Guide to the Human Genome
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Search of human proteins with 205277451

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|205277451 single Ig IL-1R-related molecule [Homo sapiens]
         (410 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|205277451 single Ig IL-1R-related molecule [Homo sapiens]          831   0.0  
gi|205277449 single Ig IL-1R-related molecule [Homo sapiens]          831   0.0  
gi|205277445 single Ig IL-1R-related molecule [Homo sapiens]          831   0.0  
gi|239749936 PREDICTED: similar to single Ig IL-1R-related molec...   413   e-115
gi|11225607 interleukin 1 receptor accessory protein-like 2 [Hom...    96   6e-20
gi|7657232 interleukin 1 receptor accessory protein-like 1 precu...    89   6e-18
gi|4504661 interleukin 1 receptor accessory protein isoform 1 [H...    85   1e-16
gi|4504655 interleukin 18 receptor 1 precursor [Homo sapiens]          79   1e-14
gi|27894324 interleukin 1 receptor-like 1 isoform 1 precursor [H...    70   3e-12
gi|28416902 interleukin 1 receptor-like 2 precursor [Homo sapiens]     69   8e-12
gi|4504659 interleukin 1 receptor, type I precursor [Homo sapiens]     69   1e-11
gi|4504657 interleukin 18 receptor accessory protein precursor [...    68   1e-11
gi|19718734 toll-like receptor 2 [Homo sapiens]                        47   4e-05
gi|197276654 myeloid differentiation primary response gene 88 [H...    45   2e-04
gi|19924149 toll-like receptor 4 precursor [Homo sapiens]              44   3e-04
gi|148886752 immunoglobulin superfamily, member 9B [Homo sapiens]      39   0.009
gi|4503173 coxsackie virus and adenovirus receptor precursor [Ho...    38   0.015
gi|20143971 toll-like receptor 6 [Homo sapiens]                        37   0.025
gi|41350337 toll-like receptor 1 [Homo sapiens]                        37   0.025
gi|16751843 toll-like receptor 5 [Homo sapiens]                        37   0.032
gi|62865621 toll-like receptor 10 precursor [Homo sapiens]             35   0.12 
gi|62865618 toll-like receptor 10 precursor [Homo sapiens]             35   0.12 
gi|58331253 obscurin, cytoskeletal calmodulin and titin-interact...    35   0.12 
gi|148833506 obscurin, cytoskeletal calmodulin and titin-interac...    35   0.12 
gi|61742797 basal cell adhesion molecule isoform 2 precursor [Ho...    34   0.27 
gi|31543106 basal cell adhesion molecule isoform 1 precursor [Ho...    34   0.27 
gi|118572606 hemicentin 1 [Homo sapiens]                               34   0.27 
gi|134244585 putative neuronal cell adhesion molecule [Homo sapi...    34   0.27 
gi|110349719 titin isoform N2-A [Homo sapiens]                         33   0.61 
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]                    32   1.0  

>gi|205277451 single Ig IL-1R-related molecule [Homo sapiens]
          Length = 410

 Score =  831 bits (2147), Expect = 0.0
 Identities = 410/410 (100%), Positives = 410/410 (100%)

Query: 1   MPGVCDRAPDFLSPSEDQVLRPALGSSVALNCTAWVVSGPHCSLPSVQWLKDGLPLGIGG 60
           MPGVCDRAPDFLSPSEDQVLRPALGSSVALNCTAWVVSGPHCSLPSVQWLKDGLPLGIGG
Sbjct: 1   MPGVCDRAPDFLSPSEDQVLRPALGSSVALNCTAWVVSGPHCSLPSVQWLKDGLPLGIGG 60

Query: 61  HYSLHEYSWVKANLSEVLVSSVLGVNVTSTEVYGAFTCSIQNISFSSFTLQRAGPTSHVA 120
           HYSLHEYSWVKANLSEVLVSSVLGVNVTSTEVYGAFTCSIQNISFSSFTLQRAGPTSHVA
Sbjct: 61  HYSLHEYSWVKANLSEVLVSSVLGVNVTSTEVYGAFTCSIQNISFSSFTLQRAGPTSHVA 120

Query: 121 AVLASLLVLLALLLAALLYVKCRLNVLLWYQDAYGEVEINDGKLYDAYVSYSDCPEDRKF 180
           AVLASLLVLLALLLAALLYVKCRLNVLLWYQDAYGEVEINDGKLYDAYVSYSDCPEDRKF
Sbjct: 121 AVLASLLVLLALLLAALLYVKCRLNVLLWYQDAYGEVEINDGKLYDAYVSYSDCPEDRKF 180

Query: 181 VNFILKPQLERRRGYKLFLDDRDLLPRAEPSADLLVNLSRCRRLIVVLSDAFLSRAWCSH 240
           VNFILKPQLERRRGYKLFLDDRDLLPRAEPSADLLVNLSRCRRLIVVLSDAFLSRAWCSH
Sbjct: 181 VNFILKPQLERRRGYKLFLDDRDLLPRAEPSADLLVNLSRCRRLIVVLSDAFLSRAWCSH 240

Query: 241 SFREGLCRLLELTRRPIFITFEGQRRDPAHPALRLLRQHRHLVTLLLWRPGSVTPSSDFW 300
           SFREGLCRLLELTRRPIFITFEGQRRDPAHPALRLLRQHRHLVTLLLWRPGSVTPSSDFW
Sbjct: 241 SFREGLCRLLELTRRPIFITFEGQRRDPAHPALRLLRQHRHLVTLLLWRPGSVTPSSDFW 300

Query: 301 KEVQLALPRKVQYRPVEGDPQTQLQDDKDPMLILRGRVPEGRALDSEVDPDPEGDLGVRG 360
           KEVQLALPRKVQYRPVEGDPQTQLQDDKDPMLILRGRVPEGRALDSEVDPDPEGDLGVRG
Sbjct: 301 KEVQLALPRKVQYRPVEGDPQTQLQDDKDPMLILRGRVPEGRALDSEVDPDPEGDLGVRG 360

Query: 361 PVFGEPSAPPHTSGVSLGESRSSEVDVSDLGSRNYSARTDFYCLVSKDDM 410
           PVFGEPSAPPHTSGVSLGESRSSEVDVSDLGSRNYSARTDFYCLVSKDDM
Sbjct: 361 PVFGEPSAPPHTSGVSLGESRSSEVDVSDLGSRNYSARTDFYCLVSKDDM 410


>gi|205277449 single Ig IL-1R-related molecule [Homo sapiens]
          Length = 410

 Score =  831 bits (2147), Expect = 0.0
 Identities = 410/410 (100%), Positives = 410/410 (100%)

Query: 1   MPGVCDRAPDFLSPSEDQVLRPALGSSVALNCTAWVVSGPHCSLPSVQWLKDGLPLGIGG 60
           MPGVCDRAPDFLSPSEDQVLRPALGSSVALNCTAWVVSGPHCSLPSVQWLKDGLPLGIGG
Sbjct: 1   MPGVCDRAPDFLSPSEDQVLRPALGSSVALNCTAWVVSGPHCSLPSVQWLKDGLPLGIGG 60

