Guide to the Human Genome
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Search of human proteins with 32401435

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|32401435 G protein-coupled receptor 141 [Homo sapiens]
         (305 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|32401435 G protein-coupled receptor 141 [Homo sapiens]             617   e-177
gi|5729798 cysteinyl leukotriene receptor 1 [Homo sapiens]             92   4e-19
gi|148225857 G protein-coupled receptor 34 [Homo sapiens]              87   1e-17
gi|4885319 G protein-coupled receptor 34 [Homo sapiens]                87   1e-17
gi|224586796 G protein-coupled receptor 87 [Homo sapiens]              86   3e-17
gi|148235349 G protein-coupled receptor 18 [Homo sapiens]              83   3e-16
gi|15029528 G protein-coupled receptor 18 [Homo sapiens]               83   3e-16
gi|9966851 cysteinyl leukotriene receptor 2 [Homo sapiens]             82   8e-16
gi|241982708 G-protein coupled purinergic receptor P2Y5 [Homo sa...    80   2e-15
gi|241982706 G-protein coupled purinergic receptor P2Y5 [Homo sa...    80   2e-15
gi|33695113 G-protein coupled purinergic receptor P2Y5 [Homo sap...    80   2e-15
gi|125625354 P2Y14 receptor [Homo sapiens]                             79   7e-15
gi|125625352 P2Y14 receptor [Homo sapiens]                             79   7e-15
gi|52426789 oxoglutarate (alpha-ketoglutarate) receptor 1 [Homo ...    78   1e-14
gi|4557857 somatostatin receptor 1 [Homo sapiens]                      77   1e-14
gi|238814307 G protein-coupled receptor 17 isoform b [Homo sapiens]    77   2e-14
gi|238814305 G protein-coupled receptor 17 isoform b [Homo sapiens]    77   2e-14
gi|4885301 G protein-coupled receptor 17 isoform a [Homo sapiens]      77   2e-14
gi|238814302 G protein-coupled receptor 17 isoform a [Homo sapiens]    77   2e-14
gi|14211849 putative purinergic receptor FKSG79 [Homo sapiens]         77   2e-14
gi|53828924 G protein-coupled receptor 7 [Homo sapiens]                76   4e-14
gi|4557859 somatostatin receptor 2 [Homo sapiens]                      75   6e-14
gi|39725940 opioid receptor, kappa 1 [Homo sapiens]                    74   2e-13
gi|153792776 G protein-coupled receptor 171 [Homo sapiens]             74   2e-13
gi|4885311 lysophosphatidic acid receptor 4 [Homo sapiens]             73   3e-13
gi|30581170 CC chemokine receptor 3 [Homo sapiens]                     73   4e-13
gi|4502637 CC chemokine receptor 3 [Homo sapiens]                      73   4e-13
gi|31881792 leukotriene B4 receptor [Homo sapiens]                     72   5e-13
gi|221218998 leukotriene B4 receptor [Homo sapiens]                    72   5e-13
gi|4502631 chemokine (C-C motif) receptor 1 [Homo sapiens]             71   1e-12

>gi|32401435 G protein-coupled receptor 141 [Homo sapiens]
          Length = 305

 Score =  617 bits (1592), Expect = e-177
 Identities = 305/305 (100%), Positives = 305/305 (100%)

Query: 1   MPGHNTSRNSSCDPIVTPHLISLYFIVLIGGLVGVISILFLLVKMNTRSVTTMAVINLVV 60
           MPGHNTSRNSSCDPIVTPHLISLYFIVLIGGLVGVISILFLLVKMNTRSVTTMAVINLVV
Sbjct: 1   MPGHNTSRNSSCDPIVTPHLISLYFIVLIGGLVGVISILFLLVKMNTRSVTTMAVINLVV 60

Query: 61  VHSVFLLTVPFRLTYLIKKTWMFGLPFCKFVSAMLHIHMYLTFLFYVVILVTRYLIFFKC 120
           VHSVFLLTVPFRLTYLIKKTWMFGLPFCKFVSAMLHIHMYLTFLFYVVILVTRYLIFFKC
Sbjct: 61  VHSVFLLTVPFRLTYLIKKTWMFGLPFCKFVSAMLHIHMYLTFLFYVVILVTRYLIFFKC 120

Query: 121 KDKVEFYRKLHAVAASAGMWTLVIVIVVPLVVSRYGIHEEYNEEHCFKFHKELAYTYVKI 180
           KDKVEFYRKLHAVAASAGMWTLVIVIVVPLVVSRYGIHEEYNEEHCFKFHKELAYTYVKI
Sbjct: 121 KDKVEFYRKLHAVAASAGMWTLVIVIVVPLVVSRYGIHEEYNEEHCFKFHKELAYTYVKI 180

Query: 181 INYMIVIFVIAVAVILLVFQVFIIMLMVQKLRHSLLSHQEFWAQLKNLFFIGVILVCFLP 240
           INYMIVIFVIAVAVILLVFQVFIIMLMVQKLRHSLLSHQEFWAQLKNLFFIGVILVCFLP
Sbjct: 181 INYMIVIFVIAVAVILLVFQVFIIMLMVQKLRHSLLSHQEFWAQLKNLFFIGVILVCFLP 240

Query: 241 YQFFRIYYLNVVTHSNACNSKVAFYNEIFLSVTAISCYDLLLFVFGGSHWFKQKIIGLWN 300
           YQFFRIYYLNVVTHSNACNSKVAFYNEIFLSVTAISCYDLLLFVFGGSHWFKQKIIGLWN
Sbjct: 241 YQFFRIYYLNVVTHSNACNSKVAFYNEIFLSVTAISCYDLLLFVFGGSHWFKQKIIGLWN 300

Query: 301 CVLCR 305
           CVLCR
Sbjct: 301 CVLCR 305


>gi|5729798 cysteinyl leukotriene receptor 1 [Homo sapiens]
          Length = 337

 Score = 92.4 bits (228), Expect = 4e-19
 Identities = 62/281 (22%), Positives = 140/281 (49%), Gaps = 12/281 (4%)

Query: 22  SLYFIVLIGGLVGVISILFLLVKM-NTRSVTTMAVINLVVVHSVFLLTVPFRLTYLIKK- 79
           +LY ++ + G  G   +L++L+K  + +S   + +INL V   + + T+P R+ Y + K 
Sbjct: 28  TLYSMISVVGFFGNGFVLYVLIKTYHKKSAFQVYMINLAVADLLCVCTLPLRVVYYVHKG 87

Query: 80  TWMFGLPFCKFVSAMLHIHMYLTFLFYVVILVTRYLIFFKCKDKVEFYRKLHAVAASAGM 139
            W+FG   C+  +  L++++Y +  F   +   R +        +    +  A     G+
Sbjct: 88  IWLFGDFLCRLSTYALYVNLYCSIFFMTAMSFFRCIAIVFPVQNINLVTQKKARFVCVGI 147

Query: 140 WTLVIVIVVPLVVSRYGIHEEYNEEHCFKFHKE-LAYTYVKIINY--MIVIFVIAVAVIL 196
           W  VI+   P ++++    +E N   CF+  ++     +V +++Y  + V F+I   +I+
Sbjct: 148 WIFVILTSSPFLMAK-PQKDEKNNTKCFEPPQDNQTKNHVLVLHYVSLFVGFIIPFVIII 206

Query: 197 LVFQVFIIMLMVQKLRHSLLSHQEFWAQLKNLFFIGVILVCFLPYQFFRIYYLNVV-THS 255
           + + + I+ L+ + ++ +L SH++    +  +      LV F+PY   R  +L+ +   +
Sbjct: 207 VCYTMIILTLLKKSMKKNLSSHKKAIGMI--MVVTAAFLVSFMPYHIQRTIHLHFLHNET 264

Query: 256 NACNSKVAFYNEIFLSVTAIS---CYDLLLFVFGGSHWFKQ 293
             C+S +     + ++++  +   C+D LL+ F G ++ K+
Sbjct: 265 KPCDSVLRMQKSVVITLSLAASNCCFDPLLYFFSGGNFRKR 305


>gi|148225857 G protein-coupled receptor 34 [Homo sapiens]
          Length = 381

