Search of human proteins with 24430151

Search of human proteins with 24430151

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|24430151 proteasome 26S ATPase subunit 1 [Homo sapiens]
         (440 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|24430151 proteasome 26S ATPase subunit 1 [Homo sapiens]            872   0.0  
gi|169167838 PREDICTED: similar to hCG2002932 [Homo sapiens]          669   0.0  
gi|239748566 PREDICTED: similar to hCG2002932 [Homo sapiens]          669   0.0  
gi|239742549 PREDICTED: hypothetical protein LOC345645 [Homo sap...   669   0.0  
gi|89064750 PREDICTED: similar to proteasome 26S ATPase subunit ...   393   e-109
gi|5729991 proteasome 26S ATPase subunit 4 isoform 1 [Homo sapiens]   393   e-109
gi|24430155 proteasome 26S ATPase subunit 4 isoform 2 [Homo sapi...   384   e-107
gi|24497435 proteasome 26S ATPase subunit 5 [Homo sapiens]            346   2e-95
gi|21361144 proteasome 26S ATPase subunit 3 [Homo sapiens]            346   2e-95
gi|4506209 proteasome 26S ATPase subunit 2 [Homo sapiens]             314   9e-86
gi|195539395 proteasome 26S ATPase subunit 6 [Homo sapiens]           306   2e-83
gi|157671927 spermatogenesis associated 5 [Homo sapiens]              221   1e-57
gi|6005942 valosin-containing protein [Homo sapiens]                  215   7e-56
gi|5802970 AFG3 ATPase family gene 3-like 2 [Homo sapiens]            197   2e-50
gi|153792536 ATPase family, AAA domain containing 2B [Homo sapiens]   191   1e-48
gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]     188   1e-47
gi|229577436 spermatogenesis associated 5-like 1 [Homo sapiens]       177   2e-44
gi|4507173 spastic paraplegia 7 isoform 1 [Homo sapiens]              172   7e-43
gi|45643125 nuclear VCP-like isoform 2 [Homo sapiens]                 170   3e-42
gi|45643123 nuclear VCP-like isoform 1 [Homo sapiens]                 170   3e-42
gi|4505725 peroxin1 [Homo sapiens]                                    169   6e-42
gi|194018488 peroxisomal biogenesis factor 6 [Homo sapiens]           167   1e-41
gi|5901990 katanin p60 subunit A 1 [Homo sapiens]                     161   1e-39
gi|21327685 YME1-like 1 isoform 1 [Homo sapiens]                      160   2e-39
gi|7657689 YME1-like 1 isoform 3 [Homo sapiens]                       160   2e-39
gi|62177112 katanin p60 subunit A-like 1 [Homo sapiens]               156   3e-38
gi|14149767 katanin p60 subunit A-like 1 [Homo sapiens]               156   3e-38
gi|31742536 fidgetin-like 1 [Homo sapiens]                            148   1e-35
gi|112789543 fidgetin-like 1 [Homo sapiens]                           148   1e-35
gi|156564401 vesicle-fusing ATPase [Homo sapiens]                     145   7e-35

>gi|24430151 proteasome 26S ATPase subunit 1 [Homo sapiens]
          Length = 440

 Score =  872 bits (2254), Expect = 0.0
 Identities = 440/440 (100%), Positives = 440/440 (100%)

Query: 1   MGQSQSGGHGPGGGKKDDKDKKKKYEPPVPTRVGKKKKKTKGPDAASKLPLVTPHTQCRL 60
           MGQSQSGGHGPGGGKKDDKDKKKKYEPPVPTRVGKKKKKTKGPDAASKLPLVTPHTQCRL
Sbjct: 1   MGQSQSGGHGPGGGKKDDKDKKKKYEPPVPTRVGKKKKKTKGPDAASKLPLVTPHTQCRL 60

Query: 61  KLLKLERIKDYLLMEEEFIRNQEQMKPLEEKQEEERSKVDDLRGTPMSVGTLEEIIDDNH 120
           KLLKLERIKDYLLMEEEFIRNQEQMKPLEEKQEEERSKVDDLRGTPMSVGTLEEIIDDNH
Sbjct: 61  KLLKLERIKDYLLMEEEFIRNQEQMKPLEEKQEEERSKVDDLRGTPMSVGTLEEIIDDNH 120

Query: 121 AIVSTSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTDPLVTVMKVEKAP 180
           AIVSTSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTDPLVTVMKVEKAP
Sbjct: 121 AIVSTSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTDPLVTVMKVEKAP 180

Query: 181 QETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVA 240
           QETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVA
Sbjct: 181 QETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVA 240

Query: 241 NQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSG 300
           NQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSG
Sbjct: 241 NQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSG 300

Query: 301 GEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKT 360
           GEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKT
Sbjct: 301 GEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKT 360

Query: 361 KKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFK 420
           KKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFK
Sbjct: 361 KKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFK 420

Query: 421 KSKENVLYKKQEGTPEGLYL 440
           KSKENVLYKKQEGTPEGLYL
Sbjct: 421 KSKENVLYKKQEGTPEGLYL 440


>gi|169167838 PREDICTED: similar to hCG2002932 [Homo sapiens]
          Length = 415

 Score =  669 bits (1726), Expect = 0.0
 Identities = 346/412 (83%), Positives = 367/412 (89%), Gaps = 16/412 (3%)

Query: 31  TRVGKKKKKTKGPDAASKLPLVTPHTQCRLKLLKLERIKDYLLMEEEFIRNQEQMKPLEE 90
           TRV +K++KTKG D ASKLPLVT HTQCRLKLLKLERIKDYLLM EEFIRNQEQ+K LEE
Sbjct: 18  TRVAEKEEKTKGQDVASKLPLVTLHTQCRLKLLKLERIKDYLLMVEEFIRNQEQIKLLEE 77

Query: 91  KQEEERSKVDDLRGTPMSVGTLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDLLEPGCSV 150
           KQEE RSKVDDLRGTPMSVG LEEIIDDNHAIVSTSVGSEHY SI+SFV+KDLLEPGCS+
Sbjct: 78  KQEEGRSKVDDLRGTPMSVGNLEEIIDDNHAIVSTSVGSEHYDSIISFVEKDLLEPGCSI 137

Query: 151 LLNHKVHAVIGVLMDDTDPLVTVMKVEKAPQETYADIGGLDNQIQEIKESVELPLTHPEY 210
           LL HKVHAVIGVLMDDT PLVT+MKVEKAPQETY + GGLDNQIQEIKES+ELPL HPEY
Sbjct: 138 LLRHKVHAVIGVLMDDTGPLVTMMKVEKAPQETYVNTGGLDNQIQEIKESMELPLPHPEY 197

Query: 211 YEEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVREL 270
           YEEMG KPPKGVIL GPPGT              ATFLRVVGSELIQKYLGDGPKLVR++
Sbjct: 198 YEEMGTKPPKGVILCGPPGT--------------ATFLRVVGSELIQKYLGDGPKLVRQV 243

Query: 271 FRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTM--LELLNQLDGFDSRGDVKVI 328
           F+VAEEHAPSI+F DEI+AIGTKRYDSNSGGEREIQ+TM  LELLNQL GFDSR DVKVI
Sbjct: 244 FQVAEEHAPSIMFTDEIEAIGTKRYDSNSGGEREIQQTMLELELLNQLGGFDSREDVKVI 303

Query: 329 MATNRIETLDPALIRPGRIDRKIEFPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKD 388
           MAT ++ETLDP LIRPGRID+KIEF LPDEKTKK IFQIHTSRMTLA+DVTLDDLIMAKD
Sbjct: 304 MATKQVETLDPVLIRPGRIDKKIEFHLPDEKTKKHIFQIHTSRMTLANDVTLDDLIMAKD 363

Query: 389 DLSGADIKAICTEAGLMALRERRMKVTNEDFKKSKENVLYKKQEGTPEGLYL 440
           D SGADIKAICTEAGLMALRE RMK TNEDFKKS E+VLYKK EG PEGLYL
Sbjct: 364 DFSGADIKAICTEAGLMALREHRMKATNEDFKKSIESVLYKKHEGIPEGLYL 415


>gi|239748566 PREDICTED: similar to hCG2002932 [Homo sapiens]
          Length = 415

 Score =  669 bits (1726), Expect = 0.0
 Identities = 346/412 (83%), Positives = 367/412 (89%), Gaps = 16/412 (3%)

Query: 31  TRVGKKKKKTKGPDAASKLPLVTPHTQCRLKLLKLERIKDYLLMEEEFIRNQEQMKPLEE 90
           TRV +K++KTKG D ASKLPLVT HTQCRLKLLKLERIKDYLLM EEFIRNQEQ+K LEE
Sbjct: 18  TRVAEKEEKTKGQDVASKLPLVTLHTQCRLKLLKLERIKDYLLMVEEFIRNQEQIKLLEE 77

