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Search of human proteins with 29029601
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|29029601 DEAH (Asp-Glu-Ala-His) box polypeptide 37 [Homo
sapiens]
(1157 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|29029601 DEAH (Asp-Glu-Ala-His) box polypeptide 37 [Homo sapi... 2306 0.0
gi|167830433 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 1... 235 2e-61
gi|39777586 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 [Homo ... 230 7e-60
gi|167830436 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 2... 228 3e-59
gi|4826690 DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Homo sapiens] 216 1e-55
gi|4503293 DEAH (Asp-Glu-Ala-His) box polypeptide 16 [Homo sapiens] 211 4e-54
gi|20544129 DEAH (Asp-Glu-Ala-His) box polypeptide 35 [Homo sapi... 207 4e-53
gi|20336302 DEAH (Asp-Glu-Ala-His) box polypeptide 33 [Homo sapi... 195 2e-49
gi|68509926 DEAH (Asp-Glu-Ala-His) box polypeptide 15 [Homo sapi... 192 2e-48
gi|17999539 DEAH (Asp-Glu-Ala-His) box polypeptide 38 [Homo sapi... 183 7e-46
gi|31542729 DEAH (Asp-Glu-Ala-His) box polypeptide 40 [Homo sapi... 171 4e-42
gi|169211440 PREDICTED: similar to DEAH (Asp-Glu-Ala-His) box po... 169 1e-41
gi|38158022 DEAH (Asp-Glu-Ala-His) box polypeptide 34 [Homo sapi... 157 7e-38
gi|67782362 DEAH (Asp-Glu-Ala-His) box polypeptide 29 [Homo sapi... 139 2e-32
gi|38505213 YTH domain containing 2 [Homo sapiens] 136 1e-31
gi|100913206 DEAH (Asp-Glu-Ala-His) box polypeptide 9 [Homo sapi... 133 9e-31
gi|20336290 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 2 ... 124 7e-28
gi|20336294 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 1 ... 124 7e-28
gi|166851804 tudor domain containing 9 [Homo sapiens] 123 9e-28
gi|20336300 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 32 [Hom... 108 2e-23
gi|163914394 DEAQ box polypeptide 1 (RNA-dependent ATPase) [Homo... 93 2e-18
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 58 5e-08
gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [H... 55 5e-07
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 53 1e-06
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 52 3e-06
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 51 7e-06
gi|110349719 titin isoform N2-A [Homo sapiens] 50 1e-05
gi|56549694 enabled homolog isoform a [Homo sapiens] 49 2e-05
gi|39930375 enabled homolog isoform b [Homo sapiens] 49 2e-05
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap... 49 4e-05
>gi|29029601 DEAH (Asp-Glu-Ala-His) box polypeptide 37 [Homo sapiens]
Length = 1157
Score = 2306 bits (5976), Expect = 0.0
Identities = 1157/1157 (100%), Positives = 1157/1157 (100%)
Query: 1 MGKLRRRYNIKGRQQAGPGPSKGPPEPPPVQLELEDKDTLKGVDASNALVLPGKKKKKTK 60
MGKLRRRYNIKGRQQAGPGPSKGPPEPPPVQLELEDKDTLKGVDASNALVLPGKKKKKTK
Sbjct: 1 MGKLRRRYNIKGRQQAGPGPSKGPPEPPPVQLELEDKDTLKGVDASNALVLPGKKKKKTK 60
Query: 61 APPLSKKEKKPLTKKEKKVLQKILEQKEKKSQRAEMLQKLSEVQASEAEMRLFYTTSKLG 120
APPLSKKEKKPLTKKEKKVLQKILEQKEKKSQRAEMLQKLSEVQASEAEMRLFYTTSKLG
Sbjct: 61 APPLSKKEKKPLTKKEKKVLQKILEQKEKKSQRAEMLQKLSEVQASEAEMRLFYTTSKLG 120
Query: 121 TGNRMYHTKEKADEVVAPGQEKISSLSGAHRKRRRWPSAEEEEEEEEESESELEEESELD 180
TGNRMYHTKEKADEVVAPGQEKISSLSGAHRKRRRWPSAEEEEEEEEESESELEEESELD
Sbjct: 121 TGNRMYHTKEKADEVVAPGQEKISSLSGAHRKRRRWPSAEEEEEEEEESESELEEESELD 180
Query: 181 EDPAAEPAEAGVGTTVAPLPPAPAPSSQPVPAGMTVPPPPAAAPPLPRALAKPAVFIPVN 240
EDPAAEPAEAGVGTTVAPLPPAPAPSSQPVPAGMTVPPPPAAAPPLPRALAKPAVFIPVN
Sbjct: 181 EDPAAEPAEAGVGTTVAPLPPAPAPSSQPVPAGMTVPPPPAAAPPLPRALAKPAVFIPVN 240
Query: 241 RSPEMQEERLKLPILSEEQVIMEAVAEHPIVIVCGETGSGKTTQVPQFLYEAGFSSEDSI 300
RSPEMQEERLKLPILSEEQVIMEAVAEHPIVIVCGETGSGKTTQVPQFLYEAGFSSEDSI
Sbjct: 241 RSPEMQEERLKLPILSEEQVIMEAVAEHPIVIVCGETGSGKTTQVPQFLYEAGFSSEDSI 300
Query: 301 IGVTEPRRVAAVAMSQRVAKEMNLSQRVVSYQIRYEGNVTEETRIKFMTDGVLLKEIQKD 360
IGVTEPRRVAAVAMSQRVAKEMNLSQRVVSYQIRYEGNVTEETRIKFMTDGVLLKEIQKD
Sbjct: 301 IGVTEPRRVAAVAMSQRVAKEMNLSQRVVSYQIRYEGNVTEETRIKFMTDGVLLKEIQKD 360
Query: 361 FLLLRYKVVIIDEAHERSVYTDILIGLLSRIVTLRAKRNLPLKLLIMSATLRVEDFTQNP 420
FLLLRYKVVIIDEAHERSVYTDILIGLLSRIVTLRAKRNLPLKLLIMSATLRVEDFTQNP
Sbjct: 361 FLLLRYKVVIIDEAHERSVYTDILIGLLSRIVTLRAKRNLPLKLLIMSATLRVEDFTQNP 420
Query: 421 RLFAKPPPVIKVESRQFPVTVHFNKRTPLEDYSGECFRKVCKIHRMLPAGGILVFLTGQA 480
RLFAKPPPVIKVESRQFPVTVHFNKRTPLEDYSGECFRKVCKIHRMLPAGGILVFLTGQA
Sbjct: 421 RLFAKPPPVIKVESRQFPVTVHFNKRTPLEDYSGECFRKVCKIHRMLPAGGILVFLTGQA 480
Query: 481 EVHALCRRLRKAFPPSRARPQEKDDDQKDSVEEMRKFKKSRARAKKARAEVLPQINLDHY 540
EVHALCRRLRKAFPPSRARPQEKDDDQKDSVEEMRKFKKSRARAKKARAEVLPQINLDHY
Sbjct: 481 EVHALCRRLRKAFPPSRARPQEKDDDQKDSVEEMRKFKKSRARAKKARAEVLPQINLDHY 540
Query: 541 SVLPAGEGDEDREAEVDEEEGALDSDLDLDLGDGGQDGGEQPDASLPLHVLPLYSLLAPE 600
SVLPAGEGDEDREAEVDEEEGALDSDLDLDLGDGGQDGGEQPDASLPLHVLPLYSLLAPE
Sbjct: 541 SVLPAGEGDEDREAEVDEEEGALDSDLDLDLGDGGQDGGEQPDASLPLHVLPLYSLLAPE 600
Query: 601 KQAQVFKPPPEGTRLCVVATNVAETSLTIPGIKYVVDCGKVKKRYYDRVTGVSSFRVTWV 660
KQAQVFKPPPEGTRLCVVATNVAETSLTIPGIKYVVDCGKVKKRYYDRVTGVSSFRVTWV
Sbjct: 601 KQAQVFKPPPEGTRLCVVATNVAETSLTIPGIKYVVDCGKVKKRYYDRVTGVSSFRVTWV 660
Query: 661 SQASADQRAGRAGRTEPGHCYRLYSSAVFGDFEQFPPPEITRRPVEDLILQMKALNVEKV 720
SQASADQRAGRAGRTEPGHCYRLYSSAVFGDFEQFPPPEITRRPVEDLILQMKALNVEKV
Sbjct: 661 SQASADQRAGRAGRTEPGHCYRLYSSAVFGDFEQFPPPEITRRPVEDLILQMKALNVEKV 720
Query: 721 INFPFPTPPSVEALLAAEELLIALGALQPPQKAERVKQLQENRLSCPITALGRTMATFPV 780
INFPFPTPPSVEALLAAEELLIALGALQPPQKAERVKQLQENRLSCPITALGRTMATFPV
Sbjct: 721 INFPFPTPPSVEALLAAEELLIALGALQPPQKAERVKQLQENRLSCPITALGRTMATFPV 780
Query: 781 APRYAKMLALSRQHGCLPYAITIVASMTVRELFEELDRPAASDEELTRLKSKRARVAQMK 840
APRYAKMLALSRQHGCLPYAITIVASMTVRELFEELDRPAASDEELTRLKSKRARVAQMK
Sbjct: 781 APRYAKMLALSRQHGCLPYAITIVASMTVRELFEELDRPAASDEELTRLKSKRARVAQMK 840
Query: 841 RTWAGQGASLKLGDLMVLLGAVGACEYASCTPQFCEANGLRYKAMMEIRRLRGQLTTAVN 900
RTWAGQGASLKLGDLMVLLGAVGACEYASCTPQFCEANGLRYKAMMEIRRLRGQLTTAVN
Sbjct: 841 RTWAGQGASLKLGDLMVLLGAVGACEYASCTPQFCEANGLRYKAMMEIRRLRGQLTTAVN 900
Query: 901 AVCPEAELFVDPKMQPPTESQVTYLRQIVTAGLGDHLARRVQSEEMLEDKWRNAYKTPLL 960
AVCPEAELFVDPKMQPPTESQVTYLRQIVTAGLGDHLARRVQSEEMLEDKWRNAYKTPLL
Sbjct: 901 AVCPEAELFVDPKMQPPTESQVTYLRQIVTAGLGDHLARRVQSEEMLEDKWRNAYKTPLL 960
Query: 961 DDPVFIHPSSVLFKELPEFVVYQEIVETTKMYMKGVSSVEVQWIPALLPSYCQFDKPLEE 1020
DDPVFIHPSSVLFKELPEFVVYQEIVETTKMYMKGVSSVEVQWIPALLPSYCQFDKPLEE
Sbjct: 961 DDPVFIHPSSVLFKELPEFVVYQEIVETTKMYMKGVSSVEVQWIPALLPSYCQFDKPLEE 1020
Query: 1021 PAPTYCPERGRVLCHRASVFYRVGWPLPAIEVDFPEGIDRYKHFARFLLEGQVFRKLASY 1080
PAPTYCPERGRVLCHRASVFYRVGWPLPAIEVDFPEGIDRYKHFARFLLEGQVFRKLASY
Sbjct: 1021 PAPTYCPERGRVLCHRASVFYRVGWPLPAIEVDFPEGIDRYKHFARFLLEGQVFRKLASY 1080
Query: 1081 RSCLLSSPGTMLKTWARLQPRTESLLRALVAEKADCHEALLAAWKKNPKYLLAEYCEWLP 1140
RSCLLSSPGTMLKTWARLQPRTESLLRALVAEKADCHEALLAAWKKNPKYLLAEYCEWLP
Sbjct: 1081 RSCLLSSPGTMLKTWARLQPRTESLLRALVAEKADCHEALLAAWKKNPKYLLAEYCEWLP 1140
Query: 1141 QAMHPDIEKAWPPTTVH 1157
QAMHPDIEKAWPPTTVH
Sbjct: 1141 QAMHPDIEKAWPPTTVH 1157
>gi|167830433 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 1
[Homo sapiens]
Length = 1008
Score = 235 bits (600), Expect = 2e-61
Identities = 180/591 (30%), Positives = 293/591 (49%), Gaps = 79/591 (13%)
Query: 244 EMQEERLKLPILSEEQVIMEAVAEHPIVIVCGETGSGKTTQVPQFLY----EAGFSSEDS 299
EMQ R KLP ++ ++ + H + ++ GETG GKTTQV QF+ E G S
Sbjct: 199 EMQHFREKLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQVTQFILDNYIERGKGSACR 258
Query: 300 IIGVTEPRRVAAVAMSQRVAKEMNLS---QRVVSYQIRYEGNVT-EETRIKFMTDGVLLK 355
I+ T+PRR++A+++++RVA E S YQIR + + ++ I + T G++L+
Sbjct: 259 IV-CTQPRRISAISVAERVAAERAESCGSGNSTGYQIRLQSRLPRKQGSILYCTTGIILQ 317
Query: 356 EIQKDFLLLRYKVVIIDEAHERSVYTDILIGLLSRIVTLRAKRNLPLKLLIMSATLRVED 415
+Q D L +++DE HER++ +D+L+ ++ ++ R+ LK+++MSATL E
Sbjct: 318 WLQSDPYLSSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSD----LKVILMSATLNAEK 373
Query: 416 FTQNPRLFAKPPPVIKVESRQFPVTVHFNKRTPLEDYSGECFRKVCKIHRMLPAGGILVF 475
F++ + P+I + FPV + LED V + R +P
Sbjct: 374 FSE----YFGNCPMIHIPGFTFPVVEYL-----LED--------VIEKIRYVPE------ 410
Query: 476 LTGQAEVHALCRRLRKAFPPSRARPQEKDDDQKDSVEEMRKF-KKSRARAKKARAEVLPQ 534
Q E + + ++ F QEK++ + E + ++ R R + +V+
Sbjct: 411 ---QKEHRS---QFKRGFMQGHVNRQEKEEKEAIYKERWPDYVRELRRRYSASTVDVIEM 464
Query: 535 INLDHY--SVLPAGEGDEDREAEVDEEEGALDSDLDLDLGDGGQDGGEQPDASLP----- 587
+ D +++ A R ++EE+GA+ L G + D +
Sbjct: 465 MEDDKVDLNLIVA----LIRYIVLEEEDGAI-----LVFLPGWDNISTLHDLLMSQVMFK 515
Query: 588 ---LHVLPLYSLLAPEKQAQVFKPPPEGTRLCVVATNVAETSLTIPGIKYVVDCGKVKKR 644
++PL+SL+ Q QVFK P G R V+ATN+AETS+TI + YV+D GK+K+
Sbjct: 516 SDKFLIIPLHSLMPTVNQTQVFKRTPPGVRKIVIATNIAETSITIDDVVYVIDGGKIKET 575
Query: 645 YYDRVTGVSSFRVTWVSQASADQRAGRAGRTEPGHCYRLYSSAVFGDFEQFPPPEITRRP 704
++D +S+ WVS+A+A QR GRAGR +PGHCY LY+ + + PEI R P
Sbjct: 576 HFDTQNNISTMSAEWVSKANAKQRKGRAGRVQPGHCYHLYNGLRASLLDDYQLPEILRTP 635
Query: 705 VEDLILQMKALNVEKVINF--PFPTPPSVEALLAAEELLIALGALQPPQKAERVKQLQEN 762
+E+L LQ+K L + + F PPS EA+L + L+ L AL ++
Sbjct: 636 LEELCLQIKILRLGGIAYFLSRLMDPPSNEAVLLSIRHLMELNALDKQEE---------- 685
Query: 763 RLSCPITALGRTMATFPVAPRYAKMLALSRQHGCLPYAITIVASMTVRELF 813
+T LG +A PV P KM+ CL +TI AS++ ++ F
Sbjct: 686 -----LTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLTIAASLSFKDPF 731
>gi|39777586 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 [Homo
sapiens]
Length = 1386
Score = 230 bits (586), Expect = 7e-60
Identities = 196/688 (28%), Positives = 318/688 (46%), Gaps = 85/688 (12%)
Query: 247 EERLKLPILSEEQVIMEAVAEHPIVIVCGETGSGKTTQVPQFLYEAGFSSEDSIIG---V 303
+ER LP E + I+ + +H +V++ G TG GKTTQ+PQF+ + + +
Sbjct: 539 QERQSLPAWEERETILNLLRKHQVVVISGMTGCGKTTQIPQFILDDSLNGPPEKVANIIC 598
Query: 304 TEPRRVAAVAMSQRVAKEMNLSQRV---VSYQIRYEGNVTEETRIKFMTDGVLLKEIQKD 360
T+PRR++A+++++RVAKE ++RV V YQIR E + TR+ + T GVLL+ ++ D
Sbjct: 599 TQPRRISAISVAERVAKER--AERVGLTVGYQIRLESVKSSATRLLYCTTGVLLRRLEGD 656
Query: 361 FLLLRYKVVIIDEAHERSVYTDILIGLLSRIVTLRAKRNLPLKLLIMSATLRVEDFTQNP 420
L +I+DE HER+ +D L+ +L IV+ R L++++MSATL E F+
Sbjct: 657 TALQGVSHIIVDEVHERTEESDFLLLVLKDIVSQRPG----LQVILMSATLNAELFSD-- 710
Query: 421 RLFAKPPPVIKVESRQFPVTVHFNKRTPLEDYSGECFRKVCKIHRMLPAGGILVFLTGQA 480
+ PVI + R FPV F LED + +L G + Q
Sbjct: 711 --YFNSCPVITIPGRTFPVDQFF-----LED-------AIAVTRYVLQDGSPYMRSMKQI 756
Query: 481 EVHAL-CRRLRKAFPPSRARPQ-----EKDDDQKDSVEEMR-KFKKSRARAKKARAEVLP 533
L RR R AF + + D KD+V + + FK+ AR K V+
Sbjct: 757 SKEKLKARRNRTAFEEVEEDLRLSLHLQDQDSVKDAVPDQQLDFKQLLARYKGVSKSVIK 816
Query: 534 QINLDHYSVLPAGEGDEDREAEVDEEE------------GALDSDLDLDLGDGGQDGGEQ 581
+++ + + + E VD + G + + + +
Sbjct: 817 TMSIMDFEKVNLELIEALLEWIVDGKHSYPPGAILVFLPGLAEIKMLYEQLQSNSLFNNR 876
Query: 582 PDASLPLHVLPLYSLLAPEKQAQVFKPPPEGTRLCVVATNVAETSLTIPGIKYVVDCGKV 641
+H PL+S L+ E+Q VF PP G +++TN+AETS+TI + YV+D GK+
