Query: 355 SMEEVLTKLREDL---ELYYKKLLMQLEAREIKMRPKNLANITDSKNYLIIQITEVQHAI 411
EE + +LR +L E + QLEA K++ K + + I QI+EVQ +
Sbjct: 1488 EQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKV 1547
Query: 412 DQLKRKLDTDKMK 424
++LK+ + K K
Sbjct: 1548 NELKQFKEHRKAK 1560
Score = 34.7 bits (78), Expect = 0.19
Identities = 37/168 (22%), Positives = 76/168 (45%), Gaps = 18/168 (10%)
Query: 297 EKIIKQMKQVKEERRYLERNREELVKTVEKLFEQSKLKRYHAYNGWKKKYLET------K 350
EK+ ++ +Q++E+++ L +EE+ + +K+ E LK +++ET +
Sbjct: 1127 EKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQ 1186
Query: 351 KVTASMEEV--LTKLREDLELYYKKLLMQLEAREIKMRPKNLANITDSKNYLI--IQITE 406
K+ + EEV +TK R+ L+ K + + +R + + I I + E
Sbjct: 1187 KLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIHLKE 1246
Query: 407 VQHAIDQLKRKLDTDKMKLIVEVKMRKQAVSDLRTLKTELAQKKKIIH 454
Q ID+L+R + ++I DL T+L ++ ++H
Sbjct: 1247 HQETIDELRRSVSEKTAQII--------NTQDLEKSHTKLQEEIPVLH 1286
Score = 34.7 bits (78), Expect = 0.19
Identities = 36/155 (23%), Positives = 74/155 (47%), Gaps = 41/155 (26%)
Query: 296 REKIIKQMKQVKEERRYLERNREELVKTVEKLFEQSKLKRYHAYNGWKKKYLETKKVTAS 355
REKI ++ Q+ + ++ L+++++EL K +++L +KK L+
Sbjct: 1944 REKISEKTIQISDIQKDLDKSKDELQKKIQEL---------------QKKELQ------- 1981
Query: 356 MEEVLTKLREDLELYYKK------LLMQLEAREIKMRPKNLAN--ITDSKNYLIIQITEV 407
L +++ED+ + +KK L Q EA+ + M+ + N +T + + +I V
Sbjct: 1982 ----LLRVKEDVNMSHKKINEMEQLKKQFEAQNLSMQSVRMDNFQLTKKLHESLEEIRIV 2037
Query: 408 QHAIDQLKRKLDTDKMKLIVEVKMRKQAVSDLRTL 442
D+L+R ++ KM+ R Q ++ LR +
Sbjct: 2038 AKERDELRRIKESLKME-------RDQFIATLREM 2065
Score = 31.2 bits (69), Expect = 2.1
Identities = 55/298 (18%), Positives = 126/298 (42%), Gaps = 36/298 (12%)
Query: 190 ENTLKELPNKNQEEAGGKATAEKSQIAKNQIGNSELPGSLEDSNNDCFGTKKSQCLWENE 249
E T+ EL E+ +T +K A N +++ E F K+ + E
Sbjct: 1490 EETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQ--FNIKQISEVQEKV 1547
Query: 250 DDTAISRRQDNQTAEKEYITLPDHPSLPCQPVLSSGITDISLLQTEREKIIKQMKQVKEE 309
++ + + ++++ A+ + + L L +I ++ E+E++ + + ++ E
Sbjct: 1548 NE--LKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIE 1605
Query: 310 RRYLERNREELV--------------------KTVEKLFEQSKLKRYHAYNGWKKKYLET 349
R L+ N +E+V +T EK+ E LK + +ET
Sbjct: 1606 RDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIET 1665
Query: 350 KKVT------ASMEEV--LTKLREDLELYYKKLLMQLEAREIKMRPKNLANITDSKNYLI 401
+ + ++EE+ +TK R+DL + L ++ + + +R ++ + I
Sbjct: 1666 ENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKI 1725
Query: 402 I--QITEVQHAIDQLKRKLDTDKMKLIVEVKMRKQAVSD-LRTLKTELAQKKKIIHLY 456
+ + E Q ID+L R + ++K I ++ + +D L+ ++ ++ +I H++
Sbjct: 1726 VHMHLKEHQETIDKL-RGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMH 1782
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 45.1 bits (105), Expect = 1e-04
Identities = 64/262 (24%), Positives = 101/262 (38%), Gaps = 75/262 (28%)
Query: 188 LLENTLKELPNKNQEEAGGKATA--EKSQIAKNQIGNSELPGSLEDSNNDCFGTKKSQCL 245
+L N LKE N + K EK Q K S GS + +N C T + + L
Sbjct: 558 ILYNYLKEGSTDNDDATKRKVNLVFEKIQTLK-----SRAAGSAQGNNQACNSTSEVKDL 612
Query: 246 WENEDDTAISRRQDNQTAEKEYITLPDHPSLPCQPVLSSGITDISLLQTEREKIIKQMKQ 305
E + I +++ LQ + + +K +
Sbjct: 613 LEQKSKLTI---------------------------------EVAELQRQLQLEVKNQQN 639
Query: 306 VKEERRYLERNREEL-VKTVEKLFEQSKLKRYHAYNGWKKKYLETKKVTASMEEVLTKLR 364
+KEER + N EEL + EK+ E S L++ +EE +LR
Sbjct: 640 IKEERERMRANLEELRSQHNEKVEENSTLQQ-------------------RLEESEGELR 680
Query: 365 EDLELYYKKLLMQLEAREIKM-RPKNLANITDSKNYLIIQITEVQHAIDQLKRKLDTDKM 423
++LE E ++KM R ++ I D ++ Q++E+ +D KR D +K
Sbjct: 681 KNLE----------ELFQVKMEREQHQTEIRDLQD----QLSEMHDELDSAKRSEDREKG 726
Query: 424 KLIVEVKMRKQAVSDLRTLKTE 445
LI E+ KQ + DL K E
Sbjct: 727 ALIEELLQAKQDLQDLLIAKEE 748
Score = 38.9 bits (89), Expect = 0.010
Identities = 88/437 (20%), Positives = 174/437 (39%), Gaps = 76/437 (17%)
Query: 70 RVSPQLTLRALRERLGEFLGE------------DAIAEKFLFLKCIGNNLAVVKEKQESE 117
R Q +R L+++L E E A+ E+ L K +L + KE+QE
Sbjct: 693 REQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDL 752
Query: 118 LKLKS---FAPPYALQPELYLLPV-MDHLGNVYSPSTVILDERQTNNGVNEADGTIHRPI 173
L+ + A AL+ E+ MD L Y L E V EA +
Sbjct: 753 LRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRE-----SVEEATKNVEVLA 807
Query: 174 SVTLFKEELGRDPSLLENTLKELPNKNQEEAGGKATAEKSQIAKNQIGNSELPGSLEDSN 233
S + E+ D + E +K L +N++ G E+ ++L +ED
Sbjct: 808 SRSNTSEQ---DQAGTEMRVKLLQEENEKLQGRSEELERRV--------AQLQRQIEDLK 856
Query: 234 NDCFGTKKSQCLWENE----DDTAISRRQDNQTAEKEYITLPDHPSLPCQPVLSSGITDI 289
D K++ +E E ++ + R++ + A L + Q LS +
Sbjct: 857 GDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEA-AQGNLSQTTQEQ 915
Query: 290 SLLQTEREKIIKQMKQVKEERRYLERNREELVKTVEKLFE----------------QSKL 333
L + ++ +Q +Q++ + +E R L KT+EKL + Q++L
Sbjct: 916 KQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQL 975
Query: 334 KRYHAYN---------GWKKKYLETKK---VTASMEEVLTKLREDLELYY--------KK 373
Y N K+K LE +K M++ + + E+L Y K+
Sbjct: 976 DEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTKR 1035
Query: 374 LLMQLEAREIKMRPKNLANITDSKNYLIIQITEVQHAIDQLKRKLDTDKMKLIVEVKMRK 433
L++ ++++ + +++ D ++ L+ Q ++ + QL+ +L+ ++ + +
Sbjct: 1036 QLLEQTLKDLEYELEAKSHLKDDRSRLVKQ---MEDKVSQLEMELEEERNNSDLLSERIS 1092
Query: 434 QAVSDLRTLKTELAQKK 450
++ + L+ EL Q++
Sbjct: 1093 RSREQMEQLRNELLQER 1109
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 44.7 bits (104), Expect = 2e-04
Identities = 63/306 (20%), Positives = 132/306 (43%), Gaps = 51/306 (16%)
Query: 180 EELGRDPSLLENTLKELPNKNQEEAGGKATAEKSQIAKNQIGNSELPGSLEDSNNDC--- 236
EE+ + L++ L E+ N N+ K ++ N L +E+ + C
Sbjct: 848 EEIQSEKEALQSDLLEMKNANE---------------KTRLENQNLLIQVEEVSQTCSKS 892
Query: 237 -FGTKKSQC-LWENEDDTAISRRQDNQTAEKEYITLPDH----PSLPCQPV-----LSSG 285
+K +C + E+E+ + +++ + E I L D PS+ P+ L
Sbjct: 893 EIHNEKEKCFIKEHENLKPLLEQKELRDRRAELILLKDSLAKSPSVKNDPLSSVKELEEK 952
Query: 286 ITDISLLQTEREKIIKQMKQVK-EERRYLERNREELVKTVEKLFEQSKLKR--------- 335
I ++ E+E+ I ++K V + ++ L+ +R+E +TV++ E + ++
Sbjct: 953 IENLEKECKEKEEKINKIKLVAVKAKKELDSSRKE-TQTVKEELESLRSEKDQLSASMRD 1011
Query: 336 -YHAYNGWKKKYLETKKVTASMEEVLTKLREDLELYYKKLLMQLEAREIKMRPKNLAN-- 392
+K LE +K + ++ V + + E + L QL ++ N N
Sbjct: 1012 LIQGAESYKNLLLEYEKQSEQLD-VEKERANNFEHRIEDLTRQLRNSTLQCETINSDNED 1070
Query: 393 -------ITDSKNYLIIQITEVQHAIDQLKRKLDTDKMKLIVEVKMRKQAVSDLRTLKTE 445
+ + L +QI EVQ A + ++L+ +K++ ++K V++L L+ +
Sbjct: 1071 LLARIETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQKEQKIKEHATTVNELEELQVQ 1130
Query: 446 LAQKKK 451
L ++KK
Sbjct: 1131 LQKEKK 1136
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 44.3 bits (103), Expect = 2e-04
Identities = 65/292 (22%), Positives = 116/292 (39%), Gaps = 43/292 (14%)
Query: 190 ENTLKELPNKNQEEAGGKATAEKSQIAKNQIGNSELPGSLEDSNNDCFGTKKS------- 242
EN LKEL K+ + T EK+ + + +EL E+ K+
Sbjct: 872 ENELKELEQKHSQ-----LTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHE 926
Query: 243 -QCLWENEDDTAISRRQDNQTAEKEYITLPDH--------PSLPCQPVLSSGITDISLLQ 293
+ E E+D + + + ++ + L + L + V + I L+
Sbjct: 927 MEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEA--KIKKLE 984
Query: 294 TEREKIIKQMKQVKEERRYLERNREELVKTV----EKLFEQSKLKRYHA---------YN 340
