Guide to the Human Genome
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Search of human proteins with 226497734

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|226497734 RNA binding motif protein 19 [Homo sapiens]
         (960 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|226497734 RNA binding motif protein 19 [Homo sapiens]             1907   0.0  
gi|226497654 RNA binding motif protein 19 [Homo sapiens]             1907   0.0  
gi|226497574 RNA binding motif protein 19 [Homo sapiens]             1907   0.0  
gi|187960109 RNA binding motif protein 28 [Homo sapiens]               92   2e-18
gi|14110420 heterogeneous nuclear ribonucleoprotein D isoform a ...    83   1e-15
gi|14110414 heterogeneous nuclear ribonucleoprotein D isoform c ...    83   1e-15
gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens]      82   2e-15
gi|14110417 heterogeneous nuclear ribonucleoprotein D isoform b ...    81   4e-15
gi|51477708 heterogeneous nuclear ribonucleoprotein D isoform d ...    81   4e-15
gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Ho...    81   5e-15
gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo...    81   5e-15
gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Ho...    81   5e-15
gi|55956788 nucleolin [Homo sapiens]                                   80   7e-15
gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens]      80   9e-15
gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens]      78   5e-14
gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo s...    78   5e-14
gi|55956921 heterogeneous nuclear ribonucleoprotein A/B isoform ...    77   6e-14
gi|55956919 heterogeneous nuclear ribonucleoprotein A/B isoform ...    77   6e-14
gi|7661952 squamous cell carcinoma antigen recognized by T cells...    75   2e-13
gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo s...    74   7e-13
gi|74099697 heterogeneous nuclear ribonucleoprotein H2 [Homo sap...    74   7e-13
gi|9624998 heterogeneous nuclear ribonucleoprotein H2 [Homo sapi...    74   7e-13
gi|77695912 TIA-1 related protein isoform 2 [Homo sapiens]             73   1e-12
gi|5031753 heterogeneous nuclear ribonucleoprotein H1 [Homo sapi...    73   1e-12
gi|14110407 heterogeneous nuclear ribonucleoprotein D-like [Homo...    73   1e-12
gi|188219591 TIA1 protein isoform 2 [Homo sapiens]                     72   2e-12
gi|148470406 heterogeneous nuclear ribonucleoprotein F [Homo sap...    72   3e-12
gi|148470404 heterogeneous nuclear ribonucleoprotein F [Homo sap...    72   3e-12
gi|148470402 heterogeneous nuclear ribonucleoprotein F [Homo sap...    72   3e-12
gi|148470400 heterogeneous nuclear ribonucleoprotein F [Homo sap...    72   3e-12

>gi|226497734 RNA binding motif protein 19 [Homo sapiens]
          Length = 960

 Score = 1907 bits (4940), Expect = 0.0
 Identities = 960/960 (100%), Positives = 960/960 (100%)

Query: 1   MSRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQK 60
           MSRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQK
Sbjct: 1   MSRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQK 60

Query: 61  HFNKSFIDTSRITVEFCKSFGDPAKPRAWSKHAQKPSQPKQPPKDSTTPEIKKDEKKKKV 120
           HFNKSFIDTSRITVEFCKSFGDPAKPRAWSKHAQKPSQPKQPPKDSTTPEIKKDEKKKKV
Sbjct: 61  HFNKSFIDTSRITVEFCKSFGDPAKPRAWSKHAQKPSQPKQPPKDSTTPEIKKDEKKKKV 120

Query: 121 AGQLEKLKEDTEFQEFLSVHQRRAQAATWANDGLDAEPSKGKSKPASDYLNFDSDSGQES 180
           AGQLEKLKEDTEFQEFLSVHQRRAQAATWANDGLDAEPSKGKSKPASDYLNFDSDSGQES
Sbjct: 121 AGQLEKLKEDTEFQEFLSVHQRRAQAATWANDGLDAEPSKGKSKPASDYLNFDSDSGQES 180

Query: 181 EEEGAGEDLEEEASLEPKAAVQKELSDMDYLKSKMVKAGSSSSSEEEESEDEAVHCDEGS 240
           EEEGAGEDLEEEASLEPKAAVQKELSDMDYLKSKMVKAGSSSSSEEEESEDEAVHCDEGS
Sbjct: 181 EEEGAGEDLEEEASLEPKAAVQKELSDMDYLKSKMVKAGSSSSSEEEESEDEAVHCDEGS 240

Query: 241 EAEEEDSSATPVLQERDSKGAGQEQGMPAGKKRPPEARAETEKPANQKEPTTCHTVKLRG 300
           EAEEEDSSATPVLQERDSKGAGQEQGMPAGKKRPPEARAETEKPANQKEPTTCHTVKLRG
Sbjct: 241 EAEEEDSSATPVLQERDSKGAGQEQGMPAGKKRPPEARAETEKPANQKEPTTCHTVKLRG 300

Query: 301 APFNVTEKNVMEFLAPLKPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCNREYMGGR 360
           APFNVTEKNVMEFLAPLKPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCNREYMGGR
Sbjct: 301 APFNVTEKNVMEFLAPLKPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCNREYMGGR 360

Query: 361 YIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEK 420
           YIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEK
Sbjct: 361 YIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEK 420

Query: 421 LFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHVLPSTI 480
           LFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHVLPSTI
Sbjct: 421 LFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHVLPSTI 480

Query: 481 KKEASEDASALGSSSYKKKKEAQDKANSASSHNWNTLFMGPNAVADAIAQKYNATKSQVF 540
           KKEASEDASALGSSSYKKKKEAQDKANSASSHNWNTLFMGPNAVADAIAQKYNATKSQVF
Sbjct: 481 KKEASEDASALGSSSYKKKKEAQDKANSASSHNWNTLFMGPNAVADAIAQKYNATKSQVF 540

Query: 541 DHETKGSVAVRVALGETQLVQEVRRFLIDNGVSLDSFSQAAAERSKTVILVKNLPAGTLA 600
           DHETKGSVAVRVALGETQLVQEVRRFLIDNGVSLDSFSQAAAERSKTVILVKNLPAGTLA
Sbjct: 541 DHETKGSVAVRVALGETQLVQEVRRFLIDNGVSLDSFSQAAAERSKTVILVKNLPAGTLA 600

Query: 601 AQLQETFGHFGSLGRVLLPEGGITAIVEFLEPLEARKAFRHLAYSKFHHVPLYLEWAPVG 660
           AQLQETFGHFGSLGRVLLPEGGITAIVEFLEPLEARKAFRHLAYSKFHHVPLYLEWAPVG
Sbjct: 601 AQLQETFGHFGSLGRVLLPEGGITAIVEFLEPLEARKAFRHLAYSKFHHVPLYLEWAPVG 660

Query: 661 VFSSTAPQKKKLQDTPSEPMEKDPAEPETVPDGETPEDENPTEEGADNSSAKMEEEEEEE 720
           VFSSTAPQKKKLQDTPSEPMEKDPAEPETVPDGETPEDENPTEEGADNSSAKMEEEEEEE
Sbjct: 661 VFSSTAPQKKKLQDTPSEPMEKDPAEPETVPDGETPEDENPTEEGADNSSAKMEEEEEEE 720

Query: 721 EEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVE 780
           EEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVE
Sbjct: 721 EEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVE 780

Query: 781 YRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIP 840
           YRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIP
Sbjct: 781 YRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIP 840

Query: 841 FQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNALCHSTHL 900
           FQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNALCHSTHL
Sbjct: 841 FQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNALCHSTHL 900

Query: 901 YGRRLVLEWADSEVTLQALRRKTAAHFHEPPKKKRSVVLDEILEQLEGSDSDSEEQTLQL 960
           YGRRLVLEWADSEVTLQALRRKTAAHFHEPPKKKRSVVLDEILEQLEGSDSDSEEQTLQL
Sbjct: 901 YGRRLVLEWADSEVTLQALRRKTAAHFHEPPKKKRSVVLDEILEQLEGSDSDSEEQTLQL 960


>gi|226497654 RNA binding motif protein 19 [Homo sapiens]
          Length = 960

 Score = 1907 bits (4940), Expect = 0.0
 Identities = 960/960 (100%), Positives = 960/960 (100%)

Query: 1   MSRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQK 60
           MSRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQK
Sbjct: 1   MSRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQK 60

Query: 61  HFNKSFIDTSRITVEFCKSFGDPAKPRAWSKHAQKPSQPKQPPKDSTTPEIKKDEKKKKV 120
           HFNKSFIDTSRITVEFCKSFGDPAKPRAWSKHAQKPSQPKQPPKDSTTPEIKKDEKKKKV
Sbjct: 61  HFNKSFIDTSRITVEFCKSFGDPAKPRAWSKHAQKPSQPKQPPKDSTTPEIKKDEKKKKV 120

Query: 121 AGQLEKLKEDTEFQEFLSVHQRRAQAATWANDGLDAEPSKGKSKPASDYLNFDSDSGQES 180
           AGQLEKLKEDTEFQEFLSVHQRRAQAATWANDGLDAEPSKGKSKPASDYLNFDSDSGQES
Sbjct: 121 AGQLEKLKEDTEFQEFLSVHQRRAQAATWANDGLDAEPSKGKSKPASDYLNFDSDSGQES 180

Query: 181 EEEGAGEDLEEEASLEPKAAVQKELSDMDYLKSKMVKAGSSSSSEEEESEDEAVHCDEGS 240
           EEEGAGEDLEEEASLEPKAAVQKELSDMDYLKSKMVKAGSSSSSEEEESEDEAVHCDEGS
Sbjct: 181 EEEGAGEDLEEEASLEPKAAVQKELSDMDYLKSKMVKAGSSSSSEEEESEDEAVHCDEGS 240

Query: 241 EAEEEDSSATPVLQERDSKGAGQEQGMPAGKKRPPEARAETEKPANQKEPTTCHTVKLRG 300
           EAEEEDSSATPVLQERDSKGAGQEQGMPAGKKRPPEARAETEKPANQKEPTTCHTVKLRG
Sbjct: 241 EAEEEDSSATPVLQERDSKGAGQEQGMPAGKKRPPEARAETEKPANQKEPTTCHTVKLRG 300

Query: 301 APFNVTEKNVMEFLAPLKPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCNREYMGGR 360
           APFNVTEKNVMEFLAPLKPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCNREYMGGR
Sbjct: 301 APFNVTEKNVMEFLAPLKPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCNREYMGGR 360

Query: 361 YIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEK 420
           YIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEK
Sbjct: 361 YIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEK 420

Query: 421 LFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHVLPSTI 480
           LFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHVLPSTI
Sbjct: 421 LFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHVLPSTI 480

Query: 481 KKEASEDASALGSSSYKKKKEAQDKANSASSHNWNTLFMGPNAVADAIAQKYNATKSQVF 540
           KKEASEDASALGSSSYKKKKEAQDKANSASSHNWNTLFMGPNAVADAIAQKYNATKSQVF
Sbjct: 481 KKEASEDASALGSSSYKKKKEAQDKANSASSHNWNTLFMGPNAVADAIAQKYNATKSQVF 540

Query: 541 DHETKGSVAVRVALGETQLVQEVRRFLIDNGVSLDSFSQAAAERSKTVILVKNLPAGTLA 600
           DHETKGSVAVRVALGETQLVQEVRRFLIDNGVSLDSFSQAAAERSKTVILVKNLPAGTLA
Sbjct: 541 DHETKGSVAVRVALGETQLVQEVRRFLIDNGVSLDSFSQAAAERSKTVILVKNLPAGTLA 600

Query: 601 AQLQETFGHFGSLGRVLLPEGGITAIVEFLEPLEARKAFRHLAYSKFHHVPLYLEWAPVG 660
           AQLQETFGHFGSLGRVLLPEGGITAIVEFLEPLEARKAFRHLAYSKFHHVPLYLEWAPVG
Sbjct: 601 AQLQETFGHFGSLGRVLLPEGGITAIVEFLEPLEARKAFRHLAYSKFHHVPLYLEWAPVG 660

Query: 661 VFSSTAPQKKKLQDTPSEPMEKDPAEPETVPDGETPEDENPTEEGADNSSAKMEEEEEEE 720
           VFSSTAPQKKKLQDTPSEPMEKDPAEPETVPDGETPEDENPTEEGADNSSAKMEEEEEEE
Sbjct: 661 VFSSTAPQKKKLQDTPSEPMEKDPAEPETVPDGETPEDENPTEEGADNSSAKMEEEEEEE 720

Query: 721 EEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVE 780
           EEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVE
Sbjct: 721 EEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVE 780

Query: 781 YRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIP 840
           YRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIP
Sbjct: 781 YRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIP 840

Query: 841 FQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNALCHSTHL 900
           FQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNALCHSTHL
Sbjct: 841 FQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNALCHSTHL 900

Query: 901 YGRRLVLEWADSEVTLQALRRKTAAHFHEPPKKKRSVVLDEILEQLEGSDSDSEEQTLQL 960
           YGRRLVLEWADSEVTLQALRRKTAAHFHEPPKKKRSVVLDEILEQLEGSDSDSEEQTLQL
Sbjct: 901 YGRRLVLEWADSEVTLQALRRKTAAHFHEPPKKKRSVVLDEILEQLEGSDSDSEEQTLQL 960


>gi|226497574 RNA binding motif protein 19 [Homo sapiens]
          Length = 960

 Score = 1907 bits (4940), Expect = 0.0
 Identities = 960/960 (100%), Positives = 960/960 (100%)

Query: 1   MSRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQK 60
           MSRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQK
Sbjct: 1   MSRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQK 60

Query: 61  HFNKSFIDTSRITVEFCKSFGDPAKPRAWSKHAQKPSQPKQPPKDSTTPEIKKDEKKKKV 120
           HFNKSFIDTSRITVEFCKSFGDPAKPRAWSKHAQKPSQPKQPPKDSTTPEIKKDEKKKKV
Sbjct: 61  HFNKSFIDTSRITVEFCKSFGDPAKPRAWSKHAQKPSQPKQPPKDSTTPEIKKDEKKKKV 120

Query: 121 AGQLEKLKEDTEFQEFLSVHQRRAQAATWANDGLDAEPSKGKSKPASDYLNFDSDSGQES 180
           AGQLEKLKEDTEFQEFLSVHQRRAQAATWANDGLDAEPSKGKSKPASDYLNFDSDSGQES
Sbjct: 121 AGQLEKLKEDTEFQEFLSVHQRRAQAATWANDGLDAEPSKGKSKPASDYLNFDSDSGQES 180

Query: 181 EEEGAGEDLEEEASLEPKAAVQKELSDMDYLKSKMVKAGSSSSSEEEESEDEAVHCDEGS 240
           EEEGAGEDLEEEASLEPKAAVQKELSDMDYLKSKMVKAGSSSSSEEEESEDEAVHCDEGS
Sbjct: 181 EEEGAGEDLEEEASLEPKAAVQKELSDMDYLKSKMVKAGSSSSSEEEESEDEAVHCDEGS 240

Query: 241 EAEEEDSSATPVLQERDSKGAGQEQGMPAGKKRPPEARAETEKPANQKEPTTCHTVKLRG 300
           EAEEEDSSATPVLQERDSKGAGQEQGMPAGKKRPPEARAETEKPANQKEPTTCHTVKLRG
Sbjct: 241 EAEEEDSSATPVLQERDSKGAGQEQGMPAGKKRPPEARAETEKPANQKEPTTCHTVKLRG 300

Query: 301 APFNVTEKNVMEFLAPLKPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCNREYMGGR 360
           APFNVTEKNVMEFLAPLKPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCNREYMGGR
Sbjct: 301 APFNVTEKNVMEFLAPLKPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCNREYMGGR 360

Query: 361 YIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEK 420
           YIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEK
Sbjct: 361 YIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEK 420

Query: 421 LFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHVLPSTI 480
           LFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHVLPSTI
Sbjct: 421 LFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHVLPSTI 480

Query: 481 KKEASEDASALGSSSYKKKKEAQDKANSASSHNWNTLFMGPNAVADAIAQKYNATKSQVF 540
           KKEASEDASALGSSSYKKKKEAQDKANSASSHNWNTLFMGPNAVADAIAQKYNATKSQVF
Sbjct: 481 KKEASEDASALGSSSYKKKKEAQDKANSASSHNWNTLFMGPNAVADAIAQKYNATKSQVF 540

Query: 541 DHETKGSVAVRVALGETQLVQEVRRFLIDNGVSLDSFSQAAAERSKTVILVKNLPAGTLA 600
           DHETKGSVAVRVALGETQLVQEVRRFLIDNGVSLDSFSQAAAERSKTVILVKNLPAGTLA
Sbjct: 541 DHETKGSVAVRVALGETQLVQEVRRFLIDNGVSLDSFSQAAAERSKTVILVKNLPAGTLA 600

Query: 601 AQLQETFGHFGSLGRVLLPEGGITAIVEFLEPLEARKAFRHLAYSKFHHVPLYLEWAPVG 660
           AQLQETFGHFGSLGRVLLPEGGITAIVEFLEPLEARKAFRHLAYSKFHHVPLYLEWAPVG
Sbjct: 601 AQLQETFGHFGSLGRVLLPEGGITAIVEFLEPLEARKAFRHLAYSKFHHVPLYLEWAPVG 660

Query: 661 VFSSTAPQKKKLQDTPSEPMEKDPAEPETVPDGETPEDENPTEEGADNSSAKMEEEEEEE 720
           VFSSTAPQKKKLQDTPSEPMEKDPAEPETVPDGETPEDENPTEEGADNSSAKMEEEEEEE
Sbjct: 661 VFSSTAPQKKKLQDTPSEPMEKDPAEPETVPDGETPEDENPTEEGADNSSAKMEEEEEEE 720

Query: 721 EEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVE 780
           EEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVE
Sbjct: 721 EEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVE 780

Query: 781 YRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIP 840
           YRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIP
Sbjct: 781 YRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIP 840

Query: 841 FQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNALCHSTHL 900
           FQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNALCHSTHL
Sbjct: 841 FQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNALCHSTHL 900

Query: 901 YGRRLVLEWADSEVTLQALRRKTAAHFHEPPKKKRSVVLDEILEQLEGSDSDSEEQTLQL 960
           YGRRLVLEWADSEVTLQALRRKTAAHFHEPPKKKRSVVLDEILEQLEGSDSDSEEQTLQL
Sbjct: 901 YGRRLVLEWADSEVTLQALRRKTAAHFHEPPKKKRSVVLDEILEQLEGSDSDSEEQTLQL 960


>gi|187960109 RNA binding motif protein 28 [Homo sapiens]
          Length = 759

 Score = 92.0 bits (227), Expect = 2e-18
 Identities = 64/250 (25%), Positives = 121/250 (48%), Gaps = 28/250 (11%)

Query: 727 LPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPEQ 786
           + G TLF+  L      E+L+E+FS+VG VK C +  +K   G     GFG+V +   E 
Sbjct: 1   MAGLTLFVGRLPPSARSEQLEELFSQVGPVKQCFVVTEK---GSKACRGFGYVTFSMLED 57

Query: 787 AQKALKQLQGHVVDGHKLEVRISERATKPAVTLARK---KQVPRKQTTSK---------- 833
            Q+ALK++     +G K+ V ++++  +       K    + P+K+  +K          
Sbjct: 58  VQRALKEIT--TFEGCKINVTVAKKKLRNKTKEKGKNENSECPKKEPKAKKAKVADKKAR 115

Query: 834 ILVRNIPFQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNA 893
           +++RN+ F+    +++ +F+ FG +  V +P+K    G  RGFGFV F    +A +A   
Sbjct: 116 LIIRNLSFKCSEDDLKTVFAQFGAVLEVNIPRK--PDGKMRGFGFVQFKNLLEAGKALKG 173

Query: 894 LCHSTHLYGRRLVLEWA-------DSEVTLQALRRKTAAHFHEPPKKKRSVVLDEILEQL 946
           + +   + GR + ++WA       D++        K+    H+   KK+    +++ E+ 
Sbjct: 174 M-NMKEIKGRTVAVDWAVAKDKYKDTQSVSAIGEEKSHESKHQESVKKKGREEEDMEEEE 232

Query: 947 EGSDSDSEEQ 956
              D D +++
Sbjct: 233 NDDDDDDDDE 242



 Score = 72.8 bits (177), Expect = 1e-12
 Identities = 86/353 (24%), Positives = 140/353 (39%), Gaps = 77/353 (21%)

Query: 2   SRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKH 61
           +RLI++NL     E+  + +FA FG + + ++    DGK R FGF+ FK+  EA KA K 
Sbjct: 114 ARLIIRNLSFKCSEDDLKTVFAQFGAVLEVNIPRKPDGKMRGFGFVQFKNLLEAGKALKG 173

