Guide to the Human Genome
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Search of human proteins with 31377846

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|31377846 WD repeat domain 52 [Homo sapiens]
         (982 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31377846 WD repeat domain 52 [Homo sapiens]                       1992   0.0  
gi|223005862 echinoderm microtubule associated protein like 6 [H...   134   3e-31
gi|34485720 echinoderm microtubule associated protein like 5 [Ho...   134   4e-31
gi|223029510 echinoderm microtubule associated protein like 4 is...    87   8e-17
gi|19923497 echinoderm microtubule associated protein like 4 iso...    87   8e-17
gi|56790930 echinoderm microtubule associated protein like 1 iso...    85   3e-16
gi|6912356 echinoderm microtubule associated protein like 2 [Hom...    85   4e-16
gi|56790932 echinoderm microtubule associated protein like 1 iso...    84   6e-16
gi|94681049 hypothetical protein LOC80217 [Homo sapiens]               80   9e-15
gi|22749037 WD repeat domain 65 [Homo sapiens]                         77   8e-14
gi|190684671 mitogen-activated protein kinase binding protein 1 ...    62   2e-09
gi|190684677 mitogen-activated protein kinase binding protein 1 ...    62   2e-09
gi|110227615 echinoderm microtubule associated protein like 3 [H...    62   2e-09
gi|94400919 WD repeat domain 90 [Homo sapiens]                         62   3e-09
gi|145580608 WD repeat domain 62 isoform 1 [Homo sapiens]              57   8e-08
gi|145580610 WD repeat domain 62 isoform 2 [Homo sapiens]              57   8e-08
gi|239745093 PREDICTED: hypothetical protein XP_002343359 [Homo ...    49   2e-05
gi|17975763 myelin transcription factor 1 [Homo sapiens]               49   2e-05
gi|89886480 zinedin isoform 2 [Homo sapiens]                           48   5e-05
gi|89886477 zinedin isoform 1 [Homo sapiens]                           48   5e-05
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi...    46   1e-04
gi|55741709 RNA binding motif protein 25 [Homo sapiens]                45   3e-04
gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo sapi...    45   3e-04
gi|118600967 shroom family member 4 [Homo sapiens]                     45   3e-04
gi|28274705 family with sequence similarity 9, member A [Homo sa...    45   4e-04
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]           45   4e-04
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]           45   4e-04
gi|60498973 myelin transcription factor 1-like [Homo sapiens]          44   6e-04
gi|21071067 TBP-associated factor 5 [Homo sapiens]                     44   7e-04
gi|46276863 parathymosin [Homo sapiens]                                44   7e-04

>gi|31377846 WD repeat domain 52 [Homo sapiens]
          Length = 982

 Score = 1992 bits (5161), Expect = 0.0
 Identities = 982/982 (100%), Positives = 982/982 (100%)

Query: 1   MKEPDDQDTDGEKSVTSKSDGKKSLRSSKSESRSPVQEDNTFLEDDTDETFTKGEGSYLE 60
           MKEPDDQDTDGEKSVTSKSDGKKSLRSSKSESRSPVQEDNTFLEDDTDETFTKGEGSYLE
Sbjct: 1   MKEPDDQDTDGEKSVTSKSDGKKSLRSSKSESRSPVQEDNTFLEDDTDETFTKGEGSYLE 60

Query: 61  EDSDEERLEGSLSSFQYGDLQSTTVPQQTPAPAVEEAEEEVKKKISESFFYDYMELASMP 120
           EDSDEERLEGSLSSFQYGDLQSTTVPQQTPAPAVEEAEEEVKKKISESFFYDYMELASMP
Sbjct: 61  EDSDEERLEGSLSSFQYGDLQSTTVPQQTPAPAVEEAEEEVKKKISESFFYDYMELASMP 120

Query: 121 FVTLDSNIPLDLLTLVHSFGYDCRKRANLQLLDDSIAIYIAGNQLIFLNLKTKEQIYLRS 180
           FVTLDSNIPLDLLTLVHSFGYDCRKRANLQLLDDSIAIYIAGNQLIFLNLKTKEQIYLRS
Sbjct: 121 FVTLDSNIPLDLLTLVHSFGYDCRKRANLQLLDDSIAIYIAGNQLIFLNLKTKEQIYLRS 180

Query: 181 SSGEGIGVIGVHPHKTYFTVAEKGSFPDIIIYEYPSLRPYRVLRDGTEKGYAYVDFNYSG 240
           SSGEGIGVIGVHPHKTYFTVAEKGSFPDIIIYEYPSLRPYRVLRDGTEKGYAYVDFNYSG
Sbjct: 181 SSGEGIGVIGVHPHKTYFTVAEKGSFPDIIIYEYPSLRPYRVLRDGTEKGYAYVDFNYSG 240

Query: 241 NLLASVGSNPDYTLTIWNWKEEQPILRTKAFSQEVFKVTFNPDKEEQLTTSGSGHIKFWE 300
           NLLASVGSNPDYTLTIWNWKEEQPILRTKAFSQEVFKVTFNPDKEEQLTTSGSGHIKFWE
Sbjct: 241 NLLASVGSNPDYTLTIWNWKEEQPILRTKAFSQEVFKVTFNPDKEEQLTTSGSGHIKFWE 300

Query: 301 MAFTFTGLKLQGSLGRFGKTITTDIEGYMELPDGKVLSGSEWGNMLLWEGGLIKVELCRG 360
           MAFTFTGLKLQGSLGRFGKTITTDIEGYMELPDGKVLSGSEWGNMLLWEGGLIKVELCRG
Sbjct: 301 MAFTFTGLKLQGSLGRFGKTITTDIEGYMELPDGKVLSGSEWGNMLLWEGGLIKVELCRG 360

Query: 361 TSKSCHNGPINQIMLYEGEVITVGSDGYVRIWDFETIDTADVIDETGLLEIEPINELQVD 420
           TSKSCHNGPINQIMLYEGEVITVGSDGYVRIWDFETIDTADVIDETGLLEIEPINELQVD
Sbjct: 361 TSKSCHNGPINQIMLYEGEVITVGSDGYVRIWDFETIDTADVIDETGLLEIEPINELQVD 420

Query: 421 KNVNLFSMIKMNETGNNFWLAQDANGAIWKLDLSFSNITQDPECLFSFHSGAIEAVAVSP 480
           KNVNLFSMIKMNETGNNFWLAQDANGAIWKLDLSFSNITQDPECLFSFHSGAIEAVAVSP
Sbjct: 421 KNVNLFSMIKMNETGNNFWLAQDANGAIWKLDLSFSNITQDPECLFSFHSGAIEAVAVSP 480

Query: 481 LTYLMATTALDCSVRIYDFASKTPLAQMKFKQGGTALVWVPRMVNFTGAQIIVGFEDGVV 540
           LTYLMATTALDCSVRIYDFASKTPLAQMKFKQGGTALVWVPRMVNFTGAQIIVGFEDGVV
Sbjct: 481 LTYLMATTALDCSVRIYDFASKTPLAQMKFKQGGTALVWVPRMVNFTGAQIIVGFEDGVV 540

Query: 541 RILELYDPKGLTIFAGRKKILDADIQLKQVFKPHTACVTALAYERDGEILATGSKDQTVF 600
           RILELYDPKGLTIFAGRKKILDADIQLKQVFKPHTACVTALAYERDGEILATGSKDQTVF
Sbjct: 541 RILELYDPKGLTIFAGRKKILDADIQLKQVFKPHTACVTALAYERDGEILATGSKDQTVF 600

Query: 601 FFEVERDYKPIGYINTPGPVCQLMWSPMSHPESTLLIICENGYILEAPLPTIKQEEDDHD 660
           FFEVERDYKPIGYINTPGPVCQLMWSPMSHPESTLLIICENGYILEAPLPTIKQEEDDHD
Sbjct: 601 FFEVERDYKPIGYINTPGPVCQLMWSPMSHPESTLLIICENGYILEAPLPTIKQEEDDHD 660

Query: 661 VVSYEIKDMCIKCFHFSSVKSKILRLIEIEKRERQRELKEKIREERRNKLAAEMGEDGEK 720
           VVSYEIKDMCIKCFHFSSVKSKILRLIEIEKRERQRELKEKIREERRNKLAAEMGEDGEK
Sbjct: 661 VVSYEIKDMCIKCFHFSSVKSKILRLIEIEKRERQRELKEKIREERRNKLAAEMGEDGEK 720

Query: 721 EFQEEEEEKEEEEEEEEPLPEIFIPSTPSPILCGFYSEPGKFWVSLGGYDSGFLYHCEFP 780
           EFQEEEEEKEEEEEEEEPLPEIFIPSTPSPILCGFYSEPGKFWVSLGGYDSGFLYHCEFP
Sbjct: 721 EFQEEEEEKEEEEEEEEPLPEIFIPSTPSPILCGFYSEPGKFWVSLGGYDSGFLYHCEFP 780

Query: 781 PCDESSDFKEQKDEPIDVRYLADTEDNPIQTITFNINKVMMFCGMKNGAIRVYVLNQNDP 840
           PCDESSDFKEQKDEPIDVRYLADTEDNPIQTITFNINKVMMFCGMKNGAIRVYVLNQNDP
Sbjct: 781 PCDESSDFKEQKDEPIDVRYLADTEDNPIQTITFNINKVMMFCGMKNGAIRVYVLNQNDP 840

Query: 841 SLTSLVDYWHFNMHDNNYGCIKSIANSFDDRFLVTAGADGNIFVFNIFSEFMLRKDMKAK 900
           SLTSLVDYWHFNMHDNNYGCIKSIANSFDDRFLVTAGADGNIFVFNIFSEFMLRKDMKAK
Sbjct: 841 SLTSLVDYWHFNMHDNNYGCIKSIANSFDDRFLVTAGADGNIFVFNIFSEFMLRKDMKAK 900

Query: 901 VPSPRFGIETEPIPEDIEDPKAYSIENARRKREHDKLMKEVGEIKARKREQIKALRSEFC 960
           VPSPRFGIETEPIPEDIEDPKAYSIENARRKREHDKLMKEVGEIKARKREQIKALRSEFC
Sbjct: 901 VPSPRFGIETEPIPEDIEDPKAYSIENARRKREHDKLMKEVGEIKARKREQIKALRSEFC 960

Query: 961 NLLEMNEKLPKHMQFKRTVSLI 982
           NLLEMNEKLPKHMQFKRTVSLI
Sbjct: 961 NLLEMNEKLPKHMQFKRTVSLI 982


>gi|223005862 echinoderm microtubule associated protein like 6 [Homo
            sapiens]
          Length = 1958

 Score =  134 bits (338), Expect = 3e-31
 Identities = 132/547 (24%), Positives = 236/547 (43%), Gaps = 76/547 (13%)

Query: 118  SMPFVTLDSNIPLDLLTL--VHSF-GYDCRKRANLQLLDDSIAIY-IAGNQLIFLNLKTK 173
            ++PF+  +   P D L L  +H + GYDCR   NL        +Y IA   +++   +  
Sbjct: 663  AVPFLKREK-APEDSLKLQFIHGYRGYDCRN--NLFYTQAGEVVYHIAAVAVVYNRQQHS 719

Query: 174  EQIYLRSSSGEGIGVIGVHPHKTYFTVAEKGSFPDIIIYEYPSLRPYRVLRDGTEKGYAY 233
            +++YL     + I  + +HP K Y    + G    I +++  +L+   +L+   ++G   
Sbjct: 720  QRLYL--GHDDDILSLTIHPVKDYVATGQVGRDAAIHVWDTQTLKCLSLLKGQHQRGVCA 777

Query: 234  VDFNYSGNLLASVGSNPDYTLTIWNWKEEQPILRTKAFSQEVFKVTFNPDKEEQLTTSGS 293
            +DF+  G  L SVG +  +++  W+WK+ + I  T+    ++F V  NP   ++L T G 
Sbjct: 778  LDFSADGKCLVSVGLDDFHSIVFWDWKKGEKIATTRGHKDKIFVVKCNPHHVDKLVTVGI 837

Query: 294  GHIKFWEMA---FTFTGLKLQGSLGRFGKTITTDIEGYMELPDGKVLSGSEWGNMLLWEG 350
             HIKFW+ A   FT      +G+ G  GK  T     Y  + D  V SG+  G++ +W+ 
Sbjct: 838  KHIKFWQQAGGGFT----SKRGTFGSVGKLETMMCVSYGRMED-LVFSGAATGDIFIWKD 892