Sbjct: 877 RSNRCVIH--PLHSSLSSEEQQAVFVKPPAGVTKIIISTNIAETSITIDDVVYVIDSGKM 934
Query: 642 KKRYYDRVTGVSSFRVTWVSQASADQRAGRAGRTEPGHCYRLYSSAVFG-DFEQFPPPEI 700
K++ YD G+ S T+VSQA+A QR GRAGR G C+ L++S + + PEI
Sbjct: 935 KEKRYDASKGMESLEDTFVSQANALQRKGRAGRVASGVCFHLFTSHHYNHQLLKQQLPEI 994
Query: 701 TRRPVEDLILQMKALNVEKVINFP-----FPTPPSVEALLAAEELLIALGALQPPQKAER 755
R P+E L L++K L + N PP ++L A++ L LGAL P ++
Sbjct: 995 QRVPLEQLCLRIKILEMFSAHNLQSVFSRLIEPPHTDSLRASKIRLRDLGALTPDER--- 1051
Query: 756 VKQLQENRLSCPITALGRTMATFPVAPRYAKMLALSRQHGCLPYAITIVASMTVRELF-E 814
+T LG +A+ PV R K++ CL A+TI AS+ + F
Sbjct: 1052 ------------LTPLGYHLASLPVDVRIGKLMLFGSIFRCLDPALTIAASLAFKSPFVS 1099
Query: 815 ELDRPAASDEELTRLKSKRARVAQMKRTWAGQGASLKLGDLMVLLGAVGACEYASCTPQF 874
D+ ++++ + + + + G S K G + +
Sbjct: 1100 PWDKKEEANQKKLEFAFANSDYLALLQAYKGWQLSTKEG--------------VRASYNY 1145
Query: 875 CEANGLRYKAMMEIRRLRGQLTTAVNAV 902
C N L + + E+ L+ Q T ++ +
Sbjct: 1146 CRQNFLSGRVLQEMASLKRQFTELLSDI 1173
>gi|167830436 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 2
[Homo sapiens]
Length = 994
Score = 228 bits (581), Expect = 3e-59
Identities = 179/584 (30%), Positives = 289/584 (49%), Gaps = 79/584 (13%)
Query: 244 EMQEERLKLPILSEEQVIMEAVAEHPIVIVCGETGSGKTTQVPQFLY----EAGFSSEDS 299
EMQ R KLP ++ ++ + H + ++ GETG GKTTQV QF+ E G S
Sbjct: 199 EMQHFREKLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQVTQFILDNYIERGKGSACR 258
Query: 300 IIGVTEPRRVAAVAMSQRVAKEMNLS---QRVVSYQIRYEGNVT-EETRIKFMTDGVLLK 355
I+ T+PRR++A+++++RVA E S YQIR + + ++ I + T G++L+
Sbjct: 259 IV-CTQPRRISAISVAERVAAERAESCGSGNSTGYQIRLQSRLPRKQGSILYCTTGIILQ 317
Query: 356 EIQKDFLLLRYKVVIIDEAHERSVYTDILIGLLSRIVTLRAKRNLPLKLLIMSATLRVED 415
+Q D L +++DE HER++ +D+L+ ++ ++ R+ LK+++MSATL E
Sbjct: 318 WLQSDPYLSSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSD----LKVILMSATLNAEK 373
Query: 416 FTQNPRLFAKPPPVIKVESRQFPVTVHFNKRTPLEDYSGECFRKVCKIHRMLPAGGILVF 475
F++ + P+I + FPV + LED V + R +P
Sbjct: 374 FSE----YFGNCPMIHIPGFTFPVVEYL-----LED--------VIEKIRYVPE------ 410
Query: 476 LTGQAEVHALCRRLRKAFPPSRARPQEKDDDQKDSVEEMRKF-KKSRARAKKARAEVLPQ 534
Q E + + ++ F QEK++ + E + ++ R R + +V+
Sbjct: 411 ---QKEHRS---QFKRGFMQGHVNRQEKEEKEAIYKERWPDYVRELRRRYSASTVDVIEM 464
Query: 535 INLDHY--SVLPAGEGDEDREAEVDEEEGALDSDLDLDLGDGGQDGGEQPDASLPLHVLP 592
+ D +++ A R ++EE+GA+ L G D LH L
Sbjct: 465 MEDDKVDLNLIVA----LIRYIVLEEEDGAILVFLP------GWDNIST------LHDLL 508
Query: 593 LYSLLAPE-KQAQVFKPPPEGTRLCVVATNVAETSLTIPGIKYVVDCGKVKKRYYDRVTG 651
+ ++ Q QVFK P G R V+ATN+AETS+TI + YV+D GK+K+ ++D
Sbjct: 509 MSQVMFKSVNQTQVFKRTPPGVRKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNN 568
Query: 652 VSSFRVTWVSQASADQRAGRAGRTEPGHCYRLYSSAVFGDFEQFPPPEITRRPVEDLILQ 711
+S+ WVS+A+A QR GRAGR +PGHCY LY+ + + PEI R P+E+L LQ
Sbjct: 569 ISTMSAEWVSKANAKQRKGRAGRVQPGHCYHLYNGLRASLLDDYQLPEILRTPLEELCLQ 628
Query: 712 MKALNVEKVINF--PFPTPPSVEALLAAEELLIALGALQPPQKAERVKQLQENRLSCPIT 769
+K L + + F PPS EA+L + L+ L AL ++ +T
Sbjct: 629 IKILRLGGIAYFLSRLMDPPSNEAVLLSIRHLMELNALDKQEE---------------LT 673
Query: 770 ALGRTMATFPVAPRYAKMLALSRQHGCLPYAITIVASMTVRELF 813
LG +A PV P KM+ CL +TI AS++ ++ F
Sbjct: 674 PLGVHLARLPVEPHIGKMILFGALFCCLDPVLTIAASLSFKDPF 717
>gi|4826690 DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Homo sapiens]
Length = 1220
Score = 216 bits (550), Expect = 1e-55
Identities = 143/432 (33%), Positives = 220/432 (50%), Gaps = 54/432 (12%)
Query: 588 LHVLPLYSLLAPEKQAQVFKPPPEGTRLCVVATNVAETSLTIPGIKYVVDCGKVKKRYYD 647
L +LP+YS L E Q ++F P P G+R V+ATN+AETSLTI GI YVVD G VK++ Y+
Sbjct: 807 LIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYN 866
Query: 648 RVTGVSSFRVTWVSQASADQRAGRAGRTEPGHCYRLYSSAVFGD-FEQFPPPEITRRPVE 706
TG+ VT +SQA A QRAGRAGRT PG CYRLY+ + D PEI R +
Sbjct: 867 SKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLA 926
Query: 707 DLILQMKALNVEKVINFPFPTPPSVEALLAAEELLIALGALQPPQKAERVKQLQENRLSC 766
+L +KA+ + +++F F P +E L+ A E L LGAL
Sbjct: 927 STVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLGALDDEGL-------------- 972
Query: 767 PITALGRTMATFPVAPRYAKMLALSRQHGCLPYAITIVASMTVRELF-EELDRPAASDEE 825
+T LGR MA FP+ P KML +S GC +TIV+ ++V+ +F D+ A +D+
Sbjct: 973 -LTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDKQALADQ- 1030
Query: 826 LTRLKSKRARVAQMKRTWAGQGASLKLGDLMVLLGAVGACEYASCTPQFCEANGLRYKAM 885
K+A+ Q + GD + LL + + + +C N ++ +++
Sbjct: 1031 ------KKAKFHQTE------------GDHLTLLAVYNSWKNNKFSNPWCYENFIQARSL 1072
Query: 886 MEIRRLRGQLTTAVNAVCPEAELFVDPKMQPPTESQVTYLRQIVTAGLGDHLARRVQSEE 945
+ +R Q+ + +L V +++ + +G + A++ E
Sbjct: 1073 RRAQDIRKQML----GIMDRHKLDV-----VSCGKSTVRVQKAICSGFFRNAAKKDPQE- 1122
Query: 946 MLEDKWRNAYKTPLLDDPVFIHPSSVLFKELPEFVVYQEIVETTKMYMKGVSSVEVQWIP 1005
Y+T + V+IHPSS LF PE+VVY E+V TTK YM+ V++++ +W+
Sbjct: 1123 --------GYRTLIDQQVVYIHPSSALFNRQPEWVVYHELVLTTKEYMREVTTIDPRWLV 1174
Query: 1006 ALLPSYCQFDKP 1017
P++ + P
Sbjct: 1175 EFAPAFFKVSDP 1186
Score = 177 bits (448), Expect = 7e-44
Identities = 104/245 (42%), Positives = 154/245 (62%), Gaps = 13/245 (5%)
Query: 247 EERLKLPILSEEQVIMEAVAEHPIVIVCGETGSGKTTQVPQFLYEAGFSSEDSIIGVTEP 306
E+R LPI ++ +++AV ++ I+IV GETGSGKTTQ+ Q+L EAG++S I G T+P
Sbjct: 560 EQRESLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTSRGKI-GCTQP 618
Query: 307 RRVAAVAMSQRVAKEMN--LSQRVVSYQIRYEGNVTEETRIKFMTDGVLLKEIQKDFLLL 364
RRVAA+++++RV++E L Q V Y IR+E + ET IK+MTDG+LL+E D L
Sbjct: 619 RRVAAMSVAKRVSEEFGCCLGQEV-GYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLT 677
Query: 365 RYKVVIIDEAHERSVYTDILIGLLSRIVTLRAKRNLPLKLLIMSATLRVEDFTQNPRLFA 424
+Y ++++DEAHER+++TD+L GLL + V ++ +KL++ SATL F+Q +
Sbjct: 678 QYAIIMLDEAHERTIHTDVLFGLLKKTV----QKRQDMKLIVTSATLDAVKFSQ----YF 729
Query: 425 KPPPVIKVESRQFPVTVHFNKRTPLEDYSGECFRKVCKIHRMLPAGGILVFLTGQAEVHA 484
P+ + R +PV + + K P DY V +IH P G ILVFLTGQ E+
Sbjct: 730 YEAPIFTIPGRTYPVEILYTKE-PETDYLDASLITVMQIHLTEPPGDILVFLTGQEEIDT 788
Query: 485 LCRRL 489
C L
Sbjct: 789 ACEIL 793
>gi|4503293 DEAH (Asp-Glu-Ala-His) box polypeptide 16 [Homo sapiens]
Length = 1041
Score = 211 bits (536), Expect = 4e-54
Identities = 152/445 (34%), Positives = 226/445 (50%), Gaps = 57/445 (12%)
Query: 588 LHVLPLYSLLAPEKQAQVFKPPPEGTRLCVVATNVAETSLTIPGIKYVVDCGKVKKRYYD 647
L VLP+Y+ L + QA++F+P P G R VVATN+AETS TI GI YV+D G K++ Y+
Sbjct: 642 LLVLPIYANLPSDMQARIFQPTPPGARKVVVATNIAETSPTIEGIIYVLDPGFCKQKSYN 701
Query: 648 RVTGVSSFRVTWVSQASADQRAGRAGRTEPGHCYRLYSS-AVFGDFEQFPPPEITRRPVE 706
TG+ S VT S+ASA+QRAGRAGR G C+RLY++ A + E+ PEI R +
Sbjct: 702 PRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFRLYTAWAYQHELEETTVPEIQRTSLG 761
Query: 707 DLILQMKALNVEKVINFPFPTPPSVEALLAAEELLIALGALQPPQKAERVKQLQENRLSC 766
+++L +K+L + +++F F PP E LL E L ALGAL N L
Sbjct: 762 NVVLLLKSLGIHDLMHFDFLDPPPYETLLLTLEQLYALGAL--------------NHLG- 806
Query: 767 PITALGRTMATFPVAPRYAKMLALSRQHGCLPYAITIVASMTVRE--LFEELDRPAASDE 824
+T GR MA PV P +KM+ S ++ C +T+ A ++V + D+ +D
Sbjct: 807 ELTTSGRKMAELPVDPMLSKMILASEKYSCSEEILTVAAMLSVNNSIFYRPKDKVVHAD- 865
Query: 825 ELTRLKSKRARVAQMKRTWAGQGASLKLGDLMVLLGAVGACEYASCTPQFCEANGLRYKA 884
ARV L GD +VLL + + Q+C N +++++
Sbjct: 866 --------NARV----------NFFLPGGDHLVLLNVYTQWAESGYSSQWCCENFVQFRS 907
Query: 885 MMEIRRLRGQLTTAVNAVCPEAELFVDPKMQPPTESQVTYLRQIVTAGLGDHLARRVQSE 944
M R +R QL + V E L + +R+ +TAG H AR
Sbjct: 908 MRRARDVREQLEGLLERV--EVGL-------SSCQGDYIRVRKAITAGYFYHTARLT--- 955
Query: 945 EMLEDKWRNAYKTPLLDDPVFIHPSSVLFKELPEFVVYQEIVETTKMYMKGVSSVEVQWI 1004
R+ Y+T VFIHP+S LF++ P +++Y E+V TTK +M+ V +E W+
Sbjct: 956 -------RSGYRTVKQQQTVFIHPNSSLFEQQPRWLLYHELVLTTKEFMRQVLEIESSWL 1008
Query: 1005 PALLPSYCQFDKPLEEPAPTYCPER 1029
+ P Y + K LE+P P++
Sbjct: 1009 LEVAPHYYK-AKELEDPHAKKMPKK 1032
Score = 207 bits (526), Expect = 6e-53
Identities = 155/506 (30%), Positives = 253/506 (50%), Gaps = 45/506 (8%)
Query: 11 KGRQQAGPGPSKGPPEPPPVQLELE--DKDTLKGVDASNALVLPGKKKKKTKAPPLSKKE 68
KG+++ G SK E P + E E +++ L+ ++ +A +++ K + + ++
Sbjct: 143 KGKKKTGG--SKQQTEKPESEDEWERTERERLQDLEERDAFAERVRQRDKDRTRNVLERS 200
Query: 69 KKPLTKKEKKVLQKILEQKE------KKSQRAEML-----QKLSEVQASEAEMRLFYTTS 117
K ++ +K L+ E ++ +K R E L +KL +++A A+ +
Sbjct: 201 DKKAYEEAQKRLKMAEEDRKAMIPELRKKSRREYLAKREREKLEDLEAELADEEFLFGDV 260
Query: 118 KLGTGNRMY-----HTKEKADEVVAPG-QEKISSLSGAHR-KRRRWPSAEEEEEEEEESE 170
+L R ++ A E A G QEK+ + + H K R A + EEES
Sbjct: 261 ELSRHERQELKYKRRVRDLAREYRAAGEQEKLEATNRYHMPKETRGQPARAVDLVEEESG 320
Query: 171 SELEEESELDEDPAAEPAEAGVGTTVAPLPPAPAPSSQP-----VPAGMTVPPPPAAAPP 225
+ EE+ +E A +G A S +P + T+ A
Sbjct: 321 APGEEQRRWEE--------ARLGAASLKFGARDAASQEPKYQLVLEEEETIEFVRATQLQ 372
Query: 226 LPRALAKPAVFIPVNRSPEMQEERLKLPILSEEQVIMEAVAEHPIVIVCGETGSGKTTQV 285
+ P + +Q R LP+ + ++ A+A H ++I+ GETGSGKTTQ+
Sbjct: 373 GDEEPSAPPTSTQAQQKESIQAVRRSLPVFPFREELLAAIANHQVLIIEGETGSGKTTQI 432
Query: 286 PQFLYEAGFSSEDSIIGVTEPRRVAAVAMSQRVAKEMNLS-QRVVSYQIRYEGNVTEETR 344
PQ+L+E G++++ I T+PRRVAA++++ RVA+EM + V Y IR+E +E T
Sbjct: 433 PQYLFEEGYTNKGMKIACTQPRRVAAMSVAARVAREMGVKLGNEVGYSIRFEDCTSERTV 492
Query: 345 IKFMTDGVLLKEIQKDFLLLRYKVVIIDEAHERSVYTDILIGLLSRIVTLRAKRNLPLKL 404
+++MTDG+LL+E + L Y VV++DEAHER+++TDIL GL+ + R + LK+
Sbjct: 493 LRYMTDGMLLREFLSEPDLASYSVVMVDEAHERTLHTDILFGLIKDVARFRPE----LKV 548
Query: 405 LIMSATLRVEDFTQNPRLFAKPPPVIKVESRQFPVTVHFNKRTPLEDYSGECFRKVCKIH 464
L+ SAT+ F+ F PV ++ R+FPV + + K P DY C V +IH
Sbjct: 549 LVASATMDTARFS----TFFDDAPVFRIPGRRFPVDIFYTK-APEADYLEACVVSVLQIH 603
Query: 465 RMLPAGGILVFLTGQAEVHALCRRLR 490
P G ILVFLTGQ E+ A C L+
Sbjct: 604 VTQPPGDILVFLTGQEEIEAACEMLQ 629
>gi|20544129 DEAH (Asp-Glu-Ala-His) box polypeptide 35 [Homo sapiens]
Length = 703
Score = 207 bits (528), Expect = 4e-53
Identities = 148/428 (34%), Positives = 216/428 (50%), Gaps = 53/428 (12%)
Query: 588 LHVLPLYSLLAPEKQAQVFKPPPEGTRLCVVATNVAETSLTIPGIKYVVDCGKVKKRYYD 647
L VLP+Y+ L +Q +VF+ R +VATNVAETS+TI GI YV+DCG VK R Y+
Sbjct: 310 LRVLPMYAGLPSFEQMKVFERVSRSVRKVIVATNVAETSITISGIVYVIDCGFVKLRAYN 369
Query: 648 RVTGVSSFRVTWVSQASADQRAGRAGRTEPGHCYRLYSSAVFGDFEQFPPPEITRRPVED 707
T + V VSQASA+QRAGR GR+ G CYRLY+ F Q PE+ R +
Sbjct: 370 PRTAIECLVVVPVSQASANQRAGRGGRSRSGKCYRLYTEEAFDKLPQSTVPEMQRSNLAP 429
Query: 708 LILQMKALNVEKVINFPFPTPPSVEALLAAEELLIALGALQPPQKAERVKQLQENRLSCP 767
+ILQ+KAL ++ V+ F F +PP ++++ A ELL ALG L ++ RL+ P
Sbjct: 430 VILQLKALGIDNVLRFHFMSPPPAQSMVQALELLYALGGLD-----------KDCRLTEP 478
Query: 768 ITALGRTMATFPVAPRYAKMLALSRQHGCLPYAITIVASMTVRELFEELDRPAASDEELT 827
LG +A FP+ P +AKML S GC ++I A M ++ +F P
Sbjct: 479 ---LGMRIAEFPLNPMFAKMLLESGNFGCSQEILSIAAMMQIQNIFVV---PPNQKSHAI 532
Query: 828 RLKSKRARVAQMKRTWAGQGASLKLGDLMVLLGAVGACEYASCTPQFCEANGLRYKAMME 887
R+ K A ++ GD + +L A + ++C+ + L YK ++
Sbjct: 533 RVHRKFA---------------VEEGDHLTMLNIYEAFIKHNKDSKWCQEHFLNYKGLVR 577
Query: 888 IRRLRGQL-TTAVNAVCPEAELFVDPKMQPPTESQVTYLRQIVTAGLGDHLARRVQSEEM 946
