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Search of human proteins with 148613884
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148613884 netrin 1 [Homo sapiens]
(604 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148613884 netrin 1 [Homo sapiens] 1295 0.0
gi|5453810 netrin 3 [Homo sapiens] 674 0.0
gi|145309326 laminin, gamma 1 precursor [Homo sapiens] 443 e-124
gi|24308065 netrin 5 [Homo sapiens] 387 e-107
gi|110611156 laminin, gamma 3 precursor [Homo sapiens] 384 e-106
gi|93204871 netrin 4 [Homo sapiens] 297 2e-80
gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens] 256 5e-68
gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens] 256 5e-68
gi|167614504 laminin, beta 1 precursor [Homo sapiens] 254 1e-67
gi|21264602 laminin alpha 5 [Homo sapiens] 254 1e-67
gi|38788416 laminin, alpha 1 precursor [Homo sapiens] 248 9e-66
gi|119703755 laminin, beta 2 precursor [Homo sapiens] 247 3e-65
gi|143770880 laminin, beta 4 [Homo sapiens] 246 4e-65
gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s... 246 6e-65
gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa... 246 6e-65
gi|164414431 netrin G1 isoform 1 [Homo sapiens] 241 1e-63
gi|62868217 laminin, beta 3 precursor [Homo sapiens] 223 3e-58
gi|62868215 laminin, beta 3 precursor [Homo sapiens] 223 3e-58
gi|189083719 laminin, beta 3 precursor [Homo sapiens] 223 3e-58
gi|190014607 netrin G2 [Homo sapiens] 204 1e-52
gi|219842266 usherin isoform B [Homo sapiens] 196 7e-50
gi|219842259 usherin isoform A [Homo sapiens] 196 7e-50
gi|54312078 netrin G1 isoform 3 [Homo sapiens] 175 9e-44
gi|164414437 netrin G1 isoform 2 [Homo sapiens] 173 5e-43
gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens] 94 4e-19
gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens] 94 4e-19
gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens] 94 4e-19
gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens] 94 4e-19
gi|122937440 multiple EGF-like-domains 9 [Homo sapiens] 87 3e-17
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 84 3e-16
>gi|148613884 netrin 1 [Homo sapiens]
Length = 604
Score = 1295 bits (3350), Expect = 0.0
Identities = 604/604 (100%), Positives = 604/604 (100%)
Query: 1 MMRAVWEALAALAAVACLVGAVRGGPGLSMFAGQAAQPDPCSDENGHPRRCIPDFVNAAF 60
MMRAVWEALAALAAVACLVGAVRGGPGLSMFAGQAAQPDPCSDENGHPRRCIPDFVNAAF
Sbjct: 1 MMRAVWEALAALAAVACLVGAVRGGPGLSMFAGQAAQPDPCSDENGHPRRCIPDFVNAAF 60
Query: 61 GKDVRVSSTCGRPPARYCVVSERGEERLRSCHLCNASDPKKAHPPAFLTDLNNPHNLTCW 120
GKDVRVSSTCGRPPARYCVVSERGEERLRSCHLCNASDPKKAHPPAFLTDLNNPHNLTCW
Sbjct: 61 GKDVRVSSTCGRPPARYCVVSERGEERLRSCHLCNASDPKKAHPPAFLTDLNNPHNLTCW 120
Query: 121 QSENYLQFPHNVTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQ 180
QSENYLQFPHNVTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQ
Sbjct: 121 QSENYLQFPHNVTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQ 180
Query: 181 CRKMYNRPHRAPITKQNEQEAVCTDSHTDMRPLSGGLIAFSTLDGRPSAHDFDNSPVLQD 240
CRKMYNRPHRAPITKQNEQEAVCTDSHTDMRPLSGGLIAFSTLDGRPSAHDFDNSPVLQD
Sbjct: 181 CRKMYNRPHRAPITKQNEQEAVCTDSHTDMRPLSGGLIAFSTLDGRPSAHDFDNSPVLQD 240
Query: 241 WVTATDIRVAFSRLHTFGDENEDDSELARDSYFYAVSDLQVGGRCKCNGHAARCVRDRDD 300
WVTATDIRVAFSRLHTFGDENEDDSELARDSYFYAVSDLQVGGRCKCNGHAARCVRDRDD
Sbjct: 241 WVTATDIRVAFSRLHTFGDENEDDSELARDSYFYAVSDLQVGGRCKCNGHAARCVRDRDD 300
Query: 301 SLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLS 360
SLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLS
Sbjct: 301 SLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLS 360
Query: 361 GRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTT 420
GRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTT
Sbjct: 361 GRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTT 420
Query: 421 GQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVAPPTTAASSVEEPEDCDSYCKASK 480
GQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVAPPTTAASSVEEPEDCDSYCKASK
Sbjct: 421 GQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVAPPTTAASSVEEPEDCDSYCKASK 480
Query: 481 GKLKINMKKYCKKDYAVQIHILKADKAGDWWKFTVNIISVYKQGTSRIRRGDQSLWIRSR 540
GKLKINMKKYCKKDYAVQIHILKADKAGDWWKFTVNIISVYKQGTSRIRRGDQSLWIRSR
Sbjct: 481 GKLKINMKKYCKKDYAVQIHILKADKAGDWWKFTVNIISVYKQGTSRIRRGDQSLWIRSR 540
Query: 541 DIACKCPKIKPLKKYLLLGNAEDSPDQSGIVADKSSLVIQWRDTWARRLRKFQQREKKGK 600
DIACKCPKIKPLKKYLLLGNAEDSPDQSGIVADKSSLVIQWRDTWARRLRKFQQREKKGK
Sbjct: 541 DIACKCPKIKPLKKYLLLGNAEDSPDQSGIVADKSSLVIQWRDTWARRLRKFQQREKKGK 600
Query: 601 CKKA 604
CKKA
Sbjct: 601 CKKA 604
>gi|5453810 netrin 3 [Homo sapiens]
Length = 580
Score = 674 bits (1740), Expect = 0.0
Identities = 314/580 (54%), Positives = 406/580 (70%), Gaps = 29/580 (5%)
Query: 33 GQAAQPDPCSDENGHPRRCIPDFVNAAFGKDVRVSSTCGRPPARYCVVSERGEERLRSCH 92
G A DPC DE G PR C+P VNAA G++V SSTCGRP R
Sbjct: 22 GPPAPADPCHDEGGAPRGCVPGLVNAALGREVLASSTCGRPATR---------------- 65
Query: 93 LCNASDPKKAHPPAFLTDLNNPHNLTCWQSENYLQFPHNVTLTLSLGKKFEVTYVSLQFC 152
C+ASDP++AH PA LT + CW+SE+ + P NVTLT+ LGK FE+ +VSL+FC
Sbjct: 66 ACDASDPRRAHSPALLTSPGGTASPLCWRSESLPRAPLNVTLTVPLGKAFELVFVSLRFC 125
Query: 153 SPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMYNR-PHRAPITKQNEQEAVCTDSHTDMR 211
S P S+A+ KS D+GR+W P F+S+ C Y R P A EA+C + +
Sbjct: 126 SAPPASVALLKSQDHGRSWAPLGFFSSHCDLDYGRLPAPANGPAGPGPEALCFPAPL-AQ 184
Query: 212 PLSGGLIAFSTLDGRPSAHDFDNSPVLQDWVTATDIRVAFSRLHTFGDENEDDSELARDS 271
P GL+AFS D P D D+SPVLQDWVTATD+RV +R T GD + ++ +
Sbjct: 185 PDGSGLLAFSMQDSSPPGLDLDSSPVLQDWVTATDVRVVLTRPSTAGDPRDMEAVVP--- 241
Query: 272 YFYAVSDLQVGGRCKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRAT 331
Y YA +DLQVGGRCKCNGHA+RC+ D L+CDCRH T GP+C RCKPF+ DRPWQRAT
Sbjct: 242 YSYAATDLQVGGRCKCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRAT 301
Query: 332 AREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDM 391
ARE++ C+AC+CN HARRCRFNMELY+LSGR+SGGVCLNCRHNTAGRHCHYC+EG+YRD
Sbjct: 302 ARESHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDP 361
Query: 392 GKPITHRKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPC 451
G+ ++ R+AC+ACDCHPVGAAGKTCNQTTGQCPCKDGVTG+TCNRCA G+QQSRSP+APC
Sbjct: 362 GRALSDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGFQQSRSPVAPC 421
Query: 452 IKIPVAPPTTAASSVEEPEDCDSYCKASKGKLKINMKKYCKKDYAVQIHI-LKADKAGDW 510
+K P+ PT +S V +P+DCDS+CK ++G +I++KK+CKKDYAVQ+ + + + G W
Sbjct: 422 VKTPIPGPTEDSSPV-QPQDCDSHCKPARGSYRISLKKFCKKDYAVQVAVGARGEARGAW 480
Query: 511 WKFTVNIISVYKQGTSRIRRGDQSLWIRSRDIACKCPKIKPLKKYLLLGNAEDSPDQS-- 568
+F V +++V++ G R RRG +LW+ + D AC CP++ P ++YLLLG +
Sbjct: 481 TRFPVAVLAVFRSGEERARRGSSALWVPAGDAACGCPRLLPGRRYLLLGGGPGAAAGGAG 540
Query: 569 ----GIVADKSSLVIQWRDTWARRLRKFQQREKKGKCKKA 604
G++A + SLV+ WRD W RRLR+ Q+RE++G+C A
Sbjct: 541 GRGPGLIAARGSLVLPWRDAWTRRLRRLQRRERRGRCSAA 580
>gi|145309326 laminin, gamma 1 precursor [Homo sapiens]
Length = 1609
Score = 443 bits (1140), Expect = e-124
Identities = 219/453 (48%), Positives = 298/453 (65%), Gaps = 30/453 (6%)
Query: 5 VWEALAALAAVACLVGAVRGGPGLSMFAGQAAQPDPCSDENGHPRRCIPDFVNAAFGKDV 64
+W LA LAA A A QAA D C+DE G P+RC+P+FVNAAF V
Sbjct: 17 LWPVLAVLAAAAAAGCA------------QAAM-DECTDEGGRPQRCMPEFVNAAFNVTV 63
Query: 65 RVSSTCGRPPARYCVVSERGEERL-RSCHLCNASDPKKAHPPAFLTDLNNPHNLTCWQSE 123
++TCG PP YCV + G + +SCHLC+A P H AFLTD NN + T WQS+
Sbjct: 64 VATNTCGTPPEEYCV--QTGVTGVTKSCHLCDAGQPHLQHGAAFLTDYNNQADTTWWQSQ 121
Query: 124 NYL---QFPHNVTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQ 180
L Q+P ++ LTL LGK F++TYV L+F + RPES AIYK W+P+Q+YS
Sbjct: 122 TMLAGVQYPSSINLTLHLGKAFDITYVRLKFHTSRPESFAIYKRTREDGPWIPYQYYSGS 181
Query: 181 CRKMYNRPHRAPI-TKQNEQEAVCTDSHTDMRPLSGGLIAFSTLDGRPSAHDFDNSPVLQ 239
C Y++ +R I T +EQ+A+CTD +D+ PL+GG +AFSTL+GRPSA++FDNSPVLQ
Sbjct: 182 CENTYSKANRGFIRTGGDEQQALCTDEFSDISPLTGGNVAFSTLEGRPSAYNFDNSPVLQ 241
Query: 240 DWVTATDIRVAFSRLHTFGDENEDDSELARDSYFYAVSDLQVGGRCKCNGHAARCVRDRD 299
+WVTATDIRV +RL+TFGDE +D ++ + SY+YA+SD VGGRCKCNGHA+ C+++
Sbjct: 242 EWVTATDIRVTLNRLNTFGDEVFNDPKVLK-SYYYAISDFAVGGRCKCNGHASECMKNEF 300
Query: 300 DSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKL 359
D LVC+C+HNT G +C++C PF DRPW+RATA A+EC+ C+CN ++ C F+ ELY+
Sbjct: 301 DKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCNGRSQECYFDPELYRS 360
Query: 360 SGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQT 419
+G GG C NC+ NT G HC C+E ++R + + +AC +C C PVG+ C+ +
Sbjct: 361 TGH--GGHCTNCQDNTDGAHCERCRENFFR-----LGNNEACSSCHCSPVGSLSTQCD-S 412
Query: 420 TGQCPCKDGVTGITCNRCAKGYQQ-SRSPIAPC 451
G+C CK GV G C+RC G+ + + PC
Sbjct: 413 YGRCSCKPGVMGDKCDRCQPGFHSLTEAGCRPC 445
Score = 94.4 bits (233), Expect = 3e-19
Identities = 63/215 (29%), Positives = 90/215 (41%), Gaps = 63/215 (29%)
Query: 285 CKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNC- 343
C CNGH+ C ++ VC+CR NTAGP C++C +Y +TA +++C C C
Sbjct: 724 CACNGHSETC---DPETGVCNCRDNTAGPHCEKCSDGYYG----DSTAGTSSDCQPCPCP 776
Query: 344 ------------------------------------------NLHARRCRF-----NMEL 356
N R CR N++
Sbjct: 777 GGSSCAVVPKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQCSDNIDP 836
Query: 357 YKLSG-RKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKA--CKACDCHPVGAAG 413
+ + G CL C +NTAG +C CK+G++ G P+ A CKAC+C+ G
Sbjct: 837 NAVGNCNRLTGECLKCIYNTAGFYCDRCKDGFF---GNPLAPNPADKCKACNCNLYGTMK 893
Query: 414 K--TCNQTTGQCPCKDGVTGITCNRCAKGYQQSRS 446
+ +CN TGQC C VTG C C G+ +S
Sbjct: 894 QQSSCNPVTGQCECLPHVTGQDCGACDPGFYNLQS 928
Score = 89.0 bits (219), Expect = 1e-17
Identities = 49/151 (32%), Positives = 69/151 (45%), Gaps = 24/151 (15%)
Query: 287 CNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLH 346
CN C++ C +NTAG CDRCK + P A++C ACNCNL+
Sbjct: 842 CNRLTGECLK---------CIYNTAGFYCDRCKDGFFGNP---LAPNPADKCKACNCNLY 889
Query: 347 ARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDC 406
+ + S G C C + G+ C C G+Y + + C+ CDC
Sbjct: 890 GTMKQ------QSSCNPVTGQC-ECLPHVTGQDCGACDPGFYN-----LQSGQGCERCDC 937
Query: 407 HPVGAAGKTCNQTTGQCPCKDGVTGITCNRC 437
H +G+ C+ TGQC C+ G+TG C RC
Sbjct: 938 HALGSTNGQCDIRTGQCECQPGITGQHCERC 968
Score = 62.8 bits (151), Expect = 9e-10
Identities = 47/144 (32%), Positives = 57/144 (39%), Gaps = 28/144 (19%)
Query: 304 CDCRHNTAGPECDRCKPFHYDRPWQRATAREA--NECVACNCNLHARRCRFNMELYKLSG 361
C C G C+ C ++R T + CV C CN H+ C
Sbjct: 690 CTCPVGYGGQFCEMCLS-----GYRRETPNLGPYSPCVLCACNGHSETCD---------- 734
Query: 362 RKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAA----GKTCN 417
GVC NCR NTAG HC C +GYY D + C+ C C P G++ KT
Sbjct: 735 -PETGVC-NCRDNTAGPHCEKCSDGYYGDSTAGTS--SDCQPCPC-PGGSSCAVVPKTKE 789
Query: 418 QTTGQCPCKDGVTGITCNRCAKGY 441
CP G TG C C GY
Sbjct: 790 VVCTNCP--TGTTGKRCELCDDGY 811
Score = 42.7 bits (99), Expect = 0.001
Identities = 29/104 (27%), Positives = 44/104 (42%), Gaps = 23/104 (22%)
Query: 304 CDCRHNTAGPECDRCKP-FHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGR 362
C C+ G +CDRC+P FH + EA C C+C+ N+E
Sbjct: 416 CSCKPGVMGDKCDRCQPGFH--------SLTEAG-CRPCSCDPSGSIDECNIET------ 460
Query: 363 KSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDC 406
G C+ C+ N G +C CK G++ ++ + C C C
Sbjct: 461 ---GRCV-CKDNVEGFNCERCKPGFF---NLESSNPRGCTPCFC 497
Score = 40.8 bits (94), Expect = 0.004
Identities = 36/140 (25%), Positives = 54/140 (38%), Gaps = 26/140 (18%)
Query: 268 ARDSYFYAVSDLQVGGRC-KCNGHAARCVRDRDDSLV--CDCRHNTAGPECDRCKPFHYD 324
A D FY +LQ G C +C+ HA + D C+C+ G C+RC+ H+
Sbjct: 918 ACDPGFY---NLQSGQGCERCDCHALGSTNGQCDIRTGQCECQPGITGQHCERCEVNHF- 973
Query: 325 RPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCK 384
C C+C+ +++ K G C CR G C C+
Sbjct: 974 -------GFGPEGCKPCDCHPEGS---LSLQC------KDDGRC-ECREGFVGNRCDQCE 1016
Query: 385 EGYYRDMGKPITHRKACKAC 404
E Y+ + P + C AC
Sbjct: 1017 ENYFYNRSWP--GCQECPAC 1034
>gi|24308065 netrin 5 [Homo sapiens]
Length = 489
Score = 387 bits (995), Expect = e-107
Identities = 213/578 (36%), Positives = 300/578 (51%), Gaps = 111/578 (19%)
Query: 28 LSMFAGQAAQPDPCSDENGHPRRCIPDFVNAAFGKDVRVSSTCGRPPARYCVVSERGEER 87
L + GQA DPC D G P+ C+P A V+++C P A C +S
Sbjct: 7 LLLLLGQATA-DPCYDPQGRPQFCLPPVTQLA-----AVAASC--PQA--CALSPGNH-- 54
Query: 88 LRSCHLCNASDPKKAHPPAFLTDLNNPHNLTCWQSENYLQFPHNVTLTLSLGKKFEVTYV 147
L + CN S LTL+LG F +T V
Sbjct: 55 LGARETCNGS------------------------------------LTLALGGPFLLTSV 78
Query: 148 SLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMYNRPHRAPITKQNEQEAVCTDSH 207
SL+FC+P P ++ + + G W R +++RP
Sbjct: 79 SLRFCTPGPPALILSAAWASGGPW----------RLLWHRP------------------- 109
Query: 208 TDMRPLSGGLIAFSTLDGRPSAHDFDNSPVLQDWVTATDIRVAFSRLHTFGDENEDDSEL 267
A+ G P F ++P + V A+ +RV F
Sbjct: 110 -----------AWPGALGGPERVTFHSTPGPKATVAASHLRVEFG--------------- 143
Query: 268 ARDSYFYAVSDLQVGGRCKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPW 327
A + L+ GRC+C+GHAARC R C CRH+T GP C+ C+P H D PW
Sbjct: 144 --GQAGLAAAGLR--GRCQCHGHAARCAA-RARPPRCHCRHHTTGPGCESCRPSHRDWPW 198
Query: 328 QRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGY 387
+ AT R + C+ C+CN HARRCRFN EL++LSG +SGGVC CRH+TAGRHCHYC+ G+
Sbjct: 199 RPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGF 258
Query: 388 YRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSP 447
+RD +PI R+AC+AC CHP+GA G TCNQT+GQC CK GVTG+TCNRC GYQQSRSP
Sbjct: 259 WRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPGYQQSRSP 318
Query: 448 IAPCIKIPVAPPT--TAASSVEEPEDCDSYCKASKGKLKINMKKYCKKDYAVQIHILKAD 505
PC +IP A T T + C +YC S ++ +++++YC++D+ ++ +L ++
Sbjct: 319 RMPCQRIPEATTTLATTPGAYSSDPQCQNYCNMSDTRVHMSLRRYCQQDHVLRAQVLASE 378
Query: 506 KAGD-WWKFTVNIISVYKQGTSRIRRGDQSLWIRSRDIACKCPKIKPLKKYLLLGNAEDS 564
AG W + V +++VYKQ +RRGDQ W+ D+ C C +++P YLLLG+A
Sbjct: 379 AAGPAWQRLAVRVLAVYKQRAQPVRRGDQDAWVPRADLTCGCLRLQPGTDYLLLGSAVGD 438
Query: 565 PDQSGIVADKSSLVIQWRDTWARRLRKFQQREKKGKCK 602
PD + ++ D+ L + WR WAR L++ QQ E+ G C+
Sbjct: 439 PDPTRLILDRHGLALPWRPRWARPLKRLQQEERAGGCR 476
>gi|110611156 laminin, gamma 3 precursor [Homo sapiens]
Length = 1575
Score = 384 bits (987), Expect = e-106
Identities = 194/433 (44%), Positives = 265/433 (61%), Gaps = 19/433 (4%)
Query: 27 GLSMFAGQAAQPD--PCSDENGHPRRCIPDFVNAAFGKDVRVSSTCGRPPARYCV-VSER 83
GL++ A +AA C D G P+RC+P F NAAFG+ + S TCG PP +C V
Sbjct: 9 GLALLAPRAAGAGMGACYDGAGRPQRCLPVFENAAFGRLAQASHTCGSPPEDFCPHVGAA 68
Query: 84 GEERLRSCHLCNASDPKKAHPPAFLTDLNNPHNLTCWQSENY---LQFPHNVTLTLSLGK 140
G C C+A+DP++ H ++LTD ++ T WQS + +Q+P +V +TL LGK
Sbjct: 69 GAGA--HCQRCDAADPQRHHNASYLTDFHSQDESTWWQSPSMAFGVQYPTSVNITLRLGK 126
Query: 141 KFEVTYVSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMYNRPHRAPITK-QNEQ 199
+E+TYV L+F + RPES AIYK W P+QFYS C+K Y RP + ++E+
Sbjct: 127 AYEITYVRLKFHTSRPESFAIYKRSRADGPWEPYQFYSASCQKTYGRPEGQYLRPGEDER 186
Query: 200 EAVCTDSHTDMRPLSGGLIAFSTLDGRPSAHDFDNSPVLQDWVTATDIRVAFSRLHTFGD 259
A CT +D+ PLSGG +AFSTL+GRPSA++F+ SP LQ+WVT+T++ ++ RL+TFGD
Sbjct: 187 VAFCTSEFSDISPLSGGNVAFSTLEGRPSAYNFEESPGLQEWVTSTELLISLDRLNTFGD 246
Query: 260 ENEDDSELARDSYFYAVSDLQVGGRCKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCK 319
+ D ++ + SY+YAVSD VGGRCKCNGHA+ C D L C C+HNT G +C+RC
Sbjct: 247 DIFKDPKVLQ-SYYYAVSDFSVGGRCKCNGHASECGPDVAGQLACRCQHNTTGTDCERCL 305
Query: 320 PFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRH 379
PF DRPW R TA A+EC+ CNC+ + C F+ EL++ +G GG C +CR +TAG H
Sbjct: 306 PFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGH--GGRCHHCRDHTAGPH 363
Query: 380 CHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAK 439
C C+E +Y R C+ CDC G+ C+ TG C CK VTG C+RC
Sbjct: 364 CERCQENFYH-----WDPRMPCQPCDCQSAGSLHLQCDD-TGTCACKPTVTGWKCDRCLP 417
Query: 440 GYQQ-SRSPIAPC 451
G+ S PC
Sbjct: 418 GFHSLSEGGCRPC 430
Score = 94.0 bits (232), Expect = 4e-19
Identities = 63/210 (30%), Positives = 82/210 (39%), Gaps = 64/210 (30%)
Query: 285 CKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNC- 343
C CN H C ++ +C C H+T GP C+RC P Y P+ A +A++C C C
Sbjct: 707 CTCNQHGT-C---DPNTGICVCSHHTEGPSCERCLPGFYGNPF----AGQADDCQPCPCP 758
Query: 344 ---------------------NLHARRCR-----FNMELYKLSGRKS------------- 364
RRC F + L G
Sbjct: 759 GQSACTTIPESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDP 818
Query: 365 ---------GGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKA--CKACDCHPVGAAG 413
G CL C HNT G HC +C+EG+Y G + R A C C CHP G+
