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Search of human proteins with 16507243
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|16507243 GSK-3 binding protein FRAT2 [Homo sapiens]
(233 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|16507243 GSK-3 binding protein FRAT2 [Homo sapiens] 465 e-131
gi|31317236 GSK-3 binding protein FRAT1 [Homo sapiens] 337 4e-93
gi|20986497 mitogen-activated protein kinase 7 isoform 1 [Homo s... 44 1e-04
gi|209529736 mitogen-activated protein kinase 7 isoform 1 [Homo ... 44 1e-04
gi|209529734 mitogen-activated protein kinase 7 isoform 1 [Homo ... 44 1e-04
gi|20986499 mitogen-activated protein kinase 7 isoform 2 [Homo s... 44 1e-04
gi|116268127 kinase non-catalytic C-lobe domain (KIND) containin... 43 2e-04
gi|167466201 WAS protein family homolog 1 [Homo sapiens] 42 3e-04
gi|239743666 PREDICTED: hypothetical protein XP_002342940 isofor... 42 5e-04
gi|239743664 PREDICTED: hypothetical protein XP_002342939 isofor... 42 5e-04
gi|110832843 TBP-associated factor 4 [Homo sapiens] 40 0.001
gi|169211815 PREDICTED: keratin associated protein 4.6 [Homo sap... 40 0.002
gi|239745807 PREDICTED: keratin associated protein 4-9 [Homo sap... 39 0.003
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 39 0.003
gi|117938318 vacuolar protein sorting 37D [Homo sapiens] 39 0.003
gi|55956788 nucleolin [Homo sapiens] 39 0.004
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 39 0.004
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 39 0.005
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 39 0.005
gi|118498345 AT-binding transcription factor 1 [Homo sapiens] 39 0.005
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 39 0.005
gi|45387951 transmembrane protein 108 [Homo sapiens] 39 0.005
gi|210147493 transmembrane protein 108 [Homo sapiens] 39 0.005
gi|4503519 eukaryotic translation initiation factor 3, subunit 5... 38 0.007
gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Hom... 38 0.008
gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Hom... 38 0.008
gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo ... 38 0.008
gi|24431933 reticulon 4 isoform B [Homo sapiens] 38 0.008
gi|47519490 reticulon 4 isoform D [Homo sapiens] 38 0.008
gi|24431935 reticulon 4 isoform A [Homo sapiens] 38 0.008
>gi|16507243 GSK-3 binding protein FRAT2 [Homo sapiens]
Length = 233
Score = 465 bits (1196), Expect = e-131
Identities = 233/233 (100%), Positives = 233/233 (100%)
Query: 1 MPCRREEEEEAGEEAEGEEEEDDSFLLLQQSVTLGSSGEVDRLVAQIGETLQLDAAQDSP 60
MPCRREEEEEAGEEAEGEEEEDDSFLLLQQSVTLGSSGEVDRLVAQIGETLQLDAAQDSP
Sbjct: 1 MPCRREEEEEAGEEAEGEEEEDDSFLLLQQSVTLGSSGEVDRLVAQIGETLQLDAAQDSP 60
Query: 61 ASPCAPPGVPLRAPGPLAAAVPADKARPPAVPLLLPPASAETVGPAPSGALRCALGDRGR 120
ASPCAPPGVPLRAPGPLAAAVPADKARPPAVPLLLPPASAETVGPAPSGALRCALGDRGR
Sbjct: 61 ASPCAPPGVPLRAPGPLAAAVPADKARPPAVPLLLPPASAETVGPAPSGALRCALGDRGR 120
Query: 121 VRGRAAPYCVAEVAAGPSALPGPCRRGWLRDAVTSRRLQQRRWTQAGARAGDDDPHRLLQ 180
VRGRAAPYCVAEVAAGPSALPGPCRRGWLRDAVTSRRLQQRRWTQAGARAGDDDPHRLLQ
Sbjct: 121 VRGRAAPYCVAEVAAGPSALPGPCRRGWLRDAVTSRRLQQRRWTQAGARAGDDDPHRLLQ 180
Query: 181 QLVLSGNLIKEAVRRLQRAVAAVAATGPASAPGPGGGRSGPDRIALQPSGSLL 233
QLVLSGNLIKEAVRRLQRAVAAVAATGPASAPGPGGGRSGPDRIALQPSGSLL
Sbjct: 181 QLVLSGNLIKEAVRRLQRAVAAVAATGPASAPGPGGGRSGPDRIALQPSGSLL 233
>gi|31317236 GSK-3 binding protein FRAT1 [Homo sapiens]
Length = 279
Score = 337 bits (865), Expect = 4e-93
Identities = 181/243 (74%), Positives = 185/243 (76%), Gaps = 31/243 (12%)
Query: 1 MPCRREEEEEAGEEAEGEEEEDDSFLLLQQSVTLGSSGEVDRLVAQIGETLQLDAAQDSP 60
MPCRREEEEEAGEEAEGEEEE+DSFLLLQQSV LGSSGEVDRLVAQIGETLQLDAAQ SP
Sbjct: 1 MPCRREEEEEAGEEAEGEEEEEDSFLLLQQSVALGSSGEVDRLVAQIGETLQLDAAQHSP 60
Query: 61 ASPCAPPGVPLRAPGPLAAAVPADKARPPAVPLLLPPASAETVGPAPSGALRCALGDRGR 120
ASPC PPG PLRAPGPLAAAVPADKAR PAVPLLLPPA AETVGPAP G LRCALGDRGR
Sbjct: 61 ASPCGPPGAPLRAPGPLAAAVPADKARSPAVPLLLPPALAETVGPAPPGVLRCALGDRGR 120
Query: 121 VRGRAAPYCVAEVAAGPSA------------------------LPGPCRRGWLRDAVTSR 156
VRGRAAPYCVAE+A GPSA L GPCRRGWLR A SR
Sbjct: 121 VRGRAAPYCVAELATGPSALSPLPPQADLDGPPGAGKQGIPQPLSGPCRRGWLRGAAASR 180
Query: 157 RLQQRRWTQAGARAGDDDPHRLLQQLVLSGNLIKEAVRRLQRAVAAVAA-------TGPA 209