+R QL V P DP + LR IV+ + A R S
Sbjct: 578 AATVREQLKKLLVKFQVPRKSSEGDPDL---------VLRCIVSGFFAN--AARFHS--- 623
Query: 947 LEDKWRNAYKTPLLDDPVFIHPSSVLFKEL-PEFVVYQEIVETTKMYMKGVSSVEVQWIP 1005
AY+T D + IHP+SVL+ E P +V+Y E+++T+K YM+ V+++E W+
Sbjct: 624 -----TGAYRTIRDDHELHIHPASVLYAEKPPRWVIYNEVIQTSKYYMRDVTAIESAWLL 678
Query: 1006 ALLPSYCQ 1013
L P + Q
Sbjct: 679 ELAPHFYQ 686
Score = 176 bits (447), Expect = 9e-44
Identities = 103/253 (40%), Positives = 156/253 (61%), Gaps = 13/253 (5%)
Query: 245 MQEERLKLPILSEEQVIMEAVAEHPIVIVCGETGSGKTTQVPQFLYEAGFSSEDSIIGVT 304
++++R KLP+ I+ + + V++ GETG GK+TQ+PQ+L EAG+++E ++GVT
Sbjct: 47 IEQQRQKLPVFKLRNHILYLIENYQTVVIVGETGCGKSTQIPQYLAEAGWTAEGRVVGVT 106
Query: 305 EPRRVAAVAMSQRVAKEMN-LSQRVVSYQIRYEGNVTE-ETRIKFMTDGVLLKEIQKDFL 362
+PRRVAAV ++ RVA+E + V Y IR++ + TRIKF+TDG+L++E+ D L
Sbjct: 107 QPRRVAAVTVAGRVAEERGAVLGHEVGYCIRFDDCTDQLATRIKFLTDGMLVREMMVDPL 166
Query: 363 LLRYKVVIIDEAHERSVYTDILIGLLSRIVTLRAKRNLPLKLLIMSATLRVEDFTQ--NP 420
L +Y V+++DEAHER++YTDI IGLL +I K+ L+L++ SATL + F N
Sbjct: 167 LTKYSVIMLDEAHERTLYTDIAIGLLKKI----QKKRGDLRLIVASATLDADKFRDFFNQ 222
Query: 421 RLFAKPP----PVIKVESRQFPVTVHFNKRTPLEDYSGECFRKVCKIHRMLPAGGILVFL 476
+ P ++ VE R FPV + F ++P+ DY V KIH+ G +L FL
Sbjct: 223 NETSDPARDTCVILTVEGRTFPVDI-FYLQSPVPDYIKSTVETVVKIHQTEGDGDVLAFL 281
Query: 477 TGQAEVHALCRRL 489
TGQ EV + L
Sbjct: 282 TGQEEVETVVSML 294
>gi|20336302 DEAH (Asp-Glu-Ala-His) box polypeptide 33 [Homo sapiens]
Length = 707
Score = 195 bits (496), Expect = 2e-49
Identities = 138/430 (32%), Positives = 214/430 (49%), Gaps = 48/430 (11%)
Query: 582 PDASLPLHVLPLYSLLAPEKQAQVFKPPPEGTRLCVVATNVAETSLTIPGIKYVVDCGKV 641
PD + VLPLY+ L +Q +VF+ P+G R +++TN+AETS+TI GIKYVVD G V
Sbjct: 316 PDGCPAMLVLPLYASLPYAQQLRVFQGAPKGYRKVIISTNIAETSITITGIKYVVDTGMV 375
Query: 642 KKRYYDRVTGVSSFRVTWVSQASADQRAGRAGRTEPGHCYRLYSSAVFGDFEQFPPPEIT 701
K + Y+ +G+ V VS+ A QR GRAGR + G CYRLY+ F F++ PEI
Sbjct: 376 KAKKYNPDSGLEVLAVQRVSKTQAWQRTGRAGREDSGICYRLYTEDEFEKFDKMTVPEIQ 435
Query: 702 RRPVEDLILQMKALNVEKVINFPFPTPPSVEALLAAEELLIALGALQPPQKAERVKQLQE 761
R + ++LQ+ A+ V V+ F F + PS + + AA L LGAL+ ++
Sbjct: 436 RCNLASVMLQLLAMKVPNVLTFDFMSKPSPDHIQAAIAQLDLLGALEH----------KD 485
Query: 762 NRLSCPITALGRTMATFPVAPRYAKMLALSRQHGCLPYAITIVASMTVRELFEELDRPAA 821
++L+ +T +GR MA FP+ P++AK + +S + C +TIV+ ++V
Sbjct: 486 DQLT--LTPMGRKMAAFPLEPKFAKTILMSPKFHCTEEILTIVSLLSV------------ 531
Query: 822 SDEELTRLKSKRARVAQMKRTWAGQGASLKLGDLMVLLGAVGACEYASCTPQFCEANGLR 881
D L S+R V +++ + GD M LL + +C+ N +
Sbjct: 532 -DSVLHNPPSRREEVQGVRKKFISSE-----GDHMTLLNIYRTFKNLGGNKDWCKENFVN 585
Query: 882 YKAMMEIRRLRGQLTTAVNAVCPEAELFVDPKMQPPTESQVTYLRQIVTAGLGDHLARRV 941
K M + +R QL +C + + + + V +R+ + L +
Sbjct: 586 SKNMTLVAEVRAQL----RDICLKMSMPI-----ASSRGDVESVRRCLAHSL------FM 630
Query: 942 QSEEMLEDKWRNAYKTPLLDDPVFIHPSSVLFKELPEFVVYQEIVETTKMYMKGVSSVEV 1001
+ E+ D Y T PV IHPSSVLF P VVY E++ T K YM+ + ++
Sbjct: 631 STAELQPD---GTYATTDTHQPVAIHPSSVLFHCKPACVVYTELLYTNKCYMRDLCVIDA 687
Query: 1002 QWIPALLPSY 1011
QW+ P Y
Sbjct: 688 QWLYEAAPEY 697
Score = 187 bits (474), Expect = 7e-47
Identities = 114/278 (41%), Positives = 167/278 (60%), Gaps = 21/278 (7%)
Query: 224 PPLPRALAKPAVFIPVNRSPEMQE-ERLKLPILSEEQVIMEAVAEHPIVIVCGETGSGKT 282
PPL + A P PE E +R LPI ++ + ++ GETGSGKT
Sbjct: 53 PPLAQPSASPY--------PEAVELQRRSLPIFQARGQLLAQLRNLDNAVLIGETGSGKT 104
Query: 283 TQVPQFLYEAGFSSEDSIIGVTEPRRVAAVAMSQRVAKEMNLSQ-RVVSYQIRYEGNVTE 341
TQ+PQ+LYE G S + II VT+PRRVAA++++ RV+ E ++V Y +R++ +E
Sbjct: 105 TQIPQYLYEGGISRQ-GIIAVTQPRRVAAISLATRVSDEKRTELGKLVGYTVRFDDVTSE 163
Query: 342 ETRIKFMTDGVLLKEIQKDFLLLRYKVVIIDEAHERSVYTDILIGLLSRIVTLRAK-RNL 400
+TRIKF+TDG+LL+E D LL +Y VI+DEAHER+++TD+L G++ R + L
Sbjct: 164 DTRIKFLTDGMLLREAISDSLLRKYSCVILDEAHERTIHTDVLFGVVKAAQKRRKELGKL 223
Query: 401 PLKLLIMSATLRVEDFTQNPRLFAKPPPVIKVESRQFPVTVHFNKRTPLEDYSGECFRKV 460
PLK+++MSAT+ V+ F+Q + PV+ +E RQ P+ V + K+ P DY V
Sbjct: 224 PLKVIVMSATMDVDLFSQ----YFNGAPVLYLEGRQHPIQVFYTKQ-PQNDYLHAALVSV 278
Query: 461 CKIHRMLPAG-GILVFLTGQAEVHAL---CRRLRKAFP 494
+IH+ P+ ILVFLTGQ E+ A+ CR + K P
Sbjct: 279 FQIHQEAPSSQDILVFLTGQEEIEAMSKTCRDIAKHLP 316
>gi|68509926 DEAH (Asp-Glu-Ala-His) box polypeptide 15 [Homo sapiens]
Length = 795
Score = 192 bits (487), Expect = 2e-48
Identities = 142/468 (30%), Positives = 230/468 (49%), Gaps = 70/468 (14%)
Query: 553 EAEVDEEEGALDSDLDLDLGDGGQDGGEQPDASLPLHVLPLYSLLAPEKQAQVFKPPPEG 612
+ E+DE + ++D D G + G+ + ++PLYS L P++Q ++F+PPP
Sbjct: 359 QEEIDEACKRIKREVD----DLGPEVGD-------IKIIPLYSTLPPQQQQRIFEPPPPK 407
Query: 613 T------RLCVVATNVAETSLTIPGIKYVVDCGKVKKRYYDRVTGVSSFRVTWVSQASAD 666
R VV+TN+AETSLTI G+ +V+D G K++ Y+ V S VT +S+ASA
Sbjct: 408 KQNGAIGRKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQ 467
Query: 667 QRAGRAGRTEPGHCYRLYSSAVF-GDFEQFPPPEITRRPVEDLILQMKALNVEKVINFPF 725
QRAGRAGRT PG C+RLY+ + + + PEI R + ++LQ+K L ++ +++F F
Sbjct: 468 QRAGRAGRTRPGKCFRLYTEKAYKTEMQDNTYPEILRSNLGSVVLQLKKLGIDDLVHFDF 527
Query: 726 PTPPSVEALLAAEELLIALGALQPPQKAERVKQLQENRLSCPITALGRTMATFPVAPRYA 785
PP+ E L+ A ELL L AL +T LG MA FP+ P+ A
Sbjct: 528 MDPPAPETLMRALELLNYLAALND---------------DGDLTELGSMMAEFPLDPQLA 572
Query: 786 KMLALSRQHGCLPYAITIVASMTVRELFEELDRPAASDEELTRLKSKRARVAQMKRTWAG 845
KM+ S + C ++I A ++V + F RP + + K + A +
Sbjct: 573 KMVIASCDYNCSNEVLSITAMLSVPQCFV---RPTEAKKAADEAKMRFAHID-------- 621
Query: 846 QGASLKLGDLMVLLGAVGACEYASCTPQFCEANGLRYKAMMEIRRLRGQLTTAVNAVCPE 905
GD + LL A + + Q+C N + Y+++M +R QL+ +
Sbjct: 622 -------GDHLTLLNVYHAFKQNHESVQWCYDNFINYRSLMSADNVRQQLSRIM------ 668
Query: 906 AELFVDPKMQPPTESQVTY--LRQIVTAGLGDHLARRVQSEEMLEDKWRNAYKTPLLDDP 963
+ F P+ S+ Y +R+ + G +A ++ Y T +
Sbjct: 669 -DRFNLPRRSTDFTSRDYYINIRKALVTGYFMQVAHLERT---------GHYLTVKDNQV 718
Query: 964 VFIHPSSVLFKELPEFVVYQEIVETTKMYMKGVSSVEVQWIPALLPSY 1011
V +HPS+VL PE+V+Y E V TTK Y++ + ++ +W+ + P Y
Sbjct: 719 VQLHPSTVL-DHKPEWVLYNEFVLTTKNYIRTCTDIKPEWLVKIAPQY 765
Score = 170 bits (430), Expect = 8e-42
Identities = 117/353 (33%), Positives = 190/353 (53%), Gaps = 22/353 (6%)
Query: 151 RKRRRWPSAEEEEEEEEESESELEEESELDEDPAAEPAEAGVGTTVAPLPPA-------P 203
R R R +++ + E + + E E E E +++ A + + PL +
Sbjct: 29 RDRDREDRSKDRDRERDRGDREREREKEKEKELRASTNAMLISAGLPPLKASHSAHSTHS 88
Query: 204 APSSQPVPAGMTVPPPPAAAPPLPRALAKPAVFIP-VNRSPEMQEERLKLPILSEEQVIM 262
A S+ + + A LP+ + P +P R ++ ++RL+LP+ +
Sbjct: 89 AHSTHSTHSAHSTHAGHAGHTSLPQCI-NPFTNLPHTPRYYDILKKRLQLPVWEYKDRFT 147
Query: 263 EAVAEHPIVIVCGETGSGKTTQVPQFLYEAGFSSEDSIIGV--TEPRRVAAVAMSQRVAK 320
+ + H ++ GETGSGKTTQ+PQ+ E S GV T+PRRVAA++++QRVA
Sbjct: 148 DILVRHQSFVLVGETGSGKTTQIPQWCVEYMRSLPGPKRGVACTQPRRVAAMSVAQRVAD 207
Query: 321 EMNLSQ-RVVSYQIRYEGNVTEETRIKFMTDGVLLKEIQKDFLLLRYKVVIIDEAHERSV 379
EM++ + V Y IR+E + +T +K+MTDG+LL+E D LL RY V+I+DEAHER++
Sbjct: 208 EMDVMLGQEVGYSIRFEDCSSAKTILKYMTDGMLLREAMNDPLLERYGVIILDEAHERTL 267
Query: 380 YTDILIGLLSRIVTLRAKRNLPLKLLIMSATLRVEDFTQNPRLFAKPPPVIKVESRQFPV 439
TDIL+G+L +V R+ LK+++MSATL F +++ P++ + R PV
Sbjct: 268 ATDILMGVLKEVVRQRS----DLKVIVMSATLDAGKF----QIYFDNCPLLTIPGRTHPV 319
Query: 440 TVHFNKRTPLEDYSGECFRKVCKIHRM-LPAGGILVFLTGQAEVHALCRRLRK 491
+ + P DY R V +IH G +L+FLTGQ E+ C+R+++
Sbjct: 320 EIFYTPE-PERDYLEAAIRTVIQIHMCEEEEGDLLLFLTGQEEIDEACKRIKR 371
>gi|17999539 DEAH (Asp-Glu-Ala-His) box polypeptide 38 [Homo sapiens]
Length = 1227
Score = 183 bits (465), Expect = 7e-46
Identities = 131/436 (30%), Positives = 218/436 (50%), Gaps = 56/436 (12%)
Query: 580 EQPDASLPLHVLPLYSLLAPEKQAQVFKPPPEGTRLCVVATNVAETSLTIPGIKYVVDCG 639
E+ + + L VLP+YS L + QA++F+ P+G R C+VATN+AETSLT+ GI +V+D G
Sbjct: 765 EELENAPALAVLPIYSQLPSDLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSG 824
Query: 640 KVKKRYYDRVTGVSSFRVTWVSQASADQRAGRAGRTEPGHCYRLYS-SAVFGDFEQFPPP 698
K + ++ G+ + ++ +SQA+A+QR+GRAGRT PG C+RLY+ SA + P
Sbjct: 825 YCKLKVFNPRIGMDALQIYPISQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVP 884
Query: 699 EITRRPVEDLILQMKALNVEKVINFPFPTPPSVEALLAAEELLIALGALQPPQKAERVKQ 758
EI R + +++L +K+L V+ ++ F F PP + +L + L LGAL
Sbjct: 885 EIQRTNLANVVLLLKSLGVQDLLQFHFMDPPPEDNMLNSMYQLWILGALDN--------- 935
Query: 759 LQENRLSCPITALGRTMATFPVAPRYAKMLALSRQHGCLPYAITIVASMTVRELFEELDR 818
+ +T+ GR M FP+ P +KML +S GC + IV+ ++V +F R
Sbjct: 936 ------TGGLTSTGRLMVEFPLDPALSKMLIVSCDMGCSSEILLIVSMLSVPAIFY---R 986
Query: 819 PAASDEELTRLKSKRARVAQMKRTWAGQGASLKLGDLMVLLGAVGACEYASCTPQFCEAN 878
P +EE +++ K A + D + L + + + +C +
Sbjct: 987 PKGREEESDQIREKFA---------------VPESDHLTYLNVYLQWKNNNYSTIWCNDH 1031
Query: 879 GLRYKAMMEIRRLRGQLTTAVNAVCPEAELFVDPKMQ-PPTESQVTYLRQIVTAGLGDHL 937
+ KAM ++R +R QL ++ V +M + +R+ + A
Sbjct: 1032 FIHAKAMRKVREVRAQL----------KDIMVQQRMSLASCGTDWDIVRKCICAAYFHQA 1081
Query: 938 ARRVQSEEMLEDKWRNAYKTPLLDDPVFIHPSSVLF--KELPEFVVYQEIVETTKMYMKG 995
A+ K Y P +HP+S LF P+++VY E+V TTK YM+
Sbjct: 1082 AKL---------KGIGEYVNIRTGMPCHLHPTSSLFGMGYTPDYIVYHELVMTTKEYMQC 1132
Query: 996 VSSVEVQWIPALLPSY 1011
V++V+ +W+ L P +
Sbjct: 1133 VTAVDGEWLAELGPMF 1148
Score = 175 bits (444), Expect = 2e-43
Identities = 101/238 (42%), Positives = 153/238 (64%), Gaps = 13/238 (5%)
Query: 247 EERLKLPILSEEQVIMEAVAEHPIVIVCGETGSGKTTQVPQFLYEAGFSSEDSIIGVTEP 306
E+R LPI + +Q ++ + ++ IVIV GETGSGKTTQ+ Q+L+E G++ + +IG T+P
Sbjct: 527 EQRQYLPIFAVQQELLTIIRDNSIVIVVGETGSGKTTQLTQYLHEDGYT-DYGMIGCTQP 585
Query: 307 RRVAAVAMSQRVAKEM--NLSQRVVSYQIRYEGNVTEETRIKFMTDGVLLKEIQKDFLLL 364
RRVAA+++++RV++EM NL + V Y IR+E +E T IK+MTDG+LL+E ++ L
Sbjct: 586 RRVAAMSVAKRVSEEMGGNLGEEV-GYAIRFEDCTSENTLIKYMTDGILLRESLREADLD 644
Query: 365 RYKVVIIDEAHERSVYTDILIGLLSRIVTLRAKRNLPLKLLIMSATLRVEDFTQNPRLFA 424
Y +I+DEAHERS+ TD+L GLL +V R+ LKL++ SAT+ E F F
Sbjct: 645 HYSAIIMDEAHERSLNTDVLFGLLREVVARRS----DLKLIVTSATMDAEKFA----AFF 696
Query: 425 KPPPVIKVESRQFPVTVHFNKRTPLEDYSGECFRKVCKIHRMLPAGGILVFLTGQAEV 482
P+ + R FPV + F+K TP EDY ++ ++H G IL+F+ GQ ++
Sbjct: 697 GNVPIFHIPGRTFPVDILFSK-TPQEDYVEAAVKQSLQVHLSGAPGDILIFMPGQEDI 753
>gi|31542729 DEAH (Asp-Glu-Ala-His) box polypeptide 40 [Homo sapiens]
Length = 779
Score = 171 bits (433), Expect = 4e-42
Identities = 130/457 (28%), Positives = 209/457 (45%), Gaps = 60/457 (13%)
Query: 566 DLDLDLGDGGQDGGEQPDASLPLHVLPLYSLLAPEKQAQVFKPPPEGTRLCVVATNVAET 625
D D D+ D DG L +LP Y + ++Q ++F PPP G R CV++TN++ T
Sbjct: 300 DYDYDVQDTTLDG---------LLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISAT 350
Query: 626 SLTIPGIKYVVDCGKVKKRYYDRVTGVSSFRVTWVSQASADQRAGRAGRTEPGHCYRLYS 685
SLTI GI+YVVD G VK+ ++ G+ V +S++ A QR+GRAGRT G C+R+YS
Sbjct: 351 SLTIDGIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYS 410
Query: 686 SAVFGD-FEQFPPPEITRRPVEDLILQMKALNVEKVINFPFPTPPSVEALLAAEELLIAL 744
+ PEI R + ++L +K L + VI FP+ PP+ +L A + L
Sbjct: 411 KDFWNQCMPDHVIPEIKRTSLTSVVLTLKCLAIHDVIRFPYLDPPNERLILEALKQLYQC 470
Query: 745 GALQPPQKAERVKQLQENRLSCPITALGRTMATFPVAPRYAKMLALSRQHGCLPYAITIV 804