Query: 351  GLIKVELCRGTSKSCHNGPINQIMLYEGEVITVGSDGYVRIWD--FETIDTADVIDETGL 408
             L+        +   H+GP+  +   +   +T G DG V +WD  FE       I  + L
Sbjct: 893  ILLL------KTVKAHDGPVFAMYALDKGFVTGGKDGIVELWDDMFERCLKTYAIKRSAL 946

Query: 409  LEIEPINELQVDKNVNLFSMIKMNETGNNFWLAQDANGAIWKLDLSFSNITQDPECLF-- 466
                    L+ + ++   ++      G+   L    NG I ++D S       P  L   
Sbjct: 947  STSSKGLLLEDNPSIRAITL------GHGHILVGTKNGEILEIDKS------GPMTLLVQ 994

Query: 467  SFHSGAIEAVAVSPLTYLMATTALDCSVRIYDF-ASKTPLAQMKFKQGGTALVWVPRMVN 525
                G +  +A  PL  + AT + D ++RI++  A    LA  K K+GG    + P    
Sbjct: 995  GHMEGEVWGLAAHPLLPICATVSDDKTLRIWELSAQHRMLAVRKLKKGGRCCAFSP---- 1050

Query: 526  FTGAQIIVGFEDGVVRILELYDPKGLTIFAGRKKILDADIQLKQ---------------- 569
              G  + VG  DG   ++     + +  F  RK+++ +DI+  +                
Sbjct: 1051 -DGKALAVGLNDGSFLVVNADTVEDMVSFHHRKEMI-SDIKFSKDTGKYLAVASHDNFVD 1108

Query: 570  -----------VFKPHTACVTALAYERDGEILATGSKDQTVFFFEVERDYKPIGYINTPG 618
                       + K  ++ +T + ++  G++L   S  +   FFE  R  +   +I  P 
Sbjct: 1109 IYNVLTSKRVGICKGASSYITHIDWDSRGKLLQVNSGAREQLFFEAPRGKR---HIIRPS 1165

Query: 619  PVCQLMW 625
             + ++ W
Sbjct: 1166 EIEKIEW 1172



 Score =  122 bits (306), Expect = 2e-27
 Identities = 115/490 (23%), Positives = 204/490 (41%), Gaps = 82/490 (16%)

Query: 140 GYDCRKRANLQLLDDSIAIYIAGNQLIFLNLKTKEQIYLRSSSGEGIGVIGVHPHKTYFT 199
           G+ CR           +  ++AG  +++   +  ++ +L     + I  + +HP KT   
Sbjct: 21  GHQCRNNL-YYTAGKEVVYFVAGVGVVYNTREHSQKFFL--GHNDDIISLALHPDKTLVA 77

Query: 200 VAEKGSFPDIIIYEYPSLRPYRVLRDGTEKGYAYVDFNYSGNLLASVGSNPDYTLTIWNW 259
             + G  P I I++  +++   +L+D    G A + F+  G  LASVG +   T+ IW+W
Sbjct: 78  TGQVGKEPYICIWDSYNVQTVSLLKDVHTHGVACLAFDSDGQRLASVGLDAKNTVCIWDW 137

Query: 260 KEEQPILRTKAFSQEVFKVTFNPDKEEQLTTSGSGHIKFWEMAFTFTGLKLQGSLGRFGK 319
           ++ + +      S  +F ++++P +  ++ + G  HIKFW    T  G  L    G FGK
Sbjct: 138 RKGKLLASATGHSDRIFDISWDPYQPNRVVSCGVKHIKFW----TLCGNALTAKRGIFGK 193

Query: 320 TITTDIEGYMELPDGK---VLSGSEWGNMLLWEGGLIKVELCRGTSKSCHNGPINQIMLY 376
             T D++  + L   K     SG+  G++ +W+G    + L R T +  H+  I  +   
Sbjct: 194 --TGDLQTILCLACAKEDITYSGALNGDIYVWKG----LNLVR-TIQGAHSAGIFSMYAC 246

Query: 377 EGEVITVGSDGYVRIWDFETIDTADVIDETGLLEIEPINELQVDKNVNLFSMIKMNETGN 436
           E    T G DG +R+WD                + +PI ++           ++  E G 
Sbjct: 247 EEGFATGGRDGCIRLWD---------------TDFKPITKID----------LRETEQG- 280

Query: 437 NFWLAQDANGAIWKLDLSFSNITQDPE--------------CLFSFHSGAIEAVAVSPLT 482
             +         WK D   +  TQD E               L     G + A+A+ P  
Sbjct: 281 --YKGLSIRSVCWKADRLLAG-TQDSEIFEVIVRERDKPMLILQGHCEGELWALALHPKK 337

Query: 483 YLMATTALDCSVRIYDFASKTPLAQMKFKQGGTALVWVPRMVNFTGAQIIVGFEDGVVRI 542
            L  T + D SVR++  A    +A+   ++   ++ + P      G+Q+ +G +DG   +
Sbjct: 338 PLAVTGSDDRSVRLWSLADHALIARCNMEEAVRSVAFSP-----DGSQLALGMKDGSFIV 392

Query: 543 LELYDPKGLTIFAGRKKILDADIQLKQVFKPHTACVTALAYERDGEILATGSKDQTVFFF 602
           L + D   +     RK++                 +  + +  DG  LA GS D  V  +
Sbjct: 393 LRVRDMTEVVHIKDRKEV-----------------IHEMKFSPDGSYLAVGSNDGPVDVY 435

Query: 603 EVERDYKPIG 612
            V + YK IG
Sbjct: 436 AVAQRYKKIG 445



 Score =  114 bits (286), Expect = 3e-25
 Identities = 145/613 (23%), Positives = 253/613 (41%), Gaps = 86/613 (14%)

Query: 38   EDNTFLEDDTDETFTKGEGSYLEEDSDEERLEGSLSSFQYG--DLQSTTVPQQTPAPAVE 95
            +++  ++ +  +T  + +G Y  + + E+ ++ +   +     +++ T   QQ    +VE
Sbjct: 1274 QESKLVDSEESDTDVEEDGGYDSDVAREKAIDYTTKIYAVSIREMEGTKPHQQLKEVSVE 1333

Query: 96   EAEEEVKKKISESFFYDYMELASMPFVTLDSNIP-----LDLLTLVHSFGY---DCRKRA 147
            E     +  +S +        A  P     +NI      ++ L L H FGY   DCR   
Sbjct: 1334 E-----RPPVSRA--------APQPEKLQKNNITKKKKLVEELALDHVFGYRGFDCRN-- 1378

Query: 148  NLQLLDDSI-AIYIAGNQLIFLNLKTKEQ-IYLRSSSGEGIGVIGVHP-HKTYFTVAEKG 204
            NL  L+D    I+      I  NL T  Q  YL  +       +  HP ++     ++ G
Sbjct: 1379 NLHYLNDGADIIFHTAAAGIVQNLSTGSQSFYLEHTDDILCLTVNQHPKYRNVVATSQIG 1438

Query: 205  SFPDIIIYEYPSLRPYRVLRDGTEKGYAYVDFNYSGNLLASVGSNPDYTLTIWNWKEEQP 264
            + P I I++  +     +LR    KG  Y++F+ +G LL SVG +P++T+T+W W+E   
Sbjct: 1439 TTPSIHIWDAMTKHTLSMLRCFHSKGVNYINFSATGKLLVSVGVDPEHTITVWRWQEGAK 1498

Query: 265  ILRTKAFSQEVFKVTFNPDKEEQLTTSGSGHIKFWEMAFTFTGLKLQGSLGRFGKTITTD 324
            +       + +F V F PD + Q  + G  H+KFW +A +   L  +G +G  G      
Sbjct: 1499 VASRGGHLERIFVVEFRPDSDTQFVSVGVKHMKFWTLAGSAL-LYKKGVIGSLGAAKMQT 1557

Query: 325  IEGYMELPDGKVLSGSEWGNMLLWEGGLIKVELCRGTSKSCHNGPINQI--MLYEGEVIT 382
            +       +    +G+  G++ +W+       L R  +K+ H GP+  +   L +G ++T
Sbjct: 1558 MLSVAFGANNLTFTGAINGDVYVWKDHF----LIRLVAKA-HTGPVFTMYTTLRDGLIVT 1612

Query: 383  VGSD------GYVRIWDFETIDTADVIDETGLLEIEPINELQVDKNVNLFSMIKMNETGN 436
             G +      G V++WD E         ETG L +E +  +   K       I +     
Sbjct: 1613 GGKERPTKEGGAVKLWDQEMKRCRAFQLETGQL-VECVRSVCRGK-----GKILVGTKDG 1666

Query: 437  NFWLAQDANGAIWKLDLSFSNITQDPECLFSFHSGAIEAVAVSPLTYLMATTALDCSVRI 496
                  + N A        SNI  D         G I  +A  P   L  + + D + RI
Sbjct: 1667 EIIEVGEKNAA--------SNILID-----GHMEGEIWGLATHPSKDLFISASNDGTARI 1713

Query: 497  YDFASKTPLAQMKFKQGGTALVWVPRMVNFTGAQIIVGFEDGVVRILELYDPKGLTIFAG 556
            +D A K  L ++          + P      G  + +G ++G   IL +   K      G
Sbjct: 1714 WDLADKKLLNKVSLGHAARCAAYSP-----DGEMVAIGMKNGEFVILLVNSLK----VWG 1764

Query: 557  RKKILDADIQLKQVFKPHTACVTALAYERDGEILATGSKDQTVFFFEVER--DYKPIGYI 614
            +K+   + IQ              +    D   LA GS + TV F+++ +  +   IGY 
Sbjct: 1765 KKRDRKSAIQ-------------DIRISPDNRFLAVGSSEHTVDFYDLTQGTNLNRIGYC 1811

Query: 615  -NTPGPVCQLMWS 626
             + P  V Q+ +S
Sbjct: 1812 KDIPSFVIQMDFS 1824


>gi|34485720 echinoderm microtubule associated protein like 5 [Homo
            sapiens]
          Length = 1977

 Score =  134 bits (337), Expect = 4e-31
 Identities = 132/512 (25%), Positives = 223/512 (43%), Gaps = 66/512 (12%)

Query: 133  LTLVHSF-GYDCRKRANLQLLDDSIAIYIAGNQLIFLNLKTKEQIYLRSSSGEGIGVIGV 191
            L  VH + GYDCR       + + I  ++A   +I+   +  ++ YL     + I  + +
Sbjct: 679  LHFVHGYRGYDCRSNLFYTQIGE-IVYHVAAVGVIYNRQQNTQRFYL--GHDDDILCLTI 735

Query: 192  HPHKTYFTVAEKGSFPDIIIYEYPSLRPYRVLRDGTEKGYAYVDFNYSGNLLASVGSNPD 251
            HP K Y    + G  P I I++  +++P  +L+   + G + VDF+  G  LASVG +  
Sbjct: 736  HPLKDYVATGQVGRDPSIHIWDTETIKPLSILKGHHQYGVSAVDFSADGKRLASVGIDDS 795

Query: 252  YTLTIWNWKEEQPILRTKAFSQEVFKVTFNPDKEEQLTTSGSGHIKFWEMAFTFTGLKLQ 311
            +T+ +W+WK+ + +   +    ++F V  NP   ++L T+G  H+KFW  A     +  +
Sbjct: 796  HTVVLWDWKKGEKLSIARGSKDKIFVVKMNPYVPDKLITAGIKHMKFWRKAGGGL-IGRK 854

Query: 312  GSLGRFGK--TITTDIEGYMELPDGKVLSGSEWGNMLLWEGGLIKVELCRGTSKSCHNGP 369
            G +G  GK  T+   + G+ E       SG+  G++ +W       ++    +   H+GP
Sbjct: 855  GYIGTLGKNDTMMCAVYGWTE---EMAFSGTSTGDVCIWR------DIFLVKTVKAHDGP 905

Query: 370  INQIMLYEGEVITVGSDGYVRIWD--FETIDTADVIDETGLLEIEPINELQVDKNVNLFS 427
            +  +   E   +T G DG V +WD  FE       I    L        L+ + ++   S
Sbjct: 906  VFSMHALEKGFVTGGKDGIVALWDDSFERCLKTYAIKRAALAPGSKGLLLEDNPSIRAIS 965

