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Search of human proteins with 27262651
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27262651 ataxin 2 related protein isoform D [Homo sapiens]
(1044 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27262651 ataxin 2 related protein isoform D [Homo sapiens] 2148 0.0
gi|27262653 ataxin 2 related protein isoform E [Homo sapiens] 2114 0.0
gi|27262645 ataxin 2 related protein isoform B [Homo sapiens] 2112 0.0
gi|27262649 ataxin 2 related protein isoform C [Homo sapiens] 2112 0.0
gi|27262647 ataxin 2 related protein isoform A [Homo sapiens] 2112 0.0
gi|171543895 ataxin 2 [Homo sapiens] 622 e-178
gi|163965366 nascent polypeptide-associated complex alpha subuni... 105 2e-22
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 99 3e-20
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 97 1e-19
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 92 3e-18
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 87 1e-16
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 85 4e-16
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 85 4e-16
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 83 1e-15
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 79 2e-14
gi|55750053 atrophin-1 [Homo sapiens] 78 5e-14
gi|55750041 atrophin-1 [Homo sapiens] 78 5e-14
gi|150170670 piccolo isoform 2 [Homo sapiens] 76 2e-13
gi|150378539 piccolo isoform 1 [Homo sapiens] 76 2e-13
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 75 3e-13
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 72 3e-12
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 71 6e-12
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 71 6e-12
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 71 6e-12
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 71 6e-12
gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s... 70 8e-12
gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s... 70 8e-12
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens] 69 2e-11
gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens] 69 3e-11
gi|151301154 mucin 6, gastric [Homo sapiens] 68 4e-11
>gi|27262651 ataxin 2 related protein isoform D [Homo sapiens]
Length = 1044
Score = 2148 bits (5565), Expect = 0.0
Identities = 1044/1044 (100%), Positives = 1044/1044 (100%)
Query: 1 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG
Sbjct: 1 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
Query: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120
PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN
Sbjct: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120
Query: 121 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180
SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV
Sbjct: 121 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180
Query: 181 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240
DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD
Sbjct: 181 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240
Query: 241 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300
YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA
Sbjct: 241 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300
Query: 301 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360
REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP
Sbjct: 301 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360
Query: 361 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420
RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK
Sbjct: 361 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420
Query: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480
TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV
Sbjct: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480
Query: 481 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540
TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF
Sbjct: 481 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540
Query: 541 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600
QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT
Sbjct: 541 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600
Query: 601 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660
ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN
Sbjct: 601 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660
Query: 661 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720
PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG
Sbjct: 661 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720
Query: 721 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780
PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA
Sbjct: 721 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780
Query: 781 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840
ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP
Sbjct: 781 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840
Query: 841 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900
QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ
Sbjct: 841 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900
Query: 901 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960
APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM
Sbjct: 901 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960
Query: 961 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020
AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP
Sbjct: 961 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020
Query: 1021 YPYIGHPQVQSHPSQQLPFHPPGN 1044
YPYIGHPQVQSHPSQQLPFHPPGN
Sbjct: 1021 YPYIGHPQVQSHPSQQLPFHPPGN 1044
>gi|27262653 ataxin 2 related protein isoform E [Homo sapiens]
Length = 1044
Score = 2114 bits (5478), Expect = 0.0
Identities = 1032/1043 (98%), Positives = 1032/1043 (98%), Gaps = 8/1043 (0%)
Query: 1 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG
Sbjct: 1 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
Query: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120
PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN
Sbjct: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120
Query: 121 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180
SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV
Sbjct: 121 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180
Query: 181 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240
DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD
Sbjct: 181 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240
Query: 241 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300
YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA
Sbjct: 241 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300
Query: 301 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360
REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP
Sbjct: 301 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360
Query: 361 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420
RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK
Sbjct: 361 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420
Query: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480
TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV
Sbjct: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480
Query: 481 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540
TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF
Sbjct: 481 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540
Query: 541 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600
QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT
Sbjct: 541 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600
Query: 601 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660
ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN
Sbjct: 601 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660
Query: 661 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720
PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG
Sbjct: 661 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720
Query: 721 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780
PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA
Sbjct: 721 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780
Query: 781 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840
ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP
Sbjct: 781 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840
Query: 841 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900
QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ
Sbjct: 841 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900
Query: 901 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960
APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM
Sbjct: 901 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960
Query: 961 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020
AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP
Sbjct: 961 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020
Query: 1021 YPYIGHPQVQSHPSQQLPFHPPG 1043
YPYIGHPQ P PPG
Sbjct: 1021 YPYIGHPQA--------PLPPPG 1035
>gi|27262645 ataxin 2 related protein isoform B [Homo sapiens]
Length = 1062
Score = 2112 bits (5473), Expect = 0.0
Identities = 1032/1043 (98%), Positives = 1032/1043 (98%), Gaps = 2/1043 (0%)
Query: 1 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG
Sbjct: 1 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
Query: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120
PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN
Sbjct: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120
Query: 121 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180
SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV
Sbjct: 121 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180
Query: 181 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240
DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD
Sbjct: 181 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240
Query: 241 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300
YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA
Sbjct: 241 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300
Query: 301 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360
REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP
Sbjct: 301 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360
Query: 361 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420
RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK
Sbjct: 361 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420
Query: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480
TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV
Sbjct: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480
Query: 481 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540
TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF
Sbjct: 481 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540
Query: 541 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600
QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT
Sbjct: 541 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600
Query: 601 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660
ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN
Sbjct: 601 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660
Query: 661 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720
PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG
Sbjct: 661 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720
Query: 721 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780
PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA
Sbjct: 721 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780
Query: 781 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840
ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP
Sbjct: 781 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840
Query: 841 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900
QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ
Sbjct: 841 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900
Query: 901 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960
APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM
Sbjct: 901 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960
Query: 961 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020
AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP
Sbjct: 961 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020
Query: 1021 YPYIGHPQVQSHPSQQLPFHPPG 1043
YPYIGHP Q Q P P G
Sbjct: 1021 YPYIGHP--QGEQPGQAPGFPGG 1041
Score = 38.1 bits (87), Expect = 0.044
Identities = 24/76 (31%), Positives = 29/76 (38%), Gaps = 2/76 (2%)
Query: 10 PSQPQQPPPTQQAVARRPPGGTSPPNGGLP--GPLATSAAPPGPPAAASPCLGPVAAAGS 67
P P P P Q + P PP G +P G A SA+ P P G
Sbjct: 977 PPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQPGQAP 1036
Query: 68 GLRRGAEGILAPQPPP 83
G GA+ + P PPP
Sbjct: 1037 GFPGGADDRIPPLPPP 1052
>gi|27262649 ataxin 2 related protein isoform C [Homo sapiens]
Length = 1097
Score = 2112 bits (5473), Expect = 0.0
Identities = 1032/1043 (98%), Positives = 1032/1043 (98%), Gaps = 2/1043 (0%)
Query: 1 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG
Sbjct: 1 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
Query: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120
PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN
Sbjct: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120
Query: 121 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180
SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV
Sbjct: 121 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180
Query: 181 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240
DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD
Sbjct: 181 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240
Query: 241 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300
YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA
Sbjct: 241 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300
Query: 301 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360
REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP
Sbjct: 301 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360
Query: 361 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420
RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK
Sbjct: 361 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420
Query: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480
TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV
Sbjct: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480
Query: 481 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540
TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF
Sbjct: 481 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540
Query: 541 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600
QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT
Sbjct: 541 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600
Query: 601 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660
ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN
Sbjct: 601 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660
Query: 661 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720
PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG
Sbjct: 661 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720
Query: 721 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780
PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA
Sbjct: 721 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780
Query: 781 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840
ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP
Sbjct: 781 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840
Query: 841 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900
QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ
Sbjct: 841 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900
Query: 901 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960
APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM
Sbjct: 901 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960
Query: 961 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020
AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP
Sbjct: 961 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020
Query: 1021 YPYIGHPQVQSHPSQQLPFHPPG 1043
YPYIGHP Q Q P P G
Sbjct: 1021 YPYIGHP--QGEQPGQAPGFPGG 1041
>gi|27262647 ataxin 2 related protein isoform A [Homo sapiens]
Length = 1075
Score = 2112 bits (5473), Expect = 0.0
Identities = 1032/1043 (98%), Positives = 1032/1043 (98%), Gaps = 2/1043 (0%)
Query: 1 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG
Sbjct: 1 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
Query: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120
PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN
Sbjct: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120
Query: 121 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180
SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV
Sbjct: 121 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180
Query: 181 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240
DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD
Sbjct: 181 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240
Query: 241 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300
YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA
Sbjct: 241 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300
Query: 301 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360
REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP
Sbjct: 301 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360
Query: 361 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420
RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK
Sbjct: 361 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420
Query: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480
TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV
Sbjct: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480
Query: 481 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540
TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF
Sbjct: 481 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540
Query: 541 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600
QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT
Sbjct: 541 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600
Query: 601 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660
ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN
Sbjct: 601 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660
Query: 661 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720
PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG
Sbjct: 661 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720
Query: 721 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780
PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA
Sbjct: 721 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780
Query: 781 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840
ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP
Sbjct: 781 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840
Query: 841 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900
QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ
Sbjct: 841 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900
Query: 901 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960
APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM
Sbjct: 901 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960
Query: 961 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020
AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP
Sbjct: 961 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020
Query: 1021 YPYIGHPQVQSHPSQQLPFHPPG 1043
YPYIGHP Q Q P P G
Sbjct: 1021 YPYIGHP--QGEQPGQAPGFPGG 1041
>gi|171543895 ataxin 2 [Homo sapiens]
Length = 1313
Score = 622 bits (1604), Expect = e-178
Identities = 461/1206 (38%), Positives = 620/1206 (51%), Gaps = 225/1206 (18%)
Query: 2 LKPQPLQQPSQPQQPPPTQQAVARR--PPGGTSPPNGGLPGPLATSAAPPGPPAAASPCL 59
LKPQ QQ Q QQ QQ ++ PP + G G LA+ AA P P ++S
Sbjct: 163 LKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSP--SSSSVS 220
Query: 60 GPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPV-FEGVY 118
A A S + G P G RG+++ KG PQS + F+G+Y
Sbjct: 221 SSSATAPSSVVAATSGGGRP-----------------GLGRGRNSNKGLPQSTISFDGIY 263
Query: 119 NNSRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRRED 178
N RM+H LT+VVGS C+V+VKNG YEG+FKT S K +L +DA H K++E + GP+RE+
Sbjct: 264 ANMRMVHILTSVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHEKSTESSSGPKREE 323
Query: 179 IVDTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGD--S 236
I+++++FK SD ++V F+++D +YA +D FTDSAI+ +KVNGEHKEK L+ W+ G+ +
Sbjct: 324 IMESILFKCSDFVVVQFKDMDSSYAKRDAFTDSAIS--AKVNGEHKEKDLEPWDAGELTA 381
Query: 237 NSDDYDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRA 296
N + LE+D+SNGWDPN+MF++NEENYGV +TYDSSLSSYTVPLE+DNSEEF +RE RA
Sbjct: 382 NEELEALENDVSNGWDPNDMFRYNEENYGVVSTYDSSLSSYTVPLERDNSEEFLKREARA 441
Query: 297 AQLAREIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRV 356
QLA EIESS QY+ R+A+ENDD R+EEEK++AVQR S RE S+ +RE KYIP QR
Sbjct: 442 NQLAEEIESSAQYKARVALENDD-RSEEEKYTAVQRNSSEREGHSINTRENKYIPPGQRN 500
Query: 357 REG-PRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGG---PSRM-SPK 411
RE G R +S R G+PG S+P R H + +P GS+ R +NGG PS SP
Sbjct: 501 REVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCPSPS 560
Query: 412 AQRPLR----------GAKTLSSPSNRPSGETSVPP---------------PPAVGRMYP 446
++ P R A T + P +RP S PP P + P
Sbjct: 561 SRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGP 620
Query: 447 PR-SPK----------SAAPAPISASCP----EPPIGSAVPTSSASIPVTSSVSD--PGV 489
PR SPK SA IS+ PP +A P + + P + S GV
Sbjct: 621 PRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSSVVSGV 680
Query: 490 GSISP----------------------ASPKISLAPTDVKELSTKEPGRTLEPQELARIA 527
+SP ASP+ + PT+ ++ P + P A
Sbjct: 681 PRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEA--VAMPIPAASPTPASPASNR 738
Query: 528 GKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPEN-SLDPFPPRILKEEPKG-------K 579
P + + R Q Q + P+ + EN + P K E KG
Sbjct: 739 AVTPSSEAKDSRLQ--------DQRQNSPAGNKENIKPNETSPSFSKAENKGISPVVSEH 790
Query: 580 EKEVDGL------------LTSEPMGSPVSSKTE-------------------------- 601
K++D L TSE M ++ E
Sbjct: 791 RKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSS 850
Query: 602 ---SVSDKEDKPPLAPSGGTEGPEQPPPPCPS---QTGSPPVGLIKGEDKDEGPVAEQVK 655
S S K + P ++PS + + P S QT SP K + +++ AEQV+
Sbjct: 851 NCTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVR 910
Query: 656 KSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSI-----PVLTAGQSGLYSPQY 710
KSTLNPNAKEFNP S K ++TPTSP P+ +PS+ P Q ++P
Sbjct: 911 KSTLNPNAKEFNPRS--FSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNM 968
Query: 711 ISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQA 770
+ +P + P VQ +YP P++ +P Q K A ++P QR DQH ++ MM
Sbjct: 969 MYPVP---VSPGVQ--PLYPIPMT-PMPVNQAKTYRAVPNMPQQRQDQHHQSA---MMHP 1019
Query: 771 AAAAGPPLVAATP-YSS-YIPYNPQQFPGQPAMMQPMAHYPSQ--PVFAPMLQSNPRMLT 826
A+AAGPP+ A P YS+ Y+ Y+PQQFP QP ++Q + HY SQ V++P++Q N RM+
Sbjct: 1020 ASAAGPPIAATPPAYSTQYVAYSPQQFPNQP-LVQHVPHYQSQHPHVYSPVIQGNARMMA 1078
Query: 827 SGSHPQ-AIVSSSTPQYPSAEQPTPQALYA---------------------TVHQSYPHH 864
+H Q +VSSS QY + EQ A+YA ++ Q Y H
Sbjct: 1079 PPTHAQPGLVSSSATQYGAHEQ--THAMYACPKLPYNKETSPSFYFAISTGSLAQQYAHP 1136
Query: 865 ATQLHAH--QPQPATTPTGSQPQSQHA----APSPV---QHQAGQAPHLGSGQPQQNLYH 915
LH H PQP+ TPTG Q QSQH APSPV QHQA QA HL S Q Q +YH
Sbjct: 1137 NATLHPHTPHPQPSATPTGQQ-QSQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAIYH 1195
Query: 916 PGALTGTPPSLPPGPSAQSPQSSFP-QPAAVYAIHHQQLPHGFTN---MAHVTQAHVQTG 971
G L TPPS+ P + QSPQ+SFP V+ IH + +TN MAHV QAHVQ+G
Sbjct: 1196 AG-LAPTPPSMTPASNTQSPQNSFPAAQQTVFTIHPSHVQPAYTNPPHMAHVPQAHVQSG 1254
Query: 972 ITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQVQS 1031
+ P HP A P +M PP G PQ A+ QS + + ST + +PY+ HP VQ+
Sbjct: 1255 MV---PSHPTAHAPMMLMTTQPP----GGPQAALAQSALQPIPVSTTAHFPYMTHPSVQA 1307
Query: 1032 HPSQQL 1037
H QQL
Sbjct: 1308 HHQQQL 1313
Score = 39.3 bits (90), Expect = 0.020
Identities = 37/134 (27%), Positives = 52/134 (38%), Gaps = 10/134 (7%)
Query: 362 GGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKT 421
G + +R G + PPR L +PG A GP MS K Q+ + +
Sbjct: 115 GAPPAAPTRASPLGARASPPRSGVSLARPAPGCPRPACEPVYGPLTMSLKPQQQQQQQQQ 174
Query: 422 LSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIP-- 479
+ + PPP A P S A+PA + P S+V +SSA+ P
Sbjct: 175 QQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPS-----PSSSSVSSSSATAPSS 229
Query: 480 ---VTSSVSDPGVG 490
TS PG+G
Sbjct: 230 VVAATSGGGRPGLG 243
Score = 35.4 bits (80), Expect = 0.28
Identities = 45/155 (29%), Positives = 57/155 (36%), Gaps = 14/155 (9%)
Query: 343 ASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPR-GPHHLDNSSPGPGSEARGI 401
A+R + L + R RGG ++ G P + PP GP SSP S+ G
Sbjct: 22 AARWPGWRSLQRPARRSGRGGG--GAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGS 79
Query: 402 NGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVP--PPPAVGRMYPPRSPKSAAPAPIS 459
NG R L G L P RP +P P A PP +P A+P
Sbjct: 80 NGNGGGAFRPGSRRLLG---LGGPP-RPFVVLLLPLASPGA-----PPAAPTRASPLGAR 130
Query: 460 ASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISP 494
AS P + A P P V P S+ P
Sbjct: 131 ASPPRSGVSLARPAPGCPRPACEPVYGPLTMSLKP 165
Score = 33.9 bits (76), Expect = 0.82
Identities = 34/110 (30%), Positives = 40/110 (36%), Gaps = 20/110 (18%)
Query: 21 QAVARRPPGGTSPPNGGLPGPLATSA-APPGP---------PAAASPCLGPVAAAGSGLR 70
Q ARR G G PGP ++A PPGP P +AS C G G R
Sbjct: 32 QRPARRSGRGGG---GAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFR 88
Query: 71 RGAEGILAPQPPPPQ-----QHQERPGAAAIGSARGQSTG--KGPPQSPV 113
G+ +L PP PGA R G PP+S V
Sbjct: 89 PGSRRLLGLGGPPRPFVVLLLPLASPGAPPAAPTRASPLGARASPPRSGV 138
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 105 bits (262), Expect = 2e-22
Identities = 178/750 (23%), Positives = 251/750 (33%), Gaps = 115/750 (15%)
Query: 345 REGKYIPLPQRVREGPRGGVRCSSSRGGR--PGLSSLPPRGPHHLDNSSPGPGSEARGIN 402
+EG P P ++ P + SS + R P +P P +P P +
Sbjct: 897 KEGPATPAP---KQAPALSMTSSSPKKARATPAPKGIPA-SPSPKGAPTP-PAATPPSPK 951
Query: 403 GGPSRMSPK-------AQRPL-RGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAA 454
GGP+ SPK A P +G SP P+ + PP P G P SPK A
Sbjct: 952 GGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATP--SPK-GA 1008
Query: 455 PAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEP 514
P P + + P P S A+ P S P + +P SPK S A T + + + P
Sbjct: 1009 PTPPAVTPPSP------KGSPAATPFPKGASTP--PAATPPSPKGSPAATPLPKGAPTTP 1060
Query: 515 GRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLD---PFPPRI 571
TL + + G A P P P PP
Sbjct: 1061 AATLPSPKGGPATPSLKGAPTPP------------AATPPSPKGGPATPSPKGAPMPPAA 1108
Query: 572 LKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQ 631
PKG GL T G+P + S K P G P PP
Sbjct: 1109 TPPSPKG------GLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGG 1162
Query: 632 TGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHS 691
+PP KG K P+ K PT P + +P P+
Sbjct: 1163 LATPPP---KGAPTTPAATPPSPKGGLATPSPKG-APTTPAATPPSPKGGLATPSPKGAP 1218
Query: 692 TPSIPVLTAGQSGLYSPQ-------YISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKY 744
T + + GL +P + P GPA P+ P P + + P +G
Sbjct: 1219 TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGL 1278
Query: 745 RGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQP 804
+ PP + + PP + A PP A TP ++ P +P+ PG P P
Sbjct: 1279 -----ATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAA-TPPSPKGSPGTP----P 1328
Query: 805 MAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHH 864
P+ P P L + + P + +TP S E PTP A + P H
Sbjct: 1329 PKGAPTPPAVTPPSPKGTPTLPA-TTPSSKGGPTTPS--SKEGPTPPA-------ATPSH 1378
Query: 865 ATQLHAHQPQPATTPTGSQPQSQHAAP-----SPVQHQAGQAPHLGSGQPQQNLYHPGAL 919
P P P P+ +P SP + A G+ P + P A+
Sbjct: 1379 KGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAV 1438
Query: 920 TGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPH 979
TP SL P+ +P+ PA + LP A Q +++P
Sbjct: 1439 --TPVSLKKAPATSAPKGG---PATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKA 1493
Query: 980 P------GAPHPPQVMLLHP------PQSHGGP------------PQGAVPQSGV--PAL 1013
P GAP P V+ P P S P P P+ + PA+
Sbjct: 1494 PATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAM 1553
Query: 1014 SASTPSPYPYIGHP-QVQSHPSQQLPFHPP 1042
+ +P P I P + + PS + PP
Sbjct: 1554 TVPSPKKTPAIPTPKEAPATPSSKEASSPP 1583
Score = 95.9 bits (237), Expect = 2e-19
Identities = 187/770 (24%), Positives = 257/770 (33%), Gaps = 119/770 (15%)
Query: 335 SGRESPSLASREGKYIPLPQRVREGPRGGVRCSSSRGGR--PGLSSLPPRG-----PHHL 387
S + P+ S +G P P P+GG S +G P ++ P+G P
Sbjct: 972 SPKGGPATPSPKGAPTP-PAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPK 1030
Query: 388 DNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGET--SVPPPPAVGRMY 445
S+P P + G P+ P A TL SP P+ + P PPA
Sbjct: 1031 GASTP-PAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAA---- 1085
Query: 446 PPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTD 505
P SPK P P PP + P+ + P + +P SPK LA
Sbjct: 1086 TPPSPKGGPATPSPKGAPMPPAATP-PSPKGGLATPPHKGAPTTPAATPPSPKGGLATPP 1144
Query: 506 VKELSTKEPGRTLEPQE-LA----RIAGKVPGLQNEQKRFQLEELRKFGAQFK---LQPS 557
K T P+ LA + A P + L GA PS
Sbjct: 1145 PKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPS 1204
Query: 558 -----SSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPL 612
++P P P PKG GL T P G+P + S K
Sbjct: 1205 PKGGLATPSPKGAPTTPAATPPSPKG------GLATPSPKGAPTTPAATPPSPKGGPATP 1258
Query: 613 APSGGTEGPEQPPPPC------PSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEF 666
P G P PP P G+P ++ GP K + P A
Sbjct: 1259 PPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPP 1318
Query: 667 NP-------------TKPLLSVNKSTSTPTSP--------GPRTHST---PSIPVLTAGQ 702
+P T P ++ TPT P GP T S+ P+ P T
Sbjct: 1319 SPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSH 1378
Query: 703 SGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGA-----KGSLPPQRSD 757
G P P+ GPA+ +P+ P S +V K A +G+ P + D
Sbjct: 1379 KG--GPAMTPPSPK--RGPAIPSPK--GDPTSPAVIPLSPKKAPATPVTREGAATPSKGD 1432
Query: 758 QHQPASAPPMMQAAAAAGPPLVA-ATPYSSYIPYNPQQFPGQPAMMQPMAHYP----SQP 812
PA P ++ A A P ATP S P P P P+ +P A S P
Sbjct: 1433 LTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTP--PSPKEPPAPKQVATSSSP 1490
Query: 813 VFAPMLQSNPRMLTSGSHPQAIVSS--STPQYPSAEQPTPQALYATVHQSYPHHATQLHA 870
AP + P + + + P I SS P PS+ + + + P A
Sbjct: 1491 KKAP---ATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEA 1547
Query: 871 HQPQPATTP----TGSQPQSQHAAPSPVQHQAGQAP------HLGSGQPQQNLYHPGALT 920
P T P T + P + A +P +A P + G+ P++ L P A+T
Sbjct: 1548 LIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPP-AVT 1606
Query: 921 GTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHP 980
P P P A +P S PA P G VT + ++ T+
Sbjct: 1607 SPSPKEAPTPPAVTPPSPEKGPAT-------PAPKGTPTSPPVTPSSLKDSPTS------ 1653
Query: 981 GAPHPPQV---MLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHP 1027
P V M PQ+ G P P + L A P P I P
Sbjct: 1654 ----PASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAP 1699
Score = 94.7 bits (234), Expect = 4e-19
Identities = 159/695 (22%), Positives = 214/695 (30%), Gaps = 136/695 (19%)
Query: 375 GLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMS----PKAQRPLRGAK----TLSSPS 426
G+S P S GP + ++ S + P+ +G+K T SP+
Sbjct: 798 GVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPT 857
Query: 427 NRPSGETSVPPPPAVGRMYPP--RSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSV 484
P P P AV + P P P P + P P G A P + ++ +
Sbjct: 858 --PPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTS 915
Query: 485 SDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEE 544
S P +PA I +P+ K T P+
Sbjct: 916 SSPKKARATPAPKGIPASPSP-KGAPTPPAATPPSPK----------------------- 951
Query: 545 LRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVS 604
++P P PP PKG G T P G+P S
Sbjct: 952 ----------GGPATPSPKWAPTPPAATPPSPKG------GPATPSPKGAPTPPAATPPS 995
Query: 605 DKEDKPPLAPSGGTEGPEQPPPPCPSQTGSP-PVGLIKGEDKDEGPVAEQVKKSTLNPNA 663
K +P G P P PS GSP KG K S
Sbjct: 996 PKGGPATPSPKGAPTPPAVTP---PSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPL 1052
Query: 664 KEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAV 723
+ PT P ++ P +P + TP P T P GPA
Sbjct: 1053 PKGAPTTPAATLPSPKGGPATPSLKGAPTP--PAATP--------------PSPKGGPAT 1096
Query: 724 QAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAAT- 782
+P+ P P + + P +G + PP + PA+ PP + A PP A T
Sbjct: 1097 PSPKGAPMPPAATPPSPKGGL-----ATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTT 1151
Query: 783 -------PYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPR--MLTSGSHPQA 833
P P+ P PA P P + P + P T S
Sbjct: 1152 PAATPPSPKGGLATPPPKGAPTTPAATPPS---PKGGLATPSPKGAPTTPAATPPSPKGG 1208
Query: 834 IVSSS---TPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQ-----PATTPTGSQPQ 885
+ + S P P+A P+P+ AT P A A P PAT P P
Sbjct: 1209 LATPSPKGAPTTPAATPPSPKGGLAT---PSPKGAPTTPAATPPSPKGGPATPPPKGAPT 1265
Query: 886 SQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAV 945
A P ++ PH G+ P TPPS GP+ P+ + PAA
Sbjct: 1266 PPAATPPSLKGGLATPPHKGA---------PNPAVVTPPSPKGGPATSPPKGAPTPPAAT 1316
Query: 946 YAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGP--PQG 1003
P G + PP GAP PP V PP G P P
Sbjct: 1317 -----PPSPKG----------------SPGTPPPKGAPTPPAVT---PPSPKGTPTLPAT 1352
Query: 1004 AVPQSGVPALSASTPSPYPYIGHPQVQSHPSQQLP 1038
G P +S P P P + P+ P
Sbjct: 1353 TPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPP 1387
Score = 94.0 bits (232), Expect = 7e-19
Identities = 169/686 (24%), Positives = 246/686 (35%), Gaps = 113/686 (16%)
Query: 406 SRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPK------SAAPAPIS 459
S P A P L++ P SVP P PP + K ++A AP++
Sbjct: 705 SENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVA 764
Query: 460 AS---CPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGR 516
+S CP G++ T+S+ +T P +S SP+ PT P
Sbjct: 765 SSPKECPTEDSGASA-TASSKGTLTYLADSPSPLGVS-VSPQTKRPPTKKGSAGPDTPIG 822
Query: 517 TLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEP 576
L A +P + + + A SP+ + P P + P
Sbjct: 823 NLSSPVSPVEASFLP-----ENSLSFQGSKDSPATTHSPTPPSPKGA--PTPSAVTPLSP 875
Query: 577 KG---KEKEV------------DGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGP 621
KG KE +G T P +P S T S S K+ + AP G
Sbjct: 876 KGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSS-SPKKARATPAPKG----- 929
Query: 622 EQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTST 681
P P P +PP P + + +T +P ++ PT P +
Sbjct: 930 -IPASPSPKGAPTPPAAT---------PPSPKGGPATPSP---KWAPTPPAATPPSPKGG 976
Query: 682 PTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQ 741
P +P P+ TP P T P GPA +P+ P P + + P
Sbjct: 977 PATPSPKGAPTP--PAATP--------------PSPKGGPATPSPKGAPTPPAVTPPSP- 1019
Query: 742 GKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGP-PLVAATPYSSYIPYNPQQFPGQPA 800
+G+ + P + PA+ PP + + AA P P A T ++ +P +P+ P P+
Sbjct: 1020 ---KGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLP-SPKGGPATPS 1075
Query: 801 MM---QPMAHYPSQPVFAPMLQS--NPRMLTSGSHPQAIVSSSTPQY------PSAEQPT 849
+ P A P P P S M + + P +TP + P+A P+
Sbjct: 1076 LKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPS 1135
Query: 850 PQALYA---------TVHQSYPHHATQLHAHQPQPA-TTPTGSQPQSQHAAPSPVQHQAG 899
P+ A T + P L P+ A TTP + P + +P A
Sbjct: 1136 PKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAP 1195
Query: 900 QAPHLGSGQPQQNLYHP---GALT---GTPPSLPPGPSAQSPQSSFPQPAAVYAIHH--- 950
P P+ L P GA T TPPS G + SP+ + PAA
Sbjct: 1196 TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGP 1255
Query: 951 -QQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSG 1009
P G T ++ G+ A PPH GAP+P V PP GGP P G
Sbjct: 1256 ATPPPKGAPTPPAATPPSLKGGL--ATPPHKGAPNPAVVT---PPSPKGGP--ATSPPKG 1308
Query: 1010 VPALSAST-PSPYPYIGHPQVQSHPS 1034
P A+T PSP G P + P+
Sbjct: 1309 APTPPAATPPSPKGSPGTPPPKGAPT 1334
Score = 81.3 bits (199), Expect = 4e-15
Identities = 166/716 (23%), Positives = 240/716 (33%), Gaps = 140/716 (19%)
Query: 417 RGAKTLSSPSNRPSGETSVPPPPAVG---RMYPPRSPKSAAPAPISASCPEPPIGS---- 469
+G T+SS + PSG +V ++ + SP + P+ A P +G+
Sbjct: 383 KGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLV 442
Query: 470 --------AVPTSSASIP--VTSSVSDPGVGSISPASPK-ISLAPTDVKELSTKEPGRTL 518
A PT++ + V+ +S + +I P SP + +AP KE ST + TL
Sbjct: 443 VTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPST-QVATTL 501
Query: 519 ---------EPQELARIAGKVPGLQNEQKRFQLEELRKFGAQF---------KLQPS--- 557
+P++L + V QK Q GA F K P+
Sbjct: 502 RIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLP 561
Query: 558 ---SSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPM--GSPVSSKTESVSDKEDKPPL 612
++P+NS E P E + EP+ G P SS T + +
Sbjct: 562 LVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLG-VNSSASV 620
Query: 613 APSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTL------------- 659