Query: 62  FNKSFIDTSRITVEFCKSFGDPAKPRAWSKHAQKPSQPKQPPKDSTTPEIKKDEKKKKVA 121
            N   I    + V++           A +K   K +Q      +  + E K  E  KK  
Sbjct: 174 MNMKEIKGRTVAVDW-----------AVAKDKYKDTQSVSAIGEEKSHESKHQESVKKKG 222

Query: 122 GQLEKLKEDTEFQEFLSVHQRRAQAATWANDGLDAEPSKGKSKPASDYLNFDSDSGQESE 181
            + E ++E+                                          D D   + E
Sbjct: 223 REEEDMEEEEN----------------------------------------DDDDDDDDE 242

Query: 182 EEGAGEDL-EEEASLEPKAAVQKELSDMDYLKSKMVKAGSSSSSEEEESEDEAVHCDEGS 240
           E+G  +D  EEE ++E K  V K +        +   A SS  SEE+   +E+   D+G 
Sbjct: 243 EDGVFDDEDEEEENIESK--VTKPVQIQKRAVKRPAPAKSSDHSEEDSDLEESDSIDDGE 300

Query: 241 EAEEEDSSATPVLQERDSKGAGQEQGMPAGKKRPPEARAETEKPANQKEPTTCHTVKLRG 300
           E  + D+S     +E++ K         + KK+        + P++  E     TV +R 
Sbjct: 301 ELAQSDTST----EEQEDKAV-----QVSNKKK-------RKLPSDVNEG---KTVFIRN 341

Query: 301 APFNVTEKNVMEFL---APLKPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQAL 350
             F+  E+ + E L     LK V I +  +   +K G  F  F  +E  ++ L
Sbjct: 342 LSFDSEEEELGELLQQFGELKYVRIVLHPDTEHSK-GCAFAQFMTQEAAQKCL 393



 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 83/366 (22%), Positives = 150/366 (40%), Gaps = 48/366 (13%)

Query: 579 QAAAERSKTVILVKNLPAGTLAAQLQETFGHFGSLGRVLLP---EGGITAI--VEFLEPL 633
           +A     K  ++++NL        L+  F  FG++  V +P   +G +     V+F   L
Sbjct: 106 KAKVADKKARLIIRNLSFKCSEDDLKTVFAQFGAVLEVNIPRKPDGKMRGFGFVQFKNLL 165

Query: 634 EARKAFRHLAYSKFHHVPLYLEWAPVGVFSSTAPQKKKLQDTPSEPMEKDPAEPETVPDG 693
           EA KA + +   +     + ++WA           K K +DT S     +    E+    
Sbjct: 166 EAGKALKGMNMKEIKGRTVAVDWAVA---------KDKYKDTQSVSAIGEEKSHES---- 212

Query: 694 ETPEDENPTEEGADNSSAKMEEEEEEEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKV 753
                E+  ++G +    + EE ++++++++E         ++  FD  +E+ + + SKV
Sbjct: 213 --KHQESVKKKGREEEDMEEEENDDDDDDDDE---------EDGVFDDEDEEEENIESKV 261

Query: 754 GTVKSCSISKKKNKAGVLLSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKL---EVRISE 810
              K   I K+  K            E    E++          + DG +L   +    E
Sbjct: 262 --TKPVQIQKRAVKRPAPAKSSDHSEEDSDLEESDS--------IDDGEELAQSDTSTEE 311

Query: 811 RATKPA-VTLARKKQVPRKQTTSK-ILVRNIPFQAHSREIRELFSTFGELKTVRLPKKMT 868
           +  K   V+  +K+++P      K + +RN+ F +   E+ EL   FGELK VR+     
Sbjct: 312 QEDKAVQVSNKKKRKLPSDVNEGKTVFIRNLSFDSEEEELGELLQQFGELKYVRIVLH-P 370

Query: 869 GTGTHRGFGFVDFLTKQDAKRAFNALCHSTHLYGRRLVLEWADSEVTLQALRRKTAAHFH 928
            T   +G  F  F+T++ A++   A        G  L L+    +V L A+ R  AA   
Sbjct: 371 DTEHSKGCAFAQFMTQEAAQKCLLAASPENEAGG--LKLDGRQLKVDL-AVTRDEAAKLQ 427

Query: 929 EPPKKK 934
               KK
Sbjct: 428 TTKVKK 433



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 53/211 (25%), Positives = 98/211 (46%), Gaps = 18/211 (8%)

Query: 302 PFNVTEKNVMEFLAPLKPVAIRIVRNAHGNKT--GYIFVDFSNEEEVKQALKCNREYMGG 359
           P +   + + E  + + PV    V    G+K   G+ +V FS  E+V++ALK    + G 
Sbjct: 12  PPSARSEQLEELFSQVGPVKQCFVVTEKGSKACRGFGYVTFSMLEDVQRALKEITTFEGC 71

Query: 360 RYIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESG-------RLFVRNLPYT 412
           +        NV   K   +N TK        E  ++E  A+         RL +RNL + 
Sbjct: 72  KI-------NVTVAKKKLRNKTKEKGKNENSECPKKEPKAKKAKVADKKARLIIRNLSFK 124

Query: 413 STEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRM 472
            +E+DL+ +F+++G + E++ P      K +GF F+ F     A KA   ++ +  +GR 
Sbjct: 125 CSEDDLKTVFAQFGAVLEVNIP-RKPDGKMRGFGFVQFKNLLEAGKALKGMNMKEIKGRT 183

Query: 473 LHVLPSTIKKEASEDASALGSSSYKKKKEAQ 503
           + V    + K+  +D  ++ +   +K  E++
Sbjct: 184 VAV-DWAVAKDKYKDTQSVSAIGEEKSHESK 213



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 31/107 (28%), Positives = 58/107 (54%), Gaps = 4/107 (3%)

Query: 700 NPTEEGADNSSAKMEEEEEEEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSC 759
           N T+E   N +++  ++E + ++ + +     L I+NL+F  +E+ LK VF++ G V   
Sbjct: 84  NKTKEKGKNENSECPKKEPKAKKAKVADKKARLIIRNLSFKCSEDDLKTVFAQFGAVLEV 143

Query: 760 SISKKKNKAGVLLSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKLEV 806
           +I +K +        GFGFV+++   +A KALK +    + G  + V
Sbjct: 144 NIPRKPDGK----MRGFGFVQFKNLLEAGKALKGMNMKEIKGRTVAV 186



 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 30/106 (28%), Positives = 52/106 (49%), Gaps = 4/106 (3%)

Query: 404 LFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEV 463
           LFV  LP ++  E LE+LFS+ GP+ +     +  +K  +GF ++TF   E   +A  E+
Sbjct: 6   LFVGRLPPSARSEQLEELFSQVGPVKQCFVVTEKGSKACRGFGYVTFSMLEDVQRALKEI 65

Query: 464 DGQVFQGRMLHVLPSTIKKEASEDASALGSSSYKKKKEAQDKANSA 509
               F+G  ++V  +  KK+        G +   +  + + KA  A
Sbjct: 66  --TTFEGCKINV--TVAKKKLRNKTKEKGKNENSECPKKEPKAKKA 107



 Score = 47.4 bits (111), Expect = 7e-05
 Identities = 31/96 (32%), Positives = 47/96 (48%), Gaps = 6/96 (6%)

Query: 397 DLAESGRLFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHA 456
           D+ E   +F+RNL + S EE+L +L  ++G L  +   +   T+  KG AF  FM  E A
Sbjct: 330 DVNEGKTVFIRNLSFDSEEEELGELLQQFGELKYVRIVLHPDTEHSKGCAFAQFMTQEAA 389

Query: 457 VKAY------SEVDGQVFQGRMLHVLPSTIKKEASE 486
            K        +E  G    GR L V  +  + EA++
Sbjct: 390 QKCLLAASPENEAGGLKLDGRQLKVDLAVTRDEAAK 425


>gi|14110420 heterogeneous nuclear ribonucleoprotein D isoform a
           [Homo sapiens]
          Length = 355

 Score = 82.8 bits (203), Expect = 1e-15
 Identities = 60/202 (29%), Positives = 94/202 (46%), Gaps = 24/202 (11%)

Query: 699 ENPTEEGADNSSAKMEEEEEEEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKS 758
           +N  +EG  NSS +  E    + EE +      +FI  L++DTT++ LK+ FSK G V  
Sbjct: 72  KNEEDEGHSNSSPRHSEAATAQREEWK------MFIGGLSWDTTKKDLKDYFSKFGEVVD 125

Query: 759 CSISKKKNKAGVLLSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVT 818
           C++   K       S GFGFV +++ E   K + Q +      HKL  ++        + 
Sbjct: 126 CTL---KLDPITGRSRGFGFVLFKESESVDKVMDQKE------HKLNGKV--------ID 168

Query: 819 LARKKQVPRKQTTSKILVRNIPFQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGF 878
             R K +  K+   KI V  +       +IRE F  FGE++++ LP     T   RGF F
Sbjct: 169 PKRAKAMKTKEPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMD-NKTNKRRGFCF 227

Query: 879 VDFLTKQDAKRAFNALCHSTHL 900
           + F  ++  K+      H+  L
Sbjct: 228 ITFKEEEPVKKIMEKKYHNVGL 249



 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 41/205 (20%), Positives = 76/205 (37%), Gaps = 31/205 (15%)

Query: 260 GAGQEQGMPAGKKRPPEARAETEKPANQKEPTTCHTVKLR----GAPFNVTEKNVMEFLA 315
           G+ + +G      +  E    +       E  T    + +    G  ++ T+K++ ++ +
Sbjct: 59  GSAESEGAKIDASKNEEDEGHSNSSPRHSEAATAQREEWKMFIGGLSWDTTKKDLKDYFS 118

Query: 316 PLKPVAIRIVR--NAHGNKTGYIFVDFSNEEEVKQALKCNREYMGGRYIEVFREKNVPTT 373
               V    ++     G   G+ FV F   E V + +      + G+ I+  R K + T 
Sbjct: 119 KFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMKTK 178

Query: 374 KGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEKLFSKYGPLSELHY 433
           +   K                         +FV  L   + EE + + F  +G +  +  
Sbjct: 179 EPVKK-------------------------IFVGGLSPDTPEEKIREYFGGFGEVESIEL 213

Query: 434 PIDSLTKKPKGFAFITFMFPEHAVK 458
           P+D+ T K +GF FITF   E   K
Sbjct: 214 PMDNKTNKRRGFCFITFKEEEPVKK 238



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 18/63 (28%), Positives = 35/63 (55%)

Query: 400 ESGRLFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKA 459
           E  ++F+  L + +T++DL+  FSK+G + +    +D +T + +GF F+ F   E   K 
Sbjct: 95  EEWKMFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKV 154

Query: 460 YSE 462
             +
Sbjct: 155 MDQ 157



 Score = 35.0 bits (79), Expect = 0.34
 Identities = 21/74 (28%), Positives = 33/74 (44%), Gaps = 5/74 (6%)

Query: 3   RLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTK-DGKFRKFGFIGFKSEEEAQKA--- 58
           ++ +  L     ++  +  F+ FG + DC+LK     G+ R FGF+ FK  E   K    
Sbjct: 98  KMFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQ 157

Query: 59  -QKHFNKSFIDTSR 71
            +   N   ID  R
Sbjct: 158 KEHKLNGKVIDPKR 171



 Score = 34.7 bits (78), Expect = 0.44
 Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 2/80 (2%)

Query: 1   MSRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKF-TKDGKFRKFGFIGFKSEEEAQK-A 58
           + ++ V  L     EE+ R+ F  FG +    L    K  K R F FI FK EE  +K  
Sbjct: 181 VKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIM 240

Query: 59  QKHFNKSFIDTSRITVEFCK 78
           +K ++   +    I V   K
Sbjct: 241 EKKYHNVGLSKCEIKVAMSK 260


>gi|14110414 heterogeneous nuclear ribonucleoprotein D isoform c
           [Homo sapiens]
          Length = 306

 Score = 82.8 bits (203), Expect = 1e-15
 Identities = 60/202 (29%), Positives = 94/202 (46%), Gaps = 24/202 (11%)

Query: 699 ENPTEEGADNSSAKMEEEEEEEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKS 758
           +N  +EG  NSS +  E    + EE +      +FI  L++DTT++ LK+ FSK G V  
Sbjct: 72  KNEEDEGHSNSSPRHSEAATAQREEWK------MFIGGLSWDTTKKDLKDYFSKFGEVVD 125

Query: 759 CSISKKKNKAGVLLSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVT 818
           C++   K       S GFGFV +++ E   K + Q +      HKL  ++        + 
Sbjct: 126 CTL---KLDPITGRSRGFGFVLFKESESVDKVMDQKE------HKLNGKV--------ID 168

Query: 819 LARKKQVPRKQTTSKILVRNIPFQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGF 878
             R K +  K+   KI V  +       +IRE F  FGE++++ LP     T   RGF F
Sbjct: 169 PKRAKAMKTKEPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMD-NKTNKRRGFCF 227

Query: 879 VDFLTKQDAKRAFNALCHSTHL 900
           + F  ++  K+      H+  L
Sbjct: 228 ITFKEEEPVKKIMEKKYHNVGL 249



 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 41/205 (20%), Positives = 76/205 (37%), Gaps = 31/205 (15%)

Query: 260 GAGQEQGMPAGKKRPPEARAETEKPANQKEPTTCHTVKLR----GAPFNVTEKNVMEFLA 315
           G+ + +G      +  E    +       E  T    + +    G  ++ T+K++ ++ +
Sbjct: 59  GSAESEGAKIDASKNEEDEGHSNSSPRHSEAATAQREEWKMFIGGLSWDTTKKDLKDYFS 118

Query: 316 PLKPVAIRIVR--NAHGNKTGYIFVDFSNEEEVKQALKCNREYMGGRYIEVFREKNVPTT 373
               V    ++     G   G+ FV F   E V + +      + G+ I+  R K + T 
Sbjct: 119 KFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMKTK 178

Query: 374 KGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEKLFSKYGPLSELHY 433
           +   K                         +FV  L   + EE + + F  +G +  +  
Sbjct: 179 EPVKK-------------------------IFVGGLSPDTPEEKIREYFGGFGEVESIEL 213

Query: 434 PIDSLTKKPKGFAFITFMFPEHAVK 458
           P+D+ T K +GF FITF   E   K
Sbjct: 214 PMDNKTNKRRGFCFITFKEEEPVKK 238



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 18/63 (28%), Positives = 35/63 (55%)

Query: 400 ESGRLFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKA 459
           E  ++F+  L + +T++DL+  FSK+G + +    +D +T + +GF F+ F   E   K 
Sbjct: 95  EEWKMFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKV 154

Query: 460 YSE 462
             +
Sbjct: 155 MDQ 157



 Score = 35.0 bits (79), Expect = 0.34
 Identities = 21/74 (28%), Positives = 33/74 (44%), Gaps = 5/74 (6%)

Query: 3   RLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTK-DGKFRKFGFIGFKSEEEAQKA--- 58
           ++ +  L     ++  +  F+ FG + DC+LK     G+ R FGF+ FK  E   K    
Sbjct: 98  KMFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQ 157

Query: 59  -QKHFNKSFIDTSR 71
            +   N   ID  R
Sbjct: 158 KEHKLNGKVIDPKR 171



 Score = 34.7 bits (78), Expect = 0.44
 Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 2/80 (2%)

Query: 1   MSRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKF-TKDGKFRKFGFIGFKSEEEAQK-A 58
           + ++ V  L     EE+ R+ F  FG +    L    K  K R F FI FK EE  +K  
Sbjct: 181 VKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIM 240

Query: 59  QKHFNKSFIDTSRITVEFCK 78
           +K ++   +    I V   K
Sbjct: 241 EKKYHNVGLSKCEIKVAMSK 260


>gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens]
          Length = 382

 Score = 82.0 bits (201), Expect = 2e-15
 Identities = 55/188 (29%), Positives = 92/188 (48%), Gaps = 12/188 (6%)

Query: 712 KMEEEEEEEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVL 771
           K  EE   E    +      +F+KN+  D  +EKLKE+F + G  +S  + +  +     
Sbjct: 181 KFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGK--- 237

Query: 772 LSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTT 831
            S GFGFV Y   E AQKA+  L G  +DG  L V  +++  +    L R+ +  R +  
Sbjct: 238 -SKGFGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEK 296

Query: 832 SK-----ILVRNIPFQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQD 886
           S+     I ++N+    +  +++E FS+FG +      K M   G  +GFG V F + ++
Sbjct: 297 SRPPGVPIYIKNLDETINDEKLKEEFSSFGSISRA---KVMMEVGQGKGFGVVCFSSFEE 353

Query: 887 AKRAFNAL 894
           A +A + +
Sbjct: 354 ATKAVDEM 361



 Score = 53.9 bits (128), Expect = 7e-07
 Identities = 50/213 (23%), Positives = 97/213 (45%), Gaps = 24/213 (11%)

Query: 270 GKKRPPEARAETEKPANQKEPTTCHTVKLRGAPFNVTEKNVMEFLAPLKPV-AIRIVRNA 328
           G+ + PE RA   +    ++  T   V ++    ++ ++ + E      P  +++++R+A
Sbjct: 178 GRFKFPEERAAEVRT---RDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDA 234

Query: 329 HGNKTGYIFVDFSNEEEVKQA-LKCNREYMGGRYIEVFREKNVPTTKGAPKNTTKSWQGR 387
            G   G+ FV +   E  ++A L  + + + G+ + V R         A K   +  +  
Sbjct: 235 SGKSKGFGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGR---------AQKKIERLAE-- 283

Query: 388 ILGENEEEEDLAESGR-----LFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKP 442
            L    E   L E  R     ++++NL  T  +E L++ FS +G +S     ++    + 
Sbjct: 284 -LRRRFERLRLKEKSRPPGVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMME--VGQG 340

Query: 443 KGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHV 475
           KGF  + F   E A KA  E++G++   + LHV
Sbjct: 341 KGFGVVCFSSFEEATKAVDEMNGRIVGSKPLHV 373



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 32/89 (35%), Positives = 47/89 (52%), Gaps = 5/89 (5%)

Query: 722 EEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEY 781
           +E+   PG  ++IKNL+    +EKLKE FS  G     SIS+ K    V    GFG V +
Sbjct: 294 KEKSRPPGVPIYIKNLDETINDEKLKEEFSSFG-----SISRAKVMMEVGQGKGFGVVCF 348

Query: 782 RKPEQAQKALKQLQGHVVDGHKLEVRISE 810
              E+A KA+ ++ G +V    L V + +
Sbjct: 349 SSFEEATKAVDEMNGRIVGSKPLHVTLGQ 377



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 41/174 (23%), Positives = 76/174 (43%), Gaps = 23/174 (13%)

Query: 732 LFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPEQAQKAL 791
           L++ +L+ D TE+ L + F   G ++   I +       L   G+G+V +R P  A+ AL
Sbjct: 20  LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPL---GYGYVNFRFPADAEWAL 76

Query: 792 KQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIPFQAHSREIREL 851
             +   +++G    +  S+   +            RK     I ++N+     +R +  L
Sbjct: 77  NTMNFDLINGKPFRLMWSQPDDR-----------LRKSGVGNIFIKNLDKSIDNRALFYL 125

Query: 852 FSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNALCHSTHLYGRRL 905
           FS FG + + ++     G+   +G+ +V F +   A RA        H+ G RL
Sbjct: 126 FSAFGNILSCKVVCDDNGS---KGYAYVHFDSLAAANRAI------WHMNGVRL 170



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 19/67 (28%), Positives = 36/67 (53%)

Query: 2   SRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKH 61
           + + VKN+ + + +E+ ++LF  +G      +     GK + FGF+ +++ E AQKA   
Sbjct: 199 TNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFGFVRYETHEAAQKAVLD 258

Query: 62  FNKSFID 68
            +   ID
Sbjct: 259 LHGKSID 265



 Score = 38.5 bits (88), Expect = 0.030
 Identities = 21/73 (28%), Positives = 36/73 (49%)

Query: 404 LFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEV 463
           L+V +L    TE+ L K F   GPL       D +T+ P G+ ++ F FP  A  A + +
Sbjct: 20  LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTM 79

Query: 464 DGQVFQGRMLHVL 476
           +  +  G+   ++
Sbjct: 80  NFDLINGKPFRLM 92



 Score = 37.0 bits (84), Expect = 0.089
 Identities = 19/71 (26%), Positives = 39/71 (54%), Gaps = 1/71 (1%)

Query: 4   LIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKHFN 63
           + +KNL   + +E+ ++ F++FG+++   +   + G+ + FG + F S EEA KA    N
Sbjct: 304 IYIKNLDETINDEKLKEEFSSFGSISRAKV-MMEVGQGKGFGVVCFSSFEEATKAVDEMN 362

Query: 64  KSFIDTSRITV 74
              + +  + V
Sbjct: 363 GRIVGSKPLHV 373



 Score = 32.3 bits (72), Expect = 2.2
 Identities = 17/74 (22%), Positives = 34/74 (45%), Gaps = 1/74 (1%)