RLQQRR +Q R GDDDPHRLLQQLVLSGNLIKEAVRRL + A GP
Sbjct: 181 RLQQRRGSQPETRTGDDDPHRLLQQLVLSGNLIKEAVRRLHSRRLQLRAKLPQRPLLGPL 240
Query: 210 SAP 212
SAP
Sbjct: 241 SAP 243
>gi|20986497 mitogen-activated protein kinase 7 isoform 1 [Homo
sapiens]
Length = 816
Score = 43.9 bits (102), Expect = 1e-04
Identities = 50/170 (29%), Positives = 64/170 (37%), Gaps = 14/170 (8%)
Query: 59 SPASPCA---PPGVPLRAPGPLAAAVPADKARPPAVPLLLPPASAETVGPAPSGALRCAL 115
+P+ CA PP P PGP + PP V PP + AL+ AL
Sbjct: 424 APSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAAL 483
Query: 116 --GDRGRVR-GRAAPYCVAEVAAGPSA------LPGPCRRGWLRDAVTSRRLQQRRWTQA 166
R R+R G +AP E +A RR R +R Q+R +
Sbjct: 484 LKSLRSRLRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKER 543
Query: 167 GARAGDDDPHRLLQQLVLSGN--LIKEAVRRLQRAVAAVAATGPASAPGP 214
GA A L LVLS N + E R+ R A + PA AP P
Sbjct: 544 GAGASGGPSTDPLAGLVLSDNDRSLLERWTRMARPAAPALTSVPAPAPAP 593
Score = 31.2 bits (69), Expect = 0.79
Identities = 22/57 (38%), Positives = 23/57 (40%), Gaps = 7/57 (12%)
Query: 61 ASPCAPP--GVPLRAPGPLAAAVPADKARPPAVPLLLP----PASA-ETVGPAPSGA 110
A P AP VP AP P P PP P+ P P SA T GP P A
Sbjct: 576 ARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPA 632
>gi|209529736 mitogen-activated protein kinase 7 isoform 1 [Homo
sapiens]
Length = 816
Score = 43.9 bits (102), Expect = 1e-04
Identities = 50/170 (29%), Positives = 64/170 (37%), Gaps = 14/170 (8%)
Query: 59 SPASPCA---PPGVPLRAPGPLAAAVPADKARPPAVPLLLPPASAETVGPAPSGALRCAL 115
+P+ CA PP P PGP + PP V PP + AL+ AL
Sbjct: 424 APSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAAL 483
Query: 116 --GDRGRVR-GRAAPYCVAEVAAGPSA------LPGPCRRGWLRDAVTSRRLQQRRWTQA 166
R R+R G +AP E +A RR R +R Q+R +
Sbjct: 484 LKSLRSRLRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKER 543
Query: 167 GARAGDDDPHRLLQQLVLSGN--LIKEAVRRLQRAVAAVAATGPASAPGP 214
GA A L LVLS N + E R+ R A + PA AP P
Sbjct: 544 GAGASGGPSTDPLAGLVLSDNDRSLLERWTRMARPAAPALTSVPAPAPAP 593
Score = 31.2 bits (69), Expect = 0.79
Identities = 22/57 (38%), Positives = 23/57 (40%), Gaps = 7/57 (12%)
Query: 61 ASPCAPP--GVPLRAPGPLAAAVPADKARPPAVPLLLP----PASA-ETVGPAPSGA 110
A P AP VP AP P P PP P+ P P SA T GP P A
Sbjct: 576 ARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPA 632
>gi|209529734 mitogen-activated protein kinase 7 isoform 1 [Homo
sapiens]
Length = 816
Score = 43.9 bits (102), Expect = 1e-04
Identities = 50/170 (29%), Positives = 64/170 (37%), Gaps = 14/170 (8%)
Query: 59 SPASPCA---PPGVPLRAPGPLAAAVPADKARPPAVPLLLPPASAETVGPAPSGALRCAL 115
+P+ CA PP P PGP + PP V PP + AL+ AL
Sbjct: 424 APSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAAL 483
Query: 116 --GDRGRVR-GRAAPYCVAEVAAGPSA------LPGPCRRGWLRDAVTSRRLQQRRWTQA 166
R R+R G +AP E +A RR R +R Q+R +
Sbjct: 484 LKSLRSRLRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKER 543
Query: 167 GARAGDDDPHRLLQQLVLSGN--LIKEAVRRLQRAVAAVAATGPASAPGP 214
GA A L LVLS N + E R+ R A + PA AP P
Sbjct: 544 GAGASGGPSTDPLAGLVLSDNDRSLLERWTRMARPAAPALTSVPAPAPAP 593
Score = 31.2 bits (69), Expect = 0.79
Identities = 22/57 (38%), Positives = 23/57 (40%), Gaps = 7/57 (12%)
Query: 61 ASPCAPP--GVPLRAPGPLAAAVPADKARPPAVPLLLP----PASA-ETVGPAPSGA 110
A P AP VP AP P P PP P+ P P SA T GP P A
Sbjct: 576 ARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPA 632
>gi|20986499 mitogen-activated protein kinase 7 isoform 2 [Homo
sapiens]
Length = 677
Score = 43.9 bits (102), Expect = 1e-04
Identities = 50/170 (29%), Positives = 64/170 (37%), Gaps = 14/170 (8%)
Query: 59 SPASPCA---PPGVPLRAPGPLAAAVPADKARPPAVPLLLPPASAETVGPAPSGALRCAL 115
+P+ CA PP P PGP + PP V PP + AL+ AL
Sbjct: 285 APSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALKAAL 344
Query: 116 --GDRGRVR-GRAAPYCVAEVAAGPSA------LPGPCRRGWLRDAVTSRRLQQRRWTQA 166
R R+R G +AP E +A RR R +R Q+R +
Sbjct: 345 LKSLRSRLRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERERKER 404
Query: 167 GARAGDDDPHRLLQQLVLSGN--LIKEAVRRLQRAVAAVAATGPASAPGP 214
GA A L LVLS N + E R+ R A + PA AP P
Sbjct: 405 GAGASGGPSTDPLAGLVLSDNDRSLLERWTRMARPAAPALTSVPAPAPAP 454
Score = 31.2 bits (69), Expect = 0.79
Identities = 22/57 (38%), Positives = 23/57 (40%), Gaps = 7/57 (12%)
Query: 61 ASPCAPP--GVPLRAPGPLAAAVPADKARPPAVPLLLP----PASA-ETVGPAPSGA 110
