Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 116805348
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|116805348 trinucleotide repeat containing 6A [Homo sapiens]
(1962 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|116805348 trinucleotide repeat containing 6A [Homo sapiens] 4049 0.0
gi|217416332 trinucleotide repeat containing 6C isoform 1 [Homo ... 1207 0.0
gi|33413425 trinucleotide repeat containing 6C isoform 2 [Homo s... 1169 0.0
gi|241982729 trinucleotide repeat containing 6B isoform 1 [Homo ... 1100 0.0
gi|148491080 trinucleotide repeat containing 6B isoform 2 [Homo ... 868 0.0
gi|67782330 trinucleotide repeat containing 6B isoform 3 [Homo s... 606 e-173
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 113 2e-24
gi|57864582 hornerin [Homo sapiens] 92 7e-18
gi|60097902 filaggrin [Homo sapiens] 78 7e-14
gi|169173184 PREDICTED: hypothetical protein [Homo sapiens] 73 2e-12
gi|239754269 PREDICTED: hypothetical protein [Homo sapiens] 73 2e-12
gi|169168665 PREDICTED: hypothetical protein [Homo sapiens] 73 2e-12
gi|113417486 PREDICTED: hypothetical protein [Homo sapiens] 73 2e-12
gi|239740898 PREDICTED: hypothetical protein [Homo sapiens] 73 2e-12
gi|239740777 PREDICTED: hypothetical protein [Homo sapiens] 73 2e-12
gi|239740724 PREDICTED: hypothetical protein [Homo sapiens] 73 2e-12
gi|239740674 PREDICTED: hypothetical protein [Homo sapiens] 73 2e-12
gi|239740645 PREDICTED: hypothetical protein [Homo sapiens] 73 2e-12
gi|239513940 PREDICTED: hypothetical protein [Homo sapiens] 73 2e-12
gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo ... 72 4e-12
gi|33286444 mastermind-like 2 [Homo sapiens] 72 7e-12
gi|62122917 filaggrin family member 2 [Homo sapiens] 71 1e-11
gi|33356174 pinin, desmosome associated protein [Homo sapiens] 69 5e-11
gi|33946327 nucleoporin 214kDa [Homo sapiens] 68 8e-11
gi|161016767 mucin 21 [Homo sapiens] 66 3e-10
gi|239757861 PREDICTED: similar to armadillo repeat containing, ... 62 4e-09
gi|110347429 mediator complex subunit 12 [Homo sapiens] 61 9e-09
gi|32307128 nuclear receptor coactivator 6 [Homo sapiens] 59 6e-08
gi|17017963 forkhead box P2 isoform I [Homo sapiens] 58 8e-08
gi|22538413 forkhead box P2 isoform III [Homo sapiens] 58 8e-08
>gi|116805348 trinucleotide repeat containing 6A [Homo sapiens]
Length = 1962
Score = 4049 bits (10502), Expect = 0.0
Identities = 1962/1962 (100%), Positives = 1962/1962 (100%)
Query: 1 MRELEAKATKDVERNLSRDLVQEEEQLMEEKKKKKDDKKKKEAAQKKATEQKIKVPEQIK 60
MRELEAKATKDVERNLSRDLVQEEEQLMEEKKKKKDDKKKKEAAQKKATEQKIKVPEQIK
Sbjct: 1 MRELEAKATKDVERNLSRDLVQEEEQLMEEKKKKKDDKKKKEAAQKKATEQKIKVPEQIK 60
Query: 61 PSVSQPQPANSNNGTSTATSTNNNAKRATANNQQPQQQQQQQQPQQQQPQQQPQPQPQQQ 120
PSVSQPQPANSNNGTSTATSTNNNAKRATANNQQPQQQQQQQQPQQQQPQQQPQPQPQQQ
Sbjct: 61 PSVSQPQPANSNNGTSTATSTNNNAKRATANNQQPQQQQQQQQPQQQQPQQQPQPQPQQQ 120
Query: 121 QPQQQPQALPRYPREVPPRFRHQEHKQLLKRGQHFPVIAANLGSAVKVLNSQSESSALTN 180
QPQQQPQALPRYPREVPPRFRHQEHKQLLKRGQHFPVIAANLGSAVKVLNSQSESSALTN
Sbjct: 121 QPQQQPQALPRYPREVPPRFRHQEHKQLLKRGQHFPVIAANLGSAVKVLNSQSESSALTN 180
Query: 181 QQPQNNGEVQNSKNQSDINHSTSGSHYENSQRGPVSSTSDSSTNCKNAVVSDLSEKEAWP 240
QQPQNNGEVQNSKNQSDINHSTSGSHYENSQRGPVSSTSDSSTNCKNAVVSDLSEKEAWP
Sbjct: 181 QQPQNNGEVQNSKNQSDINHSTSGSHYENSQRGPVSSTSDSSTNCKNAVVSDLSEKEAWP 240
Query: 241 SAPGSDPELASECMDADSASSSESERNITIMASGNTGGEKDGLRNSTGLGSQNKFVVGSS 300
SAPGSDPELASECMDADSASSSESERNITIMASGNTGGEKDGLRNSTGLGSQNKFVVGSS
Sbjct: 241 SAPGSDPELASECMDADSASSSESERNITIMASGNTGGEKDGLRNSTGLGSQNKFVVGSS 300
Query: 301 SNNVGHGSSTGPWGFSHGAIISTCQVSVDAPESKSESSNNRMNAWGTVSSSSNGGLNPST 360
SNNVGHGSSTGPWGFSHGAIISTCQVSVDAPESKSESSNNRMNAWGTVSSSSNGGLNPST
Sbjct: 301 SNNVGHGSSTGPWGFSHGAIISTCQVSVDAPESKSESSNNRMNAWGTVSSSSNGGLNPST 360
Query: 361 LNSASNHGAWPVLENNGLALKGPVGSGSSGINIQCSTIGQMPNNQSINSKVSGGSTHGTW 420
LNSASNHGAWPVLENNGLALKGPVGSGSSGINIQCSTIGQMPNNQSINSKVSGGSTHGTW
Sbjct: 361 LNSASNHGAWPVLENNGLALKGPVGSGSSGINIQCSTIGQMPNNQSINSKVSGGSTHGTW 420
Query: 421 GSLQETCESEVSGTQKVSFSGQPQNITTEMTGPNNTTNFMTSSLPNSGSVQNNELPSSNT 480
GSLQETCESEVSGTQKVSFSGQPQNITTEMTGPNNTTNFMTSSLPNSGSVQNNELPSSNT
Sbjct: 421 GSLQETCESEVSGTQKVSFSGQPQNITTEMTGPNNTTNFMTSSLPNSGSVQNNELPSSNT 480
Query: 481 GAWRVSTMNHPQMQAPSGMNGTSLSHLSNGESKSGGSYGTTWGAYGSNYSGDKCSGPNGQ 540
GAWRVSTMNHPQMQAPSGMNGTSLSHLSNGESKSGGSYGTTWGAYGSNYSGDKCSGPNGQ
Sbjct: 481 GAWRVSTMNHPQMQAPSGMNGTSLSHLSNGESKSGGSYGTTWGAYGSNYSGDKCSGPNGQ 540
Query: 541 ANGDTVNATLMQPGVNGPMGTNFQVNTNKGGGVWESGAANSQSTSWGSGNGANSGGSRRG 600
ANGDTVNATLMQPGVNGPMGTNFQVNTNKGGGVWESGAANSQSTSWGSGNGANSGGSRRG
Sbjct: 541 ANGDTVNATLMQPGVNGPMGTNFQVNTNKGGGVWESGAANSQSTSWGSGNGANSGGSRRG 600
Query: 601 WGTPAQNTGTNLPSVEWNKLPSNQHSNDSANGNGKTFTNGWKSTEEEDQGSATSQTNEQS 660
WGTPAQNTGTNLPSVEWNKLPSNQHSNDSANGNGKTFTNGWKSTEEEDQGSATSQTNEQS
Sbjct: 601 WGTPAQNTGTNLPSVEWNKLPSNQHSNDSANGNGKTFTNGWKSTEEEDQGSATSQTNEQS 660
Query: 661 SVWAKTGGTVESDGSTESTGRLEEKGTGESQSRDRRKIDQHTLLQSIVNRTDLDPRVLSN 720
SVWAKTGGTVESDGSTESTGRLEEKGTGESQSRDRRKIDQHTLLQSIVNRTDLDPRVLSN
Sbjct: 661 SVWAKTGGTVESDGSTESTGRLEEKGTGESQSRDRRKIDQHTLLQSIVNRTDLDPRVLSN 720
Query: 721 SGWGQTPIKQNTAWDTETSPRGERKTDNGTEAWGSSATQTFNSGACIDKTSPNGNDTSSV 780
SGWGQTPIKQNTAWDTETSPRGERKTDNGTEAWGSSATQTFNSGACIDKTSPNGNDTSSV
Sbjct: 721 SGWGQTPIKQNTAWDTETSPRGERKTDNGTEAWGSSATQTFNSGACIDKTSPNGNDTSSV 780
Query: 781 SGWGDPKPALRWGDSKGSNCQGGWEDDSAATGMVKSNQWGNCKEEKAAWNDSQKNKQGWG 840
SGWGDPKPALRWGDSKGSNCQGGWEDDSAATGMVKSNQWGNCKEEKAAWNDSQKNKQGWG
Sbjct: 781 SGWGDPKPALRWGDSKGSNCQGGWEDDSAATGMVKSNQWGNCKEEKAAWNDSQKNKQGWG 840
Query: 841 DGQKSSQGWSVSASDNWGETSRNNHWGEANKKSSSGGSDSDRSVSGWNELGKTSSFTWGN 900
DGQKSSQGWSVSASDNWGETSRNNHWGEANKKSSSGGSDSDRSVSGWNELGKTSSFTWGN
Sbjct: 841 DGQKSSQGWSVSASDNWGETSRNNHWGEANKKSSSGGSDSDRSVSGWNELGKTSSFTWGN 900
Query: 901 NINPNNSSGWDESSKPTPSQGWGDPPKSNQSLGWGDSSKPVSSPDWNKQQDIVGSWGIPP 960
NINPNNSSGWDESSKPTPSQGWGDPPKSNQSLGWGDSSKPVSSPDWNKQQDIVGSWGIPP
Sbjct: 901 NINPNNSSGWDESSKPTPSQGWGDPPKSNQSLGWGDSSKPVSSPDWNKQQDIVGSWGIPP 960
Query: 961 ATGKPPGTGWLGGPIPAPAKEEEPTGWEEPSPESIRRKMEIDDGTSAWGDPSKYNYKNVN 1020
ATGKPPGTGWLGGPIPAPAKEEEPTGWEEPSPESIRRKMEIDDGTSAWGDPSKYNYKNVN
Sbjct: 961 ATGKPPGTGWLGGPIPAPAKEEEPTGWEEPSPESIRRKMEIDDGTSAWGDPSKYNYKNVN 1020
Query: 1021 MWNKNVPNGNSRSDQQAQVHQLLTPASAISNKEASSGSGWGEPWGEPSTPATTVDNGTSA 1080
MWNKNVPNGNSRSDQQAQVHQLLTPASAISNKEASSGSGWGEPWGEPSTPATTVDNGTSA
Sbjct: 1021 MWNKNVPNGNSRSDQQAQVHQLLTPASAISNKEASSGSGWGEPWGEPSTPATTVDNGTSA 1080
Query: 1081 WGKPIDSGPSWGEPIAAASSTSTWGSSSVGPQALSKSGPKSMQDGWCGDDMPLPGNRPTG 1140
WGKPIDSGPSWGEPIAAASSTSTWGSSSVGPQALSKSGPKSMQDGWCGDDMPLPGNRPTG
Sbjct: 1081 WGKPIDSGPSWGEPIAAASSTSTWGSSSVGPQALSKSGPKSMQDGWCGDDMPLPGNRPTG 1140
Query: 1141 WEEEEDVEIGMWNSNSSQELNSSLNWPPYTKKMSSKGLSGKKRRRERGMMKGGNKQEEAW 1200
WEEEEDVEIGMWNSNSSQELNSSLNWPPYTKKMSSKGLSGKKRRRERGMMKGGNKQEEAW
Sbjct: 1141 WEEEEDVEIGMWNSNSSQELNSSLNWPPYTKKMSSKGLSGKKRRRERGMMKGGNKQEEAW 1200
Query: 1201 INPFVKQFSNISFSRDSPEENVQSNKMDLSGGMLQDKRMEIDKHSLNIGDYNRTVGKGPG 1260
INPFVKQFSNISFSRDSPEENVQSNKMDLSGGMLQDKRMEIDKHSLNIGDYNRTVGKGPG
Sbjct: 1201 INPFVKQFSNISFSRDSPEENVQSNKMDLSGGMLQDKRMEIDKHSLNIGDYNRTVGKGPG 1260
Query: 1261 SRPQISKESSMERNPYFDKDGIVADESQNMQFMSSQSMKLPPSNSALPNQALGSIAGLGM 1320
SRPQISKESSMERNPYFDKDGIVADESQNMQFMSSQSMKLPPSNSALPNQALGSIAGLGM
Sbjct: 1261 SRPQISKESSMERNPYFDKDGIVADESQNMQFMSSQSMKLPPSNSALPNQALGSIAGLGM 1320
Query: 1321 QNLNSVRQNGNPSMFGVGNTAAQPRGMQQPPAQPLSSSQPNLRAQVPPPLLSPQVPVSLL 1380
QNLNSVRQNGNPSMFGVGNTAAQPRGMQQPPAQPLSSSQPNLRAQVPPPLLSPQVPVSLL
Sbjct: 1321 QNLNSVRQNGNPSMFGVGNTAAQPRGMQQPPAQPLSSSQPNLRAQVPPPLLSPQVPVSLL 1380
Query: 1381 KYAPNNGGLNPLFGPQQVAMLNQLSQLNQLSQISQLQRLLAQQQRAQSQRSVPSGNRPQQ 1440
KYAPNNGGLNPLFGPQQVAMLNQLSQLNQLSQISQLQRLLAQQQRAQSQRSVPSGNRPQQ
Sbjct: 1381 KYAPNNGGLNPLFGPQQVAMLNQLSQLNQLSQISQLQRLLAQQQRAQSQRSVPSGNRPQQ 1440
Query: 1441 DQQGRPLSVQQQMMQQSRQLDPNLLVKQQTPPSQQQPLHQPAMKSFLDNVMPHTTPELQK 1500
DQQGRPLSVQQQMMQQSRQLDPNLLVKQQTPPSQQQPLHQPAMKSFLDNVMPHTTPELQK
Sbjct: 1441 DQQGRPLSVQQQMMQQSRQLDPNLLVKQQTPPSQQQPLHQPAMKSFLDNVMPHTTPELQK 1500
Query: 1501 GPSPINAFSNFPIGLNSNLNVNMDMNSIKEPQSRLRKWTTVDSISVNTSLDQNSSKHGAI 1560
GPSPINAFSNFPIGLNSNLNVNMDMNSIKEPQSRLRKWTTVDSISVNTSLDQNSSKHGAI
Sbjct: 1501 GPSPINAFSNFPIGLNSNLNVNMDMNSIKEPQSRLRKWTTVDSISVNTSLDQNSSKHGAI 1560
Query: 1561 SSGFRLEESPFVPYDFMNSSTSPASPPGSIGDGWPRAKSPNGSSSVNWPPEFRPGEPWKG 1620
SSGFRLEESPFVPYDFMNSSTSPASPPGSIGDGWPRAKSPNGSSSVNWPPEFRPGEPWKG
Sbjct: 1561 SSGFRLEESPFVPYDFMNSSTSPASPPGSIGDGWPRAKSPNGSSSVNWPPEFRPGEPWKG 1620
Query: 1621 YPNIDPETDPYVTPGSVINNLSINTVREVDHLRDRNSGSSSSLNTTLPSTSAWSSIRASN 1680
YPNIDPETDPYVTPGSVINNLSINTVREVDHLRDRNSGSSSSLNTTLPSTSAWSSIRASN
Sbjct: 1621 YPNIDPETDPYVTPGSVINNLSINTVREVDHLRDRNSGSSSSLNTTLPSTSAWSSIRASN 1680
Query: 1681 YNVPLSSTAQSTSARNSDSKLTWSPGSVTNTSLAHELWKVPLPPKNITAPSRPPPGLTGQ 1740
YNVPLSSTAQSTSARNSDSKLTWSPGSVTNTSLAHELWKVPLPPKNITAPSRPPPGLTGQ
Sbjct: 1681 YNVPLSSTAQSTSARNSDSKLTWSPGSVTNTSLAHELWKVPLPPKNITAPSRPPPGLTGQ 1740
Query: 1741 KPPLSTWDNSPLRIGGGWGNSDARYTPGSSWGESSSGRITNWLVLKNLTPQIDGSTLRTL 1800
KPPLSTWDNSPLRIGGGWGNSDARYTPGSSWGESSSGRITNWLVLKNLTPQIDGSTLRTL
Sbjct: 1741 KPPLSTWDNSPLRIGGGWGNSDARYTPGSSWGESSSGRITNWLVLKNLTPQIDGSTLRTL 1800
Query: 1801 CMQHGPLITFHLNLPHGNALVRYSSKEEVVKAQKSLHMCVLGNTTILAEFASEEEISRFF 1860
CMQHGPLITFHLNLPHGNALVRYSSKEEVVKAQKSLHMCVLGNTTILAEFASEEEISRFF
Sbjct: 1801 CMQHGPLITFHLNLPHGNALVRYSSKEEVVKAQKSLHMCVLGNTTILAEFASEEEISRFF 1860
Query: 1861 AQSQSLTPSPGWQSLGSSQSRLGSLDCSHSFSSRTDLNHWNGAGLSGTNCGDLHGTSLWG 1920
AQSQSLTPSPGWQSLGSSQSRLGSLDCSHSFSSRTDLNHWNGAGLSGTNCGDLHGTSLWG
Sbjct: 1861 AQSQSLTPSPGWQSLGSSQSRLGSLDCSHSFSSRTDLNHWNGAGLSGTNCGDLHGTSLWG 1920
Query: 1921 TPHYSTSLWGPPSSSDPRGISSPSPINAFLSVDHLGGGGESM 1962
TPHYSTSLWGPPSSSDPRGISSPSPINAFLSVDHLGGGGESM
Sbjct: 1921 TPHYSTSLWGPPSSSDPRGISSPSPINAFLSVDHLGGGGESM 1962
>gi|217416332 trinucleotide repeat containing 6C isoform 1 [Homo
sapiens]
Length = 1726
Score = 1207 bits (3124), Expect = 0.0
Identities = 794/1816 (43%), Positives = 1012/1816 (55%), Gaps = 222/1816 (12%)
Query: 271 MASGNTGGEKDG-LRNSTGLGSQNKFVVGSSSNNVG--------HGSSTGPWGFSHGAII 321
MA+G+ G G + + G N +V S SN +GS+ WG + G+
Sbjct: 1 MATGSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSS 60
Query: 322 STCQVSVDAPESKSES---SNNRMNAWGTVSSSSNGGLNPSTLNSASNHGAWPVLENNGL 378
SV + K ++ N WG +S+SN G+N + LN +N AWPVL + G
Sbjct: 61 GLAHCSVSGGDGKMDTMIGDGRSQNCWG--ASNSNAGINLN-LNPNANPAAWPVLGHEGT 117
Query: 379 ALKGPVGSGSSGINIQCSTIGQMPNNQSINSKVSGGSTHGTWGSL--QETCESEVSGTQK 436
G S S + S IGQ NQ+ N T G WG+L QE+ E + S +Q
Sbjct: 118 VATGNPSSICSPV----SAIGQNMGNQNGNPT----GTLGAWGNLLPQESTEPQTSTSQN 169
Query: 437 VSFSGQPQNITTEMTGPNNTTNFMTSSLPNSGSVQNNELPSSNTGAWRVSTMNHPQMQAP 496
VSFS QPQN+ T+ GPNNT N M SS ++Q N LP+ A + + P +Q
Sbjct: 170 VSFSAQPQNLNTD--GPNNT-NPMNSSPNPINAMQTNGLPNWGM-AVGMGAIIPPHLQGL 225
Query: 497 SGMNGTSLSHLSNGESKSGGSYGTTWGAYGSNYSGDKCSGPNGQANGDTVNATLMQPGVN 556
G NG+S+S +S G ++ G + WG N + + Q NGDTVN+ L N
Sbjct: 226 PGANGSSVSQVSGGSAE--GISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQ-N 282
Query: 557 GPMGTNFQVNTNKGGGVWESGA-ANSQSTSWGSGNGANSGGSRRG--WGTPAQNTGTNLP 613
G ++ GG W+SG A +WG G+G N G+ WG P+++T +
Sbjct: 283 G--SSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVN 340
Query: 614 SVEWNKLPSNQHSNDSANGNGKTFTNGWKSTEEEDQGSATSQTNEQSSVWAK--TGGTVE 671
EW K P NQHSN NG G T GW+S Q E + WAK + GT
Sbjct: 341 G-EWGK-PPNQHSNSDINGKGST---GWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTA 395
Query: 672 SDGSTESTGRLEE-----KGTGESQSRDRRKIDQHTLLQSIVNRTDLDPRVLSNSGWGQT 726
S+GS++ +G E +GTGE + RD+ IDQ + + R DLDPRVLSN+GWGQT
Sbjct: 396 SEGSSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQ---LPRNDLDPRVLSNTGWGQT 452
Query: 727 PIKQNTAWDTETSPRGERKTDNGTEAWGSSATQTFNSGACIDKTSPNGNDTSSVSGWGDP 786
P+KQNTAW+ E SPR ERK DNGTEAWG +ATQ NSG D + N +TSSVSGW +
Sbjct: 453 PVKQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNA 512
Query: 787 KPAL-----RWGDS--KGSNCQGGWEDD------SAATGMVKSNQWG---NCKEEKAAWN 830
PA WGDS K + G W D S A + W N +++ W
Sbjct: 513 PPAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWG 572
Query: 831 DSQKNK-QGWGDGQKSSQGWSVSASDNWGETSRNNHWGEANKKSSSGGSDSDRSVSGWNE 889
+ K K Q WGDGQ+S+ WS D +S H G+ K S +DS+RS SGWN+
Sbjct: 573 EPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGWND 632
Query: 890 LGKTSSFTWGNNINP--NNSSGWDESSKPTPSQGWGDPPKSNQSLGWGDSSKPVSSPDWN 947
++ + WGN+ N N + W E+ KP P Q W P+ N WG +
Sbjct: 633 TTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGA---------- 682
Query: 948 KQQDIVGSWGIPPATGKPPGTGWLGGPIPAPAKEE-EPTGWEEPSPESIRRKMEIDDGTS 1006
A+ K GTGW+GGP+P K+ E TGWEEPSP SIRRKMEIDDGTS
Sbjct: 683 -------------ASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDGTS 729
Query: 1007 AWGDPSKYNYKNVNMWNKNVPNGNSRSDQQAQV----------HQLLTP----ASAISNK 1052
AWGDPS YN K VNMW++N P S + H++ TP A N+
Sbjct: 730 AWGDPSNYNNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNR 789
Query: 1053 EASSG---SGWGE----------PWGEPSTPATTVDNGTSAWGKPIDSGPSWGEPIAAAS 1099
G SGWGE WGEPS+P+T VDNGT+AWGKP SG WG+ A
Sbjct: 790 SPLLGPVSSGWGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAEPP 849
Query: 1100 STSTWGSSSVGPQALSKSGPKSMQDGWC--GDDMPLPGNRPTGWEEEEDVEIGMWNSNSS 1157
+ V AL K KSMQ+GW GD+M L ++ WE+EE +WN+ +S
Sbjct: 850 VAFGRAGAPVAASALCKPASKSMQEGWGSGGDEMNLSTSQ---WEDEEG---DVWNNAAS 903
Query: 1158 QELNSSLN-WPPYTKKMSSKGLSGKKRRRERGMMKGGNKQEEAWI-NPFVKQFSNISFSR 1215
QE SS + W KK KG MK KQ+EAWI + +KQ +++ F R
Sbjct: 904 QESTSSCSSWGNAPKKGLQKG------------MKTSGKQDEAWIMSRLIKQLTDMGFPR 951
Query: 1216 DSPEENVQSNKMDLSGGM--LQDKRMEIDKHSLNIGDYNRTVGKGPGSRPQISKESSMER 1273
+ EE ++SN M+L M L +K++++DK L + D+N K G RP ISKESS++R
Sbjct: 952 EPAEEALKSNNMNLDQAMSALLEKKVDVDKRGLGVTDHNGMAAKPLGCRPPISKESSVDR 1011
Query: 1274 NPYFDKDGIVADESQNMQFMSSQSMKLPPSNSALPNQALGSIA-GLGMQNLNSVRQ--NG 1330
+ DKDG + +E F+ S S+KLP S+SALP+QALG IA GLGMQNLNS RQ +G
Sbjct: 1012 PTFLDKDGGLVEEPTPSPFLPSPSLKLPLSHSALPSQALGGIASGLGMQNLNSSRQIPSG 1071
Query: 1331 NPSMFGVGNTAAQPRGMQQPP---AQPLSSSQPNLRAQVPPPLLSPQVPVSLLKYAPNNG 1387
N MFG + AAQ R MQQPP QPL+SSQP+LRAQVP LSPQV LL++A N
Sbjct: 1072 NLGMFG-NSGAAQARTMQQPPQPPVQPLNSSQPSLRAQVPQ-FLSPQVQAQLLQFAAKNI 1129
Query: 1388 GLNPLF-----GPQQVAMLNQLSQLNQLSQISQLQRLLAQQQRAQSQRSVPSGNRPQQDQ 1442
GLNP PQ + MLNQL QL QL+ QRL QQQ Q+QR+V R Q+ Q
Sbjct: 1130 GLNPALLTSPINPQHMTMLNQLYQL-QLAY----QRLQIQQQMLQAQRNVSGSMRQQEQQ 1184
Query: 1443 QGRPLS-VQQQMMQQSRQLDPNLLVKQQTPPSQQQ--PLHQPAMKSFLDNVMPHTT---- 1495
R ++ +QQQ+ Q RQL LLVKQ PP LH A KS +D+ H
Sbjct: 1185 VARTITNLQQQIQQHQRQLAQALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHPQTPGL 1244
Query: 1496 PELQ--KGPSPINAFSNFPI-GLNSNLNVN-MDMN---SIKEP---QSRLRKWTTVDSI- 1544
P+LQ + S N F+ +P+ GLN N+NVN MDM S+K+P QSRL +WT +S+
Sbjct: 1245 PDLQTKEQQSSPNTFAPYPLAGLNPNMNVNSMDMTGGLSVKDPSQSQSRLPQWTHPNSMD 1304
Query: 1545 ---SVNTSLDQNSSKHGAISSGFRLE-------ESPFVPYDFMNSSTSPASPPGSIGDGW 1594
S + L+QN SKHGAI G + + + YD + +S SPASPP ++ W
Sbjct: 1305 NLPSAASPLEQNPSKHGAIPGGLSIGPPGKSSIDDSYGRYDLIQNSESPASPPVAVPHSW 1364
Query: 1595 PRAKSPN----GSSSVNWPPEFRPGEPWKGYPNIDPETDPYVTPGSVINNLSINT-VREV 1649
RAKS + SS+NWPPEF PG PWKG NIDPE DP VTPGSV +INT +++V
Sbjct: 1365 SRAKSDSDKISNGSSINWPPEFHPGVPWKGLQNIDPENDPDVTPGSVPTGPTINTTIQDV 1424
Query: 1650 DHLRDRNSGSS--SSLNTTLPSTSAWSSIRASNYNVPLSS--TAQSTSARNSDSKLTWSP 1705
+ ++ GSS SS N TLPS+SAW + AS Y+ SS +A S + + SD K TWS
Sbjct: 1425 NRYLLKSGGSSPPSSQNATLPSSSAWP-LSASGYSSSFSSIASAPSVAGKLSDIKSTWSS 1483
Query: 1706 GSVTNT--SLAHELWKVPLPPKNITAPSRPPPGLTGQKPPLSTWDNSPLRIGGGWGNSDA 1763
G ++T SL+HELWKVP +N TAP+RPPPGLT KP STW SPL GW +S
Sbjct: 1484 GPTSHTQASLSHELWKVP---RNSTAPTRPPPGLTNPKPS-STWGASPL----GWTSS-- 1533
Query: 1764 RYTPGSSWGESSSGRITNWLVLKNLTPQIDGSTLRTLCMQHGPLITFHLNLPHGNALVRY 1823
Y+ GS+W +SGR ++WLVL+NLTPQIDGSTLRTLC+QHGPLITFHLNL GNA+VRY
Sbjct: 1534 -YSSGSAWSTDTSGRTSSWLVLRNLTPQIDGSTLRTLCLQHGPLITFHLNLTQGNAVVRY 1592
Query: 1824 SSKEEVVKAQKSLHMCVLGNTTILAEFASEEEISRFFAQSQSLTPSPGWQ-SLGSSQSRL 1882
SSKEE KAQKSLHMCVLGNTTILAEFA EEE++RF AQ Q+L P+ WQ S SSQ RL
Sbjct: 1593 SSKEEAAKAQKSLHMCVLGNTTILAEFAGEEEVNRFLAQGQALPPTSSWQSSSASSQPRL 1652
Query: 1883 GSLDCSHSFSSRTDLNHWNGAGLSGTNCGDLHGTSLW-GTPHYSTSLWGPPSSSDPRGIS 1941
+ SH R+D HWN L G +L LW G P YS+SLWGPPS+ D R I
Sbjct: 1653 SAAGSSHGL-VRSDAGHWNAPCLGGKGSSEL----LWGGVPQYSSSLWGPPSADDSRVIG 1707
Query: 1942 SPSPINAFLSVDHLGG 1957
SP+P+ L D L G
Sbjct: 1708 SPTPLTTLLPGDLLSG 1723
>gi|33413425 trinucleotide repeat containing 6C isoform 2 [Homo
sapiens]
Length = 1690
Score = 1169 bits (3025), Expect = 0.0
Identities = 775/1813 (42%), Positives = 987/1813 (54%), Gaps = 252/1813 (13%)
Query: 271 MASGNTGGEKDG-LRNSTGLGSQNKFVVGSSSNNVG--------HGSSTGPWGFSHGAII 321
MA+G+ G G + + G N +V S SN +GS+ WG + G+
Sbjct: 1 MATGSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSS 60
Query: 322 STCQVSVDAPESKSES---SNNRMNAWGTVSSSSNGGLNPSTLNSASNHGAWPVLENNGL 378
SV + K ++ N WG +S+SN G+N + LN +N AWPVL + G
Sbjct: 61 GLAHCSVSGGDGKMDTMIGDGRSQNCWG--ASNSNAGINLN-LNPNANPAAWPVLGHEGT 117
Query: 379 ALKGPVGSGSSGINIQCSTIGQMPNNQSINSKVSGGSTHGTWGSL--QETCESEVSGTQK 436
G S S + S IGQ NQ+ N T G WG+L QE+ E + S +Q
Sbjct: 118 VATGNPSSICSPV----SAIGQNMGNQNGNPT----GTLGAWGNLLPQESTEPQTSTSQN 169
Query: 437 VSFSGQPQNITTEMTGPNNTTNFMTSSLPNSGSVQNNELPSSNTGAWRVSTMNHPQMQAP 496
VSFS QPQN+ T+ GPNNT N M SS ++Q N LP+ A + + P +Q
Sbjct: 170 VSFSAQPQNLNTD--GPNNT-NPMNSSPNPINAMQTNGLPNWGM-AVGMGAIIPPHLQGL 225
Query: 497 SGMNGTSLSHLSNGESKSGGSYGTTWGAYGSNYSGDKCSGPNGQANGDTVNATLMQPGVN 556
G NG+S+S +S G ++ G + WG N + + Q NGDTVN+ L N
Sbjct: 226 PGANGSSVSQVSGGSAE--GISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQ-N 282
Query: 557 GPMGTNFQVNTNKGGGVWESGA-ANSQSTSWGSGNGANSGGSRRG--WGTPAQNTGTNLP 613
G ++ GG W+SG A +WG G+G N G+ WG P+++T +
Sbjct: 283 G--SSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVN 340
Query: 614 SVEWNKLPSNQHSNDSANGNGKTFTNGWKSTEEEDQGSATSQTNEQSSVWAK--TGGTVE 671
EW K P NQHSN NG G T GW+S Q E + WAK + GT
Sbjct: 341 G-EWGK-PPNQHSNSDINGKGST---GWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTA 395
Query: 672 SDGSTESTGRLEE-----KGTGESQSRDRRKIDQHTLLQSIVNRTDLDPRVLSNSGWGQT 726
S+GS++ +G E +GTGE + RD+ IDQ + + R DLDPRVLSN+GWGQT
Sbjct: 396 SEGSSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQ---LPRNDLDPRVLSNTGWGQT 452
Query: 727 PIKQNTAWDTETSPRGERKTDNGTEAWGSSATQTFNSGACIDKTSPNGNDTSSVSGWGDP 786
P+KQNTAW+ E SPR ERK DNGTEAWG +ATQ NSG D + N +TSSVSGW +
Sbjct: 453 PVKQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNA 512
Query: 787 KPAL-----RWGDS--KGSNCQGGWEDD------SAATGMVKSNQWG---NCKEEKAAWN 830
PA WGDS K + G W D S A + W N +++ W
Sbjct: 513 PPAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWG 572
Query: 831 DSQKNK-QGWGDGQKSSQGWSVSASDNWGETSRNNHWGEANKKSSSGGSDSDRSVSGWNE 889
+ K K Q WGDGQ+S+ WS D +S H G+ K S +DS+RS SGWN+
Sbjct: 573 EPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGWND 632
Query: 890 LGKTSSFTWGNNINP--NNSSGWDESSKPTPSQGWGDPPKSNQSLGWGDSSKPVSSPDWN 947
++ + WGN+ N N + W E+ KP P Q W P+ N WG +
Sbjct: 633 TTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGA---------- 682
Query: 948 KQQDIVGSWGIPPATGKPPGTGWLGGPIPAPAKEE-EPTGWEEPSPESIRRKMEIDDGTS 1006
A+ K GTGW+GGP+P K+ E TGWEEPSP SIRRKMEIDDGTS
Sbjct: 683 -------------ASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDGTS 729
Query: 1007 AWGDPSKYNYKNVNMWNKNVPNGNSRSDQQAQV----------HQLLTP----ASAISNK 1052
AWGDPS YN K VNMW++N P S + H++ TP A N+
Sbjct: 730 AWGDPSNYNNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNR 789
Query: 1053 EASSG------SGWGE----------PWGEPSTPATTVDNGTSAWGKPIDSGPSWGEPIA 1096
G SGWGE WGEPS+P+T VDNGT+AWGKP SG WG+ A
Sbjct: 790 SPLLGPGRKVSSGWGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPA 849
Query: 1097 AASSTSTWGSSSVGPQALSKSGPKSMQDGWC--GDDMPLPGNRPTGWEEEEDVEIGMWNS 1154
+ V AL K KSMQ+GW GD+M L ++ WE+EE +WN+
Sbjct: 850 EPPVAFGRAGAPVAASALCKPASKSMQEGWGSGGDEMNLSTSQ---WEDEEG---DVWNN 903
Query: 1155 NSSQELNSSLN-WPPYTKKMSSKGLSGKKRRRERGMMKGGNKQEEAWI-NPFVKQFSNIS 1212
+SQE SS + W KK KG MK KQ+EAWI + +KQ +++
Sbjct: 904 AASQESTSSCSSWGNAPKKGLQKG------------MKTSGKQDEAWIMSRLIKQLTDMG 951
Query: 1213 FSRDSPEENVQSNKMDLSGGM--LQDKRMEIDKHSLNIGDYNRTVGKGPGSRPQISKESS 1270
F R+ EE ++SN M+L M L +K++++DK L + D+N K G RP ISKESS
Sbjct: 952 FPREPAEEALKSNNMNLDQAMSALLEKKVDVDKRGLGVTDHNGMAAKPLGCRPPISKESS 1011
Query: 1271 MERNPYFDKDGIVADESQNMQFMSSQSMKLPPSNSALPNQALGSIA-GLGMQNLNSVRQ- 1328
++R + DKDG + +E F+ S S+KLP S+SALP+QALG IA GLGMQNLNS RQ
Sbjct: 1012 VDRPTFLDKDGGLVEEPTPSPFLPSPSLKLPLSHSALPSQALGGIASGLGMQNLNSSRQI 1071
Query: 1329 -NGNPSMFGVGNTAAQPRGMQQPP---AQPLSSSQPNLRAQVPPPLLSPQVPVSLLKYAP 1384
+GN MFG + AAQ R MQQPP QPL+SSQP+LRAQVP LSPQV LL++A
Sbjct: 1072 PSGNLGMFG-NSGAAQARTMQQPPQPPVQPLNSSQPSLRAQVPQ-FLSPQVQAQLLQFAA 1129
Query: 1385 NNGGLNPLF-----GPQQVAMLNQLSQLNQLSQISQLQRLLAQQQRAQSQRSVPSGNRPQ 1439
N GLNP PQ + MLNQL QL QL+ QRL QQQ Q+QR+V R Q
Sbjct: 1130 KNIGLNPALLTSPINPQHMTMLNQLYQL-QLAY----QRLQIQQQMLQAQRNVSGSMRQQ 1184
Query: 1440 QDQQGRPLS-VQQQMMQQSRQLDPNLLVKQQTPPSQQQ--PLHQPAMKSFLDNVMPHTT- 1495
+ Q R ++ +QQQ+ Q RQL LLVKQ PP LH A KS +D+ H
Sbjct: 1185 EQQVARTITNLQQQIQQHQRQLAQALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHPQT 1244
Query: 1496 ---PELQ--KGPSPINAFSNFPI-GLNSNLNVN-MDMN---SIKEP---QSRLRKWTTVD 1542
P+LQ + S N F+ +P+ GLN N+NVN MDM S+K+P QSRL +WT +
Sbjct: 1245 PGLPDLQTKEQQSSPNTFAPYPLAGLNPNMNVNSMDMTGGLSVKDPSQSQSRLPQWTHPN 1304
Query: 1543 SI----SVNTSLDQNSSKHGAISSGFRLE-------ESPFVPYDFMNSSTSPASPPGSIG 1591
S+ S + L+QN SKHGAI G + + + YD + +S SPASPP ++
Sbjct: 1305 SMDNLPSAASPLEQNPSKHGAIPGGLSIGPPGKSSIDDSYGRYDLIQNSESPASPPVAVP 1364
Query: 1592 DGWPRAKSPN----GSSSVNWPPEFRPGEPWKGYPNIDPETDPYVTPGSVINNLSINT-V 1646
W RAKS + SS+NWPPEF PG PWKG NIDPE DP VTPGSV +INT +
Sbjct: 1365 HSWSRAKSDSDKISNGSSINWPPEFHPGVPWKGLQNIDPENDPDVTPGSVPTGPTINTTI 1424
Query: 1647 REVDHLRDRNSGSSSSLNTTLPSTSAWSSIRASNYNVPLSSTAQSTSARNSDSKLTWSPG 1706
++V+ ++ G S + +T WSS P
Sbjct: 1425 QDVNRYLLKSGGKLSDIKST------WSS----------------------------GPT 1450
Query: 1707 SVTNTSLAHELWKVPLPPKNITAPSRPPPGLTGQKPPLSTWDNSPLRIGGGWGNSDARYT 1766
S T SL+HELWKVP +N TAP+RPPPGLT KP STW SPL GW +S Y+
Sbjct: 1451 SHTQASLSHELWKVP---RNSTAPTRPPPGLTNPKPS-STWGASPL----GWTSS---YS 1499
Query: 1767 PGSSWGESSSGRITNWLVLKNLTPQIDGSTLRTLCMQHGPLITFHLNLPHGNALVRYSSK 1826
GS+W +SGR ++WLVL+NLTPQIDGSTLRTLC+QHGPLITFHLNL GNA+VRYSSK
Sbjct: 1500 SGSAWSTDTSGRTSSWLVLRNLTPQIDGSTLRTLCLQHGPLITFHLNLTQGNAVVRYSSK 1559
Query: 1827 EEVVKAQKSLHMCVLGNTTILAEFASEEEISRFFAQSQSLTPSPGWQ-SLGSSQSRLGSL 1885
EE KAQKSLHMCVLGNTTILAEFA EEE++RF AQ Q+L P+ WQ S SSQ RL +
Sbjct: 1560 EEAAKAQKSLHMCVLGNTTILAEFAGEEEVNRFLAQGQALPPTSSWQSSSASSQPRLSAA 1619
Query: 1886 DCSHSFSSRTDLNHWNGAGLSGTNCGDLHGTSLW-GTPHYSTSLWGPPSSSDPRGISSPS 1944
SH R+D HWN L G +L LW G P YS+SLWGPPS+ D R I SP+
Sbjct: 1620 GSSHGL-VRSDAGHWNAPCLGGKGSSEL----LWGGVPQYSSSLWGPPSADDSRVIGSPT 1674
Query: 1945 PINAFLSVDHLGG 1957
P+ L D L G
Sbjct: 1675 PLTTLLPGDLLSG 1687
>gi|241982729 trinucleotide repeat containing 6B isoform 1 [Homo
sapiens]
Length = 1833
Score = 1100 bits (2846), Expect = 0.0
Identities = 775/2033 (38%), Positives = 1040/2033 (51%), Gaps = 298/2033 (14%)
Query: 22 QEEEQLMEEKKKKKDDKKKKEAAQKKATEQKIKVPEQIKPSVSQPQPANS-NNGTSTATS 80
+ EEQLME+KK+KK+DKKKKEA QK TEQK KVPE KPS+SQP A+ + S +
Sbjct: 7 EREEQLMEDKKRKKEDKKKKEATQK-VTEQKTKVPEVTKPSLSQPTAASPIGSSPSPPVN 65
Query: 81 TNNNAKRATANNQQPQQQQQQQQPQQQQPQQQPQPQPQQQQPQQQPQALPRYPREVPPRF 140
NNAKR N QP P A PREVPPRF
Sbjct: 66 GGNNAKRVAVPNGQP------------------------------PSAARYMPREVPPRF 95
Query: 141 R-HQEHKQLLKRGQHFPVIAANLGSAVKVLNSQSESSALTNQQPQNNGEVQNSKNQSDIN 199
R Q+HK LLKRGQ P LG NN +V + QS+
Sbjct: 96 RCQQDHKVLLKRGQPPPPSCMLLGGGA------GPPPCTAPGANPNNAQVTGALLQSESG 149
Query: 200 ---HSTSG----SHYENSQRGPVSS----TSDSSTNCKNAVVSDLSEKEAWPSAPGSDPE 248
ST G S+Y NS G +S TS + + + V+ D S+ E WP D E
Sbjct: 150 TAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASKDTE 209
Query: 249 LASE-CMDADSASSSESERNITIMASGNTGGEKDGLRNSTGLGSQNKFVVGSSSNNVGHG 307
+SE D +SAS+ SE++ G+T K G GSQ S + G+
Sbjct: 210 SSSENTTDNNSASNPGSEKS---TLPGSTTSNK-------GKGSQ------CQSASSGNE 253
Query: 308 SSTGPWGFSHGAIISTCQVSVDAPESKSESSNNRMNAWGTVSSSS--NGGLNPSTLNSAS 365
+ G W A SV + S +E +NN + W VS G S N S
Sbjct: 254 CNLGVWKSDPKA------KSVQSSNSTTE-NNNGLGNWRNVSGQDRIGPGSGFSNFNPNS 306
Query: 366 NHGAWPVLENNGLALKGPVGSGSSGINIQCSTIGQMPNNQSINSKVSGGSTHGTWGSLQE 425
N AWP L G + KG + + +S + Q ST+GQ S ++
Sbjct: 307 NPSAWPALVQEGTSRKGALETDNSNSSAQVSTVGQT--------------------SREQ 346
Query: 426 TCESEVSGTQKVSFSGQPQNITTEMTGP-NNTTNFMTSSLPNSGSVQNNELPSSNTGAWR 484
+ E +G V SG+ Q GP N TN + S PN P N G
Sbjct: 347 QSKMENAGVNFV-VSGREQAQIHNTDGPKNGNTNSLNLSSPN---------PMENKG--- 393
Query: 485 VSTMNHPQMQAPSGMNGTSLS----HLSNGESKSG--GSYGTTWGAYG----SNYSGDKC 534
M G+ TS S S G+ K+G GS+G G G S S
Sbjct: 394 --------MPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNSGN 445
Query: 535 SGPNGQANGDTVNATLMQPGVNGPMGTNFQVNTNKGGGVWESGAANSQSTSWGSGNGANS 594
+G NG+ D+ +Q G ++ N GG W G +S WG GN S
Sbjct: 446 NGNNGKEREDSWKGASVQKS-TGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTS 504
Query: 595 GGSRRGWGTPAQNTGTN-LPSVEWNKLPSNQHSNDSANGNGKTFTNGWKSTEEEDQGSAT 653
G S+ W P TG++ L EW+ P+ +S+ T W + ++
Sbjct: 505 GVSQGEWKQP---TGSDELKIGEWSG-PNQPNSS----------TGAWDN--QKGHPLPE 548
Query: 654 SQTNEQSSVWAKTGGTVESDGSTESTGRLEEKGTGESQSRDRRKI-----DQHTLLQSIV 708
+Q N Q+ W ++ + S+ +STG + G+ +S + RR D +LQ+++
Sbjct: 549 NQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLL 608
Query: 709 NRTDLDPRVLSNSGWGQTPIKQNTAWDTETSPRGERKTDNGTEAWGSSATQTFNSGACID 768
+RTDLDPRVLSN+GWGQT IKQ+T WD E PR E K+D GTE W S+ATQT NSG D
Sbjct: 609 SRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGD 668
Query: 769 KTSPNGNDTSSVSGWGDPKPALRWGDSKGSNCQGGWEDDSAATGMVKSNQWGNCKEEK-- 826
S SGWG+ + W D K + GGW D S+ WG + ++
Sbjct: 669 APS---QSNQMKSGWGELSASTEWKDPKNT---GGWNDYKNN----NSSNWGGGRPDEKT 718
Query: 827 -AAWNDSQKNKQGWGDGQKSSQGWSVSASDNWGETSRNNHWGEA--NKKSSSGGSDSDRS 883
++WN++ QGWG G++ +QGWS S N WGE K+S+ S + +
Sbjct: 719 PSSWNENPSKDQGWGGGRQPNQGWS----------SGKNGWGEEVDQTKNSNWESSASKP 768
Query: 884 VSGWNELGKTSSFTWGNNINPNNSS--GWDESSKPTPSQGWGDPPKSNQSLGWGDSSKPV 941
VSGW E G+ TWGN N + +S GW++ + S W + + S W +
Sbjct: 769 VSGWGEGGQNEIGTWGNGGNASLASKGGWEDCKR---SPAWNETGRQPNS--WNKQHQQQ 823
Query: 942 SSPDW--NKQQDIVGSWG----IPPATGKPPGTGWLGGPIPAPAKEEEPTGWEEPSPESI 995
P Q + GSWG PP +P + W GP PA K+EEP+GWEEPSP+SI
Sbjct: 824 QPPQQPPPPQPEASGSWGGPPPPPPGNVRPSNSSWSSGPQPATPKDEEPSGWEEPSPQSI 883
Query: 996 RRKMEIDDGTSAWGDPSKYNYKNVNMWNKNVPNGNSRSDQQAQVHQLLTPASAISNKEAS 1055
RKM+IDDGTSAWGDP+ YNYKNVN+W+KN G + + L TP +++K AS
Sbjct: 884 SRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREP-----NLPTP---MTSKSAS 935
Query: 1056 SGSGWGEPWGEPSTPATTVDNGTSAWGKPIDSGPSWGEPIAAASSTSTWGSSSVGPQALS 1115
W + + PA DNGTSAWG+P +S P WGE +ST+ WG++
Sbjct: 936 -------VWSKSTPPAP--DNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAM 986
Query: 1116 KSGPKSMQDGWCGDDMPLPGNRPTGWEEEEDVEIGMWNSNSSQELNSSLNWPPYTKKMSS 1175
K KSMQDGW D P+ G R WEEEED G+WN+ SQ SS N +S
Sbjct: 987 KPNSKSMQDGWGESDGPVTGARHPSWEEEEDG--GVWNTTGSQGSASSHN-------SAS 1037
Query: 1176 KGLSGKKRRRERGMMKGGNKQEEAWINPFVKQFSNISFSRDSPEENVQSNKMDLSGGMLQ 1235
G GKK+ + +KGGN ++W+NP KQFSN+ S E+ S+KMDLS G L
Sbjct: 1038 WGQGGKKQM--KCSLKGGN--NDSWMNPLAKQFSNMGLL--SQTEDNPSSKMDLSVGSLS 1091
Query: 1236 DKRMEIDKHSLNIGDYNRTVGKG-PGSRPQISKE-SSMERNPYFDK--------DGIVAD 1285
DK+ ++DK ++N+GD+N + K G RP SK+ + + PYF+K DG + D
Sbjct: 1092 DKKFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEKLTLPFSNQDGCLGD 1151
Query: 1286 ESQNMQFMSSQSMKLPPSNSALPNQALGSI-AGLGMQNLNSVRQNGNPSMFGVGNTAAQP 1344
E+ F S S KL PS S LPN +LG+I GL QN + RQ G+ +F GN+ AQ
Sbjct: 1152 EAPCSPFSPSPSYKLSPSGSTLPNVSLGAIGTGLNPQNF-AARQGGSHGLF--GNSTAQS 1208
Query: 1345 RGMQQPPAQPLSSSQPNLRAQVPPPLLSPQVPVSLLKYAPNNG------GLNPLFGPQQV 1398
RG+ P QPL+SS P+LRAQVPP +SPQV S+LK PN+G + P PQQ+
Sbjct: 1209 RGL-HTPVQPLNSS-PSLRAQVPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQI 1266
Query: 1399 AMLNQLSQLNQLSQISQLQRLLAQQQR---AQSQRSVPSGNRPQQDQQ-GRPLSVQQQMM 1454
AML+QL Q+ Q QL LL QQQ+ Q+QR + R QQ+QQ R +S QQ
Sbjct: 1267 AMLSQLPQIPQFQLACQL--LLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQ 1324
Query: 1455 QQSRQLDPNLLVKQQTPPSQQQPLHQPAMKSFLDNVMPHT----TPELQ-KGPSPINAFS 1509
QQ +Q+ P + P H K LDN++P+ P+LQ KGP P S
Sbjct: 1325 QQ----------QQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIP-GYGS 1373
Query: 1510 NFPIGLNSNLNVNMDMNSIKEPQSRLRKWTT-VDSISVNTSLDQNSSKHGAI-SSGFRLE 1567
F G ++ M +SR ++WT+ ++ + + + N K+GAI + G
Sbjct: 1374 GFSSG---GMDYGMVGGKEAGTESRFKQWTSMMEGLPSVATQEANMHKNGAIVAPGKTRG 1430
Query: 1568 ESPFVPYDFMNSSTSPASPPGSIGDGWPRAKSP------NGSSSVNWPPEFRPGEPWKGY 1621
SP+ +D + T G GD W AKSP + SS+ +WPPEF+PG PWKG
Sbjct: 1431 GSPYNQFDIIPGDTL-GGHTGPAGDSWLPAKSPPTNKIGSKSSNASWPPEFQPGVPWKGI 1489
Query: 1622 PNIDPETDPYVTPGSVINNLSINTVREVDH--LRDRNSGSSSSLNTTLPSTSAWSSIRAS 1679
NIDPE+DPYVTPGSV+ + + + + DH LRD +GS+SSLNT+LPS AW +
Sbjct: 1490 QNIDPESDPYVTPGSVLGGTATSPIVDTDHQLLRDNTTGSNSSLNTSLPSPGAWPYSASD 1549
Query: 1680 NYNVPLSSTAQSTSARNSDSKLTWSPGSVTN--TSLAHELWKVPLPPKNITAPSRPPPGL 1737
N + STSA+ D K TWSP + + T L++++WK + +N T RPPPGL
Sbjct: 1550 N----SFTNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNKMWKNHISSRNTTPLPRPPPGL 1605
Query: 1738 TGQKPPLSTWDNSPLRIGGGWGNSDARYTPGSSWGESSSGRITNWLVLKNLTPQIDGSTL 1797
T KP S W ++ R GWG D+R S+W + S R + WLVL NLTPQIDGSTL
Sbjct: 1606 TNPKPS-SPWSSTAPRSVRGWGTQDSRLASASTWSDGGSVRPSYWLVLHNLTPQIDGSTL 1664
Query: 1798 RTLCMQHGPLITFHLNLPHGNALVRYSSKEEVVKAQKSLHMCVLGNTTILAEFASEEEIS 1857
RT+CMQHGPL+TFHLNL G AL+RYS+K+E KAQ +LHMCVLGNTTILAEFA+++E+S
Sbjct: 1665 RTICMQHGPLLTFHLNLTQGTALIRYSTKQEAAKAQTALHMCVLGNTTILAEFATDDEVS 1724
Query: 1858 RFFAQSQSLT-------PSPGWQSLGSSQSRLGSL-DCSHSFSSRTDLNHWNGAGLSGTN 1909
RF AQ+Q T P+ GWQSL + Q++ + + F T L W+ + G++
Sbjct: 1725 RFLAQAQPPTPAATPSAPAAGWQSLETGQNQSDPVGPALNLFGGSTGLGQWSSSA-GGSS 1783
Query: 1910 CGDLHGTSLWGTPHYSTSLWGPPSSSDPRGISSPSPINAFLSVDHLGGGGESM 1962
DL G SLWG P+YS+SLWG P+ DP + SP+P+ L D LGGG +S+
Sbjct: 1784 GADLAGASLWGPPNYSSSLWGVPTVEDPHRMGSPAPL---LPGDLLGGGSDSI 1833
>gi|148491080 trinucleotide repeat containing 6B isoform 2 [Homo
sapiens]
Length = 1723
Score = 868 bits (2243), Expect = 0.0
Identities = 699/2043 (34%), Positives = 945/2043 (46%), Gaps = 428/2043 (20%)
Query: 22 QEEEQLMEEKKKKKDDKKKKEAAQKKATEQKIKVPEQIKPSVSQPQPANS-NNGTSTATS 80
+ EEQLME+KK+KK+DKKKKEA QK TEQK KVPE KPS+SQP A+ + S +
Sbjct: 7 EREEQLMEDKKRKKEDKKKKEATQK-VTEQKTKVPEVTKPSLSQPTAASPIGSSPSPPVN 65
Query: 81 TNNNAKRATANNQQPQQQQQQQQPQQQQPQQQPQPQPQQQQPQQQPQALPRYPREVPPRF 140
NNAKR N QP P A PREVPPRF
Sbjct: 66 GGNNAKRVAVPNGQP------------------------------PSAARYMPREVPPRF 95
Query: 141 R-HQEHKQLLKRGQHFPVIAANLGSAVKVLNSQSESSALTNQQPQNNGEVQNSKNQSDIN 199
R Q+HK LLKRGQ P LG + + N Q G + S++ + +
Sbjct: 96 RCQQDHKVLLKRGQPPPPSCMLLGGGAGPPPCTAPGANPNNAQV--TGALLQSESGTAPD 153
Query: 200 HSTSG---SHYENSQRGPVSS----TSDSSTNCKNAVVSDLSEKEAWPSAPGSDPELASE 252
+ G S+Y NS G +S TS + + + V+ D S+ E WP D E +SE
Sbjct: 154 STLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASKDTESSSE 213
Query: 253 -CMDADSASSSESERNITIMASGNTGGEKDGLRNSTGLGSQNKFVVGSSSNNVGHGSSTG 311
D +SAS+ SE++ G+T K G GSQ S + G+ + G
Sbjct: 214 NTTDNNSASNPGSEKSTL---PGSTTSNK-------GKGSQ------CQSASSGNECNLG 257
Query: 312 PWGFSHGAIISTCQVSVDAPESKSESSNNRMNAWGTVSSSSNGGLNP--STLNSASNHGA 369
W A SV + S +E+ NN + W VS G S N SN A
Sbjct: 258 VWKSDPKA------KSVQSSNSTTEN-NNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSA 310
Query: 370 WPVLENNGLALKGPVGSGSSGINIQCSTIGQMPNNQSINSKVSGGSTHGTWGSLQETCES 429
WP L G + KG + + +S + Q ST+GQ Q + +G
Sbjct: 311 WPALVQEGTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAG---------------- 354
Query: 430 EVSGTQKVSF--SGQPQNITTEMTGPNN-TTNFMTSSLPNSGSVQNNELPSSNTGAWRVS 486
V+F SG+ Q GP N TN + S PN P N G
Sbjct: 355 -------VNFVVSGREQAQIHNTDGPKNGNTNSLNLSSPN---------PMENKG----- 393
Query: 487 TMNHPQMQAPSGMNGTSLS----HLSNGESKSG--GSYGTTWGAYG----SNYSGDKCSG 536
M G+ TS S S G+ K+G GS+G G G S S +G
Sbjct: 394 ------MPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNSGNNG 447
Query: 537 PNGQANGDTVNATLMQPGVNGPMGTNFQVNTNKGGGVWESGAANSQSTSWGSGNGANSGG 596
NG+ D+ +Q G ++ N GG W G +S WG GN SG
