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Search of human proteins with 14589916
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens]
(1040 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens] 2094 0.0
gi|14589914 protocadherin 10 isoform 2 precursor [Homo sapiens] 1762 0.0
gi|94538350 protocadherin 17 precursor [Homo sapiens] 780 0.0
gi|157426845 protocadherin 19 isoform b [Homo sapiens] 724 0.0
gi|157426847 protocadherin 19 isoform a [Homo sapiens] 720 0.0
gi|9256600 protocadherin alpha subfamily C, 2 isoform 1 precurso... 659 0.0
gi|14165431 protocadherin alpha subfamily C, 2 isoform 2 precurs... 652 0.0
gi|14589929 protocadherin 18 precursor [Homo sapiens] 652 0.0
gi|11128023 protocadherin gamma subfamily C, 5 isoform 1 precurs... 635 0.0
gi|14277685 protocadherin gamma subfamily C, 5 isoform 2 precurs... 629 e-180
gi|8850232 protocadherin gamma subfamily A, 12 isoform 1 precurs... 617 e-176
gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens] 613 e-175
gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo sapi... 613 e-175
gi|14196457 protocadherin gamma subfamily A, 12 isoform 2 precur... 611 e-174
gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo sapi... 608 e-174
gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens] 608 e-174
gi|11128041 protocadherin gamma subfamily A, 10 isoform 1 precur... 604 e-172
gi|14196448 protocadherin gamma subfamily A, 10 isoform 2 precur... 604 e-172
gi|11056065 protocadherin gamma subfamily A, 6 isoform 1 precurs... 603 e-172
gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo sapi... 602 e-172
gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens] 602 e-172
gi|14196468 protocadherin gamma subfamily A, 4 isoform 2 precurs... 601 e-171
gi|11056026 protocadherin gamma subfamily A, 4 isoform 1 precurs... 601 e-171
gi|11056032 protocadherin gamma subfamily A, 1 isoform 1 precurs... 601 e-171
gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo sapi... 599 e-171
gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens] 599 e-171
gi|14196474 protocadherin gamma subfamily A, 6 isoform 2 precurs... 599 e-171
gi|14196459 protocadherin gamma subfamily A, 1 isoform 2 precurs... 598 e-171
gi|11056030 protocadherin gamma subfamily A, 2 isoform 1 precurs... 598 e-171
gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo sap... 597 e-170
>gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens]
Length = 1040
Score = 2094 bits (5425), Expect = 0.0
Identities = 1040/1040 (100%), Positives = 1040/1040 (100%)
Query: 1 MIVLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSR 60
MIVLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSR
Sbjct: 1 MIVLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSR 60
Query: 61 TPYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPP 120
TPYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPP
Sbjct: 61 TPYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPP 120
Query: 121 SFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRF 180
SFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRF
Sbjct: 121 SFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRF 180
Query: 181 AELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRV 240
AELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRV
Sbjct: 181 AELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRV 240
Query: 241 LDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRAREL 300
LDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRAREL
Sbjct: 241 LDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRAREL 300
Query: 301 FGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISF 360
FGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISF
Sbjct: 301 FGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISF 360
Query: 361 STVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAP 420
STVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAP
Sbjct: 361 STVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAP 420
Query: 421 LDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGA 480
LDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGA
Sbjct: 421 LDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGA 480
Query: 481 YIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFS 540
YIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFS
Sbjct: 481 YIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFS 540
Query: 541 FQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLL 600
FQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLL
Sbjct: 541 FQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLL 600
Query: 601 TRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEV 660
TRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEV
Sbjct: 601 TRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEV 660
Query: 661 RDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILII 720
RDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILII
Sbjct: 661 RDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILII 720
Query: 721 ALGSVSFIFLLAMIVLAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARARKK 780
ALGSVSFIFLLAMIVLAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARARKK
Sbjct: 721 ALGSVSFIFLLAMIVLAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARARKK 780
Query: 781 KLSKSDIMLVQSSNVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKTDLMFLKPC 840
KLSKSDIMLVQSSNVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKTDLMFLKPC
Sbjct: 781 KLSKSDIMLVQSSNVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKTDLMFLKPC 840
Query: 841 SPSRSTDTEHNPCGAIVTGYTDQQPDIISNGSILSNETKHQRAELSYLVDRPRRVNSSAF 900
SPSRSTDTEHNPCGAIVTGYTDQQPDIISNGSILSNETKHQRAELSYLVDRPRRVNSSAF
Sbjct: 841 SPSRSTDTEHNPCGAIVTGYTDQQPDIISNGSILSNETKHQRAELSYLVDRPRRVNSSAF 900
Query: 901 QEADIVSSKDSGHGDSEQGDSDHDATNRAQSAGMDLFSNCTEECKALGHSDRCWMPSFVP 960
QEADIVSSKDSGHGDSEQGDSDHDATNRAQSAGMDLFSNCTEECKALGHSDRCWMPSFVP
Sbjct: 901 QEADIVSSKDSGHGDSEQGDSDHDATNRAQSAGMDLFSNCTEECKALGHSDRCWMPSFVP 960
Query: 961 SDGRQAADYRSNLHVPGMDSVPDTEVFETPEAQPGAERSFSTFGKEKALHSTLERKELDG 1020
SDGRQAADYRSNLHVPGMDSVPDTEVFETPEAQPGAERSFSTFGKEKALHSTLERKELDG
Sbjct: 961 SDGRQAADYRSNLHVPGMDSVPDTEVFETPEAQPGAERSFSTFGKEKALHSTLERKELDG 1020
Query: 1021 LLTNTRAPYKPPYLTRKRIC 1040
LLTNTRAPYKPPYLTRKRIC
Sbjct: 1021 LLTNTRAPYKPPYLTRKRIC 1040
>gi|14589914 protocadherin 10 isoform 2 precursor [Homo sapiens]
Length = 896
Score = 1762 bits (4564), Expect = 0.0
Identities = 878/884 (99%), Positives = 881/884 (99%)
Query: 1 MIVLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSR 60
MIVLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSR
Sbjct: 1 MIVLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSR 60
Query: 61 TPYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPP 120
TPYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPP
Sbjct: 61 TPYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPP 120
Query: 121 SFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRF 180
SFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRF
Sbjct: 121 SFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRF 180
Query: 181 AELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRV 240
AELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRV
Sbjct: 181 AELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRV 240
Query: 241 LDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRAREL 300
LDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRAREL
Sbjct: 241 LDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRAREL 300
Query: 301 FGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISF 360
FGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISF
Sbjct: 301 FGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISF 360
Query: 361 STVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAP 420
STVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAP
Sbjct: 361 STVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAP 420
Query: 421 LDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGA 480
LDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGA
Sbjct: 421 LDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGA 480
Query: 481 YIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFS 540
YIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFS
Sbjct: 481 YIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFS 540
Query: 541 FQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLL 600
FQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLL
Sbjct: 541 FQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLL 600
Query: 601 TRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEV 660
TRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEV
Sbjct: 601 TRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEV 660
Query: 661 RDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILII 720
RDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILII
Sbjct: 661 RDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILII 720
Query: 721 ALGSVSFIFLLAMIVLAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARARKK 780
ALGSVSFIFLLAMIVLAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARARKK
Sbjct: 721 ALGSVSFIFLLAMIVLAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARARKK 780
Query: 781 KLSKSDIMLVQSSNVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKTDLMFLKPC 840
KLSKSDIMLVQSSNVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKTDLMFLKPC
Sbjct: 781 KLSKSDIMLVQSSNVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKTDLMFLKPC 840
Query: 841 SPSRSTDTEHNPCGAIVTGYTDQQPDIISNGSILSNETKHQRAE 884
SPSRSTDTEHNPCGAIVTGYTDQQPDIISNGSILSNE + +R +
Sbjct: 841 SPSRSTDTEHNPCGAIVTGYTDQQPDIISNGSILSNEVRLKRKD 884
>gi|94538350 protocadherin 17 precursor [Homo sapiens]
Length = 1159
Score = 780 bits (2015), Expect = 0.0
Identities = 456/1084 (42%), Positives = 646/1084 (59%), Gaps = 124/1084 (11%)
Query: 9 LLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDL----GLDITKLSARG------FQTVPN 58
LLW L+Y+V EEQ GT +GNI D GL + G ++ + N
Sbjct: 10 LLWAPALTLKNLNYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSKSGSYRVLEN 69
Query: 59 SRTPYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDN 118
S LD++ ++G+LY ++IDRE +C+ + C L LEVF N E+ +++E+ DINDN
Sbjct: 70 SAPHLLDVDADSGLLYTKQRIDRESLCRHNAKCQLSLEVFA-NDKEICMIKVEIQDINDN 128
Query: 119 PPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSY--FSLDVQTQGD 176
PSF + ++ISE+A PGTRFPL SA DPD G N LR Y +T + + F LDV+++GD