A P AP VP AP P P PP P+ P P SA T GP P A
Sbjct: 437 ARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPA 493
>gi|116268127 kinase non-catalytic C-lobe domain (KIND) containing 1
isoform a [Homo sapiens]
Length = 1749
Score = 43.1 bits (100), Expect = 2e-04
Identities = 39/124 (31%), Positives = 52/124 (41%), Gaps = 15/124 (12%)
Query: 5 REEEEEAGEEAEGEEEEDDSFLLLQQSVTLGSS-------GEVDRLVAQIGETLQLDAAQ 57
+EE EE G + EGE EE S S +L + G +G ++Q D+AQ
Sbjct: 697 QEESEERGGQREGEGEEKLSLEAHAGSPSLKTPDGPVPGPGPQGAAPEPLGASVQRDSAQ 756
Query: 58 DSPASPCAPPGVPLRAPGPLAAA-----VPADKARPPAVPLLLPPASAETVGPAPSGALR 112
PC PP P P ++A VPA + A+P+ PA G A G
Sbjct: 757 ---GRPCPPPQAPANQPEGASSAAPGSPVPAPPTKASALPVEQGPAEPIPPGVASGGLRP 813
Query: 113 CALG 116
ALG
Sbjct: 814 DALG 817
>gi|167466201 WAS protein family homolog 1 [Homo sapiens]
Length = 465
Score = 42.4 bits (98), Expect = 3e-04
Identities = 44/182 (24%), Positives = 75/182 (41%), Gaps = 21/182 (11%)
Query: 35 GSSGEVDRLVAQIGETLQLDAAQDSPASPCAPPGVPLRAPGPLAAAVPADKARPPAVPLL 94
G+ E+ ++ E L++D QD +P PP P AP LA+A P
Sbjct: 276 GTIPELPTFHTEVAEPLKVDL-QDGVLTPPPPPPPPPPAPEVLASAPP------------ 322
Query: 95 LPPASAETVGPAPSGALRCALGDRGRVRGRAAPYCVAEVAAGPSALPGPCRRGWLRDAVT 154
LPP++A VG GA + + AP V + + G + L R+
Sbjct: 323 LPPSTAAPVG---QGARQDDSSSSASPSVQGAPREVVDPSGGRATLLESIRQAGGIGKAK 379
Query: 155 SRRLQQRRWTQAGARAGDDDPHRLLQQLVLSGNLIKEAVRRLQRAVAAVAATGPASAPGP 214
R +++R+ + + + + R Q G+L+ + +L ++ GP + GP
Sbjct: 380 LRSVKERKLEKKKQK--EQEQVRATSQ---GGDLMSDLFNKLVMRRKGISGKGPGAGEGP 434
Query: 215 GG 216
GG
Sbjct: 435 GG 436
>gi|239743666 PREDICTED: hypothetical protein XP_002342940 isoform 2
[Homo sapiens]
Length = 465
Score = 42.0 bits (97), Expect = 5e-04
Identities = 44/182 (24%), Positives = 75/182 (41%), Gaps = 21/182 (11%)
Query: 35 GSSGEVDRLVAQIGETLQLDAAQDSPASPCAPPGVPLRAPGPLAAAVPADKARPPAVPLL 94
G+ E+ ++ E L++D QD +P PP P AP LA+A P
Sbjct: 276 GTIPELPTFHTEVAEPLKVDL-QDGVLTPPPPPPPPPPAPEVLASAPP------------ 322
Query: 95 LPPASAETVGPAPSGALRCALGDRGRVRGRAAPYCVAEVAAGPSALPGPCRRGWLRDAVT 154
LPP++A VG GA + + AP V + + G + L R+
Sbjct: 323 LPPSTAAPVG---QGARQDDSSSSASPSVQGAPREVVDPSGGWATLLESIRQAGGIGKAK 379
Query: 155 SRRLQQRRWTQAGARAGDDDPHRLLQQLVLSGNLIKEAVRRLQRAVAAVAATGPASAPGP 214
R +++R+ + + + + R Q G+L+ + +L ++ GP + GP
Sbjct: 380 LRSMKERKLEKQQQK--EQEQVRATSQ---GGHLMSDLFNKLVMRRKGISGKGPGAGEGP 434
Query: 215 GG 216
GG
Sbjct: 435 GG 436
>gi|239743664 PREDICTED: hypothetical protein XP_002342939 isoform 1
[Homo sapiens]
Length = 482
Score = 42.0 bits (97), Expect = 5e-04
Identities = 44/182 (24%), Positives = 75/182 (41%), Gaps = 21/182 (11%)
Query: 35 GSSGEVDRLVAQIGETLQLDAAQDSPASPCAPPGVPLRAPGPLAAAVPADKARPPAVPLL 94
G+ E+ ++ E L++D QD +P PP P AP LA+A P
Sbjct: 293 GTIPELPTFHTEVAEPLKVDL-QDGVLTPPPPPPPPPPAPEVLASAPP------------ 339
Query: 95 LPPASAETVGPAPSGALRCALGDRGRVRGRAAPYCVAEVAAGPSALPGPCRRGWLRDAVT 154
LPP++A VG GA + + AP V + + G + L R+
Sbjct: 340 LPPSTAAPVG---QGARQDDSSSSASPSVQGAPREVVDPSGGWATLLESIRQAGGIGKAK 396
Query: 155 SRRLQQRRWTQAGARAGDDDPHRLLQQLVLSGNLIKEAVRRLQRAVAAVAATGPASAPGP 214
R +++R+ + + + + R Q G+L+ + +L ++ GP + GP
Sbjct: 397 LRSMKERKLEKQQQK--EQEQVRATSQ---GGHLMSDLFNKLVMRRKGISGKGPGAGEGP 451
Query: 215 GG 216
GG
Sbjct: 452 GG 453
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 40.4 bits (93), Expect = 0.001
Identities = 35/93 (37%), Positives = 39/93 (41%), Gaps = 12/93 (12%)
Query: 55 AAQDSPASPCAP----PGVPLRAPGPLAAAVPADKARPPAVPLLLPPASAETVGPAPSGA 110
AA +PA+P P P P AP P A PA ARPP P PP +A V P
Sbjct: 247 AAPPAPAAPSPPAAPAPAAPAAAPPPPPPA-PATLARPPGHP-AGPPTAAPAVPPP---- 300
Query: 111 LRCALGDRGRVRGRAAPYCVAEVAAGPSALPGP 143
A + G AP A AG S PGP
Sbjct: 301 --AAAQNGGSAGAAPAPAPAAGGPAGVSGQPGP 331
Score = 38.9 bits (89), Expect = 0.004
Identities = 31/82 (37%), Positives = 38/82 (46%), Gaps = 3/82 (3%)
Query: 56 AQDSPASPCAPPGVPLRAPGPLAAAVPADKARPP-AVPLLLPPASAETVGPAPSG-ALRC 113
A +PA+P A P P AP LA P A PP A P + PPA+A+ G A + A
Sbjct: 259 AAPAPAAPAAAPPPPPPAPATLARP-PGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAP 317
Query: 114 ALGDRGRVRGRAAPYCVAEVAA 135
A G V G+ P A A
Sbjct: 318 AAGGPAGVSGQPGPGAAAAAPA 339
Score = 37.7 bits (86), Expect = 0.008
Identities = 36/95 (37%), Positives = 42/95 (44%), Gaps = 8/95 (8%)