+ GP+ P S +P V E D VA K T
Sbjct: 621 IKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGT 680
Query: 660 ------NPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISY 713
N KE T L S + P +P P+ P ++ A P+
Sbjct: 681 VSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLA-------PEIPKS 733
Query: 714 IPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAA 773
+P + PA P S + P + S AS+ + A
Sbjct: 734 VPSPSLPPAGTPPGTKKVD-GISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLAD 792
Query: 774 AGPPL-VAATPYSSYIPYNPQQFPGQPAMMQPMAHY--PSQPVFAPMLQSNPRMLTSGSH 830
+ PL V+ +P + P G P+ + P PV A L N
Sbjct: 793 SPSPLGVSVSPQTK----RPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKD 848
Query: 831 PQAIVSSSTPQYPSAEQPTPQALY-----------------ATVHQSYPHHATQLHAHQP 873
A S TP P PTP A+ + V+ +P A +
Sbjct: 849 SPATTHSPTPPSPKGA-PTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQ 907
Query: 874 QPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQ 933
PA + T S P+ A P+P A +P G+ P P A TPPS GP+
Sbjct: 908 APALSMTSSSPKKARATPAPKGIPASPSPK-GAPTP------PAA---TPPSPKGGPATP 957
Query: 934 SPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHP 993
SP+ + PAA P G A P GAP PP P
Sbjct: 958 SPKWAPTPPAAT-----PPSPKG----------------GPATPSPKGAPTPPAAT---P 993
Query: 994 PQSHGGP----PQGA-VPQSGVPALSASTPSPYPYIGHPQVQSHPSQQLPFHPPGN 1044
P GGP P+GA P + P +P+ P+ P+ S P P P G+
Sbjct: 994 PSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPF---PKGASTPPAATPPSPKGS 1046
Score = 42.0 bits (97), Expect = 0.003
Identities = 150/710 (21%), Positives = 230/710 (32%), Gaps = 110/710 (15%)
Query: 405 PSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPP----------PAVGRMYPPRSPKSAA 454
P + A P+ A ++++ +P ++PPP A + P SP + A
Sbjct: 17 PQPQAETAVLPMSSALSVTAALGQPG--PTLPPPCSPAPQQCPLSAANQASPFPSPSTIA 74
Query: 455 PAPISASCPEPPIGSAVPTSSAS--------------IPVTSSVSDP-------GVGSIS 493
P+ P+ G+A+P +A P +++ P G S S
Sbjct: 75 STPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSS 134
Query: 494 PASPKISLAPTDVKELSTKEPGRTLEPQELA------RIAGKVPGLQNEQKRFQLEELRK 547
++LAP V++ S P P +A I P +E K L K
Sbjct: 135 APLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPK----TNLNK 190
Query: 548 FGAQFKLQPSSSPENSLDPFPPRILKEEP---KGKEKEVDGLLTSEPMGSPVSS------ 598
++ P +P PP I+ P + + S P +P ++
Sbjct: 191 VPSEVVPNPKGTPS------PPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASP 244
Query: 599 --KTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKK 656
K ++S P S +GP PP T S PV + K GP
Sbjct: 245 QVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPV--VTSSQKTAGPNTPPDFP 302
Query: 657 STLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQS--GLYSPQYISYI 714
+L + + S S GP S P++ ++ S G P S I
Sbjct: 303 ISLGSHLAPLHQ-----SSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVI 357
Query: 715 PQI----HMGPAVQAPQMYPYPVSNSVPGQQGKYR-GAKGSLPPQRSDQHQPASAPPMMQ 769
P + + PA A P + P GSL S P ++ +
Sbjct: 358 PPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKS 417
Query: 770 AA-AAAGPPLVAATPYSS-----YIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPR 823
+ A PLVA P SS + NP P +A S P + S P
Sbjct: 418 SPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPP-----MSSGPI 472
Query: 824 MLTSGSHPQAIVSSS-TPQYPSAEQPTPQALYATVHQSYPHHATQLHAH--QPQPATTPT 880
+ P A+V + P+ PS + T + + P L + P
Sbjct: 473 SNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDL 532
Query: 881 GSQPQSQHAAP-SPVQHQAGQAPH-------LGSGQPQQNLYHPGALTGTPPSLPPGPSA 932
+ P S AP SP QAG L P+ + T + P +P P A
Sbjct: 533 QTVPASLEGAPFSPA--QAGLTTKKDPTVLPLVQAAPKNSPSFQS--TSSSPEIPLSPEA 588
Query: 933 QSPQSSFPQPAAV-YAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLL 991
+ S +P + P G + A V + G +A P + P V
Sbjct: 589 TLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAF 648
Query: 992 HPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQVQSHPSQQLPFHP 1041
P + A P +GV +A S Y P ++ S HP
Sbjct: 649 --------PLESADP-AGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHP 689
Score = 41.2 bits (95), Expect = 0.005
Identities = 78/327 (23%), Positives = 115/327 (35%), Gaps = 63/327 (19%)
Query: 381 PRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPA 440
P P + SSP P G PS PK + + A T SP P+ PP P
Sbjct: 1571 PATPSSKEASSP-PAVTPSTYKGAPS---PK-ELLIPPAVTSPSPKEAPTPPAVTPPSPE 1625
Query: 441 VGRMYP---------PRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGS 491
G P P +P S +P S + +G+ VP +S +P +
Sbjct: 1626 KGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVL 1685
Query: 492 ISPA--SPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFG 549
++PA S I APT K TK+ T P P +N K
Sbjct: 1686 VAPAPESTPIITAPTR-KGPQTKKSSATSPP------ICPDPSAKNGSK----------- 1727
Query: 550 AQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDK 609
P +++ P P ++++ K D + + +P SK +
Sbjct: 1728 ---------GPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKAST------- 1771
Query: 610 PPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPT 669
PL + + +P S SPPV L P+A + P ++F P+
Sbjct: 1772 -PLTAAAFEKVLPKPESASVSAAPSPPVSL---------PLAPSPVPTL--PPKQQFLPS 1819
Query: 670 KPLLSVNKSTSTPTSPGPRTHSTPSIP 696
P L V +S S P +P P IP
Sbjct: 1820 SPGL-VLESPSKPLAPADEDELLPLIP 1845
Score = 39.7 bits (91), Expect = 0.015
Identities = 35/122 (28%), Positives = 48/122 (39%), Gaps = 9/122 (7%)
Query: 4 PQPLQQPSQPQQPPPTQQA--VARRPPGGTSPPNGGLPGPLATSAAPPGP-----PAAAS 56
P P P+ P PP+ + P G +PP P P + AA P P P AA+
Sbjct: 980 PSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAAT 1039
Query: 57 PCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPG--AAAIGSARGQSTGKGPPQSPVF 114
P + A + L +GA A P P+ P A A + KG P +P
Sbjct: 1040 PPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSP 1099
Query: 115 EG 116
+G
Sbjct: 1100 KG 1101
Score = 39.7 bits (91), Expect = 0.015
Identities = 39/124 (31%), Positives = 46/124 (37%), Gaps = 22/124 (17%)
Query: 4 PQPLQQPSQPQQPPPTQQAVARRPPGG--TSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61
P P P+ P PP+ P GG T PP G P AT +P G A SP P
Sbjct: 1143 PPPKGAPTTPAATPPS-------PKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAP 1195
Query: 62 VAAAGS------GLR----RGAEGILAPQPPPPQQHQERP---GAAAIGSARGQSTGKGP 108
A + GL +GA A PP P+ P GA +A S GP
Sbjct: 1196 TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGP 1255
Query: 109 PQSP 112
P
Sbjct: 1256 ATPP 1259
Score = 39.7 bits (91), Expect = 0.015
Identities = 31/112 (27%), Positives = 39/112 (34%), Gaps = 6/112 (5%)
Query: 3 KPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPV 62
K P P + PP + + GT PP G P T +P G P P P
Sbjct: 1298 KGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTL--PATTPS 1355
Query: 63 AAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQS--TGKGPPQSP 112
+ G EG P P H+ P RG + + KG P SP
Sbjct: 1356 SKGGPTTPSSKEGPTPPAATP--SHKGGPAMTPPSPKRGPAIPSPKGDPTSP 1405
Score = 38.5 bits (88), Expect = 0.033
Identities = 35/116 (30%), Positives = 44/116 (37%), Gaps = 14/116 (12%)
Query: 4 PQPLQQPSQPQQPPPTQQAVARRPP--GGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61
P P P P PP+ + PP G + P P P A PP A +P P
Sbjct: 1097 PSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP 1156
Query: 62 VAAAGSGLR----RGAEGILAPQPPPPQQHQERPGAAAIGSARG-QSTGKGPPQSP 112
+ G GL +GA A PP P+ G A S +G +T P SP
Sbjct: 1157 PSPKG-GLATPPPKGAPTTPAATPPSPK------GGLATPSPKGAPTTPAATPPSP 1205
Score = 38.5 bits (88), Expect = 0.033
Identities = 34/113 (30%), Positives = 47/113 (41%), Gaps = 11/113 (9%)
Query: 4 PQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGP-LATSAAPPGPPAAASPCLGPV 62
P P P+ P PP+ + G +PP+ G P P + T +P G PA + P P
Sbjct: 1258 PPPKGAPTPPAATPPSLKG------GLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPT 1311
Query: 63 -AAAGSGLRRGAEGILAPQ--PPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112
AA +G+ G P+ P PP P A S+ KG P +P
Sbjct: 1312 PPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSS-KGGPTTP 1363
Score = 36.6 bits (83), Expect = 0.13
Identities = 35/119 (29%), Positives = 42/119 (35%), Gaps = 19/119 (15%)
Query: 4 PQPLQQPSQPQQPPPTQQA--VARRPPGGTSPPNGGLPGPLATSAAP-----PGPPAAA- 55
P P P+ P PP+ + P +PP P P A P P PPAA
Sbjct: 934 PSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATP 993
Query: 56 -SPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQST-GKGPPQSP 112
SP GP + G AP PP + AA +G ST P SP
Sbjct: 994 PSPKGGPATPSPKG---------APTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSP 1043
Score = 36.6 bits (83), Expect = 0.13
Identities = 34/119 (28%), Positives = 41/119 (34%), Gaps = 19/119 (15%)
Query: 4 PQPLQQPSQPQQPPPTQQ---AVARRPPGGTSPPNGGLPGPLATSAAP-----PGPPAAA 55
P P + P PP+ + A P G + P LP P A P P PPAA
Sbjct: 1027 PFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAAT 1086
Query: 56 --SPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112
SP GP + G AP PP + G A +T P SP
Sbjct: 1087 PPSPKGGPATPSPKG---------APMPPAATPPSPKGGLATPPHKGAPTTPAATPPSP 1136
Score = 36.6 bits (83), Expect = 0.13
Identities = 33/121 (27%), Positives = 43/121 (35%), Gaps = 9/121 (7%)
Query: 4 PQPLQQPSQPQQPPPTQQA--VARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61
P P P+ P PP+ + P G + P P P A PP A P P
Sbjct: 1212 PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATP 1271
Query: 62 VAAAGSGL----RRGAEGILAPQPPPPQ--QHQERPGAAAIGSARGQSTGKGPPQSPVFE 115
+ G GL +GA PP P+ P A A + KG P +P +
Sbjct: 1272 PSLKG-GLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPK 1330
Query: 116 G 116
G
Sbjct: 1331 G 1331
Score = 36.2 bits (82), Expect = 0.17
Identities = 27/105 (25%), Positives = 36/105 (34%), Gaps = 9/105 (8%)
Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAA 65
P P PPP A PP T P G P AT+ + G P S GP A
Sbjct: 1317 PPSPKGSPGTPPPKG---APTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPA 1373
Query: 66 GSGLRRGAEGILAPQP------PPPQQHQERPGAAAIGSARGQST 104
+ +G + P P P P+ P + + +T
Sbjct: 1374 ATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPAT 1418
Score = 35.8 bits (81), Expect = 0.22
Identities = 62/260 (23%), Positives = 98/260 (37%), Gaps = 39/260 (15%)
Query: 796 PGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQAL-Y 854
PG+ P Q + P ++ ++S A + P P P PQ
Sbjct: 2 PGEATETVPATE---QELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPL 58
Query: 855 ATVHQSYPHHA------TQLHAHQPQPAT---TPTGSQPQSQHAAPSPVQHQAGQAPHLG 905
+ +Q+ P + T L PQ ++ P G+ P++ P+ + A L
Sbjct: 59 SAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAA-LA 117
Query: 906 SGQPQQNLYHPGALTGTPPSLPP------GPSAQSPQSSFP-----QPAAVYAIHHQQLP 954
P + P L GTP S P P + S+FP P +V +
Sbjct: 118 LASP---MIAP-TLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSV- 172
Query: 955 HGFTNMAHVTQAHVQTGITAAPP---PHP-GAPHPPQVMLLHPPQSHGGPPQGAVPQSGV 1010
T A + + +T + P P+P G P PP ++ P H P ++ QSGV
Sbjct: 173 --ITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVP--YHCVTPMASI-QSGV 227
Query: 1011 PALSASTPSPYPYIGHPQVQ 1030
+L +TP+ I PQV+
Sbjct: 228 ASLPQTTPTTTLAIASPQVK 247
Score = 35.0 bits (79), Expect = 0.37
Identities = 37/125 (29%), Positives = 45/125 (36%), Gaps = 24/125 (19%)
Query: 4 PQPLQQP------SQPQQ----PPPTQQAVARRPPGGTSPPNGGLPGPLATSAAP----- 48
P P Q P S P++ P P + P G +PP P P A P
Sbjct: 903 PAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWA 962
Query: 49 PGPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKG- 107
P PPAA P P + +GA A PP P+ G A S +G T
Sbjct: 963 PTPPAATPP--SPKGGPATPSPKGAPTPPAATPPSPK------GGPATPSPKGAPTPPAV 1014
Query: 108 PPQSP 112
P SP
Sbjct: 1015 TPPSP 1019
Score = 35.0 bits (79), Expect = 0.37
Identities = 34/120 (28%), Positives = 43/120 (35%), Gaps = 18/120 (15%)
Query: 10 PSQPQQPPPTQQA--VARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGS 67
P+ P PP+ + P G PP P P A PP A +P P + G
Sbjct: 1080 PTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKG- 1138
Query: 68 GLR----RGAEGILAPQP---------PPPQQHQERPGAAAIGSARGQST--GKGPPQSP 112
GL +GA A P PPP+ P A G +T KG P +P
Sbjct: 1139 GLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1198
Score = 35.0 bits (79), Expect = 0.37
Identities = 28/121 (23%), Positives = 43/121 (35%), Gaps = 7/121 (5%)
Query: 4 PQPLQQPSQPQQPPPTQQAVARRP---PGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
P P P+ P P + + P G +P G L P T + PA ++P G
Sbjct: 1396 PSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGG 1455
Query: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120
P + +G + A PP P++ A S + P +P V +
Sbjct: 1456 PATPSS----KGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPS 1511
Query: 121 S 121
S
Sbjct: 1512 S 1512
Score = 34.7 bits (78), Expect = 0.48
Identities = 32/127 (25%), Positives = 41/127 (32%), Gaps = 20/127 (15%)
Query: 4 PQPLQQPSQPQQPPPTQQA--VARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61
P P P+ P PP+ + P G + P P P A P A +P P
Sbjct: 1189 PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP 1248
Query: 62 VAAAGSGLRRGAEGILAPQPP-------------PPQQHQERPGAAAIGSARG---QSTG 105
+ G +G AP PP PP + P S +G S
Sbjct: 1249 PSPKGGPATPPPKG--APTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPP 1306
Query: 106 KGPPQSP 112
KG P P
Sbjct: 1307 KGAPTPP 1313
Score = 32.0 bits (71), Expect = 3.1
Identities = 25/98 (25%), Positives = 34/98 (34%), Gaps = 6/98 (6%)
Query: 16 PPPTQQAVARRPP-GGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAE 74
PP + A PP G +PP P P + PP A P + P + G+
Sbjct: 1294 PPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATT 1353
Query: 75 GILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112
P P + AA S +G GP +P
Sbjct: 1354 PSSKGGPTTPSSKEGPTPPAATPSHKG-----GPAMTP 1386
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 98.6 bits (244), Expect = 3e-20
Identities = 191/778 (24%), Positives = 269/778 (34%), Gaps = 123/778 (15%)
Query: 357 REGP-RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRP 415
R GP R S + RP S R P N+SPGP S G G +R P Q+
Sbjct: 76 RAGPTRSAGTSSRNPASRPPASGRGERAPP-AKNTSPGPVSSP-GRASGTTRPGPLGQKG 133
Query: 416 LR---------GAKT-------LSSPSNRP-SGETSVPPPPAVGRMYPPRSPKSAAPAPI 458
LR G T LS+ + R SG T P PA+ R + P P
Sbjct: 134 LRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPA 193
Query: 459 SASCPEPPI-GSAVPTSSASIPVTSSVS-------DPGVGSISPASPKISLAPTDVKELS 510
++ P PP G SSAS T+ S G G PAS +S + T + +
Sbjct: 194 PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA 253
Query: 511 TKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQ-----------------FK 553
P P+ A + P + Q+ RK A K
Sbjct: 254 RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTK 313
Query: 554 LQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLA 613
+P P+N+ P P + P L T P+ P S S+ P
Sbjct: 314 ARPVPPPDNAATPLPATLPPSPP---------LATPLPLAPPSPSAPPSLQTLPSPPATP 364
Query: 614 PSGGTEGPEQPPPPC-PSQTGSPPVGL-----IKGEDKDEGPVAEQVKKSTLNPNAKEFN 667
PS PP PS PP+ + P+A ++T + +
Sbjct: 365 PSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQ 424
Query: 668 PTKPLLSVN--KSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAV-- 723
T L+++ ++ ++ TSP + P P L A S SP Q + PAV
Sbjct: 425 ATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPL-----QTSLSPAVSP 479
Query: 724 -QAP-QMYPYPVSNSVPGQQGKYRGAKGSLPPQRSD--------QHQPAS--APPMMQAA 771
+P ++P +S+ + + +PP + Q PAS PP+
Sbjct: 480 LSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLP 539
Query: 772 AAAGPPLVAA-----TPYSSYIPYN---PQQFPGQPAMMQPMAHYPSQ----PVFAPMLQ 819
+ A PPL A TP+ P P Q P P + P PS P AP
Sbjct: 540 SLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSP-LTTPPPETPSSIATPPPQAPPAL 598
Query: 820 SNPRMLTSGSHPQAIVSSSTPQY------------PSAEQPTPQALYATVHQSYPHHATQ 867
++P + S P + +++ PQ PS P + AT P +A
Sbjct: 599 ASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAP-NALA 657
Query: 868 LHAHQP--QPATTPTGSQPQSQHAAP--SPVQHQAGQAPHLGSGQPQQNLYHPGALTGTP 923
+H Q P +P P S A+P SP QAP + P Q + +P
Sbjct: 658 VHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ-------VPPSP 710
Query: 924 PSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAP 983
P+ PP + +P P P A + P M+ + A PP P
Sbjct: 711 PASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPP 770
Query: 984 HPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQVQSHPSQQLPFHP 1041
PP + + P PP A P P L A P + G Q PS LP P
Sbjct: 771 SPPASLPMSPLAK---PPPQAPPALATPPLQALPSPPASFPG--QAPFSPSASLPMSP 823
Score = 87.4 bits (215), Expect = 6e-17
Identities = 165/730 (22%), Positives = 230/730 (31%), Gaps = 130/730 (17%)
Query: 334 GSGRESPSLASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPG 393
G G + P+ S PL R GP S+RG PR P H P
Sbjct: 231 GGGLQRPASRSLSSSATPLSSPARSGP-------SARG--------TPRAPAHPSQPKPK 275
Query: 394 PGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYP---PRSP 450
R P R + L++PS + VPPP P P SP
Sbjct: 276 GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSP 335
Query: 451 KSAAPAPISASCPE-PPIGSAVPTSSASIPVTS--SVSDPGVGSISPASPKISLAPTDVK 507
A P P++ P PP +P+ A+ P + S++ P + A P + P
Sbjct: 336 PLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPM----QAPPSLQTIPPIQV 391
Query: 508 ELSTKEPGRTLEPQELARIAGKVP---GLQNEQKRFQLEELRKFGAQFKLQPSSSPENSL 564
S P P LA + + G Q + Q L S P ++
Sbjct: 392 PHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTP 451
Query: 565 DPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT-----ESVSDKEDKPPLAPSGGTE 619
PP + P + P SP+SS +++S P AP
Sbjct: 452 PDSPPL---QAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLI 508
Query: 620 GP--EQPPPPCPSQTGSPPVGLIKGEDKDEGPVAE---QVKKSTLNPNAKEFNPTKPLLS 674
P E P +PP L ++ +A Q + L E P
Sbjct: 509 MPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCP 568
Query: 675 VNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVS 734
+ S T+P P T S+ + P A + L SP + +P + P P P ++
Sbjct: 569 LQAPPSPLTTPPPETPSSIATPPPQAPPA-LASPP-LQGLPSPPLSPLATPPPQAPPXLA 626
Query: 735 NSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQ 794
LPP ++ PAS PP+ A + A + P++P
Sbjct: 627 ----------------LPPLQAPPSPPAS-PPLSPLATPSPQAPNALAVHLLQAPFSPPP 669
Query: 795 FPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALY 854
P A P A P P P Q+ P + +S P PSA P PQA
Sbjct: 670 SPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSA-TPPPQA-- 726
Query: 855 ATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLY 914
P P P P S A+P P+ A P +
Sbjct: 727 ------------------PPPLAAPPLQVPPSPPASP-PMSPSATPPPRV---------- 757
Query: 915 HPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITA 974
P L P +PP P A P S +P
Sbjct: 758 -PPLLAAPPLQVPPSPPASLPMSPLAKP-------------------------------- 784
Query: 975 APPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQVQSHPS 1034
P P PP L PP S G + P + +P +TP P P V + P
Sbjct: 785 PPQAPPALATPPLQALPSPPASFPGQAPFS-PSASLPMSPLATPPPQA----PPVLAAPL 839
Query: 1035 QQLPFHPPGN 1044
Q+P PP +
Sbjct: 840 LQVPPSPPAS 849
Score = 81.3 bits (199), Expect = 4e-15
Identities = 168/709 (23%), Positives = 247/709 (34%), Gaps = 95/709 (13%)
Query: 357 REGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPL 416
R+ + G + PGL L PR P SP P P ++P A R L
Sbjct: 5 RDKAKAGAAARTPAARAPGL--LTPRPP-----GSPRP----------PPPVTPAALRVL 47
Query: 417 RGAKTLSSP--SNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTS 474
A + + R G P + R P RS +++ P S P G P +
Sbjct: 48 GAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRP-PASGRGERAPPA 106
Query: 475 SASIPVTSSVSDPG-------VGSISPASPKISLAPTDVKELSTKEPGRTLEPQELAR-I 526
+ P VS PG G + +IS T + +T+ P R+ R
Sbjct: 107 KNTSP--GPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDT 164
Query: 527 AGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGL 586
+G PG + R G + L P S P PP E P+
Sbjct: 165 SGPTPGTPSPA---MARRSRAAGTEVGLP---RPAPSARPRPPT---EGPRKSVSSASEH 215
Query: 587 LTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGP-EQPPPPCPSQTGSPPVGLIKGEDK 645
T+EP SP + + S +P + P P PS G+P + K
Sbjct: 216 STTEP--SPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPK 273
Query: 646 DEGPVAEQVKKSTLNPNAKEFNPTK-PLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSG 704
+G + ++ + P K+ P PL S +T +P+ R P +
Sbjct: 274 PKG--LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATL 331
Query: 705 LYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASA 764
SP + +P P+ P + P + P Q PP + P A
Sbjct: 332 PPSPPLATPLPLAPPSPSAP-PSLQTLPSPPATPPSQA---------PPSMTTP--PMQA 379
Query: 765 PPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRM 824
PP +Q PP+ P+S P Q P P + + S + +P LQ+
Sbjct: 380 PPSLQTI----PPI--QVPHSLTSP--SLQAPPSPLALSSLQATTS--LGSPTLQATHSF 429
Query: 825 LTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQP 884
LT S Q S ++P P++ P L A + L A P + P
Sbjct: 430 LTM-SPRQTQASLTSPSRPASTPPDSPPLQAPL---------SLPASPPLQTSLSPAVSP 479
Query: 885 QSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAA 944
S P+Q + A H P +L P T + SL P PS Q+P +S P
Sbjct: 480 LSSPLTIHPLQALSSLASHSPQA-PLSSLIMPPLETQS--SLAP-PSLQTPPASLTTPP- 534
Query: 945 VYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHP--------PQVMLLHPPQS 996
+ + P T A +T H++T AP P P P P + PPQ+
Sbjct: 535 LENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQA 594
Query: 997 H---GGPPQGAVPQSGVPALSASTPSPYPYIGHPQVQSHPSQQLPFHPP 1042
PP +P + L+ P P + P +Q+ PS P PP
Sbjct: 595 PPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSP--PASPP 641
Score = 47.0 bits (110), Expect = 9e-05
Identities = 72/304 (23%), Positives = 108/304 (35%), Gaps = 34/304 (11%)
Query: 374 PGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSR-----MSPKAQRPLRGAKTLSSPSNR 428
P + PP P P A + PS MSP A P R L++P +
Sbjct: 708 PSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQ 767
Query: 429 --PSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPI---GSAVPTSSASIPVTSS 483
PS S+P P PP++P + A P+ A P PP G A + SAS+P++
Sbjct: 768 VPPSPPASLPMSPLAKP--PPQAPPALATPPLQA-LPSPPASFPGQAPFSPSASLPMSPL 824
Query: 484 VSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGK------VPGLQNEQ 537
+ P A+P + + P+ + + P R P ++G PG
Sbjct: 825 ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPP 884
Query: 538 KRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVS 597
R L P + +S P L+ G E G S P + ++
Sbjct: 885 SRSPSSTLS--------GPDLAGHSSSATSTPEELRGYDSGPE---GGAAASPPPDAELA 933
Query: 598 SKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKS 657
+ + + PPLA G P P P TG + + EGP +
Sbjct: 934 ACHPAAWSRGPAPPLA----FRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPG 989
Query: 658 TLNP 661
L+P
Sbjct: 990 ALDP 993
Score = 46.2 bits (108), Expect = 2e-04
Identities = 43/134 (32%), Positives = 51/134 (38%), Gaps = 30/134 (22%)
Query: 4 PQPLQQPSQP--QQPPPTQQAVA----RRPPGGTSPPNGGLP----GPLATS-------- 45
P PLQ P P PP T ++A + PP SPP GLP PLAT
Sbjct: 566 PCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXL 625
Query: 46 -----AAPPGPPAAASPCLGPVAAAGSGLRRG-----AEGILAPQPPPPQQHQERPGAAA 95
APP PP ASP L P+A + +P P PP Q P A+
Sbjct: 626 ALPPLQAPPSPP--ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 683
Query: 96 IGSARGQSTGKGPP 109
S + PP
Sbjct: 684 PVSPSATPPSQAPP 697
Score = 37.7 bits (86), Expect = 0.057
Identities = 33/123 (26%), Positives = 43/123 (34%), Gaps = 18/123 (14%)
Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTS------------PPNGGLPGPLATSAAPPGPPA 53
PLQ P P PP P + PP+ + P + A+PP P+
Sbjct: 629 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 688
Query: 54 AASPCLGPVAAAGSGLR----RGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPP 109
A P P + A L+ A ++P PP Q P AA S PP
Sbjct: 689 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP--QAPPPLAAPPLQVPPSPPASPP 746
Query: 110 QSP 112
SP
Sbjct: 747 MSP 749
Score = 37.0 bits (84), Expect = 0.097
Identities = 39/122 (31%), Positives = 48/122 (39%), Gaps = 30/122 (24%)
Query: 13 PQQPP--PTQQAVARRPPGGTSPPNGGLPGP---LATSAAPPGPP--AAASPCLGPVAAA 65
P PP PT QA RRPP T P+ + GP LA + PP PP + +S GP A
Sbjct: 843 PPSPPASPTLQA-PRRPP--TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAG 899
Query: 66 GS-----------GLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVF 114
S G G EG A PPP A + + + +GP F
Sbjct: 900 HSSSATSTPEELRGYDSGPEGGAAASPPPD---------AELAACHPAAWSRGPAPPLAF 950
Query: 115 EG 116
G
Sbjct: 951 RG 952
Score = 36.2 bits (82), Expect = 0.17
Identities = 34/112 (30%), Positives = 43/112 (38%), Gaps = 6/112 (5%)
Query: 3 KPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAP-PGPPAAASPCLGP 61
KP+ LQ PQ PP + A P +SP P P T A P P P AA+P P
Sbjct: 273 KPKGLQALRPPQVTPPRKDAAPALGPLSSSPL--ATPSPSGTKARPVPPPDNAATPL--P 328
Query: 62 VAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPP-QSP 112
S + P P P Q P A ++ + PP Q+P
Sbjct: 329 ATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAP 380
Score = 33.5 bits (75), Expect = 1.1
Identities = 32/113 (28%), Positives = 39/113 (34%), Gaps = 24/113 (21%)
Query: 2 LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLP--GPLATSAAPPGPPAAASPCL 59
L PLQ P P PP + PP PP P P + A+PP P+A P
Sbjct: 699 LAAPPLQVPPSPPASPPMSPSAT--PPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPR 756
Query: 60 GPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112
P A L+ + P PP S K PPQ+P
Sbjct: 757 VPPLLAAPPLQ------VPPSPP--------------ASLPMSPLAKPPPQAP 789
Score = 32.3 bits (72), Expect = 2.4
Identities = 38/130 (29%), Positives = 48/130 (36%), Gaps = 22/130 (16%)
Query: 2 LKPQPLQQPSQPQQPPPTQQAVA---RRPPGGTSPPNGGLPGPLATS-----AAPP--GP 51
L PLQ P P PP + R PP +PP P P A+ A PP P
Sbjct: 730 LAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAP 789
Query: 52 PAAASPCL-----GPVAAAGSG-LRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTG 105
PA A+P L P + G A ++P PP P A + +A
Sbjct: 790 PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP------PQAPPVLAAPLLQVP 843
Query: 106 KGPPQSPVFE 115
PP SP +
Sbjct: 844 PSPPASPTLQ 853
Score = 31.6 bits (70), Expect = 4.1
Identities = 29/91 (31%), Positives = 34/91 (37%), Gaps = 13/91 (14%)
Query: 16 PPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEG 75
PPP + A P + P PLA AP G P P GP +A G EG
Sbjct: 926 PPPDAELAACHPAAWSRGP----APPLAFRGAP-GAPLPWPPATGPGSADGLCTIYETEG 980
Query: 76 ILAPQPPPPQQHQERPGAAAIGSARGQSTGK 106
P+ PGA G + G S GK
Sbjct: 981 --------PESATPAPGALDPGPSPGTSGGK 1003
Score = 30.4 bits (67), Expect = 9.1
Identities = 20/73 (27%), Positives = 29/73 (39%), Gaps = 2/73 (2%)
Query: 11 SQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLR 70
S P + P+ + R P + P GL PP AA P LGP++++
Sbjct: 250 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAA--PALGPLSSSPLATP 307
Query: 71 RGAEGILAPQPPP 83
+ P PPP
Sbjct: 308 SPSGTKARPVPPP 320
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 96.7 bits (239), Expect = 1e-19
Identities = 171/713 (23%), Positives = 245/713 (34%), Gaps = 117/713 (16%)
Query: 381 PRGPH--HLDNSSPGP-GSEARGINGGPSRMSPKAQRPLRGAKTL-----SSPSNRPSGE 432
P+G H + PGP EA+ + ++ P+ + PL L SP + P E
Sbjct: 396 PKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEE 455
Query: 433 TSVPPPPAVGRMYPPRSPKSAAPAP----ISASCPEPPIGSAVPTSSASIPVTSSVSDPG 488
+ PPP R+ PP A+P P +S E P+ S S P SS P
Sbjct: 456 SPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSP- 514
Query: 489 VGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKF 548
SP SP P+ E P E L+ P + EEL
Sbjct: 515 -LEESPLSPPEESPPSPALETPLSPPP---EASPLS------PPFEESPLSPPPEELPTS 564
Query: 549 GAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGL--------LTSEPMGSPVSSKT 600
+ S PE S PP +E P E L L+ P SP+S
Sbjct: 565 PPPEASRLSPPPEESPMSPPP---EESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPP 621
Query: 601 ES--VSDKEDKPPLAPSGGTEGPEQPPP--------PCPSQTGSPPVGLIKGEDKDEGPV 650
E+ +S + P++P E P PPP P S+ PP +E P
Sbjct: 622 EASRLSPPPEDSPMSPP-PEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPT 680
Query: 651 AEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGL-YSPQ 709
+ + S L+P E +PT P +P SP P S S+P+ + L PQ
Sbjct: 681 SPPPEASRLSP-PPEDSPTSP-----PPEDSPASPPPE-DSLMSLPLEESPLLPLPEEPQ 733
Query: 710 YISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQH-QPASAPPMM 768
H+ P + P + P P + L PQ + H P P +
Sbjct: 734 LCPRSEGPHLSPRPEEPHLSPRP--------------EEPHLSPQAEEPHLSPQPEEPCL 779
Query: 769 QAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQP-MAHYPSQPVFAPMLQS------- 820
A P ++ ++ P++ P +P ++ P +P +P +
Sbjct: 780 --CAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQS 837
Query: 821 -----NPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQP 875
+PR S P+ P P E+P + + P L +P
Sbjct: 838 EEPCLSPRPEESHLSPEL---EKPPLSPRPEKPPEEPGQCPAPEELP-----LFPPPGEP 889
Query: 876 ATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQP--QQNLYHPGALTGTPPSLPP----- 928
+ +P +P P+ + P SG+P L P L PP L P
Sbjct: 890 SLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPL---PPPLSPIITAA 946
Query: 929 GPSAQSPQSSFPQPAAVYAIHHQQLPHGF----TNMAHVTQAHVQTGITAAP---PPHPG 981
P A SP P + P T ++ +A+ P PP PG
Sbjct: 947 APPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPG 1006
Query: 982 APHPPQVMLLH---PPQ-----SHGGPPQGAVP-QSGVPALSASTPSPYPYIG 1025
+P P +L PPQ H PQ + P Q PAL S PSP IG
Sbjct: 1007 SPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIG 1059
Score = 55.5 bits (132), Expect = 3e-07
Identities = 140/580 (24%), Positives = 198/580 (34%), Gaps = 119/580 (20%)
Query: 487 PG-VGSISPAS-PKISL-APTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLE 543
PG +GS PA+ P I + +PT LST G P AG VPG + + F
Sbjct: 2110 PGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPP------AGSVPGPDSPGELFL-- 2161
Query: 544 ELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESV 603
K Q Q S L P P EP+ T+ P P S T +
Sbjct: 2162 ---KLPPQVPAQVPSQDPFGLAPAYPL----EPR--------FPTAPPTYPPYPSPTGAP 2206
Query: 604 SDKEDKPPLAPSGGTEGPEQP------PPPCPSQTGSPPVGLIKGEDKD-------EGPV 650
+ +PP+ + G QP PP P S P +K E P
Sbjct: 2207 A----QPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPG 2262
Query: 651 AEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQY 710
K S + F ++ L V K +SP ++ P++ + + SG +
Sbjct: 2263 VGGGKASEPLLSPPPFGESRKALEVKKEELGASSP---SYGPPNLGFVDSPSSGTHLGGL 2319
Query: 711 ISYIPQIHMGPAV-QAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQ 769
P + P +A Q+ P + Q+ A PP D +P S
Sbjct: 2320 ELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGS-----Y 2374
Query: 770 AAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGS 829
A PPL TP PQ P + P PS P + ++P+ +S
Sbjct: 2375 TDPYAQPPL---TP-------RPQPPPPESCCALPPRSLPSDPF--SRVPASPQSQSSSQ 2422
Query: 830 HPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHA 889
P TP+ SAE P + P+ P P P+ Q
Sbjct: 2423 SPL------TPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFA-PLHKPPRPQ-- 2473
Query: 890 APSPVQHQAGQAPH--LGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYA 947
P V +AG H LG+G G P +LP GP+ +
Sbjct: 2474 -PPEVAFKAGSLAHTSLGAG-------------GFPAALPAGPAGEL------------- 2506
Query: 948 IHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPP-QGAVP 1006
H ++P G V++ T A G P P + PQ+ G P + VP
Sbjct: 2507 --HAKVPSG------QPPNFVRSPGTGA---FVGTPSPMRFTF---PQAVGEPSLKPPVP 2552
Query: 1007 QSGVPALSA--STPSPYPYIGHPQVQSHPSQQLPFHPPGN 1044
Q G+P S P P +G PQ ++ FHP G+
Sbjct: 2553 QPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGS 2592
Score = 55.1 bits (131), Expect = 3e-07
Identities = 141/594 (23%), Positives = 202/594 (34%), Gaps = 98/594 (16%)
Query: 422 LSSPSNRPSGETSVPPPP-AVGRMYPPRSP-----KSAAPAPISASCP---EPPIGSAVP 472
++ ++RP+ +PP P A+G P +P PA +S S +PP GS
Sbjct: 2093 IARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPG 2152
Query: 473 TSSAS---------IPVTSSVSDP-GVGSISPASPKISLAPTDVKELSTKEPGRTLEPQE 522
S +P DP G+ P P+ AP + G +P
Sbjct: 2153 PDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPT-GAPAQPPM 2211
Query: 523 LARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRI----LKEEPK- 577
L A PG Q E S+P+ L P P + + E P
Sbjct: 2212 LG--ASSRPGAG------QPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGV 2263
Query: 578 GKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPV 637
G K + LL+ P G S K V KE+ +PS G PP SP
Sbjct: 2264 GGGKASEPLLSPPPFGE--SRKALEVK-KEELGASSPSYG--------PPNLGFVDSPSS 2312
Query: 638 GLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPV 697
G G + + P V K+ L P A + P P L + P P P PS P
Sbjct: 2313 GTHLGGLELKTP---DVFKAPLTPRASQVEPQSPGLGLR-----PQEPPPAQALAPSPP- 2363
Query: 698 LTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQ---GKYRGAKGSLPPQ 754
++ P SY P PQ P ++P + + S P
Sbjct: 2364 ---SHPDIFRPG--SYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPAS-PQS 2417
Query: 755 RSDQHQPASAPPMMQAAAAAGPPLVAATP-YSSYIPYNPQQFPGQPAMMQPMA--HYPSQ 811
+S P + P+ A P TP + S PY+ P +P P A H P +
Sbjct: 2418 QSSSQSPLTPRPLSAEAFCPSP----VTPRFQSPDPYSRP--PSRPQSRDPFAPLHKPPR 2471
Query: 812 PVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAE--------QPTPQALYATVHQSYPH 863
P P + L S ++ P P+ E QP P + + ++
Sbjct: 2472 PQ-PPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQP-PNFVRSPGTGAFVG 2529
Query: 864 HATQLHAHQPQPATTPTGSQPQSQHAAPSP--VQHQAGQAPHLGSGQPQQNLYHPGALTG 921
+ + PQ P+ P Q P P + G P LG +PQ Y
Sbjct: 2530 TPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLG--KPQSTNYTVATGNF 2587
Query: 922 TPPSLPPGPSAQS-----------PQSSFPQPAAVYAIHHQQLPHGFTNMAHVT 964
P P GPS+ S P S P PA ++ + L HG + + +T
Sbjct: 2588 HPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPY--LSHGASQRSGIT 2639
Score = 53.9 bits (128), Expect = 8e-07
Identities = 162/801 (20%), Positives = 262/801 (32%), Gaps = 142/801 (17%)
Query: 308 QYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIP-----LPQRVREGPRG 362
+YR + + + ++++HSAV + L G+ +P PQ G G
Sbjct: 3594 EYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQGPPGGQAG 3653
Query: 363 GVRCSSSRGGRPGLSSLP-----------------------PRG---PHHLDNSSPGPGS 396
G+R + PG P P G P +L S GP S
Sbjct: 3654 GLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLALRSLGPDS 3713
Query: 397 ---EARGINGGPSRMS-----------PKAQRPLRGAKTLSSPSNR-PSGETSVPPPPAV 441
+ R + RM + Q+ L G + + P +T+ P
Sbjct: 3714 RLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKP 3773
Query: 442 GRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISL 501
+ PP S + +S P+ P G P A + G++ P P +
Sbjct: 3774 QGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVL------QQQHPGALGPQGPHRQV 3827
Query: 502 APTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPS---- 557
T + LS+ + L Q + ++ Q +Q++ Q ++ LQ S
Sbjct: 3828 LMTQSRVLSSPQ----LAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSH 3883
Query: 558 -SSPENSLDPFPP-RILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPS 615
P+ S P + L+++ + ++++ + + + + + ++ + L
Sbjct: 3884 SGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQ 3943
Query: 616 GGTE----------GPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKE 665
+ +Q Q +GL+ P +Q ++ L P
Sbjct: 3944 QQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGM-- 4001
Query: 666 FNPTKPLL--------------------SVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGL 705
P KPL +V+ + S+ + GP TH + + T +S
Sbjct: 4002 --PAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMA 4059
Query: 706 YSPQYISYIPQIHMGPAVQAPQMYPYPVSNSV--------PGQQGK-----YRGAKGSLP 752
P + P + + Q P P +S+ PGQQ + + GS
Sbjct: 4060 TEPGEVK--PSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHG 4117
Query: 753 PQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHY--PS 810
S AS+ P + A P V+ + N P QP + +PM + P
Sbjct: 4118 QLGSGSSSEASSVPHLLAQ-----PSVSLGDQPGSMTQNLLG-PQQPMLERPMQNNTGPQ 4171
Query: 811 QPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHA 870
P P+LQS + G P + Q A+ P + L Q Q
Sbjct: 4172 PPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQL 4231
Query: 871 HQPQPAT-TPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPG 929
Q Q TP +P +Q SP+Q G P LG PG TG L G
Sbjct: 4232 QQSQAVRQTPPYQEPGTQ---TSPLQGLLGCQPQLGG--------FPGPQTGPLQELGAG 4280
Query: 930 PSAQSPQ---------SSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAA-PPPH 979
P Q P S+ P V+ P + + Q A PP H
Sbjct: 4281 PRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTH 4340
Query: 980 PGAPHPPQVMLLHPPQSHGGP 1000
PG P PQ L PP P
Sbjct: 4341 PGTP-KPQGPTLEPPPGRVSP 4360
Score = 53.1 bits (126), Expect = 1e-06
Identities = 112/505 (22%), Positives = 157/505 (31%), Gaps = 108/505 (21%)
Query: 341 SLASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPH--------------- 385
SL E +PLP+ + PR S R P LS P PH
Sbjct: 717 SLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEE-PHLSPQAEEPHLSPQPE 775
Query: 386 -----------HLDNSSPGP--GSEARGINGGPS----RMSPKAQRPLRGAKTLSSPSNR 428
HL + GP + ++ P +SP + P + S +
Sbjct: 776 EPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSP 835
Query: 429 PSGETSVPPPPAVGRM-----YPPRSPKSAAPAPISASCPEPPIGSAVP----TSSASIP 479
S E + P P + PP SP+ P CP P P S + +
Sbjct: 836 QSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLL 895
Query: 480 VTSSVSDPGVGSISPASPKISLAPTDVKELSTK-EPGRTLEPQELARIAGKVPGLQNEQK 538
++S+PG +SP ++ L+P+ LS + P L P I P
Sbjct: 896 GEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPP------ 949
Query: 539 RFQLEELRKFGAQFKLQPSSSPENSL--------------------DPFPPRILKEEPKG 578
L L + F + S PE+ L +P PP IL P
Sbjct: 950 --ALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGS 1007
Query: 579 KEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSP--P 636
+L EP+ S + ++ PP S PP P SP P
Sbjct: 1008 PVGPASPIL-MEPLPPQCSPLLQHSLVPQNSPPSQCS---------PPALPLSVPSPLSP 1057
Query: 637 VGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNP--TKPLLSVNKSTSTPT-SPGPRTHSTP 693
+G + G DE + E + P P T PL S S P SP P
Sbjct: 1058 IGKVVGV-SDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFS 1116