Sbjct: 129 APSFSSDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFGLDVKSRGD 188
Query: 177 GNRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALL 236
G +F ELV++K LDREQQ H VLTA+DGG PP R+ T +
Sbjct: 189 GTKFPELVIQKALDREQQNHHTLVLTALDGGE----------------PP---RSATVQI 229
Query: 237 TIRVLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPR 296
++V+DSNDN P F+ P Y V LPEN+P GT+VI LNATD DEG NGEV+YSFSS++ R
Sbjct: 230 NVKVIDSNDNSPVFEAPSYLVELPENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDR 289
Query: 297 ARELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAP 356
RELF + P+TG + V G LDYEE+ + ++ VQA+DLGPN +PAHCKV V+++D NDNAP
Sbjct: 290 VRELFSIDPKTGLIRVKGNLDYEENGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAP 349
Query: 357 EISFSTVKE-AVSEGAAPGTVVALFSVTDRDSEENGQVQCELLG---------------D 400
I F +V++ A+SE A PGTV+AL VTDRDS +NGQ+QC +LG
Sbjct: 350 SIGFVSVRQGALSEAAPPGTVIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGS 409
Query: 401 VPFRLKSSFKNYYTIVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNA 460
VPF+L+ ++ N+YT+VT+ PLDRE D Y +T+VARD G P L+++KS +++ D NDN
Sbjct: 410 VPFKLEENYDNFYTVVTDRPLDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNP 469
Query: 461 PRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINS 520
PRF++ +Y + V ENN+PG Y+ +V A D D G N ++YSIL I +S++TYVS+N
Sbjct: 470 PRFTKGLYVLQVHENNIPGEYLGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVSVNP 529
Query: 521 ENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPG 580
NG +YALRSF++EQ K F F+V A+D+G+P L NATV + ++D NDNAP IV LP
Sbjct: 530 TNGAIYALRSFNFEQTKAFEFKVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIV--LPT 587
Query: 581 RNGTPAREVLPRSAEPGYLLTRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRT 640
A +PR+A GYL++ V A+D+D GE+ RLTY IV GN+ +LF +D +GE+RT
Sbjct: 588 LQNDTAELQVPRNAGLGYLVSTVRALDSDFGESGRLTYEIVDGNDDHLFEIDPSSGEIRT 647
Query: 641 ARRVPAKRDPQRPYELVIEVRDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQ 700
P D ELV++V DHG+P LS+ A L+++ V G++ P+G
Sbjct: 648 LH--PFWEDVTPVVELVVKVTDHGKPTLSAVAKLIIRSVSGSL-PEG------------- 691
Query: 701 RPSRSGGGETSLDLTLILIIALGSVSFIFLLAMIVLAVRCQKE-KKLNIYTCLASDCCLC 759
R G + D++L LI+ L ++S I L AMI +AV+C++E K++ Y C ++
Sbjct: 692 -VPRVNGEQHHWDMSLPLIVTLSTISIILLAAMITIAVKCKRENKEIRTYNCRIAE--YS 748
Query: 760 CCCCGGGGSTCCGRQARARKKKLSKSDIMLVQSSNVPSNPAQV-PIEESGGFGSHHHNQN 818
GGG + +KKK++K+DIMLVQS N V + S +
Sbjct: 749 HPQLGGG---------KGKKKKINKNDIMLVQSEVEERNAMNVMNVVSSPSLAT--SPMY 797
Query: 819 YCYQVCLTPESAKTDLMFLKPCSPSRSTDTEHNPCGAIVTGY-TDQQPDIISNGSILSNE 877
+ YQ L S ++++M+LKP S + + H C TG T+ + SI+ +
Sbjct: 798 FDYQTRLPLSSPRSEVMYLKPASNNLTVPQGHAGCHTSFTGQGTNASETPATRMSII--Q 855
Query: 878 TKHQRAELSYLVDRPRRV-NSSAFQEADIVSSKDSGHGDSEQGDSDHDATNRAQSAGMDL 936
T + AE +Y+ R + V +SS F++ + S +DSGHGDS+Q DSD D TN+ M +
Sbjct: 856 TDNFPAEPNYMGSRQQFVQSSSTFKDPERASLRDSGHGDSDQADSDQD-TNKGSCCDMSV 914
Query: 937 FS----------------------NCTEECKALGHSDRCWMPSFVPSDGRQAADYRSNLH 974
NCT+EC+ LGHSDRCWMP F ++ + ADYR+NL
Sbjct: 915 REALKMKTTSTKSQPLEQEPEECVNCTDECRVLGHSDRCWMPQFPAANQAENADYRTNLF 974
Query: 975 VPGMDSVPDTEVFETPEAQPGAERSFSTFGKEKALHSTLERKELDGLLTNTRAPYKPPYL 1034
VP +++ +TE +ET P +++F TFGK+K H+ L+ N + PYL
Sbjct: 975 VPTVEANVETETYET--VNPTGKKTFCTFGKDKREHTI--------LIANVK-----PYL 1019
Query: 1035 TRKR 1038
KR
Sbjct: 1020 KAKR 1023
>gi|157426845 protocadherin 19 isoform b [Homo sapiens]
Length = 1100
Score = 724 bits (1869), Expect = 0.0
Identities = 432/1053 (41%), Positives = 621/1053 (58%), Gaps = 102/1053 (9%)