Query: 55 AAQDSPASPCAPPGVPLRAPGPLAAA---VPADKARPPAVPLLLPP-ASAETVGPAPSGA 110
A + PA P G + PGP + VPA A PPA L PP SA + P P+ A
Sbjct: 86 APEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPA-PPAAKLRPPPEGSAGSCAPVPAAA 144
Query: 111 LRCALGDRGRVRGRAAPYCVAEVA--AGPSALPGP 143
A G G A P A +A AGP PGP
Sbjct: 145 -AVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGP 178
Score = 28.9 bits (63), Expect = 3.9
Identities = 25/79 (31%), Positives = 28/79 (35%), Gaps = 12/79 (15%)
Query: 65 APPGVPLRAPGPLAAAVPADKARPPAVPLLLPPASAETVGPAPSGALRCALGDRGRVRGR 124
A P V L GP AA +P K P + PP PAP+
Sbjct: 211 AAPAVSLVNNGP-AALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAP-----------SPP 258
Query: 125 AAPYCVAEVAAGPSALPGP 143
AAP A AA P P P
Sbjct: 259 AAPAPAAPAAAPPPPPPAP 277
>gi|169211815 PREDICTED: keratin associated protein 4.6 [Homo
sapiens]
Length = 288
Score = 39.7 bits (91), Expect = 0.002
Identities = 36/91 (39%), Positives = 41/91 (45%), Gaps = 12/91 (13%)
Query: 55 AAQDSPASPCAPPGVPLRAPGPLAAAVPADKARPPAVPL-LLPPASAETVGPAPSGALRC 113
AA S AS CA P P + AAV A PPA L + PA+A+ PS A C
Sbjct: 124 AADPSAASLCAA-SPPAAVPAAVPAAVRPPAAGPPAAALAAVYPAAAD-----PSAASLC 177
Query: 114 ALGDRGRVRGRAAPYCVAEV-----AAGPSA 139
A V A+P VA AAGPSA
Sbjct: 178 AASPLAAVPAAASPAAVAPAAVCPGAAGPSA 208
Score = 36.2 bits (82), Expect = 0.025
Identities = 34/101 (33%), Positives = 45/101 (44%), Gaps = 17/101 (16%)
Query: 55 AAQDSPASPCA--PPGVPLRAPGPLAA---------AVPADKARPPAVPLLLPPASAETV 103
AA + ASP A P V A GP AA AVPA + A PL + PA+A
Sbjct: 183 AAVPAAASPAAVAPAAVCPGAAGPSAASLCAASQPAAVPAAASPAAAAPLAVNPAAAARA 242
Query: 104 GPAPSGALRCALGDRGRVRGRAAPYCVAEVAAGPSALPGPC 144
AP+ A ++ + A P +A+ + P A P PC
Sbjct: 243 AAAPAAACVQSVAE-----SPATPLAIAQPVSFPPA-PVPC 277
Score = 35.4 bits (80), Expect = 0.042
Identities = 34/95 (35%), Positives = 41/95 (43%), Gaps = 13/95 (13%)
Query: 55 AAQDSPASPCAPPGVPLRAPGPLAAAVPADKARPPAVPLLLPPASAE--TVGPA------ 106
AA PA+ PP L A P AAA P+ + A PL PA+A V PA
Sbjct: 147 AAVRPPAA--GPPAAALAAVYP-AAADPSAASLCAASPLAAVPAAASPAAVAPAAVCPGA 203
Query: 107 --PSGALRCALGDRGRVRGRAAPYCVAEVAAGPSA 139
PS A CA V A+P A +A P+A
Sbjct: 204 AGPSAASLCAASQPAAVPAAASPAAAAPLAVNPAA 238
Score = 33.5 bits (75), Expect = 0.16
Identities = 27/79 (34%), Positives = 30/79 (37%), Gaps = 1/79 (1%)
Query: 61 ASPCAPPGVPLRAPGPLAAAVPADKARPPAVPLLLPPASAETVGPAPSGALRCALGDRGR 120
++P P RA AA PA P A P PA+ PS A CA
Sbjct: 81 SAPVVVPSALTRAVAWRPAAAPAAVRPPAAGPPAAAPAAVCPAAADPSAASLCAASPPAA 140
Query: 121 VRGRAAPYCVAEVAAGPSA 139
V A P V AAGP A
Sbjct: 141 VPA-AVPAAVRPPAAGPPA 158
>gi|239745807 PREDICTED: keratin associated protein 4-9 [Homo
sapiens]
Length = 254
Score = 39.3 bits (90), Expect = 0.003
Identities = 30/90 (33%), Positives = 37/90 (41%), Gaps = 10/90 (11%)
Query: 59 SPASPC----APPGVPLRAPGPLAAAVPADKARPPAV-----PLLLPPASAETVGPAPSG 109
+PA C P LRA PLA A PA RP A P + PA+ +PS
Sbjct: 75 APAVVCPAAAGPSAASLRAANPLAVA-PAAVRRPAATLGAASPAAVAPAAVCPAAASPSA 133
Query: 110 ALRCALGDRGRVRGRAAPYCVAEVAAGPSA 139
A CA A+P A +A P+A
Sbjct: 134 ASLCAASPTAAAPAAASPAAAAPLAVNPAA 163
Score = 33.5 bits (75), Expect = 0.16
Identities = 29/90 (32%), Positives = 43/90 (47%), Gaps = 16/90 (17%)
Query: 59 SPASPC----APPGVPLRAPGPLAAAVPADKARPPAVPLLLPPASAETVGPAPSGALRCA 114
+PA+ C +P L A P AAA PA + A PL + PA+A AP+ A +
Sbjct: 120 APAAVCPAAASPSAASLCAASPTAAA-PAAASPAAAAPLAVNPAAA-----APAAACVQS 173
Query: 115 LGDRGRVRGRAAPYCVAEVAAGPSALPGPC 144
+ + A P +A+ + P+A P PC
Sbjct: 174 VAE-----SPATPLAIAQPVSSPAA-PAPC 197
Score = 30.8 bits (68), Expect = 1.0
Identities = 30/80 (37%), Positives = 34/80 (42%), Gaps = 16/80 (20%)
Query: 71 LRAPGPLAAAVPADKARPPAV-PLLLPPASAETVGPAPSGALRCALGD--------RGRV 121
+R P AAV A PPA P ++ PA+A PS A CA R V
Sbjct: 14 VRRPAAAPAAVRPPAAGPPAAAPAVVYPAAA-----GPSAASLCAANPLVPAPAAVRPPV 68
Query: 122 RG--RAAPYCVAEVAAGPSA 139
G AP V AAGPSA
Sbjct: 69 AGPPATAPAVVCPAAAGPSA 88
Score = 27.7 bits (60), Expect = 8.8
Identities = 21/55 (38%), Positives = 25/55 (45%), Gaps = 3/55 (5%)
Query: 55 AAQDSPASPCA--PPGVPLRAPGPLAAAVPADKARPPAVPLLLPPASAETVGPAP 107
AA + ASP A P V A P AA V + A PA PL + + PAP
Sbjct: 143 AAAPAAASPAAAAPLAVNPAAAAPAAACVQS-VAESPATPLAIAQPVSSPAAPAP 196
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 39.3 bits (90), Expect = 0.003