Query: 1   MSRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQK 60
           +  + +KNL   +       LF+AFG +  C +    +G  + + ++ F S   A +A  
Sbjct: 105 VGNIFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDDNGS-KGYAYVHFDSLAAANRAIW 163

Query: 61  HFNKSFIDTSRITV 74
           H N   ++  ++ V
Sbjct: 164 HMNGVRLNNRQVYV 177


>gi|14110417 heterogeneous nuclear ribonucleoprotein D isoform b
           [Homo sapiens]
          Length = 336

 Score = 81.3 bits (199), Expect = 4e-15
 Identities = 60/200 (30%), Positives = 96/200 (48%), Gaps = 26/200 (13%)

Query: 702 TEEG-ADNSSAKMEEEEEEEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCS 760
           TE G A++  AK++  + EE+E +       +FI  L++DTT++ LK+ FSK G V  C+
Sbjct: 56  TEGGSAESEGAKIDASKNEEDEGK-------MFIGGLSWDTTKKDLKDYFSKFGEVVDCT 108

Query: 761 ISKKKNKAGVLLSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVTLA 820
           +   K       S GFGFV +++ E   K + Q +      HKL  ++        +   
Sbjct: 109 L---KLDPITGRSRGFGFVLFKESESVDKVMDQKE------HKLNGKV--------IDPK 151

Query: 821 RKKQVPRKQTTSKILVRNIPFQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVD 880
           R K +  K+   KI V  +       +IRE F  FGE++++ LP     T   RGF F+ 
Sbjct: 152 RAKAMKTKEPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMD-NKTNKRRGFCFIT 210

Query: 881 FLTKQDAKRAFNALCHSTHL 900
           F  ++  K+      H+  L
Sbjct: 211 FKEEEPVKKIMEKKYHNVGL 230



 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 51/224 (22%), Positives = 86/224 (38%), Gaps = 29/224 (12%)

Query: 239 GSEAEEEDS--SATPVLQERDSKGAGQEQGMPAGKKRPPEARAETEKPANQKEPTTCHTV 296
           GS  E+E +  +AT         GAG   G  +G      A +E  K    K       +
Sbjct: 21  GSAGEQEGAMVAATQGAAAAAGSGAGTGGGTASGGTEGGSAESEGAKIDASKNEEDEGKM 80

Query: 297 KLRGAPFNVTEKNVMEFLAPLKPVAIRIVR--NAHGNKTGYIFVDFSNEEEVKQALKCNR 354
            + G  ++ T+K++ ++ +    V    ++     G   G+ FV F   E V + +    
Sbjct: 81  FIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKE 140

Query: 355 EYMGGRYIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTST 414
             + G+ I+  R K + T +   K                         +FV  L   + 
Sbjct: 141 HKLNGKVIDPKRAKAMKTKEPVKK-------------------------IFVGGLSPDTP 175

Query: 415 EEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVK 458
           EE + + F  +G +  +  P+D+ T K +GF FITF   E   K
Sbjct: 176 EEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKK 219



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 24/91 (26%), Positives = 47/91 (51%), Gaps = 3/91 (3%)

Query: 372 TTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEKLFSKYGPLSEL 431
           T  G  +  +   +G  +  ++ EED    G++F+  L + +T++DL+  FSK+G + + 
Sbjct: 51  TASGGTEGGSAESEGAKIDASKNEED---EGKMFIGGLSWDTTKKDLKDYFSKFGEVVDC 107

Query: 432 HYPIDSLTKKPKGFAFITFMFPEHAVKAYSE 462
              +D +T + +GF F+ F   E   K   +
Sbjct: 108 TLKLDPITGRSRGFGFVLFKESESVDKVMDQ 138



 Score = 35.0 bits (79), Expect = 0.34
 Identities = 21/74 (28%), Positives = 33/74 (44%), Gaps = 5/74 (6%)

Query: 3   RLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTK-DGKFRKFGFIGFKSEEEAQKA--- 58
           ++ +  L     ++  +  F+ FG + DC+LK     G+ R FGF+ FK  E   K    
Sbjct: 79  KMFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQ 138

Query: 59  -QKHFNKSFIDTSR 71
            +   N   ID  R
Sbjct: 139 KEHKLNGKVIDPKR 152



 Score = 34.7 bits (78), Expect = 0.44
 Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 2/80 (2%)

Query: 1   MSRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKF-TKDGKFRKFGFIGFKSEEEAQK-A 58
           + ++ V  L     EE+ R+ F  FG +    L    K  K R F FI FK EE  +K  
Sbjct: 162 VKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIM 221

Query: 59  QKHFNKSFIDTSRITVEFCK 78
           +K ++   +    I V   K
Sbjct: 222 EKKYHNVGLSKCEIKVAMSK 241


>gi|51477708 heterogeneous nuclear ribonucleoprotein D isoform d
           [Homo sapiens]
          Length = 287

 Score = 81.3 bits (199), Expect = 4e-15
 Identities = 60/200 (30%), Positives = 96/200 (48%), Gaps = 26/200 (13%)

Query: 702 TEEG-ADNSSAKMEEEEEEEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCS 760
           TE G A++  AK++  + EE+E +       +FI  L++DTT++ LK+ FSK G V  C+
Sbjct: 56  TEGGSAESEGAKIDASKNEEDEGK-------MFIGGLSWDTTKKDLKDYFSKFGEVVDCT 108

Query: 761 ISKKKNKAGVLLSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVTLA 820
           +   K       S GFGFV +++ E   K + Q +      HKL  ++        +   
Sbjct: 109 L---KLDPITGRSRGFGFVLFKESESVDKVMDQKE------HKLNGKV--------IDPK 151

Query: 821 RKKQVPRKQTTSKILVRNIPFQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVD 880
           R K +  K+   KI V  +       +IRE F  FGE++++ LP     T   RGF F+ 
Sbjct: 152 RAKAMKTKEPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMD-NKTNKRRGFCFIT 210

Query: 881 FLTKQDAKRAFNALCHSTHL 900
           F  ++  K+      H+  L
Sbjct: 211 FKEEEPVKKIMEKKYHNVGL 230



 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 51/224 (22%), Positives = 86/224 (38%), Gaps = 29/224 (12%)

Query: 239 GSEAEEEDS--SATPVLQERDSKGAGQEQGMPAGKKRPPEARAETEKPANQKEPTTCHTV 296
           GS  E+E +  +AT         GAG   G  +G      A +E  K    K       +
Sbjct: 21  GSAGEQEGAMVAATQGAAAAAGSGAGTGGGTASGGTEGGSAESEGAKIDASKNEEDEGKM 80

Query: 297 KLRGAPFNVTEKNVMEFLAPLKPVAIRIVR--NAHGNKTGYIFVDFSNEEEVKQALKCNR 354
            + G  ++ T+K++ ++ +    V    ++     G   G+ FV F   E V + +    
Sbjct: 81  FIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKE 140

Query: 355 EYMGGRYIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTST 414
             + G+ I+  R K + T +   K                         +FV  L   + 
Sbjct: 141 HKLNGKVIDPKRAKAMKTKEPVKK-------------------------IFVGGLSPDTP 175

Query: 415 EEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVK 458
           EE + + F  +G +  +  P+D+ T K +GF FITF   E   K
Sbjct: 176 EEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKK 219



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 24/91 (26%), Positives = 47/91 (51%), Gaps = 3/91 (3%)

Query: 372 TTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEKLFSKYGPLSEL 431
           T  G  +  +   +G  +  ++ EED    G++F+  L + +T++DL+  FSK+G + + 
Sbjct: 51  TASGGTEGGSAESEGAKIDASKNEED---EGKMFIGGLSWDTTKKDLKDYFSKFGEVVDC 107

Query: 432 HYPIDSLTKKPKGFAFITFMFPEHAVKAYSE 462
              +D +T + +GF F+ F   E   K   +
Sbjct: 108 TLKLDPITGRSRGFGFVLFKESESVDKVMDQ 138



 Score = 35.0 bits (79), Expect = 0.34
 Identities = 21/74 (28%), Positives = 33/74 (44%), Gaps = 5/74 (6%)

Query: 3   RLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTK-DGKFRKFGFIGFKSEEEAQKA--- 58
           ++ +  L     ++  +  F+ FG + DC+LK     G+ R FGF+ FK  E   K    
Sbjct: 79  KMFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQ 138

Query: 59  -QKHFNKSFIDTSR 71
            +   N   ID  R
Sbjct: 139 KEHKLNGKVIDPKR 152



 Score = 34.7 bits (78), Expect = 0.44
 Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 2/80 (2%)

Query: 1   MSRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKF-TKDGKFRKFGFIGFKSEEEAQK-A 58
           + ++ V  L     EE+ R+ F  FG +    L    K  K R F FI FK EE  +K  
Sbjct: 162 VKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIM 221

Query: 59  QKHFNKSFIDTSRITVEFCK 78
           +K ++   +    I V   K
Sbjct: 222 EKKYHNVGLSKCEIKVAMSK 241


>gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Homo
           sapiens]
          Length = 631

 Score = 80.9 bits (198), Expect = 5e-15
 Identities = 57/210 (27%), Positives = 99/210 (47%), Gaps = 28/210 (13%)

Query: 702 TEEGADNSSAKME----------------EEEEEEEEEEESLPGCTLFIKNLNFDTTEEK 745
           T+E AD +  KM                  +E E E   ++     ++IKN   +  +E 
Sbjct: 147 TQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDES 206

Query: 746 LKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKLE 805
           LKE+FS+ G   S  + +  N      S GFGFV Y K E A KA++++ G  + G  + 
Sbjct: 207 LKELFSQFGKTLSVKVMRDPNGK----SKGFGFVSYEKHEDANKAVEEMNGKEISGKIIF 262

Query: 806 VRISERATKPAVTLARKKQVPRKQTTSK-----ILVRNIPFQAHSREIRELFSTFGELKT 860
           V  +++  +    L RK +  +++  S+     + ++N+       ++R+ FS FG + +
Sbjct: 263 VGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITS 322

Query: 861 VRLPKKMTGTGTHRGFGFVDFLTKQDAKRA 890
               K M   G  +GFGFV F + ++A +A
Sbjct: 323 A---KVMLEDGRSKGFGFVCFSSPEEATKA 349



 Score = 77.8 bits (190), Expect = 5e-14
 Identities = 85/410 (20%), Positives = 162/410 (39%), Gaps = 54/410 (13%)

Query: 404 LFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEV 463
           L+V +L    TE  L + FS  GP+  +    D +T++  G+A++ F  P  A +A   +
Sbjct: 13  LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72

Query: 464 DGQVFQGRMLHVLPSTIKKEASEDASALGSSSYKKKKEAQDKANSASSHNWNTLFMGPNA 523
           +  V +G+ + ++ S  +++ S   S +G+   K   ++ D  N A    ++T     N 
Sbjct: 73  NFDVIKGKPIRIMWS--QRDPSLRKSGVGNVFIKNLDKSID--NKAL---YDTFSAFGNI 125

Query: 524 VADAIAQKYNATKSQVFDHETKGSVAVRVALGETQLVQEVRRFLIDNGVSLDSFSQAAAE 583
           ++  +    N +K   F H      A +       ++   R+  +    S          
Sbjct: 126 LSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGA 185

Query: 584 RSK--TVILVKNLPAGTLAAQLQETFGHFGSLGRVLLPEGGITAIVEFLEPLEARKAFRH 641
           ++K  T + +KN         L+E F  FG             ++    +P    K F  
Sbjct: 186 KAKEFTNVYIKNFGEEVDDESLKELFSQFGKT----------LSVKVMRDPNGKSKGFGF 235

Query: 642 LAYSKFHHVPLYLEWAPVGVFSSTAPQKKKLQDTPSEPMEKDPAEPETVPDGETPEDENP 701
           ++Y K                           +   E M       + +  G        
Sbjct: 236 VSYEKHEDA-----------------------NKAVEEMNGKEISGKIIFVGRA------ 266

Query: 702 TEEGADNSSAKMEEEEEEEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSI 761
            ++  +  +    + E+ ++E      G  L+IKNL+    +EKL++ FS  G++ S  +
Sbjct: 267 -QKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKV 325

Query: 762 SKKKNKAGVLLSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKLEVRISER 811
             +  +     S GFGFV +  PE+A KA+ ++ G +V    L V +++R
Sbjct: 326 MLEDGR-----SKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQR 370



 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 52/208 (25%), Positives = 104/208 (50%), Gaps = 18/208 (8%)

Query: 280 ETEKPANQKEPTTCHTVKLRGAPFNVTEKNVMEFLAPL-KPVAIRIVRNAHGNKTGYIFV 338
           E E  A  KE T    V ++     V ++++ E  +   K ++++++R+ +G   G+ FV
Sbjct: 180 EAELGAKAKEFTN---VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFV 236

Query: 339 DFSNEEEVKQALK-CNREYMGGRYIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEED 397
            +   E+  +A++  N + + G+ I V R         A K   +  + +   E  ++E 
Sbjct: 237 SYEKHEDANKAVEEMNGKEISGKIIFVGR---------AQKKVERQAELKRKFEQLKQER 287

Query: 398 LA--ESGRLFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEH 455
           ++  +   L+++NL  T  +E L K FS +G ++     ++    + KGF F+ F  PE 
Sbjct: 288 ISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEE 345

Query: 456 AVKAYSEVDGQVFQGRMLHVLPSTIKKE 483
           A KA +E++G++   + L+V  +  K+E
Sbjct: 346 ATKAVTEMNGRIVGSKPLYVALAQRKEE 373



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 41/169 (24%), Positives = 82/169 (48%), Gaps = 17/169 (10%)

Query: 726 SLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPE 785
           S P  +L++ +L+ D TE  L E FS  G V S  + +         S+G+ +V +++P 
Sbjct: 7   SYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRR---SLGYAYVNFQQPA 63

Query: 786 QAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIPFQAHS 845
            A++AL  +   V+ G  + +  S+R   P++         RK     + ++N+     +
Sbjct: 64  DAERALDTMNFDVIKGKPIRIMWSQR--DPSL---------RKSGVGNVFIKNLDKSIDN 112

Query: 846 REIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNAL 894
           + + + FS FG + + ++     G+   +G+ FV F T++ A +A   +
Sbjct: 113 KALYDTFSAFGNILSCKVVCDENGS---KGYAFVHFETQEAADKAIEKM 158



 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 24/71 (33%), Positives = 41/71 (57%), Gaps = 1/71 (1%)

Query: 4   LIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKHFN 63
           L +KNL + + +E+ R+ F+ FG++T   +   +DG+ + FGF+ F S EEA KA    N
Sbjct: 296 LYIKNLDDTIDDEKLRKEFSPFGSITSAKVML-EDGRSKGFGFVCFSSPEEATKAVTEMN 354

Query: 64  KSFIDTSRITV 74
              + +  + V
Sbjct: 355 GRIVGSKPLYV 365



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 17/62 (27%), Positives = 33/62 (53%)

Query: 2   SRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKH 61
           + + +KN    + +E  ++LF+ FG      +    +GK + FGF+ ++  E+A KA + 
Sbjct: 191 TNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEE 250

Query: 62  FN 63
            N
Sbjct: 251 MN 252



 Score = 38.5 bits (88), Expect = 0.030
 Identities = 19/79 (24%), Positives = 40/79 (50%), Gaps = 1/79 (1%)

Query: 1   MSRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQK 60
           +  + +KNL   +  +     F+AFG +  C +   ++G  + + F+ F+++E A KA +
Sbjct: 98  VGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGS-KGYAFVHFETQEAADKAIE 156

Query: 61  HFNKSFIDTSRITVEFCKS 79
             N   ++  ++ V   KS
Sbjct: 157 KMNGMLLNDRKVFVGRFKS 175


>gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo
           sapiens]
          Length = 644

 Score = 80.9 bits (198), Expect = 5e-15
 Identities = 57/210 (27%), Positives = 99/210 (47%), Gaps = 28/210 (13%)

Query: 702 TEEGADNSSAKME----------------EEEEEEEEEEESLPGCTLFIKNLNFDTTEEK 745
           T+E AD +  KM                  +E E E   ++     ++IKN   +  +E 
Sbjct: 147 TQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDES 206

Query: 746 LKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKLE 805
           LKE+FS+ G   S  + +  N      S GFGFV Y K E A KA++++ G  + G  + 
Sbjct: 207 LKELFSQFGKTLSVKVMRDPNGK----SKGFGFVSYEKHEDANKAVEEMNGKEISGKIIF 262

Query: 806 VRISERATKPAVTLARKKQVPRKQTTSK-----ILVRNIPFQAHSREIRELFSTFGELKT 860
           V  +++  +    L RK +  +++  S+     + ++N+       ++R+ FS FG + +
Sbjct: 263 VGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITS 322

Query: 861 VRLPKKMTGTGTHRGFGFVDFLTKQDAKRA 890
               K M   G  +GFGFV F + ++A +A
Sbjct: 323 A---KVMLEDGRSKGFGFVCFSSPEEATKA 349



 Score = 77.8 bits (190), Expect = 5e-14
 Identities = 85/410 (20%), Positives = 162/410 (39%), Gaps = 54/410 (13%)

Query: 404 LFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEV 463
           L+V +L    TE  L + FS  GP+  +    D +T++  G+A++ F  P  A +A   +
Sbjct: 13  LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72

Query: 464 DGQVFQGRMLHVLPSTIKKEASEDASALGSSSYKKKKEAQDKANSASSHNWNTLFMGPNA 523
           +  V +G+ + ++ S  +++ S   S +G+   K   ++ D  N A    ++T     N 
Sbjct: 73  NFDVIKGKPIRIMWS--QRDPSLRKSGVGNVFIKNLDKSID--NKAL---YDTFSAFGNI 125

Query: 524 VADAIAQKYNATKSQVFDHETKGSVAVRVALGETQLVQEVRRFLIDNGVSLDSFSQAAAE 583
           ++  +    N +K   F H      A +       ++   R+  +    S          
Sbjct: 126 LSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGA 185

Query: 584 RSK--TVILVKNLPAGTLAAQLQETFGHFGSLGRVLLPEGGITAIVEFLEPLEARKAFRH 641
           ++K  T + +KN         L+E F  FG             ++    +P    K F  
Sbjct: 186 KAKEFTNVYIKNFGEEVDDESLKELFSQFGKT----------LSVKVMRDPNGKSKGFGF 235

Query: 642 LAYSKFHHVPLYLEWAPVGVFSSTAPQKKKLQDTPSEPMEKDPAEPETVPDGETPEDENP 701
           ++Y K                           +   E M       + +  G        
Sbjct: 236 VSYEKHEDA-----------------------NKAVEEMNGKEISGKIIFVGRA------ 266

Query: 702 TEEGADNSSAKMEEEEEEEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSI 761
            ++  +  +    + E+ ++E      G  L+IKNL+    +EKL++ FS  G++ S  +
Sbjct: 267 -QKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKV 325

Query: 762 SKKKNKAGVLLSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKLEVRISER 811
             +  +     S GFGFV +  PE+A KA+ ++ G +V    L V +++R
Sbjct: 326 MLEDGR-----SKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQR 370



 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 52/208 (25%), Positives = 104/208 (50%), Gaps = 18/208 (8%)

Query: 280 ETEKPANQKEPTTCHTVKLRGAPFNVTEKNVMEFLAPL-KPVAIRIVRNAHGNKTGYIFV 338
           E E  A  KE T    V ++     V ++++ E  +   K ++++++R+ +G   G+ FV
Sbjct: 180 EAELGAKAKEFTN---VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFV 236

Query: 339 DFSNEEEVKQALK-CNREYMGGRYIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEED 397
            +   E+  +A++  N + + G+ I V R         A K   +  + +   E  ++E 
Sbjct: 237 SYEKHEDANKAVEEMNGKEISGKIIFVGR---------AQKKVERQAELKRKFEQLKQER 287

Query: 398 LA--ESGRLFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEH 455
           ++  +   L+++NL  T  +E L K FS +G ++     ++    + KGF F+ F  PE 
Sbjct: 288 ISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEE 345

Query: 456 AVKAYSEVDGQVFQGRMLHVLPSTIKKE 483
           A KA +E++G++   + L+V  +  K+E
Sbjct: 346 ATKAVTEMNGRIVGSKPLYVALAQRKEE 373



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 41/169 (24%), Positives = 82/169 (48%), Gaps = 17/169 (10%)

Query: 726 SLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPE 785
           S P  +L++ +L+ D TE  L E FS  G V S  + +         S+G+ +V +++P 
Sbjct: 7   SYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRR---SLGYAYVNFQQPA 63

Query: 786 QAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIPFQAHS 845
            A++AL  +   V+ G  + +  S+R   P++         RK     + ++N+     +
Sbjct: 64  DAERALDTMNFDVIKGKPIRIMWSQR--DPSL---------RKSGVGNVFIKNLDKSIDN 112