Query: 91  KQEEERSKVDDLRGTPMSVGTLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDLLEPGCSV 150
           KQEE RSKVDDLRGTPMSVG LEEIIDDNHAIVSTSVGSEHY SI+SFV+KDLLEPGCS+
Sbjct: 78  KQEEGRSKVDDLRGTPMSVGNLEEIIDDNHAIVSTSVGSEHYDSIISFVEKDLLEPGCSI 137

Query: 151 LLNHKVHAVIGVLMDDTDPLVTVMKVEKAPQETYADIGGLDNQIQEIKESVELPLTHPEY 210
           LL HKVHAVIGVLMDDT PLVT+MKVEKAPQETY + GGLDNQIQEIKES+ELPL HPEY
Sbjct: 138 LLRHKVHAVIGVLMDDTGPLVTMMKVEKAPQETYVNTGGLDNQIQEIKESMELPLPHPEY 197

Query: 211 YEEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVREL 270
           YEEMG KPPKGVIL GPPGT              ATFLRVVGSELIQKYLGDGPKLVR++
Sbjct: 198 YEEMGTKPPKGVILCGPPGT--------------ATFLRVVGSELIQKYLGDGPKLVRQV 243

Query: 271 FRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTM--LELLNQLDGFDSRGDVKVI 328
           F+VAEEHAPSI+F DEI+AIGTKRYDSNSGGEREIQ+TM  LELLNQL GFDSR DVKVI
Sbjct: 244 FQVAEEHAPSIMFTDEIEAIGTKRYDSNSGGEREIQQTMLELELLNQLGGFDSREDVKVI 303

Query: 329 MATNRIETLDPALIRPGRIDRKIEFPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKD 388
           MAT ++ETLDP LIRPGRID+KIEF LPDEKTKK IFQIHTSRMTLA+DVTLDDLIMAKD
Sbjct: 304 MATKQVETLDPVLIRPGRIDKKIEFHLPDEKTKKHIFQIHTSRMTLANDVTLDDLIMAKD 363

Query: 389 DLSGADIKAICTEAGLMALRERRMKVTNEDFKKSKENVLYKKQEGTPEGLYL 440
           D SGADIKAICTEAGLMALRE RMK TNEDFKKS E+VLYKK EG PEGLYL
Sbjct: 364 DFSGADIKAICTEAGLMALREHRMKATNEDFKKSIESVLYKKHEGIPEGLYL 415


>gi|239742549 PREDICTED: hypothetical protein LOC345645 [Homo
           sapiens]
          Length = 415

 Score =  669 bits (1726), Expect = 0.0
 Identities = 346/412 (83%), Positives = 367/412 (89%), Gaps = 16/412 (3%)

Query: 31  TRVGKKKKKTKGPDAASKLPLVTPHTQCRLKLLKLERIKDYLLMEEEFIRNQEQMKPLEE 90
           TRV +K++KTKG D ASKLPLVT HTQCRLKLLKLERIKDYLLM EEFIRNQEQ+K LEE
Sbjct: 18  TRVAEKEEKTKGQDVASKLPLVTLHTQCRLKLLKLERIKDYLLMVEEFIRNQEQIKLLEE 77

Query: 91  KQEEERSKVDDLRGTPMSVGTLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDLLEPGCSV 150
           KQEE RSKVDDLRGTPMSVG LEEIIDDNHAIVSTSVGSEHY SI+SFV+KDLLEPGCS+
Sbjct: 78  KQEEGRSKVDDLRGTPMSVGNLEEIIDDNHAIVSTSVGSEHYDSIISFVEKDLLEPGCSI 137

Query: 151 LLNHKVHAVIGVLMDDTDPLVTVMKVEKAPQETYADIGGLDNQIQEIKESVELPLTHPEY 210
           LL HKVHAVIGVLMDDT PLVT+MKVEKAPQETY + GGLDNQIQEIKES+ELPL HPEY
Sbjct: 138 LLRHKVHAVIGVLMDDTGPLVTMMKVEKAPQETYVNTGGLDNQIQEIKESMELPLPHPEY 197

Query: 211 YEEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVREL 270
           YEEMG KPPKGVIL GPPGT              ATFLRVVGSELIQKYLGDGPKLVR++
Sbjct: 198 YEEMGTKPPKGVILCGPPGT--------------ATFLRVVGSELIQKYLGDGPKLVRQV 243

Query: 271 FRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTM--LELLNQLDGFDSRGDVKVI 328
           F+VAEEHAPSI+F DEI+AIGTKRYDSNSGGEREIQ+TM  LELLNQL GFDSR DVKVI
Sbjct: 244 FQVAEEHAPSIMFTDEIEAIGTKRYDSNSGGEREIQQTMLELELLNQLGGFDSREDVKVI 303

Query: 329 MATNRIETLDPALIRPGRIDRKIEFPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKD 388
           MAT ++ETLDP LIRPGRID+KIEF LPDEKTKK IFQIHTSRMTLA+DVTLDDLIMAKD
Sbjct: 304 MATKQVETLDPVLIRPGRIDKKIEFHLPDEKTKKHIFQIHTSRMTLANDVTLDDLIMAKD 363

Query: 389 DLSGADIKAICTEAGLMALRERRMKVTNEDFKKSKENVLYKKQEGTPEGLYL 440
           D SGADIKAICTEAGLMALRE RMK TNEDFKKS E+VLYKK EG PEGLYL
Sbjct: 364 DFSGADIKAICTEAGLMALREHRMKATNEDFKKSIESVLYKKHEGIPEGLYL 415


>gi|89064750 PREDICTED: similar to proteasome 26S ATPase subunit 4
           [Homo sapiens]
          Length = 414

 Score =  393 bits (1009), Expect = e-109
 Identities = 187/369 (50%), Positives = 282/369 (76%), Gaps = 2/369 (0%)

Query: 64  KLERIKDYLLMEEEFIRNQEQMKPLEEKQEEERSKVDDLRGTPMSVGTLEEIIDDNHAIV 123
           KL++  ++L ++EE+I++++  K L+++    + +V  ++  P+ +G   E +D N AIV
Sbjct: 42  KLQQELEFLEVQEEYIKDEQ--KNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIV 99

Query: 124 STSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTDPLVTVMKVEKAPQET 183
            ++ GS +YV ILS +D++LL+P  SV L+   +A++ VL  + D  + ++  ++ P   
Sbjct: 100 GSTTGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVM 159

Query: 184 YADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQT 243
           YADIGG+D Q QE++E+VELPLTH E Y+++GI PP+GV++YGPPG GKT+LAKAVA+ T
Sbjct: 160 YADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHT 219

Query: 244 SATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGER 303
           +A F+RVVGSE +QKYLG+GP++VR++FR+A+E+AP+I+FIDEIDAI TKR+D+ +G +R
Sbjct: 220 TAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADR 279

Query: 304 EIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKKR 363
           E+QR +LELLNQ+DGFD   +VKVIMATNR +TLDPAL+RPGR+DRKIEFPLPD + K+ 
Sbjct: 280 EVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRL 339

Query: 364 IFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFKKSK 423
           IF   TS+M L+++V L+D +   D +SGADI +IC E+G++A+RE R  V  +DF+K+ 
Sbjct: 340 IFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEKAY 399

Query: 424 ENVLYKKQE 432
           + V+ K ++
Sbjct: 400 KTVIKKDEQ 408


>gi|5729991 proteasome 26S ATPase subunit 4 isoform 1 [Homo sapiens]
          Length = 418

 Score =  393 bits (1009), Expect = e-109
 Identities = 187/369 (50%), Positives = 282/369 (76%), Gaps = 2/369 (0%)

Query: 64  KLERIKDYLLMEEEFIRNQEQMKPLEEKQEEERSKVDDLRGTPMSVGTLEEIIDDNHAIV 123
           KL++  ++L ++EE+I++++  K L+++    + +V  ++  P+ +G   E +D N AIV
Sbjct: 46  KLQQELEFLEVQEEYIKDEQ--KNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIV 103

Query: 124 STSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTDPLVTVMKVEKAPQET 183
            ++ GS +YV ILS +D++LL+P  SV L+   +A++ VL  + D  + ++  ++ P   
Sbjct: 104 GSTTGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVM 163

Query: 184 YADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQT 243
           YADIGG+D Q QE++E+VELPLTH E Y+++GI PP+GV++YGPPG GKT+LAKAVA+ T
Sbjct: 164 YADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHT 223

Query: 244 SATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGER 303
           +A F+RVVGSE +QKYLG+GP++VR++FR+A+E+AP+I+FIDEIDAI TKR+D+ +G +R
Sbjct: 224 TAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADR 283

