Guide to the Human Genome
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Search of human proteins with 223633919

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|223633919 hypothetical protein LOC285550 [Homo sapiens]
         (657 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|223633919 hypothetical protein LOC285550 [Homo sapiens]           1315   0.0  
gi|21495178 hypothetical protein LOC221786 [Homo sapiens]             879   0.0  
gi|46195755 SCAN domain containing 3 [Homo sapiens]                   412   e-115
gi|115511046 zinc finger protein 258 [Homo sapiens]                   410   e-114
gi|219521826 zinc finger, BED-type containing 5 [Homo sapiens]        347   2e-95
gi|49574210 zinc finger, BED-type containing 5 [Homo sapiens]         347   2e-95
gi|28916698 transposon-derived Buster3 transposase-like [Homo sa...   319   6e-87
gi|51241788 GTF2I repeat domain containing 2B [Homo sapiens]          148   2e-35
gi|48762700 GTF2I repeat domain containing 2 [Homo sapiens]           146   5e-35
gi|7662294 EPM2A interacting protein 1 [Homo sapiens]                 110   4e-24
gi|55741653 hypothetical protein LOC57691 [Homo sapiens]               41   0.004
gi|113205089 zinc finger, MYM domain containing 1 [Homo sapiens]       40   0.005
gi|149773449 zinc finger protein 862 [Homo sapiens]                    39   0.012
gi|21361633 leucine rich repeat containing 40 [Homo sapiens]           36   0.098
gi|33188431 tetratricopeptide repeat protein isoform 3 [Homo sap...    35   0.29 
gi|33188429 tetratricopeptide repeat protein isoform 1 [Homo sap...    35   0.29 
gi|33188427 tetratricopeptide repeat protein isoform 2 [Homo sap...    35   0.29 
gi|239752520 PREDICTED: similar to Rap guanine nucleotide exchan...    34   0.37 
gi|7657261 Rap guanine nucleotide exchange factor 2 [Homo sapiens]     34   0.37 
gi|87299628 biorientation of chromosomes in cell division 1-like...    33   0.83 
gi|119395734 breast cancer 2, early onset [Homo sapiens]               32   1.9  
gi|54633319 PDZ domain-containing guanine nucleotide exchange fa...    31   3.2  
gi|23503283 TBC1 domain family, member 21 [Homo sapiens]               31   3.2  
gi|66773040 phosphatidic acid phosphatase type 2 domain containi...    31   3.2  
gi|156627573 zinc finger protein 836 [Homo sapiens]                    31   4.1  
gi|62899047 RAD50 interactor 1 [Homo sapiens]                          30   5.4  
gi|21450836 zinc finger with UFM1-specific peptidase domain [Hom...    30   5.4  
gi|226246537 zinc finger protein 407 isoform 3 [Homo sapiens]          30   7.1  
gi|226246535 zinc finger protein 407 isoform 2 [Homo sapiens]          30   7.1  
gi|134133288 zinc finger protein 407 isoform 1 [Homo sapiens]          30   7.1  

>gi|223633919 hypothetical protein LOC285550 [Homo sapiens]
          Length = 657

 Score = 1315 bits (3403), Expect = 0.0
 Identities = 657/657 (100%), Positives = 657/657 (100%)

Query: 1   MDHFFIKRKRNSEVKYTEACSSSSVESGIVNSDNIEKNTDSNLQTSTSFEPHFKKKKVSA 60
           MDHFFIKRKRNSEVKYTEACSSSSVESGIVNSDNIEKNTDSNLQTSTSFEPHFKKKKVSA
Sbjct: 1   MDHFFIKRKRNSEVKYTEACSSSSVESGIVNSDNIEKNTDSNLQTSTSFEPHFKKKKVSA 60

Query: 61  RRYNEDYLKYGFIKCEKPFENDRPQCVICNNILANESLKPSKLKRHLETQHAELIDKPLE 120
           RRYNEDYLKYGFIKCEKPFENDRPQCVICNNILANESLKPSKLKRHLETQHAELIDKPLE
Sbjct: 61  RRYNEDYLKYGFIKCEKPFENDRPQCVICNNILANESLKPSKLKRHLETQHAELIDKPLE 120

Query: 121 YFQRKKKDIKLSTQFLSCSTAVSEKALLSSYLVAYRVAKEKIANTAAEKIILPACLDMVR 180
           YFQRKKKDIKLSTQFLSCSTAVSEKALLSSYLVAYRVAKEKIANTAAEKIILPACLDMVR
Sbjct: 121 YFQRKKKDIKLSTQFLSCSTAVSEKALLSSYLVAYRVAKEKIANTAAEKIILPACLDMVR 180

Query: 181 TIFDDKSADKLKTIPNDNTVSLRICTIAEHLETMLITRLQSGIDFAIQLDESTDIGSCTT 240
           TIFDDKSADKLKTIPNDNTVSLRICTIAEHLETMLITRLQSGIDFAIQLDESTDIGSCTT
Sbjct: 181 TIFDDKSADKLKTIPNDNTVSLRICTIAEHLETMLITRLQSGIDFAIQLDESTDIGSCTT 240

Query: 241 LLVYVRYAWQDDFLEDFLCFLNLTSHLSGLDIFTELERRIVGQYKLNWKNCKGITSDGTA 300
           LLVYVRYAWQDDFLEDFLCFLNLTSHLSGLDIFTELERRIVGQYKLNWKNCKGITSDGTA
Sbjct: 241 LLVYVRYAWQDDFLEDFLCFLNLTSHLSGLDIFTELERRIVGQYKLNWKNCKGITSDGTA 300

Query: 301 TMTGKHSRVIKKLLEVTNNGAVWNHCFIHREGLASREIPQNLMEVLKNAVKVVNFIKGSS 360
           TMTGKHSRVIKKLLEVTNNGAVWNHCFIHREGLASREIPQNLMEVLKNAVKVVNFIKGSS
Sbjct: 301 TMTGKHSRVIKKLLEVTNNGAVWNHCFIHREGLASREIPQNLMEVLKNAVKVVNFIKGSS 360

Query: 361 LNSRLLETFCSEIGTNHTHLLYHTKIRWLSQGKILSRVYELRNEIHFFLIEKKSHLASIF 420
           LNSRLLETFCSEIGTNHTHLLYHTKIRWLSQGKILSRVYELRNEIHFFLIEKKSHLASIF
Sbjct: 361 LNSRLLETFCSEIGTNHTHLLYHTKIRWLSQGKILSRVYELRNEIHFFLIEKKSHLASIF 420

Query: 421 EDDTWVTKLAYLTDIFSILNELSLKLQGKNSDVFQHVERIQGFRKTLLLWQVRLKSNRPS 480
           EDDTWVTKLAYLTDIFSILNELSLKLQGKNSDVFQHVERIQGFRKTLLLWQVRLKSNRPS
Sbjct: 421 EDDTWVTKLAYLTDIFSILNELSLKLQGKNSDVFQHVERIQGFRKTLLLWQVRLKSNRPS 480

Query: 481 YYMFPRFLQHIEENIINENILKEIKLEILLHLTSLSQTFNHFFPEEKFETLRENSWVKDP 540
           YYMFPRFLQHIEENIINENILKEIKLEILLHLTSLSQTFNHFFPEEKFETLRENSWVKDP
Sbjct: 481 YYMFPRFLQHIEENIINENILKEIKLEILLHLTSLSQTFNHFFPEEKFETLRENSWVKDP 540

Query: 541 FAFRHPESIIELNLVPEEENELLQLSSSYTLKNDYETLSLSAFWMKVKEDFPLLSRKSVL 600
           FAFRHPESIIELNLVPEEENELLQLSSSYTLKNDYETLSLSAFWMKVKEDFPLLSRKSVL
Sbjct: 541 FAFRHPESIIELNLVPEEENELLQLSSSYTLKNDYETLSLSAFWMKVKEDFPLLSRKSVL 600

Query: 601 LLLPFTTTSLCELGFSILTQLKTKERNGLNCAAVMRVALSSCVPDWNELMNRQAHPS 657
           LLLPFTTTSLCELGFSILTQLKTKERNGLNCAAVMRVALSSCVPDWNELMNRQAHPS
Sbjct: 601 LLLPFTTTSLCELGFSILTQLKTKERNGLNCAAVMRVALSSCVPDWNELMNRQAHPS 657


>gi|21495178 hypothetical protein LOC221786 [Homo sapiens]
          Length = 573

 Score =  879 bits (2271), Expect = 0.0
 Identities = 429/539 (79%), Positives = 491/539 (91%), Gaps = 1/539 (0%)

Query: 120 EYFQRKKKDIKLSTQFLSCSTAVSEKALLSSYLVAYRVAKEKIANTAAEKIILPACLDMV 179
           ++FQ+++  ++ S Q LS ST ++E+ALLSSYLVAYRVAKEK+A+TAAEKIILPAC+DMV
Sbjct: 34  DHFQKERNKVESSPQVLSRSTTMNERALLSSYLVAYRVAKEKMAHTAAEKIILPACMDMV 93

