Guide to the Human Genome
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Name: PITX2 Sequence: fasta or formatted (324aa) NCBI GI: 21361183
Description:

paired-like homeodomain transcription factor 2 isoform c

Referenced in:

Homeobox and Related Proteins
Left-Right Axis
Pituitary

Other entries for this name:
alt prot [317aa] paired-like homeodomain transcription factor 2 isoform b
alt prot [271aa] paired-like homeodomain transcription factor 2 isoform a
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.3         27           2
 C cysteine            1.9          6           1
 D aspartate           3.1         10           2
 E glutamate           4.0         13           2
 F phenylalanine       3.1         10           2
 G glycine             4.0         13           1
 H histidine           2.5          8           2
 I isoleucine          0.9          3           1
 K lysine              5.2         17           3
 L leucine             7.4         24           1
 M methionine          3.4         11           1
 N asparagine          7.1         23           2
 P proline             8.3         27           2
 Q glutamine           5.6         18           2
 R arginine            6.2         20           2
 S serine             15.1         49           4
 T threonine           4.6         15           1
 V valine              4.9         16           1
 W tryptophan          1.2          4           1
 Y tyrosine            3.1         10           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   paired-like homeodomain transcription factor 2 isofo... 
PITX2                 0.791   paired-like homeodomain transcription factor 2 isofo...
PITX2                 0.786   paired-like homeodomain transcription factor 2 isofo...
PITX1                 0.534   paired-like homeodomain transcription factor 1 [Hom...
PITX3                 0.428   paired-like homeodomain 3 
ALX1                  0.148   cartilage paired-class homeoprotein 1 
ALX4                  0.137   aristaless-like homeobox 4 
ARX                   0.131   aristaless related homeobox 
DRGX                  0.126   dorsal root ganglia homeobox 
PAX7                  0.124   paired box 7 isoform 3 
PAX7                  0.123   paired box 7 isoform 1 
PAX7                  0.123   paired box 7 isoform 2 
ALX3                  0.118   aristaless-like homeobox 3 
RAX                   0.118   retina and anterior neural fold homeobox 
PAX3                  0.112   paired box 3 isoform PAX3i 
PAX3                  0.112   paired box 3 isoform PAX3e 
PAX3                  0.112   paired box 3 isoform PAX3d 
PAX3                  0.112   paired box 3 isoform PAX3 
PAX3                  0.109   paired box 3 isoform PAX3g 
PAX3                  0.109   paired box 3 isoform PAX3h 
OTP                   0.107   PREDICTED: orthopedia homeobox 
DMBX1                 0.107   diencephalon/mesencephalon homeobox 1 isoform b [Hom...
OTP                   0.107   orthopedia homeobox 
DMBX1                 0.107   diencephalon/mesencephalon homeobox 1 isoform a [Hom...
PRRX1                 0.106   paired mesoderm homeobox 1 isoform pmx-1a 
PRRX1                 0.106   paired mesoderm homeobox 1 isoform pmx-1b 
VSX2                  0.102   visual system homeobox 2 
VSX1                  0.101   visual system homeobox 1 isoform a 
PHOX2B                0.099   paired-like homeobox 2b 
OTX1                  0.098   orthodenticle homeobox 1 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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