E + Q ++ +ER+ LE +L + EK +KLK H
Sbjct: 985 DEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLK 1044
Query: 341 GWKKKYLETKKVTASMEEVLTKLRE---DLELYYKKLLMQLEAREIKMRPKNLANITDS- 396
+K E +K+ +E + E DL+ +L MQL +E +++ LA + D
Sbjct: 1045 KEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAA-LARLDDEI 1103
Query: 397 --KNYLIIQITEVQHAIDQLKRKLDTDKMKLIVEVKMRKQAVSDLRTLKTEL 446
KN + +I E++ I L+ LD+++ K ++ +L LKTEL
Sbjct: 1104 AQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTEL 1155
Score = 39.7 bits (91), Expect = 0.006
Identities = 61/298 (20%), Positives = 122/298 (40%), Gaps = 45/298 (15%)
Query: 179 KEELGRDPSLLENTLKELPNKNQEEAGGKATAEKSQIAKNQIGNSELPGSLEDSNNDCFG 238
KEEL R +L+ +++L + + EKS+ A + E+ LE+ ++
Sbjct: 1499 KEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRAL-ETQMEEMKTQLEELEDELQA 1557
Query: 239 TKKSQCLWE---------------NEDDTAISRRQDNQTAEKEYIT-LPDHP-----SLP 277
T+ ++ E D+ +R+ Q EY T L D +
Sbjct: 1558 TEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAA 1617
Query: 278 CQPVLSSGITDISLLQTE----REKIIKQMKQVKEERRYLERNREELVKTVEKLFEQSKL 333
+ L + D+ L RE+ IKQ+++++ + + +R E+ + +++F +K
Sbjct: 1618 AKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAK- 1676
Query: 334 KRYHAYNGWKKKYLETKKVTASMEEVLTKLREDLELYYK-KLLMQLEAREIKMRPKNLAN 392
E +K S+E L +L+EDL + + LE E+ + LA+
Sbjct: 1677 --------------ENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEEL---AEELAS 1719
Query: 393 ITDSKNYLIIQITEVQHAIDQLKRKLDTDKMKLIVEVKMRKQAVSDLRTLKTELAQKK 450
+N L + ++ I QL+ +L+ ++ + ++A L ELA ++
Sbjct: 1720 SLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATER 1777
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 44.3 bits (103), Expect = 2e-04
Identities = 65/292 (22%), Positives = 116/292 (39%), Gaps = 43/292 (14%)
Query: 190 ENTLKELPNKNQEEAGGKATAEKSQIAKNQIGNSELPGSLEDSNNDCFGTKKS------- 242
EN LKEL K+ + T EK+ + + +EL E+ K+
Sbjct: 879 ENELKELEQKHSQ-----LTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHE 933
Query: 243 -QCLWENEDDTAISRRQDNQTAEKEYITLPDH--------PSLPCQPVLSSGITDISLLQ 293
+ E E+D + + + ++ + L + L + V + I L+
Sbjct: 934 MEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEA--KIKKLE 991
Query: 294 TEREKIIKQMKQVKEERRYLERNREELVKTV----EKLFEQSKLKRYHA---------YN 340
E + Q ++ +ER+ LE +L + EK +KLK H
Sbjct: 992 DEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLK 1051
Query: 341 GWKKKYLETKKVTASMEEVLTKLRE---DLELYYKKLLMQLEAREIKMRPKNLANITDS- 396
+K E +K+ +E + E DL+ +L MQL +E +++ LA + D
Sbjct: 1052 KEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAA-LARLDDEI 1110
Query: 397 --KNYLIIQITEVQHAIDQLKRKLDTDKMKLIVEVKMRKQAVSDLRTLKTEL 446
KN + +I E++ I L+ LD+++ K ++ +L LKTEL
Sbjct: 1111 AQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTEL 1162
Score = 39.7 bits (91), Expect = 0.006
Identities = 61/298 (20%), Positives = 122/298 (40%), Gaps = 45/298 (15%)
Query: 179 KEELGRDPSLLENTLKELPNKNQEEAGGKATAEKSQIAKNQIGNSELPGSLEDSNNDCFG 238
KEEL R +L+ +++L + + EKS+ A + E+ LE+ ++
Sbjct: 1506 KEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRAL-ETQMEEMKTQLEELEDELQA 1564
Query: 239 TKKSQCLWE---------------NEDDTAISRRQDNQTAEKEYIT-LPDHP-----SLP 277
T+ ++ E D+ +R+ Q EY T L D +
Sbjct: 1565 TEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAA 1624
Query: 278 CQPVLSSGITDISLLQTE----REKIIKQMKQVKEERRYLERNREELVKTVEKLFEQSKL 333
+ L + D+ L RE+ IKQ+++++ + + +R E+ + +++F +K
Sbjct: 1625 AKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAK- 1683
Query: 334 KRYHAYNGWKKKYLETKKVTASMEEVLTKLREDLELYYK-KLLMQLEAREIKMRPKNLAN 392
E +K S+E L +L+EDL + + LE E+ + LA+
Sbjct: 1684 --------------ENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEEL---AEELAS 1726
Query: 393 ITDSKNYLIIQITEVQHAIDQLKRKLDTDKMKLIVEVKMRKQAVSDLRTLKTELAQKK 450
+N L + ++ I QL+ +L+ ++ + ++A L ELA ++
Sbjct: 1727 SLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATER 1784
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 44.3 bits (103), Expect = 2e-04
Identities = 65/292 (22%), Positives = 116/292 (39%), Gaps = 43/292 (14%)
Query: 190 ENTLKELPNKNQEEAGGKATAEKSQIAKNQIGNSELPGSLEDSNNDCFGTKKS------- 242
EN LKEL K+ + T EK+ + + +EL E+ K+
Sbjct: 879 ENELKELEQKHSQ-----LTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHE 933
Query: 243 -QCLWENEDDTAISRRQDNQTAEKEYITLPDH--------PSLPCQPVLSSGITDISLLQ 293
+ E E+D + + + ++ + L + L + V + I L+
Sbjct: 934 MEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEA--KIKKLE 991
Query: 294 TEREKIIKQMKQVKEERRYLERNREELVKTV----EKLFEQSKLKRYHA---------YN 340
E + Q ++ +ER+ LE +L + EK +KLK H
Sbjct: 992 DEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLK 1051
Query: 341 GWKKKYLETKKVTASMEEVLTKLRE---DLELYYKKLLMQLEAREIKMRPKNLANITDS- 396
+K E +K+ +E + E DL+ +L MQL +E +++ LA + D
Sbjct: 1052 KEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAA-LARLDDEI 1110
Query: 397 --KNYLIIQITEVQHAIDQLKRKLDTDKMKLIVEVKMRKQAVSDLRTLKTEL 446
KN + +I E++ I L+ LD+++ K ++ +L LKTEL
Sbjct: 1111 AQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTEL 1162
Score = 39.7 bits (91), Expect = 0.006
Identities = 61/298 (20%), Positives = 122/298 (40%), Gaps = 45/298 (15%)
Query: 179 KEELGRDPSLLENTLKELPNKNQEEAGGKATAEKSQIAKNQIGNSELPGSLEDSNNDCFG 238
KEEL R +L+ +++L + + EKS+ A + E+ LE+ ++
Sbjct: 1506 KEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRAL-ETQMEEMKTQLEELEDELQA 1564
Query: 239 TKKSQCLWE---------------NEDDTAISRRQDNQTAEKEYIT-LPDHP-----SLP 277
T+ ++ E D+ +R+ Q EY T L D +
Sbjct: 1565 TEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAA 1624
Query: 278 CQPVLSSGITDISLLQTE----REKIIKQMKQVKEERRYLERNREELVKTVEKLFEQSKL 333
+ L + D+ L RE+ IKQ+++++ + + +R E+ + +++F +K
Sbjct: 1625 AKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAK- 1683
Query: 334 KRYHAYNGWKKKYLETKKVTASMEEVLTKLREDLELYYK-KLLMQLEAREIKMRPKNLAN 392
E +K S+E L +L+EDL + + LE E+ + LA+
Sbjct: 1684 --------------ENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEEL---AEELAS 1726
Query: 393 ITDSKNYLIIQITEVQHAIDQLKRKLDTDKMKLIVEVKMRKQAVSDLRTLKTELAQKK 450
+N L + ++ I QL+ +L+ ++ + ++A L ELA ++
Sbjct: 1727 SLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATER 1784
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 44.3 bits (103), Expect = 2e-04
Identities = 65/292 (22%), Positives = 116/292 (39%), Gaps = 43/292 (14%)
Query: 190 ENTLKELPNKNQEEAGGKATAEKSQIAKNQIGNSELPGSLEDSNNDCFGTKKS------- 242
EN LKEL K+ + T EK+ + + +EL E+ K+
Sbjct: 872 ENELKELEQKHSQ-----LTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHE 926
Query: 243 -QCLWENEDDTAISRRQDNQTAEKEYITLPDH--------PSLPCQPVLSSGITDISLLQ 293
+ E E+D + + + ++ + L + L + V + I L+
Sbjct: 927 MEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEA--KIKKLE 984
Query: 294 TEREKIIKQMKQVKEERRYLERNREELVKTV----EKLFEQSKLKRYHA---------YN 340
E + Q ++ +ER+ LE +L + EK +KLK H
Sbjct: 985 DEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLK 1044
Query: 341 GWKKKYLETKKVTASMEEVLTKLRE---DLELYYKKLLMQLEAREIKMRPKNLANITDS- 396
+K E +K+ +E + E DL+ +L MQL +E +++ LA + D
Sbjct: 1045 KEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAA-LARLDDEI 1103
Query: 397 --KNYLIIQITEVQHAIDQLKRKLDTDKMKLIVEVKMRKQAVSDLRTLKTEL 446
