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Search of human proteins with 190343021
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|190343021 Sec24-related protein D [Homo sapiens]
(1032 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|190343021 Sec24-related protein D [Homo sapiens] 2124 0.0
gi|38373671 SEC24-related protein C [Homo sapiens] 1158 0.0
gi|38373669 SEC24-related protein C [Homo sapiens] 1158 0.0
gi|112382212 SEC24 (S. cerevisiae) homolog B isoform a [Homo sap... 395 e-109
gi|112382214 SEC24 (S. cerevisiae) homolog B isoform b [Homo sap... 393 e-109
gi|116174780 SEC24 related gene family, member A [Homo sapiens] 357 2e-98
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 84 9e-16
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 82 3e-15
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 82 3e-15
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 82 3e-15
gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens] 81 4e-15
gi|160707881 formin 2 [Homo sapiens] 79 2e-14
gi|110832843 TBP-associated factor 4 [Homo sapiens] 75 2e-13
gi|150417989 cyclin K isoform 1 [Homo sapiens] 75 2e-13
gi|163965366 nascent polypeptide-associated complex alpha subuni... 75 4e-13
gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Ho... 74 7e-13
gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Ho... 74 7e-13
gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Ho... 74 7e-13
gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Hom... 74 7e-13
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s... 74 7e-13
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa... 74 7e-13
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s... 74 7e-13
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 73 2e-12
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] 72 4e-12
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 72 4e-12
gi|54860079 nadrin isoform 1 [Homo sapiens] 72 4e-12
gi|54860105 nadrin isoform 2 [Homo sapiens] 72 4e-12
gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 ... 71 5e-12
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 71 6e-12
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 71 6e-12
>gi|190343021 Sec24-related protein D [Homo sapiens]
Length = 1032
Score = 2124 bits (5504), Expect = 0.0
Identities = 1032/1032 (100%), Positives = 1032/1032 (100%)
Query: 1 MSQQGYVATPPYSQPQPGIGLSPPHYGHYGDPSHTASPTGMMKPAGPLGATATRGMLPPG 60
MSQQGYVATPPYSQPQPGIGLSPPHYGHYGDPSHTASPTGMMKPAGPLGATATRGMLPPG
Sbjct: 1 MSQQGYVATPPYSQPQPGIGLSPPHYGHYGDPSHTASPTGMMKPAGPLGATATRGMLPPG 60
Query: 61 PPPPGPHQFGQNGAHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQL 120
PPPPGPHQFGQNGAHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQL
Sbjct: 61 PPPPGPHQFGQNGAHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQL 120
Query: 121 GSQLSAMQINSYGSGMAPPSQGPPGPLSATSLQTPPRPPQPSILQPGSQVLPPPPTTLNG 180
GSQLSAMQINSYGSGMAPPSQGPPGPLSATSLQTPPRPPQPSILQPGSQVLPPPPTTLNG
Sbjct: 121 GSQLSAMQINSYGSGMAPPSQGPPGPLSATSLQTPPRPPQPSILQPGSQVLPPPPTTLNG 180
Query: 181 PGASPLPLPMYRPDGLSGPPPPNAQYQPPPLPGQTLGAGYPPQQANSGPQMAGAQLSYPG 240
PGASPLPLPMYRPDGLSGPPPPNAQYQPPPLPGQTLGAGYPPQQANSGPQMAGAQLSYPG
Sbjct: 181 PGASPLPLPMYRPDGLSGPPPPNAQYQPPPLPGQTLGAGYPPQQANSGPQMAGAQLSYPG 240
Query: 241 GFPGGPAQMAGPPQPQKKLDPDSIPSPIQVIENDRASRGGQVYATNTRGQIPPLVTTDCM 300
GFPGGPAQMAGPPQPQKKLDPDSIPSPIQVIENDRASRGGQVYATNTRGQIPPLVTTDCM
Sbjct: 241 GFPGGPAQMAGPPQPQKKLDPDSIPSPIQVIENDRASRGGQVYATNTRGQIPPLVTTDCM 300
Query: 301 IQDQGNASPRFIRCTTYCFPCTSDMAKQAQIPLAAVIKPFATIPSNESPLYLVNHGESGP 360
IQDQGNASPRFIRCTTYCFPCTSDMAKQAQIPLAAVIKPFATIPSNESPLYLVNHGESGP
Sbjct: 301 IQDQGNASPRFIRCTTYCFPCTSDMAKQAQIPLAAVIKPFATIPSNESPLYLVNHGESGP 360
Query: 361 VRCNRCKAYMCPFMQFIEGGRRYQCGFCNCVNDVPPFYFQHLDHIGRRLDHYEKPELSLG 420
VRCNRCKAYMCPFMQFIEGGRRYQCGFCNCVNDVPPFYFQHLDHIGRRLDHYEKPELSLG
Sbjct: 361 VRCNRCKAYMCPFMQFIEGGRRYQCGFCNCVNDVPPFYFQHLDHIGRRLDHYEKPELSLG 420
Query: 421 SYEYVATLDYCRKSKPPNPPAFIFMIDVSYSNIKNGLVKLICEELKTMLEKIPKEEQEET 480
SYEYVATLDYCRKSKPPNPPAFIFMIDVSYSNIKNGLVKLICEELKTMLEKIPKEEQEET
Sbjct: 421 SYEYVATLDYCRKSKPPNPPAFIFMIDVSYSNIKNGLVKLICEELKTMLEKIPKEEQEET 480
Query: 481 SAIRVGFITYNKVLHFFNVKSNLAQPQMMVVTDVGEVFVPLLDGFLVNYQESQSVIHNLL 540
SAIRVGFITYNKVLHFFNVKSNLAQPQMMVVTDVGEVFVPLLDGFLVNYQESQSVIHNLL
Sbjct: 481 SAIRVGFITYNKVLHFFNVKSNLAQPQMMVVTDVGEVFVPLLDGFLVNYQESQSVIHNLL 540
Query: 541 DQIPDMFADSNENETVFAPVIQAGMEALKAADCPGKLFIFHSSLPTAEAPGKLKNRDDKK 600
DQIPDMFADSNENETVFAPVIQAGMEALKAADCPGKLFIFHSSLPTAEAPGKLKNRDDKK
Sbjct: 541 DQIPDMFADSNENETVFAPVIQAGMEALKAADCPGKLFIFHSSLPTAEAPGKLKNRDDKK 600
Query: 601 LVNTDKEKILFQPQTNVYDSLAKDCVAHGCSVTLFLFPSQYVDVASLGLVPQLTGGTLYK 660
LVNTDKEKILFQPQTNVYDSLAKDCVAHGCSVTLFLFPSQYVDVASLGLVPQLTGGTLYK
Sbjct: 601 LVNTDKEKILFQPQTNVYDSLAKDCVAHGCSVTLFLFPSQYVDVASLGLVPQLTGGTLYK 660
Query: 661 YNNFQMHLDRQQFLNDLRNDIEKKIGFDAIMRVRTSTGFRATDFFGGILMNNTTDVEMAA 720
YNNFQMHLDRQQFLNDLRNDIEKKIGFDAIMRVRTSTGFRATDFFGGILMNNTTDVEMAA
Sbjct: 661 YNNFQMHLDRQQFLNDLRNDIEKKIGFDAIMRVRTSTGFRATDFFGGILMNNTTDVEMAA 720
Query: 721 IDCDKAVTVEFKHDDKLSEDSGALIQCAVLYTTISGQRRLRIHNLGLNCSSQLADLYKSC 780
IDCDKAVTVEFKHDDKLSEDSGALIQCAVLYTTISGQRRLRIHNLGLNCSSQLADLYKSC
Sbjct: 721 IDCDKAVTVEFKHDDKLSEDSGALIQCAVLYTTISGQRRLRIHNLGLNCSSQLADLYKSC 780
Query: 781 ETDALINFFAKSAFKAVLHQPLKVIREILVNQTAHMLACYRKNCASPSAASQLILPDSMK 840
ETDALINFFAKSAFKAVLHQPLKVIREILVNQTAHMLACYRKNCASPSAASQLILPDSMK
Sbjct: 781 ETDALINFFAKSAFKAVLHQPLKVIREILVNQTAHMLACYRKNCASPSAASQLILPDSMK 840
Query: 841 VLPVYMNCLLKNCVLLSRPEISTDERAYQRQLVMTMGVADSQLFFYPQLLPIHTLDVKST 900
VLPVYMNCLLKNCVLLSRPEISTDERAYQRQLVMTMGVADSQLFFYPQLLPIHTLDVKST
Sbjct: 841 VLPVYMNCLLKNCVLLSRPEISTDERAYQRQLVMTMGVADSQLFFYPQLLPIHTLDVKST 900
Query: 901 MLPAAVRCSESRLSEEGIFLLANGLHMFLWLGVSSPPELIQGIFNVPSFAHINTDMTLLP 960
MLPAAVRCSESRLSEEGIFLLANGLHMFLWLGVSSPPELIQGIFNVPSFAHINTDMTLLP
Sbjct: 901 MLPAAVRCSESRLSEEGIFLLANGLHMFLWLGVSSPPELIQGIFNVPSFAHINTDMTLLP 960
Query: 961 EVGNPYSQQLRMIMGIIQQKRPYSMKLTIVKQREQPEMVFRQFLVEDKGLYGGSSYVDFL 1020
EVGNPYSQQLRMIMGIIQQKRPYSMKLTIVKQREQPEMVFRQFLVEDKGLYGGSSYVDFL
Sbjct: 961 EVGNPYSQQLRMIMGIIQQKRPYSMKLTIVKQREQPEMVFRQFLVEDKGLYGGSSYVDFL 1020
Query: 1021 CCVHKEICQLLN 1032
CCVHKEICQLLN
Sbjct: 1021 CCVHKEICQLLN 1032
>gi|38373671 SEC24-related protein C [Homo sapiens]
Length = 1094
Score = 1158 bits (2995), Expect = 0.0
Identities = 599/1061 (56%), Positives = 766/1061 (72%), Gaps = 50/1061 (4%)
Query: 12 YSQPQPGIGLSPPHYGHYGDPSHTASPTGMMKPAGPLGATAT----RGMLPPGPPP---- 63
Y+ P PG +PP PS A P + P G A +G + GP
Sbjct: 44 YNGPVPGYQQTPPQGMSRAPPSSGAPPASTAQ--APCGQAAYGQFGQGDVQNGPSSTVQM 101
Query: 64 ---PGPHQFGQNGAHATGHPPQRFP-GPPPVN----------NVASSHAPYQPSAQSSYP 109
PG FG A PP P GPPP + ++ + AP PS+ +
Sbjct: 102 QRLPGSQPFGSPLAPVGNQPPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFG 161
Query: 110 GPISTSSVTQLGSQLSAMQINSYGSGMAPP---SQGPPGPLSATSLQTPPR--PPQPSIL 164
P S +S + GS ++ SY G APP +QG PG +QTP R P Q S
Sbjct: 162 PPTSLASAS--GSFPNSGLYGSYPQGQAPPLSQAQGHPG------IQTPQRSAPSQASSF 213
Query: 165 QPGSQVLPPPPTTLNG--PGASPLPLPMYRPDGLSGPP---PPNAQYQPP--PLPGQ--T 215
P + P P+ PG S + +P+ +S PP PP Q P PLP
Sbjct: 214 TPPASGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQALPPGTQMTGPLGPLPPMHSP 273
Query: 216 LGAGYPPQQANSGPQMAGAQLSYPGGFPGGPA--QMAGPPQP--QKKLDPDSIPSPIQVI 271
GY PQQ S G Q +Y G +P P GPPQP K+LDPD+IPSPIQVI
Sbjct: 274 QQPGYQPQQNGSFGPARGPQSNYGGPYPAAPTFGSQPGPPQPLPPKRLDPDAIPSPIQVI 333
Query: 272 ENDRASRGGQVYATNTRGQIPPLVTTDCMIQDQGNASPRFIRCTTYCFPCTSDMAKQAQI 331
E+DR +RG + + T RGQ+PPLVTT+ +++DQGNASPR+IRCT+Y PCTSDMAKQAQ+
Sbjct: 334 EDDRNNRGTEPFVTGVRGQVPPLVTTNFLVKDQGNASPRYIRCTSYNIPCTSDMAKQAQV 393
Query: 332 PLAAVIKPFATIPSNESPLYLVNHGESGPVRCNRCKAYMCPFMQFIEGGRRYQCGFCNCV 391
PLAAVIKP A +P E+ Y+V+HGESGP+RCNRCKAYMCPFMQFIEGGRR+QC FC+C+
Sbjct: 394 PLAAVIKPLARLPPEEASPYVVDHGESGPLRCNRCKAYMCPFMQFIEGGRRFQCCFCSCI 453
Query: 392 NDVPPFYFQHLDHIGRRLDHYEKPELSLGSYEYVATLDYCRKSKPPNPPAFIFMIDVSYS 451
NDVPP YFQHLDH G+R+D Y++PELSLGSYE++AT+DYC+ +K P+PPAFIFMIDVSY+
Sbjct: 454 NDVPPQYFQHLDHTGKRVDAYDRPELSLGSYEFLATVDYCKNNKFPSPPAFIFMIDVSYN 513
Query: 452 NIKNGLVKLICEELKTMLEKIPKEEQEETSAIRVGFITYNKVLHFFNVKSNLAQPQMMVV 511
I+ GLV+L+CEELK++L+ +P+E E SAIRVGF+TYNKVLHF+NVKS+LAQPQMMVV
Sbjct: 514 AIRTGLVRLLCEELKSLLDFLPREGGAEESAIRVGFVTYNKVLHFYNVKSSLAQPQMMVV 573
Query: 512 TDVGEVFVPLLDGFLVNYQESQSVIHNLLDQIPDMFADSNENETVFAPVIQAGMEALKAA 571
+DV ++FVPLLDGFLVN ES++VI +LLDQIP+MFAD+ E ETVF PVIQAGMEALKAA
Sbjct: 574 SDVADMFVPLLDGFLVNVNESRAVITSLLDQIPEMFADTRETETVFVPVIQAGMEALKAA 633
Query: 572 DCPGKLFIFHSSLPTAEAPGKLKNRDDKKLVNTDKEKILFQPQTNVYDSLAKDCVAHGCS 631
+C GKLF+FH+SLP AEAPGKLKNRDD+KL+NTDKEK LFQPQT Y +LAK+CVA GC
Sbjct: 634 ECAGKLFLFHTSLPIAEAPGKLKNRDDRKLINTDKEKTLFQPQTGAYQTLAKECVAQGCC 693
Query: 632 VTLFLFPSQYVDVASLGLVPQLTGGTLYKYNNFQMHLDRQQFLNDLRNDIEKKIGFDAIM 691
V LFLFP+QYVDVA+L +VPQLTGG++YKY +FQ+ D+++FL+DLR D++K +GFDA+M
Sbjct: 694 VDLFLFPNQYVDVATLSVVPQLTGGSVYKYASFQVENDQERFLSDLRRDVQKVVGFDAVM 753
Query: 692 RVRTSTGFRATDFFGGILMNNTTDVEMAAIDCDKAVTVEFKHDDKLSEDSGALIQCAVLY 751
RVRTSTG RA DFFG M+NTTDVE+A +D DK VTVEFKHDD+L+E+SGAL+QCA+LY
Sbjct: 754 RVRTSTGIRAVDFFGAFYMSNTTDVELAGLDGDKTVTVEFKHDDRLNEESGALLQCALLY 813
Query: 752 TTISGQRRLRIHNLGLNCSSQLADLYKSCETDALINFFAKSAFKAVLHQPLKVIREILVN 811
T+ +GQRRLRIHNL LNC +QLADLY++CETD LIN+ AK A++ VL+ P+K +R+ L+
Sbjct: 814 TSCAGQRRLRIHNLALNCCTQLADLYRNCETDTLINYMAKFAYRGVLNSPVKAVRDTLIT 873
Query: 812 QTAHMLACYRKNCASPSAASQLILPDSMKVLPVYMNCLLKNCVLLSRPEISTDERAYQRQ 871
Q A +LACYRKNCASPS+A QLILP+ MK+LPVY+NC+LK+ VL E++TD+RAY RQ
Sbjct: 874 QCAQILACYRKNCASPSSAGQLILPECMKLLPVYLNCVLKSDVLQPGAEVTTDDRAYVRQ 933
Query: 872 LVMTMGVADSQLFFYPQLLPIHTLDVKSTMLPAAVRCSESRLSEEGIFLLANGLHMFLWL 931
LV +M V ++ +FFYP+LLP+ V+ST P AVR SE RLS I+LL NGL++FLW+
Sbjct: 934 LVTSMDVTETNVFFYPRLLPLTKSPVESTTEPPAVRASEERLSNGDIYLLENGLNLFLWV 993
Query: 932 GVSSPPELIQGIFNVPSFAHINTDMTLLPEVGNPYSQQLRMIMGIIQQKRPYSMKLTIVK 991
G S ++Q +F+V SF+ I + +++LP + NP S+++R ++ ++ +R MKLT+VK
Sbjct: 994 GASVQQGVVQSLFSVSSFSQITSGLSVLPVLDNPLSKKVRGLIDSLRAQRSRYMKLTVVK 1053
Query: 992 QREQPEMVFRQFLVEDKGLYGGSSYVDFLCCVHKEICQLLN 1032
Q ++ EM+F+ FLVEDK L GG+SYVDFLC +HKEI QLL+
Sbjct: 1054 QEDKMEMLFKHFLVEDKSLSGGASYVDFLCHMHKEIRQLLS 1094
Score = 43.9 bits (102), Expect = 8e-04
Identities = 69/275 (25%), Positives = 84/275 (30%), Gaps = 78/275 (28%)
Query: 92 NVASSHAPYQPSAQSS--YPGPISTSSVTQLGSQLSAMQINSY-------------GSGM 136
NV S P P Q YPG +S Q GS A+ +Y G
Sbjct: 2 NVNQSVPPVPPFGQPQPIYPGYHQSSYGGQSGSTAPAIPYGAYNGPVPGYQQTPPQGMSR 61
Query: 137 APPSQGPP------------------------GPLSATSLQTPPRPP-----------QP 161
APPS G P GP S +Q P QP
Sbjct: 62 APPSSGAPPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQRLPGSQPFGSPLAPVGNQP 121
Query: 162 SILQPGSQVLPPPPTT------LNGPGASPLPLPMYRPDGLSGPPPPNAQYQPPPLPGQT 215
+LQP PPPT+ L+G S P GL PP + P
Sbjct: 122 PVLQP----YGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTSLASASGSFPNSG 177
Query: 216 LGAGYPPQQA----------------NSGPQMAGAQLSYPGGFPGGPAQMAGPPQPQKKL 259
L YP QA S P A + G P P+ M GP P +
Sbjct: 178 LYGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQASSFTPPASGGPRLPS-MTGPLLPGQSF 236
Query: 260 DPDSIPSPIQVIENDRASRGGQVYATNTRGQIPPL 294
S+ P V +A G T G +PP+
Sbjct: 237 GGPSVSQPNHVSSPPQALPPG-TQMTGPLGPLPPM 270
Score = 43.9 bits (102), Expect = 8e-04
Identities = 41/149 (27%), Positives = 53/149 (35%), Gaps = 18/149 (12%)
Query: 7 VATPPYSQPQPGIGLSPPHYGHYGDPSHTASPTGMMKPAGPLGATATRGMLPPGPPPPGP 66
+ TP S P +PP G PS T GP + PP PPG
Sbjct: 199 IQTPQRSAPSQASSFTPPASGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQALPPGT 258
Query: 67 HQFGQNGAHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGSQLSA 126
G G H PQ+ PG P N S P + QS+Y GP +
Sbjct: 259 QMTGPLGPLPPMHSPQQ-PGYQPQQN--GSFGPAR-GPQSNYGGPYPAAP---------- 304
Query: 127 MQINSYGSGMAPPSQGPPGPLSATSLQTP 155
++GS PP PP L ++ +P
Sbjct: 305 ----TFGSQPGPPQPLPPKRLDPDAIPSP 329
>gi|38373669 SEC24-related protein C [Homo sapiens]
Length = 1094
Score = 1158 bits (2995), Expect = 0.0
Identities = 599/1061 (56%), Positives = 766/1061 (72%), Gaps = 50/1061 (4%)
Query: 12 YSQPQPGIGLSPPHYGHYGDPSHTASPTGMMKPAGPLGATAT----RGMLPPGPPP---- 63
Y+ P PG +PP PS A P + P G A +G + GP
Sbjct: 44 YNGPVPGYQQTPPQGMSRAPPSSGAPPASTAQ--APCGQAAYGQFGQGDVQNGPSSTVQM 101
Query: 64 ---PGPHQFGQNGAHATGHPPQRFP-GPPPVN----------NVASSHAPYQPSAQSSYP 109
PG FG A PP P GPPP + ++ + AP PS+ +
Sbjct: 102 QRLPGSQPFGSPLAPVGNQPPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFG 161
Query: 110 GPISTSSVTQLGSQLSAMQINSYGSGMAPP---SQGPPGPLSATSLQTPPR--PPQPSIL 164
P S +S + GS ++ SY G APP +QG PG +QTP R P Q S
Sbjct: 162 PPTSLASAS--GSFPNSGLYGSYPQGQAPPLSQAQGHPG------IQTPQRSAPSQASSF 213
Query: 165 QPGSQVLPPPPTTLNG--PGASPLPLPMYRPDGLSGPP---PPNAQYQPP--PLPGQ--T 215
P + P P+ PG S + +P+ +S PP PP Q P PLP
Sbjct: 214 TPPASGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQALPPGTQMTGPLGPLPPMHSP 273
Query: 216 LGAGYPPQQANSGPQMAGAQLSYPGGFPGGPA--QMAGPPQP--QKKLDPDSIPSPIQVI 271
GY PQQ S G Q +Y G +P P GPPQP K+LDPD+IPSPIQVI
Sbjct: 274 QQPGYQPQQNGSFGPARGPQSNYGGPYPAAPTFGSQPGPPQPLPPKRLDPDAIPSPIQVI 333
Query: 272 ENDRASRGGQVYATNTRGQIPPLVTTDCMIQDQGNASPRFIRCTTYCFPCTSDMAKQAQI 331
E+DR +RG + + T RGQ+PPLVTT+ +++DQGNASPR+IRCT+Y PCTSDMAKQAQ+
Sbjct: 334 EDDRNNRGTEPFVTGVRGQVPPLVTTNFLVKDQGNASPRYIRCTSYNIPCTSDMAKQAQV 393
Query: 332 PLAAVIKPFATIPSNESPLYLVNHGESGPVRCNRCKAYMCPFMQFIEGGRRYQCGFCNCV 391
PLAAVIKP A +P E+ Y+V+HGESGP+RCNRCKAYMCPFMQFIEGGRR+QC FC+C+
Sbjct: 394 PLAAVIKPLARLPPEEASPYVVDHGESGPLRCNRCKAYMCPFMQFIEGGRRFQCCFCSCI 453
Query: 392 NDVPPFYFQHLDHIGRRLDHYEKPELSLGSYEYVATLDYCRKSKPPNPPAFIFMIDVSYS 451
NDVPP YFQHLDH G+R+D Y++PELSLGSYE++AT+DYC+ +K P+PPAFIFMIDVSY+
Sbjct: 454 NDVPPQYFQHLDHTGKRVDAYDRPELSLGSYEFLATVDYCKNNKFPSPPAFIFMIDVSYN 513
Query: 452 NIKNGLVKLICEELKTMLEKIPKEEQEETSAIRVGFITYNKVLHFFNVKSNLAQPQMMVV 511
I+ GLV+L+CEELK++L+ +P+E E SAIRVGF+TYNKVLHF+NVKS+LAQPQMMVV
Sbjct: 514 AIRTGLVRLLCEELKSLLDFLPREGGAEESAIRVGFVTYNKVLHFYNVKSSLAQPQMMVV 573
Query: 512 TDVGEVFVPLLDGFLVNYQESQSVIHNLLDQIPDMFADSNENETVFAPVIQAGMEALKAA 571
+DV ++FVPLLDGFLVN ES++VI +LLDQIP+MFAD+ E ETVF PVIQAGMEALKAA
Sbjct: 574 SDVADMFVPLLDGFLVNVNESRAVITSLLDQIPEMFADTRETETVFVPVIQAGMEALKAA 633
Query: 572 DCPGKLFIFHSSLPTAEAPGKLKNRDDKKLVNTDKEKILFQPQTNVYDSLAKDCVAHGCS 631
+C GKLF+FH+SLP AEAPGKLKNRDD+KL+NTDKEK LFQPQT Y +LAK+CVA GC
Sbjct: 634 ECAGKLFLFHTSLPIAEAPGKLKNRDDRKLINTDKEKTLFQPQTGAYQTLAKECVAQGCC 693
Query: 632 VTLFLFPSQYVDVASLGLVPQLTGGTLYKYNNFQMHLDRQQFLNDLRNDIEKKIGFDAIM 691
V LFLFP+QYVDVA+L +VPQLTGG++YKY +FQ+ D+++FL+DLR D++K +GFDA+M
Sbjct: 694 VDLFLFPNQYVDVATLSVVPQLTGGSVYKYASFQVENDQERFLSDLRRDVQKVVGFDAVM 753
Query: 692 RVRTSTGFRATDFFGGILMNNTTDVEMAAIDCDKAVTVEFKHDDKLSEDSGALIQCAVLY 751
RVRTSTG RA DFFG M+NTTDVE+A +D DK VTVEFKHDD+L+E+SGAL+QCA+LY
Sbjct: 754 RVRTSTGIRAVDFFGAFYMSNTTDVELAGLDGDKTVTVEFKHDDRLNEESGALLQCALLY 813
Query: 752 TTISGQRRLRIHNLGLNCSSQLADLYKSCETDALINFFAKSAFKAVLHQPLKVIREILVN 811
T+ +GQRRLRIHNL LNC +QLADLY++CETD LIN+ AK A++ VL+ P+K +R+ L+
Sbjct: 814 TSCAGQRRLRIHNLALNCCTQLADLYRNCETDTLINYMAKFAYRGVLNSPVKAVRDTLIT 873
Query: 812 QTAHMLACYRKNCASPSAASQLILPDSMKVLPVYMNCLLKNCVLLSRPEISTDERAYQRQ 871
Q A +LACYRKNCASPS+A QLILP+ MK+LPVY+NC+LK+ VL E++TD+RAY RQ
Sbjct: 874 QCAQILACYRKNCASPSSAGQLILPECMKLLPVYLNCVLKSDVLQPGAEVTTDDRAYVRQ 933
Query: 872 LVMTMGVADSQLFFYPQLLPIHTLDVKSTMLPAAVRCSESRLSEEGIFLLANGLHMFLWL 931
LV +M V ++ +FFYP+LLP+ V+ST P AVR SE RLS I+LL NGL++FLW+
Sbjct: 934 LVTSMDVTETNVFFYPRLLPLTKSPVESTTEPPAVRASEERLSNGDIYLLENGLNLFLWV 993
Query: 932 GVSSPPELIQGIFNVPSFAHINTDMTLLPEVGNPYSQQLRMIMGIIQQKRPYSMKLTIVK 991
G S ++Q +F+V SF+ I + +++LP + NP S+++R ++ ++ +R MKLT+VK
Sbjct: 994 GASVQQGVVQSLFSVSSFSQITSGLSVLPVLDNPLSKKVRGLIDSLRAQRSRYMKLTVVK 1053
Query: 992 QREQPEMVFRQFLVEDKGLYGGSSYVDFLCCVHKEICQLLN 1032
Q ++ EM+F+ FLVEDK L GG+SYVDFLC +HKEI QLL+
Sbjct: 1054 QEDKMEMLFKHFLVEDKSLSGGASYVDFLCHMHKEIRQLLS 1094
Score = 43.9 bits (102), Expect = 8e-04
Identities = 69/275 (25%), Positives = 84/275 (30%), Gaps = 78/275 (28%)
Query: 92 NVASSHAPYQPSAQSS--YPGPISTSSVTQLGSQLSAMQINSY-------------GSGM 136
NV S P P Q YPG +S Q GS A+ +Y G
Sbjct: 2 NVNQSVPPVPPFGQPQPIYPGYHQSSYGGQSGSTAPAIPYGAYNGPVPGYQQTPPQGMSR 61
Query: 137 APPSQGPP------------------------GPLSATSLQTPPRPP-----------QP 161
APPS G P GP S +Q P QP
Sbjct: 62 APPSSGAPPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQRLPGSQPFGSPLAPVGNQP 121
Query: 162 SILQPGSQVLPPPPTT------LNGPGASPLPLPMYRPDGLSGPPPPNAQYQPPPLPGQT 215
+LQP PPPT+ L+G S P GL PP + P
Sbjct: 122 PVLQP----YGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTSLASASGSFPNSG 177
Query: 216 LGAGYPPQQA----------------NSGPQMAGAQLSYPGGFPGGPAQMAGPPQPQKKL 259
L YP QA S P A + G P P+ M GP P +
Sbjct: 178 LYGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQASSFTPPASGGPRLPS-MTGPLLPGQSF 236
Query: 260 DPDSIPSPIQVIENDRASRGGQVYATNTRGQIPPL 294
S+ P V +A G T G +PP+
Sbjct: 237 GGPSVSQPNHVSSPPQALPPG-TQMTGPLGPLPPM 270
Score = 43.9 bits (102), Expect = 8e-04
Identities = 41/149 (27%), Positives = 53/149 (35%), Gaps = 18/149 (12%)
Query: 7 VATPPYSQPQPGIGLSPPHYGHYGDPSHTASPTGMMKPAGPLGATATRGMLPPGPPPPGP 66
+ TP S P +PP G PS T GP + PP PPG
Sbjct: 199 IQTPQRSAPSQASSFTPPASGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQALPPGT 258
Query: 67 HQFGQNGAHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGSQLSA 126
G G H PQ+ PG P N S P + QS+Y GP +
Sbjct: 259 QMTGPLGPLPPMHSPQQ-PGYQPQQN--GSFGPAR-GPQSNYGGPYPAAP---------- 304
Query: 127 MQINSYGSGMAPPSQGPPGPLSATSLQTP 155
++GS PP PP L ++ +P
Sbjct: 305 ----TFGSQPGPPQPLPPKRLDPDAIPSP 329
>gi|112382212 SEC24 (S. cerevisiae) homolog B isoform a [Homo sapiens]
Length = 1268
Score = 395 bits (1014), Expect = e-109
Identities = 292/996 (29%), Positives = 472/996 (47%), Gaps = 80/996 (8%)
Query: 80 PPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGSQLSAMQINSYGSGMAPP 139
PP+ P V + +S + + +++P TS VTQ S+L + YG +
Sbjct: 307 PPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTS-VTQ-PSELLQQKGVQYGEYVNNQ 364
Query: 140 SQGPPGPLSATS--------------------LQTPPRPPQPSILQPGSQVLPPPPTTLN 179
+ P PLS+TS P P L+ GS P L+
Sbjct: 365 ASSAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGSY-----PDMLS 419
Query: 180 GPGASPLPLPMYRPDGLSGPPPPNAQYQPPPLPGQT---LGAGYPPQQAN----SGPQMA 232
+SP P P PD S P P +A P P + G GYP Q + P ++
