Guide to the Human Genome
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Search of human proteins with 166295196

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|166295196 checkpoint kinase 1 [Homo sapiens]
         (476 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|166295196 checkpoint kinase 1 [Homo sapiens]                       978   0.0  
gi|166295194 checkpoint kinase 1 [Homo sapiens]                       978   0.0  
gi|166295192 checkpoint kinase 1 [Homo sapiens]                       978   0.0  
gi|254028240 MAP/microtubule affinity-regulating kinase 2 isofor...   174   2e-43
gi|254028237 MAP/microtubule affinity-regulating kinase 2 isofor...   174   2e-43
gi|254028234 MAP/microtubule affinity-regulating kinase 2 isofor...   174   2e-43
gi|254028232 MAP/microtubule affinity-regulating kinase 2 isofor...   174   2e-43
gi|86990441 MAP/microtubule affinity-regulating kinase 2 isoform...   174   2e-43
gi|153791472 MAP/microtubule affinity-regulating kinase 1 [Homo ...   167   2e-41
gi|193083129 MAP/microtubule affinity-regulating kinase 3 isofor...   167   2e-41
gi|193083127 MAP/microtubule affinity-regulating kinase 3 isofor...   167   2e-41
gi|193083125 MAP/microtubule affinity-regulating kinase 3 isofor...   167   2e-41
gi|46852166 MAP/microtubule affinity-regulating kinase 3 isoform...   167   2e-41
gi|33636756 MAP/microtubule affinity-regulating kinase 4 [Homo s...   166   4e-41
gi|38569460 SNF1-like kinase 2 [Homo sapiens]                         164   2e-40
gi|24308326 BR serine/threonine kinase 1 [Homo sapiens]               163   4e-40
gi|116089335 BR serine/threonine kinase 2 [Homo sapiens]              160   2e-39
gi|7661974 maternal embryonic leucine zipper kinase [Homo sapiens]    160   2e-39
gi|116256471 SNF1-like kinase [Homo sapiens]                          159   5e-39
gi|94557301 protein kinase, AMP-activated, alpha 1 catalytic sub...   157   2e-38
gi|46877068 AMP-activated protein kinase alpha 2 catalytic subun...   155   1e-37
gi|38569491 serine/threonine-protein kinase QSK [Homo sapiens]        154   2e-37
gi|7657214 hormonally upregulated Neu-associated kinase [Homo sa...   151   1e-36
gi|94557299 protein kinase, AMP-activated, alpha 1 catalytic sub...   150   3e-36
gi|7662170 AMPK-related protein kinase 5 [Homo sapiens]               148   9e-36
gi|9966875 calcium/calmodulin-dependent protein kinase ID isofor...   144   1e-34
gi|23943850 calcium/calmodulin-dependent protein kinase ID isofo...   144   1e-34
gi|149589021 doublecortin-like kinase 3 [Homo sapiens]                142   7e-34
gi|54112407 protein kinase CHK2 isoform c [Homo sapiens]              140   3e-33
gi|6005850 protein kinase CHK2 isoform a [Homo sapiens]               140   3e-33

>gi|166295196 checkpoint kinase 1 [Homo sapiens]
          Length = 476

 Score =  978 bits (2529), Expect = 0.0
 Identities = 476/476 (100%), Positives = 476/476 (100%)

Query: 1   MAVPFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINK 60
           MAVPFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINK
Sbjct: 1   MAVPFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINK 60

Query: 61  MLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVY 120
           MLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVY
Sbjct: 61  MLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVY 120

Query: 121 LHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLK 180
           LHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLK
Sbjct: 121 LHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLK 180

Query: 181 RREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLA 240
           RREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLA
Sbjct: 181 RREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLA 240

Query: 241 LLHKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRVTSGGVSESPSGFSKHIQSNLDF 300
           LLHKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRVTSGGVSESPSGFSKHIQSNLDF
Sbjct: 241 LLHKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRVTSGGVSESPSGFSKHIQSNLDF 300

Query: 301 SPVNSASSEENVKYSSSQPEPRTGLSLWDTSPSYIDKLVQGISFSQPTCPDHMLLNSQLL 360
           SPVNSASSEENVKYSSSQPEPRTGLSLWDTSPSYIDKLVQGISFSQPTCPDHMLLNSQLL
Sbjct: 301 SPVNSASSEENVKYSSSQPEPRTGLSLWDTSPSYIDKLVQGISFSQPTCPDHMLLNSQLL 360

Query: 361 GTPGSSQNPWQRLVKRMTRFFTKLDADKSYQCLKETCEKLGYQWKKSCMNQVTISTTDRR 420
           GTPGSSQNPWQRLVKRMTRFFTKLDADKSYQCLKETCEKLGYQWKKSCMNQVTISTTDRR
Sbjct: 361 GTPGSSQNPWQRLVKRMTRFFTKLDADKSYQCLKETCEKLGYQWKKSCMNQVTISTTDRR 420

Query: 421 NNKLIFKVNLLEMDDKILVDFRLSKGDGLEFKRHFLKIKGKLIDIVSSQKIWLPAT 476
           NNKLIFKVNLLEMDDKILVDFRLSKGDGLEFKRHFLKIKGKLIDIVSSQKIWLPAT
Sbjct: 421 NNKLIFKVNLLEMDDKILVDFRLSKGDGLEFKRHFLKIKGKLIDIVSSQKIWLPAT 476


>gi|166295194 checkpoint kinase 1 [Homo sapiens]
          Length = 476

 Score =  978 bits (2529), Expect = 0.0
 Identities = 476/476 (100%), Positives = 476/476 (100%)

Query: 1   MAVPFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINK 60
           MAVPFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINK
Sbjct: 1   MAVPFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINK 60

Query: 61  MLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVY 120
           MLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVY
Sbjct: 61  MLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVY 120

Query: 121 LHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLK 180
           LHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLK
Sbjct: 121 LHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLK 180

Query: 181 RREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLA 240
           RREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLA
Sbjct: 181 RREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLA 240

Query: 241 LLHKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRVTSGGVSESPSGFSKHIQSNLDF 300
           LLHKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRVTSGGVSESPSGFSKHIQSNLDF
Sbjct: 241 LLHKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRVTSGGVSESPSGFSKHIQSNLDF 300

Query: 301 SPVNSASSEENVKYSSSQPEPRTGLSLWDTSPSYIDKLVQGISFSQPTCPDHMLLNSQLL 360
           SPVNSASSEENVKYSSSQPEPRTGLSLWDTSPSYIDKLVQGISFSQPTCPDHMLLNSQLL
Sbjct: 301 SPVNSASSEENVKYSSSQPEPRTGLSLWDTSPSYIDKLVQGISFSQPTCPDHMLLNSQLL 360