Query: 180 RTIFDDKSADKLKTIP-NDNTVSLRICTIAEHLETMLITRLQSGIDFAIQLDESTDIGSC 238
           RTIFDDKSADKL+TIP +DNT+S RICTIA+HLE MLITRLQSGIDFAIQLDESTDI SC
Sbjct: 94  RTIFDDKSADKLRTIPLSDNTISRRICTIAKHLEAMLITRLQSGIDFAIQLDESTDIASC 153

Query: 239 TTLLVYVRYAWQDDFLEDFLCFLNLTSHLSGLDIFTELERRIVGQYKLNWKNCKGITSDG 298
            TLLVYVRY WQDDF+ED LC LNL SH++GLD+FTELE  ++GQYKLNWK+CKGI+SDG
Sbjct: 154 PTLLVYVRYVWQDDFVEDLLCCLNLNSHITGLDLFTELENCLLGQYKLNWKHCKGISSDG 213

Query: 299 TATMTGKHSRVIKKLLEVTNNGAVWNHCFIHREGLASREIPQNLMEVLKNAVKVVNFIKG 358
           TA MTGKHSR+ +KLLE T+N AVWNHCFIHRE L S+EI  +LM+VLKNAVK VNFIKG
Sbjct: 214 TANMTGKHSRLTEKLLEATHNNAVWNHCFIHREALVSKEISPSLMDVLKNAVKTVNFIKG 273

Query: 359 SSLNSRLLETFCSEIGTNHTHLLYHTKIRWLSQGKILSRVYELRNEIHFFLIEKKSHLAS 418
           SSLNSRLLE FCSEIG NHTHLL+HT++RWLSQGK+LSRVYELRNEI+ FL+EK+SHLA+
Sbjct: 274 SSLNSRLLEIFCSEIGVNHTHLLFHTEVRWLSQGKVLSRVYELRNEIYIFLVEKQSHLAN 333

Query: 419 IFEDDTWVTKLAYLTDIFSILNELSLKLQGKNSDVFQHVERIQGFRKTLLLWQVRLKSNR 478
           IFEDD WVTKLAYL+DIF ILNELSLK+QGKN+D+FQ++E I GF+KTLLLWQ RLKSNR
Sbjct: 334 IFEDDIWVTKLAYLSDIFGILNELSLKMQGKNNDIFQYLEHILGFQKTLLLWQARLKSNR 393

Query: 479 PSYYMFPRFLQHIEENIINENILKEIKLEILLHLTSLSQTFNHFFPEEKFETLRENSWVK 538
           PSYYMFP  LQHIEENIINE+ LKEIKLEILLHLTSLSQTFN++FPEEKFE+L+EN W+K
Sbjct: 394 PSYYMFPTLLQHIEENIINEDCLKEIKLEILLHLTSLSQTFNYYFPEEKFESLKENIWMK 453

Query: 539 DPFAFRHPESIIELNLVPEEENELLQLSSSYTLKNDYETLSLSAFWMKVKEDFPLLSRKS 598
           DPFAF++PESIIELNL PEEENELLQLSSS+TLKN Y+ LSLSAFW+K+K+DFPLLSRKS
Sbjct: 454 DPFAFQNPESIIELNLEPEEENELLQLSSSFTLKNYYKILSLSAFWIKIKDDFPLLSRKS 513

Query: 599 VLLLLPFTTTSLCELGFSILTQLKTKERNGLNCAAVMRVALSSCVPDWNELMNRQAHPS 657
           +LLLLPFTTT LCELGFSILT+LKTK+RN LN A  MRVALSSCVPDW ELMNRQAHPS
Sbjct: 514 ILLLLPFTTTYLCELGFSILTRLKTKKRNRLNSAPDMRVALSSCVPDWKELMNRQAHPS 572


>gi|46195755 SCAN domain containing 3 [Homo sapiens]
          Length = 1325

 Score =  412 bits (1059), Expect = e-115
 Identities = 237/616 (38%), Positives = 372/616 (60%), Gaps = 16/616 (2%)

Query: 48   SFEPHFKKKKVSA---RRYNEDYLKYGFIKCEKPFENDRPQCVICNNILANESLKPSKLK 104
            S+    K K+V A   R+Y+  Y+++GF+      E  +PQC+IC ++LANE++KPSKLK
Sbjct: 719  SYPEEGKTKRVHASFTRKYDPSYIEFGFVAVIDG-EVLKPQCIICGDVLANEAMKPSKLK 777

Query: 105  RHLETQHAELIDKPLEYFQRKKKDIKLSTQFLSCSTAVSEKALLSSYLVAYRVAKEKIAN 164
            RHL ++H E+  +P E+F+RK  ++K   + +   + ++  AL +SY VA  VAK K   
Sbjct: 778  RHLYSKHKEISSQPKEFFERKSSELKSQPKQVFNVSHINISALRASYKVALPVAKSKTPY 837

Query: 165  TAAEKIILPACLDMVRTIFDDKSADKLKTIPNDN-TVSLRICTIAEHLETMLITRLQSGI 223
            T AE ++     ++   +  + +A K+  +P  N T++ RI  +A  +E  LI +++   
Sbjct: 838  TIAETLVKDCIKEVCLEMLGESAAKKVAQVPLSNDTIARRIQELANDMEDQLIEQIKLAK 897

Query: 224  DFAIQLDESTDIGSCTTLLVYVRYAWQDDFLEDFLCFLNLTSHLSGLDIFTELERRIVGQ 283
             F++QLDE  DI +   LLVYVR+   DD  E+F    +L ++ +  +++  ++  IV +
Sbjct: 898  YFSLQLDECRDIANMIILLVYVRFEHDDDIKEEFFFSASLPTNTTSSELYEAVKNYIVNK 957

Query: 284  YKLNWKNCKGITSDGTATMTGKHSRVIKKLLEVTNNGAVWNHCFIHREGLASREIPQNLM 343
              L +K C G+ SDG A+MTGKHS V+ ++ E+        HCFIHRE LA ++I   L 
Sbjct: 958  CGLEFKFCVGVCSDGAASMTGKHSEVVTQIKELAPECKT-THCFIHRESLAMKKISAELN 1016

Query: 344  EVLKNAVKVVNFIKGSSLNSRLLETFCSEIGTNHTHLLYHTKIRWLSQGKILSRVYELRN 403
             VL + VK+VN+IK +SLNSRL    C  +  +H  LL H +IRWLS+GK+LSR++E+RN
Sbjct: 1017 SVLNDIVKIVNYIKSNSLNSRLFSLLCDNMEADHKQLLLHAEIRWLSRGKVLSRMFEIRN 1076

Query: 404  EIHFFLIEKKSHLASIFEDDTWVTKLAYLTDIFSILNELSLKLQGKNSDVFQHVERIQGF 463
            E+  FL  KK   + +F+D  W  +LAYL+DIFSI N+L+  +QGKN+  F   ++++G 
Sbjct: 1077 ELLVFLQGKKPMWSQLFKDVNWTARLAYLSDIFSIFNDLNASMQGKNATYFSMADKVEGQ 1136

Query: 464  RKTLLLWQVRLKSNRPSYYMFPRFLQHIEENIINENILKEIKLEILLHLTSLSQTFNHFF 523
            ++ L  W+ R+ ++   Y MF      I E + N+  +  ++  I  HLT+L + F  +F
Sbjct: 1137 KQKLEAWKNRISTD--CYDMFHNLTTIINE-VGNDLDIAHLRKVISEHLTNLLECFEFYF 1193

Query: 524  PEEKFETLRENSWVKDPFAFRHPESIIELNLVPEEENELLQLSSSYTLKNDYE-TLSLSA 582
            P ++   +  N W+++PF      S   LNL    +++LL+L++   LK  +E T SL +
Sbjct: 1194 PSKEDPRI-GNLWIQNPFL----SSKDNLNLTVTLQDKLLKLATDEGLKISFENTASLPS 1248

Query: 583  FWMKVKEDFPLLSRKSVLLLLPFTTTSLCELGFSILTQLKTKERNGLNCAAVMRVALSSC 642
            FW+K K D+P L+  ++ LLL F +T LCE GFS L+ +KTK RN LN    +RVALSS 
Sbjct: 1249 FWIKAKNDYPELAEIALKLLLLFPSTYLCETGFSTLSVIKTKHRNSLNIHYPLRVALSSI 1308

Query: 643  VPDWNELMN-RQAHPS 657
             P  ++L + +QAH S
Sbjct: 1309 QPRLDKLTSKKQAHLS 1324


>gi|115511046 zinc finger protein 258 [Homo sapiens]
          Length = 1325

 Score =  410 bits (1053), Expect = e-114
 Identities = 225/608 (37%), Positives = 368/608 (60%), Gaps = 19/608 (3%)