Sbjct: 420 SSASSPAPDPAPEPDPASAPAPASAPAPVVPQPSKMAKPFGYGYPTLQPGYQNATAPLIS 479
Query: 233 GAQLSYP--GGFPGGPAQMAGPPQPQKKLDPDSIPSPIQVIENDRASRGGQVYATNTRGQ 290
G Q S P GF P Q G Q + S+ S Q E+ R V T R
Sbjct: 480 GVQPSNPVYSGFQQYPQQYPGVNQLSSSIGGLSLQSSPQP-ESLRP-----VNLTQERNI 533
Query: 291 IP------PLVTTDCMIQDQGNASPRFIRCTTYCFPCTSDMAKQAQIPLAAVIKPFATIP 344
+P P+ + ++ N SP RCT P T + +A++PL ++ PF +
Sbjct: 534 LPMTPVWAPVPNLNADLKKL-NCSPDSFRCTLTNIPQTQALLNKAKLPLGLLLHPFRDL- 591
Query: 345 SNESPLYLVNHGESGPVRCNRCKAYMCPFMQFIEGGRRYQCGFCNCVNDVPPFYFQHLDH 404
+ P+ N VRC C+ Y+ PF+ FI+ RR++C C VNDVP F +
Sbjct: 592 -TQLPVITSNT----IVRCRSCRTYINPFVSFIDQ-RRWKCNLCYRVNDVPE-EFMYNPL 644
Query: 405 IGRRLDHYEKPELSLGSYEYVATLDYCRKSKPPNPPAFIFMIDVSYSNIKNGLVKLICEE 464
+ +++PE+ + E++A+ DY + PP P ++F++DVS++ ++ G + ++C+
Sbjct: 645 TRSYGEPHKRPEVQNSTVEFIASSDYMLR--PPQPAVYLFVLDVSHNAVEAGYLTILCQS 702
Query: 465 LKTMLEKIPKEEQEETSAIRVGFITYNKVLHFFNVKSNLAQPQMMVVTDVGEVFVPLLDG 524
L L+K+P + S R+GF+T++ +HF+N++ L+QPQM++V+D+ +VF+P D
Sbjct: 703 LLENLDKLPGD-----SRTRIGFMTFDSTIHFYNLQEGLSQPQMLIVSDIDDVFLPTPDS 757
Query: 525 FLVNYQESQSVIHNLLDQIPDMFADSNENETVFAPVIQAGMEALKAADCPGKLFIFHSSL 584
LVN ES+ +I +LL+ +P+MF ++ E + P +QA + + G++ +F + L
Sbjct: 758 LLVNLYESKELIKDLLNALPNMFTNTRETHSALGPALQAAFKLMSPTG--GRVSVFQTQL 815
Query: 585 PTAEAPGKLKNRDDKKLVNTDKEKILFQPQTNVYDSLAKDCVAHGCSVTLFLFPSQYVDV 644
P+ A G L++R+D ++ K P T+ Y LA DC +V LFL SQY D+
Sbjct: 816 PSLGA-GLLQSREDPNQRSSTKVVQHLGPATDFYKKLALDCSGQQTAVDLFLLSSQYSDL 874
Query: 645 ASLGLVPQLTGGTLYKYNNFQMHLDRQQ---FLNDLRNDIEKKIGFDAIMRVRTSTGFRA 701
ASL + + + G +Y Y +F + Q DL+ + +KIGF+A+MR+R + G
Sbjct: 875 ASLACMSKYSAGCIYYYPSFHYTHNPSQAEKLQKDLKRYLTRKIGFEAVMRIRCTKGLSM 934
Query: 702 TDFFGGILMNNTTDVEMAAIDCDKAVTVEFKHDDKLSEDSGALIQCAVLYTTISGQRRLR 761
F G + +T + +A I+ D V+ ++ L++ S Q A+LYT+ G+RR+R
Sbjct: 935 HTFHGNFFVRSTDLLSLANINPDAGFAVQLSIEESLTDTSLVCFQTALLYTSSKGERRIR 994
Query: 762 IHNLGLNCSSQLADLYKSCETDALINFFAKSAFKAVLHQPLKVIREILVNQTAHMLACYR 821
+H L L S LAD+Y + A I A A + L R+ LVN L+ Y
Sbjct: 995 VHTLCLPVVSSLADVYAGVDVQAAICLLANMAVDRSVSSSLSDARDALVNAVVDSLSAY- 1053
Query: 822 KNCASPSAASQLILPDSMKVLPVYMNCLLKNCVLLSRPEISTDERAYQRQLVMTMGVADS 881
+ S S L+ P S+K+ P+Y+ LLK + D+R Y + + +
Sbjct: 1054 GSTVSNLQHSALMAPSSLKLFPLYVLALLKQKAFRTGTSTRLDDRVYAMCQIKSQPLVHL 1113
Query: 882 QLFFYPQLLPIHTLDVKSTM--------LPAAVRCSESRLSEEGIFLLANGLHMFLWLGV 933
+P L I L + + P + S +L+ EG FL+ G ++W+G
Sbjct: 1114 MKMIHPNLYRIDRLTDEGAVHVNDRIVPQPPLQKLSAEKLTREGAFLMDCGSVFYIWVGK 1173
Query: 934 SSPPELIQGIFNVPSFAHINTDMTLLPEVGNPYSQQLRMIMGIIQQKRPYSMKLTIVKQR 993
I+ + +FA I MT LPE+ S++ R + ++ RP S L IVK
Sbjct: 1174 GCDNNFIEDVLGYTNFASIPQKMTHLPELDTLSSERARSFITWLRDSRPLSPILHIVKDE 1233
Query: 994 EQPEMVFRQFLVEDKGLYGGSSYVDFLCCVHKEICQ 1029
+ F Q L+ED+ SY +FL V ++IC+
Sbjct: 1234 SPAKAEFFQHLIEDR-TEAAFSYYEFLLHVQQQICK 1268
Score = 31.6 bits (70), Expect = 4.0
Identities = 52/245 (21%), Positives = 77/245 (31%), Gaps = 30/245 (12%)
Query: 32 PSHTASPTGMMKPAGPLGATATRGMLPPGPPPPGPHQFGQNGAHATGHPPQRFPGPPPVN 91
P+ ++ P + G A G P P GP QNG G N
Sbjct: 4 PAGSSHPAASARIPPKFGGAAVSGAAAPAGPGAGPAPHQQNGPAQNQMQVPSGYGLHHQN 63
Query: 92 NVA-SSHAPYQPSAQSSYP-----GPISTSSVTQLGSQLSAMQINSYGSGMAPPSQGPPG 145
+A S H P +S P G ++ T ++ +N S+GPP
Sbjct: 64 YIAPSGHYSQGPGKMTSLPLDTQCGDYYSALYTVPTQNVTPNTVNQQPGAQQLYSRGPPA 123
Query: 146 P--------------LSATSLQTPPRPPQPSILQPGSQVLPPPPTTLNGPGASPLPLPMY 191
P SA+ L T P S + + ++ P Y
Sbjct: 124 PHIVGSTLGSFQGAASSASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQGFPSTCGHY 183
Query: 192 RPDGLSGPPPPNAQYQPPPLP-GQTLGAGYPPQQA-------NSGPQMAGAQLSYPGGFP 243
+S P+ Y P LP G T G + Q A ++ +S+P P
Sbjct: 184 AMSTVSNAAYPSVSY--PSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHPSPLP 241
Query: 244 GGPAQ 248
P+Q
Sbjct: 242 PLPSQ 246
>gi|112382214 SEC24 (S. cerevisiae) homolog B isoform b [Homo sapiens]
Length = 1233
Score = 393 bits (1010), Expect = e-109
Identities = 273/908 (30%), Positives = 442/908 (48%), Gaps = 58/908 (6%)
Query: 148 SATSLQTPPRPPQPSILQPGSQVLPPPPTTLNGPGASPLPLPMYRPDGLSGPPPPNAQYQ 207
S+T+ P P L+ GS P L+ +SP P P PD S P P +A
Sbjct: 358 SSTTSSASPMPNSYDALEGGSY-----PDMLSSSASSPAPDPAPEPDPASAPAPASAPAP 412
Query: 208 PPPLPGQT---LGAGYPPQQAN----SGPQMAGAQLSYP--GGFPGGPAQMAGPPQPQKK 258
P P + G GYP Q + P ++G Q S P GF P Q G Q
Sbjct: 413 VVPQPSKMAKPFGYGYPTLQPGYQNATAPLISGVQPSNPVYSGFQQYPQQYPGVNQLSSS 472
Query: 259 LDPDSIPSPIQVIENDRASRGGQVYATNTRGQIP------PLVTTDCMIQDQGNASPRFI 312
+ S+ S Q E+ R V T R +P P+ + ++ N SP
Sbjct: 473 IGGLSLQSSPQP-ESLRP-----VNLTQERNILPMTPVWAPVPNLNADLKKL-NCSPDSF 525
Query: 313 RCTTYCFPCTSDMAKQAQIPLAAVIKPFATIPSNESPLYLVNHGESGPVRCNRCKAYMCP 372
RCT P T + +A++PL ++ PF + + P+ N VRC C+ Y+ P
Sbjct: 526 RCTLTNIPQTQALLNKAKLPLGLLLHPFRDL--TQLPVITSNT----IVRCRSCRTYINP 579
Query: 373 FMQFIEGGRRYQCGFCNCVNDVPPFYFQHLDHIGRRLDHYEKPELSLGSYEYVATLDYCR 432
F+ FI+ RR++C C VNDVP F + + +++PE+ + E++A+ DY
Sbjct: 580 FVSFIDQ-RRWKCNLCYRVNDVPE-EFMYNPLTRSYGEPHKRPEVQNSTVEFIASSDYML 637
Query: 433 KSKPPNPPAFIFMIDVSYSNIKNGLVKLICEELKTMLEKIPKEEQEETSAIRVGFITYNK 492
+ PP P ++F++DVS++ ++ G + ++C+ L L+K+P + S R+GF+T++
Sbjct: 638 R--PPQPAVYLFVLDVSHNAVEAGYLTILCQSLLENLDKLPGD-----SRTRIGFMTFDS 690
Query: 493 VLHFFNVKSNLAQPQMMVVTDVGEVFVPLLDGFLVNYQESQSVIHNLLDQIPDMFADSNE 552
+HF+N++ L+QPQM++V+D+ +VF+P D LVN ES+ +I +LL+ +P+MF ++ E
Sbjct: 691 TIHFYNLQEGLSQPQMLIVSDIDDVFLPTPDSLLVNLYESKELIKDLLNALPNMFTNTRE 750
Query: 553 NETVFAPVIQAGMEALKAADCPGKLFIFHSSLPTAEAPGKLKNRDDKKLVNTDKEKILFQ 612
+ P +QA + + G++ +F + LP+ A G L++R+D ++ K
Sbjct: 751 THSALGPALQAAFKLMSPTG--GRVSVFQTQLPSLGA-GLLQSREDPNQRSSTKVVQHLG 807
Query: 613 PQTNVYDSLAKDCVAHGCSVTLFLFPSQYVDVASLGLVPQLTGGTLYKYNNFQMHLDRQQ 672
P T+ Y LA DC +V LFL SQY D+ASL + + + G +Y Y +F + Q
Sbjct: 808 PATDFYKKLALDCSGQQTAVDLFLLSSQYSDLASLACMSKYSAGCIYYYPSFHYTHNPSQ 867
Query: 673 ---FLNDLRNDIEKKIGFDAIMRVRTSTGFRATDFFGGILMNNTTDVEMAAIDCDKAVTV 729
DL+ + +KIGF+A+MR+R + G F G + +T + +A I+ D V
Sbjct: 868 AEKLQKDLKRYLTRKIGFEAVMRIRCTKGLSMHTFHGNFFVRSTDLLSLANINPDAGFAV 927
Query: 730 EFKHDDKLSEDSGALIQCAVLYTTISGQRRLRIHNLGLNCSSQLADLYKSCETDALINFF 789
+ ++ L++ S Q A+LYT+ G+RR+R+H L L S LAD+Y + A I
Sbjct: 928 QLSIEESLTDTSLVCFQTALLYTSSKGERRIRVHTLCLPVVSSLADVYAGVDVQAAICLL 987
Query: 790 AKSAFKAVLHQPLKVIREILVNQTAHMLACYRKNCASPSAASQLILPDSMKVLPVYMNCL 849
A A + L R+ LVN L+ Y + S S L+ P S+K+ P+Y+ L
Sbjct: 988 ANMAVDRSVSSSLSDARDALVNAVVDSLSAY-GSTVSNLQHSALMAPSSLKLFPLYVLAL 1046
Query: 850 LKNCVLLSRPEISTDERAYQRQLVMTMGVADSQLFFYPQLLPIHTLDVKSTM-------- 901
LK + D+R Y + + + +P L I L + +
Sbjct: 1047 LKQKAFRTGTSTRLDDRVYAMCQIKSQPLVHLMKMIHPNLYRIDRLTDEGAVHVNDRIVP 1106
Query: 902 LPAAVRCSESRLSEEGIFLLANGLHMFLWLGVSSPPELIQGIFNVPSFAHINTDMTLLPE 961
P + S +L+ EG FL+ G ++W+G I+ + +FA I MT LPE
Sbjct: 1107 QPPLQKLSAEKLTREGAFLMDCGSVFYIWVGKGCDNNFIEDVLGYTNFASIPQKMTHLPE 1166
Query: 962 VGNPYSQQLRMIMGIIQQKRPYSMKLTIVKQREQPEMVFRQFLVEDKGLYGGSSYVDFLC 1021
+ S++ R + ++ RP S L IVK + F Q L+ED+ SY +FL
Sbjct: 1167 LDTLSSERARSFITWLRDSRPLSPILHIVKDESPAKAEFFQHLIEDR-TEAAFSYYEFLL 1225
Query: 1022 CVHKEICQ 1029
V ++IC+
Sbjct: 1226 HVQQQICK 1233
Score = 31.6 bits (70), Expect = 4.0
Identities = 52/245 (21%), Positives = 77/245 (31%), Gaps = 30/245 (12%)
Query: 32 PSHTASPTGMMKPAGPLGATATRGMLPPGPPPPGPHQFGQNGAHATGHPPQRFPGPPPVN 91
P+ ++ P + G A G P P GP QNG G N
Sbjct: 4 PAGSSHPAASARIPPKFGGAAVSGAAAPAGPGAGPAPHQQNGPAQNQMQVPSGYGLHHQN 63
Query: 92 NVA-SSHAPYQPSAQSSYP-----GPISTSSVTQLGSQLSAMQINSYGSGMAPPSQGPPG 145
+A S H P +S P G ++ T ++ +N S+GPP
Sbjct: 64 YIAPSGHYSQGPGKMTSLPLDTQCGDYYSALYTVPTQNVTPNTVNQQPGAQQLYSRGPPA 123
Query: 146 P--------------LSATSLQTPPRPPQPSILQPGSQVLPPPPTTLNGPGASPLPLPMY 191
P SA+ L T P S + + ++ P Y
Sbjct: 124 PHIVGSTLGSFQGAASSASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQGFPSTCGHY 183
Query: 192 RPDGLSGPPPPNAQYQPPPLP-GQTLGAGYPPQQA-------NSGPQMAGAQLSYPGGFP 243
+S P+ Y P LP G T G + Q A ++ +S+P P
Sbjct: 184 AMSTVSNAAYPSVSY--PSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHPSPLP 241
Query: 244 GGPAQ 248
P+Q
Sbjct: 242 PLPSQ 246
>gi|116174780 SEC24 related gene family, member A [Homo sapiens]
Length = 1093
Score = 357 bits (917), Expect = 2e-98
Identities = 258/983 (26%), Positives = 453/983 (46%), Gaps = 95/983 (9%)
Query: 57 LPPGPPPPGPHQFGQNGAHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSS 116
+PP PP P F H G PP GPPPV + + Y+ Q + ++
Sbjct: 192 VPPLVNPPLPTTFQPGAPH--GPPPAG--GPPPVRALTPLTSSYRDVPQPLFNSAVNQEG 247
Query: 117 VTQLGSQLSAMQINSYGSGMAPPSQGPPGPLSATSLQTPPRPPQPSILQPGSQVLPPPPT 176
+T + S + +SY + G L AT T P + LPP
Sbjct: 248 ITSNTNNGSMVVHSSY-------DEIEGGGLLATPQLTNKNPKMSRSVGYSYPSLPPGYQ 300
Query: 177 TLNGPGASPLPLPMYRPDGLSGPPPPNAQYQPPPLPGQTLGAGYPPQQANSGPQMAGAQL 236
PGA+ +P P L+ P P A Q P LGA + M+G L
Sbjct: 301 NTTPPGATGVP-----PSSLNYPSGPQAFTQTP------LGANHLTTS------MSGLSL 343
Query: 237 SYPGGFPGGPAQMAGPPQPQKKLDPDSIPSPIQVIENDRASRGGQVYATNTRGQIPPLVT 296
G ++ Q + L + P+ + D
Sbjct: 344 QPEG------LRVVNLLQERNMLPSTPLKPPVPNLHED---------------------- 375
Query: 297 TDCMIQDQGNASPRFIRCTTYCFPCTSDMAKQAQIPLAAVIKPFATIPSNESPLYLVNHG 356
IQ N +P RCT P T + +A++PL ++ PF + + L
Sbjct: 376 ----IQKL-NCNPELFRCTLTSIPQTQALLNKAKLPLGLLLHPFKDL------VQLPVVT 424
Query: 357 ESGPVRCNRCKAYMCPFMQFIEGGRRYQCGFCNCVNDVPP-FYFQHLDHIGRRLDHYEKP 415
S VRC C+ Y+ PF+ F++ RR++C C VNDVP F + L + + + +P
Sbjct: 425 SSTIVRCRSCRTYINPFVSFLDQ-RRWKCNLCYRVNDVPEEFLYNPLTRVYG--EPHRRP 481
Query: 416 ELSLGSYEYVATLDYCRKSKPPNPPAFIFMIDVSYSNIKNGLVKLICEELKTMLEKIPKE 475
E+ + E++A +Y + PP PP ++F+ DVS++ ++ G + +C+ L L+ +P
Sbjct: 482 EVQNATIEFMAPSEYMLR--PPQPPVYLFVFDVSHNAVETGYLNSVCQSLLDNLDLLPGN 539
Query: 476 EQEETSAIRVGFITYNKVLHFFNVKSNLAQPQMMVVTDVGEVFVPLLDGFLVNYQESQSV 535
+ ++GFIT++ +HF+ ++ +L+QPQM++V+D+ +VF+P+ + LVN ES+ +
Sbjct: 540 TRT-----KIGFITFDSTIHFYGLQESLSQPQMLIVSDIEDVFIPMPENLLVNLNESKEL 594
Query: 536 IHNLLDQIPDMFADSNENETVFAPVIQAGMEALKAADCPGKLFIFHSSLPTAEAPGKLKN 595
+ +LL +P MF + E ++ P +QA + + G++ +F + LPT G LK
Sbjct: 595 VQDLLKTLPQMFTKTLETQSALGPALQAAFKLMSPTG--GRMSVFQTQLPTLGV-GALKP 651
Query: 596 RDDKKLVNTDKEKILFQPQTNVYDSLAKDCVAHGCSVTLFLFPSQYVDVASLGLVPQLTG 655
R++ ++ K+ I P T+ Y LA DC +V LFL QY D+ASLG + + +
Sbjct: 652 REEPNHRSSAKD-IHMTPSTDFYKKLALDCSGQQVAVDLFLLSGQYSDLASLGCISRYSA 710
Query: 656 GTLYKYNNFQMH---LDRQQFLNDLRNDIEKKIGFDAIMRVRTSTGFRATDFFGGILMNN 712
G++Y Y ++ + Q+ +L+ + +KIGF+A+MR+R + G F G + +
Sbjct: 711 GSVYYYPSYHHQHNPVQVQKLQKELQRYLTRKIGFEAVMRIRCTKGLSIHTFHGNFFVRS 770
Query: 713 TTDVEMAAIDCDKAVTVEFKHDDKLSEDSGALIQCAVLYTTISGQRRLRIHNLGLNCSSQ 772
T + + ++ D V+ ++ L++ Q A+LYT+ G+RR+R+H L L S
Sbjct: 771 TDLLSLPNVNPDAGYAVQMSVEESLTDTQLVSFQSALLYTSSKGERRIRVHTLCLPVVST 830
Query: 773 LADLYKSCETDALINFFAKSAFKAVLHQPLKVIREILVNQTAHMLACYRKNCASPSAASQ 832
L D++ + A+ A A + L R+ LVN L+ YR + S +
Sbjct: 831 LNDVFLGADVQAISGLLANMAVDRSMTASLSDARDALVNAVIDSLSAYRSSVLS-NQQPG 889
Query: 833 LILPDSMKVLPVYMNCLLKNCVLLSRPEISTDERAYQRQLVMTMGVADSQLFFYPQLLPI 892
L++P S+++ P+++ LLK + DER + V + L +P L +
Sbjct: 890 LMVPFSLRLFPLFVLALLKQKSFQTGTNARLDERIFAMCQVKNQPLVYLMLTTHPSLYRV 949
Query: 893 HTLDVKSTM--------LPAAVRCSESRLSEEGIFLLANGLHMFLWLGVSSPPELIQGIF 944
L + + P ++ S +LS +G FL+ G + LW+G + + +
Sbjct: 950 DNLSDEGALNISDRTIPQPPILQLSVEKLSRDGAFLMDAGSVLMLWVGKNCTQNFLSQVL 1009
Query: 945 NVPSFAHINTDMTLLPEVGNPYSQQLRMIMGIIQQKRPYSMKLTIVKQREQPEMVFRQFL 1004
V ++A I MT LPE+ P S ++ + ++++RP+ L +++ + F Q +
Sbjct: 1010 GVQNYASIPQPMTDLPELDTPESARIIAFISWLREQRPFFPILYVIRDESPMKANFLQNM 1069
Query: 1005 VEDKGLYGGSSYVDFLCCVHKEI 1027
+ED+ SY +FL + +++
Sbjct: 1070 IEDR-TESALSYYEFLLHIQQQV 1091
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 83.6 bits (205), Expect = 9e-16
Identities = 90/270 (33%), Positives = 102/270 (37%), Gaps = 29/270 (10%)
Query: 11 PYSQPQPGIGLSPPHYGHYGDPSHTA-SPTGMMKPAGPLGATATRGMLPPGPPPPGPHQF 69
P P PG PP G D S + SP G KP GP G P GPPPP
Sbjct: 89 PQGPPPPGKPQGPPPQG---DKSRSPRSPPG--KPQGP---PPQGGNQPQGPPPPPGKPQ 140
Query: 70 G---QNGAHATGHPPQRFP-GPPPV--NNVASSHA-PYQPSAQSSYPGPISTSSVTQLGS 122
G Q G G PP P GPPP N SS + P +P G G
Sbjct: 141 GPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGK 200
Query: 123 -QLSAMQINSYGSGMAPPS--QGPP--GPLSATSLQTPPRPPQPSILQPGSQVLPPPPTT 177
Q Q + G PP QGPP G + S ++PP PQ Q G+Q PPP
Sbjct: 201 PQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPP-- 258
Query: 178 LNGPGASPLPLPMYRPDGLSGPPPPNAQYQPPPLPGQTLGAGYPPQQANSGPQMAGAQLS 237
P P P + GPPPP PPP G + P GP G +
Sbjct: 259 ---PPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGG--N 313
Query: 238 YPGGFPGGPAQMAGPPQPQKKLDPDSIPSP 267
P G P P + GPP PQ P P P
Sbjct: 314 QPQGPPPPPGKPQGPP-PQGGNKPQGPPPP 342
Score = 82.4 bits (202), Expect = 2e-15
Identities = 82/274 (29%), Positives = 98/274 (35%), Gaps = 39/274 (14%)
Query: 10 PPYSQPQPGIGLSPPHYGHYGDPSHTASPTGMMKPAG-PLGATATRGMLPPGPPPPG--- 65
PP + SPP P P G P G P G G P GPPPPG
Sbjct: 163 PPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ 222
Query: 66 -PHQFGQNGAHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGSQL 124
P G N + + PP + GPPP P P + P P
Sbjct: 223 GPPPQGDNKSQSARSPPGKPQGPPPQGG-NQPQGPPPPPGKPQGPPP------------- 268
Query: 125 SAMQINSYGSGMAPPS--QGPP--GPLSATSLQTPPRPPQPSILQPGSQVLPPPPTTLNG 180
Q + G PP QGPP G + S ++PP PQ Q G+Q PPP G
Sbjct: 269 ---QGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPP--G 323
Query: 181 PGASPLPLPMYRPDGLSGPPPPNAQYQPPPLPGQTLGAGYPPQQANSGPQMAGAQLSYP- 239
P P +P G PPP Q PP ++ A PP + PQ G P
Sbjct: 324 KPQGPPPQGGNKPQG--PPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPP 381
Query: 240 ---GGFPGGP-----AQMAGPPQPQKKLDPDSIP 265
GG P P Q GPP+P + P P
Sbjct: 382 PPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 415
Score = 76.6 bits (187), Expect = 1e-13
Identities = 80/281 (28%), Positives = 93/281 (33%), Gaps = 45/281 (16%)
Query: 22 SPPHYGHYGDPSHTASPTGMMKPAG-PLGATATRGMLPPGPPPPG----PHQFGQNGAHA 76
SPP P P G P G P G G P GPPPPG P G N + +
Sbjct: 113 SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRS 172
Query: 77 TGHPPQRFPGPPPVNNVASSHAPYQP-----------SAQSSYPGPISTSSVTQLGSQLS 125
+ PP + GPPP P P + P P G S
Sbjct: 173 SRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKS 232
Query: 126 AMQINSYGSGMAPPSQG---PPGPLSATSLQTPPRPPQPSILQPGSQVLPPPP------- 175
+ G PP QG P GP PP PQ Q G++ PPP
Sbjct: 233 QSARSPPGKPQGPPPQGGNQPQGP------PPPPGKPQGPPPQGGNKPQGPPPPGKPQGP 286
Query: 176 ---------TTLNGPGASPLPLPMYRPDGLSGPPPPNAQYQPPPLPGQTLGAGYPPQQAN 226
++ + PG P P PPPP PPP G G PP
Sbjct: 287 PPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP-QGGNKPQGPPPPGKP 345
Query: 227 SGPQMAGAQLSYPGGFPGGPAQMAGPPQPQKKLDPDSIPSP 267
GP G S P G Q GPPQ Q+ +P P P
Sbjct: 346 QGPPPQGGSKSRSARSPPGKPQ--GPPQ-QEGNNPQGPPPP 383
Score = 76.3 bits (186), Expect = 1e-13
Identities = 79/267 (29%), Positives = 96/267 (35%), Gaps = 35/267 (13%)
Query: 10 PPYSQPQPGIGLSPPHYGHYGDPSHTASPTGMMKPAGPLGATATRGMLPP-GPPPPGPHQ 68
PP +P SPP P P G P G +G P GPPPPG Q
Sbjct: 40 PPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ 99
Query: 69 FGQ---NGAHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGSQLS 125
+ + + PP + GPPP P P + P P
Sbjct: 100 GPPPQGDKSRSPRSPPGKPQGPPPQGG-NQPQGPPPPPGKPQGPPP-------------- 144
Query: 126 AMQINSYGSGMAPPS--QGPP--GPLSATSLQTPPRPPQPSILQPGSQVLPPPPTTLNGP 181
Q + G PP QGPP G + S ++PP PQ Q G+Q PPP P
Sbjct: 145 --QGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPP-----P 197
Query: 182 GASPLPLPMYRPDGLSGPPPPNAQYQPPPL-PGQTLGAGYPPQQANSGPQMAGAQLSYPG 240
P P + GPPPP PPP ++ A PP + P G Q P
Sbjct: 198 PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQ---PQ 254
Query: 241 GFPGGPAQMAGPPQPQKKLDPDSIPSP 267
G P P + GPP PQ P P P
Sbjct: 255 GPPPPPGKPQGPP-PQGGNKPQGPPPP 280
Score = 75.9 bits (185), Expect = 2e-13
Identities = 84/259 (32%), Positives = 93/259 (35%), Gaps = 51/259 (19%)
Query: 22 SPPHYGHYGDPSHTASPTGMMKPAGPLGATATRGMLPPGPPPPGPHQFG---QNGAHATG 78
+PP G+ P SP G KP GP G P GPPPP G Q G G
Sbjct: 39 APPQGGN--KPQGPPSPPG--KPQGP---PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQG 91
Query: 79 HPPQRFP-GPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGSQLSAMQINSYGSGMA 137
PP P GPPP + S +P P + P P Q G+Q G
Sbjct: 92 PPPPGKPQGPPPQGD--KSRSPRSPPGKPQGPPP-------QGGNQ---------PQGPP 133
Query: 138 PPS---QGPPGPLSATSLQTPPRPPQPSILQPGSQVLPPPPTTLN------GPGASPLPL 188
PP QGPP P Q PP P +P PPP N P P
Sbjct: 134 PPPGKPQGPP-PQGGNKPQGPPPPGKPQ---------GPPPQGDNKSRSSRSPPGKPQGP 183
Query: 189 PMYRPDGLSGPPPPNAQYQPPPLPGQTLGAGYPPQQANSGPQMAGAQLSYPGGFPGGPAQ 248
P + GPPPP + Q PP G G PP GP G S P G Q
Sbjct: 184 PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQ 243
Query: 249 MAGPPQPQKKLDPDSIPSP 267
GPP PQ P P P
Sbjct: 244 --GPP-PQGGNQPQGPPPP 259
Score = 66.6 bits (161), Expect = 1e-10
Identities = 71/242 (29%), Positives = 85/242 (35%), Gaps = 50/242 (20%)
Query: 31 DPSHTASPTGMMKPAGPLGATATRGMLPPGPPPP-----GPHQFGQNGAHATGHPPQRFP 85
D S SP+ + P GA G P GPP P GP G N PP +
Sbjct: 22 DVSQEESPS--LIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 79
Query: 86 GPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGSQLSAMQINSYGSGMAPPSQGPPG 145
GPPP + P P P P G PP QG
Sbjct: 80 GPPP----QGGNKPQGP------PPP---------------------GKPQGPPPQGD-- 106
Query: 146 PLSATSLQTPPRPPQPSILQPGSQVLPPPPTTLNGPGASPLPLPMYRPDGLSGPPPPNAQ 205
+ S ++PP PQ Q G+Q PPP G P P +P G PPP Q
Sbjct: 107 --KSRSPRSPPGKPQGPPPQGGNQPQGPPPPP--GKPQGPPPQGGNKPQG--PPPPGKPQ 160
Query: 206 YQPPPLPGQTLGAGYPPQQANSGPQMAGAQLSYPGGFPGGPAQMAGPPQPQKKLDPDSIP 265
PP ++ + PP + P G Q P G P P + GPP PQ P P
Sbjct: 161 GPPPQGDNKSRSSRSPPGKPQGPPPQGGNQ---PQGPPPPPGKPQGPP-PQGGNKPQGPP 216
Query: 266 SP 267
P
Sbjct: 217 PP 218
Score = 50.1 bits (118), Expect = 1e-05
Identities = 52/158 (32%), Positives = 56/158 (35%), Gaps = 23/158 (14%)
Query: 11 PYSQPQPGIGLSPPHYGHYGDPSHTA-SPTGMMKPAGPLGATATRGMLPPGPPPPGPHQF 69
P P PG PP G G S ++ SP G KP GP G P GPPPP
Sbjct: 274 PQGPPPPGKPQGPPPQG--GSKSRSSRSPPG--KPQGP---PPQGGNQPQGPPPPPGKPQ 326
Query: 70 G---QNGAHATGHPPQRFP-GPPPVNNVASSHA---PYQPSAQSSYPGPISTSSVTQLGS 122
G Q G G PP P GPPP S A P +P G G
Sbjct: 327 GPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGG 386
Query: 123 QLSAMQINSYGSGMAPPSQGPPGPLSATSLQTPPRPPQ 160
Q APP+ P GP P RPPQ
Sbjct: 387 NPQQPQ--------APPAGQPQGPPRPPQGGRPSRPPQ 416
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 82.0 bits (201), Expect = 3e-15
Identities = 75/235 (31%), Positives = 90/235 (38%), Gaps = 36/235 (15%)