Sbjct: 819 NAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFY---GSALAPRPADKCMPCSCHPQGSVS 875
Query: 414 K--TCNQTTGQCPCKDGVTGITCNRCAKGY 441
+ C+ TGQC C VT C+RC G+
Sbjct: 876 EQMPCDPVTGQCSCLPHVTARDCSRCYPGF 905
Score = 63.2 bits (152), Expect = 7e-10
Identities = 51/200 (25%), Positives = 79/200 (39%), Gaps = 57/200 (28%)
Query: 284 RCKCNGHAARCVRDRDDSL---VCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVA 340
+C+C+G+ D L C HNT G C+ C+ Y R A++C+
Sbjct: 809 QCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYG---SALAPRPADKCMP 865
Query: 341 CNCN-----------------------LHARRCR------FNME---------LYKLSGR 362
C+C+ + AR C F+++ + L +
Sbjct: 866 CSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGSQ 925
Query: 363 KSG-----GVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCN 417
+ G C CR G+ C C+ G++ G I K C+AC C P+GAA C+
Sbjct: 926 EDQCHPKTGQC-TCRPGVTGQACDRCQLGFF---GFSI---KGCRACRCSPLGAASAQCH 978
Query: 418 QTTGQCPCKDGVTGITCNRC 437
+ G C C+ G G C+RC
Sbjct: 979 E-NGTCVCRPGFEGYKCDRC 997
Score = 50.8 bits (120), Expect = 4e-06
Identities = 41/145 (28%), Positives = 54/145 (37%), Gaps = 29/145 (20%)
Query: 303 VCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGR 362
+C C G C+ C P Y R + + CV C CN H C N
Sbjct: 672 ICSCPTGYTGQFCESCAP-GYKREMPQGGPYAS--CVPCTCNQHG-TCDPNT-------- 719
Query: 363 KSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQ 422
G+C+ C H+T G C C G+Y G P A +A DC P G++ T +
Sbjct: 720 ---GICV-CSHHTEGPSCERCLPGFY---GNPF----AGQADDCQPCPCPGQSACTTIPE 768
Query: 423 ------CPCKDGVTGITCNRCAKGY 441
C G G C C G+
Sbjct: 769 SREVVCTHCPPGQRGRRCEVCDDGF 793
Score = 30.4 bits (67), Expect = 4.9
Identities = 13/33 (39%), Positives = 16/33 (48%), Gaps = 3/33 (9%)
Query: 423 CPCKDGVTGITCNRCAKGYQQSR---SPIAPCI 452
C C G TG C CA GY++ P A C+
Sbjct: 673 CSCPTGYTGQFCESCAPGYKREMPQGGPYASCV 705
>gi|93204871 netrin 4 [Homo sapiens]
Length = 628
Score = 297 bits (761), Expect = 2e-80
Identities = 200/651 (30%), Positives = 304/651 (46%), Gaps = 84/651 (12%)
Query: 9 LAALAAVACLVGAVRGGPGLSMFAGQAAQPDPCSDENGHPRRCIPDFVNAAFGKDVRVSS 68
+ + A + L G GLS AG +++ + + C P N A G+ + +
Sbjct: 1 MGSCARLLLLWGCTVVAAGLSGVAGVSSRCE---------KACNPRMGNLALGRKLWADT 51
Query: 69 TCGRPPAR-YCVVSERGEERLRS--CHLCNASDPKKAHPPAFLTDLNNPHNLTCWQSENY 125
TCG+ YC SE + R C CNA+ P AH P+ + D + T WQS
Sbjct: 52 TCGQNATELYCFYSENTDLTCRQPKCDKCNAAYPHLAHLPSAMADSSFRFPRTWWQSAED 111
Query: 126 LQFPHNVTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMY 185
+ H + L L +F T++ + F SPRP +M + +S D+G+TW P+++++T C +
Sbjct: 112 V---HREKIQLDLEAEFYFTHLIVMFKSPRPAAMVLDRSQDFGKTWKPYKYFATNCSATF 168
Query: 186 NRPHRAPITKQNEQEAVCTDSHTDMRPLSGGLIAFSTLDGRPSAHDFDN--SPVLQDWVT 243
+ K+ A+CT ++ P +GG + F L +D +N S +Q+ +
Sbjct: 169 GLED--DVVKKG---AICTSKYSSPFPCTGGEVIFKALS---PPYDTENPYSAKVQEQLK 220
Query: 244 ATDIRVAFSRLHTFGDENEDDSELARDSYFYAVSDLQVGGRCKCNGHAARCVRDRDDSLV 303
T++RV + + + D +E + YA+ D V G C CNGHA +C+ V
Sbjct: 221 ITNLRVQLLKRQSCPCQRNDLNEEPQHFTHYAIYDFIVKGSCFCNGHADQCIPVHGFRPV 280
Query: 304 ------------CDCRHNTAGPECDRCKPFHYDRPWQRATAREA--NECVACNCNLHARR 349
C C+HNTAG C C P + DRPW+ A + NEC C CN HA
Sbjct: 281 KAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADT 340
Query: 350 CRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPV 409
C F++ +++ SG +SGGVC +C+HNT G++C CK G+YRD+ +P + ACK C CHPV
Sbjct: 341 CHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPV 400
Query: 410 GAAGKTCNQTT------GQCPCKDGVTGITCNRCAKGY-------------QQSRSPI-A 449
G+A N T G CPCK GV G C+RC GY S PI
Sbjct: 401 GSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDCAGSCDPITG 460
Query: 450 PCI----------KIP-VAPPTTAASSVEEPEDCDSY--------CKASKGKLKINMKKY 490
CI ++P P + E ED + C+ + L N K +
Sbjct: 461 DCISSHTDIDWYHEVPDFRPVHNKSEPAWEWEDAQGFSALLHSGKCECKEQTLG-NAKAF 519
Query: 491 C--KKDYAVQIHILKADKAGDWWKFTVNIISVYKQGTSRIRRGDQSLWIRS-RDIACKCP 547
C K Y ++I IL A G + V I V K +I RG ++L+ S D C CP
Sbjct: 520 CGMKYSYVLKIKILSAHDKGTHVEVNVKIKKVLKSTKLKIFRGKRTLYPESWTDRGCTCP 579
Query: 548 KIKPLKKYLLLGNAEDSPDQSGIVADKSSLVIQWRDTWARRLRKFQQREKK 598
+ P +YL+ G+ + + ++ + S V W+ + R++ +RE K
Sbjct: 580 ILNPGLEYLVAGHEDIRTGK--LIVNMKSFVQHWKPSLGRKVMDILKRECK 628
>gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens]
Length = 3333
Score = 256 bits (653), Expect = 5e-68
Identities = 150/451 (33%), Positives = 236/451 (52%), Gaps = 50/451 (11%)
Query: 53 PDFVNAAFGKDVRVSSTCG-------RP-PARYCVV----SERGEERL---RSCHLCNAS 97
P + N A + ++TCG RP P YC + + G + C CN+
Sbjct: 49 PTYFNLAEAARIWATATCGERGPGEGRPQPELYCKLVGGPTAPGSGHTIQGQFCDYCNSE 108
Query: 98 DPKKAHPPAFLTDLNNPHNLTCWQS---ENYLQFPHNVTLTLSLGKKFEVTYVSLQFC-S 153
DP+KAHP D + WQS + Q+ + V LTL LG+ F V Y+ ++F S
Sbjct: 109 DPRKAHPVTNAIDGSE----RWWQSPPLSSGTQY-NRVNLTLDLGQLFHVAYILIKFANS 163
Query: 154 PRPESMAIYKSMDYGRTWVPFQFYS---TQCRKMYNRPHRAPITKQNEQEAVCTDSHTDM 210
PRP+ + +S+D+G T+ P+Q+++ C K + R +T+ + + +C ++ +
Sbjct: 164 PRPDLWVLERSVDFGSTYSPWQYFAHSKVDCLKEFGREANMAVTR--DDDVLCVTEYSRI 221
Query: 211 RPLSGGLIAFSTLDGRPSAHDFDNSPVLQDWVTATDIRVAFSRLHTFG----DENEDDSE 266
PL G + S ++GRP A +F S L+++ AT+IR+ F R +T + + D
Sbjct: 222 VPLENGEVVVSLINGRPGAKNFTFSHTLREFTKATNIRLRFLRTNTLLGHLISKAQRDPT 281
Query: 267 LARDSYFYAVSDLQVGGRCKCNGHAARCVRDRDDSLV-CDCRHNTAGPECDRCKPFHYDR 325
+ R Y+Y++ D+ +GG+C CNGHA C + + L C+C+H+T G CDRC + R
Sbjct: 282 VTR-RYYYSIKDISIGGQCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQR 340
Query: 326 PWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKS-------GGVCLNCRHNTAGR 378
W+ A +++EC ACNC+ HA C ++ ++ + + GGVC+NC+HNTAG
Sbjct: 341 RWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGV 400
Query: 379 HCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCA 438
+C C +GYYR G P+ C C C P A G C Q +G+C CK G C +CA
Sbjct: 401 NCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADG--CEQGSGRCHCKPNFHGDNCEKCA 458
Query: 439 KGYQQSRSPIAPCIKIPVAPPTTAASSVEEP 469
GY C++IP+ P +T +S E+P
Sbjct: 459 IGYYN----FPFCLRIPIFPVSTPSS--EDP 483
Score = 104 bits (259), Expect = 3e-22
Identities = 66/192 (34%), Positives = 84/192 (43%), Gaps = 40/192 (20%)
Query: 303 VCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGR 362
+C C AG C C P +Y T R CV CNCN H+ +C+
Sbjct: 1653 ICACPPAYAGDSCQGCSPGYYRDHKGLYTGR----CVPCNCNGHSNQCQ----------- 1697
Query: 363 KSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVG--AAGKTCNQTT 420
G+C+NC+HNTAG HC C+EGYY G + +C+AC C A G N
Sbjct: 1698 DGSGICVNCQHNTAGEHCERCQEGYY---GNAV--HGSCRACPCPHTNSFATGCVVNGGD 1752
Query: 421 GQCPCKDGVTGITCNRCAKGY----QQSRSPIAPCI-----KIPVAPPTTA--------- 462
+C CK G TG C RCA GY Q+ PC ++ P T
Sbjct: 1753 VRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKD 1812
Query: 463 ASSVEEPEDCDS 474
+S EE +DCDS
Sbjct: 1813 SSPAEECDDCDS 1824
Score = 76.6 bits (187), Expect = 6e-14
Identities = 58/228 (25%), Positives = 82/228 (35%), Gaps = 83/228 (36%)
Query: 285 CKCNGHAARCVRDRD----------------DSLVCDCRHNTAGPECDRCKPFHYDRPWQ 328
C C+GHA+ C D D + +C+HNTAG C++C +Y RP+
Sbjct: 356 CNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYY-RPYG 414
Query: 329 RATAREANECVACNC-------------------NLHARRCR------------FNMELY 357
+ C+ C+C N H C + ++
Sbjct: 415 -VPVDAPDGCIPCSCDPEHADGCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIF 473
Query: 358 KLSGRKSG-------------------------GVCLNCRHNTAGRHCHYCKEGYYRDMG 392
+S S G CL CR G C C+ G+Y
Sbjct: 474 PVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCL-CRPGVEGPRCDTCRSGFY---S 529
Query: 393 KPITHRKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKG 440
PI C+AC C +G+ C+ TGQC C+ GVTG C+RC G
Sbjct: 530 FPI-----CQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSG 572
Score = 75.9 bits (185), Expect = 1e-13
Identities = 50/160 (31%), Positives = 68/160 (42%), Gaps = 31/160 (19%)
Query: 285 CKCNGHAARCVRDRDDSLVC-DCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNC 343
C CNGH+ +C +D S +C +C+HNTAG C+RC+ +Y C AC C
Sbjct: 1687 CNCNGHSNQC---QDGSGICVNCQHNTAGEHCERCQEGYYGNAVH-------GSCRACPC 1736
Query: 344 ---NLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKA 400
N A C N G V +C+ G C C GY+ G P +
Sbjct: 1737 PHTNSFATGCVVN----------GGDVRCSCKAGYTGTQCERCAPGYF---GNPQKFGGS 1783
Query: 401 CKACDCHPVGAAGKTCNQTTGQC---PCKDGVTGITCNRC 437
C+ C C+ G G +C+ TG C KD C+ C
Sbjct: 1784 CQPCSCNSNGQLG-SCHPLTGDCINQEPKDSSPAEECDDC 1822
Score = 65.9 bits (159), Expect = 1e-10
Identities = 41/141 (29%), Positives = 53/141 (37%), Gaps = 28/141 (19%)
Query: 304 CDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRK 363
C+CR G CDRC YD P + ++ + N NL +C+ ++E
Sbjct: 555 CECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNLGYCQCKLHVE-------- 606
Query: 364 SGGVCLNCRHNTAGRHCHYCKEGYYR-DMGKPITHRKACKACDCHPVGAAGKT--CNQTT 420
G C CK Y+ D P C C CH G T C Q
Sbjct: 607 -------------GPTCSRCKLLYWNLDKENP----SGCSECKCHKAGTVSGTGECRQGD 649
Query: 421 GQCPCKDGVTGITCNRCAKGY 441
G C CK V G +C+ C GY
Sbjct: 650 GDCHCKSHVGGDSCDTCEDGY 670
Score = 64.3 bits (155), Expect = 3e-10
Identities = 38/137 (27%), Positives = 53/137 (38%), Gaps = 21/137 (15%)
Query: 304 CDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRK 363
C C T P+C+ C+ + + C CNC+ R +E +
Sbjct: 1326 CRCPPRTVRPQCEVCETHSF-------SFHPMAGCEGCNCSR-----RGTIEAAMPECDR 1373
Query: 364 SGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQC 423
G C C+ GR C C G+YR C C+C+ G C+ TG C
Sbjct: 1374 DSGQC-RCKPRITGRQCDRCASGFYRF--------PECVPCNCNRDGTEPGVCDPGTGAC 1424
Query: 424 PCKDGVTGITCNRCAKG 440
CK+ V G CN C +G
Sbjct: 1425 LCKENVEGTECNVCREG 1441
Score = 63.9 bits (154), Expect = 4e-10
Identities = 51/193 (26%), Positives = 69/193 (35%), Gaps = 44/193 (22%)
Query: 285 CKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCN 344
C+C+ A + C C+ N G +C RC HY P C C+C
Sbjct: 1266 CECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFP----------RCKPCSCG 1315
Query: 345 LHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKA-CKA 403
R C + G C C T C C+ + H A C+
Sbjct: 1316 --RRLCE-----------EMTGQC-RCPPRTVRPQCEVCETHSFS------FHPMAGCEG 1355
Query: 404 CDCHPVG---AAGKTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVAPPT 460
C+C G AA C++ +GQC CK +TG C+RCA G+ + P P
Sbjct: 1356 CNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGF----------YRFPECVPC 1405
Query: 461 TAASSVEEPEDCD 473
EP CD
Sbjct: 1406 NCNRDGTEPGVCD 1418
Score = 57.0 bits (136), Expect = 5e-08
Identities = 33/93 (35%), Positives = 39/93 (41%), Gaps = 13/93 (13%)
Query: 356 LYKLSGRKSGGVCLNCRHN-------TAGRHCHYCKEGYYRDMGKPITHRKACKACDCHP 408
L+K S KS NC N TA R C + K C+CHP
Sbjct: 1217 LHKKSMDKSLEFITNCGKNSFYLDPQTASRFCKNSARSLVA------FYHKGALPCECHP 1270
Query: 409 VGAAGKTCNQTTGQCPCKDGVTGITCNRCAKGY 441
GA G C+ GQCPC+ V G C RCA G+
Sbjct: 1271 TGATGPHCSPEGGQCPCQPNVIGRQCTRCATGH 1303
Score = 51.2 bits (121), Expect = 3e-06
Identities = 39/135 (28%), Positives = 50/135 (37%), Gaps = 35/135 (25%)
Query: 282 GGRCKCNGHAARCVRDRD-DSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVA 340
G C G + + D DS C C+ G +CDRC Y P ECV
Sbjct: 1355 GCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFP----------ECVP 1404
Query: 341 CNCNLHARRCRFNMELYKLSGRKSG------GVCLNCRHNTAGRHCHYCKEGYYRDMGKP 394
CNCN G + G G CL C+ N G C+ C+EG +
Sbjct: 1405 CNCNR--------------DGTEPGVCDPGTGACL-CKENVEGTECNVCREGSFH---LD 1446
Query: 395 ITHRKACKACDCHPV 409
+ K C +C C V
Sbjct: 1447 PANLKGCTSCFCFGV 1461
>gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens]
Length = 3277
Score = 256 bits (653), Expect = 5e-68
Identities = 150/451 (33%), Positives = 236/451 (52%), Gaps = 50/451 (11%)
Query: 53 PDFVNAAFGKDVRVSSTCG-------RP-PARYCVV----SERGEERL---RSCHLCNAS 97
P + N A + ++TCG RP P YC + + G + C CN+
Sbjct: 49 PTYFNLAEAARIWATATCGERGPGEGRPQPELYCKLVGGPTAPGSGHTIQGQFCDYCNSE 108
Query: 98 DPKKAHPPAFLTDLNNPHNLTCWQS---ENYLQFPHNVTLTLSLGKKFEVTYVSLQFC-S 153
DP+KAHP D + WQS + Q+ + V LTL LG+ F V Y+ ++F S
Sbjct: 109 DPRKAHPVTNAIDGSE----RWWQSPPLSSGTQY-NRVNLTLDLGQLFHVAYILIKFANS 163
Query: 154 PRPESMAIYKSMDYGRTWVPFQFYS---TQCRKMYNRPHRAPITKQNEQEAVCTDSHTDM 210
PRP+ + +S+D+G T+ P+Q+++ C K + R +T+ + + +C ++ +
Sbjct: 164 PRPDLWVLERSVDFGSTYSPWQYFAHSKVDCLKEFGREANMAVTR--DDDVLCVTEYSRI 221
Query: 211 RPLSGGLIAFSTLDGRPSAHDFDNSPVLQDWVTATDIRVAFSRLHTFG----DENEDDSE 266
PL G + S ++GRP A +F S L+++ AT+IR+ F R +T + + D
Sbjct: 222 VPLENGEVVVSLINGRPGAKNFTFSHTLREFTKATNIRLRFLRTNTLLGHLISKAQRDPT 281
Query: 267 LARDSYFYAVSDLQVGGRCKCNGHAARCVRDRDDSLV-CDCRHNTAGPECDRCKPFHYDR 325
+ R Y+Y++ D+ +GG+C CNGHA C + + L C+C+H+T G CDRC + R
Sbjct: 282 VTR-RYYYSIKDISIGGQCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQR 340
Query: 326 PWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKS-------GGVCLNCRHNTAGR 378
W+ A +++EC ACNC+ HA C ++ ++ + + GGVC+NC+HNTAG
Sbjct: 341 RWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGV 400
Query: 379 HCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCA 438
+C C +GYYR G P+ C C C P A G C Q +G+C CK G C +CA
Sbjct: 401 NCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADG--CEQGSGRCHCKPNFHGDNCEKCA 458
Query: 439 KGYQQSRSPIAPCIKIPVAPPTTAASSVEEP 469
GY C++IP+ P +T +S E+P
Sbjct: 459 IGYYN----FPFCLRIPIFPVSTPSS--EDP 483
Score = 104 bits (259), Expect = 3e-22
Identities = 66/192 (34%), Positives = 84/192 (43%), Gaps = 40/192 (20%)
Query: 303 VCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGR 362
+C C AG C C P +Y T R CV CNCN H+ +C+
Sbjct: 1653 ICACPPAYAGDSCQGCSPGYYRDHKGLYTGR----CVPCNCNGHSNQCQ----------- 1697
Query: 363 KSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVG--AAGKTCNQTT 420
G+C+NC+HNTAG HC C+EGYY G + +C+AC C A G N
Sbjct: 1698 DGSGICVNCQHNTAGEHCERCQEGYY---GNAV--HGSCRACPCPHTNSFATGCVVNGGD 1752
Query: 421 GQCPCKDGVTGITCNRCAKGY----QQSRSPIAPCI-----KIPVAPPTTA--------- 462
+C CK G TG C RCA GY Q+ PC ++ P T
Sbjct: 1753 VRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKD 1812
Query: 463 ASSVEEPEDCDS 474
+S EE +DCDS
Sbjct: 1813 SSPAEECDDCDS 1824
Score = 76.6 bits (187), Expect = 6e-14
Identities = 58/228 (25%), Positives = 82/228 (35%), Gaps = 83/228 (36%)
Query: 285 CKCNGHAARCVRDRD----------------DSLVCDCRHNTAGPECDRCKPFHYDRPWQ 328
C C+GHA+ C D D + +C+HNTAG C++C +Y RP+
Sbjct: 356 CNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYY-RPYG 414
Query: 329 RATAREANECVACNC-------------------NLHARRCR------------FNMELY 357
+ C+ C+C N H C + ++
Sbjct: 415 -VPVDAPDGCIPCSCDPEHADGCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIF 473
Query: 358 KLSGRKSG-------------------------GVCLNCRHNTAGRHCHYCKEGYYRDMG 392
+S S G CL CR G C C+ G+Y
Sbjct: 474 PVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCL-CRPGVEGPRCDTCRSGFY---S 529
Query: 393 KPITHRKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKG 440
PI C+AC C +G+ C+ TGQC C+ GVTG C+RC G
Sbjct: 530 FPI-----CQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSG 572
Score = 75.9 bits (185), Expect = 1e-13
Identities = 50/160 (31%), Positives = 68/160 (42%), Gaps = 31/160 (19%)
Query: 285 CKCNGHAARCVRDRDDSLVC-DCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNC 343
C CNGH+ +C +D S +C +C+HNTAG C+RC+ +Y C AC C
Sbjct: 1687 CNCNGHSNQC---QDGSGICVNCQHNTAGEHCERCQEGYYGNAVH-------GSCRACPC 1736
Query: 344 ---NLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKA 400
N A C N G V +C+ G C C GY+ G P +
Sbjct: 1737 PHTNSFATGCVVN----------GGDVRCSCKAGYTGTQCERCAPGYF---GNPQKFGGS 1783
Query: 401 CKACDCHPVGAAGKTCNQTTGQC---PCKDGVTGITCNRC 437
C+ C C+ G G +C+ TG C KD C+ C
Sbjct: 1784 CQPCSCNSNGQLG-SCHPLTGDCINQEPKDSSPAEECDDC 1822
Score = 65.9 bits (159), Expect = 1e-10
Identities = 41/141 (29%), Positives = 53/141 (37%), Gaps = 28/141 (19%)
Query: 304 CDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRK 363
C+CR G CDRC YD P + ++ + N NL +C+ ++E
Sbjct: 555 CECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNLGYCQCKLHVE-------- 606
Query: 364 SGGVCLNCRHNTAGRHCHYCKEGYYR-DMGKPITHRKACKACDCHPVGAAGKT--CNQTT 420
G C CK Y+ D P C C CH G T C Q
Sbjct: 607 -------------GPTCSRCKLLYWNLDKENP----SGCSECKCHKAGTVSGTGECRQGD 649
Query: 421 GQCPCKDGVTGITCNRCAKGY 441
G C CK V G +C+ C GY
Sbjct: 650 GDCHCKSHVGGDSCDTCEDGY 670
Score = 64.3 bits (155), Expect = 3e-10