Query: 428  MIKMNETGNNFWLAQDANGAIWKLDLSFSNITQDPECLFSFH-SGAIEAVAVSPLTYLMA 486
            +      G+   L    NG I ++D S   IT     L   H  G +  +A  P   + A
Sbjct: 966  L------GHGHILVGTKNGEILEVDKS-GPIT----LLVQGHMEGEVWGLATHPYLPICA 1014

Query: 487  TTALDCSVRIYDFA-SKTPLAQMKFKQGGTALVWVPRMVNFTGAQIIVGFEDGVVRILEL 545
            T + D ++RI+D + S   LA  K K+GG    + P      G  + VG  DG   +   
Sbjct: 1015 TVSDDKTLRIWDLSPSHCMLAVRKLKKGGRCCCFSP-----DGKALAVGLNDGSFLMANA 1069

Query: 546  YDPKGLTIFAGRKKIL------------------DADIQLKQVF--------KPHTACVT 579
               + L  F  RK ++                  D+ I +  V         K  T+ +T
Sbjct: 1070 DTLEDLVSFHHRKDMISDIRFSPGSGKYLAVASHDSFIDIYNVMSSKRVGICKGATSYIT 1129

Query: 580  ALAYERDGEILA--TGSKDQTVFFFEVERDYK 609
             + ++  G++L   TG+K+Q   FFE  R  K
Sbjct: 1130 HIDWDIRGKLLQVNTGAKEQ--LFFEAPRGKK 1159



 Score =  112 bits (279), Expect = 2e-24
 Identities = 113/477 (23%), Positives = 198/477 (41%), Gaps = 56/477 (11%)

Query: 140 GYDCRKRANLQLLDDSIAIYIAGNQLIFLNLKTKEQIYLRSSSGEGIGVIGVHPHKTYFT 199
           G+ CR         + I  ++AG  +++   + +++ Y   S  + I  + +HP +    
Sbjct: 21  GHQCRNNLYYTAAKE-IVYFVAGVGVVYSPREHRQKFYRGHS--DDIISLALHPERVLVA 77

Query: 200 VAEKGSFPDIIIYEYPSLRPYRVLRDGTEKGYAYVDFNYSGNLLASVGSNPDYTLTIWNW 259
             + G  P I I++  +++   VL+D    G A + F+  G  L SVG +    + +W+W
Sbjct: 78  TGQVGKEPYICIWDSYTVQTISVLKDVHTHGIACLAFDLDGQRLVSVGLDSKNAVCVWDW 137

Query: 260 KEEQPILRTKAFSQEVFKVTFNPDKEEQLTTSGSGHIKFWEMAFTFTGLKLQGSLGRFGK 319
           K  + +      +  +F ++++  +  +L + G  HIKFW +     G  L    G FGK
Sbjct: 138 KRGKMLSMAPGHTDRIFDISWDLYQPNKLVSCGVKHIKFWSLC----GNALTPKRGVFGK 193

Query: 320 TITTDIEGYMELP---DGKVLSGSEWGNMLLWEGGLIKVELCRGTSKSCHNGPINQIMLY 376
           T   D++  + L    D    SG+  G++ +W+G    + L R T +  H   I  +   
Sbjct: 194 T--GDLQTILCLACARDELTYSGALNGDIYVWKG----INLIR-TIQGAHAAGIFSMNAC 246

Query: 377 EGEVITVGSDGYVRIWDFETIDTADVIDETGLLEIEPINELQVDKNVNLFSMIKMNETGN 436
           E    T G DG +R+WD  T     VID             + D+     S+  +   G+
Sbjct: 247 EEGFATGGRDGCIRLWDL-TFKPITVIDLR-----------ETDQGYKGLSVRSVCWRGD 294

Query: 437 NFWLAQDANGAIWKLDLSFSNITQDPECLFSFH-SGAIEAVAVSPLTYLMATTALDCSVR 495
           +  L    +  I+++ +   N    P  +   H  G + A+AV P   L  T + D SVR
Sbjct: 295 HI-LVGTQDSEIFEIVVQERN---KPFLIMQGHCEGELWALAVHPTKPLAVTGSDDRSVR 350

Query: 496 IYDFASKTPLAQMKFKQGGTALVWVPRMVNFTGAQIIVGFEDGVVRILELYDPKGLTIFA 555
           I+       +A+   ++           VN  G  + +G +DG   +L + D   +    
Sbjct: 351 IWSLVDHALIARCNMEEPIRCAA-----VNADGIHLALGMKDGSFTVLRVRDMTEVVHIK 405

Query: 556 GRKKILDADIQLKQVFKPHTACVTALAYERDGEILATGSKDQTVFFFEVERDYKPIG 612
            RK+                  +  L Y  DG  LA G  D +V  + V + YK +G
Sbjct: 406 DRKE-----------------AIHELKYSPDGTYLAVGCNDSSVDIYGVAQRYKKVG 445



 Score =  105 bits (261), Expect = 3e-22
 Identities = 115/501 (22%), Positives = 200/501 (39%), Gaps = 78/501 (15%)

Query: 129  PLDLLTLVHSFGY---DCRKRANLQLLDDSIAIYIAGNQLIFLNLKTKEQIYLRSSSGEG 185
            P++ L L   FGY   DCR   +  L D    IY   +  I  N+ T  Q + +  + + 
Sbjct: 1367 PIEDLVLELIFGYRGRDCRNNVHY-LNDGDDIIYHTASVGILHNVATGSQSFYQEHNDD- 1424

Query: 186  IGVIGVHPHKTYFTVAEKGSF----------PDIIIYEYPSLRPYRVLRDGTEKGYAYVD 235
            I  + V+ H  +  +   G            P I I++  + +   +LR    KG   V 
Sbjct: 1425 ILCLTVNQHPKFINIVATGQVGDSADMSATAPSIHIWDAMNKQTLSILRCYHSKGVCSVS 1484

Query: 236  FNYSGNLLASVGSNPDYTLTIWNWKEEQPILRTKAFSQEVFKVTFNPDKEEQLTTSGSGH 295
            F+ +G LL SVG +P++T+TIW W+E   I      +Q +F   F PD + Q  + G  H
Sbjct: 1485 FSATGKLLLSVGLDPEHTITIWRWQEGAKIASRAGHNQRIFVAEFRPDSDTQFVSVGVKH 1544

Query: 296  IKFWEMAFTFTGLKLQGSLGRFGKTITTDIEGYMELPDGK---VLSGSEWGNMLLWEGGL 352
            +KFW    T  G  L    G         ++  + +  G      +G+  G++ +W+  +
Sbjct: 1545 VKFW----TLAGRALLSKKGLLSTLEDARMQTMLAIAFGANNLTFTGTISGDVCVWKDHI 1600

Query: 353  IKVELCRGTSKSCHNGPINQI--MLYEGEVITVGSD------GYVRIWDFETIDTADVID 404
                LCR  +++ HNGP+  +   L +G ++T G +      G V++WD E         
Sbjct: 1601 ----LCRIVARA-HNGPVFAMYTTLRDGLIVTGGKERPSKEGGAVKLWDQELRRCRAFRL 1655

Query: 405  ETGLLEIEPINELQVDKNVNLFSMIKMNETGNNFWLAQDANGAIWKLDLSFSNITQDPEC 464
            ETG                     ++    G    L    N  I  +++   N   +   
Sbjct: 1656 ETG----------------QATDCVRSVCRGKGKILVGTRNAEI--IEVGEKNAACN--I 1695

Query: 465  LFSFH-SGAIEAVAVSPLTYLMATTALDCSVRIYDFASKTPLAQMKFKQGGTALVWVPRM 523
            L + H  G I  +A  P      + A D +VR++D A K  L ++        + + P  
Sbjct: 1696 LVNGHVDGPIWGLATHPSRDFFLSAAEDGTVRLWDIADKKMLNKVNLGHAARTVCYSPE- 1754

Query: 524  VNFTGAQIIVGFEDGVVRILELYDPKGLTIFAGRKKILDADIQLKQVFKPHTACVTALAY 583
                G  + +G ++G   IL                 L + +++    +     +  + +
Sbjct: 1755 ----GDMVAIGMKNGEFIIL-----------------LVSSLKIWGKKRDRRCAIHDIRF 1793

Query: 584  ERDGEILATGSKDQTVFFFEV 604
              D   LA GS + +V F+++
Sbjct: 1794 SPDSRYLAVGSSENSVDFYDL 1814


>gi|223029510 echinoderm microtubule associated protein like 4
           isoform b [Homo sapiens]
          Length = 923

 Score = 87.0 bits (214), Expect = 8e-17
 Identities = 123/578 (21%), Positives = 220/578 (38%), Gaps = 108/578 (18%)

Query: 126 SNIPLDLLTLVHSFGY---DCRKRANLQLLDDSIAIYIAGNQLIFLNLKTKEQIYLRSSS 182
           + +P + L L  ++GY   DCR  AN+ LL     +Y   + ++  N + + Q +    +
Sbjct: 194 TELPPEKLKLEWAYGYRGKDCR--ANVYLLPTGEIVYFIASVVVLFNYEERTQRHYLGHT 251

Query: 183 GEGIGVIGVHPHKTYFTVAEKGSF--------PDIIIYEYPSLRPYRVLRDGT-EKGYAY 233
            + +  + +HP K      +            P + +++  +L   +++  GT E+G   
Sbjct: 252 -DCVKCLAIHPDKIRIATGQIAGVDKDGRPLQPHVRVWDSVTLSTLQIIGLGTFERGVGC 310

Query: 234 VDFNY--SGNLLASVGSNPDYTLTIWNWKEEQPILRTKAFSQEVFKVTFNPDKEEQLTTS 291
           +DF+   SG  L  +  + ++ LT+W+W+++      K  ++ V  V F+P     + T 
Sbjct: 311 LDFSKADSGVHLCVIDDSNEHMLTVWDWQKKAKGAEIKTTNEVVLAVEFHPTDANTIITC 370

Query: 292 GSGHIKFWEMAFTFTGLKLQGSLGRFGKTITTD-IEGYMELPDGKVLSGSEWGNMLLWEG 350
           G  HI FW    T++G  L    G FGK      ++    L +G VL+G   G ML+W  
Sbjct: 371 GKSHIFFW----TWSGNSLTRKQGIFGKYEKPKFVQCLAFLGNGDVLTGDSGGVMLIW-- 424

Query: 351 GLIKVELCRGTSKSCHNGPINQIMLYEGEVITV------------GSDGYVRIWDFETID 398
               VE   G           QI  ++G V T+            G D  + +WD +   
Sbjct: 425 SKTTVEPTPGKGPKGVYQISKQIKAHDGSVFTLCQMRNGMLLTGGGKDRKIILWDHDLNP 484

Query: 399 TADVIDETGLLEIEPINELQVDKNVNLFSMIKMNETGNNFWLAQDANGAIWKLDLSFSNI 458
             ++        I  + E + D+         +  T  NF L    N             
Sbjct: 485 EREIEVPDQYGTIRAVAEGKADQ--------FLVGTSRNFILRGTFNDGF---------- 526

Query: 459 TQDPECLFSFHSGAIEAVAVSPLTYLMATTALDCSVRIYDFASKTPLAQMKFKQGGTALV 518
               +     H+  +  +A  P   L+ T A D  V +++         M+ +   T LV
Sbjct: 527 ----QIEVQGHTDELWGLATHPFKDLLLTCAQDRQVCLWN--------SMEHRLEWTRLV 574

Query: 519 WVP-RMVNFTGAQIIVGFEDGVVRILELYDPKGLTIFAGRKKILDADIQ-LKQVFKPHTA 576
             P    +F  +  +V                 +   +GR  +LDA+ + L  +      
Sbjct: 575 DEPGHCADFHPSGTVV----------------AIGTHSGRWFVLDAETRDLVSIHTDGNE 618

Query: 577 CVTALAYERDGEILATGSKDQTVFFFEVE---RDYKPIGYINTPGP-VCQLMWSPMSHPE 632
            ++ + Y  DG  LA GS D  ++ + V    R Y   G        +  L WSP     
Sbjct: 619 QLSVMRYSIDGTFLAVGSHDNFIYLYVVSENGRKYSRYGRCTGHSSYITHLDWSP----- 673