Query: 61  HYSLHEYSWVKANLSEVLVSSVLGVNVTSTEVYGAFTCSIQNISFSSFTLQRAGPTSHVA 120
           HYSLHEYSWVKANLSEVLVSSVLGVNVTSTEVYGAFTCSIQNISFSSFTLQRAGPTSHVA
Sbjct: 61  HYSLHEYSWVKANLSEVLVSSVLGVNVTSTEVYGAFTCSIQNISFSSFTLQRAGPTSHVA 120

Query: 121 AVLASLLVLLALLLAALLYVKCRLNVLLWYQDAYGEVEINDGKLYDAYVSYSDCPEDRKF 180
           AVLASLLVLLALLLAALLYVKCRLNVLLWYQDAYGEVEINDGKLYDAYVSYSDCPEDRKF
Sbjct: 121 AVLASLLVLLALLLAALLYVKCRLNVLLWYQDAYGEVEINDGKLYDAYVSYSDCPEDRKF 180

Query: 181 VNFILKPQLERRRGYKLFLDDRDLLPRAEPSADLLVNLSRCRRLIVVLSDAFLSRAWCSH 240
           VNFILKPQLERRRGYKLFLDDRDLLPRAEPSADLLVNLSRCRRLIVVLSDAFLSRAWCSH
Sbjct: 181 VNFILKPQLERRRGYKLFLDDRDLLPRAEPSADLLVNLSRCRRLIVVLSDAFLSRAWCSH 240

Query: 241 SFREGLCRLLELTRRPIFITFEGQRRDPAHPALRLLRQHRHLVTLLLWRPGSVTPSSDFW 300
           SFREGLCRLLELTRRPIFITFEGQRRDPAHPALRLLRQHRHLVTLLLWRPGSVTPSSDFW
Sbjct: 241 SFREGLCRLLELTRRPIFITFEGQRRDPAHPALRLLRQHRHLVTLLLWRPGSVTPSSDFW 300

Query: 301 KEVQLALPRKVQYRPVEGDPQTQLQDDKDPMLILRGRVPEGRALDSEVDPDPEGDLGVRG 360
           KEVQLALPRKVQYRPVEGDPQTQLQDDKDPMLILRGRVPEGRALDSEVDPDPEGDLGVRG
Sbjct: 301 KEVQLALPRKVQYRPVEGDPQTQLQDDKDPMLILRGRVPEGRALDSEVDPDPEGDLGVRG 360

Query: 361 PVFGEPSAPPHTSGVSLGESRSSEVDVSDLGSRNYSARTDFYCLVSKDDM 410
           PVFGEPSAPPHTSGVSLGESRSSEVDVSDLGSRNYSARTDFYCLVSKDDM
Sbjct: 361 PVFGEPSAPPHTSGVSLGESRSSEVDVSDLGSRNYSARTDFYCLVSKDDM 410


>gi|205277445 single Ig IL-1R-related molecule [Homo sapiens]
          Length = 410

 Score =  831 bits (2147), Expect = 0.0
 Identities = 410/410 (100%), Positives = 410/410 (100%)

Query: 1   MPGVCDRAPDFLSPSEDQVLRPALGSSVALNCTAWVVSGPHCSLPSVQWLKDGLPLGIGG 60
           MPGVCDRAPDFLSPSEDQVLRPALGSSVALNCTAWVVSGPHCSLPSVQWLKDGLPLGIGG
Sbjct: 1   MPGVCDRAPDFLSPSEDQVLRPALGSSVALNCTAWVVSGPHCSLPSVQWLKDGLPLGIGG 60

Query: 61  HYSLHEYSWVKANLSEVLVSSVLGVNVTSTEVYGAFTCSIQNISFSSFTLQRAGPTSHVA 120
           HYSLHEYSWVKANLSEVLVSSVLGVNVTSTEVYGAFTCSIQNISFSSFTLQRAGPTSHVA
Sbjct: 61  HYSLHEYSWVKANLSEVLVSSVLGVNVTSTEVYGAFTCSIQNISFSSFTLQRAGPTSHVA 120

Query: 121 AVLASLLVLLALLLAALLYVKCRLNVLLWYQDAYGEVEINDGKLYDAYVSYSDCPEDRKF 180
           AVLASLLVLLALLLAALLYVKCRLNVLLWYQDAYGEVEINDGKLYDAYVSYSDCPEDRKF
Sbjct: 121 AVLASLLVLLALLLAALLYVKCRLNVLLWYQDAYGEVEINDGKLYDAYVSYSDCPEDRKF 180

Query: 181 VNFILKPQLERRRGYKLFLDDRDLLPRAEPSADLLVNLSRCRRLIVVLSDAFLSRAWCSH 240
           VNFILKPQLERRRGYKLFLDDRDLLPRAEPSADLLVNLSRCRRLIVVLSDAFLSRAWCSH
Sbjct: 181 VNFILKPQLERRRGYKLFLDDRDLLPRAEPSADLLVNLSRCRRLIVVLSDAFLSRAWCSH 240

Query: 241 SFREGLCRLLELTRRPIFITFEGQRRDPAHPALRLLRQHRHLVTLLLWRPGSVTPSSDFW 300
           SFREGLCRLLELTRRPIFITFEGQRRDPAHPALRLLRQHRHLVTLLLWRPGSVTPSSDFW
Sbjct: 241 SFREGLCRLLELTRRPIFITFEGQRRDPAHPALRLLRQHRHLVTLLLWRPGSVTPSSDFW 300

Query: 301 KEVQLALPRKVQYRPVEGDPQTQLQDDKDPMLILRGRVPEGRALDSEVDPDPEGDLGVRG 360
           KEVQLALPRKVQYRPVEGDPQTQLQDDKDPMLILRGRVPEGRALDSEVDPDPEGDLGVRG
Sbjct: 301 KEVQLALPRKVQYRPVEGDPQTQLQDDKDPMLILRGRVPEGRALDSEVDPDPEGDLGVRG 360

Query: 361 PVFGEPSAPPHTSGVSLGESRSSEVDVSDLGSRNYSARTDFYCLVSKDDM 410
           PVFGEPSAPPHTSGVSLGESRSSEVDVSDLGSRNYSARTDFYCLVSKDDM
Sbjct: 361 PVFGEPSAPPHTSGVSLGESRSSEVDVSDLGSRNYSARTDFYCLVSKDDM 410


>gi|239749936 PREDICTED: similar to single Ig IL-1R-related molecule
           [Homo sapiens]
          Length = 304

 Score =  413 bits (1062), Expect = e-115
 Identities = 202/202 (100%), Positives = 202/202 (100%)

Query: 209 EPSADLLVNLSRCRRLIVVLSDAFLSRAWCSHSFREGLCRLLELTRRPIFITFEGQRRDP 268
           EPSADLLVNLSRCRRLIVVLSDAFLSRAWCSHSFREGLCRLLELTRRPIFITFEGQRRDP
Sbjct: 103 EPSADLLVNLSRCRRLIVVLSDAFLSRAWCSHSFREGLCRLLELTRRPIFITFEGQRRDP 162