Query: 44 PAGPLGATATRGMLPPGP---------PPPGPHQFGQNGAHATGHPPQRFPGPPPVNNVA 94
P +G RG + PGP PPP PHQ Q PPQ+ PPP
Sbjct: 34 PPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQ------PPPQQ---PPPQQPPP 84
Query: 95 SSHAPY-QPSAQSSYPGPISTSSVTQLGSQLSAMQINSYGSGMAPPSQGPPGPLSATSLQ 153
P+ QP Q P P Q S+ + + G G AP P S+
Sbjct: 85 HQPPPHPQPHQQQQPPPP----------PQDSSKPVVAQGPGPAPGVGSAPPASSSAPPA 134
Query: 154 TPPRPPQPSILQPGSQVLPPPPTTLNGPGASP-----LPLPMYRPDGLSGPPPPNAQYQP 208
TPP P PG PPP T PGA P +P P PPPP A P
Sbjct: 135 TPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGP 194
Query: 209 PPLPGQTLGAGYPP-QQANSGPQMAGAQ-LSYPGGFPGGPAQMAGPPQPQKKLDP 261
P P Q G G P + GP+ G LS PGG P P + G P+ ++ P
Sbjct: 195 GPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHP 249
Score = 72.0 bits (175), Expect = 3e-12
Identities = 80/286 (27%), Positives = 105/286 (36%), Gaps = 40/286 (13%)
Query: 40 GMMKPAGPLG-ATATRGMLPPGPPPPGPHQFGQNGAHATGHPPQRFPG--PPPVNNVASS 96
G+ + GP+G G PP PPPP PHQ Q PPQ+ P PPP
Sbjct: 39 GLNQNRGPMGPGPGQSGPKPPIPPPP-PHQ-QQQQPPPQQPPPQQPPPHQPPPHPQPHQQ 96
Query: 97 HAPYQPSAQSSYP----GPISTSSVTQLGSQLSAMQINSYGSGMAPPSQGP-------PG 145
P P SS P GP V S+ + + APP GP P
Sbjct: 97 QQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPA 156
Query: 146 PLSATSLQTPPRPPQPSI--LQPGSQVLPPPPTTLNGPGASPLPLPMYRPDGLSGPPPPN 203
SA PP PP + P + PPPP + GPG P P P G G P
Sbjct: 157 VTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGP--GPGGPKGGKMPG 214
Query: 204 AQYQPPPLPGQTLGAGYPPQQANSGPQMAGAQLSYP--------GGFPGGPAQMAGPPQP 255
+P PG + G+P G + G + +P G PGGP G
Sbjct: 215 GP-KPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPPPGGP----GGRSE 269
Query: 256 QKKLDPDSIPSPIQVIENDRASRGGQVYATNTR---GQIPPLVTTD 298
+K D + + + ++ G + Y R G +P +T D
Sbjct: 270 EKISDSEGFKANLSLLRRP----GEKTYTQRCRLFVGNLPADITED 311
Score = 62.4 bits (150), Expect = 2e-09
Identities = 65/214 (30%), Positives = 71/214 (33%), Gaps = 32/214 (14%)
Query: 65 GPHQFGQNGAHATGHPPQRFPGPPPVNNVASSHAPYQPS-AQSSYPGPISTSSVTQLGSQ 123
G H+ G G H F PPP + + P P QS PI Q Q
Sbjct: 15 GFHRRGGGGGRGGLHD---FRSPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQ 71
Query: 124 LSAMQINSYGSGMAPPSQGPPGPLSATSLQTPPRP-------------PQPSI--LQPGS 168
Q PP Q PP P Q PP P P P + P S
Sbjct: 72 PPPQQPPPQ---QPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPAS 128
Query: 169 QVLPP--PPTTLNGPGASPLPLPMYRPDGLSGP---PPPNAQYQPPPLPGQTLGAGYPPQ 223
PP PPT+ PG+ P P P P S P PPP P G PP
Sbjct: 129 SSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPP 188
Query: 224 QANSGPQMAGAQLSYPGG-----FPGGPAQMAGP 252
A GP Q PGG PGGP GP
Sbjct: 189 AAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGP 222
Score = 43.1 bits (100), Expect = 0.001
Identities = 40/136 (29%), Positives = 48/136 (35%), Gaps = 27/136 (19%)
Query: 138 PPSQG---PPGPLSATSLQTPPRPPQPSILQPGSQVLPPPPTTLNGPGASPLPLPMYRPD 194
PP G GP+ Q+ P+PP + PPPP P P P
Sbjct: 35 PPGMGLNQNRGPMGPGPGQSGPKPP----------IPPPPPHQQQQQPPPQQPPPQQPPP 84
Query: 195 GLSGP-PPPNAQYQPPPLPGQTLGAGYPPQQANSGPQMAGAQLSYPGGFPGGPAQMAGPP 253
P P P+ Q QPP PP Q +S P +A PG PA + PP
Sbjct: 85 HQPPPHPQPHQQQQPP-----------PPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPP 133
Query: 254 --QPQKKLDPDSIPSP 267
P P S P P
Sbjct: 134 ATPPTSGAPPGSGPGP 149
Score = 42.4 bits (98), Expect = 0.002
Identities = 55/194 (28%), Positives = 64/194 (32%), Gaps = 56/194 (28%)
Query: 15 PQPGIGLSPPHYGHYGDPSHTASPTGMMKPAGPLGATATRG----MLPPGPPPPGPHQFG 70
P PG+G +PP P T +G +GP G T T PPG PPP P G
Sbjct: 117 PAPGVGSAPP--ASSSAPPATPPTSGAPPGSGP-GPTPTPPPAVTSAPPGAPPPTPPSSG 173
Query: 71 QNGAHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGSQLSAMQIN 130
T P P PPP ++ PGP
Sbjct: 174 V----PTTPPQAGGPPPPP----------------AAVPGP------------------- 194
Query: 131 SYGSGMAPPSQGP-PGPLSATSLQTPPRP-PQPSILQPGSQVLPPPPTTLNG-PGASPLP 187
G G P QGP PG + P+P P + PG P PP G P
Sbjct: 195 --GPG---PKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGH--PKPPHRGGGEPRGGRQH 247
Query: 188 LPMYRPDGLSGPPP 201
P Y GPPP
Sbjct: 248 HPPYHQQHHQGPPP 261
Score = 39.7 bits (91), Expect = 0.015
Identities = 30/102 (29%), Positives = 35/102 (34%), Gaps = 7/102 (6%)
Query: 10 PPYSQPQPGIGLSPPHYGHYGDPSHTASPTGMMKPAGPLGATATRGMLPPGPPPPGPHQF 69
PP + P G+ +PP G P G GP G +P GP P G
Sbjct: 165 PPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGL 224
Query: 70 GQNGAHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGP 111
G H PP R G P H PY Q + GP
Sbjct: 225 STPGGHP--KPPHRGGGEP--RGGRQHHPPYH---QQHHQGP 259
Score = 38.1 bits (87), Expect = 0.043
Identities = 28/86 (32%), Positives = 33/86 (38%), Gaps = 8/86 (9%)
Query: 8 ATPPYSQPQPGIGLSPPHYGHYGDPSHTASPTGMMKPAGPLGATATRGMLPPGPPP---- 63
ATPP S PG G P P+ T++P G P P T GPPP
Sbjct: 134 ATPPTSGAPPGSGPGPTPTP---PPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAA 190
Query: 64 -PGPHQFGQNGAHATGHPPQRFPGPP 88
PGP + G G + PG P
Sbjct: 191 VPGPGPGPKQGPGPGGPKGGKMPGGP 216
>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
Length = 424
Score = 81.6 bits (200), Expect = 3e-15
Identities = 85/262 (32%), Positives = 98/262 (37%), Gaps = 64/262 (24%)
Query: 8 ATPPYSQPQP-----GIGLSPPHYGHYGDPSHTASPTGMMKPAGPLGATATRGMLPPGPP 62
A PP S P P G GL PP G P P G P P G+ P PP
Sbjct: 214 APPPPSAPNPVVSSLGSGLPPP-----GMP-----PPGSFPPPVPPPGALPPGIPPAMPP 263
Query: 63 PPGPHQFGQNGAHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGS 122
PP P A GH GPP + H P S+P P + G
Sbjct: 264 PPMP-------PGAAGH------GPPSAGTPGAGH----PGHGHSHPHPFPPGGMPHPG- 305
Query: 123 QLSAMQINSYG-SGMAPPSQGPPGPLSATSLQTPPRPPQPSILQPG--SQVLPPPPTTLN 179
+S MQ+ +G G+ P GPPG + Q PPRPP P + PG +PP
Sbjct: 306 -MSQMQLAHHGPHGLGHPHAGPPG----SGGQPPPRPP-PGMPHPGPPPMGMPPRGPPFG 359
Query: 180 GPGASPLPLPMYRPDGLSGPPP--PNAQYQPPPLPGQTLGAGYPPQQANSGPQMAGAQLS 237
P P P+P P G+ GPPP P Y PP P PP GP L
Sbjct: 360 SPMGHPGPMP---PHGMRGPPPLMPPHGYTGPPRP--------PPYGYQRGP------LP 402
Query: 238 YPGGFPGGPAQMAGP---PQPQ 256
P P P GP P PQ
Sbjct: 403 PPRPTPRPPVPPRGPLRGPLPQ 424
Score = 53.1 bits (126), Expect = 1e-06
Identities = 42/138 (30%), Positives = 52/138 (37%), Gaps = 11/138 (7%)
Query: 129 INSYGSGMAPPSQGPPGPLSATSLQTPPRPPQPSILQPG-SQVLPPPPTTLNGPGASPLP 187
++S GSG+ PP PPG PP P P L PG +PPPP PGA+
Sbjct: 225 VSSLGSGLPPPGMPPPGSF-------PPPVPPPGALPPGIPPAMPPPPMP---PGAAGHG 274
Query: 188 LPMYRPDGLSGPPPPNAQYQPPPLPGQTLGAGYPPQQANSGPQMAGAQLSYPGGFPGGPA 247
P G P ++ P P G Q A+ GP G + P G G P
Sbjct: 275 PPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPP 334
Query: 248 QMAGPPQPQKKLDPDSIP 265
P P P +P
Sbjct: 335 PRPPPGMPHPGPPPMGMP 352
Score = 41.2 bits (95), Expect = 0.005
Identities = 39/115 (33%), Positives = 45/115 (39%), Gaps = 29/115 (25%)
Query: 155 PPRPPQPSILQPGSQVLPP--PPTTLNGPGASPLPLPMYRPDGLSGPPPPNAQYQPPPLP 212
PP P P + GS + PP PP PG+ P P+P P G P P A PPP+P
Sbjct: 217 PPSAPNPVVSSLGSGLPPPGMPP-----PGSFPPPVP---PPGALPPGIPPAM-PPPPMP 267
Query: 213 GQTLGAGYPPQQANSGPQMAGAQLSYPGGFPGGPAQMAGPPQPQKKLDPDSIPSP 267
P A GP AG PG G P P P P +P P
Sbjct: 268 ---------PGAAGHGPPSAGT----PGA--GHPGHGHSHPHP---FPPGGMPHP 304
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 81.6 bits (200), Expect = 3e-15
Identities = 89/269 (33%), Positives = 100/269 (37%), Gaps = 50/269 (18%)
Query: 11 PYSQPQPGIGLSPPHYGHYGDPSHTA-SPTGMMKPAGPLGATATRGMLPPGPPPPGPHQF 69
P P PG PP G D S + SP G KP GP G P GPPPP
Sbjct: 68 PQGPPPPGKPQGPPPQG---DKSRSPRSPPG--KPQGP---PPQGGNQPQGPPPPPGKPQ 119
Query: 70 G---QNGAHATGHPPQRFP-GPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGSQLS 125
G Q G G PP P GPPP + S +P P + P P Q G+Q
Sbjct: 120 GPPPQGGNRPQGPPPPGKPQGPPPQGD--KSRSPRSPPGKPQGPPP-------QGGNQ-- 168
Query: 126 AMQINSYGSGMAPP---SQGPPGPLSATSLQTPPRPPQPSILQPGSQVLPPPPTTLNGPG 182
G PP QGPP P Q PP P +P PPP +
Sbjct: 169 -------PQGPPPPPGKPQGPP-PQGGKKPQGPPPPGKPQ--------GPPPQGDKSRSS 212
Query: 183 ASPLPLPMYRP----DGLSGPPPPNAQYQPPPLPGQTLGAGYPPQQANSGPQMAGAQLSY 238
SP P P + GPPPP + Q PP G G PP GP G S
Sbjct: 213 QSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQ 272
Query: 239 PGGFPGGPAQMAGPPQPQKKLDPDSIPSP 267
P G Q GPPQ Q+ +P P P
Sbjct: 273 SARSPPGKPQ--GPPQ-QEGNNPQGPPPP 298
Score = 78.6 bits (192), Expect = 3e-14
Identities = 79/257 (30%), Positives = 96/257 (37%), Gaps = 41/257 (15%)
Query: 31 DPSHTASPTGMMKPAGPLGATATRGMLPPGPPPPGPHQFG---QNGAHATGHPPQRFP-G 86
D S SP+ + P G + G P GPPPP G Q G G PP P G
Sbjct: 22 DVSQEESPS--LIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG 79
Query: 87 PPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGSQLSAMQINSYGSGMAPPSQG---- 142
PPP + S +P P + P P Q G+Q G PP QG
Sbjct: 80 PPPQGD--KSRSPRSPPGKPQGPPP-------QGGNQPQGPP-PPPGKPQGPPPQGGNRP 129
Query: 143 ------------PPGPLSATSLQTPPRPPQPSILQPGSQVLPPPPTTLNGPGASPLPLPM 190
PP + S ++PP PQ Q G+Q PPP G P P
Sbjct: 130 QGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPP--GKPQGPPPQGG 187
Query: 191 YRPDGLSGPPPPNAQYQPPPLPGQTLGAGYPPQQANSGPQMAGAQLSYPGGFPGGPAQMA 250
+P GPPPP PPP ++ + PP + P G Q P G P P +
Sbjct: 188 KKP---QGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQ---PQGPPPPPGKPQ 241
Query: 251 GPPQPQKKLDPDSIPSP 267
GPP PQ P P P
Sbjct: 242 GPP-PQGGNKPQGPPPP 257
Score = 63.5 bits (153), Expect = 1e-09
Identities = 78/230 (33%), Positives = 83/230 (36%), Gaps = 44/230 (19%)
Query: 11 PYSQPQPGIGLSPPHYGHYGDPSHTA-SPTGMMKPAGPLGATATRGMLPPGPPPPGPHQF 69
P P PG PP G D S + SP G KP GP G P GPPPP
Sbjct: 129 PQGPPPPGKPQGPPPQG---DKSRSPRSPPG--KPQGP---PPQGGNQPQGPPPPPGKPQ 180
Query: 70 G---QNGAHATGHPPQRFP-GPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGSQLS 125
G Q G G PP P GPPP + S + P + P P Q G+Q
Sbjct: 181 GPPPQGGKKPQGPPPPGKPQGPPPQGD--KSRSSQSPPGKPQGPPP-------QGGNQ-- 229
Query: 126 AMQINSYGSGMAPPS---QGPPGPLSATSLQTPPRP--PQPSILQPGS--QVLPPPPTTL 178
G PP QGPP P Q PP P PQ Q GS Q PP
Sbjct: 230 -------PQGPPPPPGKPQGPP-PQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKP 281
Query: 179 NGPGASPLPLPMYRPDGLSGPP-----PPNAQYQPPPLPGQTLGAGYPPQ 223
GP P P G P PP Q Q PP P Q PPQ
Sbjct: 282 QGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ 331
>gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]
Length = 1336
Score = 81.3 bits (199), Expect = 4e-15
Identities = 83/272 (30%), Positives = 105/272 (38%), Gaps = 30/272 (11%)
Query: 4 QGYVATPPYSQPQPGIGLSPPHYGHYGDPSHTA--SPTGMMKPAGPLGATATRG-MLPPG 60
QG++ P G+ +G G H P G P GP G++ +G M P G
Sbjct: 650 QGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQG 709
Query: 61 PPPPGPHQFGQNGAHATGH-PPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQ 119
PP P H Q GH PQ GPP + P P P P Q
Sbjct: 710 PPGPQGHIGPQGPPGPQGHLGPQ---GPPGTQGM---QGPPGPRGMQGPPHPHGI----Q 759
Query: 120 LGSQLSAMQINSYGSGMAPPSQGPPGPLSATSLQTPPRPPQPSILQPGSQVLPPPPTTLN 179
G +Q P SQGP L+ +Q PP P + P ++ PP +
Sbjct: 760 GGPGSQGIQ--------GPVSQGPLMGLNPRGMQGPPGPRENQGPAPQGMIMGHPPQEMR 811
Query: 180 GPGASPLPLPMYRPDGLSGPPPPNAQYQPPPLPGQTLGAGYPPQQANSGPQMAGAQLSYP 239
GP P L + P + GP PPP G LG PPQ+ GP + +Q P
Sbjct: 812 GP-HPPGGLLGHGPQEMRGPQEIRGMQGPPP-QGSMLG---PPQELR-GPPGSQSQQGPP 865
Query: 240 GGFPGGPAQ--MAGPPQPQKKLDPDSIPSPIQ 269
G G P Q M GPP PQ + +P P P Q
Sbjct: 866 QGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQ 897
Score = 75.9 bits (185), Expect = 2e-13
Identities = 84/299 (28%), Positives = 109/299 (36%), Gaps = 45/299 (15%)
Query: 12 YSQPQPGIGLSPPHYGHYGDPSHTASPTGMMKPAGPLGATATRGMLPPGPP--PPGPHQF 69
+ QP P + P + G P P G +P GP G M P GPP G
Sbjct: 601 FQQPHPSQQM-PMNMAQMGPPG----PQGQFRPPGPQGQ-----MGPQGPPLHQGGGGPQ 650
Query: 70 GQNGAHATGHPPQRFPGPPPVN---NVASSHAPYQPSAQSSYPGPISTSSVT-QLGSQLS 125
G G PPQ P P ++ + P+ P PGP +S +G Q
Sbjct: 651 GFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGP 710
Query: 126 AMQINSYGSGMAPPSQ---GPPGPLSATSLQTPP------RPPQPSILQ--PGSQVLPPP 174
G P Q GP GP +Q PP PP P +Q PGSQ + P
Sbjct: 711 PGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGP 770
Query: 175 PTTLNGPGASPLPLPMYRPDGLSGPPPPNAQYQPPPLPGQTLGAGYPPQQANSGPQMAGA 234
S PL P G+ GPP P P P Q + G+PPQ+ GP G
Sbjct: 771 --------VSQGPLMGLNPRGMQGPPGPRENQGPAP---QGMIMGHPPQEMR-GPHPPGG 818
Query: 235 QLSYPGGFPGGPAQMAGPPQPQKKLDPDSIPSPIQVIENDRASRGGQVYATNTRGQIPP 293
L + GP +M GP + + P S + + R G Q +G + P
Sbjct: 819 LLGH------GPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPPQGSLGP 871
Score = 54.3 bits (129), Expect = 6e-07
Identities = 57/191 (29%), Positives = 68/191 (35%), Gaps = 36/191 (18%)
Query: 81 PQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGSQLSAMQINSYGSGMAPPS 140
PQ FPG P++ + PS Q ++ Q+G Q G
Sbjct: 585 PQPFPGQGPMSQIPQGFQQPHPSQQ-------MPMNMAQMGPPGPQGQFRPPGPQGQMGP 637
Query: 141 QGPP------GPLSATSLQTPPRPPQPSILQPGSQVLPPPPTTLNGP-GASPLPLPMYRP 193
QGPP GP Q P PPQ P P ++GP G P P + P
Sbjct: 638 QGPPLHQGGGGPQGFMGPQGPQGPPQGL----------PRPQDMHGPQGMQRHPGP-HGP 686
Query: 194 DGLSGPPPPNAQYQP--------PPLPGQTLGAGYPP-QQANSGPQMAGAQLSYPGGFPG 244
G GPP P P PP P +G PP Q + GPQ G P
Sbjct: 687 LGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQG--PP 744
Query: 245 GPAQMAGPPQP 255
GP M GPP P
Sbjct: 745 GPRGMQGPPHP 755
Score = 48.1 bits (113), Expect = 4e-05
Identities = 51/164 (31%), Positives = 54/164 (32%), Gaps = 20/164 (12%)
Query: 135 GMAPPSQGPPG-PLSATSLQTPPRPPQPSILQPGSQVLPPPPTTLNGPGASPLPLPMYRP 193
G P SQ P G S Q P Q P Q PP P GP PL P
Sbjct: 590 GQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGP 649
Query: 194 DGLSGPPPPNAQYQPPPLPGQTLG----------------AGYPPQQANSGPQMAGAQLS 237
G GP P Q P P G G P Q +SGPQ
Sbjct: 650 QGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQG 709
Query: 238 YPGGFPGGPAQMAGPPQPQKKLDPDSIPSPIQVIENDRASRGGQ 281
PG P G GPP PQ L P P Q ++ RG Q
Sbjct: 710 PPG--PQGHIGPQGPPGPQGHLGPQG-PPGTQGMQGPPGPRGMQ 750
Score = 47.4 bits (111), Expect = 7e-05
Identities = 75/301 (24%), Positives = 92/301 (30%), Gaps = 76/301 (25%)
Query: 10 PPYSQ-----PQPGIGLSPPH-YGHYGDPSHTASPTGMMKPA--GPLGATATRGMLPPGP 61
PP +Q P P PPH +G G P G+ P GPL RGM GP
Sbjct: 734 PPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQ----GIQGPVSQGPLMGLNPRGM--QGP 787
Query: 62 PPPGPHQFGQNGAHATGHPPQRFPGPPPVNNVASSHAPYQ------------PSAQSSYP 109
P P +Q GHPPQ GP P + H P + P Q S
Sbjct: 788 PGPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLG-HGPQEMRGPQEIRGMQGPPPQGSML 846
Query: 110 GPIST-----SSVTQLGSQLSAMQINSYGSGMAPPS------------------------ 140
GP S +Q G ++ G PP
Sbjct: 847 GPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQK 906
Query: 141 -----QGPPGPLSATSLQTPPRPPQPSILQPGSQVLPPPPTTLNGPGASPLPLPMYRPDG 195
GP P + T P P P + Q G+Q PP GPG P+
Sbjct: 907 TPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQGPG----------PNK 956
Query: 196 LSGPPPPNAQYQPPPLPGQTLGAGYPPQQANSGPQMAGAQLSYP----GGFPGGPAQMAG 251
PPN + P + +G P GP G P G P P +
Sbjct: 957 GDSRGPPN-HHMGPMSERRHEQSGGPEHGPERGPFRGGQDCRGPPDRRGPHPDFPDDFSR 1015
Query: 252 P 252
P
Sbjct: 1016 P 1016
Score = 45.1 bits (105), Expect = 4e-04
Identities = 44/127 (34%), Positives = 48/127 (37%), Gaps = 30/127 (23%)
Query: 169 QVLPPPP--TTLNGPGASPLPLPMYR-PDGLS---------------GPPPPNAQYQPPP 210
Q+ PPP T L GP P PM + P G GPP P Q++PP
Sbjct: 571 QIQPPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPG 630
Query: 211 LPGQTLGAGYPPQQANSGPQ-MAGAQLSYPGGFPGG---PAQMAGP------PQPQKKLD 260
GQ G P Q GPQ G Q P G P G P M GP P P L
Sbjct: 631 PQGQMGPQGPPLHQGGGGPQGFMGPQ--GPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLG 688
Query: 261 PDSIPSP 267
P P P
Sbjct: 689 PQGPPGP 695
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 79.0 bits (193), Expect = 2e-14
Identities = 88/287 (30%), Positives = 103/287 (35%), Gaps = 69/287 (24%)
Query: 4 QGYVATPPYSQPQPGIGLSPPHYGHYGDPSHTASPTGMMKPAGPLGATATRGMLPPGPPP 63
QG PP P PG G+ PP P + P PL +PP PP
Sbjct: 903 QGTEMLPPPPPPLPGAGIPPP----------PPLPGAGILPLPPLPGAG----IPPPPPL 948
Query: 64 PGPHQFGQNGAHATGHPPQRFPG-----PPPVNNVASSHAPYQPSAQSSYPGPISTSSVT 118
PG A PP PG PPP+ P P A P P+ + +
Sbjct: 949 PG----------AAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 998
Query: 119 QLGSQLSAMQINSYGSGMAPPSQG----PPGPLSATSLQTPPR------PPQPSILQPGS 168
+ G PP G PP PL + PP PP P + PG+
Sbjct: 999 ------PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL--PGA 1050
Query: 169 QVLPPPPTTLNGPGASPLPLPMYRPDGLSGPPP-PNAQY-QPPPLPGQTLGAGYPPQQAN 226
+ PPPP PGA P P G+ PPP P A PPPLP GAG PP
Sbjct: 1051 GIPPPPPL----PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP----GAGIPPPPPL 1102
Query: 227 SG------PQMAGAQLSYPGGFPGGPAQMAGPPQPQKKLDPDSIPSP 267
G P + GA + P PG AG P P L IP P
Sbjct: 1103 PGVGIPPPPPLPGAGIPPPPPLPG-----AGIP-PPPPLPGAGIPPP 1143
Score = 77.4 bits (189), Expect = 6e-14
Identities = 80/232 (34%), Positives = 94/232 (40%), Gaps = 56/232 (24%)
Query: 80 PPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGSQLSAMQINSY------- 132
P Q PPP ++ S QP +Q P IST T +S+ NS
Sbjct: 803 PTQSISQPPPPPSLLWSAGQGQPGSQP--PHSISTEFQTSHEHSVSSAFKNSCNIPSPPP 860
Query: 133 -----------GSGMAPPSQGPPGPLSATSLQTPPRP--PQPSILQPGSQVLPPPPTTLN 179
G GM PP PP PL ++ T P PQP LQ G+++LPPPP L
Sbjct: 861 LPCTESSSSMPGLGMVPP---PPPPLPGMTVPTLPSTAIPQPPPLQ-GTEMLPPPPPPLP 916
Query: 180 G---------PGASPLPLPMYRPDGLSGPPP-PNAQY-QPPPLPGQTL-------GAGYP 221
G PGA LPLP G+ PPP P A PPPLPG + GAG P
Sbjct: 917 GAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIP 976
Query: 222 PQQANSGPQMAGAQLSYPGGFPGG------PAQMAGPPQPQKKLDPDSIPSP 267
P P + GA + P PG P AG P P L IP P
Sbjct: 977 PP-----PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP-PPPPLPGAGIPPP 1022
Score = 76.3 bits (186), Expect = 1e-13
Identities = 84/282 (29%), Positives = 100/282 (35%), Gaps = 52/282 (18%)
Query: 5 GYVATPPYSQPQPGIGLSPPHYGHYGDPSHTASPTGMMKPAGPLGATATRGMLPPGPPPP 64
G PP P GI L PP G G P P + P PL +PP PP P
Sbjct: 950 GAAIPPPPPLPGAGIPLPPPLPGA-GIPPPPPLPGAGIPPPPPLPGAG----IPPPPPLP 1004
Query: 65 GPHQFGQNGAHATGHPPQRFPG-----PPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQ 119
G A PP PG PPP+ P P A P P+ + +
Sbjct: 1005 G----------AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1054
Query: 120 LGSQLSAMQINSYGSGMAPPSQG----PPGPLSATSLQTPPR------PPQPSILQPGSQ 169
+ G PP G PP PL + PP PP P + PG
Sbjct: 1055 ------PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL--PGVG 1106
Query: 170 VLPPPPTTLNGPGASPLPLPMYRPDGLSGPPPPNAQYQPPPLPGQTLGAGYPPQQANSG- 228
+ PPPP PGA P P G+ PPP PPP P +G PP +G