Sbjct: 448 NNGKEREDSWKGASVQKST-GSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGV 506
Query: 597 SRRGWGTPAQNTGTN-LPSVEWNKLPSNQHSNDSANGNGKTFTNGWKSTEEEDQGSATSQ 655
S+ W P TG++ L EW+ P+ +S+ A N K E+QG+A
Sbjct: 507 SQGEWKQP---TGSDELKIGEWSG-PNQPNSSTGAWDNQKGHPL------PENQGNA--- 553
Query: 656 TNEQSSVWAKTGGTVESDGSTESTGRLEEKGTGESQSRDRRKI-----DQHTLLQSIVNR 710
Q+ W ++ + S+ +STG + G+ +S + RR D +LQ++++R
Sbjct: 554 ---QAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSR 610
Query: 711 TDLDPRVLSNSGWGQTPIKQNTAWDTETSPRGERKTDNGTEAWGSSATQTFNSGACIDKT 770
TDLDPRVLSN+GWGQT IKQ+T WD E PR E K+D GTE
Sbjct: 611 TDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTE------------------- 651
Query: 771 SPNGNDTSSVSGWGDPKPALRWGDSKGSNCQGGWEDDSAATGMVKSNQWGNCKEEKAAWN 830
GWE SAAT S WG+ +
Sbjct: 652 --------------------------------GWE--SAATQTKNSGGWGDAPSQ----- 672
Query: 831 DSQKNKQGWGDGQKSSQGWSVSASDNWGETSRNNHWGEANKKSSS---GGSDSDRSVSGW 887
S + K GWG+ +SAS W + W + +SS GG +++ S W
Sbjct: 673 -SNQMKSGWGE---------LSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPSSW 722
Query: 888 NELGKTSSFTWGNNINPNNSSGWDESSKPTPSQGWGDPPKSNQSLGWGDS-SKPVSSPDW 946
NE + WG PN GW GWG+ ++ W S SKPVS W
Sbjct: 723 NE-NPSKDQGWGGGRQPNQ--GWSSGKN-----GWGEEVDQTKNSNWESSASKPVSG--W 772
Query: 947 NKQ-QDIVGSWGIPPATGKPPGTGWLGGPIPAPAKEE---EPTGW----------EEPSP 992
+ Q+ +G+WG GW +PA E +P W ++P P
Sbjct: 773 GEGGQNEIGTWGNGGNASLASKGGWEDCK-RSPAWNETGRQPNSWNKQHQQQQPPQQPPP 831
Query: 993 ESIRRKMEIDDGTSAWGDPSKYNYKNVNMWNKNVPNGNSRSDQQAQVHQLLTPASAISNK 1052
+ + +WG P NV N + +G P A
Sbjct: 832 PQ-------PEASGSWGGPPPPPPGNVRPSNSSWSSG---------------PQPATPKD 869
Query: 1053 EASSGSGWGEPWGEPSTPATTVDNGTSAWGKP--------------IDSGPSWGEPIAAA 1098
E SG W EP + + +D+GTSAWG P GP+ EP
Sbjct: 870 EEPSG--WEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLPT 927
Query: 1099 SSTSTWGSSSVGPQALSKSGPKSMQDGWCGDDMPLPGNRPTGWEEEEDVEIGMWNSNSSQ 1158
TS S S KSMQDGW D P+ G R WEEEED G+WN+ SQ
Sbjct: 928 PMTSKSASDS-----------KSMQDGWGESDGPVTGARHPSWEEEEDG--GVWNTTGSQ 974
Query: 1159 ELNSSLNWPPYTKKMSSKGLSGKKRRRERGMMKGGNKQEEAWINPFVKQFSNISFSRDSP 1218
SS N +S G GKK+ + +KGGN ++W+NP KQFSN+ S
Sbjct: 975 GSASSHN-------SASWGQGGKKQMK--CSLKGGNN--DSWMNPLAKQFSNMGLL--SQ 1021
Query: 1219 EENVQSNKMDLSGGMLQDKRMEIDKHSLNIGDYNRTVGKG-PGSRPQISKE-SSMERNPY 1276
E+ S+KMDLS G L DK+ ++DK ++N+GD+N + K G RP SK+ + + PY
Sbjct: 1022 TEDNPSSKMDLSVGSLSDKKFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPY 1081
Query: 1277 FDKDGIVADESQNMQFMSSQSMKLPPSNSALPNQALGSIAGLGMQNLNSVRQNGNPSMFG 1336
F+K G+ +FG
Sbjct: 1082 FEK-------------------------------------------------GGSHGLFG 1092
Query: 1337 VGNTAAQPRGMQQPPAQPLSSSQPNLRAQVPPPLLSPQVPVSLLKYAPNNG------GLN 1390
N+ AQ RG+ P QPL+SS P+LRAQVPP +SPQV S+LK PN+G +
Sbjct: 1093 --NSTAQSRGLHTP-VQPLNSS-PSLRAQVPPQFISPQVSASMLKQFPNSGLSPGLFNVG 1148
Query: 1391 PLFGPQQVAMLNQLSQLNQLSQISQLQRLLAQQQRAQ---SQRSVPSGNRPQQDQQ-GRP 1446
P PQQ+AML+QL Q+ Q QL LL QQQ+ Q +QR + R QQ+QQ R
Sbjct: 1149 PQLSPQQIAMLSQLPQIPQFQLACQL--LLQQQQQQQLLQNQRKISQAVRQQQEQQLARM 1206
Query: 1447 LSVQQQMMQQSRQLDPNLLVKQQTPPSQQQPLHQPAMKSFLDNVMPHTT----PELQ-KG 1501
+S QQ QQ +Q+ P + P H K LDN++P+ P+LQ KG
Sbjct: 1207 VSALQQQQQQ----------QQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKG 1256
Query: 1502 PSPINAFSNFPIGLNSNLNVNMDMNSIKEP--QSRLRKWTTV-DSISVNTSLDQNSSKHG 1558
P P + G +S ++ M KE +SR ++WT++ + + + + N K+G
Sbjct: 1257 PIP-----GYGSGFSSG-GMDYGMVGGKEAGTESRFKQWTSMMEGLPSVATQEANMHKNG 1310
Query: 1559 AI-SSGFRLEESPFVPYDFMNSSTSPASPPGSIGDGWPRAKSP------NGSSSVNWPPE 1611
AI + G SP+ +D + T G GD W AKSP + SS+ +WPPE
Sbjct: 1311 AIVAPGKTRGGSPYNQFDIIPGDTL-GGHTGPAGDSWLPAKSPPTNKIGSKSSNASWPPE 1369
Query: 1612 FRPGEPWKGYPNIDPETDPYVTPGSVINNLSINTVREVDH--LRDRNSGSSSSLNTTLPS 1669
F+PG PWKG NIDPE+DPYVTPGSV+ + + + + DH LRD +GS+SSLNT+LPS
Sbjct: 1370 FQPGVPWKGIQNIDPESDPYVTPGSVLGGTATSPIVDTDHQLLRDNTTGSNSSLNTSLPS 1429
Query: 1670 TSAWSSIRASNYNVPLSSTAQSTSARNSDSKLTWSPGSVTN--TSLAHELWKVPLPPKNI 1727
AW + N + STSA+ D K TWSP + + T L++++WK + +N
Sbjct: 1430 PGAWPYSASDNS----FTNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNKMWKNHISSRNT 1485
Query: 1728 TAPSRPPPGLTGQKPPLSTWDNSPLRIGGGWGNSDARYTPGSSWGESSSGRITNWLVLKN 1787
T RPPPGLT KP S W ++ R GWG D+R S+W + S R + WLVL N
Sbjct: 1486 TPLPRPPPGLTNPKPS-SPWSSTAPRSVRGWGTQDSRLASASTWSDGGSVRPSYWLVLHN 1544
Query: 1788 LTPQIDGSTLRTLCMQHGPLITFHLNLPHGNALVRYSSKEEVVKAQKSLHMCVLGNTTIL 1847
LTPQIDGSTLRT+CMQHGPL+TFHLNL G AL+RYS+K+E KAQ +LHMCVLGNTTIL
Sbjct: 1545 LTPQIDGSTLRTICMQHGPLLTFHLNLTQGTALIRYSTKQEAAKAQTALHMCVLGNTTIL 1604
Query: 1848 AEFASEEEISRFFAQSQSLT-------PSPGWQSLGSSQSRLGSL-DCSHSFSSRTDLNH 1899
AEFA+++E+SRF AQ+Q T P+ GWQSL + Q++ + + F T L
Sbjct: 1605 AEFATDDEVSRFLAQAQPPTPAATPSAPAAGWQSLETGQNQSDPVGPALNLFGGSTGLGQ 1664
Query: 1900 WNGAGLSGTNCGDLHGTSLWGTPHYSTSLWGPPSSSDPRGISSPSPINAFLSVDHLGGGG 1959
W+ + G++ DL G SLWG P+YS+SLWG P+ DP + SP+P+ L D LGGG
Sbjct: 1665 WSSSA-GGSSGADLAGASLWGPPNYSSSLWGVPTVEDPHRMGSPAPL---LPGDLLGGGS 1720
Query: 1960 ESM 1962
+S+
Sbjct: 1721 DSI 1723
>gi|67782330 trinucleotide repeat containing 6B isoform 3 [Homo
sapiens]
Length = 1029
Score = 606 bits (1562), Expect = e-173
Identities = 388/946 (41%), Positives = 523/946 (55%), Gaps = 137/946 (14%)
Query: 1056 SGSGWGEPWGEPSTPATTVDNGTSAWGKPIDSGPSWGEPIAAASSTSTWGSSSVGPQALS 1115
S SG W + + PA DNGTSAWG+P +S P WGE +ST+ WG++
Sbjct: 182 SESGTAPVWSKSTPPAP--DNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAM 239
Query: 1116 KSGPKSMQDGWCGDDMPLPGNRPTGWEEEEDVEIGMWNSNSSQELNSSLNWPPYTKKMSS 1175
K KSMQDGW D P+ G R WEEEED G+WN+ SQ SS N +S
Sbjct: 240 KPNSKSMQDGWGESDGPVTGARHPSWEEEEDG--GVWNTTGSQGSASSHN-------SAS 290
Query: 1176 KGLSGKKRRRERGMMKGGNKQEEAWINPFVKQFSNISFSRDSPEENVQSNKMDLSGGMLQ 1235
G GKK+ + +KGGN ++W+NP KQFSN+ S E+ S+KMDLS G L
Sbjct: 291 WGQGGKKQMK--CSLKGGNN--DSWMNPLAKQFSNMGLL--SQTEDNPSSKMDLSVGSLS 344
Query: 1236 DKRMEIDKHSLNIGDYNRTVGKG-PGSRPQISKE-SSMERNPYFDKDGIVADESQNMQFM 1293
DK+ ++DK ++N+GD+N + K G RP SK+ + + PYF+K
Sbjct: 345 DKKFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEK-------------- 390
Query: 1294 SSQSMKLPPSNSALPNQALGSIAGLGMQNLNSVRQNGNPSMFGVGNTAAQPRGMQQPPAQ 1353
G+ +FG N+ AQ RG+ P Q
Sbjct: 391 -----------------------------------GGSHGLFG--NSTAQSRGLHTP-VQ 412
Query: 1354 PLSSSQPNLRAQVPPPLLSPQVPVSLLKYAPNNG------GLNPLFGPQQVAMLNQLSQL 1407
PL+SS P+LRAQVPP +SPQV S+LK PN+G + P PQQ+AML+QL Q+
Sbjct: 413 PLNSS-PSLRAQVPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQI 471
Query: 1408 NQLSQISQLQRLLAQQQRAQ---SQRSVPSGNRPQQDQQ-GRPLSVQQQMMQQSRQLDPN 1463
Q QL LL QQQ+ Q +QR + R QQ+QQ R +S QQ QQ
Sbjct: 472 PQFQLACQL--LLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQ------- 522
Query: 1464 LLVKQQTPPSQQQPLHQPAMKSFLDNVMPHTT----PELQ-KGPSPINAFSNFPIGLNSN 1518
+Q+ P + P H K LDN++P+ P+LQ KGP P + G +S
Sbjct: 523 ---QQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIP-----GYGSGFSSG 574
Query: 1519 LNVNMDMNSIKEP--QSRLRKWTTV-DSISVNTSLDQNSSKHGAI-SSGFRLEESPFVPY 1574
++ M KE +SR ++WT++ + + + + N K+GAI + G SP+ +
Sbjct: 575 -GMDYGMVGGKEAGTESRFKQWTSMMEGLPSVATQEANMHKNGAIVAPGKTRGGSPYNQF 633
Query: 1575 DFMNSSTSPASPPGSIGDGWPRAKSP------NGSSSVNWPPEFRPGEPWKGYPNIDPET 1628
D + T G GD W AKSP + SS+ +WPPEF+PG PWKG NIDPE+
Sbjct: 634 DIIPGDTL-GGHTGPAGDSWLPAKSPPTNKIGSKSSNASWPPEFQPGVPWKGIQNIDPES 692
Query: 1629 DPYVTPGSVINNLSINTVREVDH--LRDRNSGSSSSLNTTLPSTSAWSSIRASNYNVPLS 1686
DPYVTPGSV+ + + + + DH LRD +GS+SSLNT+LPS AW + N
Sbjct: 693 DPYVTPGSVLGGTATSPIVDTDHQLLRDNTTGSNSSLNTSLPSPGAWPYSASDNS----F 748
Query: 1687 STAQSTSARNSDSKLTWSPGSVTN--TSLAHELWKVPLPPKNITAPSRPPPGLTGQKPPL 1744
+ STSA+ D K TWSP + + T L++++WK + +N T RPPPGLT KP
Sbjct: 749 TNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNKMWKNHISSRNTTPLPRPPPGLTNPKPS- 807
Query: 1745 STWDNSPLRIGGGWGNSDARYTPGSSWGESSSGRITNWLVLKNLTPQIDGSTLRTLCMQH 1804
S W ++ R GWG D+R S+W + S R + WLVL NLTPQIDGSTLRT+CMQH
Sbjct: 808 SPWSSTAPRSVRGWGTQDSRLASASTWSDGGSVRPSYWLVLHNLTPQIDGSTLRTICMQH 867
Query: 1805 GPLITFHLNLPHGNALVRYSSKEEVVKAQKSLHMCVLGNTTILAEFASEEEISRFFAQSQ 1864
GPL+TFHLNL G AL+RYS+K+E KAQ +LHMCVLGNTTILAEFA+++E+SRF AQ+Q
Sbjct: 868 GPLLTFHLNLTQGTALIRYSTKQEAAKAQTALHMCVLGNTTILAEFATDDEVSRFLAQAQ 927
Query: 1865 SLT-------PSPGWQSLGSSQSRLGSL-DCSHSFSSRTDLNHWNGAGLSGTNCGDLHGT 1916
T P+ GWQSL + Q++ + + F T L W+ + G++ DL G
Sbjct: 928 PPTPAATPSAPAAGWQSLETGQNQSDPVGPALNLFGGSTGLGQWSSSA-GGSSGADLAGA 986
Query: 1917 SLWGTPHYSTSLWGPPSSSDPRGISSPSPINAFLSVDHLGGGGESM 1962
SLWG P+YS+SLWG P+ DP + SP+P+ L D LGGG +S+
Sbjct: 987 SLWGPPNYSSSLWGVPTVEDPHRMGSPAPL---LPGDLLGGGSDSI 1029
Score = 102 bits (253), Expect = 5e-21
Identities = 140/505 (27%), Positives = 188/505 (37%), Gaps = 135/505 (26%)
Query: 5 EAKATKDVERNLSRDLVQEEEQLMEEKKKKKDDKKKKEAAQKKATEQKIKVPEQIKPSVS 64
E+K K+ ER EEQLME+KK+KK+DKKKKEA QK TEQK KVPE KPS+S
Sbjct: 35 ESKQEKEQER---------EEQLMEDKKRKKEDKKKKEATQK-VTEQKTKVPEVTKPSLS 84
Query: 65 QPQPANS-NNGTSTATSTNNNAKRATANNQQPQQQQQQQQPQQQQPQQQPQPQPQQQQPQ 123
QP A+ + S + NNAKR N QP
Sbjct: 85 QPTAASPIGSSPSPPVNGGNNAKRVAVPNGQP---------------------------- 116
Query: 124 QQPQALPRYPREVPPRFR-HQEHKQLLKRGQHFPVIAANLGSAVKVLNSQSESSALTNQQ 182
P A PREVPPRFR Q+HK LLKRGQ P LG
Sbjct: 117 --PSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGGA------GPPPCTAPGA 168
Query: 183 PQNNGEVQNSKNQSDINHSTSGSHYENSQRGPVSSTSDSSTNCKNAVVSDLSEKEAWPSA 242
NN +V + QS+ S PV S S P A
Sbjct: 169 NPNNAQVTGALLQSE------------SGTAPVWSKST-------------------PPA 197
Query: 243 PGSDPELASECMDADSASSSESERNITIMASG---NTGGEKDGLRNSTGLGSQNKFVVGS 299
P D+ +S+ E N + G +TG G N T + N S
Sbjct: 198 P-------------DNGTSAWGEPNESSPGWGEMDDTGASTTGWGN-TPANAPNAMKPNS 243
Query: 300 SSNNVGHGSSTGP-WGFSHGAIISTCQVSV-DAPESKSESSNNRMNAWG-----TVSSSS 352
S G G S GP G H + V + S+ +S++ +WG + S
Sbjct: 244 KSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSL 303
Query: 353 NGGLNPSTLN----SASNHGAWPVLENNGLALK----GPVGSGSSGINIQCSTIGQM--- 401
GG N S +N SN G E+N + G + ++ + +G
Sbjct: 304 KGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSDKKFDVDKRAMNLGDFNDI 363
Query: 402 ----------PNNQSINSKVSG-----GSTHGTWGSLQETCESEVSGTQKVSFSGQPQ-- 444
PN++ + + SG G +HG +G+ T +S T + P
Sbjct: 364 MRKDRSGFRPPNSKDMGTTDSGPYFEKGGSHGLFGN--STAQSRGLHTPVQPLNSSPSLR 421
Query: 445 -NITTEMTGPNNTTNFMTSSLPNSG 468
+ + P + + M PNSG
Sbjct: 422 AQVPPQFISPQVSAS-MLKQFPNSG 445
Score = 43.1 bits (100), Expect = 0.003
Identities = 38/132 (28%), Positives = 49/132 (37%), Gaps = 22/132 (16%)
Query: 734 WDTETSPRGERKTDNGTEAWGSSATQTFNSGACIDKTSPNGNDTSSVSGWGD-PKPALRW 792
W T P DNGT AWG + G +D T +S +GWG+ P A
Sbjct: 190 WSKSTPPA----PDNGTSAWGEPNESSPGWGE-MDDTG------ASTTGWGNTPANAPNA 238
Query: 793 GDSKGSNCQGGW-EDDSAATGMVKSNQWGNCKEEKAAWND-------SQKNKQGWGDGQK 844
+ Q GW E D TG + W +E+ WN S N WG G K
Sbjct: 239 MKPNSKSMQDGWGESDGPVTG-ARHPSWEE-EEDGGVWNTTGSQGSASSHNSASWGQGGK 296
Query: 845 SSQGWSVSASDN 856
S+ +N
Sbjct: 297 KQMKCSLKGGNN 308
Score = 41.2 bits (95), Expect = 0.010
Identities = 38/172 (22%), Positives = 64/172 (37%), Gaps = 42/172 (24%)
Query: 866 WGEANKKSSSGGSDSDRSVSGWNELGKTSSFTWGNNINPNNSSGWDESSKPTPSQGWGDP 925
WGE N+ S GW E+ T + T G P N+ + KP
Sbjct: 205 WGEPNESSP-----------GWGEMDDTGASTTGWGNTPANA---PNAMKPN-------- 242
Query: 926 PKSNQSLGWGDSSKPVSS---PDWNKQQDIVGSWGIPPATGKPPGTGWLGGPIPAPAKEE 982
KS Q GWG+S PV+ P W +++D G W + G A
Sbjct: 243 SKSMQD-GWGESDGPVTGARHPSWEEEED-GGVWNTTGSQGS--------------ASSH 286
Query: 983 EPTGWEEPSPESIRRKMEIDDGTSAWGDPSKYNYKNVNMWNKNVPNGNSRSD 1034
W + + ++ ++ +W +P + N+ + ++ N +S+ D
Sbjct: 287 NSASWGQGGKKQMKCSLK-GGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMD 337
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 113 bits (283), Expect = 2e-24
Identities = 153/730 (20%), Positives = 291/730 (39%), Gaps = 40/730 (5%)
Query: 170 NSQSESSALTNQQPQNNGEVQNSKNQSDINHSTSGSHYENSQRGPVSSTSDSSTNCKNAV 229
+ S+SS ++ ++ + +SK++SD + S S S +S S SDSS + ++
Sbjct: 605 SDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSN 664
Query: 230 VSDLSEK-EAWPSAPGSDPELASECMDA-DSASSSESERNITIMASGNTGGEKDGLRNST 287
SD S+ ++ S+ SD +S+ D+ DS++SSES + S ++ NS+
Sbjct: 665 SSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSS 724
Query: 288 GLGSQNKFVVGSSSNNVGHGSSTGPWGFSHGAIISTCQVSVDAPESKSESSNNRMNAWGT 347
S N SSN+ S S S D+ +S S+SSN+ ++ +
Sbjct: 725 DSDSSNSSDSSDSSNSSDSSDS------------SDSSNSSDSSDS-SDSSNSSDSSDSS 771
Query: 348 VSSSSNGGLNPSTLNSASNHGAWPVLENNGLALKGPVGSGSSGINIQCSTIGQMPNNQSI 407
SS S+ N S N +SN N+ + S SS + S+ +N S
Sbjct: 772 DSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSD 831
Query: 408 NSKVSGGSTHGTWGSLQETCESEVSGTQKVSFSGQPQNITTEMTGPNNTTNFMTSSLPNS 467
+S S S + +S+ S S S +++ + +N+++ SS N
Sbjct: 832 SSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSD----SSDSSDSSNSSDSSDSSDSNE 887
Query: 468 GSVQNNELPSSNTGAWRVSTMNHPQMQAPSGMNGTSLSHLSNGESKSGGSYGTTWGAYGS 527
S ++ SSN+ S ++ + S N + S SN S S + + S
Sbjct: 888 SSNSSDSSDSSNSSDSDSSDSSNSSDSSDSS-NSSDSSESSNSSDNSNSSDSS--NSSDS 944
Query: 528 NYSGDKCSGPNGQANGDTVNATLMQPGVNGPMGTNFQVNTNKGGGVWESGAANSQSTSWG 587
+ S D + + + D+ N++ + ++ ++N S +++S +S
Sbjct: 945 SDSSDSSNSSDSSNSSDSSNSS----DSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDS 1000
Query: 588 SGNGANSGGSRRGWGTPAQNTGTNLPSVEWNKLPSNQHSNDSANGNGKTFTNGWKSTEEE 647
S + +S S + + ++ + S + + S+DS++ + + ++ ++ +
Sbjct: 1001 SNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS 1060
Query: 648 DQGSATSQTNEQSSVWAKTGGTVESDGSTESTGRLEEKGTGESQSRDRRKIDQHTLLQSI 707
S +S +++ S + + SD S S + S S D +
Sbjct: 1061 SDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1120
Query: 708 VNRTDLDPRVLSNSGWGQTPIKQNTAWDTETSPRGERKTDNGTEAWGSSATQTFNSGACI 767
N +D S+S + + D+ S +D+ + S ++ + +S
Sbjct: 1121 SNSSD-----SSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSS 1175
Query: 768 DKTSPNGNDTSSVSGWGDPKPALRWGDSKGSNCQGGWEDDSAATGMVKSNQWGNCKEEKA 827
D S N +D+S S D + DS S+ D S ++ S+ + +
Sbjct: 1176 D--SSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS-- 1231
Query: 828 AWNDSQKNKQGWGDGQKSSQGWSVSASDNWGETSRNNHWGEANKKSSSG---GSDSDRSV 884
N+S + S+ S +SD+ TS +N ++ KS +G GSDSD
Sbjct: 1232 --NESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDS 1289
Query: 885 SGWNELGKTS 894
G + TS
Sbjct: 1290 EGSDSNHSTS 1299
Score = 112 bits (281), Expect = 3e-24
Identities = 153/792 (19%), Positives = 310/792 (39%), Gaps = 31/792 (3%)
Query: 170 NSQSESSALTNQ-QPQNNGEVQNSKN-QSDINHSTSGSHYENSQRGPVSSTSDSSTNCKN 227
NS S A N + ++NG +SK + D + STS ++ +S + D+ +
Sbjct: 484 NSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSG 543
Query: 228 AVVSDLSEKEAWPSAPGSDPELASECMDADSASSSESERNITIMASGNTGGEKDGLRNST 287
SD S+ ++ S+ SD +S+ +DS SSS+S+ + + + + D +S
Sbjct: 544 KGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSD 603
Query: 288 GLGSQNKFVVGSSSNNVGHGSSTGPWGFSHGAIISTCQVSVDAPESKSESSNNRMNAWGT 347
S + SS++ S+ S + + + S S SS++ N+ +
Sbjct: 604 SSDSSD------SSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSS 657
Query: 348 VSSSSNGGLNPSTLNSASNHGAWPVLENNGLALKGPVGSGSSGINIQCSTIGQMPNNQSI 407
SS+S+ + S + +S+ + N+ + S SS + S ++ S
Sbjct: 658 DSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSS----ESSDSSDSSDSDSS 713
Query: 408 NSKVSGGSTHGTWGSLQETCESEVSGTQKVSFSGQPQNI--TTEMTGPNNTTNFMTSSLP 465
+S S S S + S+ S + S S N +++ + +N+++ SS
Sbjct: 714 DSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDS 773
Query: 466 NSGSVQNNELPSSNTGAWRVSTMNHPQMQAPSGMNGTSLSHLSNGESKSGGSYGTTWGAY 525
+ S +N S+++ S+ + + + + + S S+ +S + + +
Sbjct: 774 SDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSS 833
Query: 526 GSNYSGDKCSGPNGQANGDTVNATLMQPGVNGPMGTNFQVNTNKGGGVWESGAANSQSTS 585
S+ S D S + ++G +++ N ++ ++N +S +N S S
Sbjct: 834 DSSNSSDS-SDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSS-DSSDSNESSNS 891
Query: 586 WGSGNGANSGGSRRGWGTPAQNTGTNLPSVEWNKLPSNQHSNDSANGNGKTFTNGWKSTE 645
S + +NS S + ++ ++ S N S++ SN S N N +N S++
Sbjct: 892 SDSSDSSNSSDS-----DSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSD 946
Query: 646 EEDQGSATSQTNEQSSVWAKTGGTVESDGSTESTGRLEEKGTGESQSRDRRKIDQHTLLQ 705
D +++ +N S + S S++S+ + + +S D
Sbjct: 947 SSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSS----DSSDSSN 1002
Query: 706 SIVNRTDLDPRVLSNSGWGQTPIKQNTAWDTETSPRGERKTDNGTEAWGSSATQTFNSGA 765
S + D SNS + + D+ S +D+ + S ++ + +S
Sbjct: 1003 SSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD 1062
Query: 766 CIDKT----SPNGNDTSSVSGWGDPKPALRWGDSKGSNCQGGWEDDSAATGMVKSNQWGN 821
D + S + +D+S S D + DS S+ D S ++ S+ N
Sbjct: 1063 SSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSN 1122
Query: 822 CKE--EKAAWNDSQKNKQGWGDGQKSSQGWSVSASDNWGETSRNNHWGEANKKSSSGGSD 879
+ + + +DS + S S +SD+ + ++ ++ SS SD
Sbjct: 1123 SSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSD 1182
Query: 880 SDRSVSGWNELGKTSSFTWGNNINPNNSSGWDESSKPTPSQGWGDPPKSNQSLGWGDSSK 939
S S + + S ++ + ++SS +SS + S D SN+S DSS
Sbjct: 1183 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSD 1242
Query: 940 PVSSPDWNKQQD 951
S + + D
Sbjct: 1243 SSDSSNSSDSSD 1254
Score = 111 bits (278), Expect = 6e-24
Identities = 152/783 (19%), Positives = 307/783 (39%), Gaps = 37/783 (4%)
Query: 170 NSQSESSALTN-----QQPQNNGEVQNSKNQSDINHSTS--GSHYENSQRGPVSSTSDSS 222
+S S+SS +N ++ NS + SD + S S S ++S S +SDSS
Sbjct: 549 SSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSS 608
Query: 223 TNCKNAVVSDLSEKEAWPSAPGSDPELASECMDADSASSSESERNITIMASGNTGGEKDG 282
+ ++ SD S+ ++ S SD + D+ ++SS+S N S N+ D
Sbjct: 609 DSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDS 668
Query: 283 LRNSTGLGSQNKFVVGSSSNNVGHGSSTGPWGFSHGAIISTCQVSVDAPESKSESSNNRM 342
+S S + S S+N S + S + S+ D+ +S S++N
Sbjct: 669 SDSSDSSDSSS----SSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSS 724
Query: 343 NAWGTVSSSSNGGLNPSTLNSASNHGAWPVLENNGLALKGPVGSGSSGINIQCSTIGQMP 402
++ + SS S+ N S + +S+ ++ + S SS + +
Sbjct: 725 DSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD 784
Query: 403 NNQSINSKVSGGSTHGTWGSLQETCESEVSGTQKVSFSGQPQNITTEMTGPNNTTNFMTS 462
+N S NS S S++ + S + S + + +++ + +N+++ S
Sbjct: 785 SNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDS 844
Query: 463 SLPNSGSVQNNELPSSNTGAWRVSTMNHPQMQAPSGMNGTSLSHLSNGESKSGGSYGTTW 522
S + GS + SSN R + N S + +S S S+ ++S S ++
Sbjct: 845 SDSSDGS----DSDSSN----RSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSD 896
Query: 523 GAYGSNYSGDKCSGPNGQANGDTVNATLMQPGVNGPMGTNFQVNTNKGGGVWESGAANSQ 582
+ S+ D N + D+ N++ N +N ++N S ++NS
Sbjct: 897 SSNSSD--SDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSS 954
Query: 583 STSWGSGNGANSGGSRRGWGTPAQNTGTNLPSVEWNKLPSNQHSNDSANGNGKTFTNGWK 642
+S S + +NS S + + ++ + S + + + S+DS+N + +
Sbjct: 955 DSS-NSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSS-----D 1008
Query: 643 STEEEDQGSATSQTNEQSSVWAKTGGTVESDGSTESTGRLEEKGTGESQSRDRRKIDQHT 702
S++ D +++ +N S + + + +S S++S+ + + +S + D
Sbjct: 1009 SSDSSDSSNSSDSSNSSDS--SNSSDSSDSSDSSDSSDSSDSSDSSDSSNSS----DSSD 1062
Query: 703 LLQSIVNRTDLDPRVLSNSGWGQTPIKQNTAWDTETSPRGERKTDNGTEAWGSSATQTFN 762
S + D S+S + + D+ S +D+ + S ++ + N
Sbjct: 1063 SSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSN 1122
Query: 763 SGACIDKTSPNGNDTSSVSGWGDPKPALRWGDSKGSNCQGGWEDDSAATGMVKSNQWGNC 822
S D S + +D+S S D + DS S+ D S ++ S+ N
Sbjct: 1123 SSDSSD--SSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1180
Query: 823 KEEKAAWNDSQKNKQGWGDGQKSSQGWSVSASDNWGETSRNNHWGEANKKSSSGGSDSDR 882
+ + + S + D SS S S + ++S ++ +++ S S S
Sbjct: 1181 SDSSDSSDSSDSSDS--SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSS 1238
Query: 883 SVSGWNELGKTSSFTWGNNINPNNSSGWDESSKPTPSQGWGDPPKSNQSLGWGDSSKPVS 942
S ++ +S + ++ + + S DES + S + + S G S +
Sbjct: 1239 DSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHST 1298
Query: 943 SPD 945
S D
Sbjct: 1299 SDD 1301
Score = 111 bits (277), Expect = 8e-24
Identities = 146/778 (18%), Positives = 299/778 (38%), Gaps = 41/778 (5%)
Query: 170 NSQSESSALTNQQPQNNGEVQNSKNQSDINHSTSGSHYENSQRGPVSSTSDSSTNCKNAV 229
NS S + + +N + + SD + S+ ++S S +SDSS + ++
Sbjct: 559 NSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSD 618
Query: 230 VSDLSEKEAWPSAPGSDPELASECMDADSASSSESERNITIMASGNTGGEKDGLRNSTGL 289
SD + + SD + S+ D++S+ SS++ + S N+ D +S
Sbjct: 619 SSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSS 678
Query: 290 GSQNKFVVGSSSNNVGHGSSTGPWGFSHGAIISTCQVSVDAPESKSESSNNRMNAWGTVS 349
S S S+N S + S + S+ D+ +S S++N ++ + S
Sbjct: 679 SS-------SDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNS 731
Query: 350 SSSNGGLNPSTLNSASNHGAWPVLENNGLALKGPVGSGSSGINIQCSTIGQMPNNQSINS 409
S S+ N S + +S+ ++ + S SS + + +N S NS
Sbjct: 732 SDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNS 791
Query: 410 KVSGGSTHGTWGSLQETCESEVSGTQKVSFSGQPQNITTEMTGPNNTTNFMTSSLPNSGS 469
S S++ + S + S + + +++ + +N+++ SS + GS
Sbjct: 792 SDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGS 851
Query: 470 VQNNELPSSNTGAWRVSTMNHPQMQAPSGMNGTSLSHLSNGESKSGGSYGTTWGAYGSNY 529
+ SSN R + N S + +S S S+ ++S S ++ + S+
Sbjct: 852 ----DSDSSN----RSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSD- 902
Query: 530 SGDKCSGPNGQANGDTVNATLMQPGVNGPMGTNFQVNTNKGGGVWESGAANSQSTSWGSG 589
D N + D+ N++ N +N ++N S ++NS +S S
Sbjct: 903 -SDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSS-NSS 960
Query: 590 NGANSGGSRRGWGTPAQNTGTNLPSVEWNKLPSNQHSNDSANGNGKTFTNGWKSTEEEDQ 649
+ +NS S + + ++ + S + + + S+DS+N + + S++ D
Sbjct: 961 DSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSS-----DSSDSSDS 1015
Query: 650 GSATSQTNEQSSVWAKTGGTVESDGSTESTGRLEEKGTGESQSRDRRKIDQHTLLQSIVN 709
+++ +N S + + + +S S++S+ + + +S + D S +
Sbjct: 1016 SNSSDSSNSSDS--SNSSDSSDSSDSSDSSDSSDSSDSSDSSNSS----DSSDSSDSSDS 1069
Query: 710 RTDLDPRVLSNSGWGQTPIKQNTAWDTETSPRGERKTDNGTEAWGSSATQTFNSGACIDK 769
D S+S + + D+ S +D+ + S ++ + NS D
Sbjct: 1070 SDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD- 1128
Query: 770 TSPNGNDTSSVSGWGDPKPALRWGDSKGSNCQGGWEDDSAATGMVKSNQWGNCKEEKAAW 829
S + +D+S S D + DS S+ D S ++ S+ N + +
Sbjct: 1129 -SSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1187
Query: 830 NDSQKNKQGWGDGQKSSQGWSVSASDNWGETSRNNHWGEANKKSSSGGSDSDRSVSGWNE 889
+ S D SS S +SD+ + ++ ++ SS SDS S +
Sbjct: 1188 DSS--------DSSDSSD--SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDS 1237
Query: 890 LGKTSSFTWGNNINPNNSSGWDESSKPTPSQGWGDPPKSNQSLGWGDSSKPVSSPDWN 947
+ S N+ + ++SS +S+ + + N + DS D N
Sbjct: 1238 SDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSN 1295
Score = 95.5 bits (236), Expect = 5e-19
Identities = 187/1013 (18%), Positives = 364/1013 (35%), Gaps = 69/1013 (6%)
Query: 179 TNQQPQNNGEVQNSKNQSDINHSTSGSHYENSQRGPVSSTSDSSTNCKNAVVSDLSEKEA 238
T++ +N+ + I + +H E S+R T +S T+ V +K
Sbjct: 322 TSKSEENSAGIPEDNGSQRIEDTQKLNHRE-SKRVENRITKESETHA----VGKSQDKGI 376
Query: 239 WPSAPGSDPELASECMDADSASSSESERNITIMASGN--TGGEKDGLRNSTGLGSQNKFV 296
P S ++ + + + ++ I+ GN T GE + N G G +++
Sbjct: 377 EIKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGE---VVNIEGPGQKSE-- 431
Query: 297 VGSSSNNVGHGSSTGPWGFSHGAI---ISTCQVSVDAPESKSESS-NNRMNAWGTVSSSS 352
N VGH S+TG S G + D P S ES+ N+ N+ +SSS
Sbjct: 432 ---PGNKVGH-SNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSS 487
Query: 353 NGGLNPSTLNSASNHGAWPVLENNGLALKGPVG--SGSSGINIQCSTIGQMPNNQSINSK 410
G + ++ S N NG KG S S+ + G N N K
Sbjct: 488 RGDASYNSDESKDN--------GNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDK 539
Query: 411 VSGGSTHGTWGSLQETCESEVSGTQKVSFSGQPQNITTEMTGPNNTTNFMTSSLPNSGSV 470
G ++ S+ S + S S + + + +++++ +S +S S
Sbjct: 540 SDSGKGKS---DSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSS 596
Query: 471 QNNELPSSNTGAWRVSTMNHPQMQAPSGMNGTSLSHLSNGESKSGGSYGTTWGAYGSNYS 530
++ S+ + + + + S S S+ +SKS S + + ++ S
Sbjct: 597 DSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDS 656
Query: 531 GDKCSGPNGQANGDTVNAT---LMQPGVNGPMGTNFQVNTNKGGGVWESGAANSQSTSWG 587
D + N + D+ +++ N ++ ++N S +++S S+
Sbjct: 657 SDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSS 716
Query: 588 SGNGANSGGSRRGWGTPAQNTGTNLPSVEWNKLPSNQHSNDSANGNGKTFTNGWKSTEEE 647
+ +NS S + + ++ + S + + ++ S+DS++ + + ++ + +
Sbjct: 717 DSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDS 776
Query: 648 DQGSATSQTNEQSSVWAKTGGTVESDGSTESTGRLEEKGTGESQSRDRRKIDQHTLLQSI 707
S +S +N+ S+ SD S S + S S D D S
Sbjct: 777 SDSSNSSDSNDSSN---------SSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSS 827
Query: 708 VNRTDLDPRVLSNSGWGQTPIKQNTAWDTETSPRGERKTDNGTEAWGSSATQTFNSGACI 767
+ D SNS + D+++S R + + + S+ + +S +
Sbjct: 828 NSSDSSDS---SNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSD 884
Query: 768 DKTSPNGNDTSSVSGWGDPKPALRWGDSKGSNCQGGWEDDSAATGMVKSNQWGNCKEEKA 827
S N +D+S DS S+ + +++ SN + + +
Sbjct: 885 SNESSNSSDSS---------------DSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNS 929
Query: 828 AWNDSQKNKQGWGDGQKSSQGWSVSASDNWGETSRNNHWGEANKKSSSGGSDSDRSVSGW 887
+ N + + D SS + S S N ++S ++ ++N SS S+S S
Sbjct: 930 SDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSS 989
Query: 888 NELGKTSSFTWGNNINPNNSSGWDESSKPTPSQGWGDPPKSNQSLGWGDSSKPVSSPDWN 947
+ + S N+ + ++SS +SS + S D S+ S DSS S D +
Sbjct: 990 DSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSS 1049
Query: 948 KQQDIVGSWGIPPATGKPPGTGWLGGPIPAPAKEEEPTGWEEPSPESIRRKMEIDDGTSA 1007
D S ++ + + + E + S +S D S+
Sbjct: 1050 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSS 1109
Query: 1008 WGDPSKYNYKNVNMWNKNVPNGNSRSDQQAQVHQLLTPASAISNKEASSGSGWGEPWGEP 1067
S + + N + + + +S S + + +S S+ SS S +
Sbjct: 1110 DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD-SSDSSESSDSSDSSDSSDSSDSSDS 1168
Query: 1068 STPATTVDNGTSAWGKPIDSGPSWGEPIAAASSTSTWGSSSVGPQALSKSGPKSMQDGWC 1127
S + + D+ S+ DS S ++ SS S+ S S S S S
Sbjct: 1169 SDSSDSSDSSNSS-----DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1223
Query: 1128 GDDMPLPGNRPTGWEEEEDVEIGMWNSNSSQELNSSLNWPPYTKKMSSKGLSG 1180
N + + D +S+SS +SS + + S+ SG
Sbjct: 1224 DSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSG 1276
Score = 57.8 bits (138), Expect = 1e-07
Identities = 157/839 (18%), Positives = 271/839 (32%), Gaps = 78/839 (9%)
Query: 535 SGPNGQANGDTVNATLMQPGVN---------GPMGTNFQVNTNKGGGVWESGAANSQSTS 585
S NG + +T N + G N GP +T+ + E+ N +TS
Sbjct: 152 SNTNGNTDKNTQNGDVGDAGHNEDVAVVQEDGPQVAGSNNSTDNEDEIIENSCRNEGNTS 211
Query: 586 WGSGN-GANSGGSRRGWGTPAQNTGTNL------PSVEWNKLPSNQHSNDSAN---GNGK 635
+ + G++ TP L PS ++ S D + GNGK
Sbjct: 212 EITPQINSKRNGTKEAEVTPGTGEDAGLDNSDGSPSGNGADEDEDEGSGDDEDEEAGNGK 271
Query: 636 TFTNGWKSTE------EEDQGSATSQTNEQSSVW---AKTGGTVESDGSTESTGRLEEKG 686
+N K E E+D S+ Q ++ + K E DG + T + EE
Sbjct: 272 DSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKEYYDPEGKEDPHNEVDG--DKTSKSEENS 329
Query: 687 TGESQSRDRRKID-----QHTLLQSIVNRTDLDPR---VLSNSGWG---QTPIKQNTAWD 735
G + ++I+ H + + NR + V + G + P N
Sbjct: 330 AGIPEDNGSQRIEDTQKLNHRESKRVENRITKESETHAVGKSQDKGIEIKGPSSGNRNIT 389
Query: 736 TETSPRGERKTDNGTEAWGSSATQTFNSGACIDKTSP-------------NGNDTSSVSG 782
E E K D G G ++ P N S+ G
Sbjct: 390 KEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSEPGNKVGHSNTGSDSNSDG 449
Query: 783 WG--DPKPALRWGDSKGSNCQGGWEDDSAATGMVKSNQWGNCKEEKAAWNDSQKNKQGWG 840
+ D GD S+ + DD+ + S+ G+ A++N + G G
Sbjct: 450 YDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGD-----ASYNSDESKDNGNG 504
Query: 841 DGQKSSQ---GWSVSASDNWGETSRNNHWGEANKKSSSGGSDSDRSVSGWNELGK---TS 894
K ++ S S ++N N+ + N KS SG SD S S ++ +S
Sbjct: 505 SDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSS 564
Query: 895 SFTWGNNINPNNSSGWDESSKPTPSQGWGDPPKSNQSLGWGDSSKPVSSPDWNKQQDIVG 954
+ ++ + N+SS D S + D S+ S DSS S D + D
Sbjct: 565 DSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKS 624
Query: 955 SWGIPPATGKPPGTGWLGGPIPAPAKEEEPTGWEEPSPESIRRKMEIDDGTSAWGDPSKY 1014
++ + + + S +S D S+ S
Sbjct: 625 D-----SSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSS 679
Query: 1015 NYKNVNMWNKNVPNGNSRSDQQAQVHQLLTPASAISNKEASSGSGWGEPWGEPSTPATTV 1074
+ + N + + + +S S + + + S S+ SS S + S+ ++
Sbjct: 680 SSDSSNSSDSSDSSDSSNSSESSDSSD--SSDSDSSDSSDSSNSNSSDSDSSNSSDSSDS 737
Query: 1075 DNGTSAWGKPIDSGPSWGEPIAAASSTSTWGSSSVGPQALSKSGPKSMQDGWCGDDMPLP 1134
N + + S S + +S++S SS + S D D
Sbjct: 738 SNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDS 797
Query: 1135 GNRPTGWEEEEDVEIGMWNSNSSQELNSSLNWPPYTKKMSSKGLSGKKRRRERGMMKGGN 1194
N + + + + S + S N + +S S + N
Sbjct: 798 SNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSN 857
Query: 1195 KQEEAWINPF--VKQFSNISFSRDSPEENVQSNKMDLSGGMLQDKRMEIDKHSLNIGDYN 1252
+ + + + SN S S DS + N SN D S D S N D +
Sbjct: 858 RSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSD--SSNSSDSS 915
Query: 1253 RTVGKGPGSRPQISKESSMERNPYFDKDGIVADESQNMQFMSSQSMKLPPSNSALPNQA 1311
+ S S ++S + D + +S N S+ S S+S+ N +
Sbjct: 916 DSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSS 974
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 91.7 bits (226), Expect = 7e-18
Identities = 186/838 (22%), Positives = 303/838 (36%), Gaps = 130/838 (15%)
Query: 171 SQSESSALTNQQPQNNGEVQN-SKNQSDINHSTSGSHY-----ENSQRGPVSSTSDSSTN 224
S S S+ +Q +G+ + ++ S + HS+S + +S RGP S S S+
Sbjct: 1694 SGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSS- 1752
Query: 225 CKNAVVSDLSEKEAWPSAPGSDPELASECMDADSASSSESERNITIMASGNTGGEKDGLR 284
V E + S+ S S + S S ++ T G++ G+
Sbjct: 1753 -----VFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSS-H 1806
Query: 285 NSTGLGSQNKFVVGSSSNNVGHGSSTGPWGFSHGAIISTCQVSVDAPESKSESSNNRMNA 344
G GS G + G S G G G S S + +
Sbjct: 1807 GQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSG-------------HSSSYGQHGSGSG 1853
Query: 345 WGTVSSSSNGGLNPSTLNSASNHGAWPVLENNGLALKGPVGSGSSGINIQCSTIGQMPNN 404
W + S G S+ +W +++G G SS S GQ
Sbjct: 1854 WSSSSGRHGSGSGQSSGFGHHESSSW---QSSGYTQHGSGSGHSSSYEQHGSRSGQSSRG 1910
Query: 405 QSINSKVSGGSTHGTWGSLQETCESEVSGTQKVSFSGQPQNITTEMTGPNNTTNFMTSSL 464
+ S S++G GS + Q S SGQ + + G + + + +SS
Sbjct: 1911 EQHGSSSGSSSSYGQHGS---GSRQSLGHGQHGSGSGQSPSPSR---GRHGSGSGQSSSY 1964
Query: 465 P--NSGSVQNNELPSSNTGAWRVSTMNHPQMQAPS----GMNGTSLSHLS--------NG 510
SGS ++ +G+ S + H + ++ G +G+S H S +G
Sbjct: 1965 GPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASG 2024
Query: 511 ESKSGGSYGTTWG---AYGSNYSGDKCSGPNGQ---------ANGDTVNATLMQP--GVN 556
+S S G +G + G ++G + SG S G+ +G + + P G +
Sbjct: 2025 QSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRH 2084
Query: 557 GPMGTNFQVNTNKGGGVWESG------AANSQSTSW---GSGNGANSG----GSRRGWGT 603
G + G G+ ES +++ QS+S+ GSG+G +SG GSR G +
Sbjct: 2085 GSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSS 2144
Query: 604 PAQNTGTNLPSVEWNKLPSNQHSNDSANGNGKTFTNGWKSTEEEDQGSATSQTNEQSSVW 663
+ G++ S S +G+G ++G QGS + + +
Sbjct: 2145 RGERHGSS----------SGSSSRYGQHGSGSRQSSG-----HGRQGSGSGHSPSRGRHG 2189
Query: 664 AKTGGTVESDGSTESTGRLEEKGTGESQSRDRRKIDQHTL---LQSIVNRTDLDPRVLSN 720
+ +G + +GR +G ES+S QH S ++ +
Sbjct: 2190 SGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCS 2249
Query: 721 SGWGQTPIKQNTAWDTETSPRGERKTDNGTEAWGSSATQTFNSGACIDKTSPNGNDTSSV 780
G + Q++ +D E S G+ + +G GSS + ++ SP+ S
Sbjct: 2250 QGQHGSTSGQSSTFDQEGSSTGQ-SSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSG 2308
Query: 781 SGWGDPKPALRWGDSKGSNCQG-GWEDDSAATGMVKSNQWGNCKEEKAAWNDSQKNKQGW 839
SG S G + G GW S G G E ++W S + G
Sbjct: 2309 SGHSS---------SYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGS 2359
Query: 840 GDGQKSSQGWSVSASDNWGETSRNNHWGEANKKSSS---GGSDSDRSV------SGWNEL 890
G G SS S S G++SR G ++ SSS GS S +S+ SG +
Sbjct: 2360 GSGHSSSYEQHGSRS---GQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQS 2416
Query: 891 GKTSSFTWGNNINPNNS-------SGWDESSKPTP-----SQGWGD-PPKSNQSLGWG 935
S G+ ++S SGW S P S G G +S QS G+G
Sbjct: 2417 PSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYG 2474
Score = 91.3 bits (225), Expect = 8e-18
Identities = 154/716 (21%), Positives = 266/716 (37%), Gaps = 76/716 (10%)
Query: 260 SSSESERNITIMASGNTGGEKDGLRNSTGLG---SQNKFVVGSSSNNVGHGSSTGPWGFS 316
SSS+ + T + ++G R S+ G S ++ G ++ G G S G
Sbjct: 371 SSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPG----- 425
Query: 317 HGAIISTCQVSVDAPESKSESSNNRMNAWGTVSSSSNGGLNPSTLNSASNHGAWPVLENN 376
HG + +S SS +G SSSS ++ S +S H ++