Query: 846 REIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNAL 894
           + + + FS FG + + ++     G+   +G+ FV F T++ A +A   +
Sbjct: 113 KALYDTFSAFGNILSCKVVCDENGS---KGYAFVHFETQEAADKAIEKM 158



 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 24/71 (33%), Positives = 41/71 (57%), Gaps = 1/71 (1%)

Query: 4   LIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKHFN 63
           L +KNL + + +E+ R+ F+ FG++T   +   +DG+ + FGF+ F S EEA KA    N
Sbjct: 296 LYIKNLDDTIDDEKLRKEFSPFGSITSAKVML-EDGRSKGFGFVCFSSPEEATKAVTEMN 354

Query: 64  KSFIDTSRITV 74
              + +  + V
Sbjct: 355 GRIVGSKPLYV 365



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 17/62 (27%), Positives = 33/62 (53%)

Query: 2   SRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKH 61
           + + +KN    + +E  ++LF+ FG      +    +GK + FGF+ ++  E+A KA + 
Sbjct: 191 TNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEE 250

Query: 62  FN 63
            N
Sbjct: 251 MN 252



 Score = 38.5 bits (88), Expect = 0.030
 Identities = 19/79 (24%), Positives = 40/79 (50%), Gaps = 1/79 (1%)

Query: 1   MSRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQK 60
           +  + +KNL   +  +     F+AFG +  C +   ++G  + + F+ F+++E A KA +
Sbjct: 98  VGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGS-KGYAFVHFETQEAADKAIE 156

Query: 61  HFNKSFIDTSRITVEFCKS 79
             N   ++  ++ V   KS
Sbjct: 157 KMNGMLLNDRKVFVGRFKS 175


>gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Homo
           sapiens]
          Length = 660

 Score = 80.9 bits (198), Expect = 5e-15
 Identities = 57/210 (27%), Positives = 99/210 (47%), Gaps = 28/210 (13%)

Query: 702 TEEGADNSSAKME----------------EEEEEEEEEEESLPGCTLFIKNLNFDTTEEK 745
           T+E AD +  KM                  +E E E   ++     ++IKN   +  +E 
Sbjct: 147 TQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDES 206

Query: 746 LKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKLE 805
           LKE+FS+ G   S  + +  N      S GFGFV Y K E A KA++++ G  + G  + 
Sbjct: 207 LKELFSQFGKTLSVKVMRDPNGK----SKGFGFVSYEKHEDANKAVEEMNGKEISGKIIF 262

Query: 806 VRISERATKPAVTLARKKQVPRKQTTSK-----ILVRNIPFQAHSREIRELFSTFGELKT 860
           V  +++  +    L RK +  +++  S+     + ++N+       ++R+ FS FG + +
Sbjct: 263 VGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITS 322

Query: 861 VRLPKKMTGTGTHRGFGFVDFLTKQDAKRA 890
               K M   G  +GFGFV F + ++A +A
Sbjct: 323 A---KVMLEDGRSKGFGFVCFSSPEEATKA 349



 Score = 77.8 bits (190), Expect = 5e-14
 Identities = 85/410 (20%), Positives = 162/410 (39%), Gaps = 54/410 (13%)

Query: 404 LFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEV 463
           L+V +L    TE  L + FS  GP+  +    D +T++  G+A++ F  P  A +A   +
Sbjct: 13  LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72

Query: 464 DGQVFQGRMLHVLPSTIKKEASEDASALGSSSYKKKKEAQDKANSASSHNWNTLFMGPNA 523
           +  V +G+ + ++ S  +++ S   S +G+   K   ++ D  N A    ++T     N 
Sbjct: 73  NFDVIKGKPIRIMWS--QRDPSLRKSGVGNVFIKNLDKSID--NKAL---YDTFSAFGNI 125

Query: 524 VADAIAQKYNATKSQVFDHETKGSVAVRVALGETQLVQEVRRFLIDNGVSLDSFSQAAAE 583
           ++  +    N +K   F H      A +       ++   R+  +    S          
Sbjct: 126 LSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGA 185

Query: 584 RSK--TVILVKNLPAGTLAAQLQETFGHFGSLGRVLLPEGGITAIVEFLEPLEARKAFRH 641
           ++K  T + +KN         L+E F  FG             ++    +P    K F  
Sbjct: 186 KAKEFTNVYIKNFGEEVDDESLKELFSQFGKT----------LSVKVMRDPNGKSKGFGF 235

Query: 642 LAYSKFHHVPLYLEWAPVGVFSSTAPQKKKLQDTPSEPMEKDPAEPETVPDGETPEDENP 701
           ++Y K                           +   E M       + +  G        
Sbjct: 236 VSYEKHEDA-----------------------NKAVEEMNGKEISGKIIFVGRA------ 266

Query: 702 TEEGADNSSAKMEEEEEEEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSI 761
            ++  +  +    + E+ ++E      G  L+IKNL+    +EKL++ FS  G++ S  +
Sbjct: 267 -QKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKV 325

Query: 762 SKKKNKAGVLLSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKLEVRISER 811
             +  +     S GFGFV +  PE+A KA+ ++ G +V    L V +++R
Sbjct: 326 MLEDGR-----SKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQR 370



 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 52/208 (25%), Positives = 104/208 (50%), Gaps = 18/208 (8%)

Query: 280 ETEKPANQKEPTTCHTVKLRGAPFNVTEKNVMEFLAPL-KPVAIRIVRNAHGNKTGYIFV 338
           E E  A  KE T    V ++     V ++++ E  +   K ++++++R+ +G   G+ FV
Sbjct: 180 EAELGAKAKEFTN---VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFV 236

Query: 339 DFSNEEEVKQALK-CNREYMGGRYIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEED 397
            +   E+  +A++  N + + G+ I V R         A K   +  + +   E  ++E 
Sbjct: 237 SYEKHEDANKAVEEMNGKEISGKIIFVGR---------AQKKVERQAELKRKFEQLKQER 287

Query: 398 LA--ESGRLFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEH 455
           ++  +   L+++NL  T  +E L K FS +G ++     ++    + KGF F+ F  PE 
Sbjct: 288 ISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEE 345

Query: 456 AVKAYSEVDGQVFQGRMLHVLPSTIKKE 483
           A KA +E++G++   + L+V  +  K+E
Sbjct: 346 ATKAVTEMNGRIVGSKPLYVALAQRKEE 373



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 41/169 (24%), Positives = 82/169 (48%), Gaps = 17/169 (10%)

Query: 726 SLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPE 785
           S P  +L++ +L+ D TE  L E FS  G V S  + +         S+G+ +V +++P 
Sbjct: 7   SYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRR---SLGYAYVNFQQPA 63

Query: 786 QAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIPFQAHS 845
            A++AL  +   V+ G  + +  S+R   P++         RK     + ++N+     +
Sbjct: 64  DAERALDTMNFDVIKGKPIRIMWSQR--DPSL---------RKSGVGNVFIKNLDKSIDN 112

Query: 846 REIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNAL 894
           + + + FS FG + + ++     G+   +G+ FV F T++ A +A   +
Sbjct: 113 KALYDTFSAFGNILSCKVVCDENGS---KGYAFVHFETQEAADKAIEKM 158



 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 24/71 (33%), Positives = 41/71 (57%), Gaps = 1/71 (1%)

Query: 4   LIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKHFN 63
           L +KNL + + +E+ R+ F+ FG++T   +   +DG+ + FGF+ F S EEA KA    N
Sbjct: 296 LYIKNLDDTIDDEKLRKEFSPFGSITSAKVML-EDGRSKGFGFVCFSSPEEATKAVTEMN 354

Query: 64  KSFIDTSRITV 74
              + +  + V
Sbjct: 355 GRIVGSKPLYV 365



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 17/62 (27%), Positives = 33/62 (53%)

Query: 2   SRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKH 61
           + + +KN    + +E  ++LF+ FG      +    +GK + FGF+ ++  E+A KA + 
Sbjct: 191 TNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEE 250

Query: 62  FN 63
            N
Sbjct: 251 MN 252



 Score = 38.5 bits (88), Expect = 0.030
 Identities = 19/79 (24%), Positives = 40/79 (50%), Gaps = 1/79 (1%)

Query: 1   MSRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQK 60
           +  + +KNL   +  +     F+AFG +  C +   ++G  + + F+ F+++E A KA +
Sbjct: 98  VGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGS-KGYAFVHFETQEAADKAIE 156

Query: 61  HFNKSFIDTSRITVEFCKS 79
             N   ++  ++ V   KS
Sbjct: 157 KMNGMLLNDRKVFVGRFKS 175


>gi|55956788 nucleolin [Homo sapiens]
          Length = 710

 Score = 80.5 bits (197), Expect = 7e-15
 Identities = 87/395 (22%), Positives = 169/395 (42%), Gaps = 39/395 (9%)

Query: 128 KEDTEFQEFLSVHQRRAQAATWANDGLDAEPSKGKSKPASDYLNFDSDSGQESEEEGAG- 186
           KED++ +E     +          D  + EP+  K+  A+     + D   E +E+    
Sbjct: 142 KEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDD 201

Query: 187 -EDLEEEASLEPKAAVQKELSDMDYLKSKMVKAGSSSSSEEEESEDEAVHCDEGSEAEEE 245
            ED  EE ++E   A  K+ + +  +K+K V        ++E+ +D+    DE  + E++
Sbjct: 202 EEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDD 261

Query: 246 DSSATPVLQERDSKGAGQEQGMPAGKKRPPEARAETEKPANQKEPTTCHTVKLRGAPFNV 305
           +       +E   +  G+ +   A +K  PEA+   ++     EPTT   + +    FN 
Sbjct: 262 EEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAK---KQKVEGTEPTTAFNLFVGNLNFNK 318

Query: 306 TEKNVMEFLAPL---KPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCNREYMGGRYI 362
           +   +   ++ +     +A+  VR     K GY  VDF + E++++AL+     + G  I
Sbjct: 319 SAPELKTGISDVFAKNDLAVVDVRIGMTRKFGY--VDFESAEDLEKALELTGLKVFGNEI 376

Query: 363 EVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEKLF 422
           ++ + K                     G++ ++E   ++  L  +NLPY  T+++L+++F
Sbjct: 377 KLEKPK---------------------GKDSKKE--RDARTLLAKNLPYKVTQDELKEVF 413

Query: 423 SKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHVLPSTIKK 482
                +      + S   K KG A+I F     A K + E  G    GR +  L  T +K
Sbjct: 414 EDAAEIR-----LVSKDGKSKGIAYIEFKTEADAEKTFEEKQGTEIDGRSIS-LYYTGEK 467

Query: 483 EASEDASALGSSSYKKKKEAQDKANSASSHNWNTL 517
             ++D     +S++  + +    +N + S    TL
Sbjct: 468 GQNQDYRGGKNSTWSGESKTLVLSNLSYSATEETL 502



 Score = 76.3 bits (186), Expect = 1e-13
 Identities = 66/272 (24%), Positives = 117/272 (43%), Gaps = 52/272 (19%)

Query: 665 TAPQKKKLQDTPSEPMEKDPAEPETVPDGETPEDENPTEEGADNSSAKMEEEEEEEEEEE 724
           T P K K          K+ AE E   + +  ED++  E+  D+     EEEEEEEEEE 
Sbjct: 213 TTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEP 272

Query: 725 -----------------------------ESLPGCTLFIKNLNFDTTEEKLKEVFSKVGT 755
                                        E      LF+ NLNF+ +  +LK   S V  
Sbjct: 273 VKEAPGKRKKEMAKQKAAPEAKKQKVEGTEPTTAFNLFVGNLNFNKSAPELKTGISDVFA 332

Query: 756 VKSCSISKKKNKAGVLLSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKLEVRISERATKP 815
               ++   +    + ++  FG+V++   E  +KAL +L G  V G+++++       KP
Sbjct: 333 KNDLAVVDVR----IGMTRKFGYVDFESAEDLEKAL-ELTGLKVFGNEIKLE------KP 381

Query: 816 AVTLARKKQVPRKQTTSKILVRNIPFQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRG 875
                + K   +++    +L +N+P++    E++E+F    E++ V      +  G  +G
Sbjct: 382 -----KGKDSKKERDARTLLAKNLPYKVTQDELKEVFEDAAEIRLV------SKDGKSKG 430

Query: 876 FGFVDFLTKQDAKRAFNALCHSTHLYGRRLVL 907
             +++F T+ DA++ F      T + GR + L
Sbjct: 431 IAYIEFKTEADAEKTFEEK-QGTEIDGRSISL 461



 Score = 70.1 bits (170), Expect = 9e-12
 Identities = 48/180 (26%), Positives = 84/180 (46%), Gaps = 21/180 (11%)

Query: 731 TLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPEQAQKA 790
           TL + NL++  TEE L+EVF K   +K       K+K       G+ F+E+   E A++A
Sbjct: 487 TLVLSNLSYSATEETLQEVFEKATFIKVPQNQNGKSK-------GYAFIEFASFEDAKEA 539

Query: 791 LKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIPFQAHSREIRE 850
           L       ++G  + + +      P           R Q +  + V+ +        ++E
Sbjct: 540 LNSCNKREIEGRAIRLELQGPRGSPNA---------RSQPSKTLFVKGLSEDTTEETLKE 590

Query: 851 LFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNALCHSTHLYGRRLVLEWA 910
            F   G ++   +  + TG+   +GFGFVDF +++DAK A  A+     + G ++ L+WA
Sbjct: 591 SFD--GSVRARIVTDRETGSS--KGFGFVDFNSEEDAKAAKEAM-EDGEIDGNKVTLDWA 645



 Score = 67.8 bits (164), Expect = 5e-11
 Identities = 46/197 (23%), Positives = 95/197 (48%), Gaps = 17/197 (8%)

Query: 712 KMEEEEEEEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVL 771
           K+E+ + ++ ++E      TL  KNL +  T+++LKEVF     ++  S   K       
Sbjct: 377 KLEKPKGKDSKKERDAR--TLLAKNLPYKVTQDELKEVFEDAAEIRLVSKDGK------- 427

Query: 772 LSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTT 831
            S G  ++E++    A+K  ++ QG  +DG  + +  +    +       K      ++ 
Sbjct: 428 -SKGIAYIEFKTEADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQDYRGGKNSTWSGESK 486

Query: 832 SKILVRNIPFQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAF 891
           + +L  N+ + A    ++E+F    +   +++P+   G    +G+ F++F + +DAK A 
Sbjct: 487 TLVL-SNLSYSATEETLQEVFE---KATFIKVPQNQNGKS--KGYAFIEFASFEDAKEAL 540

Query: 892 NALCHSTHLYGRRLVLE 908
           N+ C+   + GR + LE
Sbjct: 541 NS-CNKREIEGRAIRLE 556



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 94/402 (23%), Positives = 157/402 (39%), Gaps = 57/402 (14%)

Query: 94  QKPSQPKQPPKDSTTPEIKKDEKKKKVAGQLEKLKED-----TEFQEF---LSVHQRRAQ 145
           ++  + ++ P      + KK+  K+K A + +K K +     T F  F   L+ ++   +
Sbjct: 263 EEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEGTEPTTAFNLFVGNLNFNKSAPE 322

Query: 146 AAT-----WANDGLDAEPSKGKSKPASDYLNFDSDSGQESEEEGAG-EDLEEEASLE-PK 198
             T     +A + L     +        Y++F+S    E   E  G +    E  LE PK
Sbjct: 323 LKTGISDVFAKNDLAVVDVRIGMTRKFGYVDFESAEDLEKALELTGLKVFGNEIKLEKPK 382

Query: 199 AAVQKELSDMDYLKSKMVKAGSSSSSEEEESEDEAVHCDEGSEAEEEDSSATPVLQERDS 258
               K+  D   L +K +    +    +E  ED A       + + +  +      E D+
Sbjct: 383 GKDSKKERDARTLLAKNLPYKVTQDELKEVFEDAAEIRLVSKDGKSKGIAYIEFKTEADA 442

Query: 259 KGAGQEQGMPAGKKRPPEARAETEKPANQ-----KEPT---TCHTVKLRGAPFNVTEKNV 310
           +   +E+       R        EK  NQ     K  T      T+ L    ++ TE+ +
Sbjct: 443 EKTFEEKQGTEIDGRSISLYYTGEKGQNQDYRGGKNSTWSGESKTLVLSNLSYSATEETL 502

Query: 311 MEFLAPLKPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQAL-KCNREYMGGRYI--EVFRE 367
            E     K   I++ +N +G   GY F++F++ E+ K+AL  CN+  + GR I  E+   
Sbjct: 503 QEVFE--KATFIKVPQNQNGKSKGYAFIEFASFEDAKEALNSCNKREIEGRAIRLELQGP 560

Query: 368 KNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEKLFSKYGP 427
           +  P  +  P  T                       LFV+ L   +TEE L++ F   G 
Sbjct: 561 RGSPNARSQPSKT-----------------------LFVKGLSEDTTEETLKESFD--GS 595

Query: 428 LSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEV--DGQV 467
           +       D  T   KGF F+ F   E A KA  E   DG++
Sbjct: 596 V-RARIVTDRETGSSKGFGFVDFNSEEDA-KAAKEAMEDGEI 635



 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 31/98 (31%), Positives = 55/98 (56%), Gaps = 6/98 (6%)

Query: 707 DNSSAKMEEEEEEEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKN 766
           +  + ++E +         S P  TLF+K L+ DTTEE LKE F   G+V++  ++ ++ 
Sbjct: 549 EGRAIRLELQGPRGSPNARSQPSKTLFVKGLSEDTTEETLKESFD--GSVRARIVTDRET 606

Query: 767 KAGVLLSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKL 804
            +    S GFGFV++   E A+ A + ++   +DG+K+
Sbjct: 607 GS----SKGFGFVDFNSEEDAKAAKEAMEDGEIDGNKV 640



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 51/203 (25%), Positives = 90/203 (44%), Gaps = 25/203 (12%)

Query: 276 EARAETEKPANQKEPTTCHTVKLRGAPFNVTEKNVMEFLAPLKPVAIRIVRNAHGNKTGY 335
           E + E  K  + K+     T+  +  P+ VT+  + E         IR+V +  G   G 
Sbjct: 375 EIKLEKPKGKDSKKERDARTLLAKNLPYKVTQDELKEVFEDA--AEIRLV-SKDGKSKGI 431

Query: 336 IFVDFSNEEEVKQALKCNR-EYMGGRYIEVFR--EKNVPTTKGAPKNTTKSWQGRILGEN 392
            +++F  E + ++  +  +   + GR I ++   EK         KN+T  W G      
Sbjct: 432 AYIEFKTEADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQDYRGGKNST--WSG------ 483

Query: 393 EEEEDLAESGRLFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMF 452
                  ES  L + NL Y++TEE L+++F K    + +  P  +   K KG+AFI F  
Sbjct: 484 -------ESKTLVLSNLSYSATEETLQEVFEK---ATFIKVP-QNQNGKSKGYAFIEFAS 532

Query: 453 PEHAVKAYSEVDGQVFQGRMLHV 475
            E A +A +  + +  +GR + +
Sbjct: 533 FEDAKEALNSCNKREIEGRAIRL 555



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 23/79 (29%), Positives = 42/79 (53%), Gaps = 2/79 (2%)

Query: 4   LIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKHFN 63
           L VK L     EE  ++ F   G++    +   + G  + FGF+ F SEE+A+ A++   
Sbjct: 574 LFVKGLSEDTTEETLKESFD--GSVRARIVTDRETGSSKGFGFVDFNSEEDAKAAKEAME 631

Query: 64  KSFIDTSRITVEFCKSFGD 82
              ID +++T+++ K  G+
Sbjct: 632 DGEIDGNKVTLDWAKPKGE 650



 Score = 35.8 bits (81), Expect = 0.20
 Identities = 57/266 (21%), Positives = 109/266 (40%), Gaps = 43/266 (16%)

Query: 666 APQKKKLQDTPSEPMEKDPAEPETVPDGETPEDENPTEEGADNSSAKMEEEEEEEEEEEE 725
           A   K  +   S+  E D +E +   D +  EDE+  E  A  ++A     E+E++E++E
Sbjct: 134 AKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDE 193

Query: 726 SLPGCTLFIKNLNFDTTEEKLKEV-------FSKVGTVKSCSISKKKNKAGVLLSMGFG- 777
                     +   D +EE+  E         +KV  VK+ ++++ +++           
Sbjct: 194 DDED----DDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDD 249

Query: 778 ----------FVEYRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPR 827
                       E  + E+ ++ +K+  G          R  E A + A   A+K++V  
Sbjct: 250 DEDDEDDDDEDDEEEEEEEEEEPVKEAPGK---------RKKEMAKQKAAPEAKKQKVEG 300

Query: 828 KQTTS--KILVRNIPFQAHSREIRELFSTF---GELKTVRLPKKMTGTGTHRGFGFVDFL 882
            + T+   + V N+ F   + E++   S      +L  V +   MT     R FG+VDF 
Sbjct: 301 TEPTTAFNLFVGNLNFNKSAPELKTGISDVFAKNDLAVVDVRIGMT-----RKFGYVDFE 355