Query: 269 AHPALRLLRQHRHLVTLLLWRPGSVTPSSDFWKEVQLALPRKVQYRPVEGDPQTQLQDDK 328
           AHPALRLLRQHRHLVTLLLWRPGSVTPSSDFWKEVQLALPRKVQYRPVEGDPQTQLQDDK
Sbjct: 163 AHPALRLLRQHRHLVTLLLWRPGSVTPSSDFWKEVQLALPRKVQYRPVEGDPQTQLQDDK 222

Query: 329 DPMLILRGRVPEGRALDSEVDPDPEGDLGVRGPVFGEPSAPPHTSGVSLGESRSSEVDVS 388
           DPMLILRGRVPEGRALDSEVDPDPEGDLGVRGPVFGEPSAPPHTSGVSLGESRSSEVDVS
Sbjct: 223 DPMLILRGRVPEGRALDSEVDPDPEGDLGVRGPVFGEPSAPPHTSGVSLGESRSSEVDVS 282

Query: 389 DLGSRNYSARTDFYCLVSKDDM 410
           DLGSRNYSARTDFYCLVSKDDM
Sbjct: 283 DLGSRNYSARTDFYCLVSKDDM 304


>gi|11225607 interleukin 1 receptor accessory protein-like 2 [Homo
           sapiens]
          Length = 686

 Score = 95.9 bits (237), Expect = 6e-20
 Identities = 91/325 (28%), Positives = 148/325 (45%), Gaps = 22/325 (6%)

Query: 6   DRAPDFLSPSEDQ--VLRPALGSSVALNCTAWV-VSGPHCSLPSVQWLK-DGLPLGIGGH 61
           D+ P  L P E+Q  V+   LG  + + C A+   SG   S P + W+K +     + GH
Sbjct: 237 DKPPKPLFPMENQPSVIDVQLGKPLNIPCKAFFGFSGE--SGPMIYWMKGEKFIEELAGH 294

Query: 62  YSLHEYSWVKANLSEVLVSSVLGVNVTSTEVYGAFTCSIQNIS---FSSFTLQRAGPTSH 118
               E   +K +L E  V   L  +         +TC ++N +    +S  L++      
Sbjct: 295 IREGEIRLLKEHLGEKEVELALIFDSVVEADLANYTCHVENRNGRKHASVLLRKKDLIYK 354

Query: 119 VAAVLASLLVLLALLLAALLYVKCRLNVLLWYQDAYGEVEIND-GKLYDAYVSYS----- 172
           +        + L L+L  ++Y    + ++L+Y+  +G  E ND  K YDAY+SY+     
Sbjct: 355 IELAGGLGAIFLLLVLLVVIYKCYNIELMLFYRQHFGADETNDDNKEYDAYLSYTKVDQD 414

Query: 173 --DC--PEDRKFVNFILKPQLERRRGYKLFLDDRDLLPRAEPSADLLVNLSRCRRLIVVL 228
             DC  PE+ +F   +L   LE+  GYKLF+ +RDL+P      DL   + + RRLI+VL
Sbjct: 415 TLDCDNPEEEQFALEVLPDVLEKHYGYKLFIPERDLIPSGTYMEDLTRYVEQSRRLIIVL 474

Query: 229 S-DAFLSRAWCSHSFREGLCRLLELTR-RPIFITFEGQRRDPAHPALRLLRQHRHLVTLL 286
           + D  L R W        L  +L     + I I     +       +  L++   L++L+
Sbjct: 475 TPDYILRRGWSIFELESRLHNMLVSGEIKVILIECTELKGKVNCQEVESLKRSIKLLSLI 534

Query: 287 LWRPG-SVTPSSDFWKEVQLALPRK 310
            W+   S   +S FWK +   +P K
Sbjct: 535 KWKGSKSSKLNSKFWKHLVYEMPIK 559


>gi|7657232 interleukin 1 receptor accessory protein-like 1
           precursor [Homo sapiens]
          Length = 696

 Score = 89.4 bits (220), Expect = 6e-18
 Identities = 88/327 (26%), Positives = 150/327 (45%), Gaps = 25/327 (7%)

Query: 6   DRAPDFLSPSEDQ--VLRPALGSSVALNCTAWVVSGPHCSLPSVQWLKDGLPLGIGGHYS 63
           D+ P  L P E +  +    LG S  L C A+       S P + W+K    +       
Sbjct: 239 DKPPKLLYPMESKLTIQETQLGDSANLTCRAFFGYSGDVS-PLIYWMKGEKFIEDLDENR 297

Query: 64  LHEYSW--VKANLSEVLVSSVLGVNVTSTEVYGAFTCSIQNIS---FSSFTLQRAGP--T 116
           + E     +K +L E  VS  L V+       G ++C ++N +    +S  L +     T
Sbjct: 298 VWESDIRILKEHLGEQEVSISLIVDSVEEGDLGNYSCYVENGNGRRHASVLLHKRELMYT 357

Query: 117 SHVAAVLASLLVLLALLLAALLYVKCRLNVLLWYQDAYGEVEIN-DGKLYDAYVSYS--- 172
             +A  L ++L+LL  L+   +Y   ++ ++L+Y++ +G  E++ D K YDAY+SY+   
Sbjct: 358 VELAGGLGAILLLLVCLVT--IYKCYKIEIMLFYRNHFGAEELDGDNKDYDAYLSYTKVD 415

Query: 173 ------DCPEDRKFVNFILKPQLERRRGYKLFLDDRDLLPRAEPSADLLVNLSRCRRLIV 226
                 +  E+ +F   IL   LE+  GYKLF+ DRDL+P      D+   + + +RLI+
Sbjct: 416 PDQWNQETGEEERFALEILPDMLEKHYGYKLFIPDRDLIPTGTYIEDVARCVDQSKRLII 475

Query: 227 VLSDAF-LSRAWCSHSFREGLCRLLELTR-RPIFITFEGQRRDPAHPALRLLRQHRHLVT 284
           V++  + + R W        L  +L     + I I     R    +  +  L+    L+T
Sbjct: 476 VMTPNYVVRRGWSIFELETRLRNMLVTGEIKVILIECSELRGIMNYQEVEALKHTIKLLT 535

Query: 285 LLLWR-PGSVTPSSDFWKEVQLALPRK 310
           ++ W  P     +S FWK +Q  +P K
Sbjct: 536 VIKWHGPKCNKLNSKFWKRLQYEMPFK 562


>gi|4504661 interleukin 1 receptor accessory protein isoform 1 [Homo
           sapiens]
          Length = 570

 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 87/323 (26%), Positives = 150/323 (46%), Gaps = 15/323 (4%)

Query: 9   PDFLSPSEDQVLRPALGSSVALNCTAWVVSGPHCSLPSVQWLKDGL-PLGIGGHYSLHEY 67
           P   SP++  V     G  + + CT +  S    S   V W  DG  P  I    +++E 
Sbjct: 243 PVIHSPNDHVVYEKEPGEELLIPCTVYF-SFLMDSRNEVWWTIDGKKPDDITIDVTINE- 300

Query: 68  SWVKANLSEVLVSSVLGVN-VTSTEVYGAFTCSIQNIS---FSSFTLQRAGPTSHVAAVL 123
           S   +   +   + +L +  VTS ++  ++ C  ++       +  +++  P       L
Sbjct: 301 SISHSRTEDETRTQILSIKKVTSEDLKRSYVCHARSAKGEVAKAAKVKQKVPAPRYTVEL 360