Query: 51   PHFKKKKVSA-RRYNEDYLKYGFIKCEKPFEND-RPQCVICNNILANESLKPSKLKRHLE 108
            P  KKK++   + Y+ +YLK GFI C    E+  RPQCVIC  IL++E++KP+ L  HL+
Sbjct: 731  PPSKKKRLGFFQTYDTEYLKVGFIICPGSKESSPRPQCVICGEILSSENMKPANLSHHLK 790

Query: 109  TQHAELIDKPLEYFQRKKKDIKLSTQFLSCSTAVSEKALLSSYLVAYRVAKEKIANTAAE 168
            T+H+EL +KP+++F++K  +++     L     V +  + +SYL+A++ A  K   + AE
Sbjct: 791  TKHSELENKPVDFFEQKSLEMECQNSSLKKCLLVEKSLVKASYLIAFQTAASKKPFSIAE 850

Query: 169  KIILPACLDMVRTIFDDKSADKLKTIPNDN-TVSLRICTIAEHLETMLITRLQSGIDFAI 227
            ++I P  ++M   +    + DK+KTIP  N T+  RI  ++  +E  LI +++    FA+
Sbjct: 851  ELIKPYLVEMCSEVLGSSAGDKMKTIPLSNVTIQHRIDELSADIEDQLIQKVRESKWFAL 910

Query: 228  QLDESTDIGSCTTLLVYVRYAWQD--DFLEDFLCFLNLTSHLSGLDIFTELERRIVGQYK 285
            Q+DES++I + T LL Y+R+   D  D  E+ L  + + + ++G +IF EL  + +    
Sbjct: 911  QIDESSEISNITLLLCYIRFIDYDCRDVKEELLFCIEMPTQITGFEIF-ELINKYIDSKS 969

Query: 286  LNWKNCKGITSDGTATMTGKHSRVIKKLLEVTNNGAVWNHCFIHREGLASREIPQNLMEV 345
            LNWK+C G+ +DG A+MTG++S +  K+ EV  N A + HCFIHRE L + ++   L ++
Sbjct: 970  LNWKHCVGLCTDGAASMTGRYSGLKAKIQEVAMNTAAFTHCFIHRERLVAEKLSPCLHKI 1029

Query: 346  LKNAVKVVNFIKGSSLNSRLLETFCSEIGTNHTHLLYHTKIRWLSQGKILSRVYELRNEI 405
            L  + ++++FIK ++LNSR+L   C E+G+ H  L  H ++RW+S+G++L R++ELR+EI
Sbjct: 1030 LLQSAQILSFIKSNALNSRMLTILCEEMGSEHVSLPLHAEVRWISRGRMLKRLFELRHEI 1089

Query: 406  HFFLIEKKSHLASIFEDDTWVTKLAYLTDIFSILNELSLKLQGKNSDVFQHVERIQGFRK 465
              FL +K S LA  F D+ WV KLAYL+DIFS++NEL+L LQG  +  F    +I  F++
Sbjct: 1090 EIFLSQKHSDLAKYFHDEEWVGKLAYLSDIFSLINELNLSLQGTLTTFFNLCNKIDVFKR 1149

Query: 466  TLLLWQVRLKSNRPSYYMFPRFLQHIEENIINENILKEIKLEILLHLTSLSQTFNHFFPE 525
             L +W  R + N   Y MFP F +    + +N   + +I   I  HL  LSQ F+  FP 
Sbjct: 1150 KLKMWLKRTQEN--DYDMFPSFSEFSNSSGLN---MTDITRIIFEHLEGLSQVFSDCFPP 1204

Query: 526  EKFETLRENSWVKDPFAFRHPESIIELNLVPEEENELLQLSSSYTLKNDYETLSLSAFWM 585
            E+ +    N W+  PF   H  +    NL   EE +L +LSS   L+  ++++S++ FW+
Sbjct: 1205 EQ-DLRSGNLWIIHPF-MNHQNN----NLTDFEEEKLTELSSDLGLQALFKSVSVTQFWI 1258

Query: 586  KVKEDFPLLSRKSVLLLLPFTTTSLCELGFSILTQLKTKERNGLNCAAVMRVALSSCVPD 645
              K  +P L  +++  LLPF+T  LC+  FS LT+  +K++N L     +R+A++S +P 
Sbjct: 1259 NAKTSYPELHERAMKFLLPFSTVYLCDAAFSALTE--SKQKNLLGSGPALRLAVTSLIPR 1316

Query: 646  WNELMNRQ 653
              +L+  +
Sbjct: 1317 IEKLVKEK 1324


>gi|219521826 zinc finger, BED-type containing 5 [Homo sapiens]
          Length = 693

 Score =  347 bits (891), Expect = 2e-95
 Identities = 209/605 (34%), Positives = 340/605 (56%), Gaps = 28/605 (4%)

Query: 56  KKVSARRYNEDYLKYGFIKCEKPFEN-DRP--QCVICNNILANESLKPSKLKRHLETQHA 112
           KK   R+Y+E YL +GF      F N D P  QCV+C  IL+N SL PSKL+RHLET+HA
Sbjct: 103 KKPKRRKYDESYLSFGFTY----FGNRDAPHAQCVLCKKILSNSSLAPSKLRRHLETKHA 158

Query: 113 ELIDKPLEYFQR---KKKDIKLSTQFLSCSTAVSEKALLSSYLVAYRVAKEKIANTAAEK 169
              DK + +F++     ++ K  T  +  +   +E A  +SY V+Y +A    A+T  E 
Sbjct: 159 AYKDKDISFFKQHLDSPENNKPPTPKIVNTD--NESATEASYNVSYHIALSGEAHTIGEL 216

Query: 170 IILPACLDMVRTIFDDKSADKLKTIPNDN-TVSLRICTIAEHLETMLITRLQSGIDFAIQ 228
           +I P   D+V  +FD++ + K+  +   N TV+ RI  +A  +E  L+ RL+    F++Q
Sbjct: 217 LIKPCAKDVVMRMFDEQYSKKIDAVQLSNSTVARRIKDLAADIEEELVCRLKICDGFSLQ 276

Query: 229 LDESTDIGSCTTLLVYVRYAWQDDFLEDFLCFLNLTSHLSGLDIFTELERRIVGQYKLNW 288
           LDES D+     LLV+VRY +     ED L   +L S+ +G +IF  +    + ++++ W
Sbjct: 277 LDESADVSGLAVLLVFVRYRFNKSIEEDLLLCESLQSNATGEEIFNCINS-FMQKHEIEW 335

Query: 289 KNCKGITSDGTATMTGKHSRVIKKLLEVTNNGAVWNHCFIHREGLASREIPQNLMEVLKN 348
           + C  + SD +  + GK +  +  L++     +  +HC ++R  LA + +P +L  VL  
Sbjct: 336 EKCVDVCSDASRAVDGKIAEAVT-LIKYVAPESTSSHCLLYRHALAVKIMPTSLKNVLDQ 394

Query: 349 AVKVVNFIKGSSLNSRLLETFCSEIGTNHTHLLYHTKIRWLSQGKILSRVYELRNEIHFF 408
           AV+++N+IK     SRLL+  C E+G  HT LL +T++RWLS+GK+L R++ELR E+  F
Sbjct: 395 AVQIINYIKARPHQSRLLKILCEEMGAQHTALLLNTEVRWLSRGKVLVRLFELRRELLVF 454

Query: 409 LIEKKSHLASIFEDDTWVTKLAYLTDIFSILNELSLKLQGKNSDVFQHVERIQGFRKTLL 468
           + +    L+    + +W+ +LAYL DIF+ LNE++L +QGKN  VF   +++    + L 
Sbjct: 455 M-DSAFRLSDCLTNSSWLLRLAYLADIFTKLNEVNLSMQGKNVTVFTVFDKMSSLLRKLE 513

Query: 469 LWQVRLKSNRPSYYMFPRFLQHIEENIINENILKEIKLEILLHLTSLSQTFNHFFPEEKF 528
            W   ++    ++  FP     + E  IN  + K+I   I+ HL  L  T   +FP    
Sbjct: 514 FWASSVEEE--NFDCFPTLSDFLTE--INSTVDKDICSAIVQHLRGLRATLLKYFP---- 565

Query: 529 ETLRENSWVKDPFAFRHPESIIELNLVPEEENELLQLSSSYTLKNDYETLSLSAFWMKVK 588
            T   N+WV++PF      ++   +LV  +   L+ L+S   +K ++  LSL+ FW  + 
Sbjct: 566 VTNDNNAWVRNPFTV----TVKPASLVARDYESLIDLTSDSQVKQNFSELSLNDFWSSLI 621

Query: 589 EDFPLLSRKSVLLLLPFTTTSLCELGFSILTQLKTKERNGLNCAAVMRVALSSCVPDWNE 648
           +++P ++R++V +LLPF T  LCE GFS     KTK R  L+ A  MR+ LS+  P+   
Sbjct: 622 QEYPSIARRAVRVLLPFATMHLCETGFSYYAATKTKYRKRLDAAPHMRIRLSNITPNIKR 681