Identities = 38/137 (27%), Positives = 53/137 (38%), Gaps = 21/137 (15%)
Query: 304 CDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRK 363
C C T P+C+ C+ + + C CNC+ R +E +
Sbjct: 1326 CRCPPRTVRPQCEVCETHSF-------SFHPMAGCEGCNCSR-----RGTIEAAMPECDR 1373
Query: 364 SGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQC 423
G C C+ GR C C G+YR C C+C+ G C+ TG C
Sbjct: 1374 DSGQC-RCKPRITGRQCDRCASGFYRF--------PECVPCNCNRDGTEPGVCDPGTGAC 1424
Query: 424 PCKDGVTGITCNRCAKG 440
CK+ V G CN C +G
Sbjct: 1425 LCKENVEGTECNVCREG 1441
Score = 63.9 bits (154), Expect = 4e-10
Identities = 51/193 (26%), Positives = 69/193 (35%), Gaps = 44/193 (22%)
Query: 285 CKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCN 344
C+C+ A + C C+ N G +C RC HY P C C+C
Sbjct: 1266 CECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFP----------RCKPCSCG 1315
Query: 345 LHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKA-CKA 403
R C + G C C T C C+ + H A C+
Sbjct: 1316 --RRLCE-----------EMTGQC-RCPPRTVRPQCEVCETHSFS------FHPMAGCEG 1355
Query: 404 CDCHPVG---AAGKTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVAPPT 460
C+C G AA C++ +GQC CK +TG C+RCA G+ + P P
Sbjct: 1356 CNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGF----------YRFPECVPC 1405
Query: 461 TAASSVEEPEDCD 473
EP CD
Sbjct: 1406 NCNRDGTEPGVCD 1418
Score = 57.0 bits (136), Expect = 5e-08
Identities = 33/93 (35%), Positives = 39/93 (41%), Gaps = 13/93 (13%)
Query: 356 LYKLSGRKSGGVCLNCRHN-------TAGRHCHYCKEGYYRDMGKPITHRKACKACDCHP 408
L+K S KS NC N TA R C + K C+CHP
Sbjct: 1217 LHKKSMDKSLEFITNCGKNSFYLDPQTASRFCKNSARSLVA------FYHKGALPCECHP 1270
Query: 409 VGAAGKTCNQTTGQCPCKDGVTGITCNRCAKGY 441
GA G C+ GQCPC+ V G C RCA G+
Sbjct: 1271 TGATGPHCSPEGGQCPCQPNVIGRQCTRCATGH 1303
Score = 51.2 bits (121), Expect = 3e-06
Identities = 39/135 (28%), Positives = 50/135 (37%), Gaps = 35/135 (25%)
Query: 282 GGRCKCNGHAARCVRDRD-DSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVA 340
G C G + + D DS C C+ G +CDRC Y P ECV
Sbjct: 1355 GCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFP----------ECVP 1404
Query: 341 CNCNLHARRCRFNMELYKLSGRKSG------GVCLNCRHNTAGRHCHYCKEGYYRDMGKP 394
CNCN G + G G CL C+ N G C+ C+EG +
Sbjct: 1405 CNCNR--------------DGTEPGVCDPGTGACL-CKENVEGTECNVCREGSFH---LD 1446
Query: 395 ITHRKACKACDCHPV 409
+ K C +C C V
Sbjct: 1447 PANLKGCTSCFCFGV 1461
>gi|167614504 laminin, beta 1 precursor [Homo sapiens]
Length = 1786
Score = 254 bits (650), Expect = 1e-67
Identities = 144/418 (34%), Positives = 220/418 (52%), Gaps = 35/418 (8%)
Query: 51 CIPDFVNAAFGK--DVRVSSTCG-RPPARYCVVSERGEERLRSCHLCNASDP--KKAHPP 105
C P + G+ + V+STCG P YC+VS E++ C +CN+ DP + +P
Sbjct: 35 CYPATGDLLIGRAQKLSVTSTCGLHKPEPYCIVSHLQEDK--KCFICNSQDPYHETLNPD 92
Query: 106 AFLTD----LNNPHNLTCW-QSENYLQFPHNVTLTLSLGKKFEVTYVSLQFCSPRPESMA 160
+ L + P+ L W QSEN ++ NVT+ L L +F T++ + F + RP +M
Sbjct: 93 SHLIENVVTTFAPNRLKIWWQSENGVE---NVTIQLDLEAEFHFTHLIMTFKTFRPAAML 149
Query: 161 IYKSMDYGRTWVPFQFYSTQCRKMYNRPHRAPITKQNEQEAVCTDSHTDMRPLSGGLIAF 220
I +S D+G+TW +++++ C + P+ K ++ +C ++D+ P + G + F
Sbjct: 150 IERSSDFGKTWGVYRYFAYDCEASFPGISTGPMKKVDD--IICDSRYSDIEPSTEGEVIF 207
Query: 221 STLDGRPSAHDFDNSPVLQDWVTATDIRVAFSRLHTFGDENEDDSELARDSYFYAVSDLQ 280
LD D SP +Q+ + T++R+ F +LHT GD D R+ Y+YAV D+
Sbjct: 208 RALDPAFKIED-PYSPRIQNLLKITNLRIKFVKLHTLGDNLLDSRMEIREKYYYAVYDMV 266
Query: 281 VGGRCKCNGHAARCV-----RDRDDSLV---CDCRHNTAGPECDRCKPFHYDRPWQRATA 332
V G C C GHA+ C + + +V C CRHNT G C+ C F++D PW+ A
Sbjct: 267 VRGNCFCYGHASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEG 326
Query: 333 REANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMG 392
R +N C CNCN H+ C F+M +Y +G SGGVC +C+HNT GR+C CK YY+
Sbjct: 327 RNSNACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPE 386
Query: 393 KPITHRKACKACDCHPVGAAGK-TCNQTT--------GQCPCKDGVTGITCNRCAKGY 441
+ I C+ C C P G+ + C+ T GQC CK V G C+ C +G+
Sbjct: 387 RDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGF 444
Score = 94.4 bits (233), Expect = 3e-19
Identities = 60/201 (29%), Positives = 81/201 (40%), Gaps = 32/201 (15%)
Query: 251 FSRLHTFGDENEDDSELARDSYFYAVSDLQVGGRCKCNGHAARCVRDRDDSLVCDCRHNT 310
F R +GD + D +Y V + G C+C+ +C+ C N
Sbjct: 1011 FCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCL----------CLPNV 1060
Query: 311 AGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLN 370
G CDRC P WQ A+ C CNCN + S + G C
Sbjct: 1061 IGQNCDRCAP----NTWQLASG---TGCDPCNCNA--------AHSFGPSCNEFTGQC-Q 1104
Query: 371 CRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQCPCKDGVT 430
C GR C C+E ++ D C+ACDC P G C+Q+TGQC C +GV
Sbjct: 1105 CMPGFGGRTCSECQELFWGDPDVE------CRACDCDPRGIETPQCDQSTGQCVCVEGVE 1158
Query: 431 GITCNRCAKGYQQSRSPIAPC 451
G C++C +GY PC
Sbjct: 1159 GPRCDKCTRGYSGVFPDCTPC 1179
Score = 80.9 bits (198), Expect = 3e-15
Identities = 63/218 (28%), Positives = 80/218 (36%), Gaps = 64/218 (29%)
Query: 284 RCKCNGHAARCVRDRDDSL--------VCD-CRHNTAGPECDRCKPFHYDRPWQRATARE 334
+C CN H+ C D L VCD C+HNT G C++CKPF+Y P R+
Sbjct: 334 KCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHP--ERDIRD 391
Query: 335 ANECVACNCNLHAR---------------------RCRFNME----------LYKLSGRK 363
N C C C+ RC+ N+E Y LS
Sbjct: 392 PNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSED 451
Query: 364 SGGVCLNCRHNTAGR------------HCHYCKE---GYYRDMGKP-----ITHRKACKA 403
G C +C N G HC YCK G + D P C+
Sbjct: 452 PFG-CKSCACNPLGTIPGGNPCDSETGHC-YCKRLVTGQHCDQCLPEHWGLSNDLDGCRP 509
Query: 404 CDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKGY 441
CDC GA +C +GQC C+ + G CN GY
Sbjct: 510 CDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGY 547
Score = 74.3 bits (181), Expect = 3e-13
Identities = 46/152 (30%), Positives = 62/152 (40%), Gaps = 23/152 (15%)
Query: 302 LVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSG 361
L C C G CD C ++ P + C C C H + E
Sbjct: 942 LACVCDPGYIGSRCDDCASGYFGNP-----SEVGGSCQPCQC--HNNIDTTDPEACD--- 991
Query: 362 RKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCN---- 417
K G CL C ++T G HC +C+ GYY D ++ C+ C C+ +G + CN
Sbjct: 992 -KETGRCLKCLYHTEGEHCQFCRFGYYGD-----ALQQDCRKCVCNYLGTVQEHCNGSDC 1045
Query: 418 ---QTTGQCPCKDGVTGITCNRCAKGYQQSRS 446
+ TGQC C V G C+RCA Q S
Sbjct: 1046 QCDKATGQCLCLPNVIGQNCDRCAPNTWQLAS 1077
Score = 70.5 bits (171), Expect = 4e-12
Identities = 50/180 (27%), Positives = 68/180 (37%), Gaps = 38/180 (21%)
Query: 304 CDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRK 363
C C +CDRC P H+ P C C CN HA C
Sbjct: 840 CHCFQGVYARQCDRCLPGHWGFP----------SCQPCQCNGHADDCD-----------P 878
Query: 364 SGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQ- 422
G CLNC+ T G +C C GYY D I C+ C C +G+ ++ Q
Sbjct: 879 VTGECLNCQDYTMGHNCERCLAGYYGD--PIIGSGDHCRPCPCPDGPDSGRQFARSCYQD 936
Query: 423 -------CPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVAPPTTAASSVE--EPEDCD 473
C C G G C+ CA GY + S + + P ++++ +PE CD
Sbjct: 937 PVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQ-----PCQCHNNIDTTDPEACD 991
Score = 62.4 bits (150), Expect = 1e-09
Identities = 31/78 (39%), Positives = 38/78 (48%), Gaps = 7/78 (8%)
Query: 364 SGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQC 423
+GG C CR N GR C+ C G + G CK C+CH G+ CN TGQC
Sbjct: 788 NGGQC-QCRPNVVGRTCNRCAPGTF-GFGP-----SGCKPCECHLQGSVNAFCNPVTGQC 840
Query: 424 PCKDGVTGITCNRCAKGY 441
C GV C+RC G+
Sbjct: 841 HCFQGVYARQCDRCLPGH 858
Score = 50.8 bits (120), Expect = 4e-06
Identities = 19/38 (50%), Positives = 23/38 (60%)
Query: 403 ACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKG 440
AC+C P G+ C+ GQC C+ V G TCNRCA G
Sbjct: 772 ACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPG 809
Score = 42.0 bits (97), Expect = 0.002
Identities = 24/85 (28%), Positives = 37/85 (43%), Gaps = 15/85 (17%)
Query: 304 CDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRK 363
C C+ G CD+C P H+ + + + C C+C+L N + SG+
Sbjct: 479 CYCKRLVTGQHCDQCLPEHW------GLSNDLDGCRPCDCDLGGA---LNNSCFAESGQC 529
Query: 364 SGGVCLNCRHNTAGRHCHYCKEGYY 388
S CR + GR C+ + GYY
Sbjct: 530 S------CRPHMIGRQCNEVEPGYY 548
>gi|21264602 laminin alpha 5 [Homo sapiens]
Length = 3695
Score = 254 bits (650), Expect = 1e-67
Identities = 149/427 (34%), Positives = 223/427 (52%), Gaps = 46/427 (10%)
Query: 53 PDFVNAAFGKDVRVSSTCGRP-PAR---------YC------VVSERGEERLRS--CHLC 94
P + N A G + S+TCG PAR YC V + +R C +C
Sbjct: 47 PPYFNLAEGARIAASATCGEEAPARGSPRPTEDLYCKLVGGPVAGGDPNQTIRGQYCDIC 106
Query: 95 NASDPKKAHPPAFLTDLNNPHNLTCWQS---ENYLQFPHNVTLTLSLGKKFEVTYVSLQF 151
A++ KAHP + D WQS L++ + V +TL LG+ F V YV ++F
Sbjct: 107 TAANSNKAHPASNAIDGTE----RWWQSPPLSRGLEY-NEVNVTLDLGQVFHVAYVLIKF 161
Query: 152 C-SPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMYNRPHRAPITK-QNEQEAVCTDSHTD 209
SPRP+ + +SMD+GRT+ P+QF+++ R R + + + A+CT ++
Sbjct: 162 ANSPRPDLWVLERSMDFGRTYQPWQFFASSKRDCLERFGPQTLERITRDDAAICTTEYSR 221
Query: 210 MRPLSGGLIAFSTLDGRPSAHDFDNSPVLQDWVTATDIRVAFSRL-----HTFGDENEDD 264
+ PL G I S ++GRP A +F SP+L+++ AT++R+ F R H G D
Sbjct: 222 IVPLENGEIVVSLVNGRPGAMNFSYSPLLREFTKATNVRLRFLRTNTLLGHLMGKALRDP 281
Query: 265 SELARDSYFYAVSDLQVGGRCKCNGHAARC-VRDRDDS--LVCDCRHNTAGPECDRCKPF 321
+ R Y+Y++ D+ +GGRC C+GHA C +D D L C C+HNT G CDRC P
Sbjct: 282 TVTRR--YYYSIKDISIGGRCVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPG 339
Query: 322 HYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKS-------GGVCLNCRHN 374
+PW+ ATA ANEC +CNC HA C ++ E+ + +S GGVC++C+H+
Sbjct: 340 FNQQPWKPATANSANECQSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHH 399
Query: 375 TAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITC 434
T G +C C G+YR P+ C+ C+C G TC TG+C C+ +G C
Sbjct: 400 TTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDG-TCEDLTGRCYCRPNFSGERC 458
Query: 435 NRCAKGY 441
+ CA+G+
Sbjct: 459 DVCAEGF 465
Score = 81.3 bits (199), Expect = 2e-15
Identities = 60/199 (30%), Positives = 82/199 (41%), Gaps = 23/199 (11%)
Query: 285 CKCNGHAARCVRDRDDSLVC-DCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNC 343
C+C+GH+ RC+ S VC DC+HNT G C+RC+ + + + CV+C C
Sbjct: 1864 CQCHGHSDRCL---PGSGVCVDCQHNTEGAHCERCQ-----AGFVSSRDDPSAPCVSCPC 1915
Query: 344 NLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKA 403
L F GR CL C+ AG C C G++ G P+ +C+
Sbjct: 1916 PLSVPSNNFAEGCVLRGGRTQ---CL-CKPGYAGASCERCAPGFF---GNPLVLGSSCQP 1968
Query: 404 CDCHPVGAAG---KTCNQTTGQC-PCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVAPP 459
CDC G C+ TG C C TG C CA G+ + C + P
Sbjct: 1969 CDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFYGNALLPGNCTRCDCTPC 2028
Query: 460 TTAASSVEEPEDCDSYCKA 478
T A +P CKA
Sbjct: 2029 GTEAC---DPHSGHCLCKA 2044
Score = 79.7 bits (195), Expect = 7e-15
Identities = 50/151 (33%), Positives = 62/151 (41%), Gaps = 32/151 (21%)
Query: 304 CDCRHNTAGPECDRCK------PFHYDRPWQRATARE----ANECVACNCNL---HARRC 350
C CR N +G CD C P Y P RE A + V C+C+ C
Sbjct: 447 CYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNAC 506
Query: 351 RFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVG 410
R + + G CL C+ N G HC C G+Y C+ C C G
Sbjct: 507 RKDPRV---------GRCL-CKPNFQGTHCELCAPGFYGP---------GCQPCQCSSPG 547
Query: 411 AAGKTCNQTTGQCPCKDGVTGITCNRCAKGY 441
A C+ TGQC C+ G G TC+RCA GY
Sbjct: 548 VADDRCDPDTGQCRCRVGFEGATCDRCAPGY 578
Score = 78.6 bits (192), Expect = 2e-14
Identities = 52/178 (29%), Positives = 75/178 (42%), Gaps = 29/178 (16%)
Query: 299 DDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYK 358
D++ C C+ AGP CDRC+P ++ P C AC C+ L +
Sbjct: 600 DEAGRCLCQPEFAGPHCDRCRPGYHGFP----------NCQACTCDPRGA-------LDQ 642
Query: 359 LSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQ 418
L G +GG+C CR G C C G++ G P +C C C G+ C+
Sbjct: 643 LCG--AGGLC-RCRPGYTGTACQECSPGFH---GFP-----SCVPCHCSAEGSLHAACDP 691
Query: 419 TTGQCPCKDGVTGITCNRCAKG-YQQSRSPIAPCIKIPVAPPTTAASSVEEPEDCDSY 475
+GQC C+ VTG+ C+ C G Y C +AP A + P C ++
Sbjct: 692 RSGQCSCRPRVTGLRCDTCVPGAYNFPYCEAGSCHPAGLAPVDPALPEAQVPCMCRAH 749
Score = 77.8 bits (190), Expect = 3e-14
Identities = 58/199 (29%), Positives = 76/199 (38%), Gaps = 33/199 (16%)
Query: 303 VCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGR 362
+C C + G C C P Y + CV C C+ H+ RC L G
Sbjct: 1830 LCLCPASYRGDSCQECAPGFY----RDVKGLFLGRCVPCQCHGHSDRC--------LPG- 1876
Query: 363 KSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCH---PVGAAGKTCNQT 419
GVC++C+HNT G HC C+ G+ P C +C C P + C
Sbjct: 1877 --SGVCVDCQHNTEGAHCERCQAGFVSSRDDP---SAPCVSCPCPLSVPSNNFAEGCVLR 1931
Query: 420 TG--QCPCKDGVTGITCNRCAKGYQQS----RSPIAPCIKIPVAPPTTAASSVEEPEDCD 473
G QC CK G G +C RCA G+ + S PC P S DCD
Sbjct: 1932 GGRTQCLCKPGYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFS------DCD 1985
Query: 474 SYCKASKGKLKINMKKYCK 492
A +G L+ C+
Sbjct: 1986 PLTGACRGCLRHTTGPRCE 2004
Score = 75.9 bits (185), Expect = 1e-13
Identities = 56/181 (30%), Positives = 72/181 (39%), Gaps = 43/181 (23%)
Query: 282 GGRCKCNGHA-----ARCV---------RDRD------DSLV--CDCRHNTAGPECDRCK 319
GG+C C+ H +RC R D D L C C T P+C C+
Sbjct: 1454 GGQCPCHAHVIGRDCSRCATGYWGFPNCRPCDCGARLCDELTGQCICPPRTIPPDCLLCQ 1513
Query: 320 PFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRH 379
P Q C CNC+ + EL + G C CR N GR
Sbjct: 1514 P-------QTFGCHPLVGCEECNCSGPGIQ-----ELTDPTCDTDSGQC-KCRPNVTGRR 1560
Query: 380 CHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAK 439
C C G++ G P C+ CDCH G A C+ TGQC CK+ V G C++C+
Sbjct: 1561 CDTCSPGFH---GYP-----RCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQCSL 1612
Query: 440 G 440
G
Sbjct: 1613 G 1613
Score = 73.9 bits (180), Expect = 4e-13
Identities = 51/167 (30%), Positives = 66/167 (39%), Gaps = 30/167 (17%)
Query: 285 CKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCN 344
C+C+ R D+ C CR G CDRC P ++ P C C C+
Sbjct: 541 CQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPL----------CQLCGCS 590
Query: 345 LHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKAC 404
G G CL C+ AG HC C+ GY+ G P C+AC
Sbjct: 591 PAGT---------LPEGCDEAGRCL-CQPEFAGPHCDRCRPGYH---GFP-----NCQAC 632
Query: 405 DCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPC 451
C P GA + C G C C+ G TG C C+ G+ S + PC
Sbjct: 633 TCDPRGALDQLCG-AGGLCRCRPGYTGTACQECSPGFHGFPSCV-PC 677
Score = 70.9 bits (172), Expect = 3e-12
Identities = 41/142 (28%), Positives = 61/142 (42%), Gaps = 23/142 (16%)
Query: 304 CDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSG-- 361
C CR + GP CDRCKP + + C C+C+L L G
Sbjct: 744 CMCRAHVEGPSCDRCKPGFWG-----LSPSNPEGCTRCSCDLRGT----------LGGVA 788
Query: 362 --RKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQT 419
+ G C C+ + G+ C CK+G++ G C++C C GA G++C
Sbjct: 789 ECQPGTGQCF-CKPHVCGQACASCKDGFF---GLDQADYFGCRSCRCDIGGALGQSCEPR 844
Query: 420 TGQCPCKDGVTGITCNRCAKGY 441
TG C C+ G TC+ A+ +
Sbjct: 845 TGVCRCRPNTQGPTCSEPARDH 866
Score = 69.7 bits (169), Expect = 7e-12
Identities = 49/162 (30%), Positives = 63/162 (38%), Gaps = 29/162 (17%)
Query: 285 CKCNGHAARCVRDRD-DSLVCDCR---HNTAGPECDRCKPFHYDRPWQRATAREANECVA 340
C C+G+ + D D L CR +T GP C+ C P Y A C
Sbjct: 1969 CDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFY------GNALLPGNCTR 2022
Query: 341 CNCN-LHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRK 399
C+C C G CL C+ GR C C+EG++ G
Sbjct: 2023 CDCTPCGTEACD-----------PHSGHCL-CKAGVTGRRCDRCQEGHFGFDGCG----- 2065
Query: 400 ACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKGY 441
C+ C C P A G C+ +GQC C+ G G C CA GY
Sbjct: 2066 GCRPCACGPA-AEGSECHPQSGQCHCRPGTMGPQCRECAPGY 2106
Score = 61.2 bits (147), Expect = 3e-09
Identities = 42/163 (25%), Positives = 61/163 (37%), Gaps = 52/163 (31%)
Query: 287 CNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYD-------RPWQRATAREANECV 339
C+ H+ C+ C+ G CDRC+ H+ RP A E +EC
Sbjct: 2033 CDPHSGHCL----------CKAGVTGRRCDRCQEGHFGFDGCGGCRPCACGPAAEGSEC- 2081
Query: 340 ACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRK 399
G C +CR T G C C GY+ G P +
Sbjct: 2082 ----------------------HPQSGQC-HCRPGTMGPQCRECAPGYW---GLP---EQ 2112
Query: 400 ACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKGYQ 442
C+ C C G C+ TG+C C G++G C+ C++ +Q
Sbjct: 2113 GCRRCQC-----PGGRCDPHTGRCNCPPGLSGERCDTCSQQHQ 2150
Score = 55.1 bits (131), Expect = 2e-07