Query: 124 A---SLLVLLALLLAALLYVKCRLNVLLWYQDAYGEVE-INDGKLYDAYVSYSDCPEDRK 179
           A      VLL ++L  + +V   L ++L+Y+  +G  E I DGK YD YVSY+   E+ +
Sbjct: 361 ACGFGATVLLVVILIVVYHVYW-LEMVLFYRAHFGTDETILDGKEYDIYVSYARNAEEEE 419

Query: 180 FVNFILKPQLERRRGYKLFLDDRDLLPRAEPSADLLVNLSRCRRLIVVLSDAFLSRAWCS 239
           FV   L+  LE   GYKL + DRD LP    + + L  + + RRL+VVLS  ++ +   +
Sbjct: 420 FVLLTLRGVLENEFGYKLCIFDRDSLPGGIVTDETLSFIQKSRRLLVVLSPNYVLQG--T 477

Query: 240 HSFREGLCRLLELTRRPIFITFEGQRRDPAHPALRLLRQHRHLVTLLLWR-PGSVTPSSD 298
            +  E    L  +  R        Q +      ++ L++ + ++T++ W+   S  P   
Sbjct: 478 QALLELKAGLENMASRGNINVILVQYKAVKETKVKELKRAKTVLTVIKWKGEKSKYPQGR 537

Query: 299 FWKEVQLALPRKVQYRPVEGDPQ 321
           FWK++Q+A+P K   R    D Q
Sbjct: 538 FWKQLQVAMPVKKSPRRSSSDEQ 560


>gi|4504655 interleukin 18 receptor 1 precursor [Homo sapiens]
          Length = 541

 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 90/337 (26%), Positives = 155/337 (45%), Gaps = 42/337 (12%)

Query: 9   PDFLSPSEDQVLRPALGSSVALNCTA---------WVVSGPHCSLPSVQWLKDGLPLGIG 59
           P  L P  + V    LG +V LNC+A         W+    + S P++   K+   +   
Sbjct: 215 PVLLGPKLNHVA-VELGKNVRLNCSALLNEEDVIYWMFGEENGSDPNIHEEKEMRIMTPE 273

Query: 60  GHYSLHEYSWVKANLSEVLVSSVLGVNVTSTEVYGAFTCSIQNISFSSFTLQRAGPTSHV 119
           G          K + S+VL    +G +  +  +Y     S       SF L R    + +
Sbjct: 274 G----------KWHASKVLRIENIGESNLNV-LYNCTVASTGGTDTKSFILVRKADMADI 322

Query: 120 AA------VLASLLVLLALLLAALLYVKCRLNVLLWYQDAYGEVE-INDGKLYDAYVSY- 171
                   ++ ++L+L+A++    + V  R++++L+Y+      E + DGK YDA+VSY 
Sbjct: 323 PGHVFTRGMIIAVLILVAVVCLVTVCVIYRVDLVLFYRHLTRRDETLTDGKTYDAFVSYL 382

Query: 172 SDCP----EDRKFVNFILKPQLERRRGYKLFLDDRDLLPRAEPSADLLVNLSRCRRLIVV 227
            +C     E+  F   IL   LE+  GYKL + +RD++P      ++   + + RRLI+V
Sbjct: 383 KECRPENGEEHTFAVEILPRVLEKHFGYKLCIFERDVVPGGAVVDEIHSLIEKSRRLIIV 442

Query: 228 LSDAFLSRAWCSHSFREGLCR-LLELTRRPIFITFEGQRRDPAHP-ALRLLRQHRHLVTL 285
           LS +++S     +    GL   L+E   + I I F         P +L+LL+ HR    +
Sbjct: 443 LSKSYMSNE-VRYELESGLHEALVERKIKIILIEFTPVTDFTFLPQSLKLLKSHR----V 497

Query: 286 LLWRPG-SVTPSSDFWKEVQLALPRKVQYRPVEGDPQ 321
           L W+   S++ +S FWK +   +P K   +P   +P+
Sbjct: 498 LKWKADKSLSYNSRFWKNLLYLMPAKT-VKPGRDEPE 533


>gi|27894324 interleukin 1 receptor-like 1 isoform 1 precursor [Homo
           sapiens]
          Length = 556

 Score = 70.1 bits (170), Expect = 3e-12
 Identities = 77/326 (23%), Positives = 131/326 (40%), Gaps = 35/326 (10%)

Query: 13  SPSEDQVLRPALGSSVALNCTAWVVSGPHCSLPSVQWLKDGLPLGIGGHYSLHEYSWVKA 72
           +P+++++    +G +  L C+A    G    L +V W  +G  +   G   + +      
Sbjct: 216 APAQNEIKEVEIGKNANLTCSACFGKGTQF-LAAVLWQLNGTKITDFGEPRIQQEEGQNQ 274

Query: 73  NLSEVLVSSVLGVNVTSTEV------YGAFTCSIQNISFSSFTLQRAGPTSH-----VAA 121
           + S  L    + + +   +       Y     ++  +   +  L R  P  H     + A
Sbjct: 275 SFSNGLACLDMVLRIADVKEEDLLLQYDCLALNLHGLRRHTVRLSRKNPIDHHSIYCIIA 334

Query: 122 VLASLLVLLALLLAALLYVKCRLNVLLWYQDAYGEVEINDGKLYDAYVSYSDCPEDRK-- 179
           V +  L+L+ +L+  L         LLW   A      NDGKLYDAYV Y   P + K  
Sbjct: 335 VCSVFLMLINVLVIILKMFWIEAT-LLWRDIAKPYKTRNDGKLYDAYVVY---PRNYKSS 390

Query: 180 ---------FVNFILKPQLERRRGYKLFLDDRDLLPRAEPSADLLVNLSRCRRLIVVLSD 230
                    FV+ IL   LE + GY L +  RD+LP  +    +  N+ + RR I +L+ 
Sbjct: 391 TDGASRVEHFVHQILPDVLENKCGYTLCIYGRDMLPGEDVVTAVETNIRKSRRHIFILTP 450

Query: 231 AFLSRAWCSHSFREGL-CRLLELTRRPIFITFEGQRRDPAHPALRLLRQHRHLVTL---L 286
                   ++     L C L++   + I I  E         A  L    +HL+ +   +
Sbjct: 451 QITHNKEFAYEQEVALHCALIQNDAKVILIEMEALSELDMLQAEALQDSLQHLMKVQGTI 510

Query: 287 LWRPGSV----TPSSDFWKEVQLALP 308
            WR   +    + +S FWK V+  +P
Sbjct: 511 KWREDHIANKRSLNSKFWKHVRYQMP 536


>gi|28416902 interleukin 1 receptor-like 2 precursor [Homo sapiens]
          Length = 575

 Score = 68.9 bits (167), Expect = 8e-12
 Identities = 53/156 (33%), Positives = 82/156 (52%), Gaps = 13/156 (8%)

Query: 85  VNVTSTEV----YGAFTCSIQNISFSSFTLQRAGPTSHVAAVLASLLVLLALLLAAL-LY 139
           VN+T  EV    YG        +S +   LQ   P    A ++  L+ L+A+ ++ + +Y
Sbjct: 298 VNITFLEVKMEDYGLPFMCHAGVSTAYIILQLPAPDFR-AYLIGGLIALVAVAVSVVYIY 356