Query: 649 LMNRQ 653
           + +++
Sbjct: 682 ICDKK 686


>gi|49574210 zinc finger, BED-type containing 5 [Homo sapiens]
          Length = 693

 Score =  347 bits (891), Expect = 2e-95
 Identities = 209/605 (34%), Positives = 340/605 (56%), Gaps = 28/605 (4%)

Query: 56  KKVSARRYNEDYLKYGFIKCEKPFEN-DRP--QCVICNNILANESLKPSKLKRHLETQHA 112
           KK   R+Y+E YL +GF      F N D P  QCV+C  IL+N SL PSKL+RHLET+HA
Sbjct: 103 KKPKRRKYDESYLSFGFTY----FGNRDAPHAQCVLCKKILSNSSLAPSKLRRHLETKHA 158

Query: 113 ELIDKPLEYFQR---KKKDIKLSTQFLSCSTAVSEKALLSSYLVAYRVAKEKIANTAAEK 169
              DK + +F++     ++ K  T  +  +   +E A  +SY V+Y +A    A+T  E 
Sbjct: 159 AYKDKDISFFKQHLDSPENNKPPTPKIVNTD--NESATEASYNVSYHIALSGEAHTIGEL 216

Query: 170 IILPACLDMVRTIFDDKSADKLKTIPNDN-TVSLRICTIAEHLETMLITRLQSGIDFAIQ 228
           +I P   D+V  +FD++ + K+  +   N TV+ RI  +A  +E  L+ RL+    F++Q
Sbjct: 217 LIKPCAKDVVMRMFDEQYSKKIDAVQLSNSTVARRIKDLAADIEEELVCRLKICDGFSLQ 276

Query: 229 LDESTDIGSCTTLLVYVRYAWQDDFLEDFLCFLNLTSHLSGLDIFTELERRIVGQYKLNW 288
           LDES D+     LLV+VRY +     ED L   +L S+ +G +IF  +    + ++++ W
Sbjct: 277 LDESADVSGLAVLLVFVRYRFNKSIEEDLLLCESLQSNATGEEIFNCINS-FMQKHEIEW 335

Query: 289 KNCKGITSDGTATMTGKHSRVIKKLLEVTNNGAVWNHCFIHREGLASREIPQNLMEVLKN 348
           + C  + SD +  + GK +  +  L++     +  +HC ++R  LA + +P +L  VL  
Sbjct: 336 EKCVDVCSDASRAVDGKIAEAVT-LIKYVAPESTSSHCLLYRHALAVKIMPTSLKNVLDQ 394

Query: 349 AVKVVNFIKGSSLNSRLLETFCSEIGTNHTHLLYHTKIRWLSQGKILSRVYELRNEIHFF 408
           AV+++N+IK     SRLL+  C E+G  HT LL +T++RWLS+GK+L R++ELR E+  F
Sbjct: 395 AVQIINYIKARPHQSRLLKILCEEMGAQHTALLLNTEVRWLSRGKVLVRLFELRRELLVF 454

Query: 409 LIEKKSHLASIFEDDTWVTKLAYLTDIFSILNELSLKLQGKNSDVFQHVERIQGFRKTLL 468
           + +    L+    + +W+ +LAYL DIF+ LNE++L +QGKN  VF   +++    + L 
Sbjct: 455 M-DSAFRLSDCLTNSSWLLRLAYLADIFTKLNEVNLSMQGKNVTVFTVFDKMSSLLRKLE 513

Query: 469 LWQVRLKSNRPSYYMFPRFLQHIEENIINENILKEIKLEILLHLTSLSQTFNHFFPEEKF 528
            W   ++    ++  FP     + E  IN  + K+I   I+ HL  L  T   +FP    
Sbjct: 514 FWASSVEEE--NFDCFPTLSDFLTE--INSTVDKDICSAIVQHLRGLRATLLKYFP---- 565

Query: 529 ETLRENSWVKDPFAFRHPESIIELNLVPEEENELLQLSSSYTLKNDYETLSLSAFWMKVK 588
            T   N+WV++PF      ++   +LV  +   L+ L+S   +K ++  LSL+ FW  + 
Sbjct: 566 VTNDNNAWVRNPFTV----TVKPASLVARDYESLIDLTSDSQVKQNFSELSLNDFWSSLI 621

Query: 589 EDFPLLSRKSVLLLLPFTTTSLCELGFSILTQLKTKERNGLNCAAVMRVALSSCVPDWNE 648
           +++P ++R++V +LLPF T  LCE GFS     KTK R  L+ A  MR+ LS+  P+   
Sbjct: 622 QEYPSIARRAVRVLLPFATMHLCETGFSYYAATKTKYRKRLDAAPHMRIRLSNITPNIKR 681

Query: 649 LMNRQ 653
           + +++
Sbjct: 682 ICDKK 686


>gi|28916698 transposon-derived Buster3 transposase-like [Homo
           sapiens]
          Length = 594

 Score =  319 bits (817), Expect = 6e-87
 Identities = 194/600 (32%), Positives = 326/600 (54%), Gaps = 25/600 (4%)

Query: 61  RRYNEDYLKYGFIKCEKPFENDRPQCVICNNILANESLKPSKLKRHLETQHAELIDKPLE 120
           R++++DY++Y F    +     RPQCV+CN++ +N  L+PSKL  H   QH  +    L 
Sbjct: 5   RKWDDDYVRYWFTCTTEVDGTQRPQCVLCNSVFSNADLRPSKLSDHFNRQHGGVAGHDLN 64

Query: 121 YFQRKKKDIKLSTQFLSCSTAVSEKALL-SSYLVAYRVAKEKIANTAAEKIILPACLDMV 179
             +        S    +   A  E  LL +SY  AY  AKEK  +T AEK++ P  L++ 
Sbjct: 65  SLKHMPAPSDQSETLKAFGVASHEDTLLQASYQFAYLCAKEKNPHTVAEKLVKPCALEIA 124

Query: 180 RTIFDDKSADKLKTIP-NDNTVSLRICTIAEHLETMLITRLQ-SGIDFAIQLDESTDIGS 237
           + +    +  KL+ +P +D+ +  RI  +++ +   ++  ++ S +   IQL E+TD+  
Sbjct: 125 QIVLGPDAQKKLQQVPLSDDVIHSRIDEMSQDILQQVLEDIKASPLKVGIQLAETTDMDD 184

Query: 238 CTTLLVYVRYAWQDDFLEDFLCFLNLTSHLSGLDIFTELERRIVGQYKLNWKNCKGITSD 297
           C+ L+ +VRY  + + +E+FL    L   + G+D+F  L R    ++K+    C  + +D
Sbjct: 185 CSQLMAFVRYIKEREIVEEFLFCEPLQLSMKGIDVFN-LFRDFFLKHKIALDVCGSVCTD 243

Query: 298 GTATMTGKHSRVIKKLLEVTNNGAVWNHCFIHREGLASREIPQNLMEVLKNAVKVVNFIK 357
           G ++M G++S  +  + +   +  V  HC ++   L  + +P  L + L   V+V+NFIK
Sbjct: 244 GASSMLGENSEFVAYVKKEIPHIVV-THCLLNPHALVIKTLPTKLRDALFTVVRVINFIK 302

Query: 358 GSSLNSRLLETFCSEIGTNHTHLLYHTKIRWLSQGKILSRVYELRNEIHFFLIEKKSHLA 417
           G + N RL + F  EIG  ++ LL+HT++RWLS+G+IL+ ++E+  EI+ FL  K S+L 
Sbjct: 303 GRAPNHRLFQAFFEEIGIEYSVLLFHTEMRWLSRGQILTHIFEMYEEINQFLHHKSSNLV 362

Query: 418 SIFEDDTWVTKLAYLTDIFSILNELSLKLQGKNSDVFQHVERIQGFRKTLLLWQVRLKSN 477
             FE+  +   LAYL D+F  LNELS  +Q    +     E++  F +    WQ R++  
Sbjct: 363 DGFENKEFKIHLAYLADLFKHLNELSASMQRTGMNTVSAREKLSAFVRKFPFWQKRIEKR 422

Query: 478 RPSYYMFPRFLQHIEENIINENILKEIKLEILLHLTSLSQTFNHFFPEEKFETLRENS-W 536
             + + F      +EE I+++N    I  EI LHL  LS  F+ +F       L E S W
Sbjct: 423 NFTNFPF------LEEIIVSDNEGIFIAAEITLHLQQLSNFFHGYF---SIGDLNEASKW 473

Query: 537 VKDPFAFRHPESIIELNLVPEE---ENELLQLSSSYTLKNDYETLSLSAFWMKVKEDFPL 593
           + DPF F        ++ V +    +N+L +L +S  +  ++ET+ L  FW      FP 
Sbjct: 474 ILDPFLF-------NIDFVDDSYLMKNDLAELRASGQILMEFETMKLEDFWCAQFTAFPN 526