Query: 633 STLLIICENGYILEAPLPTIKQEEDDHDVVSYEIKDMC 670
                  +N YI+            D++++ ++I + C
Sbjct: 674 -------DNKYIM--------SNSGDYEILYWDIPNGC 696


>gi|19923497 echinoderm microtubule associated protein like 4
           isoform a [Homo sapiens]
          Length = 981

 Score = 87.0 bits (214), Expect = 8e-17
 Identities = 123/578 (21%), Positives = 220/578 (38%), Gaps = 108/578 (18%)

Query: 126 SNIPLDLLTLVHSFGY---DCRKRANLQLLDDSIAIYIAGNQLIFLNLKTKEQIYLRSSS 182
           + +P + L L  ++GY   DCR  AN+ LL     +Y   + ++  N + + Q +    +
Sbjct: 252 TELPPEKLKLEWAYGYRGKDCR--ANVYLLPTGEIVYFIASVVVLFNYEERTQRHYLGHT 309

Query: 183 GEGIGVIGVHPHKTYFTVAEKGSF--------PDIIIYEYPSLRPYRVLRDGT-EKGYAY 233
            + +  + +HP K      +            P + +++  +L   +++  GT E+G   
Sbjct: 310 -DCVKCLAIHPDKIRIATGQIAGVDKDGRPLQPHVRVWDSVTLSTLQIIGLGTFERGVGC 368

Query: 234 VDFNY--SGNLLASVGSNPDYTLTIWNWKEEQPILRTKAFSQEVFKVTFNPDKEEQLTTS 291
           +DF+   SG  L  +  + ++ LT+W+W+++      K  ++ V  V F+P     + T 
Sbjct: 369 LDFSKADSGVHLCVIDDSNEHMLTVWDWQKKAKGAEIKTTNEVVLAVEFHPTDANTIITC 428

Query: 292 GSGHIKFWEMAFTFTGLKLQGSLGRFGKTITTD-IEGYMELPDGKVLSGSEWGNMLLWEG 350
           G  HI FW    T++G  L    G FGK      ++    L +G VL+G   G ML+W  
Sbjct: 429 GKSHIFFW----TWSGNSLTRKQGIFGKYEKPKFVQCLAFLGNGDVLTGDSGGVMLIW-- 482

Query: 351 GLIKVELCRGTSKSCHNGPINQIMLYEGEVITV------------GSDGYVRIWDFETID 398
               VE   G           QI  ++G V T+            G D  + +WD +   
Sbjct: 483 SKTTVEPTPGKGPKGVYQISKQIKAHDGSVFTLCQMRNGMLLTGGGKDRKIILWDHDLNP 542

Query: 399 TADVIDETGLLEIEPINELQVDKNVNLFSMIKMNETGNNFWLAQDANGAIWKLDLSFSNI 458
             ++        I  + E + D+         +  T  NF L    N             
Sbjct: 543 EREIEVPDQYGTIRAVAEGKADQ--------FLVGTSRNFILRGTFNDGF---------- 584

Query: 459 TQDPECLFSFHSGAIEAVAVSPLTYLMATTALDCSVRIYDFASKTPLAQMKFKQGGTALV 518
               +     H+  +  +A  P   L+ T A D  V +++         M+ +   T LV
Sbjct: 585 ----QIEVQGHTDELWGLATHPFKDLLLTCAQDRQVCLWN--------SMEHRLEWTRLV 632

Query: 519 WVP-RMVNFTGAQIIVGFEDGVVRILELYDPKGLTIFAGRKKILDADIQ-LKQVFKPHTA 576
             P    +F  +  +V                 +   +GR  +LDA+ + L  +      
Sbjct: 633 DEPGHCADFHPSGTVV----------------AIGTHSGRWFVLDAETRDLVSIHTDGNE 676

Query: 577 CVTALAYERDGEILATGSKDQTVFFFEVE---RDYKPIGYINTPGP-VCQLMWSPMSHPE 632
            ++ + Y  DG  LA GS D  ++ + V    R Y   G        +  L WSP     
Sbjct: 677 QLSVMRYSIDGTFLAVGSHDNFIYLYVVSENGRKYSRYGRCTGHSSYITHLDWSP----- 731

Query: 633 STLLIICENGYILEAPLPTIKQEEDDHDVVSYEIKDMC 670
                  +N YI+            D++++ ++I + C
Sbjct: 732 -------DNKYIM--------SNSGDYEILYWDIPNGC 754


>gi|56790930 echinoderm microtubule associated protein like 1
           isoform b [Homo sapiens]
          Length = 815

 Score = 85.1 bits (209), Expect = 3e-16
 Identities = 124/609 (20%), Positives = 229/609 (37%), Gaps = 85/609 (13%)

Query: 29  KSESRSPVQEDNTFLEDDTDETFTKGEGSYLEEDSDEERLEGSLSSFQYGDLQSTTVPQQ 88
           + E+  P  + N      ++     G      +        GS SS   G   S + P++
Sbjct: 118 RKETAVPATKSNIKRTSSSERVSPGGRRESNGDSRGNRNRTGSTSSSSSGKKNSESKPKE 177

Query: 89  TPAPAVEEAEEEVKKKISESFFYDYMELASMPFVTLDSNI--PLDLLTLVHSFGY---DC 143
              P     E  VK  +       YM    +   +L++ +  P   L L   +GY   DC
Sbjct: 178 ---PVFSAEEGYVKMFLRGRPVTMYMPKDQVDSYSLEAKVELPTKRLKLEWVYGYRGRDC 234

Query: 144 RKRANLQLLDDSIAIYIAGNQLIFLNLKTKEQIYLRSSSGEGIGVIGVHPHKTYFTVAE- 202
           R   NL LL     +Y   + ++  N++ + Q +  +   + +  + VHP +      + 
Sbjct: 235 RN--NLYLLPTGETVYFIASVVVLYNVEEQLQRHY-AGHNDDVKCLAVHPDRITIATGQV 291

Query: 203 -------KGSFPDIIIYEYPSLRPYRVLRDGT-EKGYAYVDFNYS--GNLLASVGSNPDY 252
                  K   P + I++  +L    V+  G  ++    + F+ S  G  L +V  + D+
Sbjct: 292 AGTSKDGKQLPPHVRIWDSVTLNTLHVIGIGFFDRAVTCIAFSKSNGGTNLCAVDDSNDH 351

Query: 253 TLTIWNWKEEQPILRTKAFSQEVFKVTFNPDKEEQLTTSGSGHIKFWEMAFTFTGLKLQG 312
            L++W+W++E+ +   K  ++ VF   F+P     + T G  H+ FW    T  G  L  
Sbjct: 352 VLSVWDWQKEEKLADVKCSNEAVFAADFHPTDTNIIVTCGKSHLYFW----TLEGSSLNK 407

Query: 313 SLGRFGKTITTDIEGYMELPD-GKVLSGSEWGNMLLWEGGLIKVELCRGTSKSCHNGPIN 371
             G F K         +   + G  ++G   GN+L+W  G  ++       +  H G I 
Sbjct: 408 KQGLFEKQEKPKFVLCVTFSENGDTITGDSSGNILVWGKGTNRISY---AVQGAHEGGIF 464

Query: 372 QI-MLYEGEVIT-VGSDGYVRIW--DFETIDTADVIDETGLLEIEPINELQVDKNVNLFS 427
            + ML +G +++  G D  +  W  +++ +   ++ ++ G     PI  +   K      
Sbjct: 465 ALCMLRDGTLVSGGGKDRKLISWSGNYQKLRKTEIPEQFG-----PIRTVAEGK-----G 514

Query: 428 MIKMNETGNNFWLAQDANGAIWKLDLSFSNITQDPECLFSFHSGAIEAVAVSPLTYLMAT 487
            + +  T  NF L    +G        F+ ITQ        H+  +  +A+        T
Sbjct: 515 DVILIGTTRNFVLQGTLSG-------DFTPITQG-------HTDELWGLAIHASKSQFLT 560

Query: 488 TALDCSVRIYDFASKTPLAQMKFKQGGTALVWVPRMVNFTGAQIIVGFEDGVVRILELYD 547
              D    ++D     P+     +    +  + P     +G+ + VG             
Sbjct: 561 CGHDKHATLWDAVGHRPVWDKIIEDPAQSSGFHP-----SGSVVAVG------------- 602

Query: 548 PKGLTIFAGRKKILDADIQ-LKQVFKPHTACVTALAYERDGEILATGSKDQTVFFFEVE- 605
                   GR  + D + + L  V       ++ + Y  DG  LA GS D  ++ + V  
Sbjct: 603 -----TLTGRWFVFDTETKDLVTVHTDGNEQLSVMRYSPDGNFLAIGSHDNCIYIYGVSD 657

Query: 606 --RDYKPIG 612
             R Y  +G
Sbjct: 658 NGRKYTRVG 666


>gi|6912356 echinoderm microtubule associated protein like 2 [Homo
           sapiens]
          Length = 649

 Score = 84.7 bits (208), Expect = 4e-16
 Identities = 125/543 (23%), Positives = 213/543 (39%), Gaps = 99/543 (18%)

Query: 115 ELASMPFVTLDSNIPLDLLTLVHSFGY---DCRKRANLQLLDDSIAIYIAGNQLIFLNLK 171
           ELA    +   S +P   L L   +GY   DCR  ANL LL     +Y   +  +  +++
Sbjct: 37  ELAPTYSLDTRSELPSCRLKLEWVYGYRGRDCR--ANLYLLPTGEIVYFVASVAVLYSVE 94

Query: 172 TKEQIYLRSSSGEGIGVIGVHPHKTYFTVAE--------KGSFPDIIIYEYPSLRPYRVL 223
            + Q +    + + I  + +HP        +        K   P + I++  SL    VL
Sbjct: 95  EQRQRHYLGHNDD-IKCLAIHPDMVTIATGQVAGTTKEGKPLPPHVRIWDSVSLSTLHVL 153

Query: 224 RDGT-EKGYAYVDFNYS--GNLLASVGSNPDYTLTIWNWKEEQPILRTKAFSQEVFKVTF 280
             G  ++    V F+ S  GNLL +V  + D+ L++W+W +E  ++  K  ++ V   TF
Sbjct: 154 GLGVFDRAVCCVGFSKSNGGNLLCAVDESNDHMLSVWDWAKETKVVDVKCSNEAVLVATF 213

Query: 281 NPDKEEQLTTSGSGHIKFWEMAFTFTGLKLQGSLGRFGK-------TITTDIEGYMELPD 333
           +P     L T G  HI FW    T  G  L    G F K          T +EG      
Sbjct: 214 HPTDPTVLITCGKSHIYFW----TLEGGSLSKRQGLFEKHEKPKYVLCVTFLEG------ 263

Query: 334 GKVLSGSEWGNMLLW-EGGLIKVELCRGTSKSCHNGPI-NQIMLYEGEVITVGS-DGYVR 390
           G V++G   GN+ +W +GG    +   G     H+G +     L +G +++ G  D  V 
Sbjct: 264 GDVVTGDSGGNLYVWGKGGNRITQAVLG----AHDGGVFGLCALRDGTLVSGGGRDRRVV 319

Query: 391 IW--DFETIDTADVIDETG-----------LLEIEPINELQVDKNVNL-FSMIKMNETGN 436
           +W  D+  +   +V ++ G            L +       +  +V+  FS++       
Sbjct: 320 LWGSDYSKLQEVEVPEDFGPVRTVAEGHGDTLYVGTTRNSILQGSVHTGFSLLVQGHVEE 379

Query: 437 NFWLA------------QDANGAIWKLDLS---FSNITQDPECLFSFH-SGAIEAVAVSP 480
            + LA            QD    +W  D     +S I +DP     FH SG++ AV    
Sbjct: 380 LWGLATHPSRAQFVTCGQDKLVHLWSSDSHQPLWSRIIEDPARSAGFHPSGSVLAVGTVT 439

Query: 481 LTYLMATTALDCSVRIYDFASKTPLAQMKFKQGGTALVWVPRMVNFTGAQIIVGFEDGVV 540
             +L+  T     V I+   ++  ++ + F                 GA + VG  D +V
Sbjct: 440 GRWLLLDTETHDLVAIHTDGNE-QISVVSFSP--------------DGAYLAVGSHDNLV 484