 Score = 87.4 bits (215), Expect = 1e-17
 Identities = 62/288 (21%), Positives = 143/288 (49%), Gaps = 15/288 (5%)

Query: 13  DPIVTPHLISLYFIVLIGGLVGVISILFLLVKMNT-RSVTTMAVINLVVVHSVFLLTVPF 71
           + +++  L + Y ++ I GLVG I  L++ + ++  R+   + ++N+ +   + +  +PF
Sbjct: 50  EKLLSTVLTTSYSVIFIVGLVGNIIALYVFLGIHRKRNSIQIYLLNVAIADLLLIFCLPF 109

Query: 72  RLTYLIKKT-WMFGLPFCKFVSAMLHIHMYLTFLFYVVILVTRYLIFFKCKDKVEFYRKL 130
           R+ Y I +  W  G+  CK V  + +++MY++ +    I + RY+   +   + +     
Sbjct: 110 RIMYHINQNKWTLGVILCKVVGTLFYMNMYISIILLGFISLDRYIKINRSIQQRKAITTK 169

Query: 131 HAVAASAGMWTLVI---VIVVPLVVSRYGIHEEYNEEHCFKFHKELAYTYVKIINYMIVI 187
            ++     +W L +   + ++ L + + G    +N   CF +  +       I N+++V+
Sbjct: 170 QSIYVCCIVWMLALGGFLTMIILTLKKGG----HNSTMCFHYRDKHNAKGEAIFNFILVV 225

Query: 188 --FVIAVAVILLVFQVFIIMLMVQKLRHSLLSHQEFWAQLKNLFFIGVIL-VCFLPYQFF 244
             ++I + +IL   ++   +L + K R    +  ++    +N F + +I  +CF+PY  F
Sbjct: 226 MFWLIFLLIILSYIKIGKNLLRISKRRSKFPNSGKYATTARNSFIVLIIFTICFVPYHAF 285

Query: 245 RIYYLNVVTHSNACNSKVAFY--NEIFLSVTAI-SCYDLLLFVFGGSH 289
           R  Y++   + ++C  K   +  NEI L +++  SC D +++    S+
Sbjct: 286 RFIYISSQLNVSSCYWKEIVHKTNEIMLVLSSFNSCLDPVMYFLMSSN 333


>gi|4885319 G protein-coupled receptor 34 [Homo sapiens]
          Length = 381

 Score = 87.4 bits (215), Expect = 1e-17
 Identities = 62/288 (21%), Positives = 143/288 (49%), Gaps = 15/288 (5%)

Query: 13  DPIVTPHLISLYFIVLIGGLVGVISILFLLVKMNT-RSVTTMAVINLVVVHSVFLLTVPF 71
           + +++  L + Y ++ I GLVG I  L++ + ++  R+   + ++N+ +   + +  +PF
Sbjct: 50  EKLLSTVLTTSYSVIFIVGLVGNIIALYVFLGIHRKRNSIQIYLLNVAIADLLLIFCLPF 109

Query: 72  RLTYLIKKT-WMFGLPFCKFVSAMLHIHMYLTFLFYVVILVTRYLIFFKCKDKVEFYRKL 130
           R+ Y I +  W  G+  CK V  + +++MY++ +    I + RY+   +   + +     
Sbjct: 110 RIMYHINQNKWTLGVILCKVVGTLFYMNMYISIILLGFISLDRYIKINRSIQQRKAITTK 169

Query: 131 HAVAASAGMWTLVI---VIVVPLVVSRYGIHEEYNEEHCFKFHKELAYTYVKIINYMIVI 187
            ++     +W L +   + ++ L + + G    +N   CF +  +       I N+++V+
Sbjct: 170 QSIYVCCIVWMLALGGFLTMIILTLKKGG----HNSTMCFHYRDKHNAKGEAIFNFILVV 225

Query: 188 --FVIAVAVILLVFQVFIIMLMVQKLRHSLLSHQEFWAQLKNLFFIGVIL-VCFLPYQFF 244
             ++I + +IL   ++   +L + K R    +  ++    +N F + +I  +CF+PY  F
Sbjct: 226 MFWLIFLLIILSYIKIGKNLLRISKRRSKFPNSGKYATTARNSFIVLIIFTICFVPYHAF 285

Query: 245 RIYYLNVVTHSNACNSKVAFY--NEIFLSVTAI-SCYDLLLFVFGGSH 289
           R  Y++   + ++C  K   +  NEI L +++  SC D +++    S+
Sbjct: 286 RFIYISSQLNVSSCYWKEIVHKTNEIMLVLSSFNSCLDPVMYFLMSSN 333


>gi|224586796 G protein-coupled receptor 87 [Homo sapiens]
          Length = 358

 Score = 86.3 bits (212), Expect = 3e-17
 Identities = 71/294 (24%), Positives = 130/294 (44%), Gaps = 17/294 (5%)

Query: 2   PGHNTSRNSSCDPIVTPHLISLYFI--VLIGGLVGVISILFLLVKMNTRSVTTMAVINLV 59
           PG NT+ ++  D IV P L  + F+  +L+ GL      +++   +  ++     + N+V
Sbjct: 30  PGKNTTLHNEFDTIVLPVLYLIIFVASILLNGLA-----VWIFFHIRNKTSFIFYLKNIV 84

Query: 60  VVHSVFLLTVPFRLTYLIK-KTWMFGLPFCKFVSAMLHIHMYLTFLFYVVILVTRYLIFF 118
           V   +  LT PFR+ +      W F    C++ S + + +MY + +F  +I + RYL   
Sbjct: 85  VADLIMTLTFPFRIVHDAGFGPWYFKFILCRYTSVLFYANMYTSIVFLGLISIDRYLKVV 144

Query: 119 KCKDKVEFYRKLHAVAASAGMWTLVIVIVVPLVVSRYGIHEEYNEEHCFKFHKELAYTYV 178
           K       Y        S  +W ++ V+ +P ++   G   E N   C K    L   + 
Sbjct: 145 KPFGDSRMYSITFTKVLSVCVWVIMAVLSLPNIILTNGQPTEDNIHDCSKLKSPLGVKWH 204

Query: 179 KIINYMIVIFVIAVAVILLVFQVFIIMLMVQKLRHSLLSHQEFWAQLKNL-FFIGVILVC 237
             + Y+     +AV VIL+   + I   + +  R  +          +++   + V   C
Sbjct: 205 TAVTYVNSCLFVAVLVILIGCYIAISRYIHKSSRQFISQSSRKRKHNQSIRVVVAVFFTC 264

Query: 238 FLPYQFFRI----YYLNVVTHSNACNSKVAFY-NEIFLSVTAIS-CYDLLLFVF 285
           FLPY   RI     +L+ +   +A   K+ +Y  EI L ++A + C D +++ F
Sbjct: 265 FLPYHLCRIPFTFSHLDRLLDESA--QKILYYCKEITLFLSACNVCLDPIIYFF 316


>gi|148235349 G protein-coupled receptor 18 [Homo sapiens]
          Length = 331

 Score = 83.2 bits (204), Expect = 3e-16
 Identities = 60/274 (21%), Positives = 123/274 (44%), Gaps = 6/274 (2%)

Query: 26  IVLIGGLVGVISILFLLVKMNTRSVTTMAVINLVVVHSVFLLTVPFRLTYLIKKTWMFGL 85
           I +IG  V + ++         R+  T+ ++N+ +V  +F++T+PFR+ Y  K  W FG 
Sbjct: 32  IFIIGLFVNITALWVFSCTTKKRTTVTIYMMNVALVDLIFIMTLPFRMFYYAKDEWPFGE 91

Query: 86  PFCKFVSAMLHIHMYLTFLFYVVILVTRYLIFFKCKDKVEFYRKLHAVAASAGMWTLVIV 145
            FC+ + A+   +  +       I   RY+   + K   E      AV A  G+W + + 
Sbjct: 92  YFCQILGALTVFYPSIALWLLAFISADRYMAIVQPKYAKELKNTCKAVLACVGVWIMTLT 151