Query: 594 LSRKSVLLLLPFTTTSLCELGFSILTQLKTKERNGLNCAAVMRVALSSCVPDWNELMNRQ 653
           L++ ++ +L+PF TT LCELGFS L   KTK R+  N +  +RVA+S  VP +++++ ++
Sbjct: 527 LAKTALEILMPFATTYLCELGFSSLLHFKTKSRSCFNLSDDIRVAISKKVPRFSDIIEQK 586


>gi|51241788 GTF2I repeat domain containing 2B [Homo sapiens]
          Length = 949

 Score =  148 bits (373), Expect = 2e-35
 Identities = 139/550 (25%), Positives = 247/550 (44%), Gaps = 72/550 (13%)

Query: 84  PQCVICNNILANESLKPSKLKRHLETQHAELIDKPLEYFQRKK-KDIKLSTQFLSCSTAV 142
           P C+IC   ++    K   L+RH +T H++  D+  E  + +K  ++K   +        
Sbjct: 445 PTCLICKQSMSVS--KEYNLRRHYQTNHSKHYDQYTERMRDEKLHELKKGLR-------- 494

Query: 143 SEKALLSSYLVAYRVAKEKIANTAAEKIILPACLDMVRTIFDDKSADKLKTIPNDNTVSL 202
             K LL S        K+  AN +      P     V+ + D                  
Sbjct: 495 --KYLLGSSDTECPEQKQVFANPS------PTQKSPVQPVED------------------ 528

Query: 203 RICTIAEHLETMLITRLQSGIDFAIQLDESTDIGSCTTLLVYVRYAWQD-DFLEDFLCFL 261
               +A +L   L  +++S + ++I +DE TDI + T L +++R   ++ D  E+ L  +
Sbjct: 529 ----LAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTV 584

Query: 262 NLTSHLSGLDIFTELERRIVGQYKLNWKNCKGITSDGTATMTGKHSRVIKKL---LEVTN 318
            +T   SG +IF  +E+ +  ++ +NW     + S GT  M   ++ ++ KL   +    
Sbjct: 585 PMTGTKSGNEIFLRVEKSLK-KFCINWSRLVSVASTGTPAMVDANNGLVTKLKSRVATFC 643

Query: 319 NGAVWNH--CFIHREGLASREIPQNLMEVLKNAVKVVNFIKGSSLNSRLLETFCSEIGTN 376
            GA      C IH E L ++++  +   V+   VK VN+I    LN     T   E+ + 
Sbjct: 644 KGAELKSICCIIHPESLCAQKLKMD--HVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQ 701

Query: 377 HTHLLYHTKIRWLSQGKILSRVYELRNEIHFFLIEKKSHLASIFEDDTWVTKLAYLTDIF 436
           +  LLY+T+I+WLS+G +L R +E   EI  F+  +   L  +   D W+  LA+L D+ 
Sbjct: 702 YGSLLYYTEIKWLSRGLVLKRFFESLEEIDSFMSSRGKPLPQLSSID-WIRDLAFLVDMT 760

Query: 437 SILNELSLKLQGKNSDVFQHVERIQGFRKTLLLWQVRLKSNRPSYYMFPRFLQHIEENII 496
             LN L++ LQG +  V Q  + I+ F   L LW+  L  N  +++   + +   E + +
Sbjct: 761 MHLNALNISLQGHSQIVTQMYDLIRAFLAKLCLWETHLTRNNLAHFPTLKLVSRNESDGL 820

Query: 497 NE-NILKEIKLEILLHLTSLSQTFNHFFPEEKFETLRENSWVKDPFAFRHPESIIELNLV 555
           N    + E+K E    L+            + +E+  E +    PF+        +++ V
Sbjct: 821 NYIPKIAELKTEFQKRLSDF----------KLYES--ELTLFSSPFS-------TKIDSV 861

Query: 556 PEE-ENELLQLSSSYTLKNDYETLSLSAFWMKVKEDFPLLSRKSVLLLLPFTTTSLCELG 614
            EE + E++ L  +  LK  Y+ + +  F+  +   +P        +L  F +T +CE  
Sbjct: 862 HEELQMEVIDLQCNTVLKTKYDKVGIPEFYKYLWGSYPKYKHHCAKILSMFGSTYICEQL 921

Query: 615 FSILTQLKTK 624
           FSI+   KTK
Sbjct: 922 FSIMKLSKTK 931


>gi|48762700 GTF2I repeat domain containing 2 [Homo sapiens]
          Length = 949

 Score =  146 bits (369), Expect = 5e-35
 Identities = 137/549 (24%), Positives = 248/549 (45%), Gaps = 70/549 (12%)

Query: 84  PQCVICNNILANESLKPSKLKRHLETQHAELIDKPLEYFQRKKKDIKLSTQFLSCSTAVS 143
           P C+IC   ++    K   L+RH +T H++  D+ +E    + +D KL            
Sbjct: 445 PTCLICKQSMSVS--KEYNLRRHYQTNHSKHYDQYME----RMRDEKLHEL--------- 489

Query: 144 EKALLSSYLVAYRVAKEKIANTAAEKIILPACLDMVRTIFDDKSADKLKTIPNDNTVSLR 203
            K  L  YL+        +++T         C +  +         K    P ++     
Sbjct: 490 -KKGLRKYLLG-------LSDTE--------CPEQKQVFAHPSPTQKSPVQPVED----- 528

Query: 204 ICTIAEHLETMLITRLQSGIDFAIQLDESTDIGSCTTLLVYVRYAWQD-DFLEDFLCFLN 262
              +A +L   L  +++S + ++I +DE TDI + T L +++R   ++ D  E+ L  + 
Sbjct: 529 ---LAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVP 585

Query: 263 LTSHLSGLDIFTELERRIVGQYKLNWKNCKGITSDGTATMTGKHSRVIKKL---LEVTNN 319
           +T   SG +IF+ +E+ +  ++ ++W     + S GT  M   ++ ++ KL   +     
Sbjct: 586 MTGTKSGNEIFSRVEKSLK-KFCIDWSKLVSVASTGTPAMVDANNGLVTKLKSRVATFCK 644

Query: 320 GAVWNH--CFIHREGLASREIPQNLMEVLKNAVKVVNFIKGSSLNSRLLETFCSEIGTNH 377
           GA      C IH E L ++++  +   V+   VK VN+I    LN     T   E+ + +
Sbjct: 645 GAELKSICCIIHPESLCAQKLKMD--HVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQY 702

Query: 378 THLLYHTKIRWLSQGKILSRVYELRNEIHFFLIEKKSHLASIFEDDTWVTKLAYLTDIFS 437
             LLY+T+I+WLS+G +L R +E   EI  F+  +   L  +   D W+  LA+L D+  
Sbjct: 703 GSLLYYTEIKWLSRGLVLKRFFESLEEIDSFMSSRGKPLPQLSSID-WIRDLAFLVDMTM 761

Query: 438 ILNELSLKLQGKNSDVFQHVERIQGFRKTLLLWQVRLKSNRPSYYMFPRFLQHIEENIIN 497
            LN L++ LQG +  V Q  + I+ F   L LW+  L  N  +++   +     E + +N
Sbjct: 762 HLNALNISLQGHSQIVTQMYDLIRAFLAKLCLWETHLTRNNLAHFPTLKLASRNESDGLN 821

Query: 498 E-NILKEIKLEILLHLTSLSQTFNHFFPEEKFETLRENSWVKDPFAFRHPESIIELNLVP 556
               + E+K E    L+            + +E+  E +    PF+        +++ V 
Sbjct: 822 YIPKIAELKTEFQKRLSDF----------KLYES--ELTLFSSPFS-------TKIDSVH 862

Query: 557 EE-ENELLQLSSSYTLKNDYETLSLSAFWMKVKEDFPLLSRKSVLLLLPFTTTSLCELGF 615
           EE + E++ L  +  LK  Y+ + +  F+  +   +P        +L  F +T +CE  F
Sbjct: 863 EELQMEVIDLQCNTVLKTKYDKVGIPEFYKYLWGSYPKYKHHCAKILSMFGSTYICEQLF 922

Query: 616 SILTQLKTK 624
           SI+   KTK
Sbjct: 923 SIMKLSKTK 931


>gi|7662294 EPM2A interacting protein 1 [Homo sapiens]
          Length = 607

 Score =  110 bits (275), Expect = 4e-24
 Identities = 125/598 (20%), Positives = 251/598 (41%), Gaps = 46/598 (7%)

Query: 77  KPFENDRPQCVICNNILANESLKPSKLKRHLETQHAELIDKPLEYFQRKKKD-------I 129
           +P E D   C++C  ++   + +   ++RH E +H        EY++R   D        
Sbjct: 30  EPPEGDGALCLVCRRLIV--ATRERDVRRHYEAEH--------EYYERYVADGERAALVE 79

Query: 130 KLSTQFLSCSTAVSEKALLSSYLVAYRVAKEKIANTAAEKIILPACLDMVRTIFDDKSAD 189
           +L    L  ++   E+    + L   R+   K         +      ++R +  +  + 
Sbjct: 80  RLRQGDLPVASFTPEERAARAGLGLCRLLALKGRGWGEGDFVYQCMEVLLREVLPEHVSV 139