Query: 3 VLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDL---GLDITKLSARGFQTVPNS 59
VLLL A+LW L Y+V+EEQ GT + N+A+D G + A F+ V NS
Sbjct: 8 VLLLLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQASAFRVVSNS 67
Query: 60 RTPYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNP 119
+D+N +G+L +KIDR+ +C+QSP C++ LEV + + +E+ +++E+ D+NDN
Sbjct: 68 APHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEV-MSSSMEICVIKVEIKDLNDNA 126
Query: 120 PSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNR 179
PSFP + +EISE+A+PGTR PL+SA+DPD G+ ++ YE+TPN F L+++T+GDG+R
Sbjct: 127 PSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKTRGDGSR 186
Query: 180 FAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIR 239
FAELV+EK LDRE Q+ + + +TA+DGG PP R GT L+I+
Sbjct: 187 FAELVVEKSLDRETQSHYSFRITALDGGD----------------PP---RLGTVGLSIK 227
Query: 240 VLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARE 299
V DSNDN P F + Y VS+PENSPP T VI+LNA+DPDEG NG+VVYSF +++ R RE
Sbjct: 228 VTDSNDNNPVFSESTYAVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRE 287
Query: 300 LFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEIS 359
LF + P +G + V+G LDYEE VY++ VQAKDLGPN++PAHCKV V VLD NDN P I+
Sbjct: 288 LFQIDPHSGLVTVTGALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVIN 347
Query: 360 FSTVKE---AVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIV 416
+V VSE A PG V+AL V+DRDS NG+VQC LLG+VPFRL+ ++++ TI+
Sbjct: 348 LLSVNSELVEVSESAPPGYVIALVRVSDRDSGLNGRVQCRLLGNVPFRLQ-EYESFSTIL 406
Query: 417 TEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENN 476
+ LDRE D Y LT+ ARD G P L ++KS V ++D NDN P FS+P Y V V ENN
Sbjct: 407 VDGRLDREQHDQYNLTIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENN 466
Query: 477 VPGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQL 536
PGAY+ +VSA D D G N ++Y I+ Q++ M VFTYVSIN +G +YALRSF++EQ
Sbjct: 467 TPGAYLLSVSARDPDLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQT 526
Query: 537 KDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEP 596
K F F+V A+D G P +L NATV ++I+D NDN P I AP P NGT A +PR++
Sbjct: 527 KAFEFKVLAKDGGLP-SLQSNATVRVIILDVNDNTPVITAP-PLINGT-AEVYIPRNSGI 583
Query: 597 GYLLTRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYEL 656
GYL+T V A D D+GEN R+TY + G + F +D GE+RT R + YEL
Sbjct: 584 GYLVTVVKAEDYDEGENGRVTYDMTEG-DRGFFEIDQVNGEVRTTRTF--GESSKSSYEL 640
Query: 657 VIEVRDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTL 716
++ DHG+ LS++A +++ L A++ Q G S++L+L
Sbjct: 641 IVVAHDHGKTSLSASALVLIYL-SPALDAQESMG--------------------SVNLSL 679
Query: 717 ILIIALGSVSFIFLLAMIVLAVRCQKE-KKLNIYTCLASDCCLCCCCCGGGGSTCCGRQA 775
I IIALGS++ I + MI +A++C+++ K++ Y C ++ G Q
Sbjct: 680 IFIIALGSIAGILFVTMIFVAIKCKRDNKEIRTYNCRIAEYSY-------------GHQK 726
Query: 776 R-ARKKKLSKSDIMLVQSSNVPSNPAQVPIEESGGFGSHHHNQNY--CYQVCLTPESAKT 832
+ ++KKK+SK+DI L VP + + S + NY +Q L ++
Sbjct: 727 KSSKKKKISKNDIRL-----VPRDVEETDKMNVVSCSSLTSSLNYFDYHQQTLPLGCRRS 781
Query: 833 DLMFLKPCSPSRSTDTEHNPCGAIVTGYTDQQPDIISNGSILSNETKHQRAELSYLVDRP 892
+ FL + + + ++ QQPD+I NG L ET++ + +Y+ R
Sbjct: 782 ESTFLNVENQNTRNTSANHIYHHSFNSQGPQQPDLIINGVPLP-ETENYSFDSNYVNSRA 840
Query: 893 RRVNSSAFQEADIVSSKDSGHGDSEQGDSDHDATNR--AQSAGMDLFS------------ 938
+ SS F++ + S KDSGH +S+Q DS+HD +A D+ +
Sbjct: 841 HLIKSSTFKDLEGNSLKDSGHEESDQTDSEHDVQRSLYCDTAVNDVLNTSVTSMGSQMPD 900
Query: 939 -------NCTEECKALGHSDRCWMP-SFVPSDGRQAADYRSNLHVPGMDSVPDTEVFETP 990
+C EEC+ LGHSDRCWMP + +P + R+ + + + D E ++
Sbjct: 901 HDQNEGFHCREECRILGHSDRCWMPRNPMPIRSKSPEHVRNIIALSIEATAADVEAYD-- 958