KN + +I E++ I L+ LD+++ K ++ +L LKTEL
Sbjct: 1104 AQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTEL 1155
Score = 39.7 bits (91), Expect = 0.006
Identities = 61/298 (20%), Positives = 122/298 (40%), Gaps = 45/298 (15%)
Query: 179 KEELGRDPSLLENTLKELPNKNQEEAGGKATAEKSQIAKNQIGNSELPGSLEDSNNDCFG 238
KEEL R +L+ +++L + + EKS+ A + E+ LE+ ++
Sbjct: 1499 KEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRAL-ETQMEEMKTQLEELEDELQA 1557
Query: 239 TKKSQCLWE---------------NEDDTAISRRQDNQTAEKEYIT-LPDHP-----SLP 277
T+ ++ E D+ +R+ Q EY T L D +
Sbjct: 1558 TEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAA 1617
Query: 278 CQPVLSSGITDISLLQTE----REKIIKQMKQVKEERRYLERNREELVKTVEKLFEQSKL 333
+ L + D+ L RE+ IKQ+++++ + + +R E+ + +++F +K
Sbjct: 1618 AKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAK- 1676
Query: 334 KRYHAYNGWKKKYLETKKVTASMEEVLTKLREDLELYYK-KLLMQLEAREIKMRPKNLAN 392
E +K S+E L +L+EDL + + LE E+ + LA+
Sbjct: 1677 --------------ENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEEL---AEELAS 1719
Query: 393 ITDSKNYLIIQITEVQHAIDQLKRKLDTDKMKLIVEVKMRKQAVSDLRTLKTELAQKK 450
+N L + ++ I QL+ +L+ ++ + ++A L ELA ++
Sbjct: 1720 SLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATER 1777
>gi|34577114 cytomatrix protein p110 [Homo sapiens]
Length = 957
Score = 44.3 bits (103), Expect = 2e-04
Identities = 45/192 (23%), Positives = 95/192 (49%), Gaps = 32/192 (16%)
Query: 291 LLQTE-REKIIKQMKQVKEERRYLERNREELVKTVEK-----LFEQSKLKRYHAYNGWKK 344
+L TE RE+ IKQ++ K ++++ ++L + + K L Q+KL+ N K
Sbjct: 409 VLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCK 468
Query: 345 KYLETKKVTASMEEVLTKLREDLELYYKKLLMQLEARE--IKMRPKNLANITDSKNYLII 402
+++E K + + +E + L+ L ++LE +E + + K L ++T+ K L
Sbjct: 469 QHIEVLKESLTAKEQRAAI---LQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAG 525
Query: 403 QITEVQHAIDQLKRKLDT-------------DKMKLIVEVKMRKQAV--------SDLRT 441
+I +++ ++ +RK++ DK K + +K R +++ + L T
Sbjct: 526 EIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALAT 585
Query: 442 LKTELAQKKKII 453
L+ L++K++II
Sbjct: 586 LEEALSEKERII 597
Score = 35.0 bits (79), Expect = 0.14
Identities = 35/148 (23%), Positives = 69/148 (46%), Gaps = 12/148 (8%)
Query: 302 QMKQVKEERRYLERNREELVKTVEKLFEQSKLKRYHAYNGWKKKYLETKKVTA----SME 357
Q+KQ+ +E Y + V++L E K + + N KK E + +T
Sbjct: 704 QIKQLDKEASYYRDECGKAQAEVDRLLEILK-EVENEKNDKDKKIAELESLTLRHMKDQN 762
Query: 358 EVLTKLREDLELYYKKLLMQLEAREIKMRPKNLANITDSKNYLIIQITEVQHAIDQLKRK 417
+ + L+ + +L KK LE E++ R ++A+ N +QI E+ +A+++ +++
Sbjct: 763 KKVANLKHNQQLEKKKNAQLLE--EVRRREDSMAD-----NSQHLQIEELMNALEKTRQE 815
Query: 418 LDTDKMKLIVEVKMRKQAVSDLRTLKTE 445
LD K +L + + + L L+ E
Sbjct: 816 LDATKARLASTQQSLAEKEAHLANLRIE 843
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 43.9 bits (102), Expect = 3e-04
Identities = 75/327 (22%), Positives = 145/327 (44%), Gaps = 61/327 (18%)
Query: 180 EELGRDPSLLENTLKELPNKNQEEA---------GGKATAEKSQIAKNQIGNSELPGSLE 230
E+L ++ L K+L K ++ A GGK K+ +A+ ELP
Sbjct: 1649 EKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKV---EELPQ--R 1703
Query: 231 DSNNDCFGTKKSQCL----WENED----DTAISRRQDNQTAEKEYITLPDHPSLPCQPVL 282
+ N D + +Q L W+ E+ + +++ + EK+ + + + L
Sbjct: 1704 EQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKL 1763
Query: 283 SSGITDIS----LLQTEREKIIKQMKQVKEERRYLERNREELVKTVEKLFEQ-------- 330
S T ++ LL E+EK+ + +++ EE L R RE+L++ KL ++
Sbjct: 1764 SEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSM 1823
Query: 331 SKLKRYHAYNGWKKKYLETKKVTASMEEVLTKLREDLELYYKKLLMQLEAREIKMRPK-N 389
+L + KK + KK A +E L + +E+L LY K+ L + + ++++ K
Sbjct: 1824 EELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENL-LYNKERLTHSKKQLVQVKNKLG 1882
Query: 390 LAN---------ITDSKNYLI----------IQITEVQHAIDQLKRKLDTDKMKLIVEVK 430
+ N +T K +I ++ +V+ ++ + + KL +KMKL +E
Sbjct: 1883 MFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALE-- 1940
Query: 431 MRKQAVSDLRTLKTEL--AQKKKIIHL 455
K V + L+ EL A+++K ++L
Sbjct: 1941 --KAMVQGKKRLRGELDIAKEEKALNL 1965
Score = 35.8 bits (81), Expect = 0.083
Identities = 45/198 (22%), Positives = 89/198 (44%), Gaps = 23/198 (11%)
Query: 179 KEELGRDPSLLENTLKELPNK-----NQEEAGGKATAEKSQIAKNQ---IGNSELPGSLE 230
+ EL +D L ++L NK N+EE K T E+S++A+ I + E G +E
Sbjct: 2129 RSELTKDEKKLARKQRKLANKMRRMINKEE---KMTEEESKLARKHSEVILDDEEEGGIE 2185
Query: 231 DSNNDCFGTKKSQCLWENEDDTAISRR-QDNQTAEKEYITLPDHPSLPCQPVLSSGITDI 289
+ F ++ W + + ++ +++ + + +H S + +L
Sbjct: 2186 EEEVIPFLKRR----WRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQE 2241
Query: 290 SLLQTEREKIIKQMKQVKEERRYLERNREELVKTVEKLFEQSKLKRYHAYNGWKKKYLET 349
SL E E+ ++ ++ +EE R E R+E + EK E+ + ++ KKK E
Sbjct: 2242 SLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEK-------KKKKKEK 2294
Query: 350 KKVTASMEEVLTKLREDL 367
KK +E + + +E++
Sbjct: 2295 KKEEVQEKEEVFEEKEEI 2312
Score = 32.7 bits (73), Expect = 0.71
Identities = 30/144 (20%), Positives = 63/144 (43%), Gaps = 20/144 (13%)
Query: 292 LQTEREKIIKQMKQVKEERRYLERNREELVKTVEKL---------FEQSKLKRYHAYNGW 342
L E+EK+ ++ + + + L ++++LV+ KL E+ +
Sbjct: 1846 LAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKK 1905
Query: 343 KKKYLETKKVTASMEEVLTKLREDLELYYKKLLMQLEAREIKMRPKNLANITDSKNYLII 402
K+K ET+K +E+ L K +E L KL ++ + K R + +I + L +
Sbjct: 1906 KEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNL 1965
Query: 403 QITEVQHAIDQLKRKLDTDKMKLI 426
++ ++L +KM+L+
Sbjct: 1966 EM-----------KRLAEEKMRLV 1978
>gi|82880656 coiled-coil domain containing 46 isoform a [Homo
sapiens]
Length = 955
Score = 43.5 bits (101), Expect = 4e-04
Identities = 67/325 (20%), Positives = 133/325 (40%), Gaps = 40/325 (12%)
Query: 155 ERQTNNGVNEADGTIHRPIS------VTLFKEELGRDPSLLENTLKELPNKNQEEAGGKA 208
E+ T + N+ + +H ++ L K+ LLE+T L NK + E +
Sbjct: 345 EQSTESLNNDWEKKLHNAVAEMEQEKFDLQKQHTENIQELLEDTNVRL-NKMESEYMAQT 403
Query: 209 TAEKSQIAKNQIGNSELPGSLEDSNNDCFGTKKSQCLWENEDDTAISRRQD----NQTAE 264
+ I + + +L G E+SN + + E S Q+ T
Sbjct: 404 QSTNHMIKELEARVQQLTGEAENSNLQRQKLIQEKAELERCYQITCSELQEVKARRNTLH 463
Query: 265 KEYITLPDHPSLPCQPVLSSGITDISLLQTER-----------EKIIKQMKQVKEERRYL 313
KE L + + + + DI+LL+ E E++ + + Q+K++ +
Sbjct: 464 KEKDHLVNDYEQNMKLLQTKYDADINLLKQEHALSASKASSMIEELEQNVCQLKQQLQES 523
Query: 314 ERNREELVKTVEKLFEQSKLKRYHAYNGWKKKYLETKKVTASMEEVLTKLREDLELYYKK 373
E R++ ++ E F+ K H Y +K ++ L K +ED + KK
Sbjct: 524 ELQRKQQLRDQENKFQMEKSHLKHIY----------EKKAHDLQSELDKGKEDTQ---KK 570
Query: 374 LLMQLEAREIKMRPKNLANITDSKNYLIIQITEVQHAIDQLKRKLDTDKMKLIVEVKMRK 433
+ EA +K + + L +T+ + +Q + A+++ KR+++ + K+ E+K +
Sbjct: 571 IHKFEEA--LKEKEEQLTRVTEVQR---LQAQQADAALEEFKRQVELNSEKVYAEMKEQM 625
Query: 434 QAVSDLRTLKTELAQKKKIIHLYNL 458
+ V T L +K+ L+ L
Sbjct: 626 EKVEADLTRSKSLREKQSKEFLWQL 650
Score = 33.9 bits (76), Expect = 0.32
Identities = 31/159 (19%), Positives = 72/159 (45%), Gaps = 7/159 (4%)
Query: 304 KQVKEERRYLERNREELVKTVEKLFEQSKLKRYHAYNGWKKKYLETKKVTASMEEVLTKL 363
K+ + + L++ +E+ K + K E K K + + L+ ++ A++EE ++
Sbjct: 551 KKAHDLQSELDKGKEDTQKKIHKFEEALKEKEEQLTRVTEVQRLQAQQADAALEEFKRQV 610
Query: 364 REDLELYYKKLLMQLEAREIKMRPKNLANITDSKNYLIIQITEVQHAIDQ----LKRKLD 419