Identities = 22/45 (48%), Positives = 25/45 (55%)
Query: 397 HRKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKGY 441
+ + C CH VGA G TC GQCPC V G C+RCA GY
Sbjct: 1431 YNNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGY 1475
Score = 52.8 bits (125), Expect = 9e-07
Identities = 47/178 (26%), Positives = 64/178 (35%), Gaps = 39/178 (21%)
Query: 304 CDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRK 363
C C + G +C RC ++ P C C+C AR C R
Sbjct: 1457 CPCHAHVIGRDCSRCATGYWGFP----------NCRPCDCG--ARLCDELTGQCICPPRT 1504
Query: 364 SGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGA---AGKTCNQTT 420
CL C+ T G CH P+ C+ C+C G TC+ +
Sbjct: 1505 IPPDCLLCQPQTFG--CH------------PLV---GCEECNCSGPGIQELTDPTCDTDS 1547
Query: 421 GQCPCKDGVTGITCNRCAKGYQ-QSRSPIAPCIKIPVAPPTTAASSVEEPEDCDSYCK 477
GQC C+ VTG C+ C+ G+ R C + AP V +P YCK
Sbjct: 1548 GQCKCRPNVTGRRCDTCSPGFHGYPRCRPCDCHEAGTAP------GVCDPLTGQCYCK 1599
Score = 33.9 bits (76), Expect = 0.44
Identities = 24/79 (30%), Positives = 32/79 (40%), Gaps = 15/79 (18%)
Query: 404 CDCHPVGAAGKTCNQTTG---QCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVAPPT 460
C CH A + T QC C+ G TC+RC G+ Q P P T
Sbjct: 300 CVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQ----------PWKPAT 349
Query: 461 TAASSVEEPEDCDSYCKAS 479
A+S E + C+ Y A+
Sbjct: 350 --ANSANECQSCNCYGHAT 366
>gi|38788416 laminin, alpha 1 precursor [Homo sapiens]
Length = 3075
Score = 248 bits (634), Expect = 9e-66
Identities = 167/520 (32%), Positives = 255/520 (49%), Gaps = 66/520 (12%)
Query: 22 VRGGPGLSMFAGQAAQPDPCSDENGHPRRCIPDFVNAAFGKDVRVSSTCG-RPPARYCVV 80
+RGG L + AAQ C R P +N A + ++TCG + P +C +
Sbjct: 1 MRGGVLLVLLLCVAAQ---CRQ-----RGLFPAILNLASNAHISTNATCGEKGPEMFCKL 52
Query: 81 SERGEER-LRS--CHLC--NASDPKKAHPPAFLTDLNNPHNLTCWQS---ENYLQFPHNV 132
E R +R+ C +C N+++P++ HP + D N WQS +N ++ H V
Sbjct: 53 VEHVPGRPVRNPQCRICDGNSANPRERHPISHAIDGTN----NWWQSPSIQNGREY-HWV 107
Query: 133 TLTLSLGKKFEVTYVSLQFCS-PRPESMAIYKSMDYGRTWVPFQFYS---TQCRKMYN-R 187
T+TL L + F+V YV ++ + PRP + + +S+D G T+ P+Q+Y+ ++C YN
Sbjct: 108 TITLDLRQVFQVAYVIIKAANAPRPGNWILERSLD-GTTFSPWQYYAVSDSECLSRYNIT 166
Query: 188 PHRAPITKQNEQEAVCTDSHTDMRPLSGGLIAFSTLDGRPSAHDFDNSPVLQDWVTATDI 247
P R P T + + E +CT ++ + PL G I S ++GRPSA D SP L ++ +A I
Sbjct: 167 PRRGPPTYRADDEVICTSYYSRLVPLEHGEIHTSLINGRPSADDL--SPKLLEFTSARYI 224
Query: 248 RVAFSRLHTFGD--------ENEDDSELARDSYFYAVSDLQVGGRCKCNGHAARCVRDRD 299
R+ R+ T E ++ + Y+Y++ D+ VGG C C GHA+ C D
Sbjct: 225 RLRLQRIRTLNADLMTLSHREPKELDPIVTRRYYYSIKDISVGGMCICYGHASSCPWDET 284
Query: 300 DS-LVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYK 358
L C C HNT G C+RC P ++ +PW+ T N C ACNC+ A+ C ++ + K
Sbjct: 285 TKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAK 344
Query: 359 ------LSGR-KSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGA 411
+G+ + GGVC+NC NT G +C C +GYYR + C+ C+C PVG+
Sbjct: 345 QKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGS 404
Query: 412 AGKTC-----------NQTTGQCPCKDGVTGITCNRCAKGYQQ-------SRSPIAPCIK 453
C + GQCPCK+G TG C+RC GY+ +P+
Sbjct: 405 LSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYPTCVSCGCNPVGSASD 464
Query: 454 IPVAPPTTAASSVEEPEDCDSYCKASKGKLKINMKKYCKK 493
P P +V E + CD CK LK + C +
Sbjct: 465 EPCTGPCVCKENV-EGKACDR-CKPGFYNLKEKNPRGCSE 502
Score = 94.4 bits (233), Expect = 3e-19
Identities = 65/226 (28%), Positives = 84/226 (37%), Gaps = 66/226 (29%)
Query: 271 SYFYAVSDLQVGG---RCKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPW 327
S +Y V + GG C+C+GHAA C + C HNT G C++C P Y P
Sbjct: 725 SGYYRVDGILFGGICQPCECHGHAAEC---NVHGVCIACAHNTTGVHCEQCLPGFYGEP- 780
Query: 328 QRATAREANECVACNCNLHARRCRFNMELYKLSGRK------------------------ 363
R T +C C C L F+ + G +
Sbjct: 781 SRGT---PGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYG 837
Query: 364 --------------SGGV--------------CLNCRHNTAGRHCHYCKEGYYRDMGKPI 395
SG V CL C NT G HC C +G+Y D
Sbjct: 838 NPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCADGFYGD----A 893
Query: 396 THRKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKGY 441
K C+AC+CH G+ C+ TG C CK VTG C++C GY
Sbjct: 894 VTAKNCRACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGY 939
Score = 90.5 bits (223), Expect = 4e-18
Identities = 50/153 (32%), Positives = 71/153 (46%), Gaps = 13/153 (8%)
Query: 285 CKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCN 344
C CN H+ C D + +C NTAG CD C +Y + A++C C C
Sbjct: 1403 CSCNNHSDTC--DPNTGKCLNCGDNTAGDHCDVCTSGYYGK-----VTGSASDCALCACP 1455
Query: 345 LHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKAC 404
H+ F+ L G C C G+HC C YY G P T +C+ C
Sbjct: 1456 -HSPPASFSPTCV-LEGDHDFR-CDACLLGYEGKHCERCSSSYY---GNPQTPGGSCQKC 1509
Query: 405 DCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRC 437
DC+P G+ C++T+GQC C+ G +G+ C+ C
Sbjct: 1510 DCNPHGSVHGDCDRTSGQCVCRLGASGLRCDEC 1542
Score = 70.5 bits (171), Expect = 4e-12
Identities = 49/175 (28%), Positives = 67/175 (38%), Gaps = 27/175 (15%)
Query: 270 DSYFYAVSDLQVGGRCK-CNGHAARCVRDR-DDSLVCDCRHNTAGPECDRCKPFHYDRPW 327
D + L G C+ CN A V D D C C AG CDRC Y
Sbjct: 933 DQCLHGYYGLDSGHGCRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCDRCAHGFY---- 988
Query: 328 QRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGY 387
A + C C+C C G C+ C +T G C C++G+
Sbjct: 989 ----AYQDGSCTPCDCPHTQNTCD-----------PETGECV-CPPHTQGVKCEECEDGH 1032
Query: 388 YRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKGYQ 442
+ C+AC+C VG+ C+ TG C CK G C++C+ GY+
Sbjct: 1033 WG-----YDAEVGCQACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGYR 1082
Score = 67.4 bits (163), Expect = 4e-11
Identities = 52/182 (28%), Positives = 70/182 (38%), Gaps = 36/182 (19%)
Query: 304 CDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRK 363
C+C G C+ C +Y + C C C+ HA C +
Sbjct: 709 CECPQGYTGTSCESCLSGYY----RVDGILFGGICQPCECHGHAAECNVH---------- 754
Query: 364 SGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKA-CKACDCHPVGAAGK----TCNQ 418
GVC+ C HNT G HC C G+Y G+P C+ C C P+ A TC+
Sbjct: 755 --GVCIACAHNTTGVHCEQCLPGFY---GEPSRGTPGDCQPCAC-PLTIASNNFSPTCHL 808
Query: 419 TTGQ---CP-CKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVAPPTTAASSVEEPE--DC 472
G C C G +G C RCA GY + P + P + +V+ E C
Sbjct: 809 NDGDEVVCDWCAPGYSGAWCERCADGYYGN-----PTVPGESCVPCDCSGNVDPSEAGHC 863
Query: 473 DS 474
DS
Sbjct: 864 DS 865
Score = 65.5 bits (158), Expect = 1e-10
Identities = 46/149 (30%), Positives = 58/149 (38%), Gaps = 39/149 (26%)
Query: 304 CDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHA---RRCRFNMELYKLS 360
C C +T G +C+ C+ H+ + C ACNC+L RC
Sbjct: 1014 CVCPPHTQGVKCEECEDGHWGYDAEVG-------CQACNCSLVGSTHHRCDVVT------ 1060
Query: 361 GRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCN--- 417
G C C+ GR C C GY RD C CDC G +G CN
Sbjct: 1061 -----GHC-QCKSKFGGRACDQCSLGY-RDFPD-------CVPCDCDLRGTSGDACNLEQ 1106
Query: 418 ------QTTGQCPCKDGVTGITCNRCAKG 440
+ TG CPCK+ V G CN C +G
Sbjct: 1107 GLCGCVEETGACPCKENVFGPQCNECREG 1135
Score = 42.4 bits (98), Expect = 0.001
Identities = 31/114 (27%), Positives = 46/114 (40%), Gaps = 15/114 (13%)
Query: 278 DLQVGGRCKCNGHAARCVRDRDDSLV--CDCRHNTAGPECDRCKPFHYDRPWQRATAREA 335
D +VG + CN R D + C C+ G CD+C + D P
Sbjct: 1036 DAEVGCQA-CNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGYRDFP--------- 1085
Query: 336 NECVACNCNLHARRC-RFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYY 388
+CV C+C+L N+E + G C C+ N G C+ C+EG +
Sbjct: 1086 -DCVPCDCDLRGTSGDACNLEQGLCGCVEETGAC-PCKENVFGPQCNECREGTF 1137
Score = 32.3 bits (72), Expect = 1.3
Identities = 13/40 (32%), Positives = 18/40 (45%), Gaps = 10/40 (25%)
Query: 423 CPCKDGVTGITCNRCAKGYQQSRSP----------IAPCI 452
C C G G +C CA GY + + P +APC+
Sbjct: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCV 1401
Score = 31.2 bits (69), Expect = 2.9
Identities = 14/39 (35%), Positives = 18/39 (46%)
Query: 284 RCKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFH 322
+C CN H + S C CR +G CD C+P H
Sbjct: 1508 KCDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDECEPRH 1546
>gi|119703755 laminin, beta 2 precursor [Homo sapiens]
Length = 1798
Score = 247 bits (630), Expect = 3e-65
Identities = 160/486 (32%), Positives = 238/486 (48%), Gaps = 39/486 (8%)
Query: 22 VRGGPGLSMFAGQAAQPDPCSDENGHPR-RCIPDFVNAAFGKDVRV--SSTCG-RPPARY 77
+R G LS+ A AQ P D G R C P + G+ R+ SSTCG P Y
Sbjct: 18 LRLGLLLSVLAATLAQA-PAPDVPGCSRGSCYPATGDLLVGRADRLTASSTCGLNGPQPY 76
Query: 78 CVVSERGEERLRSCHLCNASDPKKAHPPAFLTDLNN-------PHNLTCWQSENYLQFPH 130
C+VS +E+ C LC++ P A + N WQSEN +
Sbjct: 77 CIVSHLQDEK--KCFLCDSRRPFSARDNPHSHRIQNVVTSFAPQRRAAWWQSENGIPA-- 132
Query: 131 NVTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMYNRPHR 190
VT+ L L +F T++ + F + RP +M + +S D+GRTW ++++S C +
Sbjct: 133 -VTIQLDLEAEFHFTHLIMTFKTFRPAAMLVERSADFGRTWHVYRYFSYDCGADFPGVPL 191
Query: 191 APITKQNEQEAVCTDSHTDMRPLSGGLIAFSTLDGRPSAHDFDNSPVLQDWVTATDIRVA 250
AP ++ + VC ++++ P + G + + LD D +S + Q+ + T++RV
Sbjct: 192 AP--PRHWDDVVCESRYSEIEPSTEGEVIYRVLDPAIPIPDPYSSRI-QNLLKITNLRVN 248
Query: 251 FSRLHTFGDENEDDSELARDSYFYAVSDLQVGGRCKCNGHAARCVRD-----RDDSLV-- 303
+RLHT GD D R+ Y+YA+ +L V G C C GHA+ C + +V
Sbjct: 249 LTRLHTLGDNLLDPRREIREKYYYALYELVVRGNCFCYGHASECAPAPGAPAHAEGMVHG 308
Query: 304 -CDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGR 362
C C+HNT G C++C+ F+ D PW+ A ++ C C C+ H C F+M +Y SG
Sbjct: 309 ACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASGN 368
Query: 363 KSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAA-GKTCNQ--- 418
SGGVC C+HNTAGRHC C+ +YRD K + C++CDC P+G+ G C+
Sbjct: 369 VSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDD 428
Query: 419 -----TTGQCPCKDGVTGITCNRCAKG-YQQSRSPIAPCIKIPV-APPTTAASSVEEPED 471
+GQC CK+ V G C +C G + S S C + A T S+ +P
Sbjct: 429 PALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNS 488
Query: 472 CDSYCK 477
YCK
Sbjct: 489 GSCYCK 494
Score = 84.7 bits (208), Expect = 2e-16
Identities = 53/171 (30%), Positives = 71/171 (41%), Gaps = 37/171 (21%)
Query: 282 GGRCK---------------CNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRP 326
GGRC+ C+ H +C+R C H+T GP C CKP + +
Sbjct: 980 GGRCQLCECSGNIDPMDPDACDPHTGQCLR---------CLHHTEGPHCAHCKPGFHGQ- 1029
Query: 327 WQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEG 386
AR++ C C CNL + + S G C C N G C C
Sbjct: 1030 ----AARQS--CHRCTCNLLGTNPQQCPSPDQCHCDPSSGQC-PCLPNVQGPSCDRCAPN 1082
Query: 387 YYRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRC 437
++ +T C+ C CHP A G TCN+ TGQC C+ G G TC+ C
Sbjct: 1083 FWN-----LTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSEC 1128
Score = 84.0 bits (206), Expect = 4e-16
Identities = 51/183 (27%), Positives = 75/183 (40%), Gaps = 25/183 (13%)
Query: 273 FYAVSDLQVGGRCK---C-------NGHAARCVRDR-DDSLVCDCRHNTAGPECDRCKPF 321
F+ L GG+C+ C A C +D +VC CR G C+ C P
Sbjct: 912 FHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPG 971
Query: 322 HYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCH 381
H+ P +R C C C+ + + + G CL C H+T G HC
Sbjct: 972 HFGDP-----SRPGGRCQLCECSGNID------PMDPDACDPHTGQCLRCLHHTEGPHCA 1020
Query: 382 YCKEGYYRDMGKPITHRKACKACDCHPVGAAGKT---CNQTTGQCPCKDGVTGITCNRCA 438
+CK G++ + HR C +P C+ ++GQCPC V G +C+RCA
Sbjct: 1021 HCKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCA 1080
Query: 439 KGY 441
+
Sbjct: 1081 PNF 1083
Score = 80.9 bits (198), Expect = 3e-15
Identities = 47/148 (31%), Positives = 65/148 (43%), Gaps = 22/148 (14%)
Query: 304 CDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRK 363
C C N GP CDRC P ++ + C C C H R R + +
Sbjct: 1065 CPCLPNVQGPSCDRCAPNFWN-------LTSGHGCQPCAC--HPSRARGP------TCNE 1109
Query: 364 SGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQC 423
G C +CR GR C C+E ++ D G C ACDC G C++ TG C
Sbjct: 1110 FTGQC-HCRAGFGGRTCSECQELHWGDPGLQ------CHACDCDSRGIDTPQCHRFTGHC 1162
Query: 424 PCKDGVTGITCNRCAKGYQQSRSPIAPC 451
C+ GV+G+ C++CA+G+ PC
Sbjct: 1163 SCRPGVSGVRCDQCARGFSGIFPACHPC 1190
Score = 75.1 bits (183), Expect = 2e-13
Identities = 49/166 (29%), Positives = 65/166 (39%), Gaps = 33/166 (19%)
Query: 285 CKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCN 344
C+C+ A S C CR G CDRC+ + P C C CN
Sbjct: 831 CQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFP----------SCRPCVCN 880
Query: 345 LHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKAC 404
HA C + G CL CR +T G HC C G++ D P + C+ C
Sbjct: 881 GHADECNTHT-----------GACLGCRDHTGGEHCERCIAGFHGDPRLP--YGGQCRPC 927
Query: 405 DCHPVGAAGK-----TCNQTTGQ----CPCKDGVTGITCNRCAKGY 441
C P G + +C+Q C C+ G TG+ C CA G+
Sbjct: 928 PC-PEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGH 972
Score = 70.5 bits (171), Expect = 4e-12
Identities = 55/222 (24%), Positives = 81/222 (36%), Gaps = 72/222 (32%)
Query: 284 RCKCNGHAARCVRDRDDSL--------VCD-CRHNTAGPECDRCKPFHYDRPWQRATARE 334
+C+C+GH C D L VCD C+HNTAG C+ C+PF Y P + R+
Sbjct: 346 KCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTK--DLRD 403
Query: 335 ANECVACNCN---------------------------------LHARRCRFNMELYKLSG 361
C +C+C+ ++CR +S
Sbjct: 404 PAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISD 463
Query: 362 R---------------------KSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRK- 399
R + G C C+ GR C C G++ ++H
Sbjct: 464 RLGCRRCQCNARGTVPGSTPCDPNSGSCY-CKRLVTGRGCDRCLPGHWG-----LSHDLL 517
Query: 400 ACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKGY 441
C+ CDC GA C++ TGQC C+ + G C + GY
Sbjct: 518 GCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGY 559
Score = 67.4 bits (163), Expect = 4e-11
Identities = 35/88 (39%), Positives = 44/88 (50%), Gaps = 8/88 (9%)
Query: 365 GGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQCP 424
GG CL C+ GR C C GYY G T C+AC C GA C +T+GQC
Sbjct: 799 GGQCL-CKPGVVGRRCDLCAPGYY---GFGPT---GCQACQCSHEGALSSLCEKTSGQCL 851
Query: 425 CKDGVTGITCNRCAKGYQQSRSPIAPCI 452
C+ G G+ C+RC +G Q PC+
Sbjct: 852 CRTGAFGLRCDRCQRG-QWGFPSCRPCV 878
Score = 48.5 bits (114), Expect = 2e-05
Identities = 19/38 (50%), Positives = 22/38 (57%)
Query: 404 CDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKGY 441
C C+P G+ CN GQC CK GV G C+ CA GY
Sbjct: 783 CQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGY 820
Score = 43.9 bits (102), Expect = 4e-04
Identities = 34/127 (26%), Positives = 52/127 (40%), Gaps = 24/127 (18%)
Query: 269 RDSYF-YAVSDLQVGGRCKCN--GHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDR 325
RD +F ++SD RC+CN G +S C C+ G CDRC P H+
Sbjct: 453 RDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHW-- 510
Query: 326 PWQRATAREANECVACNCNLHAR---RCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHY 382
+ + C C+C++ +C + G C +CR + GR C
Sbjct: 511 ----GLSHDLLGCRPCDCDVGGALDPQCD-----------EGTGQC-HCRQHMVGRRCEQ 554
Query: 383 CKEGYYR 389
+ GY+R
Sbjct: 555 VQPGYFR 561
Score = 37.7 bits (86), Expect = 0.031
Identities = 25/103 (24%), Positives = 39/103 (37%), Gaps = 17/103 (16%)
Query: 285 CKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCN 344
C C+ AR + + C CR G C C+ H+ P +C AC+C+
Sbjct: 1095 CACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDP--------GLQCHACDCD 1146
Query: 345 LHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGY 387
R + ++ +G S CR +G C C G+
Sbjct: 1147 ---SRGIDTPQCHRFTGHCS------CRPGVSGVRCDQCARGF 1180
>gi|143770880 laminin, beta 4 [Homo sapiens]
Length = 1761
Score = 246 bits (628), Expect = 4e-65
Identities = 146/424 (34%), Positives = 219/424 (51%), Gaps = 51/424 (12%)
Query: 51 CIPDFVNAAFGKDVRV--SSTCGRPPA-RYCVVSE-RGEERLRSCHLCNASDPKKAHPPA 106
C P + G++ ++ SSTCG A +YC++S GE++ C +C++ P +
Sbjct: 28 CHPTTGDLLVGRNTQLMASSTCGLSRAQKYCILSYLEGEQK---CFICDSRFPYDPYDQP 84
Query: 107 FLTDLNN-------PHNLTCWQSENYLQFPHNVTLTLSLGKKFEVTYVSLQFCSPRPESM 159
+ N WQSEN L +V++ L L F +++ L F + RP +M
Sbjct: 85 NSHTIENVIVSFEPDREKKWWQSENGLD---HVSIRLDLEALFRFSHLILTFKTFRPAAM 141
Query: 160 AIYKSMDYGRTWVPFQFYSTQCRKMYNRPHRAPITKQNEQEAVCTDSHTDMRPLSGGLIA 219
+ +S DYG W F++++ C + P+ Q + VC ++D+ P +GG +
Sbjct: 142 LVERSTDYGHNWKVFKYFAKDCATSF--PNITSGQAQGVGDIVCDSKYSDIEPSTGGEVV 199
Query: 220 FSTLDGRPSAHDFDN--SPVLQDWVTATDIRVAFSRLHTFGD----ENEDDSELARDSYF 273
LD + + +N SP +QD VT T++R+ F++LHT GD ++DS D Y+