Sbjct: 1107 IPPPPPL----PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGI 1162
Query: 229 ---PQMAGAQLSYPGGFPGGPAQMAGPPQPQKKLDPDSIPSP 267
P + GA + P PG + PP P L IP P
Sbjct: 1163 PPPPPLPGAGIPPPPPLPG----VGIPPPP--PLPGVGIPPP 1198
Score = 76.3 bits (186), Expect = 1e-13
Identities = 85/283 (30%), Positives = 100/283 (35%), Gaps = 49/283 (17%)
Query: 11 PYSQPQPGIGLSPPH-YGHYGDPSHTASPTGMMKPAGPLGATATRGMLPPGPPPPG---P 66
P P PG G+ PP G P P + P PL +PP PP PG P
Sbjct: 976 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG----IPPPPPLPGAGIP 1031
Query: 67 HQFGQNGAHATGHPP---QRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGSQ 123
GA PP P PPP+ P P A P P+ + +
Sbjct: 1032 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP---- 1087
Query: 124 LSAMQINSYGSGMAPPSQG----PPGPLSATSLQTPPR------PPQPSILQPGSQVLPP 173
+ G PP G PP PL + PP PP P + PG+ + PP
Sbjct: 1088 --PPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL--PGAGIPPP 1143
Query: 174 PPTTLNG-------PGASPLPLPMYRPDGLSGPPPPNAQYQPPPLPGQTLGAGYPPQQAN 226
PP G PGA P P G+ PPP PPP P G G PP
Sbjct: 1144 PPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLP--GVGIPPP--- 1198
Query: 227 SGPQMAGAQLSYPGGFPGGPAQMAGPPQPQKKLDP--DSIPSP 267
P + GA + P PG M PP P L P IP P
Sbjct: 1199 --PPLPGAGIPPPPPLPG----MGIPPAPAPPLPPPGTGIPPP 1235
Score = 74.3 bits (181), Expect = 5e-13
Identities = 78/249 (31%), Positives = 94/249 (37%), Gaps = 59/249 (23%)
Query: 55 GMLPPGPPP-PG-----------PHQFGQNGAHATGHPPQRFPG-----PPPVNNVASSH 97
GM+PP PPP PG P G PP PG PPP+
Sbjct: 874 GMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILP 933
Query: 98 APYQPSAQSSYPGPISTSSVTQLGSQLSAMQINSYGSGMAPPSQG----PPGPLSATSLQ 153
P P A P P+ +++ + G + PP G PP PL +
Sbjct: 934 LPPLPGAGIPPPPPLPGAAIP------PPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIP 987
Query: 154 TPPR------PPQPSILQPGSQVLPPPPTTLNGPGASPLPLPMYRPDGLSGPPP-PNAQY 206
PP PP P + PG+ + PPPP PGA P P G+ PPP P A
Sbjct: 988 PPPPLPGAGIPPPPPL--PGAGIPPPPPL----PGAGIPPPPPLPGAGIPPPPPLPGAGI 1041
Query: 207 -QPPPLPGQTL-------GAGYPPQQANSGPQMAGAQLSYPGGFPGGPAQMAGPPQPQKK 258
PPPLPG + GAG PP P + GA + P PG AG P P
Sbjct: 1042 PPPPPLPGAGIPPPPPLPGAGIPPP-----PPLPGAGIPPPPPLPG-----AGIP-PPPP 1090
Query: 259 LDPDSIPSP 267
L IP P
Sbjct: 1091 LPGAGIPPP 1099
Score = 73.6 bits (179), Expect = 9e-13
Identities = 70/225 (31%), Positives = 80/225 (35%), Gaps = 41/225 (18%)
Query: 11 PYSQPQPGIGLSPPH-YGHYGDPSHTASPTGMMKPAGPLGATATRGMLPPGPPPPG---P 66
P P PG G+ PP G P P + P PL +PP PP PG P
Sbjct: 1064 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVG----IPPPPPLPGAGIP 1119
Query: 67 HQFGQNGAHATGHPP---QRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGSQ 123
GA PP P PPP+ V P P A P P+
Sbjct: 1120 PPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLP---------- 1169
Query: 124 LSAMQINSYGSGMAPPSQGPPGPLSATSLQTPPRPPQPSILQPGSQVLP----PPPTTLN 179
G+G+ PP PP P + PP PP P + P LP PPP L
Sbjct: 1170 ---------GAGIPPP---PPLP----GVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLP 1213
Query: 180 GPGASPLPLPMYRPDGLSGPPPPNAQYQPPPLPGQTLGAGYPPQQ 224
G G P P P P G PPPP PPL Q + P Q
Sbjct: 1214 GMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQ 1258
Score = 67.4 bits (163), Expect = 7e-11
Identities = 73/244 (29%), Positives = 87/244 (35%), Gaps = 41/244 (16%)
Query: 11 PYSQPQPGIGLSPPH-YGHYGDPSHTASPTGMMKPAGPLGATATRGMLPPGPPPPG---P 66
P P PG G+ PP G P P + P PL +PP PP PG P
Sbjct: 1020 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG----IPPPPPLPGAGIP 1075
Query: 67 HQFGQNGAHATGHPP---QRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGSQ 123
GA PP P PPP+ V P P A P P+ + +
Sbjct: 1076 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1135
Query: 124 LSAMQINSYGSGMAPPSQ------GPPGPLSATSLQTPPR------PPQPSILQPGSQVL 171
G+G+ PP PP PL + PP PP P + PG +
Sbjct: 1136 P--------GAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL--PGVGIP 1185
Query: 172 PPPPTTLNGPGASPLPLPMYRPDGLSGPPP-PNAQYQP---PPLPGQTLGAGYPPQQANS 227
PPPP PG P P G+ PPP P P PPLP G PP S
Sbjct: 1186 PPPPL----PGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVS 1241
Query: 228 GPQM 231
GP +
Sbjct: 1242 GPPL 1245
Score = 33.1 bits (74), Expect = 1.4
Identities = 33/107 (30%), Positives = 38/107 (35%), Gaps = 18/107 (16%)
Query: 11 PYSQPQPGIGLSPPH-YGHYGDPSHTASPTGMMKPAGPL-GATATRGMLPPGPPPPGPHQ 68
P P PG+G+ PP G P P + P PL G PP PPP
Sbjct: 1174 PPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPP----- 1228
Query: 69 FGQNGAHATGHPPQRF---PGPPPVNNVASSHAPYQPSAQSSYPGPI 112
TG PP GPP + V SS P P P P+
Sbjct: 1229 -------GTGIPPPPLLPVSGPPLLPQVGSSTLP-TPQVCGFLPPPL 1267
Score = 32.0 bits (71), Expect = 3.1
Identities = 45/179 (25%), Positives = 60/179 (33%), Gaps = 30/179 (16%)
Query: 102 PSAQSSYPGPISTSSVTQLGSQLSAMQINSYGSGMAPPSQGPPGPLSATS-----LQTPP 156
P+A S PG LG S G+G AP S LSA S L P
Sbjct: 236 PTAVSPQPGAFLGLDRFLLGP--------SGGAGEAPGSPDTEQALSALSDLPESLAAEP 287
Query: 157 RPPQPSILQPGSQVLPPP------PTTLNGPGASPLPLPMYRP-DGLSGPPPPNA----- 204
R PQ G V P P + P ++ P P P + +G P A
Sbjct: 288 REPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDE 347
Query: 205 ---QYQPPPLPGQTLGAGYPPQQANSGPQMAGAQLSYPGGFPGGP--AQMAGPPQPQKK 258
+ P + G + P+ PQ G + P P A + G P P ++
Sbjct: 348 EGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGPDAPAAASLPGSPAPSQR 406
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 75.5 bits (184), Expect = 2e-13
Identities = 86/293 (29%), Positives = 106/293 (36%), Gaps = 55/293 (18%)
Query: 11 PYSQPQPGIGLSPPHYGHYGD----PSHTA-------SPTGMMKPAGPLGATATRGMLPP 59
P P L PP G G P+ A +P G KPAGP A G P
Sbjct: 116 PAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAG---P 172
Query: 60 GPPP-PGPHQFGQNGAHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVT 118
GP P PGP G A Q G + N SH P+ GP + +
Sbjct: 173 GPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLN---SHHAAAPAVSLVNNGPAALLPLP 229
Query: 119 QLGSQLSAMQINSYGSGMAPPSQGPPGP-----LSATSLQTPPRPPQPSIL--QPG---- 167
+ + + +Q + APP+ P P +A + PP PP P+ L PG
Sbjct: 230 KPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAG 289
Query: 168 ----SQVLPPPPTTLNG--PGASPLPLPMY-RPDGLSGPPPPNAQYQPP----------- 209
+ +PPP NG GA+P P P P G+SG P P A P
Sbjct: 290 PPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKR 349
Query: 210 -----PLPGQTLGAGYPPQQANS---GPQMAGAQLSYPGGFPGGPAQMAGPPQ 254
P QTL A P A S GP M GA S P P G P+
Sbjct: 350 VVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPK 402
Score = 59.3 bits (142), Expect = 2e-08
Identities = 77/253 (30%), Positives = 91/253 (35%), Gaps = 35/253 (13%)
Query: 27 GHYGDPSHTASPTGMMKPAGPLGATATRGMLPPGPPPPGPHQFGQNGAHATGHPPQRFP- 85
G G+ + SP G AGP P PPP G + G G G P R P
Sbjct: 56 GALGNHVVSGSPAGAAG-AGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPL 114
Query: 86 ---GP--------PPVNNVASSHAPYQPSAQ-SSYPGPISTSSVTQLG-SQLSAMQINSY 132
GP PP A S AP +A ++ P P G + L+A
Sbjct: 115 VPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGP 174
Query: 133 GSGMAP-PSQGPPGPLSATSLQTPPRPPQPSILQPGSQVLPPPPTTLNGPGA-SPLPLP- 189
G G P P GP P + QT ++L P NGP A PLP P
Sbjct: 175 GPGPGPGPGPGPGKPAGPGAAQT--LNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPA 232
Query: 190 -----MYRPD--GLSGPPPPNAQYQPPPLPGQTLGAGYPPQQANSGPQMAGAQLSYPGGF 242
+ P G + PP P A PP P A PP P A A L+ P G
Sbjct: 233 APGTVIQTPPFVGAAAPPAPAAP-SPPAAPAPAAPAAAPPP-----PPPAPATLARPPGH 286
Query: 243 PGGP--AQMAGPP 253
P GP A A PP
Sbjct: 287 PAGPPTAAPAVPP 299
Score = 50.4 bits (119), Expect = 8e-06
Identities = 50/171 (29%), Positives = 66/171 (38%), Gaps = 37/171 (21%)
Query: 98 APYQPSAQSSYPGPISTSSVTQLGSQLSAMQINSYGSGMAPPSQGPPGPLSATSLQTPPR 157
AP P +++ G + V+ GS A G+G A P++G PG P
Sbjct: 44 APRTPEVRAAAAGALGNHVVS--GSPAGAA-----GAGPAAPAEGAPG--------AAPE 88
Query: 158 PPQPSILQPGSQVLPPPPTTLNGPGASPLPLPMYRPDGLSGPPPPNAQYQPPPLPGQTLG 217
PP +PG GP P P RP +GP PP A+ +PPP
Sbjct: 89 PPPAGRARPGG----------GGPQRPGPPSPR-RPLVPAGPAPPAAKLRPPPEGSAGSC 137
Query: 218 AGYPPQQA-NSGPQMAGAQLSYPGGFPGGPAQMAGPPQPQKKLDPDSIPSP 267
A P A +GP+ A P GPA+ AGP + P P P
Sbjct: 138 APVPAAAAVAAGPEPA----------PAGPAKPAGPAALAARAGPGPGPGP 178
Score = 49.3 bits (116), Expect = 2e-05
Identities = 55/216 (25%), Positives = 67/216 (31%), Gaps = 40/216 (18%)
Query: 5 GYVATPPYSQPQ-PGIGL-SPPHYGHYGDPSHTA-SPTGMMKPAGPLGATATRGMLPPGP 61
G A P +P PG + +PP G P+ A SP PA P A P P
Sbjct: 221 GPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAA--------PPP 272
Query: 62 PPPGPHQFGQNGAHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLG 121
PPP P + H G P PPP A P+ + GP
Sbjct: 273 PPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGV------- 325
Query: 122 SQLSAMQINSYGSGMAPPSQGPPGPLSATSLQTPPRPPQPSILQPGSQVLPPPPTTLNGP 181
SG P P ++P R Q + PP TL
Sbjct: 326 ------------SGQPGPGAAAAAPAPGVKAESPKRVVQAA---------PPAAQTLAAS 364
Query: 182 GASPLPLPMYRPDGLSGPPPPNAQYQPPPLPGQTLG 217
G + M + G P A PPP PG G
Sbjct: 365 GPASTAASMVIGPTMQGALPSPAAV-PPPAPGTPTG 399
Score = 35.4 bits (80), Expect = 0.28
Identities = 60/258 (23%), Positives = 82/258 (31%), Gaps = 60/258 (23%)
Query: 8 ATPPYSQPQPGIGLSPPHYGHYGDPSHTASPTGMMKPAGPLGATATRGMLP-PGPPPPGP 66
A PP P P PP GH P TA+P A G +A G P P P GP
Sbjct: 268 AAPPPPPPAPATLARPP--GHPAGPP-TAAPAVPPPAAAQNGGSA--GAAPAPAPAAGGP 322
Query: 67 H----QFGQNGAHATGHPPQRFPGP-------PPVNNVASSHAPYQ--------PSAQSS 107
Q G A A P + P PP ++ P P+ Q +
Sbjct: 323 AGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGA 382
Query: 108 YPGPIST----------------SSVTQLGSQLSAMQINSYGSGMAPP------SQGPPG 145
P P + +VTQ S+ + + + P Q P
Sbjct: 383 LPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQN 442
Query: 146 PLSATSLQTPPRP-------------PQPSILQPGSQVLPPPPTTLNGPGASPLPLPMYR 192
P + + Q PP PQ ++ Q +Q P TT+ A+P P +
Sbjct: 443 PTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQ 502
Query: 193 PDGLSGPPPPNAQYQPPP 210
+ P P Q P
Sbjct: 503 ISTVQAPGTPIIARQVTP 520
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 75.5 bits (184), Expect = 2e-13
Identities = 76/243 (31%), Positives = 87/243 (35%), Gaps = 46/243 (18%)
Query: 10 PPYSQPQPGIGLSPPHYGHYGDPSHTASPTGMMKPAGPLGATATRGMLPPGPPPPGPHQF 69
PP P PP A+ G +P GP+ AT + P P P P
Sbjct: 363 PPLPPAHPPPDRKPP----------LAAALGEAEPPGPVDATDLPKVQIPPPAHPAP--- 409
Query: 70 GQNGAHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLG----SQLS 125
H P R P PPP SSY +ST+S G S S
Sbjct: 410 ----VHQPPPLPHRPPPPPP----------------SSYMTGMSTTSSYMSGEGYQSLQS 449
Query: 126 AMQINSYGSGMAPPSQGPPGPLSATSLQTPPRPPQPSILQPGSQVLPP--PPTTLNGPGA 183
M+ G PP+ GPP L PP PP P + P + PP PP T PG
Sbjct: 450 MMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPT---PGY 506
Query: 184 SPLPLPMYRPDGLSGPP--PPNAQYQPPPLPGQTL-GAGYPPQQANSGPQMAGAQLSYPG 240
P P P Y P+ PP PP P P PG L A YPP G Q P
Sbjct: 507 PP-PPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYPPPAVPPGGQPPVPPPIPPP 565
Query: 241 GFP 243
G P
Sbjct: 566 GMP 568
Score = 52.0 bits (123), Expect = 3e-06
Identities = 58/205 (28%), Positives = 72/205 (35%), Gaps = 56/205 (27%)
Query: 10 PPYSQPQPGIGLSPPHYGHYGDPSHTASPTGMMKPAGPLGATATRGMLPPGPPPPGPHQF 69
PP S G+ + + G S + MMK GP + G LPP PP
Sbjct: 423 PPPSSYMTGMSTTSSYMSGEGYQSLQS----MMKTEGP-----SYGALPPAYGPP----- 468
Query: 70 GQNGAHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGSQLSAMQI 129
AH HP P PPP P P +S+P P
Sbjct: 469 ----AHLPYHPHVYPPNPPP---------PPVPPPPASFPPP------------------ 497
Query: 130 NSYGSGMAPPSQGPPGPLSATSLQTPPRPPQPSILQPGSQVLPP-PPTTLNGPGASPLPL 188
+ PP+ G P P + PP PP+ P + +PP PP L P AS P
Sbjct: 498 -----AIPPPTPGYPPPPPTYNPNFPPPPPR----LPPTHAVPPHPPPGLGLPPAS-YPP 547
Query: 189 PMYRPDGLSGPPPPNAQYQPPPLPG 213
P P G PPP PP+ G
Sbjct: 548 PAVPPGGQPPVPPPIPPPGMPPVGG 572
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 74.7 bits (182), Expect = 4e-13
Identities = 96/378 (25%), Positives = 127/378 (33%), Gaps = 50/378 (13%)
Query: 5 GYVATPPYSQPQPGIGLSPPHYGHYGDPSHTASPT-GMMKPAGPLGATATR----GMLPP 59
G PP P P P G P H +P ++ P P G AT PP
Sbjct: 1254 GPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPP 1313
Query: 60 GPPPPGPHQFGQNGAHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQ 119
PP P G+ T PP+ P PP V + P P+ S G +T S +
Sbjct: 1314 AATPPSP-----KGSPGTP-PPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKE 1367
Query: 120 LGSQLSAMQINSYGSGMAPPSQGPPGPLSATSLQTPP-RPPQPSILQPGSQVLPPPPTTL 178
+ +A + G M PPS P ++ +P P P+++ + P P T
Sbjct: 1368 GPTPPAATPSHKGGPAMTPPS-----PKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTR 1422
Query: 179 NG---PGASPLPLPMYRPDGLSGPPPPNAQYQPPPLPGQ----TLGAGYPPQQANSGPQM 231
G P L P P L P +A P P TL A PP
Sbjct: 1423 EGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPK 1482
Query: 232 AGAQLSYPGGFPGGPAQMAGPPQPQKKLDPDSIPSPIQVIENDRASRGGQVYATNT---- 287
A S P P PA M P P IPS + + +SR + T T
Sbjct: 1483 QVATSSSPKKAPATPAPMGAPTLPA------VIPSSPKEVPATPSSRRDPIAPTATLLSK 1536
Query: 288 ---------RGQIPPLVTTDCMIQDQGNASPRFIRCTTYCFPCTSDMA------KQAQIP 332
IPP +T + +P+ T +S A K A P
Sbjct: 1537 KTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSP 1596
Query: 333 LAAVIKPFATIPS-NESP 349
+I P T PS E+P
Sbjct: 1597 KELLIPPAVTSPSPKEAP 1614
Score = 70.5 bits (171), Expect = 8e-12
Identities = 85/304 (27%), Positives = 109/304 (35%), Gaps = 35/304 (11%)
Query: 2 SQQGYVATPPYSQPQPGIGLS-PPHYGHYGDPSHTA-SPTGMMKPAGPLGATATRGMLPP 59
S +G P + P P GL+ PPH G P+ T SP G + P GA T PP
Sbjct: 1098 SPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP 1157
Query: 60 GPPPPGPHQFGQNGAHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQ 119
P G AT PP P P A+ +P A S G +T + T
Sbjct: 1158 SP----------KGGLAT--PP---PKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP 1202
Query: 120 LGSQLSAMQINSYGSGMAPPSQGPPGPLSATSLQTPPRPPQPSILQP----GSQVLPPPP 175
S + S P+ PP P + +P P P G PPP
Sbjct: 1203 -PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPK 1261
Query: 176 TTLNGPGASPLPLPMYRPDGLSGPP---PPNAQYQPPPLPGQTLGAGYPPQQANSGPQMA 232
P A+P L GL+ PP PN PP P + A PP+ A + P
Sbjct: 1262 GAPTPPAATPPSL----KGGLATPPHKGAPNPAVVTPPSP-KGGPATSPPKGAPTPP--- 1313
Query: 233 GAQLSYPGGFPGGPAQMAGPPQPQKKLDPDSIPSPIQVIENDRASRGGQVYATNTRGQIP 292
A P G PG P P P + P S + +S+GG ++ G P
Sbjct: 1314 AATPPSPKGSPGTPPPKGAPTPP--AVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTP 1371
Query: 293 PLVT 296
P T
Sbjct: 1372 PAAT 1375
Score = 60.5 bits (145), Expect = 8e-09
Identities = 91/350 (26%), Positives = 115/350 (32%), Gaps = 35/350 (10%)
Query: 4 QGYVATP-PYSQPQPGIGLSPPHYGHYGDPSHTASPTG-MMKPAGPLGATATRGM----L 57
+G A+P P P P P G PS +PT P P G AT
Sbjct: 928 KGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPT 987
Query: 58 PPGPPPPGPHQFGQNGAHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSV 117
PP PP P G AT P + P PP V + +P A + +P ST
Sbjct: 988 PPAATPPSP-----KGGPATPSP-KGAPTPPAVTPPSPKGSP----AATPFPKGASTPP- 1036
Query: 118 TQLGSQLSAMQINSYGSGMAPP-SQGPPGPLSATSLQTPPRPPQPSILQPGSQVLPPPPT 176
+A + GS A P +G P +AT P PS+ + PP+
Sbjct: 1037 -------AATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPS 1089
Query: 177 TLNGPGASPLPLPMYRPDGLSGPPPPNAQYQPPPLPGQTLGAGYPPQQANSGPQMAGAQL 236
GP A+P P P + P P PP T A PP G
Sbjct: 1090 PKGGP-ATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPS------PKGGLAT 1142
Query: 237 SYPGGFPGGPAQMAGPPQPQKKL-DPDSIPSPIQVIENDRASRGGQVYATNTRGQIPPLV 295
P G P PA A PP P+ L P +P + +GG + P
Sbjct: 1143 PPPKGAPTTPA--ATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA 1200
Query: 296 TTDCMIQDQGNASPRFIRCTTYCFPCTSDMAKQAQIPLAAVIKPFATIPS 345
T SP+ T P + P A P AT PS
Sbjct: 1201 TPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPS 1250
Score = 55.8 bits (133), Expect = 2e-07
Identities = 71/289 (24%), Positives = 100/289 (34%), Gaps = 43/289 (14%)
Query: 27 GHYGDPSHTASPTGMMKPAGPLGATATRGMLPPGPPPPGPHQFGQNGAHATGHPPQRFPG 86
G P+ T SPT P P GA + P P PP+ P
Sbjct: 845 GSKDSPATTHSPT----PPSPKGAPTPSAVTPLSPK-------------GVTLPPKETPT 887
Query: 87 PPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGSQLSAMQINSYGS---GMAPPSQGP 143
P VN P P+ + + +++SS + + + I + S PP+ P
Sbjct: 888 PSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATP 947
Query: 144 PGPLSATSLQTP---PRPPQ---------PSILQPGSQVLPP---PPTTLNGPGASPLPL 188
P P + +P P PP P+ P PP PP+ GP A+P P
Sbjct: 948 PSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGP-ATPSPK 1006
Query: 189 PMYRPDGLSGPPPPNAQYQPPPLPGQTLGAGYPPQQANSGPQMAGAQLSYPGGFPGGPAQ 248
P ++ PP P P P GA PP P+ + A P G P PA
Sbjct: 1007 GAPTPPAVT-PPSPKGSPAATPFP---KGASTPPAATPPSPKGSPAATPLPKGAPTTPA- 1061
Query: 249 MAGPPQPQ-KKLDPDSIPSPIQVIENDRASRGGQVYATNTRGQIPPLVT 296
A P P+ P +P + +GG + +PP T
Sbjct: 1062 -ATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAAT 1109
Score = 45.4 bits (106), Expect = 3e-04
Identities = 78/339 (23%), Positives = 113/339 (33%), Gaps = 59/339 (17%)
Query: 32 PSHTASPTGMMKPAGPLGATATRGMLPPGPPPPGPHQFGQNGAHATGHPPQRFPGPPPVN 91
P +T +P + A + + LPP PPG + +H + P
Sbjct: 714 PQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKV-DGISHTSALAP---------- 762
Query: 92 NVASS--HAPYQPSAQSSYPGPISTSSVTQLGSQLSAMQINSYGSGMAPP----SQGPPG 145
VASS P + S S+ S ++T L S + ++ PP S GP
Sbjct: 763 -VASSPKECPTEDSGASATAS--SKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDT 819
Query: 146 PLSATSLQTPPRPPQPSIL------------QPGSQVLPPPPTTLNGPGASPLPLPMYRP 193
P+ +L +P P + S L P + P PP+ P +P + P
Sbjct: 820 PIG--NLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAP--TPSAVTPLSP 875
Query: 194 DGLSGPPPPNAQYQPPPLPGQTLGAGYP-PQQA------NSGPQMAGAQLSYPGGFPGGP 246
G++ PP LP G P P+QA +S P+ A A + P G P P
Sbjct: 876 KGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPA-PKGIPASP 934
Query: 247 AQMAGPPQPQKKLDPDSIPSPIQVIENDRASRGGQVYATNTRGQIPPLVTTDCMIQDQGN 306
+ P P + PSP +GG + PP T
Sbjct: 935 SPKGAPTPPAA-----TPPSP----------KGGPATPSPKWAPTPPAATPPSPKGGPAT 979
Query: 307 ASPRFIRCTTYCFPCTSDMAKQAQIPLAAVIKPFATIPS 345
SP+ P + P A P T PS
Sbjct: 980 PSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPS 1018
Score = 36.2 bits (82), Expect = 0.16
Identities = 63/280 (22%), Positives = 86/280 (30%), Gaps = 46/280 (16%)
Query: 17 PGIGLSPPHYGHYGDPSHTASPTGMMKPAGPLGATATRGMLPPGPPP------PGPHQFG 70
P L PP A PT PA P A+ PP P P P +
Sbjct: 1544 PKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASS---PPAVTPSTYKGAPSPKELL 1600