Sbjct: 426 HG--------QRGSGSGQSPSSGQHGTGFGR-SSSSGPYVSGSGYSSGFGHHESSSEHSS 476
Query: 377 GLALKGPVGSGSSGINIQCSTIGQMPNNQSINSKVSGGSTHGTWGSLQETCESEVSGTQK 436
G G SSG S GQ + S S++G GS + ++
Sbjct: 477 GYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGS---GSRQSLGHSRH 533
Query: 437 VSFSGQPQNITTEMTGPNNTTNFMTSSLPNSGSVQNNELPSSNTGAWRVSTMNHPQMQAP 496
S SGQ + P+ + SGS Q++ G+ R S+ + P
Sbjct: 534 GSGSGQSPS-------PSRGRH-------ESGSRQSSSYGPHGYGSGRSSS------RGP 573
Query: 497 SGMNGTSLSHLSNGESKSGGSYGTTWGAYGSNYSGDKCSGPNGQANGDTVN-----ATLM 551
S L + ES+SG S G +G +GS+ G +G +G + + AT
Sbjct: 574 YESGSGHSSGLGHQESRSGQSSG--YGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSG 631
Query: 552 QPGVNGPMGTNFQVNT---NKGGGVWESGAANSQSTSWGSGNGANSGGSRRGWGTPAQNT 608
Q +G G+ ++ +G G +S + + +G + GS GW +
Sbjct: 632 QSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPH 691
Query: 609 G--TNLPSVEWNKLPSNQHSNDSANGNGKTFTNGWKSTEEEDQGSATSQTNEQSSVWAKT 666
G + S +K S Q S S +G+G + ++G++ S+ S+ + SS + +
Sbjct: 692 GSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSS 751
Query: 667 GGTVESDGSTESTGRLEEKGTGESQSRDRRKIDQHTLLQSIVNRTDLDPRVLSNSGWGQT 726
G GS +S+G +G+G S R + + S + S+ G ++
Sbjct: 752 YGQ-HGSGSHQSSGH-GRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYES 809
Query: 727 PIKQNTAWDTETSPRGERKTDNGTEAWGSSATQTFNSGACIDKTSPNGNDTSS--VSGWG 784
Q + + S G+ + +G+ A G ++Q + +S +D+SS S +G
Sbjct: 810 GSGQASGFGQHESGSGQGYSQHGS-ASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYG 868
Query: 785 DPKPALRWGDSKGSNCQGGWED---DSAATGMVKSNQWGNCKEEKAAWNDSQKNKQGWGD 841
+ A +G + G + +G +S +G + + S + G G
Sbjct: 869 QHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYG--RHGSGSGRSSSSGRHGSGS 926
Query: 842 GQKSSQGWSVSASDNWGETSRNNHWGEANKKSSSGGSDSDRSVSGWNELGKTSSFTWGNN 901
GQ S G S+ + G T + G ++ G S S + SS ++G +
Sbjct: 927 GQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQH 986
Query: 902 INPNNSS------GWDESSKPTPSQGWGDPPKSNQS--------LGWGDSSKPVSS 943
+ + S G P+PS+G S GW S P S
Sbjct: 987 GSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYES 1042
Score = 90.5 bits (223), Expect = 1e-17
Identities = 175/825 (21%), Positives = 298/825 (36%), Gaps = 111/825 (13%)
Query: 174 ESSALTNQQPQNNGEVQNSKNQSDINHSTSGSHY-----ENSQRGPVSSTSDSSTNCKNA 228
+SS Q + ++ S + HS+S + +S RGP S S S+
Sbjct: 1228 QSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSS----- 1282
Query: 229 VVSDLSEKEAWPSAPGSDPELASECMDADSASSSESERNITIMASGNTGGEKDGLRNSTG 288
V E + S+ S S + S S ++ T G++ G+ +
Sbjct: 1283 -VFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGS 1341
Query: 289 LGSQNKFVVGSSSNNVGHGSSTGPWGFSHGAIISTCQVSVDAPESKSESSNNRMNAWGTV 348
SQ+ S G GS P HG+ + S S + + W +
Sbjct: 1342 GSSQS-----SGYGRHGAGSGQSPSRGRHGS---------GSGHSSSYGQHGSGSGWSSS 1387
Query: 349 SSSSNGGLNPSTLNSASNHGAWPVLENNGLALKGPVGSGSSGINIQCSTIGQMPNNQSIN 408
S G S+ +W +++G G SS S GQ +
Sbjct: 1388 SGRHGSGSGQSSGFGHHESSSW---QSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHG 1444
Query: 409 SKVSGGSTHGTWGSLQETCESEVSGTQKVSFSGQPQNITTEMTGPNNTTNFMTSSLPNSG 468
S S++G GS + Q S SGQ + + G + + S SG
Sbjct: 1445 SSSGSSSSYGQHGS---GSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPY-GSG 1500
Query: 469 SVQNNELPSSNTGAWRVSTMNHPQMQAPS----GMNGTSLSHLS--------NGESKSGG 516
S ++ +G+ S + H + ++ G +G+S H S +G+S S G
Sbjct: 1501 SGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCG 1560
Query: 517 SYGTTWG---AYGSNYSGDKCSGPNGQ---------ANGDTVNATLMQP--GVNGPMGTN 562
+G + G ++G + SG S G+ +G + + P G +G
Sbjct: 1561 QHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGR 1620
Query: 563 FQVNTNKGGGVWESG------AANSQSTSW---GSGNGANSG----GSRRGWGTPAQNTG 609
+ G G+ ES +++ QS+S+ GSG+G +SG GSR G + + G
Sbjct: 1621 SSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHG 1680
Query: 610 TNLPSVEWNKLPSNQHSNDSANGNGKTFTNGWKSTEEEDQGSATSQTNEQSSVWAKTGGT 669
++ S S +G+G ++G QGS + Q+ + + G +
Sbjct: 1681 SS----------SRSSSRYGQHGSGSRQSSG-----HGRQGSGSGQSPSRGRHGSGLGHS 1725
Query: 670 VESDGSTESTGRLEEKGTGESQSRDRRKIDQH---TLLQSIVNRTDLDPRVLSNSGWGQT 726
+GR +G ES+S QH + S ++ + G +
Sbjct: 1726 SSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGS 1785
Query: 727 PIKQNTAWDTETSPRGERKTDNGTEAWGSSATQTFNSGACIDKTSP----NGNDTSSVSG 782
Q++ +D E S G+ + +G GSS + ++ SP +G+ + S
Sbjct: 1786 TSGQSSTFDQEGSSTGQ-SSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSS 1844
Query: 783 WGDPKPALRWGDSKGSNCQGGWEDDSAATGMVKSNQW---GNCKEEKAAWNDSQKNKQGW 839
+G W S G + G S+ G +S+ W G + + + S + G
Sbjct: 1845 YGQHGSGSGWSSSSGRH--GSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGS 1902
Query: 840 GDGQKS---SQGWSVSASDNWGETSRNNHWGEANKKSSSGGSDSDRSVSGWNELGKTSSF 896
GQ S G S +S ++G+ + + + SG S G + G S
Sbjct: 1903 RSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSS 1962
Query: 897 TWGNNINPNNSSGWDESSKPTP-----SQGWGD-PPKSNQSLGWG 935
++G + SGW S P S G G +S QS G+G
Sbjct: 1963 SYGPY---GSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYG 2004
Score = 90.1 bits (222), Expect = 2e-17
Identities = 214/917 (23%), Positives = 334/917 (36%), Gaps = 175/917 (19%)
Query: 171 SQSESSALTNQQPQNNGEVQN-SKNQSDINHSTS-GSHYE----NSQRGPVSSTSDSSTN 224
S S S+ QQ +G+ + ++ SD HS+S G H +S GP S S S+
Sbjct: 641 SGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSG 700
Query: 225 CKNAVVSDLSEKEAWPSAPGSDPELASECMDADSASSSESERNITIMA-SGNTGGEKDGL 283
+ S S + + GS + S SS SE++ + S + G G
Sbjct: 701 FGHKSGSGQSSGYSQHGS-GSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGS 759
Query: 284 RNSTGLGSQNKFVVGSSSNNVGHGSSTGPWGFSHGAIIS--TCQVSVDAPESKSE----- 336
S+G G Q G S + V HGSS+G SHG S +C S ES S
Sbjct: 760 HQSSGHGRQGSGS-GHSPSRVRHGSSSGH-SSSHGQHGSGTSCSSSCGHYESGSGQASGF 817
Query: 337 ---------------SSNNRMNAWG----TVSSSSNGGLNPSTLNSASNHGAWPVLENNG 377
S++ ++ G T SS+ G + S+ +S++G ++
Sbjct: 818 GQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHA 877
Query: 378 LALKGPVGSGSS---GINIQCSTIGQMPNNQSINSKVSGGSTHGTWGSLQETCESEVSGT 434
+G GSGS G + S GQ P+ S S+ G GS + SG
Sbjct: 878 SG-RGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGS----GSGQSSGF 932
Query: 435 QKVSFSGQPQNITTEMTGPNNTTNF--------MTSSLPNSGSVQNNELPSSNTGAWRVS 486
S SGQ T +G +++++ +S GS + G+
Sbjct: 933 GHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQ 992
Query: 487 TMNHPQMQAPSGMN------------GTSLSH-------------------------LSN 509
++ H Q + SG + G S S+ L +
Sbjct: 993 SLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGH 1052
Query: 510 GESKSGGSYGTTWGAYGSNYSGDKCSGPNGQANGDTVN-----ATLMQPGVNGPMGTNFQ 564
ES+SG S G +G +GS+ G +G +G + + A+ Q +G G+
Sbjct: 1053 RESRSGQSSG--YGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSS 1110
Query: 565 VNTNKGG---------GVWESGAANSQSTSWG---SGNGANSGGSRRGWGTPAQNTGTNL 612
++ G G + G+ + QS S+G SG+G +S + G G + +
Sbjct: 1111 QSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHH 1170
Query: 613 PSVEWNKLPSNQHSNDS--ANGNGKTFTNGWKSTEEEDQGSATSQTNE---------QSS 661
S +QH + S ++G G+ + +S+ E GS++ ++ QSS
Sbjct: 1171 ESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSS 1230
Query: 662 VWAKTG----------------GTVESDGSTES-TGRLEEKGTGESQSRDRRKIDQHTL- 703
+ G G S G S +GR +G ES+S QH
Sbjct: 1231 GHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESG 1290
Query: 704 --LQSIVNRTDLDPRVLSNSGWGQTPIKQNTAWDTETSPRGERKTDNGTEAWGSSATQTF 761
S ++ + G + Q++ +D E S G+ + G GSS + +
Sbjct: 1291 SGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQ-SSSYGHRGSGSSQSSGY 1349
Query: 762 NSGACIDKTSPNGNDTSSVSGWGDPKPALRWGDSKGSNCQG-GWEDDSAATGMVKSNQWG 820
SP+ S SG S G + G GW S G G
Sbjct: 1350 GRHGAGSGQSPSRGRHGSGSGHSS---------SYGQHGSGSGWSSSSGRHGSGSGQSSG 1400
Query: 821 NCKEEKAAWNDSQKNKQGWGDGQKSSQGWSVSASDNWGETSRNNHWGEANKKSSS---GG 877
E ++W S + G G G SS S S G++SR G ++ SSS G
Sbjct: 1401 FGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRS---GQSSRGERHGSSSGSSSSYGQHG 1457
Query: 878 SDSDRSV------SGWNELGKTSSFTWGNNINPNNS-------SGWDESSKP-----TPS 919
S S +S+ SG + S G+ ++S SGW S P + S
Sbjct: 1458 SGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHS 1517
Query: 920 QGWGD-PPKSNQSLGWG 935
G G +S QS G+G
Sbjct: 1518 SGLGHRESRSGQSSGYG 1534
Score = 89.0 bits (219), Expect = 4e-17
Identities = 193/853 (22%), Positives = 303/853 (35%), Gaps = 126/853 (14%)
Query: 147 QLLKRGQHFPVIAANLGSAVKVLNSQSESSALTNQQPQNNGEVQNSKNQSDINHSTSGSH 206
Q GQH GS +S + + + Q P S + S SGS
Sbjct: 1802 QSSSHGQH--------GSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSG 1853
Query: 207 YENSQRGPVSSTSDSSTNCKNAVVSDLSEKEAWPSAPGSDPELASECMDADSASSSESER 266
+ +S G S S S+ + S GS + E + S SS E+
Sbjct: 1854 WSSSS-GRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQ 1912
Query: 267 NITIMASGNTGGEK-DGLRNSTGLGSQNKFVVGSSSNNVG-HGS------STGPWGFSHG 318
+ + S ++ G+ G R S G G S S + G HGS S GP+G G
Sbjct: 1913 HGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSG 1972
Query: 319 AIISTCQVSVDAPESKS----ESSNNRMNAWGTVSSSSNGGLNPSTLNSASN-------H 367
S + S ES + + + +G SSS SAS H
Sbjct: 1973 WSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQH 2032
Query: 368 GAWPVLENNGLALKGPVGSGSS---GINIQCSTIGQMPNNQSINSKVSGGSTHGTWGSLQ 424
GA + + G GSGSS G Q S GQ P + S ++G GS
Sbjct: 2033 GA----SSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGS 2088
Query: 425 ETCES---------EVSGT-QKVSFSGQPQNITTEMTGPNNTTNFMTSSLPNSGSVQNNE 474
S E SG S SGQ + + +G +++ + + S +
Sbjct: 2089 GRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGER 2148
Query: 475 LPSSNTGAWRVSTMNHPQMQAPS-GMNGTSLSHL-SNGESKSGGSYGTTWGAYGSNYSGD 532
SS+ + R Q+ G G+ H S G SG + ++ G +GS
Sbjct: 2149 HGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRS 2208
Query: 533 KCSGPNGQANGDTV---------------------NATLMQPGVNGPMGTNFQVNTNKGG 571
GP +G + + G +G +G
Sbjct: 2209 SSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGS 2268
Query: 572 GVWES------GAANSQSTSWG---SGNGANSGGSRRGWGTPAQNT-GTNLPSVEWNKLP 621
+S G+ +SQS+S+G SG+G + R G G+ ++ G + W+
Sbjct: 2269 STGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSS-S 2327
Query: 622 SNQHSNDS--ANGNGKTFTNGWKSTEEEDQGSATSQTNEQSSVWAKTGGTVESDGSTEST 679
S +H + S ++G G ++ W+S+ GS + ++ +++G + + S+
Sbjct: 2328 SGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSS 2387
Query: 680 GRLEEKGTGESQSRDRRKIDQHTLLQSIVNRTDLDPRVLSNSGWGQTPIKQNTAWDTETS 739
G G S SR QH SG GQ+P S
Sbjct: 2388 GSSSSYGQHGSGSRQSLGHGQH------------------GSGSGQSP-----------S 2418
Query: 740 PRGERKTDNGTEAWGSSATQTFNSGACIDKT-SPNGNDTSSVSGWGDPKPALRWGDSKGS 798
P R +G+ + SS+ + SG+ + P + + SG G + R G S G
Sbjct: 2419 PSRGR---HGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRES--RSGQSSGY 2473
Query: 799 NCQGGWEDDSAATGM--VKSNQWGNCKEEKAAWNDSQKNKQGWGDGQKSSQGWSVSASDN 856
G S+ G S Q +C + A+ S + Q G G S G+ S +
Sbjct: 2474 GQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQH-GSGSSQSSGYGRQGSGS 2532
Query: 857 WGETSRNNHWGEANKKSSS---GGSDSDRSVSGWNE---LGKTSSFTWGNNINPNNSSGW 910
G++ + G +++S S GS S RS S LG++S F + + +SS
Sbjct: 2533 -GQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYS 2591
Query: 911 DESSKPTPSQGWG 923
S S G+G
Sbjct: 2592 QHGSGSGHSSGYG 2604
Score = 85.5 bits (210), Expect = 5e-16
Identities = 168/735 (22%), Positives = 270/735 (36%), Gaps = 105/735 (14%)
Query: 192 SKNQSDINHSTSGSHYENSQRGPVSSTSDSSTNCKNAVVSDLSEKEAWPSAPGSDPELAS 251
S + S + H S S + SS+ SST+ ++ S S A
Sbjct: 578 SGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGA--------- 628
Query: 252 ECMDADSASSSESERNITIMASGNTGGEKDGLRNSTGLGSQNKFVVGSSSNNVGHGSSTG 311
SSS + S G + G S G G SS+ HGS +G
Sbjct: 629 ----TSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGS-DFGHSSSYGQHGSGSG 683
Query: 312 PWGFSHGAIISTCQVSVDAPESKSESSNNRMNAWGTVSSSSNG----GLNPSTLNSASNH 367
W S+G S S ++ + G+ SS S+G G + + H
Sbjct: 684 -WSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQH 742
Query: 368 GAWPVLENNGLALK-GPVGSG---SSGINIQCSTIGQMPNNQSINSKVSGGSTHGTWG-- 421
G+ ++GL+ G GSG SSG Q S G P+ S S+HG G
Sbjct: 743 GS-----SSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSG 797
Query: 422 -SLQETCESEVSGTQKVSFSGQPQNITTEMTGPNNTTNFMTSSLPNSGSVQNNELPSSNT 480
S +C SG+ + S GQ ++ + + + + + SS GS SS++
Sbjct: 798 TSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQ---SSSS 854
Query: 481 GAWRVSTMNHPQMQAPSGMNG--TSLSHLSNGESKSGGSYGTT--WGAYGSNYSGDKCSG 536
G H S G S SH ++G + G G + G GS G
Sbjct: 855 G-------QHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYG 907
Query: 537 PNGQANGDTVNATLMQPGVNGPMGTNFQVNTNKGGGVWESGAANSQSTSW---GSGNGAN 593
+G +G + ++ G G + ++ + G + G+ + S+S+ GS +G +
Sbjct: 908 RHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQS 967
Query: 594 SGGSRRGWGTPAQNTGTNLPSVEWNKLPSNQHSNDSANGNGKTFTNGWKSTEEEDQGSAT 653
S + G + + ++ S L QH +G+G++ S GS +
Sbjct: 968 SRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQH----GSGSGQS-----PSPSRGRHGSGS 1018
Query: 654 SQTN-----EQSSVWAKTGGTVESDGSTESTGRLEEKGTGESQSRDRRKIDQHTLLQSIV 708
Q++ S W+ + G ES GS S+G G ES+S QH
Sbjct: 1019 GQSSSYGPYRSGSGWSSSRGPYES-GSGHSSG----LGHRESRSGQSSGYGQHG------ 1067
Query: 709 NRTDLDPRVLSNSGWGQTPIKQNTAWDTETSPRGERKTDNGTEA----WGSSATQTFNSG 764
S+SG T Q+ + ++S G+ +G + GS ++Q+ G
Sbjct: 1068 ----------SSSGHSSTH-GQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYG 1116
Query: 765 ACIDKTSPNGNDTSSVSGWGDPKPALRWGDSKGSNCQGGWEDDSA---ATGMVKSNQWGN 821
G+ + G G R S G + G S+ +G+ +S+ +G+
Sbjct: 1117 R-------QGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGH 1169
Query: 822 CKEEKAAWNDSQKNKQGWGDGQKSSQGWSVSASDNWGETSRNNHWGEANKKSSSGG--SD 879
E ++ S ++ G G G S G S S G++SR G ++ SS G
Sbjct: 1170 --HESSSGQSSSYSQHGSGSGHSSGYGQHGSRS---GQSSRGERHGSSSGSSSHYGQHGS 1224
Query: 880 SDRSVSGWNELGKTS 894
R SG G S
Sbjct: 1225 GSRQSSGHGRQGSGS 1239
Score = 65.1 bits (157), Expect = 7e-10
Identities = 143/706 (20%), Positives = 245/706 (34%), Gaps = 99/706 (14%)
Query: 163 GSAVKVLNSQSESSALTNQQPQNNGEVQNSKNQSDINHSTSGSHYENSQRGPVSSTSDSS 222
GS + + + + P S + S SGS +S RGP S S S
Sbjct: 2163 GSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSG-RSSSRGPYESRSGHS 2221
Query: 223 TNCKNAVVSDLSEKEAWPSAPGSDPELASECMDADSASSSESERNITIMASGNTGGEKDG 282
+ V E + S+ S S + S S ++ T G++ G+
Sbjct: 2222 S------VFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSS 2275
Query: 283 LRNSTGLGSQNKFVVGSSSNNVGHGSSTGPWGFSHGAIISTCQVSVDAPESKSESSNNRM 342
G GS G + G S G G G S S +
Sbjct: 2276 -HGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSG-------------HSSSYGQHGSG 2321
Query: 343 NAWGTVSSSSNGGLNPSTLNSASNHGAWPVLENNGLALKGPVGSGSSGINIQCSTIGQMP 402
+ W + S G S+ +W +++G G SS S GQ
Sbjct: 2322 SGWSSSSGRHGSGSGQSSGFGHHESSSW---QSSGYTQHGSGSGHSSSYEQHGSRSGQSS 2378
Query: 403 NNQSINSKVSGGSTHGTWGSLQETCESEVSGTQKVSFSGQPQNITTEMTGPNNTTNFMTS 462
+ S S++G GS + Q S SGQ + + G + + S
Sbjct: 2379 RGERHGSSSGSSSSYGQHGS---GSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYS 2435
Query: 463 SLPNSGSVQNNELPSSNTGAWRVSTMNHPQMQAPS----GMNGTSLSHLS--------NG 510
SGS ++ +G+ S + H + ++ G +G+S H S +G
Sbjct: 2436 PY-GSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSG 2494
Query: 511 ESKSGGSYGTTWG---AYGSNYSGDKCSGPNGQ---------ANGDTVNATLMQP--GVN 556
+S S G +G + G ++G + SG S G+ +G + + P G +
Sbjct: 2495 QSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRH 2554
Query: 557 GPMGTNFQVNTNKGGGVWESG------AANSQSTSW---GSGNGANSG----GSRRGWGT 603
G + G G+ ES +++ QS+S+ GSG+G +SG GSR G +
Sbjct: 2555 GSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSS 2614
Query: 604 PAQNTGTNLPSVEWNKLPSNQHSNDSANGNGKTFTNGWKSTEEEDQGSATSQTNEQSSVW 663
+ G++ S S+ +G+G ++G QGS + Q+ +
Sbjct: 2615 RGERHGSS----------SGSSSHYGQHGSGSRQSSG-----HGRQGSGSGQSPSRGRHG 2659
Query: 664 AKTGGTVESDGSTESTGRLEEKGTGESQSRDRRKIDQH---TLLQSIVNRTDLDPRVLSN 720
+ G + +GR +G ES+ QH + S ++ +
Sbjct: 2660 SGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCS 2719
Query: 721 SGWGQTPIKQNTAWDTETSPRGERKT----------DNGTEAWGSSATQTFNSGACIDKT 770
G + Q++ +D E S G+ + +G G+ + Q+ + G +
Sbjct: 2720 QGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGS 2779
Query: 771 SPNGNDTSSVSGWGDPKPALRWGDSKG----SNCQGGWEDDSAATG 812
+ + SG G + G G S C+GG D ++G
Sbjct: 2780 GQSSSYGQHGSGSGQSSGYSQHGSGSGQDGYSYCKGGSNHDGGSSG 2825
Score = 63.9 bits (154), Expect = 1e-09
Identities = 135/614 (21%), Positives = 246/614 (40%), Gaps = 67/614 (10%)
Query: 363 SASNHGAWPVLENNGLA--LKGPVGSGSSGINIQCSTIGQMPNNQSINSKVSGGSTHGTW 420
S+ +H +W EN+ + ++G + G+ I+ + S Q + NS S++G
Sbjct: 125 SSFSHSSWSAGENDSYSRNVRGSLKPGTESISRRLSF--QRDFSGQHNSYSGQSSSYGEQ 182
Query: 421 GSLQETCESEVSGTQKVSFSGQPQNITTEMTGPNNTTNFMTSSLPNSGSVQNNELPSSNT 480
S ++ +S G Q S SGQ N +G +++ T SGS Q++ +
Sbjct: 183 NS--DSHQSSGRG-QCGSGSGQSPNYGQHGSGSGQSSSNDTHG---SGSGQSSGFSQHKS 236
Query: 481 GAWRVSTMNHPQMQAPSGMNGTSLSHLS-NGESKSGGSYGTTWGA---YGSNYSGDKCS- 535
+ + S + Q + SG + H S +G+S G + ++ G+ YG + SG + S
Sbjct: 237 SSGQSS--GYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSL 294
Query: 536 GPNGQANGDTVNATLMQPGV-------NGPMGTNFQVNTNKGGGVWESGAANSQSTSWG- 587
G Q +G + + ++ G +G G+ + ++G +ESG+ Q++ +G
Sbjct: 295 GHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGH--YESGSG--QTSGFGQ 350
Query: 588 --SGNGANSGGSRRGWGTPAQNTGTNLPSVEWNKLPSNQHSNDS---------------A 630
SG+G +SG S+ G G+ ++ S S QH + S +
Sbjct: 351 HESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHS 410
Query: 631 NGNGKTFTNGWKSTEEEDQGSATSQTNEQSSVWAKTGGTVESDGSTESTGRLEEKGTGES 690
+G G+ + +S +GS + Q+ G + S +G G ES
Sbjct: 411 SGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHES 470
Query: 691 QSRDRRKIDQHTLLQSIVNRTDLDPRVLSNSGWGQTPIKQNTAWDTETS----PRGERKT 746
S QH S + + S SG +Q ++ + +S G R++
Sbjct: 471 SSEHSSGYTQH---GSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQS 527
Query: 747 DNGTEAWGSSATQTFNSGACIDKTSPNGNDTSSVSGWGDPKPALRWGDSKGSNCQGGWED 806
G GS + Q+ + ++ + + G+G + + R GS G
Sbjct: 528 -LGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGH 586
Query: 807 DSAATGMVKSNQWGNCKEEKAAWNDSQKNKQGWGDGQKSSQGWSVSASDNWGETSRNNHW 866
+ +G +S+ +G + ++ + S + G GQ SS G + S G++S +
Sbjct: 587 QESRSG--QSSGYG--QHGSSSGHSSTHGQHGSTSGQSSSCGQHGATS---GQSSSHGQH 639
Query: 867 GEANKKSSSGGSDSDRSVSGWNELGKTSSFTWGNNINPNNS-SGWDESSKP-----TPSQ 920
G + +SS G S + S F ++ + S SGW S+ P S
Sbjct: 640 GSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSS 699
Query: 921 GWGDPPKSNQSLGW 934
G+G S QS G+
Sbjct: 700 GFGHKSGSGQSSGY 713
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 78.2 bits (191), Expect = 7e-14
Identities = 191/989 (19%), Positives = 349/989 (35%), Gaps = 140/989 (14%)
Query: 62 SVSQPQPANSNNGTSTATSTNNNA--KRATANNQQPQQQQQQQQPQQQQPQQQPQPQPQQ 119
S SQ +S + +A+ ++ + ++ ++ P+ Q+ + Q +
Sbjct: 2571 SDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRH 2630
Query: 120 QQPQQQPQALPRYP--REVPPRFRHQEHKQLLKRGQHFPVIAANLGSAVKVLNSQSESSA 177
Q QA + R H+Q +H + SAV+ + S +
Sbjct: 2631 TQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGS 2690
Query: 178 LTNQQPQNNGEVQNSKNQSDINHSTSGSH---YENSQRGPVSSTSDSSTNCKNAV----V 230
Q N G ++S QS H +GSH ++ S RG TS S + V
Sbjct: 2691 ---QASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQ 2747
Query: 231 SDLSEKEAWPSAPGSDPELASECMDADSASSSESERNI-------------------TIM 271
S+ S PS G + D+ S+S+ ++ ++
Sbjct: 2748 SESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVD 2807
Query: 272 ASGNTG---------GEKDGLRNSTGLGS-----QNKFVVGSSSNNVG---HGSST---- 310
+SG++G G D R +G S +N+ G S + G H +ST
Sbjct: 2808 SSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADI 2867
Query: 311 -----GPWGFSHGAIISTCQVSVDAPESKSESSNNRMNAWGTVSSSSNGGLNPSTLNSAS 365
G S G+ S Q S + +S SE + W +S ++ G L S
Sbjct: 2868 SRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGS 2927
Query: 366 NHGAWPVLENNGLALKGPVGSGSSGINIQCSTIGQMPNN-----------------QSIN 408
H + G S + Q S+ GQ ++ QS +
Sbjct: 2928 RHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSAD 2987
Query: 409 SKVSGGSTHGTWGS-LQETCESEVSGTQKVSFSGQPQNITTEMTGPNNTTNFMTSSLPNS 467
S G HG S ++++ SG+Q G ++ T+ + S S
Sbjct: 2988 SSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQES 3047
Query: 468 GSVQNNELPSSNTGAWRVSTMNHPQMQAPSGMNGTSL-SHLSNGESKSGGSYGTTWGAYG 526
++ E S ++G++ H Q ++ G G S + ++ S + YG
Sbjct: 3048 ARGRSGE-TSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQYG 3106
Query: 527 SN----YSGDKCSGPNGQANGDTVNATLMQPGVNGPMGTNFQVNTNKGGGVWESGAANSQ 582
+ + G G G + +V++ +G G++ T++G G + S+
Sbjct: 3107 QDTIRGHPGSSRGGRQGYHHEHSVDS-------SGHSGSHHSHTTSQGRSDASRGQSGSR 3159
Query: 583 STSWGSGNGANSGGSRRGWGTPAQNTGTNLPSVEWNKLPSNQ-HSNDSANGNGKTFTNGW 641
S S + N SG S R + T+ ++ Q + + G + +
Sbjct: 3160 SASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDS 3219
Query: 642 KS---TEEEDQGSATSQTNEQSSVWAKTGGTVESDGSTESTGRLEEK-GTGESQSRDRRK 697
S +E+ ++ S ++ N + SV ++ GS E++ G G S R R+
Sbjct: 3220 DSEGHSEDSERWSGSASRNHRGSVQEQS-----RHGSRHPRSHHEDRAGHGHSADRSRQS 3274
Query: 698 IDQHTLLQSIVNRTDLDPRVLSNSGWGQTPIKQNTAWDTETS--PRGERKTD-NGTEAWG 754
+H S + S+ G Q +A + S PRG+ + + WG
Sbjct: 3275 GTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWG 3334
Query: 755 SSATQTFNSGACIDKTSPNGNDTSSVSGWGDPKPALRWGDSKGSNCQGG----------- 803
SS +Q +S ++ +DT SVSG G P + + GG
Sbjct: 3335 SSGSQASDSEGHSEE-----SDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQ 3389
Query: 804 ---WEDDSAATGMVKSN---QWGNCKEEKAAWNDSQKNKQGW-------GDGQKSSQG-- 848
E +A G +++ + G+ E+ + +++G G ++ QG
Sbjct: 3390 VSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSH 3449
Query: 849 WSVSASDNWGETSRNNHWGEANKKSSSGGSDSDRSVS----GWNELGKTSSFTWGNNINP 904
+ S + S ++H + +S G RS S + G S +W ++
Sbjct: 3450 YEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHEA 3509
Query: 905 NNSSGWDESSKPTPSQGWGDPPKSNQSLG 933
+ + D S QG P+++++ G
Sbjct: 3510 STQA--DSSRHSQSGQGQSAGPRTSRNQG 3536
Score = 64.3 bits (155), Expect = 1e-09
Identities = 157/785 (20%), Positives = 284/785 (36%), Gaps = 97/785 (12%)
Query: 192 SKNQSDINHSTSGSHYENSQRGPVSSTSDSSTNC-----KNAVVSDLSE-----KEAWPS 241
S+ +SD +H SGS + Q + D S + + A +D S +E
Sbjct: 1200 SQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSG 1259
Query: 242 APGSDPELASECMDADSASSSESERNITIMASGNTGG-----EKDGLRNSTGLGSQNKFV 296
+ S + +S D+DS S+ ++ AS N G +DG R+ G +++
Sbjct: 1260 SRTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRH-PGFHQEDRAS 1318
Query: 297 VGSSSNNVGHGSSTGPWGFSHGAIISTCQVSVDAPESKSESSNNRMNAWGTVSSSSNGGL 356
G S+++ + SHG +S+ + + +P + S + + + SS + G+
Sbjct: 1319 HGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQ-----SADSSRHSGI 1373
Query: 357 NPSTLNSA---SNHGAWPVLENNGLALKGPVGSGSSGINIQCSTIGQMPNNQSINSKVSG 413
+SA S H ++G + G S GQ +Q + + +
Sbjct: 1374 GHRQASSAVRDSGHRG-----SSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESAR 1428
Query: 414 GSTHGTWGSLQETCESEVSGTQKVSFSGQPQNITTEMTGPNN--TTNFMTSSLPNSGSVQ 471
G + + G + S Q S GQ T G + N S G
Sbjct: 1429 GQSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDT 1488
Query: 472 NNELPSSNTGAWRVSTMNHPQMQAPSGMNGTSLSHLSNGESKSGGSYGTTWGAYGSNYS- 530
P S+ G + S H Q SG +G SH + + +S S+G + S +
Sbjct: 1489 IRGHPGSSRGGRQGS--YHEQSVDRSGHSGYHHSH-TTPQGRSDASHGQSGPRSASRQTR 1545
Query: 531 GDKCSGPNGQANGDTVNATLMQPGVNGPMGTNFQVNTNKGGGVWESGAANSQSTSWGSGN 590
++ SG + +G + +P + QV + G S S +
Sbjct: 1546 NEEQSGDGSRHSGSRHH----EPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSE 1601
Query: 591 GANSGGSRRGWGTPAQNTGTNLPSVEWNKLPSNQHSNDSANGNGKTFTNGWKSTEEEDQG 650
G + RR + G+ H D A+ ++ T +
Sbjct: 1602 GHSEDSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETS 1661
Query: 651 S----ATSQTNEQSSVWAKTGGTVE--SDGSTES-TGRLEE---------KGTGESQSRD 694
S A+SQ +SS + G + +D ST+S TGR ++ +G+ SQ+ D
Sbjct: 1662 SGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASD 1721
Query: 695 RRKIDQHTLLQSIVNRTDLDPRVLSNSGWGQTPIKQNTAWDTETSPRGERKTDNGTEAWG 754
+ + QS+ S GQ Q + ++ GER +G+ +
Sbjct: 1722 SEGHSEESDTQSV-------------SAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQ 1768
Query: 755 SSATQTFNSGACIDKTSPN-----------GNDTSSVSGWGDPKPALRW--GDSKGSNCQ 801
S + S + +T P+ D+S S + + +R G S+G
Sbjct: 1769 VSTHE--QSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQG 1826
Query: 802 GGWEDDSAATGMVKSNQWGNCKEEKAAWNDSQ----------KNKQGWGDGQKSSQGWSV 851
+E ++G S+ +E++ + Q +N++ GDG + S
Sbjct: 1827 SHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHH 1886
Query: 852 SASDNWGETSRNNHWGEANKKSSSGGSDSDRSVSGWNELGKTS--SFTWGNNINPNN-SS 908
AS ++SR++ G+ + SVS ++ S S W + + N+ S
Sbjct: 1887 EASSR-ADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGS 1945
Query: 909 GWDES 913
W++S
Sbjct: 1946 AWEQS 1950
Score = 59.7 bits (143), Expect = 3e-08
Identities = 171/873 (19%), Positives = 300/873 (34%), Gaps = 125/873 (14%)
Query: 71 SNNGTSTATSTNNNAKRATANNQQPQQQQQQQQPQQQQPQQQPQPQPQQQQPQQQPQALP 130
S +G T +++ + Q + PQ + Q P++
Sbjct: 1482 SQDGQDTIRGHPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSAS 1541
Query: 131 RYPREVPPRFRHQEHKQLLKRGQHFPVIAANLGSAVKVLNSQSESSALTNQQPQNNGEVQ 190
R R H H P A +V +S S + +Q + + +
Sbjct: 1542 RQTRNEEQSGDGSRHSG---SRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDR 1598
Query: 191 NSKNQSDINHSTSGSHYENSQRGPVSSTSDSSTNCKNAVVSDLSEKEAWPSAPGSDPELA 250
+S+ S+ + S S N + S N ++ S + S+ S A
Sbjct: 1599 DSEGHSEDSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHA 1658
Query: 251 SECMDADSASSSESERNITIMASGNTGGEKDGLRNSTGLG-SQNKFVVGSSSNNVGHGSS 309
+ASS E R+ G+ + +G G Q+ VVG S N GSS
Sbjct: 1659 ETSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGN---RGSS 1715
Query: 310 TGPWGFSHGAIISTCQVSVDAPESKSESSNNRMNAWGTVSSSSNGGLNPSTLNSASNHG- 368
G+ +S S G S S S HG
Sbjct: 1716 ------------------------------------GSQASDSEGHSEESDTQSVSAHGQ 1739
Query: 369 AWPVLENNGLALKGPVG--SGSSGINIQCSTIGQMPNNQSINSKVSGGSTHGTWGSLQET 426
A P +++ + +G G SG SG S + Q+ ++ S+ + G T + G Q +
Sbjct: 1740 AGPHQQSHQESTRGQSGERSGRSG-----SFLYQVSTHE--QSESAHGRTGPSTGGRQRS 1792
Query: 427 CESEVSGTQKVSFSGQPQNITTEMTGPNNTTNFMTSSLPNSGSVQNNELPSS-NTGAWRV 485
+ + + S S + Q+ G +S GS + SS ++G+
Sbjct: 1793 RHEQARDSSRHSASQEGQDTIRGHPG--------SSRGGRQGSHYEQSVDSSGHSGSHHS 1844
Query: 486 STMNHPQMQAPSGMNGT-SLSHLSNGESKSGGSYGTTWGAYGSNYSGDKCSGPNGQANGD 544
T + + G +G+ S+S + E +SG GS +SG + + +A+
Sbjct: 1845 HTTSQERSDVSRGQSGSRSVSRQTRNEKQSGD---------GSRHSGSRHHEASSRADSS 1895
Query: 545 TVNATLMQPGVNGPMGTNFQVNTNKGGGV---WESGAANSQSTSWGSGNGANSGGSRRGW 601
++ + Q +GP + + N+G V +S + S W N GS W
Sbjct: 1896 R-HSQVGQGQSSGP-----RTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGS--AW 1947
Query: 602 GTPAQNTGTNLPSVEWNKLPSNQHSNDSANGNGKTFTNGWKSTEEEDQGSATSQTNEQSS 661
G+ P + HS DS+ +G + TE +G A S + S
Sbjct: 1948 --EQSRDGSRHPGSHHEDRAGHGHSADSSR------QSGTRHTESSSRGQAASSHEQARS 1999
Query: 662 VWAKTGGTVESDGSTESTGRLEEKGTGESQSRDRRKIDQHTLLQSIVNRTDLDPRVLSNS 721
+ G+ S +S+ G G Q+ + H R + +
Sbjct: 2000 SAGERHGSHHQLQSADSS---RHSGIGHGQASSAVRDSGH--------RGYSGSQASDSE 2048
Query: 722 GWGQTPIKQNTAWDTETSPRGERKTDNGTEAWGSSATQTFNSGACIDKTSPNGNDTSSVS 781
G + Q+ + + P + ++ A G S + SG+ + + S + + S
Sbjct: 2049 GHSEDSDTQSVSAQGKAGPHQQSHKES---ARGQSGESSGRSGSFLYQVSTH-EQSESTH 2104
Query: 782 GWGDPKPALRWG--------DSKGSNCQGGWEDDSAATGMVKSNQWGNCKEEK------A 827
G P R G S+ S Q G + G + + G+ +E+ +
Sbjct: 2105 GQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQSVDRSGHS 2164
Query: 828 AWNDSQKNKQGWGD---GQKSSQGWSVSASDNWGETSRNNHWGEANKKSSSGGSDSDRSV 884
+ S QG D GQ S+ S D + H G + ++SS S S+
Sbjct: 2165 GSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSL 2224
Query: 885 SGWNE-LGKTSSFTWGNNIN-PNNSSGWDESSK 915
G + G +S G++++ ++S G E S+
Sbjct: 2225 VGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSE 2257
Score = 59.3 bits (142), Expect = 4e-08
Identities = 150/762 (19%), Positives = 262/762 (34%), Gaps = 108/762 (14%)
Query: 175 SSALTNQQPQNNGEVQNSKNQSDINHSTSGSHYENSQRGPVSSTSDSSTNCKNAVVSDLS 234
SS + + G+ Q+S ++ N +S S +SQ S S + +N + S
Sbjct: 1889 SSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWE 1948
Query: 235 EKEAWPSAPGSDPE-LASECMDADSASSSESERNITIMASGNTGGEKDGLRNSTGL--GS 291
+ PGS E A ADS+ S + R+ + G + R+S G GS
Sbjct: 1949 QSRDGSRHPGSHHEDRAGHGHSADSSRQSGT-RHTESSSRGQAASSHEQARSSAGERHGS 2007
Query: 292 QNKFVVGSSSNNVGHGSSTGPWGFSHGAIISTCQVSVDAPESKSESSNNRMNAWGTVSSS 351
++ SS + G G HG S + S S S++S+
Sbjct: 2008 HHQLQSADSSRHSGIG---------HGQASSAVRDSGHRGYSGSQASD------------ 2046
Query: 352 SNGGLNPSTLNSASNHG-AWPVLENNGLALKGPVG--SGSSGINI-QCSTIGQMPNNQSI 407
S G S S S G A P +++ + +G G SG SG + Q ST Q +
Sbjct: 2047 SEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQVSTHEQSESTHGQ 2106
Query: 408 NSKVSGGSTHGTWGSLQETCESEVSGTQKVSFSGQPQNITTEMTGPNNTTNFMTSSLPNS 467
++ +GG + Q++ S + + G P GP+
Sbjct: 2107 SAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHP--------GPSRGGR--------Q 2150
Query: 468 GSVQNNELP-SSNTGAWRVSTMNHPQMQAPSGMNGTSLSHLSNGESKSGGSYGTTWGAYG 526
GS Q + S ++G+ T + + A G +G+ S S +Y G
Sbjct: 2151 GSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGS--------RSASRKTYDKEQSGDG 2202
Query: 527 SNYSG----DKCSGPNGQANGDTVNATLMQPGVNGPMGTNFQVNTNKGGGVWESG--AAN 580
S +SG + S + + P + P G++ +++ G +S + +
Sbjct: 2203 SRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGS 2262
Query: 581 SQSTSWGSGNGANSGGSRRGWGTPAQNTGTNLPSVEWNKLPSNQHSNDSANGNGKTFTNG 640
+ GS + GSR G S E ++ H+ +S+ G +
Sbjct: 2263 ASRNHHGSAQEQSRDGSRHPRSHHEDRAGHG-HSAESSRQSGTHHAENSSGGQAASSHEQ 2321
Query: 641 WKSTEEEDQGSATSQTNEQSSV----WAKTGGTVESDGSTESTGRLEEKGTGESQSRDRR 696
+S+ E GS Q+ + S + V G S+G G S+ D +
Sbjct: 2322 ARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQ 2381
Query: 697 KIDQHTLL--QSIVNRTDLDPRVLSNSGWGQTPIKQNTAWDTETSPRGERKTDNG----- 749
+ H ++ R SG + + Q + + S G T G
Sbjct: 2382 SVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGS 2441
Query: 750 --TEAWGSSATQTFNSGA---------------------CIDKTSPNGNDTSSVSGWGDP 786
+A SS T G +D++ +G+ S + G
Sbjct: 2442 HHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRS 2501
Query: 787 KPALRWGDSKGSNCQGGWEDDSAATGMVKSNQWGNCKEEKAAWNDSQKNKQGWGDGQKSS 846
+ S+ ++ Q D+ + G S + +A + + QG +G ++S
Sbjct: 2502 DASHGHSGSRSASRQTR-NDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTS 2560
Query: 847 QGWSVSAS------------DNWGETSRNNHWGEANKKSSSG 876
+ W S S + W ++ NH G A ++ G
Sbjct: 2561 RNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDG 2602
Score = 56.2 bits (134), Expect = 3e-07
Identities = 179/929 (19%), Positives = 321/929 (34%), Gaps = 123/929 (13%)
Query: 10 KDVERNLSRDLVQEEEQLMEEKKKKKDDKKKKEAAQKKATEQKIKVPEQIKPSVSQPQPA 69
K E +R E+ K K K +E K+ K + + +
Sbjct: 114 KQEENKENRKRPSSLERRNNRKGNKGRSKSPRETGGKRHESSSEKKERKGYSPTHREEEY 173
Query: 70 NSNNGTSTATSTNNNAKRATANNQQPQQQQQQQQPQQQQPQQQPQPQPQQQQPQQQPQAL 129
N+ S+ N +N++ ++ +++ ++ + + Q Q +
Sbjct: 174 GKNHHNSSKKEKNKTENTRLGDNRKRLSERLEEKEDNEEGVYDYENTGRMTQKWIQSGHI 233
Query: 130 PRYPREVPPRFRHQEHKQLLKRGQHFPVIAANLGSAVKVLNSQSESSALTNQQPQNNGEV 189
Y + + LL+ + + ++ G + +N + T+Q P
Sbjct: 234 ATYYTIQDEAYDTTD--SLLEENKIYERSRSSDGKSSSQVNRSRHEN--TSQVPLQESRT 289
Query: 190 QNSKNQSDINHSTSGSHYENSQRGPVSSTSDSSTNCKNAVVSDLSEKEAWPSAPGSDPEL 249
+ + S H E+S+R + +S N + + P + D +
Sbjct: 290 RKRRGSRVSQDRDSEGHSEDSER----HSGSASRNHHGSAWEQSRDGSRHPRS--HDEDR 343
Query: 250 ASECMDADSASSSESERNITIMASGNTGGEKDGLRNSTGLGSQNKFVVGSSSNNVGHGSS 309
AS ADS+ S + R+ + G T + R+S G HGS
Sbjct: 344 ASHGHSADSSRQSGT-RHAETSSRGQTASSHEQARSSPG---------------ERHGS- 386
Query: 310 TGPWGFSHGAIISTCQVSVDAPESKSESSNNRMNAWGTVSSSSNGGLNPSTLNSASNHG- 368
G A S + S + S + G+ +S S G S S S HG
Sbjct: 387 ----GHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGK 442
Query: 369 AWPVLENNGLALKGPVG--SGSSGINIQCSTIGQMPNNQSINSKVSGGSTHGTWGSLQET 426
A +++ + +G G SG SG ++ + + P++ + G ST G GS E
Sbjct: 443 AGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRT---GTSTGGRQGSHHE- 498
Query: 427 CESEVSGTQKVSFSGQPQNITTEMTGPNNTTNFMTSSLPNSGSVQNNELPSSNTGAWRVS 486
++ S S GQ + G ++ + SV S ++G+
Sbjct: 499 -QARDSSRHSASQEGQDT-----IRGHPGSSRGGRQGSHHEQSVNR----SGHSGSHHSH 548
Query: 487 TMNHPQMQAPSGMNGT-SLSHLSNGESKSGGSYGTTWGAYGSNYSGDKCSGPNGQANGDT 545
T + + A G +G+ S S + E +SG G+ +SG + + QA+
Sbjct: 549 TTSQGRSDASHGQSGSRSASRQTRNEEQSGD---------GTRHSGSRHHEASSQADSSR 599
Query: 546 VNATLMQPGVNGPMGTNFQVNTNKGGGVWE---SGAANSQSTSWGSGNGANSGGS----- 597
++ + Q +GP + + N+G V + S + S W N GS
Sbjct: 600 -HSQVGQGQSSGP-----RTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQS 653