Sbjct: 200 LKVLD---PSFEIENPYSPYIQDLVTLTNLRINFTKLHTLGDALLGRRQNDS---LDKYY 253
Query: 274 YAVSDLQVGGRCKCNGHAARC---VRDRDDSLV--------CDCRHNTAGPECDRCKPFH 322
YA+ ++ V G C CNGHA+ C + R D C C+HNT GP C+RCK F
Sbjct: 254 YALYEMIVRGSCFCNGHASECRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERCKDFF 313
Query: 323 YDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHY 382
D PW+ A + N C +C+CN H+ RC F+M Y SG SGGVC +C+HNT G+HC
Sbjct: 314 QDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDR 373
Query: 383 CKEGYYRDMGKPITHRKACKACDCHPVGA-AGKTC--------NQTTGQCPCKDGVTGIT 433
C+ +YRD K I+ AC C+C P G +G C GQC CK+ V G
Sbjct: 374 CRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAK 433
Query: 434 CNRC 437
C++C
Sbjct: 434 CDQC 437
Score = 89.4 bits (220), Expect = 9e-18
Identities = 54/176 (30%), Positives = 74/176 (42%), Gaps = 26/176 (14%)
Query: 302 LVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSG 361
++C+C G +C C Y P R + C ACN N+ S
Sbjct: 936 VICNCLQGYTGTQCGECSTGFYGNP--RISGAPCQPC-ACNNNIDVTDPE--------SC 984
Query: 362 RKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCH---------PVGAA 412
+ G CL C HNT G +C CK G+Y G + + C+ C CH P G
Sbjct: 985 SRVTGECLRCLHNTQGANCQLCKPGHY---GSALN--QTCRRCSCHASGVSPMECPPGGG 1039
Query: 413 GKTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVAPPTTAASSVEE 468
C+ TG CPC VTG+ C+RCA GY + P C P T+ +S ++
Sbjct: 1040 ACLCDPVTGACPCLPNVTGLACDRCADGY-WNLVPGRGCQSCDCDPRTSQSSHCDQ 1094
Score = 87.4 bits (215), Expect = 3e-17
Identities = 67/260 (25%), Positives = 92/260 (35%), Gaps = 89/260 (34%)
Query: 255 HTFGDENEDDSELARDSYFYAVSDLQVGG--RCKCNGHAARCVRDRDDSL--------VC 304
+T G E + +D+ + +DLQ C CN H++RC D L VC
Sbjct: 300 NTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVC 359
Query: 305 -DCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRK 363
DC+HNT G CDRC+P Y P + T + C+ C C+ G
Sbjct: 360 EDCQHNTEGQHCDRCRPLFYRDPLK--TISDPYACIPCECDP--------------DGTI 403
Query: 364 SGGVCLN--------------CRHNTAGRHCHYCKEGYYR-------------------- 389
SGG+C++ C+ N G C CK +Y
Sbjct: 404 SGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSL 463
Query: 390 -------DMGKPI---------------------THRKACKACDCHPVGAAGKTCNQTTG 421
D G+ + H C CDC GA C+ G
Sbjct: 464 PFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNG 523
Query: 422 QCPCKDGVTGITCNRCAKGY 441
QC C+ VTG +C+ A GY
Sbjct: 524 QCECRPHVTGRSCSEPAPGY 543
Score = 77.4 bits (189), Expect = 3e-14
Identities = 49/170 (28%), Positives = 68/170 (40%), Gaps = 32/170 (18%)
Query: 282 GGRCKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVAC 341
GG C C+ C C N G CDRC D W R C +C
Sbjct: 1038 GGACLCDPVTG----------ACPCLPNVTGLACDRCA----DGYWNLVPGRG---CQSC 1080
Query: 342 NCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKAC 401
+C+ R + +L+G+ C+ G+ C C+E YY D C
Sbjct: 1081 DCD---PRTSQSSHCDQLTGQ------CPCKLGYGGKRCSECQENYYGDPPG------RC 1125
Query: 402 KACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPC 451
CDC+ G C+ TG C C++GV+G C+RCA+G+ Q C
Sbjct: 1126 IPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRCARGHSQEFPTCLQC 1175
Score = 68.6 bits (166), Expect = 2e-11
Identities = 33/77 (42%), Positives = 39/77 (50%), Gaps = 7/77 (9%)
Query: 365 GGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQCP 424
GG C C+ GR C C G Y D+G C C CHP G+ C+Q TGQCP
Sbjct: 785 GGQC-QCKPLVVGRCCDRCSTGSY-DLG-----HHGCHPCHCHPQGSKDTVCDQVTGQCP 837
Query: 425 CKDGVTGITCNRCAKGY 441
C V+G C+RC GY
Sbjct: 838 CHGEVSGRRCDRCLAGY 854
Score = 66.2 bits (160), Expect = 8e-11
Identities = 50/180 (27%), Positives = 68/180 (37%), Gaps = 42/180 (23%)
Query: 304 CDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRK 363
C C +G CDRC ++ P C C CN A C
Sbjct: 836 CPCHGEVSGRRCDRCLAGYFGFP----------SCHPCPCNRFAELCD-----------P 874
Query: 364 SGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGK----TCNQT 419
G C NC T GR+C C +GYY G P + + C+ C C ++ + +C Q
Sbjct: 875 ETGSCFNCGGFTTGRNCERCIDGYY---GNP-SSGQPCRPCLCPDDPSSNQYFAHSCYQN 930
Query: 420 TGQ----CPCKDGVTGITCNRCAKG-YQQSRSPIAPCIKIPVAPPTTAASSVE--EPEDC 472
C C G TG C C+ G Y R APC P ++++ +PE C
Sbjct: 931 LWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPC------QPCACNNNIDVTDPESC 984
Score = 52.8 bits (125), Expect = 9e-07
Identities = 25/65 (38%), Positives = 31/65 (47%), Gaps = 1/65 (1%)
Query: 403 ACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKG-YQQSRSPIAPCIKIPVAPPTT 461
AC CHP G+ G +C++ GQC CK V G C+RC+ G Y PC P T
Sbjct: 768 ACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHPCHCHPQGSKDT 827
Query: 462 AASSV 466
V
Sbjct: 828 VCDQV 832
>gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo
sapiens]
Length = 3118
Score = 246 bits (627), Expect = 6e-65
Identities = 158/470 (33%), Positives = 235/470 (50%), Gaps = 54/470 (11%)
Query: 13 AAVACLVGAVRGGPGLSMFAGQAAQPDPCSDENGHPRRCI-PDFVNAAFGKDVRVSSTCG 71
AA L+ + GG G QA +P H +R + P +N A + ++TCG
Sbjct: 4 AAGVLLLLLLSGGLG----GVQAQRPQQQRQSQAHQQRGLFPAVLNLASNALITTNATCG 59
Query: 72 -RPPARYCVVSER--GEE-RLRSCHLCN--ASDPKKAHPPAFLTDLNNPHNLTCWQS--- 122
+ P YC + E G+ R C +CN +S+P + HP D N T WQS
Sbjct: 60 EKGPEMYCKLVEHVPGQPVRNPQCRICNQNSSNPNQRHPITNAIDGKN----TWWQSPSI 115
Query: 123 ENYLQFPHNVTLTLSLGKKFEVTYVSLQFC-SPRPESMAIYKSMDYGRTWVPFQFYS--- 178
+N +++ H VT+TL L + F++ YV ++ SPRP + + +S+D + P+Q+++
Sbjct: 116 KNGIEY-HYVTITLDLQQVFQIAYVIVKAANSPRPGNWILERSLD-DVEYKPWQYHAVTD 173
Query: 179 TQCRKMYN-RPHRAPITKQNEQEAVCTDSHTDMRPLSGGLIAFSTLDGRPSAHDFDNSPV 237
T+C +YN P P + + E +CT ++ + PL G I S ++GRPSA D SP
Sbjct: 174 TECLTLYNIYPRTGPPSYAKDDEVICTSFYSKIHPLENGEIHISLINGRPSADD--PSPE 231
Query: 238 LQDWVTATDIRVAFSRLHTFG---------DENEDDSELARDSYFYAVSDLQVGGRCKCN 288
L ++ +A IR+ F R+ T D E D + R Y+Y+V D+ VGG C C
Sbjct: 232 LLEFTSARYIRLRFQRIRTLNADLMMFAHKDPREIDPIVTR-RYYYSVKDISVGGMCICY 290
Query: 289 GHAARCVRD-RDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHA 347
GHA C D + C+C HNT G CD+C P + +PW+ T EC ACNC+ A
Sbjct: 291 GHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKA 350
Query: 348 RRC-------RFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKA 400
C R N+ L GGVC+NC NTAG +C C +G++R G + +
Sbjct: 351 EECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRP 410
Query: 401 CKACDCHPVGAAGKTC---------NQTTGQCPCKDGVTGITCNRCAKGY 441
C+ C C P+G+ + C G C CK G G++C+RCA+GY
Sbjct: 411 CQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGY 460
Score = 89.7 bits (221), Expect = 7e-18
Identities = 52/169 (30%), Positives = 75/169 (44%), Gaps = 22/169 (13%)
Query: 288 NGHAARCVRDRDDSLVCD-CRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLH 346
N + C DR L+CD C GP C+RC ++ +P + C C CN
Sbjct: 816 NNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQP-----SVPGGSCQPCQCN-- 868
Query: 347 ARRCRFNMELYKLSGR--KSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKAC 404
N++ + + G G CL C+ T GR+C C +GY+ D K C+ C
Sbjct: 869 -----DNLD-FSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDA----VDAKNCQPC 918
Query: 405 DCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKGY--QQSRSPIAPC 451
C+ G+ + C+ TGQC C+ V G C++C G QS PC
Sbjct: 919 RCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPC 967
Score = 87.8 bits (216), Expect = 3e-17
Identities = 47/153 (30%), Positives = 71/153 (46%), Gaps = 12/153 (7%)
Query: 285 CKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCN 344
C+CNGH++ C D + S+ +C+H+TAG C+RC +Y N+C C C
Sbjct: 1420 CQCNGHSSLC--DPETSICQNCQHHTAGDFCERCALGYYG-----IVKGLPNDCQQCACP 1472
Query: 345 LHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKAC 404
L + F+ ++ C C G++C C GY G P +C+ C
Sbjct: 1473 LISSSNNFSPSC--VAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNP---GGSCQEC 1527
Query: 405 DCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRC 437
+C P G+ C+ TG C C+ G TG C+ C
Sbjct: 1528 ECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGC 1560
Score = 84.0 bits (206), Expect = 4e-16
Identities = 66/260 (25%), Positives = 94/260 (36%), Gaps = 54/260 (20%)
Query: 266 ELARDSYFYAVSDLQVGGRCKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDR 325
EL D YF D + C+CN + + C+CR N G CD+CK +
Sbjct: 899 ELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFG- 957
Query: 326 PWQRATAREANECVACNCNLHARR---CRFNMELYKLSGRKSGGVCLNCRH--------- 373
+ A CV CNCN + C + + + G +G C C H
Sbjct: 958 ------LQSARGCVPCNCNSFGSKSFDCEESGQCWCQPG-VTGKKCDRCAHGYFNFQEGG 1010
Query: 374 ------------------------NTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPV 409
NT G C C + G IT CKAC+C V
Sbjct: 1011 CTACECSHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTW---GHSIT--TGCKACNCSTV 1065
Query: 410 GAAGKTCNQTTGQCPCKDGVTGITCNRCAKG-YQQSRSPIAPCIKIPVAPPTTAASSVEE 468
G+ CN TGQC C +G C C++G + R + C P T A + E
Sbjct: 1066 GSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCF----LPGTDATTCDSE 1121
Query: 469 PEDCDSYCKASKGKLKINMK 488
+ C + + K+N++
Sbjct: 1122 TKKCSCSDQTGQCTCKVNVE 1141
Score = 68.6 bits (166), Expect = 2e-11
Identities = 44/152 (28%), Positives = 57/152 (37%), Gaps = 26/152 (17%)
Query: 304 CDCRHNTAGPECDRCKPFHY---DRPWQRATAREANECVACNCNLHARRCRFNMELYKLS 360
CDC +G C+ C P Y +P R CV C CN H+ C
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCD--------- 1430
Query: 361 GRKSGGVCLNCRHNTAGRHCHYCKEGYYRDM-GKPITHRKACKACDCHPVGAAGKTCNQT 419
+C NC+H+TAG C C GYY + G P C+ C C + ++
Sbjct: 1431 --PETSICQNCQHHTAGDFCERCALGYYGIVKGLP----NDCQQCACPLISSSNNFSPSC 1484
Query: 420 TGQ-------CPCKDGVTGITCNRCAKGYQQS 444
+ C G G C RCA GY S
Sbjct: 1485 VAEGLDDYRCTACPRGYEGQYCERCAPGYTGS 1516
Score = 64.3 bits (155), Expect = 3e-10
Identities = 44/149 (29%), Positives = 55/149 (36%), Gaps = 39/149 (26%)
Query: 304 CDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHAR---RCRFNMELYKLS 360
C C NT G +C +C P W + C ACNC+ +C N
Sbjct: 1030 CICPPNTIGEKCSKCAP----NTWGHSIT---TGCKACNCSTVGSLDFQCNVNT------ 1076
Query: 361 GRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTT 420
G C NC +G C C G++ + C CDC G TC+ T
Sbjct: 1077 -----GQC-NCHPKFSGAKCTECSRGHW--------NYPRCNLCDCFLPGTDATTCDSET 1122
Query: 421 ---------GQCPCKDGVTGITCNRCAKG 440
GQC CK V GI C+RC G
Sbjct: 1123 KKCSCSDQTGQCTCKVNVEGIHCDRCRPG 1151
Score = 60.1 bits (144), Expect = 6e-09
Identities = 45/152 (29%), Positives = 58/152 (38%), Gaps = 36/152 (23%)
Query: 303 VCDCRHNTAGPECDRCKPFHYDRPWQRATAREANE------CVACNCNLHARRCRFNMEL 356
VC C G C+ C P H R N C C C HA C
Sbjct: 723 VCQCPPGYTGSSCESCWPRH----------RRVNGTIFGGICEPCQCFGHAESCD----- 767
Query: 357 YKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCH---PVGAAG 413
G CLNC+ +T G +C C G+Y + K + + C+ C C P
Sbjct: 768 ------DVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTS--EDCQPCACPLNIPSNNFS 819
Query: 414 KTC--NQTTGQC--PCKDGVTGITCNRCAKGY 441
TC +++ G C G TG C RCA+GY
Sbjct: 820 PTCHLDRSLGLICDGCPVGYTGPRCERCAEGY 851
Score = 42.4 bits (98), Expect = 0.001
Identities = 42/172 (24%), Positives = 62/172 (36%), Gaps = 39/172 (22%)
Query: 304 CDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNL---HARRCRFNMELYKLS 360
C+C +G +C C H++ P C C+C L A C + E K S
Sbjct: 1079 CNCHPKFSGAKCTECSRGHWNYP----------RCNLCDCFLPGTDATTC--DSETKKCS 1126
Query: 361 GRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTT 420
G C C+ N G HC C+ G + K +P+G + C TT
Sbjct: 1127 CSDQTGQC-TCKVNVEGIHCDRCRPGKFGLDAK-------------NPLGCSSCYCFGTT 1172
Query: 421 GQCPCKDGV--TGITCNRCAKGYQQSRSPIAPCIKIPVAPPTTAASSVEEPE 470
QC G+ T +T ++ I P + + TT + PE
Sbjct: 1173 TQCSEAKGLIRTWVTL--------KAEQTILPLVDEALQHTTTKGIVFQHPE 1216
Score = 39.7 bits (91), Expect = 0.008
Identities = 30/119 (25%), Positives = 43/119 (36%), Gaps = 24/119 (20%)
Query: 304 CDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRK 363
C C+ G CDRC + P +C ACNC+ L +
Sbjct: 442 CHCKTGFGGVSCDRCARGYTGYP----------DCKACNCS----------GLGSKNEDP 481
Query: 364 SGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQ 422
G C+ C+ N G C CK G++ + K C C C V ++ T G+
Sbjct: 482 CFGPCI-CKENVEGGDCSRCKSGFF---NLQEDNWKGCDECFCSGVSNRCQSSYWTYGK 536
Score = 35.0 bits (79), Expect = 0.20
Identities = 19/57 (33%), Positives = 26/57 (45%), Gaps = 9/57 (15%)
Query: 285 CKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVAC 341
C+C+ + + V + C CR G +CD CK +H ARE ECV C
Sbjct: 1527 CECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGCKHWH---------AREGWECVFC 1574
Score = 31.6 bits (70), Expect = 2.2
Identities = 16/57 (28%), Positives = 24/57 (42%), Gaps = 6/57 (10%)
Query: 287 CNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNC 343
C+ +C D + C C+ N G CDRC+P + A+ C +C C
Sbjct: 1118 CDSETKKCSCS-DQTGQCTCKVNVEGIHCDRCRPGKFG-----LDAKNPLGCSSCYC 1168
>gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo
sapiens]
Length = 3122
Score = 246 bits (627), Expect = 6e-65
Identities = 158/470 (33%), Positives = 235/470 (50%), Gaps = 54/470 (11%)
Query: 13 AAVACLVGAVRGGPGLSMFAGQAAQPDPCSDENGHPRRCI-PDFVNAAFGKDVRVSSTCG 71
AA L+ + GG G QA +P H +R + P +N A + ++TCG
Sbjct: 4 AAGVLLLLLLSGGLG----GVQAQRPQQQRQSQAHQQRGLFPAVLNLASNALITTNATCG 59
Query: 72 -RPPARYCVVSER--GEE-RLRSCHLCN--ASDPKKAHPPAFLTDLNNPHNLTCWQS--- 122
+ P YC + E G+ R C +CN +S+P + HP D N T WQS
Sbjct: 60 EKGPEMYCKLVEHVPGQPVRNPQCRICNQNSSNPNQRHPITNAIDGKN----TWWQSPSI 115
Query: 123 ENYLQFPHNVTLTLSLGKKFEVTYVSLQFC-SPRPESMAIYKSMDYGRTWVPFQFYS--- 178
+N +++ H VT+TL L + F++ YV ++ SPRP + + +S+D + P+Q+++
Sbjct: 116 KNGIEY-HYVTITLDLQQVFQIAYVIVKAANSPRPGNWILERSLD-DVEYKPWQYHAVTD 173
Query: 179 TQCRKMYN-RPHRAPITKQNEQEAVCTDSHTDMRPLSGGLIAFSTLDGRPSAHDFDNSPV 237
T+C +YN P P + + E +CT ++ + PL G I S ++GRPSA D SP
Sbjct: 174 TECLTLYNIYPRTGPPSYAKDDEVICTSFYSKIHPLENGEIHISLINGRPSADD--PSPE 231
Query: 238 LQDWVTATDIRVAFSRLHTFG---------DENEDDSELARDSYFYAVSDLQVGGRCKCN 288
L ++ +A IR+ F R+ T D E D + R Y+Y+V D+ VGG C C
Sbjct: 232 LLEFTSARYIRLRFQRIRTLNADLMMFAHKDPREIDPIVTR-RYYYSVKDISVGGMCICY 290
Query: 289 GHAARCVRD-RDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHA 347
GHA C D + C+C HNT G CD+C P + +PW+ T EC ACNC+ A
Sbjct: 291 GHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKA 350
Query: 348 RRC-------RFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKA 400
C R N+ L GGVC+NC NTAG +C C +G++R G + +
Sbjct: 351 EECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRP 410
Query: 401 CKACDCHPVGAAGKTC---------NQTTGQCPCKDGVTGITCNRCAKGY 441
C+ C C P+G+ + C G C CK G G++C+RCA+GY
Sbjct: 411 CQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGY 460
Score = 89.7 bits (221), Expect = 7e-18
Identities = 52/169 (30%), Positives = 75/169 (44%), Gaps = 22/169 (13%)
Query: 288 NGHAARCVRDRDDSLVCD-CRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLH 346
N + C DR L+CD C GP C+RC ++ +P + C C CN
Sbjct: 816 NNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQP-----SVPGGSCQPCQCN-- 868
Query: 347 ARRCRFNMELYKLSGR--KSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKAC 404
N++ + + G G CL C+ T GR+C C +GY+ D K C+ C
Sbjct: 869 -----DNLD-FSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDA----VDAKNCQPC 918
Query: 405 DCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKGY--QQSRSPIAPC 451
C+ G+ + C+ TGQC C+ V G C++C G QS PC
Sbjct: 919 RCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPC 967
Score = 87.8 bits (216), Expect = 3e-17
Identities = 47/153 (30%), Positives = 71/153 (46%), Gaps = 12/153 (7%)
Query: 285 CKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCN 344
C+CNGH++ C D + S+ +C+H+TAG C+RC +Y N+C C C
Sbjct: 1420 CQCNGHSSLC--DPETSICQNCQHHTAGDFCERCALGYYG-----IVKGLPNDCQQCACP 1472
Query: 345 LHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKAC 404
L + F+ ++ C C G++C C GY G P +C+ C
Sbjct: 1473 LISSSNNFSPSC--VAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNP---GGSCQEC 1527
Query: 405 DCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRC 437
+C P G+ C+ TG C C+ G TG C+ C
Sbjct: 1528 ECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGC 1560
Score = 84.0 bits (206), Expect = 4e-16
Identities = 66/260 (25%), Positives = 94/260 (36%), Gaps = 54/260 (20%)
Query: 266 ELARDSYFYAVSDLQVGGRCKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDR 325
EL D YF D + C+CN + + C+CR N G CD+CK +