Query: 541 RILELYDPKGLTIFAGRKKILDADIQLKQVFKPHTACVTALAYERDGEILATGSKDQTVF 600
            +         T+  G +K     +        H++ +T L + +D     T S D  + 
Sbjct: 485 YV--------YTVDQGGRK-----VSRLGKCSGHSSFITHLDWAQDSSCFVTNSGDYEIL 531

Query: 601 FFE 603
           +++
Sbjct: 532 YWD 534


>gi|56790932 echinoderm microtubule associated protein like 1
           isoform a [Homo sapiens]
          Length = 834

 Score = 84.0 bits (206), Expect = 6e-16
 Identities = 120/568 (21%), Positives = 219/568 (38%), Gaps = 85/568 (14%)

Query: 70  GSLSSFQYGDLQSTTVPQQTPAPAVEEAEEEVKKKISESFFYDYMELASMPFVTLDSNI- 128
           GS SS   G   S + P++   P     E  VK  +       YM    +   +L++ + 
Sbjct: 178 GSTSSSSSGKKNSESKPKE---PVFSAEEGYVKMFLRGRPVTMYMPKDQVDSYSLEAKVE 234

Query: 129 -PLDLLTLVHSFGY---DCRKRANLQLLDDSIAIYIAGNQLIFLNLKTKEQIYLRSSSGE 184
            P   L L   +GY   DCR   NL LL     +Y   + ++  N++ + Q +  +   +
Sbjct: 235 LPTKRLKLEWVYGYRGRDCRN--NLYLLPTGETVYFIASVVVLYNVEEQLQRHY-AGHND 291

Query: 185 GIGVIGVHPHKTYFTVAE--------KGSFPDIIIYEYPSLRPYRVLRDGT-EKGYAYVD 235
            +  + VHP +      +        K   P + I++  +L    V+  G  ++    + 
Sbjct: 292 DVKCLAVHPDRITIATGQVAGTSKDGKQLPPHVRIWDSVTLNTLHVIGIGFFDRAVTCIA 351

Query: 236 FNYS--GNLLASVGSNPDYTLTIWNWKEEQPILRTKAFSQEVFKVTFNPDKEEQLTTSGS 293
           F+ S  G  L +V  + D+ L++W+W++E+ +   K  ++ VF   F+P     + T G 
Sbjct: 352 FSKSNGGTNLCAVDDSNDHVLSVWDWQKEEKLADVKCSNEAVFAADFHPTDTNIIVTCGK 411

Query: 294 GHIKFWEMAFTFTGLKLQGSLGRFGKTITTDIEGYMELPD-GKVLSGSEWGNMLLWEGGL 352
            H+ FW    T  G  L    G F K         +   + G  ++G   GN+L+W  G 
Sbjct: 412 SHLYFW----TLEGSSLNKKQGLFEKQEKPKFVLCVTFSENGDTITGDSSGNILVWGKGT 467

Query: 353 IKVELCRGTSKSCHNGPINQI-MLYEGEVIT-VGSDGYVRIW--DFETIDTADVIDETGL 408
            ++       +  H G I  + ML +G +++  G D  +  W  +++ +   ++ ++ G 
Sbjct: 468 NRISY---AVQGAHEGGIFALCMLRDGTLVSGGGKDRKLISWSGNYQKLRKTEIPEQFG- 523

Query: 409 LEIEPINELQVDKNVNLFSMIKMNETGNNFWLAQDANGAIWKLDLSFSNITQDPECLFSF 468
               PI  +   K       + +  T  NF L    +G        F+ ITQ        
Sbjct: 524 ----PIRTVAEGK-----GDVILIGTTRNFVLQGTLSG-------DFTPITQG------- 560

Query: 469 HSGAIEAVAVSPLTYLMATTALDCSVRIYDFASKTPLAQMKFKQGGTALVWVPRMVNFTG 528
           H+  +  +A+        T   D    ++D     P+     +    +  + P     +G
Sbjct: 561 HTDELWGLAIHASKSQFLTCGHDKHATLWDAVGHRPVWDKIIEDPAQSSGFHP-----SG 615

Query: 529 AQIIVGFEDGVVRILELYDPKGLTIFAGRKKILDADIQ-LKQVFKPHTACVTALAYERDG 587
           + + VG                     GR  + D + + L  V       ++ + Y  DG
Sbjct: 616 SVVAVG------------------TLTGRWFVFDTETKDLVTVHTDGNEQLSVMRYSPDG 657

Query: 588 EILATGSKDQTVFFFEVE---RDYKPIG 612
             LA GS D  ++ + V    R Y  +G
Sbjct: 658 NFLAIGSHDNCIYIYGVSDNGRKYTRVG 685


>gi|94681049 hypothetical protein LOC80217 [Homo sapiens]
          Length = 1665

 Score = 80.1 bits (196), Expect = 9e-15
 Identities = 42/154 (27%), Positives = 77/154 (50%), Gaps = 1/154 (0%)

Query: 146 RANLQLLDDSIAIYIAGNQLIFLNLKTKEQIYLRSSSGEGIGVIGVHPHKTYFTVAEKGS 205
           + N+  ++D+   Y  GN +IF+N++TK++  L+ S+G  +GV+  +        +++  
Sbjct: 29  KQNVHFVNDNTICYPCGNYVIFINIETKKKTVLQCSNGI-VGVMATNIPCEVVAFSDRKL 87

Query: 206 FPDIIIYEYPSLRPYRVLRDGTEKGYAYVDFNYSGNLLASVGSNPDYTLTIWNWKEEQPI 265
            P I +Y +P L     L+      Y  + F+Y G  LAS  S P++ L +WNW+    +
Sbjct: 88  KPLIYVYSFPGLTRRTKLKGNILLDYTLLSFSYCGTYLASYSSLPEFELALWNWESSIIL 147

Query: 266 LRTKAFSQEVFKVTFNPDKEEQLTTSGSGHIKFW 299
            +      +V +++FNP    QL  S    +  W
Sbjct: 148 CKKSQPGMDVNQMSFNPMNWRQLCLSSPSTVSVW 181



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 29/80 (36%), Positives = 41/80 (51%), Gaps = 6/80 (7%)

Query: 663 SYEIKDMCIKCFHFSSVKSKI---LRLIEIEKRERQRELKEKIREERRNKLAAEMGE--D 717
           S  +K   +KCFH   V        R +E E +E +R L++K  E    KL  E+ E   
Sbjct: 888 SMAVKGRALKCFHIPCVVENFPMKARTVE-ELKELERVLQQKKIEAECLKLRKEIVEAQS 946

Query: 718 GEKEFQEEEEEKEEEEEEEE 737
           G K  ++  EE +EEEEEE+
Sbjct: 947 GVKLIKQRHEEDDEEEEEED 966


>gi|22749037 WD repeat domain 65 [Homo sapiens]
          Length = 698

 Score = 77.0 bits (188), Expect = 8e-14
 Identities = 114/545 (20%), Positives = 222/545 (40%), Gaps = 96/545 (17%)

Query: 136 VHSFGYDCRKRANLQLLDDSIAIYIAGNQLIFLNLKTKEQIYLRSSS-GEGIGVIGVHPH 194
           +H FG       N+   D+ I I+ +GN  +  N+  K Q ++  S   +G+  + + P+
Sbjct: 9   LHVFGLRSHVANNIFYFDEQIIIFPSGNHCVKYNVDQKWQKFIPGSEKSQGMLALSISPN 68

Query: 195 KTYFTVAEK-GSFPDIIIYEYPSL--RPYRVLR--DGTEKGYAYVDFNYSGNLLASVGSN 249
           + Y  ++E     P I IYE  S+  R  +VL   D   + +  + F+     L +  S 
Sbjct: 69  RRYLAISETVQEKPAITIYELSSIPCRKRKVLNNFDFQVQKFISMAFSPDSKYLLAQTSP 128

Query: 250 PDYTLTIWNWKEEQ--PILRTKAFSQEVFKVTFNPDKEEQLTTSGSGHIKFWEMAFTFTG 307
           P+  L  W W++++   I+R    +  V++V+F+P    Q+  +G+G  K    A     
Sbjct: 129 PESNLVYWLWEKQKVMAIVRIDTQNNPVYQVSFSPQDNTQVCVTGNGMFKLLRFA----- 183

Query: 308 LKLQGSLGR--FGKTITTDIEGYMELPDGKVLSGSEWGNMLLWEGG------LIKVELCR 359
              +G+L +  F +    +   +  + D K++ G++ G + L+E G       I V+   
Sbjct: 184 ---EGTLKQTSFQRGEPQNYLAHTWVADDKIVVGTDTGKLFLFESGDQRWETSIMVKEPT 240

Query: 360 GTSKSCH--------------NGPI------------NQIMLYEGEVITVGSDGYV---- 389
             SKS                + P+            +Q+ + +   I   S G+     
Sbjct: 241 NGSKSLDVIQESESLIEFPPVSSPLPSYEQMVAASSHSQMSMPQVFAIAAYSKGFACSAG 300

Query: 390 --RIWDFETIDTADVIDETGLLEI----EPINELQVDKNVNLFSMIKMNETGNNFWLAQD 443
             R+  FE ++  D   E+  + I    +  +  Q DK   L      +E      +A  
Sbjct: 301 PGRVLLFEKMEEKDFYRESREIRIPVDPQSNDPSQSDKQDVLCLCFSPSE---ETLVAST 357

Query: 444 ANGAIWKLDLSFSNITQDPECLFSF-----HSGAIEAVAVSPLTYLMATTALDCSVRIYD 498
           +   ++ + +S + I++     F +     HS  I  +A      L+AT +LD S+R+++
Sbjct: 358 SKNQLYSITMSLTEISKGEPAHFEYLMYPLHSAPITGLATCIRKPLIATCSLDRSIRLWN 417

Query: 499 FASKTPLAQMKFKQGGTALVWVPRMVNFTGAQIIVGFEDGV---------VRILELYDPK 549
           + + T     ++++   ++   P     +G  I+VGF D +         +R  + Y  +
Sbjct: 418 YETNTLELFKEYQEEAYSISLHP-----SGHFIVVGFADKLRLMNLLIDDIRSFKEYSVR 472

Query: 550 GL---------TIFA---GRKKILDADIQLKQV--FKPHTACVTALAYERDGEILATGSK 595
           G           +FA   G    +     L+ +   K HT  + ++ +  D   L +G  
Sbjct: 473 GCGECSFSNGGHLFAAVNGNVIHVYTTTSLENISSLKGHTGKIRSIVWNADDSKLISGGT 532

Query: 596 DQTVF 600
           D  V+
Sbjct: 533 DGAVY 537


>gi|190684671 mitogen-activated protein kinase binding protein 1
           isoform a [Homo sapiens]
          Length = 1508

 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 46/178 (25%), Positives = 77/178 (43%), Gaps = 11/178 (6%)

Query: 156 IAIYIAGNQLIFLNLKTKEQIYLRSSSGEGIGVIGVHPHKTYFTVAEKGSFPDIIIYEYP 215
           +  Y AG  ++  N +  +Q ++ +SS + I  +   P   Y    E G  P + +++  
Sbjct: 63  LVAYPAGCVVVLFNPRKHKQHHILNSSRKTITALAFSPDGKYLVTGESGHMPAVRVWDVA 122

Query: 216 SLRPYRVLRDGTEKGYAYVDFNYSGNLLASVGSNPDYTLTIWNWKEEQPILRTKAFSQEV 275
                  L++  + G A V F+ S   + SVG   D  + +W WK+   +   K  S  V
Sbjct: 123 EHSQVAELQEH-KYGVACVAFSPSAKYIVSVGYQHDMIVNVWAWKKNIVVASNKV-SSRV 180

Query: 276 FKVTFNPDKEEQLTTSGSGHIKFWEMAFTFTG--------LKLQGSLGRFGKTITTDI 325
             V+F+ D      T+G+ HIKFW +  + T         L   G LG     + TD+
Sbjct: 181 TAVSFSEDC-SYFVTAGNRHIKFWYLDDSKTSKVNATVPLLGRSGLLGELRNNLFTDV 237


>gi|190684677 mitogen-activated protein kinase binding protein 1
           isoform b [Homo sapiens]
          Length = 1514

 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 46/178 (25%), Positives = 77/178 (43%), Gaps = 11/178 (6%)