A+ S +T LG +M FP+ P + + C + I
Sbjct: 471 DAID---------------RSGHVTRLGLSMVEFPLPPHLTCAVIKAASLDCEDLLLPIA 515
Query: 805 ASMTVRELFEELDRPAASDEELTRLKSKRARVAQMKRTWAGQGASLKLGDLMVLLGAVGA 864
A ++V +F RP D E + +R R K AG D L
Sbjct: 516 AMLSVENVF---IRPV--DPEYQKEAEQRHRELAAK---AG-----GFNDFATLAVIFEQ 562
Query: 865 CEYASCTPQFCEANGLRYKAMMEIRRLRGQLTTAVNAVCPEA----ELFVDPKMQPPTES 920
C+ + +C+ + + ++ + R+ QL + + ++ E F PK +
Sbjct: 563 CKSSGAPASWCQKHWIHWRCLFSAFRVEAQLRELIRKLKQQSDFPKETFEGPKHE----- 617
Query: 921 QVTYLRQIVTAGLGDHLARRVQSEEMLEDKWRNAYKTPLLDDPVFIHPSSVLFKELP--E 978
LR+ + AG ++ARR R + PV IHPSS L ++ E
Sbjct: 618 ---VLRRCLCAGYFKNVARRSVGRTFCTVDGRGS--------PVHIHPSSALHEQETKLE 666
Query: 979 FVVYQEIVETTKMYMKGVSSVEVQWIPALLPSYCQFD 1015
++++ E++ TTK+Y + V + +W+ LLP +F+
Sbjct: 667 WIIFHEVLVTTKVYARIVCPIRYEWVRDLLPKLHEFN 703
Score = 168 bits (426), Expect = 2e-41
Identities = 109/278 (39%), Positives = 157/278 (56%), Gaps = 34/278 (12%)
Query: 241 RSPEMQEERLK----------------------LPILSEEQVIMEAVAEHPIVIVCGETG 278
RS ++QEERL PI + + I++AV ++ +IV G TG
Sbjct: 20 RSRDLQEERLSAVCIADREEKGCTSQEGGTTPTFPIQKQRKKIIQAVRDNSFLIVTGNTG 79
Query: 279 SGKTTQVPQFLYEAGFSSEDSIIGVTEPRRVAAVAMSQRVAKEMNLSQ-RVVSYQIRYEG 337
SGKTTQ+P++LYEAGFS + +IGVT+PR+VAA++++QRVA+EM + V YQ+R++
Sbjct: 80 SGKTTQLPKYLYEAGFS-QHGMIGVTQPRKVAAISVAQRVAEEMKCTLGSKVGYQVRFDD 138
Query: 338 NVTEETRIKFMTDGVLLKEIQKDFLLLRYKVVIIDEAHERSVYTDILIGLLSRIVTLRA- 396
++ET IK+MTDG LLK I D L ++ V+I+DEAHER++ TDIL GLL ++ ++
Sbjct: 139 CSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTLTTDILFGLLKKLFQEKSP 198
Query: 397 KRNLPLKLLIMSATLRVEDFTQNPRLFAKPPPVIKVESRQFPVTVHFNKRTPLED----- 451
R LK+++MSAT+ + + F P+ + R +PV F D
Sbjct: 199 NRKEHLKVVVMSATMELAKLS----AFFGNCPIFDIPGRLYPVREKFCNLIGPRDRENTA 254
Query: 452 YSGECFRKVCKIHRMLPAGGILVFLTGQAEVHALCRRL 489
Y IH AG ILVFLTGQ E+ C L
Sbjct: 255 YIQAIVEVTMDIHLNEMAGDILVFLTGQFEIEKSCELL 292
>gi|169211440 PREDICTED: similar to DEAH (Asp-Glu-Ala-His) box
polypeptide 40 [Homo sapiens]
Length = 452
Score = 169 bits (429), Expect = 1e-41
Identities = 110/278 (39%), Positives = 162/278 (58%), Gaps = 34/278 (12%)
Query: 241 RSPEMQEERLK----------------------LPILSEEQVIMEAVAEHPIVIVCGETG 278
RS ++QEERL PI + + I++AV ++ +IV G TG
Sbjct: 20 RSRDLQEERLSAVCIADREEKGCTSQEGGTTPTFPIQKQRKKIIQAVRDNSFLIVTGNTG 79
Query: 279 SGKTTQVPQFLYEAGFSSEDSIIGVTEPRRVAAVAMSQRVAKEMNLSQ-RVVSYQIRYEG 337
SGKTTQ+P++LYEAGFS + +IGVT+PR+VAA++++QRVA+EM + V YQ+R++
Sbjct: 80 SGKTTQLPKYLYEAGFS-QHGMIGVTQPRKVAAISVAQRVAEEMKCTLGSKVGYQVRFDD 138
Query: 338 NVTEETRIKFMTDGVLLKEIQKDFLLLRYKVVIIDEAHERSVYTDILIGLLSRIVTLRA- 396
++ET IK+MTDG LLK I D L ++ V+I+DEAHER++ TDIL GLL ++ ++
Sbjct: 139 CSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTLTTDILFGLLKKLFQEKSP 198
Query: 397 KRNLPLKLLIMSATLRVEDFTQNPRLFAKPPPVIKVESRQFPVTVHF-NKRTPLEDYSGE 455
R LK+++MSAT+ + + F P+ + R +PV F N P + +
Sbjct: 199 NRKEHLKVVVMSATMELAKLS----AFFGNCPIFDIPGRLYPVREKFCNLIGPRDRENTA 254
Query: 456 CFRKVCK----IHRMLPAGGILVFLTGQAEVHALCRRL 489
+ + K IH AG ILVFLTGQ E+ C L
Sbjct: 255 YIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCELL 292
Score = 109 bits (272), Expect = 2e-23
Identities = 61/159 (38%), Positives = 90/159 (56%), Gaps = 10/159 (6%)
Query: 566 DLDLDLGDGGQDGGEQPDASLPLHVLPLYSLLAPEKQAQVFKPPPEGTRLCVVATNVAET 625
D D D+ D DG L +LP Y + ++Q ++F PPP G R CV++TN++ T
Sbjct: 300 DYDYDVQDTILDG---------LLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISAT 350
Query: 626 SLTIPGIKYVVDCGKVKKRYYDRVTGVSSFRVTWVSQASADQRAGRAGRTEPGHCYRLYS 685
SLTI GI+YVVD G VK+ ++ G+ V +S++ A QR+GRAGRT G C+R+YS
Sbjct: 351 SLTIDGIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYS 410
Query: 686 SAVFGD-FEQFPPPEITRRPVEDLILQMKALNVEKVINF 723
+ PEI R + ++L +K L + VI +
Sbjct: 411 KDFWNQCMPDHVIPEIKRTSLTSVVLTLKCLAIHDVIRY 449
>gi|38158022 DEAH (Asp-Glu-Ala-His) box polypeptide 34 [Homo
sapiens]
Length = 1143
Score = 157 bits (396), Expect = 7e-38
Identities = 97/257 (37%), Positives = 155/257 (60%), Gaps = 25/257 (9%)
Query: 241 RSPEMQEERLKLPILSEEQVIMEAVAEHPIVIVCGETGSGKTTQVPQFLYEAGFSSEDSI 300
R ++Q ER LPI I++ + EH +V+V G+TG GK+TQVPQ+L AGFS
Sbjct: 151 RLAKLQRERAALPIAQYGNRILQTLKEHQVVVVAGDTGCGKSTQVPQYLLAAGFSH---- 206
Query: 301 IGVTEPRRVAAVAMSQRVAKEMNLSQ--RVVSYQIRYEGNVTEETRIKFMTDGVLLKEIQ 358
+ T+PRR+A +++++RV E +LSQ V YQIR+E + T+I F+T G+LL++IQ
Sbjct: 207 VACTQPRRIACISLAKRVGFE-SLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQ 265
Query: 359 KDFLLLRYKVVIIDEAHERSVYTDILIGLLSRIVTLRAKRNLPLKLLIMSATLRVEDFTQ 418
++ L +Y+V+I+DE HER ++ D L+G+L R++ R LK+++MSAT+ + F+
Sbjct: 266 REPSLPQYEVLIVDEVHERHLHNDFLLGVLQRLLPTRP----DLKVILMSATINISLFSS 321
Query: 419 NPRLFAKPPPVIKVESRQFPVTVHFNKR------TPLEDYSGECFRKVCKI--HRMLP-- 468
+ PV++V R FP+TV + + + E F +V + H+ P
Sbjct: 322 ----YFSNAPVVQVPGRLFPITVVYQPQEAEPTTSKSEKLDPRPFLRVLESIDHKYPPEE 377
Query: 469 AGGILVFLTGQAEVHAL 485
G +LVFL+G AE+ A+
Sbjct: 378 RGDLLVFLSGMAEISAV 394
Score = 154 bits (390), Expect = 4e-37
Identities = 89/224 (39%), Positives = 126/224 (56%), Gaps = 15/224 (6%)
Query: 590 VLPLYSLLAPEKQAQVFKPPPEGTRLCVVATNVAETSLTIPGIKYVVDCGKVKKRYYDRV 649
VLPL+S L+ Q +VF P G R C+++TN+AETS+TI GI++VVD GKVK+ YD
Sbjct: 410 VLPLHSALSVADQDKVFDVAPPGVRKCILSTNIAETSVTIDGIRFVVDSGKVKEMSYDPQ 469
Query: 650 TGVSSFRVTWVSQASADQRAGRAGRTEPGHCYRLYSSAVFGDFEQFPPPEITRRPVEDLI 709
+ + W+SQASA+QR GRAGRT PG C+RLY+ + + F +P PEI R ++ L+
Sbjct: 470 AKLQRLQEFWISQASAEQRKGRAGRTGPGVCFRLYAESDYDAFAPYPVPEIRRVALDSLV 529
Query: 710 LQMKALNVEKVINFPFPTPPSVEALLAAEELLIALGALQPPQKAERVKQLQENRLSCPIT 769
LQMK+++V FPF PP +L A L GAL + +T
Sbjct: 530 LQMKSMSVGDPRTFPFIEPPPPASLETAILYLRDQGALDSSE---------------ALT 574
Query: 770 ALGRTMATFPVAPRYAKMLALSRQHGCLPYAITIVASMTVRELF 813
+G +A PV KML L + +TI A+++V+ F
Sbjct: 575 PIGSLLAQLPVDVVIGKMLILGSMFSLVEPVLTIAAALSVQSPF 618
>gi|67782362 DEAH (Asp-Glu-Ala-His) box polypeptide 29 [Homo sapiens]
Length = 1369
Score = 139 bits (350), Expect = 2e-32
Identities = 117/416 (28%), Positives = 192/416 (46%), Gaps = 41/416 (9%)
Query: 590 VLPLYSLLAPEKQAQVFKPPPEGTRLCVVATNVAETSLTIPGIKYVVDCGKVKKRYYDRV 649
V+ L+S+L+ + QA F PP G R V+ATN+AET +TIP + +V+D G+ K+ Y
Sbjct: 900 VIALHSILSTQDQAAAFTLPPPGVRKIVLATNIAETGITIPDVVFVIDTGRTKENKYHES 959
Query: 650 TGVSSFRVTWVSQASADQRAGRAGRTEPGHCYRLYSSAVFGDFEQFPPPEITRRPVEDLI 709
+ +SS T+VS+ASA QR GRAGR G C+R+Y+ F F + PEI R P+E+L
Sbjct: 960 SQMSSLVETFVSKASALQRQGRAGRVRDGFCFRMYTRERFEGFMDYSVPEILRVPLEELC 1019
Query: 710 LQMKALNVEKVINFPFPT--PPSVEALLAAEELLIALGALQPPQKAERVKQLQENRLSCP 767
L + N+ +F PP ++ + A LL +GA +L E +L
Sbjct: 1020 LHIMKCNLGSPEDFLSKALDPPQLQVISNAMNLLRKIGAC----------ELNEPKL--- 1066
Query: 768 ITALGRTMATFPVAPRYAKMLALSRQHGCLPYAITIVASMTVRELFEELDRPAASDEELT 827
T LG+ +A PV + KML GCL T+ A MT + F P +E
Sbjct: 1067 -TPLGQHLAALPVNVKIGKMLIFGAIFGCLDPVATLAAVMTEKSPF---TTPIGRKDEAD 1122
Query: 828 RLKSKRARVAQMKRTWAGQGASLKLGDLMVLLGAVGACEYASCTPQ--FCEANGLRYKAM 885
KS A S L LG A + + +C N L ++
Sbjct: 1123 LAKSALA-----------MADSDHLTIYNAYLGWKKARQEGGYRSEITYCRRNFLNRTSL 1171
Query: 886 MEIRRLRGQLTTAVNAV-----CPEAELFVDPKMQPPTESQVTYLRQIVTAGLGDHLARR 940
+ + ++ +L V A + Q + ++ L+ ++ AGL D++ +
Sbjct: 1172 LTLEDVKQELIKLVKAAGFSSSTTSTSWEGNRASQTLSFQEIALLKAVLVAGLYDNVGKI 1231
Query: 941 VQSEEM-LEDKWRNAYKTPLLDDPVFIHPSSV-LFKELPEFVVYQEIVETTKMYMK 994
+ ++ + + +K +T +HPSSV + +++YQE + ++Y++
Sbjct: 1232 IYTKSVDVTEKLACIVET--AQGKAQVHPSSVNRDLQTHGWLLYQEKIRYARVYLR 1285
Score = 131 bits (330), Expect = 3e-30
Identities = 90/291 (30%), Positives = 148/291 (50%), Gaps = 37/291 (12%)
Query: 161 EEEEEEEESESELEEESELDEDPAAEPAEAGVGTTVAPLPPAPAPSSQPVPAGMTVPPPP 220
++++++++ SE + E+ D + + E + + L A +PV
Sbjct: 500 KQQQQQQQQHSENKRENSEDPEESWENLVSDEDFSALSLESANVEDLEPV---------- 549
Query: 221 AAAPPLPRALAKPAVFIPVNRSPEMQEERLKLPILSEEQVIMEAVAEHPIVIVCGETGSG 280
R L + P + ++ +ER +LP+ I+E + H +V+V GETGSG
Sbjct: 550 -------RNLFRKLQSTP--KYQKLLKERQQLPVFKHRDSIVETLKRHRVVVVAGETGSG 600
Query: 281 KTTQVPQFLYEAGFSSEDSI----IGVTEPRRVAAVAMSQRVAKEMNLSQ------RVVS 330
K+TQVP FL E +E I T+PRR++AV+++ RV E+ +
Sbjct: 601 KSTQVPHFLLEDLLLNEWEASKCNIVCTQPRRISAVSLANRVCDELGCENGPGGRNSLCG 660
Query: 331 YQIRYEGNVTEETRIKFMTDGVLLKEIQKDFLLLRYKVVIIDEAHERSVYTDILIGLLSR 390
YQIR E E TR+ + T GVLL+++Q+D LL VI+DE HERSV +D L+ +L
Sbjct: 661 YQIRMESRACESTRLLYCTTGVLLRKLQEDGLLSNVSHVIVDEVHERSVQSDFLLIILKE 720
Query: 391 IVTLRAKRNLPLKLLIMSATLRVEDFTQNPRLFAKPPPVIKVESRQFPVTV 441
I+ R+ L L++MSAT+ E F+ + P++++ R +PV V
Sbjct: 721 ILQKRS----DLHLILMSATVDSEKFS----TYFTHCPILRISGRSYPVEV 763
>gi|38505213 YTH domain containing 2 [Homo sapiens]
Length = 1430
Score = 136 bits (342), Expect = 1e-31
Identities = 102/322 (31%), Positives = 151/322 (46%), Gaps = 43/322 (13%)
Query: 590 VLPLYSLLAPEKQAQVFKPPPEGTRLCVVATNVAETSLTIPGIKYVVDCGKVKKRYYDRV 649
V L+S + Q +V K PP G R +++TN+AETS+T+ + +V+D GKVK++ +D +
Sbjct: 658 VFMLHSNMQTSDQKKVLKNPPAGVRKIILSTNIAETSITVNDVVFVIDSGKVKEKSFDAL 717
Query: 650 TGVSSFRVTWVSQASADQRAGRAGRTEPGHCYRLYSSAVFGDFEQFPPPEITRRPVEDLI 709
V+ ++ W+S+ASA QR GRAGR PG C+RL+S F + +F PE+ R P+++L
Sbjct: 718 NFVTMLKMVWISKASAIQRKGRAGRCRPGICFRLFSRLRFQNMLEFQTPELLRMPLQELC 777
Query: 710 LQMKALNVEKVINFPF-------PTPPSVEALLAAEELLIALGALQPPQKAERVKQLQEN 762
L K L +N P P PP + A ++L + A+ +
Sbjct: 778 LHTKLL---APVNCPIADFLMKAPEPPPALIVRNAVQMLKTIDAMDTWE----------- 823
Query: 763 RLSCPITALGRTMATFPVAPRYAKMLALSRQHGCLPYAITIVASMTVRELFEELDRPAAS 822
+T LG +A PV P KM+ + CL +TI ++ R+ F
Sbjct: 824 ----DLTELGYHLADLPVEPHLGKMVLCAVVLKCLDPILTIACTLAYRDPF--------- 870
Query: 823 DEELTRLKSKRARVAQMKRTWAGQGASLKLGDLMVLLGAVGACEYA---SCTPQFCEANG 879
T+ KRA + KR AG D M LL A A + A FCE N
Sbjct: 871 -VLPTQASQKRAAMLCRKRFTAG-----AFSDHMALLRAFQAWQKARSDGWERAFCEKNF 924
Query: 880 LRYKAMMEIRRLRGQLTTAVNA 901
L M I +R QL + A
Sbjct: 925 LSQATMEIIIGMRTQLLGQLRA 946
Score = 117 bits (293), Expect = 6e-26
Identities = 78/211 (36%), Positives = 121/211 (57%), Gaps = 12/211 (5%)
Query: 237 IPVNRSP-EMQEERLKLPILSEEQVIMEAVAEHPIVIVCGETGSGKTTQVPQFLYEAGFS 295
IPV R E R LP+ +++ I++ + E+ +V++ GETGSGKTTQ+PQFL + F
Sbjct: 177 IPVKRGESEFDSFRQSLPVFEKQEEIVKIIKENKVVLIVGETGSGKTTQIPQFLLDDCFK 236
Query: 296 SE-DSIIGVTEPRRVAAVAMSQRVAKE-MNLSQRVVSYQIRYEGNVTEETRIKFMTDGVL 353
+ I T+PRR+AA+A+++RVA E + + YQIR E V+ +T + F T+GVL
Sbjct: 237 NGIPCRIFCTQPRRLAAIAVAERVAAERRERIGQTIGYQIRLESRVSPKTLLTFCTNGVL 296
Query: 354 LKEIQK-DFLLLRYKVVIIDEAHERSVYTDILIGLLSRIVTLRAKRNLPLKLLIMSATLR 412
L+ + D L VI+DE HER ++D L+ L ++ +++ LKL++ SA L
Sbjct: 297 LRTLMAGDSTLSTVTHVIVDEVHERDRFSDFLLTKLRDLL----QKHPTLKLILSSAALD 352
Query: 413 VEDFTQNPRLFAKPPPVIKVESRQFPVTVHF 443
V F + + PVI ++ R F V F
Sbjct: 353 VNLFIR----YFGSCPVIYIQGRPFEVKEMF 379
>gi|100913206 DEAH (Asp-Glu-Ala-His) box polypeptide 9 [Homo sapiens]
Length = 1270
Score = 133 bits (335), Expect = 9e-31