Query: 140 VKCRLNVLLWYQDAYGEVE-INDGKLYDAYVSYSDCPEDRK------FVNFILKPQLERR 192
              +++++LWY+ A+   E I DGKLYDAYV Y    ++ +       V  IL   LER+
Sbjct: 357 NIFKIDIVLWYRSAFHSTETIVDGKLYDAYVLYPKPHKESQRHAVDALVLNILPEVLERQ 416

Query: 193 RGYKLFLDDRDLLPRAEPSADLLVNLSRCRRLIVVL 228
            GYKLF+  RD  P    +  +  N+  CRRLIV++
Sbjct: 417 CGYKLFIFGRDEFPGQAVANVIDENVKLCRRLIVIV 452


>gi|4504659 interleukin 1 receptor, type I precursor [Homo sapiens]
          Length = 569

 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 75/325 (23%), Positives = 145/325 (44%), Gaps = 36/325 (11%)

Query: 9   PDFLSPSEDQVLRPALGSSVALNCTAWVVSGPHCSLPSVQW----LKDGLPLGIGGHYSL 64
           P  +SP+ ++ +   LGS + L C    V+G    +   +W    + +  P+    +YS+
Sbjct: 226 PVIVSPA-NETMEVDLGSQIQLICN---VTGQLSDIAYWKWNGSVIDEDDPVLGEDYYSV 281

Query: 65  HEYSWVKANLSEVLVSSVLGVNVTSTEVYG-AFTCSIQNI-SFSSFTLQRAGPTSHVAAV 122
                  AN     + +VL ++   +  Y   FTC  +N     +  +Q   P ++    
Sbjct: 282 EN----PANKRRSTLITVLNISEIESRFYKHPFTCFAKNTHGIDAAYIQLIYPVTNFQKH 337

Query: 123 LASLLVLLALLL--AALLYVKCRLNVLLWYQDA---YGEVEINDGKLYDAYVSY------ 171
           +  + V L +++  +  +Y   +++++LWY+D+   +  ++ +DGK YDAY+ Y      
Sbjct: 338 MIGICVTLTVIIVCSVFIYKIFKIDIVLWYRDSCYDFLPIKASDGKTYDAYILYPKTVGE 397

Query: 172 ---SDCPEDRKFVNFILKPQLERRRGYKLFLDDRDLLPRAEPSADLLVNLSRCRRLIVVL 228
              SDC     FV  +L   LE++ GYKLF+  RD     +    +  N+ + RRLI++L
Sbjct: 398 GSTSDCDI---FVFKVLPEVLEKQCGYKLFIYGRDDYVGEDIVEVINENVKKSRRLIIIL 454

Query: 229 SDAFLSRAWCSHSFREGLCRLLELTRRPIFITF----EGQRRDPAHPALRLLRQ-HRHLV 283
                  +W   S  E +     L +  I +      + Q  +    +++ ++Q H  + 
Sbjct: 455 VRETSGFSWLGGSSEEQIAMYNALVQDGIKVVLLELEKIQDYEKMPESIKFIKQKHGAIR 514

Query: 284 TLLLWRPGSVTPSSDFWKEVQLALP 308
               +  G  +  + FWK V+  +P
Sbjct: 515 WSGDFTQGPQSAKTRFWKNVRYHMP 539


>gi|4504657 interleukin 18 receptor accessory protein precursor
           [Homo sapiens]
          Length = 599

 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 80/319 (25%), Positives = 146/319 (45%), Gaps = 24/319 (7%)

Query: 9   PDFLSPSEDQVLRPALGSSVALNCTAWVVSGPHCSLPSVQW-LKDGLPLGIGGHYSLHEY 67
           PD L P ED  L   LG  + ++C A          P ++W +KD     +    S+ E 
Sbjct: 251 PDILDPVED-TLEVELGKPLTISCKARF-GFERVFNPVIKWYIKDS---DLEWEVSVPEA 305

Query: 68  SWVKANLS-EVLVSSVLGVNVTSTEVYGAFTCSIQNI---SFSSFTLQRAGPTSHVAAVL 123
             +K+ L  E++  +++   VT  ++   F C +QN    +  S  L+       +  +L
Sbjct: 306 KSIKSTLKDEIIERNIILEKVTQRDLRRKFVCFVQNSIGNTTQSVQLKEKRGVVLLYILL 365

Query: 124 ASLLVLLALLLAALLYVKCRLNVLLWYQDAYGEVE-INDGKLYDAYVSY---SDCPED-- 177
            ++  L+A+L A+ L  +  + ++L Y+    + + + D K +DA+VSY   S  P +  
Sbjct: 366 GTIGTLVAVLAASALLYRHWIEIVLLYRTYQSKDQTLGDKKDFDAFVSYAKWSSFPSEAT 425

Query: 178 ----RKFVNFILKPQ-LERRRGYKLFLDDRDLLPRAEPSADLLVNLSRCRRLIVVLSDAF 232
                + +   L P  LE + GY L L +RD+ P    + D++  + R RR I +LS  +
Sbjct: 426 SSLSEEHLALSLFPDVLENKYGYSLCLLERDVAPGGVYAEDIVSIIKRSRRGIFILSPNY 485

Query: 233 LSRAWCSHSFREGLCRLLELTRRPIFITFEGQRRDPAHPALRLLRQHRHLVTLLLWRP-G 291
           ++              L + T + I I F   +   + P   L+++   ++  + WR   
Sbjct: 486 VNGPSIFELQAAVNLALDDQTLKLILIKFCYFQEPESLP--HLVKKALRVLPTVTWRGLK 543

Query: 292 SVTPSSDFWKEVQLALPRK 310
           SV P+S FW +++  +P K
Sbjct: 544 SVPPNSRFWAKMRYHMPVK 562


>gi|19718734 toll-like receptor 2 [Homo sapiens]
          Length = 784

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 51/201 (25%), Positives = 84/201 (41%), Gaps = 15/201 (7%)

Query: 118 HVAAVLASLLVLLALLLAALLYVKCRLNVLLWYQD---AYGEVEINDGKL------YDAY 168
           H  A+++ +   L LL+  L  V C     LWY     A+ + +    K       YDA+
Sbjct: 586 HRTALVSGMCCALFLLIL-LTGVLCHRFHGLWYMKMMWAWLQAKRKPRKAPSRNICYDAF 644

Query: 169 VSYSDCPEDRKFVNFILKPQLER-RRGYKLFLDDRDLLPRAEPSADLLVNLSRCRRLIVV 227
           VSYS+   D  +V  ++  +LE     +KL L  RD +P      +++ ++ +  + + V
Sbjct: 645 VSYSE--RDAYWVENLMVQELENFNPPFKLCLHKRDFIPGKWIIDNIIDSIEKSHKTVFV 702

Query: 228 LSDAFLSRAWCSHSFREGLCRLL-ELTRRPIFITFEGQRRDPAHPALRLLRQHRHLVTLL 286
           LS+ F+   WC +       RL  E     I I  E   +         LR+  +  T L
Sbjct: 703 LSENFVKSEWCKYELDFSHFRLFDENNDAAILILLEPIEKKAIPQRFCKLRKIMNTKTYL 762