Query: 146 IVVPLVVSRYGIHEEYNEEHCFKFHKELAYTYVKIINYMIVIFVIAVAVILLVFQVFIIM 205
              PL++      ++     C K    +    V ++N   + F   + + +++    +I+
Sbjct: 152 TTTPLLLLYKDPDKDSTPATCLKISDIIYLKAVNVLNLTRLTFFFLIPLFIMIGCYLVII 211

Query: 206 LMVQKLRHSLLSHQEFWAQLKNLFFIGV-ILVCFLPYQFFRIYYLNVVTHSNACNSKVAF 264
             +   R S L  +     ++ +  + V +LVCF+P+      +L + T  N+ N   AF
Sbjct: 212 HNLLHGRTSKLKPKVKEKSIRIIITLLVQVLVCFMPFHIC-FAFLMLGTGENSYNPWGAF 270

Query: 265 YNEIFLSVTAISCYDLLLFVFGGSHWFKQKIIGL 298
              +   +   +C D++L+ +  S  F+ ++I +
Sbjct: 271 TTFL---MNLSTCLDVILY-YIVSKQFQARVISV 300


>gi|15029528 G protein-coupled receptor 18 [Homo sapiens]
          Length = 331

 Score = 83.2 bits (204), Expect = 3e-16
 Identities = 60/274 (21%), Positives = 123/274 (44%), Gaps = 6/274 (2%)

Query: 26  IVLIGGLVGVISILFLLVKMNTRSVTTMAVINLVVVHSVFLLTVPFRLTYLIKKTWMFGL 85
           I +IG  V + ++         R+  T+ ++N+ +V  +F++T+PFR+ Y  K  W FG 
Sbjct: 32  IFIIGLFVNITALWVFSCTTKKRTTVTIYMMNVALVDLIFIMTLPFRMFYYAKDEWPFGE 91

Query: 86  PFCKFVSAMLHIHMYLTFLFYVVILVTRYLIFFKCKDKVEFYRKLHAVAASAGMWTLVIV 145
            FC+ + A+   +  +       I   RY+   + K   E      AV A  G+W + + 
Sbjct: 92  YFCQILGALTVFYPSIALWLLAFISADRYMAIVQPKYAKELKNTCKAVLACVGVWIMTLT 151

Query: 146 IVVPLVVSRYGIHEEYNEEHCFKFHKELAYTYVKIINYMIVIFVIAVAVILLVFQVFIIM 205
              PL++      ++     C K    +    V ++N   + F   + + +++    +I+
Sbjct: 152 TTTPLLLLYKDPDKDSTPATCLKISDIIYLKAVNVLNLTRLTFFFLIPLFIMIGCYLVII 211

Query: 206 LMVQKLRHSLLSHQEFWAQLKNLFFIGV-ILVCFLPYQFFRIYYLNVVTHSNACNSKVAF 264
             +   R S L  +     ++ +  + V +LVCF+P+      +L + T  N+ N   AF
Sbjct: 212 HNLLHGRTSKLKPKVKEKSIRIIITLLVQVLVCFMPFHIC-FAFLMLGTGENSYNPWGAF 270

Query: 265 YNEIFLSVTAISCYDLLLFVFGGSHWFKQKIIGL 298
              +   +   +C D++L+ +  S  F+ ++I +
Sbjct: 271 TTFL---MNLSTCLDVILY-YIVSKQFQARVISV 300


>gi|9966851 cysteinyl leukotriene receptor 2 [Homo sapiens]
          Length = 346

 Score = 81.6 bits (200), Expect = 8e-16
 Identities = 70/306 (22%), Positives = 142/306 (46%), Gaps = 28/306 (9%)

Query: 4   HNTSRNSSCDPIVTPHLISLYFIVLIGGLVGV-ISILFLLVKMNTRSVTTMAVINLVVVH 62
           +N SRN + +         +Y I+   G++G  +SI   L      +   + ++NL +  
Sbjct: 25  NNNSRNCTIENFKREFFPIVYLIIFFWGVLGNGLSIYVFLQPYKKSTSVNVFMLNLAISD 84

Query: 63  SVFLLTVPFRLTYLIK-KTWMFGLPFCKFVSAMLHIHMYLTFLFYVVILVTRYLIFFKCK 121
            +F+ T+PFR  Y ++   W+FG   C+ +S  L+++MY +  F  V+ V R+L      
Sbjct: 85  LLFISTLPFRADYYLRGSNWIFGDLACRIMSYSLYVNMYSSIYFLTVLSVVRFLAM---- 140

Query: 122 DKVEFYRKLHAVAASAGMWTLVIVIVVPLVVSRYGIHEEYNEE----------HCFKFHK 171
             V  +R LH V +    W L  +I + ++ S   + +  +E+          + +K  K
Sbjct: 141 --VHPFRLLH-VTSIRSAWILCGIIWILIMASSIMLLDSGSEQNGSVTSCLELNLYKIAK 197

Query: 172 ELAYTYVK-IINYMIVIFVIAVAVILLVFQVFIIMLMVQKLRHSLLSHQEFWAQLKNLFF 230
                Y+  ++  ++  F +++  +L++  +  + +    LR   +SH++  A    +  
Sbjct: 198 LQTMNYIALVVGCLLPFFTLSICYLLIIRVLLKVEVPESGLR---VSHRK--ALTTIIIT 252

Query: 231 IGVILVCFLPYQFFRIYYLNVVTHSNACNSKVAFYNEIFLSVTAI-SCYDLLLFVFGGSH 289
           + +  +CFLPY   R  +L        C  ++     I L++ A  +C++ LL+ F G +
Sbjct: 253 LIIFFLCFLPYHTLRTVHL-TTWKVGLCKDRLHKALVITLALAAANACFNPLLYYFAGEN 311

Query: 290 WFKQKI 295
            FK ++
Sbjct: 312 -FKDRL 316


>gi|241982708 G-protein coupled purinergic receptor P2Y5 [Homo
           sapiens]
          Length = 344

 Score = 80.5 bits (197), Expect = 2e-15
 Identities = 76/277 (27%), Positives = 126/277 (45%), Gaps = 20/277 (7%)

Query: 23  LYFIVLIGGLVG-VISILFLLVKMNTRSVTTMAVINLVVVHSVFLLTVPFRLTYLIKKTW 81
           ++ +V + GL+   ++I   +  +  R+ TT  +INL +   +F+ T+PFR+ Y   + W
Sbjct: 23  MFSMVFVLGLISNCVAIYIFICVLKVRNETTTYMINLAMSDLLFVFTLPFRIFYFTTRNW 82

Query: 82  MFGLPFCKFVSAMLHIHMYLTFLFYVVILVTRYL-IFFKCKDKVEFYRKLHAVAASAGMW 140
            FG   CK    + + +MY + LF   I V R+L I +  K K     K +A     G+W
Sbjct: 83  PFGDLLCKISVMLFYTNMYGSILFLTCISVDRFLAIVYPFKSKT-LRTKRNAKIVCTGVW 141

Query: 141 TLVIVIVVPLVVSRYGIHEEYN--EEHCFKFHKELAY-TYVKIINYMIVIFVIAVAVIL- 196
             VI    P V  +   H + N   E CF+   E  + TY+      IVIF+  V   + 
Sbjct: 142 LTVIGGSAPAVFVQ-STHSQGNNASEACFENFPEATWKTYLS----RIVIFIEIVGFFIP 196

Query: 197 LVFQVFIIMLMVQKLRHSLLSHQEFWAQLKNLFFIGVILV----CFLPYQFFRIYYLNVV 252
           L+  V    ++++ L   +   +    + K L  I V L+    CF+PY    I Y  V 
Sbjct: 197 LILNVTCSSMVLKTLTKPVTLSRSKINKTKVLKMIFVHLIIFCFCFVPYNINLILYSLVR 256

Query: 253 THSNACNSKVAFYNEIFLSVTAIS----CYDLLLFVF 285
           T +    S VA    ++     I+    C+D +++ F
Sbjct: 257 TQTFVNCSVVAAVRTMYPITLCIAVSNCCFDPIVYYF 293


>gi|241982706 G-protein coupled purinergic receptor P2Y5 [Homo
           sapiens]
          Length = 344

 Score = 80.5 bits (197), Expect = 2e-15
 Identities = 76/277 (27%), Positives = 126/277 (45%), Gaps = 20/277 (7%)