Query: 156 IAIYIAGNQLIFLNLKTKEQIYLRSSSGEGIGVIGVHPHKTYFTVAEKGSFPDIIIYEYP 215
           +  Y AG  ++  N +  +Q ++ +SS + I  +   P   Y    E G  P + +++  
Sbjct: 63  LVAYPAGCVVVLFNPRKHKQHHILNSSRKTITALAFSPDGKYLVTGESGHMPAVRVWDVA 122

Query: 216 SLRPYRVLRDGTEKGYAYVDFNYSGNLLASVGSNPDYTLTIWNWKEEQPILRTKAFSQEV 275
                  L++  + G A V F+ S   + SVG   D  + +W WK+   +   K  S  V
Sbjct: 123 EHSQVAELQEH-KYGVACVAFSPSAKYIVSVGYQHDMIVNVWAWKKNIVVASNKV-SSRV 180

Query: 276 FKVTFNPDKEEQLTTSGSGHIKFWEMAFTFTG--------LKLQGSLGRFGKTITTDI 325
             V+F+ D      T+G+ HIKFW +  + T         L   G LG     + TD+
Sbjct: 181 TAVSFSEDC-SYFVTAGNRHIKFWYLDDSKTSKVNATVPLLGRSGLLGELRNNLFTDV 237


>gi|110227615 echinoderm microtubule associated protein like 3 [Homo
           sapiens]
          Length = 896

 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 88/393 (22%), Positives = 156/393 (39%), Gaps = 52/393 (13%)

Query: 228 EKGYAYVDFNYS--GNLLASVGSNPDYTLTIWNWKEEQPILRTKAFSQEVFKVTFNPDKE 285
           E+G   + F+ +  G  L  V  + ++ L++W+      +   K+ +  V  V FNP   
Sbjct: 359 ERGVGALAFSAADQGAFLCVVDDSNEHMLSVWDCSRGMKLAEIKSTNDSVLAVGFNPRDS 418

Query: 286 EQLTTSGSGHIKFWE------MAFTFTGLKLQGSLGRFGKTITTDIEGYMELPDGKVLSG 339
             + TSG  H+ FW       +    T  + QG  G++ K     I  ++ LPDG +L+G
Sbjct: 419 SCIVTSGKSHVHFWNWSGGVGVPGNGTLTRKQGVFGKYKK--PKFIPCFVFLPDGDILTG 476

Query: 340 SEWGNMLLWEGGLIKVEL-CRGTSKSCHNGPINQIMLYEGEV--ITVGSDGYVRIWDFET 396
              GN+L W       +   RG +K  + G + Q   +EG +  + +  DG V       
Sbjct: 477 DSEGNILTWGRSPSDSKTPGRGGAKETY-GIVAQAHAHEGSIFALCLRRDGTVLSGGGR- 534

Query: 397 IDTADVIDETGLLEIEPINELQVDKNVNLFSMIKMNETGNNFWLAQDANGAIWKLDLS-- 454
            D   V    GL+ ++   E ++ ++      I   E   +  L      A+ + DL+  
Sbjct: 535 -DRRLVQWGPGLVALQ---EAEIPEHFGAVRAIA--EGLGSELLVGTTKNALLRGDLAQG 588

Query: 455 FSNITQDPECLFSFHSGAIEAVAVSPLTYLMATTALDCSVRIYDFASKTPLAQMKFKQGG 514
           FS + Q        H+  +  +   P      T   D  + ++D  S      +  K+ G
Sbjct: 589 FSPVIQG-------HTDELWGLCTHPSQNRFLTCGHDRQLCLWDGESHALAWSIDLKETG 641

Query: 515 TALVWVPRMVNFTGAQIIVGFEDGVVRILELYDPKGLTIFAGRKKILDADIQLKQVFKPH 574
               + P     +GA + VG   G   +L+    + ++       ++D + QL       
Sbjct: 642 LCADFHP-----SGAVVAVGLNTGRWLVLDTETREIVS------DVIDGNEQL------- 683

Query: 575 TACVTALAYERDGEILATGSKDQTVFFFEVERD 607
               + + Y  DG  LA GS D  ++ + V  D
Sbjct: 684 ----SVVRYSPDGLYLAIGSHDNVIYIYSVSSD 712


>gi|94400919 WD repeat domain 90 [Homo sapiens]
          Length = 1748

 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 79/367 (21%), Positives = 138/367 (37%), Gaps = 34/367 (9%)

Query: 236  FNYSGNLLASVGSNPDYTLTIWNWKEEQPILRTKAFSQEVFKVTFNPDKEEQLTTSGSGH 295
            F+    LL ++G +   TL +W       +  T+   + V  V FNP    +LT  G G 
Sbjct: 1214 FSPDDRLLVTLGDHDGRTLALWGTATYDLVSSTR-LPEPVHGVAFNPWDAGELTCVGQGT 1272

Query: 296  IKFWEMAFTFTGLKLQGSLGRFGKTITT-DIEGYMELPDGKVLSGSEWGNMLLWEGGLIK 354
            + FW +      + LQ       + +   ++          +  G+  G + +W+    +
Sbjct: 1273 VTFWLLQQRGADISLQVRREPVPEAVGAGELTSLCYGAPPLLYCGTSSGQVCVWDTRAGR 1332

Query: 355  VELCRGTSKSCHNGPINQIMLYEGEVITVGSDGYVRIWDFETIDTADVIDETGLLEIEPI 414
              L    S    +G I  ++     +++  S G +R+W    +        +G   +   
Sbjct: 1333 CFL----SWEADDGGIGLLLFSGSRLVSGSSTGRLRLWAVGAVSELRC-KGSGASSVFME 1387

Query: 415  NELQVDKNVNLFSMIKMNETGNNFWLAQDANGAIWKLDLSFSNITQDPECLFSFHSGAIE 474
            +EL +D  V   S     + G    +     G +W +  +    T+    L S H   + 
Sbjct: 1388 HELVLDGAVVSASFDDSVDMG----VVGTTAGTLWFVSWAEGTSTR----LISGHRSKVN 1439

Query: 475  AVAVSPLTYLMATTALDCSVRIYDFASKTPLAQMK-FKQGGTALVWVPRMVNFTGAQ-II 532
             V  SP     AT + D SVR++  AS   + Q +   Q    L W P        Q + 
Sbjct: 1440 EVVFSPGESHCATCSEDGSVRVWALASMELVIQFQVLNQSCLCLAWSPPCCGRPEQQRLA 1499

Query: 533  VGFEDGVVRILELYDPKGLTIFAGRKKILDADIQLKQVFKPHTACVTALAYERDGEILAT 592
             G+ DG +RI                 +    ++LK    PH   +T +A+  DG+ + +
Sbjct: 1500 AGYGDGSLRIFS---------------VSRTAMELKM--HPHPVALTTVAFSTDGQTVLS 1542

Query: 593  GSKDQTV 599
            G KD  V
Sbjct: 1543 GDKDGLV 1549


>gi|145580608 WD repeat domain 62 isoform 1 [Homo sapiens]
          Length = 1523

 Score = 57.0 bits (136), Expect = 8e-08
 Identities = 34/141 (24%), Positives = 67/141 (47%), Gaps = 3/141 (2%)

Query: 159 YIAGNQLIFLNLKTKEQIYLRSSSGEGIGVIGVHPHKTYFTVAEKGSFPDIIIYEYPSLR 218
           Y+AG  ++ L+ K  +Q ++ +++ + +  +   P   Y    E G  P + I++     
Sbjct: 87  YLAGCVVVILDPKENKQQHIFNTARKSLSALAFSPDGKYIVTGENGHRPAVRIWDVEEKN 146

Query: 219 PYRVLRDGTEKGYAYVDFNYSGNLLASVGSNPDYTLTIWNWKEEQPILRTKAFSQEVFKV 278
               +  G + G A V F+ +   + S+G   D  L +W+WK++  +   K  S  V  +
Sbjct: 147 QVAEML-GHKYGVACVAFSPNMKHIVSMGYQHDMVLNVWDWKKDIVVASNKV-SCRVIAL 204

Query: 279 TFNPDKEEQLTTSGSGHIKFW 299
           +F+ D      T G+ H++FW
Sbjct: 205 SFSED-SSYFVTVGNRHVRFW 224


>gi|145580610 WD repeat domain 62 isoform 2 [Homo sapiens]
          Length = 1518

 Score = 57.0 bits (136), Expect = 8e-08
 Identities = 34/141 (24%), Positives = 67/141 (47%), Gaps = 3/141 (2%)

Query: 159 YIAGNQLIFLNLKTKEQIYLRSSSGEGIGVIGVHPHKTYFTVAEKGSFPDIIIYEYPSLR 218
           Y+AG  ++ L+ K  +Q ++ +++ + +  +   P   Y    E G  P + I++     
Sbjct: 87  YLAGCVVVILDPKENKQQHIFNTARKSLSALAFSPDGKYIVTGENGHRPAVRIWDVEEKN 146

Query: 219 PYRVLRDGTEKGYAYVDFNYSGNLLASVGSNPDYTLTIWNWKEEQPILRTKAFSQEVFKV 278
               +  G + G A V F+ +   + S+G   D  L +W+WK++  +   K  S  V  +
Sbjct: 147 QVAEML-GHKYGVACVAFSPNMKHIVSMGYQHDMVLNVWDWKKDIVVASNKV-SCRVIAL 204

Query: 279 TFNPDKEEQLTTSGSGHIKFW 299
           +F+ D      T G+ H++FW
Sbjct: 205 SFSED-SSYFVTVGNRHVRFW 224


>gi|239745093 PREDICTED: hypothetical protein XP_002343359 [Homo
           sapiens]
          Length = 142

 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 27/53 (50%), Positives = 36/53 (67%), Gaps = 1/53 (1%)

Query: 690 EKRERQRELKEKIREERRNKLAAEMGEDGEKEFQEEEEEKEEEEEEEEPLPEI 742
           EKR  ++  +EK REE+R +      E+ EKE +EEEEE+EEEEEEEE   E+
Sbjct: 70  EKRREEKRREEKRREEKRREGKRREKEE-EKEEEEEEEEEEEEEEEEEEEEEV 121



 Score = 47.4 bits (111), Expect = 7e-05
 Identities = 23/47 (48%), Positives = 33/47 (70%)

Query: 691 KRERQRELKEKIREERRNKLAAEMGEDGEKEFQEEEEEKEEEEEEEE 737
           +R  ++  +EK REE+R +     G+  EKE ++EEEE+EEEEEEEE
Sbjct: 66  QRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEE 112



 Score = 35.4 bits (80), Expect = 0.26
 Identities = 21/57 (36%), Positives = 32/57 (56%), Gaps = 7/57 (12%)

Query: 688 EIEKRERQRELKEKIREERRNKLAAEMGEDGEKEFQEEEEE-------KEEEEEEEE 737
           E  + E++RE K + +EE + +   E  E+ E+E +EEEEE       +E E E EE
Sbjct: 80  EKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEE 136


>gi|17975763 myelin transcription factor 1 [Homo sapiens]
          Length = 1121

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 38/120 (31%), Positives = 56/120 (46%), Gaps = 23/120 (19%)

Query: 654 QEEDDHDVVSYEIK---DMCIKCFH--FSSVKSKILRLIEIEKRERQRELKEKIREERRN 708
           Q ED  +VV    +   D+C +      S   SK   ++  E+ + + E +E+  EE   
Sbjct: 217 QPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEE 276

Query: 709 KLAAEMGEDGEKEFQEEEEEKEEEEEEEEPL------------------PEIFIPSTPSP 750
           +   E  E+ E+E +EEEEE+EEEEEEEE                    PE+  P +PSP
Sbjct: 277 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSP 336


>gi|89886480 zinedin isoform 2 [Homo sapiens]
          Length = 760

 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 55/222 (24%), Positives = 93/222 (41%), Gaps = 22/222 (9%)

Query: 377 EGEVITVGSDGYVRIWDFETIDTADVIDETGLLEIEPINELQVDKNVNLFSMIKMNETGN 436
           +  ++T   DG +++W+ +   TA    +   L++EPI+  +  +   L   +  N   +
Sbjct: 457 QSALLTASEDGTLKLWNLQKAVTA---KKNAALDVEPIHAFRAHRGPVLAVAMGSN---S 510