Query: 883 TKQDAKRAFNALCHSTHLYGRRLVLE 908
           + +D ++A         ++G  + LE
Sbjct: 356 SAEDLEKALELT--GLKVFGNEIKLE 379



 Score = 34.3 bits (77), Expect = 0.57
 Identities = 58/280 (20%), Positives = 103/280 (36%), Gaps = 26/280 (9%)

Query: 4   LIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKHFN 63
           L+ KNLP  + ++  +++F     +   S    KDGK +   +I FK+E +A+K  +   
Sbjct: 395 LLAKNLPYKVTQDELKEVFEDAAEIRLVS----KDGKSKGIAYIEFKTEADAEKTFEEKQ 450

Query: 64  KSFIDTSRITVEFCKSFGD-----PAKPRAWSKHAQK--PSQPKQPPKDSTTPEIKKDEK 116
            + ID   I++ +    G        K   WS  ++    S       + T  E+ +   
Sbjct: 451 GTEIDGRSISLYYTGEKGQNQDYRGGKNSTWSGESKTLVLSNLSYSATEETLQEVFEKAT 510

Query: 117 KKKVAGQLEKLKEDTEFQEFLSVHQRRAQAATWANDGLDAEPSKGKSKPASDYLNFDSDS 176
             KV        +   F EF S    +    +     ++    + + +      N  S  
Sbjct: 511 FIKVPQNQNGKSKGYAFIEFASFEDAKEALNSCNKREIEGRAIRLELQGPRGSPNARSQP 570

Query: 177 GQESEEEGAGEDLEEEASLEPKAAVQKELSDMDYLKSKMVKAGSSSSSE-----EEESED 231
            +    +G  ED  EE   E         S    +++++V    + SS+     +  SE+
Sbjct: 571 SKTLFVKGLSEDTTEETLKE---------SFDGSVRARIVTDRETGSSKGFGFVDFNSEE 621

Query: 232 EAVHCDEGSEAEEEDSSATPVLQERDSKGAGQEQGMPAGK 271
           +A    E  E  E D +    L     KG G   G   G+
Sbjct: 622 DAKAAKEAMEDGEIDGNKV-TLDWAKPKGEGGFGGRGGGR 660



 Score = 32.3 bits (72), Expect = 2.2
 Identities = 19/59 (32%), Positives = 32/59 (54%), Gaps = 2/59 (3%)

Query: 670 KKLQDTPSEPMEKDPAEPETVPDGETPEDENPTEEGADNSSAKMEEEEEEEEEEEESLP 728
           K L  TP +     PA+     +G+  + E+  EE  D+S    E++E+E+E+E+E  P
Sbjct: 116 KALVATPGKKGAAIPAKG--AKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEP 172


>gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens]
          Length = 636

 Score = 80.1 bits (196), Expect = 9e-15
 Identities = 97/442 (21%), Positives = 179/442 (40%), Gaps = 77/442 (17%)

Query: 404 LFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEV 463
           L+V +L    TE  L + FS  GP+  +    D +T++  G+A++ F  P  A +A   +
Sbjct: 13  LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72

Query: 464 DGQVFQGRMLHVLPSTIKKEASEDASALGSSSYKKKKEAQDKANSASSHNWNTLFMGPNA 523
           +  V +G+ + ++ S  +++ S   S +G+   K   ++ D  N A    ++T     N 
Sbjct: 73  NFDVIKGKPVRIMWS--QRDPSLRKSGVGNIFIKNLDKSID--NKAL---YDTFSAFGNI 125

Query: 524 VADAIAQKYNATKSQVFDHETKGSVAVRVALGETQLVQEVRRFLIDNGVSLDSFSQAAAE 583
           ++  +    N +K   F H      A R       ++   R+  +    S          
Sbjct: 126 LSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAELGA 185

Query: 584 RSK--TVILVKNLPAGTLAAQLQETFGHFGSL--GRVLLPEGGIT---AIVEFLEPLEAR 636
           R+K  T + +KN        +L++ FG FG     +V+  E G +     V F    +A+
Sbjct: 186 RAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQ 245

Query: 637 KAFRHLAYSKFHHVPLYLEWAPVGVFSSTAPQKKKLQDTPSEPMEKDPAEPETVPDGETP 696
           KA   +   + +   +Y+  A   V   T  ++K                          
Sbjct: 246 KAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKF------------------------- 280

Query: 697 EDENPTEEGADNSSAKMEEEEEEEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTV 756
                               E+ +++      G  L++KNL+    +E+L++ FS  GT+
Sbjct: 281 --------------------EQMKQDRITRYQGVNLYVKNLDDGIDDERLRKEFSPFGTI 320

Query: 757 KSCSISKKKNKAGVLLSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPA 816
            S  +  +  +     S GFGFV +  PE+A KA+ ++ G +V            ATKP 
Sbjct: 321 TSAKVMMEGGR-----SKGFGFVCFSSPEEATKAVTEMNGRIV------------ATKPL 363

Query: 817 -VTLARKKQVPRKQTTSKILVR 837
            V LA++K+  +   T++ + R
Sbjct: 364 YVALAQRKEERQAHLTNQYMQR 385



 Score = 76.3 bits (186), Expect = 1e-13
 Identities = 52/180 (28%), Positives = 91/180 (50%), Gaps = 12/180 (6%)

Query: 716 EEEEEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMG 775
           +E E E    +     ++IKN   D  +E+LK++F K G   S  +   ++      S G
Sbjct: 177 KEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGK----SKG 232

Query: 776 FGFVEYRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARK-KQVPRKQTTS-- 832
           FGFV + + E AQKA+ ++ G  ++G ++ V  +++  +    L RK +Q+ + + T   
Sbjct: 233 FGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQ 292

Query: 833 --KILVRNIPFQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRA 890
              + V+N+        +R+ FS FG   T+   K M   G  +GFGFV F + ++A +A
Sbjct: 293 GVNLYVKNLDDGIDDERLRKEFSPFG---TITSAKVMMEGGRSKGFGFVCFSSPEEATKA 349



 Score = 75.5 bits (184), Expect = 2e-13
 Identities = 55/194 (28%), Positives = 100/194 (51%), Gaps = 18/194 (9%)

Query: 732 LFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPEQAQKAL 791
           +FIKNL+     + L + FS  G + SC +   +N      S G+GFV +   E A++A+
Sbjct: 101 IFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG-----SKGYGFVHFETQEAAERAI 155

Query: 792 KQLQGHVVDGHKLEV-RISERATKPAVTLARKKQVPRKQTTSKILVRNIPFQAHSREIRE 850
           +++ G +++  K+ V R   R  + A   AR K+       + + ++N         +++
Sbjct: 156 EKMNGMLLNDRKVFVGRFKSRKEREAELGARAKEF------TNVYIKNFGEDMDDERLKD 209

Query: 851 LFSTFGELKTVRLPKKMTG-TGTHRGFGFVDFLTKQDAKRAFNALCHSTHLYGRRLVLEW 909
           LF  FG   +V++   MT  +G  +GFGFV F   +DA++A + + +   L G+++ +  
Sbjct: 210 LFGKFGPALSVKV---MTDESGKSKGFGFVSFERHEDAQKAVDEM-NGKELNGKQIYVGR 265

Query: 910 ADSEVTLQA-LRRK 922
           A  +V  Q  L+RK
Sbjct: 266 AQKKVERQTELKRK 279



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 43/169 (25%), Positives = 84/169 (49%), Gaps = 17/169 (10%)

Query: 726 SLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPE 785
           S P  +L++ +L+ D TE  L E FS  G + S  + +         S+G+ +V +++P 
Sbjct: 7   SYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRR---SLGYAYVNFQQPA 63

Query: 786 QAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIPFQAHS 845
            A++AL  +   V+ G  + +  S+R   P++         RK     I ++N+     +
Sbjct: 64  DAERALDTMNFDVIKGKPVRIMWSQR--DPSL---------RKSGVGNIFIKNLDKSIDN 112

Query: 846 REIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNAL 894
           + + + FS FG + + ++     G+   +G+GFV F T++ A+RA   +
Sbjct: 113 KALYDTFSAFGNILSCKVVCDENGS---KGYGFVHFETQEAAERAIEKM 158



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 51/207 (24%), Positives = 98/207 (47%), Gaps = 16/207 (7%)

Query: 280 ETEKPANQKEPTTCHTVKLRGAPFNVTEKNVMEFLAPLKP-VAIRIVRNAHGNKTGYIFV 338
           E E  A  KE T    V ++    ++ ++ + +      P ++++++ +  G   G+ FV
Sbjct: 180 EAELGARAKEFTN---VYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFV 236

Query: 339 DFSNEEEVKQAL-KCNREYMGGRYIEVFR-EKNVPTTKGAPKNTTKSWQGRILGENEEEE 396
            F   E+ ++A+ + N + + G+ I V R +K V       +   +  Q RI        
Sbjct: 237 SFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRY----- 291

Query: 397 DLAESGRLFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHA 456
              +   L+V+NL     +E L K FS +G ++     ++    + KGF F+ F  PE A
Sbjct: 292 ---QGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEG--GRSKGFGFVCFSSPEEA 346

Query: 457 VKAYSEVDGQVFQGRMLHVLPSTIKKE 483
            KA +E++G++   + L+V  +  K+E
Sbjct: 347 TKAVTEMNGRIVATKPLYVALAQRKEE 373



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 28/71 (39%), Positives = 41/71 (57%), Gaps = 1/71 (1%)

Query: 4   LIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKHFN 63
           L VKNL +G+ +ER R+ F+ FGT+T   +   + G+ + FGF+ F S EEA KA    N
Sbjct: 296 LYVKNLDDGIDDERLRKEFSPFGTITSAKV-MMEGGRSKGFGFVCFSSPEEATKAVTEMN 354

Query: 64  KSFIDTSRITV 74
              + T  + V
Sbjct: 355 GRIVATKPLYV 365



 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 23/73 (31%), Positives = 37/73 (50%)

Query: 2   SRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKH 61
           + + +KN    M +ER + LF  FG      +   + GK + FGF+ F+  E+AQKA   
Sbjct: 191 TNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDE 250

Query: 62  FNKSFIDTSRITV 74
            N   ++  +I V
Sbjct: 251 MNGKELNGKQIYV 263



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 85/377 (22%), Positives = 147/377 (38%), Gaps = 52/377 (13%)

Query: 304 NVTEKNVMEFLAPLKPV-AIRIVRNAHGNKT-GYIFVDFSNEEEVKQALKCNREYMGGRY 361
           +VTE  + E  +P  P+ +IR+ R+    ++ GY +V+F    + ++AL           
Sbjct: 21  DVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDT--------- 71

Query: 362 IEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESG--RLFVRNLPYTSTEEDLE 419
                  N    KG P     S         + +  L +SG   +F++NL  +   + L 
Sbjct: 72  ------MNFDVIKGKPVRIMWS---------QRDPSLRKSGVGNIFIKNLDKSIDNKALY 116

Query: 420 KLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHV--LP 477
             FS +G +       D      KG+ F+ F   E A +A  +++G +   R + V    
Sbjct: 117 DTFSAFGNILSCKVVCDE--NGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFK 174

Query: 478 STIKKEASEDASALGSSSYKKKKEAQD-----------KANSASSHNWNTLFMGPNAVAD 526
           S  ++EA   A A   ++   K   +D           K   A S    T   G +    
Sbjct: 175 SRKEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFG 234

Query: 527 AIA-QKYNATKSQVFDHETKGSVAVRVALGETQLVQEVRRFLIDNGVSLDSFSQAAAERS 585
            ++ +++   +  V +   K     ++ +G  Q   E +  L       +   Q    R 
Sbjct: 235 FVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTEL---KRKFEQMKQDRITRY 291

Query: 586 KTV-ILVKNLPAGTLAAQLQETFGHFGSL-GRVLLPEGGIT---AIVEFLEPLEARKAFR 640
           + V + VKNL  G    +L++ F  FG++    ++ EGG +     V F  P EA KA  
Sbjct: 292 QGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVT 351

Query: 641 HLAYSKFHHVPLYLEWA 657
            +        PLY+  A
Sbjct: 352 EMNGRIVATKPLYVALA 368



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 19/79 (24%), Positives = 42/79 (53%), Gaps = 1/79 (1%)

Query: 1   MSRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQK 60
           +  + +KNL   +  +     F+AFG +  C +   ++G  + +GF+ F+++E A++A +
Sbjct: 98  VGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGS-KGYGFVHFETQEAAERAIE 156

Query: 61  HFNKSFIDTSRITVEFCKS 79
             N   ++  ++ V   KS
Sbjct: 157 KMNGMLLNDRKVFVGRFKS 175


>gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens]
          Length = 631

 Score = 77.8 bits (190), Expect = 5e-14
 Identities = 54/194 (27%), Positives = 99/194 (51%), Gaps = 17/194 (8%)

Query: 732 LFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPEQAQKAL 791
           +F+KNL+     + L +  S  G + SC++   +N      S G+GFV +   E A++A+
Sbjct: 101 IFVKNLDKSINNKALYDTVSAFGNILSCNVVCDENG-----SKGYGFVHFETHEAAERAI 155

Query: 792 KQLQGHVVDGHKLEV-RISERATKPAVTLARKKQVPRKQTTSKILVRNIPFQAHSREIRE 850
           K++ G +++G K+ V +   R  + A   AR K+ P       + ++N         +++
Sbjct: 156 KKMNGMLLNGRKVFVGQFKSRKEREAELGARAKEFP------NVYIKNFGEDMDDERLKD 209

Query: 851 LFSTFGELKTVRLPKKMTG-TGTHRGFGFVDFLTKQDAKRAFNALCHSTHLYGRRLVLEW 909
           LF  FG   +V   K MT  +G  +GFGFV F   +DA++A + + +   L G+++ +  
Sbjct: 210 LFGKFGPALSV---KVMTDESGKSKGFGFVSFERHEDAQKAVDEM-NGKELNGKQIYVGR 265

Query: 910 ADSEVTLQALRRKT 923
           A  +V  Q   ++T
Sbjct: 266 AQKKVERQTELKRT 279



 Score = 76.3 bits (186), Expect = 1e-13
 Identities = 56/183 (30%), Positives = 92/183 (50%), Gaps = 16/183 (8%)

Query: 714 EEEEEEEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLS 773
           +E E E     +  P   ++IKN   D  +E+LK++F K G   S  +   ++      S
Sbjct: 177 KEREAELGARAKEFPN--VYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGK----S 230

Query: 774 MGFGFVEYRKPEQAQKALKQLQGHVVDGHKLEV----RISERATKPAVTLARKKQ--VPR 827
            GFGFV + + E AQKA+ ++ G  ++G ++ V    +  ER T+   T  + KQ  + R
Sbjct: 231 KGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRTFEQMKQDRITR 290

Query: 828 KQTTSKILVRNIPFQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDA 887
            Q  + + V+N+        +R+ FS FG   T+   K M   G  +GFGFV F + ++A
Sbjct: 291 YQVVN-LYVKNLDDGIDDERLRKAFSPFG---TITSAKVMMEGGRSKGFGFVCFSSPEEA 346

Query: 888 KRA 890
            +A
Sbjct: 347 TKA 349



 Score = 68.2 bits (165), Expect = 4e-11
 Identities = 96/443 (21%), Positives = 176/443 (39%), Gaps = 79/443 (17%)

Query: 404 LFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEV 463
           L+V +L    TE  L + FS  GP+  +    D +T     +A++ F   + A  A   +
Sbjct: 13  LYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHTKDAEHALDTM 72

Query: 464 DGQVFQGRMLHVLPSTIKKEASEDASALGSSSYKK-KKEAQDKANSASSHNWNTLFMGPN 522
           +  V +G+ + ++ S  +++ S   S +G+   K   K   +KA       ++T+    N
Sbjct: 73  NFDVIKGKPVRIMWS--QRDPSLRKSGVGNIFVKNLDKSINNKAL------YDTVSAFGN 124

Query: 523 AVADAIAQKYNATKSQVFDHETKGSVAVRVALGETQLVQEVRRFLIDNGVSLDSFSQAAA 582
            ++  +    N +K   F H      A R       ++   R+  +    S         
Sbjct: 125 ILSCNVVCDENGSKGYGFVHFETHEAAERAIKKMNGMLLNGRKVFVGQFKSRKEREAELG 184

Query: 583 ERSKTV--ILVKNLPAGTLAAQLQETFGHFGSL--GRVLLPEGGIT---AIVEFLEPLEA 635
            R+K    + +KN        +L++ FG FG     +V+  E G +     V F    +A
Sbjct: 185 ARAKEFPNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDA 244

Query: 636 RKAFRHLAYSKFHHVPLYLEWAPVGVFSSTAPQKKKLQDTPSEPMEKDPAEPETVPDGET 695
           +KA   +   + +   +Y     VG       ++ +L+ T  E M++D      V +   
Sbjct: 245 QKAVDEMNGKELNGKQIY-----VGRAQKKVERQTELKRT-FEQMKQDRITRYQVVN--- 295

Query: 696 PEDENPTEEGADNSSAKMEEEEEEEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGT 755
                                               L++KNL+    +E+L++ FS  GT
Sbjct: 296 ------------------------------------LYVKNLDDGIDDERLRKAFSPFGT 319

Query: 756 VKSCSISKKKNKAGVLLSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKLEVRISERATKP 815
           + S  +  +  +     S GFGFV +  PE+A KA+ ++ G +V            ATKP
Sbjct: 320 ITSAKVMMEGGR-----SKGFGFVCFSSPEEATKAVTEMNGRIV------------ATKP 362

Query: 816 A-VTLARKKQVPRKQTTSKILVR 837
             V LA++K+  +   T++ + R
Sbjct: 363 LYVALAQRKEERQAYLTNEYMQR 385



 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 46/180 (25%), Positives = 86/180 (47%), Gaps = 18/180 (10%)

Query: 726 SLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPE 785
           S P  +L++ +L+ D TE  L E FS  G + S  I +    +G   S  + +V ++  +
Sbjct: 7   SYPTASLYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSG---SSNYAYVNFQHTK 63

Query: 786 QAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIPFQAHS 845
            A+ AL  +   V+ G  + +  S+R   P++         RK     I V+N+    ++
Sbjct: 64  DAEHALDTMNFDVIKGKPVRIMWSQR--DPSL---------RKSGVGNIFVKNLDKSINN 112

Query: 846 REIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNALCHSTHLYGRRL 905
           + + +  S FG + +  +     G+   +G+GFV F T + A+RA   + +   L GR++
Sbjct: 113 KALYDTVSAFGNILSCNVVCDENGS---KGYGFVHFETHEAAERAIKKM-NGMLLNGRKV 168



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 40/165 (24%), Positives = 82/165 (49%), Gaps = 10/165 (6%)

Query: 320 VAIRIVRNAHGNKTGYIFVDFSNEEEVKQAL-KCNREYMGGRYIEVFREKNVPTTKGAPK 378
           ++++++ +  G   G+ FV F   E+ ++A+ + N + + G+ I V R +     +   K
Sbjct: 218 LSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELK 277

Query: 379 NTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSL 438
            T +  +       ++     +   L+V+NL     +E L K FS +G ++     ++  
Sbjct: 278 RTFEQMK-------QDRITRYQVVNLYVKNLDDGIDDERLRKAFSPFGTITSAKVMMEG- 329

Query: 439 TKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHVLPSTIKKE 483
             + KGF F+ F  PE A KA +E++G++   + L+V  +  K+E
Sbjct: 330 -GRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEE 373



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 42/160 (26%), Positives = 71/160 (44%), Gaps = 26/160 (16%)

Query: 320 VAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCNREYMGGRYIEVFREKNVPTTKGAPKN 379
           ++  +V + +G+K GY FV F   E  ++A+K                       G   N
Sbjct: 126 LSCNVVCDENGSK-GYGFVHFETHEAAERAIK--------------------KMNGMLLN 164

Query: 380 TTKSWQGRILGENEEEEDLA----ESGRLFVRNLPYTSTEEDLEKLFSKYGPLSELHYPI 435
             K + G+     E E +L     E   ++++N      +E L+ LF K+GP   +    
Sbjct: 165 GRKVFVGQFKSRKEREAELGARAKEFPNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMT 224

Query: 436 DSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHV 475
           D  + K KGF F++F   E A KA  E++G+   G+ ++V
Sbjct: 225 DE-SGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYV 263



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 28/71 (39%), Positives = 41/71 (57%), Gaps = 1/71 (1%)

Query: 4   LIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKHFN 63
           L VKNL +G+ +ER R+ F+ FGT+T   +   + G+ + FGF+ F S EEA KA    N
Sbjct: 296 LYVKNLDDGIDDERLRKAFSPFGTITSAKV-MMEGGRSKGFGFVCFSSPEEATKAVTEMN 354