Identities = 111/425 (26%), Positives = 187/425 (44%), Gaps = 60/425 (14%)
Query: 590 VLPLYSLLAPEKQAQVFKPPPEGTRLCVVATNVAETSLTIPGIKYVVDCGKVKKRYYDRV 649
+LPL+S + E+Q +VF P P G +++TN+AETS+TI + YV+D K K + +
Sbjct: 683 ILPLHSQIPREEQRKVFDPVPVGVTKVILSTNIAETSITINDVVYVIDSCKQKVKLFTAH 742
Query: 650 TGVSSFRVTWVSQASADQRAGRAGRTEPGHCYRLYSSAVFGDFEQFPPPEITRRPVEDLI 709
++++ W S+ + +QR GRAGR PG C+ L S A F E PE+ R P+ ++
Sbjct: 743 NNMTNYATVWASKTNLEQRKGRAGRVRPGFCFHLCSRARFERLETHMTPEMFRTPLHEIA 802
Query: 710 LQMKALNVEKVINFPFPT--PPSVEALLAAEELLIALGALQPPQKAERVKQLQENRLSCP 767
L +K L + + F PP ++A++ AE L L AL +
Sbjct: 803 LSIKLLRLGGIGQFLAKAIEPPPLDAVIEAEHTLRELDALDANDE--------------- 847
Query: 768 ITALGRTMATFPVAPRYAKMLALSRQHGCLPYAITIVASMTVRELFEELDRPAASDEELT 827
+T LGR +A P+ PR+ KM+ + GC+ Y + ++ F E P ++ +
Sbjct: 848 LTPLGRILAKLPIEPRFGKMMIM----GCIFYVGDAICTIAAATCFPE---PFINEGK-- 898
Query: 828 RLKSKRARVAQMKRTWAGQGASLKLGDLMVLLGAVGACEYA-----SCTPQFCEANGLRY 882
R+ + R +AG + D + LL A + A +FCE L
Sbjct: 899 -------RLGYIHRNFAGN----RFSDHVALLSVFQAWDDARMGGEEAEIRFCEHKRLNM 947
Query: 883 KAMMEIRRLRGQL-TTAVNAVCPEAELFVDPKMQPPTESQVTYLRQIVTAGLGDHLARRV 941
+ + QL +N+ PE L ++ + + ++ G+ ++
Sbjct: 948 ATLRMTWEAKVQLKEILINSGFPEDCLLTQVFTNTGPDNNLDVVISLLAFGVYPNVCYHK 1007
Query: 942 QSEEMLEDKWRNAYKTPLLDDPVFIHPSSVL-------FKELPEFVVYQEIVETTKMYMK 994
+ ++L + RNA IH SSV K F V+ E + T + K
Sbjct: 1008 EKRKILTTEGRNA----------LIHKSSVNCPFSSQDMKYPSPFFVFGEKIRTRAISAK 1057
Query: 995 GVSSV 999
G++ V
Sbjct: 1058 GMTLV 1062
Score = 104 bits (259), Expect = 6e-22
Identities = 78/266 (29%), Positives = 138/266 (51%), Gaps = 18/266 (6%)
Query: 186 EPAEAGVGTTVAPLPPAPAPSSQPVPAGMTVPPPPAAAPPLPRALAKPAVFIPVNRSPEM 245
EP++ V P P + + + + P A P K + + + ++
Sbjct: 319 EPSQRQNQVGVVPWSPPQSNWNPWTSSNIDEGPLAFATPEQISMDLKNELMYQLEQDHDL 378
Query: 246 Q---EERLKLPILSEEQVIMEAVAEHPIVIVCGETGSGKTTQVPQFLYEAGFSSE---DS 299
Q +ER LP+ E I+EA++++ +VI+ G TG GKTTQVPQF+ + ++ +
Sbjct: 379 QAILQERELLPVKKFESEILEAISQNSVVIIRGATGCGKTTQVPQFILDDFIQNDRAAEC 438
Query: 300 IIGVTEPRRVAAVAMSQRVAKEMNLSQ-RVVSYQIRYEGNVTE-ETRIKFMTDGVLLKEI 357
I VT+PRR++AV++++RVA E + Y +R+E + I F T GVLL+++
Sbjct: 439 NIVVTQPRRISAVSVAERVAFERGEEPGKSCGYSVRFESILPRPHASIMFCTVGVLLRKL 498
Query: 358 QKDFLLLRYKVVIIDEAHERSVYTDILIGLLSRIVTLRAKRNLPLKLLIMSATLRVEDFT 417
+ + + VI+DE HER + TD L+ +L +V + +++++MSAT+ F
Sbjct: 499 EAGIRGISH--VIVDEIHERDINTDFLLVVLRDVVQAYPE----VRIVLMSATIDTSMFC 552
Query: 418 QNPRLFAKPPPVIKVESRQFPVTVHF 443
+ + P+I+V R +PV +F
Sbjct: 553 E----YFFNCPIIEVYGRTYPVQEYF 574
>gi|20336290 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 2
[Homo sapiens]
Length = 1155
Score = 124 bits (310), Expect = 7e-28
Identities = 104/323 (32%), Positives = 161/323 (49%), Gaps = 40/323 (12%)
Query: 196 VAPLPPAPAPSSQPVPAGMTVPPPPAAAPPLPRALAKPAVFIPVNRSPEMQEERLKLPIL 255
+ PL P S P+ VP A L ++L + + R P QE +LP+
Sbjct: 344 ILPLGKDSGPLSDPITGKPYVPLLEAEEVRLSQSLLE----LWRRRGPVWQEAP-QLPVD 398
Query: 256 SEEQVIMEAVAEHPIVIVCGETGSGKTTQVPQFLYE----AGFSSEDSIIGVTEPRRVAA 311
I+ A+ +HP+V++ G+TG GKTT++PQ L E G + ++I +T+PRR++A
Sbjct: 399 PHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLLLERYVTEGRGARCNVI-ITQPRRISA 457
Query: 312 VAMSQRVAKEMNLS-QRVVSYQIRYEGN-VTEETRIKFMTDGVLLKEIQKDFLLLRYKVV 369
V+++QRV+ E+ S +R V +Q+R E + + F T G+LL+++Q + L V
Sbjct: 458 VSVAQRVSHELGPSLRRNVGFQVRLESKPPSRGGALLFCTVGILLRKLQSNPSLEGVSHV 517
Query: 370 IIDEAHERSVYTDILIGLLSRIVTLRAKRNLPLKLLIMSATLRVEDFTQNPRLFAKPPPV 429
I+DE HER V TD L+ LL + L N L+L++MSAT E F++ + PV
Sbjct: 518 IVDEVHERDVNTDFLLILLKGLQRL----NPALRLVLMSATGDNERFSR----YFGGCPV 569
Query: 430 IKVESRQFPVTVHFNK-------------RTPLEDYSGECFRK-------VCKIHRMLPA 469
IKV +PV H+ + R + EC V I
Sbjct: 570 IKVPGFMYPVKEHYLEDILAKLGKHQYLHRHRHHESEDECALDLDLVTDLVLHIDARGEP 629
Query: 470 GGILVFLTGQAEVHALCRRLRKA 492
GGIL FL G E+ + +RL++A
Sbjct: 630 GGILCFLPGWQEIKGVQQRLQEA 652
Score = 121 bits (303), Expect = 4e-27
Identities = 95/294 (32%), Positives = 137/294 (46%), Gaps = 42/294 (14%)
Query: 558 EEEGALDSDLDLDL----GDGGQDGG---------------EQPDASLPLH-----VLPL 593
E+E ALD DL DL G+ GG ++ +L +H +LP+
Sbjct: 606 EDECALDLDLVTDLVLHIDARGEPGGILCFLPGWQEIKGVQQRLQEALGMHESKYLILPV 665
Query: 594 YSLLAPEKQAQVFKPPPEGTRLCVVATNVAETSLTIPGIKYVVDCGKVKKRYYDRVTGVS 653
+S + Q +F+ PP G R V+ATN+AETS+TI I +VVD G K+ YD T VS
Sbjct: 666 HSNIPMMDQKAIFQQPPVGVRKIVLATNIAETSITINDIVHVVDSGLHKEERYDLKTKVS 725
Query: 654 SFRVTWVSQASADQRAGRAGRTEPGHCYRLYSSAVFGDFEQFPPPEITRRPVEDLILQMK 713
WVS+A+ QR GRAGR + G Y L+ + F PEI R P+E+L+LQ K
Sbjct: 726 CLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMVPFQVPEILRTPLENLVLQAK 785
Query: 714 ALNVEK-VINF--PFPTPPSVEALLAAEELLIALGALQPPQKAERVKQLQENRLSCPITA 770
EK + F P+++A+ A LL +G L + +T
Sbjct: 786 IHMPEKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVLDQREY---------------LTT 830
Query: 771 LGRTMATFPVAPRYAKMLALSRQHGCLPYAITIVASMTVRELFEELDRPAASDE 824
LG+ +A PR AK + L+ CL + +V+ +T L A D+
Sbjct: 831 LGQRLAHISTDPRLAKAIVLAAIFRCLHPLLVVVSCLTRDPFSSSLQNRAEVDK 884
>gi|20336294 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 1
[Homo sapiens]
Length = 1194
Score = 124 bits (310), Expect = 7e-28
Identities = 104/323 (32%), Positives = 161/323 (49%), Gaps = 40/323 (12%)
Query: 196 VAPLPPAPAPSSQPVPAGMTVPPPPAAAPPLPRALAKPAVFIPVNRSPEMQEERLKLPIL 255
+ PL P S P+ VP A L ++L + + R P QE +LP+
Sbjct: 383 ILPLGKDSGPLSDPITGKPYVPLLEAEEVRLSQSLLE----LWRRRGPVWQEAP-QLPVD 437
Query: 256 SEEQVIMEAVAEHPIVIVCGETGSGKTTQVPQFLYE----AGFSSEDSIIGVTEPRRVAA 311
I+ A+ +HP+V++ G+TG GKTT++PQ L E G + ++I +T+PRR++A
Sbjct: 438 PHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLLLERYVTEGRGARCNVI-ITQPRRISA 496
Query: 312 VAMSQRVAKEMNLS-QRVVSYQIRYEGN-VTEETRIKFMTDGVLLKEIQKDFLLLRYKVV 369
V+++QRV+ E+ S +R V +Q+R E + + F T G+LL+++Q + L V
Sbjct: 497 VSVAQRVSHELGPSLRRNVGFQVRLESKPPSRGGALLFCTVGILLRKLQSNPSLEGVSHV 556
Query: 370 IIDEAHERSVYTDILIGLLSRIVTLRAKRNLPLKLLIMSATLRVEDFTQNPRLFAKPPPV 429
I+DE HER V TD L+ LL + L N L+L++MSAT E F++ + PV
Sbjct: 557 IVDEVHERDVNTDFLLILLKGLQRL----NPALRLVLMSATGDNERFSR----YFGGCPV 608
Query: 430 IKVESRQFPVTVHFNK-------------RTPLEDYSGECFRK-------VCKIHRMLPA 469
IKV +PV H+ + R + EC V I
Sbjct: 609 IKVPGFMYPVKEHYLEDILAKLGKHQYLHRHRHHESEDECALDLDLVTDLVLHIDARGEP 668
Query: 470 GGILVFLTGQAEVHALCRRLRKA 492
GGIL FL G E+ + +RL++A
Sbjct: 669 GGILCFLPGWQEIKGVQQRLQEA 691
Score = 121 bits (303), Expect = 4e-27
Identities = 95/294 (32%), Positives = 137/294 (46%), Gaps = 42/294 (14%)
Query: 558 EEEGALDSDLDLDL----GDGGQDGG---------------EQPDASLPLH-----VLPL 593
E+E ALD DL DL G+ GG ++ +L +H +LP+
Sbjct: 645 EDECALDLDLVTDLVLHIDARGEPGGILCFLPGWQEIKGVQQRLQEALGMHESKYLILPV 704
Query: 594 YSLLAPEKQAQVFKPPPEGTRLCVVATNVAETSLTIPGIKYVVDCGKVKKRYYDRVTGVS 653
+S + Q +F+ PP G R V+ATN+AETS+TI I +VVD G K+ YD T VS
Sbjct: 705 HSNIPMMDQKAIFQQPPVGVRKIVLATNIAETSITINDIVHVVDSGLHKEERYDLKTKVS 764
Query: 654 SFRVTWVSQASADQRAGRAGRTEPGHCYRLYSSAVFGDFEQFPPPEITRRPVEDLILQMK 713
WVS+A+ QR GRAGR + G Y L+ + F PEI R P+E+L+LQ K
Sbjct: 765 CLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMVPFQVPEILRTPLENLVLQAK 824
Query: 714 ALNVEK-VINF--PFPTPPSVEALLAAEELLIALGALQPPQKAERVKQLQENRLSCPITA 770
EK + F P+++A+ A LL +G L + +T
Sbjct: 825 IHMPEKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVLDQREY---------------LTT 869
Query: 771 LGRTMATFPVAPRYAKMLALSRQHGCLPYAITIVASMTVRELFEELDRPAASDE 824
LG+ +A PR AK + L+ CL + +V+ +T L A D+
Sbjct: 870 LGQRLAHISTDPRLAKAIVLAAIFRCLHPLLVVVSCLTRDPFSSSLQNRAEVDK 923
>gi|166851804 tudor domain containing 9 [Homo sapiens]
Length = 1382
Score = 123 bits (309), Expect = 9e-28
Identities = 100/356 (28%), Positives = 163/356 (45%), Gaps = 33/356 (9%)
Query: 588 LHVLPLYSLLAPEKQAQVFKPPPEGTRLCVVATNVAETSLTIPGIKYVVDCGKVKKRYYD 647
L V PL+S +A E+Q VF P G R +++TN+AE+S+T+P +KYV+D + D
Sbjct: 413 LQVYPLHSSVALEEQNNVFLSPVPGYRKIILSTNIAESSVTVPDVKYVIDFCLTRTLVCD 472
Query: 648 RVTGVSSFRVTWVSQASADQRAGRAGRTEPGHCYRLYSSAVF-GDFEQFPPPEITRRPVE 706
T S R++W S+ S +QR GRAGR G+CYRL + PE+ R P+
Sbjct: 473 EDTNYQSLRLSWASKTSCNQRKGRAGRVSRGYCYRLVHKDFWDNSIPDHVVPEMLRCPLG 532
Query: 707 DLILQMKALNV--EKVINFPFPTPPSVEALLAAEELLIALGALQPPQKAERVKQLQENRL 764
IL++K L++ + + +PP + + LL +GAL + E EN
Sbjct: 533 STILKVKLLDMGEPRALLATALSPPGLSDIERTILLLKEVGALAVSGQRE-----DENPH 587
Query: 765 SCPITALGRTMATFPVAPRYAKMLALSRQHGCLPYAITIVASMTVRELF-----EELDRP 819
+T LGR +A PV + K++ L GCL + I A+++++ F + LD
Sbjct: 588 DGELTFLGRVLAQLPVNQQLGKLIVLGHVFGCLDECLIIAAALSLKNFFAMPFRQHLDGY 647
Query: 820 AASDEELTRLKSKRARVAQMKRTWAGQGASLKLGDLMVLLGAVGACEYASCTPQFCEANG 879
KS + + +TW A + G+L Y + N
Sbjct: 648 RNKVNFSGSSKSDCIALVEAFKTWK---ACRQTGEL----------RYPKDELNWGRLNY 694
Query: 880 LRYKAMMEIRRLRGQLTTAVNAVCPEAELFVD---PKMQPPTESQVTYLRQIVTAG 932
++ K + E+ L +L T ++ + + VD P M + ++ Q+V AG
Sbjct: 695 IQIKRIREVAELYEELKTRIS----QFNMHVDSRRPVMDQEYIYKQRFILQVVLAG 746
Score = 97.1 bits (240), Expect = 9e-20
Identities = 77/268 (28%), Positives = 132/268 (49%), Gaps = 36/268 (13%)
Query: 174 EEESELDEDPAAEPAEAGVGTTVAPLPPAPA--------------------PSSQPVPAG 213
EE D P A PA AP PA A +Q +
Sbjct: 39 EEVQRQDVAPGAGPAAQAPALAQAPARPAAAFERSLSQRSSEVEYINKYRQLEAQELDVC 98
Query: 214 MTVPPPPAAAPPLPRALAKPAVFIP--VNRSPEMQEERLKLPILSEEQVIMEAVAEHPIV 271
+V P P A IP + P+ LPI ++ ++ + + +V
Sbjct: 99 RSVQPTSGPGPRPSLAKLSSVTCIPGTTYKYPD-------LPISRYKEEVVSLIESNSVV 151
Query: 272 IVCGETGSGKTTQVPQFLYE--AGFSSEDSIIGVTEPRRVAAVAMSQRVAKEMNLSQR-V 328
I+ G TGSGK+TQ+PQ++ + S+ SI+ VT+PR++ A ++++ ++KE + V
Sbjct: 152 IIHGATGSGKSTQLPQYILDHYVQRSAYCSIV-VTQPRKIGASSIARWISKERAWTLGGV 210
Query: 329 VSYQIRYEGNVTEETRIKFMTDGVLLKEIQKDFLLLRYKVVIIDEAHERSVYTDILIGLL 388
V YQ+ E TE+TR+ +MT GVLL++I L+ + +IIDE HER+ D L+ ++
Sbjct: 211 VGYQVGLEKIATEDTRLIYMTTGVLLQKIVSAKSLMEFTHIIIDEVHERTEEMDFLLLVV 270
Query: 389 SRIVTLRAKRNLPLKLLIMSATLRVEDF 416
+++ ++ +K+++MSAT+ ++F
Sbjct: 271 RKLLRTNSRF---VKVVLMSATISCKEF 295
>gi|20336300 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 32 [Homo
sapiens]
Length = 743
Score = 108 bits (271), Expect = 2e-23
Identities = 79/250 (31%), Positives = 132/250 (52%), Gaps = 13/250 (5%)
Query: 240 NRSPEMQEERLKLPILSEEQVIMEAVAEHPIVIVCGETGSGKTTQVPQFLYEAGFSSEDS 299
+R ++ +ER LPI E+ ME + ++ IVIV G+ GK+ QVPQ+ E S
Sbjct: 50 SRYYKLLKEREDLPIWKEKYSFMENLLQNQIVIVSGDAKCGKSAQVPQWCAEYCLSIHYQ 109
Query: 300 IIGV--TEPRRVAAVAMSQRVAKEMNLS-QRVVSYQIRYEGNVTEETRIKFMTDGVLLKE 356
GV T+ + V ++ RVA EM+++ V Y I +E T ET +++ TD +L +E
Sbjct: 110 HGGVICTQVHKQTVVQLALRVADEMDVNIGHEVGYVIPFENCCTNETILRYCTDDMLQRE 169
Query: 357 IQKDFLLLRYKVVIIDEAHERSVYTDILIGLLSRIVTLRAKRNLPLKLLIMSATLRVEDF 416
+ + L Y V+I+D+ HERS+ TD+L+GLL ++ R + LKL+I S+ +
Sbjct: 170 MMSNPFLGSYGVIILDDIHERSIATDVLLGLLKDVLLARPE----LKLIINSSPHLISKL 225
Query: 417 TQNPRLFAKPPPVIKVESRQFPVTVHFNKRTPLEDYSGECFRKVCKIHRMLPAGGILVFL 476
+ PVI+V+++ PV V + + + R + +IH G I+VFL