Query: 361 GTPGSSQNPWQRLVKRMTRFFTKLDADKSYQCLKETCEKLGYQWKKSCMNQVTISTTDRR 420
           GTPGSSQNPWQRLVKRMTRFFTKLDADKSYQCLKETCEKLGYQWKKSCMNQVTISTTDRR
Sbjct: 361 GTPGSSQNPWQRLVKRMTRFFTKLDADKSYQCLKETCEKLGYQWKKSCMNQVTISTTDRR 420

Query: 421 NNKLIFKVNLLEMDDKILVDFRLSKGDGLEFKRHFLKIKGKLIDIVSSQKIWLPAT 476
           NNKLIFKVNLLEMDDKILVDFRLSKGDGLEFKRHFLKIKGKLIDIVSSQKIWLPAT
Sbjct: 421 NNKLIFKVNLLEMDDKILVDFRLSKGDGLEFKRHFLKIKGKLIDIVSSQKIWLPAT 476


>gi|166295192 checkpoint kinase 1 [Homo sapiens]
          Length = 476

 Score =  978 bits (2529), Expect = 0.0
 Identities = 476/476 (100%), Positives = 476/476 (100%)

Query: 1   MAVPFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINK 60
           MAVPFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINK
Sbjct: 1   MAVPFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINK 60

Query: 61  MLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVY 120
           MLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVY
Sbjct: 61  MLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVY 120

Query: 121 LHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLK 180
           LHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLK
Sbjct: 121 LHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLK 180

Query: 181 RREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLA 240
           RREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLA
Sbjct: 181 RREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLA 240

Query: 241 LLHKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRVTSGGVSESPSGFSKHIQSNLDF 300
           LLHKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRVTSGGVSESPSGFSKHIQSNLDF
Sbjct: 241 LLHKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRVTSGGVSESPSGFSKHIQSNLDF 300

Query: 301 SPVNSASSEENVKYSSSQPEPRTGLSLWDTSPSYIDKLVQGISFSQPTCPDHMLLNSQLL 360
           SPVNSASSEENVKYSSSQPEPRTGLSLWDTSPSYIDKLVQGISFSQPTCPDHMLLNSQLL
Sbjct: 301 SPVNSASSEENVKYSSSQPEPRTGLSLWDTSPSYIDKLVQGISFSQPTCPDHMLLNSQLL 360

Query: 361 GTPGSSQNPWQRLVKRMTRFFTKLDADKSYQCLKETCEKLGYQWKKSCMNQVTISTTDRR 420
           GTPGSSQNPWQRLVKRMTRFFTKLDADKSYQCLKETCEKLGYQWKKSCMNQVTISTTDRR
Sbjct: 361 GTPGSSQNPWQRLVKRMTRFFTKLDADKSYQCLKETCEKLGYQWKKSCMNQVTISTTDRR 420

Query: 421 NNKLIFKVNLLEMDDKILVDFRLSKGDGLEFKRHFLKIKGKLIDIVSSQKIWLPAT 476
           NNKLIFKVNLLEMDDKILVDFRLSKGDGLEFKRHFLKIKGKLIDIVSSQKIWLPAT
Sbjct: 421 NNKLIFKVNLLEMDDKILVDFRLSKGDGLEFKRHFLKIKGKLIDIVSSQKIWLPAT 476


>gi|254028240 MAP/microtubule affinity-regulating kinase 2 isoform f
           [Homo sapiens]
          Length = 709

 Score =  174 bits (440), Expect = 2e-43
 Identities = 99/264 (37%), Positives = 154/264 (58%), Gaps = 7/264 (2%)

Query: 4   PFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCP-ENIKKEICINKML 62
           P + ++ L++T+G+G + +V+LA + +T + VAVKI+D  +      + + +E+ I K+L
Sbjct: 48  PHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVL 107

Query: 63  NHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLH 122
           NH N+VK +         YL +EY SGGE+FD +     M E +A+  F Q+++ V Y H
Sbjct: 108 NHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCH 167

Query: 123 GIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRR 182
              I HRD+K ENLLLD   N+KI+DFG +  F + N+   L+  CG+ PY APEL + +
Sbjct: 168 QKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNK---LDTFCGSPPYAAPELFQGK 224

Query: 183 EFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALL 242
           ++    VDVWS G++L  +++G LP+D    + +E  +   +  Y  P+         LL
Sbjct: 225 KYDGPEVDVWSLGVILYTLVSGSLPFD--GQNLKELRERVLRGKYRIPFYMSTDCE-NLL 281

Query: 243 HKILVENPSARITIPDIKKDRWYN 266
            K L+ NPS R T+  I KDRW N
Sbjct: 282 KKFLILNPSKRGTLEQIMKDRWMN 305


>gi|254028237 MAP/microtubule affinity-regulating kinase 2 isoform e
           [Homo sapiens]
          Length = 719

 Score =  174 bits (440), Expect = 2e-43
 Identities = 99/264 (37%), Positives = 154/264 (58%), Gaps = 7/264 (2%)

Query: 4   PFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCP-ENIKKEICINKML 62
           P + ++ L++T+G+G + +V+LA + +T + VAVKI+D  +      + + +E+ I K+L
Sbjct: 48  PHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVL 107

Query: 63  NHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLH 122
           NH N+VK +         YL +EY SGGE+FD +     M E +A+  F Q+++ V Y H
Sbjct: 108 NHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCH 167

Query: 123 GIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRR 182
              I HRD+K ENLLLD   N+KI+DFG +  F + N+   L+  CG+ PY APEL + +
Sbjct: 168 QKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNK---LDTFCGSPPYAAPELFQGK 224

Query: 183 EFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALL 242
           ++    VDVWS G++L  +++G LP+D    + +E  +   +  Y  P+         LL
Sbjct: 225 KYDGPEVDVWSLGVILYTLVSGSLPFD--GQNLKELRERVLRGKYRIPFYMSTDCE-NLL 281

Query: 243 HKILVENPSARITIPDIKKDRWYN 266
            K L+ NPS R T+  I KDRW N
Sbjct: 282 KKFLILNPSKRGTLEQIMKDRWMN 305


>gi|254028234 MAP/microtubule affinity-regulating kinase 2 isoform d
           [Homo sapiens]
          Length = 788