Query: 64  KSFIDTSRITV 74
              + T  + V
Sbjct: 355 GRIVATKPLYV 365



 Score = 47.4 bits (111), Expect = 7e-05
 Identities = 23/69 (33%), Positives = 35/69 (50%)

Query: 6   VKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKHFNKS 65
           +KN    M +ER + LF  FG      +   + GK + FGF+ F+  E+AQKA    N  
Sbjct: 195 IKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGK 254

Query: 66  FIDTSRITV 74
            ++  +I V
Sbjct: 255 ELNGKQIYV 263



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 83/377 (22%), Positives = 145/377 (38%), Gaps = 52/377 (13%)

Query: 304 NVTEKNVMEFLAPLKPV-AIRIVRNA-HGNKTGYIFVDFSNEEEVKQALKCNREYMGGRY 361
           +VTE  + E  +P  P+ +IRI R+      + Y +V+F + ++ + AL           
Sbjct: 21  DVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHTKDAEHALDT--------- 71

Query: 362 IEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESG--RLFVRNLPYTSTEEDLE 419
                  N    KG P     S         + +  L +SG   +FV+NL  +   + L 
Sbjct: 72  ------MNFDVIKGKPVRIMWS---------QRDPSLRKSGVGNIFVKNLDKSINNKALY 116

Query: 420 KLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHVLPST 479
              S +G +   +   D      KG+ F+ F   E A +A  +++G +  GR + V    
Sbjct: 117 DTVSAFGNILSCNVVCDE--NGSKGYGFVHFETHEAAERAIKKMNGMLLNGRKVFVGQFK 174

Query: 480 IKKEASEDASALGSS-------------SYKKKKEAQDKANSASSHNWNTLFMGPNAVAD 526
            +KE   +  A                   ++ K+   K   A S    T   G +    
Sbjct: 175 SRKEREAELGARAKEFPNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFG 234

Query: 527 AIA-QKYNATKSQVFDHETKGSVAVRVALGETQLVQEVRRFLIDNGVSLDSFSQAAAERS 585
            ++ +++   +  V +   K     ++ +G  Q   E +  L     + +   Q    R 
Sbjct: 235 FVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTEL---KRTFEQMKQDRITRY 291

Query: 586 KTV-ILVKNLPAGTLAAQLQETFGHFGSL-GRVLLPEGGIT---AIVEFLEPLEARKAFR 640
           + V + VKNL  G    +L++ F  FG++    ++ EGG +     V F  P EA KA  
Sbjct: 292 QVVNLYVKNLDDGIDDERLRKAFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVT 351

Query: 641 HLAYSKFHHVPLYLEWA 657
            +        PLY+  A
Sbjct: 352 EMNGRIVATKPLYVALA 368



 Score = 39.7 bits (91), Expect = 0.014
 Identities = 20/79 (25%), Positives = 41/79 (51%), Gaps = 1/79 (1%)

Query: 1   MSRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQK 60
           +  + VKNL   +  +      +AFG +  C++   ++G  + +GF+ F++ E A++A K
Sbjct: 98  VGNIFVKNLDKSINNKALYDTVSAFGNILSCNVVCDENGS-KGYGFVHFETHEAAERAIK 156

Query: 61  HFNKSFIDTSRITVEFCKS 79
             N   ++  ++ V   KS
Sbjct: 157 KMNGMLLNGRKVFVGQFKS 175


>gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo
           sapiens]
          Length = 370

 Score = 77.8 bits (190), Expect = 5e-14
 Identities = 52/184 (28%), Positives = 95/184 (51%), Gaps = 12/184 (6%)

Query: 716 EEEEEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMG 775
           ++ E E   ++     ++IKN   D  +E+LK+VFSK G  K+ S+    + +G   S G
Sbjct: 176 KDREAELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYG--KTLSVKVMTDSSG--KSKG 231

Query: 776 FGFVEYRKPEQAQKALKQLQGHVVDGHKLEV-RISERATKPAVTLARKKQVPRKQTTS-- 832
           FGFV +   E A+KA++++ G  ++G  + V R  ++  + A      +Q+ R++     
Sbjct: 232 FGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQ 291

Query: 833 --KILVRNIPFQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRA 890
             K+ ++N+       ++R  FS+FG +  V   K M   G  +GFG + F + +DA +A
Sbjct: 292 GVKLYIKNLDDTIDDEKLRNEFSSFGSISRV---KVMQEEGQSKGFGLICFSSPEDATKA 348

Query: 891 FNAL 894
              +
Sbjct: 349 MTEM 352



 Score = 57.8 bits (138), Expect = 5e-08
 Identities = 41/161 (25%), Positives = 80/161 (49%), Gaps = 14/161 (8%)

Query: 318 KPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALK-CNREYMGGRYIEVFREKNVPTTKGA 376
           K ++++++ ++ G   G+ FV F + E  K+A++  N   + G+ I V R         A
Sbjct: 215 KTLSVKVMTDSSGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGR---------A 265

Query: 377 PKNTTKSWQGRILGENEEEEDL--AESGRLFVRNLPYTSTEEDLEKLFSKYGPLSELHYP 434
            K   +  + + + E  + E +   +  +L+++NL  T  +E L   FS +G +S +   
Sbjct: 266 QKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDDTIDDEKLRNEFSSFGSISRVKVM 325

Query: 435 IDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHV 475
            +    + KGF  I F  PE A KA +E++G++   + L +
Sbjct: 326 QEE--GQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSI 364



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 49/177 (27%), Positives = 85/177 (48%), Gaps = 27/177 (15%)

Query: 304 NVTEKNVME-FLAPLKPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCNREYMGGRYI 362
           ++  K + E F A  K ++ +++ +  G+K GY FV F N+    +A+    E M G+ +
Sbjct: 108 SIDNKTLYEHFSAFGKILSSKVMSDDQGSK-GYAFVHFQNQSAADRAI----EEMNGKLL 162

Query: 363 EVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDL----AESGRLFVRNLPYTSTEEDL 418
                      KG      K + GR     + E +L    +E   ++++N      +E L
Sbjct: 163 -----------KGC-----KVFVGRFKNRKDREAELRSKASEFTNVYIKNFGGDMDDERL 206

Query: 419 EKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHV 475
           + +FSKYG    +    DS + K KGF F++F   E A KA  E++G+   G+++ V
Sbjct: 207 KDVFSKYGKTLSVKVMTDS-SGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFV 262



 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 40/164 (24%), Positives = 75/164 (45%), Gaps = 17/164 (10%)

Query: 731 TLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPEQAQKA 790
           +L++ +L+ D TE+ L   FS VG V S  I + +       S+G+ +V + +   AQKA
Sbjct: 11  SLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRR---SLGYAYVNFLQLADAQKA 67

Query: 791 LKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIPFQAHSREIRE 850
           L  +   ++ G  + +  S+R               R+     + ++N+     ++ + E
Sbjct: 68  LDTMNFDIIKGKSIRLMWSQR-----------DAYLRRSGIGNVFIKNLDKSIDNKTLYE 116

Query: 851 LFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNAL 894
            FS FG++ +    K M+     +G+ FV F  +  A RA   +
Sbjct: 117 HFSAFGKILS---SKVMSDDQGSKGYAFVHFQNQSAADRAIEEM 157



 Score = 53.5 bits (127), Expect = 9e-07
 Identities = 27/95 (28%), Positives = 52/95 (54%), Gaps = 8/95 (8%)

Query: 720 EEEEEESLPGCT---LFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGF 776
           E+ + E + GC    L+IKNL+    +EKL+  FS  G++    + +++ +     S GF
Sbjct: 280 EQLKRERIRGCQGVKLYIKNLDDTIDDEKLRNEFSSFGSISRVKVMQEEGQ-----SKGF 334

Query: 777 GFVEYRKPEQAQKALKQLQGHVVDGHKLEVRISER 811
           G + +  PE A KA+ ++ G ++    L + +++R
Sbjct: 335 GLICFSSPEDATKAMTEMNGRILGSKPLSIALAQR 369



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 22/73 (30%), Positives = 36/73 (49%)

Query: 2   SRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKH 61
           + + +KN    M +ER + +F+ +G      +     GK + FGF+ F S E A+KA + 
Sbjct: 190 TNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSHEAAKKAVEE 249

Query: 62  FNKSFIDTSRITV 74
            N   I+   I V
Sbjct: 250 MNGRDINGQLIFV 262



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 20/72 (27%), Positives = 42/72 (58%), Gaps = 1/72 (1%)

Query: 3   RLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKHF 62
           +L +KNL + + +E+ R  F++FG+++   +   ++G+ + FG I F S E+A KA    
Sbjct: 294 KLYIKNLDDTIDDEKLRNEFSSFGSISRVKV-MQEEGQSKGFGLICFSSPEDATKAMTEM 352

Query: 63  NKSFIDTSRITV 74
           N   + +  +++
Sbjct: 353 NGRILGSKPLSI 364



 Score = 39.7 bits (91), Expect = 0.014
 Identities = 50/218 (22%), Positives = 97/218 (44%), Gaps = 25/218 (11%)

Query: 404 LFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEV 463
           L+V +L    TE+ L + FS  GP+  +    D +T++  G+A++ F+    A KA   +
Sbjct: 12  LYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDTM 71

Query: 464 DGQVFQGRMLHVLPSTIKKEASEDASALGSSSYKKKKEAQDKANSASSHNWNTLFMGPNA 523
           +  + +G+ + ++ S  +++A    S +G+   K   ++ D           TL+   +A
Sbjct: 72  NFDIIKGKSIRLMWS--QRDAYLRRSGIGNVFIKNLDKSIDN---------KTLYEHFSA 120

Query: 524 VADAIAQKY----NATKSQVFDHETKGSVAVRVALGET--QLVQEVRRFLIDNGVSLDSF 577
               ++ K       +K   F H    S A R A+ E   +L++  + F+   G   +  
Sbjct: 121 FGKILSSKVMSDDQGSKGYAFVHFQNQSAADR-AIEEMNGKLLKGCKVFV---GRFKNRK 176

Query: 578 SQAAAERSK----TVILVKNLPAGTLAAQLQETFGHFG 611
            + A  RSK    T + +KN        +L++ F  +G
Sbjct: 177 DREAELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYG 214


>gi|55956921 heterogeneous nuclear ribonucleoprotein A/B isoform b
           [Homo sapiens]
          Length = 285

 Score = 77.4 bits (189), Expect = 6e-14
 Identities = 62/232 (26%), Positives = 102/232 (43%), Gaps = 33/232 (14%)

Query: 678 EPMEKDPAEP---ETVPDGETPEDENP-TEEGADNSSAK--------MEEEEEEEEEEEE 725
           +PME   A     E VP+GE+P         GA  ++A          E ++    + EE
Sbjct: 8   QPMETTGATENGHEAVPEGESPAGAGTGAAAGAGGATAAPPSGNQNGAEGDQINASKNEE 67

Query: 726 SLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPE 785
                 +F+  L++DT+++ LK+ F+K G V  C+I    N      S GFGF+ ++   
Sbjct: 68  DAG--KMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGR---SRGFGFILFKDAA 122

Query: 786 QAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIPFQAHS 845
             +K L Q +      H+L+ R+ +          +K    +K    KI V  +  +A  
Sbjct: 123 SVEKVLDQKE------HRLDGRVID---------PKKAMAMKKDPVKKIFVGGLNPEATE 167

Query: 846 REIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNALCHS 897
            +IRE F  FGE++ + LP         RGF F+ F  ++  K+      H+
Sbjct: 168 EKIREYFGEFGEIEAIELPMD-PKLNKRRGFVFITFKEEEPVKKVLEKKFHT 218



 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 49/227 (21%), Positives = 83/227 (36%), Gaps = 33/227 (14%)

Query: 238 EGSEAEEEDSSATPVLQERDSKGAGQEQGMPAGKKRPPEAR---AETEKPANQKEPTTCH 294
           E + A E    A P  +     G G   G       PP      AE ++    K      
Sbjct: 11  ETTGATENGHEAVPEGESPAGAGTGAAAGAGGATAAPPSGNQNGAEGDQINASKNEEDAG 70

Query: 295 TVKLRGAPFNVTEKNVMEFLAPLKPVA---IRIVRNAHGNKTGYIFVDFSNEEEVKQALK 351
            + + G  ++ ++K++ ++      V    I++  N  G   G+ F+ F +   V++ L 
Sbjct: 71  KMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNT-GRSRGFGFILFKDAASVEKVLD 129

Query: 352 CNREYMGGRYIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPY 411
                + GR I+    K     K  P                         ++FV  L  
Sbjct: 130 QKEHRLDGRVID---PKKAMAMKKDPVK-----------------------KIFVGGLNP 163

Query: 412 TSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVK 458
            +TEE + + F ++G +  +  P+D    K +GF FITF   E   K
Sbjct: 164 EATEEKIREYFGEFGEIEAIELPMDPKLNKRRGFVFITFKEEEPVKK 210



 Score = 33.1 bits (74), Expect = 1.3
 Identities = 17/56 (30%), Positives = 28/56 (50%), Gaps = 1/56 (1%)

Query: 3   RLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKD-GKFRKFGFIGFKSEEEAQK 57
           ++ V  L     ++  +  F  FG + DC++K   + G+ R FGFI FK     +K
Sbjct: 71  KMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKDAASVEK 126


>gi|55956919 heterogeneous nuclear ribonucleoprotein A/B isoform a
           [Homo sapiens]
          Length = 332

 Score = 77.4 bits (189), Expect = 6e-14
 Identities = 62/232 (26%), Positives = 102/232 (43%), Gaps = 33/232 (14%)

Query: 678 EPMEKDPAEP---ETVPDGETPEDENP-TEEGADNSSAK--------MEEEEEEEEEEEE 725
           +PME   A     E VP+GE+P         GA  ++A          E ++    + EE
Sbjct: 8   QPMETTGATENGHEAVPEGESPAGAGTGAAAGAGGATAAPPSGNQNGAEGDQINASKNEE 67

Query: 726 SLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPE 785
                 +F+  L++DT+++ LK+ F+K G V  C+I    N      S GFGF+ ++   
Sbjct: 68  DAG--KMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGR---SRGFGFILFKDAA 122

Query: 786 QAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIPFQAHS 845
             +K L Q +      H+L+ R+ +          +K    +K    KI V  +  +A  
Sbjct: 123 SVEKVLDQKE------HRLDGRVID---------PKKAMAMKKDPVKKIFVGGLNPEATE 167

Query: 846 REIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNALCHS 897
            +IRE F  FGE++ + LP         RGF F+ F  ++  K+      H+
Sbjct: 168 EKIREYFGEFGEIEAIELPMD-PKLNKRRGFVFITFKEEEPVKKVLEKKFHT 218



 Score = 50.4 bits (119), Expect = 8e-06
 Identities = 57/287 (19%), Positives = 100/287 (34%), Gaps = 37/287 (12%)

Query: 238 EGSEAEEEDSSATPVLQERDSKGAGQEQGMPAGKKRPPEAR---AETEKPANQKEPTTCH 294
           E + A E    A P  +     G G   G       PP      AE ++    K      
Sbjct: 11  ETTGATENGHEAVPEGESPAGAGTGAAAGAGGATAAPPSGNQNGAEGDQINASKNEEDAG 70

Query: 295 TVKLRGAPFNVTEKNVMEFLAPLKPVA---IRIVRNAHGNKTGYIFVDFSNEEEVKQALK 351
            + + G  ++ ++K++ ++      V    I++  N  G   G+ F+ F +   V++ L 
Sbjct: 71  KMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNT-GRSRGFGFILFKDAASVEKVLD 129

Query: 352 CNREYMGGRYIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPY 411
                + GR I+    K     K  P                         ++FV  L  
Sbjct: 130 QKEHRLDGRVID---PKKAMAMKKDPVK-----------------------KIFVGGLNP 163

Query: 412 TSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGR 471
            +TEE + + F ++G +  +  P+D    K +GF FITF   E  VK   E       G 
Sbjct: 164 EATEEKIREYFGEFGEIEAIELPMDPKLNKRRGFVFITFK-EEEPVKKVLEKKFHTVSGS 222

Query: 472 MLHV---LPSTIKKEASEDASALGSSSYKKKKEAQDKANSASSHNWN 515
              +    P  + ++    +   G+ +   +           S +WN
Sbjct: 223 KCEIKVAQPKEVYQQQQYGSGGRGNRNRGNRGSGGGGGGGGQSQSWN 269



 Score = 33.1 bits (74), Expect = 1.3
 Identities = 17/56 (30%), Positives = 28/56 (50%), Gaps = 1/56 (1%)

Query: 3   RLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKD-GKFRKFGFIGFKSEEEAQK 57
           ++ V  L     ++  +  F  FG + DC++K   + G+ R FGFI FK     +K
Sbjct: 71  KMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKDAASVEK 126


>gi|7661952 squamous cell carcinoma antigen recognized by T cells 3
           [Homo sapiens]
          Length = 963

 Score = 75.5 bits (184), Expect = 2e-13
 Identities = 80/316 (25%), Positives = 136/316 (43%), Gaps = 57/316 (18%)

Query: 190 EEEASLEPKAAVQKELSDMDYLKSKMVKAGSSSSSEEEESEDEAVHCDEGSEAEEEDSSA 249
           E+EA+L  +   + E       + K +K        E+   DE    + G + EE+ S  
Sbjct: 585 EKEAALVQQEEEKAEQRKRARAEKKALKKKKKIRGPEKRGADEDDEKEWGDDEEEQPSKR 644

Query: 250 TPVLQERDSKGAGQEQGM-----PAGKKRPPEARAETEKPANQKE---------PTTCH- 294
             V  E     AG+ Q +     PAGK     A  + E P+ QKE         P   H 
Sbjct: 645 RRV--ENSIPAAGETQNVEVAAGPAGKC----AAVDVEPPSKQKEKAASLKRDMPKVLHD 698

Query: 295 ------TVKLRGAPFNVTEKNVMEFLAPL-----KPVAIRIVRNAHGNKTGYIFVDFSNE 343
                 TV +   P+++ E +    L PL     + V IR + +  G+  GY +V+F  E
Sbjct: 699 SSKDSITVFVSNLPYSMQEPDTK--LRPLFEACGEVVQIRPIFSNRGDFRGYCYVEFKEE 756

Query: 344 EEVKQALKCNREYMGGRYIEVF----REKNVPTTKGAPKNTTKSWQGRILGENEEEEDLA 399
           +   QAL+ +R+ + GR + V     + KN P  K    +T+                  
Sbjct: 757 KSALQALEMDRKSVEGRPMFVSPCVDKSKN-PDFKVFRYSTS-----------------L 798

Query: 400 ESGRLFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKA 459
           E  +LF+  LP++ T+E+LE++   +G + +L   + +   KPKG A++ +     A +A
Sbjct: 799 EKHKLFISGLPFSCTKEELEEICKAHGTVKDLRL-VTNRAGKPKGLAYVEYENESQASQA 857

Query: 460 YSEVDGQVFQGRMLHV 475
             ++DG   +  ++ V
Sbjct: 858 VMKMDGMTIKENIIKV 873



 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 35/108 (32%), Positives = 52/108 (48%), Gaps = 13/108 (12%)

Query: 726 SLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPE 785
           SL    LFI  L F  T+E+L+E+    GTVK   +    N+AG     G  +VEY    
Sbjct: 797 SLEKHKLFISGLPFSCTKEELEEICKAHGTVKDLRL--VTNRAG--KPKGLAYVEYENES 852

Query: 786 QAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSK 833
           QA +A+ ++ G         + I E   K A++   +++VP K  T K
Sbjct: 853 QASQAVMKMDG---------MTIKENIIKVAISNPPQRKVPEKPETRK 891



 Score = 36.2 bits (82), Expect = 0.15
 Identities = 22/64 (34%), Positives = 33/64 (51%), Gaps = 2/64 (3%)

Query: 4   LIVKNLPNGMKEE--RFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKH 61
           + V NLP  M+E   + R LF A G +      F+  G FR + ++ FK E+ A +A + 
Sbjct: 706 VFVSNLPYSMQEPDTKLRPLFEACGEVVQIRPIFSNRGDFRGYCYVEFKEEKSALQALEM 765

Query: 62  FNKS 65
             KS
Sbjct: 766 DRKS 769



 Score = 33.1 bits (74), Expect = 1.3
 Identities = 34/157 (21%), Positives = 61/157 (38%), Gaps = 19/157 (12%)

Query: 3   RLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKHF 62
           +L +  LP    +E   ++  A GT+ D  L   + GK +   ++ +++E +A +A    
Sbjct: 802 KLFISGLPFSCTKEELEEICKAHGTVKDLRLVTNRAGKPKGLAYVEYENESQASQAVMKM 861