Query: 304 EIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKKR 363
           E+QR +LELLNQ+DGFD   +VKVIMATNR +TLDPAL+RPGR+DRKIEFPLPD + K+ 
Sbjct: 284 EVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRL 343

Query: 364 IFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFKKSK 423
           IF   TS+M L+++V L+D +   D +SGADI +IC E+G++A+RE R  V  +DF+K+ 
Sbjct: 344 IFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEKAY 403

Query: 424 ENVLYKKQE 432
           + V+ K ++
Sbjct: 404 KTVIKKDEQ 412


>gi|24430155 proteasome 26S ATPase subunit 4 isoform 2 [Homo
           sapiens]
          Length = 387

 Score =  384 bits (986), Expect = e-107
 Identities = 181/345 (52%), Positives = 263/345 (76%)

Query: 88  LEEKQEEERSKVDDLRGTPMSVGTLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDLLEPG 147
           LE+     + +V  ++  P+ +G   E +D N AIV ++ GS +YV ILS +D++LL+P 
Sbjct: 37  LEDLYSRYKEEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPN 96

Query: 148 CSVLLNHKVHAVIGVLMDDTDPLVTVMKVEKAPQETYADIGGLDNQIQEIKESVELPLTH 207
            SV L+   +A++ VL  + D  + ++  ++ P   YADIGG+D Q QE++E+VELPLTH
Sbjct: 97  ASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTH 156

Query: 208 PEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLV 267
            E Y+++GI PP+GV++YGPPG GKT+LAKAVA+ T+A F+RVVGSE +QKYLG+GP++V
Sbjct: 157 FELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMV 216

Query: 268 RELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKV 327
           R++FR+A+E+AP+I+FIDEIDAI TKR+D+ +G +RE+QR +LELLNQ+DGFD   +VKV
Sbjct: 217 RDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKV 276

Query: 328 IMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAK 387
           IMATNR +TLDPAL+RPGR+DRKIEFPLPD + K+ IF   TS+M L+++V L+D +   
Sbjct: 277 IMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARP 336

Query: 388 DDLSGADIKAICTEAGLMALRERRMKVTNEDFKKSKENVLYKKQE 432
           D +SGADI +IC E+G++A+RE R  V  +DF+K+ + V+ K ++
Sbjct: 337 DKISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTVIKKDEQ 381


>gi|24497435 proteasome 26S ATPase subunit 5 [Homo sapiens]
          Length = 406

 Score =  346 bits (888), Expect = 2e-95
 Identities = 180/377 (47%), Positives = 250/377 (66%), Gaps = 4/377 (1%)

Query: 60  LKLLKLERIKDYLLMEEEFIRN----QEQMKPLEEKQEEERSKVDDLRGTPMSVGTLEEI 115
           L+   L +I++  L+  +  +N    Q Q   L  K    R ++  L+     VG +   
Sbjct: 20  LRQYYLSKIEELQLIVNDKSQNLRRLQAQRNELNAKVRLLREELQLLQEQGSYVGEVVRA 79

Query: 116 IDDNHAIVSTSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTDPLVTVMK 175
           +D    +V      +  V +   +D + + P C V L +  + +  +L +  DPLV++M 
Sbjct: 80  MDKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMM 139

Query: 176 VEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLL 235
           VEK P  TY  IGGLD QI+EIKE +ELP+ HPE +E +GI  PKGV+LYGPPGTGKTLL
Sbjct: 140 VEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLL 199

Query: 236 AKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRY 295
           A+AVA+ T  TF+RV GSEL+QK++G+G ++VRELF +A EHAPSI+F+DEID+IG+ R 
Sbjct: 200 ARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRL 259

Query: 296 DSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPL 355
           +  SGG+ E+QRTMLELLNQLDGF++  ++KVIMATNRI+ LD AL+RPGRIDRKIEFP 
Sbjct: 260 EGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPP 319

Query: 356 PDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVT 415
           P+E+ +  I +IH+ +M L   + L  +       SGA++K +CTEAG+ ALRERR+ VT
Sbjct: 320 PNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVT 379

Query: 416 NEDFKKSKENVLYKKQE 432
            EDF+ +   V+ K  E
Sbjct: 380 QEDFEMAVAKVMQKDSE 396


>gi|21361144 proteasome 26S ATPase subunit 3 [Homo sapiens]
          Length = 439

 Score =  346 bits (888), Expect = 2e-95
 Identities = 171/379 (45%), Positives = 253/379 (66%), Gaps = 20/379 (5%)

Query: 73  LMEEEFIRNQEQMKPLEEKQEEERSKVDDLRGTPMSVGTLEEIIDDNH------------ 120
           +M+ E +R   +++ +++K +E   K+   +  P  V  + E++D +             
Sbjct: 54  IMKSEVLRVTHELQAMKDKIKENSEKIKVNKTLPYLVSNVIELLDVDPNDQEEDGANIDL 113

Query: 121 --------AIVSTSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTDPLVT 172
                   A++ TS    +++ ++  VD + L+PG  V +N   + ++  L  + D  V 
Sbjct: 114 DSQRKGKCAVIKTSTRQTYFLPVIGLVDAEKLKPGDLVGVNKDSYLILETLPTEYDSRVK 173

Query: 173 VMKVEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGK 232
            M+V++ P E Y+DIGGLD QIQE+ E++ LP+ H E +E +GI+PPKGV++YGPPGTGK
Sbjct: 174 AMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNHKEKFENLGIQPPKGVLMYGPPGTGK 233

Query: 233 TLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGT 292
           TLLA+A A QT ATFL++ G +L+Q ++GDG KLVR+ F +A+E APSI+FIDE+DAIGT
Sbjct: 234 TLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPSIIFIDELDAIGT 293

Query: 293 KRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIE 352
           KR+DS   G+RE+QRTMLELLNQLDGF     VKVI ATNR++ LDPAL+R GR+DRKIE
Sbjct: 294 KRFDSEKAGDREVQRTMLELLNQLDGFQPNTQVKVIAATNRVDILDPALLRSGRLDRKIE 353

Query: 353 FPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRM 412
           FP+P+E+ + RI QIH+ +M ++ DV  ++L    DD +GA  KA+C EAG++ALR    
Sbjct: 354 FPMPNEEARARIMQIHSRKMNVSPDVNYEELARCTDDFNGAQCKAVCVEAGMIALRRGAT 413

Query: 413 KVTNEDFKKSKENVLYKKQ 431
           ++T+ED+ +    V  KK+
Sbjct: 414 ELTHEDYMEGILEVQAKKK 432


>gi|4506209 proteasome 26S ATPase subunit 2 [Homo sapiens]
          Length = 433

 Score =  314 bits (805), Expect = 9e-86
 Identities = 159/336 (47%), Positives = 228/336 (67%), Gaps = 6/336 (1%)

Query: 106 PMSVGTLEEII----DDNHAIVSTSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIG 161
           P+ V    +II    +D   I++    ++  V +   V    +E G  V ++   + +  
Sbjct: 92  PLQVARCTKIINADSEDPKYIINVKQFAKFVVDLSDQVAPTDIEEGMRVGVDRNKYQIHI 151

Query: 162 VLMDDTDPLVTVMKVEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKG 221
            L    DP VT+M+VE+ P  TY+D+GG   QI++++E VE PL HPE +  +GI+PPKG
Sbjct: 152 PLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKG 211

Query: 222 VILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSI 281
           V+L+GPPGTGKTL A+AVAN+T A F+RV+GSEL+QKY+G+G ++VRELF +A      +
Sbjct: 212 VLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACL 271

Query: 282 VFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPAL 341
           +F DEIDAIG  R+D  +GG+ E+QRTMLEL+NQLDGFD RG++KV+MATNR +TLDPAL
Sbjct: 272 IFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPAL 331

Query: 342 IRPGRIDRKIEFPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTE 401
           +RPGR+DRKIEF LPD + +  IF+IH   M++  D+  + L     + +GA+I+++CTE
Sbjct: 332 MRPGRLDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTE 391

Query: 402 AGLMALRERRMKVTNEDFKKSKENVL--YKKQEGTP 435
           AG+ A+R RR   T +DF ++   V+  Y K   TP
Sbjct: 392 AGMFAIRARRKIATEKDFLEAVNKVIKSYAKFSATP 427


>gi|195539395 proteasome 26S ATPase subunit 6 [Homo sapiens]
          Length = 403

 Score =  306 bits (784), Expect = 2e-83
 Identities = 152/350 (43%), Positives = 227/350 (64%)