 Score =  174 bits (440), Expect = 2e-43
 Identities = 99/264 (37%), Positives = 154/264 (58%), Gaps = 7/264 (2%)

Query: 4   PFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCP-ENIKKEICINKML 62
           P + ++ L++T+G+G + +V+LA + +T + VAVKI+D  +      + + +E+ I K+L
Sbjct: 48  PHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVL 107

Query: 63  NHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLH 122
           NH N+VK +         YL +EY SGGE+FD +     M E +A+  F Q+++ V Y H
Sbjct: 108 NHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCH 167

Query: 123 GIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRR 182
              I HRD+K ENLLLD   N+KI+DFG +  F + N+   L+  CG+ PY APEL + +
Sbjct: 168 QKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNK---LDTFCGSPPYAAPELFQGK 224

Query: 183 EFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALL 242
           ++    VDVWS G++L  +++G LP+D    + +E  +   +  Y  P+         LL
Sbjct: 225 KYDGPEVDVWSLGVILYTLVSGSLPFD--GQNLKELRERVLRGKYRIPFYMSTDCE-NLL 281

Query: 243 HKILVENPSARITIPDIKKDRWYN 266
            K L+ NPS R T+  I KDRW N
Sbjct: 282 KKFLILNPSKRGTLEQIMKDRWMN 305


>gi|254028232 MAP/microtubule affinity-regulating kinase 2 isoform c
           [Homo sapiens]
          Length = 724

 Score =  174 bits (440), Expect = 2e-43
 Identities = 99/264 (37%), Positives = 154/264 (58%), Gaps = 7/264 (2%)

Query: 4   PFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCP-ENIKKEICINKML 62
           P + ++ L++T+G+G + +V+LA + +T + VAVKI+D  +      + + +E+ I K+L
Sbjct: 48  PHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVL 107

Query: 63  NHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLH 122
           NH N+VK +         YL +EY SGGE+FD +     M E +A+  F Q+++ V Y H
Sbjct: 108 NHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCH 167

Query: 123 GIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRR 182
              I HRD+K ENLLLD   N+KI+DFG +  F + N+   L+  CG+ PY APEL + +
Sbjct: 168 QKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNK---LDTFCGSPPYAAPELFQGK 224

Query: 183 EFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALL 242
           ++    VDVWS G++L  +++G LP+D    + +E  +   +  Y  P+         LL
Sbjct: 225 KYDGPEVDVWSLGVILYTLVSGSLPFD--GQNLKELRERVLRGKYRIPFYMSTDCE-NLL 281

Query: 243 HKILVENPSARITIPDIKKDRWYN 266
            K L+ NPS R T+  I KDRW N
Sbjct: 282 KKFLILNPSKRGTLEQIMKDRWMN 305


>gi|86990441 MAP/microtubule affinity-regulating kinase 2 isoform a
           [Homo sapiens]
          Length = 745

 Score =  174 bits (440), Expect = 2e-43
 Identities = 99/264 (37%), Positives = 154/264 (58%), Gaps = 7/264 (2%)

Query: 4   PFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCP-ENIKKEICINKML 62
           P + ++ L++T+G+G + +V+LA + +T + VAVKI+D  +      + + +E+ I K+L
Sbjct: 15  PHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVL 74

Query: 63  NHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLH 122
           NH N+VK +         YL +EY SGGE+FD +     M E +A+  F Q+++ V Y H
Sbjct: 75  NHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCH 134

Query: 123 GIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRR 182
              I HRD+K ENLLLD   N+KI+DFG +  F + N+   L+  CG+ PY APEL + +
Sbjct: 135 QKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNK---LDTFCGSPPYAAPELFQGK 191

Query: 183 EFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALL 242
           ++    VDVWS G++L  +++G LP+D    + +E  +   +  Y  P+         LL
Sbjct: 192 KYDGPEVDVWSLGVILYTLVSGSLPFD--GQNLKELRERVLRGKYRIPFYMSTDCE-NLL 248

Query: 243 HKILVENPSARITIPDIKKDRWYN 266
            K L+ NPS R T+  I KDRW N
Sbjct: 249 KKFLILNPSKRGTLEQIMKDRWMN 272


>gi|153791472 MAP/microtubule affinity-regulating kinase 1 [Homo
           sapiens]
          Length = 795

 Score =  167 bits (423), Expect = 2e-41
 Identities = 98/264 (37%), Positives = 151/264 (57%), Gaps = 7/264 (2%)

Query: 4   PFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCP-ENIKKEICINKML 62
           P + ++ L +T+G+G + +V+LA + +T   VAVKI+D  +      + + +E+ I K+L
Sbjct: 55  PHIGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKIL 114

Query: 63  NHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLH 122
           NH N+VK +         YL +EY SGGE+FD +     M E +A+  F Q+++ V Y H
Sbjct: 115 NHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCH 174

Query: 123 GIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRR 182
              I HRD+K ENLLLD   N+KI+DFG +  F   N+   L+  CG+ PY APEL + +
Sbjct: 175 QKYIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNK---LDTFCGSPPYAAPELFQGK 231

Query: 183 EFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALL 242
           ++    VDVWS G++L  +++G LP+D    + +E  +   +  Y  P+         LL
Sbjct: 232 KYDGPEVDVWSLGVILYTLVSGSLPFD--GQNLKELRERVLRGKYRIPFYMSTDCE-NLL 288

Query: 243 HKILVENPSARITIPDIKKDRWYN 266
            K+LV NP  R ++  I KDRW N
Sbjct: 289 KKLLVLNPIKRGSLEQIMKDRWMN 312


>gi|193083129 MAP/microtubule affinity-regulating kinase 3 isoform d
           [Homo sapiens]
          Length = 713

 Score =  167 bits (423), Expect = 2e-41
 Identities = 98/276 (35%), Positives = 155/276 (56%), Gaps = 7/276 (2%)

Query: 4   PFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCP-ENIKKEICINKML 62
           P + ++ L++T+G+G + +V+LA + +T   VA+KI+D  +      + + +E+ I K+L
Sbjct: 51  PHIGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKIL 110

Query: 63  NHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLH 122
           NH N+VK +         YL +EY SGGE+FD +     M E +A+  F Q+++ V Y H
Sbjct: 111 NHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCH 170

Query: 123 GIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRR 182
              I HRD+K ENLLLD   N+KI+DFG +  F    +   L+  CG+ PY APEL + +
Sbjct: 171 QKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGK---LDTFCGSPPYAAPELFQGK 227