Query: 190 KLKTIPNDNTVSLRICTIAEHLETMLITRLQSGIDFAIQLDESTDIGSCTTLLVYVRYAW 249
                 + +    RI +I  +L   L  R +    +++ LD+   +     LLV++R   
Sbjct: 140 LQGVDLSPDITRQRILSIDRNLRNQLFNRARDFKAYSLALDDQAFVAYENYLLVFIRGVG 199

Query: 250 QD-DFLEDFLCFLNLTSHLSGLDIFTELERRIVGQYKLNWKNCKGITSDGTATMTGKHSR 308
            + +  ED L  +NLT H S   + + +   +     L+ +   G+T+  T  M G++S 
Sbjct: 200 PELEVQEDLLTIINLTHHFSVGALMSAILESLQTA-GLSLQRMVGLTTTHTLRMIGENSG 258

Query: 309 VIKKLLEVTNNGAVWNHC----FIHREGLASREIPQNLMEVLKNAVKVVNFIKGSSLNSR 364
           ++  + E   +   WN      F+H E L+S ++  N  +++    + +  IK   +   
Sbjct: 259 LVSYMREKAVSPNCWNVIHYSGFLHLELLSSYDVDVN--QIINTISEWIVLIKTRGVRRP 316

Query: 365 LLETFCSEIGTNHTHLLYHTKIR-WLSQGKILSRVYELRNEIHFFLIEKKSHLASIFEDD 423
             +T  +E  + H   +    +  WL +GK L  ++ LR E+  FL+   +     F D 
Sbjct: 317 EFQTLLTESESEHGERVNGRCLNNWLRRGKTLKLIFSLRKEMEAFLVSVGATTVH-FSDK 375

Query: 424 TWVTKLAYLTDIFSILNELSLKLQGKNSDVFQHVERIQGFRKTLLLWQVRLKSNRPSYYM 483
            W+    +L DI   L ELS +L+          + I  F   L L+Q  ++    +   
Sbjct: 376 QWLCDFGFLVDIMEHLRELSEELRVSKVFAAAAFDHICTFEVKLNLFQRHIEEK--NLTD 433

Query: 484 FPRFLQHIEE----NIINENILKEIKLEILLHLTSLSQTFNHFFPEEKFETLRENSWVKD 539
           FP   + ++E    N  +E I    + +++  +  L + F   F + +F   ++     +
Sbjct: 434 FPALREVVDELKQQNKEDEKIFDPDRYQMV--ICRLQKEFERHFKDLRF-IKKDLELFSN 490

Query: 540 PFAFRHPESIIELNLVPEEENELLQLSSSYTLKNDYETLSLSAFWMKVK-EDFPLLSRKS 598
           PF F+   + I + +      EL +L ++  L N+Y    L  F+  +  E +P++   +
Sbjct: 491 PFNFKPEYAPISVRV------ELTKLQANTNLWNEYRIKDLGQFYAGLSAESYPIIKGVA 544

Query: 599 VLLLLPFTTTSLCELGFSILTQLK---TKERNGLNCAAVMRVALSSCVPDWNELMNRQ 653
             +   F +  +CE  FS LT+ +   ++     +  A+ RVA +   P W++L+  +
Sbjct: 545 CKVASLFDSNQICEKAFSYLTRNQHTLSQPLTDEHLQALFRVATTEMEPGWDDLVRER 602


>gi|55741653 hypothetical protein LOC57691 [Homo sapiens]
          Length = 787

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 59/263 (22%), Positives = 109/263 (41%), Gaps = 19/263 (7%)

Query: 207 IAEHLETMLITRLQSGI-----DFAIQLDESTDIGSCTTLLVYVRYAWQDDFLED--FLC 259
           IAEH+   +  ++   I        I +DE++ +   TTL++Y++   Q        F+ 
Sbjct: 291 IAEHIAKEMKMKIFKNIIEENAKICIIIDEASTVSKKTTLVIYLQCTIQSAPAPVMLFVA 350

Query: 260 FLNLTSHLSGLDIFTEL----ERRIVGQYKLNWKNCKGITSDGTATMTGKHSRVIKKLLE 315
              L S ++   + T L    +     +Y     N     SDG  T+ G+ S V  KLLE
Sbjct: 351 LKELVSTIAECIVNTLLTTLNDCGFTNEYLK--ANLIAFCSDGANTILGRKSGVATKLLE 408

Query: 316 VTNNGAVWNHCFIHREGLASREIPQNLMEV--LKNAVKVVNFI--KGSSLNSRLLETFCS 371
                 +WN C  HR  L+  +    + ++  LK  +  +  I  + +   ++LL T   
Sbjct: 409 NFPEIIIWN-CLNHRLQLSLDDSISEIKQINHLKIFIDKIYSIYHQPNKNQTKLLGTVAK 467

Query: 372 EIGTNHTHLLYHTKIRWLSQG-KILSRVYELRNEIHFFLIEKKSHLASIFEDDTWVTKLA 430
           E+ T    +      RW +   +  + V+     ++       S LA    +  ++  LA
Sbjct: 468 ELETEIIKIGRVMGPRWAACSLQAATAVWHAYPILYMHFSHSYSGLAKRLANINFLQDLA 527

Query: 431 YLTDIFSILNELSLKLQGKNSDV 453
            + DI    + LS  LQ +++++
Sbjct: 528 LMIDILEEFSVLSTALQSRSTNI 550


>gi|113205089 zinc finger, MYM domain containing 1 [Homo sapiens]
          Length = 1142

 Score = 40.4 bits (93), Expect = 0.005
 Identities = 57/275 (20%), Positives = 115/275 (41%), Gaps = 29/275 (10%)

Query: 215 LITRLQSGIDFAIQLDESTDIGSCTTLLVYVRYAWQDD----FLEDFLCFLNLTSHLSGL 270
           ++  +     F+I  DE+ +      L + VRY  +        E FL F++ T  ++G 
Sbjct: 633 IVNEINDSSAFSIICDETINSAMKEQLSICVRYPQKSSKAILIKERFLGFVD-TEEMTG- 690

Query: 271 DIFTELERRI---VGQYKLNWKNCKGITSDGTATMTGKHSRVIKKLLEVTNNGAVWNHCF 327
              T L R I   + Q  ++     G   D T  +  K +++  +  +     A++ HC+
Sbjct: 691 ---THLHRTIKTYLQQIGVDMDKIHGQAYDSTTNLKIKFNKIAAEFKKEEPR-ALYIHCY 746

Query: 328 IHREGLASREIPQNLMEVLKNAVKVVNFIKGS-SLNSRLLETFCS--EIGTNHTHLLYHT 384
            H   L+     + + E L++A+K ++ +  +  ++  +L  F +   +  N T   + +
Sbjct: 747 AHFLDLSIIRFCKEVKE-LRSALKTLSSLFNTICMSGEMLANFRNIYRLSQNKTCKKHIS 805

Query: 385 KIRWLSQGKILSRVYELRNEI------------HFFLIEKKSHLASIFEDDTWVTKLAYL 432
           +  W    + L  V +   EI            +    ++ SHL ++     +V  L +L
Sbjct: 806 QSCWTVHDRTLLSVIDSLPEIIETLEVIASHSSNTSFADELSHLLTLVSKFEFVFCLKFL 865

Query: 433 TDIFSILNELSLKLQGKNSDVFQHVERIQGFRKTL 467
             + S+   LS +LQ K  D+F    +I+   + L
Sbjct: 866 YRVLSVTGILSKELQNKTIDIFSLSSKIEAILECL 900


>gi|149773449 zinc finger protein 862 [Homo sapiens]
          Length = 1169

 Score = 39.3 bits (90), Expect = 0.012
 Identities = 100/481 (20%), Positives = 179/481 (37%), Gaps = 85/481 (17%)

Query: 207  IAEHLETMLITRLQSGIDFAIQLDESTDIGSCTTLLVYVRYAWQDDFLEDFLCFLNLTSH 266
            I+E L+  ++  +++    ++ LD STD      + +Y+RY  Q +  E ++    L S 
Sbjct: 606  ISETLKREILEDVRNSPCVSVLLDSSTDASEQACVGIYIRYFKQMEVKESYITLAPLYSE 665

Query: 267  LSG---LDIFTELERRIVGQYKLNWKNCKGITSDGTATMT------GKHSRVIKKLLEVT 317
             +      I + L+   +   K  W    G+ +DG+A ++       K   VI +LL V 
Sbjct: 666  TADGYFETIVSALDELDIPFRKPGW--VVGLGTDGSAMLSCRGGLVEKFQEVIPQLLPV- 722

Query: 318  NNGAVWNHCFIHREGLASREIPQNLMEVLK---NAVKVVNFIKGSSLNSRLLETFCSEIG 374
                   HC  HR  LA  +   ++  V K   +   V  F + S+     L+   + + 
Sbjct: 723  -------HCVAHRLHLAVVDACGSIDLVKKCDRHIRTVFKFYQSSNKRLNELQEGAAPLE 775