Query: 82  QEQMKPLEEKQEEERSKVDDLRGTPMSVGTLEEIIDDNHAIVSTSVGSEHYVSILSFVDK 141
           +EQ+K L ++ E+  + +  L+     VG + + + +   IV  + G  + V     +DK
Sbjct: 44  REQLKELTKQYEKSENDLKALQSVGQIVGEVLKQLTEEKFIVKATNGPRYVVGCRRQLDK 103

Query: 142 DLLEPGCSVLLNHKVHAVIGVLMDDTDPLVTVMKVEKAPQETYADIGGLDNQIQEIKESV 201
             L+PG  V L+     ++  L  + DPLV  M  E     +Y++IGGL  QI+E++E +
Sbjct: 104 SKLKPGTRVALDMTTLTIMRYLPREVDPLVYNMSHEDPGNVSYSEIGGLSEQIRELREVI 163

Query: 202 ELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLG 261
           ELPLT+PE ++ +GI PPKG +LYGPPGTGKTLLA+AVA+Q    FL+VV S ++ KY+G
Sbjct: 164 ELPLTNPELFQRVGIIPPKGCLLYGPPGTGKTLLARAVASQLDCNFLKVVSSSIVDKYIG 223

Query: 262 DGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDS 321
           +  +L+RE+F  A +H P I+F+DEIDAIG +R+   +  +REIQRT++ELLNQ+DGFD+
Sbjct: 224 ESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDT 283

Query: 322 RGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKKRIFQIHTSRMTLADDVTLD 381
              VK+IMATNR +TLDPAL+RPGR+DRKI   LP+E+ +  I +IH   +T   ++  +
Sbjct: 284 LHRVKMIMATNRPDTLDPALLRPGRLDRKIHIDLPNEQARLDILKIHAGPITKHGEIDYE 343

Query: 382 DLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFKKSKENVLYKKQ 431
            ++   D  +GAD++ +CTEAG+ A+R     V  EDF K+   V   K+
Sbjct: 344 AIVKLSDGFNGADLRNVCTEAGMFAIRADHDFVVQEDFMKAVRKVADSKK 393


>gi|157671927 spermatogenesis associated 5 [Homo sapiens]
          Length = 893

 Score =  221 bits (563), Expect = 1e-57
 Identities = 111/246 (45%), Positives = 163/246 (66%), Gaps = 1/246 (0%)

Query: 164 MDDTDPLVTVMKVEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVI 223
           M+D  P          P  +++DIGGL++   +++++VE PL HPE +  MGI+PPKGV+
Sbjct: 606 MNDIRPSAMREIAIDVPNVSWSDIGGLESIKLKLEQAVEWPLKHPESFIRMGIQPPKGVL 665

Query: 224 LYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVF 283
           LYGPPG  KT++AKA+AN++   FL + G EL+ KY+G+  + VRE FR A   APSI+F
Sbjct: 666 LYGPPGCSKTMIAKALANESGLNFLAIKGPELMNKYVGESERAVRETFRKARAVAPSIIF 725

Query: 284 IDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIR 343
            DE+DA+  +R  S+ G      R + +LL ++DG +   DV ++ ATNR + +D AL+R
Sbjct: 726 FDELDALAVER-GSSLGAGNVADRVLAQLLTEMDGIEQLKDVTILAATNRPDRIDKALMR 784

Query: 344 PGRIDRKIEFPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAG 403
           PGRIDR I  PLPD  T++ IF++    M ++++V LD+LI+  D  SGA+I A+C EA 
Sbjct: 785 PGRIDRIIYVPLPDAATRREIFKLQFHSMPVSNEVDLDELILQTDAYSGAEIVAVCREAA 844

Query: 404 LMALRE 409
           L+AL E
Sbjct: 845 LLALEE 850



 Score =  176 bits (446), Expect = 4e-44
 Identities = 98/235 (41%), Positives = 142/235 (60%), Gaps = 1/235 (0%)

Query: 183 TYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQ 242
           TY  IGGL +Q++ I+E +ELPL  PE ++  GI  P+GV+LYGPPGTGKT++A+AVAN+
Sbjct: 351 TYDMIGGLSSQLKAIREIIELPLKQPELFKSYGIPAPRGVLLYGPPGTGKTMIARAVANE 410

Query: 243 TSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGE 302
             A    + G E+I K+ G+    +R++F  A    PSI+FIDE+DA+  KR  + +  E
Sbjct: 411 VGAYVSVINGPEIISKFYGETEAKLRQIFAEATLRHPSIIFIDELDALCPKREGAQNEVE 470

Query: 303 REIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKK 362
           + +  ++L L++ +    S G V V+ ATNR   LD AL RPGR D++IE  +P+ + + 
Sbjct: 471 KRVVASLLTLMDGIGSEVSEGQVLVLGATNRPHALDAALRRPGRFDKEIEIGVPNAQDRL 530

Query: 363 RIFQIHTSRMT-LADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVTN 416
            I Q    R+  L  +  L  L  +     GAD+K +C EAGL ALR    K  N
Sbjct: 531 DILQKLLRRVPHLLTEAELLQLANSAHGYVGADLKVLCNEAGLCALRRILKKQPN 585


>gi|6005942 valosin-containing protein [Homo sapiens]
          Length = 806

 Score =  215 bits (547), Expect = 7e-56
 Identities = 112/257 (43%), Positives = 163/257 (63%), Gaps = 3/257 (1%)

Query: 162 VLMDDTDPLVTVMKVEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKG 221
           V+  + +P+    + E   +  Y DIGG   Q+ +IKE VELPL HP  ++ +G+KPP+G
Sbjct: 181 VIHCEGEPIKREDEEESLNEVGYDDIGGCRKQLAQIKEMVELPLRHPALFKAIGVKPPRG 240

Query: 222 VILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSI 281
           ++LYGPPGTGKTL+A+AVAN+T A F  + G E++ K  G+    +R+ F  AE++AP+I
Sbjct: 241 ILLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAI 300

Query: 282 VFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPAL 341
           +FIDE+DAI  KR  ++   ER   R + +LL  +DG   R  V V+ ATNR  ++DPAL
Sbjct: 301 IFIDELDAIAPKREKTHGEVER---RIVSQLLTLMDGLKQRAHVIVMAATNRPNSIDPAL 357

Query: 342 IRPGRIDRKIEFPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTE 401
            R GR DR+++  +PD   +  I QIHT  M LADDV L+ +        GAD+ A+C+E
Sbjct: 358 RRFGRFDREVDIGIPDATGRLEILQIHTKNMKLADDVDLEQVANETHGHVGADLAALCSE 417

Query: 402 AGLMALRERRMKVTNED 418
           A L A+R++   +  ED
Sbjct: 418 AALQAIRKKMDLIDLED 434



 Score =  199 bits (507), Expect = 3e-51
 Identities = 110/307 (35%), Positives = 180/307 (58%), Gaps = 10/307 (3%)

Query: 112 LEEIIDDNHAIVSTSVGSEHYVSILSFVDK--DLLEPGCSVLLNHKVHAVIGVLMDD--- 166
           LE++ ++ H  V   + +    + L  + K  DL++     + + +V   + V MDD   
Sbjct: 396 LEQVANETHGHVGADLAALCSEAALQAIRKKMDLIDLEDETI-DAEVMNSLAVTMDDFRW 454

Query: 167 ----TDPLVTVMKVEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGV 222
               ++P      V + PQ T+ DIGGL++  +E++E V+ P+ HP+ + + G+ P KGV
Sbjct: 455 ALSQSNPSALRETVVEVPQVTWEDIGGLEDVKRELQELVQYPVEHPDKFLKFGMTPSKGV 514

Query: 223 ILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIV 282
           + YGPPG GKTLLAKA+AN+  A F+ + G EL+  + G+    VRE+F  A + AP ++
Sbjct: 515 LFYGPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVREIFDKARQAAPCVL 574

Query: 283 FIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALI 342
           F DE+D+I   R  +   G     R + ++L ++DG  ++ +V +I ATNR + +DPA++
Sbjct: 575 FFDELDSIAKARGGNIGDGGGAADRVINQILTEMDGMSTKKNVFIIGATNRPDIIDPAIL 634

Query: 343 RPGRIDRKIEFPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEA 402
           RPGR+D+ I  PLPDEK++  I + +  +  +A DV L+ L    +  SGAD+  IC  A
Sbjct: 635 RPGRLDQLIYIPLPDEKSRVAILKANLRKSPVAKDVDLEFLAKMTNGFSGADLTEICQRA 694

Query: 403 GLMALRE 409
             +A+RE
Sbjct: 695 CKLAIRE 701


>gi|5802970 AFG3 ATPase family gene 3-like 2 [Homo sapiens]
          Length = 797