Query: 23  LYFIVLIGGLVG-VISILFLLVKMNTRSVTTMAVINLVVVHSVFLLTVPFRLTYLIKKTW 81
           ++ +V + GL+   ++I   +  +  R+ TT  +INL +   +F+ T+PFR+ Y   + W
Sbjct: 23  MFSMVFVLGLISNCVAIYIFICVLKVRNETTTYMINLAMSDLLFVFTLPFRIFYFTTRNW 82

Query: 82  MFGLPFCKFVSAMLHIHMYLTFLFYVVILVTRYL-IFFKCKDKVEFYRKLHAVAASAGMW 140
            FG   CK    + + +MY + LF   I V R+L I +  K K     K +A     G+W
Sbjct: 83  PFGDLLCKISVMLFYTNMYGSILFLTCISVDRFLAIVYPFKSKT-LRTKRNAKIVCTGVW 141

Query: 141 TLVIVIVVPLVVSRYGIHEEYN--EEHCFKFHKELAY-TYVKIINYMIVIFVIAVAVIL- 196
             VI    P V  +   H + N   E CF+   E  + TY+      IVIF+  V   + 
Sbjct: 142 LTVIGGSAPAVFVQ-STHSQGNNASEACFENFPEATWKTYLS----RIVIFIEIVGFFIP 196

Query: 197 LVFQVFIIMLMVQKLRHSLLSHQEFWAQLKNLFFIGVILV----CFLPYQFFRIYYLNVV 252
           L+  V    ++++ L   +   +    + K L  I V L+    CF+PY    I Y  V 
Sbjct: 197 LILNVTCSSMVLKTLTKPVTLSRSKINKTKVLKMIFVHLIIFCFCFVPYNINLILYSLVR 256

Query: 253 THSNACNSKVAFYNEIFLSVTAIS----CYDLLLFVF 285
           T +    S VA    ++     I+    C+D +++ F
Sbjct: 257 TQTFVNCSVVAAVRTMYPITLCIAVSNCCFDPIVYYF 293


>gi|33695113 G-protein coupled purinergic receptor P2Y5 [Homo
           sapiens]
          Length = 344

 Score = 80.5 bits (197), Expect = 2e-15
 Identities = 76/277 (27%), Positives = 126/277 (45%), Gaps = 20/277 (7%)

Query: 23  LYFIVLIGGLVG-VISILFLLVKMNTRSVTTMAVINLVVVHSVFLLTVPFRLTYLIKKTW 81
           ++ +V + GL+   ++I   +  +  R+ TT  +INL +   +F+ T+PFR+ Y   + W
Sbjct: 23  MFSMVFVLGLISNCVAIYIFICVLKVRNETTTYMINLAMSDLLFVFTLPFRIFYFTTRNW 82

Query: 82  MFGLPFCKFVSAMLHIHMYLTFLFYVVILVTRYL-IFFKCKDKVEFYRKLHAVAASAGMW 140
            FG   CK    + + +MY + LF   I V R+L I +  K K     K +A     G+W
Sbjct: 83  PFGDLLCKISVMLFYTNMYGSILFLTCISVDRFLAIVYPFKSKT-LRTKRNAKIVCTGVW 141

Query: 141 TLVIVIVVPLVVSRYGIHEEYN--EEHCFKFHKELAY-TYVKIINYMIVIFVIAVAVIL- 196
             VI    P V  +   H + N   E CF+   E  + TY+      IVIF+  V   + 
Sbjct: 142 LTVIGGSAPAVFVQ-STHSQGNNASEACFENFPEATWKTYLS----RIVIFIEIVGFFIP 196

Query: 197 LVFQVFIIMLMVQKLRHSLLSHQEFWAQLKNLFFIGVILV----CFLPYQFFRIYYLNVV 252
           L+  V    ++++ L   +   +    + K L  I V L+    CF+PY    I Y  V 
Sbjct: 197 LILNVTCSSMVLKTLTKPVTLSRSKINKTKVLKMIFVHLIIFCFCFVPYNINLILYSLVR 256

Query: 253 THSNACNSKVAFYNEIFLSVTAIS----CYDLLLFVF 285
           T +    S VA    ++     I+    C+D +++ F
Sbjct: 257 TQTFVNCSVVAAVRTMYPITLCIAVSNCCFDPIVYYF 293


>gi|125625354 P2Y14 receptor [Homo sapiens]
          Length = 338

 Score = 78.6 bits (192), Expect = 7e-15
 Identities = 70/281 (24%), Positives = 128/281 (45%), Gaps = 12/281 (4%)

Query: 15  IVTPHLIS-LYFIVLIGGLV--GVISILFLLVKMNTRSVTTMAVINLVVVHSVFLLTVPF 71
           ++T  +I  LY +V I G++  GV   +F  V  +   +  +   N+V+   V  LT PF
Sbjct: 19  LITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFIIYLK--NIVIADFVMSLTFPF 76

Query: 72  R-LTYLIKKTWMFGLPFCKFVSAMLHIHMYLTFLFYVVILVTRYLIFFKCKDKVEFYRKL 130
           + L       W   +  C+  + + +++MY++ +F+ +I   RY    K           
Sbjct: 77  KILGDSGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISFDRYYKIVKPLWTSFIQSVS 136

Query: 131 HAVAASAGMWTLVIVIVVPLVVSRYGIHEEYNEEHCFKFHKELAYTYVKIINYMIVIFVI 190
           ++   S  +W L++++ VP ++       E  +  C +   EL   + K  NY+ V    
Sbjct: 137 YSKLLSVIVWMLMLLLAVPNIILTNQSVREVTQIKCIELKSELGRKWHKASNYIFVAIFW 196

Query: 191 AVAVILLVFQVFII-MLMVQKLRHSLLSHQEFWAQLKNLF-FIGVILVCFLPYQFFRIYY 248
            V ++L+VF   I   +    L+ S  S        +N+F  + V  VCF+PY   RI Y
Sbjct: 197 IVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFSIVFVFFVCFVPYHIARIPY 256

Query: 249 LNVVTHSN-ACNSK--VAFYNEIFLSVTAIS-CYDLLLFVF 285
               T ++ +C SK  + +  E  L ++A + C D +++ F
Sbjct: 257 TKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFF 297


>gi|125625352 P2Y14 receptor [Homo sapiens]
          Length = 338

 Score = 78.6 bits (192), Expect = 7e-15
 Identities = 70/281 (24%), Positives = 128/281 (45%), Gaps = 12/281 (4%)

Query: 15  IVTPHLIS-LYFIVLIGGLV--GVISILFLLVKMNTRSVTTMAVINLVVVHSVFLLTVPF 71
           ++T  +I  LY +V I G++  GV   +F  V  +   +  +   N+V+   V  LT PF
Sbjct: 19  LITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFIIYLK--NIVIADFVMSLTFPF 76

Query: 72  R-LTYLIKKTWMFGLPFCKFVSAMLHIHMYLTFLFYVVILVTRYLIFFKCKDKVEFYRKL 130
           + L       W   +  C+  + + +++MY++ +F+ +I   RY    K           
Sbjct: 77  KILGDSGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISFDRYYKIVKPLWTSFIQSVS 136

Query: 131 HAVAASAGMWTLVIVIVVPLVVSRYGIHEEYNEEHCFKFHKELAYTYVKIINYMIVIFVI 190
           ++   S  +W L++++ VP ++       E  +  C +   EL   + K  NY+ V    
Sbjct: 137 YSKLLSVIVWMLMLLLAVPNIILTNQSVREVTQIKCIELKSELGRKWHKASNYIFVAIFW 196

Query: 191 AVAVILLVFQVFII-MLMVQKLRHSLLSHQEFWAQLKNLF-FIGVILVCFLPYQFFRIYY 248
            V ++L+VF   I   +    L+ S  S        +N+F  + V  VCF+PY   RI Y
Sbjct: 197 IVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFSIVFVFFVCFVPYHIARIPY 256

Query: 249 LNVVTHSN-ACNSK--VAFYNEIFLSVTAIS-CYDLLLFVF 285
               T ++ +C SK  + +  E  L ++A + C D +++ F
Sbjct: 257 TKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFF 297