Query: 71 QNGAHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGSQLSAMQIN 130
A T P+ P PP V + P P+ + + P T S + A
Sbjct: 1601 IPPA-VTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTC 1659
Query: 131 SYGSGMAPPSQGPP---GPLSATSLQTPPRP-------------PQPSILQPGSQVLPPP 174
G+ + S+G P GP + + P P PQ S + P
Sbjct: 1660 KMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPD 1719
Query: 175 PTTLNG-----PGASPLPLPMYRPDGLSGPPPPNAQYQPPPLPGQTLGAGYPPQQANSGP 229
P+ NG +P PL + D +A + P G PP+ S P
Sbjct: 1720 PSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPK-------GPLAPPESKASTP 1772
Query: 230 QMAGA--------QLSYPGGFPGGPAQMAGPPQPQKKLDP 261
A A + + P P + P P L P
Sbjct: 1773 LTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPP 1812
Score = 35.0 bits (79), Expect = 0.37
Identities = 77/341 (22%), Positives = 114/341 (33%), Gaps = 47/341 (13%)
Query: 9 TPPYSQPQPGIGLSPPHYGHYGDPSHTASPTGMMKPAGPLGATATRGMLPPGPPPPGPHQ 68
TP S P + L+P H S P + P A + + P P +
Sbjct: 130 TPSSSAPLALVALAP----HSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPK 185
Query: 69 FGQNGAHATGHP-PQRFPGPPPVNNVASSHAPY-QPSAQSSYPGPISTSSVTQLGSQLSA 126
N + P P+ P PP + + H S QS T+ T L
Sbjct: 186 TNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQ 245
Query: 127 MQINSYGSGMAPPS-------QGPPGPLSATSLQTPPRPPQPSILQPGSQVLPPPPTTLN 179
++ + S + P +GP P +A SL T P S + PP
Sbjct: 246 VKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISL 305
Query: 180 GPGASPLPLPMYRPDGLSGPPPPNAQYQPP----PLPGQTLGAGYPPQQANSGPQMAGAQ 235
G +PL + L G P+A P + + GA YP Q++ P
Sbjct: 306 GSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPP------ 359
Query: 236 LSYPGGFPGGPAQMAGPPQPQKKLDPDSIPSPIQVIENDRASRGGQVYATNTRGQIPPLV 295
P PA +A P +D PS I I S G + + P
Sbjct: 360 --LPSRNEVVPATVAAFPVVAPSVDKG--PSTISSI---TCSPSGSLNVATSFSLSP--- 409
Query: 296 TTDCMIQDQGNASPRFIRCTTYCFPCTSDMAKQAQIPLAAV 336
TT +++ NA TY +P AQ+P+++V
Sbjct: 410 TTSLILKSSPNA--------TYHYPLV------AQMPVSSV 436
Score = 32.0 bits (71), Expect = 3.1
Identities = 68/279 (24%), Positives = 91/279 (32%), Gaps = 65/279 (23%)
Query: 9 TPP-YSQPQPGIGLSPPHYGHYGDPSHTASPTGMMK--PAGPLGATATRGMLPPGPPPPG 65
TPP + P P G + P G P+ +K P P T G P
Sbjct: 1615 TPPAVTPPSPEKGPATP--APKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGL 1672
Query: 66 PHQFGQNGAHATGHPPQRFPGP---------PPVNNVASSHAPY--QPSAQSSYPGPIST 114
P + G P P P +++ P PSA++ GP+ST
Sbjct: 1673 PAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLST 1732
Query: 115 ------------SSVTQLGSQLSAMQINSYGSGMAPPSQGPPGPLSAT------------ 150
SS T G S +S +APP PL+A
Sbjct: 1733 VAPAPLLPVQKDSSKTAKGKDAS----HSPKGPLAPPESKASTPLTAAAFEKVLPKPESA 1788
Query: 151 SLQTPPRPP-----QPS---ILQPGSQVLPPPPTTLNGPGASPLP-------LPMYRPDG 195
S+ P PP PS L P Q LP P + + PL LP+ P+
Sbjct: 1789 SVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEP 1848
Query: 196 LSGPPPPNAQY--QPPP----LPGQTLGAGYPPQQANSG 228
+SG P + P P +P T A P + N G
Sbjct: 1849 ISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKG 1887
>gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 73.9 bits (180), Expect = 7e-13
Identities = 79/288 (27%), Positives = 101/288 (35%), Gaps = 61/288 (21%)
Query: 23 PPHYGHYGDPSHTASPTGMMKPAGPLGATATRGMLPPGPPPPGPHQFGQNGAH------- 75
P Y + D S++ S + + L R ++ P PPP P G A
Sbjct: 239 PQTYVDHMDGSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCIS 298
Query: 76 -ATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGSQLSAMQINSYGS 134
ATG R P P +P P P +STSS + + +
Sbjct: 299 SATGLIENR-PQSPATGRTPVFVSPTPPPPPPPLPSALSTSS------------LRASMT 345
Query: 135 GMAPPSQGPPGPLSATSLQTPPRPPQPSILQPGSQVLPPPPTTLNGPGASPL-------- 186
PP PP P AT+LQ P PP P+ LQ VL P P + P P
Sbjct: 346 STPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAP 405
Query: 187 --------PLPMYRPDGLSGPPPPNAQYQPPPLPGQTLGAGYPPQQANSGPQMAGAQLSY 238
PLP GL PPP PPPLP PP S P A
Sbjct: 406 VCETVPVHPLPQGEVQGLPPPPP------PPPLP--------PPGIRPSSPVTVTALAHP 451
Query: 239 PGGFPGGPAQMAG------PPQPQKKL----DPDSIPSPIQVIENDRA 276
P G P+ G PP P ++ +P PS + VI + R+
Sbjct: 452 PSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPSTLPVISDARS 499
>gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 73.9 bits (180), Expect = 7e-13
Identities = 79/288 (27%), Positives = 101/288 (35%), Gaps = 61/288 (21%)
Query: 23 PPHYGHYGDPSHTASPTGMMKPAGPLGATATRGMLPPGPPPPGPHQFGQNGAH------- 75
P Y + D S++ S + + L R ++ P PPP P G A
Sbjct: 239 PQTYVDHMDGSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCIS 298
Query: 76 -ATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGSQLSAMQINSYGS 134
ATG R P P +P P P +STSS + + +
Sbjct: 299 SATGLIENR-PQSPATGRTPVFVSPTPPPPPPPLPSALSTSS------------LRASMT 345
Query: 135 GMAPPSQGPPGPLSATSLQTPPRPPQPSILQPGSQVLPPPPTTLNGPGASPL-------- 186
PP PP P AT+LQ P PP P+ LQ VL P P + P P
Sbjct: 346 STPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAP 405
Query: 187 --------PLPMYRPDGLSGPPPPNAQYQPPPLPGQTLGAGYPPQQANSGPQMAGAQLSY 238
PLP GL PPP PPPLP PP S P A
Sbjct: 406 VCETVPVHPLPQGEVQGLPPPPP------PPPLP--------PPGIRPSSPVTVTALAHP 451
Query: 239 PGGFPGGPAQMAG------PPQPQKKL----DPDSIPSPIQVIENDRA 276
P G P+ G PP P ++ +P PS + VI + R+
Sbjct: 452 PSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPSTLPVISDARS 499
>gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 73.9 bits (180), Expect = 7e-13
Identities = 79/288 (27%), Positives = 101/288 (35%), Gaps = 61/288 (21%)
Query: 23 PPHYGHYGDPSHTASPTGMMKPAGPLGATATRGMLPPGPPPPGPHQFGQNGAH------- 75
P Y + D S++ S + + L R ++ P PPP P G A
Sbjct: 239 PQTYVDHMDGSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCIS 298
Query: 76 -ATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGSQLSAMQINSYGS 134
ATG R P P +P P P +STSS + + +
Sbjct: 299 SATGLIENR-PQSPATGRTPVFVSPTPPPPPPPLPSALSTSS------------LRASMT 345
Query: 135 GMAPPSQGPPGPLSATSLQTPPRPPQPSILQPGSQVLPPPPTTLNGPGASPL-------- 186
PP PP P AT+LQ P PP P+ LQ VL P P + P P
Sbjct: 346 STPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAP 405
Query: 187 --------PLPMYRPDGLSGPPPPNAQYQPPPLPGQTLGAGYPPQQANSGPQMAGAQLSY 238
PLP GL PPP PPPLP PP S P A
Sbjct: 406 VCETVPVHPLPQGEVQGLPPPPP------PPPLP--------PPGIRPSSPVTVTALAHP 451
Query: 239 PGGFPGGPAQMAG------PPQPQKKL----DPDSIPSPIQVIENDRA 276
P G P+ G PP P ++ +P PS + VI + R+
Sbjct: 452 PSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPSTLPVISDARS 499
>gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 73.9 bits (180), Expect = 7e-13
Identities = 79/288 (27%), Positives = 101/288 (35%), Gaps = 61/288 (21%)
Query: 23 PPHYGHYGDPSHTASPTGMMKPAGPLGATATRGMLPPGPPPPGPHQFGQNGAH------- 75
P Y + D S++ S + + L R ++ P PPP P G A
Sbjct: 239 PQTYVDHMDGSYSLSALPFSQMSELLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCIS 298
Query: 76 -ATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGSQLSAMQINSYGS 134
ATG R P P +P P P +STSS + + +
Sbjct: 299 SATGLIENR-PQSPATGRTPVFVSPTPPPPPPPLPSALSTSS------------LRASMT 345
Query: 135 GMAPPSQGPPGPLSATSLQTPPRPPQPSILQPGSQVLPPPPTTLNGPGASPL-------- 186
PP PP P AT+LQ P PP P+ LQ VL P P + P P
Sbjct: 346 STPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAP 405
Query: 187 --------PLPMYRPDGLSGPPPPNAQYQPPPLPGQTLGAGYPPQQANSGPQMAGAQLSY 238
PLP GL PPP PPPLP PP S P A
Sbjct: 406 VCETVPVHPLPQGEVQGLPPPPP------PPPLP--------PPGIRPSSPVTVTALAHP 451
Query: 239 PGGFPGGPAQMAG------PPQPQKKL----DPDSIPSPIQVIENDRA 276
P G P+ G PP P ++ +P PS + VI + R+
Sbjct: 452 PSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPSTLPVISDARS 499
>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
sapiens]
Length = 1691
Score = 73.9 bits (180), Expect = 7e-13
Identities = 83/282 (29%), Positives = 99/282 (35%), Gaps = 50/282 (17%)
Query: 11 PYSQPQPGIGLSPPHYGHYGDPSHTASPTGMMKPAGPLGATATRGML----PPGPPP-PG 65
P S+ +PGI P G G P P G GP GA T G + PPGPP PG
Sbjct: 695 PGSKGEPGI----PGIGLPGPPG----PKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPG 746
Query: 66 PHQFGQNGAHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGSQLS 125
P G P PGPP + P +PGP T L
Sbjct: 747 PK----------GEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPG 796
Query: 126 AMQINSYGSGMAPPSQGPPGPLSATSLQTPPRPP--QPSILQPGSQVLP-----PPPTTL 178
G P GPPG L +Q PP PP I QPG +P P P L
Sbjct: 797 PK--GDVGPNGQPGPMGPPG-LPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGL 853
Query: 179 NGPGASPLPLPMYRPDGLSGPPPPNAQYQPPPLPGQTLGAGYP---PQQANSGPQMAGAQ 235
+ PG P G+ G P P P LPG+ +G+P + GP
Sbjct: 854 DVPG----PPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGP 909
Query: 236 LSYPG--GFPG--------GPAQMAGPPQPQKKLDPDSIPSP 267
L PG G PG G + GP + +P P
Sbjct: 910 LGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGP 951
Score = 65.5 bits (158), Expect = 3e-10
Identities = 81/295 (27%), Positives = 91/295 (30%), Gaps = 88/295 (29%)
Query: 32 PSHTASPTGMMKPAGPLGATATRGMLPPGPPP-PGPHQFGQNGAHA-------TGHPPQR 83
P P G P GP G PPGPP PGP GQ G H G P
Sbjct: 797 PKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGP--IGQPGLHGIPGEKGDPGPPGLD 854
Query: 84 FPGPPPVN---NVASSHAPYQPSAQSSYPGPISTSSVTQLGSQLSAMQINSYGSGMAPPS 140
PGPP + + P P PG S ++ M PP
Sbjct: 855 VPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGM---------MGPP- 904
Query: 141 QGPPGPL---------------------------------SATSLQTPPRPPQPSIL--- 164
GPPGPL L PP P P++L
Sbjct: 905 -GPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSK 963
Query: 165 -QPGSQVLPPPPTTLNGPGASPLPLPMYRP-----DGLSGPPPPNAQYQPPPLPGQ---- 214
+ G LP P G LP +P GL GPP P P LPGQ
Sbjct: 964 GEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGN---PGLPGQPGLI 1020
Query: 215 -------TLG-AGYPPQQANSGPQMAGAQLSYPGGFPGGPAQMAGPPQPQKKLDP 261
T+G G+P Q GP P G PG P P Q K DP
Sbjct: 1021 GPPGLKGTIGDMGFPGPQGVEGP-------PGPSGVPGQPGSPGLPGQKGDKGDP 1068
Score = 60.8 bits (146), Expect = 6e-09
Identities = 80/270 (29%), Positives = 93/270 (34%), Gaps = 34/270 (12%)
Query: 17 PGIGLSPPHYGHYGDPSHTASP--TGMMKPAGPLGATATRGMLPPGP-----PPPGPHQF 69
PG +P G GDP P G G G T G PPGP PP P
Sbjct: 1088 PGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPG--PPGPKGISGPPGNPGLP 1145
Query: 70 GQNG-AHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGSQLSAMQ 128
G+ G GHP Q PGPP P+ Q PG + G + Q
Sbjct: 1146 GEPGPVGGGGHPGQ--PGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQ 1203
Query: 129 INSYGSGMAPPSQGPPGPLSATS------LQTPPRP---PQPSILQPGSQVLPPPPTTLN 179
G P + G PGP +Q PP P P P++ P P P
Sbjct: 1204 KGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRP 1263
Query: 180 GP-GASPLPLPMYRP-----DGLSGPPPPNAQYQPPPLPGQTLGAGYPPQQANSGPQMAG 233
GP G LP P P G+ G Q P LPG G P Q N G
Sbjct: 1264 GPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLN 1323
Query: 234 AQLSYPG-----GFPG--GPAQMAGPPQPQ 256
PG GFPG GP+ + G P+
Sbjct: 1324 GMKGDPGLPGVPGFPGMKGPSGVPGSAGPE 1353
Score = 58.5 bits (140), Expect = 3e-08
Identities = 75/267 (28%), Positives = 90/267 (33%), Gaps = 80/267 (29%)
Query: 15 PQPGIGLSPPHYGHYGDPSHTASP-----TGMMKPAGPLGATATRGMLPPGPPPPGPHQF 69
P+PG G++ G+ G P G+ P G G M PPGPP P +
Sbjct: 347 PRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPG-FPGER 405
Query: 70 GQNGAHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGSQLSAMQI 129
GQ G G P PGPP ++ PG
Sbjct: 406 GQKGDE--GPPGISIPGPPGLDG---------------QPG------------------- 429
Query: 130 NSYGSGMAPPSQGPPGPLSATSLQTPPRPPQPSILQPGSQVLPPPPTTLNGPGASPLPLP 189
AP GPPGP P PP I +PG PP PG L
Sbjct: 430 -------APGLPGPPGPAG------PHIPPSDEICEPG------PPGPPGSPGDKGLQGE 470
Query: 190 M-YRPD-----------GLSGPPPPNAQYQPPPLPGQTLGAGYPPQQANSGPQMAGAQLS 237
+ D G+SGPP Q P LPG G+P Q+ G AGA +
Sbjct: 471 QGVKGDKGDTCFNCIGTGISGPP---GQPGLPGLPGPPGSLGFPGQKGEKG--QAGA--T 523
Query: 238 YPGGFPGGPAQMAGPPQPQKKLDPDSI 264
P G PG P P P K +P I
Sbjct: 524 GPKGLPGIPGAPGAPGFPGSKGEPGDI 550
Score = 55.1 bits (131), Expect = 3e-07
Identities = 84/274 (30%), Positives = 99/274 (36%), Gaps = 49/274 (17%)
Query: 27 GHYGDPSHTASPTGMMKPAGPLGATATRGMLPPGPPPP-GPHQFGQNGAHATGHPPQRFP 85
G GD P G+ P G G+ G+ PGPP P P+ G G G P P
Sbjct: 920 GLKGDDGLQGQP-GLPGPTGEKGSKGEPGL--PGPPGPMDPNLLGSKGEK--GEPG--LP 972
Query: 86 GPPPVNNVASSHA----PYQP--SAQSSYPGPISTSSVTQLGSQLSAMQINSYGSGMAPP 139
G P V+ P QP S Q PGP L Q + PP
Sbjct: 973 GIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLI---------GPP 1023
Query: 140 S-QGPPGPLSATSLQTPPRPPQPSIL--QPGSQVLPPPPTTLNGPGASPLPLP-MYRPDG 195
+G G + Q PP PS + QPGS LP PG S + LP + P G
Sbjct: 1024 GLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKG 1083
Query: 196 LSGPP--PPNAQYQ----PPPLPGQ--TLGA-------GYPPQQANSGPQMAGAQLSYPG 240
G P P N + P LPG T GA G+P GP+ PG
Sbjct: 1084 EPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPG 1143
Query: 241 --GFPG-----GPAQMAGPPQPQKKLDPDSIPSP 267
G PG G GPP + K D IP P
Sbjct: 1144 LPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGP 1177
Score = 53.5 bits (127), Expect = 1e-06
Identities = 71/255 (27%), Positives = 84/255 (32%), Gaps = 42/255 (16%)
Query: 8 ATPPYSQPQ-PGIGLSPPHYGHYGDPSHTASPTGMMKPAGPLGATATRGMLPPGPPPPGP 66
AT P P PG +P G G+P + GM G LG+ G LP P PG
Sbjct: 522 ATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPG-LPGLPGTPG- 579
Query: 67 HQFGQNGAHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGSQLSA 126
Q+G P G P P PG I
Sbjct: 580 ----QDGLPGLPGPK----GEPGGITFKGERGPPGNPGLPGLPGNIGP------------ 619
Query: 127 MQINSYGSGMAPPSQGPPGPLSATSLQ-TPPRPPQPSILQPGSQVLPPPPTTLNGPGASP 185
M PP GPPGP+ +Q P QP I P P T+ PG
Sbjct: 620 ---------MGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGD----PGQTITQPGKPG 666
Query: 186 LPLPMYRPDGLSGPPPPNAQYQP--PPLPGQTLGAGYPPQQANSGPQMAG-AQLSYPGGF 242
LP R + P P QP P +PG G P P G + P G
Sbjct: 667 LPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGA 726
Query: 243 PGGPAQ--MAGPPQP 255
PG P + + GPP P
Sbjct: 727 PGTPGRIGLEGPPGP 741
Score = 53.1 bits (126), Expect = 1e-06
Identities = 68/266 (25%), Positives = 83/266 (31%), Gaps = 38/266 (14%)
Query: 10 PPYSQPQPGIGLSPPHYGHYGDPSHTASP--TGMMKPAGPLGATATRGMLPPGPPPPGPH 67
PP PG P GH G P P G G G+ G+ P PP P
Sbjct: 94 PPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPG 153
Query: 68 QFGQNGAHATGHPP-----QRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGS 122
G+ G+ P +PGPP + + + PGPI L
Sbjct: 154 MKGEPGSIIMSSLPGPKGNPGYPGPPGIQGL---------PGPTGIPGPIGPPGPPGLMG 204
Query: 123 QLSAMQINSYGSGMAPPSQGPPGPLSATSLQTPPRPPQPSILQPGSQVLPPPPTTLNGPG 182
+ M QGP G LQ PP PP Q Q P G
Sbjct: 205 PPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPG----QISEQKRPIDVEFQKGDQ 260
Query: 183 ASPLPLPMYRPDGLSGPPPPNAQYQPPPLPGQTLGAGYPPQQANSGPQMAGAQLSYPG-- 240
P P G+ GPP P P G+ G P ++ G Q PG
Sbjct: 261 GLPGDRGPPGPPGIRGPPGP-----PGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLP 315
Query: 241 ---GFPGGPAQ--------MAGPPQP 255
G+PG P + GPP P
Sbjct: 316 GDPGYPGEPGRDGEKGQKGDTGPPGP 341
Score = 51.2 bits (121), Expect = 5e-06
Identities = 77/270 (28%), Positives = 96/270 (35%), Gaps = 47/270 (17%)
Query: 3 QQGYVATPPYSQP-QPGIGLSPPHYGHYGDPSHTASPTGMMKPAGPLGATATRGML-PPG 60
Q+G P + P PG+ G G P +P G+ P G G G+ PPG
Sbjct: 1180 QKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNP-GLPGPKGEPGFHGFPGVQGPPG 1238
Query: 61 PP-PPGPHQFGQNGAHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQ 119
PP PGP G G PP R PGP + P PG +
Sbjct: 1239 PPGSPGPALEGPKGNPGPQGPPGR-PGPTGFQGLPGPEGP---------PGLPGNGGIK- 1287
Query: 120 LGSQLSAMQINSYGSGMAPPSQGPPGPLSATSLQTPPRPPQPSILQ--PGSQVLPPPPTT 177
G + + Q G QGPPG LQ P P + ++ PG +P P
Sbjct: 1288 -GEKGNPGQPGLPGLPGLKGDQGPPG------LQGNPGRPGLNGMKGDPGLPGVPGFPG- 1339
Query: 178 LNGPGASPLPLPMYRPDGLSGPPPPNAQYQPPPLPGQTLGAGYPPQQANSGPQMAGAQLS 237
+ GP P GL GPP P P LPG SG + +
Sbjct: 1340 MKGPSGVPGSAGPEGEPGLIGPPGP------PGLPGP------------SGQSIIIKGDA 1381
Query: 238 YPGGFPGGPAQMAGPPQPQKKLDPDSIPSP 267
P G PG P + G P PQ P +P P
Sbjct: 1382 GPPGIPGQPG-LKGLPGPQ---GPQGLPGP 1407
Score = 49.7 bits (117), Expect = 1e-05
Identities = 71/255 (27%), Positives = 88/255 (34%), Gaps = 52/255 (20%)
Query: 4 QGYVATP-----PYSQPQPGIGLSPPHYGHYGDPSHTASPTGMMKPAGPLGATATRGMLP 58
+GY P P QPG+ PP G G+P P G++ P G G G
Sbjct: 981 KGYQGLPGDPGQPGLSGQPGLP-GPP--GPKGNPGLPGQP-GLIGPPGLKGTIGDMGF-- 1034
Query: 59 PGPP----PPGPHQF-GQNGAHATGHPPQRFP-GPPPVNNVASSHAPYQPSAQSSYPGPI 112
PGP PPGP GQ G+ G P Q+ G P ++++ P P + PG
Sbjct: 1035 PGPQGVEGPPGPSGVPGQPGS--PGLPGQKGDKGDPGISSIGLPGLP-GPKGEPGLPGYP 1091
Query: 113 STSSVTQLGSQLSAMQINSYGSGMAPPSQGPPGPLSATSLQTPPRPPQPSILQPGSQVLP 172
+ S G P G PG L P P P
Sbjct: 1092 GNPGIK-----------GSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGP----------- 1129
Query: 173 PPPTTLNGPGASPLPLPMYRPDGLSGPPPPNAQYQPPPLPGQTLGAGYPPQQANSGPQMA 232
P P ++GP +P GL G P P P PG G P Q GP
Sbjct: 1130 PGPKGISGPPGNP---------GLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQ 1180
Query: 233 GAQLSYPG-GFPGGP 246
+ PG G PG P
Sbjct: 1181 KGEPGQPGFGNPGPP 1195
Score = 47.4 bits (111), Expect = 7e-05
Identities = 44/144 (30%), Positives = 51/144 (35%), Gaps = 26/144 (18%)
Query: 138 PPSQGPPGPLSATSLQTPPRPPQPSILQ--PGSQVLPPPPTTLNGPGASPLPLPMYRP-- 193
P +GPPGP P PP P ++ PG P P PG P P P
Sbjct: 65 PGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGC 124
Query: 194 ---------------DGLSGPPPPNAQYQPPPLPGQTLGAGYPPQQANSG-PQMAGAQ-L 236
GL GPP P PG + + P + N G P G Q L
Sbjct: 125 NGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGL 184
Query: 237 SYPGGFPG-----GPAQMAGPPQP 255
P G PG GP + GPP P
Sbjct: 185 PGPTGIPGPIGPPGPPGLMGPPGP 208
Score = 47.4 bits (111), Expect = 7e-05
Identities = 50/175 (28%), Positives = 65/175 (37%), Gaps = 14/175 (8%)
Query: 10 PPYSQPQPGIGLSPPHYGHYGDPSHTASP--TGMMKPAGPLGATATRG----MLPPGPPP 63
PP Q PG P G GDP P GM P+G G+ G + PPGPP
Sbjct: 1310 PPGLQGNPG---RPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPG 1366
Query: 64 -PGPHQFGQNGAHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGS 122
PGP GQ+ P PG P + + P + PG + + G
Sbjct: 1367 LPGPS--GQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLP--GF 1422
Query: 123 QLSAMQINSYGSGMAPPSQGPPGPLSATSLQTPPRPPQPSILQPGSQVLPPPPTT 177
+ + G P ++G GP LQ PP PP S + G + TT
Sbjct: 1423 DGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTT 1477
Score = 45.8 bits (107), Expect = 2e-04
Identities = 65/247 (26%), Positives = 84/247 (34%), Gaps = 44/247 (17%)
Query: 23 PPHYGHYGDPSHTASPTGMMKPAGPLGATATRGMLPPGPP----PPGPHQFGQNGAHATG 78