 Score =  197 bits (500), Expect = 2e-50
 Identities = 105/248 (42%), Positives = 153/248 (61%), Gaps = 5/248 (2%)

Query: 184 YADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQT 243
           + D+ G +    EI E V   L +P+ Y+++G K PKG IL GPPGTGKTLLAKA A + 
Sbjct: 307 FKDVAGCEEAKLEIMEFVNF-LKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAKATAGEA 365

Query: 244 SATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGER 303
           +  F+ V GSE ++ ++G GP  VR+LF +A ++AP I+FIDEIDA+G KR   N GG+ 
Sbjct: 366 NVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRKRGRGNFGGQS 425

Query: 304 EIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKKR 363
           E + T+ +LL ++DGF++  +V ++  TNR + LDPAL+RPGR DR+I    PD K +  
Sbjct: 426 EQENTLNQLLVEMDGFNTTTNVVILAGTNRPDILDPALLRPGRFDRQIFIGPPDIKGRAS 485

Query: 364 IFQIHTSRM----TLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDF 419
           IF++H   +    TL  D     L       SGAD+  +C EA L+A R     +  + F
Sbjct: 486 IFKVHLRPLKLDSTLEKDKLARKLASLTPGFSGADVANVCNEAALIAARHLSDSINQKHF 545

Query: 420 KKSKENVL 427
           +++ E V+
Sbjct: 546 EQAIERVI 553


>gi|153792536 ATPase family, AAA domain containing 2B [Homo sapiens]
          Length = 1458

 Score =  191 bits (484), Expect = 1e-48
 Identities = 111/258 (43%), Positives = 156/258 (60%), Gaps = 17/258 (6%)

Query: 160 IGVLMDDTDPLVTVMKVEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPP 219
           +G  + D DP    M ++K+ +  +  IGGL + I  +KE V  PL +PE +E+  I+PP
Sbjct: 381 VGASLADVDP----MNIDKSVR--FDSIGGLSHHIHALKEMVVFPLLYPEIFEKFKIQPP 434

Query: 220 KGVILYGPPGTGKTLLAKAVANQTS------ATFLRVVGSELIQKYLGDGPKLVRELFRV 273
           +G + YGPPGTGKTL+A+A+AN+ S      A F+R  G++ + K++G+  + +R LF  
Sbjct: 435 RGCLFYGPPGTGKTLVARALANECSQGDKKVAFFMRK-GADCLSKWVGESERQLRLLFDQ 493

Query: 274 AEEHAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNR 333
           A    PSI+F DEID +   R          I  T+L L+   DG D+RG++ VI ATNR
Sbjct: 494 AYLMRPSIIFFDEIDGLAPVRSSRQDQIHSSIVSTLLALM---DGLDNRGEIVVIGATNR 550

Query: 334 IETLDPALIRPGRIDRKIEFPLPDEKTKKRIFQIHTSRMT-LADDVTLDDLIMAKDDLSG 392
           ++++DPAL RPGR DR+  F LPD+K +K I QIHT        D  L +L        G
Sbjct: 551 LDSIDPALRRPGRFDREFLFNLPDQKARKHILQIHTRDWNPKLSDAFLGELAEKCVGYCG 610

Query: 393 ADIKAICTEAGLMALRER 410
           ADIKA+CTEA L+ALR R
Sbjct: 611 ADIKALCTEAALIALRRR 628


>gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]
          Length = 1390

 Score =  188 bits (477), Expect = 1e-47
 Identities = 109/263 (41%), Positives = 152/263 (57%), Gaps = 15/263 (5%)

Query: 154 HKVHAVIGVLMDDTDPLVTVMKVEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEE 213
           +K    IG  + D DP+     V       +  +GGL N I  +KE V  PL +PE +E+
Sbjct: 401 YKDRMKIGASLADVDPMQLDSSVR------FDSVGGLSNHIAALKEMVVFPLLYPEVFEK 454

Query: 214 MGIKPPKGVILYGPPGTGKTLLAKAVANQTSATFLRVV-----GSELIQKYLGDGPKLVR 268
             I+PP+G + YGPPGTGKTL+A+A+AN+ S    RV      G++ + K++G+  + +R
Sbjct: 455 FKIQPPRGCLFYGPPGTGKTLVARALANECSQGDKRVAFFMRKGADCLSKWVGESERQLR 514

Query: 269 ELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVI 328
            LF  A +  PSI+F DEID +   R          I  T+L L   +DG DSRG++ VI
Sbjct: 515 LLFDQAYQMRPSIIFFDEIDGLAPVRSSRQDQIHSSIVSTLLAL---MDGLDSRGEIVVI 571

Query: 329 MATNRIETLDPALIRPGRIDRKIEFPLPDEKTKKRIFQIHTSRMTLAD-DVTLDDLIMAK 387
            ATNR++++DPAL RPGR DR+  F LPD++ +K I +IHT        D  L++L    
Sbjct: 572 GATNRLDSIDPALRRPGRFDREFLFSLPDKEARKEILKIHTRDWNPKPLDTFLEELAENC 631

Query: 388 DDLSGADIKAICTEAGLMALRER 410
               GADIK+IC EA L ALR R
Sbjct: 632 VGYCGADIKSICAEAALCALRRR 654


>gi|229577436 spermatogenesis associated 5-like 1 [Homo sapiens]
          Length = 753

 Score =  177 bits (448), Expect = 2e-44
 Identities = 102/265 (38%), Positives = 155/265 (58%), Gaps = 23/265 (8%)

Query: 184 YADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQT 243
           + +IGGL++   ++K+S+E PL  P  +  MG+  PKGV+LYGPPG  KT L +A+A   
Sbjct: 463 WEEIGGLEDVKLKLKQSIEWPLKFPWEFVRMGLTQPKGVLLYGPPGCAKTTLVRALATSC 522

Query: 244 SATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGER 303
             +F+ V G++L   ++GD  K++ ++FR A    P+I+F+DEID+I   R  S +G + 
Sbjct: 523 HCSFVSVSGADLFSPFVGDSEKVLSQIFRQARASTPAILFLDEIDSILGARSASKTGCDV 582

Query: 304 EIQRTMLELLNQLDG-----FDSRG--------------DVKVIMATNRIETLDPALIRP 344
           + +R +  LLN+LDG      + RG               V +I ATNR + LD AL+RP
Sbjct: 583 Q-ERVLSVLLNELDGVGLKTIERRGSKSSQQEFQEVFNRSVMIIAATNRPDVLDTALLRP 641

Query: 345 GRIDRKIEFPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGL 404
           GR+D+ I  P PD K +  I ++ T  M +  DV+L++L       SGAD++ +CTEA L
Sbjct: 642 GRLDKIIYIPPPDHKGRLSILKVCTKTMPIGPDVSLENLAAETCFFSGADLRNLCTEAAL 701

Query: 405 MALRERRMKVT---NEDFKKSKENV 426
           +AL+E  +  T    E F KS + V
Sbjct: 702 LALQENGLDATTVKQEHFLKSLKTV 726



 Score =  144 bits (364), Expect = 1e-34
 Identities = 91/257 (35%), Positives = 134/257 (52%), Gaps = 13/257 (5%)

Query: 178 KAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAK 237
           +A  +    +GGL      ++E + LPL +P     +G+  P+GV+L GPPG GKT L +
Sbjct: 193 EAQPQPEVPLGGLSEAADSLRELLRLPLRYPRALTALGLAVPRGVLLAGPPGVGKTQLVR 252

Query: 238 AVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHA---PSIVFIDEIDAIGTKR 294
           AVA +  A  L V    L     G+  + VR +F+ A E A   PS++F+DE+DA+  +R
Sbjct: 253 AVAREAGAELLAVSAPALQGSRPGETEENVRRVFQRARELASRGPSLLFLDEMDALCPQR 312

Query: 295 YDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFP 354
                G      R + ++L  LDG     +V V+ ATNR + LDPAL RPGR DR++   
Sbjct: 313 -----GSRAPESRVVAQVLTLLDGASGDREVVVVGATNRPDALDPALRRPGRFDREVVIG 367

Query: 355 LPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKV 414
            P  K +K I Q+ TS+M ++  V L  L        GAD+ A+C EA + AL       
Sbjct: 368 TPTLKQRKEILQVITSKMPISSHVDLGLLAEMTVGYVGADLTALCREAAMHALLHSEKNQ 427

Query: 415 TNE-----DFKKSKENV 426
            N      DF ++ +N+
Sbjct: 428 DNPVIDEIDFLEAFKNI 444


>gi|4507173 spastic paraplegia 7 isoform 1 [Homo sapiens]
          Length = 795

 Score =  172 bits (435), Expect = 7e-43
 Identities = 101/248 (40%), Positives = 143/248 (57%), Gaps = 4/248 (1%)