Query: 63  NKSFIDTSRITVEFCKSFGDPAKPRAWSKHAQKPSQPKQPPKDSTTPEIKKDEKKKKVAG 122
           +   I  + I V    +  +P +     K  +KP   K P      P+      K +   
Sbjct: 862 DGMTIKENIIKV----AISNPPQ----RKVPEKPETRKAPGGPMLLPQTYGARGKGR--- 910

Query: 123 QLEKLKEDTEFQEFLSVHQRRAQAATWANDGLDAEPS 159
                   T+        QR + AA  A +G  A P+
Sbjct: 911 --------TQLSLLPRALQRPSAAAPQAENGPAAAPA 939


>gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo
           sapiens]
          Length = 614

 Score = 73.9 bits (180), Expect = 7e-13
 Identities = 88/415 (21%), Positives = 166/415 (40%), Gaps = 64/415 (15%)

Query: 404 LFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEV 463
           L+V +L    TE  L + FS  GP+  +    D  T++  G+A+I F  P  A +A   +
Sbjct: 13  LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDTM 72

Query: 464 DGQVFQGRMLHVLPSTIKKEASEDASALGSSSYKKKKEAQDKANSASSHNWNTLFMGPNA 523
           + ++ +G+ + ++ S  +++     S +G+   K  +++ D  N A    ++T     N 
Sbjct: 73  NFEMLKGQPIRIMWS--QRDPGLRKSGVGNIFIKNLEDSID--NKALYDTFSTF---GNI 125

Query: 524 VADAIAQKYNATKSQVFDHETKGSVAVRVALGETQLVQEVRRFLIDNGVSLDSFSQAAAE 583
           ++  +A   + ++   F H      A +       ++   R+  + +  S          
Sbjct: 126 LSCKVACDEHGSRGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGHFKSRREREAELGA 185

Query: 584 RSK--TVILVKNLPAGTLAAQLQETFGHFGSL--GRVLLPEGGIT---AIVEFLEPLEAR 636
           R+   T I VKNLP       LQ+ F  FG +   +V+    G +     V F +  EA+
Sbjct: 186 RALEFTNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDNSGHSRCFGFVNFEKHEEAQ 245

Query: 637 KAFRHLAYSKFHHVPLYLEWAPVGVFSSTAPQKKKLQDTPSEPMEKDPAEPETVPDGETP 696
           KA  H+   +     LY   A                                       
Sbjct: 246 KAVVHMNGKEVSGRLLYAGRA--------------------------------------- 266

Query: 697 EDENPTEEGADNSSAKMEEEEEEEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTV 756
                 ++  +  +      E+ +++      G  L++KNL+    ++KL++ FS  G +
Sbjct: 267 ------QKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKNLDDSIDDDKLRKEFSPYGVI 320

Query: 757 KSCSISKKKNKAGVLLSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKLEVRISER 811
            S  +  +        S GFGFV +  PE+A KA+ ++ G +V    L V +++R
Sbjct: 321 TSAKVMTEGGH-----SKGFGFVCFSSPEEATKAVTEMNGRIVGTKPLYVALAQR 370



 Score = 72.4 bits (176), Expect = 2e-12
 Identities = 53/179 (29%), Positives = 90/179 (50%), Gaps = 12/179 (6%)

Query: 717 EEEEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGF 776
           E E E    +L    +++KNL  D  E+ L+++FS+ G  K  S+   ++ +G   S  F
Sbjct: 178 EREAELGARALEFTNIYVKNLPVDVDEQGLQDLFSQFG--KMLSVKVMRDNSGH--SRCF 233

Query: 777 GFVEYRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVTLAR-----KKQVPRKQTT 831
           GFV + K E+AQKA+  + G  V G  L    +++  +    L R     K+   R+   
Sbjct: 234 GFVNFEKHEEAQKAVVHMNGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQG 293

Query: 832 SKILVRNIPFQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRA 890
             + V+N+       ++R+ FS +G + +    K MT  G  +GFGFV F + ++A +A
Sbjct: 294 VNLYVKNLDDSIDDDKLRKEFSPYGVITSA---KVMTEGGHSKGFGFVCFSSPEEATKA 349



 Score = 71.6 bits (174), Expect = 3e-12
 Identities = 47/160 (29%), Positives = 84/160 (52%), Gaps = 14/160 (8%)

Query: 732 LFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPEQAQKAL 791
           +FIKNL      + L + FS  G + SC ++  ++      S GFGFV +   E AQ+A+
Sbjct: 101 IFIKNLEDSIDNKALYDTFSTFGNILSCKVACDEHG-----SRGFGFVHFETHEAAQQAI 155

Query: 792 KQLQGHVVDGHKLEV-RISERATKPAVTLARKKQVPRKQTTSKILVRNIPFQAHSREIRE 850
             + G +++  K+ V     R  + A   AR  +       + I V+N+P     + +++
Sbjct: 156 NTMNGMLLNDRKVFVGHFKSRREREAELGARALEF------TNIYVKNLPVDVDEQGLQD 209

Query: 851 LFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRA 890
           LFS FG++ +V++ +    +G  R FGFV+F   ++A++A
Sbjct: 210 LFSQFGKMLSVKVMR--DNSGHSRCFGFVNFEKHEEAQKA 247



 Score = 68.2 bits (165), Expect = 4e-11
 Identities = 43/167 (25%), Positives = 83/167 (49%), Gaps = 17/167 (10%)

Query: 728 PGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPEQA 787
           P  +L++ +L+ D TE  L E FS  G + S  + +         S+G+ ++ +++P  A
Sbjct: 9   PLASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRD---VATRRSLGYAYINFQQPADA 65

Query: 788 QKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIPFQAHSRE 847
           ++AL  +   ++ G  + +  S+R   P +         RK     I ++N+     ++ 
Sbjct: 66  ERALDTMNFEMLKGQPIRIMWSQR--DPGL---------RKSGVGNIFIKNLEDSIDNKA 114

Query: 848 IRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNAL 894
           + + FSTFG + + ++     G+   RGFGFV F T + A++A N +
Sbjct: 115 LYDTFSTFGNILSCKVACDEHGS---RGFGFVHFETHEAAQQAINTM 158



 Score = 60.5 bits (145), Expect = 7e-09
 Identities = 46/191 (24%), Positives = 93/191 (48%), Gaps = 13/191 (6%)

Query: 296 VKLRGAPFNVTEKNVMEFLAPL-KPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQAL-KCN 353
           + ++  P +V E+ + +  +   K ++++++R+  G+   + FV+F   EE ++A+   N
Sbjct: 193 IYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDNSGHSRCFGFVNFEKHEEAQKAVVHMN 252

Query: 354 REYMGGRYIEVFR-EKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYT 412
            + + GR +   R +K V       +   +  Q R+           +   L+V+NL  +
Sbjct: 253 GKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRY--------QGVNLYVKNLDDS 304

Query: 413 STEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRM 472
             ++ L K FS YG ++      +      KGF F+ F  PE A KA +E++G++   + 
Sbjct: 305 IDDDKLRKEFSPYGVITSAKVMTEG--GHSKGFGFVCFSSPEEATKAVTEMNGRIVGTKP 362

Query: 473 LHVLPSTIKKE 483
           L+V  +  K+E
Sbjct: 363 LYVALAQRKEE 373



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 40/159 (25%), Positives = 70/159 (44%), Gaps = 26/159 (16%)

Query: 320 VAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCNREYMGGRYIEVFREKNVPTTKGAPKN 379
           ++ ++  + HG++ G+ FV F   E  +QA+                     T  G   N
Sbjct: 126 LSCKVACDEHGSR-GFGFVHFETHEAAQQAIN--------------------TMNGMLLN 164

Query: 380 TTKSWQGRILGENEEEEDLA----ESGRLFVRNLPYTSTEEDLEKLFSKYGPLSELHYPI 435
             K + G      E E +L     E   ++V+NLP    E+ L+ LFS++G +  +    
Sbjct: 165 DRKVFVGHFKSRREREAELGARALEFTNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMR 224

Query: 436 DSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLH 474
           D+ +   + F F+ F   E A KA   ++G+   GR+L+
Sbjct: 225 DN-SGHSRCFGFVNFEKHEEAQKAVVHMNGKEVSGRLLY 262



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 24/62 (38%), Positives = 34/62 (54%)

Query: 2   SRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKH 61
           + + VKNLP  + E+  + LF+ FG +    +     G  R FGF+ F+  EEAQKA  H
Sbjct: 191 TNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDNSGHSRCFGFVNFEKHEEAQKAVVH 250

Query: 62  FN 63
            N
Sbjct: 251 MN 252



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 24/71 (33%), Positives = 39/71 (54%), Gaps = 1/71 (1%)

Query: 4   LIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKHFN 63
           L VKNL + + +++ R+ F+ +G +T   +  T+ G  + FGF+ F S EEA KA    N
Sbjct: 296 LYVKNLDDSIDDDKLRKEFSPYGVITSAKV-MTEGGHSKGFGFVCFSSPEEATKAVTEMN 354

Query: 64  KSFIDTSRITV 74
              + T  + V
Sbjct: 355 GRIVGTKPLYV 365



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 46/193 (23%), Positives = 83/193 (43%), Gaps = 30/193 (15%)

Query: 304 NVTEKNVMEFLAPLKPV-AIRIVRNAHGNKT-GYIFVDFSNEEEVKQALKC-NREYMGGR 360
           +VTE  + E  +P  P+ +IR+ R+    ++ GY +++F    + ++AL   N E + G+
Sbjct: 21  DVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDTMNFEMLKGQ 80

Query: 361 YIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEK 420
            I +   +  P   G  K+                      G +F++NL  +   + L  
Sbjct: 81  PIRIMWSQRDP---GLRKSGV--------------------GNIFIKNLEDSIDNKALYD 117

Query: 421 LFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHV--LPS 478
            FS +G +       D      +GF F+ F   E A +A + ++G +   R + V    S
Sbjct: 118 TFSTFGNILSCKVACDE--HGSRGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGHFKS 175

Query: 479 TIKKEASEDASAL 491
             ++EA   A AL
Sbjct: 176 RREREAELGARAL 188



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 21/79 (26%), Positives = 39/79 (49%), Gaps = 1/79 (1%)

Query: 1   MSRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQK 60
           +  + +KNL + +  +     F+ FG +  C +   + G  R FGF+ F++ E AQ+A  
Sbjct: 98  VGNIFIKNLEDSIDNKALYDTFSTFGNILSCKVACDEHGS-RGFGFVHFETHEAAQQAIN 156

Query: 61  HFNKSFIDTSRITVEFCKS 79
             N   ++  ++ V   KS
Sbjct: 157 TMNGMLLNDRKVFVGHFKS 175


>gi|74099697 heterogeneous nuclear ribonucleoprotein H2 [Homo
           sapiens]
          Length = 449

 Score = 73.9 bits (180), Expect = 7e-13
 Identities = 55/169 (32%), Positives = 83/169 (49%), Gaps = 18/169 (10%)

Query: 296 VKLRGAPFNVTEKNVMEFLAPLK----PVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALK 351
           VK+RG P++ +   VM F +  K       IR +    G  +G  FV+  +EEEVK ALK
Sbjct: 13  VKVRGLPWSCSADEVMRFFSDCKIQNGTSGIRFIYTREGRPSGEAFVELESEEEVKLALK 72

Query: 352 CNREYMGGRYIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPY 411
            +RE MG RY+EVF+  +V             W  +  G N    D A  G + +R LP+
Sbjct: 73  KDRETMGHRYVEVFKSNSV----------EMDWVLKHTGPN--SPDTANDGFVRLRGLPF 120

Query: 412 TSTEEDLEKLFSKYGPL-SELHYPIDSLTKKPKGFAFITFMFPEHAVKA 459
             ++E++ + FS    + + +  P+D    +  G AF+ F   E A KA
Sbjct: 121 GCSKEEIVQFFSGLEIVPNGMTLPVD-FQGRSTGEAFVQFASQEIAEKA 168



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 29/88 (32%), Positives = 46/88 (52%)

Query: 289 EPTTCHTVKLRGAPFNVTEKNVMEFLAPLKPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQ 348
           + TT H V +RG P+  TE ++  F +PL P+ + I     G  TG   V+F+  E+   
Sbjct: 284 QSTTGHCVHMRGLPYRATENDIYNFFSPLNPMRVHIEIGPDGRVTGEADVEFATHEDAVA 343

Query: 349 ALKCNREYMGGRYIEVFREKNVPTTKGA 376
           A+  ++  M  RY+E+F      T+ GA
Sbjct: 344 AMAKDKANMQHRYVELFLNSTAGTSGGA 371



 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 26/73 (35%), Positives = 48/73 (65%), Gaps = 2/73 (2%)

Query: 296 VKLRGAPFNVTEKNVMEFLAPLK--PVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCN 353
           V+LRG PF  +++ +++F + L+  P  + +  +  G  TG  FV F+++E  ++ALK +
Sbjct: 113 VRLRGLPFGCSKEEIVQFFSGLEIVPNGMTLPVDFQGRSTGEAFVQFASQEIAEKALKKH 172

Query: 354 REYMGGRYIEVFR 366
           +E +G RYIE+F+
Sbjct: 173 KERIGHRYIEIFK 185


>gi|9624998 heterogeneous nuclear ribonucleoprotein H2 [Homo
           sapiens]
          Length = 449

 Score = 73.9 bits (180), Expect = 7e-13
 Identities = 55/169 (32%), Positives = 83/169 (49%), Gaps = 18/169 (10%)

Query: 296 VKLRGAPFNVTEKNVMEFLAPLK----PVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALK 351
           VK+RG P++ +   VM F +  K       IR +    G  +G  FV+  +EEEVK ALK
Sbjct: 13  VKVRGLPWSCSADEVMRFFSDCKIQNGTSGIRFIYTREGRPSGEAFVELESEEEVKLALK 72

Query: 352 CNREYMGGRYIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPY 411
            +RE MG RY+EVF+  +V             W  +  G N    D A  G + +R LP+
Sbjct: 73  KDRETMGHRYVEVFKSNSV----------EMDWVLKHTGPN--SPDTANDGFVRLRGLPF 120

Query: 412 TSTEEDLEKLFSKYGPL-SELHYPIDSLTKKPKGFAFITFMFPEHAVKA 459
             ++E++ + FS    + + +  P+D    +  G AF+ F   E A KA
Sbjct: 121 GCSKEEIVQFFSGLEIVPNGMTLPVD-FQGRSTGEAFVQFASQEIAEKA 168



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 29/88 (32%), Positives = 46/88 (52%)

Query: 289 EPTTCHTVKLRGAPFNVTEKNVMEFLAPLKPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQ 348
           + TT H V +RG P+  TE ++  F +PL P+ + I     G  TG   V+F+  E+   
Sbjct: 284 QSTTGHCVHMRGLPYRATENDIYNFFSPLNPMRVHIEIGPDGRVTGEADVEFATHEDAVA 343

Query: 349 ALKCNREYMGGRYIEVFREKNVPTTKGA 376
           A+  ++  M  RY+E+F      T+ GA
Sbjct: 344 AMAKDKANMQHRYVELFLNSTAGTSGGA 371



 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 26/73 (35%), Positives = 48/73 (65%), Gaps = 2/73 (2%)

Query: 296 VKLRGAPFNVTEKNVMEFLAPLK--PVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCN 353
           V+LRG PF  +++ +++F + L+  P  + +  +  G  TG  FV F+++E  ++ALK +
Sbjct: 113 VRLRGLPFGCSKEEIVQFFSGLEIVPNGMTLPVDFQGRSTGEAFVQFASQEIAEKALKKH 172

Query: 354 REYMGGRYIEVFR 366
           +E +G RYIE+F+
Sbjct: 173 KERIGHRYIEIFK 185


>gi|77695912 TIA-1 related protein isoform 2 [Homo sapiens]
          Length = 392

 Score = 73.2 bits (178), Expect = 1e-12
 Identities = 59/197 (29%), Positives = 99/197 (50%), Gaps = 33/197 (16%)

Query: 731 TLFIKNLNFDTTEEKLKEVFSKVGTVKSCS-ISKKKNKAGVLLSMGFG-----------F 778
           TL++ NL+ D TE  + ++FS++G  KSC  I+++ +   V  S+GF            F
Sbjct: 10  TLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQPDSRRVNSSVGFSVLQHTSNDPYCF 69

Query: 779 VEYRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSK---IL 835
           VE+ +   A  AL  + G  + G +++V     AT P+          +K+ TS    + 
Sbjct: 70  VEFYEHRDAAAALAAMNGRKILGKEVKV---NWATTPS---------SQKKDTSNHFHVF 117

Query: 836 VRNIPFQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNALC 895
           V ++  +  + +I+  F+ FG++   R+ K M  TG  +G+GFV F  K DA+   NA+ 
Sbjct: 118 VGDLSPEITTEDIKSAFAPFGKISDARVVKDM-ATGKSKGYGFVSFYNKLDAE---NAIV 173

Query: 896 H--STHLYGRRLVLEWA 910
           H     L GR++   WA
Sbjct: 174 HMGGQWLGGRQIRTNWA 190



 Score = 53.9 bits (128), Expect = 7e-07
 Identities = 47/197 (23%), Positives = 95/197 (48%), Gaps = 19/197 (9%)

Query: 284 PANQKEPTTCHTVKLRG--APFNVTEKNVMEFLAPLKPVA-IRIVRN-AHGNKTGYIFVD 339
           P++QK+ T+ H     G  +P  +T +++    AP   ++  R+V++ A G   GY FV 
Sbjct: 103 PSSQKKDTSNHFHVFVGDLSP-EITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVS 161

Query: 340 FSNEEEVKQAL-KCNREYMGGRYIEV-FREKNVPTTKGAPKNTTKSWQGRILGENEEEED 397
           F N+ + + A+     +++GGR I   +  +  P  K   +N TK    ++  E+   + 
Sbjct: 162 FYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQENNTK----QLRFEDVVNQS 217

Query: 398 LAESGRLFVRNLPYTSTEEDLEKLFSKYGPLSELH-YPIDSLTKKPKGFAFITFMFPEHA 456
             ++  ++   +    T++ + + FS +G + E+  +P        KG++F+ F   E A
Sbjct: 218 SPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFP-------EKGYSFVRFSTHESA 270

Query: 457 VKAYSEVDGQVFQGRML 473
             A   V+G   +G ++
Sbjct: 271 AHAIVSVNGTTIEGHVV 287



 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 44/185 (23%), Positives = 72/185 (38%), Gaps = 24/185 (12%)

Query: 329 HGNKTGYIFVDFSNEEEVKQALKCNREYMGGRYIEVFREKNVPTTKGAPKNTTKSWQGRI 388
           H +   Y FV+F    +   AL      M GR I               K    +W    
Sbjct: 61  HTSNDPYCFVEFYEHRDAAAALAA----MNGRKI-------------LGKEVKVNWATT- 102

Query: 389 LGENEEEEDLAESGRLFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFI 448
              + +++D +    +FV +L    T ED++  F+ +G +S+     D  T K KG+ F+
Sbjct: 103 --PSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFV 160

Query: 449 TFMFPEHAVKAYSEVDGQVFQGRMLHVLPSTIKKEASEDASALGSSSYKKKKEAQDKANS 508
           +F     A  A   + GQ   GR +    +T K  A +        +  K+   +D  N 
Sbjct: 161 SFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKST----QENNTKQLRFEDVVNQ 216

Query: 509 ASSHN 513
           +S  N
Sbjct: 217 SSPKN 221


>gi|5031753 heterogeneous nuclear ribonucleoprotein H1 [Homo
           sapiens]
          Length = 449

 Score = 72.8 bits (177), Expect = 1e-12
 Identities = 54/169 (31%), Positives = 82/169 (48%), Gaps = 18/169 (10%)

Query: 296 VKLRGAPFNVTEKNVMEFLAPLK----PVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALK 351
           VK+RG P++ +   V  F +  K       IR +    G  +G  FV+  +E+EVK ALK
Sbjct: 13  VKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTREGRPSGEAFVELESEDEVKLALK 72

Query: 352 CNREYMGGRYIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPY 411
            +RE MG RY+EVF+  NV             W  +  G N    D A  G + +R LP+
Sbjct: 73  KDRETMGHRYVEVFKSNNV----------EMDWVLKHTGPN--SPDTANDGFVRLRGLPF 120

Query: 412 TSTEEDLEKLFSKYGPL-SELHYPIDSLTKKPKGFAFITFMFPEHAVKA 459
             ++E++ + FS    + + +  P+D    +  G AF+ F   E A KA
Sbjct: 121 GCSKEEIVQFFSGLEIVPNGITLPVD-FQGRSTGEAFVQFASQEIAEKA 168



 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 29/88 (32%), Positives = 45/88 (51%)

Query: 289 EPTTCHTVKLRGAPFNVTEKNVMEFLAPLKPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQ 348
           + TT H V +RG P+  TE ++  F +PL PV + I     G  TG   V+F+  E+   
Sbjct: 284 QSTTGHCVHMRGLPYRATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEDAVA 343