+ E Y ++ Q+E E + SK +L Q+ +++ +Q LK + +
Sbjct: 611 ELNSEKVYAEMKEQMEKVEADLTRSKSLREKQSKEFL-WQLEDIRQRYEQQIVELKLEHE 669
Query: 420 TDKMKLIVEVKMRKQAVSDLRTLKTELAQKKKIIHLYNL 458
+K L+ + K ++ +R + E+ +K + N+
Sbjct: 670 QEKTHLLQQHNAEKDSL--VRDHEREIENLEKQLRAANM 706
Score = 32.7 bits (73), Expect = 0.71
Identities = 42/166 (25%), Positives = 74/166 (44%), Gaps = 26/166 (15%)
Query: 292 LQTEREKIIKQMKQVKEERRYLERNREELVKTVEKLFEQSKLKRYHAYNGWKKKYLETKK 351
L+ E+EK ++Q E+ L R+ E ++ +EK + ++ + +KK+ +
Sbjct: 666 LEHEQEKT-HLLQQHNAEKDSLVRDHEREIENLEKQLRAANMEHENQIQEFKKR---DAQ 721
Query: 352 VTASMEEVLTKLREDLELYYKKLLMQL-EAREIKMRPKNLANITDSKNYLIIQITEVQHA 410
V A ME + KLRE+L + QL E ++ K A +H
Sbjct: 722 VIADMEAQVHKLREELINVNSQRKQQLVELGLLREEEKQRAT--------------REHE 767
Query: 411 IDQLKRKLDTDKMKL------IVEVKMR-KQAVSDLRTLKTELAQK 449
I K K +++KMK+ E +M ++A S L+ ++ E QK
Sbjct: 768 IVVNKLKAESEKMKIELKKTHAAETEMTLEKANSKLKQIEKEYTQK 813
>gi|29171755 PTPRF interacting protein alpha 2 [Homo sapiens]
Length = 1257
Score = 43.5 bits (101), Expect = 4e-04
Identities = 63/301 (20%), Positives = 123/301 (40%), Gaps = 28/301 (9%)
Query: 140 DHLGNVYSPSTVILDERQTNNGVNEADGTIHRPISVTLFKEELGRDPSLLENTLKELPNK 199
+HL + P + ++R +N ++ D T + + + E+ + + ++ L L ++
Sbjct: 240 EHLEGM-EPGQKVHEKRLSNGSIDSTDET-SQIVELQELLEKQNYEMAQMKERLAALSSR 297
Query: 200 NQEEAGGKATAEKSQIAKNQIGNS------ELPGSLEDSNNDCFGTKKSQCLWENEDDTA 253
E TA K I ++ E ED + T + + L + T+
Sbjct: 298 VGEVEQEAETARKDLIKTEEMNTKYQRDIREAMAQKEDME-ERITTLEKRYLSAQRESTS 356
Query: 254 ISRRQD---NQTAEKEYIT---------LPDHPSLPCQPVLSSGITDISLLQTEREKIIK 301
I D N+ A KE I L + L Q + + +L + E E +
Sbjct: 357 IHDMNDKLENELANKEAILRQMEEKNRQLQERLELAEQKLQQTMRKAETLPEVEAELAQR 416
Query: 302 QMKQVKEERRYLERNREELVKTVEKLFEQSKLKRYHAYNGWKKKYLETKKVTASMEEVLT 361
K E R+ N EE ++ +E E+ + A K K+++ +++ +LT
Sbjct: 417 IAALTKAEERH--GNIEERMRHLEGQLEEKNQELQRARQREKMNEEHNKRLSDTVDRLLT 474
Query: 362 KLREDLELYYKKLLMQLEAREIKMRP-----KNLANITDSKNYLIIQITEVQHAIDQLKR 416
+ E L+L+ K+ + LE + + ++ KNL K L +I +++ +DQLK
Sbjct: 475 ESNERLQLHLKERMAALEEKNVLIQESETFRKNLEESLHDKERLAEEIEKLRSELDQLKM 534
Query: 417 K 417
+
Sbjct: 535 R 535
>gi|58530840 desmoplakin isoform I [Homo sapiens]
Length = 2871
Score = 42.0 bits (97), Expect = 0.001
Identities = 54/271 (19%), Positives = 121/271 (44%), Gaps = 30/271 (11%)
Query: 159 NNGVNEADGTIHRPISVTLFKEELGRDPSLLENTLKELPNKNQEEAGGKATAEKSQIAKN 218
+ +NE+ I R S+T E L ++ +LE L+ L + + G++ A+ + A
Sbjct: 1693 SRSLNESKIEIERLQSLT---ENLTKEHLMLEEELRNLRLEYDDLRRGRSEADSDKNATI 1749
Query: 219 QIGNSELPGSLEDSNNDCFGTKKSQCLWENEDDTAISRRQDNQTAEKEYITLPDHPSLPC 278
EL L+ SNN T + Q L + + RQ+ + +K+ +L
Sbjct: 1750 L----ELRSQLQISNNR---TLELQGLINDLQRERENLRQEIEKFQKQ--------ALEA 1794
Query: 279 QPVLSSGITDISLLQTEREKIIKQMKQVKEERRYLERNREELVKTVEKLFEQSKLKR--- 335
+ + + ERE ++ ++K +++++ L+R +EL + L ++++K+
Sbjct: 1795 SNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKSTLEAETRVKQRLE 1854
Query: 336 ------YHAYNGWKKKYLETKKVTASME---EVLTKLREDLELYYKKLLMQLEAREIKMR 386
+ N WK +Y ++ +E E + + L ++L +++ E + R
Sbjct: 1855 CEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKRIEERCR 1914
Query: 387 PKNLANITDSKNYLIIQITEVQHAIDQLKRK 417
K + ++++ L + + Q ID+L+++
Sbjct: 1915 RKLEDSTRETQSQLETERSRYQREIDKLRQR 1945
Score = 31.2 bits (69), Expect = 2.1
Identities = 33/159 (20%), Positives = 72/159 (45%), Gaps = 11/159 (6%)
Query: 288 DISLLQTEREKIIKQMKQVKEERRYLERNREELVKTVEKLFEQSKLKRYHAYNGWKKKYL 347
DI+ Q +++ Q ++V+EE L+R E +KL E+ + R K++ +
Sbjct: 1555 DITRFQNSLKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMR----RSLKEQAI 1610
Query: 348 ETKKVTASMEEV-LTKLREDLELYYKKLLMQLEAREIKMRPKNLANITDSKNYLIIQITE 406
+ +T +E+ + K R + +L ++ ++ RE + + L ++ L Q+ +
Sbjct: 1611 KITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEALRRQLLQ 1670
Query: 407 VQHAIDQLK------RKLDTDKMKLIVEVKMRKQAVSDL 439
Q ++ Q +K DK + + E K+ + + L
Sbjct: 1671 EQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSL 1709
>gi|118918407 spectrin repeat containing, nuclear envelope 2 isoform
5 [Homo sapiens]
Length = 6907
Score = 42.0 bits (97), Expect = 0.001
Identities = 41/153 (26%), Positives = 69/153 (45%), Gaps = 16/153 (10%)
Query: 304 KQVKEERRYLERNRE-----ELVKTVEKLFEQSKLKRYHAYNGWKKKYLETKKVTASMEE 358
+ +K ++ + N E ++ K VEKL Q ++ A K L+ V SMEE
Sbjct: 714 QNIKAGEKHEKENEEFTGQLKVAKDVEKLIGQVEIWEAEA-----KSVLDQDDVDTSMEE 768
Query: 359 VLTKLREDLELYYKKLLMQLEAREIKMRPKNLANITDSKNYLIIQITEVQHAIDQLKRKL 418
L L + + +L AR M ++ NI+ +++ + T +Q I + K K+
Sbjct: 769 SLKHL-----IAKGSMFDELMARSEDMLQMDIQNISSQESFQHVLTTGLQAKIQEAKEKV 823
Query: 419 DTDKMKLIVEVKMRKQAVSDLR-TLKTELAQKK 450
+ +KLI +K DL LK E +QK+
Sbjct: 824 QINVVKLIAALKNLTDVSPDLDIRLKMEESQKE 856
Score = 32.3 bits (72), Expect = 0.92
Identities = 39/179 (21%), Positives = 80/179 (44%), Gaps = 37/179 (20%)
Query: 286 ITDISLLQTEREKIIKQMKQVKEERRYLERNREELVKTVEKLFEQSKLKRYHAYNGWKKK 345
I + + L + +++Q+ +++EE ++L+ T ++ F H W K+
Sbjct: 2012 IMEATCLMDRYQTLLRQLSEIEEE--------DKLLPTEDQSFNDLAHDVIH----WIKE 2059
Query: 346 YLETKKVTAS------MEEVLTKLREDLELY------YKKLLMQLEAREIKMRPKNLANI 393
E+ V S +EE + K++E + L + ++ Q E+ E + K L +I
Sbjct: 2060 IKESLMVLNSSEGKMPLEERIQKIKEIILLKPEGDARIETIMKQAESSEAPLVQKTLTDI 2119
Query: 394 TDS-KNYLIIQITEVQHAIDQLKRKLDTDKMKLIVEVKMRKQAVSDLRTLKTELAQKKK 451
++ N L + T + H + KL++E + Q+ DLR + EL +K++
Sbjct: 2120 SNQWDNTLHLASTYLSH------------QEKLLLEGEKYLQSKEDLRLMLIELKKKQE 2166
Score = 31.6 bits (70), Expect = 1.6
Identities = 67/364 (18%), Positives = 158/364 (43%), Gaps = 69/364 (18%)
Query: 156 RQTNNGVNEADGTIHRPISV--TLFKEELGRDPSLLENTLKELPNKNQEEAGGKATAE-- 211
++ N ++ DGT+ + +++ ++ + ++++ +K L K ++ A+A+
Sbjct: 2293 QELENRLSLQDGTLKKILALAKSVKQNTSSVGQKIIKDDIKSLQCKQKDLENRLASAKQE 2352
Query: 212 ---------KSQIAKNQIGNSELPG-------SLEDSNNDCFGTKKSQCLWENEDDTAIS 255
KS+ + + G LPG +++S + +K + WE D+A+
Sbjct: 2353 MECCLNSILKSKRSTEKKGKFTLPGREKQATSDVQESTQESAAVEKLEEDWEINKDSAVE 2412
Query: 256 RRQDNQTA------------EKEYITLPDHPSLPCQPVLSSGITDISLLQTEREK---II 300
Q + E++ L + P + + + +I L T+ E I
Sbjct: 2413 MAMSKQLSLNAQESMKNTEDERKVNELQNQPLELDTMLRNEQLEEIEKLYTQLEAKKAAI 2472
Query: 301 KQMKQ------------VKEERRYLERNREELVKTVEKLFEQSKLKRYHAYNGWKKKYLE 348
K ++Q V Y ++ + L++ + L +++K +Y +++ YL
Sbjct: 2473 KPLEQTECLNKTETGALVLHNIGYSAQHLDNLLQALITL-KKNKESQYCVLRDFQE-YLA 2530
Query: 349 TKKVTASMEEVLTKLREDLEL----------YYKKLLMQLEARE-----IKMRPKNLAN- 392
V +SM+ +LT +E L++ KK + +E + +K++ +NL+N
Sbjct: 2531 A--VESSMKALLTD-KESLKVGPLDSVTYLDKIKKFIASIEKEKDSLGNLKIKWENLSNH 2587
Query: 393 ITD-SKNYLIIQITEVQHAIDQLKRKLDTDKMKLIVEVKMRKQAVSDLRTLKTELAQKKK 451
+TD K L QI +++H +Q+++++ + +VE ++ ++ + L Q+++
Sbjct: 2588 VTDMDKKLLESQIKQLEHGWEQVEQQIQKKYSQQVVEYDEFTTLMNKVQDTEISLQQQQQ 2647
Query: 452 IIHL 455
+ L
Sbjct: 2648 HLQL 2651
Score = 30.0 bits (66), Expect = 4.6
Identities = 29/110 (26%), Positives = 53/110 (48%), Gaps = 9/110 (8%)
Query: 297 EKIIKQMKQVKEERRYLERNREE-LVKTVEKLF-EQSKLKRYHAYNGWKKKYLETKKVTA 354
+ I+K KQ+ +E++ + R R + L+K E F E+ L + + + ++ E
Sbjct: 951 DNILKLEKQINKEKKLIRRGRTKGLIKEHEACFSEEGCLYQLNHHMEVLRELCEELPSQK 1010
Query: 355 SMEEVLTKLREDLELYYKKLLMQLEAREIKMRP------KNLANITDSKN 398
S +EV +L +D E ++LL + ++P KN IT S+N