Query: 598 RRGWGTPA---QNTGTNLPSVEWNKLPSNQHSNDSANGNGKTFTNGWKSTEEEDQGSATS 654
R G P ++ + S + ++ +H+ +S++G + +S+ E GS
Sbjct: 654 RDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQ 713
Query: 655 QTNEQSSVWAKTG-----GTVESDGSTESTGRLEEKGTGESQSRDRRKIDQH-------- 701
+ SS + TG V G S+G G S+ D + + H
Sbjct: 714 LQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQ 773
Query: 702 TLLQSIVNRTDLDPRVLSNSGWGQTPIKQNTAWDTETSP--------RGERKTDNGTEAW 753
+ +S +R+ R + + + KQ+ + T P E+ DN +
Sbjct: 774 SHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSA 833
Query: 754 GSSATQTFNSGACIDKTSPNGN------DTSSVSGWGDPKPALRWGDSKGSNCQGGWEDD 807
T + G+ D S SG G S S Q G
Sbjct: 834 SQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSG-SHHSHTTSQGRSDASRGQSGSRSA 892
Query: 808 SAATGMVK-----SNQWGNCKEEKAAWNDSQKNKQ---GWGDGQKSS--QGWSVSA---- 853
S T + S G+ E ++ D ++ Q G +G ++S QG SVS
Sbjct: 893 SRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDS 952
Query: 854 ------SDNWGETSRNNHWGEANKKSSSG 876
S+ W ++ NH G A ++S G
Sbjct: 953 EGHSEDSERWSGSASRNHRGSAQEQSRHG 981
Score = 53.9 bits (128), Expect = 2e-06
Identities = 160/812 (19%), Positives = 283/812 (34%), Gaps = 70/812 (8%)
Query: 160 ANLGSAVKVLNSQSESSALTNQQPQNNGEVQNSKNQSDINHSTSGSHYENSQRGPVSSTS 219
A++ + + QSE S + +Q + + +S+ S+ + SGS N
Sbjct: 2865 ADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLR 2924
Query: 220 DSSTNCKNAVVSDLSEKEAWPSAPGSDPELASECMDADSASSSESERNITIMASGNTGGE 279
D S + ++ + S+ S +ASS E R+ G+ +
Sbjct: 2925 DGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQ 2984
Query: 280 KDGLRNSTGLGSQNKFVVGSSSNNVGHGSSTGPWGFSHGAIISTCQVSVDAPESKSESSN 339
+G+G S + G+ S H T VS ++ S +
Sbjct: 2985 SADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHG-QAGSHQQS 3043
Query: 340 NRMNAWGTVSSSSNGGLNPSTLNSASNHGAWPVLENNGLALKGPVGSGSSGI-NIQCSTI 398
++ +A G S G + S L S H + GP G G + Q
Sbjct: 3044 HQESARGR--SGETSGHSGSFLYQVSTHEQ----SESSHGWTGPSTRGRQGSRHEQAQDS 3097
Query: 399 GQMPNNQSINSKVSG--GSTHGTWGSLQETCESEVSGTQKVSFSGQPQNITTEMTGPNNT 456
+ +Q + G GS+ G + SG SG + TT G ++
Sbjct: 3098 SRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSG-----HSGSHHSHTTSQ-GRSDA 3151
Query: 457 TNFMTSSLPNSGSVQNNELPSSNTGAWRVSTMNHPQMQAPSGMNGTSLSHLSNGESKS-- 514
+ + S S + +N E S ++ VS + A + ++ S G +S
Sbjct: 3152 SRGQSGSRSASRTTRNEE-QSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRR 3210
Query: 515 -GGSYGTTWGAYGSNYSGDKCSGPNGQANGDTVNATLMQPGVNGPMGTNFQVNTNKGGGV 573
G S + G + ++ SG + + +V + G P ++ + G
Sbjct: 3211 QGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQ-SRHGSRHPR-SHHEDRAGHGHSA 3268
Query: 574 WESGAANSQSTSWGSGNGANSGGSRRGWGTPAQNTGT----NLPSVEWNKLPSNQHSN-- 627
S + ++ SG A S + +P + G+ + S + +P Q S+
Sbjct: 3269 DRSRQSGTRHAETSSGGQAASS-HEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAV 3327
Query: 628 -DSAN--GNGKTFTNGWKSTEEEDQGSATS-------QTNEQSSVWAKTGGTVESDGS-- 675
DS + +G ++ +EE D S + Q + Q S ++GG GS
Sbjct: 3328 RDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFL 3387
Query: 676 -TESTGRLEEKGTGESQSRDRRKIDQHTLLQSIVNRTDLDPRVLSNSGWGQTPIKQNTAW 734
ST E G +++ R+ H + D S S GQ I+ +
Sbjct: 3388 YQVSTHEQSESAHGRTRTSTGRRQGSH-------HEQARDSSRHSASQEGQDTIRGH--- 3437
Query: 735 DTETSPRGERKTDNGTEAWGSSATQTFNSGACIDKTSPNGNDTSS--VSGWGDPKPALRW 792
P R+ G+ + S ++ +SG+ T+ G +S SG R
Sbjct: 3438 -----PGSSRRGRQGSH-YEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRN 3491
Query: 793 GDSKGSNCQGGWEDDSAATGMVKSNQWGNCKEEKAAWNDSQKNKQGWGDGQKSSQGWSVS 852
+ G + W A+ S++ + ++A + +N+ SQG S
Sbjct: 3492 DEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSED 3551
Query: 853 ASDNWGETSRNNHWGEANKKSSSG-----GSDSDRSVSGWNELGKTSSFTWGNNINPNNS 907
S+ W ++ NH G A ++S G DR+ G + SS G + N+S
Sbjct: 3552 -SERWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHS---AESSRQSGTHHAENSS 3607
Query: 908 SGWDESSKPTPSQGWGDPPKSNQSLGWGDSSK 939
G SS G+ S+ DSS+
Sbjct: 3608 GGQAASSHEQARSSAGERHGSHHQQS-ADSSR 3638
Score = 49.3 bits (116), Expect = 4e-05
Identities = 154/791 (19%), Positives = 278/791 (35%), Gaps = 119/791 (15%)
Query: 152 GQHFPVIAANLGSAVKVLNSQSESSALTNQQPQNNGEVQNSKNQ--SDINHSTSGSHYEN 209
G H ++ S+ L Q +SS +P+ + Q+S ++ S+ + SGS N
Sbjct: 2207 GSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRN 2266
Query: 210 SQRGPVSSTSDSSTNCKNAVVSDLSEKEAWPSAPGSDPELASECMDADSASSSESERNIT 269
+ D S + ++ + S+ S A +ASS E R
Sbjct: 2267 HHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQAR--- 2323
Query: 270 IMASGNTGGEKDGLRNSTGLGSQNKFVVGSSSNNVGHGSSTGPWGFSHGAIISTCQVSVD 329
++ GE+ G + S S + +GHG +
Sbjct: 2324 -----SSAGERHGSHHQQSADS-------SRHSGIGHGQA-------------------- 2351
Query: 330 APESKSESSNNRMNAWGTVSSSSNGGLNPSTLNSASNHG-AWPVLENNGLALKGPVG--S 386
S + + + G+ +S S G S S S HG A P +++ + +G S
Sbjct: 2352 ---SSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRS 2408
Query: 387 GSSGINIQCSTIGQMPNNQSINSKVSGGSTHGTWGSLQETCESEVSGTQKVSFSGQPQNI 446
G SG S + Q+ ++ S+ + G T + G Q + + + + S S + Q+
Sbjct: 2409 GRSG-----SFLYQVSTHE--QSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDT 2461
Query: 447 TTEMTGPNNTTNFMTSSLPNSGSVQNNELP-SSNTGAWRVSTMNHPQMQAPSGMNGT-SL 504
G +SS GS + S ++G+ T + + A G +G+ S
Sbjct: 2462 IHGHPG--------SSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSA 2513
Query: 505 SHLSNGESKSGGSYGTTWGAYGSNYSGDKCSGPNGQANGDTVNATLMQPGVNGPMGTNFQ 564
S + + +SG GS +SG + + +A+ + ++ + Q GP
Sbjct: 2514 SRQTRNDEQSGD---------GSRHSGSRHHEASSRAD-SSGHSQVGQGQSEGP------ 2557
Query: 565 VNTNKGGGVWESGAANSQSTSWGSGNGANSGG-SRRGWGTPAQNTGTNLPSVEWNKLPSN 623
T++ G S ++SQ S S + S + G G+ P +
Sbjct: 2558 -RTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGH 2616
Query: 624 QHSNDSANGNGKTFTNGWKSTEEEDQGSATSQTNEQSSVWAKTGGTVESDGSTESTGRLE 683
HS DS+ +G T + G + ++EQ+ + G +S
Sbjct: 2617 GHSADSSRQSGTRHT-------QTSSGGQAASSHEQA---RSSAGERHGSHHQQSADSSR 2666
Query: 684 EKGTGESQSRDRRKIDQHTLLQSIVNRTDLDPRVLSNSGWGQTPIKQNTAWDTETSPRGE 743
G G Q+ + H R + N G + Q+ + + G
Sbjct: 2667 HSGIGHGQASSAVRDSGH--------RGYSGSQASDNEGHSEDSDTQSVSAHGQA---GS 2715
Query: 744 RKTDNGTEAWGSSATQTFNSGACIDKTSPNGNDTSSVSGWGDPKPALRWG--------DS 795
+ + A G S + +SG+ + + S + SS GW P R G S
Sbjct: 2716 HQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESS-HGWTGPSTRGRQGSRHEQAQDSS 2774
Query: 796 KGSNCQGGWEDDSAATGMVKSNQWGNCKEEK------AAWNDSQKNKQGWGD---GQKSS 846
+ S Q G + G + + G E + + S QG D GQ S
Sbjct: 2775 RHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGS 2834
Query: 847 QGWSVSASDNWGETSRNNHWGEANKKSSSGG--SDSDRSVSGWNELGKTSSFTWGNNINP 904
+ S + + + H G + ++S+ S ++V G +E + S +
Sbjct: 2835 RSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQD 2894
Query: 905 NNSSGWDESSK 915
++S G E S+
Sbjct: 2895 SDSEGHSEDSE 2905
Score = 47.4 bits (111), Expect = 1e-04
Identities = 170/897 (18%), Positives = 298/897 (33%), Gaps = 110/897 (12%)
Query: 62 SVSQPQPANSNNGTSTATSTNNNAKRATANNQQPQQQQQQQQPQQQQPQQQPQPQPQQQQ 121
SVS A S+ + ++ + + + + Q +Q + P + +Q
Sbjct: 3030 SVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGS 3089
Query: 122 PQQQPQALPRYPREVPPRFRHQEHKQLLKRG------QHFPVIAANLGSAVKVLNSQSES 175
+Q Q R+ + + H + G +H + + GS SQ S
Sbjct: 3090 RHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRS 3149
Query: 176 SALTNQQPQNNGE--VQNSKNQSDINHSTSGSHYENSQRGPVSSTSDSSTNCKNAVVSDL 233
A Q + +N + D + + H+E S +S S + S
Sbjct: 3150 DASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEG--SRR 3207
Query: 234 SEKEAWPSAPGSDPELASECMDADSASSSESERNITIMASGN-----------TGGEKDG 282
S ++ + SD E SE + S S+S + R S + G
Sbjct: 3208 SRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHS 3267
Query: 283 LRNSTGLGSQNKFVVGSSSNNVGHGSSTGPWGFSHGAIISTCQVSVDA------PESKSE 336
S G+++ H + G HG S Q S D+ P ++
Sbjct: 3268 ADRSRQSGTRHAETSSGGQAASSHEQARSSPGERHG---SRHQQSADSSRHSGIPRGQAS 3324
Query: 337 SSNNRMNAWGTV---SSSSNGGLNPSTLNSASNHG-AWPVLENNGLALKGPVG--SGSSG 390
S+ WG+ +S S G S S S HG A P +++ + + G SG SG
Sbjct: 3325 SAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSG 3384
Query: 391 INIQCSTIGQMPNNQSINSKVSGGSTHGTWGSLQETCESEVSGTQKVSFSGQPQNITTEM 450
S + Q+ ++ S+ + G T + G Q + + + + S S + Q+
Sbjct: 3385 -----SFLYQVSTHEQ--SESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGH 3437
Query: 451 TGPNNTTNFMTSSLPNSGSVQNNELP-SSNTGAWRVSTMNHPQMQAPSGMNGT-SLSHLS 508
G +S GS + S ++G+ T + + A G +G+ S S +
Sbjct: 3438 PG--------SSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQT 3489
Query: 509 NGESKSGGSYGTTWGAYGSNYSGDKCSGPNGQANGDTVNATLMQPGVNGPMGTNFQVNTN 568
+ +SG +W + + S + G + P + G++ +++
Sbjct: 3490 RNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAG-----PRTSRNQGSSVSQDSD 3544
Query: 569 KGGGVWESG--AANSQSTSWGSGNGANSGGSRRGWGTPAQNTGTNLPSVEWNKLPSNQHS 626
G +S + ++ GS + GSR G S E ++ H+
Sbjct: 3545 SQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHG-HSAESSRQSGTHHA 3603
Query: 627 NDSANGNGKTFTNGWKSTEEEDQGSATSQTNEQSSV----WAKTGGTVESDGSTESTGRL 682
+S+ G + +S+ E GS Q+ + S + V G S+G
Sbjct: 3604 ENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQ 3663
Query: 683 EEKGTGESQSRDRRKIDQHTLL--QSIVNRTDLDPRVLSNSGWGQTPIKQNTAWDTETSP 740
G S+ D + + H ++ R SG + + Q + + S
Sbjct: 3664 ASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESA 3723
Query: 741 RGERKTDNG-------TEAWGSSATQTFNSGACIDKTSPNGN-------------DTSSV 780
G G +A SS G + P D S
Sbjct: 3724 HGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGH 3783
Query: 781 SGWGDPKPALRWGDSKGSNCQGGWEDDSAATGMVK-----SNQWGNCKEEKAAWNDSQKN 835
SG G S S+ Q G S T + S G+ E + DS ++
Sbjct: 3784 SG-SHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEASTQADSSRH 3842
Query: 836 KQGWGDGQKSS------QGWSVSA----------SDNWGETSRNNHWGEANKKSSSG 876
Q G G+ + QG SVS S+ E++ NH G + ++S G
Sbjct: 3843 SQS-GQGESAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQSRDG 3898
Score = 41.2 bits (95), Expect = 0.010
Identities = 85/380 (22%), Positives = 133/380 (35%), Gaps = 61/380 (16%)
Query: 614 SVEWNKLPSNQHSNDSANGNGKTFTNGWKSTEEEDQGSATSQTNEQSSVWAKTGG----T 669
S + ++ +H+ S+ G + +S+ E GS Q+ + S A G
Sbjct: 349 SADSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSA 408
Query: 670 VESDGSTESTGRLEEKGTGESQSRDRRKIDQHTL--LQSIVNRTDLDPRVLSNSGWGQTP 727
V G S+G G S++ D + + H L+ ++ R SG +
Sbjct: 409 VSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSS 468
Query: 728 IKQNTAWDTETSPRGERKTDNGTEAWGSSATQTFNSGACIDKTSPNGNDT---------- 777
+ Q + + S G T G GS Q +S S G DT
Sbjct: 469 LYQVSTHEQPDSAHGRTGTSTGGRQ-GSHHEQARDSSR--HSASQEGQDTIRGHPGSSRG 525
Query: 778 --------SSVSGWGDPKPALRWGDSKG-SNCQGGWEDDSAATGMVKSNQW--------G 820
SV+ G S+G S+ G +A+ ++ + G
Sbjct: 526 GRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSG 585
Query: 821 NCKEEKAAWNDSQKNKQGWGDGQKS------SQGWSVSA----------SDNWGETSRNN 864
+ E ++ DS ++ Q G GQ S +QG SVS S+ W ++ N
Sbjct: 586 SRHHEASSQADSSRHSQV-GQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRN 644
Query: 865 HWGEANKKSSSG-----GSDSDRSVSGWNELGKTSSFTWGNNINPNNSSGWDESSKPTPS 919
H G A ++S G DR+ G + SS G N+SSG SS
Sbjct: 645 HHGSAQEQSRDGSRHPRSHHEDRAGHGHS---ADSSRKSGTRHTQNSSSGQAASSHEQAR 701
Query: 920 QGWGDPPKSNQSLGWGDSSK 939
G+ S L DSS+
Sbjct: 702 SSAGERHGSRHQLQSADSSR 721
>gi|169173184 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1230
Score = 73.2 bits (178), Expect = 2e-12
Identities = 95/419 (22%), Positives = 155/419 (36%), Gaps = 62/419 (14%)
Query: 478 SNTGAWRVSTMNHPQMQAPSGMNGTSLSHLSNGESKSGGSYGTTWGAYGSNYSGDKCSGP 537
SN+G W + + + + SG S S S + S+ +W + S+ S
Sbjct: 32 SNSG-WASPSASGASIPSDSGWASPSASGASTPSNSGWASFSASWASIPSDSGWASPSAS 90
Query: 538 NGQANGDTVNATLMQPGVNGPMGTNFQVNTNKGGGV----WESGAANSQSTSWGSGNGAN 593
D+ A+ G + P + + + G + W S +A+ ST SG +
Sbjct: 91 WASTPSDSGWASPSASGASIPSDSGWASPSVSGASIPSAFWASPSASGASTPSDSGWASP 150
Query: 594 SGGSRRGWGTPAQNTGTNLPSVEWNKLPSNQHSNDSANGNGKTFTNGWKSTEEEDQGSAT 653
S W + + ++G PS W PS ++ SA+G +GW S +T
Sbjct: 151 SAS----WASTSSDSGWASPSASWTS-PSASCASSSASGASTPSDSGWASPSVFWVSPST 205
Query: 654 SQTNEQSSV-WAKTGGTVESDGSTESTGRLEEKGTGESQSRDRRKIDQHTLLQSIVNRTD 712
S + S WA T +S ++ S + +G S S D S V+ +
Sbjct: 206 SWASSPSDFGWASTPS--DSGWASSSASCISPSASGASTSSDSGWASPSA---SWVSTST 260
Query: 713 LDPRVLSNSGWGQTPIKQNTAWDTETSPRG----ERKTDNGTEAWGSSATQTFNSGACID 768
S+SGW + + +WD+ TS G + + +W S+ + + +S +
Sbjct: 261 SRASTSSDSGWASS----SASWDSITSDSGWVCPSASWASSSASWASAPSDSGSSSPSVS 316
Query: 769 KTSPNGNDTSSVSGWGDPKPALRWGDSKGSNCQGGWEDDSAATGMVKSNQWGNCKEEKAA 828
+ S T SVSGW + G S S+ GW SA+
Sbjct: 317 RAS-----TLSVSGWASFSAS---GASAPSD--SGWTSHSAS------------------ 348
Query: 829 WNDSQKNKQGWGDGQKSSQGWSVSASDNWGETSRNNHWGEANKKSSSGGSDSDRSVSGW 887
S + GW S+ G S S+ W S + W + +S SD SGW
Sbjct: 349 -GVSTTSDSGW--ASPSASGASTSSDSGWASPSAS--WASPSASGASTPSD-----SGW 397
Score = 73.2 bits (178), Expect = 2e-12
Identities = 106/414 (25%), Positives = 147/414 (35%), Gaps = 63/414 (15%)
Query: 719 SNSGWGQ-----TPIKQNTAWDTETSPRGERKTDNGTEAWGSSATQTFNSGACIDKTSPN 773
SNSGW I ++ W SP + W S + + + SP+
Sbjct: 32 SNSGWASPSASGASIPSDSGW---ASPSASGASTPSNSGWASFSASWASIPSDSGWASPS 88
Query: 774 GN--DTSSVSGWGDPKPALRWGDSKGSNCQGGWEDDSAATGMVKSNQWGNCKEEKAAWND 831
+ T S SGW P + G S S+ GW S + + S W + +A
Sbjct: 89 ASWASTPSDSGWASPSAS---GASIPSD--SGWASPSVSGASIPSAFWAS----PSASGA 139
Query: 832 SQKNKQGWGDGQKSSQGWSVSASDN-WGETSRNNHWGEANKKSSSGGSDSDRSVSGWNEL 890
S + GW S W+ ++SD+ W S + A+ SSS S S SGW
Sbjct: 140 STPSDSGWAS---PSASWASTSSDSGWASPSASWTSPSASCASSSASGASTPSDSGW--- 193
Query: 891 GKTSSFTWGNNINPNNSSGWDESSKPTPSQ-GWGDPPKSNQSLGWGDSSKPVSSPDWNKQ 949
+ S W ++P+ S W S PS GW P + GW SS SP +
Sbjct: 194 -ASPSVFW---VSPSTS--WASS----PSDFGWASTPSDS---GWASSSASCISPSASGA 240
Query: 950 QDIVGS-WGIPPATGKPPGTGWLGGPIPAPAKEEEPTGWEEPSPESIRRKMEIDDGTSAW 1008
S W P A+ T + A +GW S + S W
Sbjct: 241 STSSDSGWASPSASWVSTST--------SRASTSSDSGWASSSAS-----WDSITSDSGW 287
Query: 1009 GDPSKYNYKNVNMWNKNVPNGNSRSDQQAQVHQLLTPASA---ISNKEASSGSGWGEPWG 1065
PS + W + S S ++ L A S A S SGW
Sbjct: 288 VCPSASWASSSASWASAPSDSGSSSPSVSRASTLSVSGWASFSASGASAPSDSGWTSH-- 345
Query: 1066 EPSTPATTVDNGTSAWGKPIDSGPSWGEPIAAASSTSTWGS-SSVGPQALSKSG 1118
S +TT D+G W P SG S AS +++W S S+ G S SG
Sbjct: 346 SASGVSTTSDSG---WASPSASGASTSSDSGWASPSASWASPSASGASTPSDSG 396
Score = 69.7 bits (169), Expect = 3e-11
Identities = 106/447 (23%), Positives = 160/447 (35%), Gaps = 88/447 (19%)
Query: 576 SGAANSQSTSWGSGNGAN-SGGSRRGWGTPAQNTGTNLPSVEWNKLPSNQHSNDSANGNG 634
SG + + W S + + S S GW +P+ + G ++PS PS ++ +N
Sbjct: 10 SGVSTPSGSGWASSSASGASTPSNSGWASPSAS-GASIPSDSGWASPSASGASTPSNSGW 68
Query: 635 KTFTNGWKSTEEEDQGSATSQTNEQSSVWAKTGGTVESDGSTESTGRLEEKGTGESQSRD 694
+F+ W S D G A+ S+ WA T +G +G S D
Sbjct: 69 ASFSASWASIPS-DSGWASP-----SASWAST---------PSDSGWASPSASGASIPSD 113
Query: 695 RRKIDQHTLLQSIVNRTDLDPRVLSNSGWGQTPIKQNTAWDTETSPRGERKTDNGTEAWG 754
SI + P S SG TP ++ W + ++ +D+G W
Sbjct: 114 SGWASPSVSGASIPSAFWASP---SASG-ASTP--SDSGWASPSASWASTSSDSG---WA 164
Query: 755 S-SATQTFNSGACIDKTSPNGNDTSSVSGWGDPK-----PALRWGDSKGSNCQGGWEDDS 808
S SA+ T S +C +S +G T S SGW P P+ W S GW
Sbjct: 165 SPSASWTSPSASCAS-SSASGASTPSDSGWASPSVFWVSPSTSWASSPSDF---GWASTP 220
Query: 809 AATGMVKSNQWGNCKEEKAAWNDSQKNKQGWGDGQKSSQGWSVSASDNWGETSRNNHWGE 868
+ +G S+ +C A+ G S S+ W S + W
Sbjct: 221 SDSGWASSS--ASCISPSAS-------------------GASTSSDSGWASPSAS--WVS 257
Query: 869 ANKKSSSGGSDSDRSVSGWNELGKTSSFTWGNNINPNNSSGWDESSKPTPSQGWGDPPKS 928
+ +S SD SGW +SS +W + + SGW PS W S
Sbjct: 258 TSTSRASTSSD-----SGW----ASSSASWD---SITSDSGW-----VCPSASWA---SS 297
Query: 929 NQSLGWGDSSKPVSSPDWNKQQDI-VGSWGIPPATG--KPPGTGWLGGPIPAPAKEEEPT 985
+ S S SSP ++ + V W A+G P +GW + + +
Sbjct: 298 SASWASAPSDSGSSSPSVSRASTLSVSGWASFSASGASAPSDSGWTSHSASGVSTTSD-S 356
Query: 986 GWEEPSPESIRRKMEIDDGTSAWGDPS 1012
GW PS + S W PS
Sbjct: 357 GWASPSASGASTSSD-----SGWASPS 378
Score = 56.6 bits (135), Expect = 2e-07
Identities = 73/307 (23%), Positives = 101/307 (32%), Gaps = 80/307 (26%)
Query: 840 GDGQKSSQGWSVSASDNWGETSRNNHWGEANKKSSSGGSDSDRSVSGWNELGKTSSFTWG 899
G S GW+ S+S + T N+ W + +S SDS GW + + T
Sbjct: 11 GVSTPSGSGWA-SSSASGASTPSNSGWASPSASGASIPSDS-----GWASPSASGASTPS 64
Query: 900 NNINPNNSSGW----DESSKPTPSQGWGDPPKSNQSLGWGDSSKPVSSPDWNKQQDIVGS 955
N+ + S+ W +S +PS W P + GW S +S +
Sbjct: 65 NSGWASFSASWASIPSDSGWASPSASWASTPSDS---GWASPSASGASIPSDS------G 115
Query: 956 WGIPPATGKPPGTGWLGGPIPAPAKEEEPTGWEEPSPESIRRKMEIDDGTSAWGDPSKYN 1015
W P +G + + P + A +GW PS + S W PS
Sbjct: 116 WASPSVSGASIPSAFWASPSASGASTPSDSGWASPSASWASTSSD-----SGWASPSA-- 168
Query: 1016 YKNVNMWNKNVPNGNSRSDQQAQVHQLLTPASAISNKEASSGSGWGEP---WGEPSTP-- 1070
W P+ + S S+ S S SGW P W PST
Sbjct: 169 -----SWTS--PSASCAS-------------SSASGASTPSDSGWASPSVFWVSPSTSWA 208
Query: 1071 ---------ATTVDNG----------TSAWGKPIDSGPSWGEPIAAASSTST-------- 1103
+T D+G SA G S W P A+ STST
Sbjct: 209 SSPSDFGWASTPSDSGWASSSASCISPSASGASTSSDSGWASPSASWVSTSTSRASTSSD 268
Query: 1104 --WGSSS 1108
W SSS
Sbjct: 269 SGWASSS 275
Score = 45.8 bits (107), Expect = 4e-04
Identities = 85/418 (20%), Positives = 144/418 (34%), Gaps = 52/418 (12%)
Query: 429 SEVSGTQKVSFSGQPQNITTEMTGPNNT----TNFMTSSLPN-----SGSVQNNELPSSN 479
S SG S SG + + + P+N+ + +S+P+ S S PS++
Sbjct: 7 SRASGVSTPSGSGWASSSASGASTPSNSGWASPSASGASIPSDSGWASPSASGASTPSNS 66
Query: 480 TGAWRVSTMNHPQMQAPSGMNGTSLSHLSNGESKSGGSYGTTWGAYGSNYSGDKCSGPNG 539
W + + + + SG S S S S SG + + GA + SG +G
Sbjct: 67 --GWASFSASWASIPSDSGWASPSASWAST-PSDSGWASPSASGASIPSDSGWASPSVSG 123
Query: 540 QANGDTVNATLMQPGVNGPMGTNFQVNTNKGGGVWESGAANSQSTSWGSGNGANSGGSRR 599
+ A+ G + P + + + S S SW S + + + S
Sbjct: 124 ASIPSAFWASPSASGASTPSDSGWASPSASWASTSSDSGWASPSASWTSPSASCASSSAS 183
Query: 600 GWGTPAQNTGTN------LPSVEWNKLPSN-----------------QHSNDSANGNGKT 636
G TP+ + + PS W PS+ + SA+G +
Sbjct: 184 GASTPSDSGWASPSVFWVSPSTSWASSPSDFGWASTPSDSGWASSSASCISPSASGASTS 243
Query: 637 FTNGWKSTEEEDQGSATSQTNEQS-SVWAKTGGTVESDGSTESTGRLEEKGTGESQSRDR 695
+GW S ++TS+ + S S WA + + +S S S S
Sbjct: 244 SDSGWASPSASWVSTSTSRASTSSDSGWASSSASWDSITSDSGWVCPSASWASSSASWAS 303
Query: 696 RKIDQHTLLQSIVNRTDLDPRVLSNSGWGQ-----TPIKQNTAWDTETSPRGERKTDNGT 750
D + S+ + LS SGW ++ W + ++ +D+G
Sbjct: 304 APSDSGSSSPSVSRAS-----TLSVSGWASFSASGASAPSDSGWTSHSASGVSTTSDSGW 358
Query: 751 EAWGSSATQTFNSGACIDKT------SPNGNDTSSVSGWGDPKPALRWGDSKGSNCQG 802
+ +S T + + S +G T S SGW P + S S C G
Sbjct: 359 ASPSASGASTSSDSGWASPSASWASPSASGASTPSDSGWASPSASGASMPSAPSLCPG 416
Score = 38.9 bits (89), Expect = 0.050
Identities = 34/141 (24%), Positives = 53/141 (37%), Gaps = 26/141 (18%)
Query: 1654 DRNSGSSSSLNTTLPSTSAWSSIRASNYNVPLSS------------------TAQSTSAR 1695
D S S+ + PS S W+S AS ++P S + S S
Sbjct: 49 DSGWASPSASGASTPSNSGWASFSASWASIPSDSGWASPSASWASTPSDSGWASPSASGA 108
Query: 1696 NSDSKLTWSPGSVTNTSLAHELWKVPLPPKNITAPSRPPPGLTGQKPPLSTWDNSPLRIG 1755
+ S W+ SV+ S+ W P +A P +G P ++W ++
Sbjct: 109 SIPSDSGWASPSVSGASIPSAFWASP------SASGASTPSDSGWASPSASWAST--SSD 160
Query: 1756 GGWGNSDARYTPGSSWGESSS 1776
GW + A +T S+ SSS
Sbjct: 161 SGWASPSASWTSPSASCASSS 181
Score = 38.1 bits (87), Expect = 0.085
Identities = 48/225 (21%), Positives = 73/225 (32%), Gaps = 51/225 (22%)
Query: 956 WGIPPATGK--PPGTGWLGGPIPAPAKEEEPTGWEEPSPESIRRKMEIDDGTSAWGDPSK 1013
W A+G P +GW P + A +GW PS S PS
Sbjct: 20 WASSSASGASTPSNSGW-ASPSASGASIPSDSGWASPS-------------ASGASTPSN 65
Query: 1014 YNYKNVNMWNKNVPNGNSRSDQQAQVHQLLTPASAISNKEASSGSGWGEP---------- 1063
+ + + ++P+ + + A S S SGW P
Sbjct: 66 SGWASFSASWASIPSDSGWASPSA------------SWASTPSDSGWASPSASGASIPSD 113
Query: 1064 --WGEPSTPATTVDNGTSAWGKPIDSGPSWGEPIAAASSTSTWGSSSVGPQALSKSGPKS 1121
W PS ++ + + W P SG S AS +++W S+S S SG S
Sbjct: 114 SGWASPSVSGASIPS--AFWASPSASGASTPSDSGWASPSASWASTS------SDSGWAS 165
Query: 1122 MQDGWCGDDMPLPGNRPTGWEEEEDVEIGMWNSNSSQELNSSLNW 1166
W + +G D W S S ++ S +W
Sbjct: 166 PSASWTSPSASCASSSASGASTPSD---SGWASPSVFWVSPSTSW 207
Score = 35.8 bits (81), Expect = 0.42
Identities = 33/139 (23%), Positives = 53/139 (38%), Gaps = 22/139 (15%)
Query: 1659 SSSSLNTTLPSTSAWSSIRASNYNVPLSS--TAQSTSARNSDSKLTWSPGSVTNTSLAHE 1716
SSS+ + PS S W+S AS ++P S + S S ++ S W+ S + S+ +
Sbjct: 22 SSSASGASTPSNSGWASPSASGASIPSDSGWASPSASGASTPSNSGWASFSASWASIPSD 81
Query: 1717 --------LWKVPLPPKNITAPSR-----------PPPGLTGQKPPLSTWDNSPLRIGGG 1757
W +PS P ++G P + W SP G
Sbjct: 82 SGWASPSASWASTPSDSGWASPSASGASIPSDSGWASPSVSGASIPSAFW-ASPSASGAS 140
Query: 1758 WGNSDARYTPGSSWGESSS 1776
+ +P +SW +SS
Sbjct: 141 TPSDSGWASPSASWASTSS 159
Score = 35.4 bits (80), Expect = 0.55
Identities = 29/85 (34%), Positives = 35/85 (41%), Gaps = 5/85 (5%)
Query: 1047 SAISNKEASSGSGWGEPWGE-PSTPATTVDNGTSAWGKPIDSGPSWGEPIAAASST---S 1102
S S SGSGW STP+ + SA G I S W P A+ +ST S
Sbjct: 7 SRASGVSTPSGSGWASSSASGASTPSNSGWASPSASGASIPSDSGWASPSASGASTPSNS 66
Query: 1103 TWGSSSVGPQAL-SKSGPKSMQDGW 1126
W S S ++ S SG S W
Sbjct: 67 GWASFSASWASIPSDSGWASPSASW 91
Score = 33.9 bits (76), Expect = 1.6
Identities = 58/231 (25%), Positives = 90/231 (38%), Gaps = 19/231 (8%)
Query: 201 STSGSHYENSQRGPVSSTSDSSTNCKNAVVSD----LSEKEAWPSAPGSDPELASECMDA 256
S S S S SS S +ST + S +S +W S+P SD AS D+
Sbjct: 165 SPSASWTSPSASCASSSASGASTPSDSGWASPSVFWVSPSTSWASSP-SDFGWASTPSDS 223
Query: 257 DSASSSESERNITIMASGNTGGEKDGLRNSTGLGSQNKFVVGSSSNNVGHGSSTGPWG-- 314
ASSS S I+ ASG + G + + S+S++ G SS+ W
Sbjct: 224 GWASSSAS--CISPSASGASTSSDSGWASPSASWVSTSTSRASTSSDSGWASSSASWDSI 281
Query: 315 ------FSHGAIISTCQVSVDAPESKSESSNNRMNAWGTVSSSSNGGLNPSTLNSASNHG 368
A ++ S + S S SS+ ++ T+S S + S ++ S+ G
Sbjct: 282 TSDSGWVCPSASWASSSASWASAPSDSGSSSPSVSRASTLSVSGWASFSASGASAPSDSG 341
Query: 369 AWPVLENNGLALKGPVGSGS---SGINIQCSTIGQMPNNQSINSKVSGGST 416
W +G++ G S SG + + P+ + SG ST
Sbjct: 342 -WTSHSASGVSTTSDSGWASPSASGASTSSDSGWASPSASWASPSASGAST 391
Score = 33.5 bits (75), Expect = 2.1
Identities = 36/107 (33%), Positives = 43/107 (40%), Gaps = 21/107 (19%)
Query: 1868 PSPGWQSLGSSQSRLGSLDCSHSFSSRTDLNHWNGAGLSG--------TNCGDLHGTSLW 1919
PS W S GS+ L + SS ++ G SG T GD G L
Sbjct: 820 PSREWSSPGSTSGPLRPPPAAPVVSSAN--SYVMSMGSSGMLSSHSRTTASGDERGRELG 877
Query: 1920 GTPHYSTSLWGPP------SSSDPRGISSPSPINAFLSVD--HLGGG 1958
TP S+ WGPP SS PR P+P A L +D LG G
Sbjct: 878 DTPLASSCPWGPPPLLKVFSSDSPR---DPAPWLALLLLDAPELGPG 921
>gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1531
Score = 73.2 bits (178), Expect = 2e-12
Identities = 148/788 (18%), Positives = 274/788 (34%), Gaps = 100/788 (12%)
Query: 175 SSALTNQQPQNNGEVQNSKNQSDINHSTSGSHYENSQRGPVSSTSDSSTNCKNAVVSDLS 234
S TN + V ++ ST GS + +T+ S+T + V
Sbjct: 122 SETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAG 181
Query: 235 EKEAWPSAPGSDPELASECMDADSASSSESERNITIMASGNTGGEKDGLRNSTGLGSQNK 294
+ PS GS+ + S+ T+ +G+ + T S
Sbjct: 182 SETITPSTAGSE----------TTTVSTAGSETTTVSTTGSETTTASTAHSETTAAS--- 228
Query: 295 FVVGSSSNNVGHGSSTGPWGFSHGAIISTCQVSVDAPESKSESSNNRMNAWGTVSSSSNG 354
+GS + V S +ST A ++ +N +++S
Sbjct: 229 -TMGSETTKVSTAGSE--------TTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTT 279
Query: 355 GLNPSTLNSASNHGAWPVL------ENNGLALKGP----VGSGSSGI---------NIQC 395
G + +AS G+ P + E + GP V + SS + I+
Sbjct: 280 GFETT---AASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRA 336
Query: 396 STIG------QMPNNQSINSKVSGG--STHGTWGSLQETCESEVSGTQKVSFSGQPQNIT 447
ST+G +++ + + G ST T GS T +E S T S G + T
Sbjct: 337 STVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGS-EATT 395
Query: 448 TEMTGPNNTTNFMTSSLPNSGSVQNNELPSSNTGAWRVSTMNHPQMQAPSGMNGTSLSHL 507
TG TT +T S + + +E+ + +T + +T + G+ ++
Sbjct: 396 VSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTT---------ASTEGSEITIA 446
Query: 508 SNGESKSGGSYGTTWGAYGSNYSGDKCSGPNGQANGDTVNATLMQPGVNGPMGTNFQVNT 567
S +S++ TT GS + +G + T + T T F + +
Sbjct: 447 STSDSET-----TTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGS 501
Query: 568 NKGGGVWESGAANSQSTSWGSGNGANSGGSRRGWGTPAQNTGTNLPSVEWNKLPSNQHSN 627
+ E + S + ++ GS T TG+ +V L + S
Sbjct: 502 DTTTASTEGSETTAVSATGSEMTTVSTEGSE---NTTVSTTGSETTTVSTTGLETTTTST 558
Query: 628 DSANGNGKTFTNGWKSTEEEDQGSATSQTNEQSSVWAKTGGTVESDGSTESTGRLEEKGT 687
+ + T G ++T + +GS T+ + S T T +S+ +T ST E
Sbjct: 559 EGSEMT-TVSTTGAETTTDSTEGSGTTAASTAGSE-TTTVSTADSENTTASTADSETTSA 616
Query: 688 GESQSRDRRKIDQHTLLQSIVNRTDLDPRVLSNSGWGQTPIKQNTAWDTETSPRGERKTD 747
+ S + + T + S G T + + T S G +T
Sbjct: 617 STTGSE-----------TTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665
Query: 748 NGTEAWGSSATQTFNSGA-CIDKTSPNGNDTSSVSGWGDPKPALRWGDSKGSNCQGGWED 806
TE GS T +G+ T +G T S++G K + ++ ++ +G
Sbjct: 666 TSTE--GSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEIT 723
Query: 807 DSAATGMVKSNQWGNCKEEKAAWNDSQKNKQGWGDGQKSSQGWSVS-----ASDNWGETS 861
++ TG + E A + + G +++ + S AS ET+
Sbjct: 724 TASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETT 783
Query: 862 RNNHWGEANKKSSSGGS--------DSDRSVSGWNELGKTSSFTWGNNINPNNSSGWDES 913
+ G K S+ S +S+ +++ T+ T G+ P +++G E+
Sbjct: 784 MASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAG-SET 842
Query: 914 SKPTPSQG 921
+ T ++G
Sbjct: 843 TTTTSTEG 850
Score = 72.4 bits (176), Expect = 4e-12
Identities = 120/584 (20%), Positives = 214/584 (36%), Gaps = 30/584 (5%)
Query: 201 STSGSHYENSQRGPVSSTSDSSTNCKNAVVSDLSEKEAWPSAPGSDPELASECMDADSAS 260
+T+GS + + +T+ S+T + V + S GS+ S +
Sbjct: 467 TTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTV 526
Query: 261 SSESERNITIMASGNTGGEKDGLRNSTGLGSQNKFVVGSSSNNVGHGSSTGPWGFSHGAI 320
S+E N T+ +T G + ++TGL + GS V + + G+
Sbjct: 527 STEGSENTTV----STTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGS- 581
Query: 321 ISTCQVSVDAPESKSESSNNRMNAWGTVSSSSNGGLNPSTLNSASNHGAWPVLENNGLAL 380
T S E+ + S+ + N T S++ + + ST S + + E +
Sbjct: 582 -GTTAASTAGSETTTVSTADSENT--TASTADSETTSASTTGSETTTASTTSSETTTAST 638
Query: 381 KGPVGSGSSGINIQCSTIGQMPNNQSINSKVSGGSTHGTWGSLQETCESEVSGTQKVSFS 440
+G + S + + + + + ++I S +T + + T +E SGT VS +
Sbjct: 639 EGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSIT 698
Query: 441 GQPQNITTEMTGPNNTTNFMTSSLPNSGSVQNNELPSSNTGAWRVSTMNHPQMQAPSGMN 500
G + TG TT S + S+ +E +++T +T + G
Sbjct: 699 GS-ETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTT------ASTEGSE 751
Query: 501 GTSLSHLSNGESKSGGSYGTTWGAYGSNYSGDKCSGPNGQANGDTVNATLMQPGVNGPMG 560
TS S + GS TT S + G + T + M
Sbjct: 752 TTSAS--------TTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMT 803
Query: 561 TNFQVNTNKGGGVWESGAANSQSTSWGSGNGANSGGSRRGWGTPAQNTGTNLPSVEWNKL 620
T F N+ + + ST+ A++ GS T + + T S E ++
Sbjct: 804 TVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE- 862
Query: 621 PSNQHSNDSANGNGKTFTNGWKSTEEEDQGSATSQTNEQSSVWAKTGGTVESDGSTESTG 680
+ S +S+ T T G ++T +GS T+ T+ + S T T S+ +T ST
Sbjct: 863 -TTTASTESSETTTAT-TIGSETTTASTEGSETTTTSTEGSE-TTTASTEGSEITTVSTT 919
Query: 681 RLEEKGTGESQSRDRRKIDQHTLLQSIVNRTDLDPRVLSNSGWGQTPIKQNTAWDTETSP 740
E T ++ + + V+ T + +S G T + + T S
Sbjct: 920 G-SETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTAST 978
Query: 741 RGERKTDNGTEAWGSSATQTFNSGACIDKTSPNGNDTSSVSGWG 784
G T T GS T G+ S G++T++VS G
Sbjct: 979 AGSETTTVSTA--GSETTTASIEGSETTTVSSTGSETTTVSTTG 1020
Score = 42.0 bits (97), Expect = 0.006
Identities = 70/371 (18%), Positives = 134/371 (36%), Gaps = 18/371 (4%)
Query: 152 GQHFPVIAANLGSAVKVLNSQSESSALTNQQPQNNGEVQNSKNQSDINHSTSGSHYENSQ 211
G ++ + V SE++ +T + ++ ST+GS +
Sbjct: 940 GSELTTVSTTGSETITVSAEGSETTTVTTMGSETT--TASTAGSETTTVSTAGSETTTAS 997
Query: 212 RGPVSSTSDSSTNCKNAVVSDLSEKEAWPSAPGSDPELASECMDADSASSSESERNITIM 271
+T+ SST + VS + S GS+ + +A + T
Sbjct: 998 IEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTT- 1056
Query: 272 ASGNTGGEKDGLRNSTGLGSQNKFVVGSSSNNVGHGSSTGPWGFSHGAIISTCQVSVDAP 331
+T G + ++TG + + V S + G+ +T ++
Sbjct: 1057 ---STEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYIT---- 1109
Query: 332 ESKSESSNNRMNAWGTVSSSSNGGLNPSTLNSASNHGAWPVLENNGLALKGPVGSGSSGI 391
SK+ +++ + TVS++S+ ST S V E ++ G + SS
Sbjct: 1110 GSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAA 1169
Query: 392 NIQCSTIGQMPNNQSINSKV-SGGSTHGTWGSLQETCESEVSGTQKVSFSGQPQNITTEM 450
+ +T + + S S +T T GS T + S T S SG N T
Sbjct: 1170 GSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETN-TACT 1228
Query: 451 TGPNNTTNFMTSSLPNSGSVQNNELPSSNTGAWRVSTMNHPQMQAPSGMNGTSLSHLSNG 510
TG +T S N+ + +E ++T + P + +G T++S ++G
Sbjct: 1229 TGSETSTPSSAGSETNTAFIIGSETTIASTASL------EPTATSLTGSETTTVSITASG 1282
Query: 511 ESKSGGSYGTT 521
+ + + +T
Sbjct: 1283 ATAASTTVSST 1293
Score = 32.0 bits (71), Expect = 6.1
Identities = 53/281 (18%), Positives = 101/281 (35%), Gaps = 41/281 (14%)
Query: 170 NSQSESSALTNQQPQNNGEVQNSKNQSDINHSTSGSHYENSQRGPVSSTSDSSTNCKNAV 229
+S + S A T + ++ ST+GS + +T+ S++ +
Sbjct: 1166 SSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNT 1225
Query: 230 VSDLSEKEAWPSAPGSDPELA----SECMDADSASSSESERNITIMASGNTGGEKDGLRN 285
+ + PS+ GS+ A SE A +AS + ++T + G
Sbjct: 1226 ACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATA 1285
Query: 286 STGLGSQNKFVVGSSSNNVGHGSSTGPWGFSHGAIISTCQVSVDAPESKSESSNNRMNAW 345
++ S FV+ +++ + Q + P S + ++ R+ A
Sbjct: 1286 ASTTVSSTTFVLTKATD-------------------VSIQPITNTPMSGTRTTGTRLTAS 1326
Query: 346 GTVSSSSNGGLNPSTLNSASNHGAWPVLENNGLALKGPVGSGSSGINIQCSTIGQMPNNQ 405
+V+ + G++ T ++AS+ VL +GL ST+G
Sbjct: 1327 SSVTMAP--GMD-FTASAASHTVPGIVLNTSGLG---------------TSTMGASSTTS 1368
Query: 406 SINSKVSGGSTHGTWGSLQETCESEVSGTQKVSFSGQPQNI 446
+ + + GST S + GT VS S P N+
Sbjct: 1369 AHGVRTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTNV 1409
>gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1521
Score = 73.2 bits (178), Expect = 2e-12
Identities = 148/788 (18%), Positives = 274/788 (34%), Gaps = 100/788 (12%)
Query: 175 SSALTNQQPQNNGEVQNSKNQSDINHSTSGSHYENSQRGPVSSTSDSSTNCKNAVVSDLS 234
S TN + V ++ ST GS + +T+ S+T + V
Sbjct: 122 SETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAG 181
Query: 235 EKEAWPSAPGSDPELASECMDADSASSSESERNITIMASGNTGGEKDGLRNSTGLGSQNK 294
+ PS GS+ + S+ T+ +G+ + T S
Sbjct: 182 SETITPSTAGSE----------TTTVSTAGSETTTVSTTGSETTTASTAHSETTAAS--- 228
Query: 295 FVVGSSSNNVGHGSSTGPWGFSHGAIISTCQVSVDAPESKSESSNNRMNAWGTVSSSSNG 354
+GS + V S +ST A ++ +N +++S
Sbjct: 229 -TMGSETTKVSTAGSE--------TTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTT 279
Query: 355 GLNPSTLNSASNHGAWPVL------ENNGLALKGP----VGSGSSGI---------NIQC 395
G + +AS G+ P + E + GP V + SS + I+
Sbjct: 280 GFETT---AASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRA 336
Query: 396 STIG------QMPNNQSINSKVSGG--STHGTWGSLQETCESEVSGTQKVSFSGQPQNIT 447
ST+G +++ + + G ST T GS T +E S T S G + T
Sbjct: 337 STVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGS-EATT 395
Query: 448 TEMTGPNNTTNFMTSSLPNSGSVQNNELPSSNTGAWRVSTMNHPQMQAPSGMNGTSLSHL 507
TG TT +T S + + +E+ + +T + +T + G+ ++
Sbjct: 396 VSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTT---------ASTEGSEITIA 446
Query: 508 SNGESKSGGSYGTTWGAYGSNYSGDKCSGPNGQANGDTVNATLMQPGVNGPMGTNFQVNT 567
S +S++ TT GS + +G + T + T T F + +
Sbjct: 447 STSDSET-----TTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGS 501
Query: 568 NKGGGVWESGAANSQSTSWGSGNGANSGGSRRGWGTPAQNTGTNLPSVEWNKLPSNQHSN 627
+ E + S + ++ GS T TG+ +V L + S
Sbjct: 502 DTTTASTEGSETTAVSATGSEMTTVSTEGSE---NTTVSTTGSETTTVSTTGLETTTTST 558
Query: 628 DSANGNGKTFTNGWKSTEEEDQGSATSQTNEQSSVWAKTGGTVESDGSTESTGRLEEKGT 687
+ + T G ++T + +GS T+ + S T T +S+ +T ST E
Sbjct: 559 EGSEMT-TVSTTGAETTTDSTEGSGTTAASTAGSE-TTTVSTADSENTTASTADSETTSA 616
Query: 688 GESQSRDRRKIDQHTLLQSIVNRTDLDPRVLSNSGWGQTPIKQNTAWDTETSPRGERKTD 747
+ S + + T + S G T + + T S G +T
Sbjct: 617 STTGSE-----------TTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665
Query: 748 NGTEAWGSSATQTFNSGA-CIDKTSPNGNDTSSVSGWGDPKPALRWGDSKGSNCQGGWED 806
TE GS T +G+ T +G T S++G K + ++ ++ +G
Sbjct: 666 TSTE--GSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEIT 723
Query: 807 DSAATGMVKSNQWGNCKEEKAAWNDSQKNKQGWGDGQKSSQGWSVS-----ASDNWGETS 861
++ TG + E A + + G +++ + S AS ET+
Sbjct: 724 TASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETT 783
Query: 862 RNNHWGEANKKSSSGGS--------DSDRSVSGWNELGKTSSFTWGNNINPNNSSGWDES 913
+ G K S+ S +S+ +++ T+ T G+ P +++G E+
Sbjct: 784 MASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAG-SET 842
Query: 914 SKPTPSQG 921
+ T ++G
Sbjct: 843 TTTTSTEG 850
Score = 72.4 bits (176), Expect = 4e-12
Identities = 120/584 (20%), Positives = 214/584 (36%), Gaps = 30/584 (5%)