Query: 183 EFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALL 242
           ++    VDVWS G++L  +++G LP+D    + +E  +   +  Y  P+         LL
Sbjct: 228 KYDGPEVDVWSLGVILYTLVSGSLPFD--GQNLKELRERVLRGKYRIPFYMSTDCE-NLL 284

Query: 243 HKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRV 278
            + LV NP  R T+  I KDRW N   ++   +P V
Sbjct: 285 KRFLVLNPIKRGTLEQIMKDRWINAGHEEDELKPFV 320


>gi|193083127 MAP/microtubule affinity-regulating kinase 3 isoform b
           [Homo sapiens]
          Length = 744

 Score =  167 bits (423), Expect = 2e-41
 Identities = 98/276 (35%), Positives = 155/276 (56%), Gaps = 7/276 (2%)

Query: 4   PFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCP-ENIKKEICINKML 62
           P + ++ L++T+G+G + +V+LA + +T   VA+KI+D  +      + + +E+ I K+L
Sbjct: 51  PHIGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKIL 110

Query: 63  NHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLH 122
           NH N+VK +         YL +EY SGGE+FD +     M E +A+  F Q+++ V Y H
Sbjct: 111 NHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCH 170

Query: 123 GIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRR 182
              I HRD+K ENLLLD   N+KI+DFG +  F    +   L+  CG+ PY APEL + +
Sbjct: 171 QKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGK---LDTFCGSPPYAAPELFQGK 227

Query: 183 EFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALL 242
           ++    VDVWS G++L  +++G LP+D    + +E  +   +  Y  P+         LL
Sbjct: 228 KYDGPEVDVWSLGVILYTLVSGSLPFD--GQNLKELRERVLRGKYRIPFYMSTDCE-NLL 284

Query: 243 HKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRV 278
            + LV NP  R T+  I KDRW N   ++   +P V
Sbjct: 285 KRFLVLNPIKRGTLEQIMKDRWINAGHEEDELKPFV 320


>gi|193083125 MAP/microtubule affinity-regulating kinase 3 isoform a
           [Homo sapiens]
          Length = 753

 Score =  167 bits (423), Expect = 2e-41
 Identities = 98/276 (35%), Positives = 155/276 (56%), Gaps = 7/276 (2%)

Query: 4   PFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCP-ENIKKEICINKML 62
           P + ++ L++T+G+G + +V+LA + +T   VA+KI+D  +      + + +E+ I K+L
Sbjct: 51  PHIGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKIL 110

Query: 63  NHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLH 122
           NH N+VK +         YL +EY SGGE+FD +     M E +A+  F Q+++ V Y H
Sbjct: 111 NHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCH 170

Query: 123 GIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRR 182
              I HRD+K ENLLLD   N+KI+DFG +  F    +   L+  CG+ PY APEL + +
Sbjct: 171 QKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGK---LDTFCGSPPYAAPELFQGK 227

Query: 183 EFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALL 242
           ++    VDVWS G++L  +++G LP+D    + +E  +   +  Y  P+         LL
Sbjct: 228 KYDGPEVDVWSLGVILYTLVSGSLPFD--GQNLKELRERVLRGKYRIPFYMSTDCE-NLL 284

Query: 243 HKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRV 278
            + LV NP  R T+  I KDRW N   ++   +P V
Sbjct: 285 KRFLVLNPIKRGTLEQIMKDRWINAGHEEDELKPFV 320


>gi|46852166 MAP/microtubule affinity-regulating kinase 3 isoform c
           [Homo sapiens]
          Length = 729

 Score =  167 bits (423), Expect = 2e-41
 Identities = 98/276 (35%), Positives = 155/276 (56%), Gaps = 7/276 (2%)

Query: 4   PFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCP-ENIKKEICINKML 62
           P + ++ L++T+G+G + +V+LA + +T   VA+KI+D  +      + + +E+ I K+L
Sbjct: 51  PHIGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKIL 110

Query: 63  NHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLH 122
           NH N+VK +         YL +EY SGGE+FD +     M E +A+  F Q+++ V Y H
Sbjct: 111 NHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCH 170

Query: 123 GIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRR 182
              I HRD+K ENLLLD   N+KI+DFG +  F    +   L+  CG+ PY APEL + +
Sbjct: 171 QKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGK---LDTFCGSPPYAAPELFQGK 227

Query: 183 EFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALL 242
           ++    VDVWS G++L  +++G LP+D    + +E  +   +  Y  P+         LL
Sbjct: 228 KYDGPEVDVWSLGVILYTLVSGSLPFD--GQNLKELRERVLRGKYRIPFYMSTDCE-NLL 284

Query: 243 HKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRV 278
            + LV NP  R T+  I KDRW N   ++   +P V
Sbjct: 285 KRFLVLNPIKRGTLEQIMKDRWINAGHEEDELKPFV 320


>gi|33636756 MAP/microtubule affinity-regulating kinase 4 [Homo
           sapiens]
          Length = 688

 Score =  166 bits (420), Expect = 4e-41
 Identities = 95/266 (35%), Positives = 153/266 (57%), Gaps = 11/266 (4%)

Query: 4   PFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKK---EICINK 60
           P V ++ L++T+G+G + +V+LA + +T   VA+KI+D  +    P +++K   E+ I K
Sbjct: 54  PHVGNYRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLN--PSSLQKLFREVRIMK 111

Query: 61  MLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVY 120
            LNH N+VK +         YL +EY S GE+FD +     M E +A+  F Q+++ V Y
Sbjct: 112 GLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHY 171

Query: 121 LHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLK 180
            H   I HRD+K ENLLLD   N+KI+DFG +  F   ++   L+  CG+ PY APEL +
Sbjct: 172 CHQKNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSK---LDTFCGSPPYAAPELFQ 228

Query: 181 RREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLA 240
            +++    VD+WS G++L  +++G LP+D    + +E  +   +  Y  P+        +
Sbjct: 229 GKKYDGPEVDIWSLGVILYTLVSGSLPFD--GHNLKELRERVLRGKYRVPFYMSTDCE-S 285

Query: 241 LLHKILVENPSARITIPDIKKDRWYN 266
           +L + LV NP+ R T+  I KD+W N
Sbjct: 286 ILRRFLVLNPAKRCTLEQIMKDKWIN 311


>gi|38569460 SNF1-like kinase 2 [Homo sapiens]
          Length = 926

 Score =  164 bits (415), Expect = 2e-40
 Identities = 111/378 (29%), Positives = 195/378 (51%), Gaps = 22/378 (5%)

