Guide to the Human Genome
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Name: MBD1 Sequence: fasta or formatted (556aa) NCBI GI: 21464119
Description:

methyl-CpG binding domain protein 1 isoform PCM1

Referenced in:

DNA Methylation
Fibroblast Growth Factors

Other entries for this name:
alt prot [549aa] methyl-CpG binding domain protein 1 isoform 3
alt prot [586aa] methyl-CpG binding domain protein 1 isoform 2
alt prot [605aa] methyl-CpG binding domain protein 1 isoform 1
alt prot [503aa] methyl-CpG binding domain protein 1 isoform 4
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.6         48           2
 C cysteine            5.4         30           2
 D aspartate           5.4         30           2
 E glutamate           5.6         31           3
 F phenylalanine       2.7         15           1
 G glycine             8.1         45           3
 H histidine           1.3          7           2
 I isoleucine          1.4          8           1
 K lysine              7.2         40           2
 L leucine             6.5         36           2
 M methionine          0.9          5           1
 N asparagine          1.1          6           1
 P proline            11.3         63           5
 Q glutamine           5.6         31           1
 R arginine           10.1         56           3
 S serine              6.1         34           2
 T threonine           5.4         30           1
 V valine              4.5         25           2
 W tryptophan          1.4          8           1
 Y tyrosine            1.4          8           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   methyl-CpG binding domain protein 1 isoform PCM1 [Ho... 
MBD1                  0.980   methyl-CpG binding domain protein 1 isoform 1 
MBD1                  0.836   methyl-CpG binding domain protein 1 isoform 3 [Homo...
MBD1                  0.788   methyl-CpG binding domain protein 1 isoform 2 
MBD1                  0.720   methyl-CpG binding domain protein 1 isoform 4 
MBD2                  0.053   methyl-CpG binding domain protein 2 testis-specific i...
MBD2                  0.053   methyl-CpG binding domain protein 2 isoform 1 
MLL                   0.048   myeloid/lymphoid or mixed-lineage leukemia protein [...
CXXC1                 0.047   CXXC finger 1 (PHD domain) isoform 1 
CXXC1                 0.047   CXXC finger 1 (PHD domain) isoform 2 
MBD3                  0.042   methyl-CpG binding domain protein 3 
MLL4                  0.036   myeloid/lymphoid or mixed-lineage leukemia 4 
DNMT1                 0.029   DNA (cytosine-5-)-methyltransferase 1 isoform a [Ho...
DNMT1                 0.029   DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo...
KDM2B                 0.026   F-box and leucine-rich repeat protein 10 isoform a [...
KDM2B                 0.026   F-box and leucine-rich repeat protein 10 isoform b [...
MECP2                 0.025   methyl CpG binding protein 2 isoform 2 
MECP2                 0.025   methyl CpG binding protein 2 isoform 1 
FBXL19                0.023   F-box and leucine-rich repeat protein 19 
KDM2A                 0.023   F-box and leucine-rich repeat protein 11 
ESPN                  0.015   espin 
ZNF579                0.015   zinc finger protein 579 
TET1                  0.015   CXXC finger 6 
SETD1B                0.015   SET domain containing 1B 
CXXC5                 0.013   CXXC finger 5 
SRRM2                 0.013   splicing coactivator subunit SRm300 
MBD4                  0.012   methyl-CpG binding domain protein 4 
PRR12                 0.012   proline rich 12 
EP400                 0.012   E1A binding protein p400 
LOC646862             0.011   PREDICTED: hypothetical protein LOC646862 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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