Query: 287 LWRPGSVTPSSDFWKEVQLAL 307
            W P        FW  ++ A+
Sbjct: 763 EW-PMDEAQREGFWVNLRAAI 782


>gi|197276654 myeloid differentiation primary response gene 88 [Homo
           sapiens]
          Length = 309

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 26/77 (33%), Positives = 44/77 (57%), Gaps = 7/77 (9%)

Query: 165 YDAYVSYSDCPEDRKFVNFILKPQLERRRGYKLFLDDRDLLPRA---EPSADLLVNLSRC 221
           +DA++ Y  CP D +FV  +++   +     KL + DRD+LP       +++L+    RC
Sbjct: 174 FDAFICY--CPSDIQFVQEMIRQLEQTNYRLKLCVSDRDVLPGTCVWSIASELIE--KRC 229

Query: 222 RRLIVVLSDAFLSRAWC 238
           RR++VV+SD +L    C
Sbjct: 230 RRMVVVVSDDYLQSKEC 246


>gi|19924149 toll-like receptor 4 precursor [Homo sapiens]
          Length = 839

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 52/191 (27%), Positives = 86/191 (45%), Gaps = 20/191 (10%)

Query: 125 SLLVLLALLLAALLYVKCRLNVLLWYQDAYGEVEINDGK-LYDAYVSYSDCPEDRKFVNF 183
           S+L +L + + A+L  K   +++L      G ++   G+ +YDA+V YS   ED    N 
Sbjct: 637 SVLSVLVVSVVAVLVYKFYFHLML----LAGCIKYGRGENIYDAFVIYSSQDEDW-VRNE 691

Query: 184 ILKPQLERRRGYKLFLDDRDLLPRAEPSADLL-VNLSRCRRLIVVLSDAFLSRAWCSHSF 242
           ++K   E    ++L L  RD +P    +A+++     + R++IVV+S  F+   WC   +
Sbjct: 692 LVKNLEEGVPPFQLCLHYRDFIPGVAIAANIIHEGFHKSRKVIVVVSQHFIQSRWCIFEY 751

Query: 243 R-EGLCRLLELTRRPIFITFEGQRRDPAHPALRLLRQHRHLVTLL-----LWRPGSVTPS 296
                 + L      IFI  +   +        LLRQ   L  LL     L    SV   
Sbjct: 752 EIAQTWQFLSSRAGIIFIVLQKVEK-------TLLRQQVELYRLLSRNTYLEWEDSVLGR 804

Query: 297 SDFWKEVQLAL 307
             FW+ ++ AL
Sbjct: 805 HIFWRRLRKAL 815


>gi|148886752 immunoglobulin superfamily, member 9B [Homo sapiens]
          Length = 1349

 Score = 38.9 bits (89), Expect = 0.009
 Identities = 34/111 (30%), Positives = 46/111 (41%), Gaps = 22/111 (19%)

Query: 8   APDFLSPSEDQVLRPALGSSVALNCTAWVVSGPHCSLPSVQWLKDGLPLGIGGHYSLHEY 67
           AP   + +  Q +    G S+ + CTA+    P    P V WLK+G  LG  G Y + + 
Sbjct: 137 APPTFTETPPQYIEAKEGGSITMTCTAF--GNPK---PIVTWLKEGTLLGASGKYQVSDG 191

Query: 68  SWVKANLSEVLVSSVLGVNVTSTEVYGAFTC---SIQNISFSSFTLQRAGP 115
           S              L V   S E  GA+TC   SIQ  +  +  L   GP
Sbjct: 192 S--------------LTVTSVSREDRGAYTCRAYSIQGEAVHTTHLLVQGP 228


>gi|4503173 coxsackie virus and adenovirus receptor precursor [Homo
           sapiens]
          Length = 365

 Score = 38.1 bits (87), Expect = 0.015
 Identities = 28/90 (31%), Positives = 45/90 (50%), Gaps = 12/90 (13%)

Query: 66  EYSWVKANLSEVL--------VSSVLGVNVTSTEVYGAFTCSIQNISFSSFTLQRAG--P 115
           +Y W K + S+ +         SSV+ V   S+E  G ++C+++N   S   L R    P
Sbjct: 172 QYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNVVP 231

Query: 116 TSHVAAVLASLLV--LLALLLAALLYVKCR 143
            S+ A ++A  ++  LLAL L  L+   CR
Sbjct: 232 PSNKAGLIAGAIIGTLLALALIGLIIFCCR 261


>gi|20143971 toll-like receptor 6 [Homo sapiens]
          Length = 796

 Score = 37.4 bits (85), Expect = 0.025
 Identities = 38/162 (23%), Positives = 67/162 (41%), Gaps = 19/162 (11%)

Query: 158 EINDGKLYDAYVSYSDCPEDRKFVNFILKPQLERRRGYKLFLDDRDLLPRAEPSADLLVN 217
           E+     + A++SYS+   D  +V   L P LE+    ++ L +R+ +P      +++  
Sbjct: 635 ELQRNLQFHAFISYSE--HDSAWVKSELVPYLEKE-DIQICLHERNFVPGKSIVENIINC 691

Query: 218 LSRCRRLIVVLSDAFLSRAWCSHS--------FREGLCRLLELTRRPIFITFEGQRRDPA 269
           + +  + I VLS  F+   WC +         F EG   L+ +   PI    +    +  
Sbjct: 692 IEKSYKSIFVLSPNFVQSEWCHYELYFAHHNLFHEGSNNLILILLEPI---PQNSIPNKY 748

Query: 270 HPALRLLRQHRHLVTLLLWRPGSVTPSSDFWKEVQLALPRKV 311
           H    L+ Q     T L W P   +    FW  ++ A   K+
Sbjct: 749 HKLKALMTQR----TYLQW-PKEKSKRGLFWANIRAAFNMKL 785


>gi|41350337 toll-like receptor 1 [Homo sapiens]
          Length = 786

 Score = 37.4 bits (85), Expect = 0.025
 Identities = 28/108 (25%), Positives = 49/108 (45%), Gaps = 11/108 (10%)

Query: 158 EINDGKLYDAYVSYSDCPEDRKFVNFILKPQLERRRGYKLFLDDRDLLPRAEPSADLLVN 217
           E+     + A++SYS    D  +V   L P LE+  G ++ L +R+ +P      +++  
Sbjct: 630 ELQRNLQFHAFISYSG--HDSFWVKNELLPNLEKE-GMQICLHERNFVPGKSIVENIITC 686

Query: 218 LSRCRRLIVVLSDAFLSRAWCSHS--------FREGLCRLLELTRRPI 257
           + +  + I VLS  F+   WC +         F EG   L+ +   PI
Sbjct: 687 IEKSYKSIFVLSPNFVQSEWCHYELYFAHHNLFHEGSNSLILILLEPI 734


>gi|16751843 toll-like receptor 5 [Homo sapiens]
          Length = 858

 Score = 37.0 bits (84), Expect = 0.032
 Identities = 42/175 (24%), Positives = 78/175 (44%), Gaps = 20/175 (11%)