Query: 694 SIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQ-QGKYRGAKGSLP 752
+ TA G + AP P P PG + +G+ L
Sbjct: 1117 GLGEDTAPLDG------------------IDAPGSQPEP--GQTPGSLASELKGSPVLLD 1156
Query: 753 PQRSDQHQPASAPPMMQAAAAAGPP 777
P+ P P + A G P
Sbjct: 1157 PEELAPVTPMEVYPECKQTAGQGSP 1181
Score = 50.1 bits (118), Expect = 1e-05
Identities = 70/307 (22%), Positives = 112/307 (36%), Gaps = 34/307 (11%)
Query: 752 PPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQ 811
PP+ S P S PP + PP P +S + P++ P P P A + S+
Sbjct: 443 PPEES----PLSPPP---EESPTSPP-----PEASRLSPPPEELPASPL---PEALHLSR 487
Query: 812 PVFAPMLQSNPRMLTSGSHPQAIVSS---STPQYPSAEQPTPQALYATVHQSYPHHATQL 868
P+ L P P++ S +P P E P AL + S P A+ L
Sbjct: 488 PLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPL--SPPPEASPL 545
Query: 869 HAH------QPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQ---QNLYHP--- 916
P P PT P++ +P P + P P L+ P
Sbjct: 546 SPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEE 605
Query: 917 GALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFT-NMAHVTQAHVQTGITAA 975
L+ P P P ++ + S P + + ++ P ++ ++ V + ++
Sbjct: 606 SPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPP 665
Query: 976 PPPHPGAPHPPQVMLLHPPQ-SHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQVQSHPS 1034
P P +P P + PP+ S PP P S P S ++P P + ++ P
Sbjct: 666 PEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPL 725
Query: 1035 QQLPFHP 1041
LP P
Sbjct: 726 LPLPEEP 732
Score = 45.8 bits (107), Expect = 2e-04
Identities = 162/717 (22%), Positives = 240/717 (33%), Gaps = 148/717 (20%)
Query: 377 SSLPPRGPHHL---DNSSPGP---GSEARGINGGPSRMSPKAQRPLRGAKTLS-SPSNRP 429
+S P GP +L D+ S G G E + + + ++P+A + + L P P
Sbjct: 2294 ASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPP 2353
Query: 430 SGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGV 489
+ P PP+ ++ P S P P+PP P S ++P S SDP
Sbjct: 2354 PAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPP----PPESCCALPPRSLPSDPF- 2408
Query: 490 GSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFG 549
S PASP+ + S++ P L P+ L+ A + RFQ +
Sbjct: 2409 -SRVPASPQ--------SQSSSQSP---LTPRPLSAEAFCPSPVT---PRFQSPDPYS-- 2451
Query: 550 AQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVD---GLLTSEPMGS---PVSSKTESV 603
+P S P+ S DPF P L + P+ + EV G L +G+ P +
Sbjct: 2452 -----RPPSRPQ-SRDPFAP--LHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPA 2503
Query: 604 SDKEDKPPLAP---------SGGTEGPEQP--------------PPPCPSQTGSPPVGLI 640
+ K P +G G P PP P PP G+
Sbjct: 2504 GELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGI- 2562
Query: 641 KGEDKDEGPVAEQVKKSTLNPNAKEFNPT-KPLLSVNKSTST--------PTSPGPRTHS 691
GP + + + F+P+ PL + ST P S P
Sbjct: 2563 -NSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAP 2621
Query: 692 TPSIPVLTAG---QSGLYSPQYISYIPQIHMG--------PAVQAPQMYPYPVS------ 734
S+P L+ G +SG+ SP P MG P Q P M +
Sbjct: 2622 DGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQR 2681
Query: 735 ----------------NSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPL 778
N++ ++ A G++ P S +P+S P + + P
Sbjct: 2682 QRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSS--PAFEQLSRGQTPF 2739
Query: 779 VAATPYSSYIPYNPQQFPGQ---PAMM--QPMAHYPSQPVFAPMLQSNPRMLTSGSHPQA 833
SS + P + G P P P + N R L GS QA
Sbjct: 2740 AGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGS--QA 2797
Query: 834 IVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQ-SQHAAPS 892
+ YP + P Q Q AT + A P+ P+ + A S
Sbjct: 2798 FYQRAP--YPGS-LPLQQQQQQLWQQQQATAATSMRF--AMSARFPSTPGPELGRQALGS 2852
Query: 893 PVQHQAGQAPHLGSGQPQQNLYHPGALT--------GTPPSLPPGPSAQSPQSSFPQPAA 944
P+ + + P G G+P P G P P P PQ P+
Sbjct: 2853 PLAGISTRLP--GPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQR--PRFYP 2908
Query: 945 VYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQV-MLLHPPQSHGGP 1000
V H+ P G +A ++ PP P AP P++ LHP GP
Sbjct: 2909 VSEDPHRLAPEGLRGLA----------VSGLPPQKPSAPPAPELNNSLHPTPHTKGP 2955
Score = 43.9 bits (102), Expect = 8e-04
Identities = 67/306 (21%), Positives = 104/306 (33%), Gaps = 28/306 (9%)
Query: 741 QGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPA 800
QG+ +G + + A P+ +A P L A P + +P P P +
Sbjct: 393 QGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEA--PLNEEMPLLPP--PEESP 448
Query: 801 MMQPMAHYP-SQPVFAPMLQSNPRMLTSGSHPQAI-VSSSTPQYPSAEQPTPQALYATVH 858
+ P P S P A L P L + P+A+ +S + P + P L
Sbjct: 449 LSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPL----- 503
Query: 859 QSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGA 918
S P ++ + P + P S P P +A P +
Sbjct: 504 -SPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEAS---------PLSPPFEESP 553
Query: 919 LTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPP 978
L+ P LP P ++ + S P + + ++ P A + + PP
Sbjct: 554 LSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPE 613
Query: 979 HPGAPHPPQVMLLHPP--QSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQVQSHPSQQ 1036
PP+ L PP S PP P S P +S SP P + S P ++
Sbjct: 614 ESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRL--SPLPVVSR---LSPPPEE 668
Query: 1037 LPFHPP 1042
P PP
Sbjct: 669 SPLSPP 674
Score = 43.9 bits (102), Expect = 8e-04
Identities = 88/358 (24%), Positives = 135/358 (37%), Gaps = 61/358 (17%)
Query: 361 RGGVRCSSSRGGRPGLSSLP---------PRGPHHLDNSSPGPGSEARGINGGPSRMSP- 410
+G + C GG PG + P P+GP L PG+ + G GP +P
Sbjct: 4254 QGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAP---PGALSTGPVLGPVHPTPP 4310
Query: 411 --KAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIG 468
Q P R ++ L SPS++ E +PP P +PK P EPP G
Sbjct: 4311 PSSPQEPKRPSQ-LPSPSSQLPTEAQLPPT-------HPGTPKPQGPT------LEPPPG 4356
Query: 469 SAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAG 528
P A+ + ++ G+G P P +LA T E S+ PG L ++ G
Sbjct: 4357 RVSP---AAAQLADTLFSKGLG---PWDPPDNLAETQKPEQSSLVPG------HLDQVNG 4404
Query: 529 KV--PGLQNEQKRFQLEELRKFGAQ-FKLQPSSSP------ENSLDPFPPR------ILK 573
+V Q K+ EE GAQ K + + P N L PR +L+
Sbjct: 4405 QVVPEASQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLLLQ 4464
Query: 574 EEPKGKEKEVDGLLTSEPMGSPVSSKTES-VSDKEDKPPLAPSGGTEG----PEQPPPPC 628
+ + K ++ SE + + ++ +S ++ E K PS + P P P
Sbjct: 4465 KLLRAKNVQLSTGRGSEGLRAEINGHIDSKLAGLEQKLQGTPSNKEDAAARKPLTPKPKR 4524
Query: 629 PSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPG 686
+ V K K++G A + L T+P ++ N S P G
Sbjct: 4525 VQKASDRLVSSRKKLRKEDGVRASEALLKQLKQELSLLPLTEPAITANFSLFAPFGSG 4582
Score = 39.3 bits (90), Expect = 0.020
Identities = 33/112 (29%), Positives = 43/112 (38%), Gaps = 22/112 (19%)
Query: 1 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
+L + LQQ +Q PP Q+ PG + P GL G PGP G
Sbjct: 4225 LLMQRQLQQSQAVRQTPPYQE------PGTQTSPLQGLLGCQPQLGGFPGPQT------G 4272
Query: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112
P+ G+G P+P P + PGA + G G PP SP
Sbjct: 4273 PLQELGAG----------PRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSP 4314
Score = 34.3 bits (77), Expect = 0.63
Identities = 32/120 (26%), Positives = 43/120 (35%), Gaps = 10/120 (8%)
Query: 2 LKPQPLQQPSQ--PQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCL 59
L+ PL P + P PPP + SPP P P + P PP ASP
Sbjct: 489 LEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALET--PLSPPPEASPLS 546
Query: 60 GPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS----PVFE 115
P S L E + PP + P + + +S PP++ P FE
Sbjct: 547 PPFEE--SPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFE 604
Score = 33.9 bits (76), Expect = 0.82
Identities = 30/97 (30%), Positives = 42/97 (43%), Gaps = 21/97 (21%)
Query: 2 LKPQ-PLQQPSQPQQPPPTQQAVARRPP--GGTSPPNGGLPGPLATSAAPPG----PPAA 54
L+P+ P P+ P P PT +PP G +S P G PG T+ PPG P+
Sbjct: 2185 LEPRFPTAPPTYPPYPSPT--GAPAQPPMLGASSRPGAGQPGEFHTT--PPGTPRHQPST 2240
Query: 55 ASPCLGP----------VAAAGSGLRRGAEGILAPQP 81
P L P + G G + +E +L+P P
Sbjct: 2241 PDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPP 2277
Score = 33.9 bits (76), Expect = 0.82
Identities = 85/391 (21%), Positives = 128/391 (32%), Gaps = 66/391 (16%)
Query: 561 ENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEG 620
+N++DP + E +G G P+ + ++ + E KP L+
Sbjct: 4026 QNTVDP---AVSSEATEGPSTHQGG-----PLAIGTTPESMATEPGEVKPSLSGDSQLLL 4077
Query: 621 PEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQV---KKSTLNPNAKEFNPTKPLLSVNK 677
+ P P PS P + G+ + + + L + + P L
Sbjct: 4078 VQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQP 4137
Query: 678 STSTPTSPGPRTHST--PSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSN 735
S S PG T + P P+L PQ GP +Q+ Q P
Sbjct: 4138 SVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQ------PPKPGPVLQSGQGLPGVGIM 4191
Query: 736 SVPGQ-QGKYRGAKGSLP------PQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYI 788
GQ + + +G P PQ+ Q Q +Q + A V TP
Sbjct: 4192 PTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQA-----VRQTP----- 4241
Query: 789 PYNPQQFPG-QPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQ 847
P Q PG Q + +Q + Q P Q+ P Q + + PQ P
Sbjct: 4242 ---PYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPL--------QELGAGPRPQGPP-RL 4289
Query: 848 PTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSG 907
P P +T P H T P ++P + SQ +PS Q P
Sbjct: 4290 PAPPGALSTGPVLGPVHPTP-------PPSSPQEPKRPSQLPSPSSQLPTEAQLPPT--- 4339
Query: 908 QPQQNLYHPGALTGTPPSLPPGPSAQSPQSS 938
HPG P+L P P SP ++
Sbjct: 4340 -------HPGTPKPQGPTLEPPPGRVSPAAA 4363
Score = 33.5 bits (75), Expect = 1.1
Identities = 34/125 (27%), Positives = 50/125 (40%), Gaps = 16/125 (12%)
Query: 2 LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61
L P+P + P +P Q P ++ PPG P L G A S PG P SP
Sbjct: 860 LSPRPEKPPEEPGQCPAPEELPLFPPPG--EPSLSPLLGEPALS--EPGEP-PLSPLPEE 914
Query: 62 VAAAGSGLRRGAEGILAPQPPPPQ-----QHQERPGAAAIG------SARGQSTGKGPPQ 110
+ + SG + ++ P P PP P + +G A+G S + P
Sbjct: 915 LPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLA 974
Query: 111 SPVFE 115
+P+ E
Sbjct: 975 APILE 979
Score = 32.0 bits (71), Expect = 3.1
Identities = 38/130 (29%), Positives = 46/130 (35%), Gaps = 28/130 (21%)
Query: 1 MLKPQPLQQPSQPQQPPP-------TQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPA 53
+++PQP QPS Q PP QQ GG S G G ++S A P
Sbjct: 4077 LVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGS---HGQLGSGSSSEASSVPHL 4133
Query: 54 AASPCLGPVAAAGS-----------GLRRGAEGILAPQPPPP----QQHQERPGAA---A 95
A P + GS L R + PQPP P Q Q PG
Sbjct: 4134 LAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPT 4193
Query: 96 IGSARGQSTG 105
+G R Q G
Sbjct: 4194 VGQLRAQLQG 4203
Score = 31.6 bits (70), Expect = 4.1
Identities = 22/74 (29%), Positives = 27/74 (36%), Gaps = 1/74 (1%)
Query: 16 PPPTQQAVARRPPGGTSPPNGGLPG-PLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAE 74
PP V + P G +P P P A PP P +P P+ A S G
Sbjct: 2164 PPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQP 2223
Query: 75 GILAPQPPPPQQHQ 88
G PP +HQ
Sbjct: 2224 GEFHTTPPGTPRHQ 2237
Score = 31.2 bits (69), Expect = 5.3
Identities = 34/124 (27%), Positives = 44/124 (35%), Gaps = 23/124 (18%)
Query: 3 KPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPV 62
K Q QQ Q QQ Q A+ ++ G PG A P P P
Sbjct: 3733 KLQQQQQQQQQQQHLLGQVAIQQQQQQG--------PGVQTNQALGPKPQGLMPPS---- 3780
Query: 63 AAAGSGLRRGAEGILAPQ--PPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120
+G+L Q P PPQ Q G A + + Q G PQ P + +
Sbjct: 3781 ---------SHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQ 3831
Query: 121 SRML 124
SR+L
Sbjct: 3832 SRVL 3835
Score = 31.2 bits (69), Expect = 5.3
Identities = 31/112 (27%), Positives = 42/112 (37%), Gaps = 22/112 (19%)
Query: 834 IVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSP 893
I+S + P+ E PT SY ++ + L Q A P P APSP
Sbjct: 4875 ILSLLKQESPAPEPPT--------QHSYTYNVSNLDVRQLS-APPPEEPSPPPSPLAPSP 4925
Query: 894 VQHQAGQAPHLGSGQPQQNLYH-PGALTGTPPSLPPGPSAQSPQSSFPQPAA 944
+ P + L P PP P P A SP+S+ P+P A
Sbjct: 4926 ------------ASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRA 4965
Score = 30.4 bits (67), Expect = 9.1
Identities = 27/93 (29%), Positives = 40/93 (43%), Gaps = 11/93 (11%)
Query: 5 QPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAA 64
+PL++ P PPP + ++ PP +SP + PL+ P PA +P L P
Sbjct: 487 RPLEE--SPLSPPPEESPLS--PPPESSPFSPLEESPLSPPEESPPSPALETP-LSPPPE 541
Query: 65 AGSGLRRGAEGILAPQP------PPPQQHQERP 91
A E L+P P PPP+ + P
Sbjct: 542 ASPLSPPFEESPLSPPPEELPTSPPPEASRLSP 574
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
Length = 816
Score = 92.0 bits (227), Expect = 3e-18
Identities = 178/746 (23%), Positives = 251/746 (33%), Gaps = 141/746 (18%)
Query: 357 REGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGING-GPSRMSPKAQRP 415
R+ + G + PGL L PR P P + R + G P A+R
Sbjct: 5 RDKAKAGAAARTPAARAPGL--LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERA 62
Query: 416 LRGAKTLSSPSNRP-SGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTS 474
G + P + P +G T PPA GR K+ +P P+S+ P G+ P
Sbjct: 63 -GGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSS--PGRASGTTRP-- 117
Query: 475 SASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELAR-IAGKVPGL 533
G + +IS T + +T+ P R+ R +G PG
Sbjct: 118 ---------------GPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGT 162
Query: 534 QNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMG 593
+ R G + L P S P PP E P+ T+EP
Sbjct: 163 PSPA---MARRSRAAGTEVGLP---RPAPSARPRPPT---EGPRKSVSSASEHSTTEP-- 211
Query: 594 SPVSSKTESVSDKEDKPPLAPSGGTEGP-EQPPPPCPSQTGSPPVGLIKGEDKDEGPVAE 652
SP + + S +P + P P PS G+P + K +G +
Sbjct: 212 SPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKG--LQ 269
Query: 653 QVKKSTLNPNAKEFNPTK-PLLSVNKSTSTPTSPG-----PRTHSTPSIPVLTAGQS--G 704
++ + P K+ P PL S +T +P++P P + PS P Q+
Sbjct: 270 ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTS 329
Query: 705 LYSPQYI---SYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQP 761
L SP S++P + P P P ++ LPP ++ P
Sbjct: 330 LGSPTLQATHSFLPSPPLSPLATPPPQAPPALA----------------LPPLQAPPSPP 373
Query: 762 ASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSN 821
AS PP+ A + A + P++P P A P A P P P Q+
Sbjct: 374 AS-PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP 432
Query: 822 PRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTG 881
P + +S P PSA P PQA P A L +P P P
Sbjct: 433 PSLAAPPLQVPPSPPASPPMSPSA-TPPPQA-------PPPLAAPPLQLAKPPPQAPPAL 484
Query: 882 SQPQSQHAAPSPVQHQAGQAPH----------LGSGQPQQNLYHPGALTGTPPSLPPGPS 931
+ P Q A PSP GQAP L + PQ L PPS P P+
Sbjct: 485 ATPPLQ-ALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT 543
Query: 932 AQSPQ--------SSFPQPAAVYAIHHQQLP---------------HGFTNMAHVTQAHV 968
Q+P+ +S P A+ P G ++ A T +
Sbjct: 544 LQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEEL 603
Query: 969 -------QTGITAAPPP-------HPGA----PHPPQVM-------LLHPPQSHGGPPQG 1003
+ G A+PPP HP A P PP L PP + G G
Sbjct: 604 RGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADG 663
Query: 1004 AV-------PQSGVPALSASTPSPYP 1022
P+S PA A P P P
Sbjct: 664 LCTIYETEGPESATPAPGALDPGPSP 689
Score = 68.2 bits (165), Expect = 4e-11
Identities = 148/626 (23%), Positives = 204/626 (32%), Gaps = 146/626 (23%)
Query: 440 AVGRMYPPRSPKSAAPAPISASCPEPPIGSA---VPTSSASI---PVTSSVSDPGVGSIS 493
A R R+P P P + P PP+ A V ++ ++ P+ G +I
Sbjct: 12 AAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP 71
Query: 494 PASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFK 553
++P+ P RT P R + P +N
Sbjct: 72 ESAPRAG-------------PTRTSRPPASGR-GERAPPAKNTSPG-------------- 103
Query: 554 LQPSSSPENSLDPFPPRILKEEP---KGKEKEVDGLLTSEPMGSPVSS----KTESVSDK 606
P SSP + P L ++ +E G T P S +S+ T +
Sbjct: 104 --PVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPG 161
Query: 607 EDKPPLAPSGGTEGPEQP-PPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKE 665
P +A G E P P PS PP EGP +KS +A E
Sbjct: 162 TPSPAMARRSRAAGTEVGLPRPAPSARPRPPT---------EGP-----RKSV--SSASE 205
Query: 666 FNPTKPLLSVNKSTSTPTS---PGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPA 722
+ T+P + + S P R+ S+ + P+ + +SG P P
Sbjct: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG----------PSARGTPR 255
Query: 723 VQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGP----PL 778
A P P +G + PPQ + PP AA A GP PL
Sbjct: 256 APAHPSQPKP------------KGLQALRPPQVT--------PPRKDAAPALGPLSSSPL 295
Query: 779 VAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFA---PMLQSNPRMLTSGSHPQAIV 835
+P + P +P P + P A PSQ + P LQ+ L S P + +
Sbjct: 296 ATPSPSA---PPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSP--PLSPL 350
Query: 836 SSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQ 895
++ PQ P A P Q +P S P S A PSP Q
Sbjct: 351 ATPPPQAPPALALPPL----------------------QAPPSPPASPPLSPLATPSP-Q 387
Query: 896 HQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPH 955
A HL P +PP+ PP + +P S P A + P
Sbjct: 388 APNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP 447
Query: 956 GFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSA 1015
M+ +A PPP AP P L PP PP A P P L A
Sbjct: 448 ASPPMSP----------SATPPPQ--APPP----LAAPPLQLAKPPPQAPPALATPPLQA 491
Query: 1016 STPSPYPYIGHPQVQSHPSQQLPFHP 1041
P + G Q PS LP P
Sbjct: 492 LPSPPASFPG--QAPFSPSASLPMSP 515
Score = 63.2 bits (152), Expect = 1e-09
Identities = 132/518 (25%), Positives = 175/518 (33%), Gaps = 122/518 (23%)
Query: 585 GLLTSEPMGSP--------VSSKTESVSDKEDKPPLAPSGGTEG----PEQPPPPCPSQT 632
GLLT P GSP + + + + PLA G G PE P P++T
Sbjct: 23 GLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRT 82
Query: 633 GSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHST 692
PP +GE P AK +P P+ S +++ T T PGP
Sbjct: 83 SRPPASG-RGERA---------------PPAKNTSPG-PVSSPGRASGT-TRPGP----- 119
Query: 693 PSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLP 752
GQ GL IS + G A +AP+ G R G P
Sbjct: 120 -------LGQKGLR----ISAEETVARGKATEAPKRSALSA--------GARRDTSGPTP 160
Query: 753 PQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQP 812
S P M + + AAG + P S P P + P + ++ H ++P
Sbjct: 161 GTPS--------PAMARRSRAAGTEVGLPRPAPSARPRPPTEGP-RKSVSSASEHSTTEP 211
Query: 813 VFAPMLQSNP-----------RMLTSGSHPQAIVSSS------TPQYPS-AEQPTPQALY 854
+P + P R L+S + P + + S TP+ P+ QP P+ L
Sbjct: 212 --SPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQ 269
Query: 855 AT-VHQSYPHHATQLHA---------HQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHL 904
A Q P A P P+ P+ S P S PSP QA
Sbjct: 270 ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQAT-T 328
Query: 905 GSGQPQQNLYHP-------GALTGTPPSLPPG---PSAQSPQSS-FPQPAAVYAIHHQQL 953
G P H L PP PP P Q+P S P + A Q
Sbjct: 329 SLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQA 388
Query: 954 PHGFTNMAHVTQAHVQTGITAAPPPHP------GAPHPPQVMLLHPPQSHGGPPQGAVPQ 1007
P+ H+ QA +PPP P P P V P S P A P
Sbjct: 389 PNALA--VHLLQAPF------SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPL 440
Query: 1008 SGVPALSAS---TPSPYPYIGHPQVQSHPSQQLPFHPP 1042
P+ AS +PS P P + P QL PP
Sbjct: 441 QVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP 478
Score = 39.7 bits (91), Expect = 0.015
Identities = 33/123 (26%), Positives = 44/123 (35%), Gaps = 22/123 (17%)
Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTS------------PPNGGLPGPLATSAAPPGPPA 53
PLQ P P PP P + PP+ + P + A+PP P+
Sbjct: 365 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 424
Query: 54 AASPCLGPVAAAGSGLRRGAEGILAPQPP--PPQQHQERPGAAAIG--SARGQSTGKGPP 109
A P P + A L+ + P PP PP P A +A K PP
Sbjct: 425 ATPPSQAPPSLAAPPLQ------VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP 478
Query: 110 QSP 112
Q+P
Sbjct: 479 QAP 481
Score = 38.1 bits (87), Expect = 0.044
Identities = 35/110 (31%), Positives = 46/110 (41%), Gaps = 22/110 (20%)
Query: 10 PSQPQQPPPTQQAVARRPPGGTSPPNGGLP--GPLATS-AAPPGPPAAASPCLGPVAAAG 66
P+ P QP P + A RPP T P P GPL++S A P P A SP P
Sbjct: 257 PAHPSQPKP-KGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPP----- 310
Query: 67 SGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGK---GPPQSPV 113
+ + +P PP Q ++GS Q+T PP SP+
Sbjct: 311 -----SLQTLPSPPATPPSQ-----ATTSLGSPTLQATHSFLPSPPLSPL 350
Score = 37.0 bits (84), Expect = 0.097
Identities = 34/122 (27%), Positives = 48/122 (39%), Gaps = 15/122 (12%)
Query: 3 KPQPLQQPSQPQQPPPTQQAVAR---------RPPGGTSPPNGGLPGPLATSAAPPG-PP 52
KP+ LQ PQ PP + A P ++PP+ P L T +PP PP
Sbjct: 264 KPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPP 323
Query: 53 AAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARG-QSTGKGPPQS 111
+ A+ LG + + + PPPQ P A A+ + S PP S
Sbjct: 324 SQATTSLGSPTLQATHSFLPSPPLSPLATPPPQ----APPALALPPLQAPPSPPASPPLS 379
Query: 112 PV 113
P+
Sbjct: 380 PL 381
Score = 37.0 bits (84), Expect = 0.097
Identities = 39/122 (31%), Positives = 48/122 (39%), Gaps = 30/122 (24%)
Query: 13 PQQPP--PTQQAVARRPPGGTSPPNGGLPGP---LATSAAPPGPP--AAASPCLGPVAAA 65
P PP PT QA RRPP T P+ + GP LA + PP PP + +S GP A
Sbjct: 535 PPSPPASPTLQA-PRRPP--TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAG 591
Query: 66 GS-----------GLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVF 114
S G G EG A PPP A + + + +GP F
Sbjct: 592 HSSSATSTPEELRGYDSGPEGGAAASPPPD---------AELAACHPAAWSRGPAPPLAF 642
Query: 115 EG 116
G
Sbjct: 643 RG 644
Score = 33.9 bits (76), Expect = 0.82
Identities = 36/125 (28%), Positives = 43/125 (34%), Gaps = 27/125 (21%)
Query: 4 PQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLAT---------SAAPPGPPAA 54
P PL P PP Q PP +PP LP P A+ SA+ P P A
Sbjct: 463 PPPLAAPPLQLAKPPPQA-----PPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 517
Query: 55 ASPCLGPVAAAGSGLRRGAEGILAPQPP--PPQQHQER-----PGAAAIGSARGQSTGKG 107
P P A L+ + P PP P Q R P + G + G
Sbjct: 518 TPPPQAPPVLAAPLLQ------VPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG 571
Query: 108 PPQSP 112
PP P
Sbjct: 572 PPPPP 576
Score = 33.1 bits (74), Expect = 1.4
Identities = 39/143 (27%), Positives = 55/143 (38%), Gaps = 34/143 (23%)
Query: 1 MLKPQPLQQPSQPQQPPPTQQ----------AVARRP--------PGGTSPPNGGLPGPL 42
+L P+P P P+ PPP AV R+P G T P + GP
Sbjct: 24 LLTPRP---PGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPT 80
Query: 43 ATSAAPPG-----PPAAASPCLGPVAAAG--SGLRR----GAEG--ILAPQPPPPQQHQE 89
TS P P A + GPV++ G SG R G +G I A + + E
Sbjct: 81 RTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATE 140
Query: 90 RPGAAAIGSARGQSTGKGPPQSP 112
P +A+ + + T P +P
Sbjct: 141 APKRSALSAGARRDTSGPTPGTP 163
Score = 32.0 bits (71), Expect = 3.1
Identities = 30/100 (30%), Positives = 36/100 (36%), Gaps = 12/100 (12%)
Query: 10 PSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGL 69
P P PP Q PP PP L P + A+PP P A P A A L
Sbjct: 346 PLSPLATPPPQ-----APPALALPP---LQAPPSPPASPPLSPLATPSPQAPNALAVHLL 397
Query: 70 RRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPP 109
+ +P P PP Q P A+ S + PP
Sbjct: 398 ----QAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 433
Score = 31.6 bits (70), Expect = 4.1
Identities = 33/119 (27%), Positives = 43/119 (36%), Gaps = 21/119 (17%)
Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPG-P---PAAASPCLGP 61
P+Q P P PP + P +PP+ P PL +PP P P+A P P
Sbjct: 408 PVQAPFSPPASPPVSPSAT---PPSQAPPSLAAP-PLQVPPSPPASPPMSPSATPPPQAP 463
Query: 62 VAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGP-------PQSPV 113
A L+ LA PP P A+ S G+ P P SP+
Sbjct: 464 PPLAAPPLQ------LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL 516
Score = 31.6 bits (70), Expect = 4.1
Identities = 29/91 (31%), Positives = 34/91 (37%), Gaps = 13/91 (14%)
Query: 16 PPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEG 75
PPP + A P + P PLA AP G P P GP +A G EG
Sbjct: 618 PPPDAELAACHPAAWSRGP----APPLAFRGAP-GAPLPWPPATGPGSADGLCTIYETEG 672
Query: 76 ILAPQPPPPQQHQERPGAAAIGSARGQSTGK 106
P+ PGA G + G S GK
Sbjct: 673 --------PESATPAPGALDPGPSPGTSGGK 695
Score = 30.4 bits (67), Expect = 9.1
Identities = 31/126 (24%), Positives = 45/126 (35%), Gaps = 21/126 (16%)
Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGP--------PAAASP 57
P P++ +PP + + P TSP PG A+ PGP A +
Sbjct: 75 PRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPG-RASGTTRPGPLGQKGLRISAEETV 133
Query: 58 CLGPV------AAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIG------SARGQSTG 105
G +A +G RR G P P + R +G SAR +
Sbjct: 134 ARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPT 193
Query: 106 KGPPQS 111
+GP +S
Sbjct: 194 EGPRKS 199
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 855
Score = 86.7 bits (213), Expect = 1e-16
Identities = 183/757 (24%), Positives = 249/757 (32%), Gaps = 195/757 (25%)
Query: 357 REGP-RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRP 415
R GP R S + RP S R P N+SPGP S G G +R P Q+
Sbjct: 76 RAGPTRSAGTSSRNPASRPPASGRGERAPP-AKNTSPGPVSSP-GRASGTTRPGPLGQKG 133
Query: 416 LR---------GAKT-------LSSPSNRP-SGETSVPPPPAVGRMYPPRSPKSAAPAPI 458
LR G T LS+ + R SG T P PA+ R + P P
Sbjct: 134 LRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPA 193
Query: 459 SASCPEPPI-GSAVPTSSASIPVTSSVS-------DPGVGSISPASPKISLAPTDVKELS 510
++ P PP G SSAS T+ S G G PAS +S + T + +
Sbjct: 194 PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA 253
Query: 511 TKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPR 570
P AR + P ++ K L+ LR PP+
Sbjct: 254 RSGPS--------ARGTPRAPAHPSQPKPKGLQALR---------------------PPQ 284
Query: 571 ILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPS 630
+ P+ G L+S P+ +P +PS + Q PP P+
Sbjct: 285 VTP--PRKDAAPALGPLSSSPLATP-----------------SPSAALQS--QAPPTLPA 323
Query: 631 QTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTH 690
S + +A + + +P+A T P S P +P +
Sbjct: 324 TPHSSSLTC---------QLATPLPLAPPSPSAPPSLQTLP--------SPPATPPSQAT 366
Query: 691 STPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGS 750
++ P L A S L SP + P P P ++
Sbjct: 367 TSLGSPTLQATHSFLPSPP---------LSPLATPPPQAPPALA---------------- 401
Query: 751 LPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPS 810
LPP ++ PAS PP+ A + A + P++P P A P A P
Sbjct: 402 LPPLQAPPSPPAS-PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV 460
Query: 811 QPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHA 870
P P Q+ P + +S P PSA P PQA P A L
Sbjct: 461 SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSA-TPPPQA-------PPPLAAPPLQL 512
Query: 871 HQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPH----------LGSGQPQQNLYHPGALT 920
+P P P + P Q A PSP GQAP L + PQ L
Sbjct: 513 AKPPPQAPPALATPPLQ-ALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLL 571
Query: 921 GTPPSLPPGPSAQSPQ--------SSFPQPAAVYAIHHQQLP---------------HGF 957
PPS P P+ Q+P+ +S P A+ P G
Sbjct: 572 QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGH 631
Query: 958 TNMAHVTQAHV-------QTGITAAPPP-------HPGA----PHPPQVM-------LLH 992
++ A T + + G A+PPP HP A P PP L
Sbjct: 632 SSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPW 691
Query: 993 PPQSHGGPPQGAV-------PQSGVPALSASTPSPYP 1022
PP + G G P+S PA A P P P
Sbjct: 692 PPATGPGSADGLCTIYETEGPESATPAPGALDPGPSP 728
Score = 73.6 bits (179), Expect = 9e-13
Identities = 147/630 (23%), Positives = 206/630 (32%), Gaps = 115/630 (18%)
Query: 440 AVGRMYPPRSPKSAAPAPISASCPEPPIGSA---VPTSSASI---PVTSSVSDPGVGSIS 493
A R R+P P P + P PP+ A V ++ ++ P+ G +I
Sbjct: 12 AAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP 71
Query: 494 PASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFK 553
++P+ PT S++ P P R + P +N
Sbjct: 72 ESAPRAG--PTRSAGTSSRNPAS--RPPASGR-GERAPPAKNTSPG-------------- 112
Query: 554 LQPSSSPENSLDPFPPRILKEEP---KGKEKEVDGLLTSEPMGSPVSS----KTESVSDK 606
P SSP + P L ++ +E G T P S +S+ T +
Sbjct: 113 --PVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPG 170
Query: 607 EDKPPLAPSGGTEGPEQP-PPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKE 665
P +A G E P P PS PP EGP +KS +A E
Sbjct: 171 TPSPAMARRSRAAGTEVGLPRPAPSARPRPPT---------EGP-----RKSV--SSASE 214
Query: 666 FNPTKPLLSVNKSTSTPTS---PGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPA 722
+ T+P + + S P R+ S+ + P+ + +SG P P
Sbjct: 215 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG----------PSARGTPR 264
Query: 723 VQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGP----PL 778
A P P +G + PPQ + PP AA A GP PL
Sbjct: 265 APAHPSQPKP------------KGLQALRPPQVT--------PPRKDAAPALGPLSSSPL 304
Query: 779 VAATPYSSYIPYNPQQFPGQP-------AMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHP 831
+P ++ P P P + P+ P P P LQ+ P +
Sbjct: 305 ATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPS- 363
Query: 832 QAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAP 891
QA S +P + P + + P L Q +P S P S A P
Sbjct: 364 QATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATP 423
Query: 892 SPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQ 951
SP Q A HL P +PP+ PP + +P S P A +
Sbjct: 424 SP-QAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP 482
Query: 952 QLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVP 1011
P M+ +A PPP AP P L PP PP A P P
Sbjct: 483 PSPPASPPMSP----------SATPPPQ--APPP----LAAPPLQLAKPPPQAPPALATP 526
Query: 1012 ALSASTPSPYPYIGHPQVQSHPSQQLPFHP 1041
L A P + G Q PS LP P
Sbjct: 527 PLQALPSPPASFPG--QAPFSPSASLPMSP 554
Score = 62.4 bits (150), Expect = 2e-09
Identities = 129/533 (24%), Positives = 175/533 (32%), Gaps = 113/533 (21%)
Query: 585 GLLTSEPMGSP--------VSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPP 636
GLLT P GSP + + + + PLA G G P P +
Sbjct: 23 GLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRS 82
Query: 637 VGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIP 696
G P + + +++ P AK +P P+ S +++ T T PGP
Sbjct: 83 AGTSSRNPASRPPASGRGERA---PPAKNTSPG-PVSSPGRASGT-TRPGP--------- 128
Query: 697 VLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPV------SNSVPG-------QQGK 743
GQ GL IS + G A +AP+ S PG ++ +
Sbjct: 129 ---LGQKGLR----ISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSR 181
Query: 744 YRGAKGSLP--------------PQRS----DQHQPASAPPMMQAAAAAGPPLV------ 779
G + LP P++S +H P + +AG L
Sbjct: 182 AAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRS 241
Query: 780 ---AATPYSSYIPYNPQ-----QFPGQPAMMQPMAHYPSQP--VFAPMLQSNPRMLTSGS 829
+ATP SS P + P P+ +P +P V P + P + S
Sbjct: 242 LSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS 301
Query: 830 HPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHA 889
P A S S + + P L AT H S + P P P+ S P S
Sbjct: 302 SPLATPSPSA----ALQSQAPPTLPATPHSS----SLTCQLATPLPLAPPSPSAPPSLQT 353
Query: 890 APSPVQHQAGQAPHLGSGQPQQNLYHP-------GALTGTPPSLPPG---PSAQSPQSS- 938
PSP QA G P H L PP PP P Q+P S
Sbjct: 354 LPSPPATPPSQAT-TSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPP 412
Query: 939 FPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHP------GAPHPPQVMLLH 992
P + A Q P+ H+ QA +PPP P P P V
Sbjct: 413 ASPPLSPLATPSPQAPNALA--VHLLQAPF------SPPPSPPVQAPFSPPASPPVSPSA 464
Query: 993 PPQSHGGPPQGAVPQSGVPALSAS---TPSPYPYIGHPQVQSHPSQQLPFHPP 1042
P S P A P P+ AS +PS P P + P QL PP
Sbjct: 465 TPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP 517
Score = 39.7 bits (91), Expect = 0.015
Identities = 33/123 (26%), Positives = 44/123 (35%), Gaps = 22/123 (17%)
Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTS------------PPNGGLPGPLATSAAPPGPPA 53
PLQ P P PP P + PP+ + P + A+PP P+
Sbjct: 404 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 463
Query: 54 AASPCLGPVAAAGSGLRRGAEGILAPQPP--PPQQHQERPGAAAIG--SARGQSTGKGPP 109
A P P + A L+ + P PP PP P A +A K PP
Sbjct: 464 ATPPSQAPPSLAAPPLQ------VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP 517
Query: 110 QSP 112
Q+P
Sbjct: 518 QAP 520
Score = 37.0 bits (84), Expect = 0.097
Identities = 39/122 (31%), Positives = 48/122 (39%), Gaps = 30/122 (24%)
Query: 13 PQQPP--PTQQAVARRPPGGTSPPNGGLPGP---LATSAAPPGPP--AAASPCLGPVAAA 65
P PP PT QA RRPP T P+ + GP LA + PP PP + +S GP A
Sbjct: 574 PPSPPASPTLQA-PRRPP--TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAG 630
Query: 66 GS-----------GLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVF 114
S G G EG A PPP A + + + +GP F
Sbjct: 631 HSSSATSTPEELRGYDSGPEGGAAASPPPD---------AELAACHPAAWSRGPAPPLAF 681
Query: 115 EG 116
G
Sbjct: 682 RG 683
Score = 36.2 bits (82), Expect = 0.17
Identities = 35/124 (28%), Positives = 47/124 (37%), Gaps = 20/124 (16%)
Query: 3 KPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAA-------- 54
KP+ LQ PQ PP + A P +SP P S APP PA
Sbjct: 273 KPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTC 332
Query: 55 --ASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGK---GPP 109
A+P P+A + + +P PP Q ++GS Q+T PP
Sbjct: 333 QLATPL--PLAPPSPSAPPSLQTLPSPPATPPSQ-----ATTSLGSPTLQATHSFLPSPP 385
Query: 110 QSPV 113
SP+
Sbjct: 386 LSPL 389
Score = 33.9 bits (76), Expect = 0.82
Identities = 36/125 (28%), Positives = 43/125 (34%), Gaps = 27/125 (21%)
Query: 4 PQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLAT---------SAAPPGPPAA 54
P PL P PP Q PP +PP LP P A+ SA+ P P A
Sbjct: 502 PPPLAAPPLQLAKPPPQA-----PPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 556
Query: 55 ASPCLGPVAAAGSGLRRGAEGILAPQPP--PPQQHQER-----PGAAAIGSARGQSTGKG 107
P P A L+ + P PP P Q R P + G + G
Sbjct: 557 TPPPQAPPVLAAPLLQ------VPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG 610
Query: 108 PPQSP 112
PP P
Sbjct: 611 PPPPP 615
Score = 32.0 bits (71), Expect = 3.1
Identities = 30/100 (30%), Positives = 36/100 (36%), Gaps = 12/100 (12%)
Query: 10 PSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGL 69
P P PP Q PP PP L P + A+PP P A P A A L
Sbjct: 385 PLSPLATPPPQ-----APPALALPP---LQAPPSPPASPPLSPLATPSPQAPNALAVHLL 436
Query: 70 RRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPP 109
+ +P P PP Q P A+ S + PP
Sbjct: 437 ----QAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 472
Score = 31.6 bits (70), Expect = 4.1
Identities = 33/119 (27%), Positives = 43/119 (36%), Gaps = 21/119 (17%)
Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPG-P---PAAASPCLGP 61
P+Q P P PP + P +PP+ P PL +PP P P+A P P
Sbjct: 447 PVQAPFSPPASPPVSPSAT---PPSQAPPSLAAP-PLQVPPSPPASPPMSPSATPPPQAP 502
Query: 62 VAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGP-------PQSPV 113
A L+ LA PP P A+ S G+ P P SP+
Sbjct: 503 PPLAAPPLQ------LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL 555
Score = 31.6 bits (70), Expect = 4.1
Identities = 29/91 (31%), Positives = 34/91 (37%), Gaps = 13/91 (14%)
Query: 16 PPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEG 75
PPP + A P + P PLA AP G P P GP +A G EG
Sbjct: 657 PPPDAELAACHPAAWSRGP----APPLAFRGAP-GAPLPWPPATGPGSADGLCTIYETEG 711
Query: 76 ILAPQPPPPQQHQERPGAAAIGSARGQSTGK 106
P+ PGA G + G S GK
Sbjct: 712 --------PESATPAPGALDPGPSPGTSGGK 734
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 84.7 bits (208), Expect = 4e-16
Identities = 142/534 (26%), Positives = 191/534 (35%), Gaps = 87/534 (16%)
Query: 561 ENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTES-VSDKEDKPPLAPSGGTE 619
E +DP PP + K ++E DGL M + S + S + K P +P G T
Sbjct: 546 EKPVDP-PPFMFKPV----KEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTS 600
Query: 620 GPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKST 679
+ S SP D AE VKKS + +P K +
Sbjct: 601 PINEDIRS--SGRNSPSAASTSSNDSK----AETVKKSAKKVKEEASSPLKSNKRQREKV 654
Query: 680 STPTSPGPRTHST---------PSIPVLTAGQS---------GLYSPQYISYIPQIHMGP 721
++ T RT S P+ P G+S G P+ I + P
Sbjct: 655 ASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNR-STSP 713
Query: 722 AVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAA 781
++ +PQ +S QQ + +L P+SAPP GP
Sbjct: 714 SIPSPQDNESDSDSSA--QQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGP----- 766
Query: 782 TPYSSYIPYNPQQFP-GQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840
TP ++ +P PQ P A QP A P+ PV +Q P + HPQ S P
Sbjct: 767 TPSATAVP--PQGSPTASQAPNQPQA--PTAPVPHTHIQQAPAL-----HPQRPPSPHPP 817
Query: 841 QYPSAEQPTPQALYATVHQSYPHHATQ-LHAHQPQPATTPTGSQPQSQHAAPS-----PV 894
+PS P + S P HA LH P P + P QH P P
Sbjct: 818 PHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGP-PGPHSLQAGPLLQHPGPPQPFGLPP 876
Query: 895 QHQAGQAPHLGSGQ----PQQNLYHPGALTGT----PPS---LPPGPSAQ--------SP 935
Q GQAP LG+ P +L P + + PP LPP P A +P
Sbjct: 877 QASQGQAP-LGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTP 935
Query: 936 QSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQ 995
P P A H P F+ A++ +++ HP + HPP + L+ PQ
Sbjct: 936 IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM--PQ 993
Query: 996 SHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQVQSH------PSQQLPFHPPG 1043
S P A P P L+ S P P HP H P Q PF P G
Sbjct: 994 SQPLPSSPAQP----PGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGG 1043
Score = 73.2 bits (178), Expect = 1e-12
Identities = 133/610 (21%), Positives = 211/610 (34%), Gaps = 109/610 (17%)
Query: 430 SGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVS--DP 487
SG+ S+ + G M RS + PA S PI + +S + P +S S D
Sbjct: 567 SGKHSMRTRRSRGSMSTLRSGRKKQPA--SPDGRTSPINEDIRSSGRNSPSAASTSSNDS 624
Query: 488 GVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRK 547
++ ++ K+ + + + ++ + E A + K+ + +E+ +
Sbjct: 625 KAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEAD--------RTSSKKTKTQEISR 676
Query: 548 FGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVD--GLLTSEPMGSPVSSKTESVSD 605
P+S E + R + +E K++D TS + SP ++++S S
Sbjct: 677 --------PNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSS 728
Query: 606 KEDK-----PPL--APSGGTEGPEQPPP---------PCPSQTGSPPVGLIKGEDKDEGP 649
+ + PP AP+G T P PP P PS T PP G P
Sbjct: 729 AQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQP 788
Query: 650 VAEQV--------KKSTLNPNAKEF-------NPTKPLLSVNKSTSTPTSPGPRTHSTPS 694