Sbjct: 1011 SQQEV-KRLLKDYEQKIERLLKCASEIHMTLQPTAGGTSKNEGTITTSEN 1059
>gi|118918403 spectrin repeat containing, nuclear envelope 2 isoform
1 [Homo sapiens]
Length = 6885
Score = 42.0 bits (97), Expect = 0.001
Identities = 41/153 (26%), Positives = 69/153 (45%), Gaps = 16/153 (10%)
Query: 304 KQVKEERRYLERNRE-----ELVKTVEKLFEQSKLKRYHAYNGWKKKYLETKKVTASMEE 358
+ +K ++ + N E ++ K VEKL Q ++ A K L+ V SMEE
Sbjct: 714 QNIKAGEKHEKENEEFTGQLKVAKDVEKLIGQVEIWEAEA-----KSVLDQDDVDTSMEE 768
Query: 359 VLTKLREDLELYYKKLLMQLEAREIKMRPKNLANITDSKNYLIIQITEVQHAIDQLKRKL 418
L L + + +L AR M ++ NI+ +++ + T +Q I + K K+
Sbjct: 769 SLKHL-----IAKGSMFDELMARSEDMLQMDIQNISSQESFQHVLTTGLQAKIQEAKEKV 823
Query: 419 DTDKMKLIVEVKMRKQAVSDLR-TLKTELAQKK 450
+ +KLI +K DL LK E +QK+
Sbjct: 824 QINVVKLIAALKNLTDVSPDLDIRLKMEESQKE 856
Score = 32.3 bits (72), Expect = 0.92
Identities = 39/179 (21%), Positives = 80/179 (44%), Gaps = 37/179 (20%)
Query: 286 ITDISLLQTEREKIIKQMKQVKEERRYLERNREELVKTVEKLFEQSKLKRYHAYNGWKKK 345
I + + L + +++Q+ +++EE ++L+ T ++ F H W K+
Sbjct: 2012 IMEATCLMDRYQTLLRQLSEIEEE--------DKLLPTEDQSFNDLAHDVIH----WIKE 2059
Query: 346 YLETKKVTAS------MEEVLTKLREDLELY------YKKLLMQLEAREIKMRPKNLANI 393
E+ V S +EE + K++E + L + ++ Q E+ E + K L +I
Sbjct: 2060 IKESLMVLNSSEGKMPLEERIQKIKEIILLKPEGDARIETIMKQAESSEAPLVQKTLTDI 2119
Query: 394 TDS-KNYLIIQITEVQHAIDQLKRKLDTDKMKLIVEVKMRKQAVSDLRTLKTELAQKKK 451
++ N L + T + H + KL++E + Q+ DLR + EL +K++
Sbjct: 2120 SNQWDNTLHLASTYLSH------------QEKLLLEGEKYLQSKEDLRLMLIELKKKQE 2166
Score = 31.6 bits (70), Expect = 1.6
Identities = 67/364 (18%), Positives = 158/364 (43%), Gaps = 69/364 (18%)
Query: 156 RQTNNGVNEADGTIHRPISV--TLFKEELGRDPSLLENTLKELPNKNQEEAGGKATAE-- 211
++ N ++ DGT+ + +++ ++ + ++++ +K L K ++ A+A+
Sbjct: 2293 QELENRLSLQDGTLKKILALAKSVKQNTSSVGQKIIKDDIKSLQCKQKDLENRLASAKQE 2352
Query: 212 ---------KSQIAKNQIGNSELPG-------SLEDSNNDCFGTKKSQCLWENEDDTAIS 255
KS+ + + G LPG +++S + +K + WE D+A+
Sbjct: 2353 MECCLNSILKSKRSTEKKGKFTLPGREKQATSDVQESTQESAAVEKLEEDWEINKDSAVE 2412
Query: 256 RRQDNQTA------------EKEYITLPDHPSLPCQPVLSSGITDISLLQTEREK---II 300
Q + E++ L + P + + + +I L T+ E I
Sbjct: 2413 MAMSKQLSLNAQESMKNTEDERKVNELQNQPLELDTMLRNEQLEEIEKLYTQLEAKKAAI 2472
Query: 301 KQMKQ------------VKEERRYLERNREELVKTVEKLFEQSKLKRYHAYNGWKKKYLE 348
K ++Q V Y ++ + L++ + L +++K +Y +++ YL
Sbjct: 2473 KPLEQTECLNKTETGALVLHNIGYSAQHLDNLLQALITL-KKNKESQYCVLRDFQE-YLA 2530
Query: 349 TKKVTASMEEVLTKLREDLEL----------YYKKLLMQLEARE-----IKMRPKNLAN- 392
V +SM+ +LT +E L++ KK + +E + +K++ +NL+N
Sbjct: 2531 A--VESSMKALLTD-KESLKVGPLDSVTYLDKIKKFIASIEKEKDSLGNLKIKWENLSNH 2587
Query: 393 ITD-SKNYLIIQITEVQHAIDQLKRKLDTDKMKLIVEVKMRKQAVSDLRTLKTELAQKKK 451
+TD K L QI +++H +Q+++++ + +VE ++ ++ + L Q+++
Sbjct: 2588 VTDMDKKLLESQIKQLEHGWEQVEQQIQKKYSQQVVEYDEFTTLMNKVQDTEISLQQQQQ 2647
Query: 452 IIHL 455
+ L
Sbjct: 2648 HLQL 2651
Score = 30.0 bits (66), Expect = 4.6
Identities = 29/110 (26%), Positives = 53/110 (48%), Gaps = 9/110 (8%)
Query: 297 EKIIKQMKQVKEERRYLERNREE-LVKTVEKLF-EQSKLKRYHAYNGWKKKYLETKKVTA 354
+ I+K KQ+ +E++ + R R + L+K E F E+ L + + + ++ E
Sbjct: 951 DNILKLEKQINKEKKLIRRGRTKGLIKEHEACFSEEGCLYQLNHHMEVLRELCEELPSQK 1010
Query: 355 SMEEVLTKLREDLELYYKKLLMQLEAREIKMRP------KNLANITDSKN 398
S +EV +L +D E ++LL + ++P KN IT S+N
Sbjct: 1011 SQQEV-KRLLKDYEQKIERLLKCASEIHMTLQPTAGGTSKNEGTITTSEN 1059
>gi|5174457 kinetochore associated 2 [Homo sapiens]
Length = 642
Score = 42.0 bits (97), Expect = 0.001
Identities = 40/172 (23%), Positives = 79/172 (45%), Gaps = 24/172 (13%)
Query: 292 LQTEREKIIKQMKQVKEERRYLERNREELVKTVEKLFEQSKLKRYHAYNGWKKKYLETKK 351
L+ + + +Q+ ++++ER E L K L Q +++Y AY + +
Sbjct: 268 LEAKNRALNEQIARLEQEREKEPNRLESLRKLKASL--QGDVQKYQAYMSNLESH----- 320
Query: 352 VTASMEEVLTKLREDLELYYKKLLMQLEAREIKMRPKNLANITDSKNYLIIQI------- 404
+A +++ L L E++ ++LE IK L NI D++ Y + I
Sbjct: 321 -SAILDQKLNGLNEEIAR------VELECETIKQENTRLQNIIDNQKYSVADIERINHER 373
Query: 405 TEVQHAIDQLKRKLDTDKMKL---IVEVKMRKQAVSDLRTLKTELAQKKKII 453
E+Q I++L + L+ ++ KL ++ K+A+ +LA+K K+I
Sbjct: 374 NELQQTINKLTKDLEAEQQKLWNEELKYARGKEAIETQLAEYHKLARKLKLI 425
>gi|225579095 S-phase cyclin A-associated protein in the ER isoform
b [Homo sapiens]
Length = 1154
Score = 41.2 bits (95), Expect = 0.002
Identities = 64/299 (21%), Positives = 126/299 (42%), Gaps = 44/299 (14%)
Query: 185 DPSLLENTLKELPNKNQE----------EAGGKATAEKSQIAKNQIGNSELPGSLEDSNN 234
DPS + N++ E+ K +E EA A AE+ Q+ + ++E N+
Sbjct: 164 DPSDISNSMAEVLAKKEELADRLEKANEEAIASAIAEEEQLTREIEAEENNDINIETDND 223
Query: 235 DCFGTKKSQCL---------WEN---EDDTAISRRQDNQ---TAEKEYITLPDHPSLPCQ 279
F W + + + S RQ+ E+E P H +
Sbjct: 224 SDFSASMGSGSVSFCGMSMDWNDVLADYEARESWRQNTSWGDIVEEEPARPPGH-GIHMH 282
Query: 280 PVLSSGITDISLLQTEREKIIKQMKQVKEERRYLERNREELVKTVEKLFEQSKLKRYHAY 339
LSS ++ +++++ KQMK ++ E+ REE ++KL E+ K R
Sbjct: 283 EKLSSPSRKRTIAESKKKHEEKQMKA----QQLREKLREEKTLKLQKLLEREKDVRK--- 335
Query: 340 NGWKKKYLETKKVTASMEEVLTKLREDLELYYKKLLMQLEAREIKMRPKNLANITDSKNY 399
WK++ L+ ++ MEE L E+ + ++ + + E K+ N +++N
Sbjct: 336 --WKEELLDQRR--RMMEEKLLHAEFKREVQLQAIVKKAQEEEAKVNEIAFINTLEAQNK 391
Query: 400 ---LIIQITEVQHAIDQL---KRKLDTDKMKLIVEVKMRKQAVSDLRTLKT-ELAQKKK 451
++ ++ E + +++L +++ +K V+ RK+A+ R + EL K+K
Sbjct: 392 RHDVLSKLKEYEQRLNELQEERQRRQEEKQARDEAVQERKRALEAERQARVEELLMKRK 450
>gi|225579092 S-phase cyclin A-associated protein in the ER isoform
a [Homo sapiens]
Length = 1400
Score = 41.2 bits (95), Expect = 0.002
Identities = 64/299 (21%), Positives = 126/299 (42%), Gaps = 44/299 (14%)
Query: 185 DPSLLENTLKELPNKNQE----------EAGGKATAEKSQIAKNQIGNSELPGSLEDSNN 234
DPS + N++ E+ K +E EA A AE+ Q+ + ++E N+
Sbjct: 410 DPSDISNSMAEVLAKKEELADRLEKANEEAIASAIAEEEQLTREIEAEENNDINIETDND 469
Query: 235 DCFGTKKSQCL---------WEN---EDDTAISRRQDNQ---TAEKEYITLPDHPSLPCQ 279
F W + + + S RQ+ E+E P H +
Sbjct: 470 SDFSASMGSGSVSFCGMSMDWNDVLADYEARESWRQNTSWGDIVEEEPARPPGH-GIHMH 528
Query: 280 PVLSSGITDISLLQTEREKIIKQMKQVKEERRYLERNREELVKTVEKLFEQSKLKRYHAY 339
LSS ++ +++++ KQMK ++ E+ REE ++KL E+ K R
Sbjct: 529 EKLSSPSRKRTIAESKKKHEEKQMKA----QQLREKLREEKTLKLQKLLEREKDVRK--- 581
Query: 340 NGWKKKYLETKKVTASMEEVLTKLREDLELYYKKLLMQLEAREIKMRPKNLANITDSKNY 399
WK++ L+ ++ MEE L E+ + ++ + + E K+ N +++N
Sbjct: 582 --WKEELLDQRR--RMMEEKLLHAEFKREVQLQAIVKKAQEEEAKVNEIAFINTLEAQNK 637
Query: 400 ---LIIQITEVQHAIDQL---KRKLDTDKMKLIVEVKMRKQAVSDLRTLKT-ELAQKKK 451
++ ++ E + +++L +++ +K V+ RK+A+ R + EL K+K
Sbjct: 638 RHDVLSKLKEYEQRLNELQEERQRRQEEKQARDEAVQERKRALEAERQARVEELLMKRK 696
>gi|45935391 coiled-coil domain containing 69 [Homo sapiens]
Length = 296
Score = 41.2 bits (95), Expect = 0.002
Identities = 30/168 (17%), Positives = 77/168 (45%), Gaps = 13/168 (7%)
Query: 293 QTEREKIIKQMKQVKEERRYLERNREELVKTVEKLFEQSKLKRYHAYNGWKKKYLETKKV 352
Q E+E+ ++ ++ E++R LE EE ++ + +EQ K H++ ++
Sbjct: 77 QVEKERELELRDRLDEQQRVLEGKNEEALQVLRASYEQEKEALTHSF----------REA 126
Query: 353 TASMEEVLTKLREDLELYYKKLLMQLEAREIKMRPKNLANITDSKNYLIIQITEVQHAID 412
+++ +E + +L LE + K+ E+ + K++ + + ++ + I+
Sbjct: 127 SSTQQETIDRLTSQLEAFQAKMKRVEESILSRNYKKHIQDYGSPSQFWEQELESLHFVIE 186
Query: 413 QLKRKL-DTDKMKLIVEVKMRKQAVSDLRTLKTELAQKKKIIHLYNLN 459
++ + D+ +++E K + L T L Q+ + +H+ + N