Query: 183 TYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQ 242
           ++ D+ G+     E++E V+  L  PE + ++G K PKG +L GPPG GKTLLAKAVA +
Sbjct: 307 SFKDVAGMHEAKLEVREFVDY-LKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVATE 365

Query: 243 TSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSG-G 301
               FL + G E ++   G G   VR LF+ A   AP IV+IDEIDA+G KR  + SG  
Sbjct: 366 AQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTTMSGFS 425

Query: 302 EREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTK 361
             E ++T+ +LL ++DG  +   V V+ +TNR + LD AL+RPGR+DR +   LP  + +
Sbjct: 426 NTEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADILDGALMRPGRLDRHVFIDLPTLQER 485

Query: 362 KRIFQIHTSRMTLADDVTLDDLIMAK--DDLSGADIKAICTEAGLMALRERRMKVTNEDF 419
           + IF+ H   + L    T     +A+     SGADI  IC EA L A RE    V   +F
Sbjct: 486 REIFEQHLKSLKLTQSSTFYSQRLAELTPGFSGADIANICNEAALHAAREGHTSVHTLNF 545

Query: 420 KKSKENVL 427
           + + E VL
Sbjct: 546 EYAVERVL 553


>gi|45643125 nuclear VCP-like isoform 2 [Homo sapiens]
          Length = 750

 Score =  170 bits (430), Expect = 3e-42
 Identities = 93/245 (37%), Positives = 150/245 (61%), Gaps = 10/245 (4%)

Query: 180 PQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAV 239
           P  T+ADIG L++  +E+  ++  P+ +P+ ++ +G+  P GV+L GPPG GKTLLAKAV
Sbjct: 470 PNVTWADIGALEDIREELTMAILAPVRNPDQFKALGLVTPAGVLLAGPPGCGKTLLAKAV 529

Query: 240 ANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNS 299
           AN++   F+ V G EL+  Y+G+  + VR++F+ A+  AP ++F DE+DA+  +R D  +
Sbjct: 530 ANESGLNFISVKGPELLNMYVGESERAVRQVFQRAKNSAPCVIFFDEVDALCPRRSDRET 589

Query: 300 GGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEK 359
           G      R + +LL ++DG ++R  V ++ ATNR + +DPA++RPGR+D+ +   LP   
Sbjct: 590 GAS---VRVVNQLLTEMDGLEARQQVFIMAATNRPDIIDPAILRPGRLDKTLFVGLPPPA 646

Query: 360 TKKRIFQIHTSRMT---LADDVTLDDLI--MAKDDLSGADIKAICTEAGLMALRER--RM 412
            +  I +  T   T   L  DV L+ +   +  D  +GAD+ A+  EA + ALR+   R 
Sbjct: 647 DRLAILKTITKNGTKPPLDADVNLEAIAGDLRCDCYTGADLSALVREASICALRQEMARQ 706

Query: 413 KVTNE 417
           K  NE
Sbjct: 707 KSGNE 711



 Score =  167 bits (422), Expect = 2e-41
 Identities = 94/241 (39%), Positives = 140/241 (58%), Gaps = 2/241 (0%)

Query: 184 YADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQT 243
           + D+GG D  ++E+ + + + + HPE Y  +G+ PP+GV+L+GPPG GKTLLA A+A + 
Sbjct: 158 FEDVGGNDMTLKEVCKML-IHMRHPEVYHHLGVVPPRGVLLHGPPGCGKTLLAHAIAGEL 216

Query: 244 SATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGER 303
               L+V   E++    G+  + +RELF  A  +AP I+FIDEIDAI  KR  ++   ER
Sbjct: 217 DLPILKVAAPEIVSGVSGESEQKLRELFEQAVSNAPCIIFIDEIDAITPKREVASKDMER 276

Query: 304 EIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKKR 363
            I   +L  ++ L+   +   V VI ATNR ++LDPAL R GR DR+I   +PDE +++R
Sbjct: 277 RIVAQLLTCMDDLNNVAATARVLVIGATNRPDSLDPALRRAGRFDREICLGIPDEASRER 336

Query: 364 IFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFKKSK 423
           I Q    ++ L        L        GAD+ A+C EA + A+    MK+  E  KK+ 
Sbjct: 337 ILQTLCRKLRLPQAFDFCHLAHLTPGFVGADLMALCREAAMCAVNRVLMKL-QEQQKKNP 395

Query: 424 E 424
           E
Sbjct: 396 E 396


>gi|45643123 nuclear VCP-like isoform 1 [Homo sapiens]
          Length = 856

 Score =  170 bits (430), Expect = 3e-42
 Identities = 93/245 (37%), Positives = 150/245 (61%), Gaps = 10/245 (4%)

Query: 180 PQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAV 239
           P  T+ADIG L++  +E+  ++  P+ +P+ ++ +G+  P GV+L GPPG GKTLLAKAV
Sbjct: 576 PNVTWADIGALEDIREELTMAILAPVRNPDQFKALGLVTPAGVLLAGPPGCGKTLLAKAV 635

Query: 240 ANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNS 299
           AN++   F+ V G EL+  Y+G+  + VR++F+ A+  AP ++F DE+DA+  +R D  +
Sbjct: 636 ANESGLNFISVKGPELLNMYVGESERAVRQVFQRAKNSAPCVIFFDEVDALCPRRSDRET 695

Query: 300 GGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEK 359
           G      R + +LL ++DG ++R  V ++ ATNR + +DPA++RPGR+D+ +   LP   
Sbjct: 696 GAS---VRVVNQLLTEMDGLEARQQVFIMAATNRPDIIDPAILRPGRLDKTLFVGLPPPA 752

Query: 360 TKKRIFQIHTSRMT---LADDVTLDDLI--MAKDDLSGADIKAICTEAGLMALRER--RM 412
            +  I +  T   T   L  DV L+ +   +  D  +GAD+ A+  EA + ALR+   R 
Sbjct: 753 DRLAILKTITKNGTKPPLDADVNLEAIAGDLRCDCYTGADLSALVREASICALRQEMARQ 812

Query: 413 KVTNE 417
           K  NE
Sbjct: 813 KSGNE 817



 Score =  167 bits (422), Expect = 2e-41
 Identities = 94/241 (39%), Positives = 140/241 (58%), Gaps = 2/241 (0%)

Query: 184 YADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQT 243
           + D+GG D  ++E+ + + + + HPE Y  +G+ PP+GV+L+GPPG GKTLLA A+A + 
Sbjct: 264 FEDVGGNDMTLKEVCKML-IHMRHPEVYHHLGVVPPRGVLLHGPPGCGKTLLAHAIAGEL 322

Query: 244 SATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGER 303
               L+V   E++    G+  + +RELF  A  +AP I+FIDEIDAI  KR  ++   ER
Sbjct: 323 DLPILKVAAPEIVSGVSGESEQKLRELFEQAVSNAPCIIFIDEIDAITPKREVASKDMER 382

Query: 304 EIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKKR 363
            I   +L  ++ L+   +   V VI ATNR ++LDPAL R GR DR+I   +PDE +++R
Sbjct: 383 RIVAQLLTCMDDLNNVAATARVLVIGATNRPDSLDPALRRAGRFDREICLGIPDEASRER 442

Query: 364 IFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFKKSK 423
           I Q    ++ L        L        GAD+ A+C EA + A+    MK+  E  KK+ 
Sbjct: 443 ILQTLCRKLRLPQAFDFCHLAHLTPGFVGADLMALCREAAMCAVNRVLMKL-QEQQKKNP 501

Query: 424 E 424
           E
Sbjct: 502 E 502


>gi|4505725 peroxin1 [Homo sapiens]
          Length = 1283

 Score =  169 bits (427), Expect = 6e-42
 Identities = 90/241 (37%), Positives = 141/241 (58%), Gaps = 3/241 (1%)

Query: 187  IGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSAT 246
            IGGL    Q + ++++LP  +PE +  + I+   G++LYGPPGTGKTLLA  +A ++   
Sbjct: 842  IGGLHEVRQILMDTIQLPAKYPELFANLPIRQRTGILLYGPPGTGKTLLAGVIARESRMN 901

Query: 247  FLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGEREIQ 306
            F+ V G EL+ KY+G   + VR++F  A+   P I+F DE ++I  +R   N+G      
Sbjct: 902  FISVKGPELLSKYIGASEQAVRDIFIRAQAAKPCILFFDEFESIAPRRGHDNTG---VTD 958

Query: 307  RTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKKRIFQ 366
            R + +LL QLDG +    V V+ AT+R + +DPAL+RPGR+D+ +  P PD+ ++  I  
Sbjct: 959  RVVNQLLTQLDGVEGLQGVYVLAATSRPDLIDPALLRPGRLDKCVYCPPPDQVSRLEILN 1018