A + L+P +P PL + S P++P +H+ P
Sbjct: 789 QAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAP---SHAQP- 844
Query: 695 IPVLTAGQSGLYS------------PQYISYIPQIHMGPA---VQAPQMYPYPVSNSVPG 739
P+ G G +S PQ PQ G A YP+ S +P
Sbjct: 845 -PLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPH-TSLQLPA 902
Query: 740 QQGKYRGAKG-------------------------SLPPQRSDQHQPASAPPMMQAAAAA 774
Q + + LP ++ +H P + P + A
Sbjct: 903 SQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNAN 962
Query: 775 GPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAH-YPSQPVFAPML-QSNPRMLTSGSHPQ 832
PP A P SS ++P P + P + PS P P L QS SHP
Sbjct: 963 LPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPP 1022
Query: 833 AIVSSSTPQYPSAEQP-TPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAP 891
+ PQ P A+ P P + P +T PA T +QP AA
Sbjct: 1023 TGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTP-------PAGPGTSAQPPCSGAAA 1075
Query: 892 SPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQ 951
S G + L + Q ++ +PP P PS + P A+ A ++
Sbjct: 1076 SGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYK 1135
Query: 952 QLPHGFTNMA 961
L G+ + A
Sbjct: 1136 HLDRGYNSCA 1145
Score = 47.0 bits (110), Expect = 9e-05
Identities = 135/639 (21%), Positives = 209/639 (32%), Gaps = 114/639 (17%)
Query: 374 PGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSP--SNRPSG 431
P L L HH ++ P P PS SP L ++ L P S+ P+G
Sbjct: 967 PALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPS--SPAQPPGLTQSQNLPPPPASHPPTG 1024
Query: 432 ETSVPP-PPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPG-- 488
V P PP + P P P P S PP G P +SA P + + + G
Sbjct: 1025 LHQVAPQPPFAQHPFVPGGPPPITP-PTCPSTSTPPAG---PGTSAQPPCSGAAASGGSI 1080
Query: 489 VGSISPASPKISLAPTDVKELSTKE----PGRTLEPQ-----------ELARIAGKVPGL 533
G S P + + + + E P R+ P+ + AR +
Sbjct: 1081 AGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRG 1140
Query: 534 QNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMG 593
N R L + G++ + + E + + +E + KEKE + E
Sbjct: 1141 YNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKERERERERER 1200
Query: 594 SPVSSKTESVSDKEDK--PPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVA 651
+ S S E + P G P PPP P +G
Sbjct: 1201 EAERAAKASSSAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIG------------- 1247
Query: 652 EQVKKSTLNPNAKEFNPTKPLLSVNKSTSTP--TSPGPRTHS-----TPSIPVLTAGQSG 704
P P L + P SP R H P+ P+L G
Sbjct: 1248 ----------------PDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPG 1291
Query: 705 LYSPQYISYIPQIHMGPAVQAPQMYPYPV-SNSVPGQQGKYRGAKG-SLPPQRSDQHQPA 762
LY+ + P ++ ++ + + ++ + R G + P D PA
Sbjct: 1292 LYN-----------VDPTIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPA 1340
Query: 763 SAPP--MMQAAAAAGPPLVAATPYSSYIP-YNP---QQFPGQPAMMQPMAHYPSQPVFAP 816
+ P + +A PP P++S+ P NP ++ ++P YP +
Sbjct: 1341 ANPMEHFARHSALTIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAER 1400
Query: 817 MLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQP- 875
+ LTS + + + TP H + H + LH HQ P
Sbjct: 1401 IHAERMASLTSDPLARLQMFNVTPH----------------HHQHSHIHSHLHLHQQDPL 1444
Query: 876 ---ATTPTGSQPQSQHAAP--SPVQHQAGQAPHLGSGQP---QQNLYHPGALTGTPPSL- 926
+ P A P + + G P+ GQP + L HP T P L
Sbjct: 1445 HQGSAGPVHPLVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLP 1504
Query: 927 ----PPGPSAQSPQSSFPQPAAVYAI-HHQQLPHGFTNM 960
PP +A Q+ Q A + + QQ HG +M
Sbjct: 1505 GAIPPPMSAAHQLQAMHAQSAELQRLAMEQQWLHGHPHM 1543
Score = 45.1 bits (105), Expect = 4e-04
Identities = 39/134 (29%), Positives = 51/134 (38%), Gaps = 32/134 (23%)
Query: 2 LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNG-----------------GLPGPL-- 42
L PQ PS P QPP Q+ PP + PP G G P P+
Sbjct: 990 LMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITP 1049
Query: 43 ----ATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGS 98
+TS P GP +A P AA+G + G+ P P Q +E A+
Sbjct: 1050 PTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSS-----CPLPTVQIKEE----ALDD 1100
Query: 99 ARGQSTGKGPPQSP 112
A + PP+SP
Sbjct: 1101 AEEPESPPPPPRSP 1114
Score = 41.2 bits (95), Expect = 0.005
Identities = 92/374 (24%), Positives = 125/374 (33%), Gaps = 82/374 (21%)
Query: 371 GGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPS 430
G P SS PP P +PGP A + P +G+ T S N+P
Sbjct: 746 GVTPAPSSAPPGTPQL---PTPGPTPSATAV-------------PPQGSPTASQAPNQPQ 789
Query: 431 GETSVPPPPAVGR---MYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDP 487
T+ P + + ++P R P +P P P PP+ T SA P S + P
Sbjct: 790 APTAPVPHTHIQQAPALHPQRPP---SPHPPPHPSPHPPLQPL--TGSAGQPSAPSHAQP 844
Query: 488 GVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRK 547
+ P P A ++ +P L PQ G+ P + + L+
Sbjct: 845 PLHGQGPPGPHSLQAGPLLQHPGPPQP-FGLPPQ---ASQGQAPLGTSPAAAYPHTSLQL 900
Query: 548 FGAQFKLQPSSSP-ENSLDPFP-------------------PRILKEEPK---GKEKEVD 584
+Q LQ P E L P P P+ K P ++
Sbjct: 901 PASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMN 960
Query: 585 GLLTSEPMGSPVSSKTESVSDKEDKPPL--------------APSGGTEGPEQPPPPCPS 630
L P P+SS + PPL P G T+ PPPP
Sbjct: 961 ANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPP--- 1017
Query: 631 QTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTH 690
PP GL + + P A+ P PT P STSTP + GP T
Sbjct: 1018 -ASHPPTGL--HQVAPQPPFAQHPFVPGGPPPITP--PTCP------STSTPPA-GPGTS 1065
Query: 691 STPSIPVLTAGQSG 704
+ P P A SG
Sbjct: 1066 AQP--PCSGAAASG 1077
Score = 38.9 bits (89), Expect = 0.026
Identities = 38/118 (32%), Positives = 46/118 (38%), Gaps = 10/118 (8%)
Query: 4 PQPLQQPSQPQQP----PPT--QQAVA---RRPPGGTSPPNGGLPGPLATSAAPPGPPAA 54
P Q P+QPQ P P T QQA A +RPP PP+ PL G P+A
Sbjct: 779 PTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSA 838
Query: 55 ASPCLGPVAAAG-SGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS 111
S P+ G G G L P PPQ P A+ + G S P +
Sbjct: 839 PSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHT 896
Score = 37.0 bits (84), Expect = 0.097
Identities = 32/110 (29%), Positives = 41/110 (37%), Gaps = 6/110 (5%)
Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAA 65
P Q ++ QQ + + P P G P P S+APPG P +P P A A
Sbjct: 716 PSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAP---SSAPPGTPQLPTPGPTPSATA 772
Query: 66 --GSGLRRGAEGILAPQ-PPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112
G ++ PQ P P H A A+ R S P SP
Sbjct: 773 VPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSP 822
Score = 36.6 bits (83), Expect = 0.13
Identities = 30/111 (27%), Positives = 38/111 (34%), Gaps = 7/111 (6%)
Query: 9 QPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSG 68
QP Q P A + PPG P G P P AT+ P G P A+ P A
Sbjct: 737 QPPALQAPTGVTPAPSSAPPGTPQLPTPG-PTPSATAVPPQGSPTASQAPNQPQAPTAPV 795
Query: 69 LRRGAEGILA------PQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPV 113
+ A P P PP P + + GQ + Q P+
Sbjct: 796 PHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPL 846
Score = 32.3 bits (72), Expect = 2.4
Identities = 33/111 (29%), Positives = 42/111 (37%), Gaps = 15/111 (13%)
Query: 2 LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61
L P PL P + PP T P PP+ P P + +A P PPA L P
Sbjct: 918 LPPAPLAMP-HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPA-----LKP 971
Query: 62 VAAAGSGLRRGAEGILAPQPPPPQ---QHQERPGAAAIGSARGQSTGKGPP 109
+++ + A PPP Q Q Q P + A QS PP
Sbjct: 972 LSSLSTHHPPSA------HPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPP 1016
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 84.7 bits (208), Expect = 4e-16
Identities = 142/534 (26%), Positives = 191/534 (35%), Gaps = 87/534 (16%)
Query: 561 ENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTES-VSDKEDKPPLAPSGGTE 619
E +DP PP + K ++E DGL M + S + S + K P +P G T
Sbjct: 546 EKPVDP-PPFMFKPV----KEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTS 600
Query: 620 GPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKST 679
+ S SP D AE VKKS + +P K +
Sbjct: 601 PINEDIRS--SGRNSPSAASTSSNDSK----AETVKKSAKKVKEEASSPLKSNKRQREKV 654
Query: 680 STPTSPGPRTHST---------PSIPVLTAGQS---------GLYSPQYISYIPQIHMGP 721
++ T RT S P+ P G+S G P+ I + P
Sbjct: 655 ASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNR-STSP 713
Query: 722 AVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAA 781
++ +PQ +S QQ + +L P+SAPP GP
Sbjct: 714 SIPSPQDNESDSDSSA--QQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGP----- 766
Query: 782 TPYSSYIPYNPQQFP-GQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840
TP ++ +P PQ P A QP A P+ PV +Q P + HPQ S P
Sbjct: 767 TPSATAVP--PQGSPTASQAPNQPQA--PTAPVPHTHIQQAPAL-----HPQRPPSPHPP 817
Query: 841 QYPSAEQPTPQALYATVHQSYPHHATQ-LHAHQPQPATTPTGSQPQSQHAAPS-----PV 894
+PS P + S P HA LH P P + P QH P P
Sbjct: 818 PHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGP-PGPHSLQAGPLLQHPGPPQPFGLPP 876
Query: 895 QHQAGQAPHLGSGQ----PQQNLYHPGALTGT----PPS---LPPGPSAQ--------SP 935
Q GQAP LG+ P +L P + + PP LPP P A +P
Sbjct: 877 QASQGQAP-LGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTP 935
Query: 936 QSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQ 995
P P A H P F+ A++ +++ HP + HPP + L+ PQ
Sbjct: 936 IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM--PQ 993
Query: 996 SHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQVQSH------PSQQLPFHPPG 1043
S P A P P L+ S P P HP H P Q PF P G
Sbjct: 994 SQPLPSSPAQP----PGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGG 1043
Score = 73.2 bits (178), Expect = 1e-12
Identities = 133/610 (21%), Positives = 211/610 (34%), Gaps = 109/610 (17%)
Query: 430 SGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVS--DP 487
SG+ S+ + G M RS + PA S PI + +S + P +S S D
Sbjct: 567 SGKHSMRTRRSRGSMSTLRSGRKKQPA--SPDGRTSPINEDIRSSGRNSPSAASTSSNDS 624
Query: 488 GVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRK 547
++ ++ K+ + + + ++ + E A + K+ + +E+ +
Sbjct: 625 KAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEAD--------RTSSKKTKTQEISR 676
Query: 548 FGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVD--GLLTSEPMGSPVSSKTESVSD 605
P+S E + R + +E K++D TS + SP ++++S S
Sbjct: 677 --------PNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSS 728
Query: 606 KEDK-----PPL--APSGGTEGPEQPPP---------PCPSQTGSPPVGLIKGEDKDEGP 649
+ + PP AP+G T P PP P PS T PP G P
Sbjct: 729 AQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQP 788
Query: 650 VAEQV--------KKSTLNPNAKEF-------NPTKPLLSVNKSTSTPTSPGPRTHSTPS 694
A + L+P +P PL + S P++P +H+ P
Sbjct: 789 QAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAP---SHAQP- 844
Query: 695 IPVLTAGQSGLYS------------PQYISYIPQIHMGPA---VQAPQMYPYPVSNSVPG 739
P+ G G +S PQ PQ G A YP+ S +P
Sbjct: 845 -PLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPH-TSLQLPA 902
Query: 740 QQGKYRGAKG-------------------------SLPPQRSDQHQPASAPPMMQAAAAA 774
Q + + LP ++ +H P + P + A
Sbjct: 903 SQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNAN 962
Query: 775 GPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAH-YPSQPVFAPML-QSNPRMLTSGSHPQ 832
PP A P SS ++P P + P + PS P P L QS SHP
Sbjct: 963 LPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPP 1022
Query: 833 AIVSSSTPQYPSAEQP-TPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAP 891
+ PQ P A+ P P + P +T PA T +QP AA
Sbjct: 1023 TGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTP-------PAGPGTSAQPPCSGAAA 1075
Query: 892 SPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQ 951
S G + L + Q ++ +PP P PS + P A+ A ++
Sbjct: 1076 SGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYK 1135
Query: 952 QLPHGFTNMA 961
L G+ + A
Sbjct: 1136 HLDRGYNSCA 1145
Score = 47.0 bits (110), Expect = 9e-05
Identities = 135/639 (21%), Positives = 209/639 (32%), Gaps = 114/639 (17%)
Query: 374 PGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSP--SNRPSG 431
P L L HH ++ P P PS SP L ++ L P S+ P+G
Sbjct: 967 PALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPS--SPAQPPGLTQSQNLPPPPASHPPTG 1024
Query: 432 ETSVPP-PPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPG-- 488
V P PP + P P P P S PP G P +SA P + + + G
Sbjct: 1025 LHQVAPQPPFAQHPFVPGGPPPITP-PTCPSTSTPPAG---PGTSAQPPCSGAAASGGSI 1080
Query: 489 VGSISPASPKISLAPTDVKELSTKE----PGRTLEPQ-----------ELARIAGKVPGL 533
G S P + + + + E P R+ P+ + AR +
Sbjct: 1081 AGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRG 1140
Query: 534 QNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMG 593
N R L + G++ + + E + + +E + KEKE + E
Sbjct: 1141 YNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKERERERERER 1200
Query: 594 SPVSSKTESVSDKEDK--PPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVA 651
+ S S E + P G P PPP P +G
Sbjct: 1201 EAERAAKASSSAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIG------------- 1247
Query: 652 EQVKKSTLNPNAKEFNPTKPLLSVNKSTSTP--TSPGPRTHS-----TPSIPVLTAGQSG 704
P P L + P SP R H P+ P+L G
Sbjct: 1248 ----------------PDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPG 1291
Query: 705 LYSPQYISYIPQIHMGPAVQAPQMYPYPV-SNSVPGQQGKYRGAKG-SLPPQRSDQHQPA 762
LY+ + P ++ ++ + + ++ + R G + P D PA
Sbjct: 1292 LYN-----------VDPTIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPA 1340
Query: 763 SAPP--MMQAAAAAGPPLVAATPYSSYIP-YNP---QQFPGQPAMMQPMAHYPSQPVFAP 816
+ P + +A PP P++S+ P NP ++ ++P YP +
Sbjct: 1341 ANPMEHFARHSALTIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAER 1400
Query: 817 MLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQP- 875
+ LTS + + + TP H + H + LH HQ P
Sbjct: 1401 IHAERMASLTSDPLARLQMFNVTPH----------------HHQHSHIHSHLHLHQQDPL 1444
Query: 876 ---ATTPTGSQPQSQHAAP--SPVQHQAGQAPHLGSGQP---QQNLYHPGALTGTPPSL- 926
+ P A P + + G P+ GQP + L HP T P L
Sbjct: 1445 HQGSAGPVHPLVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLP 1504
Query: 927 ----PPGPSAQSPQSSFPQPAAVYAI-HHQQLPHGFTNM 960
PP +A Q+ Q A + + QQ HG +M
Sbjct: 1505 GAIPPPMSAAHQLQAMHAQSAELQRLAMEQQWLHGHPHM 1543
Score = 45.1 bits (105), Expect = 4e-04
Identities = 39/134 (29%), Positives = 51/134 (38%), Gaps = 32/134 (23%)
Query: 2 LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNG-----------------GLPGPL-- 42
L PQ PS P QPP Q+ PP + PP G G P P+
Sbjct: 990 LMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITP 1049
Query: 43 ----ATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGS 98
+TS P GP +A P AA+G + G+ P P Q +E A+
Sbjct: 1050 PTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSS-----CPLPTVQIKEE----ALDD 1100
Query: 99 ARGQSTGKGPPQSP 112
A + PP+SP
Sbjct: 1101 AEEPESPPPPPRSP 1114
Score = 41.2 bits (95), Expect = 0.005
Identities = 92/374 (24%), Positives = 125/374 (33%), Gaps = 82/374 (21%)
Query: 371 GGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPS 430
G P SS PP P +PGP A + P +G+ T S N+P
Sbjct: 746 GVTPAPSSAPPGTPQL---PTPGPTPSATAV-------------PPQGSPTASQAPNQPQ 789
Query: 431 GETSVPPPPAVGR---MYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDP 487
T+ P + + ++P R P +P P P PP+ T SA P S + P
Sbjct: 790 APTAPVPHTHIQQAPALHPQRPP---SPHPPPHPSPHPPLQPL--TGSAGQPSAPSHAQP 844
Query: 488 GVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRK 547
+ P P A ++ +P L PQ G+ P + + L+
Sbjct: 845 PLHGQGPPGPHSLQAGPLLQHPGPPQP-FGLPPQ---ASQGQAPLGTSPAAAYPHTSLQL 900
Query: 548 FGAQFKLQPSSSP-ENSLDPFP-------------------PRILKEEPK---GKEKEVD 584
+Q LQ P E L P P P+ K P ++
Sbjct: 901 PASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMN 960
Query: 585 GLLTSEPMGSPVSSKTESVSDKEDKPPL--------------APSGGTEGPEQPPPPCPS 630
L P P+SS + PPL P G T+ PPPP
Sbjct: 961 ANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPP--- 1017
Query: 631 QTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTH 690
PP GL + + P A+ P PT P STSTP + GP T
Sbjct: 1018 -ASHPPTGL--HQVAPQPPFAQHPFVPGGPPPITP--PTCP------STSTPPA-GPGTS 1065
Query: 691 STPSIPVLTAGQSG 704
+ P P A SG
Sbjct: 1066 AQP--PCSGAAASG 1077
Score = 38.9 bits (89), Expect = 0.026
Identities = 38/118 (32%), Positives = 46/118 (38%), Gaps = 10/118 (8%)
Query: 4 PQPLQQPSQPQQP----PPT--QQAVA---RRPPGGTSPPNGGLPGPLATSAAPPGPPAA 54
P Q P+QPQ P P T QQA A +RPP PP+ PL G P+A
Sbjct: 779 PTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSA 838
Query: 55 ASPCLGPVAAAG-SGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS 111
S P+ G G G L P PPQ P A+ + G S P +
Sbjct: 839 PSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHT 896
Score = 37.0 bits (84), Expect = 0.097
Identities = 32/110 (29%), Positives = 41/110 (37%), Gaps = 6/110 (5%)
Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAA 65
P Q ++ QQ + + P P G P P S+APPG P +P P A A
Sbjct: 716 PSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAP---SSAPPGTPQLPTPGPTPSATA 772
Query: 66 --GSGLRRGAEGILAPQ-PPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112
G ++ PQ P P H A A+ R S P SP
Sbjct: 773 VPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSP 822
Score = 36.6 bits (83), Expect = 0.13
Identities = 30/111 (27%), Positives = 38/111 (34%), Gaps = 7/111 (6%)
Query: 9 QPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSG 68
QP Q P A + PPG P G P P AT+ P G P A+ P A
Sbjct: 737 QPPALQAPTGVTPAPSSAPPGTPQLPTPG-PTPSATAVPPQGSPTASQAPNQPQAPTAPV 795
Query: 69 LRRGAEGILA------PQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPV 113
+ A P P PP P + + GQ + Q P+
Sbjct: 796 PHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPL 846
Score = 32.3 bits (72), Expect = 2.4
Identities = 33/111 (29%), Positives = 42/111 (37%), Gaps = 15/111 (13%)
Query: 2 LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61
L P PL P + PP T P PP+ P P + +A P PPA L P
Sbjct: 918 LPPAPLAMP-HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPA-----LKP 971
Query: 62 VAAAGSGLRRGAEGILAPQPPPPQ---QHQERPGAAAIGSARGQSTGKGPP 109
+++ + A PPP Q Q Q P + A QS PP
Sbjct: 972 LSSLSTHHPPSA------HPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPP 1016
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 83.2 bits (204), Expect = 1e-15
Identities = 137/518 (26%), Positives = 184/518 (35%), Gaps = 82/518 (15%)
Query: 577 KGKEKEVDGLLTSEPMGSPVSSKTES-VSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSP 635
K ++E DGL M + S + S + K P +P G T + S SP
Sbjct: 3 KPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRS--SGRNSP 60
Query: 636 PVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHST--- 692
D AE VKKS + +P K + ++ T RT S
Sbjct: 61 SAASTSSNDSK----AETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTK 116
Query: 693 ------PSIPVLTAGQS---------GLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSV 737
P+ P G+S G P+ I + P++ +PQ +S
Sbjct: 117 TQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNR-STSPSIPSPQDNESDSDSSA 175
Query: 738 PGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFP- 796
QQ + +L P+SAPP GP TP ++ +P PQ P
Sbjct: 176 --QQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGP-----TPSATAVP--PQGSPT 226
Query: 797 GQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYAT 856
A QP A P+ PV +Q P + HPQ S P +PS P +
Sbjct: 227 ASQAPNQPQA--PTAPVPHTHIQQAPAL-----HPQRPPSPHPPPHPSPHPPLQPLTGSA 279
Query: 857 VHQSYPHHATQ-LHAHQPQPATTPTGSQPQSQHAAPS-----PVQHQAGQAPHLGSGQ-- 908
S P HA LH P P + P QH P P Q GQAP LG+
Sbjct: 280 GQPSAPSHAQPPLHGQGP-PGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAP-LGTSPAA 337
Query: 909 --PQQNLYHPGALTGT----PPS---LPPGPSAQ--------SPQSSFPQPAAVYAIHHQ 951
P +L P + + PP LPP P A +P P P A H
Sbjct: 338 AYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHL 397
Query: 952 QLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVP 1011
P F+ A++ +++ HP + HPP + L+ PQS P A P P
Sbjct: 398 SGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM--PQSQPLPSSPAQP----P 451
Query: 1012 ALSASTPSPYPYIGHPQVQSH------PSQQLPFHPPG 1043
L+ S P P HP H P Q PF P G
Sbjct: 452 GLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGG 489
Score = 73.2 bits (178), Expect = 1e-12
Identities = 133/610 (21%), Positives = 211/610 (34%), Gaps = 109/610 (17%)
Query: 430 SGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVS--DP 487
SG+ S+ + G M RS + PA S PI + +S + P +S S D
Sbjct: 13 SGKHSMRTRRSRGSMSTLRSGRKKQPA--SPDGRTSPINEDIRSSGRNSPSAASTSSNDS 70
Query: 488 GVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRK 547
++ ++ K+ + + + ++ + E A + K+ + +E+ +
Sbjct: 71 KAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEAD--------RTSSKKTKTQEISR 122
Query: 548 FGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVD--GLLTSEPMGSPVSSKTESVSD 605
P+S E + R + +E K++D TS + SP ++++S S
Sbjct: 123 --------PNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSS 174
Query: 606 KEDK-----PPL--APSGGTEGPEQPPP---------PCPSQTGSPPVGLIKGEDKDEGP 649
+ + PP AP+G T P PP P PS T PP G P
Sbjct: 175 AQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQP 234
Query: 650 VAEQV--------KKSTLNPNAKEF-------NPTKPLLSVNKSTSTPTSPGPRTHSTPS 694
A + L+P +P PL + S P++P +H+ P
Sbjct: 235 QAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAP---SHAQP- 290
Query: 695 IPVLTAGQSGLYS------------PQYISYIPQIHMGPA---VQAPQMYPYPVSNSVPG 739
P+ G G +S PQ PQ G A YP+ S +P
Sbjct: 291 -PLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPH-TSLQLPA 348
Query: 740 QQGKYRGAKG-------------------------SLPPQRSDQHQPASAPPMMQAAAAA 774
Q + + LP ++ +H P + P + A
Sbjct: 349 SQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNAN 408
Query: 775 GPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAH-YPSQPVFAPML-QSNPRMLTSGSHPQ 832
PP A P SS ++P P + P + PS P P L QS SHP
Sbjct: 409 LPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPP 468
Query: 833 AIVSSSTPQYPSAEQP-TPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAP 891
+ PQ P A+ P P + P +T PA T +QP AA
Sbjct: 469 TGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTP-------PAGPGTSAQPPCSGAAA 521
Query: 892 SPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQ 951
S G + L + Q ++ +PP P PS + P A+ A ++
Sbjct: 522 SGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYK 581
Query: 952 QLPHGFTNMA 961
L G+ + A
Sbjct: 582 HLDRGYNSCA 591
Score = 47.0 bits (110), Expect = 9e-05
Identities = 135/639 (21%), Positives = 209/639 (32%), Gaps = 114/639 (17%)
Query: 374 PGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSP--SNRPSG 431
P L L HH ++ P P PS SP L ++ L P S+ P+G
Sbjct: 413 PALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPS--SPAQPPGLTQSQNLPPPPASHPPTG 470
Query: 432 ETSVPP-PPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPG-- 488
V P PP + P P P P S PP G P +SA P + + + G
Sbjct: 471 LHQVAPQPPFAQHPFVPGGPPPITP-PTCPSTSTPPAG---PGTSAQPPCSGAAASGGSI 526
Query: 489 VGSISPASPKISLAPTDVKELSTKE----PGRTLEPQ-----------ELARIAGKVPGL 533
G S P + + + + E P R+ P+ + AR +
Sbjct: 527 AGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRG 586
Query: 534 QNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMG 593
N R L + G++ + + E + + +E + KEKE + E
Sbjct: 587 YNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKERERERERER 646
Query: 594 SPVSSKTESVSDKEDK--PPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVA 651
+ S S E + P G P PPP P +G
Sbjct: 647 EAERAAKASSSAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIG------------- 693
Query: 652 EQVKKSTLNPNAKEFNPTKPLLSVNKSTSTP--TSPGPRTHS-----TPSIPVLTAGQSG 704
P P L + P SP R H P+ P+L G
Sbjct: 694 ----------------PDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPG 737
Query: 705 LYSPQYISYIPQIHMGPAVQAPQMYPYPV-SNSVPGQQGKYRGAKG-SLPPQRSDQHQPA 762
LY+ + P ++ ++ + + ++ + R G + P D PA
Sbjct: 738 LYN-----------VDPTIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPA 786
Query: 763 SAPP--MMQAAAAAGPPLVAATPYSSYIP-YNP---QQFPGQPAMMQPMAHYPSQPVFAP 816
+ P + +A PP P++S+ P NP ++ ++P YP +
Sbjct: 787 ANPMEHFARHSALTIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAER 846
Query: 817 MLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQP- 875
+ LTS + + + TP H + H + LH HQ P
Sbjct: 847 IHAERMASLTSDPLARLQMFNVTPH----------------HHQHSHIHSHLHLHQQDPL 890
Query: 876 ---ATTPTGSQPQSQHAAP--SPVQHQAGQAPHLGSGQP---QQNLYHPGALTGTPPSL- 926
+ P A P + + G P+ GQP + L HP T P L
Sbjct: 891 HQGSAGPVHPLVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLP 950
Query: 927 ----PPGPSAQSPQSSFPQPAAVYAI-HHQQLPHGFTNM 960
PP +A Q+ Q A + + QQ HG +M
Sbjct: 951 GAIPPPMSAAHQLQAMHAQSAELQRLAMEQQWLHGHPHM 989
Score = 45.1 bits (105), Expect = 4e-04
Identities = 39/134 (29%), Positives = 51/134 (38%), Gaps = 32/134 (23%)
Query: 2 LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNG-----------------GLPGPL-- 42
L PQ PS P QPP Q+ PP + PP G G P P+
Sbjct: 436 LMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITP 495
Query: 43 ----ATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGS 98
+TS P GP +A P AA+G + G+ P P Q +E A+
Sbjct: 496 PTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSS-----CPLPTVQIKEE----ALDD 546
Query: 99 ARGQSTGKGPPQSP 112
A + PP+SP
Sbjct: 547 AEEPESPPPPPRSP 560
Score = 41.2 bits (95), Expect = 0.005
Identities = 92/374 (24%), Positives = 125/374 (33%), Gaps = 82/374 (21%)
Query: 371 GGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPS 430
G P SS PP P +PGP A + P +G+ T S N+P
Sbjct: 192 GVTPAPSSAPPGTPQL---PTPGPTPSATAV-------------PPQGSPTASQAPNQPQ 235
Query: 431 GETSVPPPPAVGR---MYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDP 487
T+ P + + ++P R P +P P P PP+ T SA P S + P
Sbjct: 236 APTAPVPHTHIQQAPALHPQRPP---SPHPPPHPSPHPPLQPL--TGSAGQPSAPSHAQP 290
Query: 488 GVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRK 547
+ P P A ++ +P L PQ G+ P + + L+
Sbjct: 291 PLHGQGPPGPHSLQAGPLLQHPGPPQP-FGLPPQ---ASQGQAPLGTSPAAAYPHTSLQL 346
Query: 548 FGAQFKLQPSSSP-ENSLDPFP-------------------PRILKEEPK---GKEKEVD 584
+Q LQ P E L P P P+ K P ++
Sbjct: 347 PASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMN 406
Query: 585 GLLTSEPMGSPVSSKTESVSDKEDKPPL--------------APSGGTEGPEQPPPPCPS 630
L P P+SS + PPL P G T+ PPPP
Sbjct: 407 ANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPP--- 463
Query: 631 QTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTH 690
PP GL + + P A+ P PT P STSTP + GP T
Sbjct: 464 -ASHPPTGL--HQVAPQPPFAQHPFVPGGPPPITP--PTCP------STSTPPA-GPGTS 511
Query: 691 STPSIPVLTAGQSG 704
+ P P A SG
Sbjct: 512 AQP--PCSGAAASG 523
Score = 38.9 bits (89), Expect = 0.026
Identities = 38/118 (32%), Positives = 46/118 (38%), Gaps = 10/118 (8%)
Query: 4 PQPLQQPSQPQQP----PPT--QQAVA---RRPPGGTSPPNGGLPGPLATSAAPPGPPAA 54
P Q P+QPQ P P T QQA A +RPP PP+ PL G P+A
Sbjct: 225 PTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSA 284
Query: 55 ASPCLGPVAAAG-SGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS 111
S P+ G G G L P PPQ P A+ + G S P +
Sbjct: 285 PSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHT 342
Score = 37.0 bits (84), Expect = 0.097
Identities = 32/110 (29%), Positives = 41/110 (37%), Gaps = 6/110 (5%)
Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAA 65
P Q ++ QQ + + P P G P P S+APPG P +P P A A
Sbjct: 162 PSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAP---SSAPPGTPQLPTPGPTPSATA 218
Query: 66 --GSGLRRGAEGILAPQ-PPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112
G ++ PQ P P H A A+ R S P SP
Sbjct: 219 VPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSP 268
Score = 36.6 bits (83), Expect = 0.13
Identities = 30/111 (27%), Positives = 38/111 (34%), Gaps = 7/111 (6%)
Query: 9 QPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSG 68
QP Q P A + PPG P G P P AT+ P G P A+ P A
Sbjct: 183 QPPALQAPTGVTPAPSSAPPGTPQLPTPG-PTPSATAVPPQGSPTASQAPNQPQAPTAPV 241
Query: 69 LRRGAEGILA------PQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPV 113
+ A P P PP P + + GQ + Q P+
Sbjct: 242 PHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPL 292
Score = 32.3 bits (72), Expect = 2.4
Identities = 33/111 (29%), Positives = 42/111 (37%), Gaps = 15/111 (13%)
Query: 2 LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61
L P PL P + PP T P PP+ P P + +A P PPA L P
Sbjct: 364 LPPAPLAMP-HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPA-----LKP 417
Query: 62 VAAAGSGLRRGAEGILAPQPPPPQ---QHQERPGAAAIGSARGQSTGKGPP 109
+++ + A PPP Q Q Q P + A QS PP
Sbjct: 418 LSSLSTHHPPSA------HPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPP 462
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 79.3 bits (194), Expect = 2e-14
Identities = 113/436 (25%), Positives = 142/436 (32%), Gaps = 58/436 (13%)
Query: 580 EKEVDGLLTSEPMGSPVS--SKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPV 637
++E L+ P G+P +K + KP P G P+ PPPP G PP
Sbjct: 25 QEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP- 83
Query: 638 GLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPV 697
+G +K +GP + K +P P P P P+ + P P
Sbjct: 84 ---QGGNKPQGPPPPGKPQGPPPQGDKSRSPRSP-------PGKPQGPPPQGGNQPQGPP 133
Query: 698 LTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSD 757
G+ PQ + PQ GP P P ++ G PPQ +
Sbjct: 134 PPPGKPQGPPPQGGNK-PQ---GPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGN 189
Query: 758 QHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPM 817
Q Q PP GPP P P P PG+P P SQ +P
Sbjct: 190 QPQGPPPPP----GKPQGPP-----PQGGNKPQGPPP-PGKPQGPPPQGDNKSQSARSP- 238
Query: 818 LQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPAT 877
P+ G PQ + PQ P PQ P P P
Sbjct: 239 -PGKPQ----GPPPQG---GNQPQGPPPPPGKPQG---------PPPQGGNKPQGPPPPG 281
Query: 878 TPTGSQPQS---QHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPP---SLPPGPS 931
P G PQ ++ SP G P G QPQ PG G PP + P GP
Sbjct: 282 KPQGPPPQGGSKSRSSRSPPGKPQGPPPQ-GGNQPQGPPPPPGKPQGPPPQGGNKPQGPP 340
Query: 932 AQS-PQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVML 990
PQ P P + P G + + G PPP G P PQ
Sbjct: 341 PPGKPQG--PPPQGGSKSRSARSPPGKPQGPPQQEGNNPQG---PPPPAGGNPQQPQAPP 395
Query: 991 LHPPQSHGGPPQGAVP 1006
PQ PPQG P
Sbjct: 396 AGQPQGPPRPPQGGRP 411
Score = 73.6 bits (179), Expect = 9e-13
Identities = 102/393 (25%), Positives = 128/393 (32%), Gaps = 67/393 (17%)
Query: 555 QPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSS-KTESVSDKEDKPPLA 613
QP P P P + P+G K +P G P K+ S KP
Sbjct: 67 QPQGPP-----PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGP 121
Query: 614 PSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLL 673
P G P+ PPPP G PP +G +K +GP P K P P
Sbjct: 122 PPQGGNQPQGPPPPPGKPQGPPP----QGGNKPQGP----------PPPGKPQGP--PPQ 165
Query: 674 SVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQA---PQMYP 730
NKS S+ + PG P G PQ P GP Q PQ P
Sbjct: 166 GDNKSRSSRSPPGKPQGPPP---------QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP 216
Query: 731 YPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPY 790
P GK +G PPQ ++ Q A +PP GPP P P
Sbjct: 217 PP---------GKPQGP----PPQGDNKSQSARSPP----GKPQGPP-----PQGGNQPQ 254
Query: 791 NPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTP 850
P PG+P P Q P P+ G PQ S + + P + P
Sbjct: 255 GPPPPPGKPQGPPPQGGNKPQ---GPPPPGKPQ----GPPPQGGSKSRSSRSPPGKPQGP 307
Query: 851 QALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQ 910
Q P + PQ P G P + P P ++ G+PQ
Sbjct: 308 PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQ 367
Query: 911 QNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPA 943
P G P PP P+ +PQ PA
Sbjct: 368 ----GPPQQEGNNPQGPPPPAGGNPQQPQAPPA 396
Score = 68.6 bits (166), Expect = 3e-11
Identities = 110/417 (26%), Positives = 128/417 (30%), Gaps = 59/417 (14%)
Query: 650 VAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQ--SGLYS 707
VA S N N P L P G + PS P G G
Sbjct: 8 VALLALSSAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQ 67
Query: 708 PQYISYIPQIHMGPAVQA---PQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASA 764
PQ P GP Q PQ P P GK +G PPQ P S
Sbjct: 68 PQGPPPPPGKPQGPPPQGGNKPQGPPPP---------GKPQGP----PPQGDKSRSPRSP 114
Query: 765 PPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRM 824
P Q GPP P P P PG+P P Q P P+
Sbjct: 115 PGKPQ-----GPP-----PQGGNQPQGPPPPPGKPQGPPPQGGNKPQ---GPPPPGKPQ- 160
Query: 825 LTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQP 884
G PQ S + + P + P Q P + PQ P G P
Sbjct: 161 ---GPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP 217
Query: 885 QSQHAAPSPVQHQAGQA-----------PHLGSGQPQQNLYHPGALTGTPP---SLPPGP 930
+ P P Q+ P G QPQ PG G PP + P GP
Sbjct: 218 PGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGP 277
Query: 931 SAQS-PQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVM 989
PQ P P + P G + G PPP PG P P
Sbjct: 278 PPPGKPQG--PPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQG----PPPPPGKPQGPPPQ 331
Query: 990 LLHPPQS--HGGPPQGAVPQSGVPALSASTPSPYPYIGHPQVQSHPSQQLPFHPPGN 1044
+ PQ G PQG PQ G + SA +P P G PQ + + Q P GN
Sbjct: 332 GGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQ-GPPQQEGNNPQGPPPPAGGN 387
Score = 64.7 bits (156), Expect = 4e-10
Identities = 109/435 (25%), Positives = 140/435 (32%), Gaps = 57/435 (13%)
Query: 335 SGRESPSLASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGP 394
S ESPSL + + P PQ + P+G G P P+GP GP
Sbjct: 24 SQEESPSLIAGNPQGAP-PQGGNK-PQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 81
Query: 395 GSEARGINGGPSRMSPKAQRPLRGAKTLS--SPSNRPSGET--------SVPPPPAVGRM 444
+ GP P +G K+ S SP +P G PPPP +
Sbjct: 82 PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 141
Query: 445 YPPRSP-KSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAP 503
PP+ K P P PP G SS S P P G+ P P
Sbjct: 142 PPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKP 201
Query: 504 TDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFG--AQFKLQPSSSPE 561
+P P + G P N+ + + + G Q QP P
Sbjct: 202 QGPPPQGGNKP---QGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPP- 257
Query: 562 NSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPV--SSKTESVSDKEDKPPLAPSGGTE 619
P P + P+G K +P G P SK+ S KP P G
Sbjct: 258 ----PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGN 313
Query: 620 GPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKST 679
P+ PPPP G PP +G +K +GP P KP
Sbjct: 314 QPQGPPPPPGKPQGPPP----QGGNKPQGPPP----------------PGKP-------Q 346
Query: 680 STPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPG 739
P G ++ S S P G PQ PQ PA PQ P + G
Sbjct: 347 GPPPQGGSKSRSARSPPGKPQG-----PPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQG 401
Query: 740 QQGKYRGAKGSLPPQ 754
+G + S PPQ
Sbjct: 402 PPRPPQGGRPSRPPQ 416
Score = 61.2 bits (147), Expect = 5e-09
Identities = 104/431 (24%), Positives = 134/431 (31%), Gaps = 57/431 (13%)
Query: 394 PGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSA 453
P A G P + K Q P P + + PPPP PP +
Sbjct: 29 PSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK 88
Query: 454 APAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKE 513
P P+ P + S P P G P P P K
Sbjct: 89 PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGP----PPPPGKPQGPPP 144
Query: 514 PG--RTLEPQELARIAGKVPGLQNEQKRFQLEELRKFG--AQFKLQPSSSPENSLDPFPP 569
G + P + G P N+ + + + G Q QP P P P
Sbjct: 145 QGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPP-----PPPG 199
Query: 570 RILKEEPKGKEKEVDGLLTSEPMGSPV--SSKTESVSDKEDKPPLAPSGGTEGPEQPPPP 627
+ P+G K +P G P +K++S KP P G P+ PPPP
Sbjct: 200 KPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPP 259
Query: 628 CPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGP 687
G PP +G +K +GP P K P P +KS S+ + PG
Sbjct: 260 PGKPQGPPP----QGGNKPQGP----------PPPGKPQGP--PPQGGSKSRSSRSPPGK 303
Query: 688 RTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQA---PQMYPYPVSNSVPGQQGKY 744
P G PQ P GP Q PQ P P P QG
Sbjct: 304 PQGPPP---------QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGS 354
Query: 745 RGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFP-GQP--AM 801
+ PP + PP + GPP P + P PQ P GQP
Sbjct: 355 KSRSARSPPGK------PQGPPQQEGNNPQGPP-----PPAGGNPQQPQAPPAGQPQGPP 403
Query: 802 MQPMAHYPSQP 812
P PS+P
Sbjct: 404 RPPQGGRPSRP 414
Score = 48.9 bits (115), Expect = 2e-05
Identities = 42/131 (32%), Positives = 49/131 (37%), Gaps = 25/131 (19%)
Query: 3 KPQPLQQPSQPQQPPP---TQQAVARRPPG--------GTSPPNGGLPGPLATSAAPP-- 49
KPQ P +PQ PPP + AR PPG G + P G P P PP
Sbjct: 211 KPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 270
Query: 50 -----GPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQE------RPGAAAIGS 98
GPP P GP GS R PQ PPPQ + PG
Sbjct: 271 GNKPQGPPPPGKP-QGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP 329
Query: 99 ARGQSTGKGPP 109
+G + +GPP
Sbjct: 330 PQGGNKPQGPP 340
Score = 48.5 bits (114), Expect = 3e-05
Identities = 42/131 (32%), Positives = 50/131 (38%), Gaps = 22/131 (16%)
Query: 3 KPQPLQQPSQPQQPPP---TQQAVARRPPG--------GTSPPNGGLPGPLATSAAPP-- 49
KPQ P +PQ PPP ++ +R PPG G + P G P P PP
Sbjct: 273 KPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 332
Query: 50 -----GPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQ---HQERPGAAAIGSARG 101
GPP P GP GS R PQ PP Q+ Q P A +
Sbjct: 333 GNKPQGPPPPGKP-QGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQP 391
Query: 102 QSTGKGPPQSP 112
Q+ G PQ P
Sbjct: 392 QAPPAGQPQGP 402
Score = 47.8 bits (112), Expect = 6e-05
Identities = 40/133 (30%), Positives = 51/133 (38%), Gaps = 19/133 (14%)
Query: 3 KPQ--PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLP-----GP-------LATSAAP 48
KPQ P Q +QPQ PPP PP G + P G P GP ++ +P
Sbjct: 179 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSP 238
Query: 49 PG-----PPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQS 103
PG PP + GP G +G PQ PPP + P +R
Sbjct: 239 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSR 298
Query: 104 TGKGPPQSPVFEG 116
+ G PQ P +G
Sbjct: 299 SPPGKPQGPPPQG 311
Score = 47.4 bits (111), Expect = 7e-05