Sbjct: 187 MKNERIHELDRRLILMETVKEKNLI--LEEKITTLQQENEDLHVRSRN 232
>gi|56961680 coiled-coil domain containing 147 [Homo sapiens]
Length = 872
Score = 41.2 bits (95), Expect = 0.002
Identities = 42/165 (25%), Positives = 78/165 (47%), Gaps = 24/165 (14%)
Query: 292 LQTEREKIIKQMKQV----KEERRYLERNREELVKTVEKLFEQSKLKRYHAYNGWKKKYL 347
+Q +++ KQ K + KE RY+ + +L + V E K++ ++ ++KK
Sbjct: 421 IQNYKDEAQKQRKIIFHLEKERDRYINQ-ASDLTQKVLMNMEDIKVRETQIFD-YRKKIA 478
Query: 348 ETKKVTASMEEVLTKLREDLELYYKKLLMQLEAREIKMRPKNLANITDSKNYLIIQITEV 407
E++ + + +R D LY K L+ EA++ ITD K L I I
Sbjct: 479 ESEIKLKQQQNLYEAVRSDRNLYSKNLV---EAQD---------EITDMKRKLKIMI--- 523
Query: 408 QHAIDQLKRKLDTDKMKLIVEVKMRKQAV-SDLRTLKTELAQKKK 451
H +D+LK + K +V++ + +Q + + TLK EL + ++
Sbjct: 524 -HQVDELKEDISA-KESALVKLHLEQQRIEKEKETLKAELQKLRQ 566
Score = 40.4 bits (93), Expect = 0.003
Identities = 35/173 (20%), Positives = 86/173 (49%), Gaps = 13/173 (7%)
Query: 292 LQTEREKIIKQMKQVKEERRYLERNREELVKTVEKLFEQSKLKRYHAYNGWKKK---YLE 348
L +E K+ + + Q E+++ ER++EE + + ++ + ++ A ++KK E
Sbjct: 165 LLSEVVKLRESLAQTTEQQQETERSKEEAEHAISQFQQEIQQRQNEASREFRKKEKLEKE 224
Query: 349 TKKVTASMEEVLTKLREDLELYYKKLLMQLEAREIKMRPKNLANITDSKNYLIIQITEV- 407
K++ A M+ T+++ L+ Y +K +L+ E +++ + + N +K Q+
Sbjct: 225 LKQIQADMDSRQTEIKA-LQQYVQKSKEELQKLEQQLKEQKILNERAAKELEQFQMRNAK 283
Query: 408 ------QHAIDQLKRKLDTDKMKLIVEVKMRKQAVSDLRTLKTELAQKKKIIH 454
QH++ + +L + + +E+K +++ V +R +L + ++ IH
Sbjct: 284 LQQENEQHSL--VCEQLSQENQQKALELKAKEEEVHQMRLDIGKLNKIREQIH 334
>gi|50083279 centrosome protein 4 [Homo sapiens]
Length = 1140
Score = 40.8 bits (94), Expect = 0.003
Identities = 32/164 (19%), Positives = 83/164 (50%), Gaps = 12/164 (7%)
Query: 287 TDISLLQTEREKIIKQMKQVKEERRYLERNREELVKTVEKLFEQSKLKRYHAYNGWKKKY 346
+++ L + EK+ +++ ++ + + LER++EE+++T +K ++K + K+K
Sbjct: 303 SEVVNLSNKNEKLCQELTEIDQLAQQLERHKEEVLETADKELGEAKKE-------IKRKL 355
Query: 347 LETKKVTASMEEVLTKLREDLELYYKKLLMQLEAREIKMRPKNLANITDSKNYLIIQITE 406
E + +EE + KL+ +L L K+ + +K + + + + + + + E
Sbjct: 356 SEMQ----DLEETMAKLQLELNLCQKEKERLSDELLVKSDLETVVHQLEQEKQRLSKKVE 411
Query: 407 VQHAIDQLKRKLDTDKMKLIVEVKMRKQAVSDLRTLKTELAQKK 450
A+ + + L+ ++M+L +K R ++ S L T + +++
Sbjct: 412 -SFAVTERQLTLEVERMRLEHGIKRRDRSPSRLDTFLKGIEEER 454
Score = 35.0 bits (79), Expect = 0.14
Identities = 28/158 (17%), Positives = 80/158 (50%), Gaps = 13/158 (8%)
Query: 289 ISLLQTEREKIIKQMKQVKEERRYLERNREELVKTVEKLFEQSKLKRYHAYNGWKKKYLE 348
+SL++ E+E + ++++ E+ L E + + LF +S+L++ + LE
Sbjct: 564 VSLMEKEKELALSDLRRIMAEKEALREKLEHIEEV--SLFGKSELEKTIEHLTCVNHQLE 621
Query: 349 TKKVTASMEEVLTKLREDLELYYKKLLMQLEAREIKMRPKNLANITDSKNYLIIQITEVQ 408
++K E+ +K+ L K+ + LE ++K++ + +++ ++ ++ ++
Sbjct: 622 SEKY-----ELKSKV-----LIMKETIESLE-NKLKVQAQKFSHVAGDSSHQKTEVNSLR 670
Query: 409 HAIDQLKRKLDTDKMKLIVEVKMRKQAVSDLRTLKTEL 446
+QL+R +D + +L ++ + A + ++ L+ ++
Sbjct: 671 IVNEQLQRSVDDYQHRLSIKRGELESAQAQIKILEEKI 708
>gi|41872583 Rho-associated, coiled-coil containing protein kinase 2
[Homo sapiens]
Length = 1388
Score = 40.4 bits (93), Expect = 0.003
Identities = 57/274 (20%), Positives = 120/274 (43%), Gaps = 18/274 (6%)
Query: 181 ELGRDPSLLENTLKELPNKNQEEAGGKATAEKS-QIAKNQIGNSELPGS-LEDSNNDCFG 238
EL + +L ++ L K ++E + + ++ Q+ ++ L+ NN
Sbjct: 777 ELLKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLME 836
Query: 239 TKKSQCLWENEDDTAISRRQDNQTAEKEYITLPDHPSLPCQPVLSSGI-TDISLLQTERE 297
K N + R++ Q A+ + L D L + S+ T + L+ E E
Sbjct: 837 MKM------NLEKQNAELRKERQDADGQMKELQDQ--LEAEQYFSTLYKTQVRELKEECE 888
Query: 298 KIIKQMKQVKEERRYLERNREELVKTVEKLFEQSKLKRYHAYNGWKKKY--LETKKVTAS 355
+ K K+++++++ L+ R+ L +E ++ ++ A + +++Y LE +K+
Sbjct: 889 EKTKLGKELQQKKQELQDERDSLAAQLEITLTKADSEQL-ARSIAEEQYSDLEKEKIMKE 947
Query: 356 MEEVLTKLREDLELYYKKLLMQLEAREIKMRPKNLANITDSKNYLIIQITEVQHAIDQLK 415
+E R EL K + + ++AN+ + K L ++ +VQ +QL
Sbjct: 948 LEIKEMMARHKQELTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQ---EQLS 1004
Query: 416 RKLDTDKMKLIVEVKMRKQAVSDLRTLKTELAQK 449
R D + ++ + KQ +++ RTLKT+ K
Sbjct: 1005 RLKDEEISAAAIKAQFEKQLLTE-RTLKTQAVNK 1037
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 40.4 bits (93), Expect = 0.003
Identities = 55/264 (20%), Positives = 119/264 (45%), Gaps = 34/264 (12%)
Query: 189 LENTLKELPNKNQEEAGGKATAEKSQIAKNQIGNSELPGSLEDSNNDCFGTKKSQCLWEN 248
LE L +L ++ +EE E++QI +N+ ++ ++D + ++ +
Sbjct: 920 LEEILHDLESRVEEEE------ERNQILQNE--KKKMQAHIQDLEEQLDEEEGARQKLQL 971
Query: 249 EDDTAISRRQDNQTAEKEYITLPDHPS--LPCQPVLSSGITDISLLQTEREKIIKQMKQV 306
E TA ++ + E+E + L D S + + ++ I + S E E+ K + ++
Sbjct: 972 EKVTAEAKIKK---MEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKI 1028
Query: 307 KEERRYLERNREELVKTVEKLFEQ-SKLKRYHAYNGWKKKYLETKKVTASMEEVLTKLRE 365
+ ++ + + EE +K EK ++ K KR + T +++ + +L+
Sbjct: 1029 RNKQEVMISDLEERLKKEEKTRQELEKAKR------------KLDGETTDLQDQIAELQA 1076
Query: 366 DLELYYKKLLMQLEAREIKMRPKNLANITDS---KNYLIIQITEVQHAIDQLKRKLDTDK 422
++ +L +QL +E +++ LA D KN + + E+Q I +L+ +++K
Sbjct: 1077 QID----ELKLQLAKKEEELQGA-LARGDDETLHKNNALKVVRELQAQIAELQEDFESEK 1131
Query: 423 MKLIVEVKMRKQAVSDLRTLKTEL 446
K ++ +L LKTEL
Sbjct: 1132 ASRNKAEKQKRDLSEELEALKTEL 1155
Score = 39.7 bits (91), Expect = 0.006
Identities = 58/297 (19%), Positives = 121/297 (40%), Gaps = 43/297 (14%)
Query: 179 KEELGRDPSLLENTLKELPNKNQEEAGGKATAEKSQIAKNQIGNSELPGSLEDSNNDCFG 238
KEE R L +++L + + EKS+ A Q E+ LE+ ++
Sbjct: 1499 KEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQ-QVEEMRTQLEELEDELQA 1557
Query: 239 TKKSQCLWENEDDTAISR------RQDNQTAEKEYITLPDHPSLPCQ----------PVL 282
T+ ++ E ++ +D Q EK+ + + L + V
Sbjct: 1558 TEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVA 1617
Query: 283 SSGITDISLLQTE---------REKIIKQMKQVKEERRYLERNREELVKTVEKLFEQSKL 333
S +I L E R+++IKQ+++++ + + +R EE + +++F QSK
Sbjct: 1618 SKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSK- 1676
Query: 334 KRYHAYNGWKKKYLETKKVTASMEEVLTKLREDLELYYKKLLMQLEAREIKMRPKNLANI 393
E++K S+E + +L+E EL + + +E + N
Sbjct: 1677 --------------ESEKKLKSLEAEILQLQE--ELASSERARRHAEQERDELADEITNS 1720
Query: 394 TDSKNYLIIQITEVQHAIDQLKRKLDTDKMKLIVEVKMRKQAVSDLRTLKTELAQKK 450
K+ L+ + ++ I QL+ +L+ ++ + + ++ + TL ELA ++
Sbjct: 1721 ASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAER 1777
Score = 35.8 bits (81), Expect = 0.083
Identities = 51/267 (19%), Positives = 108/267 (40%), Gaps = 50/267 (18%)
Query: 190 ENTLKELPNKNQEEAGGKATAEKSQIAKNQIGNSELPGSLEDSNNDCFGTKKSQCLWENE 249
E T +EL K + + G+ T + QIA+ Q EL K Q + E
Sbjct: 1047 EKTRQEL-EKAKRKLDGETTDLQDQIAELQAQIDEL---------------KLQLAKKEE 1090
Query: 250 DDTAISRRQDNQTAEKEYITLPDHPSLPCQPVLSSGITDISLLQTEREKIIKQMKQVKEE 309
+ R D++T K ++ + + LQ + ++ + + K
Sbjct: 1091 ELQGALARGDDETLHK-----------------NNALKVVRELQAQIAELQEDFESEKAS 1133
Query: 310 RRYLERNREELVKTVEKLFEQSKLKRYHAYNGWKKKYLETKKVTASMEEVLTKLREDLEL 369
R E+ + +L + +E L K + +T TA+ +E+ TK +++
Sbjct: 1134 RNKAEKQKRDLSEELEAL---------------KTELEDTLDTTAAQQELRTKREQEVAE 1178
Query: 370 YYKKLLMQLEAREIKMRPKNLANIT--DSKNYLIIQITEVQHAIDQLKRKLDTDKMKLIV 427
K L + + E +++ + T + + + Q + +++ K+ L+TD +L
Sbjct: 1179 LKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELAC 1238
Query: 428 EVKMRKQAVSDLRTLKTELAQKKKIIH 454