Identities = 23/71 (32%), Positives = 32/71 (45%), Gaps = 16/71 (22%)
Query: 57 QDSPASPCAPPGVPLRAPGPLAA--------------AVPADKARPPAVPLLLPPASAET 102
Q+SP S C+PP +PL P PL+ + +K P P L P A++
Sbjct: 1035 QNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPL 1094
Query: 103 VGPAPSGALRC 113
P+P G L C
Sbjct: 1095 --PSPMGDLSC 1103
Score = 29.3 bits (64), Expect = 3.0
Identities = 20/62 (32%), Positives = 25/62 (40%), Gaps = 4/62 (6%)
Query: 66 PPGVPLRAPGPLAAAVPADKARPPAVPLLLPPASAETVGPAPSGALRCALGDRGRVRGRA 125
PP P P PLA + A PP PL+ P P PS + + R + RA
Sbjct: 4910 PPEEPSPPPSPLAPS----PASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRA 4965
Query: 126 AP 127
P
Sbjct: 4966 RP 4967
Score = 28.5 bits (62), Expect = 5.2
Identities = 17/44 (38%), Positives = 23/44 (52%), Gaps = 4/44 (9%)
Query: 67 PGVPLRAP---GPLAAAVPADKARP-PAVPLLLPPASAETVGPA 106
P PL AP P++ A+ P P P++LPP+ VGPA
Sbjct: 969 PESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPA 1012
>gi|117938318 vacuolar protein sorting 37D [Homo sapiens]
Length = 251
Score = 39.3 bits (90), Expect = 0.003
Identities = 41/122 (33%), Positives = 56/122 (45%), Gaps = 21/122 (17%)
Query: 7 EEEEAGEEAEGEEEEDDSFLLLQQSV-TLGSSGEVDRLVAQIGETL----------QLDA 55
E EEA +EAE E+ + LL +QS+ + + R +A + T + +
Sbjct: 122 ELEEAEQEAE---EQMEQLLLGEQSLEAFLPAFQRGRALAHLRRTQAEKLQELLRRRERS 178
Query: 56 AQDSPASPCAPPGVPLRAPGPLAAAVPADKAR-PPAVPLLLPPASAETVGPAPSGALRCA 114
AQ +P S PP P AA +P AR PPAVP LPP + V P G+ C
Sbjct: 179 AQPAPTSAADPP-----KSFPAAAVLPTGAARGPPAVPRSLPPLDSRPVPPL-KGSPGCP 232
Query: 115 LG 116
LG
Sbjct: 233 LG 234
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 38.9 bits (89), Expect = 0.004
Identities = 39/134 (29%), Positives = 53/134 (39%), Gaps = 21/134 (15%)
Query: 2 PCRREEEEEAGEEAEGEEEEDDSFLLLQQSVTLGSSGEVDRLVAQIGETLQLDAAQDSPA 61
P +E EE++ +E E+EEDD SSGE + + G+ +A+
Sbjct: 19 PPPKEVEEDSEDEEMSEDEEDD------------SSGEEVVIPQKKGKKAAATSAKKVVV 66
Query: 62 SPCAPPGVPLRA------PGPLAAAVPADKARPPAVPLLLPPASAETVGP---APSGALR 112
SP V A PG AAA PA K PA + P T G A G
Sbjct: 67 SPTKKVAVATPAKKAAVTPGKKAAATPAKKTVTPAKAVTTPGKKGATPGKALVATPGKKG 126
Query: 113 CALGDRGRVRGRAA 126
A+ +G G+ A
Sbjct: 127 AAIPAKGAKNGKNA 140
>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
Length = 538
Score = 38.9 bits (89), Expect = 0.004
Identities = 39/122 (31%), Positives = 47/122 (38%), Gaps = 10/122 (8%)
Query: 60 PASPCAPPGVPLRAPGPLAAAVPADKAR-PPAVPLLLPPASAETVGPAPSGALRCALGDR 118
P +P APP V A GP A PA AR PP P PPA + P P G
Sbjct: 181 PPAPAAPPAVAPPA-GPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGA 239
Query: 119 GRVRGRAAPYCVAEVA---AGPSALPGPCRRGWLR-----DAVTSRRLQQRRWTQAGARA 170
R G A P + EV G G RG ++ +A RL++ R
Sbjct: 240 VRAGGAARPVSLREVVRYLGGSGGAGGRLTRGRVQGLLEEEAAARGRLERTRLGALALPR 299
Query: 171 GD 172
GD
Sbjct: 300 GD 301
Score = 37.7 bits (86), Expect = 0.008
Identities = 30/83 (36%), Positives = 33/83 (39%), Gaps = 6/83 (7%)
Query: 61 ASPCAPPGVPLRAPGPLAAAVPADKARPPAVPLLLPPASAETVGPAPSGALRCALGDRGR 120
A+P APP P AP AAA P PP PPA PA + A
Sbjct: 106 ATPPAPPRAPRGAPAAAAAAAPPPTPAPPP-----PPAPVAAAAPARAPRAAAAAATAPP 160
Query: 121 VRGRAAPYCVAEVAAGPSALPGP 143
G A P A+ AA P A P P
Sbjct: 161 SPGPAQPGPRAQRAA-PLAAPPP 182
Score = 33.5 bits (75), Expect = 0.16
Identities = 34/99 (34%), Positives = 37/99 (37%), Gaps = 20/99 (20%)
Query: 60 PASPCAPPGVPLRA--------------PGPLAAAVPADKARPPAVPLLLPPASAETVGP 105
PA P AP G P A P P+AAA PA R A PP+ GP
Sbjct: 109 PAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSP----GP 164
Query: 106 A-PSGALRCALGDRGRVRGRAAPYCVAEVAAGPSALPGP 143
A P + A AAP VA AGP P P
Sbjct: 165 AQPGPRAQRAAPLAAPPPAPAAPPAVAP-PAGPRRAPPP 202
Score = 30.0 bits (66), Expect = 1.8
Identities = 27/80 (33%), Positives = 27/80 (33%), Gaps = 10/80 (12%)
Query: 60 PASPCAPPGVPLRAPGPLAAAVPADKARPPAVPLLLPPASAETVGPAPSGALRCALGDRG 119
P PP P RAP AA A A PP P PP PAP A A R
Sbjct: 102 PRRGATPPAPP-RAPRGAPAAAAA--AAPPPTPAPPPP-------PAPVAAAAPARAPRA 151
Query: 120 RVRGRAAPYCVAEVAAGPSA 139
AP GP A
Sbjct: 152 AAAAATAPPSPGPAQPGPRA 171
Score = 30.0 bits (66), Expect = 1.8
Identities = 32/93 (34%), Positives = 37/93 (39%), Gaps = 8/93 (8%)
Query: 55 AAQDSPASPCAPPGV----PLRAPGPLAAAVPADKARPPAVPLLLPPASAETVGPAPSGA 110
A +PA P P V P RAP AAA A + PA P +A P P+ A