Identities = 40/133 (30%), Positives = 51/133 (38%), Gaps = 19/133 (14%)
Query: 3 KPQ--PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLP-----GP-------LATSAAP 48
KPQ P Q +QPQ PPP PP G + P G P GP +S +P
Sbjct: 117 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSP 176
Query: 49 PG-----PPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQS 103
PG PP + GP G +G PQ PPP + P ++
Sbjct: 177 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSAR 236
Query: 104 TGKGPPQSPVFEG 116
+ G PQ P +G
Sbjct: 237 SPPGKPQGPPPQG 249
Score = 45.4 bits (106), Expect = 3e-04
Identities = 45/131 (34%), Positives = 54/131 (41%), Gaps = 23/131 (17%)
Query: 3 KPQ--PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLP-----GP-------LATSAAP 48
KPQ P Q +QPQ PPP PP G + P G P GP +S +P
Sbjct: 241 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSP 300
Query: 49 PG-----PPAAASPCLGPVAAAGSGLRRGAEGILAPQ-PPPPQQHQERP--GAAAIGSAR 100
PG PP + GP G +G PQ PPPP + Q P G + SAR
Sbjct: 301 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSAR 360
Query: 101 G-QSTGKGPPQ 110
+GPPQ
Sbjct: 361 SPPGKPQGPPQ 371
Score = 45.1 bits (105), Expect = 4e-04
Identities = 35/109 (32%), Positives = 42/109 (38%), Gaps = 12/109 (11%)
Query: 3 KPQ--PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
KPQ P Q +QPQ PPP PP G + P G P P GPP
Sbjct: 56 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP-----PGKPQGPPPQGDKSRS 110
Query: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPP 109
P + G +G PQ PPP PG +G + +GPP
Sbjct: 111 PRSPPGKPQGPPPQGGNQPQGPPPP-----PGKPQGPPPQGGNKPQGPP 154
Score = 44.3 bits (103), Expect = 6e-04
Identities = 37/117 (31%), Positives = 47/117 (40%), Gaps = 16/117 (13%)
Query: 3 KPQ--PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPG-----PPAAA 55
KPQ P Q ++PQ PPP +P G PP GG +S +PPG PP
Sbjct: 262 KPQGPPPQGGNKPQGPPP-----PGKPQG--PPPQGG--SKSRSSRSPPGKPQGPPPQGG 312
Query: 56 SPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112
+ GP G +G PQ PPP + P +R + G PQ P
Sbjct: 313 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGP 369
Score = 43.1 bits (100), Expect = 0.001
Identities = 39/130 (30%), Positives = 47/130 (36%), Gaps = 24/130 (18%)
Query: 3 KPQPLQQPSQPQQPPPT--QQAVARRPPG--------GTSPPNGGLPGPLATSAAPP--- 49
KPQ P +PQ PPP + R PPG G + P G P P PP
Sbjct: 88 KPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 147
Query: 50 ----GPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQE------RPGAAAIGSA 99
GPP P GP + R PQ PPPQ + PG
Sbjct: 148 NKPQGPPPPGKP-QGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP 206
Query: 100 RGQSTGKGPP 109
+G + +GPP
Sbjct: 207 QGGNKPQGPP 216
Score = 37.0 bits (84), Expect = 0.097
Identities = 32/105 (30%), Positives = 39/105 (37%), Gaps = 9/105 (8%)
Query: 13 PQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRG 72
PQ PP + PP P G P P + P GPP GP G +G
Sbjct: 36 PQGAPPQGGNKPQGPPSPPGKPQG--PPPQGGN-QPQGPPPPPGKPQGP-PPQGGNKPQG 91
Query: 73 AEGILAPQPPPPQQHQER-----PGAAAIGSARGQSTGKGPPQSP 112
PQ PPPQ + R PG +G + +GPP P
Sbjct: 92 PPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPP 136
Score = 31.6 bits (70), Expect = 4.1
Identities = 21/61 (34%), Positives = 24/61 (39%), Gaps = 12/61 (19%)
Query: 3 KPQ--PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
KPQ P Q+ + PQ PP PP G +P P P PP PP P
Sbjct: 365 KPQGPPQQEGNNPQGPP---------PPAGGNPQQPQAP-PAGQPQGPPRPPQGGRPSRP 414
Query: 61 P 61
P
Sbjct: 415 P 415
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 77.8 bits (190), Expect = 5e-14
Identities = 141/597 (23%), Positives = 204/597 (34%), Gaps = 104/597 (17%)
Query: 490 GSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEEL---R 546
G SP +S + +D K +++ + +E + G E + EE +
Sbjct: 31 GRASPGG--VSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPK 88
Query: 547 KFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVD--GLLTSEPMGSPVSSKTESVS 604
K + +L SP + LD R L ++ +++D TS + SP S + +S S
Sbjct: 89 KTKTEQELPRPQSPSD-LDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDS 147
Query: 605 DKEDKPPLAPSGGTEGPEQP--PPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPN 662
SG ++GP +P PPP + PP + P A ++ P
Sbjct: 148 S---------SGLSQGPARPYHPPPLFPPSPQPP------DSTPRQPEASFEPHPSVTPT 192
Query: 663 AKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPA 722
P + ++ P P+ + + VL+ G S + + G
Sbjct: 193 GYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQ 252
Query: 723 VQAPQMYPYPVSNSVPGQQGKYR----------GAKGSLPPQRSDQHQPASAPPMMQAA- 771
P P+S S G G G S PP + H + PP
Sbjct: 253 HPPPTT---PISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRP 309
Query: 772 ---AAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRML--- 825
A+A PP + A P P P AM Q M P P P L +P L
Sbjct: 310 LNNASASPPGLGAQPL-------PGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPA 362
Query: 826 -------------TSGSHPQAIVSSSTPQYPSAEQPTP--QALYATVHQSYPHHATQLHA 870
+S S A SSS+ S+ P P QAL SYPH
Sbjct: 363 SSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQAL-----PSYPHSF----- 412
Query: 871 HQPQPATTPTGSQPQ--SQHAAPSPVQHQAGQAPHLGSGQPQQNLY-HPGALTGTPPSLP 927
P P + +QP +Q + PS G P G+ N HPG
Sbjct: 413 --PPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPG---------- 460
Query: 928 PGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQ 987
P P + QS+ P + + HHQQ Q Q + PPP PHP +
Sbjct: 461 PFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLE 520
Query: 988 VMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP--YPYIGHPQVQSHPSQQLPFHPP 1042
GG A P + P+L + P P ++ P Q SQ P PP
Sbjct: 521 ----------GGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPP 567
Score = 65.1 bits (157), Expect = 3e-10
Identities = 146/633 (23%), Positives = 197/633 (31%), Gaps = 114/633 (18%)
Query: 371 GGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPS 430
GG G+ S PP GP G S G NGG P + + +P +P
Sbjct: 222 GGTGGVLSGPPMGP-----KGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKP- 275
Query: 431 GETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVG 490
P VG P +P A ++ + P PP + +SAS P + PG
Sbjct: 276 ------PTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPG-- 327
Query: 491 SISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGA 550
P+ + + K P P L + P RF A
Sbjct: 328 -HLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPA---PPMRFPYSSSSSSSA 383
Query: 551 QFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKP 610
SSS +S PFP L S P P P
Sbjct: 384 AAS-SSSSSSSSSASPFP--------------ASQALPSYPHSFP--------------P 414
Query: 611 PLAPSGGTEGPEQPPPPCPSQT----GSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEF 666
P + S + P+ P PSQ G PP P + S +P
Sbjct: 415 PTSLSVSNQPPKYTQPSLPSQAVWSQGPPP----------PPPYGRLLANSNAHP----- 459
Query: 667 NPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAP 726
P P + P S H Q Q Q H P
Sbjct: 460 GPFPPSTGAQSTAHPPVSTHHHHHQQQQ-------QQQQQQQQQQQQQQQHHGNSGPPPP 512
Query: 727 QMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPP-----MMQAAAAAGPPLVAA 781
+P+P+ Y SL R PA PP A GPP+ ++
Sbjct: 513 GAFPHPLEGGSSHHAHPY-AMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSS 571
Query: 782 TPYSSYIPYN--PQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSST 839
+ SS P P P+ A YP PV P + ++ L S A V+SS
Sbjct: 572 SNSSSSTSQGSYPCSHP-SPSQGPQGAPYPFPPV--PTVTTSSATL---STVIATVASSP 625
Query: 840 PQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAG 899
Y +A P P P + + + TP G +P SP + G
Sbjct: 626 AGYKTASPPGP-----------PPYGKRAPSPGAYKTATPPGYKP------GSPPSFRTG 668
Query: 900 QAP-HLGSGQPQ-QNLYHPGALTGTPPSLPP-GPSAQSPQSSFPQPAAVYAIHHQQLPHG 956
P + G+ P + PG+ T P LPP GPS S P P A A P
Sbjct: 669 TPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSG---LPSLPPPPAAPA---SGPPLS 722
Query: 957 FTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVM 989
T + +T + PP +P PP+V+
Sbjct: 723 ATQIKQEPAEEYETPESPVPPARSPSP-PPKVV 754
Score = 60.1 bits (144), Expect = 1e-08
Identities = 131/564 (23%), Positives = 178/564 (31%), Gaps = 123/564 (21%)
Query: 359 GPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNS----SPGPGSEARGINGG---------- 404
GP+GG SS G G PP P + +S +P + GG
Sbjct: 234 GPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPAN 293
Query: 405 -----PSRMSPKAQRPLRGAKT-------------LSSPSNRPSGETSVPPPPAVGRMYP 446
P+ P A RPL A L SP G +PP P G
Sbjct: 294 FPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLA 353
Query: 447 PRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDV 506
P SP S PA S+S P PP+ P +SS S S S +S S +P
Sbjct: 354 P-SPHSLPPA--SSSAPAPPM---------RFPYSSSSSSSAAASSSSSSSSSSASPFPA 401
Query: 507 KELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSL-- 564
+ P P L+ + N+ ++ L + P P L
Sbjct: 402 SQALPSYPHSFPPPTSLS--------VSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLA 453
Query: 565 ------DPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSS-----KTESVSDKEDKPPLA 613
PFPP T+ P PVS+ + + ++ +
Sbjct: 454 NSNAHPGPFPP------------STGAQSTAHP---PVSTHHHHHQQQQQQQQQQQQQQQ 498
Query: 614 PSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLL 673
G PPPP G+ P L G P A +L P P P
Sbjct: 499 QQQQHHGNSGPPPP-----GAFPHPLEGGSSHHAHPYAMSPSLGSLRP-----YPPGP-- 546
Query: 674 SVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYP- 732
P S + + P+ P +++ + S SY P H P+ Q PQ PYP
Sbjct: 547 ---AHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSY-PCSHPSPS-QGPQGAPYPF 601
Query: 733 ------------VSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAG----- 775
+S + G K + PP + A +P + A G
Sbjct: 602 PPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGS 661
Query: 776 -PPLVAATP---YSSYIPYNPQQF-PGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSH 830
P TP + P P F PG P + P P+ P P L P SG
Sbjct: 662 PPSFRTGTPPGYRGTSPPAGPGTFKPGSPT-VGPGPLPPAGPSGLPSLPPPPAAPASGPP 720
Query: 831 PQAIVSSSTP--QYPSAEQPTPQA 852
A P +Y + E P P A
Sbjct: 721 LSATQIKQEPAEEYETPESPVPPA 744
Score = 40.8 bits (94), Expect = 0.007
Identities = 133/590 (22%), Positives = 201/590 (34%), Gaps = 102/590 (17%)
Query: 351 PLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSP 410
P P R G + ++ G +PG P +P PG GP P
Sbjct: 636 PPPYGKRAPSPGAYKTATPPGYKPG-------SPPSFRTGTP-PGYRGTSPPAGPGTFKP 687
Query: 411 KAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKS------------AAPAPI 458
+ P G L P PSG S+PPPPA PP S +P P
Sbjct: 688 GS--PTVGPGPL--PPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPP 743
Query: 459 SASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRT- 517
+ S PP VP+ ++ + D G S A + P + +L+ K
Sbjct: 744 ARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSC--ARSDLYFVPLEGSKLAKKRADLVE 801
Query: 518 ---LEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKL-QPSSSPEN--SLDPFPPRI 571
E ++ AR + + +K + E+ R+ KL Q +P SL P P R
Sbjct: 802 KVRREAEQRAREEKEREREREREKEREREKERELERSVKLAQEGRAPVECPSLGPVPHRP 861
Query: 572 LKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPC--P 629
E + T P P + ++S+ +P + G P P P
Sbjct: 862 PFEPG-------SAVATVPPYLGPDTPALRTLSEYA-RPHVMSPGNRNHPFYVPLGAVDP 913
Query: 630 SQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTS--PGP 687
G L + P A + ++ + ++ KP V S P PGP
Sbjct: 914 GLLGYNVPALYSSD-----PAAREREREARERDLRD--RLKPGFEVKPSELEPLHGVPGP 966
Query: 688 RTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQ--APQMYPYPVSNSV-PGQQGKY 744
P H G A+Q P ++P+P S+ P ++ +
Sbjct: 967 GLDPFPR-----------------------HGGLALQPGPPGLHPFPFHPSLGPLERERL 1003
Query: 745 RGAKG-SLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQ--QFPGQPAM 801
A G +L P S + A+ + AA G +A + P++ Q +
Sbjct: 1004 ALAAGPALRPDMSYAERLAAERQHAERVAALGNDPLARLQMLNVTPHHHQHSHIHSHLHL 1063
Query: 802 MQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSY 861
Q A + + P++ L SGSH I YP+ P P +
Sbjct: 1064 HQQDAIHAASASVHPLIDP----LASGSHLTRI------PYPAGTLPNPLL-------PH 1106
Query: 862 PHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQ 911
P H ++ HQ A P P S +AP HQ QA H S + Q+
Sbjct: 1107 PLHENEVLRHQLFAA--PYRDLPASL-SAPMSAAHQL-QAMHAQSAELQR 1152
Score = 40.4 bits (93), Expect = 0.009
Identities = 68/298 (22%), Positives = 92/298 (30%), Gaps = 41/298 (13%)
Query: 385 HHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRM 444
HH ++ P PG+ + GG S + P + +L S P G +PPP
Sbjct: 503 HHGNSGPPPPGAFPHPLEGGSSHHA----HPYAMSPSLGSLRPYPPGPAHLPPP------ 552
Query: 445 YPPRSPKSAAP--APISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLA 502
+ S A P P+S+S S+ TS S P + G P +
Sbjct: 553 HSQVSYSQAGPNGPPVSSSS-----NSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTV 607
Query: 503 PTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPEN 562
T LST T+ PG KR K +P S
Sbjct: 608 TTSSATLSTVIA--TVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGS---- 661
Query: 563 SLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPE 622
PP P G TS P G PP PSG P
Sbjct: 662 -----PPSFRTGTPPGYRG------TSPPAGPGTFKPGSPTVGPGPLPPAGPSGL---PS 707
Query: 623 QPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTS 680
PPPP +G P + + P E + P A+ +P ++ V S
Sbjct: 708 LPPPPAAPASGPP----LSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHAS 761
Score = 37.0 bits (84), Expect = 0.097
Identities = 31/95 (32%), Positives = 37/95 (38%), Gaps = 18/95 (18%)
Query: 12 QPQQPPPTQQAVARRPPG--GTSPPNGGL----------PGPL---ATSAAPPGPPAAAS 56
+P PP + PPG GTSPP G PGPL S P PP A+
Sbjct: 658 KPGSPPSFRTGT---PPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAA 714
Query: 57 PCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERP 91
P GP +A + AE P+ P P P
Sbjct: 715 PASGPPLSATQIKQEPAEEYETPESPVPPARSPSP 749
Score = 35.8 bits (81), Expect = 0.22
Identities = 22/52 (42%), Positives = 25/52 (48%), Gaps = 6/52 (11%)
Query: 4 PQPLQQ--PSQPQQ-PPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPP 52
P P Q PS P PPPT +V+ +PP T P LP S PP PP
Sbjct: 398 PFPASQALPSYPHSFPPPTSLSVSNQPPKYTQP---SLPSQAVWSQGPPPPP 446
Score = 35.8 bits (81), Expect = 0.22
Identities = 32/104 (30%), Positives = 37/104 (35%), Gaps = 19/104 (18%)
Query: 8 QQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGS 67
QQ Q QQ QQ + PP G P PL ++ P A SP LG
Sbjct: 485 QQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGS------ 538
Query: 68 GLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS 111
L P PP P H P + S G + GPP S
Sbjct: 539 ---------LRPYPPGP-AHLPPPHSQVSYSQAGPN---GPPVS 569
Score = 33.9 bits (76), Expect = 0.82
Identities = 34/113 (30%), Positives = 42/113 (37%), Gaps = 16/113 (14%)
Query: 4 PQPLQQPS-QPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPV 62
P PL PS QP P Q + P +P P TS PP A P P
Sbjct: 161 PPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPP--HPQ 218
Query: 63 AAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGK--GPPQSPV 113
G G G+L+ P P+ G A S G + GK PP +P+
Sbjct: 219 LYPG-----GTGGVLSGPPMGPK------GGGAASSVGGPNGGKQHPPPTTPI 260
Score = 33.1 bits (74), Expect = 1.4
Identities = 28/96 (29%), Positives = 31/96 (32%), Gaps = 3/96 (3%)
Query: 14 QQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGA 73
Q PPPT +PP P+ P PP A P + P LR
Sbjct: 252 QHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLN 311
Query: 74 EGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPP 109
A PP Q PG A GQ G PP
Sbjct: 312 N---ASASPPGLGAQPLPGHLPSPHAMGQGMGGLPP 344
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 77.8 bits (190), Expect = 5e-14
Identities = 141/597 (23%), Positives = 204/597 (34%), Gaps = 104/597 (17%)
Query: 490 GSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEEL---R 546
G SP +S + +D K +++ + +E + G E + EE +
Sbjct: 31 GRASPGG--VSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPK 88
Query: 547 KFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVD--GLLTSEPMGSPVSSKTESVS 604
K + +L SP + LD R L ++ +++D TS + SP S + +S S
Sbjct: 89 KTKTEQELPRPQSPSD-LDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDS 147
Query: 605 DKEDKPPLAPSGGTEGPEQP--PPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPN 662
SG ++GP +P PPP + PP + P A ++ P
Sbjct: 148 S---------SGLSQGPARPYHPPPLFPPSPQPP------DSTPRQPEASFEPHPSVTPT 192
Query: 663 AKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPA 722
P + ++ P P+ + + VL+ G S + + G
Sbjct: 193 GYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQ 252
Query: 723 VQAPQMYPYPVSNSVPGQQGKYR----------GAKGSLPPQRSDQHQPASAPPMMQAA- 771
P P+S S G G G S PP + H + PP
Sbjct: 253 HPPPTT---PISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRP 309
Query: 772 ---AAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRML--- 825
A+A PP + A P P P AM Q M P P P L +P L
Sbjct: 310 LNNASASPPGLGAQPL-------PGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPA 362
Query: 826 -------------TSGSHPQAIVSSSTPQYPSAEQPTP--QALYATVHQSYPHHATQLHA 870
+S S A SSS+ S+ P P QAL SYPH
Sbjct: 363 SSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQAL-----PSYPHSF----- 412
Query: 871 HQPQPATTPTGSQPQ--SQHAAPSPVQHQAGQAPHLGSGQPQQNLY-HPGALTGTPPSLP 927
P P + +QP +Q + PS G P G+ N HPG
Sbjct: 413 --PPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPG---------- 460
Query: 928 PGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQ 987
P P + QS+ P + + HHQQ Q Q + PPP PHP +
Sbjct: 461 PFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLE 520
Query: 988 VMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP--YPYIGHPQVQSHPSQQLPFHPP 1042
GG A P + P+L + P P ++ P Q SQ P PP
Sbjct: 521 ----------GGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPP 567
Score = 65.1 bits (157), Expect = 3e-10
Identities = 146/633 (23%), Positives = 197/633 (31%), Gaps = 114/633 (18%)
Query: 371 GGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPS 430
GG G+ S PP GP G S G NGG P + + +P +P
Sbjct: 222 GGTGGVLSGPPMGP-----KGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKP- 275
Query: 431 GETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVG 490
P VG P +P A ++ + P PP + +SAS P + PG
Sbjct: 276 ------PTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPG-- 327
Query: 491 SISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGA 550
P+ + + K P P L + P RF A
Sbjct: 328 -HLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPA---PPMRFPYSSSSSSSA 383
Query: 551 QFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKP 610
SSS +S PFP L S P P P
Sbjct: 384 AAS-SSSSSSSSSASPFP--------------ASQALPSYPHSFP--------------P 414
Query: 611 PLAPSGGTEGPEQPPPPCPSQT----GSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEF 666
P + S + P+ P PSQ G PP P + S +P
Sbjct: 415 PTSLSVSNQPPKYTQPSLPSQAVWSQGPPP----------PPPYGRLLANSNAHP----- 459
Query: 667 NPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAP 726
P P + P S H Q Q Q H P
Sbjct: 460 GPFPPSTGAQSTAHPPVSTHHHHHQQQQ-------QQQQQQQQQQQQQQQHHGNSGPPPP 512
Query: 727 QMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPP-----MMQAAAAAGPPLVAA 781
+P+P+ Y SL R PA PP A GPP+ ++
Sbjct: 513 GAFPHPLEGGSSHHAHPY-AMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSS 571
Query: 782 TPYSSYIPYN--PQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSST 839
+ SS P P P+ A YP PV P + ++ L S A V+SS
Sbjct: 572 SNSSSSTSQGSYPCSHP-SPSQGPQGAPYPFPPV--PTVTTSSATL---STVIATVASSP 625
Query: 840 PQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAG 899
Y +A P P P + + + TP G +P SP + G
Sbjct: 626 AGYKTASPPGP-----------PPYGKRAPSPGAYKTATPPGYKP------GSPPSFRTG 668
Query: 900 QAP-HLGSGQPQ-QNLYHPGALTGTPPSLPP-GPSAQSPQSSFPQPAAVYAIHHQQLPHG 956
P + G+ P + PG+ T P LPP GPS S P P A A P
Sbjct: 669 TPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSG---LPSLPPPPAAPA---SGPPLS 722
Query: 957 FTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVM 989
T + +T + PP +P PP+V+
Sbjct: 723 ATQIKQEPAEEYETPESPVPPARSPSP-PPKVV 754
Score = 60.1 bits (144), Expect = 1e-08
Identities = 131/564 (23%), Positives = 178/564 (31%), Gaps = 123/564 (21%)
Query: 359 GPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNS----SPGPGSEARGINGG---------- 404
GP+GG SS G G PP P + +S +P + GG
Sbjct: 234 GPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPAN 293
Query: 405 -----PSRMSPKAQRPLRGAKT-------------LSSPSNRPSGETSVPPPPAVGRMYP 446
P+ P A RPL A L SP G +PP P G
Sbjct: 294 FPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLA 353
Query: 447 PRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDV 506
P SP S PA S+S P PP+ P +SS S S S +S S +P
Sbjct: 354 P-SPHSLPPA--SSSAPAPPM---------RFPYSSSSSSSAAASSSSSSSSSSASPFPA 401
Query: 507 KELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSL-- 564
+ P P L+ + N+ ++ L + P P L
Sbjct: 402 SQALPSYPHSFPPPTSLS--------VSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLA 453
Query: 565 ------DPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSS-----KTESVSDKEDKPPLA 613
PFPP T+ P PVS+ + + ++ +
Sbjct: 454 NSNAHPGPFPP------------STGAQSTAHP---PVSTHHHHHQQQQQQQQQQQQQQQ 498
Query: 614 PSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLL 673
G PPPP G+ P L G P A +L P P P
Sbjct: 499 QQQQHHGNSGPPPP-----GAFPHPLEGGSSHHAHPYAMSPSLGSLRP-----YPPGP-- 546
Query: 674 SVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYP- 732
P S + + P+ P +++ + S SY P H P+ Q PQ PYP
Sbjct: 547 ---AHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSY-PCSHPSPS-QGPQGAPYPF 601
Query: 733 ------------VSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAG----- 775
+S + G K + PP + A +P + A G
Sbjct: 602 PPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGS 661
Query: 776 -PPLVAATP---YSSYIPYNPQQF-PGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSH 830
P TP + P P F PG P + P P+ P P L P SG
Sbjct: 662 PPSFRTGTPPGYRGTSPPAGPGTFKPGSPT-VGPGPLPPAGPSGLPSLPPPPAAPASGPP 720
Query: 831 PQAIVSSSTP--QYPSAEQPTPQA 852
A P +Y + E P P A
Sbjct: 721 LSATQIKQEPAEEYETPESPVPPA 744
Score = 40.8 bits (94), Expect = 0.007
Identities = 133/590 (22%), Positives = 201/590 (34%), Gaps = 102/590 (17%)
Query: 351 PLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSP 410
P P R G + ++ G +PG P +P PG GP P
Sbjct: 636 PPPYGKRAPSPGAYKTATPPGYKPG-------SPPSFRTGTP-PGYRGTSPPAGPGTFKP 687
Query: 411 KAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKS------------AAPAPI 458
+ P G L P PSG S+PPPPA PP S +P P
Sbjct: 688 GS--PTVGPGPL--PPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPP 743
Query: 459 SASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRT- 517
+ S PP VP+ ++ + D G S A + P + +L+ K
Sbjct: 744 ARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSC--ARSDLYFVPLEGSKLAKKRADLVE 801
Query: 518 ---LEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKL-QPSSSPEN--SLDPFPPRI 571
E ++ AR + + +K + E+ R+ KL Q +P SL P P R
Sbjct: 802 KVRREAEQRAREEKEREREREREKEREREKERELERSVKLAQEGRAPVECPSLGPVPHRP 861
Query: 572 LKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPC--P 629
E + T P P + ++S+ +P + G P P P
Sbjct: 862 PFEPG-------SAVATVPPYLGPDTPALRTLSEYA-RPHVMSPGNRNHPFYVPLGAVDP 913
Query: 630 SQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTS--PGP 687
G L + P A + ++ + ++ KP V S P PGP
Sbjct: 914 GLLGYNVPALYSSD-----PAAREREREARERDLRD--RLKPGFEVKPSELEPLHGVPGP 966
Query: 688 RTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQ--APQMYPYPVSNSV-PGQQGKY 744
P H G A+Q P ++P+P S+ P ++ +
Sbjct: 967 GLDPFPR-----------------------HGGLALQPGPPGLHPFPFHPSLGPLERERL 1003
Query: 745 RGAKG-SLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQ--QFPGQPAM 801
A G +L P S + A+ + AA G +A + P++ Q +
Sbjct: 1004 ALAAGPALRPDMSYAERLAAERQHAERVAALGNDPLARLQMLNVTPHHHQHSHIHSHLHL 1063
Query: 802 MQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSY 861
Q A + + P++ L SGSH I YP+ P P +
Sbjct: 1064 HQQDAIHAASASVHPLIDP----LASGSHLTRI------PYPAGTLPNPLL-------PH 1106
Query: 862 PHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQ 911
P H ++ HQ A P P S +AP HQ QA H S + Q+
Sbjct: 1107 PLHENEVLRHQLFAA--PYRDLPASL-SAPMSAAHQL-QAMHAQSAELQR 1152
Score = 40.4 bits (93), Expect = 0.009
Identities = 68/298 (22%), Positives = 92/298 (30%), Gaps = 41/298 (13%)
Query: 385 HHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRM 444
HH ++ P PG+ + GG S + P + +L S P G +PPP
Sbjct: 503 HHGNSGPPPPGAFPHPLEGGSSHHA----HPYAMSPSLGSLRPYPPGPAHLPPP------ 552
Query: 445 YPPRSPKSAAP--APISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLA 502
+ S A P P+S+S S+ TS S P + G P +
Sbjct: 553 HSQVSYSQAGPNGPPVSSSS-----NSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTV 607
Query: 503 PTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPEN 562
T LST T+ PG KR K +P S
Sbjct: 608 TTSSATLSTVIA--TVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGS---- 661
Query: 563 SLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPE 622
PP P G TS P G PP PSG P
Sbjct: 662 -----PPSFRTGTPPGYRG------TSPPAGPGTFKPGSPTVGPGPLPPAGPSGL---PS 707
Query: 623 QPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTS 680
PPPP +G P + + P E + P A+ +P ++ V S
Sbjct: 708 LPPPPAAPASGPP----LSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHAS 761
Score = 37.0 bits (84), Expect = 0.097
Identities = 31/95 (32%), Positives = 37/95 (38%), Gaps = 18/95 (18%)
Query: 12 QPQQPPPTQQAVARRPPG--GTSPPNGGL----------PGPL---ATSAAPPGPPAAAS 56
+P PP + PPG GTSPP G PGPL S P PP A+
Sbjct: 658 KPGSPPSFRTGT---PPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAA 714
Query: 57 PCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERP 91
P GP +A + AE P+ P P P
Sbjct: 715 PASGPPLSATQIKQEPAEEYETPESPVPPARSPSP 749
Score = 35.8 bits (81), Expect = 0.22
Identities = 22/52 (42%), Positives = 25/52 (48%), Gaps = 6/52 (11%)
Query: 4 PQPLQQ--PSQPQQ-PPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPP 52
P P Q PS P PPPT +V+ +PP T P LP S PP PP
Sbjct: 398 PFPASQALPSYPHSFPPPTSLSVSNQPPKYTQP---SLPSQAVWSQGPPPPP 446
Score = 35.8 bits (81), Expect = 0.22
Identities = 32/104 (30%), Positives = 37/104 (35%), Gaps = 19/104 (18%)
Query: 8 QQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGS 67
QQ Q QQ QQ + PP G P PL ++ P A SP LG
Sbjct: 485 QQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGS------ 538
Query: 68 GLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS 111
L P PP P H P + S G + GPP S
Sbjct: 539 ---------LRPYPPGP-AHLPPPHSQVSYSQAGPN---GPPVS 569
Score = 33.9 bits (76), Expect = 0.82
Identities = 34/113 (30%), Positives = 42/113 (37%), Gaps = 16/113 (14%)
Query: 4 PQPLQQPS-QPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPV 62
P PL PS QP P Q + P +P P TS PP A P P
Sbjct: 161 PPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPP--HPQ 218
Query: 63 AAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGK--GPPQSPV 113
G G G+L+ P P+ G A S G + GK PP +P+
Sbjct: 219 LYPG-----GTGGVLSGPPMGPK------GGGAASSVGGPNGGKQHPPPTTPI 260
Score = 33.1 bits (74), Expect = 1.4
Identities = 28/96 (29%), Positives = 31/96 (32%), Gaps = 3/96 (3%)
Query: 14 QQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGA 73
Q PPPT +PP P+ P PP A P + P LR
Sbjct: 252 QHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLN 311
Query: 74 EGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPP 109
A PP Q PG A GQ G PP
Sbjct: 312 N---ASASPPGLGAQPLPGHLPSPHAMGQGMGGLPP 344
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 75.9 bits (185), Expect = 2e-13
Identities = 163/679 (24%), Positives = 235/679 (34%), Gaps = 159/679 (23%)
Query: 375 GLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETS 434
GL++ G SP + G+ S++S + +R + A +S P G S
Sbjct: 15 GLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQI--AAVMSRAQGLPKG--S 70
Query: 435 VPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISP 494
VPP A SP + +S P P S P DPG P
Sbjct: 71 VPPAAA-------ESPSMHRKQELDSSHP--------PKQSGRPP------DPG----RP 105
Query: 495 ASPKISLA-PTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKF----G 549
A P +S + TD K PGR+ P ++ L+ + R L+E K G
Sbjct: 106 AQPGLSKSRTTDTFRSEQKLPGRS--PSTIS--------LKESKSRTDLKEEHKSSMMPG 155
Query: 550 AQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKED- 608
++ S+ + ++ F P L + + ++E ++K + V KE
Sbjct: 156 FLSEVNALSAVSSVVNKFNPFDLISDSEASQEE--------------TTKKQKVVQKEQG 201
Query: 609 ------KPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPN 662
KPPL +QPP P P Q G G D P+ + +++
Sbjct: 202 KPEGIIKPPLQ--------QQPPKPIPKQQG-------PGRD----PLQQDGTPKSISSQ 242
Query: 663 AKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPA 722
E ++P K PT H+ +P+ Q + PQ
Sbjct: 243 QPEKIKSQP-PGTGKPIQGPTQTPQTDHA--KLPL-----------QRDASRPQTKQADI 288
Query: 723 VQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAAT 782
V+ + P S S P Q G + P ++ QP A P Q + P +A
Sbjct: 289 VRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGH-EKSQPGPAKPPAQPSGLTKP--LAQQ 345
Query: 783 PYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQY 842
P + P P PG ++P P+ + P +GS +
Sbjct: 346 PGTVKPPVQP---PG-----------TTKPPAQPLGPAKPPAQQTGS-----------EK 380
Query: 843 PSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAG-QA 901
PS+EQP P+AL + P + A QP PA PT Q P P+ Q G Q+
Sbjct: 381 PSSEQPGPKAL------AQPPGVGKTPAQQPGPAKPPT-----QQVGTPKPLAQQPGLQS 429
Query: 902 PHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMA 961
P G + + PG G P+ GP S Q + P QLP
Sbjct: 430 PAKAPGPTKTPVQQPG--PGKIPAQQAGPGKTSAQQTGPTKPP------SQLP------G 475
Query: 962 HVTQAHVQTGITAAPPPHPGAPHPP--QVMLLHPPQSHGGPPQGAVPQSGVPALSASTPS 1019
Q G PP PG+ PP Q PP GP + + Q G S PS
Sbjct: 476 PAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPG----STKPPS 531
Query: 1020 PYPYIGHPQVQSHPSQQLP 1038
P P Q PS P
Sbjct: 532 QQPGSAKPSAQ-QPSPAKP 549
Score = 68.9 bits (167), Expect = 2e-11
Identities = 157/690 (22%), Positives = 231/690 (33%), Gaps = 123/690 (17%)
Query: 333 QGSGRESPSLASREGKYIPLPQRVREGPR---GGVRCSSSRGG-------RPGLSSLPPR 382
Q +G E PS K + P V + P G + + + G +PGL S P +
Sbjct: 374 QQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQS-PAK 432
Query: 383 --GPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGET--SVPPP 438
GP PGPG + GP + S + P + L P+ P + + PPP
Sbjct: 433 APGPTKTPVQQPGPG-KIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPP 491
Query: 439 PAVGRMYPP-----------RSPKSAAPAPISASCPEPPI---GSAVPTSSASIPV---- 480
G PP + P A P+P +PP GSA P++ P
Sbjct: 492 QQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSA 551
Query: 481 ---TSSVSDPGVG------SISPAS--------PK--ISLAPTDVKELSTKEPGRTLEPQ 521
T VS G G ++SP++ PK L T L E
Sbjct: 552 QQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCT 611
Query: 522 ELARIAGKVPGLQNEQKRFQLEELRKFGAQFK------LQP-SSSPENSLDPFP----PR 570
E + G +++E Q K L P SSP+ L P
Sbjct: 612 ECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSA 671
Query: 571 ILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEG-----PEQPP 625
+ K P+ ++ TS + + + PPL G +QPP
Sbjct: 672 VSKSSPQPQQ-------TSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPP 724
Query: 626 PPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSP 685
+PP ++D+ PVA+ K K PT L+S + +T+ P P
Sbjct: 725 EADSLSKPAPPKEPSVPSEQDKAPVADDKPK-----QPKMVKPTTDLVSSSSATTKPDIP 779
Query: 686 GPRTHS------TPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPG 739
+ S TP + +A S + P P A+ P +S+ PG
Sbjct: 780 SSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSP--FDSKAIPRPASDSKIISH--PG 835
Query: 740 QQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQP 799
+ +G K P Q+ + +P A M A P P S P P+ GQ
Sbjct: 836 PSSESKGQKQVDPVQKKE--EPKKAQTKMSPKPDAKP-----MPKGSPTPPGPRPTAGQT 888
Query: 800 AMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQ 859
+ P + QS L GS ++ + P+ Q T
Sbjct: 889 VPTPQQSPKPQE-------QSRRFSLNLGS-----ITDAPKSQPTTPQETVTGKLFGFGA 936
Query: 860 SYPHHATQL--HAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPG 917
S A+ L A QP P + P Q AP+P Q Q P +GQ
Sbjct: 937 SIFSQASNLISTAGQPGPHSQSGPGAPMKQ--APAPSQPPTSQGPPKSTGQ--------- 985
Query: 918 ALTGTPPSLPPGPSAQSPQSSFPQPAAVYA 947
A S+P ++P + +P A A
Sbjct: 986 APPAPAKSIPVKKETKAPAAEKLEPKAEQA 1015
Score = 59.3 bits (142), Expect = 2e-08
Identities = 145/670 (21%), Positives = 207/670 (30%), Gaps = 132/670 (19%)
Query: 405 PSRMSPKAQRPLRG-----AKTLSSPSNRPSGETSVPP---PPAVGRMYPPRSPKSAAPA 456
P + PK Q P R S S +P S PP P G P++ + P
Sbjct: 215 PPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPL 274
Query: 457 PISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGR 516
AS P+ V S P S S P + +P P + + +P
Sbjct: 275 QRDASRPQTKQADIVRGESVK-PSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKP-- 331
Query: 517 TLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEP 576
+P L + + PG + Q K AQ L P+ P P + P
Sbjct: 332 PAQPSGLTKPLAQQPG--TVKPPVQPPGTTKPPAQ-PLGPAKPPAQQTGSEKPSSEQPGP 388
Query: 577 KGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPP 636
K + T P T+ V + PLA G + P + P P + P
Sbjct: 389 KALAQPPGVGKTPAQQPGPAKPPTQQVGTPK---PLAQQPGLQSPAKAPGPTKTPVQQPG 445
Query: 637 VGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIP 696
G I + G +A++ PTKP + PGP
Sbjct: 446 PGKIPAQQAGPG-----------KTSAQQTGPTKPPSQL---------PGP--------- 476
Query: 697 VLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRS 756
+ P GPA PQ P S P QQ GS P
Sbjct: 477 ---------------AKPPPQQPGPAKPPPQQ---PGSAKPPSQQ------PGSTKP--- 509
Query: 757 DQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAP 816
QP A P Q + PP QP +P A PS +
Sbjct: 510 PPQQPGPAKPSPQQPGSTKPP------------------SQQPGSAKPSAQQPSPAKPSA 551
Query: 817 MLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPA 876
+ P T P + S PSA+QP Q L T+ + T+L H P+ A
Sbjct: 552 QQSTKPVSQTGSGKPLQPPTVS----PSAKQPPSQGLPKTICPLC--NTTELLLHVPEKA 605
Query: 877 TTPTGSQPQSQHAA-----PSPVQHQAGQ----------------APHLGSGQPQQNLYH 915
T ++ Q+ + P+P + + AP S QP+
Sbjct: 606 NFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKT-A 664
Query: 916 PGALTGTPPSLPPGPSAQSPQ---------SSFPQPAAVYAIHHQQLPHGFTNMAHVTQA 966
P T P P SP+ S P+P + Q HG +
Sbjct: 665 PVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPP 724
Query: 967 HVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGH 1026
+ APP P P P + P Q + + +S+S+ + P I
Sbjct: 725 EADSLSKPAPPKEPSVPSEQD----KAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPS 780
Query: 1027 PQVQSHPSQQ 1036
+VQS ++
Sbjct: 781 SKVQSQAEEK 790
Score = 55.1 bits (131), Expect = 3e-07
Identities = 99/449 (22%), Positives = 159/449 (35%), Gaps = 78/449 (17%)
Query: 373 RPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGE 432
+P L + P + SSP P + + P + KA P + + P+ S
Sbjct: 658 QPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPS 717
Query: 433 TSVPPPPAVGRMYPPRSPKSAA------PAPISASCPEPPIGSAVPTSSASIPVTSSVSD 486
PP + P PK + AP++ P+ P V ++ + +S+ +
Sbjct: 718 AKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQP--KMVKPTTDLVSSSSATTK 775
Query: 487 PGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELR 546
P + S S +K S K P ++ P E++
Sbjct: 776 PDIPSSKVQSQAEEKTTPPLKTDSAK-PSQSFPPTG--------------------EKVS 814
Query: 547 KFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDK 606
F ++ +P+S + P P E KG +K+VD + E P ++T+ +S K
Sbjct: 815 PFDSKAIPRPASDSKIISHPGP----SSESKG-QKQVDPVQKKE---EPKKAQTK-MSPK 865
Query: 607 EDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN----PN 662
D P+ P G P PP P T V + K + EQ ++ +LN +
Sbjct: 866 PDAKPM-PKG------SPTPPGPRPTAGQTVPTPQQSPKPQ----EQSRRFSLNLGSITD 914
Query: 663 AKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPA 722
A + PT P +V T G S S + TAGQ G +S P
Sbjct: 915 APKSQPTTPQETV---TGKLFGFGASIFSQASNLISTAGQPGPHSQSGPG-------APM 964
Query: 723 VQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPAS---------APPMMQAAAA 773
QAP P S P G+ A P + + PA+ AP + +
Sbjct: 965 KQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETE 1024
Query: 774 AGPPLV------AATPYSSYIPYNPQQFP 796
PP + A P + +P ++ P
Sbjct: 1025 KKPPPIKDSKSLTAEPQKAVLPTKLEKSP 1053
Score = 51.2 bits (121), Expect = 5e-06
Identities = 42/119 (35%), Positives = 53/119 (44%), Gaps = 17/119 (14%)
Query: 6 PLQQPSQPQQPPPTQQAVARRP----PGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61
P QQP + PPTQQ +P PG SP PGP T PGP + GP
Sbjct: 401 PAQQPGPAK--PPTQQVGTPKPLAQQPGLQSPAKA--PGPTKTPVQQPGPGKIPAQQAGP 456
Query: 62 --VAAAGSGLRRGAEGILAPQPPPPQQ------HQERPGAAAIGSARGQSTGKGPPQSP 112
+A +G + + P PPPQQ ++PG+A S + ST K PPQ P
Sbjct: 457 GKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGST-KPPPQQP 514
Score = 44.7 bits (104), Expect = 5e-04
Identities = 39/119 (32%), Positives = 45/119 (37%), Gaps = 30/119 (25%)
Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTSPP--NGGLPGPLA----TSAAPPGPPAAASPCL 59
P+QQP+ P +PP Q + PG PP GL PLA T P PP P
Sbjct: 305 PIQQPT-PGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA 363
Query: 60 GPVAAAGSGLRRGAEGILAPQPPPPQQ------HQERPGAAAIGSARGQSTGKGPPQSP 112
P L P PP QQ E+PG A+ G GK P Q P
Sbjct: 364 QP---------------LGPAKPPAQQTGSEKPSSEQPGPKALAQPPG--VGKTPAQQP 405
Score = 39.3 bits (90), Expect = 0.020
Identities = 34/101 (33%), Positives = 41/101 (40%), Gaps = 16/101 (15%)
Query: 3 KPQPLQQPSQPQQPPPTQQAVARRP---PGGTSPPNGGLPGPLATSAAPPGPPAAASPCL 59
KP P QQP P +PPP Q A+ P PG T PP PGP S PG + P
Sbjct: 478 KPPP-QQPG-PAKPPPQQPGSAKPPSQQPGSTKPPPQQ-PGPAKPSPQQPG--STKPPSQ 532
Query: 60 GPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSAR 100
P +A S + P P P Q + GS +
Sbjct: 533 QPGSAKPSAQQ--------PSPAKPSAQQSTKPVSQTGSGK 565
Score = 37.7 bits (86), Expect = 0.057
Identities = 31/83 (37%), Positives = 38/83 (45%), Gaps = 8/83 (9%)
Query: 6 PLQQPSQPQQPPPTQQAVAR---RPPGGTSPPNGGLPGPLATSAAPPGP-PAAASPCLGP 61
P QQP + PPP Q A+ + PG T PP+ PG SA P P +A P
Sbjct: 500 PSQQPGSTK-PPPQQPGPAKPSPQQPGSTKPPS-QQPGSAKPSAQQPSPAKPSAQQSTKP 557
Query: 62 VAAAGSG--LRRGAEGILAPQPP 82
V+ GSG L+ A QPP
Sbjct: 558 VSQTGSGKPLQPPTVSPSAKQPP 580