PP G G S P + G G RG PPGPP PPGP + G
Sbjct: 237 PP--GPPGQISEQKRPIDVEFQKGDQGLPGDRG--PPGPPGIRGPPGPPGGEKGEKGEQG 292
Query: 79 HPPQR----------------FPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGS 122
P +R PG P + PGP + + G+
Sbjct: 293 EPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLV-IPRPGT 351
Query: 123 QLSAMQINSYGSGMAPPSQGPPGPLSATSLQTPPRPPQPSILQPGSQVLPPPPTTLNGPG 182
++ I G+ P G G +Q PP P P PG+ V+ PP GP
Sbjct: 352 GIT---IGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGP----PGAAVMGPP-----GPP 399
Query: 183 ASPLPLPMYRPDGLSGPPPPNAQYQPPPLPGQTLGAGYPPQQANSGPQMAGA-QLSYPG- 240
P +G G P PP L GQ G P +GP + + ++ PG
Sbjct: 400 GFPGERGQKGDEGPPGISIPG----PPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGP 455
Query: 241 -GFPGGP 246
G PG P
Sbjct: 456 PGPPGSP 462
Score = 44.7 bits (104), Expect = 5e-04
Identities = 78/276 (28%), Positives = 90/276 (32%), Gaps = 55/276 (19%)
Query: 7 VATPPYSQPQPGIGLSPP--HYGHYGDPSHTASPTGMMK---PAGPLGATATRGMLPPGP 61
V PP PG L P + G G P PTG P GP G G+
Sbjct: 1233 VQGPPGPPGSPGPALEGPKGNPGPQGPPGRPG-PTGFQGLPGPEGPPGLPGNGGIKGEKG 1291
Query: 62 PPPGPHQFGQNGAHATGHPP--QRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQ 119
P P G G PP Q PG P +N + P P +PG S V
Sbjct: 1292 NPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGD--PGLPGVPG-FPGMKGPSGVP- 1347
Query: 120 LGSQLSAMQINSYGSGMAPPSQGPPGP--LSATSLQT---------PPRPPQPSIL---- 164
S G P GPPGP L S Q+ P P QP +
Sbjct: 1348 ----------GSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPG 1397
Query: 165 QPGSQVLPPPPTTLNGPGASPLP-------------LP-MYRPDGLSGPPPPNAQYQPPP 210
G Q LP P PG + LP LP GL GPP P+ PP
Sbjct: 1398 PQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPG 1457
Query: 211 LPG-QTLGAGY---PPQQANSGPQMAGAQLSYPGGF 242
PG ++ G+ Q PQ L GF
Sbjct: 1458 PPGTSSVAHGFLITRHSQTTDAPQCPQGTLQVYEGF 1493
>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
sapiens]
Length = 1685
Score = 73.9 bits (180), Expect = 7e-13
Identities = 83/282 (29%), Positives = 99/282 (35%), Gaps = 50/282 (17%)
Query: 11 PYSQPQPGIGLSPPHYGHYGDPSHTASPTGMMKPAGPLGATATRGML----PPGPPP-PG 65
P S+ +PGI P G G P P G GP GA T G + PPGPP PG
Sbjct: 695 PGSKGEPGI----PGIGLPGPPG----PKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPG 746
Query: 66 PHQFGQNGAHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGSQLS 125
P G P PGPP + P +PGP T L
Sbjct: 747 PK----------GEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPG 796
Query: 126 AMQINSYGSGMAPPSQGPPGPLSATSLQTPPRPP--QPSILQPGSQVLP-----PPPTTL 178
G P GPPG L +Q PP PP I QPG +P P P L
Sbjct: 797 PK--GDVGPNGQPGPMGPPG-LPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGL 853
Query: 179 NGPGASPLPLPMYRPDGLSGPPPPNAQYQPPPLPGQTLGAGYP---PQQANSGPQMAGAQ 235
+ PG P G+ G P P P LPG+ +G+P + GP
Sbjct: 854 DVPG----PPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGP 909
Query: 236 LSYPG--GFPG--------GPAQMAGPPQPQKKLDPDSIPSP 267
L PG G PG G + GP + +P P
Sbjct: 910 LGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGP 951
Score = 65.5 bits (158), Expect = 3e-10
Identities = 81/295 (27%), Positives = 91/295 (30%), Gaps = 88/295 (29%)
Query: 32 PSHTASPTGMMKPAGPLGATATRGMLPPGPPP-PGPHQFGQNGAHA-------TGHPPQR 83
P P G P GP G PPGPP PGP GQ G H G P
Sbjct: 797 PKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGP--IGQPGLHGIPGEKGDPGPPGLD 854
Query: 84 FPGPPPVN---NVASSHAPYQPSAQSSYPGPISTSSVTQLGSQLSAMQINSYGSGMAPPS 140
PGPP + + P P PG S ++ M PP
Sbjct: 855 VPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGM---------MGPP- 904
Query: 141 QGPPGPL---------------------------------SATSLQTPPRPPQPSIL--- 164
GPPGPL L PP P P++L
Sbjct: 905 -GPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSK 963
Query: 165 -QPGSQVLPPPPTTLNGPGASPLPLPMYRP-----DGLSGPPPPNAQYQPPPLPGQ---- 214
+ G LP P G LP +P GL GPP P P LPGQ
Sbjct: 964 GEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGN---PGLPGQPGLI 1020
Query: 215 -------TLG-AGYPPQQANSGPQMAGAQLSYPGGFPGGPAQMAGPPQPQKKLDP 261
T+G G+P Q GP P G PG P P Q K DP
Sbjct: 1021 GPPGLKGTIGDMGFPGPQGVEGP-------PGPSGVPGQPGSPGLPGQKGDKGDP 1068
Score = 59.7 bits (143), Expect = 1e-08
Identities = 79/268 (29%), Positives = 91/268 (33%), Gaps = 36/268 (13%)
Query: 17 PGIGLSPPHYGHYGDPSHTASP--TGMMKPAGPLGATATRGMLPPGP-----PPPGPHQF 69
PG +P G GDP P G G G T G PPGP PP P
Sbjct: 1088 PGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPG--PPGPKGISGPPGNPGLP 1145
Query: 70 GQNG-AHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGSQLSAMQ 128
G+ G GHP Q PGPP P+ Q PG + G + Q
Sbjct: 1146 GEPGPVGGGGHPGQ--PGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQ 1203
Query: 129 INSYGSGMAPPSQGPPGPLSATS------LQTPPRPPQPSILQPGSQVLPPP--PTTLNG 180
G P + G PGP +Q PP PP PG + P P
Sbjct: 1204 KGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPG----SPGPALEGPKGNPGPQGP 1259
Query: 181 PGASPLPLPMYRP-----DGLSGPPPPNAQYQPPPLPGQTLGAGYPPQQANSGPQMAGAQ 235
PG LP P P G+ G Q P LPG G P Q N G
Sbjct: 1260 PGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGM 1319
Query: 236 LSYPG-----GFPG--GPAQMAGPPQPQ 256
PG GFPG GP+ + G P+
Sbjct: 1320 KGDPGLPGVPGFPGMKGPSGVPGSAGPE 1347
Score = 58.5 bits (140), Expect = 3e-08
Identities = 75/267 (28%), Positives = 90/267 (33%), Gaps = 80/267 (29%)
Query: 15 PQPGIGLSPPHYGHYGDPSHTASP-----TGMMKPAGPLGATATRGMLPPGPPPPGPHQF 69
P+PG G++ G+ G P G+ P G G M PPGPP P +
Sbjct: 347 PRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPG-FPGER 405
Query: 70 GQNGAHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGSQLSAMQI 129
GQ G G P PGPP ++ PG
Sbjct: 406 GQKGDE--GPPGISIPGPPGLDG---------------QPG------------------- 429
Query: 130 NSYGSGMAPPSQGPPGPLSATSLQTPPRPPQPSILQPGSQVLPPPPTTLNGPGASPLPLP 189
AP GPPGP P PP I +PG PP PG L
Sbjct: 430 -------APGLPGPPGPAG------PHIPPSDEICEPG------PPGPPGSPGDKGLQGE 470
Query: 190 M-YRPD-----------GLSGPPPPNAQYQPPPLPGQTLGAGYPPQQANSGPQMAGAQLS 237
+ D G+SGPP Q P LPG G+P Q+ G AGA +
Sbjct: 471 QGVKGDKGDTCFNCIGTGISGPP---GQPGLPGLPGPPGSLGFPGQKGEKG--QAGA--T 523
Query: 238 YPGGFPGGPAQMAGPPQPQKKLDPDSI 264
P G PG P P P K +P I
Sbjct: 524 GPKGLPGIPGAPGAPGFPGSKGEPGDI 550
Score = 55.1 bits (131), Expect = 3e-07
Identities = 84/274 (30%), Positives = 99/274 (36%), Gaps = 49/274 (17%)
Query: 27 GHYGDPSHTASPTGMMKPAGPLGATATRGMLPPGPPPP-GPHQFGQNGAHATGHPPQRFP 85
G GD P G+ P G G+ G+ PGPP P P+ G G G P P
Sbjct: 920 GLKGDDGLQGQP-GLPGPTGEKGSKGEPGL--PGPPGPMDPNLLGSKGEK--GEPG--LP 972
Query: 86 GPPPVNNVASSHA----PYQP--SAQSSYPGPISTSSVTQLGSQLSAMQINSYGSGMAPP 139
G P V+ P QP S Q PGP L Q + PP
Sbjct: 973 GIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLI---------GPP 1023
Query: 140 S-QGPPGPLSATSLQTPPRPPQPSIL--QPGSQVLPPPPTTLNGPGASPLPLP-MYRPDG 195
+G G + Q PP PS + QPGS LP PG S + LP + P G
Sbjct: 1024 GLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKG 1083
Query: 196 LSGPP--PPNAQYQ----PPPLPGQ--TLGA-------GYPPQQANSGPQMAGAQLSYPG 240
G P P N + P LPG T GA G+P GP+ PG
Sbjct: 1084 EPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPG 1143
Query: 241 --GFPG-----GPAQMAGPPQPQKKLDPDSIPSP 267
G PG G GPP + K D IP P
Sbjct: 1144 LPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGP 1177
Score = 53.5 bits (127), Expect = 1e-06
Identities = 71/255 (27%), Positives = 84/255 (32%), Gaps = 42/255 (16%)
Query: 8 ATPPYSQPQ-PGIGLSPPHYGHYGDPSHTASPTGMMKPAGPLGATATRGMLPPGPPPPGP 66
AT P P PG +P G G+P + GM G LG+ G LP P PG
Sbjct: 522 ATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPG-LPGLPGTPG- 579
Query: 67 HQFGQNGAHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGSQLSA 126
Q+G P G P P PG I
Sbjct: 580 ----QDGLPGLPGPK----GEPGGITFKGERGPPGNPGLPGLPGNIGP------------ 619
Query: 127 MQINSYGSGMAPPSQGPPGPLSATSLQ-TPPRPPQPSILQPGSQVLPPPPTTLNGPGASP 185
M PP GPPGP+ +Q P QP I P P T+ PG
Sbjct: 620 ---------MGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGD----PGQTITQPGKPG 666
Query: 186 LPLPMYRPDGLSGPPPPNAQYQP--PPLPGQTLGAGYPPQQANSGPQMAG-AQLSYPGGF 242
LP R + P P QP P +PG G P P G + P G
Sbjct: 667 LPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGA 726
Query: 243 PGGPAQ--MAGPPQP 255
PG P + + GPP P
Sbjct: 727 PGTPGRIGLEGPPGP 741
Score = 53.1 bits (126), Expect = 1e-06
Identities = 68/266 (25%), Positives = 83/266 (31%), Gaps = 38/266 (14%)
Query: 10 PPYSQPQPGIGLSPPHYGHYGDPSHTASP--TGMMKPAGPLGATATRGMLPPGPPPPGPH 67
PP PG P GH G P P G G G+ G+ P PP P
Sbjct: 94 PPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPG 153
Query: 68 QFGQNGAHATGHPP-----QRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGS 122
G+ G+ P +PGPP + + + PGPI L
Sbjct: 154 MKGEPGSIIMSSLPGPKGNPGYPGPPGIQGL---------PGPTGIPGPIGPPGPPGLMG 204
Query: 123 QLSAMQINSYGSGMAPPSQGPPGPLSATSLQTPPRPPQPSILQPGSQVLPPPPTTLNGPG 182
+ M QGP G LQ PP PP Q Q P G
Sbjct: 205 PPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPG----QISEQKRPIDVEFQKGDQ 260
Query: 183 ASPLPLPMYRPDGLSGPPPPNAQYQPPPLPGQTLGAGYPPQQANSGPQMAGAQLSYPG-- 240
P P G+ GPP P P G+ G P ++ G Q PG
Sbjct: 261 GLPGDRGPPGPPGIRGPPGP-----PGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLP 315
Query: 241 ---GFPGGPAQ--------MAGPPQP 255
G+PG P + GPP P
Sbjct: 316 GDPGYPGEPGRDGEKGQKGDTGPPGP 341
Score = 49.7 bits (117), Expect = 1e-05
Identities = 71/255 (27%), Positives = 88/255 (34%), Gaps = 52/255 (20%)
Query: 4 QGYVATP-----PYSQPQPGIGLSPPHYGHYGDPSHTASPTGMMKPAGPLGATATRGMLP 58
+GY P P QPG+ PP G G+P P G++ P G G G
Sbjct: 981 KGYQGLPGDPGQPGLSGQPGLP-GPP--GPKGNPGLPGQP-GLIGPPGLKGTIGDMGF-- 1034
Query: 59 PGPP----PPGPHQF-GQNGAHATGHPPQRFP-GPPPVNNVASSHAPYQPSAQSSYPGPI 112
PGP PPGP GQ G+ G P Q+ G P ++++ P P + PG
Sbjct: 1035 PGPQGVEGPPGPSGVPGQPGS--PGLPGQKGDKGDPGISSIGLPGLP-GPKGEPGLPGYP 1091
Query: 113 STSSVTQLGSQLSAMQINSYGSGMAPPSQGPPGPLSATSLQTPPRPPQPSILQPGSQVLP 172
+ S G P G PG L P P P
Sbjct: 1092 GNPGIK-----------GSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGP----------- 1129
Query: 173 PPPTTLNGPGASPLPLPMYRPDGLSGPPPPNAQYQPPPLPGQTLGAGYPPQQANSGPQMA 232
P P ++GP +P GL G P P P PG G P Q GP
Sbjct: 1130 PGPKGISGPPGNP---------GLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQ 1180
Query: 233 GAQLSYPG-GFPGGP 246
+ PG G PG P
Sbjct: 1181 KGEPGQPGFGNPGPP 1195
Score = 47.4 bits (111), Expect = 7e-05
Identities = 44/144 (30%), Positives = 51/144 (35%), Gaps = 26/144 (18%)
Query: 138 PPSQGPPGPLSATSLQTPPRPPQPSILQ--PGSQVLPPPPTTLNGPGASPLPLPMYRP-- 193
P +GPPGP P PP P ++ PG P P PG P P P
Sbjct: 65 PGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGC 124
Query: 194 ---------------DGLSGPPPPNAQYQPPPLPGQTLGAGYPPQQANSG-PQMAGAQ-L 236
GL GPP P PG + + P + N G P G Q L
Sbjct: 125 NGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGL 184
Query: 237 SYPGGFPG-----GPAQMAGPPQP 255
P G PG GP + GPP P
Sbjct: 185 PGPTGIPGPIGPPGPPGLMGPPGP 208
Score = 47.4 bits (111), Expect = 7e-05
Identities = 50/175 (28%), Positives = 65/175 (37%), Gaps = 14/175 (8%)
Query: 10 PPYSQPQPGIGLSPPHYGHYGDPSHTASP--TGMMKPAGPLGATATRG----MLPPGPPP 63
PP Q PG P G GDP P GM P+G G+ G + PPGPP
Sbjct: 1304 PPGLQGNPG---RPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPG 1360
Query: 64 -PGPHQFGQNGAHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGS 122
PGP GQ+ P PG P + + P + PG + + G
Sbjct: 1361 LPGPS--GQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLP--GF 1416
Query: 123 QLSAMQINSYGSGMAPPSQGPPGPLSATSLQTPPRPPQPSILQPGSQVLPPPPTT 177
+ + G P ++G GP LQ PP PP S + G + TT
Sbjct: 1417 DGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTT 1471
Score = 45.8 bits (107), Expect = 2e-04
Identities = 65/247 (26%), Positives = 84/247 (34%), Gaps = 44/247 (17%)
Query: 23 PPHYGHYGDPSHTASPTGMMKPAGPLGATATRGMLPPGPP----PPGPHQFGQNGAHATG 78
PP G G S P + G G RG PPGPP PPGP + G
Sbjct: 237 PP--GPPGQISEQKRPIDVEFQKGDQGLPGDRG--PPGPPGIRGPPGPPGGEKGEKGEQG 292
Query: 79 HPPQR----------------FPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGS 122
P +R PG P + PGP + + G+
Sbjct: 293 EPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLV-IPRPGT 351
Query: 123 QLSAMQINSYGSGMAPPSQGPPGPLSATSLQTPPRPPQPSILQPGSQVLPPPPTTLNGPG 182
++ I G+ P G G +Q PP P P PG+ V+ PP GP
Sbjct: 352 GIT---IGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGP----PGAAVMGPP-----GPP 399
Query: 183 ASPLPLPMYRPDGLSGPPPPNAQYQPPPLPGQTLGAGYPPQQANSGPQMAGA-QLSYPG- 240
P +G G P PP L GQ G P +GP + + ++ PG
Sbjct: 400 GFPGERGQKGDEGPPGISIPG----PPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGP 455
Query: 241 -GFPGGP 246
G PG P
Sbjct: 456 PGPPGSP 462
Score = 45.4 bits (106), Expect = 3e-04
Identities = 76/273 (27%), Positives = 89/273 (32%), Gaps = 55/273 (20%)
Query: 7 VATPPYSQPQPGIGLSPPHYGHYGDPSHTASP--TGMMKPAGPLGATATRGMLPPGPPPP 64
V PP PG L P G+P P G+ P GP G G+ P
Sbjct: 1233 VQGPPGPPGSPGPALEGPK----GNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPG 1288
Query: 65 GPHQFGQNGAHATGHPP--QRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGS 122
P G G PP Q PG P +N + P P +PG S V
Sbjct: 1289 QPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGD--PGLPGVPG-FPGMKGPSGVP---- 1341
Query: 123 QLSAMQINSYGSGMAPPSQGPPGP--LSATSLQT---------PPRPPQPSIL----QPG 167
S G P GPPGP L S Q+ P P QP + G
Sbjct: 1342 -------GSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQG 1394
Query: 168 SQVLPPPPTTLNGPGASPLP-------------LP-MYRPDGLSGPPPPNAQYQPPPLPG 213
Q LP P PG + LP LP GL GPP P+ PP PG
Sbjct: 1395 PQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1454
Query: 214 -QTLGAGY---PPQQANSGPQMAGAQLSYPGGF 242
++ G+ Q PQ L GF
Sbjct: 1455 TSSVAHGFLITRHSQTTDAPQCPQGTLQVYEGF 1487
>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
sapiens]
Length = 1688
Score = 73.9 bits (180), Expect = 7e-13
Identities = 83/282 (29%), Positives = 99/282 (35%), Gaps = 50/282 (17%)
Query: 11 PYSQPQPGIGLSPPHYGHYGDPSHTASPTGMMKPAGPLGATATRGML----PPGPPP-PG 65
P S+ +PGI P G G P P G GP GA T G + PPGPP PG
Sbjct: 695 PGSKGEPGI----PGIGLPGPPG----PKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPG 746
Query: 66 PHQFGQNGAHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGSQLS 125
P G P PGPP + P +PGP T L
Sbjct: 747 PK----------GEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPG 796
Query: 126 AMQINSYGSGMAPPSQGPPGPLSATSLQTPPRPP--QPSILQPGSQVLP-----PPPTTL 178
G P GPPG L +Q PP PP I QPG +P P P L
Sbjct: 797 PK--GDVGPNGQPGPMGPPG-LPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGL 853
Query: 179 NGPGASPLPLPMYRPDGLSGPPPPNAQYQPPPLPGQTLGAGYP---PQQANSGPQMAGAQ 235
+ PG P G+ G P P P LPG+ +G+P + GP
Sbjct: 854 DVPG----PPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGP 909
Query: 236 LSYPG--GFPG--------GPAQMAGPPQPQKKLDPDSIPSP 267
L PG G PG G + GP + +P P
Sbjct: 910 LGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGP 951
Score = 65.5 bits (158), Expect = 3e-10
Identities = 81/295 (27%), Positives = 91/295 (30%), Gaps = 88/295 (29%)
Query: 32 PSHTASPTGMMKPAGPLGATATRGMLPPGPPP-PGPHQFGQNGAHA-------TGHPPQR 83
P P G P GP G PPGPP PGP GQ G H G P
Sbjct: 797 PKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGP--IGQPGLHGIPGEKGDPGPPGLD 854
Query: 84 FPGPPPVN---NVASSHAPYQPSAQSSYPGPISTSSVTQLGSQLSAMQINSYGSGMAPPS 140
PGPP + + P P PG S ++ M PP
Sbjct: 855 VPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGM---------MGPP- 904
Query: 141 QGPPGPL---------------------------------SATSLQTPPRPPQPSIL--- 164
GPPGPL L PP P P++L
Sbjct: 905 -GPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSK 963
Query: 165 -QPGSQVLPPPPTTLNGPGASPLPLPMYRP-----DGLSGPPPPNAQYQPPPLPGQ---- 214
+ G LP P G LP +P GL GPP P P LPGQ
Sbjct: 964 GEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGN---PGLPGQPGLI 1020
Query: 215 -------TLG-AGYPPQQANSGPQMAGAQLSYPGGFPGGPAQMAGPPQPQKKLDP 261
T+G G+P Q GP P G PG P P Q K DP
Sbjct: 1021 GPPGLKGTIGDMGFPGPQGVEGP-------PGPSGVPGQPGSPGLPGQKGDKGDP 1068
Score = 58.5 bits (140), Expect = 3e-08
Identities = 75/267 (28%), Positives = 90/267 (33%), Gaps = 80/267 (29%)
Query: 15 PQPGIGLSPPHYGHYGDPSHTASP-----TGMMKPAGPLGATATRGMLPPGPPPPGPHQF 69
P+PG G++ G+ G P G+ P G G M PPGPP P +
Sbjct: 347 PRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPG-FPGER 405
Query: 70 GQNGAHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGSQLSAMQI 129
GQ G G P PGPP ++ PG
Sbjct: 406 GQKGDE--GPPGISIPGPPGLDG---------------QPG------------------- 429
Query: 130 NSYGSGMAPPSQGPPGPLSATSLQTPPRPPQPSILQPGSQVLPPPPTTLNGPGASPLPLP 189
AP GPPGP P PP I +PG PP PG L
Sbjct: 430 -------APGLPGPPGPAG------PHIPPSDEICEPG------PPGPPGSPGDKGLQGE 470
Query: 190 M-YRPD-----------GLSGPPPPNAQYQPPPLPGQTLGAGYPPQQANSGPQMAGAQLS 237
+ D G+SGPP Q P LPG G+P Q+ G AGA +
Sbjct: 471 QGVKGDKGDTCFNCIGTGISGPP---GQPGLPGLPGPPGSLGFPGQKGEKG--QAGA--T 523
Query: 238 YPGGFPGGPAQMAGPPQPQKKLDPDSI 264
P G PG P P P K +P I
Sbjct: 524 GPKGLPGIPGAPGAPGFPGSKGEPGDI 550
Score = 55.1 bits (131), Expect = 3e-07
Identities = 84/274 (30%), Positives = 99/274 (36%), Gaps = 49/274 (17%)
Query: 27 GHYGDPSHTASPTGMMKPAGPLGATATRGMLPPGPPPP-GPHQFGQNGAHATGHPPQRFP 85
G GD P G+ P G G+ G+ PGPP P P+ G G G P P
Sbjct: 920 GLKGDDGLQGQP-GLPGPTGEKGSKGEPGL--PGPPGPMDPNLLGSKGEK--GEPG--LP 972
Query: 86 GPPPVNNVASSHA----PYQP--SAQSSYPGPISTSSVTQLGSQLSAMQINSYGSGMAPP 139
G P V+ P QP S Q PGP L Q + PP
Sbjct: 973 GIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLI---------GPP 1023
Query: 140 S-QGPPGPLSATSLQTPPRPPQPSIL--QPGSQVLPPPPTTLNGPGASPLPLP-MYRPDG 195
+G G + Q PP PS + QPGS LP PG S + LP + P G
Sbjct: 1024 GLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKG 1083
Query: 196 LSGPP--PPNAQYQ----PPPLPGQ--TLGA-------GYPPQQANSGPQMAGAQLSYPG 240
G P P N + P LPG T GA G+P GP+ PG
Sbjct: 1084 EPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPG 1143
Query: 241 --GFPG-----GPAQMAGPPQPQKKLDPDSIPSP 267
G PG G GPP + K D IP P
Sbjct: 1144 LPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGP 1177
Score = 53.5 bits (127), Expect = 1e-06
Identities = 71/255 (27%), Positives = 84/255 (32%), Gaps = 42/255 (16%)
Query: 8 ATPPYSQPQ-PGIGLSPPHYGHYGDPSHTASPTGMMKPAGPLGATATRGMLPPGPPPPGP 66
AT P P PG +P G G+P + GM G LG+ G LP P PG
Sbjct: 522 ATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPG-LPGLPGTPG- 579
Query: 67 HQFGQNGAHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGSQLSA 126
Q+G P G P P PG I
Sbjct: 580 ----QDGLPGLPGPK----GEPGGITFKGERGPPGNPGLPGLPGNIGP------------ 619