Sbjct: 126 APPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPA 185
Query: 111 LRCALGDRGRVRGRAAPYCVAEVAAGPSALPGP 143
A+ R RA P VAA LP P
Sbjct: 186 APPAVAPPAGPR-RAPP---PAVAAREPPLPPP 214
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 38.5 bits (88), Expect = 0.005
Identities = 26/73 (35%), Positives = 36/73 (49%), Gaps = 9/73 (12%)
Query: 37 SGEVDRLVAQIGETLQLDAAQDSPASPCAPPGVPLRAPGPLAAAVPADKAR--PPAVPLL 94
+GEV +L ++ E + + A S A+ PP VP RAP P A +P D PP
Sbjct: 536 TGEVAKLTKEL-EDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPP----- 589
Query: 95 LPPASAETVGPAP 107
PPA ++ P P
Sbjct: 590 -PPAPGDSTTPPP 601
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 38.5 bits (88), Expect = 0.005
Identities = 26/73 (35%), Positives = 36/73 (49%), Gaps = 9/73 (12%)
Query: 37 SGEVDRLVAQIGETLQLDAAQDSPASPCAPPGVPLRAPGPLAAAVPADKAR--PPAVPLL 94
+GEV +L ++ E + + A S A+ PP VP RAP P A +P D PP
Sbjct: 545 TGEVAKLTKEL-EDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPP----- 598
Query: 95 LPPASAETVGPAP 107
PPA ++ P P
Sbjct: 599 -PPAPGDSTTPPP 610
>gi|118498345 AT-binding transcription factor 1 [Homo sapiens]
Length = 3703
Score = 38.5 bits (88), Expect = 0.005
Identities = 20/47 (42%), Positives = 25/47 (53%), Gaps = 1/47 (2%)
Query: 60 PASPCAPPGVPLRAPGPLAAAVPADKARPPAVPLLLPPASAETVGPA 106
P +P PP P P PL AA P A PA+P PP ++ T+ PA
Sbjct: 2034 PQTPEPPPPPPPPPPPPLPAA-PPQPASTPAIPASAPPITSPTIAPA 2079
Score = 28.9 bits (63), Expect = 3.9
Identities = 13/18 (72%), Positives = 15/18 (83%)
Query: 6 EEEEEAGEEAEGEEEEDD 23
EEEEEA EE E EEEE++
Sbjct: 467 EEEEEAEEEEEEEEEEEE 484
Score = 27.7 bits (60), Expect = 8.8
Identities = 12/18 (66%), Positives = 14/18 (77%)
Query: 6 EEEEEAGEEAEGEEEEDD 23
EEEEE EE E EEEE++
Sbjct: 466 EEEEEEAEEEEEEEEEEE 483
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 38.5 bits (88), Expect = 0.005
Identities = 35/144 (24%), Positives = 62/144 (43%), Gaps = 8/144 (5%)
Query: 2 PCRREEEEEAGEEAEGEEEEDDSFLLLQQSVTLGSSGEVDRLVAQIGETLQLDAAQDSPA 61
PC +++E++ +E E ++EE++ ++ + E+ + A E +L +P
Sbjct: 352 PCWKKQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEM--MPAAEKEEAKLPPPPLTPP 409
Query: 62 SPCAPPGVP--LRAPGPLAAAVPADKARPPAVPLLLPPASAETVGPAPSGALRCALGDRG 119
+P PP +P +P P P PP +P PP + E +P +
Sbjct: 410 APSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATC---S 466
Query: 120 RVRGRAAPYCVAEVAAGPSALPGP 143
R RGR P ++ A +A GP
Sbjct: 467 RKRGR-PPLTPSQRAEREAARAGP 489
>gi|45387951 transmembrane protein 108 [Homo sapiens]
Length = 575
Score = 38.5 bits (88), Expect = 0.005
Identities = 25/84 (29%), Positives = 38/84 (45%), Gaps = 8/84 (9%)
Query: 66 PPGVPLRAPGPLAAAVPADKARPP-------AVPLLLPPA-SAETVGPAPSGALRCALGD 117
P G P +A P+A P + PP A + P + S+ + GPAP+ +
Sbjct: 70 PDGPPSQAAAPMATPTPRAEGHPPTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKP 129
Query: 118 RGRVRGRAAPYCVAEVAAGPSALP 141
GR RG+AAP + G ++ P
Sbjct: 130 EGRPRGQAAPTILLTKPPGATSRP 153
>gi|210147493 transmembrane protein 108 [Homo sapiens]
Length = 575
Score = 38.5 bits (88), Expect = 0.005
Identities = 25/84 (29%), Positives = 38/84 (45%), Gaps = 8/84 (9%)
Query: 66 PPGVPLRAPGPLAAAVPADKARPP-------AVPLLLPPA-SAETVGPAPSGALRCALGD 117
P G P +A P+A P + PP A + P + S+ + GPAP+ +
Sbjct: 70 PDGPPSQAAAPMATPTPRAEGHPPTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKP 129
Query: 118 RGRVRGRAAPYCVAEVAAGPSALP 141
GR RG+AAP + G ++ P
Sbjct: 130 EGRPRGQAAPTILLTKPPGATSRP 153
>gi|4503519 eukaryotic translation initiation factor 3, subunit 5
epsilon, 47kDa [Homo sapiens]
Length = 357
Score = 38.1 bits (87), Expect = 0.007
Identities = 26/84 (30%), Positives = 30/84 (35%), Gaps = 1/84 (1%)
Query: 61 ASPCAPPGVPLRAPGPLAAAVPADKARPPAVPLLLP-PASAETVGPAPSGALRCALGDRG 119
A+P P P P P+ AA PA P P P PA+A P+ A
Sbjct: 2 ATPAVPVSAPPATPTPVPAAAPASVPAPTPAPAAAPVPAAAPASSSDPAAAAAATAAPGQ 61
Query: 120 RVRGRAAPYCVAEVAAGPSALPGP 143
AP A ALPGP
Sbjct: 62 TPASAQAPAQTPAPALPGPALPGP 85
Score = 35.4 bits (80), Expect = 0.042
Identities = 26/83 (31%), Positives = 31/83 (37%), Gaps = 5/83 (6%)
Query: 65 APPGVPLRAPGPLAAAVPADKARPPAVPLLLPPASAETVGPAPSGALRCALGDRGRVRGR 124
A P VP+ AP VPA A P +VP P A P P+ A +
Sbjct: 2 ATPAVPVSAPPATPTPVPA--AAPASVP---APTPAPAAAPVPAAAPASSSDPAAAAAAT 56