Query: 367  IHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFKKSKENV 426
            + +  + LADDV L  +    D  +GAD+KA+   A L AL    +    +D   S ++ 
Sbjct: 1019 VLSDSLPLADDVDLQHVASVTDSFTGADLKALLYNAQLEALHGMLLSSGLQDGSSSSDSD 1078

Query: 427  L 427
            L
Sbjct: 1079 L 1079



 Score = 37.4 bits (85), Expect = 0.027
 Identities = 36/129 (27%), Positives = 60/129 (46%), Gaps = 8/129 (6%)

Query: 222 VILYGPPGTGKTLLAKAVANQT----SATFLRVVGSELIQKYLGDGPKLVRELFRVAEEH 277
           ++L G  G+GK+ LAKA+  +      A   RV    L  K L +  K +   F  A   
Sbjct: 595 LLLTGGKGSGKSTLAKAICKEAFDKLDAHVERVDCKALRGKRLENIQKTLEVAFSEAVWM 654

Query: 278 APSIVFIDEIDAIG---TKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRI 334
            PS+V +D++D I          +S    + QR    L + +  F S G +  ++AT++ 
Sbjct: 655 QPSVVLLDDLDLIAGLPAVPEHEHSPDAVQSQRLAHALNDMIKEFISMGSLVALIATSQS 714

Query: 335 -ETLDPALI 342
            ++L P L+
Sbjct: 715 QQSLHPLLV 723


>gi|194018488 peroxisomal biogenesis factor 6 [Homo sapiens]
          Length = 980

 Score =  167 bits (424), Expect = 1e-41
 Identities = 98/235 (41%), Positives = 144/235 (61%), Gaps = 5/235 (2%)

Query: 178 KAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAK 237
           K P  ++ D+GGL    +EI E+++LPL HPE    +G++   G++L+GPPGTGKTLLAK
Sbjct: 698 KIPSVSWHDVGGLQEVKKEILETIQLPLEHPELLS-LGLRR-SGLLLHGPPGTGKTLLAK 755

Query: 238 AVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDS 297
           AVA + S TFL V G ELI  Y+G   + VRE+F  A   AP I+F DE+D++   R  S
Sbjct: 756 AVATECSLTFLSVKGPELINMYVGQSEENVREVFARARAAAPCIIFFDELDSLAPSRGRS 815

Query: 298 NSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPD 357
              G   + R + +LL +LDG  S  DV VI ATNR + LDPAL+RPGR D+ +     +
Sbjct: 816 GDSG-GVMDRVVSQLLAELDGLHSTQDVFVIGATNRPDLLDPALLRPGRFDKLVFVGANE 874

Query: 358 EKTKK-RIFQIHTSRMTLADDVTLDDLI-MAKDDLSGADIKAICTEAGLMALRER 410
           ++  + R+    T +  L   V+L +++      L+GAD+ ++C++A   AL+ R
Sbjct: 875 DRASQLRVLSAITRKFKLEPSVSLVNVLDCCPPQLTGADLYSLCSDAMTAALKRR 929



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 45/185 (24%), Positives = 79/185 (42%), Gaps = 4/185 (2%)

Query: 222 VILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSI 281
           V+L GPPG GKT +  A  +      L+V  S L  +  G     ++ +F  A    P++
Sbjct: 466 VLLRGPPGCGKTTVVAAACSHLGLHLLKVPCSSLCAESSGAVETKLQAIFSRARRCRPAV 525

Query: 282 VFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPAL 341
           + +  +D +G  R     G +  +   +  LL   D  +S   + V+  T+R + L PA 
Sbjct: 526 LLLTAVDLLGRDR--DGLGEDARVMAVLRHLLLNEDPLNSCPPLMVVATTSRAQDL-PAD 582

Query: 342 IRPGRIDRKIEFPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTE 401
           ++      ++E P   E  +  I +  T+ + L  +V L  L          D+ A+ T 
Sbjct: 583 VQTA-FPHELEVPALSEGQRLSILRALTAHLPLGQEVNLAQLARRCAGFVVGDLYALLTH 641

Query: 402 AGLMA 406
           +   A
Sbjct: 642 SSRAA 646


>gi|5901990 katanin p60 subunit A 1 [Homo sapiens]
          Length = 491

 Score =  161 bits (408), Expect = 1e-39
 Identities = 103/260 (39%), Positives = 149/260 (57%), Gaps = 15/260 (5%)

Query: 176 VEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPP-KGVILYGPPGTGKTL 234
           + + P   + DI  L    + +KE+V LP+  PE+++  GI+ P KGV++ GPPGTGKTL
Sbjct: 200 ISQNPNVRWDDIADLVEAKKLLKEAVVLPMWMPEFFK--GIRRPWKGVLMVGPPGTGKTL 257

Query: 235 LAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKR 294
           LAKAVA +   TF  V  S L  KY G+  KLVR LF +A  ++P+ +FIDEID+I ++R
Sbjct: 258 LAKAVATECKTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYSPATIFIDEIDSICSRR 317

Query: 295 YDSNSGGEREIQRTMLELLNQLDGFDSRGD-------VKVIMATNRIETLDPALIRPGRI 347
               S      +R   ELL Q+DG     +       V V+ ATN    +D AL R  R+
Sbjct: 318 --GTSEEHEASRRVKAELLVQMDGVGGTSENDDPSKMVMVLAATNFPWDIDEALRR--RL 373

Query: 348 DRKIEFPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMAL 407
           +++I  PLP  K ++ + +I    + LADDV L  +    +  SGADI  +C +A LMA+
Sbjct: 374 EKRIYIPLPSAKGREELLRISLRELELADDVDLASIAENMEGYSGADITNVCRDASLMAM 433

Query: 408 RERRMKVTNEDFKK-SKENV 426
           R R   +T E+ +  SKE +
Sbjct: 434 RRRIEGLTPEEIRNLSKEEM 453


>gi|21327685 YME1-like 1 isoform 1 [Homo sapiens]
          Length = 773

 Score =  160 bits (406), Expect = 2e-39
 Identities = 90/245 (36%), Positives = 145/245 (59%), Gaps = 3/245 (1%)

Query: 183 TYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQ 242
           T+  + G++   QE++E VE  L +P+ +  +G K PKG++L GPPGTGKTLLA+AVA +
Sbjct: 337 TFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGILLVGPPGTGKTLLARAVAGE 395

Query: 243 TSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGE 302
               F    GSE  + ++G G   +R LFR A+ +AP ++FIDE+D++G KR +S     
Sbjct: 396 ADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIESPM--H 453

Query: 303 REIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKK 362
              ++T+ +LL ++DGF     V +I ATN  E LD ALIRPGR D ++  P PD K + 
Sbjct: 454 PYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGRT 513

Query: 363 RIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFKKS 422
            I + + +++     V  + +       SGA+++ +  +A L A  + +  VT ++ + S
Sbjct: 514 EILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKAAVDGKEMVTMKELEFS 573

Query: 423 KENVL 427
           K+ +L
Sbjct: 574 KDKIL 578


>gi|7657689 YME1-like 1 isoform 3 [Homo sapiens]
          Length = 716

 Score =  160 bits (406), Expect = 2e-39
 Identities = 90/245 (36%), Positives = 145/245 (59%), Gaps = 3/245 (1%)

Query: 183 TYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQ 242
           T+  + G++   QE++E VE  L +P+ +  +G K PKG++L GPPGTGKTLLA+AVA +
Sbjct: 280 TFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGILLVGPPGTGKTLLARAVAGE 338

Query: 243 TSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGE 302
               F    GSE  + ++G G   +R LFR A+ +AP ++FIDE+D++G KR +S     
Sbjct: 339 ADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIESPM--H 396

Query: 303 REIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKK 362
              ++T+ +LL ++DGF     V +I ATN  E LD ALIRPGR D ++  P PD K + 
Sbjct: 397 PYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGRT 456

Query: 363 RIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFKKS 422
            I + + +++     V  + +       SGA+++ +  +A L A  + +  VT ++ + S
Sbjct: 457 EILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKAAVDGKEMVTMKELEFS 516

Query: 423 KENVL 427
           K+ +L
Sbjct: 517 KDKIL 521


>gi|62177112 katanin p60 subunit A-like 1 [Homo sapiens]
          Length = 490

 Score =  156 bits (395), Expect = 3e-38
 Identities = 100/260 (38%), Positives = 150/260 (57%), Gaps = 15/260 (5%)

Query: 176 VEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPP-KGVILYGPPGTGKTL 234
           V + P   + DI  L+   + ++E+V LP+  P++++  GI+ P KGV++ GPPGTGKT+
Sbjct: 199 VSRNPSIHWDDIADLEEAKKLLREAVVLPMWMPDFFK--GIRRPWKGVLMVGPPGTGKTM 256