Query: 375  TNHTHLLYHTKIRWLSQ---------------GKILSRVYELRNEIHFFLIEKKSHLASI 419
                 L     +RW++                 + L RV E   +I      +   +  +
Sbjct: 776  QEIIRLKDLNAVRWVASRRRTLHALLVSWPALARHLQRVAEAGGQIG----HRAKGMLKL 831

Query: 420  FEDDTWVTKLAYLTDIFSILNELSLKLQGKNSDVFQHVERIQGFRKTLLLWQVRLKSNRP 479
                 +V    +L D  SI   LS   Q K   +   V    G R  + L  +R ++   
Sbjct: 832  MRGFHFVKFCHFLLDFLSIYRPLSEVCQ-KEIVLITEVNATLG-RAYVALESLRHQAGPK 889

Query: 480  SYYMFPRF---------LQHIEENIINENILKEIKLEILLHLTSLSQTFNHFFPEEKFET 530
                   F         L  +E  +  +    + +  +L  +  L Q F+   P +    
Sbjct: 890  EEEFNASFKDGRLHGICLDKLE--VAEQRFQADRERTVLTGIEYLQQRFDADRPPQ---- 943

Query: 531  LRENSWVKDPFAFRHPESIIELNLVPEEENELLQLSSSY--TLKNDYETLSLSAFWMKVK 588
              +N  V D  A+  P  I    L     +++L L+  +  +L   Y   +L   W+ +K
Sbjct: 944  -LKNMEVFDTMAW--PSGI---ELASFGNDDILNLARYFECSLPTGYSEEALLEEWLGLK 997

Query: 589  E-------------------DFPLLSRKSVLLLLPFTTTSLCELGFSILTQLKTKERNGL 629
                                 FPLLS+   +++    +TS CE GF  + +++T ER  L
Sbjct: 998  TIAQHLPFSMLCKNALAQHCRFPLLSKLMAVVVCVPISTSCCERGFKAMNRIRTDERTKL 1057

Query: 630  N 630
            +
Sbjct: 1058 S 1058


>gi|21361633 leucine rich repeat containing 40 [Homo sapiens]
          Length = 602

 Score = 36.2 bits (82), Expect = 0.098
 Identities = 38/133 (28%), Positives = 55/133 (41%), Gaps = 7/133 (5%)

Query: 327 FIHREGLASREIPQNLMEVLKNAVKVVNFIKGSSLNSRLLETFCSEI-GTNHTHLLY--H 383
           F     L    +  N ++ L   +  +  +K    NS LLET   E+ G     LLY   
Sbjct: 193 FSSLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRR 252

Query: 384 TKIRWLSQGKILSRVYELR---NEIHFFLIEKKSHLASIFEDDTWVTKLAYLTDIFSILN 440
            K+R+L +    S + EL    N+I     E   HL SI   D    KL  + D   +L 
Sbjct: 253 NKLRFLPEFPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEIILLR 312

Query: 441 ELSLKLQGKNSDV 453
            L  +L   N+D+
Sbjct: 313 SLE-RLDLSNNDI 324


>gi|33188431 tetratricopeptide repeat protein isoform 3 [Homo
           sapiens]
          Length = 1347

 Score = 34.7 bits (78), Expect = 0.29
 Identities = 21/85 (24%), Positives = 37/85 (43%), Gaps = 3/85 (3%)

Query: 560 NELLQLSSSYTLKNDYETLSLSAFWMKVKEDFPLLSRKSVLLLLPFTTTSLCELGFSILT 619
           N +  L+S ++  +      L       K D PL S +S   +LP  + S+C     +L 
Sbjct: 786 NSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSSTEVLK 845

Query: 620 QLKTKERNGLNCAAVMRVALSSCVP 644
             +   +NGL+ + ++   L  C P
Sbjct: 846 ACRNPGKNGLSNSCIL---LDKCPP 867


>gi|33188429 tetratricopeptide repeat protein isoform 1 [Homo
           sapiens]
          Length = 1079

 Score = 34.7 bits (78), Expect = 0.29
 Identities = 21/85 (24%), Positives = 37/85 (43%), Gaps = 3/85 (3%)

Query: 560 NELLQLSSSYTLKNDYETLSLSAFWMKVKEDFPLLSRKSVLLLLPFTTTSLCELGFSILT 619
           N +  L+S ++  +      L       K D PL S +S   +LP  + S+C     +L 
Sbjct: 786 NSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSSTEVLK 845

Query: 620 QLKTKERNGLNCAAVMRVALSSCVP 644
             +   +NGL+ + ++   L  C P
Sbjct: 846 ACRNPGKNGLSNSCIL---LDKCPP 867


>gi|33188427 tetratricopeptide repeat protein isoform 2 [Homo
           sapiens]
          Length = 1240

 Score = 34.7 bits (78), Expect = 0.29
 Identities = 21/85 (24%), Positives = 37/85 (43%), Gaps = 3/85 (3%)

Query: 560 NELLQLSSSYTLKNDYETLSLSAFWMKVKEDFPLLSRKSVLLLLPFTTTSLCELGFSILT 619
           N +  L+S ++  +      L       K D PL S +S   +LP  + S+C     +L 
Sbjct: 786 NSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSSTEVLK 845

Query: 620 QLKTKERNGLNCAAVMRVALSSCVP 644
             +   +NGL+ + ++   L  C P
Sbjct: 846 ACRNPGKNGLSNSCIL---LDKCPP 867


>gi|239752520 PREDICTED: similar to Rap guanine nucleotide exchange
           factor 2, partial [Homo sapiens]
          Length = 803

 Score = 34.3 bits (77), Expect = 0.37
 Identities = 31/106 (29%), Positives = 51/106 (48%), Gaps = 20/106 (18%)

Query: 546 PESIIELNLVPEEENEL---LQLSSSYTLKNDYETLSLSAFWMKVKEDFPLLSRKSVLLL 602
           PE +I+   +P++ ++L   +QLS  Y LKN+ ET +L +      ED   L R+S + L
Sbjct: 659 PEGVIKQRRLPDQLSKLADRIQLSGRYYLKNNMETETLCS-----DEDAQELLRESQISL 713

Query: 603 LPFTT----TSLCELGFSILTQLKTKE--------RNGLNCAAVMR 636
           L  +T    T L    F +   ++  E        R+  +CA + R
Sbjct: 714 LQLSTVEVATQLSMRNFELFRNIEPTEYIDDLFKLRSKTSCANLKR 759


>gi|7657261 Rap guanine nucleotide exchange factor 2 [Homo sapiens]
          Length = 1499

 Score = 34.3 bits (77), Expect = 0.37
 Identities = 31/106 (29%), Positives = 51/106 (48%), Gaps = 20/106 (18%)

Query: 546 PESIIELNLVPEEENEL---LQLSSSYTLKNDYETLSLSAFWMKVKEDFPLLSRKSVLLL 602
           PE +I+   +P++ ++L   +QLS  Y LKN+ ET +L +      ED   L R+S + L
Sbjct: 659 PEGVIKQRRLPDQLSKLADRIQLSGRYYLKNNMETETLCS-----DEDAQELLRESQISL 713

Query: 603 LPFTT----TSLCELGFSILTQLKTKE--------RNGLNCAAVMR 636
           L  +T    T L    F +   ++  E        R+  +CA + R
Sbjct: 714 LQLSTVEVATQLSMRNFELFRNIEPTEYIDDLFKLRSKTSCANLKR 759


>gi|87299628 biorientation of chromosomes in cell division 1-like
           [Homo sapiens]
          Length = 3051

 Score = 33.1 bits (74), Expect = 0.83
 Identities = 18/51 (35%), Positives = 26/51 (50%)

Query: 18  EACSSSSVESGIVNSDNIEKNTDSNLQTSTSFEPHFKKKKVSARRYNEDYL 68
           E  +S S+E G + SD+ EKN  +  +T TS     K K V     ++ YL
Sbjct: 426 EVVTSDSMEEGEITSDDEEKNKQNKTKTQTSDSSEGKTKSVRHAYVHKPYL 476


>gi|119395734 breast cancer 2, early onset [Homo sapiens]
          Length = 3418

 Score = 32.0 bits (71), Expect = 1.9
 Identities = 45/219 (20%), Positives = 83/219 (37%), Gaps = 15/219 (6%)

Query: 29   IVNSDNIEKNTDSNLQTSTSFEPHFKKKKVSARRYNE-DYLKYGFIKCEKPFENDRPQCV 87
            IVN  + +     N   ++      +K K+    Y E D +K+  +K   P         
Sbjct: 1446 IVNFFDQKPEELHNFSLNSELHSDIRKNKMDILSYEETDIVKHKILKESVPVGTGNQLVT 1505