Sbjct: 899 ELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFG- 957
Query: 326 PWQRATAREANECVACNCNLHARR---CRFNMELYKLSGRKSGGVCLNCRH--------- 373
+ A CV CNCN + C + + + G +G C C H
Sbjct: 958 ------LQSARGCVPCNCNSFGSKSFDCEESGQCWCQPG-VTGKKCDRCAHGYFNFQEGG 1010
Query: 374 ------------------------NTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPV 409
NT G C C + G IT CKAC+C V
Sbjct: 1011 CTACECSHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTW---GHSIT--TGCKACNCSTV 1065
Query: 410 GAAGKTCNQTTGQCPCKDGVTGITCNRCAKG-YQQSRSPIAPCIKIPVAPPTTAASSVEE 468
G+ CN TGQC C +G C C++G + R + C P T A + E
Sbjct: 1066 GSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCF----LPGTDATTCDSE 1121
Query: 469 PEDCDSYCKASKGKLKINMK 488
+ C + + K+N++
Sbjct: 1122 TKKCSCSDQTGQCTCKVNVE 1141
Score = 68.6 bits (166), Expect = 2e-11
Identities = 44/152 (28%), Positives = 57/152 (37%), Gaps = 26/152 (17%)
Query: 304 CDCRHNTAGPECDRCKPFHY---DRPWQRATAREANECVACNCNLHARRCRFNMELYKLS 360
CDC +G C+ C P Y +P R CV C CN H+ C
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCD--------- 1430
Query: 361 GRKSGGVCLNCRHNTAGRHCHYCKEGYYRDM-GKPITHRKACKACDCHPVGAAGKTCNQT 419
+C NC+H+TAG C C GYY + G P C+ C C + ++
Sbjct: 1431 --PETSICQNCQHHTAGDFCERCALGYYGIVKGLP----NDCQQCACPLISSSNNFSPSC 1484
Query: 420 TGQ-------CPCKDGVTGITCNRCAKGYQQS 444
+ C G G C RCA GY S
Sbjct: 1485 VAEGLDDYRCTACPRGYEGQYCERCAPGYTGS 1516
Score = 64.3 bits (155), Expect = 3e-10
Identities = 44/149 (29%), Positives = 55/149 (36%), Gaps = 39/149 (26%)
Query: 304 CDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHAR---RCRFNMELYKLS 360
C C NT G +C +C P W + C ACNC+ +C N
Sbjct: 1030 CICPPNTIGEKCSKCAP----NTWGHSIT---TGCKACNCSTVGSLDFQCNVNT------ 1076
Query: 361 GRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTT 420
G C NC +G C C G++ + C CDC G TC+ T
Sbjct: 1077 -----GQC-NCHPKFSGAKCTECSRGHW--------NYPRCNLCDCFLPGTDATTCDSET 1122
Query: 421 ---------GQCPCKDGVTGITCNRCAKG 440
GQC CK V GI C+RC G
Sbjct: 1123 KKCSCSDQTGQCTCKVNVEGIHCDRCRPG 1151
Score = 60.1 bits (144), Expect = 6e-09
Identities = 45/152 (29%), Positives = 58/152 (38%), Gaps = 36/152 (23%)
Query: 303 VCDCRHNTAGPECDRCKPFHYDRPWQRATAREANE------CVACNCNLHARRCRFNMEL 356
VC C G C+ C P H R N C C C HA C
Sbjct: 723 VCQCPPGYTGSSCESCWPRH----------RRVNGTIFGGICEPCQCFGHAESCD----- 767
Query: 357 YKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCH---PVGAAG 413
G CLNC+ +T G +C C G+Y + K + + C+ C C P
Sbjct: 768 ------DVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTS--EDCQPCACPLNIPSNNFS 819
Query: 414 KTC--NQTTGQC--PCKDGVTGITCNRCAKGY 441
TC +++ G C G TG C RCA+GY
Sbjct: 820 PTCHLDRSLGLICDGCPVGYTGPRCERCAEGY 851
Score = 42.4 bits (98), Expect = 0.001
Identities = 42/172 (24%), Positives = 62/172 (36%), Gaps = 39/172 (22%)
Query: 304 CDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNL---HARRCRFNMELYKLS 360
C+C +G +C C H++ P C C+C L A C + E K S
Sbjct: 1079 CNCHPKFSGAKCTECSRGHWNYP----------RCNLCDCFLPGTDATTC--DSETKKCS 1126
Query: 361 GRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTT 420
G C C+ N G HC C+ G + K +P+G + C TT
Sbjct: 1127 CSDQTGQC-TCKVNVEGIHCDRCRPGKFGLDAK-------------NPLGCSSCYCFGTT 1172
Query: 421 GQCPCKDGV--TGITCNRCAKGYQQSRSPIAPCIKIPVAPPTTAASSVEEPE 470
QC G+ T +T ++ I P + + TT + PE
Sbjct: 1173 TQCSEAKGLIRTWVTL--------KAEQTILPLVDEALQHTTTKGIVFQHPE 1216
Score = 39.7 bits (91), Expect = 0.008
Identities = 30/119 (25%), Positives = 43/119 (36%), Gaps = 24/119 (20%)
Query: 304 CDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRK 363
C C+ G CDRC + P +C ACNC+ L +
Sbjct: 442 CHCKTGFGGVSCDRCARGYTGYP----------DCKACNCS----------GLGSKNEDP 481
Query: 364 SGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQ 422
G C+ C+ N G C CK G++ + K C C C V ++ T G+
Sbjct: 482 CFGPCI-CKENVEGGDCSRCKSGFF---NLQEDNWKGCDECFCSGVSNRCQSSYWTYGK 536
Score = 35.0 bits (79), Expect = 0.20
Identities = 19/57 (33%), Positives = 26/57 (45%), Gaps = 9/57 (15%)
Query: 285 CKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVAC 341
C+C+ + + V + C CR G +CD CK +H ARE ECV C
Sbjct: 1527 CECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGCKHWH---------AREGWECVFC 1574
Score = 31.6 bits (70), Expect = 2.2
Identities = 16/57 (28%), Positives = 24/57 (42%), Gaps = 6/57 (10%)
Query: 287 CNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNC 343
C+ +C D + C C+ N G CDRC+P + A+ C +C C
Sbjct: 1118 CDSETKKCSCS-DQTGQCTCKVNVEGIHCDRCRPGKFG-----LDAKNPLGCSSCYC 1168
>gi|164414431 netrin G1 isoform 1 [Homo sapiens]
Length = 539
Score = 241 bits (616), Expect = 1e-63
Identities = 136/401 (33%), Positives = 203/401 (50%), Gaps = 45/401 (11%)
Query: 69 TCGRPPARYCVVSERGEERLRSCHLCNASDPKKAHPPAFLTDLNNPHNLTCWQSENYLQF 128
TCG PP +C + + C+AS P+ AHPP + D H T WQS + ++
Sbjct: 71 TCGDPPETFCAMGNP----YMCNNECDASTPELAHPPELMFDFEGRHPSTFWQSATWKEY 126
Query: 129 PH--NVTLTLSLGKKFEVT-YVSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMY 185
P V +TLS K E+T + + F S RP+ M + KS+DYGRTW P+Q+Y+T C +
Sbjct: 127 PKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAF 186
Query: 186 NRPHRA--PITKQNEQEAVCTDSHTDMRPLSGGLIAFSTLD-----GRPSAHDF------ 232
+ ++ +++ E +CT+ ++ + +I F D P +
Sbjct: 187 HMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQ 246
Query: 233 -DNSPVLQDWVTATDIRVAFSRLHTFGDENEDDSELARDSYFYAVSDLQVGGRCKCNGHA 291
D + L+D+ T TD+R+ R G+ D+ LAR YFYA+SD++V GRCKCN HA
Sbjct: 247 LDTTKKLRDFFTVTDLRIRLLR-PAVGEIFVDELHLAR--YFYAISDIKVRGRCKCNLHA 303
Query: 292 ARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRAT-----AREANECVA------ 340
CV D + L C+C HNT GP+C +CK + RPW + AN C+
Sbjct: 304 TVCVYD-NSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIG 362
Query: 341 -CNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRK 399
C C H+ RC + L + +C++C+HNT G+HC C+ GY+R+ +
Sbjct: 363 NCECFGHSNRCSYIDLLNTV-------ICVSCKHNTRGQHCELCRLGYFRNASAQLDDEN 415
Query: 400 ACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKG 440
C C C+P+G+ CN +G C CK G TG C+ C G
Sbjct: 416 VCIECYCNPLGSIHDRCN-GSGFCECKTGTTGPKCDECLPG 455
Score = 32.7 bits (73), Expect = 0.99
Identities = 20/78 (25%), Positives = 28/78 (35%), Gaps = 4/78 (5%)
Query: 398 RKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVA 457
R CK C+ H T C C+ TG C +C K YQ + IP
Sbjct: 294 RGRCK-CNLHATVCVYDNSKLT---CECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKG 349
Query: 458 PPTTAASSVEEPEDCDSY 475
T S+ +C+ +
Sbjct: 350 TANTCIPSISSIGNCECF 367
>gi|62868217 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 223 bits (569), Expect = 3e-58
Identities = 134/411 (32%), Positives = 210/411 (51%), Gaps = 39/411 (9%)
Query: 51 CIPDFVNAAFGKD--VRVSSTCG-RPPARYCVVSERGEERLRSCHLCNASDPKKAHPPAF 107
C P + G+ +R SSTCG P YC ++ GE +++ C C++ P +
Sbjct: 26 CYPPVGDLLVGRTRFLRASSTCGLTKPETYC--TQYGEWQMKCCK-CDSRQPHNYYSHRV 82
Query: 108 LTDLNNPHNLTCWQSENYLQFPHNVTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDY 167
++ + WQS+N + + V+L L L ++F++ V ++F P P M I +S D+
Sbjct: 83 ENVASSSGPMRWWQSQNDV---NPVSLQLDLDRRFQLQEVMMEFQGPMPAGMLIERSSDF 139
Query: 168 GRTWVPFQFYSTQCRKMYNRPHRAPITKQNEQEAVCTDSHTDMRP---LSGGLIAFSTLD 224
G+TW +Q+ + C + R + Q+ Q+ C RP L+GG + + +D
Sbjct: 140 GKTWRVYQYLAADCTSTFPRVRQG--RPQSWQDVRCQS--LPQRPNARLNGGKVQLNLMD 195
Query: 225 ---GRPSAHDFDNSPVLQDWVTATDIRVAFSRLHTFGDENEDDSELARDSYFYAVSDLQV 281
G P+ S +Q+ T++RV F+RL S +YAVS L++
Sbjct: 196 LVSGIPATQ----SQKIQEVGEITNLRVNFTRLAPVPQRGYHPP-----SAYYAVSQLRL 246
Query: 282 GGRCKCNGHAARCVRDRDDSL----------VCDCRHNTAGPECDRCKPFHYDRPWQRAT 331
G C C+GHA RC S VC C+HNTAGP C+RC PF+ +RPW+ A
Sbjct: 247 QGSCFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAE 306
Query: 332 AREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDM 391
++A+EC C+CN H+ C F+ ++ S GGVC NCR +T G++C C+ Y+R+
Sbjct: 307 GQDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNR 366
Query: 392 GKPITHRKACKACDCHPVGAA-GKTCNQTTGQCPCKDGVTGITCNRCAKGY 441
+ ++ C +C+C P GA G C+ TGQC CK+ V G C+ C G+
Sbjct: 367 RPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGF 417
Score = 79.7 bits (195), Expect = 7e-15
Identities = 54/182 (29%), Positives = 81/182 (44%), Gaps = 37/182 (20%)
Query: 284 RCKCNGHAARCVRDR---DDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVA 340
RC CN +R RD ++S C C N GP+CD+C P+H W+ A+ + C
Sbjct: 430 RCDCNILGSR--RDMPCDEESGRCLCLPNVVGPKCDQCAPYH----WKLASGQGCEPCAC 483
Query: 341 CNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHC-----HYCKEGYYRDMGKPI 395
N + +C + G C CR G C C + Y D+
Sbjct: 484 DPHNSLSPQCN-----------QFTGQC-PCREGFGGLMCSAAAIRQCPDRTYGDVAT-- 529
Query: 396 THRKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIA----PC 451
C+ACDC G G C++ +G+C C+ G+TG C++C +GY +R P+ PC
Sbjct: 530 ----GCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGY-CNRYPVCVACHPC 584
Query: 452 IK 453
+
Sbjct: 585 FQ 586
>gi|62868215 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 223 bits (569), Expect = 3e-58
Identities = 134/411 (32%), Positives = 210/411 (51%), Gaps = 39/411 (9%)
Query: 51 CIPDFVNAAFGKD--VRVSSTCG-RPPARYCVVSERGEERLRSCHLCNASDPKKAHPPAF 107
C P + G+ +R SSTCG P YC ++ GE +++ C C++ P +
Sbjct: 26 CYPPVGDLLVGRTRFLRASSTCGLTKPETYC--TQYGEWQMKCCK-CDSRQPHNYYSHRV 82
Query: 108 LTDLNNPHNLTCWQSENYLQFPHNVTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDY 167
++ + WQS+N + + V+L L L ++F++ V ++F P P M I +S D+
Sbjct: 83 ENVASSSGPMRWWQSQNDV---NPVSLQLDLDRRFQLQEVMMEFQGPMPAGMLIERSSDF 139
Query: 168 GRTWVPFQFYSTQCRKMYNRPHRAPITKQNEQEAVCTDSHTDMRP---LSGGLIAFSTLD 224
G+TW +Q+ + C + R + Q+ Q+ C RP L+GG + + +D
Sbjct: 140 GKTWRVYQYLAADCTSTFPRVRQG--RPQSWQDVRCQS--LPQRPNARLNGGKVQLNLMD 195
Query: 225 ---GRPSAHDFDNSPVLQDWVTATDIRVAFSRLHTFGDENEDDSELARDSYFYAVSDLQV 281
G P+ S +Q+ T++RV F+RL S +YAVS L++
Sbjct: 196 LVSGIPATQ----SQKIQEVGEITNLRVNFTRLAPVPQRGYHPP-----SAYYAVSQLRL 246
Query: 282 GGRCKCNGHAARCVRDRDDSL----------VCDCRHNTAGPECDRCKPFHYDRPWQRAT 331
G C C+GHA RC S VC C+HNTAGP C+RC PF+ +RPW+ A
Sbjct: 247 QGSCFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAE 306
Query: 332 AREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDM 391
++A+EC C+CN H+ C F+ ++ S GGVC NCR +T G++C C+ Y+R+
Sbjct: 307 GQDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNR 366
Query: 392 GKPITHRKACKACDCHPVGAA-GKTCNQTTGQCPCKDGVTGITCNRCAKGY 441
+ ++ C +C+C P GA G C+ TGQC CK+ V G C+ C G+
Sbjct: 367 RPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGF 417
Score = 79.7 bits (195), Expect = 7e-15
Identities = 54/182 (29%), Positives = 81/182 (44%), Gaps = 37/182 (20%)
Query: 284 RCKCNGHAARCVRDR---DDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVA 340
RC CN +R RD ++S C C N GP+CD+C P+H W+ A+ + C
Sbjct: 430 RCDCNILGSR--RDMPCDEESGRCLCLPNVVGPKCDQCAPYH----WKLASGQGCEPCAC 483
Query: 341 CNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHC-----HYCKEGYYRDMGKPI 395
N + +C + G C CR G C C + Y D+
Sbjct: 484 DPHNSLSPQCN-----------QFTGQC-PCREGFGGLMCSAAAIRQCPDRTYGDVAT-- 529
Query: 396 THRKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIA----PC 451
C+ACDC G G C++ +G+C C+ G+TG C++C +GY +R P+ PC
Sbjct: 530 ----GCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGY-CNRYPVCVACHPC 584
Query: 452 IK 453
+
Sbjct: 585 FQ 586
>gi|189083719 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 223 bits (569), Expect = 3e-58
Identities = 134/411 (32%), Positives = 210/411 (51%), Gaps = 39/411 (9%)
Query: 51 CIPDFVNAAFGKD--VRVSSTCG-RPPARYCVVSERGEERLRSCHLCNASDPKKAHPPAF 107
C P + G+ +R SSTCG P YC ++ GE +++ C C++ P +
Sbjct: 26 CYPPVGDLLVGRTRFLRASSTCGLTKPETYC--TQYGEWQMKCCK-CDSRQPHNYYSHRV 82
Query: 108 LTDLNNPHNLTCWQSENYLQFPHNVTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDY 167
++ + WQS+N + + V+L L L ++F++ V ++F P P M I +S D+
Sbjct: 83 ENVASSSGPMRWWQSQNDV---NPVSLQLDLDRRFQLQEVMMEFQGPMPAGMLIERSSDF 139
Query: 168 GRTWVPFQFYSTQCRKMYNRPHRAPITKQNEQEAVCTDSHTDMRP---LSGGLIAFSTLD 224
G+TW +Q+ + C + R + Q+ Q+ C RP L+GG + + +D
Sbjct: 140 GKTWRVYQYLAADCTSTFPRVRQG--RPQSWQDVRCQS--LPQRPNARLNGGKVQLNLMD 195
Query: 225 ---GRPSAHDFDNSPVLQDWVTATDIRVAFSRLHTFGDENEDDSELARDSYFYAVSDLQV 281
G P+ S +Q+ T++RV F+RL S +YAVS L++
Sbjct: 196 LVSGIPATQ----SQKIQEVGEITNLRVNFTRLAPVPQRGYHPP-----SAYYAVSQLRL 246
Query: 282 GGRCKCNGHAARCVRDRDDSL----------VCDCRHNTAGPECDRCKPFHYDRPWQRAT 331
G C C+GHA RC S VC C+HNTAGP C+RC PF+ +RPW+ A
Sbjct: 247 QGSCFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAE 306
Query: 332 AREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDM 391
++A+EC C+CN H+ C F+ ++ S GGVC NCR +T G++C C+ Y+R+
Sbjct: 307 GQDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNR 366
Query: 392 GKPITHRKACKACDCHPVGAA-GKTCNQTTGQCPCKDGVTGITCNRCAKGY 441
+ ++ C +C+C P GA G C+ TGQC CK+ V G C+ C G+
Sbjct: 367 RPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGF 417
Score = 79.7 bits (195), Expect = 7e-15
Identities = 54/182 (29%), Positives = 81/182 (44%), Gaps = 37/182 (20%)
Query: 284 RCKCNGHAARCVRDR---DDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVA 340
RC CN +R RD ++S C C N GP+CD+C P+H W+ A+ + C
Sbjct: 430 RCDCNILGSR--RDMPCDEESGRCLCLPNVVGPKCDQCAPYH----WKLASGQGCEPCAC 483
Query: 341 CNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHC-----HYCKEGYYRDMGKPI 395
N + +C + G C CR G C C + Y D+
Sbjct: 484 DPHNSLSPQCN-----------QFTGQC-PCREGFGGLMCSAAAIRQCPDRTYGDVAT-- 529
Query: 396 THRKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIA----PC 451
C+ACDC G G C++ +G+C C+ G+TG C++C +GY +R P+ PC
Sbjct: 530 ----GCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGY-CNRYPVCVACHPC 584
Query: 452 IK 453
+
Sbjct: 585 FQ 586
>gi|190014607 netrin G2 [Homo sapiens]
Length = 530
Score = 204 bits (520), Expect = 1e-52
Identities = 125/398 (31%), Positives = 190/398 (47%), Gaps = 45/398 (11%)
Query: 69 TCGRPPARYCVVSERGEERLRSCHLCNASDPKKAHPPAFLTDLNNPHNLTCWQSENYLQF 128
TCG PP R+C E + C+AS+P AHPP + D T WQS + ++
Sbjct: 60 TCGDPPERFC----SHENPYLCSNECDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRY 115
Query: 129 PH--NVTLTLSLGKKFEVTY-VSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMY 185
P +TLS K E+T V + F RP M + KS+D GRTW P+QFY+ C + +
Sbjct: 116 PSPLEANITLSWNKTVELTDDVVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYAEDCMEAF 175
Query: 186 NRPHRAP--ITKQNEQEAVCTDSHTDMRPLSGGL-IAFSTLD-----GRPSAHDFDN--- 234
R ++ + +CT+ ++ + F D P + DN
Sbjct: 176 GMSARRARDMSSSSAHRVLCTEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYT 235
Query: 235 ----SPVLQDWVTATDIRVAFSRLHTFGDENEDDSELARDSYFYAVSDLQVGGRCKCNGH 290
+ L+++ T TD+R+ R G + ++ YFYA+S+++V GRCKCN H
Sbjct: 236 RLESAKGLKEFFTLTDLRMRLLRPALGGTYVQRENLY---KYFYAISNIEVIGRCKCNLH 292
Query: 291 AARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAR-----EANECVA----- 340
A C R+ SL C+C HNT GP+C +CK R W+ + N C
Sbjct: 293 ANLCSM-REGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFG 351
Query: 341 -CNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRK 399
C C H+ RC + L ++ C++C+HNT G+HC +C+ GYYR+ +
Sbjct: 352 NCECYGHSNRCSYIDFLNVVT-------CVSCKHNTRGQHCQHCRLGYYRNGSAELDDEN 404
Query: 400 ACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRC 437
C C+C+ +G+ CN+ TG C C++G G C+ C
Sbjct: 405 VCIECNCNQIGSVHDRCNE-TGFCECREGAAGPKCDDC 441
Score = 41.6 bits (96), Expect = 0.002
Identities = 35/159 (22%), Positives = 53/159 (33%), Gaps = 31/159 (19%)
Query: 341 CNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGK-----PI 395
C CNLHA C + G + C HNT G C CK+ + + P+
Sbjct: 287 CKCNLHANLCSM----------REGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPL 336
Query: 396 THRKACKACDCHPVGAAGKT-CNQTTGQCP------------CKDGVTGITCNRCAKGYQ 442
H C G+ G C + +C CK G C C GY
Sbjct: 337 PHGSPNA---CATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYY 393
Query: 443 QSRSPIAPCIKIPVAPPTTAASSVEEPEDCDSYCKASKG 481
++ S + + SV + + +C+ +G
Sbjct: 394 RNGSAELDDENVCIECNCNQIGSVHDRCNETGFCECREG 432
Score = 41.2 bits (95), Expect = 0.003
Identities = 18/41 (43%), Positives = 25/41 (60%), Gaps = 1/41 (2%)
Query: 286 KCNGHAARCVRDR-DDSLVCDCRHNTAGPECDRCKPFHYDR 325
+CN + V DR +++ C+CR AGP+CD C P HY R
Sbjct: 408 ECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWR 448
>gi|219842266 usherin isoform B [Homo sapiens]
Length = 5202