Query: 9   WDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKR--AVDCPENIKKEICINKMLNHEN 66
           +D+  TLG+G +  V+L  +R+T+  VA+KI+D  +  AV+  E I +E+ I KML+H +
Sbjct: 20  YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNL-EKIYREVQIMKMLDHPH 78

Query: 67  VVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGI 126
           ++K Y      ++ YL  EY   GE+FD +     + E +A+R F Q+++ V Y HG  I
Sbjct: 79  IIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKI 138

Query: 127 THRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRREFHA 186
            HRD+K ENLLLD   N+KI+DFG    F+      LL   CG+ PY APE+ + +++  
Sbjct: 139 VHRDLKAENLLLDNNMNIKIADFGFGNFFKSG---ELLATWCGSPPYAAPEVFEGQQYEG 195

Query: 187 EPVDVWSCGIVLTAMLAGELPWDQPSDSC--QEYSDWKEKKTYLNPWKKIDSAPLALLHK 244
             +D+WS G+VL  ++ G LP+D P+     Q   + + +  Y      +      L+ +
Sbjct: 196 PQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYF-----MSEDCEHLIRR 250

Query: 245 ILVENPSARITIPDIKKDRWYNKPLKKGAKRPRVTSGGVSESPS--GFSKHIQSNLDFSP 302
           +LV +PS R+TI  IK+ +W    ++   +RP +        PS   F++ +   +    
Sbjct: 251 MLVLDPSKRLTIAQIKEHKW--MLIEVPVQRPVLYPQEQENEPSIGEFNEQVLRLMHSLG 308

Query: 303 VNSASSEENVKYSSSQPEPRTGLSLWDTSPSY-----IDKLVQGISFSQPTCPDHMLLNS 357
           ++   + E+++  S          L +   S+     +++ + G      T  +  +  +
Sbjct: 309 IDQQKTIESLQNKSYNHFAAIYFLLVERLKSHRSSFPVEQRLDGRQRRPSTIAEQTVAKA 368

Query: 358 QLLGTPGSSQNPWQRLVK 375
           Q +G P +  +P  RL++
Sbjct: 369 QTVGLPVTMHSPNMRLLR 386


>gi|24308326 BR serine/threonine kinase 1 [Homo sapiens]
          Length = 778

 Score =  163 bits (412), Expect = 4e-40
 Identities = 90/262 (34%), Positives = 155/262 (59%), Gaps = 7/262 (2%)

Query: 5   FVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCP-ENIKKEICINKMLN 63
           +V  + L +TLG+G  G V+L V+ +T + VA+KIV+ ++  +     +++EI I K++ 
Sbjct: 30  YVGPYRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSESVLMKVEREIAILKLIE 89

Query: 64  HENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHG 123
           H +V+K +         YL LE+ SGGELFD +     +   +A++FF Q+++ + + H 
Sbjct: 90  HPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHS 149

Query: 124 IGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRRE 183
             I HRD+KPENLLLDE++N++I+DFG+A++      + LL   CG+  Y  PE++K  +
Sbjct: 150 YSICHRDLKPENLLLDEKNNIRIADFGMASL---QVGDSLLETSCGSPHYACPEVIKGEK 206

Query: 184 FHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLH 243
           +     D+WSCG++L A+L G LP+D   D+ ++  + K K+   +    I     +LL 
Sbjct: 207 YDGRRADMWSCGVILFALLVGALPFD--DDNLRQLLE-KVKRGVFHMPHFIPPDCQSLLR 263

Query: 244 KILVENPSARITIPDIKKDRWY 265
            ++   P  R+++  I+K  WY
Sbjct: 264 GMIEVEPEKRLSLEQIQKHPWY 285


>gi|116089335 BR serine/threonine kinase 2 [Homo sapiens]
          Length = 668

 Score =  160 bits (406), Expect = 2e-39
 Identities = 91/262 (34%), Positives = 156/262 (59%), Gaps = 7/262 (2%)

Query: 5   FVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCP-ENIKKEICINKMLN 63
           +V  + L +TLG+G  G V+L V+ VT + VA+KIV+ ++  +     +++EI I K++ 
Sbjct: 15  YVGPYRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSESVLMKVEREIAILKLIE 74

Query: 64  HENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHG 123
           H +V+K +         YL LE+ SGGELFD +     +   +A++FF Q+++ + + H 
Sbjct: 75  HPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHS 134

Query: 124 IGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRRE 183
             I HRD+KPENLLLDE++N++I+DFG+A++      + LL   CG+  Y  PE+++  +
Sbjct: 135 HSICHRDLKPENLLLDEKNNIRIADFGMASL---QVGDSLLETSCGSPHYACPEVIRGEK 191

Query: 184 FHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLH 243
           +     DVWSCG++L A+L G LP+D   D+ ++  + K K+   +    I     +LL 
Sbjct: 192 YDGRKADVWSCGVILFALLVGALPFD--DDNLRQLLE-KVKRGVFHMPHFIPPDCQSLLR 248

Query: 244 KILVENPSARITIPDIKKDRWY 265
            ++  + + R+T+  I+K  WY
Sbjct: 249 GMIEVDAARRLTLEHIQKHIWY 270


>gi|7661974 maternal embryonic leucine zipper kinase [Homo sapiens]
          Length = 651

 Score =  160 bits (406), Expect = 2e-39
 Identities = 94/272 (34%), Positives = 147/272 (54%), Gaps = 8/272 (2%)

Query: 9   WDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINKMLNHENVV 68
           ++L +T+G G + +V+LA + +T E VA+KI+D          IK EI   K L H+++ 
Sbjct: 11  YELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSDLPRIKTEIEALKNLRHQHIC 70

Query: 69  KFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITH 128
           + Y      N  ++ LEYC GGELFD I     + E + +  F Q+++ V Y+H  G  H
Sbjct: 71  QLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAH 130

Query: 129 RDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRREFHAEP 188
           RD+KPENLL DE   LK+ DFGL    +  N++  L   CG+L Y APEL++ + +    
Sbjct: 131 RDLKPENLLFDEYHKLKLIDFGLCAKPK-GNKDYHLQTCCGSLAYAAPELIQGKSYLGSE 189

Query: 189 VDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKILVE 248
            DVWS GI+L  ++ G LP+D   +    Y      K  +  W  +  + + LL ++L  
Sbjct: 190 ADVWSMGILLYVLMCGFLPFDD-DNVMALYKKIMRGKYDVPKW--LSPSSILLLQQMLQV 246