EVK+ +Q ++ + +L + + +H
Sbjct: 1239 EVKVLQQVKAESEHKRKKLDAQVQELH 1265
Score = 33.1 bits (74), Expect = 0.54
Identities = 35/168 (20%), Positives = 85/168 (50%), Gaps = 23/168 (13%)
Query: 292 LQTEREKIIKQMKQVKEERRYLERNREELVKTVEKLFEQSKLKRYHAYNGWKKKYLETKK 351
LQ + E+++K VKE++ +E EE+ + ++L E+ + ++ ET +
Sbjct: 854 LQAKDEELLK----VKEKQTKVEGELEEMERKHQQLLEEKNILA-------EQLQAET-E 901
Query: 352 VTASMEEVLTKL---REDLELYYKKLLMQLEAREIKMRPKNLANITDSKNYLIIQITEVQ 408
+ A EE+ +L +++LE ++L LE+R + +N + + K + I +++
Sbjct: 902 LFAEAEEMRARLAAKKQELE----EILHDLESRVEEEEERNQI-LQNEKKKMQAHIQDLE 956
Query: 409 HAIDQ---LKRKLDTDKMKLIVEVKMRKQAVSDLRTLKTELAQKKKII 453
+D+ ++KL +K+ ++K ++ + L ++ ++KK++
Sbjct: 957 EQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLM 1004
Score = 33.1 bits (74), Expect = 0.54
Identities = 60/316 (18%), Positives = 128/316 (40%), Gaps = 37/316 (11%)
Query: 166 DGTIHRPISVTLFKEELGRDPSLLENTLKELPNKNQEEAGGKATAEKSQIAKNQIGNS-- 223
D T+H+ ++ + +E + L E+ E ++N+ E + +E+ + K ++ ++
Sbjct: 1101 DETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLD 1160
Query: 224 -----------------ELPGSLEDSNNDC------FGTKKSQCLWENEDDTAISRRQDN 260
EL +LE+ + + + L E + ++R
Sbjct: 1161 TTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKA 1220
Query: 261 QTAEKEYITLPDHPSLPCQPVLSSGITDISLLQTEREKIIKQMKQVKEERRYLERNREEL 320
+ + D+ L C+ + + S + +R+K+ Q++++ + +R R EL
Sbjct: 1221 NLEKNKQGLETDNKELACEVKVLQQVKAES--EHKRKKLDAQVQELHAKVSEGDRLRVEL 1278
Query: 321 VKTVEKLFEQSKLKRYHAY-NGWKKKYLETKKVTASMEEVLTKLREDLE------LYYKK 373
+ KL Q++L +KK ++ K AS+E L +E L+ L
Sbjct: 1279 AEKASKL--QNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSS 1336
Query: 374 LLMQLEAREIKMRPKNLANITDSKNYLIIQITEVQHAIDQLKRKLDTDKMKLIVEVKMRK 433
+ QLE + ++ + KN L Q+ +Q + K+K+D D + + +K
Sbjct: 1337 RIRQLEEEKNSLQEQQEEEEEARKN-LEKQVLALQSQLADTKKKVDDDLGTIESLEEAKK 1395
Query: 434 QAVSDLRTLKTELAQK 449
+ + D L L +K
Sbjct: 1396 KLLKDAEALSQRLEEK 1411
Score = 30.4 bits (67), Expect = 3.5
Identities = 36/135 (26%), Positives = 62/135 (45%), Gaps = 12/135 (8%)
Query: 291 LLQTE-REKI--IKQMKQVKEERRYLERNREELVKTVEKLFEQSKLKRYHAYNGWKKKYL 347
LLQ E R+K+ +++Q++EE+ L+ +EE + K E+ L KKK
Sbjct: 1323 LLQEETRQKLNLSSRIRQLEEEKNSLQEQQEE-EEEARKNLEKQVLALQSQLADTKKKVD 1381
Query: 348 ETKKVTASMEEVLTKLREDLELYYKKLLMQLEAREIKMRPKN-----LANIT---DSKNY 399
+ S+EE KL +D E ++L + A + + KN L ++T D +
Sbjct: 1382 DDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQ 1441
Query: 400 LIIQITEVQHAIDQL 414
+ + + Q DQL
Sbjct: 1442 VASNLEKKQKKFDQL 1456
>gi|115511012 coiled-coil domain containing 136 [Homo sapiens]
Length = 1154
Score = 40.4 bits (93), Expect = 0.003
Identities = 36/169 (21%), Positives = 80/169 (47%), Gaps = 18/169 (10%)
Query: 295 EREKIIKQMKQVKEERRYLERNREELVKTVEKLFEQSK--LKRYHAYNGWKKKYLETKKV 352
E+EK++++ +Q++EE + E + L TV E ++ + + K+ Y +K
Sbjct: 435 EKEKLLERQQQLQEELQCHEAELQHLRDTVASFKESNEKDTETHAQLQEMKQLYQASKDE 494
Query: 353 TASMEEVLTKLREDLELYYKKLLMQLEAREIKMR---PKNLANITDSKNYLIIQITEVQH 409
+ + +L +DL LL QLE +E+K P++ + + L+ ++TE+Q
Sbjct: 495 LERQKHMYDQLEQDL------LLCQLELKELKASHPIPEDKGKCANKCDTLLSRLTELQE 548
Query: 410 AIDQLKRKLDTDKMKLIVEVKMRKQAVSDLRTLKTELAQKKKIIHLYNL 458
++++ +M+ + + + D R ++ E Q ++ +H L
Sbjct: 549 KYKASQKEMGQLQME-------QCELLEDQRRMQEEQGQLQEELHRLTL 590
Score = 30.4 bits (67), Expect = 3.5
Identities = 47/182 (25%), Positives = 84/182 (46%), Gaps = 28/182 (15%)
Query: 290 SLLQTEREKIIKQMKQVKEERRYLERNREELVKTVEKLFEQSKLKRYHAYNGWKKKYLET 349
S LQ + EK++ + K +KEE ER +E ++ +EK K + K L+T
Sbjct: 875 SQLQEQMEKLLAKQKDLKEELDACEREFKECMECLEKPMAPQNDKN-------EIKELQT 927
Query: 350 K------KVTASMEE------VLTKLREDLELYYKKLLMQLEAREI---KMRPKNLANIT 394
K + ASM+E V +L L+ ++L E R + R KN AN
Sbjct: 928 KLRELQLQYQASMDEQGRLLVVQEQLEGQLQCCQEELRQLREKRPSVVKEARGKN-ANKN 986
Query: 395 DSKNYLIIQITEV-QHAIDQLKRKLDTDK-MKLIVEVKMRKQAVSDL---RTLKTELAQK 449
+KN +++ +V + D + L+T K +++++ K ++ + L K E+ ++
Sbjct: 987 MNKNANGVKMKKVTKPCSDTSESDLETRKSLEVVLYYKASQRKLDGLAKEEEKKEEMEEE 1046
Query: 450 KK 451
KK
Sbjct: 1047 KK 1048
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 40.0 bits (92), Expect = 0.004
Identities = 31/110 (28%), Positives = 54/110 (49%), Gaps = 12/110 (10%)
Query: 345 KYLETKKVTASMEEVLTKLREDLELYYKKLLMQLEAREIKMRPKNLANITDSKNYLIIQI 404
K E +K ASM+E T+L+E LE + EAR ++ K + ++ KN L +Q+
Sbjct: 841 KSAEREKEMASMKEEFTRLKEALE--------KSEARRKELEEK-MVSLLQEKNDLQLQV 891
Query: 405 TEVQHAIDQLKRKLD---TDKMKLIVEVKMRKQAVSDLRTLKTELAQKKK 451
Q + + + D +K++L +VK + + D + EL KK+
Sbjct: 892 QAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKR 941
Score = 32.7 bits (73), Expect = 0.71
Identities = 56/284 (19%), Positives = 117/284 (41%), Gaps = 52/284 (18%)
Query: 180 EELGRDPSLLENTLKELPNK--NQEEAGGKATAEKSQIAKNQIGNSELPGSLEDSNNDCF 237
++L ++ LE +KE+ + ++EE + TA+K ++ SEL ++D
Sbjct: 906 DQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDEC---SELKRDIDDLELTLA 962
Query: 238 GTKKSQCLWENEDDTAISRRQDNQTAEKEYITLPDHPSLPCQPVLSSGITDISLLQTERE 297
+K + EN + N T E +G+ +I T+ +
Sbjct: 963 KVEKEKHATEN--------KVKNLTEEM------------------AGLDEIIAKLTKEK 996
Query: 298 KIIKQMKQVKEERRYLERNREELVKTVEKLFEQSKLKRYHAYNGWKKKYLETKKVTASME 357
K +++ Q + E E+ V T+ K +K+K + + + KKV +E
Sbjct: 997 KALQEAHQQALDDLQAE---EDKVNTLTK----AKVKLEQQVDDLEGSLEQEKKVRMDLE 1049
Query: 358 EVLTKLREDLELYYKKLL----------MQLEAREIKMRPKNLANITDSK---NYLIIQI 404
KL DL+L + ++ +L+ ++ ++ N A I D + + L ++
Sbjct: 1050 RAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALN-ARIEDEQALGSQLQKKL 1108
Query: 405 TEVQHAIDQLKRKLDTDKMKLIVEVKMRKQAVSDLRTLKTELAQ 448
E+Q I++L+ +L+ ++ K+R +L + L +
Sbjct: 1109 KELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEE 1152
Score = 32.3 bits (72), Expect = 0.92
Identities = 42/188 (22%), Positives = 82/188 (43%), Gaps = 36/188 (19%)
Query: 288 DISLLQTEREKIIKQMKQVKEERR---------------------YLERNREELVKTVEK 326
D+S LQTE E+ +++ + +E+ + +LER ++ + +T++
Sbjct: 1733 DLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKD 1792
Query: 327 LFEQSKLKRYHAYNGWKKKYLETKKVTASMEEVLTKLREDLELYYKKLLMQLEA-REIKM 385
L + A G KK + +K+ A + E L +LE K+ ++ R+ +
Sbjct: 1793 LQHRLDEAEQIALKGGKK---QLQKLEARVRE----LENELEAEQKRNAESVKGMRKSER 1845
Query: 386 RPKNLANIT--DSKNYLIIQITEVQHAIDQLKRKLDTDKMKLIVEVKMRKQAVSDLRTLK 443
R K L T D KN L +Q +D+L+ K+ K + + +S R ++
Sbjct: 1846 RIKELTYQTEEDRKNLL-----RLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQ 1900
Query: 444 TELAQKKK 451
EL + ++
Sbjct: 1901 HELDEAEE 1908
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 40.0 bits (92), Expect = 0.004
Identities = 40/180 (22%), Positives = 85/180 (47%), Gaps = 16/180 (8%)
Query: 292 LQTEREKIIKQMKQVKEERRYLERNREELVKTVEKLFEQSKLKRYHAYNGWKKKYLETKK 351
L+ E+ ++ ++K+ + E ++ REE E Q +L+ + L+T+K
Sbjct: 880 LEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQK 939
Query: 352 VTASMEEVLTKLREDLELYYKK-------LLMQLE--AREIKMRPK----NLANITDSKN 398
A + L +LR+D+++ K L QL+ RE+K + +LA + + +
Sbjct: 940 ELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESS 999
Query: 399 YLIIQITEVQHAIDQLKRKL--DTDKMKLI-VEVKMRKQAVSDLRTLKTELAQKKKIIHL 455
L+ ++Q ++ LK +L D +L+ EV+ + + + ++ EL ++K + L
Sbjct: 1000 SLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTL 1059