Score = 36.6 bits (83), Expect = 0.13
Identities = 36/112 (32%), Positives = 45/112 (40%), Gaps = 13/112 (11%)
Query: 6 PLQQPSQ---PQQPPPTQQAVARRPP--GGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
P + PSQ P +PPP Q A+ PP G++ P PG PG PA SP
Sbjct: 466 PTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPG-PAKPSP-QQ 523
Query: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112
P + + G+ A QP P +P A Q TG G P P
Sbjct: 524 PGSTKPPSQQPGSAKPSAQQPSP-----AKPSAQQSTKPVSQ-TGSGKPLQP 569
Score = 36.2 bits (82), Expect = 0.17
Identities = 64/256 (25%), Positives = 79/256 (30%), Gaps = 52/256 (20%)
Query: 792 PQQFPGQPAMMQPMAHYPSQ--PVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPT 849
P+ P QP P Q P P+ Q S P+ I S Q P +P
Sbjct: 203 PEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKS----QPPGTGKPI 258
Query: 850 --PQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSG 907
P T H P Q A +PQ + + PSP + P +
Sbjct: 259 QGPTQTPQTDHAKLP---LQRDASRPQTKQADIVRGESVKPSLPSPSK------PPIQQP 309
Query: 908 QPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAH 967
P G PP+ PG P + P PA P G T
Sbjct: 310 TP-----------GKPPAQQPGHEKSQPGPAKP-PAQ---------PSGLTK-----PLA 343
Query: 968 VQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHP 1027
Q G P PG PP L GP + Q+G S+ P P P
Sbjct: 344 QQPGTVKPPVQPPGTTKPPAQPL--------GPAKPPAQQTGSEKPSSEQPGPKALAQPP 395
Query: 1028 QVQSHPSQQL-PFHPP 1042
V P+QQ P PP
Sbjct: 396 GVGKTPAQQPGPAKPP 411
Score = 35.4 bits (80), Expect = 0.28
Identities = 34/114 (29%), Positives = 46/114 (40%), Gaps = 12/114 (10%)
Query: 4 PQPLQQPSQPQQPP--PTQQA----VARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASP 57
P P + P Q P P QQA + + G T PP+ LPGP PGP A P
Sbjct: 434 PGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQ-LPGPAKPPPQQPGP--AKPP 490
Query: 58 CLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS 111
P +A + G+ QP P + ++PG+ S Q G P +
Sbjct: 491 PQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPS---QQPGSAKPSA 541
Score = 35.4 bits (80), Expect = 0.28
Identities = 61/265 (23%), Positives = 101/265 (38%), Gaps = 51/265 (19%)
Query: 390 SSPGPGSEARGINGGPSRMSP--KAQRPLRGAKTLS-SPSNRPSGETSVPPP---PAVGR 443
S PGP SE++G ++ P K + P + +S P +P + S PP P G+
Sbjct: 832 SHPGPSSESKG----QKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQ 887
Query: 444 MYPP--RSPK-------------SAAPAPISA-SCPEPPIGSAVPTSSASI-----PVTS 482
P +SPK S AP S + P+ + + ASI + S
Sbjct: 888 TVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIS 947
Query: 483 SVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQL 542
+ PG S S + AP + +++ P ++ G+ P K +
Sbjct: 948 TAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKS---------TGQAPPAP--AKSIPV 996
Query: 543 EELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGL--LTSEPMGSPVSSKT 600
++ K A KL+P + P + + E + K + LT+EP + + +K
Sbjct: 997 KKETKAPAAEKLEPKAEQA-------PTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKL 1049
Query: 601 ESVSDKEDKPPLAPSGGTEGPEQPP 625
E E PL + G + PP
Sbjct: 1050 EKSPKPESTCPLCKTELNIGSKDPP 1074
Score = 34.7 bits (78), Expect = 0.48
Identities = 37/128 (28%), Positives = 47/128 (36%), Gaps = 28/128 (21%)
Query: 3 KPQPLQQPSQP--------QQP----PPTQQAVARRPP----GGTSPPNGGLPGPLATSA 46
+P P + P+QP QQP PP Q +PP G PP G S+
Sbjct: 325 QPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPP-AQQTGSEKPSS 383
Query: 47 APPGPPAAAS-PCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTG 105
PGP A A P +G A G P PP QQ A + +
Sbjct: 384 EQPGPKALAQPPGVGKTPAQQPG----------PAKPPTQQVGTPKPLAQQPGLQSPAKA 433
Query: 106 KGPPQSPV 113
GP ++PV
Sbjct: 434 PGPTKTPV 441
Score = 31.2 bits (69), Expect = 5.3
Identities = 36/138 (26%), Positives = 48/138 (34%), Gaps = 15/138 (10%)
Query: 575 EPKGKEKEVDGLLTSEPMGSPV---------SSKTESVSDKEDKPPLAPSGGTEGPEQPP 625
E G+EK L + P S + SS + + PP P P PP
Sbjct: 2365 ETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPP 2424
Query: 626 PPCPSQTGSPPVGLIKGEDKDEGPVAEQV----KKSTLNPNAKEFNPTKPLLSVNKSTST 681
PP P T P L K + PV +TL A + P+ + T+
Sbjct: 2425 PPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRI--CTTA 2482
Query: 682 PTSPGPRTHSTPSIPVLT 699
P P+ S PS V T
Sbjct: 2483 PPPVPPKPSSIPSGLVFT 2500
Score = 30.4 bits (67), Expect = 9.1
Identities = 28/122 (22%), Positives = 53/122 (43%), Gaps = 11/122 (9%)
Query: 533 LQNEQKRFQLEELRKFGAQFKLQP---SSSPENSLDPFPPRILKEEPKGKEKEVDGLLTS 589
+++E+K+ LEE + KL P +S+PE +LK + + E++++G +
Sbjct: 1227 IRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHD----LLKSQVQIAEEKLEGRVAP 1282
Query: 590 EPMGSPVSSKTESVSDKEDKPPLAPSGGTEGP----EQPPPPCPSQTGSPPVGLIKGEDK 645
+ + +T+ P P + EQP PPC ++ G K E +
Sbjct: 1283 KTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKE 1342
Query: 646 DE 647
D+
Sbjct: 1343 DD 1344
Score = 30.4 bits (67), Expect = 9.1
Identities = 38/155 (24%), Positives = 57/155 (36%), Gaps = 18/155 (11%)
Query: 534 QNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMG 593
+ E K+ + R G SS E L +LKE+ K +E E
Sbjct: 1749 KGESKQQRKARHRPHGPLLPTIEDSSEEEELRE-EEELLKEQEKQREIEQQ--------- 1798
Query: 594 SPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPP-CPSQTGSPPVGLIKGEDKDE---GP 649
K+ S K+DK L E P+ PP P + SP L + + +E
Sbjct: 1799 ---QRKSSSKKSKKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSS 1855
Query: 650 VAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTS 684
+E +P E +P K ++ V K PT+
Sbjct: 1856 CSEYSPSIESDPEGFEISPEK-IIEVQKVYKLPTA 1889
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 75.9 bits (185), Expect = 2e-13
Identities = 163/679 (24%), Positives = 235/679 (34%), Gaps = 159/679 (23%)
Query: 375 GLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETS 434
GL++ G SP + G+ S++S + +R + A +S P G S
Sbjct: 15 GLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQI--AAVMSRAQGLPKG--S 70
Query: 435 VPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISP 494
VPP A SP + +S P P S P DPG P
Sbjct: 71 VPPAAA-------ESPSMHRKQELDSSHP--------PKQSGRPP------DPG----RP 105
Query: 495 ASPKISLA-PTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKF----G 549
A P +S + TD K PGR+ P ++ L+ + R L+E K G
Sbjct: 106 AQPGLSKSRTTDTFRSEQKLPGRS--PSTIS--------LKESKSRTDLKEEHKSSMMPG 155
Query: 550 AQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKED- 608
++ S+ + ++ F P L + + ++E ++K + V KE
Sbjct: 156 FLSEVNALSAVSSVVNKFNPFDLISDSEASQEE--------------TTKKQKVVQKEQG 201
Query: 609 ------KPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPN 662
KPPL +QPP P P Q G G D P+ + +++
Sbjct: 202 KPEGIIKPPLQ--------QQPPKPIPKQQG-------PGRD----PLQQDGTPKSISSQ 242
Query: 663 AKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPA 722
E ++P K PT H+ +P+ Q + PQ
Sbjct: 243 QPEKIKSQP-PGTGKPIQGPTQTPQTDHA--KLPL-----------QRDASRPQTKQADI 288
Query: 723 VQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAAT 782
V+ + P S S P Q G + P ++ QP A P Q + P +A
Sbjct: 289 VRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGH-EKSQPGPAKPPAQPSGLTKP--LAQQ 345
Query: 783 PYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQY 842
P + P P PG ++P P+ + P +GS +
Sbjct: 346 PGTVKPPVQP---PG-----------TTKPPAQPLGPAKPPAQQTGS-----------EK 380
Query: 843 PSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAG-QA 901
PS+EQP P+AL + P + A QP PA PT Q P P+ Q G Q+
Sbjct: 381 PSSEQPGPKAL------AQPPGVGKTPAQQPGPAKPPT-----QQVGTPKPLAQQPGLQS 429
Query: 902 PHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMA 961
P G + + PG G P+ GP S Q + P QLP
Sbjct: 430 PAKAPGPTKTPVQQPG--PGKIPAQQAGPGKTSAQQTGPTKPP------SQLP------G 475
Query: 962 HVTQAHVQTGITAAPPPHPGAPHPP--QVMLLHPPQSHGGPPQGAVPQSGVPALSASTPS 1019
Q G PP PG+ PP Q PP GP + + Q G S PS
Sbjct: 476 PAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPG----STKPPS 531
Query: 1020 PYPYIGHPQVQSHPSQQLP 1038
P P Q PS P
Sbjct: 532 QQPGSAKPSAQ-QPSPAKP 549
Score = 68.9 bits (167), Expect = 2e-11
Identities = 157/690 (22%), Positives = 231/690 (33%), Gaps = 123/690 (17%)
Query: 333 QGSGRESPSLASREGKYIPLPQRVREGPR---GGVRCSSSRGG-------RPGLSSLPPR 382
Q +G E PS K + P V + P G + + + G +PGL S P +
Sbjct: 374 QQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQS-PAK 432
Query: 383 --GPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGET--SVPPP 438
GP PGPG + GP + S + P + L P+ P + + PPP
Sbjct: 433 APGPTKTPVQQPGPG-KIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPP 491
Query: 439 PAVGRMYPP-----------RSPKSAAPAPISASCPEPPI---GSAVPTSSASIPV---- 480
G PP + P A P+P +PP GSA P++ P
Sbjct: 492 QQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSA 551
Query: 481 ---TSSVSDPGVG------SISPAS--------PK--ISLAPTDVKELSTKEPGRTLEPQ 521
T VS G G ++SP++ PK L T L E
Sbjct: 552 QQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCT 611
Query: 522 ELARIAGKVPGLQNEQKRFQLEELRKFGAQFK------LQP-SSSPENSLDPFP----PR 570
E + G +++E Q K L P SSP+ L P
Sbjct: 612 ECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSA 671
Query: 571 ILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEG-----PEQPP 625
+ K P+ ++ TS + + + PPL G +QPP
Sbjct: 672 VSKSSPQPQQ-------TSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPP 724
Query: 626 PPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSP 685
+PP ++D+ PVA+ K K PT L+S + +T+ P P
Sbjct: 725 EADSLSKPAPPKEPSVPSEQDKAPVADDKPK-----QPKMVKPTTDLVSSSSATTKPDIP 779
Query: 686 GPRTHS------TPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPG 739
+ S TP + +A S + P P A+ P +S+ PG
Sbjct: 780 SSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSP--FDSKAIPRPASDSKIISH--PG 835
Query: 740 QQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQP 799
+ +G K P Q+ + +P A M A P P S P P+ GQ
Sbjct: 836 PSSESKGQKQVDPVQKKE--EPKKAQTKMSPKPDAKP-----MPKGSPTPPGPRPTAGQT 888
Query: 800 AMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQ 859
+ P + QS L GS ++ + P+ Q T
Sbjct: 889 VPTPQQSPKPQE-------QSRRFSLNLGS-----ITDAPKSQPTTPQETVTGKLFGFGA 936
Query: 860 SYPHHATQL--HAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPG 917
S A+ L A QP P + P Q AP+P Q Q P +GQ
Sbjct: 937 SIFSQASNLISTAGQPGPHSQSGPGAPMKQ--APAPSQPPTSQGPPKSTGQ--------- 985
Query: 918 ALTGTPPSLPPGPSAQSPQSSFPQPAAVYA 947
A S+P ++P + +P A A
Sbjct: 986 APPAPAKSIPVKKETKAPAAEKLEPKAEQA 1015
Score = 59.3 bits (142), Expect = 2e-08
Identities = 145/670 (21%), Positives = 207/670 (30%), Gaps = 132/670 (19%)
Query: 405 PSRMSPKAQRPLRG-----AKTLSSPSNRPSGETSVPP---PPAVGRMYPPRSPKSAAPA 456
P + PK Q P R S S +P S PP P G P++ + P
Sbjct: 215 PPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPL 274
Query: 457 PISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGR 516
AS P+ V S P S S P + +P P + + +P
Sbjct: 275 QRDASRPQTKQADIVRGESVK-PSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKP-- 331
Query: 517 TLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEP 576
+P L + + PG + Q K AQ L P+ P P + P
Sbjct: 332 PAQPSGLTKPLAQQPG--TVKPPVQPPGTTKPPAQ-PLGPAKPPAQQTGSEKPSSEQPGP 388
Query: 577 KGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPP 636
K + T P T+ V + PLA G + P + P P + P
Sbjct: 389 KALAQPPGVGKTPAQQPGPAKPPTQQVGTPK---PLAQQPGLQSPAKAPGPTKTPVQQPG 445
Query: 637 VGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIP 696
G I + G +A++ PTKP + PGP
Sbjct: 446 PGKIPAQQAGPG-----------KTSAQQTGPTKPPSQL---------PGP--------- 476
Query: 697 VLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRS 756
+ P GPA PQ P S P QQ GS P
Sbjct: 477 ---------------AKPPPQQPGPAKPPPQQ---PGSAKPPSQQ------PGSTKP--- 509
Query: 757 DQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAP 816
QP A P Q + PP QP +P A PS +
Sbjct: 510 PPQQPGPAKPSPQQPGSTKPP------------------SQQPGSAKPSAQQPSPAKPSA 551
Query: 817 MLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPA 876
+ P T P + S PSA+QP Q L T+ + T+L H P+ A
Sbjct: 552 QQSTKPVSQTGSGKPLQPPTVS----PSAKQPPSQGLPKTICPLC--NTTELLLHVPEKA 605
Query: 877 TTPTGSQPQSQHAA-----PSPVQHQAGQ----------------APHLGSGQPQQNLYH 915
T ++ Q+ + P+P + + AP S QP+
Sbjct: 606 NFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKT-A 664
Query: 916 PGALTGTPPSLPPGPSAQSPQ---------SSFPQPAAVYAIHHQQLPHGFTNMAHVTQA 966
P T P P SP+ S P+P + Q HG +
Sbjct: 665 PVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPP 724
Query: 967 HVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGH 1026
+ APP P P P + P Q + + +S+S+ + P I
Sbjct: 725 EADSLSKPAPPKEPSVPSEQD----KAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPS 780
Query: 1027 PQVQSHPSQQ 1036
+VQS ++
Sbjct: 781 SKVQSQAEEK 790
Score = 55.1 bits (131), Expect = 3e-07
Identities = 99/449 (22%), Positives = 159/449 (35%), Gaps = 78/449 (17%)
Query: 373 RPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGE 432
+P L + P + SSP P + + P + KA P + + P+ S
Sbjct: 658 QPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPS 717
Query: 433 TSVPPPPAVGRMYPPRSPKSAA------PAPISASCPEPPIGSAVPTSSASIPVTSSVSD 486
PP + P PK + AP++ P+ P V ++ + +S+ +
Sbjct: 718 AKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQP--KMVKPTTDLVSSSSATTK 775
Query: 487 PGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELR 546
P + S S +K S K P ++ P E++
Sbjct: 776 PDIPSSKVQSQAEEKTTPPLKTDSAK-PSQSFPPTG--------------------EKVS 814
Query: 547 KFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDK 606
F ++ +P+S + P P E KG +K+VD + E P ++T+ +S K
Sbjct: 815 PFDSKAIPRPASDSKIISHPGP----SSESKG-QKQVDPVQKKE---EPKKAQTK-MSPK 865
Query: 607 EDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN----PN 662
D P+ P G P PP P T V + K + EQ ++ +LN +
Sbjct: 866 PDAKPM-PKG------SPTPPGPRPTAGQTVPTPQQSPKPQ----EQSRRFSLNLGSITD 914
Query: 663 AKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPA 722
A + PT P +V T G S S + TAGQ G +S P
Sbjct: 915 APKSQPTTPQETV---TGKLFGFGASIFSQASNLISTAGQPGPHSQSGPG-------APM 964
Query: 723 VQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPAS---------APPMMQAAAA 773
QAP P S P G+ A P + + PA+ AP + +
Sbjct: 965 KQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETE 1024
Query: 774 AGPPLV------AATPYSSYIPYNPQQFP 796
PP + A P + +P ++ P
Sbjct: 1025 KKPPPIKDSKSLTAEPQKAVLPTKLEKSP 1053
Score = 51.2 bits (121), Expect = 5e-06
Identities = 42/119 (35%), Positives = 53/119 (44%), Gaps = 17/119 (14%)
Query: 6 PLQQPSQPQQPPPTQQAVARRP----PGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61
P QQP + PPTQQ +P PG SP PGP T PGP + GP
Sbjct: 401 PAQQPGPAK--PPTQQVGTPKPLAQQPGLQSPAKA--PGPTKTPVQQPGPGKIPAQQAGP 456
Query: 62 --VAAAGSGLRRGAEGILAPQPPPPQQ------HQERPGAAAIGSARGQSTGKGPPQSP 112
+A +G + + P PPPQQ ++PG+A S + ST K PPQ P
Sbjct: 457 GKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGST-KPPPQQP 514
Score = 44.7 bits (104), Expect = 5e-04
Identities = 39/119 (32%), Positives = 45/119 (37%), Gaps = 30/119 (25%)
Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTSPP--NGGLPGPLA----TSAAPPGPPAAASPCL 59
P+QQP+ P +PP Q + PG PP GL PLA T P PP P
Sbjct: 305 PIQQPT-PGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA 363
Query: 60 GPVAAAGSGLRRGAEGILAPQPPPPQQ------HQERPGAAAIGSARGQSTGKGPPQSP 112
P L P PP QQ E+PG A+ G GK P Q P
Sbjct: 364 QP---------------LGPAKPPAQQTGSEKPSSEQPGPKALAQPPG--VGKTPAQQP 405
Score = 39.3 bits (90), Expect = 0.020
Identities = 34/101 (33%), Positives = 41/101 (40%), Gaps = 16/101 (15%)
Query: 3 KPQPLQQPSQPQQPPPTQQAVARRP---PGGTSPPNGGLPGPLATSAAPPGPPAAASPCL 59
KP P QQP P +PPP Q A+ P PG T PP PGP S PG + P
Sbjct: 478 KPPP-QQPG-PAKPPPQQPGSAKPPSQQPGSTKPPPQQ-PGPAKPSPQQPG--STKPPSQ 532
Query: 60 GPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSAR 100
P +A S + P P P Q + GS +
Sbjct: 533 QPGSAKPSAQQ--------PSPAKPSAQQSTKPVSQTGSGK 565
Score = 37.7 bits (86), Expect = 0.057
Identities = 31/83 (37%), Positives = 38/83 (45%), Gaps = 8/83 (9%)
Query: 6 PLQQPSQPQQPPPTQQAVAR---RPPGGTSPPNGGLPGPLATSAAPPGP-PAAASPCLGP 61
P QQP + PPP Q A+ + PG T PP+ PG SA P P +A P
Sbjct: 500 PSQQPGSTK-PPPQQPGPAKPSPQQPGSTKPPS-QQPGSAKPSAQQPSPAKPSAQQSTKP 557
Query: 62 VAAAGSG--LRRGAEGILAPQPP 82
V+ GSG L+ A QPP
Sbjct: 558 VSQTGSGKPLQPPTVSPSAKQPP 580
Score = 36.6 bits (83), Expect = 0.13
Identities = 36/112 (32%), Positives = 45/112 (40%), Gaps = 13/112 (11%)
Query: 6 PLQQPSQ---PQQPPPTQQAVARRPP--GGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
P + PSQ P +PPP Q A+ PP G++ P PG PG PA SP
Sbjct: 466 PTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPG-PAKPSP-QQ 523
Query: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112
P + + G+ A QP P +P A Q TG G P P
Sbjct: 524 PGSTKPPSQQPGSAKPSAQQPSP-----AKPSAQQSTKPVSQ-TGSGKPLQP 569
Score = 36.2 bits (82), Expect = 0.17
Identities = 64/256 (25%), Positives = 79/256 (30%), Gaps = 52/256 (20%)
Query: 792 PQQFPGQPAMMQPMAHYPSQ--PVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPT 849
P+ P QP P Q P P+ Q S P+ I S Q P +P
Sbjct: 203 PEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKS----QPPGTGKPI 258
Query: 850 --PQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSG 907
P T H P Q A +PQ + + PSP + P +
Sbjct: 259 QGPTQTPQTDHAKLP---LQRDASRPQTKQADIVRGESVKPSLPSPSK------PPIQQP 309
Query: 908 QPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAH 967
P G PP+ PG P + P PA P G T
Sbjct: 310 TP-----------GKPPAQQPGHEKSQPGPAKP-PAQ---------PSGLTK-----PLA 343
Query: 968 VQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHP 1027
Q G P PG PP L GP + Q+G S+ P P P
Sbjct: 344 QQPGTVKPPVQPPGTTKPPAQPL--------GPAKPPAQQTGSEKPSSEQPGPKALAQPP 395
Query: 1028 QVQSHPSQQL-PFHPP 1042
V P+QQ P PP
Sbjct: 396 GVGKTPAQQPGPAKPP 411
Score = 35.4 bits (80), Expect = 0.28
Identities = 34/114 (29%), Positives = 46/114 (40%), Gaps = 12/114 (10%)
Query: 4 PQPLQQPSQPQQPP--PTQQA----VARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASP 57
P P + P Q P P QQA + + G T PP+ LPGP PGP A P
Sbjct: 434 PGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQ-LPGPAKPPPQQPGP--AKPP 490
Query: 58 CLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS 111
P +A + G+ QP P + ++PG+ S Q G P +
Sbjct: 491 PQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPS---QQPGSAKPSA 541
Score = 35.4 bits (80), Expect = 0.28
Identities = 61/265 (23%), Positives = 101/265 (38%), Gaps = 51/265 (19%)
Query: 390 SSPGPGSEARGINGGPSRMSP--KAQRPLRGAKTLS-SPSNRPSGETSVPPP---PAVGR 443
S PGP SE++G ++ P K + P + +S P +P + S PP P G+
Sbjct: 832 SHPGPSSESKG----QKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQ 887
Query: 444 MYPP--RSPK-------------SAAPAPISA-SCPEPPIGSAVPTSSASI-----PVTS 482
P +SPK S AP S + P+ + + ASI + S
Sbjct: 888 TVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIS 947
Query: 483 SVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQL 542
+ PG S S + AP + +++ P ++ G+ P K +
Sbjct: 948 TAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKS---------TGQAPPAP--AKSIPV 996
Query: 543 EELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGL--LTSEPMGSPVSSKT 600
++ K A KL+P + P + + E + K + LT+EP + + +K
Sbjct: 997 KKETKAPAAEKLEPKAEQA-------PTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKL 1049
Query: 601 ESVSDKEDKPPLAPSGGTEGPEQPP 625
E E PL + G + PP
Sbjct: 1050 EKSPKPESTCPLCKTELNIGSKDPP 1074
Score = 34.7 bits (78), Expect = 0.48
Identities = 37/128 (28%), Positives = 47/128 (36%), Gaps = 28/128 (21%)
Query: 3 KPQPLQQPSQP--------QQP----PPTQQAVARRPP----GGTSPPNGGLPGPLATSA 46
+P P + P+QP QQP PP Q +PP G PP G S+
Sbjct: 325 QPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPP-AQQTGSEKPSS 383
Query: 47 APPGPPAAAS-PCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTG 105
PGP A A P +G A G P PP QQ A + +
Sbjct: 384 EQPGPKALAQPPGVGKTPAQQPG----------PAKPPTQQVGTPKPLAQQPGLQSPAKA 433
Query: 106 KGPPQSPV 113
GP ++PV
Sbjct: 434 PGPTKTPV 441
Score = 31.2 bits (69), Expect = 5.3
Identities = 36/138 (26%), Positives = 48/138 (34%), Gaps = 15/138 (10%)
Query: 575 EPKGKEKEVDGLLTSEPMGSPV---------SSKTESVSDKEDKPPLAPSGGTEGPEQPP 625
E G+EK L + P S + SS + + PP P P PP
Sbjct: 2365 ETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPP 2424
Query: 626 PPCPSQTGSPPVGLIKGEDKDEGPVAEQV----KKSTLNPNAKEFNPTKPLLSVNKSTST 681
PP P T P L K + PV +TL A + P+ + T+
Sbjct: 2425 PPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRI--CTTA 2482
Query: 682 PTSPGPRTHSTPSIPVLT 699
P P+ S PS V T
Sbjct: 2483 PPPVPPKPSSIPSGLVFT 2500
Score = 30.4 bits (67), Expect = 9.1
Identities = 28/122 (22%), Positives = 53/122 (43%), Gaps = 11/122 (9%)
Query: 533 LQNEQKRFQLEELRKFGAQFKLQP---SSSPENSLDPFPPRILKEEPKGKEKEVDGLLTS 589
+++E+K+ LEE + KL P +S+PE +LK + + E++++G +
Sbjct: 1227 IRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHD----LLKSQVQIAEEKLEGRVAP 1282
Query: 590 EPMGSPVSSKTESVSDKEDKPPLAPSGGTEGP----EQPPPPCPSQTGSPPVGLIKGEDK 645
+ + +T+ P P + EQP PPC ++ G K E +
Sbjct: 1283 KTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKE 1342
Query: 646 DE 647
D+
Sbjct: 1343 DD 1344
Score = 30.4 bits (67), Expect = 9.1
Identities = 38/155 (24%), Positives = 57/155 (36%), Gaps = 18/155 (11%)
Query: 534 QNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMG 593
+ E K+ + R G SS E L +LKE+ K +E E
Sbjct: 1749 KGESKQQRKARHRPHGPLLPTIEDSSEEEELRE-EEELLKEQEKQREIEQQ--------- 1798
Query: 594 SPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPP-CPSQTGSPPVGLIKGEDKDE---GP 649
K+ S K+DK L E P+ PP P + SP L + + +E
Sbjct: 1799 ---QRKSSSKKSKKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSS 1855
Query: 650 VAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTS 684
+E +P E +P K ++ V K PT+
Sbjct: 1856 CSEYSPSIESDPEGFEISPEK-IIEVQKVYKLPTA 1889
>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
Length = 2217
Score = 75.1 bits (183), Expect = 3e-13
Identities = 117/444 (26%), Positives = 154/444 (34%), Gaps = 76/444 (17%)
Query: 621 PEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTS 680
P PPP P TG G+ G + + T P P PL V
Sbjct: 708 PVLPPPSTPMPTGP-------GQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPV----- 755
Query: 681 TPTSPGPRTHSTPSIPVLTAGQSGLYSPQYIS--YIPQIHMGPAVQAP-QMYPYPVSNSV 737
P +P A S + +P + +PQ + P Q P QM P PV +
Sbjct: 756 -----------PPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPI 804
Query: 738 PGQQGKYRGAKGSLPPQRSDQHQ---PASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQ 794
G LPP D P PP + A P L A P +S P P Q
Sbjct: 805 TPLAGI-----DGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPAS--PALPLQ 857
Query: 795 F------PGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVS-SSTPQYPSAEQ 847
PG P M P+ P P+L P + + S A+ P YP+A
Sbjct: 858 AVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAA-- 915
Query: 848 PTPQALYATVHQSYPHHATQ-LHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGS 906
PQ V S PHH Q + A PQPA P + P P P P +
Sbjct: 916 -FPQMAPTDVPPS-PHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPT 973
Query: 907 GQPQQNLYHPGALTGTPPSLPPGPS----AQSPQSSFPQPAAVYAIHHQQLPHGFTNMAH 962
+P Q + P + P LPP P+ + Q P+ AA A Q+ G +
Sbjct: 974 -RPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHP-APY 1031
Query: 963 VTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQ--SGVPALSASTPSP 1020
Q PP +P P+V+L P+ +PQ S + +SAS
Sbjct: 1032 AVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPE--------LLPQFPSSLATVSAS---- 1079
Query: 1021 YPYIGHPQVQSHPSQQLPFHPPGN 1044
VQS P+Q PP N
Sbjct: 1080 --------VQSVPTQTATLLPPAN 1095
Score = 49.3 bits (116), Expect = 2e-05
Identities = 77/274 (28%), Positives = 91/274 (33%), Gaps = 48/274 (17%)
Query: 770 AAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGS 829
A AA P +P S P PQ P A QP A P PV + + P L
Sbjct: 641 ADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTA-APGLPVGSVPAPACPPSLQQHF 699
Query: 830 HPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHA 889
A+ + PS PT A Q QP P PT P Q
Sbjct: 700 PDPAMSFAPVLPPPSTPMPTGPGQPAPPGQ------------QPPPLAQPT---PLPQVL 744
Query: 890 APSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIH 949
AP PV PHL P + G P L P Q+P QP A
Sbjct: 745 APQPVVPLQPVPPHL------PPYLAPASQVGAPAQLKPLQMPQAPL----QPLA----- 789
Query: 950 HQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSG 1009
Q+P + V GI PP P P PP PPQ P
Sbjct: 790 --QVPPQMPPIPVVPPITPLAGIDGLPPALPDLP-----TATVPPVP---PPQYFSPAVI 839
Query: 1010 VPALSASTPSPYPYIGHPQVQSHPSQQLPFHPPG 1043
+P+L+A P P + V +LP HPPG
Sbjct: 840 LPSLAAPLPPASPALPLQAV------KLP-HPPG 866
Score = 45.4 bits (106), Expect = 3e-04
Identities = 53/179 (29%), Positives = 70/179 (39%), Gaps = 21/179 (11%)
Query: 352 LPQRVREGPRG----GVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSR 407
+P + E RG G+ ++ RPG R D P PG EA G P
Sbjct: 10 VPGTLMEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEP-PGLEAAEAPG-PQP 67
Query: 408 MSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPA-VGRMYPPRSPKSAAPAPISASCPEP- 465
P +R L KT + R G + P P A V + P +P A P P+ P P
Sbjct: 68 PQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVGTQEPGPD 127
Query: 466 PIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTL--EPQE 522
PI +AV T+ A P G A+ + E + EPGRT EP+E
Sbjct: 128 PIAAAVETAPA----------PDGGPREEAAATVRKEDEGAAE-AKPEPGRTRRDEPEE 175
Score = 42.4 bits (98), Expect = 0.002
Identities = 78/303 (25%), Positives = 108/303 (35%), Gaps = 46/303 (15%)
Query: 736 SVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSY-IPYNPQQ 794
S PG + G + S Q Q A+AP Q G P + + P P+
Sbjct: 1271 SDPGTSPPHLSTCGLGTGEESRQSQ-ANAPVYQQNVLHTGKRWFIICPVAEHPAPEAPES 1329
Query: 795 FPGQP-AMMQPMAHYPSQPVFAPMLQSN--PRMLTSGSHPQAIVSSSTPQYPSAEQPTPQ 851
P P + + P A S P + L S P L S Q ++S + P P P P
Sbjct: 1330 SPPLPLSSLPPEASQDSAP-YKDQLSSKEQPSFLAS----QQLLSQAGPSNPPGAPPAPL 1384
Query: 852 ALYATVHQSYPHH-ATQLHAHQPQPAT----------TPTG-------SQPQSQ-HAAPS 892
A + + P A + P+PA+ TP G SQP ++ H AP
Sbjct: 1385 APSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAPL 1444
Query: 893 PVQHQA-GQAPHLGSGQPQQNLYHPGALTGTPPSLP-PGPSAQSPQSSFPQPAAVYAIHH 950
VQ G AP + + PP P P P + +PQ + QPA +
Sbjct: 1445 AVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPL----- 1499
Query: 951 QQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGV 1010
LP A V + T +PP P P P L G PP+ S +
Sbjct: 1500 --LP------AAVGAVSLATSQLPSPPLGPTVPPQPPSAL--ESDGEGPPPRVGFVDSTI 1549
Query: 1011 PAL 1013
+L
Sbjct: 1550 KSL 1552
Score = 42.0 bits (97), Expect = 0.003
Identities = 179/825 (21%), Positives = 273/825 (33%), Gaps = 171/825 (20%)
Query: 1 MLKPQPL--QQPSQPQQPPPTQQAVARRPPGGTSPPNG---GLPGPLATSAAP-----PG 50
ML PQP+ QP+ P +P P Q + + +P + G P P A A P
Sbjct: 985 MLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPV 1044
Query: 51 PPAA------------ASPCLGP--------VAAAGSGLRRGAEGILAPQPPPPQQHQER 90
PPAA A+P L P V+A+ + +L P PP
Sbjct: 1045 PPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPP------L 1098
Query: 91 PGAAAIGSA------------RGQSTGKGPPQSPVFEGVYNNSRMLHFLTAVVGSTCDVK 138
PG I S Q++ PP P Y S + + +C+
Sbjct: 1099 PGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGGSDVTS--GKELSDSCE-- 1154
Query: 139 VKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRRE-----DIVDTMV---FKPSDV 190
G G + +++ R E A PR + D MV + +
Sbjct: 1155 ---GAFGGGRLEGRAARKHHRRSTRARSRQERASRPRLTILNVCNTGDKMVECQLETHNH 1211
Query: 191 MLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDDYDLESDMSNG 250
+V F+ D + D+ + + + E + + Q + D D ++D G
Sbjct: 1212 KMVTFK-FDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDMLSEDTDADRG 1270
Query: 251 WDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLAREI-----ES 305
DP + G+ T +S S P+ + N +R +A ES
Sbjct: 1271 SDPGTSPP-HLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAPEAPES 1329
Query: 306 SPQYRLRIAMENDDGRTEEEKHSAVQR-QGSGRESPS-LASREGKYIPLPQRVREGPRGG 363
SP L E + SA + Q S +E PS LAS++ P P
Sbjct: 1330 SPPLPLSSLPP------EASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAP 1383
Query: 364 VRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGP------------------ 405
+ SS P +++LP G ++ P P S GGP
Sbjct: 1384 LAPSS-----PPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAE 1438
Query: 406 SRMSPKAQRPLRG--AKTLSSPSNRPSGETSVP----PPPAVGRMYPPRSPKSAAPAPI- 458
+ +P A +PL A +P + + S P PPPA P SP S P P
Sbjct: 1439 THEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPA-----PEPSPHSGTPQPAL 1493
Query: 459 -----------------SASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISL 501
++ P PP+G VP S + P P++
Sbjct: 1494 GQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPP---------PRVGF 1544
Query: 502 APTDVKELSTKEPGRTLEPQELARIAGKVPGLQNE--QKRFQLEELRKFGAQFKLQPSSS 559
+ +K L K RTL QE + G E + F LE LR G Q + +
Sbjct: 1545 VDSTIKSLDEKL--RTLLYQEHVPTSSASAGTPVEVGDRDFTLEPLR--GDQPRSEVCGG 1600
Query: 560 PENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTE 619
+ +L P P + + + V+ + G+ + T S E P +
Sbjct: 1601 -DLALPPVPKEAVSGRVQLPQPLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRD 1659
Query: 620 GPE--QPPPPCPSQTGSPPV----GLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLL 673
G + PS P ++ D+D G E S+ P P +
Sbjct: 1660 GRQVASDSHVVPSVPQDVPAFVRPARVEPTDRDGGEAGE----SSAEP------PPSDMG 1709
Query: 674 SVNKSTSTPTSPGPRTHSTP---------SIPVLTAGQSGLYSPQ 709
+V S P + G R +P S P T G+ + S Q
Sbjct: 1710 TVGGQASHPQTLGARALGSPRKRPEQQDVSSPAKTVGRFSVVSTQ 1754
Score = 35.8 bits (81), Expect = 0.22
Identities = 39/149 (26%), Positives = 60/149 (40%), Gaps = 16/149 (10%)
Query: 376 LSSLPPRGPHHLDNSSP-GPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRP-SGET 433
L +PP P +L +S G ++ + + + + P AQ P + P P +G
Sbjct: 752 LQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGID 811
Query: 434 SVPP-----PPAVGRMYPPRSPKSAAPAPI--SASCPEPPIGSAVPTSSASIPVTSSVSD 486
+PP P A PP P+ +PA I S + P PP A+P + +P
Sbjct: 812 GLPPALPDLPTATVPPVPP--PQYFSPAVILPSLAAPLPPASPALPLQAVKLP-----HP 864
Query: 487 PGVGSISPASPKISLAPTDVKELSTKEPG 515
PG P + AP + L+ PG
Sbjct: 865 PGAPLAMPCRTIVPNAPATIPLLAVAPPG 893
Score = 35.0 bits (79), Expect = 0.37
Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 8/85 (9%)
Query: 12 QPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAA-----SPCLGPVAAAG 66
+P P P A+ +P +P + G P P+ T P P AAA +P GP A
Sbjct: 92 RPAAPAPA--ALVAQPGAPGAPADAG-PEPVGTQEPGPDPIAAAVETAPAPDGGPREEAA 148
Query: 67 SGLRRGAEGILAPQPPPPQQHQERP 91
+ +R+ EG +P P + ++ P
Sbjct: 149 ATVRKEDEGAAEAKPEPGRTRRDEP 173
Score = 33.1 bits (74), Expect = 1.4
Identities = 60/249 (24%), Positives = 90/249 (36%), Gaps = 50/249 (20%)
Query: 315 MENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGPRGG-VRCSSSRGGR 373
ME + + S G R+ +AS +PQ V R V + GG
Sbjct: 1636 MEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAFVRPARVEPTDRDGGE 1695
Query: 374 PGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGET 433
G SS P P S+ + G S GA+ L SP RP +
Sbjct: 1696 AGESSAEP------------PPSDMGTVGGQASHPQTL------GARALGSPRKRPEQQD 1737
Query: 434 SVPPPPAVGR-----------MYPPRSPKSAAPAPI----SASCPEPPIGSAVPTSSASI 478
P VGR + P S + +AP + + S P+ + +++SI
Sbjct: 1738 VSSPAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSI 1797
Query: 479 ------PVTSSVSDPGVGSISPASPKISL------APTDVKELST--KEPGR--TLEPQE 522
PV+S D G + P + SL A VK+ + + P R +L P+
Sbjct: 1798 EVGVGEPVSSDSGDEGPRARPPVQKQASLPVSGSVAGDFVKKATAFLQRPSRAGSLGPET 1857
Query: 523 LARIAGKVP 531
+R+ KVP
Sbjct: 1858 PSRVGMKVP 1866
Score = 32.7 bits (73), Expect = 1.8
Identities = 31/116 (26%), Positives = 45/116 (38%), Gaps = 13/116 (11%)
Query: 910 QQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQ---- 965
QQN+ H G + P+ ++P+SS P P + Q + + +
Sbjct: 1302 QQNVLHTGKRWFIICPVAEHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSF 1361
Query: 966 -AHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020
A Q A P PGAP P P S PP A+PQ G +++ P P
Sbjct: 1362 LASQQLLSQAGPSNPPGAPPAPLA-----PSS---PPVTALPQDGAAPATSTMPEP 1409
Score = 32.0 bits (71), Expect = 3.1
Identities = 50/200 (25%), Positives = 71/200 (35%), Gaps = 31/200 (15%)
Query: 622 EQPPPPCPSQTGSPPVGLIKGE-DKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTS 680
E P P P + P+ + E +D P +Q+ F ++ LLS ++
Sbjct: 1320 EHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSK----EQPSFLASQQLLSQAGPSN 1375
Query: 681 TPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQA-----PQMYPYPVSN 735
P +P P + S PV Q G + S +P+ G A QA PQ +
Sbjct: 1376 PPGAP-PAPLAPSSPPVTALPQDG--AAPATSTMPEPASGTASQAGGPGTPQGLTSELET 1432
Query: 736 SVP---------GQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSS 786
S P Q G P + + ASAP PP +P+S
Sbjct: 1433 SQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAP-----REPLPPPAPEPSPHSG 1487
Query: 787 YIPYNPQQFPGQPAMMQPMA 806
PQ GQPA + P A
Sbjct: 1488 ----TPQPALGQPAPLLPAA 1503
Score = 31.6 bits (70), Expect = 4.1
Identities = 20/56 (35%), Positives = 20/56 (35%)
Query: 2 LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASP 57
L PQP P P PT PP T PP LP P PP A P
Sbjct: 944 LPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALP 999
Score = 30.8 bits (68), Expect = 7.0
Identities = 29/103 (28%), Positives = 41/103 (39%), Gaps = 10/103 (9%)
Query: 405 PSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPE 464
P SP P A + P +P PP P R+ APA I
Sbjct: 831 PQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATI------ 884
Query: 465 PPIGSAVPTSSASIPVTSSVSD-PGVGSISPASPKISLAPTDV 506
P+ + P A++ + S+V+ PG A P+ +APTDV
Sbjct: 885 -PLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQ--MAPTDV 924
Score = 30.4 bits (67), Expect = 9.1
Identities = 23/74 (31%), Positives = 26/74 (35%), Gaps = 9/74 (12%)
Query: 13 PQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRG 72
P P T Q + PP PP LP PP P P L P R
Sbjct: 925 PPSPHHTVQNMRATPPQPALPPQPTLP---PQPVLPPQPTLPPQPVLPPQPT------RP 975
Query: 73 AEGILAPQPPPPQQ 86
+ +L PQP P Q
Sbjct: 976 PQPVLPPQPMLPPQ 989
Score = 30.4 bits (67), Expect = 9.1
Identities = 27/76 (35%), Positives = 29/76 (38%), Gaps = 16/76 (21%)
Query: 10 PSQPQQPP-PTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSG 68
P QP PP PT PP T PP LP P T PP P P L P
Sbjct: 939 PPQPALPPQPTLPPQPVLPPQPTLPPQPVLP-PQPT--RPPQPVLPPQPMLPP------- 988
Query: 69 LRRGAEGILAPQPPPP 84
+ +L PQP P
Sbjct: 989 -----QPVLPPQPALP 999
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 72.0 bits (175), Expect = 3e-12
Identities = 167/711 (23%), Positives = 236/711 (33%), Gaps = 113/711 (15%)
Query: 305 SSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGPRGGV 364
SSPQ R R + D + + + GS S + + + V P+GG
Sbjct: 400 SSPQPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQGG- 458
Query: 365 RCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSS 424
S RG G S+ +S + G G S K +RP + S
Sbjct: 459 ---SGRGSPSGGSTA---------EASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRTHS 506
Query: 425 PSNR----PSGETSVPPPPAVGRMYPPRSPK----SAAPAPISASCPEPPIGSAVPTSSA 476
R P G +PP P R P+ P+ + +A CP P S VP S
Sbjct: 507 LHQRGLAVPDGPLGLPPKPE--RKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLS- 563
Query: 477 SIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNE 536
PG P SP+ +L+P+ + P TL P+ LA PG
Sbjct: 564 ----------PGGSRRPPRSPERTLSPSSGYSSQSGTP--TLPPKGLAGPPAS-PGKAQP 610
Query: 537 QKRFQLEELRKFGAQFKLQPSSSPENSLDPFP-----PRIL------------------- 572
K ++ LR GA +S +S DP P P+IL
Sbjct: 611 PKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPF 670
Query: 573 ---KEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKP-----PLAPSGGTEGPEQP 624
+P+ L + PVS+ T++ P PL S + P
Sbjct: 671 SPPPSKPRSPNPAAPALAAPAVVPGPVST-TDASPQSPPTPQTTLTPLQESPVISKDQSP 729
Query: 625 PPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTL-NPNAKEFNPTKPLLSVNKSTSTPT 683
PP P PP K E E P A + + L +PN + P P + S
Sbjct: 730 PPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPN---WPPPPPPAPEEQDLSMAD 786
Query: 684 SPGPRTHSTPSIPVLTAGQSGLYSPQYIS---------YIPQIHMGPAVQAPQMYPYPV- 733
P P AG SG SP+ +S QI + P P P
Sbjct: 787 FPPPEEAFFSVASPEPAGPSG--SPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAP 844
Query: 734 SNSVPGQQGKYRG------AKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSY 787
++S PG K +KG PP R D P P ++Q P +
Sbjct: 845 ASSAPGHVAKLPQKEPVGCSKGGGPP-REDVGAPLVTPSLLQMVRLRSVGAPGGAPTPAL 903
Query: 788 IPYNPQQFPGQPAMMQPMAHYPSQPVFAPM--LQSNPRMLTSGSHPQAIVSSSTPQ-YPS 844
P PQ+ P + A+ + PV AP L + R+ +SS+ P P
Sbjct: 904 GPSAPQK-PLRRALSG-----RASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPE 957
Query: 845 AEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHL 904
AE PQ+ +T + + +L +P T Q S + + QAP
Sbjct: 958 AEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKK 1017
Query: 905 GSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPH 955
P P G PP P S+P+ + A LPH
Sbjct: 1018 SPKAPPPVARKPS--VGVPPPASP---------SYPRAEPLTAPPTNGLPH 1057
Score = 54.7 bits (130), Expect = 5e-07
Identities = 146/625 (23%), Positives = 202/625 (32%), Gaps = 113/625 (18%)
Query: 467 IGSAVPTSSASIPVTSSVSDPGV----GSISPASPKISLAPTDVKELSTKEPGRTLEPQE 522
+G + T + + S++ PG+ G P SP +S++P LS P L P
Sbjct: 306 VGRSTGTRAPPLTRPMSLAVPGLTGGAGPAEPLSPAMSISP-QATYLSKLIPHAVLPPTV 364
Query: 523 LARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKE 582
G+ LR S + SL F + +P+ +
Sbjct: 365 DVVALGRC-------------SLRTLSRCSLHSASPASVRSLGRFSS-VSSPQPRSRHPS 410
Query: 583 VDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEG-PEQ--------PPPPCPSQTG 633
+S S S VSD L+ GG+EG PE PPP S G
Sbjct: 411 -----SSSDTWSHSQSSDTIVSDGST---LSSKGGSEGQPESSTASNSVVPPPQGGSGRG 462
Query: 634 SPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTP 693
SP G AE ++ + + + L + + P P RTHS
Sbjct: 463 SP----------SGGSTAEASDTLSIRSSGQLSGRSVSLRKLKR----PPPPPRRTHSLH 508
Query: 694 SIPVLTA-GQSGLYSPQYISYIPQIHMGPAVQ------APQMYPYPVSNSVPGQQGKYRG 746
+ G GL PQ+ P A P P ++ VPG
Sbjct: 509 QRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLS----- 563
Query: 747 AKGSLPPQRSDQ--------HQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQF--- 795