Query: 201 STSGSHYENSQRGPVSSTSDSSTNCKNAVVSDLSEKEAWPSAPGSDPELASECMDADSAS 260
+T+GS + + +T+ S+T + V + S GS+ S +
Sbjct: 467 TTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTV 526
Query: 261 SSESERNITIMASGNTGGEKDGLRNSTGLGSQNKFVVGSSSNNVGHGSSTGPWGFSHGAI 320
S+E N T+ +T G + ++TGL + GS V + + G+
Sbjct: 527 STEGSENTTV----STTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGS- 581
Query: 321 ISTCQVSVDAPESKSESSNNRMNAWGTVSSSSNGGLNPSTLNSASNHGAWPVLENNGLAL 380
T S E+ + S+ + N T S++ + + ST S + + E +
Sbjct: 582 -GTTAASTAGSETTTVSTADSENT--TASTADSETTSASTTGSETTTASTTSSETTTAST 638
Query: 381 KGPVGSGSSGINIQCSTIGQMPNNQSINSKVSGGSTHGTWGSLQETCESEVSGTQKVSFS 440
+G + S + + + + + ++I S +T + + T +E SGT VS +
Sbjct: 639 EGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSIT 698
Query: 441 GQPQNITTEMTGPNNTTNFMTSSLPNSGSVQNNELPSSNTGAWRVSTMNHPQMQAPSGMN 500
G + TG TT S + S+ +E +++T +T + G
Sbjct: 699 GS-ETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTT------ASTEGSE 751
Query: 501 GTSLSHLSNGESKSGGSYGTTWGAYGSNYSGDKCSGPNGQANGDTVNATLMQPGVNGPMG 560
TS S + GS TT S + G + T + M
Sbjct: 752 TTSAS--------TTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMT 803
Query: 561 TNFQVNTNKGGGVWESGAANSQSTSWGSGNGANSGGSRRGWGTPAQNTGTNLPSVEWNKL 620
T F N+ + + ST+ A++ GS T + + T S E ++
Sbjct: 804 TVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE- 862
Query: 621 PSNQHSNDSANGNGKTFTNGWKSTEEEDQGSATSQTNEQSSVWAKTGGTVESDGSTESTG 680
+ S +S+ T T G ++T +GS T+ T+ + S T T S+ +T ST
Sbjct: 863 -TTTASTESSETTTAT-TIGSETTTASTEGSETTTTSTEGSE-TTTASTEGSEITTVSTT 919
Query: 681 RLEEKGTGESQSRDRRKIDQHTLLQSIVNRTDLDPRVLSNSGWGQTPIKQNTAWDTETSP 740
E T ++ + + V+ T + +S G T + + T S
Sbjct: 920 G-SETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTAST 978
Query: 741 RGERKTDNGTEAWGSSATQTFNSGACIDKTSPNGNDTSSVSGWG 784
G T T GS T G+ S G++T++VS G
Sbjct: 979 AGSETTTVSTA--GSETTTASIEGSETTTVSSTGSETTTVSTTG 1020
Score = 40.4 bits (93), Expect = 0.017
Identities = 69/370 (18%), Positives = 134/370 (36%), Gaps = 26/370 (7%)
Query: 152 GQHFPVIAANLGSAVKVLNSQSESSALTNQQPQNNGEVQNSKNQSDINHSTSGSHYENSQ 211
G ++ + V SE++ +T + ++ ST+GS +
Sbjct: 940 GSELTTVSTTGSETITVSAEGSETTTVTTMGSETT--TASTAGSETTTVSTAGSETTTAS 997
Query: 212 RGPVSSTSDSSTNCKNAVVSDLSEKEAWPSAPGSDPELASECMDADSASSSESERNITIM 271
+T+ SST + VS + S GS+ + +A + T
Sbjct: 998 IEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTT- 1056
Query: 272 ASGNTGGEKDGLRNSTGLGSQNKFVVGSSSNNVGHGSSTGPWGFSHGAIISTCQVSVDAP 331
+T G + ++TG + + V S + G+ +T ++
Sbjct: 1057 ---STEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYIT---- 1109
Query: 332 ESKSESSNNRMNAWGTVSSSSNGGLNPSTLNSASNHGAWPVLENNGLALKGPVGSGSSGI 391
SK+ +++ + TVS++S+ ST S V E ++ G + SS
Sbjct: 1110 GSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAA 1169
Query: 392 NIQCSTIGQMPNNQSINSKVSGGSTHGTWGSLQETCESEVSGTQKVSFSGQPQNITTEMT 451
+ +T +++ S +T T GS T + S T S SG N T T
Sbjct: 1170 GSEATT---------TSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETN-TACTT 1219
Query: 452 GPNNTTNFMTSSLPNSGSVQNNELPSSNTGAWRVSTMNHPQMQAPSGMNGTSLSHLSNGE 511
G +T S N+ + +E ++T + P + +G T++S ++G
Sbjct: 1220 GSETSTPSSAGSETNTAFIIGSETTIASTASL------EPTATSLTGSETTTVSITASGA 1273
Query: 512 SKSGGSYGTT 521
+ + + +T
Sbjct: 1274 TAASTTVSST 1283
Score = 32.7 bits (73), Expect = 3.6
Identities = 52/276 (18%), Positives = 100/276 (36%), Gaps = 41/276 (14%)
Query: 175 SSALTNQQPQNNGEVQNSKNQSDINHSTSGSHYENSQRGPVSSTSDSSTNCKNAVVSDLS 234
S A T+ + +++ ST+GS + +T+ S++ +
Sbjct: 1161 SEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTG 1220
Query: 235 EKEAWPSAPGSDPELA----SECMDADSASSSESERNITIMASGNTGGEKDGLRNSTGLG 290
+ + PS+ GS+ A SE A +AS + ++T + G ++
Sbjct: 1221 SETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTV 1280
Query: 291 SQNKFVVGSSSNNVGHGSSTGPWGFSHGAIISTCQVSVDAPESKSESSNNRMNAWGTVSS 350
S FV+ +++ + Q + P S + ++ R+ A +V+
Sbjct: 1281 SSTTFVLTKATD-------------------VSIQPITNTPMSGTRTTGTRLTASSSVTM 1321
Query: 351 SSNGGLNPSTLNSASNHGAWPVLENNGLALKGPVGSGSSGINIQCSTIGQMPNNQSINSK 410
+ G++ T ++AS+ VL +GL ST+G + +
Sbjct: 1322 AP--GMD-FTASAASHTVPGIVLNTSGLG---------------TSTMGASSTTSAHGVR 1363
Query: 411 VSGGSTHGTWGSLQETCESEVSGTQKVSFSGQPQNI 446
+ GST S + GT VS S P N+
Sbjct: 1364 TTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTNV 1399
>gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1612
Score = 73.2 bits (178), Expect = 2e-12
Identities = 148/788 (18%), Positives = 274/788 (34%), Gaps = 100/788 (12%)
Query: 175 SSALTNQQPQNNGEVQNSKNQSDINHSTSGSHYENSQRGPVSSTSDSSTNCKNAVVSDLS 234
S TN + V ++ ST GS + +T+ S+T + V
Sbjct: 122 SETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAG 181
Query: 235 EKEAWPSAPGSDPELASECMDADSASSSESERNITIMASGNTGGEKDGLRNSTGLGSQNK 294
+ PS GS+ + S+ T+ +G+ + T S
Sbjct: 182 SETITPSTAGSE----------TTTVSTAGSETTTVSTTGSETTTASTAHSETTAAS--- 228
Query: 295 FVVGSSSNNVGHGSSTGPWGFSHGAIISTCQVSVDAPESKSESSNNRMNAWGTVSSSSNG 354
+GS + V S +ST A ++ +N +++S
Sbjct: 229 -TMGSETTKVSTAGSE--------TTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTT 279
Query: 355 GLNPSTLNSASNHGAWPVL------ENNGLALKGP----VGSGSSGI---------NIQC 395
G + +AS G+ P + E + GP V + SS + I+
Sbjct: 280 GFETT---AASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRA 336
Query: 396 STIG------QMPNNQSINSKVSGG--STHGTWGSLQETCESEVSGTQKVSFSGQPQNIT 447
ST+G +++ + + G ST T GS T +E S T S G + T
Sbjct: 337 STVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGS-EATT 395
Query: 448 TEMTGPNNTTNFMTSSLPNSGSVQNNELPSSNTGAWRVSTMNHPQMQAPSGMNGTSLSHL 507
TG TT +T S + + +E+ + +T + +T + G+ ++
Sbjct: 396 VSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTT---------ASTEGSEITIA 446
Query: 508 SNGESKSGGSYGTTWGAYGSNYSGDKCSGPNGQANGDTVNATLMQPGVNGPMGTNFQVNT 567
S +S++ TT GS + +G + T + T T F + +
Sbjct: 447 STSDSET-----TTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGS 501
Query: 568 NKGGGVWESGAANSQSTSWGSGNGANSGGSRRGWGTPAQNTGTNLPSVEWNKLPSNQHSN 627
+ E + S + ++ GS T TG+ +V L + S
Sbjct: 502 DTTTASTEGSETTAVSATGSEMTTVSTEGSE---NTTVSTTGSETTTVSTTGLETTTTST 558
Query: 628 DSANGNGKTFTNGWKSTEEEDQGSATSQTNEQSSVWAKTGGTVESDGSTESTGRLEEKGT 687
+ + T G ++T + +GS T+ + S T T +S+ +T ST E
Sbjct: 559 EGSEMT-TVSTTGAETTTDSTEGSGTTAASTAGSE-TTTVSTADSENTTASTADSETTSA 616
Query: 688 GESQSRDRRKIDQHTLLQSIVNRTDLDPRVLSNSGWGQTPIKQNTAWDTETSPRGERKTD 747
+ S + + T + S G T + + T S G +T
Sbjct: 617 STTGSE-----------TTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665
Query: 748 NGTEAWGSSATQTFNSGA-CIDKTSPNGNDTSSVSGWGDPKPALRWGDSKGSNCQGGWED 806
TE GS T +G+ T +G T S++G K + ++ ++ +G
Sbjct: 666 TSTE--GSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEIT 723
Query: 807 DSAATGMVKSNQWGNCKEEKAAWNDSQKNKQGWGDGQKSSQGWSVS-----ASDNWGETS 861
++ TG + E A + + G +++ + S AS ET+
Sbjct: 724 TASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETT 783
Query: 862 RNNHWGEANKKSSSGGS--------DSDRSVSGWNELGKTSSFTWGNNINPNNSSGWDES 913
+ G K S+ S +S+ +++ T+ T G+ P +++G E+
Sbjct: 784 MASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAG-SET 842
Query: 914 SKPTPSQG 921
+ T ++G
Sbjct: 843 TTTTSTEG 850
Score = 72.4 bits (176), Expect = 4e-12
Identities = 120/584 (20%), Positives = 214/584 (36%), Gaps = 30/584 (5%)
Query: 201 STSGSHYENSQRGPVSSTSDSSTNCKNAVVSDLSEKEAWPSAPGSDPELASECMDADSAS 260
+T+GS + + +T+ S+T + V + S GS+ S +
Sbjct: 467 TTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTV 526
Query: 261 SSESERNITIMASGNTGGEKDGLRNSTGLGSQNKFVVGSSSNNVGHGSSTGPWGFSHGAI 320
S+E N T+ +T G + ++TGL + GS V + + G+
Sbjct: 527 STEGSENTTV----STTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGS- 581
Query: 321 ISTCQVSVDAPESKSESSNNRMNAWGTVSSSSNGGLNPSTLNSASNHGAWPVLENNGLAL 380
T S E+ + S+ + N T S++ + + ST S + + E +
Sbjct: 582 -GTTAASTAGSETTTVSTADSENT--TASTADSETTSASTTGSETTTASTTSSETTTAST 638
Query: 381 KGPVGSGSSGINIQCSTIGQMPNNQSINSKVSGGSTHGTWGSLQETCESEVSGTQKVSFS 440
+G + S + + + + + ++I S +T + + T +E SGT VS +
Sbjct: 639 EGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSIT 698
Query: 441 GQPQNITTEMTGPNNTTNFMTSSLPNSGSVQNNELPSSNTGAWRVSTMNHPQMQAPSGMN 500
G + TG TT S + S+ +E +++T +T + G
Sbjct: 699 GS-ETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTT------ASTEGSE 751
Query: 501 GTSLSHLSNGESKSGGSYGTTWGAYGSNYSGDKCSGPNGQANGDTVNATLMQPGVNGPMG 560
TS S + GS TT S + G + T + M
Sbjct: 752 TTSAS--------TTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMT 803
Query: 561 TNFQVNTNKGGGVWESGAANSQSTSWGSGNGANSGGSRRGWGTPAQNTGTNLPSVEWNKL 620
T F N+ + + ST+ A++ GS T + + T S E ++
Sbjct: 804 TVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE- 862
Query: 621 PSNQHSNDSANGNGKTFTNGWKSTEEEDQGSATSQTNEQSSVWAKTGGTVESDGSTESTG 680
+ S +S+ T T G ++T +GS T+ T+ + S T T S+ +T ST
Sbjct: 863 -TTTASTESSETTTAT-TIGSETTTASTEGSETTTTSTEGSE-TTTASTEGSEITTVSTT 919
Query: 681 RLEEKGTGESQSRDRRKIDQHTLLQSIVNRTDLDPRVLSNSGWGQTPIKQNTAWDTETSP 740
E T ++ + + V+ T + +S G T + + T S
Sbjct: 920 G-SETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTAST 978
Query: 741 RGERKTDNGTEAWGSSATQTFNSGACIDKTSPNGNDTSSVSGWG 784
G T T GS T G+ S G++T++VS G
Sbjct: 979 AGSETTTVSTA--GSETTTASIEGSETTTVSSTGSETTTVSTTG 1020
Score = 41.6 bits (96), Expect = 0.008
Identities = 82/454 (18%), Positives = 153/454 (33%), Gaps = 48/454 (10%)
Query: 152 GQHFPVIAANLGSAVKVLNSQSESSALTNQQPQNNGEVQNSKNQSDINHSTSGSHYENSQ 211
G ++ + V SE++ +T + ++ ST+GS +
Sbjct: 940 GSELTTVSTTGSETITVSAEGSETTTVTTMGSETT--TASTAGSETTTVSTAGSETTTAS 997
Query: 212 RGPVSSTSDSSTNCKNAVVSDLSEKEAWPSAPGSDPELASECMDADSA----------SS 261
+T+ SST + VS + S GS+ + +A +S
Sbjct: 998 IEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTS 1057
Query: 262 SESERNITIMASG------NTGGEKDGLRNSTGLGSQNKFVVGSSSNNVGHGSSTGPWGF 315
+E T+ +G +T + +++G G+ GS + V S
Sbjct: 1058 TEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTAS 1117
Query: 316 SHGAIISTCQVSVDAPESKSESSNNRMNAWGTVSSS---SNGGLNPSTLNSASNHGAWPV 372
+ G+ +T + + S + + + TVS + S G +T ++A +
Sbjct: 1118 TEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTS 1177
Query: 373 LENNGLALKGPVGS-----------------GSSGINIQCSTIGQMPNNQSINSK----- 410
E + GS S N C+T + S S+
Sbjct: 1178 TEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAF 1237
Query: 411 -VSGGSTHGTWGSLQETCESEVSGTQKVSFSGQPQNITTEMTGPNNTTNFMTSSLPNS-G 468
+ ST + SL+ T S ++G++ + S T T ++TT +T + S
Sbjct: 1238 IIGSESTIASTASLEPTATS-LTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQ 1296
Query: 469 SVQNNELPSSNTGAWRVSTMNHPQMQAPSGMNGTSLSHLSNGESKSGGSYGTTWGAYGSN 528
+ N + + T R++ + M ++ SH G + GT+ S
Sbjct: 1297 PITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASST 1356
Query: 529 YSGDKCSGPNGQANGDTVNATLMQPGVNGPMGTN 562
S G T ++T + G MGTN
Sbjct: 1357 TSAHGVRTTTGSTREPT-SSTFQETGPVS-MGTN 1388
Score = 32.7 bits (73), Expect = 3.6
Identities = 52/276 (18%), Positives = 100/276 (36%), Gaps = 41/276 (14%)
Query: 175 SSALTNQQPQNNGEVQNSKNQSDINHSTSGSHYENSQRGPVSSTSDSSTNCKNAVVSDLS 234
S A T+ + +++ ST+GS + +T+ S++ +
Sbjct: 1161 SEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTG 1220
Query: 235 EKEAWPSAPGSDPELA----SECMDADSASSSESERNITIMASGNTGGEKDGLRNSTGLG 290
+ + PS+ GS+ A SE A +AS + ++T + G ++
Sbjct: 1221 SETSTPSSAGSETNTAFIIGSESTIASTASLEPTATSLTGSETTTVSITASGATAASTTV 1280
Query: 291 SQNKFVVGSSSNNVGHGSSTGPWGFSHGAIISTCQVSVDAPESKSESSNNRMNAWGTVSS 350
S FV+ +++ + Q + P S + ++ R+ A +V+
Sbjct: 1281 SSTTFVLTKATD-------------------VSIQPITNTPMSGTRTTGTRLTASSSVTM 1321
Query: 351 SSNGGLNPSTLNSASNHGAWPVLENNGLALKGPVGSGSSGINIQCSTIGQMPNNQSINSK 410
+ G++ T ++AS+ VL +GL ST+G + +
Sbjct: 1322 AP--GMD-FTASAASHTVPGIVLNTSGLG---------------TSTMGASSTTSAHGVR 1363
Query: 411 VSGGSTHGTWGSLQETCESEVSGTQKVSFSGQPQNI 446
+ GST S + GT VS S P N+
Sbjct: 1364 TTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTNV 1399
>gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1542
Score = 73.2 bits (178), Expect = 2e-12
Identities = 148/788 (18%), Positives = 274/788 (34%), Gaps = 100/788 (12%)
Query: 175 SSALTNQQPQNNGEVQNSKNQSDINHSTSGSHYENSQRGPVSSTSDSSTNCKNAVVSDLS 234
S TN + V ++ ST GS + +T+ S+T + V
Sbjct: 143 SETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAG 202
Query: 235 EKEAWPSAPGSDPELASECMDADSASSSESERNITIMASGNTGGEKDGLRNSTGLGSQNK 294
+ PS GS+ + S+ T+ +G+ + T S
Sbjct: 203 SETITPSTAGSE----------TTTVSTAGSETTTVSTTGSETTTASTAHSETTAAS--- 249
Query: 295 FVVGSSSNNVGHGSSTGPWGFSHGAIISTCQVSVDAPESKSESSNNRMNAWGTVSSSSNG 354
+GS + V S +ST A ++ +N +++S
Sbjct: 250 -TMGSETTKVSTAGSE--------TTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTT 300
Query: 355 GLNPSTLNSASNHGAWPVL------ENNGLALKGP----VGSGSSGI---------NIQC 395
G + +AS G+ P + E + GP V + SS + I+
Sbjct: 301 GFETT---AASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRA 357
Query: 396 STIG------QMPNNQSINSKVSGG--STHGTWGSLQETCESEVSGTQKVSFSGQPQNIT 447
ST+G +++ + + G ST T GS T +E S T S G + T
Sbjct: 358 STVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGS-EATT 416
Query: 448 TEMTGPNNTTNFMTSSLPNSGSVQNNELPSSNTGAWRVSTMNHPQMQAPSGMNGTSLSHL 507
TG TT +T S + + +E+ + +T + +T + G+ ++
Sbjct: 417 VSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTT---------ASTEGSEITIA 467
Query: 508 SNGESKSGGSYGTTWGAYGSNYSGDKCSGPNGQANGDTVNATLMQPGVNGPMGTNFQVNT 567
S +S++ TT GS + +G + T + T T F + +
Sbjct: 468 STSDSET-----TTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGS 522
Query: 568 NKGGGVWESGAANSQSTSWGSGNGANSGGSRRGWGTPAQNTGTNLPSVEWNKLPSNQHSN 627
+ E + S + ++ GS T TG+ +V L + S
Sbjct: 523 DTTTASTEGSETTAVSATGSEMTTVSTEGSE---NTTVSTTGSETTTVSTTGLETTTTST 579
Query: 628 DSANGNGKTFTNGWKSTEEEDQGSATSQTNEQSSVWAKTGGTVESDGSTESTGRLEEKGT 687
+ + T G ++T + +GS T+ + S T T +S+ +T ST E
Sbjct: 580 EGSEMT-TVSTTGAETTTDSTEGSGTTAASTAGSE-TTTVSTADSENTTASTADSETTSA 637
Query: 688 GESQSRDRRKIDQHTLLQSIVNRTDLDPRVLSNSGWGQTPIKQNTAWDTETSPRGERKTD 747
+ S + + T + S G T + + T S G +T
Sbjct: 638 STTGSE-----------TTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 686
Query: 748 NGTEAWGSSATQTFNSGA-CIDKTSPNGNDTSSVSGWGDPKPALRWGDSKGSNCQGGWED 806
TE GS T +G+ T +G T S++G K + ++ ++ +G
Sbjct: 687 TSTE--GSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEIT 744
Query: 807 DSAATGMVKSNQWGNCKEEKAAWNDSQKNKQGWGDGQKSSQGWSVS-----ASDNWGETS 861
++ TG + E A + + G +++ + S AS ET+
Sbjct: 745 TASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETT 804
Query: 862 RNNHWGEANKKSSSGGS--------DSDRSVSGWNELGKTSSFTWGNNINPNNSSGWDES 913
+ G K S+ S +S+ +++ T+ T G+ P +++G E+
Sbjct: 805 MASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAG-SET 863
Query: 914 SKPTPSQG 921
+ T ++G
Sbjct: 864 TTTTSTEG 871
Score = 72.4 bits (176), Expect = 4e-12
Identities = 120/584 (20%), Positives = 214/584 (36%), Gaps = 30/584 (5%)
Query: 201 STSGSHYENSQRGPVSSTSDSSTNCKNAVVSDLSEKEAWPSAPGSDPELASECMDADSAS 260
+T+GS + + +T+ S+T + V + S GS+ S +
Sbjct: 488 TTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTV 547
Query: 261 SSESERNITIMASGNTGGEKDGLRNSTGLGSQNKFVVGSSSNNVGHGSSTGPWGFSHGAI 320
S+E N T+ +T G + ++TGL + GS V + + G+
Sbjct: 548 STEGSENTTV----STTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGS- 602
Query: 321 ISTCQVSVDAPESKSESSNNRMNAWGTVSSSSNGGLNPSTLNSASNHGAWPVLENNGLAL 380
T S E+ + S+ + N T S++ + + ST S + + E +
Sbjct: 603 -GTTAASTAGSETTTVSTADSENT--TASTADSETTSASTTGSETTTASTTSSETTTAST 659
Query: 381 KGPVGSGSSGINIQCSTIGQMPNNQSINSKVSGGSTHGTWGSLQETCESEVSGTQKVSFS 440
+G + S + + + + + ++I S +T + + T +E SGT VS +
Sbjct: 660 EGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSIT 719
Query: 441 GQPQNITTEMTGPNNTTNFMTSSLPNSGSVQNNELPSSNTGAWRVSTMNHPQMQAPSGMN 500
G + TG TT S + S+ +E +++T +T + G
Sbjct: 720 GS-ETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTT------ASTEGSE 772
Query: 501 GTSLSHLSNGESKSGGSYGTTWGAYGSNYSGDKCSGPNGQANGDTVNATLMQPGVNGPMG 560
TS S + GS TT S + G + T + M
Sbjct: 773 TTSAS--------TTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMT 824
Query: 561 TNFQVNTNKGGGVWESGAANSQSTSWGSGNGANSGGSRRGWGTPAQNTGTNLPSVEWNKL 620
T F N+ + + ST+ A++ GS T + + T S E ++
Sbjct: 825 TVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE- 883
Query: 621 PSNQHSNDSANGNGKTFTNGWKSTEEEDQGSATSQTNEQSSVWAKTGGTVESDGSTESTG 680
+ S +S+ T T G ++T +GS T+ T+ + S T T S+ +T ST
Sbjct: 884 -TTTASTESSETTTAT-TIGSETTTASTEGSETTTTSTEGSE-TTTASTEGSEITTVSTT 940
Query: 681 RLEEKGTGESQSRDRRKIDQHTLLQSIVNRTDLDPRVLSNSGWGQTPIKQNTAWDTETSP 740
E T ++ + + V+ T + +S G T + + T S
Sbjct: 941 G-SETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTAST 999
Query: 741 RGERKTDNGTEAWGSSATQTFNSGACIDKTSPNGNDTSSVSGWG 784
G T T GS T G+ S G++T++VS G
Sbjct: 1000 AGSETTTVSTA--GSETTTASIEGSETTTVSSTGSETTTVSTTG 1041
Score = 40.4 bits (93), Expect = 0.017
Identities = 69/370 (18%), Positives = 134/370 (36%), Gaps = 26/370 (7%)
Query: 152 GQHFPVIAANLGSAVKVLNSQSESSALTNQQPQNNGEVQNSKNQSDINHSTSGSHYENSQ 211
G ++ + V SE++ +T + ++ ST+GS +
Sbjct: 961 GSELTTVSTTGSETITVSAEGSETTTVTTMGSETT--TASTAGSETTTVSTAGSETTTAS 1018
Query: 212 RGPVSSTSDSSTNCKNAVVSDLSEKEAWPSAPGSDPELASECMDADSASSSESERNITIM 271
+T+ SST + VS + S GS+ + +A + T
Sbjct: 1019 IEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTT- 1077
Query: 272 ASGNTGGEKDGLRNSTGLGSQNKFVVGSSSNNVGHGSSTGPWGFSHGAIISTCQVSVDAP 331
+T G + ++TG + + V S + G+ +T ++
Sbjct: 1078 ---STEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYIT---- 1130
Query: 332 ESKSESSNNRMNAWGTVSSSSNGGLNPSTLNSASNHGAWPVLENNGLALKGPVGSGSSGI 391
SK+ +++ + TVS++S+ ST S V E ++ G + SS
Sbjct: 1131 GSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAA 1190
Query: 392 NIQCSTIGQMPNNQSINSKVSGGSTHGTWGSLQETCESEVSGTQKVSFSGQPQNITTEMT 451
+ +T +++ S +T T GS T + S T S SG N T T
Sbjct: 1191 GSEATT---------TSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETN-TACTT 1240
Query: 452 GPNNTTNFMTSSLPNSGSVQNNELPSSNTGAWRVSTMNHPQMQAPSGMNGTSLSHLSNGE 511
G +T S N+ + +E ++T + P + +G T++S ++G
Sbjct: 1241 GSETSTPSSAGSETNTAFIIGSETTIASTASL------EPTATSLTGSETTTVSITASGA 1294
Query: 512 SKSGGSYGTT 521
+ + + +T
Sbjct: 1295 TAASTTVSST 1304
Score = 32.7 bits (73), Expect = 3.6
Identities = 52/276 (18%), Positives = 100/276 (36%), Gaps = 41/276 (14%)
Query: 175 SSALTNQQPQNNGEVQNSKNQSDINHSTSGSHYENSQRGPVSSTSDSSTNCKNAVVSDLS 234
S A T+ + +++ ST+GS + +T+ S++ +
Sbjct: 1182 SEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTG 1241
Query: 235 EKEAWPSAPGSDPELA----SECMDADSASSSESERNITIMASGNTGGEKDGLRNSTGLG 290
+ + PS+ GS+ A SE A +AS + ++T + G ++
Sbjct: 1242 SETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTV 1301
Query: 291 SQNKFVVGSSSNNVGHGSSTGPWGFSHGAIISTCQVSVDAPESKSESSNNRMNAWGTVSS 350
S FV+ +++ + Q + P S + ++ R+ A +V+
Sbjct: 1302 SSTTFVLTKATD-------------------VSIQPITNTPMSGTRTTGTRLTASSSVTM 1342
Query: 351 SSNGGLNPSTLNSASNHGAWPVLENNGLALKGPVGSGSSGINIQCSTIGQMPNNQSINSK 410
+ G++ T ++AS+ VL +GL ST+G + +
Sbjct: 1343 AP--GMD-FTASAASHTVPGIVLNTSGLG---------------TSTMGASSTTSAHGVR 1384
Query: 411 VSGGSTHGTWGSLQETCESEVSGTQKVSFSGQPQNI 446
+ GST S + GT VS S P N+
Sbjct: 1385 TTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTNV 1420
>gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1612
Score = 73.2 bits (178), Expect = 2e-12
Identities = 148/788 (18%), Positives = 274/788 (34%), Gaps = 100/788 (12%)
Query: 175 SSALTNQQPQNNGEVQNSKNQSDINHSTSGSHYENSQRGPVSSTSDSSTNCKNAVVSDLS 234
S TN + V ++ ST GS + +T+ S+T + V
Sbjct: 122 SETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAG 181
Query: 235 EKEAWPSAPGSDPELASECMDADSASSSESERNITIMASGNTGGEKDGLRNSTGLGSQNK 294
+ PS GS+ + S+ T+ +G+ + T S
Sbjct: 182 SETITPSTAGSE----------TTTVSTAGSETTTVSTTGSETTTASTAHSETTAAS--- 228
Query: 295 FVVGSSSNNVGHGSSTGPWGFSHGAIISTCQVSVDAPESKSESSNNRMNAWGTVSSSSNG 354
+GS + V S +ST A ++ +N +++S
Sbjct: 229 -TMGSETTKVSTAGSE--------TTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTT 279
Query: 355 GLNPSTLNSASNHGAWPVL------ENNGLALKGP----VGSGSSGI---------NIQC 395
G + +AS G+ P + E + GP V + SS + I+
Sbjct: 280 GFETT---AASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRA 336
Query: 396 STIG------QMPNNQSINSKVSGG--STHGTWGSLQETCESEVSGTQKVSFSGQPQNIT 447
ST+G +++ + + G ST T GS T +E S T S G + T
Sbjct: 337 STVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGS-EATT 395
Query: 448 TEMTGPNNTTNFMTSSLPNSGSVQNNELPSSNTGAWRVSTMNHPQMQAPSGMNGTSLSHL 507
TG TT +T S + + +E+ + +T + +T + G+ ++
Sbjct: 396 VSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTT---------ASTEGSEITIA 446
Query: 508 SNGESKSGGSYGTTWGAYGSNYSGDKCSGPNGQANGDTVNATLMQPGVNGPMGTNFQVNT 567
S +S++ TT GS + +G + T + T T F + +
Sbjct: 447 STSDSET-----TTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGS 501
Query: 568 NKGGGVWESGAANSQSTSWGSGNGANSGGSRRGWGTPAQNTGTNLPSVEWNKLPSNQHSN 627
+ E + S + ++ GS T TG+ +V L + S
Sbjct: 502 DTTTASTEGSETTAVSATGSEMTTVSTEGSE---NTTVSTTGSETTTVSTTGLETTTTST 558
Query: 628 DSANGNGKTFTNGWKSTEEEDQGSATSQTNEQSSVWAKTGGTVESDGSTESTGRLEEKGT 687
+ + T G ++T + +GS T+ + S T T +S+ +T ST E
Sbjct: 559 EGSEMT-TVSTTGAETTTDSTEGSGTTAASTAGSE-TTTVSTADSENTTASTADSETTSA 616
Query: 688 GESQSRDRRKIDQHTLLQSIVNRTDLDPRVLSNSGWGQTPIKQNTAWDTETSPRGERKTD 747
+ S + + T + S G T + + T S G +T
Sbjct: 617 STTGSE-----------TTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665
Query: 748 NGTEAWGSSATQTFNSGA-CIDKTSPNGNDTSSVSGWGDPKPALRWGDSKGSNCQGGWED 806
TE GS T +G+ T +G T S++G K + ++ ++ +G
Sbjct: 666 TSTE--GSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEIT 723
Query: 807 DSAATGMVKSNQWGNCKEEKAAWNDSQKNKQGWGDGQKSSQGWSVS-----ASDNWGETS 861
++ TG + E A + + G +++ + S AS ET+
Sbjct: 724 TASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETT 783
Query: 862 RNNHWGEANKKSSSGGS--------DSDRSVSGWNELGKTSSFTWGNNINPNNSSGWDES 913
+ G K S+ S +S+ +++ T+ T G+ P +++G E+
Sbjct: 784 MASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAG-SET 842
Query: 914 SKPTPSQG 921
+ T ++G
Sbjct: 843 TTTTSTEG 850
Score = 72.4 bits (176), Expect = 4e-12
Identities = 120/584 (20%), Positives = 214/584 (36%), Gaps = 30/584 (5%)
Query: 201 STSGSHYENSQRGPVSSTSDSSTNCKNAVVSDLSEKEAWPSAPGSDPELASECMDADSAS 260
+T+GS + + +T+ S+T + V + S GS+ S +
Sbjct: 467 TTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTV 526
Query: 261 SSESERNITIMASGNTGGEKDGLRNSTGLGSQNKFVVGSSSNNVGHGSSTGPWGFSHGAI 320
S+E N T+ +T G + ++TGL + GS V + + G+
Sbjct: 527 STEGSENTTV----STTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGS- 581
Query: 321 ISTCQVSVDAPESKSESSNNRMNAWGTVSSSSNGGLNPSTLNSASNHGAWPVLENNGLAL 380
T S E+ + S+ + N T S++ + + ST S + + E +
Sbjct: 582 -GTTAASTAGSETTTVSTADSENT--TASTADSETTSASTTGSETTTASTTSSETTTAST 638
Query: 381 KGPVGSGSSGINIQCSTIGQMPNNQSINSKVSGGSTHGTWGSLQETCESEVSGTQKVSFS 440
+G + S + + + + + ++I S +T + + T +E SGT VS +
Sbjct: 639 EGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSIT 698
Query: 441 GQPQNITTEMTGPNNTTNFMTSSLPNSGSVQNNELPSSNTGAWRVSTMNHPQMQAPSGMN 500
G + TG TT S + S+ +E +++T +T + G
Sbjct: 699 GS-ETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTT------ASTEGSE 751
Query: 501 GTSLSHLSNGESKSGGSYGTTWGAYGSNYSGDKCSGPNGQANGDTVNATLMQPGVNGPMG 560
TS S + GS TT S + G + T + M
Sbjct: 752 TTSAS--------TTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMT 803
Query: 561 TNFQVNTNKGGGVWESGAANSQSTSWGSGNGANSGGSRRGWGTPAQNTGTNLPSVEWNKL 620
T F N+ + + ST+ A++ GS T + + T S E ++
Sbjct: 804 TVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE- 862
Query: 621 PSNQHSNDSANGNGKTFTNGWKSTEEEDQGSATSQTNEQSSVWAKTGGTVESDGSTESTG 680
+ S +S+ T T G ++T +GS T+ T+ + S T T S+ +T ST
Sbjct: 863 -TTTASTESSETTTAT-TIGSETTTASTEGSETTTTSTEGSE-TTTASTEGSEITTVSTT 919
Query: 681 RLEEKGTGESQSRDRRKIDQHTLLQSIVNRTDLDPRVLSNSGWGQTPIKQNTAWDTETSP 740
E T ++ + + V+ T + +S G T + + T S
Sbjct: 920 G-SETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTAST 978
Query: 741 RGERKTDNGTEAWGSSATQTFNSGACIDKTSPNGNDTSSVSGWG 784
G T T GS T G+ S G++T++VS G
Sbjct: 979 AGSETTTVSTA--GSETTTASIEGSETTTVSSTGSETTTVSTTG 1020
Score = 41.2 bits (95), Expect = 0.010
Identities = 89/471 (18%), Positives = 165/471 (35%), Gaps = 42/471 (8%)
Query: 152 GQHFPVIAANLGSAVKVLNSQSESSALTNQQPQNNGEVQNSKNQSDINHSTSGSHYENSQ 211
G ++ + V SE++ +T + ++ ST+GS +
Sbjct: 940 GSELTTVSTTGSETITVSAEGSETTTVTTMGSETT--TASTAGSETTTVSTAGSETTTAS 997
Query: 212 RGPVSSTSDSSTNCKNAVVSDLSEKEAWPSAPGSDPELASECMDADSASSSESERNITIM 271
+T+ SST + VS + S GS+ + +A + T
Sbjct: 998 IEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTT- 1056
Query: 272 ASGNTGGEKDGLRNSTGLGSQNKFVVGSSSNNVGHGSSTGPWGFSHGAIISTCQVSVDAP 331
+T G + ++TG + + V S + G+ +T ++
Sbjct: 1057 ---STEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYIT---- 1109
Query: 332 ESKSESSNNRMNAWGTVSSSSNGGLNPSTLNSASNHGAWPVLENNGLALKGPVGSGSSGI 391
SK+ +++ + TVS++S+ ST S V E ++ G + SS
Sbjct: 1110 GSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAA 1169
Query: 392 NIQCSTIGQMPNNQSINSKVSGGSTHGTWGSLQETCESEVSGTQKVSFSGQPQNITTEMT 451
+ +T +++ S +T T GS T + S T S SG N T T
Sbjct: 1170 GSEATT---------TSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETN-TACTT 1219
Query: 452 GPNNTTNFMTSSLPNSGSVQNNELPSSNTGAWRVSTMNHPQMQAPSGMNGTSLSHLSNGE 511
G +T S N+ + +E ++T + P + +G T++S ++G
Sbjct: 1220 GSETSTPSSAGSETNTAFIIGSETTIASTASL------EPTATSLTGSETTTVSITASGA 1273
Query: 512 SKSGGSYGTTWGAY------------GSNYSGDKCSGPNGQANGDTVNATLMQPGVNGPM 559
+ + + +T + SG + +G A+ A M +
Sbjct: 1274 TAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRPTASSSVTMAPGMDFTASAAS 1333
Query: 560 GTNFQVNTNKGG-GVWESGAANSQSTSWGSGNGANSGGSRRGWGTPAQNTG 609
T + N G G GA+ ST+ G +G +R + Q TG
Sbjct: 1334 HTVPGIVLNTSGLGTSTMGAS---STTSAHGVRTTTGSTREPTSSTFQETG 1381
Score = 37.0 bits (84), Expect = 0.19
Identities = 53/251 (21%), Positives = 91/251 (36%), Gaps = 20/251 (7%)
Query: 215 VSSTSDSSTNCKNAVVSDLSEKEAWP-SAPGSDPELASECMDADSASSSESERNITIMAS 273
VS T+ ST A S + EA S GS+ AS + +S+ T S
Sbjct: 1150 VSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTS 1209
Query: 274 GN------TGGEKDGLRNSTGLGSQNKFVVGSSSNNVGHGSSTGPWGFS-HGAIISTCQV 326
G+ T G + +S G + F++GS + + +S P S G+ +T +
Sbjct: 1210 GSETNTACTTGSETSTPSSAGSETNTAFIIGSETT-IASTASLEPTATSLTGSETTTVSI 1268
Query: 327 SVDAPESKSESSNNRMNAWGTVSSSSNGGLNPSTLNSASNHGAWPVLENNGLALKGPVGS 386
+ + S + ++ + S + + ++ G P ++ G +
Sbjct: 1269 TASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRPTASSSVTMAPGMDFT 1328
Query: 387 GSSGIN----IQCSTIGQMPNNQSINSKVSGGSTHGTWGSLQETCESEVS-------GTQ 435
S+ + I +T G + +S S T GS +E S GT
Sbjct: 1329 ASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREPTSSTFQETGPVSMGTN 1388
Query: 436 KVSFSGQPQNI 446
VS S P N+
Sbjct: 1389 TVSMSHTPTNV 1399
>gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1704
Score = 73.2 bits (178), Expect = 2e-12
Identities = 148/788 (18%), Positives = 274/788 (34%), Gaps = 100/788 (12%)
Query: 175 SSALTNQQPQNNGEVQNSKNQSDINHSTSGSHYENSQRGPVSSTSDSSTNCKNAVVSDLS 234
S TN + V ++ ST GS + +T+ S+T + V
Sbjct: 122 SETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAG 181
Query: 235 EKEAWPSAPGSDPELASECMDADSASSSESERNITIMASGNTGGEKDGLRNSTGLGSQNK 294
+ PS GS+ + S+ T+ +G+ + T S
Sbjct: 182 SETITPSTAGSE----------TTTVSTAGSETTTVSTTGSETTTASTAHSETTAAS--- 228
Query: 295 FVVGSSSNNVGHGSSTGPWGFSHGAIISTCQVSVDAPESKSESSNNRMNAWGTVSSSSNG 354
+GS + V S +ST A ++ +N +++S
Sbjct: 229 -TMGSETTKVSTAGSE--------TTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTT 279
Query: 355 GLNPSTLNSASNHGAWPVL------ENNGLALKGP----VGSGSSGI---------NIQC 395
G + +AS G+ P + E + GP V + SS + I+
Sbjct: 280 GFETT---AASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRA 336
Query: 396 STIG------QMPNNQSINSKVSGG--STHGTWGSLQETCESEVSGTQKVSFSGQPQNIT 447
ST+G +++ + + G ST T GS T +E S T S G + T
Sbjct: 337 STVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGS-EATT 395
Query: 448 TEMTGPNNTTNFMTSSLPNSGSVQNNELPSSNTGAWRVSTMNHPQMQAPSGMNGTSLSHL 507
TG TT +T S + + +E+ + +T + +T + G+ ++
Sbjct: 396 VSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTT---------ASTEGSEITIA 446
Query: 508 SNGESKSGGSYGTTWGAYGSNYSGDKCSGPNGQANGDTVNATLMQPGVNGPMGTNFQVNT 567
S +S++ TT GS + +G + T + T T F + +
Sbjct: 447 STSDSET-----TTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGS 501
Query: 568 NKGGGVWESGAANSQSTSWGSGNGANSGGSRRGWGTPAQNTGTNLPSVEWNKLPSNQHSN 627
+ E + S + ++ GS T TG+ +V L + S
Sbjct: 502 DTTTASTEGSETTAVSATGSEMTTVSTEGSE---NTTVSTTGSETTTVSTTGLETTTTST 558
Query: 628 DSANGNGKTFTNGWKSTEEEDQGSATSQTNEQSSVWAKTGGTVESDGSTESTGRLEEKGT 687
+ + T G ++T + +GS T+ + S T T +S+ +T ST E
Sbjct: 559 EGSEMT-TVSTTGAETTTDSTEGSGTTAASTAGSE-TTTVSTADSENTTASTADSETTSA 616
Query: 688 GESQSRDRRKIDQHTLLQSIVNRTDLDPRVLSNSGWGQTPIKQNTAWDTETSPRGERKTD 747
+ S + + T + S G T + + T S G +T
Sbjct: 617 STTGSE-----------TTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665
Query: 748 NGTEAWGSSATQTFNSGA-CIDKTSPNGNDTSSVSGWGDPKPALRWGDSKGSNCQGGWED 806
TE GS T +G+ T +G T S++G K + ++ ++ +G
Sbjct: 666 TSTE--GSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEIT 723
Query: 807 DSAATGMVKSNQWGNCKEEKAAWNDSQKNKQGWGDGQKSSQGWSVS-----ASDNWGETS 861
++ TG + E A + + G +++ + S AS ET+
Sbjct: 724 TASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETT 783
Query: 862 RNNHWGEANKKSSSGGS--------DSDRSVSGWNELGKTSSFTWGNNINPNNSSGWDES 913
+ G K S+ S +S+ +++ T+ T G+ P +++G E+
Sbjct: 784 MASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAG-SET 842
Query: 914 SKPTPSQG 921
+ T ++G
Sbjct: 843 TTTTSTEG 850
Score = 72.4 bits (176), Expect = 4e-12
Identities = 120/584 (20%), Positives = 214/584 (36%), Gaps = 30/584 (5%)
Query: 201 STSGSHYENSQRGPVSSTSDSSTNCKNAVVSDLSEKEAWPSAPGSDPELASECMDADSAS 260
+T+GS + + +T+ S+T + V + S GS+ S +
Sbjct: 467 TTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTV 526
Query: 261 SSESERNITIMASGNTGGEKDGLRNSTGLGSQNKFVVGSSSNNVGHGSSTGPWGFSHGAI 320
S+E N T+ +T G + ++TGL + GS V + + G+
Sbjct: 527 STEGSENTTV----STTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGS- 581
Query: 321 ISTCQVSVDAPESKSESSNNRMNAWGTVSSSSNGGLNPSTLNSASNHGAWPVLENNGLAL 380
T S E+ + S+ + N T S++ + + ST S + + E +
Sbjct: 582 -GTTAASTAGSETTTVSTADSENT--TASTADSETTSASTTGSETTTASTTSSETTTAST 638
Query: 381 KGPVGSGSSGINIQCSTIGQMPNNQSINSKVSGGSTHGTWGSLQETCESEVSGTQKVSFS 440
+G + S + + + + + ++I S +T + + T +E SGT VS +
Sbjct: 639 EGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSIT 698
Query: 441 GQPQNITTEMTGPNNTTNFMTSSLPNSGSVQNNELPSSNTGAWRVSTMNHPQMQAPSGMN 500
G + TG TT S + S+ +E +++T +T + G
Sbjct: 699 GS-ETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTT------ASTEGSE 751
Query: 501 GTSLSHLSNGESKSGGSYGTTWGAYGSNYSGDKCSGPNGQANGDTVNATLMQPGVNGPMG 560
TS S + GS TT S + G + T + M
Sbjct: 752 TTSAS--------TTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMT 803
Query: 561 TNFQVNTNKGGGVWESGAANSQSTSWGSGNGANSGGSRRGWGTPAQNTGTNLPSVEWNKL 620
T F N+ + + ST+ A++ GS T + + T S E ++
Sbjct: 804 TVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE- 862
Query: 621 PSNQHSNDSANGNGKTFTNGWKSTEEEDQGSATSQTNEQSSVWAKTGGTVESDGSTESTG 680
+ S +S+ T T G ++T +GS T+ T+ + S T T S+ +T ST
Sbjct: 863 -TTTASTESSETTTAT-TIGSETTTASTEGSETTTTSTEGSE-TTTASTEGSEITTVSTT 919
Query: 681 RLEEKGTGESQSRDRRKIDQHTLLQSIVNRTDLDPRVLSNSGWGQTPIKQNTAWDTETSP 740
E T ++ + + V+ T + +S G T + + T S
Sbjct: 920 G-SETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTAST 978
Query: 741 RGERKTDNGTEAWGSSATQTFNSGACIDKTSPNGNDTSSVSGWG 784
G T T GS T G+ S G++T++VS G
Sbjct: 979 AGSETTTVSTA--GSETTTASIEGSETTTVSSTGSETTTVSTTG 1020
Score = 41.2 bits (95), Expect = 0.010
Identities = 89/471 (18%), Positives = 165/471 (35%), Gaps = 42/471 (8%)
Query: 152 GQHFPVIAANLGSAVKVLNSQSESSALTNQQPQNNGEVQNSKNQSDINHSTSGSHYENSQ 211
G ++ + V SE++ +T + ++ ST+GS +
Sbjct: 940 GSELTTVSTTGSETITVSAEGSETTTVTTMGSETT--TASTAGSETTTVSTAGSETTTAS 997
Query: 212 RGPVSSTSDSSTNCKNAVVSDLSEKEAWPSAPGSDPELASECMDADSASSSESERNITIM 271
+T+ SST + VS + S GS+ + +A + T
Sbjct: 998 IEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTT- 1056
Query: 272 ASGNTGGEKDGLRNSTGLGSQNKFVVGSSSNNVGHGSSTGPWGFSHGAIISTCQVSVDAP 331
+T G + ++TG + + V S + G+ +T ++
Sbjct: 1057 ---STEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYIT---- 1109
Query: 332 ESKSESSNNRMNAWGTVSSSSNGGLNPSTLNSASNHGAWPVLENNGLALKGPVGSGSSGI 391
SK+ +++ + TVS++S+ ST S V E ++ G + SS