Score = 196 bits (497), Expect = 7e-50
Identities = 116/380 (30%), Positives = 186/380 (48%), Gaps = 30/380 (7%)
Query: 76 RYCVVSERGEERLRSCHLCNASDPKKAHPPAFLTDLNNPHNLTCWQSE---NYLQFPHNV 132
RYC+ ++ G+ N +AHP +F+ D + T W S N Q V
Sbjct: 317 RYCIPNDAGDTADNRVSRLNP----EAHPLSFVNDNDVG---TSWVSNVFTNITQLNQGV 369
Query: 133 TLTLSLGK-KFEVTYVSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMYNRPHRA 191
T+++ L +++V Y+ +QF SP+P + I + + W +Q+++ C + +
Sbjct: 370 TISVDLENGQYQVFYIIIQFFSPQPTEIRIQRKKENSLDWEDWQYFARNCGA-FGMKNNG 428
Query: 192 PITKQNEQEAVCTDSHTDMRPLSGGLIAFSTL----DGRPSAHDFDNSPVLQDWVTATDI 247
+ K + + + T P S G + FS L + RP ++F N+P LQ++V AT I
Sbjct: 429 DLEKPDSVNCLQLSNFT---PYSRGNVTFSILTPGPNYRPGYNNFYNTPSLQEFVKATQI 485
Query: 248 RVAFSRLHTFGDENEDDSELARDSYFYAVSDLQVGGRCKCNGHAARC-VRDRDDSLVCDC 306
R H G ++ + +YAV ++ + GRC+C+GHA C + +C
Sbjct: 486 R-----FHFHGQYYTTETAVNLRHRYYAVDEITISGRCQCHGHADNCDTTSQPYRCLCSQ 540
Query: 307 RHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSG---RK 363
T G CDRC P + D+P+++ A C C CN H++ C +N+ + R
Sbjct: 541 ESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFEHFRG 600
Query: 364 SGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKT--CNQTTG 421
GGVC +C HNT GR+C CK+ ++R +G + CK CDC VG + C+Q G
Sbjct: 601 GGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGG 660
Query: 422 QCPCKDGVTGITCNRCAKGY 441
QC CK V+G CN+C G+
Sbjct: 661 QCNCKRHVSGRQCNQCQNGF 680
Score = 84.7 bits (208), Expect = 2e-16
Identities = 56/174 (32%), Positives = 73/174 (41%), Gaps = 27/174 (15%)
Query: 273 FYAVSDLQVGGRCKCNGHAARCVRD----RDDSLVCDCRHNTAGPECDRCK-PFHYDRPW 327
FY + +L G CN + + V +S C C+ N G CD C F + R +
Sbjct: 680 FYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSF 739
Query: 328 QRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGY 387
C C CNLH +F G C C+ G C C+E +
Sbjct: 740 NDVG------CEPCQCNLHGSVNKFC--------NPHSGQC-ECKKEAKGLQCDTCRENF 784
Query: 388 YRDMGKPITHRKACKACDCHPVGAA-GKTCNQTTGQCPCKDGVTGITCNRCAKG 440
Y G +T+ CKACDC G+ G CN TGQC CK V G CN+C +G
Sbjct: 785 Y---GLDVTN---CKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEG 832
Score = 80.9 bits (198), Expect = 3e-15
Identities = 50/163 (30%), Positives = 69/163 (42%), Gaps = 37/163 (22%)
Query: 285 CKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCN 344
C+CN H + S C+C+ G +CD C+ Y + C AC+C+
Sbjct: 747 CQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFY--------GLDVTNCKACDCD 798
Query: 345 LHARRCRFNMELYKLSGRKSGGVC------LNCRHNTAGRHCHYCKEG--YYRDMGKPIT 396
+G G VC C+ N GR C+ C EG Y R +
Sbjct: 799 T--------------AGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFL- 843
Query: 397 HRKACKACDCHPVGAAGKT--CNQTTGQCPCKDGVTGITCNRC 437
C C+C G + CN++TGQCPCK GVTG+ CN+C
Sbjct: 844 ----CLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQC 882
Score = 73.6 bits (179), Expect = 5e-13
Identities = 49/192 (25%), Positives = 83/192 (43%), Gaps = 41/192 (21%)
Query: 266 ELARDSYFYAV----SDLQVGGRCKCNGHAARCVRDRDDSLVCD-------CRHNTAGPE 314
EL +D +F V S + V C C+ V R+ S++CD C+ + +G +
Sbjct: 618 ELCKDYFFRQVGADPSAIDVCKPCDCD-----TVGTRNGSILCDQIGGQCNCKRHVSGRQ 672
Query: 315 CDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHN 374
C++C+ Y+ + + C CNCN ++ ++ G C C+ N
Sbjct: 673 CNQCQNGFYN-----LQELDPDGCSPCNCNTSGTVDG------DITCHQNSGQC-KCKAN 720
Query: 375 TAGRHCHYCKEGY-----YRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQCPCKDGV 429
G C +C G+ + D+G C+ C C+ G+ K CN +GQC CK
Sbjct: 721 VIGLRCDHCNFGFKFLRSFNDVG--------CEPCQCNLHGSVNKFCNPHSGQCECKKEA 772
Query: 430 TGITCNRCAKGY 441
G+ C+ C + +
Sbjct: 773 KGLQCDTCRENF 784
Score = 73.2 bits (178), Expect = 7e-13
Identities = 49/157 (31%), Positives = 69/157 (43%), Gaps = 19/157 (12%)
Query: 304 CDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRK 363
C C N G C++C+P Y P A C+ C+C+ N L+G+
Sbjct: 920 CLCVPNRQGRRCNQCQPGFYISPGN------ATGCLPCSCHTTGA---VNHICNSLTGQ- 969
Query: 364 SGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQC 423
C+ + AG+ C CK+ Y+ P T R C+ C+CH GA +TC+ TGQC
Sbjct: 970 ----CVCQDASIAGQRCDQCKDHYFGF--DPQTGR--CQPCNCHLSGALNETCHLVTGQC 1021
Query: 424 PCKDGVTGITCNRCAKGYQQ-SRSPIAPCIKIPVAPP 459
CK VTG C+ C + + C K P P
Sbjct: 1022 FCKQFVTGSKCDACVPSASHLDVNNLLGCSKTPFQQP 1058
Score = 60.1 bits (144), Expect = 6e-09
Identities = 44/163 (26%), Positives = 68/163 (41%), Gaps = 22/163 (13%)
Query: 304 CDCRHNTAGPECDRCKPFHYDRPWQRATAREANE--CVACNCNLHARRCRFNMELYKLSG 361
C C+ N G +C++C ++ R+ N C+ CNC+ + L
Sbjct: 815 CICKPNVEGRQCNKCLEGNF-------YLRQNNSFLCLPCNCD------KTGTINGSLLC 861
Query: 362 RKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAA-GKTCNQTT 420
KS G C C+ G C+ C+ Y I + + C+ C+C +G G C+ +
Sbjct: 862 NKSTGQC-PCKLGVTGLRCNQCEPHRYN---LTIDNFQHCQMCECDSLGTLPGTICDPIS 917
Query: 421 GQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVAPPTTAA 463
GQC C G CN+C G+ S C +P + TT A
Sbjct: 918 GQCLCVPNRQGRRCNQCQPGFYISPGNATGC--LPCSCHTTGA 958
>gi|219842259 usherin isoform A [Homo sapiens]
Length = 1546
Score = 196 bits (497), Expect = 7e-50
Identities = 116/380 (30%), Positives = 186/380 (48%), Gaps = 30/380 (7%)
Query: 76 RYCVVSERGEERLRSCHLCNASDPKKAHPPAFLTDLNNPHNLTCWQSE---NYLQFPHNV 132
RYC+ ++ G+ N +AHP +F+ D + T W S N Q V
Sbjct: 317 RYCIPNDAGDTADNRVSRLNP----EAHPLSFVNDNDVG---TSWVSNVFTNITQLNQGV 369
Query: 133 TLTLSLGK-KFEVTYVSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMYNRPHRA 191
T+++ L +++V Y+ +QF SP+P + I + + W +Q+++ C + +
Sbjct: 370 TISVDLENGQYQVFYIIIQFFSPQPTEIRIQRKKENSLDWEDWQYFARNCGA-FGMKNNG 428
Query: 192 PITKQNEQEAVCTDSHTDMRPLSGGLIAFSTL----DGRPSAHDFDNSPVLQDWVTATDI 247
+ K + + + T P S G + FS L + RP ++F N+P LQ++V AT I
Sbjct: 429 DLEKPDSVNCLQLSNFT---PYSRGNVTFSILTPGPNYRPGYNNFYNTPSLQEFVKATQI 485
Query: 248 RVAFSRLHTFGDENEDDSELARDSYFYAVSDLQVGGRCKCNGHAARC-VRDRDDSLVCDC 306
R H G ++ + +YAV ++ + GRC+C+GHA C + +C
Sbjct: 486 R-----FHFHGQYYTTETAVNLRHRYYAVDEITISGRCQCHGHADNCDTTSQPYRCLCSQ 540
Query: 307 RHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSG---RK 363
T G CDRC P + D+P+++ A C C CN H++ C +N+ + R
Sbjct: 541 ESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFEHFRG 600
Query: 364 SGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKT--CNQTTG 421
GGVC +C HNT GR+C CK+ ++R +G + CK CDC VG + C+Q G
Sbjct: 601 GGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGG 660
Query: 422 QCPCKDGVTGITCNRCAKGY 441
QC CK V+G CN+C G+
Sbjct: 661 QCNCKRHVSGRQCNQCQNGF 680
Score = 84.7 bits (208), Expect = 2e-16
Identities = 56/174 (32%), Positives = 73/174 (41%), Gaps = 27/174 (15%)
Query: 273 FYAVSDLQVGGRCKCNGHAARCVRD----RDDSLVCDCRHNTAGPECDRCK-PFHYDRPW 327
FY + +L G CN + + V +S C C+ N G CD C F + R +
Sbjct: 680 FYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSF 739
Query: 328 QRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGY 387
C C CNLH +F G C C+ G C C+E +
Sbjct: 740 NDVG------CEPCQCNLHGSVNKFC--------NPHSGQC-ECKKEAKGLQCDTCRENF 784
Query: 388 YRDMGKPITHRKACKACDCHPVGAA-GKTCNQTTGQCPCKDGVTGITCNRCAKG 440
Y G +T+ CKACDC G+ G CN TGQC CK V G CN+C +G
Sbjct: 785 Y---GLDVTN---CKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEG 832
Score = 80.9 bits (198), Expect = 3e-15
Identities = 50/163 (30%), Positives = 69/163 (42%), Gaps = 37/163 (22%)
Query: 285 CKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCN 344
C+CN H + S C+C+ G +CD C+ Y + C AC+C+
Sbjct: 747 CQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFY--------GLDVTNCKACDCD 798
Query: 345 LHARRCRFNMELYKLSGRKSGGVC------LNCRHNTAGRHCHYCKEG--YYRDMGKPIT 396
+G G VC C+ N GR C+ C EG Y R +
Sbjct: 799 T--------------AGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFL- 843
Query: 397 HRKACKACDCHPVGAAGKT--CNQTTGQCPCKDGVTGITCNRC 437
C C+C G + CN++TGQCPCK GVTG+ CN+C
Sbjct: 844 ----CLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQC 882
Score = 73.6 bits (179), Expect = 5e-13
Identities = 49/192 (25%), Positives = 83/192 (43%), Gaps = 41/192 (21%)
Query: 266 ELARDSYFYAV----SDLQVGGRCKCNGHAARCVRDRDDSLVCD-------CRHNTAGPE 314
EL +D +F V S + V C C+ V R+ S++CD C+ + +G +
Sbjct: 618 ELCKDYFFRQVGADPSAIDVCKPCDCD-----TVGTRNGSILCDQIGGQCNCKRHVSGRQ 672
Query: 315 CDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHN 374
C++C+ Y+ + + C CNCN ++ ++ G C C+ N
Sbjct: 673 CNQCQNGFYN-----LQELDPDGCSPCNCNTSGTVDG------DITCHQNSGQC-KCKAN 720
Query: 375 TAGRHCHYCKEGY-----YRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQCPCKDGV 429
G C +C G+ + D+G C+ C C+ G+ K CN +GQC CK
Sbjct: 721 VIGLRCDHCNFGFKFLRSFNDVG--------CEPCQCNLHGSVNKFCNPHSGQCECKKEA 772
Query: 430 TGITCNRCAKGY 441
G+ C+ C + +
Sbjct: 773 KGLQCDTCRENF 784
Score = 73.2 bits (178), Expect = 7e-13
Identities = 49/157 (31%), Positives = 69/157 (43%), Gaps = 19/157 (12%)
Query: 304 CDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRK 363
C C N G C++C+P Y P A C+ C+C+ N L+G+
Sbjct: 920 CLCVPNRQGRRCNQCQPGFYISPGN------ATGCLPCSCHTTGA---VNHICNSLTGQ- 969
Query: 364 SGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQC 423
C+ + AG+ C CK+ Y+ P T R C+ C+CH GA +TC+ TGQC
Sbjct: 970 ----CVCQDASIAGQRCDQCKDHYFGF--DPQTGR--CQPCNCHLSGALNETCHLVTGQC 1021
Query: 424 PCKDGVTGITCNRCAKGYQQ-SRSPIAPCIKIPVAPP 459
CK VTG C+ C + + C K P P
Sbjct: 1022 FCKQFVTGSKCDACVPSASHLDVNNLLGCSKTPFQQP 1058
Score = 60.1 bits (144), Expect = 6e-09
Identities = 44/163 (26%), Positives = 68/163 (41%), Gaps = 22/163 (13%)
Query: 304 CDCRHNTAGPECDRCKPFHYDRPWQRATAREANE--CVACNCNLHARRCRFNMELYKLSG 361
C C+ N G +C++C ++ R+ N C+ CNC+ + L
Sbjct: 815 CICKPNVEGRQCNKCLEGNF-------YLRQNNSFLCLPCNCD------KTGTINGSLLC 861
Query: 362 RKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAA-GKTCNQTT 420
KS G C C+ G C+ C+ Y I + + C+ C+C +G G C+ +
Sbjct: 862 NKSTGQC-PCKLGVTGLRCNQCEPHRYN---LTIDNFQHCQMCECDSLGTLPGTICDPIS 917
Query: 421 GQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVAPPTTAA 463
GQC C G CN+C G+ S C +P + TT A
Sbjct: 918 GQCLCVPNRQGRRCNQCQPGFYISPGNATGC--LPCSCHTTGA 958
>gi|54312078 netrin G1 isoform 3 [Homo sapiens]
Length = 438
Score = 175 bits (444), Expect = 9e-44
Identities = 114/367 (31%), Positives = 170/367 (46%), Gaps = 41/367 (11%)
Query: 69 TCGRPPARYCVVSERGEERLRSCHLCNASDPKKAHPPAFLTDLNNPHNLTCWQSENYLQF 128
TCG PP +C + + C+AS P+ AHPP + D H T WQS + ++
Sbjct: 71 TCGDPPETFCAMGNP----YMCNNECDASTPELAHPPELMFDFEGRHPSTFWQSATWKEY 126
Query: 129 PH--NVTLTLSLGKKFEVT-YVSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMY 185
P V +TLS K E+T + + F S RP+ M + KS+DYGRTW P+Q+Y+T C +
Sbjct: 127 PKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAF 186
Query: 186 NRPHRA--PITKQNEQEAVCTDSHTDMRPLSGGLIAFSTLD-----GRPSAHD------- 231
+ ++ +++ E +CT+ ++ + +I F D P +
Sbjct: 187 HMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQ 246
Query: 232 FDNSPVLQDWVTATDIRVAFSRLHTFGDENEDDSELARDSYFYAVSDLQVGGRCKCNGHA 291
D + L+D+ T TD+R+ R G+ D+ LAR YFYA+SD++V GRCKCN HA
Sbjct: 247 LDTTKKLRDFFTVTDLRIRLLR-PAVGEIFVDELHLAR--YFYAISDIKVRGRCKCNLHA 303
Query: 292 ARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCR 351
CV D + L C+C HNT GP+C +CK + RPW + + A C
Sbjct: 304 TVCVYD-NSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIG 362
Query: 352 FNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGA 411
N+ +L ++GG C HN C G C+ C G+
Sbjct: 363 TNVCDNELLHCQNGGTC----HNNVRCLCPAAYTGI------------LCEKLRCEEAGS 406
Query: 412 AGKTCNQ 418
G Q
Sbjct: 407 CGSDSGQ 413
Score = 31.2 bits (69), Expect = 2.9
Identities = 29/117 (24%), Positives = 44/117 (37%), Gaps = 11/117 (9%)
Query: 398 RKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVA 457
R CK C+ H T C C+ TG C +C K YQ + IP
Sbjct: 294 RGRCK-CNLHATVCVYDNSKLT---CECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKG 349
Query: 458 PPTTAASSVEE--PEDCDS---YCKASKGKLKINMKKYCKKDY-AVQIHILKADKAG 508
T S+ CD+ +C+ + G N++ C Y + L+ ++AG
Sbjct: 350 TANTCIPSISSIGTNVCDNELLHCQ-NGGTCHNNVRCLCPAAYTGILCEKLRCEEAG 405
>gi|164414437 netrin G1 isoform 2 [Homo sapiens]
Length = 480
Score = 173 bits (438), Expect = 5e-43
Identities = 98/276 (35%), Positives = 146/276 (52%), Gaps = 25/276 (9%)
Query: 69 TCGRPPARYCVVSERGEERLRSCHLCNASDPKKAHPPAFLTDLNNPHNLTCWQSENYLQF 128
TCG PP +C + + C+AS P+ AHPP + D H T WQS + ++
Sbjct: 71 TCGDPPETFCAMGNP----YMCNNECDASTPELAHPPELMFDFEGRHPSTFWQSATWKEY 126
Query: 129 PH--NVTLTLSLGKKFEVT-YVSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMY 185
P V +TLS K E+T + + F S RP+ M + KS+DYGRTW P+Q+Y+T C +
Sbjct: 127 PKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAF 186
Query: 186 NRPHRA--PITKQNEQEAVCTDSHTDMRPLSGGLIAFSTLD-----GRPSAHD------- 231
+ ++ +++ E +CT+ ++ + +I F D P +
Sbjct: 187 HMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQ 246
Query: 232 FDNSPVLQDWVTATDIRVAFSRLHTFGDENEDDSELARDSYFYAVSDLQVGGRCKCNGHA 291
D + L+D+ T TD+R+ R G+ D+ LAR YFYA+SD++V GRCKCN HA
Sbjct: 247 LDTTKKLRDFFTVTDLRIRLLR-PAVGEIFVDELHLAR--YFYAISDIKVRGRCKCNLHA 303
Query: 292 ARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPW 327
CV D + L C+C HNT GP+C +CK + RPW
Sbjct: 304 TVCVYD-NSKLTCECEHNTTGPDCGKCKKNYQGRPW 338
>gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens]
Length = 1111
Score = 94.0 bits (232), Expect = 4e-19
Identities = 49/124 (39%), Positives = 67/124 (54%), Gaps = 12/124 (9%)
Query: 318 CKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAG 377
C F P RAT+R C+CN +R+C F+ EL++ +G +G CLNC NT G
Sbjct: 9 CLCFSLLLPAARATSRRE----VCDCNGKSRQCIFDRELHRQTG--NGFRCLNCNDNTDG 62
Query: 378 RHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRC 437
HC CK G+YR R C C+C+ G+ C+ +G+C CK GVTG C+RC
Sbjct: 63 IHCEKCKNGFYRH-----RERDRCLPCNCNSKGSLSARCD-NSGRCSCKPGVTGARCDRC 116
Query: 438 AKGY 441
G+
Sbjct: 117 LPGF 120
Score = 87.0 bits (214), Expect = 4e-17
Identities = 54/166 (32%), Positives = 71/166 (42%), Gaps = 29/166 (17%)
Query: 285 CKCNGHAARCVRDRD------DSLVC-DCRHNTAGPECDRCKPFHYDRPWQRATAREANE 337
C CNG + +C+ DR+ + C +C NT G C++CK Y RE +
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRH-------RERDR 80
Query: 338 CVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYR--DMGKPI 395
C+ CNCN LS R +C+ G C C G++ D G
Sbjct: 81 CLPCNCNSKG----------SLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQ 130
Query: 396 THRKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKGY 441
R CDC P G AG C+ G+C CK VTG C+RC GY
Sbjct: 131 DQRLLDSKCDCDPAGIAGP-CD--AGRCVCKPAVTGERCDRCRSGY 173
Score = 78.2 bits (191), Expect = 2e-14
Identities = 54/183 (29%), Positives = 79/183 (43%), Gaps = 12/183 (6%)
Query: 258 GDENED-DSELARDSYFYAVSDLQVGGRCKCNGHAARCVRDRDDSLVCD-CRHNTAGPEC 315
GDEN D + ++ D + C C+ + V + +VC+ C G C
Sbjct: 434 GDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARC 493
Query: 316 DRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNT 375
+ C ++ P+ C C CN + +L+GR CL C HNT
Sbjct: 494 ELCADGYFGDPF--GEHGPVRPCQPCQCNNNVDPSASG-NCDRLTGR-----CLKCIHNT 545
Query: 376 AGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCN 435
AG +C CK GY+ D P K C+AC+C+P+G+ C ++ G C CK G G C
Sbjct: 546 AGIYCDQCKAGYFGDPLAPNPADK-CRACNCNPMGSEPVGC-RSDGTCVCKPGFGGPNCE 603
Query: 436 RCA 438
A
Sbjct: 604 HGA 606
Score = 58.2 bits (139), Expect = 2e-08
Identities = 46/169 (27%), Positives = 64/169 (37%), Gaps = 23/169 (13%)
Query: 285 CKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCN 344
C C G A C D D C EC C Y+ P + C C C+
Sbjct: 416 CNCQGGGA-CDPDTGD---CYSGDENPDIECADCPIGFYNDP------HDPRSCKPCPCH 465
Query: 345 LHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKAC 404
+ C E ++ VC NC G C C +GY+ D + C+ C
Sbjct: 466 -NGFSCSVMPETEEV-------VCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPC 517
Query: 405 DCHPV--GAAGKTCNQTTGQC-PCKDGVTGITCNRCAKGYQQSRSPIAP 450
C+ +A C++ TG+C C GI C++C GY P+AP
Sbjct: 518 QCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGY--FGDPLAP 564
Score = 45.8 bits (107), Expect = 1e-04
Identities = 40/153 (26%), Positives = 51/153 (33%), Gaps = 33/153 (21%)
Query: 325 RPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSG--GVCLNCRHNTAGR---- 378
RP A A +C+ C + C+ YK + G G C+ C G
Sbjct: 369 RPVSGAPAPWVEQCI-CPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPD 427
Query: 379 -------------HCHYCKEGYYRDMGKPITHRKACKACDCH---PVGAAGKTCNQTTGQ 422