GS P RS + + S P + AGPP A+P + P P++
Sbjct: 564 PGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPP---ASPGKAQPP-KPERVTSL 619
Query: 796 --PGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTS-------GSHPQAIVS-SSTPQYPSA 845
PG + S AP +S P++LT HP+ S P P +
Sbjct: 620 RSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRS 679
Query: 846 EQPTPQALYATV------------HQSYPHHATQLHAHQPQPATT----PTGSQPQSQHA 889
P AL A QS P T L Q P + P S P S H
Sbjct: 680 PNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHP 739
Query: 890 APSPVQHQ--AGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQS-PQSSFPQPAAVY 946
P P + +AP S ++ L P PP PP P Q + FP P +
Sbjct: 740 PPPPTKKPEVVVEAPS-ASETAEEPLQDPN----WPPPPPPAPEEQDLSMADFPPPEEAF 794
Query: 947 AIHHQQLPHGFTNMAHVTQ--AHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGA 1004
P G + + A + TA PG+P PP P S
Sbjct: 795 FSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAK 854
Query: 1005 VPQSGVPALSASTPSPYPYIGHPQV 1029
+PQ S P +G P V
Sbjct: 855 LPQKEPVGCSKGGGPPREDVGAPLV 879
Score = 38.9 bits (89), Expect = 0.026
Identities = 32/116 (27%), Positives = 46/116 (39%), Gaps = 10/116 (8%)
Query: 5 QPLQQPSQPQQPPPTQQ----AVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
+PLQ P+ P PPP + ++A PP + + P P S + P +SP
Sbjct: 762 EPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGS---PELVSSPAAS 818
Query: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSAR---GQSTGKGPPQSPV 113
+A ++ P PP P PG A + G S G GPP+ V
Sbjct: 819 SSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDV 874
Score = 35.0 bits (79), Expect = 0.37
Identities = 31/117 (26%), Positives = 43/117 (36%), Gaps = 10/117 (8%)
Query: 3 KPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPG--PLATSAAPPGPPAAASPCLG 60
KP+ QQP P+ P A P +P N +PG P + P P SP G
Sbjct: 524 KPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSG 583
Query: 61 PVAAAGS------GLRRGAEGILAPQPPPPQQ--HQERPGAAAIGSARGQSTGKGPP 109
+ +G+ GL QPP P++ PGA+ S + P
Sbjct: 584 YSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDP 640
Score = 32.7 bits (73), Expect = 1.8
Identities = 31/114 (27%), Positives = 42/114 (36%), Gaps = 17/114 (14%)
Query: 10 PSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAA----PPGPPAAASPCL-GPVAA 64
PS+P+ P P A+A +PGP++T+ A PP P +P PV +
Sbjct: 674 PSKPRSPNPAAPALAAPAV---------VPGPVSTTDASPQSPPTPQTTLTPLQESPVIS 724
Query: 65 AGSGLRRGAEGILAPQPPP---PQQHQERPGAAAIGSARGQSTGKGPPQSPVFE 115
P PPP P+ E P A+ Q PP P E
Sbjct: 725 KDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPE 778
Score = 30.8 bits (68), Expect = 7.0
Identities = 23/80 (28%), Positives = 32/80 (40%), Gaps = 5/80 (6%)
Query: 33 PPNGGLPGPLATSAAPPGPPAAASPCL-GPVAAAGSGLRRGAEGILAPQPPPPQQHQERP 91
PP+ +P P + + P P A+P L P G A +PQ PP Q P
Sbjct: 661 PPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDA----SPQSPPTPQTTLTP 716
Query: 92 GAAAIGSARGQSTGKGPPQS 111
+ ++ QS PP S
Sbjct: 717 LQESPVISKDQSPPPSPPPS 736
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 70.9 bits (172), Expect = 6e-12
Identities = 128/566 (22%), Positives = 197/566 (34%), Gaps = 71/566 (12%)
Query: 394 PGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRP------SGETSVPPPPAVGRMYPP 447
P +A GP+ +PK P + S+ P S T+ P P
Sbjct: 197 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 256
Query: 448 RSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVK 507
+PK AP P P A T+ P T+ + +P +PK APT
Sbjct: 257 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK-KPAPT--- 312
Query: 508 ELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPF 567
+ KEP T P+E K P ++ + A K P++ E +
Sbjct: 313 --TPKEPAPT-TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA---- 365
Query: 568 PPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPP 627
P KE KE EP +P ++K+ + KE AP+ P P P
Sbjct: 366 -PTTPKEPAPTTTKEPSPTTPKEP--APTTTKSAPTTTKEP----APTTTKSAPTTPKEP 418
Query: 628 CPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNK--STSTPTSP 685
P+ T P K+ P + T P +P + K + +TP P
Sbjct: 419 SPTTTKEP----APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 474
Query: 686 GPRT--HSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGK 743
P T + P+ P +P+ ++ P PA P+ ++ + P +
Sbjct: 475 APTTPKETAPTTPKKLTPT----TPEKLA--PTTPEKPAPTTPE----ELAPTTPEE--- 521
Query: 744 YRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQ 803
P + +PA P +AAA P A T P P+ +PA
Sbjct: 522 ---------PTPTTPEEPAPTTP--KAAAPNTPKEPAPTTPKEPAPTTPK----EPAPTT 566
Query: 804 PMAHYPSQPV-FAPMLQSNPRMLT-SGSHPQAIVSSST--PQYPSAEQPTPQALYATVHQ 859
P P+ P AP P T P+ + ++T P + ++P P T
Sbjct: 567 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA-P 625
Query: 860 SYPHHATQLHAHQPQPATTPTGSQPQS-QHAAPSPVQHQAGQ--APHLGSGQPQQNLYHP 916
+ P +P P TTP G+ P + + AP+ + A + AP G P
Sbjct: 626 TTPKEPAPTTPKEPAP-TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 684
Query: 917 GALT--GTPPSLPPGPSAQSPQSSFP 940
T T P+ P P+ +P+ P
Sbjct: 685 APTTPKETAPTTPKEPAPTTPKKPAP 710
Score = 70.1 bits (170), Expect = 1e-11
Identities = 137/642 (21%), Positives = 202/642 (31%), Gaps = 84/642 (13%)
Query: 419 AKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASI 478
+K L+ P+ P ET+ P + P+ P P +++ P+ P PT+ S
Sbjct: 191 SKVLAKPT--PKAETTTKGPA----LTTPKEPTPTTPKEPASTTPKEP----TPTTIKSA 240
Query: 479 PVTSSVSDPGVGSISPASPKISLAPTDVKE---LSTKEPGRTLEPQELARIAGKVPGLQN 535
P T PA APT KE +TKEP T P+E A K P
Sbjct: 241 PTTPK---------EPAPTTTKSAPTTPKEPAPTTTKEPAPT-TPKEPAPTTTKEPA--- 287
Query: 536 EQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSP 595
S+P +P P K P KE EP +P
Sbjct: 288 -----------------PTTTKSAPTTPKEPAPTTPKKPAPT-TPKEPAPTTPKEP--TP 327
Query: 596 VSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG-SPPVGLIKGEDKDEGPVAEQV 654
+ K + + KE P P++P P P + + P K+ P +
Sbjct: 328 TTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE 387
Query: 655 KKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYI 714
T +A + + +TP P P T P+ T + +P+
Sbjct: 388 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA--PTTPKEPAPTTPK--KPA 443
Query: 715 PQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAA 774
P PA P+ P P + P A + P + + P + A
Sbjct: 444 PTTPKEPAPTTPK-EPAPTTTKKPAPTTPKEPAP-TTPKETAPTTPKKLTPTTPEKLAPT 501
Query: 775 GPPLVAATPYSSYIPYNPQQ----FPGQPAMMQPMAHYPSQPVF-APMLQSNPRMLTSGS 829
P A T P P++ P +PA P A P+ P AP P T
Sbjct: 502 TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 561
Query: 830 HPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHA 889
+ P P PT T+ + P + + P TT +
Sbjct: 562 PAPTTPKETAPTTPKGTAPT------TLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP 615
Query: 890 APSPVQHQAGQAPHLGSGQPQQNLYHPGALT--GTPPSLPPGPSAQSPQSSFPQPAAVYA 947
AP+ + G AP P T GT P+ P+ +P+ P+ A
Sbjct: 616 APTTPK---GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 672
Query: 948 IHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPH----------PPQVMLLHPPQSH 997
+ P T+ +T T P P P PP + P +
Sbjct: 673 ---TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTT 729
Query: 998 GGPPQ-GAVPQSGVPALSASTPSPYPYIGHPQVQSHPSQQLP 1038
P P P LSA P+P P+ P+ + P
Sbjct: 730 KEPTTIHKSPDESTPELSAE-PTPKALENSPKEPGVPTTKTP 770
Score = 62.8 bits (151), Expect = 2e-09
Identities = 107/502 (21%), Positives = 162/502 (32%), Gaps = 67/502 (13%)
Query: 406 SRMSPKAQRPLRGAKTLSSPSN--RPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCP 463
++ +P + T S+P+ PS T+ P P + P +PK AP P
Sbjct: 393 TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 452
Query: 464 EPPIGSAVPTSSASIPVTSSVSDPGV-GSISPASPKISLAPTDVKEL--STKEPGRTLEP 520
P A T+ P T P +P +PK L PT ++L +T E P
Sbjct: 453 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK-KLTPTTPEKLAPTTPEKPAPTTP 511
Query: 521 QELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFP-------PRILK 573
+ELA + P ++ +++P +P P P K
Sbjct: 512 EELAPTTPEEPTPTTPEEPAP-----------TTPKAAAPNTPKEPAPTTPKEPAPTTPK 560
Query: 574 EEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG 633
E KE + P G+ ++ E KP T E C
Sbjct: 561 EPAPTTPKET---APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 617
Query: 634 SPPVGLIKGEDKDEGPV-----AEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPR 688
+ P G K+ P A K T KE PT P K + T+ GP
Sbjct: 618 TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP- 676
Query: 689 THSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAK 748
T +T P T + P PA P+ P P + P
Sbjct: 677 TSTTSDKPAPTTPK---------ETAPTTPKEPAPTTPKK-PAPTTPETP---------- 716
Query: 749 GSLPPQRSDQHQPASA--PPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMA 806
PP S+ P + P + + P ++A P + +P++ PG P P A
Sbjct: 717 ---PPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKE-PGVPTTKTPAA 772
Query: 807 HYPSQPVFAP------MLQSNPRMLTSGSHPQAIVSSSTPQYPSAE--QPTPQALYATVH 858
P A L++ P T+ +++T + ++ T Q T
Sbjct: 773 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQ 832
Query: 859 QSYPHHATQLHAHQPQPATTPT 880
+ P T L P T T
Sbjct: 833 DTTPFKITTLKTTTLAPKVTTT 854
Score = 61.2 bits (147), Expect = 5e-09
Identities = 113/544 (20%), Positives = 176/544 (32%), Gaps = 67/544 (12%)
Query: 381 PRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPA 440
P+ P P P + P +P + P +P+ + P PA
Sbjct: 306 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 365
Query: 441 VGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKIS 500
P + P+P + P PT++ S P T+ P +P +PK
Sbjct: 366 PTTPKEPAPTTTKEPSPTTPKEP-------APTTTKSAPTTTKEPAPTTTKSAPTTPK-E 417
Query: 501 LAPTDVKE---LSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPS 557
+PT KE + KEP T P++ A K P ++ + K
Sbjct: 418 PSPTTTKEPAPTTPKEPAPT-TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP 476
Query: 558 SSPENSLDPFPPRILKEEPK---GKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAP 614
++P+ + P ++ P+ E T E + + + +E P
Sbjct: 477 TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPK 536
Query: 615 SGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGP--VAEQVKKSTLNPNAKEFNPTKPL 672
+ P++P P P + P E P A K T KE PT P
Sbjct: 537 AAAPNTPKEPAPTTPKE----PAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK 592
Query: 673 LSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYP 732
K + T+ P T +T P P G A P+ P P
Sbjct: 593 KPAPKELAPTTTKEP-TSTTCDKPA-----------------PTTPKGTAPTTPK-EPAP 633
Query: 733 VSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLV---AATPYSSYIP 789
+ P KG+ P + +PA P A P +T P
Sbjct: 634 TTPKEPAP----TTPKGTAP---TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAP 686
Query: 790 YNPQQ----FPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSS---STPQY 842
P++ P +PA P P+ P P S T+ P I S STP+
Sbjct: 687 TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 746
Query: 843 PSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTG--------SQPQSQHAAPSPV 894
+ +PTP+AL + + A +P+ TT + P++ AAP
Sbjct: 747 --SAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT 804
Query: 895 QHQA 898
+ A
Sbjct: 805 KETA 808
Score = 45.1 bits (105), Expect = 4e-04
Identities = 73/315 (23%), Positives = 110/315 (34%), Gaps = 59/315 (18%)
Query: 405 PSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPE 464
P+ +PK P A T + P+ TS P P + P +PK AP P
Sbjct: 655 PAPTTPKKPAPKELAPTTTKG---PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT 711
Query: 465 PPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPT-DVKELSTKEPGRTLEPQEL 523
P TS S P T+ S ++P++S PT E S KEPG P
Sbjct: 712 TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPG---VPTTK 768
Query: 524 ARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEV 583
A K + + +LR ++PE + P++ KE EK
Sbjct: 769 TPAATKPEMTTTAKDKTTERDLR-----------TTPETT--TAAPKMTKETATTTEKTT 815
Query: 584 DGLLTSEPMGSPVSSKTESVSDKEDKP---------PLAPSGGT-----------EGPEQ 623
+ +T+ +++ S + ++ P LAP T PE+
Sbjct: 816 ESKITA------TTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEE 869
Query: 624 PPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTP- 682
P T S K P ++ K+ P + + T P + K+T TP
Sbjct: 870 TAKPKDRATNS----------KATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPR 919
Query: 683 --TSPGPRTHSTPSI 695
TS P + T I
Sbjct: 920 KMTSTMPELNPTSRI 934
Score = 42.4 bits (98), Expect = 0.002
Identities = 97/476 (20%), Positives = 141/476 (29%), Gaps = 48/476 (10%)
Query: 589 SEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEG 648
S P S S +T +KE + T + + + K KD
Sbjct: 129 SLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLA 188
Query: 649 PVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSP 708
P ++ + K T P A E P L+ K TPT+P +TP P T +S +P
Sbjct: 189 PTSKVLAKPT--PKA-ETTTKGPALTTPKEP-TPTTPKEPASTTPKEPTPTTIKSAPTTP 244
Query: 709 QYIS-------------YIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQR 755
+ + P PA P+ P P + P P
Sbjct: 245 KEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPK-EPAPTTTKEPAPTTTKSAPTTPKEPAP 303
Query: 756 SDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFA 815
+ +PA P A P TP + P + P +P P +P A
Sbjct: 304 TTPKKPAPTTPKEPAPTTPKEP----TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKP--A 357
Query: 816 PMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHA----H 871
P P T +P P PT T + P T A
Sbjct: 358 PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE-PAPTTTKSAPTTPK 416
Query: 872 QPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGT---PPSLPP 928
+P P TT + + AP+ + A P +P A T T P+ P
Sbjct: 417 EPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPK----EPAPTTPKEPAPTTTKKPAPTTPK 472
Query: 929 GPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQV 988
P+ +P+ + P P T A A P AP P+
Sbjct: 473 EPAPTTPKETAP-----------TTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE 521
Query: 989 MLLHPPQSHG-GPPQGAVPQSGVPALSASTPSPYPYIGHPQVQSHPSQQLPFHPPG 1043
P+ P+ A P + + P P + P + P P G
Sbjct: 522 PTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG 577
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 70.9 bits (172), Expect = 6e-12
Identities = 128/566 (22%), Positives = 197/566 (34%), Gaps = 71/566 (12%)
Query: 394 PGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRP------SGETSVPPPPAVGRMYPP 447
P +A GP+ +PK P + S+ P S T+ P P
Sbjct: 238 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 297
Query: 448 RSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVK 507
+PK AP P P A T+ P T+ + +P +PK APT
Sbjct: 298 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK-KPAPT--- 353
Query: 508 ELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPF 567
+ KEP T P+E K P ++ + A K P++ E +
Sbjct: 354 --TPKEPAPT-TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA---- 406
Query: 568 PPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPP 627
P KE KE EP +P ++K+ + KE AP+ P P P
Sbjct: 407 -PTTPKEPAPTTTKEPSPTTPKEP--APTTTKSAPTTTKEP----APTTTKSAPTTPKEP 459
Query: 628 CPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNK--STSTPTSP 685
P+ T P K+ P + T P +P + K + +TP P
Sbjct: 460 SPTTTKEP----APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 515
Query: 686 GPRT--HSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGK 743
P T + P+ P +P+ ++ P PA P+ ++ + P +
Sbjct: 516 APTTPKETAPTTPKKLTPT----TPEKLA--PTTPEKPAPTTPE----ELAPTTPEE--- 562
Query: 744 YRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQ 803
P + +PA P +AAA P A T P P+ +PA
Sbjct: 563 ---------PTPTTPEEPAPTTP--KAAAPNTPKEPAPTTPKEPAPTTPK----EPAPTT 607
Query: 804 PMAHYPSQPV-FAPMLQSNPRMLT-SGSHPQAIVSSST--PQYPSAEQPTPQALYATVHQ 859
P P+ P AP P T P+ + ++T P + ++P P T
Sbjct: 608 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA-P 666
Query: 860 SYPHHATQLHAHQPQPATTPTGSQPQS-QHAAPSPVQHQAGQ--APHLGSGQPQQNLYHP 916
+ P +P P TTP G+ P + + AP+ + A + AP G P
Sbjct: 667 TTPKEPAPTTPKEPAP-TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 725
Query: 917 GALT--GTPPSLPPGPSAQSPQSSFP 940
T T P+ P P+ +P+ P
Sbjct: 726 APTTPKETAPTTPKEPAPTTPKKPAP 751
Score = 70.1 bits (170), Expect = 1e-11
Identities = 137/642 (21%), Positives = 202/642 (31%), Gaps = 84/642 (13%)
Query: 419 AKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASI 478
+K L+ P+ P ET+ P + P+ P P +++ P+ P PT+ S
Sbjct: 232 SKVLAKPT--PKAETTTKGPA----LTTPKEPTPTTPKEPASTTPKEP----TPTTIKSA 281
Query: 479 PVTSSVSDPGVGSISPASPKISLAPTDVKE---LSTKEPGRTLEPQELARIAGKVPGLQN 535
P T PA APT KE +TKEP T P+E A K P
Sbjct: 282 PTTPK---------EPAPTTTKSAPTTPKEPAPTTTKEPAPT-TPKEPAPTTTKEPA--- 328
Query: 536 EQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSP 595
S+P +P P K P KE EP +P
Sbjct: 329 -----------------PTTTKSAPTTPKEPAPTTPKKPAPT-TPKEPAPTTPKEP--TP 368
Query: 596 VSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG-SPPVGLIKGEDKDEGPVAEQV 654
+ K + + KE P P++P P P + + P K+ P +
Sbjct: 369 TTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE 428
Query: 655 KKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYI 714
T +A + + +TP P P T P+ T + +P+
Sbjct: 429 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA--PTTPKEPAPTTPK--KPA 484
Query: 715 PQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAA 774
P PA P+ P P + P A + P + + P + A
Sbjct: 485 PTTPKEPAPTTPK-EPAPTTTKKPAPTTPKEPAP-TTPKETAPTTPKKLTPTTPEKLAPT 542
Query: 775 GPPLVAATPYSSYIPYNPQQ----FPGQPAMMQPMAHYPSQPVF-APMLQSNPRMLTSGS 829
P A T P P++ P +PA P A P+ P AP P T
Sbjct: 543 TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 602
Query: 830 HPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHA 889
+ P P PT T+ + P + + P TT +
Sbjct: 603 PAPTTPKETAPTTPKGTAPT------TLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP 656
Query: 890 APSPVQHQAGQAPHLGSGQPQQNLYHPGALT--GTPPSLPPGPSAQSPQSSFPQPAAVYA 947
AP+ + G AP P T GT P+ P+ +P+ P+ A
Sbjct: 657 APTTPK---GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 713
Query: 948 IHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPH----------PPQVMLLHPPQSH 997
+ P T+ +T T P P P PP + P +
Sbjct: 714 ---TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTT 770
Query: 998 GGPPQ-GAVPQSGVPALSASTPSPYPYIGHPQVQSHPSQQLP 1038
P P P LSA P+P P+ P+ + P
Sbjct: 771 KEPTTIHKSPDESTPELSAE-PTPKALENSPKEPGVPTTKTP 811
Score = 62.8 bits (151), Expect = 2e-09
Identities = 107/502 (21%), Positives = 162/502 (32%), Gaps = 67/502 (13%)
Query: 406 SRMSPKAQRPLRGAKTLSSPSN--RPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCP 463
++ +P + T S+P+ PS T+ P P + P +PK AP P
Sbjct: 434 TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 493
Query: 464 EPPIGSAVPTSSASIPVTSSVSDPGV-GSISPASPKISLAPTDVKEL--STKEPGRTLEP 520
P A T+ P T P +P +PK L PT ++L +T E P
Sbjct: 494 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK-KLTPTTPEKLAPTTPEKPAPTTP 552
Query: 521 QELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFP-------PRILK 573
+ELA + P ++ +++P +P P P K
Sbjct: 553 EELAPTTPEEPTPTTPEEPAP-----------TTPKAAAPNTPKEPAPTTPKEPAPTTPK 601
Query: 574 EEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG 633
E KE + P G+ ++ E KP T E C
Sbjct: 602 EPAPTTPKET---APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 658
Query: 634 SPPVGLIKGEDKDEGPV-----AEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPR 688
+ P G K+ P A K T KE PT P K + T+ GP
Sbjct: 659 TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP- 717
Query: 689 THSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAK 748
T +T P T + P PA P+ P P + P
Sbjct: 718 TSTTSDKPAPTTPK---------ETAPTTPKEPAPTTPKK-PAPTTPETP---------- 757
Query: 749 GSLPPQRSDQHQPASA--PPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMA 806
PP S+ P + P + + P ++A P + +P++ PG P P A
Sbjct: 758 ---PPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKE-PGVPTTKTPAA 813
Query: 807 HYPSQPVFAP------MLQSNPRMLTSGSHPQAIVSSSTPQYPSAE--QPTPQALYATVH 858
P A L++ P T+ +++T + ++ T Q T
Sbjct: 814 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQ 873
Query: 859 QSYPHHATQLHAHQPQPATTPT 880
+ P T L P T T
Sbjct: 874 DTTPFKITTLKTTTLAPKVTTT 895
Score = 61.2 bits (147), Expect = 5e-09
Identities = 113/544 (20%), Positives = 176/544 (32%), Gaps = 67/544 (12%)
Query: 381 PRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPA 440
P+ P P P + P +P + P +P+ + P PA
Sbjct: 347 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 406
Query: 441 VGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKIS 500
P + P+P + P PT++ S P T+ P +P +PK
Sbjct: 407 PTTPKEPAPTTTKEPSPTTPKEP-------APTTTKSAPTTTKEPAPTTTKSAPTTPK-E 458
Query: 501 LAPTDVKE---LSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPS 557
+PT KE + KEP T P++ A K P ++ + K
Sbjct: 459 PSPTTTKEPAPTTPKEPAPT-TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP 517
Query: 558 SSPENSLDPFPPRILKEEPK---GKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAP 614
++P+ + P ++ P+ E T E + + + +E P
Sbjct: 518 TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPK 577
Query: 615 SGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGP--VAEQVKKSTLNPNAKEFNPTKPL 672
+ P++P P P + P E P A K T KE PT P
Sbjct: 578 AAAPNTPKEPAPTTPKE----PAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK 633
Query: 673 LSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYP 732
K + T+ P T +T P P G A P+ P P
Sbjct: 634 KPAPKELAPTTTKEP-TSTTCDKPA-----------------PTTPKGTAPTTPK-EPAP 674
Query: 733 VSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLV---AATPYSSYIP 789
+ P KG+ P + +PA P A P +T P
Sbjct: 675 TTPKEPAP----TTPKGTAP---TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAP 727
Query: 790 YNPQQ----FPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSS---STPQY 842
P++ P +PA P P+ P P S T+ P I S STP+
Sbjct: 728 TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 787
Query: 843 PSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTG--------SQPQSQHAAPSPV 894
+ +PTP+AL + + A +P+ TT + P++ AAP
Sbjct: 788 --SAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT 845
Query: 895 QHQA 898
+ A
Sbjct: 846 KETA 849
Score = 45.1 bits (105), Expect = 4e-04
Identities = 73/315 (23%), Positives = 110/315 (34%), Gaps = 59/315 (18%)
Query: 405 PSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPE 464
P+ +PK P A T + P+ TS P P + P +PK AP P
Sbjct: 696 PAPTTPKKPAPKELAPTTTKG---PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT 752
Query: 465 PPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPT-DVKELSTKEPGRTLEPQEL 523
P TS S P T+ S ++P++S PT E S KEPG P
Sbjct: 753 TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPG---VPTTK 809
Query: 524 ARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEV 583
A K + + +LR ++PE + P++ KE EK
Sbjct: 810 TPAATKPEMTTTAKDKTTERDLR-----------TTPETT--TAAPKMTKETATTTEKTT 856
Query: 584 DGLLTSEPMGSPVSSKTESVSDKEDKP---------PLAPSGGT-----------EGPEQ 623
+ +T+ +++ S + ++ P LAP T PE+
Sbjct: 857 ESKITA------TTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEE 910
Query: 624 PPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTP- 682
P T S K P ++ K+ P + + T P + K+T TP
Sbjct: 911 TAKPKDRATNS----------KATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPR 960
Query: 683 --TSPGPRTHSTPSI 695
TS P + T I
Sbjct: 961 KMTSTMPELNPTSRI 975
Score = 42.4 bits (98), Expect = 0.002
Identities = 97/476 (20%), Positives = 141/476 (29%), Gaps = 48/476 (10%)
Query: 589 SEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEG 648
S P S S +T +KE + T + + + K KD
Sbjct: 170 SLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLA 229
Query: 649 PVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSP 708
P ++ + K T P A E P L+ K TPT+P +TP P T +S +P
Sbjct: 230 PTSKVLAKPT--PKA-ETTTKGPALTTPKEP-TPTTPKEPASTTPKEPTPTTIKSAPTTP 285
Query: 709 QYIS-------------YIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQR 755
+ + P PA P+ P P + P P
Sbjct: 286 KEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPK-EPAPTTTKEPAPTTTKSAPTTPKEPAP 344
Query: 756 SDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFA 815
+ +PA P A P TP + P + P +P P +P A
Sbjct: 345 TTPKKPAPTTPKEPAPTTPKEP----TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKP--A 398
Query: 816 PMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHA----H 871
P P T +P P PT T + P T A
Sbjct: 399 PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE-PAPTTTKSAPTTPK 457
Query: 872 QPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGT---PPSLPP 928
+P P TT + + AP+ + A P +P A T T P+ P
Sbjct: 458 EPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPK----EPAPTTPKEPAPTTTKKPAPTTPK 513
Query: 929 GPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQV 988
P+ +P+ + P P T A A P AP P+
Sbjct: 514 EPAPTTPKETAP-----------TTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE 562
Query: 989 MLLHPPQSHG-GPPQGAVPQSGVPALSASTPSPYPYIGHPQVQSHPSQQLPFHPPG 1043
P+ P+ A P + + P P + P + P P G
Sbjct: 563 PTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG 618
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 70.9 bits (172), Expect = 6e-12
Identities = 128/566 (22%), Positives = 197/566 (34%), Gaps = 71/566 (12%)
Query: 394 PGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRP------SGETSVPPPPAVGRMYPP 447
P +A GP+ +PK P + S+ P S T+ P P
Sbjct: 290 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 349
Query: 448 RSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVK 507
+PK AP P P A T+ P T+ + +P +PK APT
Sbjct: 350 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK-KPAPT--- 405
Query: 508 ELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPF 567
+ KEP T P+E K P ++ + A K P++ E +
Sbjct: 406 --TPKEPAPT-TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA---- 458
Query: 568 PPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPP 627
P KE KE EP +P ++K+ + KE AP+ P P P
Sbjct: 459 -PTTPKEPAPTTTKEPSPTTPKEP--APTTTKSAPTTTKEP----APTTTKSAPTTPKEP 511
Query: 628 CPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNK--STSTPTSP 685
P+ T P K+ P + T P +P + K + +TP P
Sbjct: 512 SPTTTKEP----APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 567
Query: 686 GPRT--HSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGK 743
P T + P+ P +P+ ++ P PA P+ ++ + P +
Sbjct: 568 APTTPKETAPTTPKKLTPT----TPEKLA--PTTPEKPAPTTPE----ELAPTTPEE--- 614
Query: 744 YRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQ 803
P + +PA P +AAA P A T P P+ +PA
Sbjct: 615 ---------PTPTTPEEPAPTTP--KAAAPNTPKEPAPTTPKEPAPTTPK----EPAPTT 659
Query: 804 PMAHYPSQPV-FAPMLQSNPRMLT-SGSHPQAIVSSST--PQYPSAEQPTPQALYATVHQ 859
P P+ P AP P T P+ + ++T P + ++P P T
Sbjct: 660 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA-P 718
Query: 860 SYPHHATQLHAHQPQPATTPTGSQPQS-QHAAPSPVQHQAGQ--APHLGSGQPQQNLYHP 916
+ P +P P TTP G+ P + + AP+ + A + AP G P
Sbjct: 719 TTPKEPAPTTPKEPAP-TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 777
Query: 917 GALT--GTPPSLPPGPSAQSPQSSFP 940
T T P+ P P+ +P+ P
Sbjct: 778 APTTPKETAPTTPKEPAPTTPKKPAP 803
Score = 70.1 bits (170), Expect = 1e-11
Identities = 137/642 (21%), Positives = 202/642 (31%), Gaps = 84/642 (13%)
Query: 419 AKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASI 478
+K L+ P+ P ET+ P + P+ P P +++ P+ P PT+ S
Sbjct: 284 SKVLAKPT--PKAETTTKGPA----LTTPKEPTPTTPKEPASTTPKEP----TPTTIKSA 333
Query: 479 PVTSSVSDPGVGSISPASPKISLAPTDVKE---LSTKEPGRTLEPQELARIAGKVPGLQN 535
P T PA APT KE +TKEP T P+E A K P
Sbjct: 334 PTTPK---------EPAPTTTKSAPTTPKEPAPTTTKEPAPT-TPKEPAPTTTKEPA--- 380
Query: 536 EQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSP 595
S+P +P P K P KE EP +P
Sbjct: 381 -----------------PTTTKSAPTTPKEPAPTTPKKPAPT-TPKEPAPTTPKEP--TP 420
Query: 596 VSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG-SPPVGLIKGEDKDEGPVAEQV 654
+ K + + KE P P++P P P + + P K+ P +
Sbjct: 421 TTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE 480
Query: 655 KKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYI 714
T +A + + +TP P P T P+ T + +P+
Sbjct: 481 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA--PTTPKEPAPTTPK--KPA 536
Query: 715 PQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAA 774
P PA P+ P P + P A + P + + P + A
Sbjct: 537 PTTPKEPAPTTPK-EPAPTTTKKPAPTTPKEPAP-TTPKETAPTTPKKLTPTTPEKLAPT 594
Query: 775 GPPLVAATPYSSYIPYNPQQ----FPGQPAMMQPMAHYPSQPVF-APMLQSNPRMLTSGS 829
P A T P P++ P +PA P A P+ P AP P T
Sbjct: 595 TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 654
Query: 830 HPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHA 889
+ P P PT T+ + P + + P TT +
Sbjct: 655 PAPTTPKETAPTTPKGTAPT------TLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP 708
Query: 890 APSPVQHQAGQAPHLGSGQPQQNLYHPGALT--GTPPSLPPGPSAQSPQSSFPQPAAVYA 947
AP+ + G AP P T GT P+ P+ +P+ P+ A
Sbjct: 709 APTTPK---GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 765
Query: 948 IHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPH----------PPQVMLLHPPQSH 997
+ P T+ +T T P P P PP + P +
Sbjct: 766 ---TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTT 822
Query: 998 GGPPQ-GAVPQSGVPALSASTPSPYPYIGHPQVQSHPSQQLP 1038
P P P LSA P+P P+ P+ + P
Sbjct: 823 KEPTTIHKSPDESTPELSAE-PTPKALENSPKEPGVPTTKTP 863
Score = 62.8 bits (151), Expect = 2e-09
Identities = 107/502 (21%), Positives = 162/502 (32%), Gaps = 67/502 (13%)
Query: 406 SRMSPKAQRPLRGAKTLSSPSN--RPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCP 463
++ +P + T S+P+ PS T+ P P + P +PK AP P
Sbjct: 486 TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 545
Query: 464 EPPIGSAVPTSSASIPVTSSVSDPGV-GSISPASPKISLAPTDVKEL--STKEPGRTLEP 520
P A T+ P T P +P +PK L PT ++L +T E P
Sbjct: 546 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK-KLTPTTPEKLAPTTPEKPAPTTP 604
Query: 521 QELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFP-------PRILK 573
+ELA + P ++ +++P +P P P K
Sbjct: 605 EELAPTTPEEPTPTTPEEPAP-----------TTPKAAAPNTPKEPAPTTPKEPAPTTPK 653
Query: 574 EEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG 633
E KE + P G+ ++ E KP T E C
Sbjct: 654 EPAPTTPKET---APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 710
Query: 634 SPPVGLIKGEDKDEGPV-----AEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPR 688
+ P G K+ P A K T KE PT P K + T+ GP
Sbjct: 711 TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP- 769
Query: 689 THSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAK 748
T +T P T + P PA P+ P P + P
Sbjct: 770 TSTTSDKPAPTTPK---------ETAPTTPKEPAPTTPKK-PAPTTPETP---------- 809
Query: 749 GSLPPQRSDQHQPASA--PPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMA 806
PP S+ P + P + + P ++A P + +P++ PG P P A
Sbjct: 810 ---PPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKE-PGVPTTKTPAA 865
Query: 807 HYPSQPVFAP------MLQSNPRMLTSGSHPQAIVSSSTPQYPSAE--QPTPQALYATVH 858
P A L++ P T+ +++T + ++ T Q T
Sbjct: 866 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQ 925
Query: 859 QSYPHHATQLHAHQPQPATTPT 880
+ P T L P T T
Sbjct: 926 DTTPFKITTLKTTTLAPKVTTT 947
Score = 61.2 bits (147), Expect = 5e-09
Identities = 113/544 (20%), Positives = 176/544 (32%), Gaps = 67/544 (12%)
Query: 381 PRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPA 440
P+ P P P + P +P + P +P+ + P PA
Sbjct: 399 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 458
Query: 441 VGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKIS 500
P + P+P + P PT++ S P T+ P +P +PK
Sbjct: 459 PTTPKEPAPTTTKEPSPTTPKEP-------APTTTKSAPTTTKEPAPTTTKSAPTTPK-E 510
Query: 501 LAPTDVKE---LSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPS 557
+PT KE + KEP T P++ A K P ++ + K
Sbjct: 511 PSPTTTKEPAPTTPKEPAPT-TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP 569
Query: 558 SSPENSLDPFPPRILKEEPK---GKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAP 614
++P+ + P ++ P+ E T E + + + +E P
Sbjct: 570 TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPK 629
Query: 615 SGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGP--VAEQVKKSTLNPNAKEFNPTKPL 672
+ P++P P P + P E P A K T KE PT P
Sbjct: 630 AAAPNTPKEPAPTTPKE----PAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK 685
Query: 673 LSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYP 732
K + T+ P T +T P P G A P+ P P
Sbjct: 686 KPAPKELAPTTTKEP-TSTTCDKPA-----------------PTTPKGTAPTTPK-EPAP 726
Query: 733 VSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLV---AATPYSSYIP 789
+ P KG+ P + +PA P A P +T P
Sbjct: 727 TTPKEPAP----TTPKGTAP---TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAP 779
Query: 790 YNPQQ----FPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSS---STPQY 842
P++ P +PA P P+ P P S T+ P I S STP+
Sbjct: 780 TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 839
Query: 843 PSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTG--------SQPQSQHAAPSPV 894
+ +PTP+AL + + A +P+ TT + P++ AAP
Sbjct: 840 --SAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT 897
Query: 895 QHQA 898
+ A
Sbjct: 898 KETA 901
Score = 45.4 bits (106), Expect = 3e-04
Identities = 127/640 (19%), Positives = 199/640 (31%), Gaps = 62/640 (9%)
Query: 432 ETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGS 491
E P P + PP S S + P+PP S +T S
Sbjct: 65 EVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQE 124
Query: 492 ISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGA- 550
S +S S + T K S+K E Q+ ++ ++ + + + G+
Sbjct: 125 SSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSG 184
Query: 551 ----QFKLQP--SSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVS 604
FK+ +S+ +++ P+I +P + + S +K +V
Sbjct: 185 LDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVE 244
Query: 605 DKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAK 664
KE + T+G E+ +Q+ + K KD P ++ + K T P A
Sbjct: 245 TKETTTTNKQTS-TDGKEKTTSAKETQS------IEKTSAKDLAPTSKVLAKPT--PKA- 294
Query: 665 EFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYIS------------ 712
E P L+ K TPT+P +TP P T +S +P+ +
Sbjct: 295 ETTTKGPALTTPKEP-TPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPK 353
Query: 713 -YIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAA 771
P PA P+ P P + P P + +PA P A
Sbjct: 354 EPAPTTTKEPAPTTPK-EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP 412
Query: 772 AAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHP 831
P TP + P + P +P P +P AP P T
Sbjct: 413 TTPKEP----TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKP--APTTPKEPAPTTPKEPA 466
Query: 832 QAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHA----HQPQPATTPTGSQPQSQ 887
+P P PT T + P T A +P P TT + +
Sbjct: 467 PTTTKEPSPTTPKEPAPTTTKSAPTTTKE-PAPTTTKSAPTTPKEPSPTTTKEPAPTTPK 525
Query: 888 HAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGT---PPSLPPGPSAQSPQSSFPQPAA 944
AP+ + A P +P A T T P+ P P+ +P+ + P
Sbjct: 526 EPAPTTPKKPAPTTPK----EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAP---- 577
Query: 945 VYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHG-GPPQG 1003
P T A A P AP P+ P+ P+
Sbjct: 578 -------TTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKA 630
Query: 1004 AVPQSGVPALSASTPSPYPYIGHPQVQSHPSQQLPFHPPG 1043
A P + + P P + P + P P G
Sbjct: 631 AAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG 670
Score = 45.1 bits (105), Expect = 4e-04
Identities = 73/315 (23%), Positives = 110/315 (34%), Gaps = 59/315 (18%)
Query: 405 PSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPE 464
P+ +PK P A T + P+ TS P P + P +PK AP P
Sbjct: 748 PAPTTPKKPAPKELAPTTTKG---PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT 804
Query: 465 PPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPT-DVKELSTKEPGRTLEPQEL 523
P TS S P T+ S ++P++S PT E S KEPG P
Sbjct: 805 TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPG---VPTTK 861
Query: 524 ARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEV 583
A K + + +LR ++PE + P++ KE EK
Sbjct: 862 TPAATKPEMTTTAKDKTTERDLR-----------TTPETT--TAAPKMTKETATTTEKTT 908
Query: 584 DGLLTSEPMGSPVSSKTESVSDKEDKP---------PLAPSGGT-----------EGPEQ 623
+ +T+ +++ S + ++ P LAP T PE+
Sbjct: 909 ESKITA------TTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEE 962
Query: 624 PPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTP- 682
P T S K P ++ K+ P + + T P + K+T TP
Sbjct: 963 TAKPKDRATNS----------KATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPR 1012
Query: 683 --TSPGPRTHSTPSI 695
TS P + T I
Sbjct: 1013 KMTSTMPELNPTSRI 1027
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 70.9 bits (172), Expect = 6e-12
Identities = 128/566 (22%), Positives = 197/566 (34%), Gaps = 71/566 (12%)
Query: 394 PGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRP------SGETSVPPPPAVGRMYPP 447
P +A GP+ +PK P + S+ P S T+ P P
Sbjct: 331 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 390
Query: 448 RSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVK 507
+PK AP P P A T+ P T+ + +P +PK APT
Sbjct: 391 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK-KPAPT--- 446
Query: 508 ELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPF 567
+ KEP T P+E K P ++ + A K P++ E +
Sbjct: 447 --TPKEPAPT-TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA---- 499
Query: 568 PPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPP 627
P KE KE EP +P ++K+ + KE AP+ P P P
Sbjct: 500 -PTTPKEPAPTTTKEPSPTTPKEP--APTTTKSAPTTTKEP----APTTTKSAPTTPKEP 552
Query: 628 CPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNK--STSTPTSP 685
P+ T P K+ P + T P +P + K + +TP P
Sbjct: 553 SPTTTKEP----APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 608
Query: 686 GPRT--HSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGK 743
P T + P+ P +P+ ++ P PA P+ ++ + P +
Sbjct: 609 APTTPKETAPTTPKKLTPT----TPEKLA--PTTPEKPAPTTPE----ELAPTTPEE--- 655
Query: 744 YRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQ 803