Query: 88   ICNNILANESLK-PSKLKRHLETQHA-----ELIDKPLEYFQRKKKDIKLSTQFLSCSTA 141
                   +E +K P+ L  H  +        E +DK    F  K++     T F   S  
Sbjct: 1506 FQGQPERDEKIKEPTLLGFHTASGKKVKIAKESLDKVKNLFDEKEQGTSEITSF---SHQ 1562

Query: 142  VSEKALLSSYLVAYRVAKEKIANTAAEKIILPACLDMVRTIFDDKSADKLKTIPNDNTVS 201
             ++            +A E I  TAA     P C +M  ++ +DK+   ++T+     +S
Sbjct: 1563 WAKTLKYREACKDLELACETIEITAA-----PKCKEMQNSLNNDKNLVSIETVVPPKLLS 1617

Query: 202  LRICTIAEHLETMLITRLQSGIDFAIQLDESTDIGSCTT 240
              +C   E+L+T     L+  +   ++ + +    +C T
Sbjct: 1618 DNLCRQTENLKTSKSIFLKVKVHENVEKETAKSPATCYT 1656


>gi|54633319 PDZ domain-containing guanine nucleotide exchange
           factor I [Homo sapiens]
          Length = 1601

 Score = 31.2 bits (69), Expect = 3.2
 Identities = 24/83 (28%), Positives = 43/83 (51%), Gaps = 15/83 (18%)

Query: 546 PESIIELNLVPEEENEL---LQLSSSYTLKNDYETLSLSAFWMKVKEDFPLLSRKSVLLL 602
           PE +I+   +P++ ++L   +QL+  Y LKN+ ET +L +      ED   L ++S L +
Sbjct: 802 PEGVIKQRRLPDQFSKLADRIQLNGRYYLKNNMETETLCS-----DEDAQELVKESQLSM 856

Query: 603 LPFTTTSLCELGFSILTQLKTKE 625
           L  +T         + TQL  ++
Sbjct: 857 LQLST-------IEVATQLSMRD 872


>gi|23503283 TBC1 domain family, member 21 [Homo sapiens]
          Length = 336

 Score = 31.2 bits (69), Expect = 3.2
 Identities = 13/47 (27%), Positives = 30/47 (63%), Gaps = 1/47 (2%)

Query: 461 QGFRKTLLLWQVRLKSNRPSYYMFPRFLQHIEEN-IINENILKEIKL 506
           QGF + ++L+Q+ ++ +  ++++F  FLQ  E + +IN  + K + +
Sbjct: 163 QGFHEMMMLFQLMVEHDHETFWLFQFFLQKTEHSCVINIGVAKNLDM 209


>gi|66773040 phosphatidic acid phosphatase type 2 domain containing
           2 [Homo sapiens]
          Length = 295

 Score = 31.2 bits (69), Expect = 3.2
 Identities = 18/55 (32%), Positives = 28/55 (50%), Gaps = 4/55 (7%)

Query: 308 RVIKKLLEVTNNGAVWN----HCFIHREGLASREIPQNLMEVLKNAVKVVNFIKG 358
           R + KLLE++ +G  W     +C    +  A RE+  NL+  L   + +V  IKG
Sbjct: 131 RPLMKLLEISGHGIPWLLGTLYCLCRSDSWAGREVLMNLLFALLLDLLLVALIKG 185


>gi|156627573 zinc finger protein 836 [Homo sapiens]
          Length = 936

 Score = 30.8 bits (68), Expect = 4.1
 Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 4/80 (5%)

Query: 489 QHIEENIINENILKEIKLEILLHLTSLS--QTFNHFFPEEKFETLRENSWVKDPFAFRHP 546
           QH +E++ N+ I  ++ L     LT L   QT    +   + E    NS +  P     P
Sbjct: 126 QHSQEDVENKCIENQLTLSFQSRLTELQKFQTEGKIYECNQSEKTVNNSSLVSPLQRILP 185

Query: 547 ESIIELNLVPEEENELLQLS 566
              ++ N+  + ENE LQLS
Sbjct: 186 S--VQTNISKKYENEFLQLS 203


>gi|62899047 RAD50 interactor 1 [Homo sapiens]
          Length = 792

 Score = 30.4 bits (67), Expect = 5.4
 Identities = 33/112 (29%), Positives = 48/112 (42%), Gaps = 32/112 (28%)

Query: 335 SREIPQNLMEVLKNAVKVVNFIKG---------SSLNSRLLE---------TFCSEIGTN 376
           S EIP+ +   LKNA +   F+           S++NS LL          T  S+I   
Sbjct: 96  SSEIPKRIRSALKNAEESKQFLNQFLEQETHLFSAINSHLLTAQPWMDDLGTMISQIEEI 155

Query: 377 HTHLLYHTKIRWLSQGKILSRVYELRNEIHFFLI-----EKKSHLASIFEDD 423
             HL Y   ++W+SQ      + EL + I  +L+     E  S L S+ E D
Sbjct: 156 ERHLAY---LKWISQ------IEELSDNIQQYLMTNNVPEAASTLVSMAELD 198


>gi|21450836 zinc finger with UFM1-specific peptidase domain [Homo
           sapiens]
          Length = 578

 Score = 30.4 bits (67), Expect = 5.4
 Identities = 26/105 (24%), Positives = 48/105 (45%), Gaps = 12/105 (11%)

Query: 22  SSSVESGIVNSDNIEKNTDSNLQTSTSF--EPHFKKKKVSARRYNEDYLKYGFIKCEKPF 79
           +SS+ SG  +  N  KN+  NL   ++   E  + +    +R++ +   K   +   K  
Sbjct: 88  NSSILSGCAS--NHPKNSAQNLTKDSTLKHEGFYSENLTESRKFLKSREKQSSLTEIKGS 145

Query: 80  ENDR----PQCVICNNILANESLKPSKLKRHLETQHAELIDKPLE 120
             +     P+C  C  I  +       ++ H++T+HA L+D PLE
Sbjct: 146 VYETTYSPPECPFCGKIEEHSE----DMETHVKTKHANLLDIPLE 186


>gi|226246537 zinc finger protein 407 isoform 3 [Homo sapiens]
          Length = 1660

 Score = 30.0 bits (66), Expect = 7.1
 Identities = 19/91 (20%), Positives = 37/91 (40%), Gaps = 18/91 (19%)

Query: 39   TDSNLQTSTSFEPHFKKKKVSARRYNEDYLKYGFIKCEKPFENDRPQCVICNNILANESL 98
            T+SNL    +   H + ++ S     E    +  +KC +PF++++               
Sbjct: 1455 TESNLHQHLASAGHMRNEQASVEELPEGGATFKCVKCTEPFDSEQ--------------- 1499

Query: 99   KPSKLKRHLETQHAELIDKPLEYFQRKKKDI 129
                L  H++ QH EL+ +  +Y     + I
Sbjct: 1500 ---NLFLHIKGQHEELLREVNKYIVEDTEQI 1527


>gi|226246535 zinc finger protein 407 isoform 2 [Homo sapiens]
          Length = 1815

 Score = 30.0 bits (66), Expect = 7.1
 Identities = 19/91 (20%), Positives = 37/91 (40%), Gaps = 18/91 (19%)

Query: 39   TDSNLQTSTSFEPHFKKKKVSARRYNEDYLKYGFIKCEKPFENDRPQCVICNNILANESL 98
            T+SNL    +   H + ++ S     E    +  +KC +PF++++               
Sbjct: 1455 TESNLHQHLASAGHMRNEQASVEELPEGGATFKCVKCTEPFDSEQ--------------- 1499

Query: 99   KPSKLKRHLETQHAELIDKPLEYFQRKKKDI 129
                L  H++ QH EL+ +  +Y     + I
Sbjct: 1500 ---NLFLHIKGQHEELLREVNKYIVEDTEQI 1527


>gi|134133288 zinc finger protein 407 isoform 1 [Homo sapiens]
          Length = 2248

 Score = 30.0 bits (66), Expect = 7.1
 Identities = 19/91 (20%), Positives = 37/91 (40%), Gaps = 18/91 (19%)

Query: 39   TDSNLQTSTSFEPHFKKKKVSARRYNEDYLKYGFIKCEKPFENDRPQCVICNNILANESL 98
            T+SNL    +   H + ++ S     E    +  +KC +PF++++               
Sbjct: 1455 TESNLHQHLASAGHMRNEQASVEELPEGGATFKCVKCTEPFDSEQ--------------- 1499

Query: 99   KPSKLKRHLETQHAELIDKPLEYFQRKKKDI 129
                L  H++ QH EL+ +  +Y     + I
Sbjct: 1500 ---NLFLHIKGQHEELLREVNKYIVEDTEQI 1527


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.134    0.392 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,851,656
Number of Sequences: 37866
Number of extensions: 953299
Number of successful extensions: 2639
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 2569
Number of HSP's gapped (non-prelim): 41
length of query: 657
length of database: 18,247,518
effective HSP length: 109
effective length of query: 548
effective length of database: 14,120,124
effective search space: 7737827952
effective search space used: 7737827952
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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