C C G+Y D P ++CK C CH +T
Sbjct: 428 TGDCYSGDENPDIECADCPIGFYNDPHDP----RSCKPCPCHNGFSCSVMPETEEVVCNN 483
Query: 423 CPCKDGVTGITCNRCAKGY----QQSRSPIAPC 451
CP GVTG C CA GY P+ PC
Sbjct: 484 CP--PGVTGARCELCADGYFGDPFGEHGPVRPC 514
Score = 36.6 bits (83), Expect = 0.068
Identities = 24/85 (28%), Positives = 30/85 (35%), Gaps = 5/85 (5%)
Query: 371 CRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQCPCKDGVT 430
C G+ C C GY RD + + C C+C GA C+ TG C D
Sbjct: 384 CPVGYKGQFCQDCASGYKRDSAR-LGPFGTCIPCNCQGGGA----CDPDTGDCYSGDENP 438
Query: 431 GITCNRCAKGYQQSRSPIAPCIKIP 455
I C C G+ C P
Sbjct: 439 DIECADCPIGFYNDPHDPRSCKPCP 463
Score = 34.7 bits (78), Expect = 0.26
Identities = 21/74 (28%), Positives = 29/74 (39%), Gaps = 12/74 (16%)
Query: 284 RCKCN--GHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVAC 341
+C C+ G A C R C C+ G CDRC+ +Y+ C C
Sbjct: 138 KCDCDPAGIAGPCDAGR-----CVCKPAVTGERCDRCRSGYYN-----LDGGNPEGCTQC 187
Query: 342 NCNLHARRCRFNME 355
C H+ CR + E
Sbjct: 188 FCYGHSASCRSSAE 201
>gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens]
Length = 1193
Score = 94.0 bits (232), Expect = 4e-19
Identities = 49/124 (39%), Positives = 67/124 (54%), Gaps = 12/124 (9%)
Query: 318 CKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAG 377
C F P RAT+R C+CN +R+C F+ EL++ +G +G CLNC NT G
Sbjct: 9 CLCFSLLLPAARATSRRE----VCDCNGKSRQCIFDRELHRQTG--NGFRCLNCNDNTDG 62
Query: 378 RHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRC 437
HC CK G+YR R C C+C+ G+ C+ +G+C CK GVTG C+RC
Sbjct: 63 IHCEKCKNGFYRH-----RERDRCLPCNCNSKGSLSARCD-NSGRCSCKPGVTGARCDRC 116
Query: 438 AKGY 441
G+
Sbjct: 117 LPGF 120
Score = 87.0 bits (214), Expect = 4e-17
Identities = 54/166 (32%), Positives = 71/166 (42%), Gaps = 29/166 (17%)
Query: 285 CKCNGHAARCVRDRD------DSLVC-DCRHNTAGPECDRCKPFHYDRPWQRATAREANE 337
C CNG + +C+ DR+ + C +C NT G C++CK Y RE +
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRH-------RERDR 80
Query: 338 CVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYR--DMGKPI 395
C+ CNCN LS R +C+ G C C G++ D G
Sbjct: 81 CLPCNCNSKG----------SLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQ 130
Query: 396 THRKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKGY 441
R CDC P G AG C+ G+C CK VTG C+RC GY
Sbjct: 131 DQRLLDSKCDCDPAGIAGP-CD--AGRCVCKPAVTGERCDRCRSGY 173
Score = 78.2 bits (191), Expect = 2e-14
Identities = 54/183 (29%), Positives = 79/183 (43%), Gaps = 12/183 (6%)
Query: 258 GDENED-DSELARDSYFYAVSDLQVGGRCKCNGHAARCVRDRDDSLVCD-CRHNTAGPEC 315
GDEN D + ++ D + C C+ + V + +VC+ C G C
Sbjct: 434 GDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARC 493
Query: 316 DRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNT 375
+ C ++ P+ C C CN + +L+GR CL C HNT
Sbjct: 494 ELCADGYFGDPF--GEHGPVRPCQPCQCNNNVDPSASG-NCDRLTGR-----CLKCIHNT 545
Query: 376 AGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCN 435
AG +C CK GY+ D P K C+AC+C+P+G+ C ++ G C CK G G C
Sbjct: 546 AGIYCDQCKAGYFGDPLAPNPADK-CRACNCNPMGSEPVGC-RSDGTCVCKPGFGGPNCE 603
Query: 436 RCA 438
A
Sbjct: 604 HGA 606
Score = 58.2 bits (139), Expect = 2e-08
Identities = 46/169 (27%), Positives = 64/169 (37%), Gaps = 23/169 (13%)
Query: 285 CKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCN 344
C C G A C D D C EC C Y+ P + C C C+
Sbjct: 416 CNCQGGGA-CDPDTGD---CYSGDENPDIECADCPIGFYNDP------HDPRSCKPCPCH 465
Query: 345 LHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKAC 404
+ C E ++ VC NC G C C +GY+ D + C+ C
Sbjct: 466 -NGFSCSVMPETEEV-------VCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPC 517
Query: 405 DCHPV--GAAGKTCNQTTGQC-PCKDGVTGITCNRCAKGYQQSRSPIAP 450
C+ +A C++ TG+C C GI C++C GY P+AP
Sbjct: 518 QCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGY--FGDPLAP 564
Score = 45.8 bits (107), Expect = 1e-04
Identities = 40/153 (26%), Positives = 51/153 (33%), Gaps = 33/153 (21%)
Query: 325 RPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSG--GVCLNCRHNTAGR---- 378
RP A A +C+ C + C+ YK + G G C+ C G
Sbjct: 369 RPVSGAPAPWVEQCI-CPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPD 427
Query: 379 -------------HCHYCKEGYYRDMGKPITHRKACKACDCH---PVGAAGKTCNQTTGQ 422
C C G+Y D P ++CK C CH +T
Sbjct: 428 TGDCYSGDENPDIECADCPIGFYNDPHDP----RSCKPCPCHNGFSCSVMPETEEVVCNN 483
Query: 423 CPCKDGVTGITCNRCAKGY----QQSRSPIAPC 451
CP GVTG C CA GY P+ PC
Sbjct: 484 CP--PGVTGARCELCADGYFGDPFGEHGPVRPC 514
Score = 36.6 bits (83), Expect = 0.068
Identities = 24/85 (28%), Positives = 30/85 (35%), Gaps = 5/85 (5%)
Query: 371 CRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQCPCKDGVT 430
C G+ C C GY RD + + C C+C GA C+ TG C D
Sbjct: 384 CPVGYKGQFCQDCASGYKRDSAR-LGPFGTCIPCNCQGGGA----CDPDTGDCYSGDENP 438
Query: 431 GITCNRCAKGYQQSRSPIAPCIKIP 455
I C C G+ C P
Sbjct: 439 DIECADCPIGFYNDPHDPRSCKPCP 463
Score = 34.7 bits (78), Expect = 0.26
Identities = 21/74 (28%), Positives = 29/74 (39%), Gaps = 12/74 (16%)
Query: 284 RCKCN--GHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVAC 341
+C C+ G A C R C C+ G CDRC+ +Y+ C C
Sbjct: 138 KCDCDPAGIAGPCDAGR-----CVCKPAVTGERCDRCRSGYYN-----LDGGNPEGCTQC 187
Query: 342 NCNLHARRCRFNME 355
C H+ CR + E
Sbjct: 188 FCYGHSASCRSSAE 201
>gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens]
Length = 1668
Score = 94.0 bits (232), Expect = 4e-19
Identities = 61/177 (34%), Positives = 78/177 (44%), Gaps = 40/177 (22%)
Query: 318 CKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAG 377
C P +Y T R CV CNCN H+ +C+ G+C+NC+HNTAG
Sbjct: 59 CSPGYYRDHKGLYTGR----CVPCNCNGHSNQCQ-----------DGSGICVNCQHNTAG 103
Query: 378 RHCHYCKEGYYRDMGKPITHRKACKACDCHPVG--AAGKTCNQTTGQCPCKDGVTGITCN 435
HC C+EGYY G + +C+AC C A G N +C CK G TG C
Sbjct: 104 EHCERCQEGYY---GNAV--HGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCE 158
Query: 436 RCAKGY----QQSRSPIAPCI-----KIPVAPPTTA---------ASSVEEPEDCDS 474
RCA GY Q+ PC ++ P T +S EE +DCDS
Sbjct: 159 RCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDS 215
Score = 75.9 bits (185), Expect = 1e-13
Identities = 50/160 (31%), Positives = 68/160 (42%), Gaps = 31/160 (19%)
Query: 285 CKCNGHAARCVRDRDDSLVC-DCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNC 343
C CNGH+ +C +D S +C +C+HNTAG C+RC+ +Y C AC C
Sbjct: 78 CNCNGHSNQC---QDGSGICVNCQHNTAGEHCERCQEGYYGNAVH-------GSCRACPC 127
Query: 344 ---NLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKA 400
N A C N G V +C+ G C C GY+ G P +
Sbjct: 128 PHTNSFATGCVVN----------GGDVRCSCKAGYTGTQCERCAPGYF---GNPQKFGGS 174
Query: 401 CKACDCHPVGAAGKTCNQTTGQC---PCKDGVTGITCNRC 437
C+ C C+ G G +C+ TG C KD C+ C
Sbjct: 175 CQPCSCNSNGQLG-SCHPLTGDCINQEPKDSSPAEECDDC 213
>gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens]
Length = 1724
Score = 94.0 bits (232), Expect = 4e-19
Identities = 61/177 (34%), Positives = 78/177 (44%), Gaps = 40/177 (22%)
Query: 318 CKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAG 377
C P +Y T R CV CNCN H+ +C+ G+C+NC+HNTAG
Sbjct: 59 CSPGYYRDHKGLYTGR----CVPCNCNGHSNQCQ-----------DGSGICVNCQHNTAG 103
Query: 378 RHCHYCKEGYYRDMGKPITHRKACKACDCHPVG--AAGKTCNQTTGQCPCKDGVTGITCN 435
HC C+EGYY G + +C+AC C A G N +C CK G TG C
Sbjct: 104 EHCERCQEGYY---GNAV--HGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCE 158
Query: 436 RCAKGY----QQSRSPIAPCI-----KIPVAPPTTA---------ASSVEEPEDCDS 474
RCA GY Q+ PC ++ P T +S EE +DCDS
Sbjct: 159 RCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDS 215
Score = 75.9 bits (185), Expect = 1e-13
Identities = 50/160 (31%), Positives = 68/160 (42%), Gaps = 31/160 (19%)
Query: 285 CKCNGHAARCVRDRDDSLVC-DCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNC 343
C CNGH+ +C +D S +C +C+HNTAG C+RC+ +Y C AC C
Sbjct: 78 CNCNGHSNQC---QDGSGICVNCQHNTAGEHCERCQEGYYGNAVH-------GSCRACPC 127
Query: 344 ---NLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKA 400
N A C N G V +C+ G C C GY+ G P +
Sbjct: 128 PHTNSFATGCVVN----------GGDVRCSCKAGYTGTQCERCAPGYF---GNPQKFGGS 174
Query: 401 CKACDCHPVGAAGKTCNQTTGQC---PCKDGVTGITCNRC 437
C+ C C+ G G +C+ TG C KD C+ C
Sbjct: 175 CQPCSCNSNGQLG-SCHPLTGDCINQEPKDSSPAEECDDC 213
>gi|122937440 multiple EGF-like-domains 9 [Homo sapiens]
Length = 639
Score = 87.4 bits (215), Expect = 3e-17
Identities = 52/171 (30%), Positives = 69/171 (40%), Gaps = 28/171 (16%)
Query: 285 CKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCN 344
C C+ H A + + S C C+ G CDRC+ +Y N C+ C CN
Sbjct: 291 CDCSPHGALSI-PCNSSGKCQCKVGVIGSICDRCQDGYY--------GFSKNGCLPCQCN 341
Query: 345 LHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKAC 404
+ C G CLNC+ N+ G HC CKEG+Y+ K C C
Sbjct: 342 NRSASCD-----------ALTGACLNCQENSKGNHCEECKEGFYQSPDA----TKECLRC 386
Query: 405 DCHPVGAAGKTCNQTTGQCP----CKDGVTGITCNRCAKGYQQSRSPIAPC 451
C V + G +++ P CKDG G CN+C GY S C
Sbjct: 387 PCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGYYNFDSICRKC 437
Score = 75.9 bits (185), Expect = 1e-13
Identities = 51/187 (27%), Positives = 73/187 (39%), Gaps = 28/187 (14%)
Query: 285 CKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCN 344
C+CN +A C D +C+ N+ G C+ CK Y P EC+ C C+
Sbjct: 338 CQCNNRSASC--DALTGACLNCQENSKGNHCEECKEGFYQSP------DATKECLRCPCS 389
Query: 345 LHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKAC 404
+++ +L C C+ G +C+ C+ GYY C+ C
Sbjct: 390 AVTSTGSCSIKSSELEPE-----CDQCKDGYIGPNCNKCENGYYN-------FDSICRKC 437
Query: 405 DCH----PVGAAGKTCNQTTGQC-PCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVAPP 459
CH PV K C +G+C C TG C C +GY CIK V P
Sbjct: 438 QCHGHVDPVKTP-KICKPESGECINCLHNTTGFWCENCLEGYVHDLE--GNCIKKEVILP 494
Query: 460 TTAASSV 466
T S++
Sbjct: 495 TPEGSTI 501
Score = 63.2 bits (152), Expect = 7e-10
Identities = 48/194 (24%), Positives = 73/194 (37%), Gaps = 29/194 (14%)
Query: 304 CDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRK 363
C+CR G C+ CK Y + C C+C+ H
Sbjct: 261 CECRPGYQGLHCETCKEGFY-------LNYTSGLCQPCDCSPHGALS---------IPCN 304
Query: 364 SGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQC 423
S G C C+ G C C++GYY + C C C+ A+ C+ TG C
Sbjct: 305 SSGKC-QCKVGVIGSICDRCQDGYYG------FSKNGCLPCQCNNRSAS---CDALTGAC 354
Query: 424 -PCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVAPPTTAASSVEEPEDCDSYCKASK-G 481
C++ G C C +G+ QS C++ P + T+ S + + + C K G
Sbjct: 355 LNCQENSKGNHCEECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKSSELEPECDQCKDG 414
Query: 482 KLKINMKKYCKKDY 495
+ N K C+ Y
Sbjct: 415 YIGPNCNK-CENGY 427
Score = 47.4 bits (111), Expect = 4e-05
Identities = 22/69 (31%), Positives = 35/69 (50%), Gaps = 7/69 (10%)
Query: 380 CHYCKEGYYRDMGKPITHRKACKA------CDCHPVGAAG-KTCNQTTGQCPCKDGVTGI 432
C + Y + +P+ + + +A C+C VG+ CNQTTGQC C+ G G+
Sbjct: 211 CESNLKSKYLPLTQPVMNLRVSEAVKTEYVCNCSVVGSLNVNRCNQTTGQCECRPGYQGL 270
Query: 433 TCNRCAKGY 441
C C +G+
Sbjct: 271 HCETCKEGF 279
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 84.3 bits (207), Expect = 3e-16
Identities = 50/165 (30%), Positives = 73/165 (44%), Gaps = 26/165 (15%)
Query: 284 RCKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNC 343
RC C+GH+ C + + C+H+T GP C++C+P +Y QR T + +C C C
Sbjct: 1158 RCSCHGHSEAC--EPETGACQGCQHHTEGPRCEQCQPGYYGDA-QRGTPQ---DCQLCPC 1211
Query: 344 ------NLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRD--MGKPI 395
A C + + + C C +GRHC C GYY + G+P
Sbjct: 1212 YGDPAAGQAAHTCFLDTDGHP--------TCDACSPGHSGRHCERCAPGYYGNPSQGQPC 1263
Query: 396 THRKACK---ACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRC 437
C+C P G+ C+ GQC CK V G+TC+ C
Sbjct: 1264 QRDSQVPGPIGCNCDPQGSVSSQCD-AAGQCQCKAQVEGLTCSHC 1307
Score = 75.5 bits (184), Expect = 1e-13
Identities = 53/172 (30%), Positives = 75/172 (43%), Gaps = 15/172 (8%)
Query: 285 CKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCN 344
C CNGHA+ C D +C+HNT GP+C++CK + A A C C C
Sbjct: 764 CNCNGHASSC--DPVYGHCLNCQHNTEGPQCNKCKAGFFGD----AMKATATSCRPCPCP 817
Query: 345 LHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKAC 404
RF+ + + ++ C C GR C C GY G PI C+
Sbjct: 818 YIDASRRFSDTCFLDTDGQA--TCDACAPGYTGRRCESCAPGYE---GNPIQPGGKCRPV 872
Query: 405 DCHPVGAAGKTCNQTTGQ-CPCKDGVTGITCNRCAKG--YQQSRSPIAPCIK 453
+ V + T+G+ C CK+ V G CN CA G + +R+P C+K
Sbjct: 873 NQEIVRCDERGSMGTSGEACRCKNNVVGRLCNECADGSFHLSTRNPDG-CLK 923
Score = 73.9 bits (180), Expect = 4e-13
Identities = 52/154 (33%), Positives = 67/154 (43%), Gaps = 26/154 (16%)
Query: 304 CDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRK 363
C C +G C+ C H+ R C CNCN HA C +Y
Sbjct: 731 CRCPIGYSGLSCESCDA-HFTRV---PGGPYLGTCSGCNCNGHASSCD---PVY------ 777
Query: 364 SGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGK---TC-NQT 419
G CLNC+HNT G C+ CK G++ D K +C+ C C + A+ + TC T
Sbjct: 778 --GHCLNCQHNTEGPQCNKCKAGFFGDAMKATA--TSCRPCPCPYIDASRRFSDTCFLDT 833
Query: 420 TGQC---PCKDGVTGITCNRCAKGYQQSRSPIAP 450
GQ C G TG C CA GY+ +PI P
Sbjct: 834 DGQATCDACAPGYTGRRCESCAPGYE--GNPIQP 865
Score = 73.6 bits (179), Expect = 5e-13
Identities = 48/157 (30%), Positives = 62/157 (39%), Gaps = 28/157 (17%)
Query: 304 CDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRK 363
C C GP C C + P + C C+C+ H+ C
Sbjct: 1126 CSCPPGYRGPSCQDCDTGYTRTP----SGLYLGTCERCSCHGHSEACE-----------P 1170
Query: 364 SGGVCLNCRHNTAGRHCHYCKEGYYRD--MGKPITHRKACKACDCHPVGAAGK---TCNQ 418
G C C+H+T G C C+ GYY D G P + C+ C C+ AAG+ TC
Sbjct: 1171 ETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTP----QDCQLCPCYGDPAAGQAAHTCFL 1226
Query: 419 TTGQCP----CKDGVTGITCNRCAKGYQQSRSPIAPC 451
T P C G +G C RCA GY + S PC
Sbjct: 1227 DTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQGQPC 1263
Score = 64.3 bits (155), Expect = 3e-10
Identities = 40/149 (26%), Positives = 52/149 (34%), Gaps = 32/149 (21%)
Query: 304 CDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRK 363
C C G C C P + + + C C CN H+ C
Sbjct: 1530 CRCPPGYIGLSCQDCAPGYT----RTGSGLYLGHCELCECNGHSDLCH-----------P 1574
Query: 364 SGGVCLNCRHNTAGRHCHYCKEGYYRD-----------MGKPITHRKACKACDCHPVGAA 412
G C C+HN AG C C GYY D P+T+ + + C +GA
Sbjct: 1575 ETGACSQCQHNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAG 1634
Query: 413 GKTCNQTTGQCPCKDGVTGITCNRCAKGY 441
G C C+ G TG C +C GY
Sbjct: 1635 GYRCT------ACEPGYTGQYCEQCGPGY 1657
Score = 57.0 bits (136), Expect = 5e-08
Identities = 35/117 (29%), Positives = 46/117 (39%), Gaps = 11/117 (9%)
Query: 285 CKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCN 344
C+CNGH+ C + C+HN AG C+ C P +Y ATA +C C C
Sbjct: 1563 CECNGHSDLC--HPETGACSQCQHNAAGEFCELCAPGYYG----DATAGTPEDCQPCACP 1616
Query: 345 LHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKAC 401
L F+ L G C C G++C C GY +G P C
Sbjct: 1617 LTNPENMFSRTCESLGA--GGYRCTACEPGYTGQYCEQCGPGY---VGNPSVQGGQC 1668
Score = 38.1 bits (87), Expect = 0.023
Identities = 28/93 (30%), Positives = 35/93 (37%), Gaps = 8/93 (8%)
Query: 371 CRHNTAGRHCHYCKEGYYRD-MGKPITHRKACKACDCHPVGAAGKTCNQTTGQCP-CKDG 428
C G C C GY R G + H C+ C+C+ C+ TG C C+
Sbjct: 1532 CPPGYIGLSCQDCAPGYTRTGSGLYLGH---CELCECN---GHSDLCHPETGACSQCQHN 1585
Query: 429 VTGITCNRCAKGYQQSRSPIAPCIKIPVAPPTT 461
G C CA GY + P P A P T
Sbjct: 1586 AAGEFCELCAPGYYGDATAGTPEDCQPCACPLT 1618
Score = 34.7 bits (78), Expect = 0.26
Identities = 20/74 (27%), Positives = 30/74 (40%), Gaps = 6/74 (8%)
Query: 278 DLQVGGRCKCNGHAARCVRDRDDSL-VCDCRHNTAGPECDRCKPFHYDRPWQRATAREAN 336
D QV G CN V + D+ C C+ G C C+P H+ +A +
Sbjct: 1266 DSQVPGPIGCNCDPQGSVSSQCDAAGQCQCKAQVEGLTCSHCRPHHF-----HLSASNPD 1320
Query: 337 ECVACNCNLHARRC 350
C+ C C ++C
Sbjct: 1321 GCLPCFCMGITQQC 1334
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.135 0.445
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,550,666
Number of Sequences: 37866
Number of extensions: 1301314
Number of successful extensions: 4767
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 50
Number of HSP's successfully gapped in prelim test: 90
Number of HSP's that attempted gapping in prelim test: 3432
Number of HSP's gapped (non-prelim): 664
length of query: 604
length of database: 18,247,518
effective HSP length: 108
effective length of query: 496
effective length of database: 14,157,990
effective search space: 7022363040
effective search space used: 7022363040
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.