Query: 349 ALKCNREYMGGRYIEVFREKNVPTTKGA 376
           A+  ++  M  RY+E+F       + GA
Sbjct: 344 AMSKDKANMQHRYVELFLNSTAGASGGA 371



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 27/73 (36%), Positives = 48/73 (65%), Gaps = 2/73 (2%)

Query: 296 VKLRGAPFNVTEKNVMEFLAPLK--PVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCN 353
           V+LRG PF  +++ +++F + L+  P  I +  +  G  TG  FV F+++E  ++ALK +
Sbjct: 113 VRLRGLPFGCSKEEIVQFFSGLEIVPNGITLPVDFQGRSTGEAFVQFASQEIAEKALKKH 172

Query: 354 REYMGGRYIEVFR 366
           +E +G RYIE+F+
Sbjct: 173 KERIGHRYIEIFK 185


>gi|14110407 heterogeneous nuclear ribonucleoprotein D-like [Homo
           sapiens]
          Length = 420

 Score = 72.8 bits (177), Expect = 1e-12
 Identities = 57/235 (24%), Positives = 102/235 (43%), Gaps = 28/235 (11%)

Query: 662 FSSTAPQKKKLQDTPSEPMEKDPAEPETVPDGETPEDENPTEEGADNSSAKMEEEEEEEE 721
           F S++ Q+       +    + P    +V   +  E  N  EE A+ S     + ++++ 
Sbjct: 90  FKSSSIQRSAAAAAATRTARQHPPADSSVTMEDMNEYSN-IEEFAEGSKINASKNQQDDG 148

Query: 722 EEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEY 781
           +         +FI  L++DT+++ L E  S+ G V  C+I   K       S GFGFV +
Sbjct: 149 K---------MFIGGLSWDTSKKDLTEYLSRFGEVVDCTI---KTDPVTGRSRGFGFVLF 196

Query: 782 RKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIPF 841
           +      K L +L+ H +DG  ++ +             R K +  K+   K+ V  +  
Sbjct: 197 KDAASVDKVL-ELKEHKLDGKLIDPK-------------RAKALKGKEPPKKVFVGGLSP 242

Query: 842 QAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNALCH 896
                +I+E F  FGE++ + LP   T T   RGF F+ +  ++  K+   +  H
Sbjct: 243 DTSEEQIKEYFGAFGEIENIELPMD-TKTNERRGFCFITYTDEEPVKKLLESRYH 296



 Score = 47.4 bits (111), Expect = 7e-05
 Identities = 38/174 (21%), Positives = 73/174 (41%), Gaps = 27/174 (15%)

Query: 300 GAPFNVTEKNVMEFLAPLKPVAIRIVRN--AHGNKTGYIFVDFSNEEEVKQALKCNREYM 357
           G  ++ ++K++ E+L+    V    ++     G   G+ FV F +   V + L+     +
Sbjct: 154 GLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAASVDKVLELKEHKL 213

Query: 358 GGRYIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEED 417
            G+ I+  R K +   K  PK                        ++FV  L   ++EE 
Sbjct: 214 DGKLIDPKRAKALKG-KEPPK------------------------KVFVGGLSPDTSEEQ 248

Query: 418 LEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGR 471
           +++ F  +G +  +  P+D+ T + +GF FIT+   E   K       Q+  G+
Sbjct: 249 IKEYFGAFGEIENIELPMDTKTNERRGFCFITYTDEEPVKKLLESRYHQIGSGK 302



 Score = 37.0 bits (84), Expect = 0.089
 Identities = 15/66 (22%), Positives = 38/66 (57%), Gaps = 3/66 (4%)

Query: 385 QGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKG 444
           +G  +  ++ ++D    G++F+  L + ++++DL +  S++G + +     D +T + +G
Sbjct: 134 EGSKINASKNQQD---DGKMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRG 190

Query: 445 FAFITF 450
           F F+ F
Sbjct: 191 FGFVLF 196



 Score = 31.2 bits (69), Expect = 4.9
 Identities = 18/56 (32%), Positives = 28/56 (50%), Gaps = 1/56 (1%)

Query: 3   RLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKF-TKDGKFRKFGFIGFKSEEEAQK 57
           ++ V  L     EE+ ++ F AFG + +  L   TK  + R F FI +  EE  +K
Sbjct: 234 KVFVGGLSPDTSEEQIKEYFGAFGEIENIELPMDTKTNERRGFCFITYTDEEPVKK 289


>gi|188219591 TIA1 protein isoform 2 [Homo sapiens]
          Length = 386

 Score = 72.4 bits (176), Expect = 2e-12
 Identities = 52/189 (27%), Positives = 94/189 (49%), Gaps = 10/189 (5%)

Query: 724 EESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRK 783
           E+ +P  TL++ NL+ D TE  + ++FS++G  K+C +    + AG   +  + FVE+ +
Sbjct: 2   EDEMPK-TLYVGNLSRDVTEALILQLFSQIGPCKNCKMI--MDTAG---NDPYCFVEFHE 55

Query: 784 PEQAQKALKQLQGHVVDGHKLEVR--ISERATKPAVTLARKKQVPRKQTTSKILVRNIPF 841
              A  AL  + G  + G +++V    +  + K   + +      R Q    + V ++  
Sbjct: 56  HRHAAAALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSP 115

Query: 842 QAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNALCHSTHLY 901
           +  + +I+  F+ FG +   R+ K M  TG  +G+GFV F  K DA+ A   +     L 
Sbjct: 116 EITTEDIKAAFAPFGRISDARVVKDM-ATGKSKGYGFVSFFNKWDAENAIQQM-GGQWLG 173

Query: 902 GRRLVLEWA 910
           GR++   WA
Sbjct: 174 GRQIRTNWA 182



 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 54/221 (24%), Positives = 99/221 (44%), Gaps = 22/221 (9%)

Query: 304 NVTEKNVMEFLAPLKPVA-IRIVRNAHGNKTGYIFVDFSNEEEVKQALKC-NREYMGGRY 361
           +VTE  +++  + + P    +++ +  GN   Y FV+F        AL   N   + G+ 
Sbjct: 17  DVTEALILQLFSQIGPCKNCKMIMDTAGNDP-YCFVEFHEHRHAAAALAAMNGRKIMGKE 75

Query: 362 IEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEKL 421
           ++V    N  TT  + K  T S    ++     ++       +FV +L    T ED++  
Sbjct: 76  VKV----NWATTPSSQKKDTSS--STVVSTQRSQDHF----HVFVGDLSPEITTEDIKAA 125

Query: 422 FSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHVLPSTIK 481
           F+ +G +S+     D  T K KG+ F++F     A  A  ++ GQ   GR +    +T K
Sbjct: 126 FAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRK 185

Query: 482 KEASEDASALGSSSYKK--KKEAQDKANSASSHNWNTLFMG 520
             A +       S+Y+   K+ + D+  + SS +  T++ G
Sbjct: 186 PPAPK-------STYESNTKQLSYDEVVNQSSPSNCTVYCG 219



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 41/172 (23%), Positives = 81/172 (47%), Gaps = 12/172 (6%)

Query: 305 VTEKNVMEFLAPLKPVA-IRIVRN-AHGNKTGYIFVDFSNEEEVKQALK-CNREYMGGRY 361
           +T +++    AP   ++  R+V++ A G   GY FV F N+ + + A++    +++GGR 
Sbjct: 117 ITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQ 176

Query: 362 IEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEKL 421
           I        P    APK+T +S   ++  +    +    +  ++   +    TE+ + + 
Sbjct: 177 IRTNWATRKPP---APKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQT 233

Query: 422 FSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRML 473
           FS +G + E+    D      KG++F+ F   E A  A   V+G   +G ++
Sbjct: 234 FSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIVSVNGTTIEGHVV 279



 Score = 38.5 bits (88), Expect = 0.030
 Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 5/101 (4%)

Query: 404 LFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEV 463
           L+V NL    TE  + +LFS+ GP       +D+    P  + F+ F    HA  A + +
Sbjct: 9   LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP--YCFVEFHEHRHAAAALAAM 66

Query: 464 DGQVFQGRMLHVLPSTIKKEASEDASALGSSSYKKKKEAQD 504
           +G+   G+ + V  +T      +D S   SS+    + +QD
Sbjct: 67  NGRKIMGKEVKVNWATTPSSQKKDTS---SSTVVSTQRSQD 104



 Score = 37.4 bits (85), Expect = 0.068
 Identities = 19/84 (22%), Positives = 36/84 (42%), Gaps = 9/84 (10%)

Query: 719 EEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGF 778
           +E   + S   CT++   +    TE+ +++ FS  G +    +   K         G+ F
Sbjct: 203 DEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDK---------GYSF 253

Query: 779 VEYRKPEQAQKALKQLQGHVVDGH 802
           V +   E A  A+  + G  ++GH
Sbjct: 254 VRFNSHESAAHAIVSVNGTTIEGH 277


>gi|148470406 heterogeneous nuclear ribonucleoprotein F [Homo
           sapiens]
          Length = 415

 Score = 71.6 bits (174), Expect = 3e-12
 Identities = 54/169 (31%), Positives = 83/169 (49%), Gaps = 18/169 (10%)

Query: 296 VKLRGAPFNVTEKNVMEFLAPLK----PVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALK 351
           VKLRG P++ + ++V  FL+          +  +    G ++G  FV+  +E++VK ALK
Sbjct: 13  VKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKMALK 72

Query: 352 CNREYMGGRYIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPY 411
            +RE MG RYIEVF+             T   W  +  G N    D A  G + +R LP+
Sbjct: 73  KDRESMGHRYIEVFKS----------HRTEMDWVLKHSGPN--SADSANDGFVRLRGLPF 120

Query: 412 TSTEEDLEKLFSKYGPL-SELHYPIDSLTKKPKGFAFITFMFPEHAVKA 459
             T+E++ + FS    + + +  P+D    K  G AF+ F   E A KA
Sbjct: 121 GCTKEEIVQFFSGLEIVPNGITLPVDP-EGKITGEAFVQFASQELAEKA 168



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 32/88 (36%), Positives = 45/88 (51%)

Query: 289 EPTTCHTVKLRGAPFNVTEKNVMEFLAPLKPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQ 348
           + TT H V +RG P+  TE ++  F +PL PV + I     G  TG   V+F+  EE   
Sbjct: 284 QSTTGHCVHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEEAVA 343

Query: 349 ALKCNREYMGGRYIEVFREKNVPTTKGA 376
           A+  +R  M  RYIE+F       + GA
Sbjct: 344 AMSKDRANMQHRYIELFLNSTTGASNGA 371



 Score = 53.9 bits (128), Expect = 7e-07
 Identities = 28/73 (38%), Positives = 47/73 (64%), Gaps = 2/73 (2%)

Query: 296 VKLRGAPFNVTEKNVMEFLAPLK--PVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCN 353
           V+LRG PF  T++ +++F + L+  P  I +  +  G  TG  FV F+++E  ++AL  +
Sbjct: 113 VRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKH 172

Query: 354 REYMGGRYIEVFR 366
           +E +G RYIEVF+
Sbjct: 173 KERIGHRYIEVFK 185



 Score = 32.3 bits (72), Expect = 2.2
 Identities = 21/83 (25%), Positives = 40/83 (48%), Gaps = 5/83 (6%)

Query: 6   VKNLPNGMKEERFRQLFAAFGTLTD-CSLKFTKDGKFRKFGFIGFKSEEEAQKA----QK 60
           ++ LP G  +E   Q F+    + +  +L    +GK     F+ F S+E A+KA    ++
Sbjct: 115 LRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKHKE 174

Query: 61  HFNKSFIDTSRITVEFCKSFGDP 83
                +I+  + + E  +S+ DP
Sbjct: 175 RIGHRYIEVFKSSQEEVRSYSDP 197


>gi|148470404 heterogeneous nuclear ribonucleoprotein F [Homo
           sapiens]
          Length = 415

 Score = 71.6 bits (174), Expect = 3e-12
 Identities = 54/169 (31%), Positives = 83/169 (49%), Gaps = 18/169 (10%)

Query: 296 VKLRGAPFNVTEKNVMEFLAPLK----PVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALK 351
           VKLRG P++ + ++V  FL+          +  +    G ++G  FV+  +E++VK ALK
Sbjct: 13  VKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKMALK 72

Query: 352 CNREYMGGRYIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPY 411
            +RE MG RYIEVF+             T   W  +  G N    D A  G + +R LP+
Sbjct: 73  KDRESMGHRYIEVFKS----------HRTEMDWVLKHSGPN--SADSANDGFVRLRGLPF 120

Query: 412 TSTEEDLEKLFSKYGPL-SELHYPIDSLTKKPKGFAFITFMFPEHAVKA 459
             T+E++ + FS    + + +  P+D    K  G AF+ F   E A KA
Sbjct: 121 GCTKEEIVQFFSGLEIVPNGITLPVDP-EGKITGEAFVQFASQELAEKA 168



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 32/88 (36%), Positives = 45/88 (51%)

Query: 289 EPTTCHTVKLRGAPFNVTEKNVMEFLAPLKPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQ 348
           + TT H V +RG P+  TE ++  F +PL PV + I     G  TG   V+F+  EE   
Sbjct: 284 QSTTGHCVHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEEAVA 343

Query: 349 ALKCNREYMGGRYIEVFREKNVPTTKGA 376
           A+  +R  M  RYIE+F       + GA
Sbjct: 344 AMSKDRANMQHRYIELFLNSTTGASNGA 371



 Score = 53.9 bits (128), Expect = 7e-07
 Identities = 28/73 (38%), Positives = 47/73 (64%), Gaps = 2/73 (2%)

Query: 296 VKLRGAPFNVTEKNVMEFLAPLK--PVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCN 353
           V+LRG PF  T++ +++F + L+  P  I +  +  G  TG  FV F+++E  ++AL  +
Sbjct: 113 VRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKH 172

Query: 354 REYMGGRYIEVFR 366
           +E +G RYIEVF+
Sbjct: 173 KERIGHRYIEVFK 185



 Score = 32.3 bits (72), Expect = 2.2
 Identities = 21/83 (25%), Positives = 40/83 (48%), Gaps = 5/83 (6%)

Query: 6   VKNLPNGMKEERFRQLFAAFGTLTD-CSLKFTKDGKFRKFGFIGFKSEEEAQKA----QK 60
           ++ LP G  +E   Q F+    + +  +L    +GK     F+ F S+E A+KA    ++
Sbjct: 115 LRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKHKE 174

Query: 61  HFNKSFIDTSRITVEFCKSFGDP 83
                +I+  + + E  +S+ DP
Sbjct: 175 RIGHRYIEVFKSSQEEVRSYSDP 197


>gi|148470402 heterogeneous nuclear ribonucleoprotein F [Homo
           sapiens]
          Length = 415

 Score = 71.6 bits (174), Expect = 3e-12
 Identities = 54/169 (31%), Positives = 83/169 (49%), Gaps = 18/169 (10%)

Query: 296 VKLRGAPFNVTEKNVMEFLAPLK----PVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALK 351
           VKLRG P++ + ++V  FL+          +  +    G ++G  FV+  +E++VK ALK
Sbjct: 13  VKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKMALK 72

Query: 352 CNREYMGGRYIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPY 411
            +RE MG RYIEVF+             T   W  +  G N    D A  G + +R LP+
Sbjct: 73  KDRESMGHRYIEVFKS----------HRTEMDWVLKHSGPN--SADSANDGFVRLRGLPF 120

Query: 412 TSTEEDLEKLFSKYGPL-SELHYPIDSLTKKPKGFAFITFMFPEHAVKA 459
             T+E++ + FS    + + +  P+D    K  G AF+ F   E A KA
Sbjct: 121 GCTKEEIVQFFSGLEIVPNGITLPVDP-EGKITGEAFVQFASQELAEKA 168



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 32/88 (36%), Positives = 45/88 (51%)

Query: 289 EPTTCHTVKLRGAPFNVTEKNVMEFLAPLKPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQ 348
           + TT H V +RG P+  TE ++  F +PL PV + I     G  TG   V+F+  EE   
Sbjct: 284 QSTTGHCVHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEEAVA 343

Query: 349 ALKCNREYMGGRYIEVFREKNVPTTKGA 376
           A+  +R  M  RYIE+F       + GA
Sbjct: 344 AMSKDRANMQHRYIELFLNSTTGASNGA 371



 Score = 53.9 bits (128), Expect = 7e-07
 Identities = 28/73 (38%), Positives = 47/73 (64%), Gaps = 2/73 (2%)

Query: 296 VKLRGAPFNVTEKNVMEFLAPLK--PVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCN 353
           V+LRG PF  T++ +++F + L+  P  I +  +  G  TG  FV F+++E  ++AL  +
Sbjct: 113 VRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKH 172

Query: 354 REYMGGRYIEVFR 366
           +E +G RYIEVF+
Sbjct: 173 KERIGHRYIEVFK 185



 Score = 32.3 bits (72), Expect = 2.2
 Identities = 21/83 (25%), Positives = 40/83 (48%), Gaps = 5/83 (6%)

Query: 6   VKNLPNGMKEERFRQLFAAFGTLTD-CSLKFTKDGKFRKFGFIGFKSEEEAQKA----QK 60
           ++ LP G  +E   Q F+    + +  +L    +GK     F+ F S+E A+KA    ++
Sbjct: 115 LRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKHKE 174

Query: 61  HFNKSFIDTSRITVEFCKSFGDP 83
                +I+  + + E  +S+ DP
Sbjct: 175 RIGHRYIEVFKSSQEEVRSYSDP 197


>gi|148470400 heterogeneous nuclear ribonucleoprotein F [Homo
           sapiens]
          Length = 415

 Score = 71.6 bits (174), Expect = 3e-12
 Identities = 54/169 (31%), Positives = 83/169 (49%), Gaps = 18/169 (10%)

Query: 296 VKLRGAPFNVTEKNVMEFLAPLK----PVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALK 351
           VKLRG P++ + ++V  FL+          +  +    G ++G  FV+  +E++VK ALK
Sbjct: 13  VKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKMALK 72

Query: 352 CNREYMGGRYIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPY 411
            +RE MG RYIEVF+             T   W  +  G N    D A  G + +R LP+
Sbjct: 73  KDRESMGHRYIEVFKS----------HRTEMDWVLKHSGPN--SADSANDGFVRLRGLPF 120

Query: 412 TSTEEDLEKLFSKYGPL-SELHYPIDSLTKKPKGFAFITFMFPEHAVKA 459
             T+E++ + FS    + + +  P+D    K  G AF+ F   E A KA
Sbjct: 121 GCTKEEIVQFFSGLEIVPNGITLPVDP-EGKITGEAFVQFASQELAEKA 168



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 32/88 (36%), Positives = 45/88 (51%)

Query: 289 EPTTCHTVKLRGAPFNVTEKNVMEFLAPLKPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQ 348
           + TT H V +RG P+  TE ++  F +PL PV + I     G  TG   V+F+  EE   
Sbjct: 284 QSTTGHCVHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEEAVA 343

Query: 349 ALKCNREYMGGRYIEVFREKNVPTTKGA 376
           A+  +R  M  RYIE+F       + GA
Sbjct: 344 AMSKDRANMQHRYIELFLNSTTGASNGA 371



 Score = 53.9 bits (128), Expect = 7e-07
 Identities = 28/73 (38%), Positives = 47/73 (64%), Gaps = 2/73 (2%)

Query: 296 VKLRGAPFNVTEKNVMEFLAPLK--PVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCN 353
           V+LRG PF  T++ +++F + L+  P  I +  +  G  TG  FV F+++E  ++AL  +
Sbjct: 113 VRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKH 172

Query: 354 REYMGGRYIEVFR 366
           +E +G RYIEVF+
Sbjct: 173 KERIGHRYIEVFK 185



 Score = 32.3 bits (72), Expect = 2.2
 Identities = 21/83 (25%), Positives = 40/83 (48%), Gaps = 5/83 (6%)

Query: 6   VKNLPNGMKEERFRQLFAAFGTLTD-CSLKFTKDGKFRKFGFIGFKSEEEAQKA----QK 60
           ++ LP G  +E   Q F+    + +  +L    +GK     F+ F S+E A+KA    ++
Sbjct: 115 LRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKHKE 174

Query: 61  HFNKSFIDTSRITVEFCKSFGDP 83
                +I+  + + E  +S+ DP
Sbjct: 175 RIGHRYIEVFKSSQEEVRSYSDP 197


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.128    0.359 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,279,282
Number of Sequences: 37866
Number of extensions: 2050945
Number of successful extensions: 30353
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 509
Number of HSP's successfully gapped in prelim test: 694
Number of HSP's that attempted gapping in prelim test: 14966
Number of HSP's gapped (non-prelim): 10334
length of query: 960
length of database: 18,247,518
effective HSP length: 112
effective length of query: 848
effective length of database: 14,006,526
effective search space: 11877534048
effective search space used: 11877534048
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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