Score = 32.7 bits (73), Expect = 0.71
Identities = 47/210 (22%), Positives = 102/210 (48%), Gaps = 25/210 (11%)
Query: 246 WENEDDTAISRRQDNQTAEKEYITLPDHPSLPCQPVLSSGITDISLLQTEREKIIKQMKQ 305
WE E+ A+ +R T E++ + ++ Q + S + LLQ RE++ +Q++
Sbjct: 426 WE-EEGKALRQRLQKLTGERDTLA---GQTVDLQGEVDSLSKERELLQKAREELRQQLEV 481
Query: 306 VKEERRYLERNREELVKTVEKLFEQSKLKRYHAYNGWKKKY--------LETKKVTASME 357
+++E L R EL + Q + ++ + +++ LE K+ + S+
Sbjct: 482 LEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQ-SESLS 540
Query: 358 EVLTKLREDLE-LYYKKLLMQLEAREI----KMRPKNLANITDSKNYLIIQITEVQHA-- 410
E++T LRE LE + + L++ E E+ +++A ++ S+N L ++ +++ A
Sbjct: 541 ELIT-LREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAV 599
Query: 411 -IDQLKRKLDTDKMKL---IVEVKMRKQAV 436
+ L L DK+ L +++++ Q+V
Sbjct: 600 KLSALNEALALDKVGLNQQLLQLEEENQSV 629
Score = 30.0 bits (66), Expect = 4.6
Identities = 37/151 (24%), Positives = 77/151 (50%), Gaps = 20/151 (13%)
Query: 302 QMKQVKEERRYLERNREELVKTVEKLFEQS-KLKRYHAYNGWKKKYLETKKVTASMEEVL 360
++ + +ER L++ REEL + +E L +++ +L+R + + + +K EE+
Sbjct: 457 EVDSLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQK-EEQQEELH 515
Query: 361 TKLREDLELYYKKLLMQLEAREIKMRPKNLANITDSKNYLIIQITEVQHAIDQLKRKLDT 420
+RE L +++LM LEA++ ++L+ + + L E H +L R+ T
Sbjct: 516 LAVRERERL--QEMLMGLEAKQ----SESLSELITLREAL-----ESSHLEGELLRQEQT 564
Query: 421 DKMKLIVEVKMRKQAVSDL----RTLKTELA 447
+ + + +Q++++L TLKTE+A
Sbjct: 565 E---VTAALARAEQSIAELSSSENTLKTEVA 592
Score = 30.0 bits (66), Expect = 4.6
Identities = 39/166 (23%), Positives = 76/166 (45%), Gaps = 37/166 (22%)
Query: 292 LQTEREKIIKQMKQVKEERRYLERNREELVKTVEKL--FEQSKLKRYHAYNGWKKKYLET 349
++++RE+I + +Q + + LER +EL+ E++ E + + +T
Sbjct: 1632 VKSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTR-------------QT 1678
Query: 350 KKVTASMEEVLTKLRE-DLELYYKKLLMQLEAREIKMRPKNLANITDSKNYLIIQITEVQ 408
K + +E++ LRE EL ++ LMQ A E K K Q ++
Sbjct: 1679 KILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSK-------------AQRGSLE 1725
Query: 409 HAIDQLKRKLDTDKMKLIVEVKMRKQAVSDLRTLKTELAQKKKIIH 454
H + + DK K EV+ +++ + +L+ LK +L Q+ + +H
Sbjct: 1726 H-----MKLILRDKEK---EVECQQEHIHELQELKDQLEQQLQGLH 1763
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 40.0 bits (92), Expect = 0.004
Identities = 33/156 (21%), Positives = 78/156 (50%), Gaps = 14/156 (8%)
Query: 295 EREKIIKQMKQVKEERRYLERNREELVKTVEKLFEQSKLKRYHAYNGWKKKYLETKKVTA 354
E EK + ++ +E RR L+ +E +KT+EK E+ ++ + K++ ++ K
Sbjct: 415 ELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMK--K 472
Query: 355 SMEEVLTKLREDLELYYKKLLMQLEAREIKMRPKNLANITDSKNYLIIQITEVQHAIDQL 414
S EE + KL+ +L+ K +L +E ++ K + + + + + + Q ++
Sbjct: 473 SSEEQIAKLQ---KLHEK----ELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKI 525
Query: 415 KRKLDTDKMKLIVEVKMRKQAV-----SDLRTLKTE 445
++ + + + E++++K+A+ + LR L+ E
Sbjct: 526 SQEKEQQESLALEELELQKKAILTESENKLRDLQQE 561
Score = 39.7 bits (91), Expect = 0.006
Identities = 44/181 (24%), Positives = 83/181 (45%), Gaps = 35/181 (19%)
Query: 292 LQTEREKIIKQMKQVKEERR------------------YLERNREELVKTVEKLFE--QS 331
L+TER + KQ+ +V+ +++ LE+ E+ + V+ L + +S
Sbjct: 831 LETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYES 890
Query: 332 KLKRYHAYNGWKKKYLETKKVTASMEEVLTKLREDLELYYKKLLMQLEAREIKMRPKNLA 391
KL+ K+ +TK++ E ++ ++RE + + L +L A+E + N
Sbjct: 891 KLE------DGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEE 944
Query: 392 NITDSKNYLIIQITEVQHAIDQLKRKLDTDKMKLI-VEVKMRKQAVSDLRTLKTELAQKK 450
T KN Q +++ + K +T K KL+ E K++K +L EL+QK+
Sbjct: 945 YETKFKN----QEKKMEKVKQKAKEMQETLKKKLLDQEAKLKK----ELENTALELSQKE 996
Query: 451 K 451
K
Sbjct: 997 K 997
Score = 36.2 bits (82), Expect = 0.064
Identities = 57/255 (22%), Positives = 110/255 (43%), Gaps = 27/255 (10%)
Query: 194 KELPNKNQEEAGGKATAEKSQIAKNQIGNSELPGSLEDSNNDCFGTKKSQCLWENEDDTA 253
KEL K QE T E+ ++ +LE S ++ + + E ++ A
Sbjct: 487 KELARKEQELTKKLQTREREF-------QEQMKVALEKSQSEYLKISQEK---EQQESLA 536
Query: 254 ISRRQDNQTAEKEYITLPDHPSLPCQPVLSSGITDISLLQTEREKIIKQMK-QVKEERRY 312
+ ++ + +K +T ++ Q + T I L++ EK +++ K Q K+ +
Sbjct: 537 L---EELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVH 593
Query: 313 LE----RNREELVKTVEKLFEQSKLKRYHAYNGWKKKYLETKK-VTASMEEVLTKLREDL 367
LE ++ +E+ VEK + + ++ W +K K+ ME++ K ++
Sbjct: 594 LEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEK 653
Query: 368 ELYYKKLLMQLEAREIKMRPKNLANITDSKNYL---IIQITEVQHAIDQLKRKLD----- 419
E K + +A +M K L + + L +++EV A +L+ +L
Sbjct: 654 ETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQ 713
Query: 420 TDKMKLIVEVKMRKQ 434
TDKMK +E KM +Q
Sbjct: 714 TDKMKQELEAKMDEQ 728
Score = 33.1 bits (74), Expect = 0.54
Identities = 31/124 (25%), Positives = 59/124 (47%), Gaps = 14/124 (11%)
Query: 296 REKIIKQMKQVKEERRYLERNREELVKTVEKLFEQSKLKRYHAYNGWKKKYLETKKVTAS 355
+E++++ +E++R + +L KT ++ F+ K + + K LE KK++
Sbjct: 1154 QEQLVELKMLAEEDKRKVSELTSKL-KTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLS-- 1210
Query: 356 MEEVLTKLREDLELYYKKLLMQLEAREIKMRPKNLANITDSK-NYLIIQITEVQHAIDQL 414
+L L++ KK LEA + L NI+ SK N ++ +I+ QH ++
Sbjct: 1211 -----EELAIQLDICCKKTEALLEA-----KTNELINISSSKTNAILSRISHCQHRTTKV 1260
Query: 415 KRKL 418
K L
Sbjct: 1261 KEAL 1264
Score = 31.2 bits (69), Expect = 2.1
Identities = 67/313 (21%), Positives = 123/313 (39%), Gaps = 63/313 (20%)
Query: 185 DPSLLENTLKELPNKNQ----------EEAGGKATAEKSQIAKNQIGNSELPGSLEDSNN 234
D S++ + +EL KN+ E+ GGK + Q +N ++ +L++
Sbjct: 1790 DQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVF--DDVQKTLQEKEL 1847
Query: 235 DCFGTKKSQCLWEN--EDDTAISRRQDNQTAEKEYITLP----------DHPSLPCQPVL 282
C Q L + E D+ + R+++ E E +T D + P + +L
Sbjct: 1848 TC------QILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTE-LL 1900
Query: 283 SSGITDISLLQTEREKIIKQMKQVKEERRY----LERNREELVKTVEKLFEQSKLKRYHA 338
+ S + K++ M+ + + ER +++L K + +L Q L+
Sbjct: 1901 EENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRL--QKDLRMLRK 1958
Query: 339 YNGWKKKYLETKKVTASMEEVLTKLREDLELYYKKLLMQL----------EAREIKMRPK 388
+ + + L+ K+ EE + + +EDLEL + L QL + +E++M K
Sbjct: 1959 EHQQELEILK-KEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIK 2017
Query: 389 NLANIT------------DSKNYLIIQITEVQHAIDQLKRKLDTDKMKLIVEVKMRKQAV 436
N + N L+ +I E D LKR + L + V
Sbjct: 2018 ETINKAQEVEAELLESHQEETNQLLKKIAEKD---DDLKRTAKRYEEILDAREEEMTAKV 2074
Query: 437 SDLRTLKTELAQK 449
DL+T EL +K
Sbjct: 2075 RDLQTQLEELQKK 2087
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.131 0.361
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,216,300
Number of Sequences: 37866
Number of extensions: 731219
Number of successful extensions: 3832
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 43
Number of HSP's successfully gapped in prelim test: 363
Number of HSP's that attempted gapping in prelim test: 3104
Number of HSP's gapped (non-prelim): 957
length of query: 459
length of database: 18,247,518
effective HSP length: 106
effective length of query: 353
effective length of database: 14,233,722
effective search space: 5024503866
effective search space used: 5024503866
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.