Query: 437 NFWLAQDANGAI--WKL-DLSFSNIT-QDPECL---FSFHSGAIEAVAVSPLTYLMATTA 489
            +  +  A+  I  WK+ DLS       DP  L      H  A+  +A SP +  +A+ +
Sbjct: 511 EYCYSGGADACIHSWKIPDLSMDPYDGYDPSVLSHVLEGHGDAVWGLAFSPTSQRLASCS 570

Query: 490 LDCSVRIYDFASKTPLAQMKFKQGGTALVWVPRMVNFTG---AQIIVGFEDGVVRILELY 546
            D +VRI+D +S +P     F         VP  V FT    A I+  F  G      LY
Sbjct: 571 ADGTVRIWDPSSSSPACLCTFPTASEH--GVPTSVAFTSTEPAHIVASFRSGDT---VLY 625

Query: 547 DPK-GLTIFAGRKKILDADIQLKQVFKPHTACVTALAYERDG 587
           D + G  +     +      Q+ QV       +T  A++  G
Sbjct: 626 DMEVGSALLTLESRGSSGPTQINQVVSHPNQPLTITAHDDRG 667


>gi|89886477 zinedin isoform 1 [Homo sapiens]
          Length = 753

 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 55/222 (24%), Positives = 93/222 (41%), Gaps = 22/222 (9%)

Query: 377 EGEVITVGSDGYVRIWDFETIDTADVIDETGLLEIEPINELQVDKNVNLFSMIKMNETGN 436
           +  ++T   DG +++W+ +   TA    +   L++EPI+  +  +   L   +  N   +
Sbjct: 450 QSALLTASEDGTLKLWNLQKAVTA---KKNAALDVEPIHAFRAHRGPVLAVAMGSN---S 503

Query: 437 NFWLAQDANGAI--WKL-DLSFSNIT-QDPECL---FSFHSGAIEAVAVSPLTYLMATTA 489
            +  +  A+  I  WK+ DLS       DP  L      H  A+  +A SP +  +A+ +
Sbjct: 504 EYCYSGGADACIHSWKIPDLSMDPYDGYDPSVLSHVLEGHGDAVWGLAFSPTSQRLASCS 563

Query: 490 LDCSVRIYDFASKTPLAQMKFKQGGTALVWVPRMVNFTG---AQIIVGFEDGVVRILELY 546
            D +VRI+D +S +P     F         VP  V FT    A I+  F  G      LY
Sbjct: 564 ADGTVRIWDPSSSSPACLCTFPTASEH--GVPTSVAFTSTEPAHIVASFRSGDT---VLY 618

Query: 547 DPK-GLTIFAGRKKILDADIQLKQVFKPHTACVTALAYERDG 587
           D + G  +     +      Q+ QV       +T  A++  G
Sbjct: 619 DMEVGSALLTLESRGSSGPTQINQVVSHPNQPLTITAHDDRG 660


>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 123

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 28/57 (49%), Positives = 39/57 (68%), Gaps = 3/57 (5%)

Query: 680 KSKILRLIEIEKRERQRELKEKIREERRNKLAAEMGEDGEKEFQEEEEEKEEEEEEE 736
           K K  +  E EKR +++E +EK R+ +R K   E  E+ E+E +EEEEEKEEEE+EE
Sbjct: 40  KEKKKKTKETEKR-KEKEEEEKKRKRKRKKKKEE--EEREEEEEEEEEEKEEEEKEE 93



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 24/55 (43%), Positives = 35/55 (63%), Gaps = 1/55 (1%)

Query: 688 EIEKRERQREL-KEKIREERRNKLAAEMGEDGEKEFQEEEEEKEEEEEEEEPLPE 741
           E EK+++ +E  K K +EE   K   +  +  E+E +EEEEE+EEEE+EEE   E
Sbjct: 39  EKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEE 93



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 19/48 (39%), Positives = 34/48 (70%)

Query: 690 EKRERQRELKEKIREERRNKLAAEMGEDGEKEFQEEEEEKEEEEEEEE 737
           +++E++++ K K  E+R+ K   E     +++ ++EEEE+EEEEEEEE
Sbjct: 36  KRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEE 83



 Score = 39.3 bits (90), Expect = 0.018
 Identities = 23/58 (39%), Positives = 35/58 (60%), Gaps = 6/58 (10%)

Query: 690 EKRERQRELKEKIREERRNKLAAEMGEDGEK------EFQEEEEEKEEEEEEEEPLPE 741
           EKR+ +R+ KEK ++ +  +   E  E+ +K      + +EEEE +EEEEEEEE   E
Sbjct: 31  EKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEE 88



 Score = 38.1 bits (87), Expect = 0.041
 Identities = 22/58 (37%), Positives = 34/58 (58%), Gaps = 10/58 (17%)

Query: 690 EKRERQRELKEKIREERRNKLAAEMGEDGEKEFQEEEEE----------KEEEEEEEE 737
           E+ E++ + KEK +E+R+ K   +  ++ EK  ++EEEE          KEEEE EEE
Sbjct: 21  EEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEE 78



 Score = 35.0 bits (79), Expect = 0.35
 Identities = 21/61 (34%), Positives = 34/61 (55%), Gaps = 11/61 (18%)

Query: 688 EIEKRERQRELKEKIREERRNKLAAEMGEDGEKEFQEEEE-----------EKEEEEEEE 736
           E E+ E++R+ K K ++E   +   E  E+ EKE +E+EE            KEEEEE++
Sbjct: 54  EKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKK 113

Query: 737 E 737
           +
Sbjct: 114 K 114



 Score = 30.8 bits (68), Expect = 6.5
 Identities = 17/50 (34%), Positives = 31/50 (62%), Gaps = 4/50 (8%)

Query: 688 EIEKRERQRELKEKIREERRNKLAAEMGEDGEKEFQEEEEEKEEEEEEEE 737
           E E+ E + E + K +E+R+ K      E  +K+  +E E+++E+EEEE+
Sbjct: 15  ETEETEEEEEKEGKRKEKRKEKRK----EKEKKKKTKETEKRKEKEEEEK 60


>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
          Length = 843

 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 31/97 (31%), Positives = 49/97 (50%), Gaps = 8/97 (8%)

Query: 644 ILEAPLPTIKQEEDDHDVVSYEI---KDMCIKCFHFSSVKSKILRLIEIEKRERQRELKE 700
           I +  +  I+ EED  D++S EI   +D   K       K K  + IE E+RER+RE   
Sbjct: 259 ITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERE--- 315

Query: 701 KIREERRNKLAAEMGEDGEKEFQEEEEEKEEEEEEEE 737
             RE  R +   E   + E+E ++E+E + E E + +
Sbjct: 316 --RERERERREREREREREREREKEKERERERERDRD 350



 Score = 37.0 bits (84), Expect = 0.091
 Identities = 25/76 (32%), Positives = 37/76 (48%), Gaps = 22/76 (28%)

Query: 688 EIEKRERQRELKEKIREERRNKLAAEMGEDGEKEFQ----------------------EE 725
           E+E  ER R+ +++  EE R +L AE   D + E Q                      EE
Sbjct: 528 EMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEE 587

Query: 726 EEEKEEEEEEEEPLPE 741
           EE++E+EE+ EEP+ E
Sbjct: 588 EEKQEKEEKREEPMEE 603



 Score = 36.6 bits (83), Expect = 0.12
 Identities = 16/47 (34%), Positives = 29/47 (61%)

Query: 691 KRERQRELKEKIREERRNKLAAEMGEDGEKEFQEEEEEKEEEEEEEE 737
           +RER+RE + +   ER  +   E   + E+E + E+++K + EE+EE
Sbjct: 392 EREREREREREREREREREREREREREREREREREKDKKRDREEDEE 438



 Score = 34.3 bits (77), Expect = 0.59
 Identities = 19/58 (32%), Positives = 34/58 (58%), Gaps = 2/58 (3%)

Query: 696 RELKEKIREERRNKLAAEMGEDGEKEFQEEEEEKEEE--EEEEEPLPEIFIPSTPSPI 751
           + ++++    R+ ++  E   + E+E ++E+EEK EE  EEEEEP  +  +  T  PI
Sbjct: 563 QRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPCLKPTLRPI 620



 Score = 32.7 bits (73), Expect = 1.7
 Identities = 16/51 (31%), Positives = 29/51 (56%)

Query: 691 KRERQRELKEKIREERRNKLAAEMGEDGEKEFQEEEEEKEEEEEEEEPLPE 741
           +RER+RE + +   ER  +   E  +D +++ +E+EE+  E  + E  L E
Sbjct: 402 EREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLRE 452



 Score = 32.7 bits (73), Expect = 1.7
 Identities = 16/51 (31%), Positives = 31/51 (60%)

Query: 688 EIEKRERQRELKEKIREERRNKLAAEMGEDGEKEFQEEEEEKEEEEEEEEP 738
           E+++ E++ E + + + ++  +   E  E  EKE + EE  +EEEE E++P
Sbjct: 561 ELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKP 611


>gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo
           sapiens]
          Length = 631

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 22/39 (56%), Positives = 29/39 (74%)

Query: 699 KEKIREERRNKLAAEMGEDGEKEFQEEEEEKEEEEEEEE 737
           +E  REE   ++  E GE+ E+E +EEEEE+EEEEEEEE
Sbjct: 109 EETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEE 147



 Score = 38.5 bits (88), Expect = 0.031
 Identities = 24/56 (42%), Positives = 35/56 (62%), Gaps = 6/56 (10%)

Query: 686 LIEIEKRERQRELKEKIREERRNKLAAEMGEDGEKEFQEEEEEKEEEEEEEEPLPE 741
           L+  E+ ER+ E  E+I+EE       E  E+ E+E +EEEEE+EEEEE+    P+
Sbjct: 105 LVGEEETEREEE-DEEIQEE-----GGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQ 154



 Score = 33.1 bits (74), Expect = 1.3
 Identities = 17/51 (33%), Positives = 28/51 (54%), Gaps = 3/51 (5%)

Query: 234 VDFNYSGNLLASVGSNPDYTLTIWNWKEEQPILRTKA-FSQEVFKVTFNPD 283
           V FN  G  LAS G   D  + +W+W  ++P+L  ++  +  VF+  F P+
Sbjct: 234 VHFNQRGTRLASSGD--DLKVIVWDWVRQRPVLNFESGHTNNVFQAKFLPN 282



 Score = 31.2 bits (69), Expect = 5.0
 Identities = 24/77 (31%), Positives = 39/77 (50%), Gaps = 16/77 (20%)

Query: 655 EEDDHDVVSYEIKDMCIKCFHFSSVKSKILRLIEIEKRERQRELKEKIREERRNKLAAEM 714
           E+ +H ++S E        FH+  V  +     E E+ E   E++E+  EE       E 
Sbjct: 88  EDFEHFLMSGE------SLFHYPLVGEE-----ETEREEEDEEIQEEGGEEEE-----EE 131

Query: 715 GEDGEKEFQEEEEEKEE 731
            E+ E+E +EEEEE+E+
Sbjct: 132 EEEEEEEEEEEEEEEEQ 148


>gi|118600967 shroom family member 4 [Homo sapiens]
          Length = 1493

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 24/60 (40%), Positives = 37/60 (61%)

Query: 690  EKRERQRELKEKIREERRNKLAAEMGEDGEKEFQEEEEEKEEEEEEEEPLPEIFIPSTPS 749
            EK    R  +++ +++++ K   E  E+ E+E +EEEEE+EE EEEEE LP  +  S  S
Sbjct: 1110 EKYRLFRAAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEELPPQYFSSETS 1169



 Score = 32.3 bits (72), Expect = 2.2
 Identities = 15/46 (32%), Positives = 29/46 (63%)

Query: 685  RLIEIEKRERQRELKEKIREERRNKLAAEMGEDGEKEFQEEEEEKE 730
            RL    ++++Q++ ++K +EE   +   E  E+ E+E + EEEE+E
Sbjct: 1113 RLFRAAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEE 1158


>gi|28274705 family with sequence similarity 9, member A [Homo
           sapiens]
          Length = 332

 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 25/52 (48%), Positives = 32/52 (61%)

Query: 688 EIEKRERQRELKEKIREERRNKLAAEMGEDGEKEFQEEEEEKEEEEEEEEPL 739
           E E+ E + E +E+  EE   +   E G  GE E  EEEEE+EEEEEEEE +
Sbjct: 226 EKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQI 277