Query: 249 NPSARITIPDIKKDRW----YNKPLKKGAKRP 276
           +P  RI++ ++    W    YN P++  +K P
Sbjct: 247 DPKKRISMKNLLNHPWIMQDYNYPVEWQSKNP 278


>gi|116256471 SNF1-like kinase [Homo sapiens]
          Length = 783

 Score =  159 bits (402), Expect = 5e-39
 Identities = 93/312 (29%), Positives = 170/312 (54%), Gaps = 12/312 (3%)

Query: 9   WDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCP-ENIKKEICINKMLNHENV 67
           +D+ +TLG+G +  V+LA +RVT+  VA+KI+D  R      E I +E+ + K+LNH ++
Sbjct: 27  YDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSNLEKIYREVQLMKLLNHPHI 86

Query: 68  VKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGIT 127
           +K Y      ++ Y+  E+   GE+FD +  +  + E +A++ F Q+++ V Y H   I 
Sbjct: 87  IKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCHDHHIV 146

Query: 128 HRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRREFHAE 187
           HRD+K ENLLLD   ++K++DFG    ++       L+  CG+ PY APE+ + +E+   
Sbjct: 147 HRDLKTENLLLDGNMDIKLADFGFGNFYKSGEP---LSTWCGSPPYAAPEVFEGKEYEGP 203

Query: 188 PVDVWSCGIVLTAMLAGELPWDQPS--DSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKI 245
            +D+WS G+VL  ++ G LP+D P+     Q   + + +  +      +     +L+ ++
Sbjct: 204 QLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFF-----MSQDCESLIRRM 258

Query: 246 LVENPSARITIPDIKKDRWYN-KPLKKGAKRPRVTSGGVSESPSGFSKHIQSNLDFSPVN 304
           LV +P+ RITI  I++ RW   +P   G   P  ++   + +   + +     +    V+
Sbjct: 259 LVVDPARRITIAQIRQHRWMRAEPCLPGPACPAFSAHSYTSNLGDYDEQALGIMQTLGVD 318

Query: 305 SASSEENVKYSS 316
              + E+++ SS
Sbjct: 319 RQRTVESLQNSS 330


>gi|94557301 protein kinase, AMP-activated, alpha 1 catalytic
           subunit isoform 1 [Homo sapiens]
          Length = 559

 Score =  157 bits (398), Expect = 2e-38
 Identities = 94/266 (35%), Positives = 150/266 (56%), Gaps = 14/266 (5%)

Query: 11  LVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMK--RAVDCPENIKKEICINKMLNHENVV 68
           L  TLG G +G+V++  + +T   VAVKI++ +  R++D    I++EI   K+  H +++
Sbjct: 29  LGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHII 88

Query: 69  KFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITH 128
           K Y      +  ++ +EY SGGELFD I  +  + E +++R F Q+++GV Y H   + H
Sbjct: 89  KLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVH 148

Query: 129 RDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRREFHAEP 188
           RD+KPEN+LLD   N KI+DFGL+ +    +    L   CG+  Y APE++  R +    
Sbjct: 149 RDLKPENVLLDAHMNAKIADFGLSNMM---SDGEFLRTSCGSPNYAAPEVISGRLYAGPE 205

Query: 189 VDVWSCGIVLTAMLAGELPWDQ---PSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKI 245
           VD+WS G++L A+L G LP+D    P+   +          YLNP      + ++LL  +
Sbjct: 206 VDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNP------SVISLLKHM 259

Query: 246 LVENPSARITIPDIKKDRWYNKPLKK 271
           L  +P  R TI DI++  W+ + L K
Sbjct: 260 LQVDPMKRATIKDIREHEWFKQDLPK 285


>gi|46877068 AMP-activated protein kinase alpha 2 catalytic subunit
           [Homo sapiens]
          Length = 552

 Score =  155 bits (391), Expect = 1e-37
 Identities = 95/265 (35%), Positives = 146/265 (55%), Gaps = 16/265 (6%)

Query: 11  LVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMK--RAVDCPENIKKEICINKMLNHENVV 68
           L  TLG G +G+V++  +++T   VAVKI++ +  R++D    IK+EI   K+  H +++
Sbjct: 18  LGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHII 77

Query: 69  KFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITH 128
           K Y         ++ +EY SGGELFD I     + E +A+R F Q+++ V Y H   + H
Sbjct: 78  KLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMVVH 137

Query: 129 RDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRREFHAEP 188
           RD+KPEN+LLD   N KI+DFGL+ +    +    L   CG+  Y APE++  R +    
Sbjct: 138 RDLKPENVLLDAHMNAKIADFGLSNMM---SDGEFLRTSCGSPNYAAPEVISGRLYAGPE 194

Query: 189 VDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKK----TYLNPWKKIDSAPLALLHK 244
           VD+WSCG++L A+L G LP+D       E+     KK     +  P     S    L+H 
Sbjct: 195 VDIWSCGVILYALLCGTLPFD------DEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHM 248

Query: 245 ILVENPSARITIPDIKKDRWYNKPL 269
           + V+ P  R TI DI++  W+ + L
Sbjct: 249 LQVD-PLKRATIKDIREHEWFKQDL 272


>gi|38569491 serine/threonine-protein kinase QSK [Homo sapiens]
          Length = 1263

 Score =  154 bits (389), Expect = 2e-37
 Identities = 93/259 (35%), Positives = 146/259 (56%), Gaps = 11/259 (4%)

Query: 9   WDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKK---EICINKMLNHE 65
           +++ +T+G+G +  V+ A + VT+  VA+KI+D K  +D  EN+KK   E+ I KML H 
Sbjct: 8   YEIDRTIGKGNFAVVKRATHLVTKAKVAIKIID-KTQLD-EENLKKIFREVQIMKMLCHP 65

Query: 66  NVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIG 125
           ++++ Y       + YL  EY SGGE+FD +     M E +A+R F Q++  V + H   
Sbjct: 66  HIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRN 125

Query: 126 ITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRREFH 185
           I HRD+K ENLLLD   N+KI+DFG + +F      +LL   CG+ PY APEL + +E+ 
Sbjct: 126 IVHRDLKAENLLLDANLNIKIADFGFSNLF---TPGQLLKTWCGSPPYAAPELFEGKEYD 182

Query: 186 AEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKI 245
              VD+WS G+VL  ++ G LP+D    + Q          +  P+         + H +
Sbjct: 183 GPKVDIWSLGVVLYVLVCGALPFD--GSTLQNLRARVLSGKFRIPFFMSTECEHLIRH-M 239