Sbjct: 1110 GSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAA 1169
Query: 392 NIQCSTIGQMPNNQSINSKVSGGSTHGTWGSLQETCESEVSGTQKVSFSGQPQNITTEMT 451
+ +T +++ S +T T GS T + S T S SG N T T
Sbjct: 1170 GSEATT---------TSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETN-TACTT 1219
Query: 452 GPNNTTNFMTSSLPNSGSVQNNELPSSNTGAWRVSTMNHPQMQAPSGMNGTSLSHLSNGE 511
G +T S N+ + +E ++T + P + +G T++S ++G
Sbjct: 1220 GSETSTPSSAGSETNTAFIIGSETTIASTASL------EPTATSLTGSETTTVSITASGA 1273
Query: 512 SKSGGSYGTTWGAY------------GSNYSGDKCSGPNGQANGDTVNATLMQPGVNGPM 559
+ + + +T + SG + +G A+ A M +
Sbjct: 1274 TAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRPTASSSVTMAPGMDFTASAAS 1333
Query: 560 GTNFQVNTNKGG-GVWESGAANSQSTSWGSGNGANSGGSRRGWGTPAQNTG 609
T + N G G GA+ ST+ G +G +R + Q TG
Sbjct: 1334 HTVPGIVLNTSGLGTSTMGAS---STTSAHGVRTTTGSTREPTSSTFQETG 1381
Score = 37.0 bits (84), Expect = 0.19
Identities = 53/251 (21%), Positives = 91/251 (36%), Gaps = 20/251 (7%)
Query: 215 VSSTSDSSTNCKNAVVSDLSEKEAWP-SAPGSDPELASECMDADSASSSESERNITIMAS 273
VS T+ ST A S + EA S GS+ AS + +S+ T S
Sbjct: 1150 VSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTS 1209
Query: 274 GN------TGGEKDGLRNSTGLGSQNKFVVGSSSNNVGHGSSTGPWGFS-HGAIISTCQV 326
G+ T G + +S G + F++GS + + +S P S G+ +T +
Sbjct: 1210 GSETNTACTTGSETSTPSSAGSETNTAFIIGSETT-IASTASLEPTATSLTGSETTTVSI 1268
Query: 327 SVDAPESKSESSNNRMNAWGTVSSSSNGGLNPSTLNSASNHGAWPVLENNGLALKGPVGS 386
+ + S + ++ + S + + ++ G P ++ G +
Sbjct: 1269 TASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRPTASSSVTMAPGMDFT 1328
Query: 387 GSSGIN----IQCSTIGQMPNNQSINSKVSGGSTHGTWGSLQETCESEVS-------GTQ 435
S+ + I +T G + +S S T GS +E S GT
Sbjct: 1329 ASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREPTSSTFQETGPVSMGTN 1388
Query: 436 KVSFSGQPQNI 446
VS S P N+
Sbjct: 1389 TVSMSHTPTNV 1399
>gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1531
Score = 73.2 bits (178), Expect = 2e-12
Identities = 148/788 (18%), Positives = 274/788 (34%), Gaps = 100/788 (12%)
Query: 175 SSALTNQQPQNNGEVQNSKNQSDINHSTSGSHYENSQRGPVSSTSDSSTNCKNAVVSDLS 234
S TN + V ++ ST GS + +T+ S+T + V
Sbjct: 122 SETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAG 181
Query: 235 EKEAWPSAPGSDPELASECMDADSASSSESERNITIMASGNTGGEKDGLRNSTGLGSQNK 294
+ PS GS+ + S+ T+ +G+ + T S
Sbjct: 182 SETITPSTAGSE----------TTTVSTAGSETTTVSTTGSETTTASTAHSETTAAS--- 228
Query: 295 FVVGSSSNNVGHGSSTGPWGFSHGAIISTCQVSVDAPESKSESSNNRMNAWGTVSSSSNG 354
+GS + V S +ST A ++ +N +++S
Sbjct: 229 -TMGSETTKVSTAGSE--------TTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTT 279
Query: 355 GLNPSTLNSASNHGAWPVL------ENNGLALKGP----VGSGSSGI---------NIQC 395
G + +AS G+ P + E + GP V + SS + I+
Sbjct: 280 GFETT---AASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRA 336
Query: 396 STIG------QMPNNQSINSKVSGG--STHGTWGSLQETCESEVSGTQKVSFSGQPQNIT 447
ST+G +++ + + G ST T GS T +E S T S G + T
Sbjct: 337 STVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGS-EATT 395
Query: 448 TEMTGPNNTTNFMTSSLPNSGSVQNNELPSSNTGAWRVSTMNHPQMQAPSGMNGTSLSHL 507
TG TT +T S + + +E+ + +T + +T + G+ ++
Sbjct: 396 VSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTT---------ASTEGSEITIA 446
Query: 508 SNGESKSGGSYGTTWGAYGSNYSGDKCSGPNGQANGDTVNATLMQPGVNGPMGTNFQVNT 567
S +S++ TT GS + +G + T + T T F + +
Sbjct: 447 STSDSET-----TTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGS 501
Query: 568 NKGGGVWESGAANSQSTSWGSGNGANSGGSRRGWGTPAQNTGTNLPSVEWNKLPSNQHSN 627
+ E + S + ++ GS T TG+ +V L + S
Sbjct: 502 DTTTASTEGSETTAVSATGSEMTTVSTEGSE---NTTVSTTGSETTTVSTTGLETTTTST 558
Query: 628 DSANGNGKTFTNGWKSTEEEDQGSATSQTNEQSSVWAKTGGTVESDGSTESTGRLEEKGT 687
+ + T G ++T + +GS T+ + S T T +S+ +T ST E
Sbjct: 559 EGSEMT-TVSTTGAETTTDSTEGSGTTAASTAGSE-TTTVSTADSENTTASTADSETTSA 616
Query: 688 GESQSRDRRKIDQHTLLQSIVNRTDLDPRVLSNSGWGQTPIKQNTAWDTETSPRGERKTD 747
+ S + + T + S G T + + T S G +T
Sbjct: 617 STTGSE-----------TTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665
Query: 748 NGTEAWGSSATQTFNSGA-CIDKTSPNGNDTSSVSGWGDPKPALRWGDSKGSNCQGGWED 806
TE GS T +G+ T +G T S++G K + ++ ++ +G
Sbjct: 666 TSTE--GSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEIT 723
Query: 807 DSAATGMVKSNQWGNCKEEKAAWNDSQKNKQGWGDGQKSSQGWSVS-----ASDNWGETS 861
++ TG + E A + + G +++ + S AS ET+
Sbjct: 724 TASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETT 783
Query: 862 RNNHWGEANKKSSSGGS--------DSDRSVSGWNELGKTSSFTWGNNINPNNSSGWDES 913
+ G K S+ S +S+ +++ T+ T G+ P +++G E+
Sbjct: 784 MASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAG-SET 842
Query: 914 SKPTPSQG 921
+ T ++G
Sbjct: 843 TTTTSTEG 850
Score = 72.4 bits (176), Expect = 4e-12
Identities = 120/584 (20%), Positives = 214/584 (36%), Gaps = 30/584 (5%)
Query: 201 STSGSHYENSQRGPVSSTSDSSTNCKNAVVSDLSEKEAWPSAPGSDPELASECMDADSAS 260
+T+GS + + +T+ S+T + V + S GS+ S +
Sbjct: 467 TTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTV 526
Query: 261 SSESERNITIMASGNTGGEKDGLRNSTGLGSQNKFVVGSSSNNVGHGSSTGPWGFSHGAI 320
S+E N T+ +T G + ++TGL + GS V + + G+
Sbjct: 527 STEGSENTTV----STTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGS- 581
Query: 321 ISTCQVSVDAPESKSESSNNRMNAWGTVSSSSNGGLNPSTLNSASNHGAWPVLENNGLAL 380
T S E+ + S+ + N T S++ + + ST S + + E +
Sbjct: 582 -GTTAASTAGSETTTVSTADSENT--TASTADSETTSASTTGSETTTASTTSSETTTAST 638
Query: 381 KGPVGSGSSGINIQCSTIGQMPNNQSINSKVSGGSTHGTWGSLQETCESEVSGTQKVSFS 440
+G + S + + + + + ++I S +T + + T +E SGT VS +
Sbjct: 639 EGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSIT 698
Query: 441 GQPQNITTEMTGPNNTTNFMTSSLPNSGSVQNNELPSSNTGAWRVSTMNHPQMQAPSGMN 500
G + TG TT S + S+ +E +++T +T + G
Sbjct: 699 GS-ETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTT------ASTEGSE 751
Query: 501 GTSLSHLSNGESKSGGSYGTTWGAYGSNYSGDKCSGPNGQANGDTVNATLMQPGVNGPMG 560
TS S + GS TT S + G + T + M
Sbjct: 752 TTSAS--------TTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMT 803
Query: 561 TNFQVNTNKGGGVWESGAANSQSTSWGSGNGANSGGSRRGWGTPAQNTGTNLPSVEWNKL 620
T F N+ + + ST+ A++ GS T + + T S E ++
Sbjct: 804 TVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE- 862
Query: 621 PSNQHSNDSANGNGKTFTNGWKSTEEEDQGSATSQTNEQSSVWAKTGGTVESDGSTESTG 680
+ S +S+ T T G ++T +GS T+ T+ + S T T S+ +T ST
Sbjct: 863 -TTTASTESSETTTAT-TIGSETTTASTEGSETTTTSTEGSE-TTTASTEGSEITTVSTT 919
Query: 681 RLEEKGTGESQSRDRRKIDQHTLLQSIVNRTDLDPRVLSNSGWGQTPIKQNTAWDTETSP 740
E T ++ + + V+ T + +S G T + + T S
Sbjct: 920 G-SETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTAST 978
Query: 741 RGERKTDNGTEAWGSSATQTFNSGACIDKTSPNGNDTSSVSGWG 784
G T T GS T G+ S G++T++VS G
Sbjct: 979 AGSETTTVSTA--GSETTTASIEGSETTTVSSTGSETTTVSTTG 1020
Score = 42.0 bits (97), Expect = 0.006
Identities = 70/371 (18%), Positives = 134/371 (36%), Gaps = 18/371 (4%)
Query: 152 GQHFPVIAANLGSAVKVLNSQSESSALTNQQPQNNGEVQNSKNQSDINHSTSGSHYENSQ 211
G ++ + V SE++ +T + ++ ST+GS +
Sbjct: 940 GSELTTVSTTGSETITVSAEGSETTTVTTMGSETT--TASTAGSETTTVSTAGSETTTAS 997
Query: 212 RGPVSSTSDSSTNCKNAVVSDLSEKEAWPSAPGSDPELASECMDADSASSSESERNITIM 271
+T+ SST + VS + S GS+ + +A + T
Sbjct: 998 IEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTT- 1056
Query: 272 ASGNTGGEKDGLRNSTGLGSQNKFVVGSSSNNVGHGSSTGPWGFSHGAIISTCQVSVDAP 331
+T G + ++TG + + V S + G+ +T ++
Sbjct: 1057 ---STEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYIT---- 1109
Query: 332 ESKSESSNNRMNAWGTVSSSSNGGLNPSTLNSASNHGAWPVLENNGLALKGPVGSGSSGI 391
SK+ +++ + TVS++S+ ST S V E ++ G + SS
Sbjct: 1110 GSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAA 1169
Query: 392 NIQCSTIGQMPNNQSINSKV-SGGSTHGTWGSLQETCESEVSGTQKVSFSGQPQNITTEM 450
+ +T + + S S +T T GS T + S T S SG N T
Sbjct: 1170 GSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETN-TACT 1228
Query: 451 TGPNNTTNFMTSSLPNSGSVQNNELPSSNTGAWRVSTMNHPQMQAPSGMNGTSLSHLSNG 510
TG +T S N+ + +E ++T + P + +G T++S ++G
Sbjct: 1229 TGSETSTPSSAGSETNTAFIIGSETTIASTASL------EPTATSLTGSETTTVSITASG 1282
Query: 511 ESKSGGSYGTT 521
+ + + +T
Sbjct: 1283 ATAASTTVSST 1293
Score = 32.0 bits (71), Expect = 6.1
Identities = 53/281 (18%), Positives = 101/281 (35%), Gaps = 41/281 (14%)
Query: 170 NSQSESSALTNQQPQNNGEVQNSKNQSDINHSTSGSHYENSQRGPVSSTSDSSTNCKNAV 229
+S + S A T + ++ ST+GS + +T+ S++ +
Sbjct: 1166 SSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNT 1225
Query: 230 VSDLSEKEAWPSAPGSDPELA----SECMDADSASSSESERNITIMASGNTGGEKDGLRN 285
+ + PS+ GS+ A SE A +AS + ++T + G
Sbjct: 1226 ACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATA 1285
Query: 286 STGLGSQNKFVVGSSSNNVGHGSSTGPWGFSHGAIISTCQVSVDAPESKSESSNNRMNAW 345
++ S FV+ +++ + Q + P S + ++ R+ A
Sbjct: 1286 ASTTVSSTTFVLTKATD-------------------VSIQPITNTPMSGTRTTGTRLTAS 1326
Query: 346 GTVSSSSNGGLNPSTLNSASNHGAWPVLENNGLALKGPVGSGSSGINIQCSTIGQMPNNQ 405
+V+ + G++ T ++AS+ VL +GL ST+G
Sbjct: 1327 SSVTMAP--GMD-FTASAASHTVPGIVLNTSGLG---------------TSTMGASSTTS 1368
Query: 406 SINSKVSGGSTHGTWGSLQETCESEVSGTQKVSFSGQPQNI 446
+ + + GST S + GT VS S P N+
Sbjct: 1369 AHGVRTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTNV 1409
>gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1531
Score = 73.2 bits (178), Expect = 2e-12
Identities = 148/788 (18%), Positives = 274/788 (34%), Gaps = 100/788 (12%)
Query: 175 SSALTNQQPQNNGEVQNSKNQSDINHSTSGSHYENSQRGPVSSTSDSSTNCKNAVVSDLS 234
S TN + V ++ ST GS + +T+ S+T + V
Sbjct: 122 SETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAG 181
Query: 235 EKEAWPSAPGSDPELASECMDADSASSSESERNITIMASGNTGGEKDGLRNSTGLGSQNK 294
+ PS GS+ + S+ T+ +G+ + T S
Sbjct: 182 SETITPSTAGSE----------TTTVSTAGSETTTVSTTGSETTTASTAHSETTAAS--- 228
Query: 295 FVVGSSSNNVGHGSSTGPWGFSHGAIISTCQVSVDAPESKSESSNNRMNAWGTVSSSSNG 354
+GS + V S +ST A ++ +N +++S
Sbjct: 229 -TMGSETTKVSTAGSE--------TTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTT 279
Query: 355 GLNPSTLNSASNHGAWPVL------ENNGLALKGP----VGSGSSGI---------NIQC 395
G + +AS G+ P + E + GP V + SS + I+
Sbjct: 280 GFETT---AASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRA 336
Query: 396 STIG------QMPNNQSINSKVSGG--STHGTWGSLQETCESEVSGTQKVSFSGQPQNIT 447
ST+G +++ + + G ST T GS T +E S T S G + T
Sbjct: 337 STVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGS-EATT 395
Query: 448 TEMTGPNNTTNFMTSSLPNSGSVQNNELPSSNTGAWRVSTMNHPQMQAPSGMNGTSLSHL 507
TG TT +T S + + +E+ + +T + +T + G+ ++
Sbjct: 396 VSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTT---------ASTEGSEITIA 446
Query: 508 SNGESKSGGSYGTTWGAYGSNYSGDKCSGPNGQANGDTVNATLMQPGVNGPMGTNFQVNT 567
S +S++ TT GS + +G + T + T T F + +
Sbjct: 447 STSDSET-----TTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGS 501
Query: 568 NKGGGVWESGAANSQSTSWGSGNGANSGGSRRGWGTPAQNTGTNLPSVEWNKLPSNQHSN 627
+ E + S + ++ GS T TG+ +V L + S
Sbjct: 502 DTTTASTEGSETTAVSATGSEMTTVSTEGSE---NTTVSTTGSETTTVSTTGLETTTTST 558
Query: 628 DSANGNGKTFTNGWKSTEEEDQGSATSQTNEQSSVWAKTGGTVESDGSTESTGRLEEKGT 687
+ + T G ++T + +GS T+ + S T T +S+ +T ST E
Sbjct: 559 EGSEMT-TVSTTGAETTTDSTEGSGTTAASTAGSE-TTTVSTADSENTTASTADSETTSA 616
Query: 688 GESQSRDRRKIDQHTLLQSIVNRTDLDPRVLSNSGWGQTPIKQNTAWDTETSPRGERKTD 747
+ S + + T + S G T + + T S G +T
Sbjct: 617 STTGSE-----------TTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665
Query: 748 NGTEAWGSSATQTFNSGA-CIDKTSPNGNDTSSVSGWGDPKPALRWGDSKGSNCQGGWED 806
TE GS T +G+ T +G T S++G K + ++ ++ +G
Sbjct: 666 TSTE--GSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEIT 723
Query: 807 DSAATGMVKSNQWGNCKEEKAAWNDSQKNKQGWGDGQKSSQGWSVS-----ASDNWGETS 861
++ TG + E A + + G +++ + S AS ET+
Sbjct: 724 TASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETT 783
Query: 862 RNNHWGEANKKSSSGGS--------DSDRSVSGWNELGKTSSFTWGNNINPNNSSGWDES 913
+ G K S+ S +S+ +++ T+ T G+ P +++G E+
Sbjct: 784 MASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAG-SET 842
Query: 914 SKPTPSQG 921
+ T ++G
Sbjct: 843 TTTTSTEG 850
Score = 72.4 bits (176), Expect = 4e-12
Identities = 120/584 (20%), Positives = 214/584 (36%), Gaps = 30/584 (5%)
Query: 201 STSGSHYENSQRGPVSSTSDSSTNCKNAVVSDLSEKEAWPSAPGSDPELASECMDADSAS 260
+T+GS + + +T+ S+T + V + S GS+ S +
Sbjct: 467 TTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTV 526
Query: 261 SSESERNITIMASGNTGGEKDGLRNSTGLGSQNKFVVGSSSNNVGHGSSTGPWGFSHGAI 320
S+E N T+ +T G + ++TGL + GS V + + G+
Sbjct: 527 STEGSENTTV----STTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGS- 581
Query: 321 ISTCQVSVDAPESKSESSNNRMNAWGTVSSSSNGGLNPSTLNSASNHGAWPVLENNGLAL 380
T S E+ + S+ + N T S++ + + ST S + + E +
Sbjct: 582 -GTTAASTAGSETTTVSTADSENT--TASTADSETTSASTTGSETTTASTTSSETTTAST 638
Query: 381 KGPVGSGSSGINIQCSTIGQMPNNQSINSKVSGGSTHGTWGSLQETCESEVSGTQKVSFS 440
+G + S + + + + + ++I S +T + + T +E SGT VS +
Sbjct: 639 EGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSIT 698
Query: 441 GQPQNITTEMTGPNNTTNFMTSSLPNSGSVQNNELPSSNTGAWRVSTMNHPQMQAPSGMN 500
G + TG TT S + S+ +E +++T +T + G
Sbjct: 699 GS-ETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTT------ASTEGSE 751
Query: 501 GTSLSHLSNGESKSGGSYGTTWGAYGSNYSGDKCSGPNGQANGDTVNATLMQPGVNGPMG 560
TS S + GS TT S + G + T + M
Sbjct: 752 TTSAS--------TTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMT 803
Query: 561 TNFQVNTNKGGGVWESGAANSQSTSWGSGNGANSGGSRRGWGTPAQNTGTNLPSVEWNKL 620
T F N+ + + ST+ A++ GS T + + T S E ++
Sbjct: 804 TVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE- 862
Query: 621 PSNQHSNDSANGNGKTFTNGWKSTEEEDQGSATSQTNEQSSVWAKTGGTVESDGSTESTG 680
+ S +S+ T T G ++T +GS T+ T+ + S T T S+ +T ST
Sbjct: 863 -TTTASTESSETTTAT-TIGSETTTASTEGSETTTTSTEGSE-TTTASTEGSEITTVSTT 919
Query: 681 RLEEKGTGESQSRDRRKIDQHTLLQSIVNRTDLDPRVLSNSGWGQTPIKQNTAWDTETSP 740
E T ++ + + V+ T + +S G T + + T S
Sbjct: 920 G-SETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTAST 978
Query: 741 RGERKTDNGTEAWGSSATQTFNSGACIDKTSPNGNDTSSVSGWG 784
G T T GS T G+ S G++T++VS G
Sbjct: 979 AGSETTTVSTA--GSETTTASIEGSETTTVSSTGSETTTVSTTG 1020
Score = 42.0 bits (97), Expect = 0.006
Identities = 70/371 (18%), Positives = 134/371 (36%), Gaps = 18/371 (4%)
Query: 152 GQHFPVIAANLGSAVKVLNSQSESSALTNQQPQNNGEVQNSKNQSDINHSTSGSHYENSQ 211
G ++ + V SE++ +T + ++ ST+GS +
Sbjct: 940 GSELTTVSTTGSETITVSAEGSETTTVTTMGSETT--TASTAGSETTTVSTAGSETTTAS 997
Query: 212 RGPVSSTSDSSTNCKNAVVSDLSEKEAWPSAPGSDPELASECMDADSASSSESERNITIM 271
+T+ SST + VS + S GS+ + +A + T
Sbjct: 998 IEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTT- 1056
Query: 272 ASGNTGGEKDGLRNSTGLGSQNKFVVGSSSNNVGHGSSTGPWGFSHGAIISTCQVSVDAP 331
+T G + ++TG + + V S + G+ +T ++
Sbjct: 1057 ---STEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYIT---- 1109
Query: 332 ESKSESSNNRMNAWGTVSSSSNGGLNPSTLNSASNHGAWPVLENNGLALKGPVGSGSSGI 391
SK+ +++ + TVS++S+ ST S V E ++ G + SS
Sbjct: 1110 GSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAA 1169
Query: 392 NIQCSTIGQMPNNQSINSKV-SGGSTHGTWGSLQETCESEVSGTQKVSFSGQPQNITTEM 450
+ +T + + S S +T T GS T + S T S SG N T
Sbjct: 1170 GSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETN-TACT 1228
Query: 451 TGPNNTTNFMTSSLPNSGSVQNNELPSSNTGAWRVSTMNHPQMQAPSGMNGTSLSHLSNG 510
TG +T S N+ + +E ++T + P + +G T++S ++G
Sbjct: 1229 TGSETSTPSSAGSETNTAFIIGSETTIASTASL------EPTATSLTGSETTTVSITASG 1282
Query: 511 ESKSGGSYGTT 521
+ + + +T
Sbjct: 1283 ATAASTTVSST 1293
Score = 32.0 bits (71), Expect = 6.1
Identities = 53/281 (18%), Positives = 101/281 (35%), Gaps = 41/281 (14%)
Query: 170 NSQSESSALTNQQPQNNGEVQNSKNQSDINHSTSGSHYENSQRGPVSSTSDSSTNCKNAV 229
+S + S A T + ++ ST+GS + +T+ S++ +
Sbjct: 1166 SSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNT 1225
Query: 230 VSDLSEKEAWPSAPGSDPELA----SECMDADSASSSESERNITIMASGNTGGEKDGLRN 285
+ + PS+ GS+ A SE A +AS + ++T + G
Sbjct: 1226 ACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATA 1285
Query: 286 STGLGSQNKFVVGSSSNNVGHGSSTGPWGFSHGAIISTCQVSVDAPESKSESSNNRMNAW 345
++ S FV+ +++ + Q + P S + ++ R+ A
Sbjct: 1286 ASTTVSSTTFVLTKATD-------------------VSIQPITNTPMSGTRTTGTRLTAS 1326
Query: 346 GTVSSSSNGGLNPSTLNSASNHGAWPVLENNGLALKGPVGSGSSGINIQCSTIGQMPNNQ 405
+V+ + G++ T ++AS+ VL +GL ST+G
Sbjct: 1327 SSVTMAP--GMD-FTASAASHTVPGIVLNTSGLG---------------TSTMGASSTTS 1368
Query: 406 SINSKVSGGSTHGTWGSLQETCESEVSGTQKVSFSGQPQNI 446
+ + + GST S + GT VS S P N+
Sbjct: 1369 AHGVRTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTNV 1409
>gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1521
Score = 73.2 bits (178), Expect = 2e-12
Identities = 148/788 (18%), Positives = 274/788 (34%), Gaps = 100/788 (12%)
Query: 175 SSALTNQQPQNNGEVQNSKNQSDINHSTSGSHYENSQRGPVSSTSDSSTNCKNAVVSDLS 234
S TN + V ++ ST GS + +T+ S+T + V
Sbjct: 122 SETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAG 181
Query: 235 EKEAWPSAPGSDPELASECMDADSASSSESERNITIMASGNTGGEKDGLRNSTGLGSQNK 294
+ PS GS+ + S+ T+ +G+ + T S
Sbjct: 182 SETITPSTAGSE----------TTTVSTAGSETTTVSTTGSETTTASTAHSETTAAS--- 228
Query: 295 FVVGSSSNNVGHGSSTGPWGFSHGAIISTCQVSVDAPESKSESSNNRMNAWGTVSSSSNG 354
+GS + V S +ST A ++ +N +++S
Sbjct: 229 -TMGSETTKVSTAGSE--------TTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTT 279
Query: 355 GLNPSTLNSASNHGAWPVL------ENNGLALKGP----VGSGSSGI---------NIQC 395
G + +AS G+ P + E + GP V + SS + I+
Sbjct: 280 GFETT---AASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRA 336
Query: 396 STIG------QMPNNQSINSKVSGG--STHGTWGSLQETCESEVSGTQKVSFSGQPQNIT 447
ST+G +++ + + G ST T GS T +E S T S G + T
Sbjct: 337 STVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGS-EATT 395
Query: 448 TEMTGPNNTTNFMTSSLPNSGSVQNNELPSSNTGAWRVSTMNHPQMQAPSGMNGTSLSHL 507
TG TT +T S + + +E+ + +T + +T + G+ ++
Sbjct: 396 VSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTT---------ASTEGSEITIA 446
Query: 508 SNGESKSGGSYGTTWGAYGSNYSGDKCSGPNGQANGDTVNATLMQPGVNGPMGTNFQVNT 567
S +S++ TT GS + +G + T + T T F + +
Sbjct: 447 STSDSET-----TTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGS 501
Query: 568 NKGGGVWESGAANSQSTSWGSGNGANSGGSRRGWGTPAQNTGTNLPSVEWNKLPSNQHSN 627
+ E + S + ++ GS T TG+ +V L + S
Sbjct: 502 DTTTASTEGSETTAVSATGSEMTTVSTEGSE---NTTVSTTGSETTTVSTTGLETTTTST 558
Query: 628 DSANGNGKTFTNGWKSTEEEDQGSATSQTNEQSSVWAKTGGTVESDGSTESTGRLEEKGT 687
+ + T G ++T + +GS T+ + S T T +S+ +T ST E
Sbjct: 559 EGSEMT-TVSTTGAETTTDSTEGSGTTAASTAGSE-TTTVSTADSENTTASTADSETTSA 616
Query: 688 GESQSRDRRKIDQHTLLQSIVNRTDLDPRVLSNSGWGQTPIKQNTAWDTETSPRGERKTD 747
+ S + + T + S G T + + T S G +T
Sbjct: 617 STTGSE-----------TTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665
Query: 748 NGTEAWGSSATQTFNSGA-CIDKTSPNGNDTSSVSGWGDPKPALRWGDSKGSNCQGGWED 806
TE GS T +G+ T +G T S++G K + ++ ++ +G
Sbjct: 666 TSTE--GSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEIT 723
Query: 807 DSAATGMVKSNQWGNCKEEKAAWNDSQKNKQGWGDGQKSSQGWSVS-----ASDNWGETS 861
++ TG + E A + + G +++ + S AS ET+
Sbjct: 724 TASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETT 783
Query: 862 RNNHWGEANKKSSSGGS--------DSDRSVSGWNELGKTSSFTWGNNINPNNSSGWDES 913
+ G K S+ S +S+ +++ T+ T G+ P +++G E+
Sbjct: 784 MASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAG-SET 842
Query: 914 SKPTPSQG 921
+ T ++G
Sbjct: 843 TTTTSTEG 850
Score = 72.4 bits (176), Expect = 4e-12
Identities = 120/584 (20%), Positives = 214/584 (36%), Gaps = 30/584 (5%)
Query: 201 STSGSHYENSQRGPVSSTSDSSTNCKNAVVSDLSEKEAWPSAPGSDPELASECMDADSAS 260
+T+GS + + +T+ S+T + V + S GS+ S +
Sbjct: 467 TTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTV 526
Query: 261 SSESERNITIMASGNTGGEKDGLRNSTGLGSQNKFVVGSSSNNVGHGSSTGPWGFSHGAI 320
S+E N T+ +T G + ++TGL + GS V + + G+
Sbjct: 527 STEGSENTTV----STTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGS- 581
Query: 321 ISTCQVSVDAPESKSESSNNRMNAWGTVSSSSNGGLNPSTLNSASNHGAWPVLENNGLAL 380
T S E+ + S+ + N T S++ + + ST S + + E +
Sbjct: 582 -GTTAASTAGSETTTVSTADSENT--TASTADSETTSASTTGSETTTASTTSSETTTAST 638
Query: 381 KGPVGSGSSGINIQCSTIGQMPNNQSINSKVSGGSTHGTWGSLQETCESEVSGTQKVSFS 440
+G + S + + + + + ++I S +T + + T +E SGT VS +
Sbjct: 639 EGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSIT 698
Query: 441 GQPQNITTEMTGPNNTTNFMTSSLPNSGSVQNNELPSSNTGAWRVSTMNHPQMQAPSGMN 500
G + TG TT S + S+ +E +++T +T + G
Sbjct: 699 GS-ETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTT------ASTEGSE 751
Query: 501 GTSLSHLSNGESKSGGSYGTTWGAYGSNYSGDKCSGPNGQANGDTVNATLMQPGVNGPMG 560
TS S + GS TT S + G + T + M
Sbjct: 752 TTSAS--------TTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMT 803
Query: 561 TNFQVNTNKGGGVWESGAANSQSTSWGSGNGANSGGSRRGWGTPAQNTGTNLPSVEWNKL 620
T F N+ + + ST+ A++ GS T + + T S E ++
Sbjct: 804 TVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE- 862
Query: 621 PSNQHSNDSANGNGKTFTNGWKSTEEEDQGSATSQTNEQSSVWAKTGGTVESDGSTESTG 680
+ S +S+ T T G ++T +GS T+ T+ + S T T S+ +T ST
Sbjct: 863 -TTTASTESSETTTAT-TIGSETTTASTEGSETTTTSTEGSE-TTTASTEGSEITTVSTT 919
Query: 681 RLEEKGTGESQSRDRRKIDQHTLLQSIVNRTDLDPRVLSNSGWGQTPIKQNTAWDTETSP 740
E T ++ + + V+ T + +S G T + + T S
Sbjct: 920 G-SETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTAST 978
Query: 741 RGERKTDNGTEAWGSSATQTFNSGACIDKTSPNGNDTSSVSGWG 784
G T T GS T G+ S G++T++VS G
Sbjct: 979 AGSETTTVSTA--GSETTTASIEGSETTTVSSTGSETTTVSTTG 1020
Score = 41.6 bits (96), Expect = 0.008
Identities = 82/454 (18%), Positives = 153/454 (33%), Gaps = 48/454 (10%)
Query: 152 GQHFPVIAANLGSAVKVLNSQSESSALTNQQPQNNGEVQNSKNQSDINHSTSGSHYENSQ 211
G ++ + V SE++ +T + ++ ST+GS +
Sbjct: 940 GSELTTVSTTGSETITVSAEGSETTTVTTMGSETT--TASTAGSETTTVSTAGSETTTAS 997
Query: 212 RGPVSSTSDSSTNCKNAVVSDLSEKEAWPSAPGSDPELASECMDADSA----------SS 261
+T+ SST + VS + S GS+ + +A +S
Sbjct: 998 IEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTS 1057
Query: 262 SESERNITIMASG------NTGGEKDGLRNSTGLGSQNKFVVGSSSNNVGHGSSTGPWGF 315
+E T+ +G +T + +++G G+ GS + V S
Sbjct: 1058 TEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTAS 1117
Query: 316 SHGAIISTCQVSVDAPESKSESSNNRMNAWGTVSSS---SNGGLNPSTLNSASNHGAWPV 372
+ G+ +T + + S + + + TVS + S G +T ++A +
Sbjct: 1118 TEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTS 1177
Query: 373 LENNGLALKGPVGS-----------------GSSGINIQCSTIGQMPNNQSINSK----- 410
E + GS S N C+T + S S+
Sbjct: 1178 TEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAF 1237
Query: 411 -VSGGSTHGTWGSLQETCESEVSGTQKVSFSGQPQNITTEMTGPNNTTNFMTSSLPNS-G 468
+ ST + SL+ T S ++G++ + S T T ++TT +T + S
Sbjct: 1238 IIGSESTIASTASLEPTATS-LTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQ 1296
Query: 469 SVQNNELPSSNTGAWRVSTMNHPQMQAPSGMNGTSLSHLSNGESKSGGSYGTTWGAYGSN 528
+ N + + T R++ + M ++ SH G + GT+ S
Sbjct: 1297 PITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASST 1356
Query: 529 YSGDKCSGPNGQANGDTVNATLMQPGVNGPMGTN 562
S G T ++T + G MGTN
Sbjct: 1357 TSAHGVRTTTGSTREPT-SSTFQETGPVS-MGTN 1388
Score = 32.7 bits (73), Expect = 3.6
Identities = 52/276 (18%), Positives = 100/276 (36%), Gaps = 41/276 (14%)
Query: 175 SSALTNQQPQNNGEVQNSKNQSDINHSTSGSHYENSQRGPVSSTSDSSTNCKNAVVSDLS 234
S A T+ + +++ ST+GS + +T+ S++ +
Sbjct: 1161 SEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTG 1220
Query: 235 EKEAWPSAPGSDPELA----SECMDADSASSSESERNITIMASGNTGGEKDGLRNSTGLG 290
+ + PS+ GS+ A SE A +AS + ++T + G ++
Sbjct: 1221 SETSTPSSAGSETNTAFIIGSESTIASTASLEPTATSLTGSETTTVSITASGATAASTTV 1280
Query: 291 SQNKFVVGSSSNNVGHGSSTGPWGFSHGAIISTCQVSVDAPESKSESSNNRMNAWGTVSS 350
S FV+ +++ + Q + P S + ++ R+ A +V+
Sbjct: 1281 SSTTFVLTKATD-------------------VSIQPITNTPMSGTRTTGTRLTASSSVTM 1321
Query: 351 SSNGGLNPSTLNSASNHGAWPVLENNGLALKGPVGSGSSGINIQCSTIGQMPNNQSINSK 410
+ G++ T ++AS+ VL +GL ST+G + +
Sbjct: 1322 AP--GMD-FTASAASHTVPGIVLNTSGLG---------------TSTMGASSTTSAHGVR 1363
Query: 411 VSGGSTHGTWGSLQETCESEVSGTQKVSFSGQPQNI 446
+ GST S + GT VS S P N+
Sbjct: 1364 TTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTNV 1399
>gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo
sapiens]
Length = 1521
Score = 72.4 bits (176), Expect = 4e-12
Identities = 148/788 (18%), Positives = 274/788 (34%), Gaps = 100/788 (12%)
Query: 175 SSALTNQQPQNNGEVQNSKNQSDINHSTSGSHYENSQRGPVSSTSDSSTNCKNAVVSDLS 234
S TN + V ++ ST GS + +T+ S+T + V
Sbjct: 122 SETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAG 181
Query: 235 EKEAWPSAPGSDPELASECMDADSASSSESERNITIMASGNTGGEKDGLRNSTGLGSQNK 294
+ PS GS+ + S+ T+ +G+ + T S
Sbjct: 182 SETITPSTAGSE----------TTTVSTAGSETTTVSTTGSETTTASTAHSETTAAS--- 228
Query: 295 FVVGSSSNNVGHGSSTGPWGFSHGAIISTCQVSVDAPESKSESSNNRMNAWGTVSSSSNG 354
+GS + V S +ST A ++ +N +++S
Sbjct: 229 -TMGSETTKVSTAGSE--------TTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTT 279
Query: 355 GLNPSTLNSASNHGAWPVL------ENNGLALKGP----VGSGSSGI---------NIQC 395
G + +AS G+ P + E + GP V + SS + I+
Sbjct: 280 GFETT---AASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRA 336
Query: 396 STIG------QMPNNQSINSKVSGG--STHGTWGSLQETCESEVSGTQKVSFSGQPQNIT 447
ST+G +++ + + G ST T GS T +E S T S G + T
Sbjct: 337 STVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGS-EATT 395
Query: 448 TEMTGPNNTTNFMTSSLPNSGSVQNNELPSSNTGAWRVSTMNHPQMQAPSGMNGTSLSHL 507
TG TT +T S + + +E+ + +T + +T + G+ ++
Sbjct: 396 VSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTT---------ASTEGSEITIA 446
Query: 508 SNGESKSGGSYGTTWGAYGSNYSGDKCSGPNGQANGDTVNATLMQPGVNGPMGTNFQVNT 567
S +S++ TT GS + +G + T + T T F + +
Sbjct: 447 STSDSET-----TTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGS 501
Query: 568 NKGGGVWESGAANSQSTSWGSGNGANSGGSRRGWGTPAQNTGTNLPSVEWNKLPSNQHSN 627
+ E + S + ++ GS T TG+ +V L + S
Sbjct: 502 DTTTASTEGSETTAVSATGSEMTTVSTEGSE---NTTVSTTGSETTTVSTTGLETTTTST 558
Query: 628 DSANGNGKTFTNGWKSTEEEDQGSATSQTNEQSSVWAKTGGTVESDGSTESTGRLEEKGT 687
+ + T G ++T + +GS T+ + S T T +S+ +T ST E
Sbjct: 559 EGSEMT-TVSTTGAETTTDSTEGSGTTAASTAGSE-TTTVSTADSENTTASTADSETTSA 616
Query: 688 GESQSRDRRKIDQHTLLQSIVNRTDLDPRVLSNSGWGQTPIKQNTAWDTETSPRGERKTD 747
+ S + + T + S G T + + T S G +T
Sbjct: 617 STTGSE-----------TTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665
Query: 748 NGTEAWGSSATQTFNSGA-CIDKTSPNGNDTSSVSGWGDPKPALRWGDSKGSNCQGGWED 806
TE GS T +G+ T +G T S++G K + ++ ++ +G
Sbjct: 666 TSTE--GSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTITSTEGSEIT 723
Query: 807 DSAATGMVKSNQWGNCKEEKAAWNDSQKNKQGWGDGQKSSQGWSVS-----ASDNWGETS 861
++ TG + E A + + G +++ + S AS ET+
Sbjct: 724 TASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETT 783
Query: 862 RNNHWGEANKKSSSGGS--------DSDRSVSGWNELGKTSSFTWGNNINPNNSSGWDES 913
+ G K S+ S +S+ +++ T+ T G+ P +++G E+
Sbjct: 784 MASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAG-SET 842
Query: 914 SKPTPSQG 921
+ T ++G
Sbjct: 843 TTTTSTEG 850
Score = 62.4 bits (150), Expect = 4e-09
Identities = 114/598 (19%), Positives = 220/598 (36%), Gaps = 48/598 (8%)
Query: 201 STSGSHYENSQRGPVSSTSDSSTNCKNAVVSDLSEKEAWPSAPGSDPELASECMDADSAS 260
ST+GS +T+ + + VS + S GS+ +AS + +
Sbjct: 397 STTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTA 456
Query: 261 SSESERNITIMASGN------TGGEKDGLRNSTGLGSQNKFVVGSSSNNVGHGSSTGPWG 314
S+E T+ +G+ T G + ++TGL + F +GS + S
Sbjct: 457 STEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAV 516
Query: 315 FSHGAIISTCQV--SVDAPESKSESSNNRMNAWGT-VSSSSNGGLNPSTLNSASNHGAWP 371
+ G+ ++T S + S + S ++ G +++S G +T+++
Sbjct: 517 SATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTD 576
Query: 372 VLENNGLALKGPVGSGSSGINIQCSTIGQMPNNQSINSKVSGGSTHGTWGSLQETCESEV 431
E +G GS ++ ++ S + + +S+ + ST G+ ET +
Sbjct: 577 STEGSGTTAASTAGSETTTVSTADS---ENTTASTADSETTSASTTGS-----ETTTAST 628
Query: 432 SGTQKVSFSGQPQNITTEMTGPNNTTNFMTSSLPNSGSVQNNELPSSNTGAWRVSTMNHP 491
+ ++ + S + TT T + TT M S+ + ++ + E + T VS
Sbjct: 629 TSSETTTASTEGSETTTVSTTDSETT--MVSTTGSERTITSTEGSETTT----VSATGSE 682
Query: 492 QMQAPSGMNGTSLSHLSNGESK--SGGSYGTTWGAYGSNYSGDKCSGPNGQANGDTVNAT 549
+ G T++S + +K + GS T GS + +G +T A+
Sbjct: 683 TTVSTEGSGTTTVSITGSETTKVSTTGSETTITSTEGSEITTASITG------SETTTAS 736
Query: 550 LMQPGVNGPMGTNFQVNTNKGGGVWESGAANSQSTSWGSGNGANSGGSRRGWGTPAQNT- 608
G+ + +G + S++T+ + + + S G T +T
Sbjct: 737 TE--------GSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTI 788
Query: 609 GTNLPSVEWNKLPSNQHSNDSANGNGKTFTNGWKSTEEEDQGSATSQTNEQSSVWAKTGG 668
G+ V ++ N +T ++E +A S+T S+ ++T
Sbjct: 789 GSETTKVS----TASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTT 844
Query: 669 TVESDGSTESTGRLE--EKGTGESQSRDRRKIDQHTLLQSIVNRTDLDPRVLSNSGWGQT 726
T ++GS +T E E T ++S + + + + S G T
Sbjct: 845 TTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETT 904
Query: 727 PIKQNTAWDTETSPRGERKTDNGTEAWGSSATQTFNSGACIDKTSPNGNDTSSVSGWG 784
+ T S G T TE GS T G+ + S G++T +VS G
Sbjct: 905 TASTEGSEITTVSTTGSETTTASTE--GSETTTASTEGSELTTVSTTGSETITVSAEG 960
Score = 39.3 bits (90), Expect = 0.038
Identities = 79/376 (21%), Positives = 132/376 (35%), Gaps = 30/376 (7%)
Query: 201 STSGSHYENSQRGPVSSTSDSSTNCKNAVVSDLSEKEAWPSAPGSDPELAS-ECMDADSA 259
ST GS + +T+ S+ + VS + S GS+ AS E + +
Sbjct: 887 STEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTV 946
Query: 260 SSSESERNITIMASGN------TGGEKDGLRNSTGLGSQNKFVVGSSSNNVGHGSSTGPW 313
S++ SE IT+ A G+ T G + ++ G + GS + S
Sbjct: 947 STTGSE-TITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTT 1005
Query: 314 GFSHGAIISTCQVSVDAPESKSESSNNRMNAWGTVSSSSNGGL--NPSTLNSASNHGAWP 371
S G+ T VS E+ S+ T + S + S + S G+
Sbjct: 1006 VSSTGS--ETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGS-- 1061
Query: 372 VLENNGLALKGPVGSGSSGINIQCSTIGQMPNNQSINSKVSGGSTHGTWGSLQETCESEV 431
E ++ G + +S +++ +T +++ SG +T T GS ET +
Sbjct: 1062 --ETTTVSTTGSETTTASTADLETTT---------VSTSGSGTTTASTAGS--ETTTVYI 1108
Query: 432 SGTQKVSFSGQPQNITTEMTGPNNTTNFMTSSLPNSGSVQNNELPSSNTGAWRVSTMNHP 491
+G++ + S + TT T + TT T+S S S T + +
Sbjct: 1109 TGSKTTTASTEGSEATTVSTTSSETT---TASTTGSEMTTVFTTVSETTTVSTIGSEATT 1165
Query: 492 QMQAPSGMNGTSLSHLSNGESKSGGSYGTTWGAYGSNYSGDKCSGPNGQANGDTVNATLM 551
A S TS + + GS TT GS + SG T + T
Sbjct: 1166 SSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETST 1225
Query: 552 QPGVNGPMGTNFQVNT 567
T F + +
Sbjct: 1226 PSSAGSETNTAFIIGS 1241
Score = 32.7 bits (73), Expect = 3.6
Identities = 52/276 (18%), Positives = 100/276 (36%), Gaps = 41/276 (14%)
Query: 175 SSALTNQQPQNNGEVQNSKNQSDINHSTSGSHYENSQRGPVSSTSDSSTNCKNAVVSDLS 234
S A T+ + +++ ST+GS + +T+ S++ +
Sbjct: 1161 SEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTG 1220
Query: 235 EKEAWPSAPGSDPELA----SECMDADSASSSESERNITIMASGNTGGEKDGLRNSTGLG 290
+ + PS+ GS+ A SE A +AS + ++T + G ++
Sbjct: 1221 SETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTV 1280
Query: 291 SQNKFVVGSSSNNVGHGSSTGPWGFSHGAIISTCQVSVDAPESKSESSNNRMNAWGTVSS 350
S FV+ +++ + Q + P S + ++ R+ A +V+
Sbjct: 1281 SSTTFVLTKATD-------------------VSIQPITNTPMSGTRTTGTRLTASSSVTM 1321
Query: 351 SSNGGLNPSTLNSASNHGAWPVLENNGLALKGPVGSGSSGINIQCSTIGQMPNNQSINSK 410
+ G++ T ++AS+ VL +GL ST+G + +
Sbjct: 1322 AP--GMD-FTASAASHTVPGIVLNTSGLG---------------TSTMGASSTTSAHGVR 1363
Query: 411 VSGGSTHGTWGSLQETCESEVSGTQKVSFSGQPQNI 446
+ GST S + GT VS S P N+
Sbjct: 1364 TTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTNV 1399
>gi|33286444 mastermind-like 2 [Homo sapiens]
Length = 1156
Score = 71.6 bits (174), Expect = 7e-12
Identities = 97/413 (23%), Positives = 164/413 (39%), Gaps = 53/413 (12%)
Query: 45 QKKATEQKIKVPEQIKPSVSQPQPANSNNGTSTATSTNNNAKRATANNQQPQQQQQQQQP 104
Q++ +Q+ + +Q + Q Q ++ S ++ ++ + Q QQQQQQQQ
Sbjct: 590 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQ 649
Query: 105 QQQQPQQQPQPQPQQQQPQQQPQALPRYPREVPPRFRHQEHKQLLKRGQHFPVIAANLGS 164
QQQQ QQQ Q Q QQQ Q Q+LP P P Q K LL++ Q+ P+ A +G
Sbjct: 650 QQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQ--KLLLQQMQNQPI--AGMGY 705
Query: 165 AVKVLNSQSESSALTNQQPQNNGEVQNSKNQSDINHSTSGSHYENSQRGPVSSTSDSSTN 224
V Q + S + QN G S + + ++ +GS Y NSQ+ S +
Sbjct: 706 QVSQQQRQDQHSVV----GQNTGP---SPSPNPCSNPNTGSGYMNSQQ---SLLNQQLMG 755
Query: 225 CKNAVVSDLSEKEAWPSAPGSDPELASECMDADSASSSESERNITIMASGNTGGEKDGLR 284
K + + E++ L + M AD+ + ++ I S KD R
Sbjct: 756 KKQTLQRQIMEQK--------QQLLLQQQMLADAEKIAPQDQ-INRHLSRPPPDYKDQRR 806
Query: 285 NSTGLGSQNKFVVGSSSNNVGHGS--------------STGPWGFSHGAIISTCQVSVDA 330
N + ++ GSS+ ++ ++ SHG + + +V
Sbjct: 807 NVGNMQPTAQYSGGSSTISLNSNQALANPVSTHTILTPNSSLLSTSHGTRMPSLSTAVQN 866