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 22/50 (44%), Positives = 30/50 (60%)

Query: 688 EIEKRERQRELKEKIREERRNKLAAEMGEDGEKEFQEEEEEKEEEEEEEE 737
           E E+ + + E KE+  EE   +   E GE+G    + EE E+EEEEEEEE
Sbjct: 222 EEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEE 271



 Score = 36.2 bits (82), Expect = 0.15
 Identities = 24/52 (46%), Positives = 28/52 (53%), Gaps = 2/52 (3%)

Query: 688 EIEKRERQRELKEKIREERRNKLAAEM--GEDGEKEFQEEEEEKEEEEEEEE 737
           E E+ E      E          AAE+   ED E+E +EEEEEKEEEEEE E
Sbjct: 190 EAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGE 241



 Score = 34.7 bits (78), Expect = 0.45
 Identities = 21/52 (40%), Positives = 30/52 (57%), Gaps = 1/52 (1%)

Query: 686 LIEIEKRERQRELKEKIREERRNKLAAEMGEDGEKEFQEEEEEKEEEEEEEE 737
           ++E E+ E + E +EK  EE   +     GE+GE+     E E+ EEEEEEE
Sbjct: 218 VVEDEEEEEKEEEEEKEEEEEEGEEEGG-GEEGEEGGGGGEGEETEEEEEEE 268



 Score = 32.0 bits (71), Expect = 2.9
 Identities = 15/27 (55%), Positives = 20/27 (74%)

Query: 710 LAAEMGEDGEKEFQEEEEEKEEEEEEE 736
           +  E  E+ EKE +EE+EE+EEE EEE
Sbjct: 217 IVVEDEEEEEKEEEEEKEEEEEEGEEE 243


>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
          Length = 709

 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 24/48 (50%), Positives = 31/48 (64%), Gaps = 6/48 (12%)

Query: 690 EKRERQRELKEKIREERRNKLAAEMGEDGEKEFQEEEEEKEEEEEEEE 737
           E  E   E++E   E+       E+ EDGE+E +EEEEE+EEEEEEEE
Sbjct: 207 EDVEEDEEVEEDAEEDE------EVDEDGEEEEEEEEEEEEEEEEEEE 248



 Score = 38.9 bits (89), Expect = 0.024
 Identities = 18/40 (45%), Positives = 29/40 (72%)

Query: 698 LKEKIREERRNKLAAEMGEDGEKEFQEEEEEKEEEEEEEE 737
           ++E + E+   +  AE  E+ +++ +EEEEE+EEEEEEEE
Sbjct: 205 VEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEE 244



 Score = 33.5 bits (75), Expect = 1.0
 Identities = 17/50 (34%), Positives = 30/50 (60%)

Query: 688 EIEKRERQRELKEKIREERRNKLAAEMGEDGEKEFQEEEEEKEEEEEEEE 737
           E E+ E   E  E++ E+   +   E  E+ E+E +EEE E++E +++EE
Sbjct: 211 EDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEE 260



 Score = 31.6 bits (70), Expect = 3.8
 Identities = 15/39 (38%), Positives = 23/39 (58%)

Query: 699 KEKIREERRNKLAAEMGEDGEKEFQEEEEEKEEEEEEEE 737
           +E + E+       E   + ++E  E+ EE+EEEEEEEE
Sbjct: 202 EEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEE 240



 Score = 30.8 bits (68), Expect = 6.5
 Identities = 16/50 (32%), Positives = 29/50 (58%)

Query: 688 EIEKRERQRELKEKIREERRNKLAAEMGEDGEKEFQEEEEEKEEEEEEEE 737
           ++E+ E   E  E+  E   +    E  E+ E+E +EEEEE+ E++E ++
Sbjct: 208 DVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQ 257


>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
          Length = 727

 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 24/48 (50%), Positives = 31/48 (64%), Gaps = 6/48 (12%)

Query: 690 EKRERQRELKEKIREERRNKLAAEMGEDGEKEFQEEEEEKEEEEEEEE 737
           E  E   E++E   E+       E+ EDGE+E +EEEEE+EEEEEEEE
Sbjct: 207 EDVEEDEEVEEDAEEDE------EVDEDGEEEEEEEEEEEEEEEEEEE 248



 Score = 38.9 bits (89), Expect = 0.024
 Identities = 18/40 (45%), Positives = 29/40 (72%)

Query: 698 LKEKIREERRNKLAAEMGEDGEKEFQEEEEEKEEEEEEEE 737
           ++E + E+   +  AE  E+ +++ +EEEEE+EEEEEEEE
Sbjct: 205 VEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEE 244



 Score = 33.5 bits (75), Expect = 1.0
 Identities = 17/50 (34%), Positives = 30/50 (60%)

Query: 688 EIEKRERQRELKEKIREERRNKLAAEMGEDGEKEFQEEEEEKEEEEEEEE 737
           E E+ E   E  E++ E+   +   E  E+ E+E +EEE E++E +++EE
Sbjct: 211 EDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEE 260



 Score = 31.6 bits (70), Expect = 3.8
 Identities = 15/39 (38%), Positives = 23/39 (58%)

Query: 699 KEKIREERRNKLAAEMGEDGEKEFQEEEEEKEEEEEEEE 737
           +E + E+       E   + ++E  E+ EE+EEEEEEEE
Sbjct: 202 EEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEE 240



 Score = 30.8 bits (68), Expect = 6.5
 Identities = 16/50 (32%), Positives = 29/50 (58%)

Query: 688 EIEKRERQRELKEKIREERRNKLAAEMGEDGEKEFQEEEEEKEEEEEEEE 737
           ++E+ E   E  E+  E   +    E  E+ E+E +EEEEE+ E++E ++
Sbjct: 208 DVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQ 257


>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
          Length = 1184

 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 26/47 (55%), Positives = 31/47 (65%), Gaps = 2/47 (4%)

Query: 690 EKRERQRELKEKIREERRNKLAAEMGEDGEKEFQEEEEEKEEEEEEE 736
           E  E  RE +E+I EE  +    E GED E E +EEEEE+EEEEEEE
Sbjct: 123 EDEEGDREEEEEIEEEDEDD--DEDGEDVEDEEEEEEEEEEEEEEEE 167



 Score = 31.6 bits (70), Expect = 3.8
 Identities = 18/64 (28%), Positives = 33/64 (51%), Gaps = 5/64 (7%)

Query: 678 SVKSKILRLIEIEKRERQRELKEKIREERRNKLAAEMGEDGEKEFQEEEEEKEEEEEEEE 737
           +VK+    + E +  +   ++ EK  +E       E  ED ++   E+EE++E + EEEE
Sbjct: 79  AVKADSSSVDECDDSDGTEDMDEKEEDE-----GEEYSEDNDEPGDEDEEDEEGDREEEE 133

Query: 738 PLPE 741
            + E
Sbjct: 134 EIEE 137


>gi|21071067 TBP-associated factor 5 [Homo sapiens]
          Length = 800

 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 50/204 (24%), Positives = 79/204 (38%), Gaps = 21/204 (10%)

Query: 216 SLRPYRVLRDGTEKGYAYVDFNYSGNLLASVGSNPDYTLTIWNWKEEQPILRTKAFSQEV 275
           SL+ +  L       Y   D  +S      V    D    +W     QP+        +V
Sbjct: 571 SLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADV 630

Query: 276 FKVTFNPDKEEQLTTSGSGHIKFWEMAFTFTGLKLQGSLGRFGKTITTDIEGYMELPDGK 335
               F+P+     T S    ++ W++        L G+  R        I      P+G+
Sbjct: 631 NCTRFHPNSNYVATGSADRTVRLWDV--------LNGNCVRIFTGHKGPIHSLTFSPNGR 682

Query: 336 VL-SGSEWGNMLLWE--GGLIKVELCRGTSKSCHNGPINQIMLYEGEVITVGS-DGYVRI 391
            L +G+  G +LLW+   GL+  EL   T   C     +     +GE++  GS D  VR+
Sbjct: 683 FLATGATDGRVLLWDIGHGLMVGELKGHTDTVC-----SLRFSRDGEILASGSMDNTVRL 737

Query: 392 WD----FETIDTADVIDETGLLEI 411
           WD    FE ++T D    TG + +
Sbjct: 738 WDAIKAFEDLETDDFTTATGHINL 761



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 41/166 (24%), Positives = 70/166 (42%), Gaps = 32/166 (19%)

Query: 462 PECLFSFHSGAIEAVAVSPLTYLMATTALDCSVRIYDFASKTPLAQMKFKQGGT-ALVWV 520
           P  +F+ H   +      P +  +AT + D +VR++D  +   +      +G   +L + 
Sbjct: 619 PLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFS 678

Query: 521 PRMVNFTGAQIIVGFEDGVVRILELYDPKGLTIFAGRKKILDADIQLKQVFKPHTACVTA 580
           P      G  +  G  DG V + ++    G  +  G               K HT  V +
Sbjct: 679 PN-----GRFLATGATDGRVLLWDI----GHGLMVGE-------------LKGHTDTVCS 716

Query: 581 LAYERDGEILATGSKDQTVFFFEVERDYKPI---------GYINTP 617
           L + RDGEILA+GS D TV  ++  + ++ +         G+IN P
Sbjct: 717 LRFSRDGEILASGSMDNTVRLWDAIKAFEDLETDDFTTATGHINLP 762



 Score = 40.0 bits (92), Expect = 0.011
 Identities = 40/159 (25%), Positives = 64/159 (40%), Gaps = 21/159 (13%)

Query: 469 HSGAIEAVAVSPLTYLMATTALDCSVRIYDFASKTPLAQMKFKQGGTALVWVPRMVNFTG 528
           HSG +   + SP    + +++ D +VR++   + T L   K   G    VW  +   + G
Sbjct: 542 HSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYK---GHNYPVWDTQFSPY-G 597

Query: 529 AQIIVGFEDGVVRILELYDPKGLTIFAGRKKILDADIQLKQVFKPHTACVTALAYERDGE 588
              + G  D V R+      + L IFAG                 H A V    +  +  
Sbjct: 598 YYFVSGGHDRVARLWATDHYQPLRIFAG-----------------HLADVNCTRFHPNSN 640

Query: 589 ILATGSKDQTVFFFEVERDYKPIGYINTPGPVCQLMWSP 627
            +ATGS D+TV  ++V        +    GP+  L +SP
Sbjct: 641 YVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSP 679


>gi|46276863 parathymosin [Homo sapiens]
          Length = 102

 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 21/53 (39%), Positives = 37/53 (69%), Gaps = 3/53 (5%)

Query: 688 EIEKRERQRELKEKIREERRN---KLAAEMGEDGEKEFQEEEEEKEEEEEEEE 737
           ++E++  ++E K+++ EE  N   +   E  EDGE+E + EEE++EEEEE++E
Sbjct: 23  KVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEEEEEDDE 75



 Score = 36.2 bits (82), Expect = 0.15
 Identities = 19/52 (36%), Positives = 32/52 (61%), Gaps = 6/52 (11%)

Query: 692 RERQRELKEKIREERRNKLAAEMGEDGEKEFQEE------EEEKEEEEEEEE 737
           +E++ +++EK   + R K   E  E+G +E +EE      EE++ EEE+EEE
Sbjct: 18  KEKKEKVEEKASRKERKKEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEE 69



 Score = 30.4 bits (67), Expect = 8.5
 Identities = 17/45 (37%), Positives = 23/45 (51%)

Query: 693 ERQRELKEKIREERRNKLAAEMGEDGEKEFQEEEEEKEEEEEEEE 737
           E   EL  K  +E++ K+  +      K+   EEEE   EEEEEE
Sbjct: 7   EAAAELSAKDLKEKKEKVEEKASRKERKKEVVEEEENGAEEEEEE 51


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.136    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,988,633
Number of Sequences: 37866
Number of extensions: 1964769
Number of successful extensions: 34478
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 494
Number of HSP's successfully gapped in prelim test: 342
Number of HSP's that attempted gapping in prelim test: 17627
Number of HSP's gapped (non-prelim): 10524
length of query: 982
length of database: 18,247,518
effective HSP length: 112
effective length of query: 870
effective length of database: 14,006,526
effective search space: 12185677620
effective search space used: 12185677620
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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