Query: 91  EVYGAFTCSIQNISFSSFTLQRAGPTSHVAAVLASLLVL----LALLLAALLYV-KCRLN 145
           ++Y  +  S   +S  S + +       + ++  SL ++    L L L  +L V K R  
Sbjct: 607 DIYCVYPDSFSGVSLFSLSTEGCDEEEVLKSLKFSLFIVCTVTLTLFLMTILTVTKFRGF 666

Query: 146 VLLWYQDAYGEVEIN-------DGKLYDAYVSYSDCPEDRKFV-NFILK---PQLERRRG 194
             + Y+ A   V  +       D   YDAY+ +S   +D  +V N +LK    Q   +  
Sbjct: 667 CFICYKTAQRLVFKDHPQGTEPDMYKYDAYLCFSS--KDFTWVQNALLKHLDTQYSDQNR 724

Query: 195 YKLFLDDRDLLPRAEPSADLLVNLSRCRRLIVVLSDAFLSRAWC--SHSFREGLC 247
           + L  ++RD +P     A++   +   R+++ ++S  FL   WC  + S+ +G C
Sbjct: 725 FNLCFEERDFVPGENRIANIQDAIWNSRKIVCLVSRHFLRDGWCLEAFSYAQGRC 779


>gi|62865621 toll-like receptor 10 precursor [Homo sapiens]
          Length = 811

 Score = 35.0 bits (79), Expect = 0.12
 Identities = 33/136 (24%), Positives = 57/136 (41%), Gaps = 16/136 (11%)

Query: 121 AVLASLLVLLALLLAALLYVKCRLNVLLWYQDAYGEV-------------EINDGKLYDA 167
           A+L   +V++ L+L   +   C    L WY    G+              ++     + A
Sbjct: 577 ALLIVTIVVIMLVLGLAVAFCCLHFDLPWYLRMLGQCTQTWHRVRKTTQEQLKRNVRFHA 636

Query: 168 YVSYSDCPEDRKFVNFILKPQLERRRGYKLF-LDDRDLLPRAEPSADLLVNLSRCRRLIV 226
           ++SYS+   D  +V   L P LE+  G  L  L +    P    S +++  + +  + I 
Sbjct: 637 FISYSE--HDSLWVKNELIPNLEKEDGSILICLYESYFDPGKSISENIVSFIEKSYKSIF 694

Query: 227 VLSDAFLSRAWCSHSF 242
           VLS  F+   WC + F
Sbjct: 695 VLSPNFVQNEWCHYEF 710


>gi|62865618 toll-like receptor 10 precursor [Homo sapiens]
          Length = 811

 Score = 35.0 bits (79), Expect = 0.12
 Identities = 33/136 (24%), Positives = 57/136 (41%), Gaps = 16/136 (11%)

Query: 121 AVLASLLVLLALLLAALLYVKCRLNVLLWYQDAYGEV-------------EINDGKLYDA 167
           A+L   +V++ L+L   +   C    L WY    G+              ++     + A
Sbjct: 577 ALLIVTIVVIMLVLGLAVAFCCLHFDLPWYLRMLGQCTQTWHRVRKTTQEQLKRNVRFHA 636

Query: 168 YVSYSDCPEDRKFVNFILKPQLERRRGYKLF-LDDRDLLPRAEPSADLLVNLSRCRRLIV 226
           ++SYS+   D  +V   L P LE+  G  L  L +    P    S +++  + +  + I 
Sbjct: 637 FISYSE--HDSLWVKNELIPNLEKEDGSILICLYESYFDPGKSISENIVSFIEKSYKSIF 694

Query: 227 VLSDAFLSRAWCSHSF 242
           VLS  F+   WC + F
Sbjct: 695 VLSPNFVQNEWCHYEF 710


>gi|58331253 obscurin, cytoskeletal calmodulin and titin-interacting
            RhoGEF isoform a [Homo sapiens]
          Length = 6620

 Score = 35.0 bits (79), Expect = 0.12
 Identities = 23/61 (37%), Positives = 35/61 (57%), Gaps = 7/61 (11%)

Query: 6    DRAPDFLSPSEDQVLRPALGSSVALNCTAWVVSGPHCSLPSVQWLKDGLPLGIGGHYSLH 65
            D AP FL+  ++Q ++   G  V+ +C   VV+G    +PSV+W KDG  L    HY ++
Sbjct: 5123 DAAPVFLTELQNQEVQD--GYPVSFDC---VVTGQ--PMPSVRWFKDGKLLEEDDHYMIN 5175

Query: 66   E 66
            E
Sbjct: 5176 E 5176


>gi|148833506 obscurin, cytoskeletal calmodulin and titin-interacting
            RhoGEF isoform b [Homo sapiens]
          Length = 7968

 Score = 35.0 bits (79), Expect = 0.12
 Identities = 23/61 (37%), Positives = 35/61 (57%), Gaps = 7/61 (11%)

Query: 6    DRAPDFLSPSEDQVLRPALGSSVALNCTAWVVSGPHCSLPSVQWLKDGLPLGIGGHYSLH 65
            D AP FL+  ++Q ++   G  V+ +C   VV+G    +PSV+W KDG  L    HY ++
Sbjct: 5123 DAAPVFLTELQNQEVQD--GYPVSFDC---VVTGQ--PMPSVRWFKDGKLLEEDDHYMIN 5175

Query: 66   E 66
            E
Sbjct: 5176 E 5176


>gi|61742797 basal cell adhesion molecule isoform 2 precursor [Homo
           sapiens]
          Length = 588

 Score = 33.9 bits (76), Expect = 0.27
 Identities = 23/55 (41%), Positives = 29/55 (52%), Gaps = 5/55 (9%)

Query: 10  DFLSPSEDQVLRPALGSSVALNCTAWVVSGPHCSLPSVQWLKDGLPLGIGGHYSL 64
           D L  SE +VL   L SS  +NC+   V G     P+++W KD  PLG G   SL
Sbjct: 362 DPLELSEGKVLSLPLNSSAVVNCS---VHG--LPTPALRWTKDSTPLGDGPMLSL 411


>gi|31543106 basal cell adhesion molecule isoform 1 precursor [Homo
           sapiens]
          Length = 628

 Score = 33.9 bits (76), Expect = 0.27
 Identities = 23/55 (41%), Positives = 29/55 (52%), Gaps = 5/55 (9%)

Query: 10  DFLSPSEDQVLRPALGSSVALNCTAWVVSGPHCSLPSVQWLKDGLPLGIGGHYSL 64
           D L  SE +VL   L SS  +NC+   V G     P+++W KD  PLG G   SL
Sbjct: 362 DPLELSEGKVLSLPLNSSAVVNCS---VHG--LPTPALRWTKDSTPLGDGPMLSL 411


>gi|118572606 hemicentin 1 [Homo sapiens]
          Length = 5635

 Score = 33.9 bits (76), Expect = 0.27
 Identities = 23/78 (29%), Positives = 34/78 (43%), Gaps = 17/78 (21%)