Sbjct: 226 NS----YYGNVPVIEVKNKH-PVEVVYLSEAQKDSFE-SILRLIFEIHHSGEKGDIVVFL 279
Query: 477 TGQAEVHALC 486
+ ++ +C
Sbjct: 280 ACEQDIEKVC 289
Score = 71.2 bits (173), Expect = 5e-12
Identities = 96/450 (21%), Positives = 181/450 (40%), Gaps = 66/450 (14%)
Query: 588 LHVLPLYSLLAPEKQAQVFKPPPEGTRLC-------VVATNVAETSLTIPGIKYVVDCGK 640
L V+PLY P+++ +FKP E + C V+ T+ E + +++V+D G
Sbjct: 305 LVVVPLY----PKEKCSLFKPLDETEKRCQVYQRRVVLTTSSGEFLIWSNSVRFVIDVGV 360
Query: 641 VKKRYYDRVTGVSSFRVTWVSQASADQRAGRAGRTEPGHCYRLYSSAVFG-DFEQFPPPE 699
+++ Y+ +S + +SQ+ A+ R G + G + LY+ D P E
Sbjct: 361 ERRKVYNPRIRANSLVMQPISQSQAEIRKQILGSSSSGKFFCLYTEEFASKDMTPLKPAE 420
Query: 700 ITRRPVEDLILQMKALNVEKVINFPFPTPPSVEALLAAEELLIALGALQPPQKAERVKQL 759
+ + ++L MK +++ + + F P+ E+L+ A E L L AL
Sbjct: 421 MQEANLTSMVLFMKRIDIAGLGHCDFMNRPAPESLMQALEDLDYLAALD----------- 469
Query: 760 QENRLSCPITALGRTMATFPVAPRYAKMLALSRQHGCLPYAITIVASMTVRELFEELDRP 819
+ LS G M+ FP+ P+ +K + S + C+ +TI A +T F + P
Sbjct: 470 NDGNLS----EFGIIMSEFPLDPQLSKSILASCEFDCVDEVLTIAAMVTAPNCFSHV--P 523
Query: 820 AASDEEL-----TRLKSKRARVAQMKRTWAGQGASLKLGDLMVLLGAVGACEYASCTPQF 874
++E T L + + A Q +L + EY C ++
Sbjct: 524 HGAEEAALTCWKTFLHPEGDHFTLISIYKAYQDTTLN-----------SSSEY--CVEKW 570
Query: 875 CEANGLRYKAMMEIRRLRGQLTTAVNAVCPEAELFVDPKMQPP--TESQVTYLRQIVTAG 932
C L A+ +R +L + + EL P +P ++ +++ + +G
Sbjct: 571 CRDYFLNCSALRMADVIRAELLEIIKRI----EL---PYAEPAFGSKENTLNIKKALLSG 623
Query: 933 LGDHLARRVQSEEMLEDKWRNAYKTPLLDDPVFIHPSS--VLFKELPEFVVYQEIVETTK 990
+AR V Y +HP S + K++PE+V++ + +
Sbjct: 624 YFMQIARDVDGS--------GNYLMLTHKQVAQLHPLSGYSITKKMPEWVLFHKFSISEN 675
Query: 991 MYMKGVSSVEVQWIPALLPSYCQFDKPLEE 1020
Y++ S + + L+P Y + P E
Sbjct: 676 NYIRITSEISPELFMQLVPQYYFSNLPPSE 705
>gi|163914394 DEAQ box polypeptide 1 (RNA-dependent ATPase) [Homo
sapiens]
Length = 717
Score = 92.8 bits (229), Expect = 2e-18
Identities = 79/261 (30%), Positives = 130/261 (49%), Gaps = 19/261 (7%)
Query: 240 NRSPEMQEERLKLPILSEEQVIMEAVAEHP--IVIVCGETGSGKTTQVPQFLYEAGFSS- 296
+R E+ ++R LPI + +E + +P +V+V GE GSGK+TQ+PQ+ E +
Sbjct: 33 SRYYELLKQRQALPIWAARFTFLEQLESNPTGVVLVSGEPGSGKSTQIPQWCAEFALARG 92
Query: 297 -EDSIIGVTEPRRVAAVAMSQRVAKEMNLSQ-RVVSYQIRYEGNVTEETRIKFMTDGVLL 354
+ + VT+P +AA +++ RVA EM+L+ V Y I E T ++F D +LL
Sbjct: 93 FQKGQVTVTQPYPLAARSLALRVADEMDLTLGHEVGYSIPQEDCTGPNTLLRFCWDRLLL 152
Query: 355 KEIQKDFLLLRYKVVIIDEAHERSVYTDILIGLLSRIVTLRAKRNLPLKLLIMSATLRVE 414
+E+ + V+++DEA ERSV +D L GLL LP L ++ T
Sbjct: 153 QEVASTRGTGAWGVLVLDEAQERSVASDSLQGLLQD----ARLEKLPGDLRVVVVT---- 204
Query: 415 DFTQNPRL--FAKPPPVIKV--ESRQFPVTVHFNKRTPLEDYSGECFRKVCKIHRMLPAG 470
D P+L F PP++ + E + P ++++ P D + V ++ R G
Sbjct: 205 DPALEPKLRAFWGNPPIVHIPREPGERPSPIYWDTIPP--DRVEAACQAVLELCRKELPG 262
Query: 471 GILVFLTGQAEVHALCRRLRK 491
+LVFL + E+ C L +
Sbjct: 263 DVLVFLPSEEEISLCCESLSR 283
Score = 77.8 bits (190), Expect = 6e-14
Identities = 82/313 (26%), Positives = 138/313 (44%), Gaps = 42/313 (13%)
Query: 586 LPLHVLPLYSLLAPEKQAQVFKPPPEGTRLCVVATNVAETSLTIPGIKYVVDCG-KVKKR 644
LP VLPL+ QA V++ R VV +A+ S ++P I++V+D G +++
Sbjct: 293 LPPRVLPLHPDCGRAVQA-VYEDMD--ARKVVVTHWLADFSFSLPSIQHVIDSGLELRSV 349
Query: 645 YYDRVTGVSSFRVTW-VSQASADQRAGRAGRTEPGHCYRLYSSAVFG-DFEQFPPPEITR 702
Y R+ + F+V +S+ A+ R RA PG C LY + + P P +
Sbjct: 350 YNPRIR--AEFQVLRPISKCQAEARRLRARGFPPGSCLCLYPKSFLELEAPPLPQPRVCE 407
Query: 703 RPVEDLILQMKALNVEKVINFPFPTPPSVEALLAAEELLIALGALQPPQKAERVKQLQEN 762
+ L+L +K + + F P+ EAL+ A E L L AL
Sbjct: 408 ENLSSLVLLLKRRQIAEPGECHFLDQPAPEALMQALEDLDYLAALDDDGD---------- 457
Query: 763 RLSCPITALGRTMATFPVAPRYAKMLALSRQHGCLPYAITIVASMTVRELFEELDRPAAS 822
++ LG ++ FP+AP AK L S + C+ +T+ A +T F RP S
Sbjct: 458 -----LSDLGVILSEFPLAPELAKALLASCEFDCVDEMLTLAAMLTAAPGF---TRPPLS 509
Query: 823 DEELTRLKSKRARVAQMKRTWAGQGASLKLGDLMVLLGAVGACEYASCTPQFCEANGLRY 882
EE ++ ++ T + +++ + + GA A +C+A GL +
Sbjct: 510 AEEAALRRA-------LEHTDGDHSSLIQVYEAFIQSGADEA---------WCQARGLNW 553
Query: 883 KAMMEIRRLRGQL 895
A+ + +LRG+L
Sbjct: 554 AALCQAHKLRGEL 566
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 58.2 bits (139), Expect = 5e-08
Identities = 34/83 (40%), Positives = 45/83 (54%), Gaps = 8/83 (9%)
Query: 160 EEEEEEEEESESELEEESELDED--PAAEPAEAGVGT------TVAPLPPAPAPSSQPVP 211
E++EEEE++ E E +EE + E+ PAAE EA + +P PP P PS+ P P
Sbjct: 367 EKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPP 426
Query: 212 AGMTVPPPPAAAPPLPRALAKPA 234
PPPP + PPLP PA
Sbjct: 427 PLCPPPPPPVSPPPLPSPPPPPA 449
Score = 32.3 bits (72), Expect = 2.7
Identities = 24/75 (32%), Positives = 33/75 (44%), Gaps = 14/75 (18%)
Query: 179 LDEDPAAEPAEAGVGTTVAPLPPAPAPSSQPVPAGMTVPPPPAAAPPLPRALAKPAVFIP 238
+DEDP P V+P+ P +S PVP PA P PRA P+ +P
Sbjct: 547 MDEDPPKPPK-----VEVSPVLRPPITTSPPVPQ------EPAPVPSPPRAPTPPSTPVP 595
Query: 239 VNRSPEMQEERLKLP 253
+ PE + L+ P
Sbjct: 596 L---PEKRRSILREP 607
>gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [Homo
sapiens]
Length = 1251
Score = 54.7 bits (130), Expect = 5e-07
Identities = 55/219 (25%), Positives = 94/219 (42%), Gaps = 15/219 (6%)
Query: 59 TKAPPLSKKEKKPLTKKEKKVLQKILEQKEKKSQRAEMLQKLSEVQASEAEMRLFYTTSK 118
T+ P ++E K + K ++ L +I E+KE + + E ++ E + +E + S+
Sbjct: 327 TEVVPAYEEENKAVEKMPRE-LSRIEEEKEDEEEEEEEEEEEEEEEVTEVLLDSC-VVSQ 384
Query: 119 LGTGNRMYHTKEKADEVVAPGQEKISSLSGAHRKRRRWPSAEEEEEE--EEESESELEEE 176
+G G ++E + +K+ G K+ A+EE EE EEE+E E ++
Sbjct: 385 VGVGQ----SEEDGTRPQSTSDQKLWEEVGEEAKKEAEEKAKEEAEEVAEEEAEKEPQDW 440
Query: 177 SELDEDPAAEPAEAGVGTTVAPLPPAPAPSSQPVPAG--MTVPPPPAAAPPLPRALAKPA 234
+E E+P AE A G P + M PP+ P P
Sbjct: 441 AETKEEPEAEAEAASSGVPATKQHPEVQVEDTDADSCPLMAEENPPSTVLPPPSPAKSDT 500
Query: 235 VFIPVNRSPEMQEERLKLPILSEEQVIMEAV--AEHPIV 271
+ +P + S R KLP +E ++A+ AE P+V
Sbjct: 501 LIVPSSAS---GTHRKKLPSEDDEAEELKALSPAESPVV 536
Score = 35.0 bits (79), Expect = 0.41
Identities = 45/174 (25%), Positives = 71/174 (40%), Gaps = 14/174 (8%)
Query: 19 GPSKGPPEPP--PVQLELEDKDTLKGVDASNALVLPGKKKKKTKAPPLSKKEKKP---LT 73
GP E P P + L+ K+ K A PG + + + PP + L
Sbjct: 204 GPKLQARETPSLPTPIPLQPKEEPKEAPAPEPQ--PGSQAQTSSLPPTRDPARLVAWVLH 261
Query: 74 KKEKKVLQKILEQK----EKKSQRAEMLQKLSEVQASEAEMRLFYTTSK--LGTGNRMYH 127
+ E + Q +L K E S +Q +S + + E L + ++
Sbjct: 262 RLEMALPQPVLHGKIGEQEPDSPGICDVQTISILPGGQVEPDLVLEEVEPPWEDAHQDVS 321
Query: 128 TKEKADEVVAPGQEKISSLSGAHRKRRRWPSAEEEEEEEEESESELEEESELDE 181
T + EVV +E+ ++ R+ R +E+EEEEEE E E EEE E+ E
Sbjct: 322 TSPQGTEVVPAYEEENKAVEKMPRELSRIEEEKEDEEEEEEEEEE-EEEEEVTE 374
Score = 34.7 bits (78), Expect = 0.54
Identities = 46/203 (22%), Positives = 80/203 (39%), Gaps = 36/203 (17%)
Query: 67 KEKKPLTKKEKKVLQKILEQKEKKS-----QRAEMLQKLSEVQASEAEMRLFYTTSKLGT 121
+ +K L KK +++L+ + KE+KS RA + + A +M K
Sbjct: 1071 ESQKLLRKKARRMLRSNNKPKEEKSVLILPPRAGTPKLFNAALAMTGKMG-----GKGAK 1125
Query: 122 GNRMYHTKEKADEVVAPGQEKISSLSGAHRKRRRWPSAEEEEEEEEESESELEEESELDE 181
G ++ H + + E+ A L A ++ +E E+ + S+ EE
Sbjct: 1126 GGKLAHLRARLKELAA--------LEAAAKQ-------QELVEQAKSSQDVKGEEGSAAP 1170
Query: 182 DPAAEPAEAGVGTTVAPLPPAPAPSSQPVPAGMTVPPPPAAAPPL-----PRALAKPAVF 236
D P EA PPAP +P + + PPP + P P + +V
Sbjct: 1171 DQHTHPKEAATD------PPAPRTPPEPPGSPPSSPPPASLGRPEGEEEGPAEPEEHSVR 1224
Query: 237 IPVNRSPEMQEERLKLPILSEEQ 259
I ++ PE E+ L + + E +
Sbjct: 1225 ICMSPGPEPGEQILSVKMPEERE 1247
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 53.1 bits (126), Expect = 1e-06
Identities = 63/261 (24%), Positives = 107/261 (40%), Gaps = 41/261 (15%)
Query: 5 RRRYNIKGRQQAGPGPSKGPPEPPPVQLELEDKDTLKGVDASNALVLPGKKKKKTKAPPL 64
R R K +++ + E ++ +L +K+ N + KK ++ +
Sbjct: 421 REREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAE 480
Query: 65 SKKEKKPLTKKEKKVLQKILE-----QKEKKSQRAEMLQKLSEVQASEAEMRLFYTTSKL 119
++E++ KE K L++ LE + + K R LQK ++ E EM K
Sbjct: 481 REEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQK--RLRDREKEMEADERDRK- 537
Query: 120 GTGNRMYHTKEKADEVVA---------PGQEKISSLSGAHRKR----RRWPSAEEEEEEE 166
KE+ +E+ P E A R+R ++ P +EEEEEE+
Sbjct: 538 -------REKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEK 590
Query: 167 EESESELEEESELDEDPAAEPAEAGVGTTVAPLPPAPAPSSQPVPAGMTVPPPPAAAPPL 226
+E E + EE E +E+P +P + T+ P+ AP+ SS +G P P P
Sbjct: 591 QEKEEKREEPMEEEEEPEQKPC---LKPTLRPISSAPSVSS---ASGNATPNTPGDESPC 644
Query: 227 PRALAKPAVFIPVNRSPEMQE 247
+ IP SP+ Q+
Sbjct: 645 -------GIIIPHENSPDQQQ 658
Score = 31.2 bits (69), Expect = 6.0
Identities = 34/140 (24%), Positives = 53/140 (37%), Gaps = 21/140 (15%)
Query: 52 PGKKKKKTKAP-----PLSKKEKKPLTKKEKKVLQKILEQKEKKSQRAEMLQKLSEVQAS 106
P KKKK+ K P++ PL KE + E + + +++ +
Sbjct: 233 PRKKKKEKKEDIFRRFPVAPLIPYPLITKED------INAIEMEEDKRDLISR------- 279
Query: 107 EAEMRLFYTTSKLGTGNRMYHTKEKADEVVAPGQEKISSLSGAHRKRRRWPSAEEEEEEE 166
E+ F T K + KE+ E+ +E+ +R R E E E E
Sbjct: 280 --EISKFRDTHKKLEEEKGKKEKER-QEIEKERRERERERERERERRERERERERERERE 336
Query: 167 EESESELEEESELDEDPAAE 186
+E E E E E + D D E
Sbjct: 337 KEKERERERERDRDRDRTKE 356
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 52.4 bits (124), Expect = 3e-06
Identities = 53/203 (26%), Positives = 83/203 (40%), Gaps = 26/203 (12%)
Query: 47 NALVLPGKKKKKTKAPPLSKKEKKPLTK---KEKKVLQKILEQKEKKSQRAEMLQKLSEV 103
NA P +++ +A P+ KKEKK + KEK L + K+++S A +LS
Sbjct: 395 NAGGSPAPVRRRPEASPVQKKEKKDKERENEKEKSALARERSLKKRQSLPASPRARLSAS 454
Query: 104 QASEAEMRLFYTTSKLGTGNRMYHTKEKADEVVAPGQE--------KISSLSGAHRKRRR 155
ASE + + ++ + + +H PG + ++ S R RR+
Sbjct: 455 TASELSPK---SKARPSSPSTSWHRPASPCPSPGPGHTLPPKPPSPRGTTASPKGRVRRK 511
Query: 156 WPSAEEEEEEEEESESELEEESELDEDPAAEPAEAGVGTTVAPLPPAPAPSSQPVPAGMT 215
EE +E S + E++S+ + E A AP PAP+P+ P PA
Sbjct: 512 ------EEAKESPSAAGPEDKSQSKRRASNEKESA------APASPAPSPAPSPTPAPPQ 559
Query: 216 VPPPPAAAPPLPRALAKPAVFIP 238
PPA P L P P
Sbjct: 560 KEQPPAETPTDAAVLTSPPAPAP 582
Score = 36.6 bits (83), Expect = 0.14
Identities = 38/175 (21%), Positives = 71/175 (40%), Gaps = 30/175 (17%)
Query: 16 AGPGPSKGP-PEPPPVQLELEDKDTLKGVDASNALVLPGKKKKKTKAPPLSKKEKKPLTK 74
A P PS P P P P Q E +T ++A VL APP++ + T
Sbjct: 543 ASPAPSPAPSPTPAPPQKEQPPAET-----PTDAAVLTSPP---APAPPVTPSKPMAGTT 594
Query: 75 KEKKVLQKILEQKEKKSQRAEMLQKLSEVQASEAEMRLFYTTSKLGTGNRMYHTKEKADE 134
++ + + E++ + ++ E ++ +QA ++ ++ A E
Sbjct: 595 DREEATRLLAEKRRQAREQREREEQERRLQAER---------------DKRMREEQLARE 639
Query: 135 VVAPGQEKISSLSGAHRKRRRWPSAEEEEEEEEESESELEEESELDEDPAAEPAE 189
A + + A +RR A E+ + E+E + L+++ E E + E AE
Sbjct: 640 AEARAERE------AEARRREEQEAREKAQAEQEEQERLQKQKEEAEARSREEAE 688
Score = 31.2 bits (69), Expect = 6.0
Identities = 22/89 (24%), Positives = 47/89 (52%), Gaps = 4/89 (4%)
Query: 55 KKKKTKAPPLSKKE-KKPLTKKEKKVLQKILEQKEKKSQRAEMLQKLSEVQASEAEMRLF 113
+K+K +A S++E ++ ++EK Q+ E++E++ + E++++ + + SE + +
Sbjct: 673 QKQKEEAEARSREEAERQRLEREKHFQQQEQERQERRKRLEEIMKRTRKSEVSETKQK-- 730
Query: 114 YTTSKLGTGNRMYHTKEKADEVVAPGQEK 142