Query: 235 LAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKR 294
           LAKAVA +   TF  V  S L  KY G+  KLVR LF +A  +AP+ +FIDEID+I ++R
Sbjct: 257 LAKAVATECGTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYAPTTIFIDEIDSICSRR 316

Query: 295 YDSNSGGEREIQRTMLELLNQLDGF-------DSRGDVKVIMATNRIETLDPALIRPGRI 347
               S      +R   ELL Q+DG        D    V V+ ATN    +D AL R  R+
Sbjct: 317 --GTSDEHEASRRVKSELLIQMDGVGGALENDDPSKMVMVLAATNFPWDIDEALRR--RL 372

Query: 348 DRKIEFPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMAL 407
           +++I  PLP  K +  + +I+   + L  D+ L+D+    +  SGADI  +C +A LMA+
Sbjct: 373 EKRIYIPLPTAKGRAELLKINLREVELDPDIQLEDIAEKIEGYSGADITNVCRDASLMAM 432

Query: 408 RERRMKVTNEDFKK-SKENV 426
           R R   ++ E+ +  SKE +
Sbjct: 433 RRRINGLSPEEIRALSKEEL 452


>gi|14149767 katanin p60 subunit A-like 1 [Homo sapiens]
          Length = 490

 Score =  156 bits (395), Expect = 3e-38
 Identities = 100/260 (38%), Positives = 150/260 (57%), Gaps = 15/260 (5%)

Query: 176 VEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPP-KGVILYGPPGTGKTL 234
           V + P   + DI  L+   + ++E+V LP+  P++++  GI+ P KGV++ GPPGTGKT+
Sbjct: 199 VSRNPSIHWDDIADLEEAKKLLREAVVLPMWMPDFFK--GIRRPWKGVLMVGPPGTGKTM 256

Query: 235 LAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKR 294
           LAKAVA +   TF  V  S L  KY G+  KLVR LF +A  +AP+ +FIDEID+I ++R
Sbjct: 257 LAKAVATECGTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYAPTTIFIDEIDSICSRR 316

Query: 295 YDSNSGGEREIQRTMLELLNQLDGF-------DSRGDVKVIMATNRIETLDPALIRPGRI 347
               S      +R   ELL Q+DG        D    V V+ ATN    +D AL R  R+
Sbjct: 317 --GTSDEHEASRRVKSELLIQMDGVGGALENDDPSKMVMVLAATNFPWDIDEALRR--RL 372

Query: 348 DRKIEFPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMAL 407
           +++I  PLP  K +  + +I+   + L  D+ L+D+    +  SGADI  +C +A LMA+
Sbjct: 373 EKRIYIPLPTAKGRAELLKINLREVELDPDIQLEDIAEKIEGYSGADITNVCRDASLMAM 432

Query: 408 RERRMKVTNEDFKK-SKENV 426
           R R   ++ E+ +  SKE +
Sbjct: 433 RRRINGLSPEEIRALSKEEL 452


>gi|31742536 fidgetin-like 1 [Homo sapiens]
          Length = 674

 Score =  148 bits (373), Expect = 1e-35
 Identities = 85/237 (35%), Positives = 136/237 (57%), Gaps = 11/237 (4%)

Query: 176 VEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIK-PPKGVILYGPPGTGKTL 234
           ++  P   + DI G++     IKE V  P+  P+ +   G++ PPKG++L+GPPGTGKTL
Sbjct: 392 MDHGPPVNWEDIAGVEFAKATIKEIVVWPMLRPDIFT--GLRGPPKGILLFGPPGTGKTL 449

Query: 235 LAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKR 294
           + K +A+Q+ ATF  +  S L  K++G+G K+VR LF VA    P+++FIDEID++ ++R
Sbjct: 450 IGKCIASQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEIDSLLSQR 509

Query: 295 YDSNSGGEREIQRTMLELLNQLDG--FDSRGDVKVIMATNRIETLDPALIRPGRIDRKIE 352
            D      R I+    E L QLDG    S   + V+ ATNR + +D A  R  R+ +++ 
Sbjct: 510 GDGEHESSRRIK---TEFLVQLDGATTSSEDRILVVGATNRPQEIDEAARR--RLVKRLY 564

Query: 353 FPLPDEKTKKRI-FQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALR 408
            PLP+   +K+I   + +       +  ++ ++   D  SGAD+  +C EA L  +R
Sbjct: 565 IPLPEASARKQIVINLMSKEQCCLSEEEIEQIVQQSDAFSGADMTQLCREASLGPIR 621


>gi|112789543 fidgetin-like 1 [Homo sapiens]
          Length = 674

 Score =  148 bits (373), Expect = 1e-35
 Identities = 85/237 (35%), Positives = 136/237 (57%), Gaps = 11/237 (4%)

Query: 176 VEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIK-PPKGVILYGPPGTGKTL 234
           ++  P   + DI G++     IKE V  P+  P+ +   G++ PPKG++L+GPPGTGKTL
Sbjct: 392 MDHGPPVNWEDIAGVEFAKATIKEIVVWPMLRPDIFT--GLRGPPKGILLFGPPGTGKTL 449

Query: 235 LAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKR 294
           + K +A+Q+ ATF  +  S L  K++G+G K+VR LF VA    P+++FIDEID++ ++R
Sbjct: 450 IGKCIASQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEIDSLLSQR 509

Query: 295 YDSNSGGEREIQRTMLELLNQLDG--FDSRGDVKVIMATNRIETLDPALIRPGRIDRKIE 352
            D      R I+    E L QLDG    S   + V+ ATNR + +D A  R  R+ +++ 
Sbjct: 510 GDGEHESSRRIK---TEFLVQLDGATTSSEDRILVVGATNRPQEIDEAARR--RLVKRLY 564

Query: 353 FPLPDEKTKKRI-FQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALR 408
            PLP+   +K+I   + +       +  ++ ++   D  SGAD+  +C EA L  +R
Sbjct: 565 IPLPEASARKQIVINLMSKEQCCLSEEEIEQIVQQSDAFSGADMTQLCREASLGPIR 621


>gi|156564401 vesicle-fusing ATPase [Homo sapiens]
          Length = 744

 Score =  145 bits (366), Expect = 7e-35
 Identities = 95/269 (35%), Positives = 148/269 (55%), Gaps = 32/269 (11%)

Query: 187 IGGLDNQIQEI-KESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSA 245
           IGGLD +  +I + +    +  PE  E+MG K  KG++LYGPPG GKTLLA+ +    +A
Sbjct: 220 IGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNA 279

Query: 246 TFLRVV-GSELIQKYLGDGPKLVRELFRVAEEHAPS--------IVFIDEIDAIGTKRYD 296
              +VV G E++ KY+G+    +R+LF  AEE            I+  DEIDAI  +R  
Sbjct: 280 REPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQR-- 337

Query: 297 SNSGGEREIQRTML-ELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPL 355
            +  G   +  T++ +LL+++DG +   ++ VI  TNR + +D AL+RPGR++ K+E  L
Sbjct: 338 GSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGL 397

Query: 356 PDEKTKKRIFQIHTSRM----TLADDVTLDDLIMAKDDLSGADIKAICTEAGLMAL---- 407
           PDEK + +I  IHT+RM     L+ DV + +L +   + SGA+++ +   A   A+    
Sbjct: 398 PDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHI 457

Query: 408 -----------RERRMKVTNEDFKKSKEN 425
                      +   ++VT  DF  S EN
Sbjct: 458 KASTKVEVDMEKAESLQVTRGDFLASLEN 486



 Score = 35.0 bits (79), Expect = 0.14
 Identities = 21/77 (27%), Positives = 42/77 (54%), Gaps = 7/77 (9%)

Query: 218 PPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGP----KLVRELFRV 273
           P   V+L GPP +GKT LA  +A +++  F+++   +   K +G       + ++++F  
Sbjct: 535 PLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPD---KMIGFSETAKCQAMKKIFDD 591

Query: 274 AEEHAPSIVFIDEIDAI 290
           A +   S V +D+I+ +
Sbjct: 592 AYKSQLSCVVVDDIERL 608


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.135    0.379 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,822,464
Number of Sequences: 37866
Number of extensions: 835590
Number of successful extensions: 3934
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 82
Number of HSP's successfully gapped in prelim test: 66
Number of HSP's that attempted gapping in prelim test: 3696
Number of HSP's gapped (non-prelim): 256
length of query: 440
length of database: 18,247,518
effective HSP length: 105
effective length of query: 335
effective length of database: 14,271,588
effective search space: 4780981980
effective search space used: 4780981980
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.