Query: 25   GSSVALNCTAWVVSGPHCSLPSVQWLKDGLPLGIGGHYSLHEYSWVKANLSEVLVSSVLG 84
            GSS ++ C   +  G     PS+ WL+DG PLG+  H ++  +              VL 
Sbjct: 3450 GSSTSMAC---ITDGTPA--PSMAWLRDGQPLGLDAHLTVSTH------------GMVLQ 3492

Query: 85   VNVTSTEVYGAFTCSIQN 102
            +    TE  G +TC   N
Sbjct: 3493 LLKAETEDSGKYTCIASN 3510



 Score = 32.0 bits (71), Expect = 1.0
 Identities = 29/89 (32%), Positives = 37/89 (41%), Gaps = 18/89 (20%)

Query: 14   PSEDQVLRPALGSSVALNCTAWVVSGPHCSLPSVQWLKDGLPLGIGGHYSLHEYSWVKAN 73
            PS+  VL   LG +V L C A  +       P +QWLKDG P+  G    +     V AN
Sbjct: 3253 PSDVSVL---LGENVELVCNANGIP-----TPLIQWLKDGKPIASGETERIR----VSAN 3300

Query: 74   LSEVLVSSVLGVNVTSTEVYGAFTCSIQN 102
                   S L +    T   G +TC   N
Sbjct: 3301 ------GSTLNIYGALTSDTGKYTCVATN 3323



 Score = 30.4 bits (67), Expect = 3.0
 Identities = 24/78 (30%), Positives = 37/78 (47%), Gaps = 19/78 (24%)

Query: 26   SSVALNCTAWVVSGPHCSLPSVQWLKDGLPLGIGGHYSLHEYSWVKANLSEVLVSS-VLG 84
            +SV+L C A   SG    LPS+ W KDG P+ +             +N   +L    +L 
Sbjct: 2402 NSVSLTCEA---SG--IPLPSITWFKDGWPVSL-------------SNSVRILSGGRMLR 2443

Query: 85   VNVTSTEVYGAFTCSIQN 102
            +  T+ E  G +TC ++N
Sbjct: 2444 LMQTTMEDAGQYTCVVRN 2461



 Score = 30.4 bits (67), Expect = 3.0
 Identities = 16/46 (34%), Positives = 24/46 (52%), Gaps = 4/46 (8%)

Query: 45   PSVQWLKDGLPLGIGGHYSL----HEYSWVKANLSEVLVSSVLGVN 86
            P + WLK+GLPL +  H  L         V+A +S+V V + +  N
Sbjct: 3372 PQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASN 3417


>gi|134244585 putative neuronal cell adhesion molecule [Homo
           sapiens]
          Length = 814

 Score = 33.9 bits (76), Expect = 0.27
 Identities = 37/128 (28%), Positives = 49/128 (38%), Gaps = 27/128 (21%)

Query: 7   RAPDFLSPSEDQVLRPALGSSVALNCTAWVVSGPHCSLPSVQWLKDGLPLGIGGHYSLHE 66
           +AP         + RPA G++    C A     PH     V WLK+G  LG GGH  L  
Sbjct: 327 QAPAEFVQHPQSISRPA-GTTAMFTCQAQGEPPPH-----VTWLKNGQVLGPGGHVRL-- 378

Query: 67  YSWVKANLSEVLVSSVLGVNVTSTEVYGAFTCSIQNISFSSFTLQR---------AGPTS 117
               K N S + +S +        E    + C  +N + SS    R          GP  
Sbjct: 379 ----KNNNSTLTISGI------GPEDEAIYQCVAENSAGSSQASARLTVLWAEGLPGPPR 428

Query: 118 HVAAVLAS 125
           +V AV  S
Sbjct: 429 NVRAVSVS 436


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 32.7 bits (73), Expect = 0.61
 Identities = 31/84 (36%), Positives = 38/84 (45%), Gaps = 21/84 (25%)

Query: 24   LGSSVALNCTAWVVSGPHCSLP-SVQWLKDGLPLGIGGHYSL--HEYSWVKANLSEVLVS 80
            LGSS+ + C    VSG   SLP S QW KDG  +     Y L  HE S          VS
Sbjct: 5250 LGSSIHMECK---VSG---SLPISAQWFKDGKEISTSAKYRLVCHERS----------VS 5293

Query: 81   SVLGVNVTSTEVYGAFTCSIQNIS 104
              L VN    E    +TC + N++
Sbjct: 5294 --LEVNNLELEDTANYTCKVSNVA 5315



 Score = 31.2 bits (69), Expect = 1.8
 Identities = 19/77 (24%), Positives = 34/77 (44%), Gaps = 16/77 (20%)

Query: 45    PSVQWLKDGLPLGIGGHYSLHEYSWVKANLSEVLVSSVLGVNVTSTEVYGAFTCSIQNI- 103
             P++ W+KDG PL              + N+ E   S+VL +   + + +G +T +  N  
Sbjct: 24341 PNISWVKDGEPL----------KQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSA 24390

Query: 104   -----SFSSFTLQRAGP 115
                  + S   L++ GP
Sbjct: 24391 GTATENLSVIVLEKPGP 24407



 Score = 30.4 bits (67), Expect = 3.0
 Identities = 18/58 (31%), Positives = 26/58 (44%), Gaps = 10/58 (17%)

Query: 45    PSVQWLKDGLPLGIGGHYSLHEYSWVKANLSEVLVSSVLGVNVTSTEVYGAFTCSIQN 102
             P+  W KDG  +  GG Y           LSE      L ++ T T   G +TC+++N
Sbjct: 32881 PTAIWTKDGKAITQGGKY----------KLSEDKGGFFLEIHKTDTSDSGLYTCTVKN 32928



 Score = 29.6 bits (65), Expect = 5.2
 Identities = 16/56 (28%), Positives = 29/56 (51%), Gaps = 2/56 (3%)

Query: 45    PSVQWLKDGLPLGIGGHYS-LHE-YSWVKANLSEVLVSSVLGVNVTSTEVYGAFTC 98
             P+++W KDG PL +G +   +HE   +   ++ + L        VT+T   G+ +C
Sbjct: 31824 PTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSC 31879


>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 3874

 Score = 32.0 bits (71), Expect = 1.0
 Identities = 24/79 (30%), Positives = 36/79 (45%), Gaps = 18/79 (22%)

Query: 24   LGSSVALNCTAWVVSGPHCSLPSVQWLKDGLPLGIGGHYSLHEYSWVKANLSEVLVSSVL 83
            +G S+ L+C   VV G    +P + W+KDGLPL  G H            L   L +  L
Sbjct: 3041 VGGSIQLDC---VVRGD--PVPDIHWIKDGLPLR-GSH------------LRHQLQNGSL 3082

Query: 84   GVNVTSTEVYGAFTCSIQN 102
             ++ T  +  G + C  +N
Sbjct: 3083 TIHRTERDDAGRYQCLAEN 3101


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.138    0.425 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,276,565
Number of Sequences: 37866
Number of extensions: 842365
Number of successful extensions: 2446
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 40
Number of HSP's that attempted gapping in prelim test: 2255
Number of HSP's gapped (non-prelim): 227
length of query: 410
length of database: 18,247,518
effective HSP length: 105
effective length of query: 305
effective length of database: 14,271,588
effective search space: 4352834340
effective search space used: 4352834340
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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