Query: 125 AAPYCVAEVAAGPSALPGPCRRG 147
AAP A P+ P P G
Sbjct: 57 AAPGQTPASAQAPAQTPAPALPG 79
>gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Homo
sapiens]
Length = 305
Score = 37.7 bits (86), Expect = 0.008
Identities = 31/87 (35%), Positives = 35/87 (40%), Gaps = 17/87 (19%)
Query: 60 PASPCAPPGVPLRAPGPLA--AAVPADKARPPAVPLLLP-PASAETVGPAPSGALRCALG 116
PA PP VP+ AP P A V A A P AV +L P PA A PAP+
Sbjct: 131 PAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPV------ 184
Query: 117 DRGRVRGRAAPYCVAEVAAGPSALPGP 143
AAP A P+ P P
Sbjct: 185 --------AAPAPAPAPAPAPAPAPAP 203
Score = 33.9 bits (76), Expect = 0.12
Identities = 31/97 (31%), Positives = 40/97 (41%), Gaps = 20/97 (20%)
Query: 53 LDAAQDSPASPCAPPGVPLRAPG------PLAAAVPADKARPPAVPLLLPPASAETVGPA 106
LD +++P P VP+ AP P+ A PA P A P+ P A A + PA
Sbjct: 115 LDGLEEAPEQL---PSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVA-VLAPA 170
Query: 107 PSGALRCALGDRGRVRGRAAPYCVAEVAAGPSALPGP 143
P+ A A AP VA A P+ P P
Sbjct: 171 PAPAPAPA----------PAPAPVAAPAPAPAPAPAP 197
Score = 32.7 bits (73), Expect = 0.27
Identities = 20/55 (36%), Positives = 24/55 (43%), Gaps = 3/55 (5%)
Query: 59 SPASPCAPPGVPLRAPGPLAAAVPADKARPPAVPLLLP---PASAETVGPAPSGA 110
+PA AP P+ AP +A PA P P P PA A PAP+ A
Sbjct: 146 APAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPA 200
Score = 32.7 bits (73), Expect = 0.27
Identities = 18/47 (38%), Positives = 20/47 (42%)
Query: 55 AAQDSPASPCAPPGVPLRAPGPLAAAVPADKARPPAVPLLLPPASAE 101
A +PA AP P+ AP P A PA P P P SAE
Sbjct: 168 APAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAE 214
Score = 32.7 bits (73), Expect = 0.27
Identities = 29/91 (31%), Positives = 33/91 (36%), Gaps = 15/91 (16%)
Query: 65 APPGVPLRAPGPLAAAVPADKARPPAVPLLLPPASAETVGPAPSGALRCALGDRGR---- 120
AP P AP P+AA PA P P PA A P S G RG+
Sbjct: 172 APAPAPAPAPAPVAAPAPAPAPAPAPAP---APAPAPDAAPQESAEQGANQGQRGQEPLA 228
Query: 121 ------VRGRAAPYCVAEVAAGPS--ALPGP 143
+ GR A A A G + L GP
Sbjct: 229 DQLHSGISGRPAAGTAAASANGAAIKKLSGP 259
>gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Homo
sapiens]
Length = 305
Score = 37.7 bits (86), Expect = 0.008
Identities = 31/87 (35%), Positives = 35/87 (40%), Gaps = 17/87 (19%)
Query: 60 PASPCAPPGVPLRAPGPLA--AAVPADKARPPAVPLLLP-PASAETVGPAPSGALRCALG 116
PA PP VP+ AP P A V A A P AV +L P PA A PAP+
Sbjct: 131 PAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPV------ 184
Query: 117 DRGRVRGRAAPYCVAEVAAGPSALPGP 143
AAP A P+ P P
Sbjct: 185 --------AAPAPAPAPAPAPAPAPAP 203
Score = 33.9 bits (76), Expect = 0.12
Identities = 31/97 (31%), Positives = 40/97 (41%), Gaps = 20/97 (20%)
Query: 53 LDAAQDSPASPCAPPGVPLRAPG------PLAAAVPADKARPPAVPLLLPPASAETVGPA 106
LD +++P P VP+ AP P+ A PA P A P+ P A A + PA
Sbjct: 115 LDGLEEAPEQL---PSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVA-VLAPA 170
Query: 107 PSGALRCALGDRGRVRGRAAPYCVAEVAAGPSALPGP 143
P+ A A AP VA A P+ P P
Sbjct: 171 PAPAPAPA----------PAPAPVAAPAPAPAPAPAP 197
Score = 32.7 bits (73), Expect = 0.27
Identities = 20/55 (36%), Positives = 24/55 (43%), Gaps = 3/55 (5%)
Query: 59 SPASPCAPPGVPLRAPGPLAAAVPADKARPPAVPLLLP---PASAETVGPAPSGA 110
+PA AP P+ AP +A PA P P P PA A PAP+ A
Sbjct: 146 APAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPA 200
Score = 32.7 bits (73), Expect = 0.27
Identities = 18/47 (38%), Positives = 20/47 (42%)
Query: 55 AAQDSPASPCAPPGVPLRAPGPLAAAVPADKARPPAVPLLLPPASAE 101
A +PA AP P+ AP P A PA P P P SAE
Sbjct: 168 APAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAE 214
Score = 32.7 bits (73), Expect = 0.27
Identities = 29/91 (31%), Positives = 33/91 (36%), Gaps = 15/91 (16%)
Query: 65 APPGVPLRAPGPLAAAVPADKARPPAVPLLLPPASAETVGPAPSGALRCALGDRGR---- 120
AP P AP P+AA PA P P PA A P S G RG+
Sbjct: 172 APAPAPAPAPAPVAAPAPAPAPAPAPAP---APAPAPDAAPQESAEQGANQGQRGQEPLA 228
Query: 121 ------VRGRAAPYCVAEVAAGPS--ALPGP 143
+ GR A A A G + L GP
Sbjct: 229 DQLHSGISGRPAAGTAAASANGAAIKKLSGP 259
>gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo
sapiens]
Length = 316
Score = 37.7 bits (86), Expect = 0.008
Identities = 31/87 (35%), Positives = 35/87 (40%), Gaps = 17/87 (19%)
Query: 60 PASPCAPPGVPLRAPGPLA--AAVPADKARPPAVPLLLP-PASAETVGPAPSGALRCALG 116
PA PP VP+ AP P A V A A P AV +L P PA A PAP+