>gi|52426789 oxoglutarate (alpha-ketoglutarate) receptor 1 [Homo
           sapiens]
          Length = 337

 Score = 77.8 bits (190), Expect = 1e-14
 Identities = 63/294 (21%), Positives = 121/294 (41%), Gaps = 10/294 (3%)

Query: 14  PIVTPHLISLYFIVLIGGLVG-VISILFLLVKMNTRSVTTMAVINLVVVHSVFLLTVPFR 72
           P+   +L  +Y I+ + G  G  + I   + KM     +T+ ++NL     ++L ++PF 
Sbjct: 30  PLKMHYLPVIYGIIFLVGFPGNAVVISTYIFKMRPWKSSTIIMLNLACTDLLYLTSLPFL 89

Query: 73  LTYLIK-KTWMFGLPFCKFVSAMLHIHMYLTFLFYVVILVTRYLIFFKCKDKVEFYRKLH 131
           + Y    + W+FG   CKF+    H ++Y + LF     + RY +          ++   
Sbjct: 90  IHYYASGENWIFGDFMCKFIRFSFHFNLYSSILFLTCFSIFRYCVIIHPMSCFSIHKTRC 149

Query: 132 AVAASAGMWTLVIVIVVPLVVSRYGIHEEYNEEHCFKFHKELAYTYVKIINYMI--VIFV 189
           AV A A +W + +V V+P+       +   N   C           +K  N ++    F 
Sbjct: 150 AVVACAVVWIISLVAVIPMTFLITSTNRT-NRSACLDLTSSDELNTIKWYNLILTATTFC 208

Query: 190 IAVAVILLVFQVFIIMLMVQKLRHSLLSHQEFWAQLKNLFFIGVILVCFLPYQFFRIYYL 249
           + + ++ L +   I  L       S L  +   A+   +  +    VCFLP+   R+  +
Sbjct: 209 LPLVIVTLCYTTIIHTLTHGLQTDSCLKQK---ARRLTILLLLAFYVCFLPFHILRVIRI 265

Query: 250 NVVTHSNACNSKVAFYNEIFLS--VTAISCYDLLLFVFGGSHWFKQKIIGLWNC 301
                S +C+ +   +    +S  + A++ +  LL     S  F+Q +     C
Sbjct: 266 ESRLLSISCSIENQIHEAYIVSRPLAALNTFGNLLLYVVVSDNFQQAVCSTVRC 319


>gi|4557857 somatostatin receptor 1 [Homo sapiens]
          Length = 391

 Score = 77.4 bits (189), Expect = 1e-14
 Identities = 58/264 (21%), Positives = 128/264 (48%), Gaps = 23/264 (8%)

Query: 2   PGHNTSRNSSC-DPIVTPHLIS-LYFIVLIGGLVGVISILFLLVKM-NTRSVTTMAVINL 58
           PG N S+N +  +   +  LIS +Y +V + GL G   +++++++    ++ T + ++NL
Sbjct: 41  PGRNASQNGTLSEGQGSAILISFIYSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNL 100

Query: 59  VVVHSVFLLTVPFRLTYLIKKTWMFGLPFCKFVSAMLHIHMYLTFLFYVVILVTRYLIFF 118
            +   + +L+VPF +T  + + W FG   C+ V ++  ++M+ +     V+ V RY+   
Sbjct: 101 AIADELLMLSVPFLVTSTLLRHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVV 160

Query: 119 KCKDKVEFYRKLHAVAASAGMWTLVIVIVVPLVVSRYGIHEEYNEEHCFKFHKELAYTYV 178
                  + R   A   + G+W L +++++P+VV             C     E A  ++
Sbjct: 161 HPIKAARYRRPTVAKVVNLGVWVLSLLVILPIVVFSRTAANSDGTVACNMLMPEPAQRWL 220

Query: 179 K--IINYMIVIFVIAVAVILLVFQVFIIMLMVQKLRHSLLSHQEFWAQLKN--------- 227
              ++   ++ F++ V  I L +     +L++ K+R  +++ +  W Q K          
Sbjct: 221 VGFVLYTFLMGFLLPVGAICLCY-----VLIIAKMR--MVALKAGWQQRKRSERKITLMV 273

Query: 228 LFFIGVILVCFLPYQFFRIYYLNV 251
           +  + V ++C++P  F+ +  +NV
Sbjct: 274 MMVVMVFVICWMP--FYVVQLVNV 295


>gi|238814307 G protein-coupled receptor 17 isoform b [Homo sapiens]
          Length = 339

 Score = 76.6 bits (187), Expect = 2e-14
 Identities = 66/280 (23%), Positives = 125/280 (44%), Gaps = 16/280 (5%)

Query: 14  PIVTPHLISLYFIVLIGGLVGVISILFLLVKMNTRSV-TTMAVINLVVVHSVFLLTVPFR 72
           P+      S Y +  I  LVG    L+L ++ +       + +++L V     +L +P R
Sbjct: 28  PLENMLFASFYLLDFILALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLSCVLVLPTR 87

Query: 73  LTYLIKKT-WMFGLPFCKFVSAMLHIHMYLTFLFYVVILVTRYLIFFKCKDKVEFYRKLH 131
           L Y      W FG   C+    + +++MY +  F   I   R+L        ++  R L+
Sbjct: 88  LVYHFSGNHWPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLY 147

Query: 132 AVAASAGMWTLVIVIVVPLVVSRYGIHEEYNEEHCFKFHKELAYTYVKIINYMIVIFVIA 191
           A  A A +W +V V + PL+VS   +   +    C + ++E      K  ++ +V   +A
Sbjct: 148 AHLACAFLWVVVAVAMAPLLVSPQTVQTNHTVV-CLQLYRE------KASHHALVSLAVA 200

Query: 192 VAVILLVFQVFIIMLMVQKLRHSLLSHQEFWAQLKNLFFI--GVILVCFLPYQFFR-IYY 248
                 +  V   +L+++ LR  L   +    +   +  I   + LVCF+PY   R +Y 
Sbjct: 201 F-TFPFITTVTCYLLIIRSLRQGLRVEKRLKTKAVRMIAIVLAIFLVCFVPYHVNRSVYV 259

Query: 249 LNVVTHSNACNSK--VAFYNEIFLSVTAIS-CYDLLLFVF 285
           L+  +H  +C ++  +A  N I   +T+++   D +++ F
Sbjct: 260 LHYRSHGASCATQRILALANRITSCLTSLNGALDPIMYFF 299


>gi|238814305 G protein-coupled receptor 17 isoform b [Homo sapiens]
          Length = 339

 Score = 76.6 bits (187), Expect = 2e-14
 Identities = 66/280 (23%), Positives = 125/280 (44%), Gaps = 16/280 (5%)

Query: 14  PIVTPHLISLYFIVLIGGLVGVISILFLLVKMNTRSV-TTMAVINLVVVHSVFLLTVPFR 72
           P+      S Y +  I  LVG    L+L ++ +       + +++L V     +L +P R
Sbjct: 28  PLENMLFASFYLLDFILALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLSCVLVLPTR 87

Query: 73  LTYLIKKT-WMFGLPFCKFVSAMLHIHMYLTFLFYVVILVTRYLIFFKCKDKVEFYRKLH 131
           L Y      W FG   C+    + +++MY +  F   I   R+L        ++  R L+
Sbjct: 88  LVYHFSGNHWPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLY 147

Query: 132 AVAASAGMWTLVIVIVVPLVVSRYGIHEEYNEEHCFKFHKELAYTYVKIINYMIVIFVIA 191
           A  A A +W +V V + PL+VS   +   +    C + ++E      K  ++ +V   +A
Sbjct: 148 AHLACAFLWVVVAVAMAPLLVSPQTVQTNHTVV-CLQLYRE------KASHHALVSLAVA 200

Query: 192 VAVILLVFQVFIIMLMVQKLRHSLLSHQEFWAQLKNLFFI--GVILVCFLPYQFFR-IYY 248
                 +  V   +L+++ LR  L   +    +   +  I   + LVCF+PY   R +Y 
Sbjct: 201 F-TFPFITTVTCYLLIIRSLRQGLRVEKRLKTKAVRMIAIVLAIFLVCFVPYHVNRSVYV 259