P + +PA P +AAA P A T P P+ +PA
Sbjct: 656 ---------PTPTTPEEPAPTTP--KAAAPNTPKEPAPTTPKEPAPTTPK----EPAPTT 700
Query: 804 PMAHYPSQPV-FAPMLQSNPRMLT-SGSHPQAIVSSST--PQYPSAEQPTPQALYATVHQ 859
P P+ P AP P T P+ + ++T P + ++P P T
Sbjct: 701 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA-P 759
Query: 860 SYPHHATQLHAHQPQPATTPTGSQPQS-QHAAPSPVQHQAGQ--APHLGSGQPQQNLYHP 916
+ P +P P TTP G+ P + + AP+ + A + AP G P
Sbjct: 760 TTPKEPAPTTPKEPAP-TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 818
Query: 917 GALT--GTPPSLPPGPSAQSPQSSFP 940
T T P+ P P+ +P+ P
Sbjct: 819 APTTPKETAPTTPKEPAPTTPKKPAP 844
Score = 70.1 bits (170), Expect = 1e-11
Identities = 137/642 (21%), Positives = 202/642 (31%), Gaps = 84/642 (13%)
Query: 419 AKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASI 478
+K L+ P+ P ET+ P + P+ P P +++ P+ P PT+ S
Sbjct: 325 SKVLAKPT--PKAETTTKGPA----LTTPKEPTPTTPKEPASTTPKEP----TPTTIKSA 374
Query: 479 PVTSSVSDPGVGSISPASPKISLAPTDVKE---LSTKEPGRTLEPQELARIAGKVPGLQN 535
P T PA APT KE +TKEP T P+E A K P
Sbjct: 375 PTTPK---------EPAPTTTKSAPTTPKEPAPTTTKEPAPT-TPKEPAPTTTKEPA--- 421
Query: 536 EQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSP 595
S+P +P P K P KE EP +P
Sbjct: 422 -----------------PTTTKSAPTTPKEPAPTTPKKPAPT-TPKEPAPTTPKEP--TP 461
Query: 596 VSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG-SPPVGLIKGEDKDEGPVAEQV 654
+ K + + KE P P++P P P + + P K+ P +
Sbjct: 462 TTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE 521
Query: 655 KKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYI 714
T +A + + +TP P P T P+ T + +P+
Sbjct: 522 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA--PTTPKEPAPTTPK--KPA 577
Query: 715 PQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAA 774
P PA P+ P P + P A + P + + P + A
Sbjct: 578 PTTPKEPAPTTPK-EPAPTTTKKPAPTTPKEPAP-TTPKETAPTTPKKLTPTTPEKLAPT 635
Query: 775 GPPLVAATPYSSYIPYNPQQ----FPGQPAMMQPMAHYPSQPVF-APMLQSNPRMLTSGS 829
P A T P P++ P +PA P A P+ P AP P T
Sbjct: 636 TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 695
Query: 830 HPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHA 889
+ P P PT T+ + P + + P TT +
Sbjct: 696 PAPTTPKETAPTTPKGTAPT------TLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP 749
Query: 890 APSPVQHQAGQAPHLGSGQPQQNLYHPGALT--GTPPSLPPGPSAQSPQSSFPQPAAVYA 947
AP+ + G AP P T GT P+ P+ +P+ P+ A
Sbjct: 750 APTTPK---GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 806
Query: 948 IHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPH----------PPQVMLLHPPQSH 997
+ P T+ +T T P P P PP + P +
Sbjct: 807 ---TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTT 863
Query: 998 GGPPQ-GAVPQSGVPALSASTPSPYPYIGHPQVQSHPSQQLP 1038
P P P LSA P+P P+ P+ + P
Sbjct: 864 KEPTTIHKSPDESTPELSAE-PTPKALENSPKEPGVPTTKTP 904
Score = 62.8 bits (151), Expect = 2e-09
Identities = 107/502 (21%), Positives = 162/502 (32%), Gaps = 67/502 (13%)
Query: 406 SRMSPKAQRPLRGAKTLSSPSN--RPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCP 463
++ +P + T S+P+ PS T+ P P + P +PK AP P
Sbjct: 527 TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 586
Query: 464 EPPIGSAVPTSSASIPVTSSVSDPGV-GSISPASPKISLAPTDVKEL--STKEPGRTLEP 520
P A T+ P T P +P +PK L PT ++L +T E P
Sbjct: 587 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK-KLTPTTPEKLAPTTPEKPAPTTP 645
Query: 521 QELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFP-------PRILK 573
+ELA + P ++ +++P +P P P K
Sbjct: 646 EELAPTTPEEPTPTTPEEPAP-----------TTPKAAAPNTPKEPAPTTPKEPAPTTPK 694
Query: 574 EEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG 633
E KE + P G+ ++ E KP T E C
Sbjct: 695 EPAPTTPKET---APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 751
Query: 634 SPPVGLIKGEDKDEGPV-----AEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPR 688
+ P G K+ P A K T KE PT P K + T+ GP
Sbjct: 752 TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP- 810
Query: 689 THSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAK 748
T +T P T + P PA P+ P P + P
Sbjct: 811 TSTTSDKPAPTTPK---------ETAPTTPKEPAPTTPKK-PAPTTPETP---------- 850
Query: 749 GSLPPQRSDQHQPASA--PPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMA 806
PP S+ P + P + + P ++A P + +P++ PG P P A
Sbjct: 851 ---PPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKE-PGVPTTKTPAA 906
Query: 807 HYPSQPVFAP------MLQSNPRMLTSGSHPQAIVSSSTPQYPSAE--QPTPQALYATVH 858
P A L++ P T+ +++T + ++ T Q T
Sbjct: 907 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQ 966
Query: 859 QSYPHHATQLHAHQPQPATTPT 880
+ P T L P T T
Sbjct: 967 DTTPFKITTLKTTTLAPKVTTT 988
Score = 61.2 bits (147), Expect = 5e-09
Identities = 113/544 (20%), Positives = 176/544 (32%), Gaps = 67/544 (12%)
Query: 381 PRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPA 440
P+ P P P + P +P + P +P+ + P PA
Sbjct: 440 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 499
Query: 441 VGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKIS 500
P + P+P + P PT++ S P T+ P +P +PK
Sbjct: 500 PTTPKEPAPTTTKEPSPTTPKEP-------APTTTKSAPTTTKEPAPTTTKSAPTTPK-E 551
Query: 501 LAPTDVKE---LSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPS 557
+PT KE + KEP T P++ A K P ++ + K
Sbjct: 552 PSPTTTKEPAPTTPKEPAPT-TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP 610
Query: 558 SSPENSLDPFPPRILKEEPK---GKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAP 614
++P+ + P ++ P+ E T E + + + +E P
Sbjct: 611 TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPK 670
Query: 615 SGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGP--VAEQVKKSTLNPNAKEFNPTKPL 672
+ P++P P P + P E P A K T KE PT P
Sbjct: 671 AAAPNTPKEPAPTTPKE----PAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK 726
Query: 673 LSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYP 732
K + T+ P T +T P P G A P+ P P
Sbjct: 727 KPAPKELAPTTTKEP-TSTTCDKPA-----------------PTTPKGTAPTTPK-EPAP 767
Query: 733 VSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLV---AATPYSSYIP 789
+ P KG+ P + +PA P A P +T P
Sbjct: 768 TTPKEPAP----TTPKGTAP---TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAP 820
Query: 790 YNPQQ----FPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSS---STPQY 842
P++ P +PA P P+ P P S T+ P I S STP+
Sbjct: 821 TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 880
Query: 843 PSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTG--------SQPQSQHAAPSPV 894
+ +PTP+AL + + A +P+ TT + P++ AAP
Sbjct: 881 --SAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT 938
Query: 895 QHQA 898
+ A
Sbjct: 939 KETA 942
Score = 45.4 bits (106), Expect = 3e-04
Identities = 127/640 (19%), Positives = 199/640 (31%), Gaps = 62/640 (9%)
Query: 432 ETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGS 491
E P P + PP S S + P+PP S +T S
Sbjct: 106 EVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQE 165
Query: 492 ISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGA- 550
S +S S + T K S+K E Q+ ++ ++ + + + G+
Sbjct: 166 SSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSG 225
Query: 551 ----QFKLQP--SSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVS 604
FK+ +S+ +++ P+I +P + + S +K +V
Sbjct: 226 LDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVE 285
Query: 605 DKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAK 664
KE + T+G E+ +Q+ + K KD P ++ + K T P A
Sbjct: 286 TKETTTTNKQTS-TDGKEKTTSAKETQS------IEKTSAKDLAPTSKVLAKPT--PKA- 335
Query: 665 EFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYIS------------ 712
E P L+ K TPT+P +TP P T +S +P+ +
Sbjct: 336 ETTTKGPALTTPKEP-TPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPK 394
Query: 713 -YIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAA 771
P PA P+ P P + P P + +PA P A
Sbjct: 395 EPAPTTTKEPAPTTPK-EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP 453
Query: 772 AAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHP 831
P TP + P + P +P P +P AP P T
Sbjct: 454 TTPKEP----TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKP--APTTPKEPAPTTPKEPA 507
Query: 832 QAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHA----HQPQPATTPTGSQPQSQ 887
+P P PT T + P T A +P P TT + +
Sbjct: 508 PTTTKEPSPTTPKEPAPTTTKSAPTTTKE-PAPTTTKSAPTTPKEPSPTTTKEPAPTTPK 566
Query: 888 HAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGT---PPSLPPGPSAQSPQSSFPQPAA 944
AP+ + A P +P A T T P+ P P+ +P+ + P
Sbjct: 567 EPAPTTPKKPAPTTPK----EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAP---- 618
Query: 945 VYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHG-GPPQG 1003
P T A A P AP P+ P+ P+
Sbjct: 619 -------TTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKA 671
Query: 1004 AVPQSGVPALSASTPSPYPYIGHPQVQSHPSQQLPFHPPG 1043
A P + + P P + P + P P G
Sbjct: 672 AAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG 711
Score = 45.1 bits (105), Expect = 4e-04
Identities = 73/315 (23%), Positives = 110/315 (34%), Gaps = 59/315 (18%)
Query: 405 PSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPE 464
P+ +PK P A T + P+ TS P P + P +PK AP P
Sbjct: 789 PAPTTPKKPAPKELAPTTTKG---PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT 845
Query: 465 PPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPT-DVKELSTKEPGRTLEPQEL 523
P TS S P T+ S ++P++S PT E S KEPG P
Sbjct: 846 TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPG---VPTTK 902
Query: 524 ARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEV 583
A K + + +LR ++PE + P++ KE EK
Sbjct: 903 TPAATKPEMTTTAKDKTTERDLR-----------TTPETT--TAAPKMTKETATTTEKTT 949
Query: 584 DGLLTSEPMGSPVSSKTESVSDKEDKP---------PLAPSGGT-----------EGPEQ 623
+ +T+ +++ S + ++ P LAP T PE+
Sbjct: 950 ESKITA------TTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEE 1003
Query: 624 PPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTP- 682
P T S K P ++ K+ P + + T P + K+T TP
Sbjct: 1004 TAKPKDRATNS----------KATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPR 1053
Query: 683 --TSPGPRTHSTPSI 695
TS P + T I
Sbjct: 1054 KMTSTMPELNPTSRI 1068
>gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
sapiens]
Length = 1858
Score = 70.5 bits (171), Expect = 8e-12
Identities = 110/439 (25%), Positives = 150/439 (34%), Gaps = 72/439 (16%)
Query: 651 AEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQY 710
+EQ+ + + K P P L +STP +P + +P P G Y P +
Sbjct: 1425 SEQLSQKLPSVPTKLHCPPSPHLENPPKSSTPHTPVQHGYLSPKPPSQQLGSP--YRPHH 1482
Query: 711 ISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQA 770
S PQ+ G + PQ YP + ++P + G+L Q A+ Q
Sbjct: 1483 -SQSPQV--GTPQREPQRNFYPAAQNLPANT--QQATSGTLFTQTPSGQSSATYSQFNQQ 1537
Query: 771 A--AAAGPPLVAATPYSSYIP----------YNP----------------QQFPGQPAMM 802
+ + A PP P SSY YN Q PG +
Sbjct: 1538 SLNSTAPPPPPPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQ 1597
Query: 803 QPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYP 862
H+ + F P NP + H Q + P P P P + S+
Sbjct: 1598 TVPGHHVTPGHFLP--SQNPTI-----HHQTAAAVVPPPPPPPPAPGPHLVQQP--NSHQ 1648
Query: 863 HHATQLHAHQPQPATTPTGSQPQSQHAA---------PSPVQHQAGQAPHLGSGQPQQNL 913
H+ H P A TP GS SQ A P P H PH +G
Sbjct: 1649 QHSVA-HVVGPVHAVTP-GSHIHSQTAGHHLPPPPPPPGPAPHHH-PPPHPSTGLQGLQA 1705
Query: 914 YHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHH--QQLPHGFTNMAHVTQAHVQTG 971
H + PP PP P S +S + A+HH Q P F + AH T +
Sbjct: 1706 QHQHVVNSAPPP-PPPPPPSSVLASGHHTTSAQALHHPPHQGPPLFPSSAHPTVPPYPSQ 1764
Query: 972 ITAAPPPHPGAPHPPQVMLLHPPQSHGGP---PQGAVPQSGVPALSASTPSPYP------ 1022
T PG H P H P GP PQG + +P +AS P+P
Sbjct: 1765 ATHHTTLGPGPQHQPSGTGPHCPLPVTGPHLQPQG---PNSIPTPTASGFCPHPGSVALP 1821
Query: 1023 -YIGHPQVQSHPSQQLPFH 1040
+ PQ S Q+P H
Sbjct: 1822 HGVQGPQQASPVPGQIPIH 1840
Score = 60.1 bits (144), Expect = 1e-08
Identities = 136/590 (23%), Positives = 205/590 (34%), Gaps = 109/590 (18%)
Query: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASC---PEPPIGSAVPTSSAS 477
T PS S T PP +M P SP S PA P+P S V S A
Sbjct: 1335 TNECPSPDTSQNTCKSPP----KMSKPGSPGSVIPAQAHGKIFTKPDPQWDSTVSASEAE 1390
Query: 478 --IPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQN 535
+ + + + + + + A K T V+ S+++ + L P L+N
Sbjct: 1391 NGVHLKTELQQKQLSNNNQALSKNHPPQTHVRN-SSEQLSQKLPSVPTKLHCPPSPHLEN 1449
Query: 536 EQKRFQLEE------------LRKFGAQFKLQPSSSPENSLDPFPPR-----ILKEEPKG 578
K ++ G+ ++ S SP+ P+ + P
Sbjct: 1450 PPKSSTPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFYPAAQNLPAN 1509
Query: 579 KEKEVDG-LLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQT---GS 634
++ G L T P G SS T S +++ S + P PPPP PS +
Sbjct: 1510 TQQATSGTLFTQTPSGQ--SSATYSQFNQQ-------SLNSTAPPPPPPPPPSSSYYQNQ 1560
Query: 635 PPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPS 694
P + ++ +G +++Q T PN ++ +TS T PG H TP
Sbjct: 1561 QPSANFQNYNQLKGSLSQQT-VFTSGPNQ----------ALPGTTSQQTVPG--HHVTPG 1607
Query: 695 IPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVS---NSVPGQQGKYRGAK--G 749
L + ++ + +P P P + P S +SV G
Sbjct: 1608 -HFLPSQNPTIHHQTAAAVVPPPPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGS 1666
Query: 750 SLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYP 809
+ Q + H P PP GP P+ P+ G A Q + +
Sbjct: 1667 HIHSQTAGHHLPPPPPP-------PGP-----APHHHPPPHPSTGLQGLQAQHQHVVNSA 1714
Query: 810 SQPVFAPMLQSNPRMLTSGSHPQAIVS------SSTPQYPSAEQPT--PQALYATVHQSY 861
P P S +L SG H + + P +PS+ PT P AT H +
Sbjct: 1715 PPPPPPPPPSS---VLASGHHTTSAQALHHPPHQGPPLFPSSAHPTVPPYPSQATHHTTL 1771
Query: 862 ----PHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPG 917
H + H P P T P QPQ ++ P+P +G PH GS
Sbjct: 1772 GPGPQHQPSGTGPHCPLPVTGP-HLQPQGPNSIPTPT--ASGFCPHPGS----------- 1817
Query: 918 ALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAH 967
+LP G Q PQ + P P + IH Q+P F N H + H
Sbjct: 1818 ------VALPHG--VQGPQQASPVPGQI-PIHRAQVPPTFQNNYHGSGWH 1858
Score = 40.0 bits (92), Expect = 0.011
Identities = 37/151 (24%), Positives = 54/151 (35%), Gaps = 17/151 (11%)
Query: 340 PSLASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEAR 399
PS G + Q + P G S P + P + HH ++ GPG + +
Sbjct: 1723 PSSVLASGHHTTSAQALHHPPHQGPPLFPS-SAHPTVPPYPSQATHH---TTLGPGPQHQ 1778
Query: 400 GINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPIS 459
PS P P+ G P +P G S+P P A G + P A P +
Sbjct: 1779 -----PSGTGPHCPLPVTG------PHLQPQGPNSIPTPTASG--FCPHPGSVALPHGVQ 1825
Query: 460 ASCPEPPIGSAVPTSSASIPVTSSVSDPGVG 490
P+ +P A +P T + G G
Sbjct: 1826 GPQQASPVPGQIPIHRAQVPPTFQNNYHGSG 1856
>gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
sapiens]
Length = 1858
Score = 70.5 bits (171), Expect = 8e-12
Identities = 110/439 (25%), Positives = 150/439 (34%), Gaps = 72/439 (16%)
Query: 651 AEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQY 710
+EQ+ + + K P P L +STP +P + +P P G Y P +
Sbjct: 1425 SEQLSQKLPSVPTKLHCPPSPHLENPPKSSTPHTPVQHGYLSPKPPSQQLGSP--YRPHH 1482
Query: 711 ISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQA 770
S PQ+ G + PQ YP + ++P + G+L Q A+ Q
Sbjct: 1483 -SQSPQV--GTPQREPQRNFYPAAQNLPANT--QQATSGTLFTQTPSGQSSATYSQFNQQ 1537
Query: 771 A--AAAGPPLVAATPYSSYIP----------YNP----------------QQFPGQPAMM 802
+ + A PP P SSY YN Q PG +
Sbjct: 1538 SLNSTAPPPPPPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQ 1597
Query: 803 QPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYP 862
H+ + F P NP + H Q + P P P P + S+
Sbjct: 1598 TVPGHHVTPGHFLP--SQNPTI-----HHQTAAAVVPPPPPPPPAPGPHLVQQP--NSHQ 1648
Query: 863 HHATQLHAHQPQPATTPTGSQPQSQHAA---------PSPVQHQAGQAPHLGSGQPQQNL 913
H+ H P A TP GS SQ A P P H PH +G
Sbjct: 1649 QHSVA-HVVGPVHAVTP-GSHIHSQTAGHHLPPPPPPPGPAPHHH-PPPHPSTGLQGLQA 1705
Query: 914 YHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHH--QQLPHGFTNMAHVTQAHVQTG 971
H + PP PP P S +S + A+HH Q P F + AH T +
Sbjct: 1706 QHQHVVNSAPPP-PPPPPPSSVLASGHHTTSAQALHHPPHQGPPLFPSSAHPTVPPYPSQ 1764
Query: 972 ITAAPPPHPGAPHPPQVMLLHPPQSHGGP---PQGAVPQSGVPALSASTPSPYP------ 1022
T PG H P H P GP PQG + +P +AS P+P
Sbjct: 1765 ATHHTTLGPGPQHQPSGTGPHCPLPVTGPHLQPQG---PNSIPTPTASGFCPHPGSVALP 1821
Query: 1023 -YIGHPQVQSHPSQQLPFH 1040
+ PQ S Q+P H
Sbjct: 1822 HGVQGPQQASPVPGQIPIH 1840
Score = 60.1 bits (144), Expect = 1e-08
Identities = 136/590 (23%), Positives = 205/590 (34%), Gaps = 109/590 (18%)
Query: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASC---PEPPIGSAVPTSSAS 477
T PS S T PP +M P SP S PA P+P S V S A
Sbjct: 1335 TNECPSPDTSQNTCKSPP----KMSKPGSPGSVIPAQAHGKIFTKPDPQWDSTVSASEAE 1390
Query: 478 --IPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQN 535
+ + + + + + + A K T V+ S+++ + L P L+N
Sbjct: 1391 NGVHLKTELQQKQLSNNNQALSKNHPPQTHVRN-SSEQLSQKLPSVPTKLHCPPSPHLEN 1449
Query: 536 EQKRFQLEE------------LRKFGAQFKLQPSSSPENSLDPFPPR-----ILKEEPKG 578
K ++ G+ ++ S SP+ P+ + P
Sbjct: 1450 PPKSSTPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFYPAAQNLPAN 1509
Query: 579 KEKEVDG-LLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQT---GS 634
++ G L T P G SS T S +++ S + P PPPP PS +
Sbjct: 1510 TQQATSGTLFTQTPSGQ--SSATYSQFNQQ-------SLNSTAPPPPPPPPPSSSYYQNQ 1560
Query: 635 PPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPS 694
P + ++ +G +++Q T PN ++ +TS T PG H TP
Sbjct: 1561 QPSANFQNYNQLKGSLSQQT-VFTSGPNQ----------ALPGTTSQQTVPG--HHVTPG 1607
Query: 695 IPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVS---NSVPGQQGKYRGAK--G 749
L + ++ + +P P P + P S +SV G
Sbjct: 1608 -HFLPSQNPTIHHQTAAAVVPPPPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGS 1666
Query: 750 SLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYP 809
+ Q + H P PP GP P+ P+ G A Q + +
Sbjct: 1667 HIHSQTAGHHLPPPPPP-------PGP-----APHHHPPPHPSTGLQGLQAQHQHVVNSA 1714
Query: 810 SQPVFAPMLQSNPRMLTSGSHPQAIVS------SSTPQYPSAEQPT--PQALYATVHQSY 861
P P S +L SG H + + P +PS+ PT P AT H +
Sbjct: 1715 PPPPPPPPPSS---VLASGHHTTSAQALHHPPHQGPPLFPSSAHPTVPPYPSQATHHTTL 1771
Query: 862 ----PHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPG 917
H + H P P T P QPQ ++ P+P +G PH GS
Sbjct: 1772 GPGPQHQPSGTGPHCPLPVTGP-HLQPQGPNSIPTPT--ASGFCPHPGS----------- 1817
Query: 918 ALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAH 967
+LP G Q PQ + P P + IH Q+P F N H + H
Sbjct: 1818 ------VALPHG--VQGPQQASPVPGQI-PIHRAQVPPTFQNNYHGSGWH 1858
Score = 40.0 bits (92), Expect = 0.011
Identities = 37/151 (24%), Positives = 54/151 (35%), Gaps = 17/151 (11%)
Query: 340 PSLASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEAR 399
PS G + Q + P G S P + P + HH ++ GPG + +
Sbjct: 1723 PSSVLASGHHTTSAQALHHPPHQGPPLFPS-SAHPTVPPYPSQATHH---TTLGPGPQHQ 1778
Query: 400 GINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPIS 459
PS P P+ G P +P G S+P P A G + P A P +
Sbjct: 1779 -----PSGTGPHCPLPVTG------PHLQPQGPNSIPTPTASG--FCPHPGSVALPHGVQ 1825
Query: 460 ASCPEPPIGSAVPTSSASIPVTSSVSDPGVG 490
P+ +P A +P T + G G
Sbjct: 1826 GPQQASPVPGQIPIHRAQVPPTFQNNYHGSG 1856
>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
Length = 1970
Score = 69.3 bits (168), Expect = 2e-11
Identities = 84/348 (24%), Positives = 123/348 (35%), Gaps = 22/348 (6%)
Query: 611 PLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTK 670
P S G+ GP P P P SP + P + + +P + ++PT
Sbjct: 1567 PTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTS 1626
Query: 671 PLLSVNKSTSTPTSP--GPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQM 728
P S +PTSP P + S + S YSP SY P P+
Sbjct: 1627 PSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP---TSPSYSPTSP 1683
Query: 729 YPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPAS------APPMMQAAAAAGPPLVAAT 782
P S S Y S P S + P S +P + + P + +
Sbjct: 1684 SYSPTSPSYSPTSPSYSPTSPSYSP-TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS 1742
Query: 783 PYS-SYIPYNPQQFPGQPAMMQPMAHY-PSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840
P S +Y P +P P P+ Y P+ P + P + S S S ++P
Sbjct: 1743 PTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSP 1802
Query: 841 QY-PSAEQPTPQALYATVHQSYPHHATQLHAHQP-QPATTPTGSQPQSQHAAPSPVQHQA 898
Y PS+ + TPQ+ T S P ++ ++ P P TPT P ++P
Sbjct: 1803 SYSPSSPRYTPQS--PTYTPSSPSYSPSSPSYSPTSPKYTPT--SPSYSPSSPEYTPTSP 1858
Query: 899 GQAPHLGSGQPQQNLYHPGALTGTP--PSLPPGPSAQSPQSSFPQPAA 944
+P P Y P + T +P P P SP S P +
Sbjct: 1859 KYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTS 1906
Score = 65.5 bits (158), Expect = 3e-10
Identities = 117/476 (24%), Positives = 157/476 (32%), Gaps = 64/476 (13%)
Query: 391 SPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPS-------GETSVPPPPAVGR 443
SP GS G+ G + SP A G SP+ P+ G +S P G
Sbjct: 1532 SPSVGS---GMTPGAAGFSPSAASDASGFSPGYSPAWSPTPGSPGSPGPSSPYIPSPGGA 1588
Query: 444 MYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAP 503
M P SP S A P S P S PTS + P + S S P + SP SP S +P
Sbjct: 1589 MSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYS-PTSPNYSPTSP--SYSP 1645
Query: 504 TDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPEN- 562
T T P P PS SP +
Sbjct: 1646 TSPSYSPTSPSYSPTSPSYSPTSPSYSP----------------------TSPSYSPTSP 1683
Query: 563 SLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSS--KTESVSDKEDKPPLAPSGGTEG 620
S P P P TS P SP S S S P +P+ +
Sbjct: 1684 SYSPTSPSYSPTSPSYSPTSPSYSPTS-PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS 1742
Query: 621 PEQP--PPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN--PNAKEFNPTKPLLSVN 676
P P P P+ T + P P + ++ N P + ++PT P S
Sbjct: 1743 PTSPNYSPTSPNYTPTSP---------SYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPT 1793
Query: 677 KSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNS 736
+ +PTSP +PS P T QS Y+P SY P P+ P S S
Sbjct: 1794 SPSYSPTSPS----YSPSSPRYTP-QSPTYTPSSPSYSPS---SPSYSPTSPKYTPTSPS 1845
Query: 737 VPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYS-SYIPYNPQQF 795
+Y P S ++ P S P + P +P S +Y P +P
Sbjct: 1846 YSPSSPEYTPTSPKYSP-TSPKYSPTS-PKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYT 1903
Query: 796 PGQPAMMQPMAHY-PSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTP 850
P P Y P+ P ++P + GS +P P+ +P
Sbjct: 1904 PTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSPTSPTYSLTSP 1959
Score = 57.8 bits (138), Expect = 5e-08
Identities = 87/358 (24%), Positives = 121/358 (33%), Gaps = 31/358 (8%)
Query: 338 ESPSLASREGKYIPL-----PQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNS-S 391
+SPS + Y P P P +S P S P P + S S
Sbjct: 1611 QSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPS 1670
Query: 392 PGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPK 451
P S + + + P + + +SPS P+ + P P+ P SP
Sbjct: 1671 YSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPT 1730
Query: 452 SAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELST 511
S + +P S S P + PTS P + S S P S SP SP + PT T
Sbjct: 1731 SPSYSPTSPSY-SPTSPNYSPTSPNYTPTSPSYS-PTSPSYSPTSPNYT--PTSPNYSPT 1786
Query: 512 KEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRI 571
P + P R+ + + PSS S P P+
Sbjct: 1787 SPSYSPTSPS----YSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSP---SYSPTSPKY 1839
Query: 572 LKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQ 631
P + TS P SP S K S P +P+ T P P S
Sbjct: 1840 TPTSPSYSPSSPEYTPTS-PKYSPTSPKYSPTS-----PKYSPTSPTYSPTTPKYSPTSP 1893
Query: 632 TGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNK---STSTPTSPG 686
T SP + P + T +P + +++PT P S ST +PTSPG
Sbjct: 1894 TYSPTSPVYTPTSPKYSPTSP-----TYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPG 1946
Score = 40.4 bits (93), Expect = 0.009
Identities = 72/324 (22%), Positives = 103/324 (31%), Gaps = 17/324 (5%)
Query: 339 SPSLASREGKYIPL-----PQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNS-SP 392
SPS + Y P P P +S P S P P + S S
Sbjct: 1647 SPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSY 1706
Query: 393 GPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKS 452
P S + + + P + + +SPS P+ P P P SP S
Sbjct: 1707 SPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTS 1766
Query: 453 AAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKIS-LAPTDVKELST 511
+ +P S + P + PTS + P + S S P S SP+SP+ + +PT +
Sbjct: 1767 PSYSPTSPNYT-PTSPNYSPTSPSYSPTSPSYS-PTSPSYSPSSPRYTPQSPTYTPSSPS 1824
Query: 512 KEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDP-FPPR 570
P + P + + K P+S + P + P
Sbjct: 1825 YSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPT 1884
Query: 571 ILKEEPKGKEKEVDGLL--TSEPMGSPVSSKTESVSDKEDKP-----PLAPSGGTEGPEQ 623
K P + + P SP S S K P +P G T P
Sbjct: 1885 TPKYSPTSPTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTS 1944
Query: 624 PPPPCPSQTGSPPVGLIKGEDKDE 647
P S T S I +D DE
Sbjct: 1945 PGYSPTSPTYSLTSPAISPDDSDE 1968
Score = 33.9 bits (76), Expect = 0.82
Identities = 52/261 (19%), Positives = 90/261 (34%), Gaps = 22/261 (8%)
Query: 776 PPLVAATPYSSYIPYNPQQFPGQPAMMQP--MAHYPSQPVFAPMLQSNPRMLTSGSHPQA 833
P L AA P + P G M P P+ ++P + S +G P A
Sbjct: 1491 PGLGAAGPTGMFFGSAPSPMGGISPAMTPWNQGATPAYGAWSPSVGSGMTPGAAGFSPSA 1550
Query: 834 IVSSS------------TPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTG 881
+S TP P + P+ + + P ++ A++P+ +P G
Sbjct: 1551 ASDASGFSPGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPR---SPGG 1607
Query: 882 SQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQ 941
PQS +P+ + + +P P + P +P P PS S+
Sbjct: 1608 YTPQSPSYSPTSPSY-SPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP 1666
Query: 942 PAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPP 1001
+ Y+ + + + ++ T + +P +P P P S P
Sbjct: 1667 TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPS 1726
Query: 1002 QGAVPQSGVPALSASTPSPYP 1022
P S P+ S ++PS P
Sbjct: 1727 YS--PTS--PSYSPTSPSYSP 1743
>gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]
Length = 2089
Score = 68.6 bits (166), Expect = 3e-11
Identities = 170/859 (19%), Positives = 291/859 (33%), Gaps = 130/859 (15%)
Query: 278 TVPLEKDNSEEFRQRELRAAQLAREIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGR 337
++ +E + SEE ++++++ L + R E D EE+ + + + R
Sbjct: 889 SLKVEIETSEEIQEKQVQKQTLPSKAFEREVERPVANRECDPAELEEKVPKVILERDTQR 948
Query: 338 ESPSLASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLP-PRGPHHLDNSSP-GPG 395
P S++ K Q P GV G PG +S P P G SP P
Sbjct: 949 GEPEGGSQDQK----GQASSPTPEPGV----GAGDLPGPTSAPVPSGSQSGGRGSPVSPR 1000
Query: 396 SEARGINGGPSRMSPKAQRPLRGAKTLS-------------------SPSNRPSGETS-- 434
+G+ + KA R +R A+ +S +P +P S
Sbjct: 1001 RHQKGLLNCKMPPAEKASR-IRAAEKVSRGDQESPDACLPPTVPEAPAPPQKPLNSQSQK 1059
Query: 435 -VPPPPAVGRMYPPRSP----------KSAAPAPISASC----PEPPIGSAVPTSSASIP 479
+ PPP + + P P + A AP+S+ P+P I + + P
Sbjct: 1060 HLAPPPLLSPLLPSIKPTVRKTRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPFP 1119
Query: 480 VTSSVSDP--GVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQ 537
TS+ +P + P +PK + T + + + +T EP + P LQ
Sbjct: 1120 ATSAAPEPHPSTSTAQPVTPKPTSQAT--RSRTNRSSVKTPEP-----VVPTAPELQPST 1172
Query: 538 KRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVS 597
Q + + S S + + P L+ +P D +TSEP
Sbjct: 1173 STDQPVTSEPTSQVTRGRKSRSSVKTPETVVPTALELQPS---TSTDRPVTSEPTSQATR 1229
Query: 598 SKTESVSDKEDKP------PLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVA 651
+ S K +P L PS T+ P P + G +K + P A
Sbjct: 1230 GRKNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTYQATRGRKNRSSVKTPEPVV-PTA 1288
Query: 652 EQVKKSTLN-------PNAKEFN---------------PTKPLLSVNKSTSTPTSPGPRT 689
+++ ST P ++ PT P L ++ ST P +P P +
Sbjct: 1289 PELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTS 1348
Query: 690 HSTPSIPVLTAGQSGLYSPQ-YISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRG-- 746
+T S S + +P+ + P++ + + P + P P S + G++ + G
Sbjct: 1349 RTTRS----RTNMSSVKNPESTVPIAPELPPSTSTEQP-VTPEPTSRATRGRKNRSSGKT 1403
Query: 747 ------AKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPG--- 797
L P S QP + P QA TP + +P P+ P
Sbjct: 1404 PETLVPTAPKLEPSTSTD-QPVTPEPTSQATRGRTNRSSVKTP-ETVVPTAPELQPSTST 1461
Query: 798 -QPAMMQPMAH-------YPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQ-- 847
QP +P + S ++ + P + S S Q + S T + +
Sbjct: 1462 DQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTTRGRKNR 1521
Query: 848 ---PTPQALYATVHQSYPHHATQLHAHQP-QPATTPTGSQPQSQHAAPSPVQHQAGQAPH 903
TP+ + + P +T QP P T ++ ++ ++ + AP
Sbjct: 1522 SSVKTPETVVPAAPELQPSTSTD----QPVTPEPTSRATRGRTNRSSVKTPESIVPIAPE 1577
Query: 904 LGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHV 963
L + L P + S ++P+ P + P +
Sbjct: 1578 LQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPVVPTAPEPHPTTSTDQPVTPKLTSRA 1637
Query: 964 TQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSG-VPALSASTPSPYP 1022
T+ +T ++ P P P + P P A+ Q G L +ST P
Sbjct: 1638 TRR--KTNRSSVKTPKPVEPAASDLEPFTPTDQSVTPE--AIAQGGQSKTLRSSTVRAMP 1693
Query: 1023 YIGHPQVQSHPSQQLPFHP 1041
P+ QS + P P
Sbjct: 1694 VPTTPEFQSPVTTDQPISP 1712
>gi|151301154 mucin 6, gastric [Homo sapiens]
Length = 2439
Score = 68.2 bits (165), Expect = 4e-11
Identities = 151/668 (22%), Positives = 215/668 (32%), Gaps = 116/668 (17%)
Query: 424 SPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIG---SAVPTSSASIP- 479
S ++ P+ T P PA P + P P +A P+ G +A S+A+ P
Sbjct: 1241 SSNHTPASPTQTPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPT 1300
Query: 480 VTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKR 539
VT + + + SPA+ + + T RT +G P L
Sbjct: 1301 VTQATTRATASTASPATTSTAQSTT-----------RTTMTLPTPATSGTSPTLPKSTN- 1348
Query: 540 FQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSK 599
+EL A P +P ++ P P+ +P +
Sbjct: 1349 ---QELPGTTATQTTGPRPTPASTTGPTTPQ-----------------PGQPTRPTATET 1388
Query: 600 TESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTL 659
T++ + E P P T P P PS TG PV P ++TL
Sbjct: 1389 TQTRTTTEYTTPQTPH-TTHSPPTAGSPVPS-TG--PVTATSFHATTTYPTPSH-PETTL 1443
Query: 660 NPNAKEFN-------------PTKPLLSV---NKSTSTPTSPGP-------RTHSTPSIP 696
+ F+ PT ++ N S T T P P TH+ P I
Sbjct: 1444 PTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPIT 1503
Query: 697 VLTAGQSGLYSPQYISYIP-QIHMGPA---------VQAPQMYPYPVSNSVPGQQGKYRG 746
T+G S +S + P +H + + P P S
Sbjct: 1504 PTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNS 1563
Query: 747 AKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMA 806
A S PP H P P ++ GP + AT + + Y P P P
Sbjct: 1564 ATSSRPPPPFTTHSP---PTGSSPFSSTGP--MTATSFKTTTTY---PTPSHPQTTLP-T 1614
Query: 807 HYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHAT 866
H P P ++ + + + +H Q S+S P+ P P L AT
Sbjct: 1615 HVP--PFSTSLVTPSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKAT---------G 1663
Query: 867 QLHAHQPQPATTPTGSQPQS--QHAAPSPVQHQAGQAPH--LGSGQPQQNLYHPGALTGT 922
H TT SQ S A S H + H + N+ TGT
Sbjct: 1664 STHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGT 1723
Query: 923 PPSLPPGPSAQSPQSSFPQPAAVYAIH-HQQLPH----GFTNMAHVTQAHVQTGITAAPP 977
PP +SSF ++H H H T+ +T H TG T P
Sbjct: 1724 PPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTG-TRTPV 1782
Query: 978 PHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSG---VPALSASTPSPYPYIGHPQVQSHPS 1034
H + + L P + PP G P S V A S T + YP SHP
Sbjct: 1783 AHTTSATSSR---LPTPFTTHSPPTGTTPISSTGPVTATSFQTTTTYP------TPSHPH 1833
Query: 1035 QQLPFHPP 1042
LP H P
Sbjct: 1834 TTLPTHVP 1841
Score = 66.2 bits (160), Expect = 1e-10
Identities = 155/741 (20%), Positives = 230/741 (31%), Gaps = 154/741 (20%)
Query: 374 PGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGET 433
PG ++ GP S+ GP + G P+ R T +P S T
Sbjct: 1352 PGTTATQTTGPRPTPASTTGPTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPT 1411
Query: 434 SVPPPPAVGRM----------YP-PRSPKSAAPA---PISASCPEPPIGSAVPTSSASIP 479
+ P P+ G + YP P P++ P P S S P + + + A +
Sbjct: 1412 AGSPVPSTGPVTATSFHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMA 1471
Query: 480 VTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKR 539
++S G+I P PT +K + + P G
Sbjct: 1472 TSASNHSAPTGTIPP--------PTTLKATGSTHTAPPITP--------TTSGTSQAHSS 1515
Query: 540 FQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSK 599
F S + P + EV T+ +P S++
Sbjct: 1516 F----------------------STNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTR 1553
Query: 600 TESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPV-AEQVKKST 658
T + P T PP P T SPP G GP+ A K +T
Sbjct: 1554 TRT-----------PVAHTNSATSSRPPPPFTTHSPPTG--SSPFSSTGPMTATSFKTTT 1600
Query: 659 LNPNAKEFNPTKPLLSVNKSTS---------------------------TPTSPGP---- 687
P T P STS T T P P
Sbjct: 1601 TYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLK 1660
Query: 688 ---RTHSTPSIPVLTAGQS--------GLYSPQYISYIPQIHMGPA--VQAPQMYPYPVS 734
TH+ P++ + T+G S S S+ H A + P P S
Sbjct: 1661 ATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTS 1720
Query: 735 NSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQ 794
P G S RS ++ + ++ P V +T +S P +
Sbjct: 1721 TGTPPMTVTTSGTSQS----RSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTST 1776
Query: 795 FPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALY 854
P A P P +P T+ V++++ Q + PTP +
Sbjct: 1777 GTRTPVAHTTSATSSRLP--TPFTTHSPPTGTTPISSTGPVTATSFQ-TTTTYPTPSHPH 1833
Query: 855 ATVHQSYPHHATQLHAHQPQPATTPTGSQ---PQSQHAAPSPVQHQAGQAPHLGSGQPQQ 911
T+ P +T L PT +Q S H+ P+ G+ P
Sbjct: 1834 TTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPT------------GTIPPPT 1881
Query: 912 NLYHPGALTGTPPSLP-PGPSAQSPQS------SFPQPAAVYAIHHQQLPHGFTNMAHVT 964
+ G+ PP P ++QSP S S P + HH ++ T+ ++T
Sbjct: 1882 TIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTP--TSTTNIT 1939
Query: 965 QAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSG---VPALSASTPSPY 1021
H TG T P H + + L P + PP G+ P S + A S T + Y
Sbjct: 1940 PKHTSTG-TRTPVAHTTSASSSR---LPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTY 1995
Query: 1022 PYIGHPQVQSHPSQQLPFHPP 1042
P SHP LP H P
Sbjct: 1996 P------TPSHPQTTLPTHVP 2010
Score = 63.5 bits (153), Expect = 1e-09
Identities = 151/679 (22%), Positives = 225/679 (33%), Gaps = 86/679 (12%)
Query: 405 PSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPP-------AVGRM----------YP- 446
P+ S + + P+ A T S+ S+RP + PP + G M YP
Sbjct: 1547 PNPTSTRTRTPV--AHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPT 1604
Query: 447 PRSPKSAAPA---PISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAP 503
P P++ P P S S P + + + A + ++S+ G+I P + +
Sbjct: 1605 PSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGS 1664
Query: 504 TDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENS 563
T T T + A L + E A + +P +
Sbjct: 1665 THTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAE-----ATSTSTTNITPNPT 1719
Query: 564 LDPFPPRILKEEPKGKEK-EVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPE 622
PP + + + TS + S SS + P+ + G
Sbjct: 1720 STGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTR 1779
Query: 623 QPPP----------PCPSQTGSPPVGLIKGEDKDEGPV-AEQVKKSTLNPNAKEFNPTKP 671
P P P T SPP G GPV A + +T P + T P
Sbjct: 1780 TPVAHTTSATSSRLPTPFTTHSPPTGTT--PISSTGPVTATSFQTTTTYPTPSHPHTTLP 1837
Query: 672 LLSVNKSTSTPTSPGPRTHSTPSIPVLT--AGQSGLYSPQYISYIPQIHM---GPAVQAP 726
+ STS T P TH T IP T A + ++S + P + G AP
Sbjct: 1838 THVPSFSTSLVT---PSTH-TVIIPTHTQMATSASIHSMPTGTIPPPTTIKATGSTHTAP 1893
Query: 727 QMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAP-------PMMQAAAAAGPPLV 779
M P S SLP S H P P P + P
Sbjct: 1894 PMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTSTGTRTPVAH 1953
Query: 780 AATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSST 839
+ SS +P P P P + + P+ A Q+ T SHPQ + +
Sbjct: 1954 TTSASSSRLP-TPFTTHSPPTGSSPFS--STGPMTATSFQTTTTYPTP-SHPQTTLPTHV 2009
Query: 840 PQY-PSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQA 898
P + S P+ + T H AT H +TPTG+ P + H A
Sbjct: 2010 PPFSTSLVTPSTHTVIITTHTQM---ATSASIH-----STPTGTVPPPTTLKATGSTHTA 2061
Query: 899 GQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFT 958
SG Q H T T S S+ PQ+S +P + + QLPH
Sbjct: 2062 PPMTVTTSGTSQT---HSSFSTATASSSFISSSSWLPQNSSSRPPS--SPITTQLPH--- 2113
Query: 959 NMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTP 1018
+ T ++++ P P A P + + P SH PQ + P G + S P
Sbjct: 2114 LSSATTPVSTTNQLSSSFSPSPSA---PSTVSSYVPSSHSS-PQTSSPSVGTSSSFVSAP 2169
Query: 1019 SPYPYI---GHPQVQSHPS 1034
+ H + +HP+
Sbjct: 2170 VHSTTLSSGSHSSLSTHPT 2188
Score = 43.1 bits (100), Expect = 0.001
Identities = 55/201 (27%), Positives = 79/201 (39%), Gaps = 23/201 (11%)
Query: 331 QRQGSGRESPSLASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNS 390
Q S SPS S Y+P + V SSS P S+ G H ++
Sbjct: 2126 QLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLST 2185
Query: 391 SPGPGSEARGINGGPS-RMSPKAQRPLRGA--KTLSSPSNR----PSGETSVPPPP---- 439
P S ++ P SP A +R T+SSP P +V P P
Sbjct: 2186 HPTTAS----VSASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHL 2241
Query: 440 AVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKI 499
A + P +P++ +AS P S+ T+S S +T+ V G S++ I
Sbjct: 2242 ASSTIAFPSTPRT------TASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGI 2295
Query: 500 SLAPTDVKELSTKEPGRTLEP 520
+P V L+T+ PG TL P
Sbjct: 2296 PTSP--VTNLTTRHPGPTLSP 2314
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.128 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 60,472,220
Number of Sequences: 37866
Number of extensions: 4401726
Number of successful extensions: 51237
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 358
Number of HSP's successfully gapped in prelim test: 2375
Number of HSP's that attempted gapping in prelim test: 22523
Number of HSP's gapped (non-prelim): 21745
length of query: 1044
length of database: 18,247,518
effective HSP length: 112
effective length of query: 932
effective length of database: 14,006,526
effective search space: 13054082232
effective search space used: 13054082232
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.