Guide to the Human Genome
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Name: PHOX2B Sequence: fasta or formatted (314aa) NCBI GI: 12707580
Description:

paired-like homeobox 2b

Referenced in:

Protein Composition and Structure
Homeobox and Related Proteins

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine            18.2         57          20
 C cysteine            1.6          5           1
 D aspartate           3.8         12           2
 E glutamate           4.1         13           2
 F phenylalanine       3.2         10           1
 G glycine            13.1         41           6
 H histidine           1.0          3           1
 I isoleucine          1.9          6           1
 K lysine              5.1         16           2
 L leucine             5.4         17           1
 M methionine          1.6          5           1
 N asparagine          2.9          9           1
 P proline             8.0         25           1
 Q glutamine           3.2         10           1
 R arginine            4.8         15           2
 S serine             11.1         35           2
 T threonine           5.4         17           2
 V valine              1.9          6           1
 W tryptophan          0.6          2           1
 Y tyrosine            3.2         10           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   paired-like homeobox 2b 
PHOX2A                0.419   paired-like homeobox 2a 
UNCX                  0.153   UNC homeobox 
OTX1                  0.150   orthodenticle homeobox 1 
ARX                   0.143   aristaless related homeobox 
CRX                   0.141   cone-rod homeobox protein 
DRGX                  0.140   dorsal root ganglia homeobox 
PRRX2                 0.137   paired related homeobox 2 
ALX3                  0.137   aristaless-like homeobox 3 
RAX                   0.135   retina and anterior neural fold homeobox 
ALX4                  0.135   aristaless-like homeobox 4 
PRRX1                 0.128   paired mesoderm homeobox 1 isoform pmx-1a 
PRRX1                 0.128   paired mesoderm homeobox 1 isoform pmx-1b 
PAX7                  0.127   paired box 7 isoform 1 
PAX7                  0.127   paired box 7 isoform 2 
PAX7                  0.127   paired box 7 isoform 3 
OTP                   0.127   PREDICTED: orthopedia homeobox 
RAX2                  0.127   retina and anterior neural fold homeobox 2 
OTP                   0.127   orthopedia homeobox 
ALX1                  0.127   cartilage paired-class homeoprotein 1 
PITX3                 0.125   paired-like homeodomain 3 
PAX3                  0.123   paired box 3 isoform PAX3i 
PAX3                  0.123   paired box 3 isoform PAX3g 
PAX3                  0.123   paired box 3 isoform PAX3h 
PAX3                  0.123   paired box 3 isoform PAX3e 
PAX3                  0.123   paired box 3 isoform PAX3d 
PAX3                  0.123   paired box 3 isoform PAX3 
VSX2                  0.118   visual system homeobox 2 
VSX1                  0.118   visual system homeobox 1 isoform a 
DMBX1                 0.117   diencephalon/mesencephalon homeobox 1 isoform b [Hom...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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