Query: 249 LNVVTHSNACNSK--VAFYNEIFLSVTAIS-CYDLLLFVF 285
           L+  +H  +C ++  +A  N I   +T+++   D +++ F
Sbjct: 260 LHYRSHGASCATQRILALANRITSCLTSLNGALDPIMYFF 299


>gi|4885301 G protein-coupled receptor 17 isoform a [Homo sapiens]
          Length = 367

 Score = 76.6 bits (187), Expect = 2e-14
 Identities = 66/280 (23%), Positives = 125/280 (44%), Gaps = 16/280 (5%)

Query: 14  PIVTPHLISLYFIVLIGGLVGVISILFLLVKMNTRSV-TTMAVINLVVVHSVFLLTVPFR 72
           P+      S Y +  I  LVG    L+L ++ +       + +++L V     +L +P R
Sbjct: 56  PLENMLFASFYLLDFILALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLSCVLVLPTR 115

Query: 73  LTYLIKKT-WMFGLPFCKFVSAMLHIHMYLTFLFYVVILVTRYLIFFKCKDKVEFYRKLH 131
           L Y      W FG   C+    + +++MY +  F   I   R+L        ++  R L+
Sbjct: 116 LVYHFSGNHWPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLY 175

Query: 132 AVAASAGMWTLVIVIVVPLVVSRYGIHEEYNEEHCFKFHKELAYTYVKIINYMIVIFVIA 191
           A  A A +W +V V + PL+VS   +   +    C + ++E      K  ++ +V   +A
Sbjct: 176 AHLACAFLWVVVAVAMAPLLVSPQTVQTNHTVV-CLQLYRE------KASHHALVSLAVA 228

Query: 192 VAVILLVFQVFIIMLMVQKLRHSLLSHQEFWAQLKNLFFI--GVILVCFLPYQFFR-IYY 248
                 +  V   +L+++ LR  L   +    +   +  I   + LVCF+PY   R +Y 
Sbjct: 229 F-TFPFITTVTCYLLIIRSLRQGLRVEKRLKTKAVRMIAIVLAIFLVCFVPYHVNRSVYV 287

Query: 249 LNVVTHSNACNSK--VAFYNEIFLSVTAIS-CYDLLLFVF 285
           L+  +H  +C ++  +A  N I   +T+++   D +++ F
Sbjct: 288 LHYRSHGASCATQRILALANRITSCLTSLNGALDPIMYFF 327


>gi|238814302 G protein-coupled receptor 17 isoform a [Homo sapiens]
          Length = 367

 Score = 76.6 bits (187), Expect = 2e-14
 Identities = 66/280 (23%), Positives = 125/280 (44%), Gaps = 16/280 (5%)

Query: 14  PIVTPHLISLYFIVLIGGLVGVISILFLLVKMNTRSV-TTMAVINLVVVHSVFLLTVPFR 72
           P+      S Y +  I  LVG    L+L ++ +       + +++L V     +L +P R
Sbjct: 56  PLENMLFASFYLLDFILALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLSCVLVLPTR 115

Query: 73  LTYLIKKT-WMFGLPFCKFVSAMLHIHMYLTFLFYVVILVTRYLIFFKCKDKVEFYRKLH 131
           L Y      W FG   C+    + +++MY +  F   I   R+L        ++  R L+
Sbjct: 116 LVYHFSGNHWPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLY 175

Query: 132 AVAASAGMWTLVIVIVVPLVVSRYGIHEEYNEEHCFKFHKELAYTYVKIINYMIVIFVIA 191
           A  A A +W +V V + PL+VS   +   +    C + ++E      K  ++ +V   +A
Sbjct: 176 AHLACAFLWVVVAVAMAPLLVSPQTVQTNHTVV-CLQLYRE------KASHHALVSLAVA 228

Query: 192 VAVILLVFQVFIIMLMVQKLRHSLLSHQEFWAQLKNLFFI--GVILVCFLPYQFFR-IYY 248
                 +  V   +L+++ LR  L   +    +   +  I   + LVCF+PY   R +Y 
Sbjct: 229 F-TFPFITTVTCYLLIIRSLRQGLRVEKRLKTKAVRMIAIVLAIFLVCFVPYHVNRSVYV 287

Query: 249 LNVVTHSNACNSK--VAFYNEIFLSVTAIS-CYDLLLFVF 285
           L+  +H  +C ++  +A  N I   +T+++   D +++ F
Sbjct: 288 LHYRSHGASCATQRILALANRITSCLTSLNGALDPIMYFF 327


>gi|14211849 putative purinergic receptor FKSG79 [Homo sapiens]
          Length = 333

 Score = 76.6 bits (187), Expect = 2e-14
 Identities = 70/283 (24%), Positives = 124/283 (43%), Gaps = 35/283 (12%)

Query: 24  YFIVLIGGLVGVISILFLL---VKMNTRSVTTMAVINLVVVHSVFLLTVPFRLTYLIKKT 80
           Y ++L+ GL+G I  L++    +K   R+V  M  INL +   + +L++P R+ Y +   
Sbjct: 26  YTVILVPGLIGNILALWVFYGYMKETKRAVIFM--INLAIADLLQVLSLPLRIFYYLNHD 83

Query: 81  WMFGLPFCKFVSAMLHIHMYLTFLFYVVILVTRYLI------FFKCKDKVEFYRKLHAVA 134
           W FG   C F   + +++MY +  F V I V R+        F  CK K + Y       
Sbjct: 84  WPFGPGLCMFCFYLKYVNMYASIYFLVCISVRRFWFLMYPFRFHDCKQKYDLY------- 136

Query: 135 ASAGMWTLVIVIVVPLVVSRYGIHEEYNEEHCF----KFHKELAYTYVKIINYMIVIFVI 190
            S   W ++ +  V   + R       N   CF      +  LA + V +    ++ FV 
Sbjct: 137 ISIAGWLIICLACVLFPLLRTSDDTSGNRTKCFVDLPTRNVNLAQSVVMMTIGELIGFVT 196

Query: 191 AVAVILLVFQVFIIMLMVQKLRHSLLSHQEFWAQLKNLFFI----GVILVCFLPYQF-FR 245
            + ++L     +     V  L+      Q+   + K L  I    GV L+CF PY F F 
Sbjct: 197 PLLIVL-----YCTWKTVLSLQDKYPMAQDLGEKQKALKMILTCAGVFLICFAPYHFSFP 251

Query: 246 IYYLNVVTHSNACNSK--VAFYNEIFLSVTAI-SCYDLLLFVF 285
           + +L       +C ++  +  ++ + L + ++ SC D +++ F
Sbjct: 252 LDFLVKSNEIKSCLARRVILIFHSVALCLASLNSCLDPVIYYF 294


>gi|53828924 G protein-coupled receptor 7 [Homo sapiens]
          Length = 328

 Score = 75.9 bits (185), Expect = 4e-14
 Identities = 59/287 (20%), Positives = 126/287 (43%), Gaps = 34/287 (11%)

Query: 2   PGHNTSRNSSCDPIVTPHLISL---YFIVLIGGLVGVISILFLLVKM-NTRSVTTMAVIN 57
           P  + S  S+  P+  P  +++   Y ++   GL G  ++L++L++    ++VT + ++N
Sbjct: 19  PALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILN 78

Query: 58  LVVVHSVFLLTVPFRLTYLIKKTWMFGLPFCKFVSAMLHIHMYLTFLFYVVILVTRYLIF 117
           L +   +F L +P  +   + + W FG   CK + A+   + + +  F  V+   RYL+ 
Sbjct: 79  LAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVV 138

Query: 118 FKCKDKVEFYRKLH--AVAASAGMWTLVIVIVVPLVVSRYGIHEEYNEEHCFKFHKELAY 175
               +      + +  A A S  +W +V ++V+P  V      E+   +    F +  A+
Sbjct: 139 LATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAF 198

Query: 176 TYVKIINYMIVI-FVIAVAVILLVFQVFIIMLMVQKLRHSLLSHQEFWAQLKN------L 228
            +     Y +V+ F I V+ I +++   +  L   +L     SH +   + K       +
Sbjct: 199 WWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLD----SHAKALERAKKRVTFLVV 254