Query: 127 MQINSYGSGMAPPSQGPPGPLSATSLQ-TPPRPPQPSILQPGSQVLPPPPTTLNGPGASP 185
M PP GPPGP+ +Q P QP I P P T+ PG
Sbjct: 620 ---------MGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGD----PGQTITQPGKPG 666
Query: 186 LPLPMYRPDGLSGPPPPNAQYQP--PPLPGQTLGAGYPPQQANSGPQMAG-AQLSYPGGF 242
LP R + P P QP P +PG G P P G + P G
Sbjct: 667 LPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGA 726
Query: 243 PGGPAQ--MAGPPQP 255
PG P + + GPP P
Sbjct: 727 PGTPGRIGLEGPPGP 741
Score = 53.1 bits (126), Expect = 1e-06
Identities = 68/266 (25%), Positives = 83/266 (31%), Gaps = 38/266 (14%)
Query: 10 PPYSQPQPGIGLSPPHYGHYGDPSHTASP--TGMMKPAGPLGATATRGMLPPGPPPPGPH 67
PP PG P GH G P P G G G+ G+ P PP P
Sbjct: 94 PPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPG 153
Query: 68 QFGQNGAHATGHPP-----QRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGS 122
G+ G+ P +PGPP + + + PGPI L
Sbjct: 154 MKGEPGSIIMSSLPGPKGNPGYPGPPGIQGL---------PGPTGIPGPIGPPGPPGLMG 204
Query: 123 QLSAMQINSYGSGMAPPSQGPPGPLSATSLQTPPRPPQPSILQPGSQVLPPPPTTLNGPG 182
+ M QGP G LQ PP PP Q Q P G
Sbjct: 205 PPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPG----QISEQKRPIDVEFQKGDQ 260
Query: 183 ASPLPLPMYRPDGLSGPPPPNAQYQPPPLPGQTLGAGYPPQQANSGPQMAGAQLSYPG-- 240
P P G+ GPP P P G+ G P ++ G Q PG
Sbjct: 261 GLPGDRGPPGPPGIRGPPGP-----PGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLP 315
Query: 241 ---GFPGGPAQ--------MAGPPQP 255
G+PG P + GPP P
Sbjct: 316 GDPGYPGEPGRDGEKGQKGDTGPPGP 341
Score = 52.4 bits (124), Expect = 2e-06
Identities = 84/304 (27%), Positives = 106/304 (34%), Gaps = 53/304 (17%)
Query: 4 QGYVATP-----PYSQPQPGIGLSPPHYGHYGDPSHTASPTGMMKPAGPLGATATRGMLP 58
+GY P P QPG+ PP G G+P P G++ P G G G
Sbjct: 981 KGYQGLPGDPGQPGLSGQPGLP-GPP--GPKGNPGLPGQP-GLIGPPGLKGTIGDMGF-- 1034
Query: 59 PGPP----PPGPHQF-GQNGAHATGHPPQRFP-GPPPVNNVASSHAPYQPSAQSSYPG-- 110
PGP PPGP GQ G+ G P Q+ G P ++++ P P + PG
Sbjct: 1035 PGPQGVEGPPGPSGVPGQPGS--PGLPGQKGDKGDPGISSIGLPGLP-GPKGEPGLPGYP 1091
Query: 111 --PISTSSVTQLGSQLSAMQINSYGSGMAPPSQGPPGPLSATSLQTPPRPP----QPSIL 164
P SV G + G P G PGP + PP P +P +
Sbjct: 1092 GNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPV 1151
Query: 165 QPGSQV-LPPPPTTLNGPGASPLPLPMYRPD-----GLSGPPPPNAQYQPPPLPGQTLGA 218
G P PP PG +P P + G P PP P L GQ
Sbjct: 1152 GGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGL----PGLSGQKGDG 1207
Query: 219 GYPPQQANSG---PQMAGAQLSYPG--------GFPG----GPAQMAGPPQPQKKLDPDS 263
G P N G P+ +PG G PG GP GP P +
Sbjct: 1208 GLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQG 1267
Query: 264 IPSP 267
+P P
Sbjct: 1268 LPGP 1271
Score = 51.2 bits (121), Expect = 5e-06
Identities = 92/328 (28%), Positives = 107/328 (32%), Gaps = 88/328 (26%)
Query: 17 PGIGLSPPHYGHYGDPSHTASP--TGMMKPAGPLGATATRGMLPPGP-----PPPGPHQF 69
PG +P G GDP P G G G T G PPGP PP P
Sbjct: 1088 PGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPG--PPGPKGISGPPGNPGLP 1145
Query: 70 GQNG-AHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGSQLSAMQ 128
G+ G GHP Q PGPP P+ Q PG + G + Q
Sbjct: 1146 GEPGPVGGGGHPGQ--PGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQ 1203
Query: 129 INSYGSGMAPPSQGPPGPLSATS------LQTPPRPP----------------QPSILQP 166
G P + G PGP +Q PP PP Q +P
Sbjct: 1204 KGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRP 1263
Query: 167 GSQVLP----PPPTTLNG--------PGASPLP-LPMYRPD-------GLSGPPPPNAQY 206
G Q LP PP NG PG LP LP + D G G P N
Sbjct: 1264 GFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMK 1323
Query: 207 QPPPLPGQTLGAGYPPQQANSG-PQMAGAQ-----LSYPG-------------------- 240
P LPG G+P + SG P AG + + PG
Sbjct: 1324 GDPGLPGVP---GFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGP 1380
Query: 241 -GFPGGPAQMAGPPQPQKKLDPDSIPSP 267
G PG P + G P PQ P +P P
Sbjct: 1381 PGIPGQPG-LKGLPGPQ---GPQGLPGP 1404
Score = 47.4 bits (111), Expect = 7e-05
Identities = 44/144 (30%), Positives = 51/144 (35%), Gaps = 26/144 (18%)
Query: 138 PPSQGPPGPLSATSLQTPPRPPQPSILQ--PGSQVLPPPPTTLNGPGASPLPLPMYRP-- 193
P +GPPGP P PP P ++ PG P P PG P P P
Sbjct: 65 PGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGC 124
Query: 194 ---------------DGLSGPPPPNAQYQPPPLPGQTLGAGYPPQQANSG-PQMAGAQ-L 236
GL GPP P PG + + P + N G P G Q L
Sbjct: 125 NGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGL 184
Query: 237 SYPGGFPG-----GPAQMAGPPQP 255
P G PG GP + GPP P
Sbjct: 185 PGPTGIPGPIGPPGPPGLMGPPGP 208
Score = 47.4 bits (111), Expect = 7e-05
Identities = 50/175 (28%), Positives = 65/175 (37%), Gaps = 14/175 (8%)
Query: 10 PPYSQPQPGIGLSPPHYGHYGDPSHTASP--TGMMKPAGPLGATATRG----MLPPGPPP 63
PP Q PG P G GDP P GM P+G G+ G + PPGPP
Sbjct: 1307 PPGLQGNPG---RPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPG 1363
Query: 64 -PGPHQFGQNGAHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGS 122
PGP GQ+ P PG P + + P + PG + + G
Sbjct: 1364 LPGPS--GQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLP--GF 1419
Query: 123 QLSAMQINSYGSGMAPPSQGPPGPLSATSLQTPPRPPQPSILQPGSQVLPPPPTT 177
+ + G P ++G GP LQ PP PP S + G + TT
Sbjct: 1420 DGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTT 1474
Score = 45.8 bits (107), Expect = 2e-04
Identities = 65/247 (26%), Positives = 84/247 (34%), Gaps = 44/247 (17%)
Query: 23 PPHYGHYGDPSHTASPTGMMKPAGPLGATATRGMLPPGPP----PPGPHQFGQNGAHATG 78
PP G G S P + G G RG PPGPP PPGP + G
Sbjct: 237 PP--GPPGQISEQKRPIDVEFQKGDQGLPGDRG--PPGPPGIRGPPGPPGGEKGEKGEQG 292
Query: 79 HPPQR----------------FPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGS 122
P +R PG P + PGP + + G+
Sbjct: 293 EPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLV-IPRPGT 351
Query: 123 QLSAMQINSYGSGMAPPSQGPPGPLSATSLQTPPRPPQPSILQPGSQVLPPPPTTLNGPG 182
++ I G+ P G G +Q PP P P PG+ V+ PP GP
Sbjct: 352 GIT---IGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGP----PGAAVMGPP-----GPP 399
Query: 183 ASPLPLPMYRPDGLSGPPPPNAQYQPPPLPGQTLGAGYPPQQANSGPQMAGA-QLSYPG- 240
P +G G P PP L GQ G P +GP + + ++ PG
Sbjct: 400 GFPGERGQKGDEGPPGISIPG----PPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGP 455
Query: 241 -GFPGGP 246
G PG P
Sbjct: 456 PGPPGSP 462
Score = 44.7 bits (104), Expect = 5e-04
Identities = 74/276 (26%), Positives = 90/276 (32%), Gaps = 48/276 (17%)
Query: 11 PYSQPQPGIGLSPPHYGHYGDPSHTA----SPTGMMKPAGPLGATATRGMLPPGPPPPGP 66
P + +PG P G G P P G P GP G +G+ P PP P
Sbjct: 1219 PGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLP 1278
Query: 67 HQFGQNGAHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQL------ 120
G G G+P Q PG P + + P PG L
Sbjct: 1279 GNGGIKGEK--GNPGQ--PGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGF 1334
Query: 121 -GSQLSAMQINSYGSGMAPPSQGPPGP--LSATSLQT---------PPRPPQPSIL---- 164
G + + S G P GPPGP L S Q+ P P QP +
Sbjct: 1335 PGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPG 1394
Query: 165 QPGSQVLPPPPTTLNGPGASPLP-------------LP-MYRPDGLSGPPPPNAQYQPPP 210
G Q LP P PG + LP LP GL GPP P+ PP
Sbjct: 1395 PQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPG 1454
Query: 211 LPG-QTLGAGY---PPQQANSGPQMAGAQLSYPGGF 242
PG ++ G+ Q PQ L GF
Sbjct: 1455 PPGTSSVAHGFLITRHSQTTDAPQCPQGTLQVYEGF 1490
>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
sapiens]
Length = 309
Score = 72.8 bits (177), Expect = 2e-12
Identities = 75/246 (30%), Positives = 89/246 (36%), Gaps = 39/246 (15%)
Query: 32 PSHTASPTGMMKPAGPLGATATRGMLPPGPPPPGPHQFGQNGAHATGHPPQRFPGPPPVN 91
P T P G + P G ++G P P GP G N + P + G PP
Sbjct: 47 PQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQG 106
Query: 92 NVASSHAPYQPSAQSSYPGPISTSSVTQLGSQLSAMQINSYGSGMAP-PSQGPPGPLSAT 150
S P +P P Q G+Q S G P +GPP
Sbjct: 107 GNQSQGPPPRPGKPEGPP--------PQGGNQ-------SQGPPPRPGKPEGPPPQGGNQ 151
Query: 151 SLQTPPRPPQPSILQP----GSQVLPPPPTTLNGP---GASPLPLPMYRPDGLSGPPPP- 202
S PPRP +P P SQ PP P GP G + P RP GPPP
Sbjct: 152 SQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQG 211
Query: 203 -NAQYQPPPLPGQTLGAGYPPQQANSGPQMAGAQLSYPGGFPGGPAQMAGPPQPQKKLDP 261
N PPP PG+ G PP Q + PQ G P P + GPP PQ+ P
Sbjct: 212 GNQSQGPPPRPGKPEG---PPSQGGNKPQ----------GPPPHPGKPQGPP-PQEGNKP 257
Query: 262 DSIPSP 267
P P
Sbjct: 258 QRPPPP 263
Score = 63.5 bits (153), Expect = 1e-09
Identities = 75/248 (30%), Positives = 84/248 (33%), Gaps = 61/248 (24%)
Query: 15 PQPGIGLSPPHYG---HYGDPSHTASPTGMMKPAGPLGATATRGMLPPGPPPPGPHQFGQ 71
P+PG PP G G P P G P G ++G P P GP G
Sbjct: 115 PRPGKPEGPPPQGGNQSQGPPPRPGKPEG----PPPQGGNQSQGPPPRPGKPEGPPPQGG 170
Query: 72 NGAHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGSQLSAMQINS 131
N + P + GPPP S P +P P Q G+Q
Sbjct: 171 NQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPP--------PQGGNQSQGPPPRP 222
Query: 132 YGSGMAPPSQG---PPGPLSATSLQTPPRPPQPSILQPGSQVLPPPPTTLNGPGASPLPL 188
G PPSQG P GP PP P +P PPP N P P
Sbjct: 223 -GKPEGPPSQGGNKPQGP--------PPHPGKPQ---------GPPPQEGNKPQRPP--- 261
Query: 189 PMYRPDGLSGPPPP--NAQYQPPPLPGQTLGAGYPPQQANSGPQMAGAQLSYPGGFPGGP 246
P RP G PPPP N Q PP G+ G PPQ GG P P
Sbjct: 262 PPGRPQG---PPPPGGNPQQPLPPPAGKPQGPPPPPQ----------------GGRPHRP 302
Query: 247 AQMAGPPQ 254
Q PPQ
Sbjct: 303 PQ-GQPPQ 309
Score = 61.2 bits (147), Expect = 5e-09
Identities = 73/254 (28%), Positives = 84/254 (33%), Gaps = 43/254 (16%)
Query: 15 PQPGIGLSPPHYG---HYGDPSHTASPTGMMKPAGPLGATATRGMLPPGPPPPGPHQFGQ 71
P+PG PP G G P P G P G ++G P P GP G
Sbjct: 73 PRPGKPEGPPPQGGNQSQGPPPRPGKPEGQP----PQGGNQSQGPPPRPGKPEGPPPQGG 128
Query: 72 NGAHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYP---GPISTSSVTQLGSQLSAMQ 128
N + P + GPPP S P +P P G S G
Sbjct: 129 NQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPP 188
Query: 129 INSYGSGMAPPS----QGPPGPLSATSLQTPPRPPQPS--ILQPGSQVLPPPPTTLNGPG 182
S PP +GPP S PPRP +P Q G++ PPP G
Sbjct: 189 QGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHP--GKP 246
Query: 183 ASPLPLPMYRPDGLSGPPPPNAQYQPPPLPGQTLGAGYPPQQANSGPQMAGAQLSYPGGF 242
P P +P PPPP PPP G PQQ L P G
Sbjct: 247 QGPPPQEGNKPQR---PPPPGRPQGPPPPGGN-------PQQ----------PLPPPAGK 286
Query: 243 PGGPAQMAGPPQPQ 256
P GP PP PQ
Sbjct: 287 PQGP-----PPPPQ 295
>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
Length = 638
Score = 71.6 bits (174), Expect = 4e-12
Identities = 89/299 (29%), Positives = 108/299 (36%), Gaps = 77/299 (25%)
Query: 2 SQQGYVATPPYSQPQPGIGLSPPHYGHYGDPSHTASPTGMMKP---AGPLGATATRGMLP 58
S G TP S P+P + P P S T P +GP + GM
Sbjct: 331 STSGPATTPLASAPRPAAPANNP------PPPSLMSTTQSRPPWMNSGPSESRPYHGMHG 384
Query: 59 PGPPPPG--PHQF--------GQNGAHATGH------PPQRFPGPPPVNNVASSHAPYQP 102
GP PG PH F G +G H H PP P PPP+N + P
Sbjct: 385 GGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGP 444
Query: 103 SAQSSYPGPISTSSVTQLGSQLSAMQINSYGSGMAPPSQGPPGPLSATSLQTPPRPPQPS 162
Y G T +GS + + G GM PP P G + PP PP PS
Sbjct: 445 PPMDQYLGS------TPVGSGVYRLH---QGKGMMPPP--PMGMM-------PPPPPPPS 486
Query: 163 ILQPGSQVLPPPPTTLNGPGASPLPLPMYRPDGLSGPPPP---NAQYQPPPLPGQ----- 214
QP PPPP+ PLP ++ PPPP ++ PLP Q
Sbjct: 487 G-QP-----PPPPSG---------PLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTT 531
Query: 215 -TLGAG---YPPQQANSGPQMAGAQLSYPGG--FPGGPAQMAGPPQPQKKLDPDSIPSP 267
T AG PP Q Q A + PG G P + PP Q L P + P P
Sbjct: 532 TTTSAGTGSIPPWQ-----QQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPP 585
Score = 62.0 bits (149), Expect = 3e-09
Identities = 70/227 (30%), Positives = 97/227 (42%), Gaps = 48/227 (21%)
Query: 10 PPYSQPQPGIGLSPPHY-GHYGDPSHTASPTGMMKPAGPLGATATR-----GMLPPGP-- 61
PP+ QP P PH GH+G P P + P+G+ R GM+PP P
Sbjct: 422 PPWMQPPPPPMNQGPHPPGHHGPP-----PMDQYLGSTPVGSGVYRLHQGKGMMPPPPMG 476
Query: 62 --PPPGPHQFGQNGAHATGHPP-------QRFPGPPPVNNVASSHA-PYQPSAQSSYPGP 111
PPP P GQ +G P Q P PPP +++ASS P+Q + ++
Sbjct: 477 MMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTT---- 532
Query: 112 ISTSSVTQLGSQLSAMQINSYGSGMAPPSQGPPGPLSATSLQTPP--RPPQPSILQPGSQ 169
+TS+ T Q + S AP QG P T + PP +PP P PG+
Sbjct: 533 -TTSAGTGSIPPWQQQQAAAAASPGAPQMQGNP-----TMVPLPPGVQPPLP----PGA- 581
Query: 170 VLPPPPTTLNGPGASPLPLPMYRPDGLSGPPPPNAQYQPP--PLPGQ 214
PPP PG++ + +P P G GP + + P LPG+
Sbjct: 582 ---PPPPPPPPPGSAGMMIP---PRGGDGPSHESEDFPRPLVTLPGR 622
Score = 38.9 bits (89), Expect = 0.025
Identities = 51/193 (26%), Positives = 60/193 (31%), Gaps = 49/193 (25%)
Query: 122 SQLSAMQINSYGSGMAPPSQGPPGPLSATSLQTPPRPPQPSILQPGSQVLPPPPTTL--- 178
+Q A Y S MA + P P S S P P S +P + PPP +L
Sbjct: 303 AQDKARMDKEYLSLMAELGEAPV-PASVGSTSGPATTPLASAPRPAAPANNPPPPSLMST 361
Query: 179 --------------------------NGPGASPLPLPMYRPD------------GLSGPP 200
GPG P P P +GPP
Sbjct: 362 TQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPP 421
Query: 201 PPNAQYQPPPL---PGQTLGAGYPP--QQANSGPQMAGAQLSYPGG--FPGGPAQMAGPP 253
PP Q PPP+ P G PP Q S P +G + G P P M PP
Sbjct: 422 PPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPP 481
Query: 254 QPQKKLDPDSIPS 266
P P PS
Sbjct: 482 PPPPSGQPPPPPS 494
>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
Length = 639
Score = 71.6 bits (174), Expect = 4e-12
Identities = 89/299 (29%), Positives = 108/299 (36%), Gaps = 77/299 (25%)
Query: 2 SQQGYVATPPYSQPQPGIGLSPPHYGHYGDPSHTASPTGMMKP---AGPLGATATRGMLP 58
S G TP S P+P + P P S T P +GP + GM
Sbjct: 331 STSGPATTPLASAPRPAAPANNP------PPPSLMSTTQSRPPWMNSGPSESRPYHGMHG 384
Query: 59 PGPPPPG--PHQF--------GQNGAHATGH------PPQRFPGPPPVNNVASSHAPYQP 102
GP PG PH F G +G H H PP P PPP+N + P
Sbjct: 385 GGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGP 444
Query: 103 SAQSSYPGPISTSSVTQLGSQLSAMQINSYGSGMAPPSQGPPGPLSATSLQTPPRPPQPS 162
Y G T +GS + + G GM PP P G + PP PP PS
Sbjct: 445 PPMDQYLGS------TPVGSGVYRLH---QGKGMMPPP--PMGMM-------PPPPPPPS 486
Query: 163 ILQPGSQVLPPPPTTLNGPGASPLPLPMYRPDGLSGPPPP---NAQYQPPPLPGQ----- 214
QP PPPP+ PLP ++ PPPP ++ PLP Q
Sbjct: 487 G-QP-----PPPPSG---------PLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTT 531
Query: 215 -TLGAG---YPPQQANSGPQMAGAQLSYPGG--FPGGPAQMAGPPQPQKKLDPDSIPSP 267
T AG PP Q Q A + PG G P + PP Q L P + P P
Sbjct: 532 TTTSAGTGSIPPWQ-----QQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPP 585
Score = 38.9 bits (89), Expect = 0.025
Identities = 51/193 (26%), Positives = 60/193 (31%), Gaps = 49/193 (25%)
Query: 122 SQLSAMQINSYGSGMAPPSQGPPGPLSATSLQTPPRPPQPSILQPGSQVLPPPPTTL--- 178
+Q A Y S MA + P P S S P P S +P + PPP +L
Sbjct: 303 AQDKARMDKEYLSLMAELGEAPV-PASVGSTSGPATTPLASAPRPAAPANNPPPPSLMST 361
Query: 179 --------------------------NGPGASPLPLPMYRPD------------GLSGPP 200
GPG P P P +GPP
Sbjct: 362 TQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPP 421
Query: 201 PPNAQYQPPPL---PGQTLGAGYPP--QQANSGPQMAGAQLSYPGG--FPGGPAQMAGPP 253
PP Q PPP+ P G PP Q S P +G + G P P M PP
Sbjct: 422 PPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPP 481
Query: 254 QPQKKLDPDSIPS 266
P P PS
Sbjct: 482 PPPPSGQPPPPPS 494
>gi|54860079 nadrin isoform 1 [Homo sapiens]
Length = 881
Score = 71.6 bits (174), Expect = 4e-12
Identities = 66/216 (30%), Positives = 83/216 (38%), Gaps = 48/216 (22%)
Query: 33 SHTASPTGMMKPAGPLGATATRGMLPPGPPPPGP------HQFGQNGAHATGHPPQRFPG 86
SH S AGP T R + P P PP P H GQ+ + + HPP P
Sbjct: 610 SHQLSMGQPHNAAGPSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPK 669
Query: 87 PPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGSQLSAMQINSYGSGMAPP------- 139
PP + + QP Q S P + S+ + S LS +Q ++ P
Sbjct: 670 PPTRSPSPPTQHTGQPPGQPSAPSQL--SAPRRYSSSLSPIQAPNHPPPQPPTQATPLMH 727
Query: 140 ----SQGPPGPLSATS-------LQTPPRPPQPSILQPGSQVLP--PPPTTLNG------ 180
SQGPP P++ S TPP+ P P P + P P P TL G
Sbjct: 728 TKPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLAGGNPETA 787
Query: 181 -------PGASPLPLPMYRPDGLSGPPPPNAQYQPP 209
P P+P P RP S PPPP QPP
Sbjct: 788 QPHAGTLPRPRPVPKPRNRP---SVPPPP----QPP 816
Score = 47.0 bits (110), Expect = 9e-05
Identities = 44/167 (26%), Positives = 58/167 (34%), Gaps = 14/167 (8%)
Query: 2 SQQGYVATPPYSQPQPGIGLSPPHYGHYGDPSHTASPTGMMKPAGPLGATATRGMLPPGP 61
S G PP P+P P H G P S + ++ + P P
Sbjct: 655 SSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPGQPSAPSQLSAPRRYSSSLSPIQAPNHP 714
Query: 62 PPPGPHQFGQNGAHATGHPPQRFPGPPPVNNVASSHAPYQPS-AQSSYPGPISTSSVTQL 120
PP P Q A H GPP + S H QPS P P ST + +
Sbjct: 715 PPQPPTQ-----ATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQ 769
Query: 121 GSQLSAMQINSYG--------SGMAPPSQGPPGPLSATSLQTPPRPP 159
L A Q + G +G P + P P + S+ PP+PP
Sbjct: 770 NPSLPAPQTLAGGNPETAQPHAGTLPRPRPVPKPRNRPSVPPPPQPP 816
Score = 42.7 bits (99), Expect = 0.002
Identities = 56/231 (24%), Positives = 79/231 (34%), Gaps = 42/231 (18%)
Query: 49 GATATRGMLPPGPPPPGPHQFGQNGAHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSY 108
G T R + P PP P G A P PPP ++ A S SS
Sbjct: 511 GGTLNRKHISPAFQPPLPPTDGSTVVPAG-------PEPPPQSSRAES---------SSG 554
Query: 109 PGPI-STSSVTQLGSQLSAMQINSYGSGMAPPSQGP-----PGPLSATSLQTPPRPPQPS 162
G + S++ + + G S G G P + P P P + Q QP
Sbjct: 555 GGTVPSSAGILEQGP--------SPGDGSPPKPKDPVSAAVPAP-GRNNSQIASGQNQPQ 605
Query: 163 ILQPGSQVLPPPPTTLNGPGASPLPLPMYRPDGLSGPPPPNAQYQPPPLPGQTLGAG--- 219
Q+ P GP L + +P P PP PP PG +G
Sbjct: 606 AAAGSHQLSMGQPHNAAGPSPHTLRRAVKKP----APAPPKPGNPPPGHPGGQSSSGTSQ 661
Query: 220 YPPQQANSGPQMAGA----QLSYPGGFPGGPAQMAGPPQPQKKLDPDSIPS 266
+PP + P + + P G P P+Q++ P + L P P+
Sbjct: 662 HPPSLSPKPPTRSPSPPTQHTGQPPGQPSAPSQLSAPRRYSSSLSPIQAPN 712
Score = 40.0 bits (92), Expect = 0.011
Identities = 57/223 (25%), Positives = 78/223 (34%), Gaps = 23/223 (10%)
Query: 102 PSAQSSYPGPISTSSVTQLGSQ---LSAMQINSYGSGMAPPSQG--PPGPLSATSLQTPP 156
P+ Q P P S+V G + S+ +S G G P S G GP +PP
Sbjct: 521 PAFQPPLP-PTDGSTVVPAGPEPPPQSSRAESSSGGGTVPSSAGILEQGPSPGDG--SPP 577
Query: 157 RPPQP---SILQPG---SQVLPPPPTTLNGPGASPLPLPMYRPDGLSGPPPPN---AQYQ 207
+P P ++ PG SQ+ G+ L M +P +GP P A +
Sbjct: 578 KPKDPVSAAVPAPGRNNSQIASGQNQPQAAAGSHQLS--MGQPHNAAGPSPHTLRRAVKK 635
Query: 208 PPPLPGQTLGAGYPPQQANSGPQMAGAQLSYPGGFPGGPAQMAGPPQPQKKLDPDSIPSP 267
P P P + G PP G +G P P P + PP P +P
Sbjct: 636 PAPAPPKP---GNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPGQPSAP 692
Query: 268 IQVIENDRASRG-GQVYATNTRGQIPPLVTTDCMIQDQGNASP 309
Q+ R S + A N PP T M + P
Sbjct: 693 SQLSAPRRYSSSLSPIQAPNHPPPQPPTQATPLMHTKPNSQGP 735
Score = 33.5 bits (75), Expect = 1.1
Identities = 19/65 (29%), Positives = 26/65 (40%), Gaps = 2/65 (3%)
Query: 8 ATPPYSQPQPGIGLSPPHYGHYGDPSHTASPTGMMKPAGPLGATATRGMLPPGPPPPGPH 67