Query: 331 PESKSESSNNRMNAWGTVSSSS--NGGLNPSTLNSASNHGAWP------VLENNGLALKG 382
N+ N + S + NP L + N+ P NN +A
Sbjct: 867 MGMYGNLPCNQPNTYSVTSGMNQLTQQRNPKQLLANQNNPMMPRPPTLGPSNNNNVA--- 923
Query: 383 PVGSGSSGINIQ-----CSTIGQMPNNQSINSKVSGGSTHGTWGSLQETCESE 430
G+GS G + Q ++ MP ++ N ++ +T W S + T + +
Sbjct: 924 TFGAGSVGNSQQLRPNLTHSMASMPPQRTSNVMITSNTTAPNWASQEGTSKQQ 976
Score = 59.7 bits (143), Expect = 3e-08
Identities = 112/494 (22%), Positives = 170/494 (34%), Gaps = 106/494 (21%)
Query: 1341 AAQPRGMQQPPAQPLSSSQPNLRAQVPPPLLSPQVPVSLLKYAPNNGGLNPLFGPQQVAM 1400
A +PR P +S Q N Q P +L Q SLL Y QQ
Sbjct: 548 AMEPRQGNTKPLFHFNSDQAN---QQMPSVLPSQNKPSLLHYT------------QQQQQ 592
Query: 1401 LNQLSQLNQLSQISQLQRLLAQQQRAQSQRSVPSGNRPQQDQQGRPLSVQQQMMQQSRQL 1460
Q Q Q Q Q Q+ QQQ+ Q Q S+ + QQ QQ +S QQQ QQ +Q
Sbjct: 593 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISA---QQQQQQQSSISAQQQQQQQQQQQ 649
Query: 1461 DPNLLVKQQTPPSQQQPLHQPAM----KSFLDNVMP------------------------ 1492
+QQ QQQP QPA + L + +P
Sbjct: 650 QQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQ 709
Query: 1493 ------HTTPELQKGPSPINAFSNFPIGLNSNLNVNMDMNSIKEPQSRLRKWTTVDSISV 1546
H+ GPSP N N N + QS L + ++
Sbjct: 710 QQRQDQHSVVGQNTGPSP---------SPNPCSNPNTGSGYMNSQQSLLNQQLMGKKQTL 760
Query: 1547 NTSLDQNSSKHGAISSGFRLEESPFVPYDFMNSSTSPASPP-----GSIGDGWPRAKSPN 1601
+ + + + P D +N S P ++G+ P A+
Sbjct: 761 QRQI-MEQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPPDYKDQRRNVGNMQPTAQYSG 819
Query: 1602 GSSSVNWPPEFRPGEPWKGYPNIDPETDPYVTPGSVINNLSINTVREVDHLRDRNSGSSS 1661
GSS+++ P T +TP S + + S T +N G
Sbjct: 820 GSSTISLNSNQALANP--------VSTHTILTPNSSLLSTSHGTRMPSLSTAVQNMGMYG 871
Query: 1662 SLNTTLPSTSAWSS------------IRASNYNVPLSSTAQSTSARNSDSKLTWSPGSVT 1709
+L P+T + +S +N N P+ + N+++ T+ GSV
Sbjct: 872 NLPCNQPNTYSVTSGMNQLTQQRNPKQLLANQNNPMMPRPPTLGPSNNNNVATFGAGSVG 931
Query: 1710 NT-----SLAHELWKVP-------LPPKNITAPS-RPPPGLTGQKPPLSTWDNSPLRIGG 1756
N+ +L H + +P + N TAP+ G + Q+ L+ ++ +R
Sbjct: 932 NSQQLRPNLTHSMASMPPQRTSNVMITSNTTAPNWASQEGTSKQQEALT---SAGVRFPT 988
Query: 1757 GWGNSDARYTPGSS 1770
G + A YTP S
Sbjct: 989 G---TPAAYTPNQS 999
Score = 51.2 bits (121), Expect = 1e-05
Identities = 28/58 (48%), Positives = 33/58 (56%)
Query: 70 NSNNGTSTATSTNNNAKRATANNQQPQQQQQQQQPQQQQPQQQPQPQPQQQQPQQQPQ 127
NS+ S + + + + QQQQQQQQ QQQQ QQQ Q Q QQQQ QQQ Q
Sbjct: 563 NSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 620
Score = 40.0 bits (92), Expect = 0.022
Identities = 51/224 (22%), Positives = 85/224 (37%), Gaps = 32/224 (14%)
Query: 16 LSRDLVQEEEQLMEEKKKKKDDKKKKEAAQKKATEQKIKVPEQIKPSVSQPQPANSNNGT 75
L L +++ L+++ + + + +Q++ +Q V + PS S +N N G+
Sbjct: 680 LRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGS 739
Query: 76 STATSTNNNAKRATANNQQPQQQQQQQQPQQQQPQQQPQPQPQQQQPQQQPQALPRYPRE 135
S + + +Q Q+Q +Q QQ QQQ ++ PQ Q + R+
Sbjct: 740 GYMNSQQSLLNQQLMGKKQTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQ---INRHLSR 796
Query: 136 VPPRFRHQEHKQLLKRGQHFPVIAANLGSAVKVLNSQS--------------ESSALT-- 179
PP ++ Q G P + GS+ LNS SS L+
Sbjct: 797 PPPDYKDQRRNV----GNMQPTAQYSGGSSTISLNSNQALANPVSTHTILTPNSSLLSTS 852
Query: 180 --NQQPQNNGEVQNSK-------NQSDINHSTSGSHYENSQRGP 214
+ P + VQN NQ + TSG + QR P
Sbjct: 853 HGTRMPSLSTAVQNMGMYGNLPCNQPNTYSVTSGMNQLTQQRNP 896
Score = 37.0 bits (84), Expect = 0.19
Identities = 74/356 (20%), Positives = 126/356 (35%), Gaps = 50/356 (14%)
Query: 1286 ESQNMQFMSSQSMKLPPSNSALPNQALGSIAGLGMQNLNSVRQNGNPSMFGVGNTAAQPR 1345
+ Q Q Q + S SA Q S Q +Q Q +
Sbjct: 606 QQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQ----QQQQQQQ 661
Query: 1346 GMQQPPAQPLSS--SQPNLRAQVPPPLLSPQVPVSLLKYAPNNGGLNPLFGPQQVAMLNQ 1403
QQP +QP S SQP LR+ +P L ++ + ++ P G M Q
Sbjct: 662 QQQQPSSQPAQSLPSQPLLRSPLP---LQQKLLLQQMQNQPIAG------------MGYQ 706
Query: 1404 LSQLNQLSQISQLQRLLAQQQRAQSQRSVPSGNRPQQDQQ--------GRPLSVQQQMMQ 1455
+SQ + Q S + + + +G+ QQ G+ ++Q+Q+M+
Sbjct: 707 VSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKKQTLQRQIME 766
Query: 1456 QSRQLDPNLLVKQQTPPSQQQPLHQPAMKSFLDNVMP------------HTTPELQKGPS 1503
Q +Q LL++QQ ++ Q + L P T + G S
Sbjct: 767 QKQQ----LLLQQQMLADAEKIAPQDQINRHLSRPPPDYKDQRRNVGNMQPTAQYSGGSS 822
Query: 1504 PINAFSN----FPIGLNSNLNVNMDMNSIKEPQSRLRKWTTVDSISVNTSLDQNSSKHGA 1559
I+ SN P+ ++ L N + S T V ++ + +L N +
Sbjct: 823 TISLNSNQALANPVSTHTILTPNSSLLSTSHGTRMPSLSTAVQNMGMYGNLPCNQPNTYS 882
Query: 1560 ISSGFRLEESPFVPYDFMNSSTSPASP-PGSIGDGWPRAKSPNGSSSVNWPPEFRP 1614
++SG P + + +P P P ++G + G+ SV + RP
Sbjct: 883 VTSGMNQLTQQRNPKQLLANQNNPMMPRPPTLGPSNNNNVATFGAGSVGNSQQLRP 938
Score = 31.6 bits (70), Expect = 8.0
Identities = 28/85 (32%), Positives = 35/85 (41%), Gaps = 2/85 (2%)
Query: 1340 TAAQPRGMQQPPAQPLSSSQPNLRAQVPPPLLSPQVPVSLLKYAPNNGGLNPLFGPQQVA 1399
TAA PPA P ++SQ A PPP L + NNGG + G QQ
Sbjct: 98 TAATTTAPPPPPAAPPAASQAAATAAPPPPPDYHHHHQQHLLNSSNNGGSGGINGEQQPP 157
Query: 1400 MLNQLSQLNQLSQISQLQRLLAQQQ 1424
Q N S + LQ L ++Q
Sbjct: 158 ASTPGDQRN--SALIALQGSLKRKQ 180
>gi|62122917 filaggrin family member 2 [Homo sapiens]
Length = 2391
Score = 70.9 bits (172), Expect = 1e-11
Identities = 148/655 (22%), Positives = 219/655 (33%), Gaps = 130/655 (19%)
Query: 273 SGNTGGEKDGLRNSTGLGSQNKFVVGSSSNNVGHGSSTGPWGFSHGAIISTCQVSVDAPE 332
S G G S+G G SS G GSS HG+ S+ Q S
Sbjct: 665 SSGFGQHVSGSGQSSGFGQHESRSGHSSYGQHGFGSSQSSGYGQHGS--SSGQTSGFGQH 722
Query: 333 SKSESSNNRMNAWGTVSSSSNG-GLNPSTLNSASNHGAWPVLENNGLALKGPVGSGSSGI 391
S ++ G+ S S+G G + S +S G +G + G SGSS
Sbjct: 723 ELSSGQSSSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQHE--SRSGQSSYGQHSSGSS-- 778
Query: 392 NIQCSTIGQMPNNQSINSKVSGGSTHGTWGSLQETCESEVSGTQKVSFSGQPQNITTEMT 451
Q S GQ + Q+ SG HG+ GS Q T + S SGQ +
Sbjct: 779 --QSSGYGQHGSRQT-----SGFGQHGS-GSSQSTGFGQYG-----SGSGQSAGFGQHGS 825
Query: 452 GPNNTTNF-------MTSSLPNSGSVQNNELPSSNTGAWRVSTMNHPQMQAPSGMNGTSL 504
G ++ F SS GS + G+ T Q ++ SG
Sbjct: 826 GSGQSSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQYSGFG 885
Query: 505 SHLS-NGESKSGGSYGT------------------TWGAYGSNYSGDKCSGPNGQANGDT 545
H S +G+S G +GT ++G +GS S G +G ++G T
Sbjct: 886 QHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQT 945
Query: 546 VNATLMQPGVNGPMGTNFQVNTNKGGGVWESGAANSQSTSWGSGNGANSGGSRRGWGTPA 605
G G SG+ S SG G + GS + G
Sbjct: 946 F-----------------------GFGQHRSGSGQS------SGFGQHGSGSGQSSGFGQ 976
Query: 606 QNTGTNLPSVEWNKLPSNQHSNDSANGNGKTFTNGWKSTEEEDQGSATSQTNEQSSVWAK 665
+G+ S + SN +G+G + ++G+ G T +SS
Sbjct: 977 HESGSGKSSGFGQHESRSSQSNYGQHGSGSSQSSGY-GQHGSSSGQTTGFGQHRSSSGQY 1035
Query: 666 TGGTVESDGSTESTGRLEEKGTGESQSRDRRKIDQHTLLQSIVNRTDLDPRVLSNSGWGQ 725
+G GS +S+G + GTG QS SG+GQ
Sbjct: 1036 SGFGQHGSGSDQSSG-FGQHGTGSGQS----------------------------SGFGQ 1066
Query: 726 TPIKQNTAWDTETSPRGERKTDNGTEAWGSSATQTFNSGACIDKTSPNGNDTSSVSGWGD 785
+ R++ G GSS + + +G+++ SG+G
Sbjct: 1067 YESR-------------SRQSSYGQHGSGSSQSSGYGQ---------HGSNSGQTSGFGQ 1104
Query: 786 PKPALRWGDSKGSNCQGGWEDDSAATGMVKSNQWGNCKEEKAAWNDSQKNKQGWGDGQKS 845
+P G S G G S+ G S + + + Q + G G
Sbjct: 1105 HRPGS--GQSSGFGQYGSGSGQSSGFGQHGSGTGKSSGFAQHEYRSGQSSYGQHGTGSSQ 1162
Query: 846 SQGWSVSASDNWGETSRNNHWGEANKKSSSGGSDSDRSVS-GWNELGKTSSFTWG 899
S G S + TS H ++ SSSG SD S G+ + G S + G
Sbjct: 1163 SSGCGQHESGSGPTTSFGQHVSGSDNFSSSGQHISDSGQSTGFGQYGSGSGQSTG 1217
Score = 56.6 bits (135), Expect = 2e-07
Identities = 100/455 (21%), Positives = 160/455 (35%), Gaps = 51/455 (11%)
Query: 507 LSNGESKSGGSYGTTWGAYGSNYSGDKCSGPNGQANGDTVNATLMQPGVNGPMGTNFQVN 566
LS G SG +T G CSG G P +
Sbjct: 240 LSCGLETSGHESNSTQSRIREQKLGSSCSGSGDSGRRSHACGYSNSSGCGRPQNASSSCQ 299
Query: 567 TNKGGGVW------ESGAANSQSTSWGSGNGANSGGSRRGWGTPAQNTGTNLPSVEWNKL 620
+++ GG +SG + G G+G SGG G G P N + S +
Sbjct: 300 SHRFGGQGNQFSYIQSGCQSG--IKGGQGHGCVSGGQPSGCGQPESNPCSQSYS---QRG 354
Query: 621 PSNQHSNDSANGNGKTFTNGWKSTEEEDQGSATSQTNEQSSVWAKTGGTVESDGSTESTG 680
+ + N G+ T +S+ GS SQ+ + G + S+
Sbjct: 355 YGARENGQPQNCGGQWRTGSSQSSCCGQYGSGGSQSCSNGQHEYGSCGRFSNSSSSNEFS 414
Query: 681 RLEEKGTGESQSRDRRKIDQHTLLQSIVNRTDLDPRVLSNS---GWGQTPIKQNTAWDTE 737
+ ++ G+G SQS +QH + + + V + G ++ Q+ +D
Sbjct: 415 KCDQYGSGSSQS---TSFEQHG--TGLSQSSGFEQHVCGSGQTCGQHESTSSQSLGYDQH 469
Query: 738 TSPRGERKTDNGTEAWGSSATQTFNSGACIDKTSPNGNDTSSVSGWGDPKPALRWGDSKG 797
S G+ +G GS + Q+ G C G+ + SG+G G S G
Sbjct: 470 GSSSGK---TSGFGQHGSGSGQSSGFGQC-------GSGSGQSSGFGQHGSVS--GQSSG 517
Query: 798 SNCQGGWEDDSAATGMVKS-------NQWGNCKEEKAAWND------SQKNKQGWGDGQK 844
G S+ G +S Q G+ + + + S + G G GQ
Sbjct: 518 FGQHGSVSGQSSGFGQHESRSRQSSYGQHGSGSSQSSGYGQYGSRETSGFGQHGLGSGQS 577
Query: 845 SSQGWSVSASDNWGETSRNNHWGEANKKSSSGG---SDSDRSVSGWNELGKTSSFTWGNN 901
+ G S S G++S G + +SS G S S +S G + G + S +G +
Sbjct: 578 TGFGQYGSGS---GQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQH 634
Query: 902 INPNNSSGWDESSKPTPSQGWGD-PPKSNQSLGWG 935
+ S S + S G+G S QS G+G
Sbjct: 635 GSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSSGFG 669
Score = 45.4 bits (106), Expect = 5e-04
Identities = 212/1111 (19%), Positives = 366/1111 (32%), Gaps = 187/1111 (16%)
Query: 70 NSNNGTSTATSTNNNAKRATANNQQPQQQQQQQQPQQQQPQQQPQPQPQQQQPQQQPQAL 129
+S +G ST + +R + +++ + + Q Q+Q Q Q +
Sbjct: 1403 HSGHGQSTQRGSRTTGRRGSGHSESSDSEVHSGGSHRPQSQEQTHGQAGSQHGESGSTVH 1462
Query: 130 PRYPREV-----PPRFRHQEHKQLLKRG-----QHFPVIAANLGSAVKVLNSQSESSALT 179
R+ R H H + +RG + + + S V S + S
Sbjct: 1463 GRHGTTHGQTGDTTRHAHYHHGKSTQRGSSTTGRRGSGHSESSDSEVHSGGSHTHSGHTH 1522
Query: 180 NQQPQNNGEVQNS-KNQSDINHSTSGSHYENSQRGPVSSTSDSSTNCKNAVVSDLSEKEA 238
Q +GE ++ ++ I H +G +S G +T S S ++
Sbjct: 1523 GQSGSQHGESESIIHDRHRITHGQTGDTTRHSYSGHEQTTQTGSRTTGRQRTSHSESTDS 1582
Query: 239 WPSAPGSDPELASECMDADSASSSESERNITIMASGNTGGE-------------KDGLRN 285
+ GS + E + S E G T G+ + R
Sbjct: 1583 EVHSGGSHRPHSREHTYGQAGSQHEEPEFTVHERHGTTHGQIGDTTGHSHSGHGQSTQRG 1642
Query: 286 STGLGSQNKFVVGSSSNNVGHGSSTGPWGFSHGAIISTCQVSVDAPESKSESSNNRMNAW 345
S G Q SS + V G S G +HG A +S +
Sbjct: 1643 SRTTGRQRSSHSESSDSEVHSGVSHTHTGHTHG----------QAGSQHGQSESIVPERH 1692
Query: 346 GTVSSSSNGGLNPSTLNSASNHGAWPVLENNGLALKGPVGSGSSGINIQCSTIGQMPNNQ 405
GT ++G +T ++ +HG + G G GSG S + G
Sbjct: 1693 GT----THGQTGDTTRHAHYHHG---LTTQTGSRTTGRRGSGHSEYSDSEGYSGV----- 1740
Query: 406 SINSKVSGGSTHGTWGSLQETCESEVSGTQKVSFSGQPQNITTEMTGPNNTTNFMTSSLP 465
S G THG Q S G+ ++I E G + T+
Sbjct: 1741 ---SHTHSGHTHG----------------QARSQHGESESIVHERHGTIHGQTGDTTRHA 1781
Query: 466 NSGSVQNNELPSSNTGAWRVSTMNHPQMQAPSGMN----------GTSLSHLSNGESKSG 515
+SG Q+ + S TG + + SG + G + S ES
Sbjct: 1782 HSGHGQSTQTGSRTTGRRSSGHSEYSDSEGHSGFSQRPHSRGHTHGQAGSQHGESESIVD 1841
Query: 516 GSYGTTWGAYGSNYSGDKCSGPNGQANGDTVNATLMQPGVNGPMGTNFQVNTNKGGGVWE 575
+GTT G G SG SG +GQ+ + T + + + + GG
Sbjct: 1842 ERHGTTHGQTGDT-SGHSQSG-HGQSTQSGSSTTGRRRSGHSESSDS---EVHSGGSHTH 1896
Query: 576 SGAANSQSTSWGSGNGANSGGSRRGWGTPAQNTGTNLPSVEWNKLPSNQHSNDSANGNGK 635
SG +SQ+ S +G + + T TG + +H + S +G+
Sbjct: 1897 SGHTHSQARSQ---HGESESTVHKRHQTTHGQTGD-----------TTEHGHPS---HGQ 1939
Query: 636 TFTNGWKSTEEEDQGSATSQTNEQSSVWAKT--GGTVESDGS--TESTGRLEEK-GTGES 690
T G ++T G + +E S + T G T GS ES + E+ GT
Sbjct: 1940 TIQTGSRTTGRRGSGHSEYSDSEGPSGVSHTHSGHTHGQAGSHYPESGSSVHERHGTTHG 1999
Query: 691 QSRDRRKIDQHTLLQSIVNRTDLDPRVLSNSGWGQTPIKQNTAWDTETSPRGERKTDNGT 750
Q+ D + QS T R G ++ + G T +G
Sbjct: 2000 QTADTTRHGHSGHGQS----TQRGSRTTGRRASG------HSEYSDSEGHSGVSHTHSG- 2048
Query: 751 EAWGSSATQTFNSGACIDK----TSPNGNDTSSVSGWGDPKPALRWGDSKGSNCQGGWE- 805
A G + +Q SG+ + + T DT+ + G + R + G G E
Sbjct: 2049 HAHGQAGSQHGESGSSVHERHGTTHGQTGDTTRHAHSGHGQSTQRGSRTAGRRGSGHSES 2108
Query: 806 -DDSAATGMVKSNQ---WGNCKEEKAAWNDSQKNKQGWGDGQKSSQGWSVSASDNWGETS 861
D +G+ ++ +G + + + +QG GQ G+T+
Sbjct: 2109 SDSEVHSGVSHTHSGHTYGQARSQHGESGSAIHGRQGTIHGQT-------------GDTT 2155
Query: 862 RNNHWGEANKKSS----SGGSDSDRSVSGWNELGKTSSFTWGNNINP-----NNSSGWDE 912
R+ G + +G S S S +E+ +S T + + + SG
Sbjct: 2156 RHGQSGHGQSTQTGSRTTGRQRSSHSESSDSEVHSEASPTHSGHTHSQAGSRHGQSGSSG 2215
Query: 913 SSKPTPSQGWGDPPKSNQSLGWGDSSKPVS-------SPDWNKQQDIVGSWGIPPATGKP 965
+ + G + G+G S++ S S V SWG +G
Sbjct: 2216 HGRQGTTHGQTGDTTRHAHYGYGQSTQRGSRTTGRRGSGHSESSDSEVHSWGSHTHSGHI 2275
Query: 966 PGTGWLGGPIPAPAKEEEPTGWEEPSPESIRRKMEIDDGTSAWGDPSKYNYKNVNMWNKN 1025
G A +++ +P ++ ++E G + GD +++ + + ++
Sbjct: 2276 QGQ--------AGSQQRQPGS-------TVHGRLETTHGQT--GDTTRHGHSG---YGQS 2315
Query: 1026 VPNGNSRSDQQAQVHQLLTPASAISNKEASSGSGWGEPWGEPSTPATTVDNGTSAWGKPI 1085
G SRS + + S+ G + W S D G + +G
Sbjct: 2316 TQTG-SRSSRASHFQ---------SHSSERQRHGSSQVWKHGSYGPAEYDYGHTGYG--- 2362
Query: 1086 DSGPSWGEPIAAASSTSTWGSSSVGPQALSK 1116
PS G + ++S +W + S + LS+
Sbjct: 2363 ---PSGGSRKSISNSHLSWSTDSTANKQLSR 2390
Score = 43.5 bits (101), Expect = 0.002
Identities = 124/681 (18%), Positives = 233/681 (34%), Gaps = 86/681 (12%)
Query: 62 SVSQPQPANSNNGTSTATSTNNNAKRATANNQQPQQQQQQQQPQQQQPQQQPQP---QPQ 118
+++ + + S G ST T + +R ++ ++ + + + Q P+
Sbjct: 1243 TINTTRHSQSGQGQSTQTGSRVTRRRRSSQSENSDSEVHSKVSHRHSEHIHTQAGSHYPK 1302
Query: 119 QQQPQQQPQALPRYPREVPPRFRHQEHKQLLKRGQHFPVIAANLGSAVKVLNSQSESSAL 178
++ Q R R H H Q + G S
Sbjct: 1303 SGSTVRRRQGTTHGQRGDTTRHGHSGHGQSTQTG-----------------------SRT 1339
Query: 179 TNQQPQNNGEVQNSKNQSDINHSTSGSHYENSQRGPVSSTSDSSTNCKNAVVSDLSEKEA 238
+ +Q ++ + +S+ S ++H +SQ G S+S+ + ++ + +
Sbjct: 1340 SGRQRFSHSDATDSEVHSGVSHRPHSQEQTHSQAGSQHGESESTVHERHETTYGQTGEAT 1399
Query: 239 WPSAPGSDPELASECMDADSASSSESERNITIMASGNTGGEKDGLRNSTGLGSQNKFVVG 298
G S SE + + + SG + + + GSQ+ G
Sbjct: 1400 GHGHSGHGQSTQRGSRTTGRRGSGHSESSDSEVHSGGSHRPQSQEQTHGQAGSQH----G 1455
Query: 299 SSSNNVG--HGSSTGPWG-------FSHGAIISTCQVSVDAPES-KSESSNNRMNAWGTV 348
S + V HG++ G G + HG + S SESS++ +++ G+
Sbjct: 1456 ESGSTVHGRHGTTHGQTGDTTRHAHYHHGKSTQRGSSTTGRRGSGHSESSDSEVHSGGSH 1515
Query: 349 SSSSNGGLNPSTLNSASNHG-AWPVLENNGLALKGPVGSGS----SGINIQCSTIGQMPN 403
+ S + + S S HG + ++ + G G + SG T +
Sbjct: 1516 THSGH-----THGQSGSQHGESESIIHDRHRITHGQTGDTTRHSYSGHEQTTQTGSRTTG 1570
Query: 404 NQSINSKVSGGSTHGTWGSLQETCESEVSGTQKVSFSGQPQNITTEMTGPNNTTNFMTSS 463
Q + S S + GS + G Q S +P+ E G + T+
Sbjct: 1571 RQRTSHSESTDSEVHSGGSHRPHSREHTYG-QAGSQHEEPEFTVHERHGTTHGQIGDTTG 1629
Query: 464 LPNSGSVQNNELPSSNTGAWRVSTMNHPQMQAPSGMNGTSLSHL------SNGESKS--G 515
+SG Q+ + S TG R S + SG++ T H +G+S+S
Sbjct: 1630 HSHSGHGQSTQRGSRTTGRQRSSHSESSDSEVHSGVSHTHTGHTHGQAGSQHGQSESIVP 1689
Query: 516 GSYGTTWGAYG------------SNYSGDKCSGPNGQANGDTVNATLMQPGVNGPMGTNF 563
+GTT G G + +G + +G G + + ++ GV+ +
Sbjct: 1690 ERHGTTHGQTGDTTRHAHYHHGLTTQTGSRTTGRRGSGHSEYSDSE-GYSGVSHTHSGHT 1748
Query: 564 QVNTNKGGGVWESGAANSQSTSWG----------SGNGANSGGSRRGWGTPAQNTGTNLP 613
G ES T G SG+G ++ R G +
Sbjct: 1749 HGQARSQHGESESIVHERHGTIHGQTGDTTRHAHSGHGQSTQTGSRTTGRRSSGHSEYSD 1808
Query: 614 SVEWNKLPSNQHSNDSANGNGKTFTNGWKSTEEEDQGSATSQTNEQSSVWAKTGGTVESD 673
S + HS +G + +S +E G+ QT + S +++G +
Sbjct: 1809 SEGHSGFSQRPHSRGHTHGQAGSQHGESESIVDERHGTTHGQTGDTSG-HSQSGHGQSTQ 1867
Query: 674 GSTESTGRLEEKGTGESQSRD 694
+ +TGR + +G S+S D
Sbjct: 1868 SGSSTTGR---RRSGHSESSD 1885
>gi|33356174 pinin, desmosome associated protein [Homo sapiens]
Length = 717
Score = 68.9 bits (167), Expect = 5e-11
Identities = 71/340 (20%), Positives = 134/340 (39%), Gaps = 60/340 (17%)
Query: 11 DVERNLSRDLVQEEEQLMEEKKKKKDDKKKKEAAQKKATEQKIKVPEQIKPSVSQPQPAN 70
D E+ + ++E ++ E++ + + +K++ +Q + +++ E +K ++ +
Sbjct: 348 DAEKEQEEEEQKQEMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVME 407
Query: 71 SNNGTSTATSTNNNAKR------------------------ATANNQQPQQQQQQQQPQQ 106
+N S S N +K +A + + + ++++++ +
Sbjct: 408 TNRVESVEPSENEASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESE 467
Query: 107 QQPQQQPQPQPQ---------------QQQPQQQPQALPRYPREVPPRFRHQEHKQLLKR 151
QP+ QPQPQ Q QP QP+ L + P+ QE LL
Sbjct: 468 PQPEPVAQPQPQSQPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVT-QEQGHLLPE 526
Query: 152 GQHFPVIAANLGS--AVKVLNSQSESSALTNQQPQNNGEVQNSKNQSDINHSTSGSHYEN 209
+ FPV + L VL ES + T + ++ G +N ++S S+S
Sbjct: 527 RKDFPVESVKLTEVPVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSS------ 580
Query: 210 SQRGPVSSTSDSSTNCKNAVVSDLSEKEAWPSAPGSDPELASECMDADSASSSESERNIT 269
SS+S SST+ + S + S+ S S D+ S++SS SE
Sbjct: 581 ------SSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSR 634
Query: 270 IMASGNTGGEKD------GLRNSTGLGSQNKFVVGSSSNN 303
G+ K R+++GL +K G SS +
Sbjct: 635 SRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRD 674
Score = 34.7 bits (78), Expect = 0.94
Identities = 26/122 (21%), Positives = 54/122 (44%), Gaps = 1/122 (0%)
Query: 576 SGAANSQSTSWGSGNGANSGGSRRGWGTPAQNTGTNLPSVEWNKLPSNQHSNDSANGNGK 635
S +++S STS SG+ ++SG S + + ++ T+ S + ++ S + G+
Sbjct: 580 SSSSSSSSTSSSSGSSSSSGSS-SSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGR 638
Query: 636 TFTNGWKSTEEEDQGSATSQTNEQSSVWAKTGGTVESDGSTESTGRLEEKGTGESQSRDR 695
K D+ + E+S +K G + ++ GS + R + K + SR
Sbjct: 639 GHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISESSRSG 698
Query: 696 RK 697
++
Sbjct: 699 KR 700
>gi|33946327 nucleoporin 214kDa [Homo sapiens]
Length = 2090
Score = 68.2 bits (165), Expect = 8e-11
Identities = 153/674 (22%), Positives = 233/674 (34%), Gaps = 115/674 (17%)
Query: 187 GEVQNSKNQSDINHSTSGSHYENSQRGPVSSTSDSSTNCKNAVVSDLSEKEAWPSAPGS- 245
G + +S + S S E + DS + A + + + P AP
Sbjct: 1474 GSLLSSATTPSLPMSAGRSTEEATSSALPEKPGDSEVSASAASLLEEQQSAQLPQAPPQT 1533
Query: 246 ------DPELASECM-DADSASSSESERNITIMASGNTGGEKDGLRNSTGLGSQNKFVVG 298
+P LA + ++ +A+SS S ++ A+ T G D + S V G
Sbjct: 1534 SDSVKKEPVLAQPAVSNSGTAASSTSLVALSAEATPATTGVPDARTEAVPPASSFS-VPG 1592
Query: 299 SSSNNVGHGSSTGPWGFSHGAI-ISTCQVSVDAPESKSESSNNRMNAWGTVSSSSNGGLN 357
++ SS GP + I++ S+ AP +E++ A+GTV+S S+
Sbjct: 1593 QTAVTAAAISSAGPVAVETSSTPIASSTTSIVAPGPSAEAA-----AFGTVTSGSSVFAQ 1647
Query: 358 PSTLNSASNHGAWPVLENNGLALKGPVGSGSSGINIQCSTIGQMPNNQSINSKVSGGSTH 417
P P S SS N + P+ + +V+ +
Sbjct: 1648 P------------------------PAASSSSAFNQLTNNTATAPSATPVFGQVAASTAP 1683
Query: 418 GTWGSLQETCESEVSGTQKVSFSG--QPQNITTEMTGPNNTTNFMTSSLPNSGSVQNNEL 475
+G + S + T +VS SG P TT TT S S S +
Sbjct: 1684 SLFGQQTGSTASTAAATPQVSSSGFSSPAFGTTAPGVFGQTTFGQASVFGQSASSAASVF 1743
Query: 476 PSSNTGAWRVSTMNHPQMQAPSGMNGTSLSHLSNGESKSGGSYG-----TTWGAYGSN-- 528
S G V P P+ +G+ S+ S S S+G T G +G +
Sbjct: 1744 SFSQPGFSSVPAFGQPASSTPTSTSGSVFGAASSTSSSSSFSFGQSSPNTGGGLFGQSNA 1803
Query: 529 --YSGDKCSGPNGQANGDTVNAT---------LMQPGVNGPMGTN--FQVNTNKGGGVWE 575
+ G G G T AT Q G T F + GG V+
Sbjct: 1804 PAFGQSPGFGQGGSVFGGTSAATTTAATSGFSFCQASGFGSSNTGSVFGQAASTGGIVFG 1863
Query: 576 SGAANSQSTSWGSGNGANSGGSRRG-WGTPAQNTGTNLP----SVEWNKLPSNQHSNDSA 630
+++S + +GSGN GG G G P+Q+ P S + ++ SN
Sbjct: 1864 QQSSSSSGSVFGSGNTGRGGGFFSGLGGKPSQDAANKNPFSSASGGFGSTATSNTSNLFG 1923
Query: 631 NGNGKTFTNGWKSTEEEDQGSATSQTNEQSSVWAKTGGTVESDGSTESTGRLEEKGTGES 690
N KTF G A+S EQ K GT S G G + +G G S
Sbjct: 1924 NSGAKTF-----------GGFASSSFGEQ-----KPTGTFSSGG-----GSVASQGFGFS 1962
Query: 691 QSRDRRKIDQHTLLQSIVNRTDLDPRVLSNSGWGQTP-IKQNTAWDTETSPRGERKTDNG 749
+ S P + G+G P A+ + G + G
Sbjct: 1963 SPNKTGGFGAAPVFGS-------PPTFGGSPGFGGVPAFGSAPAFTSPLGSTGGKVFGEG 2015
Query: 750 TEA-------WGSSA-TQTFNS---------GACIDKTSPNGNDTSSVSGWGDPKPALRW 792
T A +GSS+ T +F + G+ +TS G +S SG+G +
Sbjct: 2016 TAAASAGGFGFGSSSNTTSFGTLASQNAPTFGSLSQQTSGFGTQSSGFSGFGSGTGGFSF 2075
Query: 793 GDSKGSNCQ--GGW 804
G S S+ Q GGW
Sbjct: 2076 G-SNNSSVQGFGGW 2088
>gi|161016767 mucin 21 [Homo sapiens]
Length = 566
Score = 66.2 bits (160), Expect = 3e-10
Identities = 112/507 (22%), Positives = 193/507 (38%), Gaps = 83/507 (16%)
Query: 319 AIISTCQVSVDAPESKSESSNNRMNAWGTVSSSSNGGLNPSTLNSASNHGAWPVLENNGL 378
A ++ + S A S S+ A + SS ++ G++ +T++ +S + +NG+
Sbjct: 20 AATNSNETSTSANTGSSVISSGASTATNSGSSVTSSGVSTATISGSS-------VTSNGV 72
Query: 379 AL--KGPVGSGSSGI----NIQCSTIGQ---MPNNQSINSKVSGGSTHGTWGSLQETCES 429
++ + SSGI N + ST+ + N ++ SG ST S
Sbjct: 73 SIVTNSEFHTTSSGISTATNSEFSTVSSGISIATNSESSTTSSGAST---------ATNS 123
Query: 430 EVSGTQKVSFSGQPQNITTEMTGPNNTTNFMTSSLPNSGSVQNNELPSSNTGAWRVSTMN 489
E S + + + +T +G + TN +S+ + S N S+T + ST
Sbjct: 124 ESSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEASTATNS--ESSTTSSGASTAT 181
Query: 490 HPQMQAPSGMNGTSLSHLSNGESKSGGSYGTTWGAYGSNYSGDKCSGPNGQANGDTVNAT 549
+ + S T+ +N ES + S G++ + + S G N+
Sbjct: 182 NSESSTVSSRASTA----TNSESSTTSS--------GASTATNSESRTTSNGAGTATNSE 229
Query: 550 LMQPGVNGPMGTNFQVNTNKGGGVWESGAANSQS--TSWGSGNGANSGGSRRGWG-TPAQ 606
TN + +T G A NS+S TS G+G NS S G +
Sbjct: 230 SSTTSSGASTATNSESSTPSSGA---GTATNSESSTTSSGAGTATNSESSTVSSGISTVT 286
Query: 607 NTGTNLPSVEWNKLPSNQHSNDSANGNGKTFTNGWKSTEEEDQGSATSQTNEQSSVWAKT 666
N+ ++ PS N +++ S S+ N T TN ST G++T+ +E S+ +
Sbjct: 287 NSESSTPSSGANTATNSESSTTSSGAN--TATNSDSST--TSSGASTATNSESSTTSSGA 342
Query: 667 GGTVESDGSTESTGRLEEKGTGESQSRDRRKIDQHTLLQSIVNRTDLDPRVLSNSGWGQT 726
S+ ST S+G +G S T +NS
Sbjct: 343 STATNSESSTTSSGASTATNSGSS-------------------TTSSGTSTATNSESSTV 383
Query: 727 PIKQNTAWDTETSPRGERKTDNGTEAWGSSATQTFNSGACIDKTSPNGNDTSSVSGWGDP 786
+TA +E+S T +G +S + T +SGA T+ N +++ SG
Sbjct: 384 SSGASTATTSESS-----TTSSGASTATNSESSTVSSGA---STATNSESSTTSSG---- 431
Query: 787 KPALRWGDSKGSNCQGGWEDDSAATGM 813
+ GS+ +A TGM
Sbjct: 432 ---ANTATNSGSSVTSAGSGTAALTGM 455
Score = 61.2 bits (147), Expect = 9e-09
Identities = 105/433 (24%), Positives = 160/433 (36%), Gaps = 59/433 (13%)
Query: 361 LNSASNHGAWPVLENNGLALKGPVGSGSSGINIQCSTIGQMPNNQSINSKVSGGSTHGTW 420
L +A+N N G ++ S ++ ++ G S +S S G + T
Sbjct: 18 LEAATNSNETSTSANTGSSVISSGASTATNSGSSVTSSGVSTATISGSSVTSNGVSIVT- 76
Query: 421 GSLQETCESEVSGTQKVSFSGQPQNITTEMTGPNNTTNFMTSSLPNSGSVQNNELPSSNT 480
S T S +S FS I+ ++TT+ S+ NS S PSS
Sbjct: 77 NSEFHTTSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSES----STPSSG- 131
Query: 481 GAWRVSTMNHPQMQAPSGMNGTSLSHLSNGESKSGGSYGTTWGAYGSNYSGDKCSGPNGQ 540
A + N S S S+G S + S +T + S + + S +
Sbjct: 132 --------------ASTATNSDS-STTSSGASTATNSDSSTTSSEASTATNSESSTTSSG 176
Query: 541 ANGDTVNATLMQPGVNGPMGTNFQVNTNKGGGVWESGAANSQS--TSWGSGNGANSGGSR 598
A+ T N+ TN + +T G S A NS+S TS G+G NS S
Sbjct: 177 ASTAT-NSESSTVSSRASTATNSESSTTSSGA---STATNSESRTTSNGAGTATNSESST 232
Query: 599 RGWGTPAQNTGTNLPSVEWNKLPSNQHSNDSANGNGKTFTNGWKSTEEEDQGSATSQTNE 658
G +T T N S+ ++G G T TN ST G+AT+ +E
Sbjct: 233 TSSGA---STAT------------NSESSTPSSGAG-TATNSESSTTSSGAGTATN--SE 274
Query: 659 QSSVWAKTGGTVESDGSTESTGRLEEKGTGESQSRDRRKIDQHTLLQSIVNRTDLDPRVL 718
S+V + S+ ST S+G T + +T S + T
Sbjct: 275 SSTVSSGISTVTNSESSTPSSG----ANTATNSESSTTSSGANTATNSDSSTTSSGASTA 330
Query: 719 SNSGWGQTPIKQNTAWDTETSP----------RGERKTDNGTEAWGSSATQTFNSGACID 768
+NS T +TA ++E+S G T +GT +S + T +SGA
Sbjct: 331 TNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGASTA 390
Query: 769 KTSPNGNDTSSVS 781
TS + +S S
Sbjct: 391 TTSESSTTSSGAS 403
Score = 59.7 bits (143), Expect = 3e-08
Identities = 90/405 (22%), Positives = 158/405 (39%), Gaps = 31/405 (7%)
Query: 159 AANLGSAVKVLNSQSESSALTNQQPQNNGE--VQNSK---NQSDINHSTSGSHYENSQRG 213
A N GS+V +S ++ ++ +NG V NS+ S I+ +T+ S
Sbjct: 45 ATNSGSSVT--SSGVSTATISGSSVTSNGVSIVTNSEFHTTSSGISTATNSEFSTVSSGI 102
Query: 214 PVSSTSDSSTNCKNAVVSDLSEKEAWPSAPGSDPELASECMDADSASSSESERNITIMAS 273
+++ S+SST A + SE S P S AS ++DS+++S T S
Sbjct: 103 SIATNSESSTTSSGASTATNSES----STPSSG---ASTATNSDSSTTSSGASTATNSDS 155
Query: 274 GNTGGEKDGLRNS----------TGLGSQNKFVVGSSSNNVGHGSSTGPWGFSHGAIIST 323
T E NS T S++ V +S SST G S A S
Sbjct: 156 STTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGAST-ATNSE 214
Query: 324 CQVSVDAPESKSESSNNRMNAWGTVSSSSNGGLNPSTLNSASNHGAWPVLENNGLALKGP 383
+ + + + + S ++ ++ + +++S S +A+N + G A
Sbjct: 215 SRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNSE 274
Query: 384 VGSGSSGINIQCSTIGQMPNNQSINSKVSGGSTHGTWGSLQETCESEVSGTQKVSFSGQP 443
+ SSGI+ ++ P++ + + S ST T S+ S T + +
Sbjct: 275 SSTVSSGISTVTNSESSTPSSGANTATNSESST--TSSGANTATNSDSSTTSSGASTATN 332
Query: 444 QNITTEMTGPNNTTNFMTSSLPNSGSVQNNELPSSNTGAWRVSTMNHPQMQAPSGMNGTS 503
+T +G + TN +S+ + S N SS T + + N SG + +
Sbjct: 333 SESSTTSSGASTATNSESSTTSSGASTATNS-GSSTTSSGTSTATNSESSTVSSGASTAT 391
Query: 504 LSH---LSNGESKSGGSYGTTWGAYGSNYSGDKCSGPNGQANGDT 545
S S+G S + S +T + S + + S + AN T
Sbjct: 392 TSESSTTSSGASTATNSESSTVSSGASTATNSESSTTSSGANTAT 436
Score = 56.6 bits (135), Expect = 2e-07
Identities = 98/447 (21%), Positives = 165/447 (36%), Gaps = 46/447 (10%)
Query: 493 MQAPSGMNGTSLSHLSNGES--KSGGSYGTTWGAY--GSNYSGDKCSGPNGQANGDTV-- 546
++A + N TS S + G S SG S T G+ S S SG + +NG ++
Sbjct: 18 LEAATNSNETSTS-ANTGSSVISSGASTATNSGSSVTSSGVSTATISGSSVTSNGVSIVT 76
Query: 547 NATLMQPGVNGPMGTNFQVNTNKGGGVWESGAANSQS--TSWGSGNGANSGGSRRGWGTP 604
N+ TN + +T G S A NS+S TS G+ NS S G
Sbjct: 77 NSEFHTTSSGISTATNSEFSTVSSG---ISIATNSESSTTSSGASTATNSESSTPSSGA- 132
Query: 605 AQNTGTNLPSVEWNKLPSNQHSNDSANGNGKTFTNGWKSTEEEDQGSATSQTNEQSSVWA 664
+T TN S + S ++DS+ + + T + G++T+ +E S+V +
Sbjct: 133 --STATNSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSS 190
Query: 665 KTGGTVESDGSTESTGRLEEKGTGESQSRDRRKIDQHTLLQSIVNRTDLDPRVLSNSGWG 724
+ S+ ST S+G T S T +NS
Sbjct: 191 RASTATNSESSTTSSG-------------------ASTATNSESRTTSNGAGTATNSESS 231
Query: 725 QTPIKQNTAWDTETSPRGERKTDNGTEAWGSSATQTFNSGACIDKTSPNGNDTSSVSGWG 784
T +TA ++E+S +G +S + T +SGA T+ N ++ SG
Sbjct: 232 TTSSGASTATNSESS-----TPSSGAGTATNSESSTTSSGA---GTATNSESSTVSSGIS 283
Query: 785 DPKPALRWGDSKGSNCQGGWEDDSAATGMVKSNQWGNCKEEKAAWNDSQKNKQGWGDGQK 844
+ S G+N E + ++G + + A + G
Sbjct: 284 TVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGAS 343
Query: 845 SSQGWSVSASDNWGETSRNNHWGEANKKSSSGGSDSDRSVSGWNELGKTSSFTWGNNINP 904
++ S + + T+ N+ + +SSG S + S S G +++ T ++
Sbjct: 344 TATNSESSTTSSGASTATNS----GSSTTSSGTSTATNSESSTVSSGASTATTSESSTTS 399
Query: 905 NNSSGWDESSKPTPSQGWGDPPKSNQS 931
+ +S S T S G S S
Sbjct: 400 SGASTATNSESSTVSSGASTATNSESS 426
Score = 55.1 bits (131), Expect = 7e-07
Identities = 77/383 (20%), Positives = 145/383 (37%), Gaps = 23/383 (6%)
Query: 155 FPVIAANLGSAVKVLNSQSESSA--LTNQQPQNNGEVQNSKNQSDINHSTSG-SHYENSQ 211
F +++ + A +S + S A TN + ++ SD + ++SG S NS
Sbjct: 95 FSTVSSGISIATNSESSTTSSGASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSD 154
Query: 212 RGPVSS------TSDSSTNCKNAVVSDLSEKEAWPSAPGSDPELASECMDADSASSSESE 265
SS S+SST A + SE S + S + +++++ SE
Sbjct: 155 SSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNSE 214
Query: 266 RNITIMASGNTGGEKDGLRNSTGLGSQNKFVVGSSSNNVGHGSSTGPWGFSHGAIISTCQ 325
T +G T + S+G + + S+ G +++ S GA +T
Sbjct: 215 SRTTSNGAG-TATNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNS 273
Query: 326 VSVDAPESKSESSNNRM---NAWGTVSSSSNGGLNPSTLNSASNHGAWPVLENNGLALKG 382
S S +N+ ++ +++S S N+A+N + A
Sbjct: 274 ESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGASTATNS 333
Query: 383 PVGSGSSGINIQCSTIGQMPNNQSINSKVSGGSTHGTWGSLQETCESEVSGTQKVSFSGQ 442
+ SSG + ++ ++ + + SG ST T SE S + +
Sbjct: 334 ESSTTSSGASTATNSESSTTSSGASTATNSGSST--TSSGTSTATNSESSTVSSGASTAT 391
Query: 443 PQNITTEMTGPNNTTNFMTSSLPNSGS-VQNNELPSSNTGAWRVSTMNHPQMQAPSGMNG 501
+T +G + TN +S++ + S N+E ++++GA + A SG
Sbjct: 392 TSESSTTSSGASTATNSESSTVSSGASTATNSESSTTSSGANTATNSGSSVTSAGSGTAA 451
Query: 502 TSLSHLSN-------GESKSGGS 517
+ H ++ E+K GGS
Sbjct: 452 LTGMHTTSHSASTAVSEAKPGGS 474
Score = 52.0 bits (123), Expect = 6e-06
Identities = 75/362 (20%), Positives = 149/362 (41%), Gaps = 29/362 (8%)
Query: 191 NSKNQSDINHSTSGSHYENSQRGPVSST---SDSSTNCKNAVVSDLSEKEAWPS--APGS 245
NS++ + + +++ ++ E+S +ST SDSST A + S+ S + +
Sbjct: 107 NSESSTTSSGASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEASTAT 166
Query: 246 DPELASECMDADSASSSESERNITIMASGNTGGEKDGLRNSTGLGSQNKFVVGSSSNNVG 305
+ E ++ A +A++SES T+ + +T + S+G + ++SN G
Sbjct: 167 NSESSTTSSGASTATNSESS---TVSSRASTATNSESSTTSSGASTATNSESRTTSNGAG 223
Query: 306 HGSSTGPWGFSHGAIISTCQVSVDAPESKSESSNNRMNAWGTVSSSSNGGLNPSTLNSAS 365
+++ S GA +T S P S + ++ N ++ ++SS G ++ +S
Sbjct: 224 TATNSESSTTSSGASTATNSES-STPSSGAGTATNSESS----TTSSGAGTATNSESSTV 278
Query: 366 NHGAWPVLENNGLALKGPVGSGSSGINIQCSTIGQMPNN--QSINSKVSGGSTHGTWGSL 423
+ G V + P ++ N + ST N S +S S G++ T
Sbjct: 279 SSGISTVTNSESST---PSSGANTATNSESSTTSSGANTATNSDSSTTSSGASTAT---- 331
Query: 424 QETCESEVSGTQKVSFSGQPQNITTEMTGPNNTTNFMTSSLPNSGSVQNNELPSSNTGAW 483
SE S T + + +T +G + TN +S+ + S N S+ +
Sbjct: 332 ----NSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGA 387
Query: 484 RVSTMNHPQMQAPSGMNGTS--LSHLSNGESKSGGSYGTTWGAYGSNYSGDKCSGPNGQA 541
+T + + T+ S +S+G S + S +T + G+N + + S
Sbjct: 388 STATTSESSTTSSGASTATNSESSTVSSGASTATNSESSTTSS-GANTATNSGSSVTSAG 446
Query: 542 NG 543
+G
Sbjct: 447 SG 448
>gi|239757861 PREDICTED: similar to armadillo repeat containing,
X-linked 4 [Homo sapiens]
Length = 2382
Score = 62.4 bits (150), Expect = 4e-09
Identities = 190/930 (20%), Positives = 301/930 (32%), Gaps = 179/930 (19%)
Query: 375 NNGLALKGPVGSGSSG---INIQCSTIGQ--------MPNNQSINSKVSGGSTHGTWGSL 423
N + LK VG G+ G + I S+ G+ + N + SK G+ T GS+
Sbjct: 743 NPNVVLKAEVGEGAMGTAQLQIMASSKGEALLDSKNKVKGNSNAVSKAGAGTD--TTGSV 800
Query: 424 QE----TCESEVSGTQKVSFSGQPQNITTEMTGPNNTTNFMTSSLPNSGSVQNNELPSSN 479
Q + EV K G P + GP T + ++ NS Q LP +
Sbjct: 801 QPQIVANSQGEVLPGAKNKIRGNPTTVPNSGVGPYTTDSARPQAVANS---QGEVLPGAK 857
Query: 480 TGAWRVSTMNHPQMQAPSGMNGTSL--------SH---LSNGESKSGGSYGTTWGAYGSN 528
+V + +A +GM T SH L ++K G+ W A
Sbjct: 858 N---KVKANLNAVSKAEAGMGATGSVQPQAVANSHCETLPGAKNKVRGN----WNAVSKA 910
Query: 529 YSG-DKCSGPNGQANGDTVNATLMQPGVNGPMGTNFQVNTNKG------GGVWESGAANS 581
+G D QA ++ L PG + N V + G G A+S
Sbjct: 911 GAGMDTRGSAQPQAVANSQGEVL--PGAKNKVKGNPNVVSKAGAREDTVGSTQPQVLASS 968
Query: 582 QSTSW--------GSGNGANSGGSRR---GWGTP---AQNTGTNLPSVEWNKLPSNQHSN 627
Q + G+ N + G+R G P A + LP NK+ N ++
Sbjct: 969 QRETLPGARNKVKGNSNVVSKAGAREDTMGSAQPQVVANSQRETLPGAR-NKVKGNSNAI 1027
Query: 628 DSANGNGKTFTNGWKSTEEEDQGSATSQTNEQSSVWAKTGGTVESDGSTESTGRLEEKGT 687
A + QG ++ V + +++ ++ G + +
Sbjct: 1028 SKAEAGAGIMGSVQVQVVASFQGEVLP--GAKNKVRGNSNAVPKAEAGADTVGSAQPQAV 1085
Query: 688 GESQSRD----RRKIDQHTLL-----QSIVNRTDLDPRVLSNSGWGQTPIKQNTAWDT-- 736
SQS R K+ +T+ R P++++ S P ++ + T
Sbjct: 1086 ANSQSETLLGARNKVKGNTIAVPKAGTGAGTRHSAQPQIVAGSQGETLPGARDKSMSTSE 1145
Query: 737 -ETSPRGERKTDNGTEAWGSSATQTFNSGACIDKTSPNGNDTS----SVSGW-------- 783
E + E EA +S ++ + KT PN +D V W
Sbjct: 1146 AEATAEDEAYAKPEAEAMPTSESEGGSGTQACRKTQPNIHDYYWNGIGVEDWIAAERWIK 1205
Query: 784 -------GDPKPALRWGDSKGSNCQGGWEDDSAATGMVKS----------NQWGNCKEEK 826
GD + ++ W D + G W S G+++S W + E
Sbjct: 1206 FRFQTMDGDWENSVSWADDENEASIGSWSGASDKAGIIRSWAVACDETSVKSWAGARAEN 1265
Query: 827 ----AAWNDSQKNKQG--WGDGQKSSQGWSVSASDNWGETSRNNH-----W--------- 866
W + + G W GQ S W+ + T N W
Sbjct: 1266 VVGIGTWARAGEQASGGLWAGGQTSEGTWAGDKASGGAWTGAENQASGGSWALAGNQAIG 1325
Query: 867 -----GEANKKSSSGGSDSDRSVSGWNELGKTSSFTWGNNINPNNS---SGWDESSKPTP 918
G+A+ S GG S S G +G S+T N S +G S +
Sbjct: 1326 ELWAAGQASDGSWPGGQASGVSWVGEEAIG--GSWTGAENQASEGSWAGAGAGNMSSVSY 1383
Query: 919 SQGWGDPPKSNQSLGWGDSSKPVSSPDWNKQQDIVGSWGIPPATGKPPGTGWLGGPIPAP 978
G D G D S S P + Q GSW A G+ G LG P
Sbjct: 1384 WAGVVDQAGGGSWAGTSDQSGGGSKPRFEDQASGEGSWA--GAGGQASGGSMLG-----P 1436
Query: 979 AKEEEPTGWEEPSPESI--RRKMEIDDGT-SAW-------GDPSKYNYKNVNMWNKNVPN 1028
+ W + + ++ R +D + AW G SK ++N +
Sbjct: 1437 EDQSSGRSWADTADQASGGSRLGHVDQSSGGAWAGTLDQSGGGSKPRFENQTTEEGSWAG 1496
Query: 1029 GNSRSDQQAQVHQLLTPASAISNKEASSGSGWGEPWGEPSTP--ATTVDNGT-SAW---G 1082
++ S + ++ SSG W + S VD +W G
Sbjct: 1497 AGGQAG----------GGSKVGPEDQSSGRSWANSGDQISGGFLVGIVDQANGGSWTGAG 1546
Query: 1083 KPIDSGPSWGEPI--AAASSTSTWGSSSVGPQALSKSGPKSMQDGWCGDDMPLPGNRPTG 1140
P GP +PI S +W + S+ G ++D GD G++ +G
Sbjct: 1547 HPASVGP---KPIFEDQVSGRGSWADAREQVVGDSRLG---LRDQSSGDSWAGTGDQASG 1600
Query: 1141 WE---EEEDVEIGMWNSNSSQELNSSLNWP 1167
W G W S Q++ S P
Sbjct: 1601 WFCVCPGSQTNGGSWGGASGQDVGGSRPGP 1630
Score = 60.5 bits (145), Expect = 2e-08
Identities = 236/1104 (21%), Positives = 367/1104 (33%), Gaps = 232/1104 (21%)
Query: 159 AANLGSAVK--VLNSQSESS-ALTNQQPQNNGEVQNSKNQSDINHSTSGSHYENSQRGPV 215
A +GSA V NSQSE+ N+ N V + + HS SQ +
Sbjct: 1074 ADTVGSAQPQAVANSQSETLLGARNKVKGNTIAVPKAGTGAGTRHSAQPQIVAGSQGETL 1133
Query: 216 SSTSDSSTNCKNAVVSDLSEKEAWPSA---PGSDPELASECMDADSASSSESERNITIMA 272
D S + A + E A P A P S+ E S + + +++ NI
Sbjct: 1134 PGARDKSMSTSEAEATAEDEAYAKPEAEAMPTSESEGGS-----GTQACRKTQPNIHDYY 1188
Query: 273 SGNTGGEKDGLRNSTGLGSQNKFVVGSSSNNVG-----HGSSTGPW-GFSHGA-IISTCQ 325