SK N KA E +PG +K
Sbjct: 731 -QDSKEANANGSSPEPVKAVEARSPGLQK 758
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 50.8 bits (120), Expect = 7e-06
Identities = 59/258 (22%), Positives = 103/258 (39%), Gaps = 40/258 (15%)
Query: 3 KLRRRYNIKGRQQAGPGPSKGPPEPPPVQLELEDKDTLKGVDASNALVLPGKKKKKTKAP 62
K +++ K +++ EPPP K T K +++ + K+K P
Sbjct: 544 KEKKKEKHKRKEEVEENKKSKAKEPPP-------KKTKKNNSSNSNVSKKEPAPMKSKPP 596
Query: 63 PLSKKEK----KPLTKKEKKVLQKILEQK--EKKSQRAEMLQKL--SEVQASEAEMRLFY 114
P + E+ KP++ +EK+ L + + EK + ++Q S ++ E+ + +
Sbjct: 597 PTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDF 656
Query: 115 TTSKLGTGNRM--YHT-------KEKADEV-VAPGQEKISSLSGAHRKRRRWPSAEEEEE 164
T K T + Y T K +A++V V G K+ S + + S+E
Sbjct: 657 ETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESES----SSESSSS 712
Query: 165 EEEESESELEEESELDEDPAAEPA-----------EAGVGTTVAPLPPAPAPSSQPVPAG 213
+ E+SE+E+ +S+ P E +A P PP P P P
Sbjct: 713 DSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQ 772
Query: 214 MTVPPPPAAAPPLPRALA 231
PPPP P +P+ A
Sbjct: 773 QQQPPPPPPPPSMPQQAA 790
Score = 32.7 bits (73), Expect = 2.1
Identities = 19/64 (29%), Positives = 24/64 (37%), Gaps = 10/64 (15%)
Query: 195 TVAPLPPAPAPSSQPVPAGMTVPPPPAAAPPLPRALAK----------PAVFIPVNRSPE 244
T P+PP P P P P + PP AA P P K P P++ P
Sbjct: 249 TPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPS 308
Query: 245 MQEE 248
+ E
Sbjct: 309 LPPE 312
Score = 32.0 bits (71), Expect = 3.5
Identities = 19/56 (33%), Positives = 24/56 (42%), Gaps = 1/56 (1%)
Query: 198 PLPPAPAPSSQPVPAGMTVPPPPAAAPPLPRALAKPAVFIPVNRSPEMQEERLKLP 253
PLPP P PS Q PPPP P P+ +P PV+ P ++ P
Sbjct: 957 PLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPP-RPVHLQPMQFSTHIQQP 1011
Score = 31.2 bits (69), Expect = 6.0
Identities = 15/55 (27%), Positives = 31/55 (56%)
Query: 479 QAEVHALCRRLRKAFPPSRARPQEKDDDQKDSVEEMRKFKKSRARAKKARAEVLP 533
Q ++ A+ +L P + +P++K+ D+K+ +E K K+ KK++A+ P
Sbjct: 515 QEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPP 569
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 50.4 bits (119), Expect = 1e-05
Identities = 63/246 (25%), Positives = 104/246 (42%), Gaps = 31/246 (12%)
Query: 44 DASNALVLPGKKKKKTKAPPLSKKEKKPLTKKEKKVLQKILEQKEKKSQRAEMLQKLSEV 103
+ S+ +P K +K KAPP K KKP+ +K +K +++ E+K + ++ E+ +K+
Sbjct: 9158 EESHERKVPAKVPEK-KAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQ 9216
Query: 104 QAS---------EAEMRLFYTTSKLGTGNRMY---HTKEKADEVVAPGQEKISSLSGAHR 151
+ S E ++ +T + + +M+ HT+E+ V Q++I + H
Sbjct: 9217 KPSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIH- 9275
Query: 152 KRRRWPSAEEEEEEEEESESELEEESELDEDPAAEPAEAGVGTTVAPLPPAPAPSSQPVP 211
A + E EL E+ E+ A P V P P P +PVP
Sbjct: 9276 ------VAISKRVEPPPKVPELPEK-PAPEEVAPVPIPKKV---EPPAPKVPEVPKKPVP 9325
Query: 212 -AGMTVPPP---PAAAPPLPRALAKPAVFIPVNRSPEMQEERLKLPILSEEQVIMEAVAE 267
VP P PAA P +P KP +P + P ++ + P +V V E
Sbjct: 9326 EEKKPVPVPKKEPAAPPKVPEVPKKP---VPEEKIPVPVAKKKEAPPAKVPEVQKGVVTE 9382
Query: 268 HPIVIV 273
I IV
Sbjct: 9383 EKITIV 9388
Score = 46.2 bits (108), Expect = 2e-04
Identities = 60/263 (22%), Positives = 100/263 (38%), Gaps = 34/263 (12%)
Query: 14 QQAGPGPSKGPPEPPPVQLELEDKDTLKGVDASNALVLPGKKKKKTKAPPLSKKEKKPLT 73
++ P P K PPP ++ K P ++K P++KK P
Sbjct: 9409 EERKPVPRKEEEVPPPPKVPALPKK-------------PVPEEKVAVPVPVAKKAPPPRA 9455
Query: 74 KKEKKVL--QKILEQKEKKSQRAEMLQKLSEVQASEAEMRLFYTTSKLGTGNRMYHTKEK 131
+ KK + +K +EK S +++ + S AE Y+ + G +Y +E+
Sbjct: 9456 EVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVS-AEEEWSYSEEEEGVSISVYREEER 9514
Query: 132 ADEVVA----------PGQEKISSLSGAHRKRRRWPSAEEEEEEEEESESELEEESELDE 181
+E A P + + KR AE E +E++ + + ++++E
Sbjct: 9515 EEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEKKIVLKPKIPAKIEE 9574
Query: 182 DPAAEPAEAGVGTTVAPLPPAPAPSSQPVPAGMTVPP--PPAAAPPLPRALAKPAVFIPV 239
P A+ EA PAP P + VP PP P P+P P V
Sbjct: 9575 PPPAKVPEAPKKIVPEKKVPAPVPKKEKVP-----PPKVPEEPKKPVPEKKVPPKVIKME 9629
Query: 240 NRSPEMQEERLKLPILSEEQVIM 262
P ER + I EE+V++
Sbjct: 9630 EPLPAKVTER-HMQITQEEKVLV 9651
Score = 46.2 bits (108), Expect = 2e-04
Identities = 84/381 (22%), Positives = 144/381 (37%), Gaps = 61/381 (16%)
Query: 14 QQAGPGPSKGPPEPPPVQLELEDKDTLK--GVDASNALVLPGKKK---KKTKAPPLSKKE 68
++ P P E PV + E++ + V ++P KK KK +APP KE
Sbjct: 10808 EEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPP--PKE 10865
Query: 69 KKPLTKKEKKVLQKILEQKEKKSQRAEMLQKLSEVQA---------SEAEMRLFYTTSKL 119
+P EK L+ + ++ +K+ +++A + ++ T K+
Sbjct: 10866 PEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKV 10925
Query: 120 GTGNRMYHTKEKADEVVAPGQEKISSLSGAHRKRRRWPSAEEEEEEEEESESELEEESEL 179
G + K + P +E + L RKR EEEE + E + E ++ +
Sbjct: 10926 PGGEKKVR-KLLPERKPEPKEEVV--LKSVLRKR-----PEEEEPKVEPKKLEKVKKPAV 10977
Query: 180 DEDPAAEPAEAGVGTTVA----------------PLPPAPAPSSQPVPAG--MTVPPPPA 221
E P +P E TV P P PAP +P P T+ PPP
Sbjct: 10978 PEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPV 11037
Query: 222 AAPPLPRALAKPAVFIPV------NRSPEMQEERLKLPILSEEQVIMEAVAEHPIVIVCG 275
P P +A P V +PV ++P+ + + K PI + + + G
Sbjct: 11038 EPEPTP--IAAP-VTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKLRPG 11094
Query: 276 ETGSGKTTQVPQFLYE-----AGFSSEDSIIGVTEPRRVAAVAMSQRVAKEMNLSQRVVS 330
G + P F Y+ F E I +TE V + A+ + + ++
Sbjct: 11095 SGGEKPPDEAP-FTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLVS----PSTAIT 11149
Query: 331 YQIRYEGNVTEETRIKFMTDG 351
++ N+ E + +F+ DG
Sbjct: 11150 TWMKDGSNIRESPKHRFIADG 11170
Score = 44.7 bits (104), Expect = 5e-04
Identities = 58/244 (23%), Positives = 96/244 (39%), Gaps = 27/244 (11%)
Query: 24 PPEPPPVQLELEDKDTLKGVDASNALVLPGKKKKKTKAPPLSKKEKKPLTKKEKKVLQKI 83
P EP P + + LK + +P KK K P + ++ KK +K + + K
Sbjct: 9799 PEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISITK- 9857
Query: 84 LEQKEKKSQRAEMLQKLSEVQASEAEMRLFYTTSKLGTGNRMYHT-KEKADEVVAPGQEK 142
E+++ A++ K V A E ++ ++ R+ KE E VA +E
Sbjct: 9858 REKEQVTEPAAKVPMKPKRVVAEE---KVPVPRKEVAPPVRVPEVPKELEPEEVAFEEEV 9914
Query: 143 ISSLSGAHRKRRRWPSAEEEEEEEEESESELEEESELDEDPAAEPAEAGVGTTVAPLPPA 202
++ + EE EE E + EE E + P + V +P
Sbjct: 9915 VTHV---------------EEYLVEEEEEYIHEEEEFITEEEVVPV---IPVKVPEVPRK 9956
Query: 203 PAPSSQ-PVPAGMTVPPPPAAAPPLPRALAKPAVFIPVNRSPEMQEERLKLPILSEEQVI 261
P P + PVP PPA P +P+ KP +PV + + K+P + ++ V
Sbjct: 9957 PVPEEKKPVPVPKKKEAPPAKVPEVPK---KPEEKVPVLIPKKEKPPPAKVPEVPKKPVP 10013
Query: 262 MEAV 265
E V
Sbjct: 10014 EEKV 10017
Score = 44.3 bits (103), Expect = 7e-04
Identities = 60/279 (21%), Positives = 108/279 (38%), Gaps = 37/279 (13%)
Query: 16 AGPGPSKGPPEPPPVQLELEDKDTLKGVDASNALVLPGKKKKKTKAPP--LSKKEKKPLT 73
A P P + PP V E E+ + + +P ++++ + PP + ++ KK +
Sbjct: 10789 AVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIP 10848
Query: 74 KKEKKVLQKILEQKEKKSQRAEMLQKLS-------------EVQASEAEMRLFYTTSKLG 120
+K+ V++K K+ + ++++K + E +L K
Sbjct: 10849 EKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKV 10908
Query: 121 TGNRMYHTKEKADEVVAPGQEKISSLSGAHRKRRRWPSAEEEEEEEEESESELEEESELD 180
K + + PG EK + R+ P + E +EE +S L + E +
Sbjct: 10909 PEKPQVPEKVELTPLKVPGGEK--------KVRKLLPERKPEPKEEVVLKSVLRKRPE-E 10959
Query: 181 EDPAAEPAE-AGVGTTVAPLPPAPAPSSQPVPAGMTVP----PPPAAAPPLPRALAKPAV 235
E+P EP + V P PP P P + +T P P P + KPA+
Sbjct: 10960 EEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEI-----KPAI 11014
Query: 236 FIPV---NRSPEMQEERLKLPILSEEQVIMEAVAEHPIV 271
+P PE + + +K P + E + A P+V
Sbjct: 11015 PLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVV 11053
Score = 42.0 bits (97), Expect = 0.003
Identities = 59/275 (21%), Positives = 109/275 (39%), Gaps = 38/275 (13%)
Query: 20 PSKGPPEP--PPVQLELEDKDTLKGVDASNALVLPGK---KKKKTKAPPLSK--KEKKPL 72
P K PE PP +++E+ K + + K K +APP ++ +E K
Sbjct: 9612 PKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRA 9671
Query: 73 TKKEKKVLQKILEQKEKKSQRAEMLQKLSE-----VQASEAEMRLFYTTSKLGTGNRMYH 127
+EK + K ++E ++ E +++ + ++A + E + + + R Y
Sbjct: 9672 VPEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPIKEVTIMEEKERAYT 9731
Query: 128 TKEKADEVVAPGQEKISSLSGAHRKRRRWPSAEEEEEEEEESESELEEESELDEDPAAEP 187
+E+A V +E+ K EE ++ EE E E E E+ EP
Sbjct: 9732 LEEEA--VSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEEREYERYEEHEEYITEP 9789
Query: 188 AEAGVGTTVAPLPPAPAPSSQPVPAG-----------MTVPPPPAAAPPLPRALAKPAVF 236
+ V P+P P P+ P + VP P PP P+ +P
Sbjct: 9790 EKP---IPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEP--- 9843
Query: 237 IPVNRSPEMQEERLKLPILS-EEQVIMEAVAEHPI 270
++ EE++++ I E++ + E A+ P+
Sbjct: 9844 ------KKVFEEKIRISITKREKEQVTEPAAKVPM 9872
Score = 41.2 bits (95), Expect = 0.006
Identities = 58/279 (20%), Positives = 96/279 (34%), Gaps = 52/279 (18%)
Query: 20 PSKGPPEPPPVQLELEDKDTLKGVDASNALVLPGKK-----KKKTKAPPLSKKEKKPLTK 74
P+K P PPP E + V+P KK KK + PP E
Sbjct: 10514 PAKKPEAPPPKVPEAPKE------------VVPEKKVPVPPPKKPEVPPTKVPEVPKAAV 10561
Query: 75 KEKKVLQKILEQKEKKSQRAEMLQKLSEVQASEAEMRLFYTTSKLGTGNRMYHTKEKADE 134
EKKV + I + E S E+ + EV EK
Sbjct: 10562 PEKKVPEAIPPKPE--SPPPEVPEAPKEV------------------------VPEKKVP 10595
Query: 135 VVAPGQEKISSLSGAHRKRRRWPSAEEEEEEEEESESELEEESELDEDPAAEPAEAGVGT 194
P + +++ + + P + ++ E +++ E P E V
Sbjct: 10596 AAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPE---VPPTKVPEVPKVAVPEKKVPE 10652
Query: 195 TVAPLPPAPAPSSQPVPAGMTVPPPPAAAPPLPRALAKPAVF------IPVNRSPEMQEE 248
+ P P +P P P + + PPA P A P V +P ++P + +
Sbjct: 10653 AIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAK 10712
Query: 249 RLKLPILSEEQVIMEAVAEHPIVIVCGETGSGKTTQVPQ 287
+ +LP + +V E V E + +V + +VP+
Sbjct: 10713 KPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPE 10751
Score = 40.8 bits (94), Expect = 0.008
Identities = 59/282 (20%), Positives = 107/282 (37%), Gaps = 30/282 (10%)
Query: 20 PSKGPPEPPPVQLELEDKDTLKGVDASNALVLPGKKK---KKTKAPP-----LSKKEKKP 71
P K P P PV L E++ + VLP +++ ++ + P L ++E+ P
Sbjct: 10089 PKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIP 10148
Query: 72 LTKKEKKVLQKILEQKEKKSQRAEMLQKLSE---VQASEAEMRLFYTTSKLGTGNRMYHT 128
++E ++ + ++E+ E+L ++ V A E++ T K+ +
Sbjct: 10149 PEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAP 10208
Query: 129 KEKADEVVAPGQEKISSLSGAHRKRRRWPSAEEEEEEEEESESELEEESELDEDPAAEPA 188
K EV +EK L + E EEE E E E S + + A P
Sbjct: 10209 PAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPR 10268
Query: 189 EAGVGTTVAPLPPAPAP---SSQPVPAGMTVP------------PPPAAAPPLPRALAKP 233
V P P P P + P +P PPA P +P+ + +
Sbjct: 10269 VPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEK 10328
Query: 234 AVFIPVNRSPEMQEERL----KLPILSEEQVIMEAVAEHPIV 271
V +P + + R K+ + ++V+++ E +V
Sbjct: 10329 KVLVPKKEAVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVV 10370
Score = 37.4 bits (85), Expect = 0.083