+TPP + P L P G+P G + P+ R +PP P PPG H
Sbjct: 762 STPPLGKQNPS--LPAPQTLAGGNPETAQPHAGTLPRPRPVPKPRNRPSVPPPPQPPGVH 819
Query: 68 QFGQN 72
G +
Sbjct: 820 SAGDS 824
>gi|54860105 nadrin isoform 2 [Homo sapiens]
Length = 803
Score = 71.6 bits (174), Expect = 4e-12
Identities = 66/216 (30%), Positives = 83/216 (38%), Gaps = 48/216 (22%)
Query: 33 SHTASPTGMMKPAGPLGATATRGMLPPGPPPPGP------HQFGQNGAHATGHPPQRFPG 86
SH S AGP T R + P P PP P H GQ+ + + HPP P
Sbjct: 532 SHQLSMGQPHNAAGPSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPK 591
Query: 87 PPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGSQLSAMQINSYGSGMAPP------- 139
PP + + QP Q S P + S+ + S LS +Q ++ P
Sbjct: 592 PPTRSPSPPTQHTGQPPGQPSAPSQL--SAPRRYSSSLSPIQAPNHPPPQPPTQATPLMH 649
Query: 140 ----SQGPPGPLSATS-------LQTPPRPPQPSILQPGSQVLP--PPPTTLNG------ 180
SQGPP P++ S TPP+ P P P + P P P TL G
Sbjct: 650 TKPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLAGGNPETA 709
Query: 181 -------PGASPLPLPMYRPDGLSGPPPPNAQYQPP 209
P P+P P RP S PPPP QPP
Sbjct: 710 QPHAGTLPRPRPVPKPRNRP---SVPPPP----QPP 738
Score = 47.0 bits (110), Expect = 9e-05
Identities = 44/167 (26%), Positives = 58/167 (34%), Gaps = 14/167 (8%)
Query: 2 SQQGYVATPPYSQPQPGIGLSPPHYGHYGDPSHTASPTGMMKPAGPLGATATRGMLPPGP 61
S G PP P+P P H G P S + ++ + P P
Sbjct: 577 SSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPGQPSAPSQLSAPRRYSSSLSPIQAPNHP 636
Query: 62 PPPGPHQFGQNGAHATGHPPQRFPGPPPVNNVASSHAPYQPS-AQSSYPGPISTSSVTQL 120
PP P Q A H GPP + S H QPS P P ST + +
Sbjct: 637 PPQPPTQ-----ATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQ 691
Query: 121 GSQLSAMQINSYG--------SGMAPPSQGPPGPLSATSLQTPPRPP 159
L A Q + G +G P + P P + S+ PP+PP
Sbjct: 692 NPSLPAPQTLAGGNPETAQPHAGTLPRPRPVPKPRNRPSVPPPPQPP 738
Score = 37.0 bits (84), Expect = 0.096
Identities = 33/136 (24%), Positives = 47/136 (34%), Gaps = 12/136 (8%)
Query: 138 PPSQGPPGPLSATSLQTPPRPPQPSILQPGSQVLPPPPTTLNGPGASPLPLPMYRPDGLS 197
P S P P + Q QP Q+ P GP L + +P
Sbjct: 504 PVSAAVPAP-GRNNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPHTLRRAVKKP---- 558
Query: 198 GPPPPNAQYQPPPLPGQTLGAG---YPPQQANSGPQMAGA----QLSYPGGFPGGPAQMA 250
P PP PP PG +G +PP + P + + P G P P+Q++
Sbjct: 559 APAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPGQPSAPSQLS 618
Query: 251 GPPQPQKKLDPDSIPS 266
P + L P P+
Sbjct: 619 APRRYSSSLSPIQAPN 634
Score = 35.0 bits (79), Expect = 0.37
Identities = 41/167 (24%), Positives = 58/167 (34%), Gaps = 15/167 (8%)
Query: 153 QTPPRPPQP---SILQPG---SQVLPPPPTTLNGPGASPLPLPMYRPDGLSGPPPPN--- 203
++PP+P P ++ PG SQ+ G+ L M +P +GP P
Sbjct: 496 ESPPKPKDPVSAAVPAPGRNNSQIASGQNQPQAAAGSHQLS--MGQPHNAAGPSPHTLRR 553
Query: 204 AQYQPPPLPGQTLGAGYPPQQANSGPQMAGAQLSYPGGFPGGPAQMAGPPQPQKKLDPDS 263
A +P P P + G PP G +G P P P + PP P
Sbjct: 554 AVKKPAPAPPKP---GNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPGQ 610
Query: 264 IPSPIQVIENDRASRG-GQVYATNTRGQIPPLVTTDCMIQDQGNASP 309
+P Q+ R S + A N PP T M + P
Sbjct: 611 PSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPTQATPLMHTKPNSQGP 657
Score = 33.5 bits (75), Expect = 1.1
Identities = 19/65 (29%), Positives = 26/65 (40%), Gaps = 2/65 (3%)
Query: 8 ATPPYSQPQPGIGLSPPHYGHYGDPSHTASPTGMMKPAGPLGATATRGMLPPGPPPPGPH 67
+TPP + P L P G+P G + P+ R +PP P PPG H
Sbjct: 684 STPPLGKQNPS--LPAPQTLAGGNPETAQPHAGTLPRPRPVPKPRNRPSVPPPPQPPGVH 741
Query: 68 QFGQN 72
G +
Sbjct: 742 SAGDS 746
>gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3
[Homo sapiens]
Length = 1125
Score = 71.2 bits (173), Expect = 5e-12
Identities = 83/290 (28%), Positives = 111/290 (38%), Gaps = 89/290 (30%)
Query: 17 PGIGLSPPHYGHYGDPSHTASPTGMMKPAGPLGATATRGMLPPGPPPPGPHQFGQNGAHA 76
P +G+ PP +G G P P + P+ G LPPGPPPP
Sbjct: 702 PPLGIPPPGFGP-GVPPPPPPPPFLRPGFNPMHLPP--GFLPPGPPPPIT---------- 748
Query: 77 TGHPPQRFPGP--PPVN----------------NVASSHAPYQPSAQSSYPGPISTSSVT 118
PP P P PP++ +V + P+A ++ P P T V+
Sbjct: 749 ---PPVSIPPPHTPPISIPNLVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVS 805
Query: 119 QLGSQ------LSAMQINSYGS-GMAP---PSQGPPGPLSATSLQT----PPRPPQPSIL 164
LG+Q + +Q S G G P P Q PPG + LQ PPRP P ++
Sbjct: 806 LLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPG-MPPPHLQRFPLMPPRPMPPHMM 864
Query: 165 QPGSQVLPPPPTTLNGPGASPLPLPMYRPDGLSGPPPPNAQY-QPPPLPGQTLGAGYPPQ 223
G PPP GPG +P P G+ GP PP+ + +P +PG
Sbjct: 865 HRG-----PPP----GPGGFAMP----PPHGMKGPFPPHGPFVRPGGMPG---------- 901
Query: 224 QANSGPQMAGAQLSYPGGFPGGPAQMAG----PPQPQKKLDPDSIPSPIQ 269
L PG PGGP G P QPQ++ P + P Q
Sbjct: 902 ------------LGGPGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQ 939
Score = 45.4 bits (106), Expect = 3e-04
Identities = 58/220 (26%), Positives = 81/220 (36%), Gaps = 45/220 (20%)
Query: 60 GPPPPGPHQFGQNGAHATGHP------PQRFPGPPPVNNVASSHAPYQPSAQSSYPGPIS 113
G P ++ QNG T H P+ P P P V + P PGP
Sbjct: 632 GIPKKPENEVAQNGGAETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGP-- 689
Query: 114 TSSVTQLGSQLSAMQINSYGS--GMAPPSQGPPGPLSATSLQTPPRPPQPSILQPGSQVL 171
+ A+Q ++ G+ PP GP PP PP P L+PG +
Sbjct: 690 --------PVVGALQPPAFTPPLGIPPPGFGPG---------VPPPPPPPPFLRPGFNPM 732
Query: 172 PPPPTTLNGPGASPLPLPMYRPDGLSGPPPPNAQYQPPPLPGQTLGAGYPPQQANSGPQM 231
PP L PG P P+ P + PPP+ P +P GA + +S +M
Sbjct: 733 HLPPGFL-PPGPPP---PITPPVSI---PPPHT--PPISIPNLVSGARGNAESGDS-VKM 782
Query: 232 AGAQLSYPGGFPGGPAQMAGPP--QPQKKLDPDSI-PSPI 268
G+ + P P + PP QP L + P P+
Sbjct: 783 YGSAVP-----PAAPTNLPTPPVTQPVSLLGTQGVAPGPV 817
Score = 33.9 bits (76), Expect = 0.81
Identities = 51/196 (26%), Positives = 59/196 (30%), Gaps = 69/196 (35%)
Query: 9 TPPYSQPQ-----------PGIGLSPPHYGHYGDPSHTASP--TGMMKPAG-PLGATATR 54
TPP +QP P IGL P G G A P + +P G P
Sbjct: 797 TPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLG-----ARPGLIPLQRPPGMPPPHLQRF 851
Query: 55 GMLPPGP---------PPPGPHQFGQNGAHATGHPPQRFPGPPPVNNVASSHAPY-QPSA 104
++PP P PPPGP F PP GP P H P+ +P
Sbjct: 852 PLMPPRPMPPHMMHRGPPPGPGGFAMP-------PPHGMKGPFP------PHGPFVRPGG 898
Query: 105 QSSYPGPISTSSVTQLGSQLSAMQINSYGSGMAPPS------QGPPGPLSATSLQTPPRP 158
GP G G P Q P P Q P +P
Sbjct: 899 MPGLGGP---------------------GPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQP 937
Query: 159 PQPSILQPGSQVLPPP 174
Q QP PPP
Sbjct: 938 QQQQQQQPPPSQQPPP 953
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 70.9 bits (172), Expect = 6e-12
Identities = 72/262 (27%), Positives = 90/262 (34%), Gaps = 29/262 (11%)
Query: 8 ATPPYSQPQPGIGLSPPHYGHYGDPSHTASPTGMMKPAGPLGATATRGMLPPGPPPPGPH 67
+ PP Q P +PP S T T P+ PL AT PPP P
Sbjct: 346 SAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLAT-------PPPQAPP 398
Query: 68 QFGQNGAHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSY--PGPISTSSVTQLGSQLS 125
A PP PP++ +A+ +P P+A + + P S + + S
Sbjct: 399 ALALPPLQAPPSPP----ASPPLSPLATP-SPQAPNALAVHLLQAPFSPPPSPPVQAPFS 453
Query: 126 AMQINSYGSGMAPPSQGPPGPLSATSLQTPPRPPQPSILQPGSQVLPPPPTTLNGPGASP 185
PPSQ PP L+A LQ PP PP + P + P P L P
Sbjct: 454 PPASPPVSPSATPPSQAPPS-LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL 512
Query: 186 LPLPMYRPDGLSGPPPPNAQYQPPPLPGQT----------LGAGYPPQQANSGPQMAGAQ 235
P P L+ PP P PGQ PP QA P +A
Sbjct: 513 AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQA--PPVLAAPL 570
Query: 236 LSYPGGFPGGPAQMA--GPPQP 255
L P P P A PP P
Sbjct: 571 LQVPPSPPASPTLQAPRRPPTP 592
Score = 60.1 bits (144), Expect = 1e-08
Identities = 85/320 (26%), Positives = 110/320 (34%), Gaps = 80/320 (25%)
Query: 9 TPPYSQPQPGIG-LSPPHYGHYGDPSHTASPTGMMK-------PAGPLGATATRGMLPPG 60
TPP P +G LS P T SP+ ++ PA P ++ T + P
Sbjct: 286 TPPRKDAAPALGPLS-------SSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPL 338
Query: 61 P-PPPGPHQFGQNGAHATGHPP--QRFPGPP---PVNNVASSHAPYQPSAQSSYPGPIST 114
P PP P PP Q P PP P S +P + S P P +
Sbjct: 339 PLAPPSPSA-----------PPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLS 387
Query: 115 SSVTQLGSQLSAMQINSYGSGMAPPSQGPPGPLSATSLQTPPRPPQPSILQPGSQVLPPP 174
T PP Q PP L+ LQ PP PP P S + P
Sbjct: 388 PLAT-------------------PPPQAPPA-LALPPLQAPPSPPA---SPPLSPLATPS 424
Query: 175 PTTLNGPGASPLPLPMYRPDGLSGPPPPNAQYQPPPLPGQTLGAGYPPQQANSGPQMAGA 234
P N L P P PP A + PP P + A PP QA P +A
Sbjct: 425 PQAPNALAVHLLQAPFSPPPS----PPVQAPFSPPASPPVSPSA-TPPSQA--PPSLAAP 477
Query: 235 QLSYPGGFPGGPAQ-------------MAGPPQPQKKLDPDSIPS----PIQVIENDRAS 277
L P P P +A PP K P + P+ P+Q + + AS
Sbjct: 478 PLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPAS 537
Query: 278 RGGQV-YATNTRGQIPPLVT 296
GQ ++ + + PL T
Sbjct: 538 FPGQAPFSPSASLPMSPLAT 557
Score = 57.4 bits (137), Expect = 7e-08
Identities = 75/287 (26%), Positives = 95/287 (33%), Gaps = 46/287 (16%)
Query: 8 ATPPYSQPQPGIGLSPPHYGHYGDPSHTASPTGMMKPAGPLGATATRGMLPPGPP----- 62
ATPP SQ +G H PS SP P P PP PP
Sbjct: 359 ATPP-SQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPL 417
Query: 63 -------PPGPHQFGQNGAHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTS 115
P P+ + A PP P P + AS P PSA P S +
Sbjct: 418 SPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP--PVSPSATPPSQAPPSLA 475
Query: 116 S----VTQLGSQLSAMQINSYGSGMAPPS-QGPPGPLSATSLQTPPRPPQPSILQPGSQV 170
+ V M ++ APP PP L PP P++ P Q
Sbjct: 476 APPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP-----LQLAKPPPQAPPALATPPLQA 530
Query: 171 LPPPPTTLNG--PGASPLPLPMYRPDGLSGPPP--------PNAQYQPPPLPGQTLGAGY 220
LP PP + G P + LPM L+ PPP P Q P P TL A
Sbjct: 531 LPSPPASFPGQAPFSPSASLPM---SPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPR 587
Query: 221 PPQQANSGPQMAGAQLSYPGGFPGGPAQMAGPPQPQKKLDPDSIPSP 267
P ++G +L+ A GPP P + ++ P
Sbjct: 588 RPPTPGPDTSVSGPRLTL--------ALAPGPPPPPSRSPSSTLSGP 626
Score = 52.0 bits (123), Expect = 3e-06
Identities = 64/239 (26%), Positives = 82/239 (34%), Gaps = 36/239 (15%)
Query: 9 TPPYSQPQPGIGLSPPHYGHYGDPSHTASPTGMMKPAGPLGATATRGMLPPGPPPPGPHQ 68
+P S P + PP P A+P + P+ P T P PP PGP
Sbjct: 545 SPSASLPMSPLATPPPQA-----PPVLAAPLLQVPPSPPASPTL---QAPRRPPTPGPDT 596
Query: 69 FGQNGAHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPI---STSSVTQLGSQLS 125
+G T PGPPP P S S+ GP +SS T +L
Sbjct: 597 -SVSGPRLT---LALAPGPPP---------PPSRSPSSTLSGPDLAGHSSSATSTPEELR 643
Query: 126 AMQINSYGSGMAPPSQGPPGPLSATSLQTPPRPPQPSILQPGSQVLPPPPTTLNGPGASP 185
G A P P L+A R P P + G+ P P GPG++
Sbjct: 644 GYDSGPEGGAAASPP--PDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSAD 701
Query: 186 LPLPMYRPDGLSGPPPPNAQYQPPPLPGQT-----LGAG-----YPPQQANSGPQMAGA 234
+Y +G P P P PG + GAG P+QA G GA
Sbjct: 702 GLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGA 760
Score = 39.3 bits (90), Expect = 0.019
Identities = 58/219 (26%), Positives = 83/219 (37%), Gaps = 25/219 (11%)
Query: 48 LGATATRGMLPPGPPPPGPHQFGQNGAHAT--GHP---PQRFPGPP---PVNNV--ASSH 97
L A A R P P P P ++ A T G P P P PP P +V AS H
Sbjct: 156 LSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEH 215
Query: 98 APYQPSAQSSYPGPISTSSVTQLGSQLSAMQINSYGSGMAPPSQGPPGPLSATSLQTPPR 157
+ +PS ++ P + + + S+ ++S + ++ P++ P P
Sbjct: 216 STTEPSP-AARRRPSAGGGLQRPASR----SLSSSATPLSSPARSGPSARGTPRAPAHPS 270
Query: 158 PPQPSILQPGSQVLPPPPTTLNGPGASPLPLPMYRPDGLSGPPPPNAQYQ---PPPLPGQ 214
P+P G Q L PP T A+P P+ P P+A Q PP LP
Sbjct: 271 QPKPK----GLQALRPPQVTPPRKDAAPALGPL--SSSPLATPSPSAALQSQAPPTLPAT 324
Query: 215 TLGAGYPPQQANSGPQMAGAQLSYPGGFPGGPAQMAGPP 253
+ Q A P +A S P P+ A PP
Sbjct: 325 PHSSSLTCQLATPLP-LAPPSPSAPPSLQTLPSPPATPP 362
Score = 37.0 bits (84), Expect = 0.096
Identities = 56/240 (23%), Positives = 78/240 (32%), Gaps = 45/240 (18%)
Query: 45 AGPLGATATRGMLPPGPPPPGPHQFGQNGAHATGHPPQRFPGPPPVNNVASSHAPYQPSA 104
AGP + T P PP G A PP + P PV++ + +P
Sbjct: 77 AGPTRSAGTSSRNPASRPPASGR-----GERA---PPAKNTSPGPVSSPGRASGTTRPGP 128
Query: 105 QSSYPGPISTSSVTQLGSQLSAMQINSYGSGMAPPSQGP-PG-PLSATSLQTPPRPPQPS 162
IS G A + ++ +G + GP PG P A + ++ +
Sbjct: 129 LGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVG 188
Query: 163 ILQPGSQVLPPPPTTLNGPGAS-----------PLPLPMYRPD---GLSGPPPPNAQYQP 208
+ +P P PPT GP S P P RP GL P +
Sbjct: 189 LPRPAPSARPRPPT--EGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSA 246
Query: 209 PPLPGQTLGAGYPPQQANSGPQMAGAQLSYPGGFPGGPAQMAGP-PQPQKKLDPDSIPSP 267
PL A SGP G P PA + P P+ + L P + P
Sbjct: 247 TPL----------SSPARSGPSARGT--------PRAPAHPSQPKPKGLQALRPPQVTPP 288
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 70.9 bits (172), Expect = 6e-12
Identities = 72/262 (27%), Positives = 90/262 (34%), Gaps = 29/262 (11%)
Query: 8 ATPPYSQPQPGIGLSPPHYGHYGDPSHTASPTGMMKPAGPLGATATRGMLPPGPPPPGPH 67
+ PP Q P +PP S T T P+ PL AT PPP P
Sbjct: 307 SAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLAT-------PPPQAPP 359
Query: 68 QFGQNGAHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSY--PGPISTSSVTQLGSQLS 125
A PP PP++ +A+ +P P+A + + P S + + S
Sbjct: 360 ALALPPLQAPPSPP----ASPPLSPLATP-SPQAPNALAVHLLQAPFSPPPSPPVQAPFS 414
Query: 126 AMQINSYGSGMAPPSQGPPGPLSATSLQTPPRPPQPSILQPGSQVLPPPPTTLNGPGASP 185
PPSQ PP L+A LQ PP PP + P + P P L P
Sbjct: 415 PPASPPVSPSATPPSQAPPS-LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL 473
Query: 186 LPLPMYRPDGLSGPPPPNAQYQPPPLPGQT----------LGAGYPPQQANSGPQMAGAQ 235
P P L+ PP P PGQ PP QA P +A
Sbjct: 474 AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQA--PPVLAAPL 531
Query: 236 LSYPGGFPGGPAQMA--GPPQP 255
L P P P A PP P
Sbjct: 532 LQVPPSPPASPTLQAPRRPPTP 553
Score = 57.4 bits (137), Expect = 7e-08
Identities = 75/287 (26%), Positives = 95/287 (33%), Gaps = 46/287 (16%)
Query: 8 ATPPYSQPQPGIGLSPPHYGHYGDPSHTASPTGMMKPAGPLGATATRGMLPPGPP----- 62
ATPP SQ +G H PS SP P P PP PP
Sbjct: 320 ATPP-SQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPL 378
Query: 63 -------PPGPHQFGQNGAHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTS 115
P P+ + A PP P P + AS P PSA P S +
Sbjct: 379 SPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP--PVSPSATPPSQAPPSLA 436
Query: 116 S----VTQLGSQLSAMQINSYGSGMAPPS-QGPPGPLSATSLQTPPRPPQPSILQPGSQV 170
+ V M ++ APP PP L PP P++ P Q
Sbjct: 437 APPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP-----LQLAKPPPQAPPALATPPLQA 491
Query: 171 LPPPPTTLNG--PGASPLPLPMYRPDGLSGPPP--------PNAQYQPPPLPGQTLGAGY 220
LP PP + G P + LPM L+ PPP P Q P P TL A
Sbjct: 492 LPSPPASFPGQAPFSPSASLPM---SPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPR 548
Query: 221 PPQQANSGPQMAGAQLSYPGGFPGGPAQMAGPPQPQKKLDPDSIPSP 267
P ++G +L+ A GPP P + ++ P
Sbjct: 549 RPPTPGPDTSVSGPRLTL--------ALAPGPPPPPSRSPSSTLSGP 587
Score = 52.0 bits (123), Expect = 3e-06
Identities = 64/239 (26%), Positives = 82/239 (34%), Gaps = 36/239 (15%)
Query: 9 TPPYSQPQPGIGLSPPHYGHYGDPSHTASPTGMMKPAGPLGATATRGMLPPGPPPPGPHQ 68
+P S P + PP P A+P + P+ P T P PP PGP
Sbjct: 506 SPSASLPMSPLATPPPQA-----PPVLAAPLLQVPPSPPASPTL---QAPRRPPTPGPDT 557
Query: 69 FGQNGAHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPI---STSSVTQLGSQLS 125
+G T PGPPP P S S+ GP +SS T +L
Sbjct: 558 -SVSGPRLT---LALAPGPPP---------PPSRSPSSTLSGPDLAGHSSSATSTPEELR 604
Query: 126 AMQINSYGSGMAPPSQGPPGPLSATSLQTPPRPPQPSILQPGSQVLPPPPTTLNGPGASP 185
G A P P L+A R P P + G+ P P GPG++
Sbjct: 605 GYDSGPEGGAAASPP--PDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSAD 662
Query: 186 LPLPMYRPDGLSGPPPPNAQYQPPPLPGQT-----LGAG-----YPPQQANSGPQMAGA 234
+Y +G P P P PG + GAG P+QA G GA
Sbjct: 663 GLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGA 721
Score = 46.2 bits (108), Expect = 2e-04
Identities = 81/317 (25%), Positives = 116/317 (36%), Gaps = 45/317 (14%)
Query: 48 LGATATRGMLPPGPPPPGPHQFGQNGAHAT--GHP---PQRFPGPP---PVNNV--ASSH 97
L A A R P P P P ++ A T G P P P PP P +V AS H
Sbjct: 147 LSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEH 206
Query: 98 APYQPSAQSSYPGPISTSSVTQLGSQLSAMQINSYGSGMAPPSQGPPGPLSATSLQTPPR 157
+ +PS ++ P + + + S+ ++S + ++ P++ GP + + + P
Sbjct: 207 STTEPSP-AARRRPSAGGGLQRPASR----SLSSSATPLSSPARS--GPSARGTPRAPAH 259
Query: 158 PPQPSILQPGSQVLPPPPTTLNGPGASPL--PL---PMYRPDGLSGPPPPNAQYQPPPLP 212
P QP G Q L PP T A+P PL P+ P S PP P+A PP L
Sbjct: 260 PSQPK--PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP-SAPPSPSA---PPSLQ 313
Query: 213 GQTLGAGYPPQQANSGPQMAGAQLSYPGGFPGGPAQMAGPPQPQKKLDPDSIPSPIQVIE 272
PP QA + Q ++ P P P PQ P P+Q
Sbjct: 314 TLPSPPATPPSQATTSLGSPTLQATH-SFLPSPPLSPLATPPPQ--APPALALPPLQAPP 370
Query: 273 NDRASRGGQVYATNTRGQIPPLVTTDCMIQDQGNASPRFIRCTTYCFPCTSDMAKQAQIP 332
+ AS PPL NA + + P + + P
Sbjct: 371 SPPAS--------------PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPP 416
Query: 333 LAAVIKPFATIPSNESP 349
+ + P AT PS P
Sbjct: 417 ASPPVSPSATPPSQAPP 433
Score = 40.0 bits (92), Expect = 0.011
Identities = 63/282 (22%), Positives = 92/282 (32%), Gaps = 44/282 (15%)
Query: 5 GYVATPPYSQPQPGIGLSPPHYGHYGDPSHTASPTGMMKPAGPLGATATRGMLPPGPPPP 64
G + P P+P ++P G + G GAT +P P
Sbjct: 23 GLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGAT-----IPESAPRA 77
Query: 65 GPHQFGQNGAHATGH--PPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGS 122
GP + + A G PP + P PV++ + +P IS G
Sbjct: 78 GPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGK 137
Query: 123 QLSAMQINSYGSGMAPPSQGP-PG-PLSATSLQTPPRPPQPSILQPGSQVLPPPPTTLNG 180
A + ++ +G + GP PG P A + ++ + + +P P PPT G
Sbjct: 138 ATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPT--EG 195
Query: 181 PGAS-----------PLPLPMYRPD---GLSGPPPPNAQYQPPPLPGQTLGAGYPPQQAN 226
P S P P RP GL P + PL A
Sbjct: 196 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL----------SSPAR 245
Query: 227 SGPQMAGAQLSYPGGFPGGPAQMAGP-PQPQKKLDPDSIPSP 267
SGP G P PA + P P+ + L P + P
Sbjct: 246 SGPSARGT--------PRAPAHPSQPKPKGLQALRPPQVTPP 279
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.418
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 50,710,379
Number of Sequences: 37866
Number of extensions: 3307167
Number of successful extensions: 36309
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 309
Number of HSP's successfully gapped in prelim test: 1770
Number of HSP's that attempted gapping in prelim test: 15003
Number of HSP's gapped (non-prelim): 9976
length of query: 1032
length of database: 18,247,518
effective HSP length: 112
effective length of query: 920
effective length of database: 14,006,526
effective search space: 12886003920
effective search space used: 12886003920
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.