Sbjct: 142 PAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPV------ 195
Query: 117 DRGRVRGRAAPYCVAEVAAGPSALPGP 143
AAP A P+ P P
Sbjct: 196 --------AAPAPAPAPAPAPAPAPAP 214
Score = 33.9 bits (76), Expect = 0.12
Identities = 31/97 (31%), Positives = 40/97 (41%), Gaps = 20/97 (20%)
Query: 53 LDAAQDSPASPCAPPGVPLRAPG------PLAAAVPADKARPPAVPLLLPPASAETVGPA 106
LD +++P P VP+ AP P+ A PA P A P+ P A A + PA
Sbjct: 126 LDGLEEAPEQL---PSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVA-VLAPA 181
Query: 107 PSGALRCALGDRGRVRGRAAPYCVAEVAAGPSALPGP 143
P+ A A AP VA A P+ P P
Sbjct: 182 PAPAPAPA----------PAPAPVAAPAPAPAPAPAP 208
Score = 32.7 bits (73), Expect = 0.27
Identities = 20/55 (36%), Positives = 24/55 (43%), Gaps = 3/55 (5%)
Query: 59 SPASPCAPPGVPLRAPGPLAAAVPADKARPPAVPLLLP---PASAETVGPAPSGA 110
+PA AP P+ AP +A PA P P P PA A PAP+ A
Sbjct: 157 APAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPA 211
Score = 32.7 bits (73), Expect = 0.27
Identities = 18/47 (38%), Positives = 20/47 (42%)
Query: 55 AAQDSPASPCAPPGVPLRAPGPLAAAVPADKARPPAVPLLLPPASAE 101
A +PA AP P+ AP P A PA P P P SAE
Sbjct: 179 APAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAE 225
Score = 32.7 bits (73), Expect = 0.27
Identities = 29/91 (31%), Positives = 33/91 (36%), Gaps = 15/91 (16%)
Query: 65 APPGVPLRAPGPLAAAVPADKARPPAVPLLLPPASAETVGPAPSGALRCALGDRGR---- 120
AP P AP P+AA PA P P PA A P S G RG+
Sbjct: 183 APAPAPAPAPAPVAAPAPAPAPAPAPAP---APAPAPDAAPQESAEQGANQGQRGQEPLA 239
Query: 121 ------VRGRAAPYCVAEVAAGPS--ALPGP 143
+ GR A A A G + L GP
Sbjct: 240 DQLHSGISGRPAAGTAAASANGAAIKKLSGP 270
>gi|24431933 reticulon 4 isoform B [Homo sapiens]
Length = 373
Score = 37.7 bits (86), Expect = 0.008
Identities = 44/138 (31%), Positives = 56/138 (40%), Gaps = 33/138 (23%)
Query: 5 REEEEEAGEEAEGEEEED---DSFLLLQQSVTLGSSGEVDRLVAQIGETLQLDAAQD--S 59
RE E+E EE E EE+ED + +L++ G S G L +D D
Sbjct: 29 REPEDEEEEEEEEEEDEDEDLEELEVLERKPAAGLSAAPVPTAPAAGAPL-MDFGNDFVP 87
Query: 60 PAS----PCAPPGVPLRA----PGPLAAAVPA---------------DKARPPAVPLLLP 96
PA P APP P R P P+++ VPA + PPA P P
Sbjct: 88 PAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPP 147
Query: 97 PAS----AETVGPAPSGA 110
PAS AE V P+ A
Sbjct: 148 PASVSPQAEPVWTPPAPA 165
>gi|47519490 reticulon 4 isoform D [Homo sapiens]
Length = 392
Score = 37.7 bits (86), Expect = 0.008
Identities = 44/138 (31%), Positives = 56/138 (40%), Gaps = 33/138 (23%)
Query: 5 REEEEEAGEEAEGEEEED---DSFLLLQQSVTLGSSGEVDRLVAQIGETLQLDAAQD--S 59
RE E+E EE E EE+ED + +L++ G S G L +D D
Sbjct: 29 REPEDEEEEEEEEEEDEDEDLEELEVLERKPAAGLSAAPVPTAPAAGAPL-MDFGNDFVP 87
Query: 60 PAS----PCAPPGVPLRA----PGPLAAAVPA---------------DKARPPAVPLLLP 96
PA P APP P R P P+++ VPA + PPA P P
Sbjct: 88 PAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPP 147
Query: 97 PAS----AETVGPAPSGA 110
PAS AE V P+ A
Sbjct: 148 PASVSPQAEPVWTPPAPA 165
>gi|24431935 reticulon 4 isoform A [Homo sapiens]
Length = 1192
Score = 37.7 bits (86), Expect = 0.008
Identities = 44/138 (31%), Positives = 56/138 (40%), Gaps = 33/138 (23%)
Query: 5 REEEEEAGEEAEGEEEED---DSFLLLQQSVTLGSSGEVDRLVAQIGETLQLDAAQD--S 59
RE E+E EE E EE+ED + +L++ G S G L +D D
Sbjct: 29 REPEDEEEEEEEEEEDEDEDLEELEVLERKPAAGLSAAPVPTAPAAGAPL-MDFGNDFVP 87
Query: 60 PAS----PCAPPGVPLRA----PGPLAAAVPA---------------DKARPPAVPLLLP 96
PA P APP P R P P+++ VPA + PPA P P
Sbjct: 88 PAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPP 147
Query: 97 PAS----AETVGPAPSGA 110
PAS AE V P+ A
Sbjct: 148 PASVSPQAEPVWTPPAPA 165
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.133 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,881,286
Number of Sequences: 37866
Number of extensions: 701554
Number of successful extensions: 10094
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 209
Number of HSP's successfully gapped in prelim test: 619
Number of HSP's that attempted gapping in prelim test: 7213
Number of HSP's gapped (non-prelim): 2997
length of query: 233
length of database: 18,247,518
effective HSP length: 99
effective length of query: 134
effective length of database: 14,498,784
effective search space: 1942837056
effective search space used: 1942837056
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.