Query: 246 LVENPSARITIPDIKKDRW 264
           LV +P+ R+++  I K +W
Sbjct: 240 LVLDPNKRLSMEQICKHKW 258


>gi|7657214 hormonally upregulated Neu-associated kinase [Homo
           sapiens]
          Length = 714

 Score =  151 bits (382), Expect = 1e-36
 Identities = 88/258 (34%), Positives = 143/258 (55%), Gaps = 8/258 (3%)

Query: 15  LGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVD---CPENIKKEICINKMLNHENVVKFY 71
           LGEG++ +V+  ++ +T E VA+K++D KRA       +N+++E  I +M+ H N+ +  
Sbjct: 68  LGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQLL 127

Query: 72  GHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDI 131
                 N  YL +E C GG L  +I     + E +A+R+  QL++ V +LH  G+ HRD+
Sbjct: 128 DILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISAVEHLHRAGVVHRDL 187

Query: 132 KPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDV 191
           K ENLLLDE +N+K+ DFGL+            +  CG+  Y APELL R+++    +DV
Sbjct: 188 KIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLARKKY-GPKIDV 246

Query: 192 WSCGIVLTAMLAGELPWD-QPSDSCQEYSDWKEKKTYLNPW-KKIDSAPLALLHKILVEN 249
           WS G+ + AML G LP+  +P      Y    +K+  +NP   ++ +  ++ L  +L  +
Sbjct: 247 WSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKE--MNPLPTQLSTGAISFLRSLLEPD 304

Query: 250 PSARITIPDIKKDRWYNK 267
           P  R  I     +RW N+
Sbjct: 305 PVKRPNIQQALANRWLNE 322


>gi|94557299 protein kinase, AMP-activated, alpha 1 catalytic
           subunit isoform 2 [Homo sapiens]
          Length = 574

 Score =  150 bits (378), Expect = 3e-36
 Identities = 95/281 (33%), Positives = 152/281 (54%), Gaps = 29/281 (10%)

Query: 11  LVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMK--RAVDCPENIKKEICINKMLNHENVV 68
           L  TLG G +G+V++  + +T   VAVKI++ +  R++D    I++EI   K+  H +++
Sbjct: 29  LGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHII 88

Query: 69  KFYGHRREGNIQYLFLEYCSGGELFDRI-----EPDIG----------MPEPDAQRFFHQ 113
           K Y      +  ++ +EY SGGELFD I     + D+           + E +++R F Q
Sbjct: 89  KLYQVISTPSDIFMVMEYVSGGELFDYICKNGRKSDVPGVVKTGSTKELDEKESRRLFQQ 148

Query: 114 LMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPY 173
           +++GV Y H   + HRD+KPEN+LLD   N KI+DFGL+ +    +    L   CG+  Y
Sbjct: 149 ILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMM---SDGEFLRTSCGSPNY 205

Query: 174 VAPELLKRREFHAEPVDVWSCGIVLTAMLAGELPWDQ---PSDSCQEYSDWKEKKTYLNP 230
            APE++  R +    VD+WS G++L A+L G LP+D    P+   +          YLNP
Sbjct: 206 AAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNP 265

Query: 231 WKKIDSAPLALLHKILVENPSARITIPDIKKDRWYNKPLKK 271
                 + ++LL  +L  +P  R TI DI++  W+ + L K
Sbjct: 266 ------SVISLLKHMLQVDPMKRATIKDIREHEWFKQDLPK 300


>gi|7662170 AMPK-related protein kinase 5 [Homo sapiens]
          Length = 661

 Score =  148 bits (374), Expect = 9e-36
 Identities = 84/262 (32%), Positives = 145/262 (55%), Gaps = 13/262 (4%)

Query: 9   WDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPE--NIKKEICINKMLNHEN 66
           ++L +TLG+G YG+V+ A  R +   VA+K +   +  D  +  +I++EI I   LNH +
Sbjct: 55  YELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNHPH 114

Query: 67  VVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGI 126
           ++  Y      +   + +EY S GEL+D I     + E + + FF Q+++ V Y H  G+
Sbjct: 115 IISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKNGV 174

Query: 127 THRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRREFHA 186
            HRD+K EN+LLD+  N+KI+DFGL+ +++   +++ L   CG+  Y +PE++  R +  
Sbjct: 175 VHRDLKLENILLDDNCNIKIADFGLSNLYQ---KDKFLQTFCGSPLYASPEIVNGRPYRG 231

Query: 187 EPVDVWSCGIVLTAMLAGELPWD--QPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHK 244
             VD W+ G++L  ++ G +P+D     +  ++ S  +    Y  P +  D+    L+  
Sbjct: 232 PEVDSWALGVLLYTLVYGTMPFDGFDHKNLIRQISSGE----YREPTQPSDAR--GLIRW 285

Query: 245 ILVENPSARITIPDIKKDRWYN 266
           +L+ NP  R TI DI    W N
Sbjct: 286 MLMVNPDRRATIEDIANHWWVN 307


>gi|9966875 calcium/calmodulin-dependent protein kinase ID isoform 1
           [Homo sapiens]
          Length = 357

 Score =  144 bits (364), Expect = 1e-34
 Identities = 87/260 (33%), Positives = 135/260 (51%), Gaps = 8/260 (3%)

Query: 9   WDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINKMLNHENVV 68
           ++  +TLG GA+ EV LA  + T +  AVK +  K       +I+ EI + + + HEN+V
Sbjct: 23  FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKIKHENIV 82

Query: 69  KFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITH 128
                    N  YL ++  SGGELFDRI       E DA     Q++  V YLH +GI H
Sbjct: 83  ALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVH 142

Query: 129 RDIKPENLLL---DERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRREFH 185
           RD+KPENLL    DE   + ISDFGL+   +   +  +++  CGT  YVAPE+L ++ + 
Sbjct: 143 RDLKPENLLYYSQDEESKIMISDFGLS---KMEGKGDVMSTACGTPGYVAPEVLAQKPY- 198

Query: 186 AEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNP-WKKIDSAPLALLHK 244
           ++ VD WS G++   +L G  P+   +DS       K +  + +P W  I  +    +  
Sbjct: 199 SKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRN 258

Query: 245 ILVENPSARITIPDIKKDRW 264
           ++ ++P+ R T     +  W
Sbjct: 259 LMEKDPNKRYTCEQAARHPW 278


>gi|23943850 calcium/calmodulin-dependent protein kinase ID isoform
           2 [Homo sapiens]
          Length = 385