Query: 229 FFIGVILVCFLPYQFFRI-----------------YYLNVVTHSNAC 258
             + V L+C+ PY    +                 Y++  ++++N+C
Sbjct: 255 AILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSC 301


>gi|4557859 somatostatin receptor 2 [Homo sapiens]
          Length = 369

 Score = 75.5 bits (184), Expect = 6e-14
 Identities = 55/274 (20%), Positives = 125/274 (45%), Gaps = 13/274 (4%)

Query: 20  LISLYFIVLIGGLVGVISILFLLVKM-NTRSVTTMAVINLVVVHSVFLLTVPFRLTYLIK 78
           L  +YF+V I GL G   +++++++    +++T + ++NL +   +F+L +PF    +  
Sbjct: 46  LTFIYFVVCIIGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVAL 105

Query: 79  KTWMFGLPFCKFVSAMLHIHMYLTFLFYVVILVTRYLIFFKCKDKVEFYRKLHAVAASAG 138
             W FG   C+ V  +  I+ + +     V+ + RYL         ++ R   A   +  
Sbjct: 106 VHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMITMA 165

Query: 139 MWTLVIVIVVPLVVSRYGIHEEYNEEHC-FKFHKELAYTYVKIINYMIVI-FVIAVAVIL 196
           +W + +++++P+++       ++    C   +  E    Y   I Y  ++ F++ + +I 
Sbjct: 166 VWGVSLLVILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFIIYTFILGFLVPLTIIC 225

Query: 197 LVFQVFIIMLMVQKLRHSLLSHQEFWAQLKNL--FFIGVILVCFLPYQFFRIYYLNVVTH 254
           L +   II +    +R      ++   ++  +    + V + C+LP+     Y  NV + 
Sbjct: 226 LCYLFIIIKVKSSGIRVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPF-----YIFNVSSV 280

Query: 255 SNACNSKVA---FYNEIFLSVTAISCYDLLLFVF 285
           S A +   A    ++ + +   A SC + +L+ F
Sbjct: 281 SMAISPTPALKGMFDFVVVLTYANSCANPILYAF 314


>gi|39725940 opioid receptor, kappa 1 [Homo sapiens]
          Length = 380

 Score = 73.6 bits (179), Expect = 2e-13
 Identities = 56/259 (21%), Positives = 118/259 (45%), Gaps = 8/259 (3%)

Query: 14  PIVTPHLISLYFIVLIGGLVGVISILFLLVKMNT-RSVTTMAVINLVVVHSVFLLTVPFR 72
           P +   + ++Y +V + GLVG   ++F++++    ++ T + + NL +  ++   T+PF+
Sbjct: 56  PAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQ 115

Query: 73  LTYLIKKTWMFGLPFCKFVSAMLHIHMYLTFLFYVVILVTRYLIFFKCKDKVEFYRKLHA 132
            T  +  +W FG   CK V ++ + +M+ +     ++ V RY+        ++F   L A
Sbjct: 116 STVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKA 175

Query: 133 VAASAGMWTLVIVI-VVPLVVSRYGIHEEYNEEHCFKFHKELAYTYVKI---INYMIVIF 188
              +  +W L   + +  +V+    + E+ +   C     +  Y++  +   I   I  F
Sbjct: 176 KIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAF 235

Query: 189 VIAVAVILLVFQVFIIMLMVQKLRHSLLSHQEFWAQLKNLFF--IGVILVCFLP-YQFFR 245
           VI V +I++ + + I+ L   +L            ++  L    + V +VC+ P + F  
Sbjct: 236 VIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFIL 295

Query: 246 IYYLNVVTHSNACNSKVAF 264
           +  L   +HS A  S   F
Sbjct: 296 VEALGSTSHSTAALSSYYF 314


>gi|153792776 G protein-coupled receptor 171 [Homo sapiens]
          Length = 319

 Score = 73.6 bits (179), Expect = 2e-13
 Identities = 60/284 (21%), Positives = 135/284 (47%), Gaps = 20/284 (7%)

Query: 24  YFIVLIGGLVGVISILFLLVKMNTRS-VTTMAVINLVVVHSVFLLTVPFRLTY-LIKKTW 81
           +++V + G++G     +  ++ NT     ++ +INL+    +  L +P ++   L    W
Sbjct: 21  FYLVFLVGIIGSCFATWAFIQKNTNHRCVSIYLINLLTADFLLTLALPVKIVVDLGVAPW 80

Query: 82  MFGLPFCKFVSAMLHIHMYLTFLFYVVILVTRYL-IFFKCKDKVEFYRKLH---AVAASA 137
              +  C+  + +++I+MYL+ +F   + + R L +   CK     YR      A   S 
Sbjct: 81  KLKIFHCQVTACLIYINMYLSIIFLAFVSIDRCLQLTHSCK----IYRIQEPGFAKMIST 136

Query: 138 GMWTLVIVIVVPLVVSRYGIHEEYNEEHCFKFHKELAYTYVKIINYMIVIFVIAVAVILL 197
            +W +V++I+VP ++      +E +   C +F KE    +  + N++ V   +  + I+L
Sbjct: 137 VVWLMVLLIMVPNMMIPIKDIKEKSNVGCMEFKKEFGRNWHLLTNFICVAIFLNFSAIIL 196

Query: 198 VFQVFIIMLMVQKLRHSLLSHQEFWAQLKNLFFIGV-ILVCFLPYQFFRI-YYLNVVTHS 255
           +    +I  + +   +   ++      L N+  +    ++CF+PY   RI Y L+     
Sbjct: 197 ISNCLVIRQLYRNKDNE--NYPNVKKALINILLVTTGYIICFVPYHIVRIPYTLSQTEVI 254

Query: 256 NACNSKVAFYN----EIFLSVTAISCYDLLLFVFGGSHWFKQKI 295
             C+++++ +      + L+V+ + C+D +L+ +  S  F+ K+
Sbjct: 255 TDCSTRISLFKAKEATLLLAVSNL-CFDPILY-YHLSKAFRSKV 296


>gi|4885311 lysophosphatidic acid receptor 4 [Homo sapiens]
          Length = 370

 Score = 73.2 bits (178), Expect = 3e-13
 Identities = 73/279 (26%), Positives = 126/279 (45%), Gaps = 24/279 (8%)

Query: 22  SLYFIVLIGGLV-GVISILFLLVKMNTRSVTTMAVINLVVVHSVFLLTVPFRLTYLIKKT 80
           ++Y +V I GL+   +S+     +M  RS T + + NL V   +F+ T+PF++ Y   + 
Sbjct: 44  AVYSVVFILGLITNSVSLFVFCFRMKMRSETAIFITNLAVSDLLFVCTLPFKIFYNFNRH 103

Query: 81  WMFGLPFCKFVSAMLHIHMYLTFLFYVVILVTRYL-IFFKCKDKVEFYRKLHAVAASAGM 139
           W FG   CK        ++Y + LF   I V R+L I +  + +    R+  A+   AG+
Sbjct: 104 WPFGDTLCKISGTAFLTNIYGSMLFLTCISVDRFLAIVYPFRSRTIRTRRNSAIVC-AGV 162

Query: 140 WTLVIVIVVPLVVSRYGIHEEYN-EEHCFK-FHKELAYTYVKIINYMIVIFVIAVAVIL- 196
           W  ++V+   +  S +      N    CF+ F K +  TY+      I IF+  V  I+ 
Sbjct: 163 W--ILVLSGGISASLFSTTNVNNATTTCFEGFSKRVWKTYLS----KITIFIEVVGFIIP 216

Query: 197 LVFQVFIIMLMVQKLRHSLLSHQEFWAQLKNLFFI----GVILVCFLPYQFFRIYYLNVV 252
           L+  V    ++++ LR      Q    + K L  I     V +VCF+PY    + +L  +
Sbjct: 217 LILNVSCSSVVLRTLRKPATLSQIGTNKKKVLKMITVHMAVFVVCFVPYN--SVLFLYAL 274

Query: 253 THSNA-CNSKVAFYNEIFLSVTAI-----SCYDLLLFVF 285
             S A  N  +  + +I   +T        C+D  ++ F
Sbjct: 275 VRSQAITNCFLERFAKIMYPITLCLATLNCCFDPFIYYF 313