Identities = 62/283 (21%), Positives = 94/283 (33%), Gaps = 34/283 (12%)
Query: 18 PGPSKGPPEPPPVQLELEDKDTLKGVDASNALVLPGK---------KKKKTKAPPLSKKE 68
P P PPE P E+ + + V P K +KK PP K E
Sbjct: 10572 PKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPE 10631
Query: 69 KKP--------LTKKEKKVLQKILEQKEKKSQRAEMLQKLSEVQASEAEMRLFYTTSKLG 120
P + EKKV + I + E S E+ ++ EV E +
Sbjct: 10632 VPPTKVPEVPKVAVPEKKVPEAIPPKPE--SPPPEVFEEPEEVALEEPPAEVVEEPEPAA 10689
Query: 121 TGNRMYHTK-----EKADEVVAPGQE----KISSLSGAHRKRRRWPSAEEEEEEEEESES 171
K +KA VVA E K+ + ++ P ++ E ++
Sbjct: 10690 PPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKV 10749
Query: 172 ELEEESELDEDPAAEPAEAGVGTTVAP-LPPAPAPSSQPVPAGMTVPPPPAAAPPLPRAL 230
+ + E A P + V P +P P +P VP P A P P
Sbjct: 10750 PEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKP-----AVPVPERAESPPPEVY 10804
Query: 231 AKPAVFIPVNRSPEMQEERLKLPILSEEQVIMEAVAEHPIVIV 273
+P P +E+ + + E +V AV E P I+
Sbjct: 10805 EEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKII 10847
Score = 35.0 bits (79), Expect = 0.41
Identities = 70/347 (20%), Positives = 127/347 (36%), Gaps = 82/347 (23%)
Query: 20 PSKGPPEPPPVQLELEDKDTLKGVDASNALVLPGKKKKKTKAPPLSKKEKKPLT------ 73
P+ +PPP ++E+ K K DA + P K+ T + KK P T
Sbjct: 8970 PTPEEKKPPPKRIEVTKKAVKK--DAKKVVAKP---KEMTPREEIVKKPPPPTTLIPAKA 9024
Query: 74 --------KKEKKVLQKILEQKEKKSQRAEMLQKLSEVQASEAEMRLFYTTSK------- 118
K E+ + I +KE + ++ + +K QA E R+F + +
Sbjct: 9025 PEIIDVSSKAEEVKIMTITRKKEVQKEKEAVYEKK---QAVHKEKRVFIESFEEPYDELE 9081
Query: 119 ----LGTGNRMYHTKEKAD----------EVVAPGQEKISSLSGAHRKRRRWPSAEEEEE 164
+ Y+ + D EV +E + + + EEE E
Sbjct: 9082 VEPYTEPFEQPYYEEPDEDYEEIKVEAKKEVHEEWEEDFEEGQEYYEREEGYDEGEEEWE 9141
Query: 165 EEEESESELEEESELDEDPAAEPAEAGVGTTVAPLPPAPAPSSQPVPAGMTVPPPPAAAP 224
E + ++ + E+ E+ + VPA + P AP
Sbjct: 9142 EAYQEREVIQVQKEVYEE----------------------SHERKVPAKV----PEKKAP 9175
Query: 225 PLPRALAKPAVFIPVNRSPEMQEERL---KLPILSEEQVIME----AVAEHPIVIVCGET 277
P P+ + KP + S M+EE++ K+P +S++ V + V E I +
Sbjct: 9176 PPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQKPSRTPVQEEVIEVKVPAV 9235
Query: 278 GSGKTTQVPQFLYEAGFSSEDSIIGVTEPRRVAA------VAMSQRV 318
+ K + ++ A + E+ + V E ++ VA+S+RV
Sbjct: 9236 HTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVAISKRV 9282
Score = 33.5 bits (75), Expect = 1.2
Identities = 30/124 (24%), Positives = 48/124 (38%), Gaps = 17/124 (13%)
Query: 131 KADEVVAPGQEKISSLSGAHRKRRRWPSAEEEEEEEEESESELEEESELDEDPAAEPAEA 190
K EV +EK+ L K E ++ E + + +++ PA P
Sbjct: 9977 KVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPE-- 10034
Query: 191 GVGTTVAPLPPAPAPSSQ-PVPAGMTVPPPPAAAPPLPRALAKPAVFIPVNRSPEMQEER 249
+P P P + PVPA V PPA P +P+ L IP + P ++
Sbjct: 10035 --------VPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKL------IPEEKKPTPVPKK 10080
Query: 250 LKLP 253
++ P
Sbjct: 10081 VEAP 10084
Score = 32.0 bits (71), Expect = 3.5
Identities = 64/314 (20%), Positives = 104/314 (33%), Gaps = 68/314 (21%)
Query: 25 PEPPPVQLELEDKDTLKGVDASNALVLPGKKKKK-TKAPPLSKK--EKKPLTKKEKKVL- 80
P P P ++E K + V KK+ K P + KK EKK L K++ V
Sbjct: 10281 PTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVPP 10340
Query: 81 ---QKILEQKEKKSQRAEMLQKLS-EVQASEAEMRLFYTTSKLGTGNRMYHTKE--KADE 134
+ +LE+K + R E++ K E++ EAE+ + + E + +E
Sbjct: 10341 AKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEEGEFHEVEE 10400
Query: 135 VVAPGQEKISSLSGAHRKRRRWPSAEEEEEE----------------------------- 165
+ Q ++ + R E EE E
Sbjct: 10401 FIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKIIPPKKPPTKVV 10460
Query: 166 ----------EEESESELEEESELDEDPAAEPAEAG--------VGTTVAPLPPAPAPSS 207
E + +EE+ + E+P P + V P+PPA P +
Sbjct: 10461 PRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEA 10520
Query: 208 QP--VPAG---------MTVPPPPAAAPPLPRALAKPAVFIPVNRSPEMQEERLKLPILS 256
P VP + VPPP P + P +P + PE + + P
Sbjct: 10521 PPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPE 10580
Query: 257 EEQVIMEAVAEHPI 270
+ E V E +
Sbjct: 10581 VPEAPKEVVPEKKV 10594
Score = 31.2 bits (69), Expect = 6.0
Identities = 47/234 (20%), Positives = 83/234 (35%), Gaps = 29/234 (12%)
Query: 54 KKKKKTKAPPLSKKEKKPLTKKEKKVLQKILEQKEKKSQRAEMLQKLSEVQASEAEMRLF 113
K K K P +S+K P KK K++ +KE ++ E+ +K+
Sbjct: 10435 KPKAPPKGPEISEKIIPP-----KKPPTKVVPRKEPPAKVPEVPKKI------------- 10476
Query: 114 YTTSKLGTGNRMYHTKEKADEVVAPGQEKISSLSGAHRKRRRWPSAEEEEEEEEESESEL 173
K+ K EV+ P + K+ P A++ E +
Sbjct: 10477 VVEEKVRVPEEPRVPPTKVPEVLPPKEV-------VPEKKVPVPPAKKPEAPPPKVPEAP 10529
Query: 174 EEESELDEDPAAEPAEAGVGTTVAPLPPAPAPSSQPVPAGMTVPPPPAAAPPLPRALAKP 233
+E + P P + V T P P A + VP +PP P + P P P
Sbjct: 10530 KEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEA--IPPKPES--PPPEVPEAP 10585
Query: 234 AVFIPVNRSPEMQEERLKLPILSEEQVIMEAVAEHPIVIVCGETGSGKTTQVPQ 287
+P + P ++ ++ + + E V E + + + T+VP+
Sbjct: 10586 KEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPE 10639
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 49.3 bits (116), Expect = 2e-05
Identities = 58/260 (22%), Positives = 101/260 (38%), Gaps = 37/260 (14%)
Query: 66 KKEKKPLTKKEKKVLQKILEQKEKKSQRAEMLQKLSEVQASEAEMRLFYTTSKLGTGNRM 125
++E+ + E++ L++ +++E++ +R E ++L + E + RL + R+
Sbjct: 177 ERERLERERLEQEQLERERQERERQ-ERLERQERLERQERLERQERLDRERQERQERERL 235
Query: 126 YHTKEKADEVVAPGQEKISSLSGAHRKRRRWPSAEEEEEEEEESESELEEESELD----- 180
+ + E QE++ + RR SA E S L + S +
Sbjct: 236 ERLERERQE--RERQEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSSASEPGLQA 293
Query: 181 -EDPAAEPAEAGV------GTTVAPLPPAPAPSS----------QPVPAGMTVPPPPAAA 223
PA P++ G+ PLPP PA +S P P T PPPP
Sbjct: 294 ASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPPPP 353
Query: 224 PPLPRALAKPAVFIPVNRSPEMQEERLKLPILSEEQVIMEAVAEHPIVIVCGETGSGKTT 283
PPLP + P P +P + L +SE+ P+ + K
Sbjct: 354 PPLPNQVPPPP---PPPPAPPLPASGFFLASMSED--------NRPLTGLAAAIAGAKLR 402
Query: 284 QVPQFLYEAGFSSEDSIIGV 303
+V + + + F S + IGV
Sbjct: 403 KVSR-MEDTSFPSGGNAIGV 421
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 49.3 bits (116), Expect = 2e-05
Identities = 58/260 (22%), Positives = 101/260 (38%), Gaps = 37/260 (14%)
Query: 66 KKEKKPLTKKEKKVLQKILEQKEKKSQRAEMLQKLSEVQASEAEMRLFYTTSKLGTGNRM 125
++E+ + E++ L++ +++E++ +R E ++L + E + RL + R+
Sbjct: 177 ERERLERERLEQEQLERERQERERQ-ERLERQERLERQERLERQERLDRERQERQERERL 235
Query: 126 YHTKEKADEVVAPGQEKISSLSGAHRKRRRWPSAEEEEEEEEESESELEEESELD----- 180
+ + E QE++ + RR SA E S L + S +
Sbjct: 236 ERLERERQE--RERQEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSSASEPGLQA 293
Query: 181 -EDPAAEPAEAGV------GTTVAPLPPAPAPSS----------QPVPAGMTVPPPPAAA 223
PA P++ G+ PLPP PA +S P P T PPPP
Sbjct: 294 ASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPPPP 353
Query: 224 PPLPRALAKPAVFIPVNRSPEMQEERLKLPILSEEQVIMEAVAEHPIVIVCGETGSGKTT 283
PPLP + P P +P + L +SE+ P+ + K
Sbjct: 354 PPLPNQVPPPP---PPPPAPPLPASGFFLASMSED--------NRPLTGLAAAIAGAKLR 402
Query: 284 QVPQFLYEAGFSSEDSIIGV 303
+V + + + F S + IGV
Sbjct: 403 KVSR-MEDTSFPSGGNAIGV 421
>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo
sapiens]
Length = 2462
Score = 48.5 bits (114), Expect = 4e-05
Identities = 49/222 (22%), Positives = 79/222 (35%), Gaps = 50/222 (22%)
Query: 126 YHTKEKADEVVAPGQEKISSLSGAHRKRRRWPSAEEEE--------------------EE 165
Y ++ DE++ + K+ A RK+++ P+A EE EE
Sbjct: 656 YKKRQNLDEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEE 715
Query: 166 E--EESESELEEESELDEDPAAEPAEAGVGTTVAPLPPAPAPSSQPVPAGMTVPPPPAAA 223
E EE+E+ + S+ + P+ A P PPA + P P T PP A
Sbjct: 716 EMVEEAEATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPA 775
Query: 224 ----------------PPLPRALAKPAVFIPVNR-------SPEMQEERLKLPILSEEQV 260
PP P + + P +P +P ++E + P +EE
Sbjct: 776 PTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELA 835
Query: 261 IMEAVAEHPIVIVCGE-----TGSGKTTQVPQFLYEAGFSSE 297
+ AE P+ C E GK + + E +E
Sbjct: 836 VDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAE 877
Score = 42.4 bits (98), Expect = 0.003
Identities = 59/243 (24%), Positives = 88/243 (36%), Gaps = 28/243 (11%)
Query: 19 GPSKGPPEPPPVQLELEDKDTLKGVDASNALVLPGKKKKKTKAPPLSKKEKKPLTKKEKK 78
GP GPP PPP + + T +A+ A P + PP+ KE+K ++E
Sbjct: 760 GPPPGPPTPPPEDIPAPTEPT-PASEATGAPTPPPAPPSPSAPPPVVPKEEK---EEETA 815
Query: 79 VLQKILEQKEKKSQRAEMLQKLSEVQASEAEMRLFYTTSKLGTGNRMYHTKEKADEVVAP 138
+ E +E+K AE L V +AE + ++ +A E A
Sbjct: 816 AAPPVEEGEEQKPPAAEEL----AVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAE 871
Query: 139 GQEKISSLSGAHRKRRRWPSAEEEEEEEEE---SESELEEESELDEDPAAEPAEAGVGTT 195
G K G + S+ ++ + S E++E D++ P + + T
Sbjct: 872 GALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPT 931
Query: 196 VAP----LPPAPAPSSQPVPAGMTVPP--------PPA--AAPPLPRALAKPAVFIPVNR 241
P P P Q +PP PP AAP P A PA P N
Sbjct: 932 GDPRANASPQKPLDLKQLKQRAAAIPPIQVTKVHEPPREDAAPTKP---APPAPPPPQNL 988
Query: 242 SPE 244
PE
Sbjct: 989 QPE 991
Score = 31.6 bits (70), Expect = 4.6
Identities = 28/120 (23%), Positives = 55/120 (45%), Gaps = 19/120 (15%)
Query: 75 KEKKVLQKILEQKEKKSQRAEMLQKLSEV--------QASEAEMRLFYTTSKLGTG---- 122
K+++V+ EQ EK++ R + +Q + + AE L+Y +K
Sbjct: 424 KDRQVMNMWSEQ-EKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSL 482
Query: 123 -NRMYHTKEKADEVVAPGQEKISSLSGAHRKRRRWPSAEEEEEEEEESESELEEESELDE 181
R Y + K+ + Q++ ++++ P + +EE++E+E E E E+E E E
Sbjct: 483 VRRSYRRRGKSQQ-----QQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEEEKPE 537
Score = 31.2 bits (69), Expect = 6.0
Identities = 40/167 (23%), Positives = 62/167 (37%), Gaps = 30/167 (17%)
Query: 11 KGRQQAGPGPSKGPPEPPPVQLELE------DKDTL----KGVDASNALVLPGKKKKKTK 60
K R G PP PP ELE K+ L VD +V K K K
Sbjct: 137 KDRSLTGKLEPVSPPSPPHTDPELELVPPRLSKEELIQNMDRVDREITMVEQQISKLKKK 196
Query: 61 APPLSKKEKK-----------PLTKKEKKVLQKILEQKEKKSQRAEMLQKLSEVQASEAE 109
L ++ K P+ K + ++Q I ++ KK AE ++ E + E
Sbjct: 197 QQQLEEEAAKPPEPEKPVSPPPIESKHRSLVQIIYDENRKK---AEAAHRILEGLGPQVE 253
Query: 110 MRLFYTTSKLGTGNRMYHTKEKADEVVAPGQEKISSLSGAHRKRRRW 156
+ L+ S R YH K ++ A ++ I + R++W
Sbjct: 254 LPLYNQPS----DTRQYHENIKINQ--AMRKKLILYFKRRNHARKQW 294
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.133 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 50,038,856
Number of Sequences: 37866
Number of extensions: 2678102
Number of successful extensions: 48984
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 509
Number of HSP's successfully gapped in prelim test: 1034
Number of HSP's that attempted gapping in prelim test: 27385
Number of HSP's gapped (non-prelim): 13684
length of query: 1157
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1044
effective length of database: 13,968,660
effective search space: 14583281040
effective search space used: 14583281040
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.