 Score =  144 bits (364), Expect = 1e-34
 Identities = 87/260 (33%), Positives = 135/260 (51%), Gaps = 8/260 (3%)

Query: 9   WDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINKMLNHENVV 68
           ++  +TLG GA+ EV LA  + T +  AVK +  K       +I+ EI + + + HEN+V
Sbjct: 23  FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKIKHENIV 82

Query: 69  KFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITH 128
                    N  YL ++  SGGELFDRI       E DA     Q++  V YLH +GI H
Sbjct: 83  ALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVH 142

Query: 129 RDIKPENLLL---DERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRREFH 185
           RD+KPENLL    DE   + ISDFGL+   +   +  +++  CGT  YVAPE+L ++ + 
Sbjct: 143 RDLKPENLLYYSQDEESKIMISDFGLS---KMEGKGDVMSTACGTPGYVAPEVLAQKPY- 198

Query: 186 AEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNP-WKKIDSAPLALLHK 244
           ++ VD WS G++   +L G  P+   +DS       K +  + +P W  I  +    +  
Sbjct: 199 SKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRN 258

Query: 245 ILVENPSARITIPDIKKDRW 264
           ++ ++P+ R T     +  W
Sbjct: 259 LMEKDPNKRYTCEQAARHPW 278


>gi|149589021 doublecortin-like kinase 3 [Homo sapiens]
          Length = 648

 Score =  142 bits (358), Expect = 7e-34
 Identities = 89/259 (34%), Positives = 135/259 (52%), Gaps = 13/259 (5%)

Query: 13  QTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINKMLNHENVVKFYG 72
           + +G+G +  V+   +R T +A A+KI+D  R     + +  EI I + L+H N+VK + 
Sbjct: 360 RVIGDGNFAVVKECRHRETRQAYAMKIIDKSRLKGKEDMVDSEILIIQSLSHPNIVKLHE 419

Query: 73  HRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIK 132
                   YL LEY  GG+LFD I   +  PEPDA      L   +V++H   I HRD+K
Sbjct: 420 VYETDMEIYLILEYVQGGDLFDAIIESVKFPEPDAALMIMDLCKALVHMHDKSIVHRDLK 479

Query: 133 PENLLL----DERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRREFHAEP 188
           PENLL+    D+   LK++DFGLA      +  R +  +CGT  YVAPE+L  + +  E 
Sbjct: 480 PENLLVQRNEDKSTTLKLADFGLA-----KHVVRPIFTVCGTPTYVAPEILSEKGYGLE- 533

Query: 189 VDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKE--KKTYLNP-WKKIDSAPLALLHKI 245
           VD+W+ G++L  +L G  P+  P     E  +  +     +L P W  I  A   L+ ++
Sbjct: 534 VDMWAAGVILYILLCGFPPFRSPERDQDELFNIIQLGHFEFLPPYWDNISDAAKDLVSRL 593

Query: 246 LVENPSARITIPDIKKDRW 264
           LV +P  R T   + +  W
Sbjct: 594 LVVDPKKRYTAHQVLQHPW 612


>gi|54112407 protein kinase CHK2 isoform c [Homo sapiens]
          Length = 586

 Score =  140 bits (352), Expect = 3e-33
 Identities = 90/272 (33%), Positives = 140/272 (51%), Gaps = 18/272 (6%)

Query: 7   EDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMK-------RAVDCPENIKKEICIN 59
           +++ + +TLG GA GEV+LA  R T + VA+KI+  +       R  D   N++ EI I 
Sbjct: 261 DEYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEIL 320

Query: 60  KMLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVV 119
           K LNH  ++K      +    Y+ LE   GGELFD++  +  + E   + +F+Q++  V 
Sbjct: 321 KKLNHPCIIKIKNFF-DAEDYYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQ 379

Query: 120 YLHGIGITHRDIKPENLLLDERDN---LKISDFGLATVFRYNNRERLLNKMCGTLPYVAP 176
           YLH  GI HRD+KPEN+LL  ++    +KI+DFG + +        L+  +CGT  Y+AP
Sbjct: 380 YLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKIL---GETSLMRTLCGTPTYLAP 436

Query: 177 ELLKR--REFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNP--WK 232
           E+L       +   VD WS G++L   L+G  P+ +              K    P  W 
Sbjct: 437 EVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWA 496

Query: 233 KIDSAPLALLHKILVENPSARITIPDIKKDRW 264
           ++    L L+ K+LV +P AR T  +  +  W
Sbjct: 497 EVSEKALDLVKKLLVVDPKARFTTEEALRHPW 528


>gi|6005850 protein kinase CHK2 isoform a [Homo sapiens]
          Length = 543

 Score =  140 bits (352), Expect = 3e-33
 Identities = 90/272 (33%), Positives = 140/272 (51%), Gaps = 18/272 (6%)

Query: 7   EDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMK-------RAVDCPENIKKEICIN 59
           +++ + +TLG GA GEV+LA  R T + VA+KI+  +       R  D   N++ EI I 
Sbjct: 218 DEYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEIL 277

Query: 60  KMLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVV 119
           K LNH  ++K      +    Y+ LE   GGELFD++  +  + E   + +F+Q++  V 
Sbjct: 278 KKLNHPCIIKIKNFF-DAEDYYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQ 336

Query: 120 YLHGIGITHRDIKPENLLLDERDN---LKISDFGLATVFRYNNRERLLNKMCGTLPYVAP 176
           YLH  GI HRD+KPEN+LL  ++    +KI+DFG + +        L+  +CGT  Y+AP
Sbjct: 337 YLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKIL---GETSLMRTLCGTPTYLAP 393

Query: 177 ELLKR--REFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNP--WK 232
           E+L       +   VD WS G++L   L+G  P+ +              K    P  W 
Sbjct: 394 EVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWA 453

Query: 233 KIDSAPLALLHKILVENPSARITIPDIKKDRW 264
           ++    L L+ K+LV +P AR T  +  +  W
Sbjct: 454 EVSEKALDLVKKLLVVDPKARFTTEEALRHPW 485


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.136    0.415 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,988,679
Number of Sequences: 37866
Number of extensions: 886360
Number of successful extensions: 4270
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 713
Number of HSP's successfully gapped in prelim test: 97
Number of HSP's that attempted gapping in prelim test: 2009
Number of HSP's gapped (non-prelim): 927
length of query: 476
length of database: 18,247,518
effective HSP length: 106
effective length of query: 370
effective length of database: 14,233,722
effective search space: 5266477140
effective search space used: 5266477140
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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