>gi|30581170 CC chemokine receptor 3 [Homo sapiens]
          Length = 355

 Score = 72.8 bits (177), Expect = 4e-13
 Identities = 43/177 (24%), Positives = 83/177 (46%), Gaps = 3/177 (1%)

Query: 23  LYFIVLIGGLVGVISILFLLVKMNT-RSVTTMAVINLVVVHSVFLLTVPFRLTYLIKKTW 81
           LY +V   GL+G + ++ +L+K    R +T + ++NL +   +FL+T+PF + Y+    W
Sbjct: 40  LYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNW 99

Query: 82  MFGLPFCKFVSAMLHIHMYLTFLFYVVILVTRYLIFFKCKDKVEFYRKLHAVAASAGMWT 141
           +FG   CK +S   H  +Y    F +++ + RYL        +        V  S   W 
Sbjct: 100 VFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWG 159

Query: 142 LVIVIVVPLVVSRYGIHEEYNEEHCFKFHKE-LAYTYVKIINYMIVIFVIAVAVILL 197
           L ++  +P  +  Y   E + E  C   + E   Y++       + IF + + ++++
Sbjct: 160 LAVLAALPEFIF-YETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVM 215


>gi|4502637 CC chemokine receptor 3 [Homo sapiens]
          Length = 355

 Score = 72.8 bits (177), Expect = 4e-13
 Identities = 43/177 (24%), Positives = 83/177 (46%), Gaps = 3/177 (1%)

Query: 23  LYFIVLIGGLVGVISILFLLVKMNT-RSVTTMAVINLVVVHSVFLLTVPFRLTYLIKKTW 81
           LY +V   GL+G + ++ +L+K    R +T + ++NL +   +FL+T+PF + Y+    W
Sbjct: 40  LYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNW 99

Query: 82  MFGLPFCKFVSAMLHIHMYLTFLFYVVILVTRYLIFFKCKDKVEFYRKLHAVAASAGMWT 141
           +FG   CK +S   H  +Y    F +++ + RYL        +        V  S   W 
Sbjct: 100 VFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWG 159

Query: 142 LVIVIVVPLVVSRYGIHEEYNEEHCFKFHKE-LAYTYVKIINYMIVIFVIAVAVILL 197
           L ++  +P  +  Y   E + E  C   + E   Y++       + IF + + ++++
Sbjct: 160 LAVLAALPEFIF-YETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVM 215


>gi|31881792 leukotriene B4 receptor [Homo sapiens]
          Length = 352

 Score = 72.4 bits (176), Expect = 5e-13
 Identities = 53/212 (25%), Positives = 94/212 (44%), Gaps = 6/212 (2%)

Query: 9   NSSCDPIVTPHLISLYFIVLIG-----GLVGVISILFLLVK-MNTRSVTTMAVINLVVVH 62
           +S+  P +    ISL  I+L+      GL G   +++ ++K M  RSVT + V+NL +  
Sbjct: 5   SSAAPPSLGVEFISLLAIILLSVALAVGLPGNSFVVWSILKRMQKRSVTALMVLNLALAD 64

Query: 63  SVFLLTVPFRLTYLIKKTWMFGLPFCKFVSAMLHIHMYLTFLFYVVILVTRYLIFFKCKD 122
              LLT PF L +L + TW FGL  C+    +  + MY + L    + + R L   +   
Sbjct: 65  LAVLLTAPFFLHFLAQGTWSFGLAGCRLCHYVCGVSMYASVLLITAMSLDRSLAVARPFV 124

Query: 123 KVEFYRKLHAVAASAGMWTLVIVIVVPLVVSRYGIHEEYNEEHCFKFHKELAYTYVKIIN 182
             +   K  A    AG+W L  ++  P++  R  +  + N   CF  +    +    +I 
Sbjct: 125 SQKLRTKAMARRVLAGIWVLSFLLATPVLAYRTVVPWKTNMSLCFPRYPSEGHRAFHLIF 184

Query: 183 YMIVIFVIAVAVILLVFQVFIIMLMVQKLRHS 214
             +  F++    ++  +      L  ++ R S
Sbjct: 185 EAVTGFLLPFLAVVASYSDIGRRLQARRFRRS 216


>gi|221218998 leukotriene B4 receptor [Homo sapiens]
          Length = 352

 Score = 72.4 bits (176), Expect = 5e-13
 Identities = 53/212 (25%), Positives = 94/212 (44%), Gaps = 6/212 (2%)

Query: 9   NSSCDPIVTPHLISLYFIVLIG-----GLVGVISILFLLVK-MNTRSVTTMAVINLVVVH 62
           +S+  P +    ISL  I+L+      GL G   +++ ++K M  RSVT + V+NL +  
Sbjct: 5   SSAAPPSLGVEFISLLAIILLSVALAVGLPGNSFVVWSILKRMQKRSVTALMVLNLALAD 64

Query: 63  SVFLLTVPFRLTYLIKKTWMFGLPFCKFVSAMLHIHMYLTFLFYVVILVTRYLIFFKCKD 122
              LLT PF L +L + TW FGL  C+    +  + MY + L    + + R L   +   
Sbjct: 65  LAVLLTAPFFLHFLAQGTWSFGLAGCRLCHYVCGVSMYASVLLITAMSLDRSLAVARPFV 124

Query: 123 KVEFYRKLHAVAASAGMWTLVIVIVVPLVVSRYGIHEEYNEEHCFKFHKELAYTYVKIIN 182
             +   K  A    AG+W L  ++  P++  R  +  + N   CF  +    +    +I 
Sbjct: 125 SQKLRTKAMARRVLAGIWVLSFLLATPVLAYRTVVPWKTNMSLCFPRYPSEGHRAFHLIF 184

Query: 183 YMIVIFVIAVAVILLVFQVFIIMLMVQKLRHS 214
             +  F++    ++  +      L  ++ R S
Sbjct: 185 EAVTGFLLPFLAVVASYSDIGRRLQARRFRRS 216


>gi|4502631 chemokine (C-C motif) receptor 1 [Homo sapiens]
          Length = 355

 Score = 71.2 bits (173), Expect = 1e-12
 Identities = 51/208 (24%), Positives = 94/208 (45%), Gaps = 23/208 (11%)

Query: 23  LYFIVLIGGLVGVISILFLLVKMNT-RSVTTMAVINLVVVHSVFLLTVPFRLTYLIKKTW 81
           LY +V + GLVG I ++ +LV+    +++T++ ++NL +   +FL T+PF + Y +K  W
Sbjct: 40  LYSLVFVIGLVGNILVVLVLVQYKRLKNMTSIYLLNLAISDLLFLFTLPFWIDYKLKDDW 99

Query: 82  MFGLPFCKFVSAMLHIHMYLTFLFYVVILVTRYLIFFKCKDKVEFYRKLHAVAASAGMWT 141
           +FG   CK +S   +  +Y    F +++ + RYL        +        V  S  +W 
Sbjct: 100 VFGDAMCKILSGFYYTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIIIWA 159

Query: 142 LVIVIVVP-------------LVVSRYGIHEEYNEEHCFKFHKELAYTYVKIINYMIVIF 188
           L I+  +P                S +  HE   E   F+  K   +  V  +  MI+ +
Sbjct: 160 LAILASMPGLYFSKTQWEFTHHTCSLHFPHESLREWKLFQALKLNLFGLVLPLLVMIICY 219

Query: 189 VIAVAVIL---------LVFQVFIIMLM 207
              + ++L          V  +F+IM++
Sbjct: 220 TGIIKILLRRPNEKKSKAVRLIFVIMII 247


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.337    0.147    0.467 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,771,918
Number of Sequences: 37866
Number of extensions: 356946
Number of successful extensions: 2183
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 128
Number of HSP's successfully gapped in prelim test: 165
Number of HSP's that attempted gapping in prelim test: 1856
Number of HSP's gapped (non-prelim): 335
length of query: 305
length of database: 18,247,518
effective HSP length: 102
effective length of query: 203
effective length of database: 14,385,186
effective search space: 2920192758
effective search space used: 2920192758
T: 11
A: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 39 (21.7 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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