G E D + + + + + G N+V + +S G W G S A II +
Sbjct: 1189 WNGIGVE-DWIAAERWIKFRFQTMDGDWENSVSWADDENEASIGSWSGASDKAGIIRSWA 1247
Query: 326 VSVDAPESKSESSNNRMNA-----WGTVSSSSNGGLNPSTLNSASNHGAWPVLENNGLAL 380
V+ D KS + N W ++GGL ++ G W + +G A
Sbjct: 1248 VACDETSVKSWAGARAENVVGIGTWARAGEQASGGL---WAGGQTSEGTWAGDKASGGAW 1304
Query: 381 KGPVGSGSSGINIQCSTIGQMPNNQSINSK-VSGGSTHGTWGSLQETCESEVSGTQKVSF 439
G S G + NQ+I +G ++ G+W + SG VS+
Sbjct: 1305 TGAENQASGGS-------WALAGNQAIGELWAAGQASDGSWPG------GQASG---VSW 1348
Query: 440 SGQPQNITTEMTGPNNTTNFMTSSLPNSGSVQNNELPSSNTGAWRVSTMNH--PQMQAPS 497
G+ + I TG N Q +E + GA +S++++ +
Sbjct: 1349 VGE-EAIGGSWTGAEN---------------QASEGSWAGAGAGNMSSVSYWAGVVDQAG 1392
Query: 498 GMNGTSLSHLSNGESK----SGGSYGTTWGAYGSNYSGDKCSGPNGQANGDTVNATLMQP 553
G + S S G SK S +W G SG GP Q++G + T Q
Sbjct: 1393 GGSWAGTSDQSGGGSKPRFEDQASGEGSWAGAGGQASGGSMLGPEDQSSGRSWADTADQA 1452
Query: 554 GVNGPMGTNFQVNTNKGGGVW-----ESGAAN--------SQSTSWGSGNGANSGGSRRG 600
+G Q GG W +SG + ++ SW G GGS+ G
Sbjct: 1453 SGGSRLGHVDQ----SSGGAWAGTLDQSGGGSKPRFENQTTEEGSWAGAGGQAGGGSKVG 1508
Query: 601 WGTPAQNTGTNLPSVEWNKLPSNQHSNDSANGNGKTFTNGWKSTEEEDQGSATSQTNEQS 660
P +Q S S W ++ ++ G +Q+
Sbjct: 1509 --------------------PEDQSSGRS-----------WANSGDQISGGFLVGIVDQA 1537
Query: 661 SVWAKTGGTVESDGSTESTGR---LEEKGTGESQSRDRRKIDQHTLLQSIVNRTDLDPRV 717
+ GG+ G S G E++ +G D R + +V + L R
Sbjct: 1538 N-----GGSWTGAGHPASVGPKPIFEDQVSGRGSWADAR--------EQVVGDSRLGLRD 1584
Query: 718 LSNS-GWGQTPIKQNTAWDTETSPRGERKTDNGTEAWGSSATQTFNSGACIDKTSPNGND 776
S+ W T Q + W P + T+ G+ WG + SG + + P +
Sbjct: 1585 QSSGDSWAGTG-DQASGWFC-VCPGSQ--TNGGS--WGGA------SGQDVGGSRPGPTN 1632
Query: 777 TSSVSGWGDPKPALRWGDSKGSNCQGGWEDDSAATGMVKSNQWGNCKEEKAAWNDSQKNK 836
SS W DS GS G S TG +Q G C +K
Sbjct: 1633 QSSAGSW----------DSPGSQVSG-----SCWTGAGAVDQAGGC------------SK 1665
Query: 837 QGWGDGQKSSQGWSVSASDNWGETSRNNHWGEANKKSSSGGSDSDRSVSGWNELGKTSSF 896
G+ D Q G+ A D G SR G D + W G
Sbjct: 1666 PGFED-QAIGGGFWPGAGDQTGGGSR------------PGSEDQSSGIGSWGVAG----- 1707
Query: 897 TWGNNINPNNSSGWDESSKPTPSQGWGDPPKSNQSLGWGDSSKPVSSPDWNKQQDIVGSW 956
G + D+SS + + G G+ +G GD + S P++ Q GSW
Sbjct: 1708 --GQVLGGARPGPADQSSGGSWA-GTGNQSSGRSWIGPGDQAVDCSKPEFEDQACGGGSW 1764
Query: 957 GIPPA-------TGKPPGTGWLGGPIPAPAKEEEPTG--W---EEPSPESIRRKMEIDDG 1004
+ G PG +GG E++ TG W E+ + + E++
Sbjct: 1765 AGAGSQASGESWAGSRPGNEAIGG--SRMGSEDQATGGSWARSEDQASGRFQVSFEVEAN 1822
Query: 1005 TSAWGDPSKYNYKNVNMWNKNVPNGNSRSDQQAQV---------HQLLTPASAISNKEAS 1055
W P W + + SR D + + + + + + +AS
Sbjct: 1823 EGFWFGPGAEAVIGSWCWTEEKADIVSRPDDKDEATTASRSRAGEEAMICSRIEAENKAS 1882
Query: 1056 SGSGWGEPWGEPSTPATTVDNGTSAWGKPIDSGPSWGEPIAAASSTSTWGSSSVGPQALS 1115
SGS W E + + G +G G A + + GP S
Sbjct: 1883 SGS-WIR--SEEVAYMGSCVGAEAGAGAEAGAGAEAGAGAGAEAGAEAGAGAGAGPGTES 1939
Query: 1116 KSGPKSMQDGWCGDDMPLPGNRPTG-------WEEEEDV---EIGMWNSNSSQELN-SSL 1164
+G S W GD + G W +V E+ +S +E++ SL
Sbjct: 1940 GAGVWS----WDGDATTVESRLGAGEEAGVESWTLARNVGEDELSRESSPDIEEISLRSL 1995
Query: 1165 NWPPYTKKMSSKGLSGKKRRRERG 1188
W + + SGK E G
Sbjct: 1996 FWAESENSNTFRSKSGKDASFESG 2019
>gi|110347429 mediator complex subunit 12 [Homo sapiens]
Length = 2177
Score = 61.2 bits (147), Expect = 9e-09
Identities = 41/93 (44%), Positives = 52/93 (55%), Gaps = 14/93 (15%)
Query: 93 QQPQQQQQQQQPQQQQPQQQPQPQPQQQQPQQQPQALPRYPR-EVPPRFRHQEHKQLLKR 151
+Q QQQQQQQQ QQQQ QQQ Q Q QQ Q QQQ QA P P+ + P+F+ Q +Q ++
Sbjct: 2089 RQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQ 2148
Query: 152 GQHFPVIAANLGSAVKVLNSQSESSALTNQQPQ 184
Q + V+ L Q L+N QPQ
Sbjct: 2149 QQ--------TAALVRQLQQQ-----LSNTQPQ 2168
Score = 50.8 bits (120), Expect = 1e-05
Identities = 34/131 (25%), Positives = 60/131 (45%), Gaps = 15/131 (11%)
Query: 8 ATKDVERNLSRDLVQEEEQLMEEKKKKKDDKKKKEAAQKKATEQKIKVPEQIKPSVSQPQ 67
+ + V+ + + E+Q +++++++ +++++ Q++ + I+ +Q + Q Q
Sbjct: 2034 SAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQ 2093
Query: 68 PANSNNGTSTATSTNNNAKRATANNQQPQQQQQQQQPQQQQPQQQPQPQP-------QQQ 120
++ QQ QQ QQQQQ Q PQ QPQ QP QQ
Sbjct: 2094 QQQQQQ--------QQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQT 2145
Query: 121 QPQQQPQALPR 131
Q QQQ AL R
Sbjct: 2146 QQQQQTAALVR 2156
Score = 45.1 bits (105), Expect = 7e-04
Identities = 34/113 (30%), Positives = 45/113 (39%), Gaps = 2/113 (1%)
Query: 1369 PLLSPQVPVSLLKYAPNNGGLNPLFGPQQVAMLNQLSQLNQLSQISQLQRLLAQQQRAQS 1428
P++S P+S G + P+Q Q Q Q Q Q Q+ Q Q
Sbjct: 2025 PMISTMTPMSA--QGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQ 2082
Query: 1429 QRSVPSGNRPQQDQQGRPLSVQQQMMQQSRQLDPNLLVKQQTPPSQQQPLHQP 1481
Q+ + QQ QQ + QQQ QQ +Q +QQ P Q QP QP
Sbjct: 2083 QQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQP 2135
Score = 42.4 bits (98), Expect = 0.005
Identities = 33/107 (30%), Positives = 46/107 (42%), Gaps = 8/107 (7%)
Query: 1394 GPQQVAMLNQLSQLNQLSQISQLQRLLAQQQRAQSQRSVPSGNRPQQDQQGRPLSVQQQM 1453
G + A+L + Q Q Q Q Q+ QQQ+ Q Q + R QQ QQ QQQ
Sbjct: 2041 GVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHI----RQQQQQQILRQQQQQQQ 2096
Query: 1454 MQQSRQLDPNLLVKQQTPPSQQQPLHQPAMKSFLDNVMPHTTPELQK 1500
QQ +Q +QQ QQQ Q ++ P + P+ Q+
Sbjct: 2097 QQQQQQQQQ----QQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQR 2139
Score = 38.1 bits (87), Expect = 0.085
Identities = 27/112 (24%), Positives = 52/112 (46%), Gaps = 6/112 (5%)
Query: 22 QEEEQLMEEKKKKKDDKKKKEAAQKKATEQKIKVPEQIKPSVSQPQPANSNNGTSTATST 81
Q+++Q +++++++ ++++ +++ +Q ++ +Q + Q Q
Sbjct: 2057 QQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQH 2116
Query: 82 NNNAKRATANNQ-QPQQQQQQQQPQQQQPQQQPQP-----QPQQQQPQQQPQ 127
++ A Q QPQ Q Q Q+ QQ QQQ Q Q QQQ QPQ
Sbjct: 2117 QQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQPQ 2168
Score = 37.7 bits (86), Expect = 0.11
Identities = 29/92 (31%), Positives = 39/92 (42%), Gaps = 3/92 (3%)
Query: 1396 QQVAMLNQLSQLNQLSQISQLQRLLAQQQRAQSQRSVPSGNRPQQDQQGRPLSVQQQMMQ 1455
QQ+ Q Q Q Q Q Q+ QQQ+ Q+ PQ Q +P +Q + Q
Sbjct: 2085 QQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQ 2144
Query: 1456 QSRQLDPNLLVKQ-QTPPSQQQPLHQPAMKSF 1486
+Q LV+Q Q S QP QP+ F
Sbjct: 2145 TQQQQQTAALVRQLQQQLSNTQP--QPSTNIF 2174
Score = 37.0 bits (84), Expect = 0.19
Identities = 45/175 (25%), Positives = 66/175 (37%), Gaps = 20/175 (11%)
Query: 1344 PRGMQQPPA---QPLSSSQPNLRAQVPPPLLSPQVPVS--LLKYAPNNGGLNPLFGPQQV 1398
P G PP+ QP S+ P+ + P Q S + + AP G + L Q+
Sbjct: 1959 PAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYG--HGLTSTQRF 2016
Query: 1399 AMLNQLSQLNQLSQISQLQRLLAQ--QQRAQSQRSVPSGNRPQQDQQGRPLSVQQQMMQQ 1456
+ L Q IS + + AQ Q +S +P + QQ QQ + QQQ QQ
Sbjct: 2017 SH----QTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQ 2072
Query: 1457 SRQL-------DPNLLVKQQTPPSQQQPLHQPAMKSFLDNVMPHTTPELQKGPSP 1504
+Q +L +QQ QQQ Q + H + Q+ P
Sbjct: 2073 QQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPP 2127
Score = 33.1 bits (74), Expect = 2.7
Identities = 26/101 (25%), Positives = 45/101 (44%), Gaps = 28/101 (27%)
Query: 22 QEEEQLMEEKKKKKDDKKKKEAAQKKATEQKIKVPEQIKPSVSQPQPANSNNGTSTATST 81
Q+++Q +++++++ +++++ Q + +Q+ P Q +P SQPQ
Sbjct: 2092 QQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQ-SQPQ-------------- 2136
Query: 82 NNNAKRATANNQQPQQQQQQQQP-----QQQQPQQQPQPQP 117
Q QQ QQQQQ Q QQ QPQP
Sbjct: 2137 --------FQRQGLQQTQQQQQTAALVRQLQQQLSNTQPQP 2169
Score = 32.0 bits (71), Expect = 6.1
Identities = 26/101 (25%), Positives = 44/101 (43%), Gaps = 5/101 (4%)
Query: 58 QIKPS--VSQPQPANSNNGTSTATSTNNNAKRATANNQQPQQQQQQQQPQQQQPQQQPQP 115
Q +PS V Q P + TST ++ ++ + Q Q + P+
Sbjct: 1992 QQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQ 2051
Query: 116 QPQQQQPQQQPQALPRYPREVPPR---FRHQEHKQLLKRGQ 153
Q QQQQ QQQ Q + ++ + R Q+ +Q+L++ Q
Sbjct: 2052 QQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQ 2092
>gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]
Length = 2063
Score = 58.5 bits (140), Expect = 6e-08
Identities = 38/90 (42%), Positives = 48/90 (53%), Gaps = 5/90 (5%)
Query: 53 IKVPEQIKPSVSQPQPANSNNGTSTATSTN--NNAKRATANNQQPQQQQQQQQPQQQQPQ 110
+ + +Q PS S P + S N N + QQ QQQQQQQQ QQQQ Q
Sbjct: 224 LHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQ 283
Query: 111 QQPQPQPQQQQPQQQPQAL-PRY--PREVP 137
QQ Q +P QQ QQQPQ + P++ P +VP
Sbjct: 284 QQLQARPPQQHQQQQPQGIRPQFTAPTQVP 313
Score = 54.7 bits (130), Expect = 9e-07
Identities = 116/490 (23%), Positives = 180/490 (36%), Gaps = 84/490 (17%)
Query: 38 KKKKEAAQKKATEQKIKVP--------EQIKPSVSQPQPANSNNGTSTATSTNNNA---- 85
KKKK +KK ++Q + P E +P + Q N +N +N
Sbjct: 915 KKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINLDNSGPKLPEFSNRPPGYP 974
Query: 86 -----------------KRATANNQQPQQQQQQQQPQQQQPQQQPQPQPQQQQPQQQPQA 128
+ Q PQQQ Q Q PQQQQP QPQ QQQQ QQQ
Sbjct: 975 SQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMM 1034
Query: 129 LPRYPREVPPRFR-------HQEHKQLLKRGQHFPVIAANLGSAVKVLNSQSESSALTNQ 181
+ ++ P R H L Q P+ GS +++ Q +S +
Sbjct: 1035 MMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPM--QQSGSVPVMVSLQGPASVPPSP 1092
Query: 182 QPQNNGEVQNSKNQSDINHSTSGSHYENSQRGPVSSTSDSSTNCKNAVVSDLSEKEAWPS 241
Q N + + ++ Y+ S + P SS + A + + S EA PS
Sbjct: 1093 DKQRMPMPVN----TPLGSNSRKMVYQESPQNP-----SSSPLAEMASLPEASGSEA-PS 1142
Query: 242 APGSDPELASECMDADSASSSESERNITIMASGNTGGEKDGLRNSTGLGSQNKFVVGSSS 301
PG + S + + +M +G G ++T + + V S
Sbjct: 1143 VPGGPNNMPSHVVLPQN----------QLMMTGPKPGPSP--LSATQGATPQQPPVNSLP 1190
Query: 302 NNVGH--GSSTGPWGFSHGAIISTCQVSVDAPESKSESSNNRMNAWGTVSSSSNGGLNPS 359
++ GH + P S + P ++ NNR + + S L+P
Sbjct: 1191 SSHGHHFPNVAAPTQTSRPKTPNRASPRPYYP----QTPNNRPPS----TEPSEISLSPE 1242
Query: 360 TLNSASNHGAWPVLENNGLALKGPVGSG--SSGIN-IQCSTIGQMPNNQSIN-SKVSGGS 415
LN AS G +P N L + + G G+N IGQ P+N ++N S +
Sbjct: 1243 RLN-ASIAGLFPPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQ 1301
Query: 416 THGTWGSLQETCESEVSG-TQKVSFSGQPQNI------TTEMTGPNNT--TNFMTSSLPN 466
TH + + + SG T++ S S ++ TT G N+ +S N
Sbjct: 1302 THKLDSVVVNSGKQSNSGATKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTN 1361
Query: 467 SGSVQNNELP 476
+ +QN ELP
Sbjct: 1362 AALLQNVELP 1371
Score = 48.1 bits (113), Expect = 8e-05
Identities = 84/356 (23%), Positives = 130/356 (36%), Gaps = 57/356 (16%)
Query: 1323 LNSVRQNGNPSMFGVGN----TAAQPRGMQQPPAQPLSSSQ----PNLRAQVPPPLLSPQ 1374
+N ++ + + FGV N T A ++PP + +S Q P+ R P
Sbjct: 888 VNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPP 947
Query: 1375 VPVSLLKYAPNNGGLNPLFGPQQVAMLNQLSQLNQLSQIS-QLQRLLAQQQRAQSQRSVP 1433
+P N+G P F + +Q + L Q+ QL + +A + Q+ P
Sbjct: 948 LPGEQGINLDNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQ--P 1005
Query: 1434 SGNRPQQDQQGRPLSVQQQMMQQSRQLDPNLLVKQQ--------------------TPPS 1473
PQQ Q P Q Q QQ +Q +L+ QQ P S
Sbjct: 1006 QPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDS 1065
Query: 1474 QQQPLHQ----PAMKSFLDNVMPHTTPELQKGPSPINAFSNFPIGLNSNLNVNMDMNSIK 1529
Q+ P+ Q P M S +P+ Q+ P P+N P+G NS V + S +
Sbjct: 1066 QRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNT----PLGSNSRKMVYQE--SPQ 1119
Query: 1530 EPQSR-LRKWTTVDSISVNTSLD-----QNSSKHGAISSGFRLEESPFVPYDFMNSSTSP 1583
P S L + ++ S + + N H + + P P S+T
Sbjct: 1120 NPSSSPLAEMASLPEASGSEAPSVPGGPNNMPSHVVLPQNQLMMTGP-KPGPSPLSATQG 1178
Query: 1584 ASP--------PGSIGDGWPRAKSPNGSSSVNWPPEFRPGEPWKGYP-NIDPETDP 1630
A+P P S G +P +P +S P P + P N P T+P
Sbjct: 1179 ATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEP 1234
Score = 47.4 bits (111), Expect = 1e-04
Identities = 99/448 (22%), Positives = 158/448 (35%), Gaps = 59/448 (13%)
Query: 1324 NSVRQN-GNPSMFGVGNTAAQ-PRGMQQPPAQPLSSSQPNLRAQVPPPLLSPQVP----- 1376
NSVR G P G G P + PP +SSS + A P P L P+ P
Sbjct: 157 NSVRMEAGFPMASGPGIIRMNNPATVMIPPGGNVSSS---MMAPGPNPELQPRTPRPASQ 213
Query: 1377 ----------VSLLKYAPNNGGLNPLFGPQQVAMLNQLSQLNQLSQISQLQRLLAQQQRA 1426
+ + + + +G L P P Q +N+ Q+N + QLQ+ QQQ+
Sbjct: 214 SDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNR--QMNP-ANFPQLQQQQQQQQQQ 270
Query: 1427 QSQRSVPSGNRPQQDQQGRPLSVQQQMMQQSRQLDPNLLVKQQ--TPPSQQQ----PLHQ 1480
Q Q+ + QQ Q RP QQ QQ + + P Q PP Q L
Sbjct: 271 QQQQQQQQQQQQQQQLQARP--PQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQP 328
Query: 1481 PAMKSFLDNVMPHTTPELQKGPSPINAFSNFPIGLNSNLNVNMDMNSIKEPQSRLRKWT- 1539
P + L + + + P P + L + +++ P +
Sbjct: 329 PPAQGSLGTMTANQGWKKAPLPGP----------MQQQLQARPSLATVQTPSHPPPPYPF 378
Query: 1540 -TVDSISVNTSLDQNSSKHGAISSGFR-LEESPF-VPYDFMN---SSTSPASPPGSIGDG 1593
+ + +T+ Q S+ + + L+ P VP ++ SPAS P S G
Sbjct: 379 GSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQG 438
Query: 1594 WPRAKSPNGSSSVNW----PPEFRPGEPWKGYPNIDPETDPYVTPGSVINNLSINTVREV 1649
P A SP + + PP+ P P P +P V G+V N + +
Sbjct: 439 SP-ASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPP 497
Query: 1650 DHLRDRNSGSSSSLNTTLPSTSAWSSIRASNYNVPLSSTAQSTSARNSDSKLTWSPGSVT 1709
+ + LP + + + ST +T + +P
Sbjct: 498 NQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATTPGNSG------APQLQA 551
Query: 1710 NTSLAHELWKVPLPPKNITAPSRPPPGL 1737
N ++ H + PP+N S PP +
Sbjct: 552 NQNVQHAGGQGAGPPQNQMQVSHGPPNM 579
Score = 38.9 bits (89), Expect = 0.050
Identities = 37/134 (27%), Positives = 56/134 (41%), Gaps = 14/134 (10%)
Query: 22 QEEEQLMEEKKKKKDDKKKKEAAQKKATEQKIKVP---EQIKPSVSQPQPANSNNGTSTA 78
Q+++QL ++ ++ + + ++ VP Q+ QP PA + GT TA
Sbjct: 281 QQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTA 340
Query: 79 TSTNNNAKRATANNQQPQQQQQQQQPQ---QQQPQQQPQPQPQQQQPQQQPQALPRYPR- 134
N K+A P QQQ Q +P Q P P P P QQ QA +P+
Sbjct: 341 ---NQGWKKAPLPG--PMQQQLQARPSLATVQTPSHPPPPYPFGS--QQASQAHTNFPQM 393
Query: 135 EVPPRFRHQEHKQL 148
P +F + K L
Sbjct: 394 SNPGQFTAPQMKSL 407
Score = 38.5 bits (88), Expect = 0.065
Identities = 72/330 (21%), Positives = 125/330 (37%), Gaps = 57/330 (17%)
Query: 1297 SMKLPPSNSALPN-QALGSIA-GLGMQNLNSVRQNGNPSMFGVGNTAAQPRGMQQPPAQP 1354
++ + PSN A P L S+ G Q+ + + +PS + + + P Q
Sbjct: 1289 NLTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRRSSPGSSRKTTPSPGRQN 1348
Query: 1355 LSSSQPNLRAQV-----------------PPPLLSPQVPVSLLKYAPNNGGLNPLFGPQQ 1397
+ + L +Q P PL +P VP S PNN GLNP
Sbjct: 1349 SKAPKLTLASQTNAALLQNVELPRNVLVSPTPLANPPVPGSF----PNNSGLNPQNSTVS 1404
Query: 1398 VAMLNQLSQLNQLS----QISQLQRLLAQQQRAQSQ-RSVPSGNRPQQDQQGRPLSVQQQ 1452
VA + + + N+ S Q S Q +++++ + ++VP+ Q+ + + + Q
Sbjct: 1405 VAAVGGVVEDNKESLNVPQDSDCQNSQSRKEQVNIELKAVPA-------QEVKMVVPEDQ 1457
Query: 1453 MMQQSRQLDPNLLVKQQTPPSQQQPLHQPA---MKSFLDN-------VMPHTTPELQKGP 1502
+ + DPN L + + P + A + LDN + P +L+ P
Sbjct: 1458 SKKDGQPSDPNKLPSVEENKNLVSPAMREAPTSLSQLLDNSGAPNVTIKPPGLTDLEVTP 1517
Query: 1503 SPINAFSNFPIGLNSNLNVNMDMNSIKEPQSRLR--KWTTVDSISVNTSLDQNSSKHGAI 1560
+ S + S + D++S KEP + L + S V+ L + +
Sbjct: 1518 PVV---SGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLVHPELSE-------V 1567
Query: 1561 SSGFRLEESPFVPYDFMNSSTSPASPPGSI 1590
SS P + +SS S PP I
Sbjct: 1568 SSNVAPSIPPVMSRPVSSSSISTPLPPNQI 1597
Score = 37.7 bits (86), Expect = 0.11
Identities = 23/57 (40%), Positives = 28/57 (49%), Gaps = 3/57 (5%)
Query: 94 QPQQQQQQQQPQ---QQQPQQQPQPQPQQQQPQQQPQALPRYPREVPPRFRHQEHKQ 147
QP +Q P Q Q QQQ Q Q QQQQ QQQ Q + + PP+ Q+ Q
Sbjct: 244 QPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQ 300
Score = 35.0 bits (79), Expect = 0.72
Identities = 52/209 (24%), Positives = 76/209 (36%), Gaps = 28/209 (13%)
Query: 1291 QFMSSQSMKLPPSNSALPNQALGSIAGLGMQNLNSVRQN---------------GNPSMF 1335
QF + + +PP + LP+ AL G + Q PS+
Sbjct: 305 QFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLA 364
Query: 1336 GVGNTAAQPRGMQQPPAQPLSSSQPNLRAQVPPPLLSPQVPVSLLKYAPNNGGLNPLFGP 1395
V T + P PP P S Q + +A P +S + + GG + + P
Sbjct: 365 TV-QTPSHP-----PPPYPFGSQQAS-QAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTP 417
Query: 1396 QQVAMLNQLSQLNQLSQISQ----LQRLLAQQQRAQSQRSVPSGNRPQQDQQGRPLSVQQ 1451
Q L S + S Q + Q Q+ R + PQ QQ +
Sbjct: 418 LQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRN 477
Query: 1452 QMMQQSRQLDPNLLVKQQTPPSQ-QQPLH 1479
M+QQ + PN +V QQ PP+Q Q LH
Sbjct: 478 PMVQQGN-VPPNFMVMQQQPPNQGPQSLH 505
Score = 35.0 bits (79), Expect = 0.72
Identities = 41/167 (24%), Positives = 62/167 (37%), Gaps = 25/167 (14%)
Query: 54 KVPEQIK-PSVSQPQPANS----NNGTSTATSTNNNAK-----RATANNQQPQQQQQQ-- 101
+VP ++ P ++ PA+S G+ ++ T N + R NN PQ QQ
Sbjct: 413 RVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVS 472
Query: 102 ---QQPQQQQPQQQP-----QPQPQQQQPQQQPQALPRYPREVPPRFRHQEHKQLLKRGQ 153
+ P QQ P Q QP Q PQ L P+ +PP F + +GQ
Sbjct: 473 SPGRNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQ 532
Query: 154 HFPVIAANLGSAVKVLNSQSESSALTNQQPQNNGEVQNSKNQSDINH 200
A G+ + + A N Q +NQ ++H
Sbjct: 533 VPSTTATTPGN-----SGAPQLQANQNVQHAGGQGAGPPQNQMQVSH 574
Score = 33.5 bits (75), Expect = 2.1
Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 8/86 (9%)
Query: 56 PEQIKPSVSQPQPANSNNGTSTATSTNNNAKRATANNQQPQQQQQQQQPQQQQPQQQPQP 115
P ++ + QP N S A+S ++ + + A++ Q QQQ P+ PQ P P
Sbjct: 411 PSRVPTPLQQPHLTNK----SPASSPSSFQQGSPASSPTVNQTQQQMGPRP--PQNNPLP 464
Query: 116 QPQQQQPQQQPQALPRYPR-EVPPRF 140
Q QQP P P + VPP F
Sbjct: 465 Q-GFQQPVSSPGRNPMVQQGNVPPNF 489
Score = 32.7 bits (73), Expect = 3.6
Identities = 61/241 (25%), Positives = 82/241 (34%), Gaps = 47/241 (19%)
Query: 1257 KGPGSRPQISKESSMERNPYFDKDGIVADESQNMQFMSSQSMKLPPSNSALPNQALGSIA 1316
K P S P ++ S +P + Q Q M + PP N+ LP ++
Sbjct: 426 KSPASSPSSFQQGSPASSPTVN---------QTQQQMGPR----PPQNNPLPQGFQQPVS 472
Query: 1317 GLGMQNLNSVRQNGNPSMFGVGNTAAQPRGMQQPPAQPLSSSQPNL------------RA 1364
G + V+Q P F V QQPP Q S P L
Sbjct: 473 SPGRNPM--VQQGNVPPNFMVMQ--------QQPPNQGPQSLHPGLGGMPKRLPPGFSAG 522
Query: 1365 QVPPPLLSPQVPVSLLKYAPNNGGLNPLFGPQQVAMLNQLSQLNQLSQISQLQRLLAQQQ 1424
Q P + QVP S P N G PQ A N Q + Q Q ++
Sbjct: 523 QANPNFMQGQVP-STTATTPGNSG-----APQLQANQNVQHAGGQGAGPPQNQMQVSHGP 576
Query: 1425 RAQSQRSVPSGNRPQQDQQGRPLSVQQQMMQQSRQLDPNLLVKQQTPPSQQQPLHQPAMK 1484
Q S+ + +QQ V Q + + Q P QQ PPSQ +HQ +
Sbjct: 577 PNMMQPSLMGIHGNMNNQQAGTSGVPQVNLS-NMQGQP-----QQGPPSQLMGMHQQIVP 630
Query: 1485 S 1485
S
Sbjct: 631 S 631
Score = 31.6 bits (70), Expect = 8.0
Identities = 44/163 (26%), Positives = 63/163 (38%), Gaps = 28/163 (17%)
Query: 61 PSVSQPQPANSNNGTSTATSTNNNAKRATANNQQPQQQQ----------QQQQPQQ-QQP 109
P++ QP + + + + + +N Q Q QQ QQ P Q Q
Sbjct: 577 PNMMQPSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMV 636
Query: 110 QQQPQPQPQ--------QQQPQQQPQALPRYPREVPPRFRHQEHKQLLKRGQHFPVIAA- 160
QQQ PQ Q PQ Q P P R KQ+L Q P + A
Sbjct: 637 QQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQNLGPSPQRMTPPKQML--SQQGPQMMAP 694
Query: 161 ---NLGSAVKVLNSQSE--SSALTNQQPQNNGEVQNSKNQSDI 198
+G +VL Q+ +TNQ Q N + N++NQS++
Sbjct: 695 HNQMMGPQGQVLLQQNPMIEQIMTNQM-QGNKQQFNTQNQSNV 736
>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
Length = 715
Score = 58.2 bits (139), Expect = 8e-08
Identities = 30/55 (54%), Positives = 36/55 (65%)
Query: 93 QQPQQQQQQQQPQQQQPQQQPQPQPQQQQPQQQPQALPRYPREVPPRFRHQEHKQ 147
QQ QQQQQQQQ QQQQ QQQ Q Q QQQQ QQQ Q ++P + + Q+ +Q
Sbjct: 153 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQ 207
Score = 56.6 bits (135), Expect = 2e-07
Identities = 31/61 (50%), Positives = 37/61 (60%)
Query: 93 QQPQQQQQQQQPQQQQPQQQPQPQPQQQQPQQQPQALPRYPREVPPRFRHQEHKQLLKRG 152
QQ QQQQQQQQ QQQQ QQQ Q Q QQQQ QQQ Q ++ + + Q+ +Q L
Sbjct: 154 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQ 213
Query: 153 Q 153
Q
Sbjct: 214 Q 214
Score = 54.3 bits (129), Expect = 1e-06
Identities = 32/78 (41%), Positives = 40/78 (51%)
Query: 50 EQKIKVPEQIKPSVSQPQPANSNNGTSTATSTNNNAKRATANNQQPQQQQQQQQPQQQQP 109
+Q++ P+Q++ + Q Q + QQ QQQQQQQQ QQQQ
Sbjct: 109 QQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQ 168
Query: 110 QQQPQPQPQQQQPQQQPQ 127
QQQ Q Q QQQQ QQQ Q
Sbjct: 169 QQQQQQQQQQQQQQQQQQ 186
Score = 53.5 bits (127), Expect = 2e-06
Identities = 53/205 (25%), Positives = 89/205 (43%), Gaps = 20/205 (9%)
Query: 20 LVQEEEQLMEEKKKKKDDKKKKEAAQKKATEQKIKVPEQIKPSVSQPQPANSNNGTSTAT 79
L Q++ ++++++ ++ KK++E + +Q+ + +Q + Q Q
Sbjct: 122 LQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQ------------ 169
Query: 80 STNNNAKRATANNQQPQQQQQQQQPQQQQPQQQPQPQPQQQQPQQQPQALPRYPREVPPR 139
++ QQ QQQQQQQQ QQQ P +Q + Q QQQQ QQQ A ++ +
Sbjct: 170 ------QQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQ 223
Query: 140 FRHQEHKQLLKRGQHFPVIAANLGSAVKVLNS--QSESSALTNQQPQNNGEVQNSKNQSD 197
+ + +Q L Q +I+ G A + S Q+ S QQ +S +
Sbjct: 224 MQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNG 283
Query: 198 INHSTSGSHYENSQRGPVSSTSDSS 222
I H NS S+TS +S
Sbjct: 284 IKHGGLDLTTNNSSSTTSSNTSKAS 308
Score = 49.3 bits (116), Expect = 4e-05
Identities = 68/235 (28%), Positives = 93/235 (39%), Gaps = 31/235 (13%)
Query: 1344 PRGMQQPPAQPLSSSQPNLRAQVPPPLLSPQVPVSLLKYAPNNGGLNPLFGPQQVAMLNQ 1403
P+ MQQ Q + S Q L+A LL Q V L + L + QQ + Q
Sbjct: 101 PQQMQQILQQQVLSPQ-QLQA-----LLQQQQAVMLQQQQ-----LQEFYKKQQEQLHLQ 149
Query: 1404 LSQLNQLSQISQLQRLLAQQQRAQSQRSVPSGNRPQQDQQ----GRPLSVQQQMMQQSRQ 1459
L Q Q Q Q Q+ QQQ+ Q Q+ + QQ QQ G+ QQQ QQ +Q
Sbjct: 150 LLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQ 209
Query: 1460 LDPNLLVKQQTPPSQQQPLHQPAMKSF----LDNVMP-------HTTPELQKGPSPINAF 1508
L LV QQ QQ Q + S L ++ P + P+ P+ I
Sbjct: 210 LAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQL 269
Query: 1509 SNFPIGLNSNLNVNMDMNSIKEPQSRLRKWTTVDSISVNTSLDQNSSKHGAISSG 1563
G++S M+ N IK L + + S NTS H +I +G
Sbjct: 270 WKEVTGVHS-----MEDNGIKHGGLDLTTNNSSSTTSSNTSKASPPITHHSIVNG 319
Score = 43.1 bits (100), Expect = 0.003
Identities = 73/309 (23%), Positives = 108/309 (34%), Gaps = 57/309 (18%)
Query: 1319 GMQNLNSVRQNGNPSMFGVGNTAAQPRGMQQPPAQPLSSSQPNLRAQVPPPLLSPQVPVS 1378
GM L+S G+ G+T+++ ++ L Q Q LL Q S
Sbjct: 19 GMSTLSSQLDAGSRDGRSSGDTSSEVSTVE------LLHLQQQQALQAARQLLLQQ-QTS 71
Query: 1379 LLKYAPNNGGLNPLFGPQQVAMLN-QLSQLNQLSQISQLQ-------------------- 1417
LK ++ PL P VAM+ Q+ Q+ QI Q Q
Sbjct: 72 GLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQ 131
Query: 1418 -----------------RLLAQQQRAQSQRSVPSGNRPQQDQQGRPLSVQQQMMQQSRQL 1460
+LL QQQ+ Q Q+ + QQ QQ + QQQ QQ +Q
Sbjct: 132 QQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 191
Query: 1461 DPNLLVKQQTPPSQQQPLHQPAMKSFLDNVMPHTTPELQKGPSPI--NAFSNFPIGLNSN 1518
P K+Q QQQ F ++ + Q+ + + P G +
Sbjct: 192 HPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPG-QAA 250
Query: 1519 LNVNMDMNSIKEPQSRLRKWTTVDSISVNTSLDQNSSKHGAISSGFRLEESPFVPYDFMN 1578
L V + P + W V + S++ N KHG + S +
Sbjct: 251 LPVQSLPQAGLSPAEIQQLWKEVTGVH---SMEDNGIKHGGLDLTTNNSSST------TS 301
Query: 1579 SSTSPASPP 1587
S+TS ASPP
Sbjct: 302 SNTSKASPP 310
Score = 40.0 bits (92), Expect = 0.022
Identities = 30/90 (33%), Positives = 39/90 (43%), Gaps = 23/90 (25%)
Query: 87 RATANNQQPQQ-----------------------QQQQQQPQQQQPQQQPQPQPQQQQPQ 123
+A QQ QQQQQQ QQQQ QQQ Q Q QQQQ Q
Sbjct: 119 QALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQ 178
Query: 124 QQPQALPRYPREVPPRFRHQEHKQLLKRGQ 153
QQ Q + ++ P + +E +Q ++ Q
Sbjct: 179 QQQQQQQQQQQQQHPGKQAKEQQQQQQQQQ 208
Score = 38.9 bits (89), Expect = 0.050
Identities = 51/217 (23%), Positives = 86/217 (39%), Gaps = 16/217 (7%)
Query: 20 LVQEEEQLMEEKKKKKDDKKKKEAAQKKATEQKIKVPEQIKPSVSQPQPANSNNGTSTAT 79
L+Q+++ +M ++++ ++ KK+ Q++ Q ++ +Q + Q Q
Sbjct: 121 LLQQQQAVMLQQQQLQEFYKKQ---QEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQ 177
Query: 80 STNNNAKRATANNQQPQQQ---QQQQQPQQQQPQQQP---QPQPQQQQPQQQPQALPRYP 133
++ Q P +Q QQQQQ QQQQ Q Q Q Q Q QQ Q L
Sbjct: 178 QQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQ 237
Query: 134 RE----VPPRFRHQEHKQLLKRGQHFPVIAANLGSAVKVLNSQSESSALTN--QQPQNNG 187
R+ +PP + L + G P L V ++S ++ NN
Sbjct: 238 RQGLISIPPGQAALPVQSLPQAGLS-PAEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNS 296
Query: 188 EVQNSKNQSDINHSTSGSHYENSQRGPVSSTSDSSTN 224
S N S + + N Q +S+ DSS++
Sbjct: 297 SSTTSSNTSKASPPITHHSIVNGQSSVLSARRDSSSH 333
Score = 33.9 bits (76), Expect = 1.6
Identities = 47/215 (21%), Positives = 78/215 (36%), Gaps = 31/215 (14%)
Query: 21 VQEEEQLMEEKKKKKDDKKKKEAAQKKATEQKIKVPEQIKPSVSQPQPANSNNGTSTATS 80
V ++Q ++E KK+ ++ + Q++ +Q+ + +Q + Q Q
Sbjct: 128 VMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 187
Query: 81 TNNNAKRATANNQQPQQQQQQQQP------------QQQQPQQQPQPQPQQQ-------- 120
A QQ QQQQQQQ QQ QQQ Q+Q
Sbjct: 188 QQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPG 247
Query: 121 QPQQQPQALPR---YPREVPPRFR-----HQEHKQLLKRGQHFPVIAANLGSAVKVLNSQ 172
Q Q+LP+ P E+ ++ H +K G + N S+ N+
Sbjct: 248 QAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGG--LDLTTNNSSSTTSSNTS 305
Query: 173 SESSALTNQQPQN-NGEVQNSKNQSDINHSTSGSH 206
S +T+ N V +++ S + T SH
Sbjct: 306 KASPPITHHSIVNGQSSVLSARRDSSSHEETGASH 340
Score = 32.7 bits (73), Expect = 3.6
Identities = 31/118 (26%), Positives = 42/118 (35%), Gaps = 16/118 (13%)
Query: 95 PQQQQQQQQPQQQQPQQQPQPQPQQQQPQQQPQALPRYPREVPPRFRHQEHKQLLKRGQH 154
PQQ QQ Q Q PQQ QQQ Q Q L +E + + Q H QLL++ Q
Sbjct: 101 PQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQL----QEFYKKQQEQLHLQLLQQQQQ 156
Query: 155 FPVIAANLGSAVKVLNSQSESSALTNQQPQNNGEVQNSKNQSDINHSTSGSHYENSQR 212
+ Q + QQ Q + Q + Q G + Q+
Sbjct: 157 ------------QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQ 202
>gi|22538413 forkhead box P2 isoform III [Homo sapiens]
Length = 623
Score = 58.2 bits (139), Expect = 8e-08
Identities = 30/55 (54%), Positives = 36/55 (65%)
Query: 93 QQPQQQQQQQQPQQQQPQQQPQPQPQQQQPQQQPQALPRYPREVPPRFRHQEHKQ 147
QQ QQQQQQQQ QQQQ QQQ Q Q QQQQ QQQ Q ++P + + Q+ +Q
Sbjct: 61 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQ 115
Score = 56.6 bits (135), Expect = 2e-07
Identities = 31/61 (50%), Positives = 37/61 (60%)
Query: 93 QQPQQQQQQQQPQQQQPQQQPQPQPQQQQPQQQPQALPRYPREVPPRFRHQEHKQLLKRG 152
QQ QQQQQQQQ QQQQ QQQ Q Q QQQQ QQQ Q ++ + + Q+ +Q L
Sbjct: 62 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQ 121
Query: 153 Q 153
Q
Sbjct: 122 Q 122
Score = 54.3 bits (129), Expect = 1e-06
Identities = 32/78 (41%), Positives = 40/78 (51%)
Query: 50 EQKIKVPEQIKPSVSQPQPANSNNGTSTATSTNNNAKRATANNQQPQQQQQQQQPQQQQP 109
+Q++ P+Q++ + Q Q + QQ QQQQQQQQ QQQQ
Sbjct: 17 QQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQ 76
Query: 110 QQQPQPQPQQQQPQQQPQ 127
QQQ Q Q QQQQ QQQ Q
Sbjct: 77 QQQQQQQQQQQQQQQQQQ 94
Score = 53.5 bits (127), Expect = 2e-06
Identities = 53/205 (25%), Positives = 89/205 (43%), Gaps = 20/205 (9%)
Query: 20 LVQEEEQLMEEKKKKKDDKKKKEAAQKKATEQKIKVPEQIKPSVSQPQPANSNNGTSTAT 79
L Q++ ++++++ ++ KK++E + +Q+ + +Q + Q Q
Sbjct: 30 LQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQ------------ 77
Query: 80 STNNNAKRATANNQQPQQQQQQQQPQQQQPQQQPQPQPQQQQPQQQPQALPRYPREVPPR 139
++ QQ QQQQQQQQ QQQ P +Q + Q QQQQ QQQ A ++ +
Sbjct: 78 ------QQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQ 131
Query: 140 FRHQEHKQLLKRGQHFPVIAANLGSAVKVLNS--QSESSALTNQQPQNNGEVQNSKNQSD 197
+ + +Q L Q +I+ G A + S Q+ S QQ +S +
Sbjct: 132 MQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNG 191
Query: 198 INHSTSGSHYENSQRGPVSSTSDSS 222
I H NS S+TS +S
Sbjct: 192 IKHGGLDLTTNNSSSTTSSNTSKAS 216
Score = 49.3 bits (116), Expect = 4e-05
Identities = 68/235 (28%), Positives = 93/235 (39%), Gaps = 31/235 (13%)
Query: 1344 PRGMQQPPAQPLSSSQPNLRAQVPPPLLSPQVPVSLLKYAPNNGGLNPLFGPQQVAMLNQ 1403
P+ MQQ Q + S Q L+A LL Q V L + L + QQ + Q
Sbjct: 9 PQQMQQILQQQVLSPQ-QLQA-----LLQQQQAVMLQQQQ-----LQEFYKKQQEQLHLQ 57
Query: 1404 LSQLNQLSQISQLQRLLAQQQRAQSQRSVPSGNRPQQDQQ----GRPLSVQQQMMQQSRQ 1459
L Q Q Q Q Q+ QQQ+ Q Q+ + QQ QQ G+ QQQ QQ +Q
Sbjct: 58 LLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQ 117
Query: 1460 LDPNLLVKQQTPPSQQQPLHQPAMKSF----LDNVMP-------HTTPELQKGPSPINAF 1508
L LV QQ QQ Q + S L ++ P + P+ P+ I
Sbjct: 118 LAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQL 177
Query: 1509 SNFPIGLNSNLNVNMDMNSIKEPQSRLRKWTTVDSISVNTSLDQNSSKHGAISSG 1563
G++S M+ N IK L + + S NTS H +I +G
Sbjct: 178 WKEVTGVHS-----MEDNGIKHGGLDLTTNNSSSTTSSNTSKASPPITHHSIVNG 227
Score = 40.0 bits (92), Expect = 0.022
Identities = 30/90 (33%), Positives = 39/90 (43%), Gaps = 23/90 (25%)
Query: 87 RATANNQQPQQ-----------------------QQQQQQPQQQQPQQQPQPQPQQQQPQ 123
+A QQ QQQQQQ QQQQ QQQ Q Q QQQQ Q
Sbjct: 27 QALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQ 86
Query: 124 QQPQALPRYPREVPPRFRHQEHKQLLKRGQ 153
QQ Q + ++ P + +E +Q ++ Q
Sbjct: 87 QQQQQQQQQQQQQHPGKQAKEQQQQQQQQQ 116
Score = 38.9 bits (89), Expect = 0.050
Identities = 51/217 (23%), Positives = 86/217 (39%), Gaps = 16/217 (7%)
Query: 20 LVQEEEQLMEEKKKKKDDKKKKEAAQKKATEQKIKVPEQIKPSVSQPQPANSNNGTSTAT 79
L+Q+++ +M ++++ ++ KK+ Q++ Q ++ +Q + Q Q
Sbjct: 29 LLQQQQAVMLQQQQLQEFYKKQ---QEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQ 85
Query: 80 STNNNAKRATANNQQPQQQ---QQQQQPQQQQPQQQP---QPQPQQQQPQQQPQALPRYP 133
++ Q P +Q QQQQQ QQQQ Q Q Q Q Q QQ Q L
Sbjct: 86 QQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQ 145
Query: 134 RE----VPPRFRHQEHKQLLKRGQHFPVIAANLGSAVKVLNSQSESSALTN--QQPQNNG 187
R+ +PP + L + G P L V ++S ++ NN
Sbjct: 146 RQGLISIPPGQAALPVQSLPQAGLS-PAEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNS 204
Query: 188 EVQNSKNQSDINHSTSGSHYENSQRGPVSSTSDSSTN 224
S N S + + N Q +S+ DSS++
Sbjct: 205 SSTTSSNTSKASPPITHHSIVNGQSSVLSARRDSSSH 241
Score = 36.2 bits (82), Expect = 0.32
Identities = 52/227 (22%), Positives = 76/227 (33%), Gaps = 49/227 (21%)
Query: 1400 MLNQLSQLNQLSQISQLQ-------------------------------------RLLAQ 1422
M Q+ Q+ QI Q Q +LL Q
Sbjct: 2 MTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQ 61
Query: 1423 QQRAQSQRSVPSGNRPQQDQQGRPLSVQQQMMQQSRQLDPNLLVKQQTPPSQQQPLHQPA 1482
QQ+ Q Q+ + QQ QQ + QQQ QQ +Q P K+Q QQQ
Sbjct: 62 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQ 121
Query: 1483 MKSFLDNVMPHTTPELQKGPSPI--NAFSNFPIGLNSNLNVNMDMNSIKEPQSRLRKWTT 1540
F ++ + Q+ + + P G + L V + P + W
Sbjct: 122 QLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPG-QAALPVQSLPQAGLSPAEIQQLWKE 180
Query: 1541 VDSISVNTSLDQNSSKHGAISSGFRLEESPFVPYDFMNSSTSPASPP 1587
V + S++ N KHG + S +S+TS ASPP
Sbjct: 181 VTGVH---SMEDNGIKHGGLDLTTNNSSST------TSSNTSKASPP 218
Score = 33.9 bits (76), Expect = 1.6
Identities = 47/215 (21%), Positives = 78/215 (36%), Gaps = 31/215 (14%)
Query: 21 VQEEEQLMEEKKKKKDDKKKKEAAQKKATEQKIKVPEQIKPSVSQPQPANSNNGTSTATS 80
V ++Q ++E KK+ ++ + Q++ +Q+ + +Q + Q Q
Sbjct: 36 VMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 95
Query: 81 TNNNAKRATANNQQPQQQQQQQQP------------QQQQPQQQPQPQPQQQ-------- 120
A QQ QQQQQQQ QQ QQQ Q+Q
Sbjct: 96 QQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPG 155
Query: 121 QPQQQPQALPR---YPREVPPRFR-----HQEHKQLLKRGQHFPVIAANLGSAVKVLNSQ 172
Q Q+LP+ P E+ ++ H +K G + N S+ N+
Sbjct: 156 QAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGG--LDLTTNNSSSTTSSNTS 213
Query: 173 SESSALTNQQPQN-NGEVQNSKNQSDINHSTSGSH 206
S +T+ N V +++ S + T SH
Sbjct: 214 KASPPITHHSIVNGQSSVLSARRDSSSHEETGASH 248
Score = 32.7 bits (73), Expect = 3.6
Identities = 31/118 (26%), Positives = 42/118 (35%), Gaps = 16/118 (13%)
Query: 95 PQQQQQQQQPQQQQPQQQPQPQPQQQQPQQQPQALPRYPREVPPRFRHQEHKQLLKRGQH 154
PQQ QQ Q Q PQQ QQQ Q Q L +E + + Q H QLL++ Q
Sbjct: 9 PQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQL----QEFYKKQQEQLHLQLLQQQQQ 64
Query: 155 FPVIAANLGSAVKVLNSQSESSALTNQQPQNNGEVQNSKNQSDINHSTSGSHYENSQR 212
+ Q + QQ Q + Q + Q G + Q+
Sbjct: 65 ------------QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQ 110
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.305 0.123 0.369
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 89,711,227
Number of Sequences: 37866
Number of extensions: 5047409
Number of successful extensions: 42754
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 361
Number of HSP's successfully gapped in prelim test: 723
Number of HSP's that attempted gapping in prelim test: 21904
Number of HSP's gapped (non-prelim): 10085
length of query: 1962
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1845
effective length of database: 13,817,196
effective search space: 25492726620
effective search space used: 25492726620
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.