Query: 991 EAQPGAERSFSTFGKEKALHSTLERKELDGLLT 1023
+ P +R+F+TFGK+ + H ER L G T
Sbjct: 959 DCGP-TKRTFATFGKDVSDHPAEERPTLKGKRT 990
>gi|157426847 protocadherin 19 isoform a [Homo sapiens]
Length = 1101
Score = 720 bits (1858), Expect = 0.0
Identities = 432/1054 (40%), Positives = 622/1054 (59%), Gaps = 103/1054 (9%)
Query: 3 VLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDL---GLDITKLSARGFQTVPNS 59
VLLL A+LW L Y+V+EEQ GT + N+A+D G + A F+ V NS
Sbjct: 8 VLLLLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQASAFRVVSNS 67
Query: 60 RTPYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNP 119
+D+N +G+L +KIDR+ +C+QSP C++ LEV + + +E+ +++E+ D+NDN
Sbjct: 68 APHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEV-MSSSMEICVIKVEIKDLNDNA 126
Query: 120 PSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNR 179
PSFP + +EISE+A+PGTR PL+SA+DPD G+ ++ YE+TPN F L+++T+GDG+R
Sbjct: 127 PSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKTRGDGSR 186
Query: 180 FAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIR 239
FAELV+EK LDRE Q+ + + +TA+DGG PP R GT L+I+
Sbjct: 187 FAELVVEKSLDRETQSHYSFRITALDGGD----------------PP---RLGTVGLSIK 227
Query: 240 VLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARE 299
V DSNDN P F + Y VS+PENSPP T VI+LNA+DPDEG NG+VVYSF +++ R RE
Sbjct: 228 VTDSNDNNPVFSESTYAVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRE 287
Query: 300 LFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEIS 359
LF + P +G + V+G LDYEE VY++ VQAKDLGPN++PAHCKV V VLD NDN P I+
Sbjct: 288 LFQIDPHSGLVTVTGALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVIN 347
Query: 360 FSTVKE---AVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIV 416
+V VSE A PG V+AL V+DRDS NG+VQC LLG+VPFRL+ ++++ TI+
Sbjct: 348 LLSVNSELVEVSESAPPGYVIALVRVSDRDSGLNGRVQCRLLGNVPFRLQ-EYESFSTIL 406
Query: 417 TEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENN 476
+ LDRE D Y LT+ ARD G P L ++KS V ++D NDN P FS+P Y V V ENN
Sbjct: 407 VDGRLDREQHDQYNLTIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENN 466
Query: 477 VPGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQL 536
PGAY+ +VSA D D G N ++Y I+ Q++ M VFTYVSIN +G +YALRSF++EQ
Sbjct: 467 TPGAYLLSVSARDPDLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQT 526
Query: 537 KDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEP 596
K F F+V A+D G P +L NATV ++I+D NDN P I AP P NGT A +PR++
Sbjct: 527 KAFEFKVLAKDGGLP-SLQSNATVRVIILDVNDNTPVITAP-PLINGT-AEVYIPRNSGI 583
Query: 597 GYLLTRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYEL 656
GYL+T V A D D+GEN R+TY + G + F +D GE+RT R + YEL
Sbjct: 584 GYLVTVVKAEDYDEGENGRVTYDMTEG-DRGFFEIDQVNGEVRTTRTF--GESSKSSYEL 640
Query: 657 VIEVRDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTL 716
++ DHG+ LS++A +++ L A++ Q G S++L+L
Sbjct: 641 IVVAHDHGKTSLSASALVLIYL-SPALDAQESMG--------------------SVNLSL 679
Query: 717 ILIIALGSVSFIFLLAMIVLAVRCQKE-KKLNIYTCLASDCCLCCCCCGGGGSTCCGRQA 775
I IIALGS++ I + MI +A++C+++ K++ Y C ++ G Q
Sbjct: 680 IFIIALGSIAGILFVTMIFVAIKCKRDNKEIRTYNCRIAEYSY-------------GHQK 726
Query: 776 R-ARKKKLSKSDIMLVQSSNVPSNPAQVPIEESGGFGSHHHNQNY--CYQVCLTPESAKT 832
+ ++KKK+SK+DI L VP + + S + NY +Q L ++
Sbjct: 727 KSSKKKKISKNDIRL-----VPRDVEETDKMNVVSCSSLTSSLNYFDYHQQTLPLGCRRS 781
Query: 833 DLMFLKPCSPSRSTDTEHNPCGAIVTGYTDQQPDIISNGSILSNETKHQRAELSYLVDRP 892
+ FL + + + ++ QQPD+I NG L ET++ + +Y+ R
Sbjct: 782 ESTFLNVENQNTRNTSANHIYHHSFNSQGPQQPDLIINGVPLP-ETENYSFDSNYVNSRA 840
Query: 893 RRV-NSSAFQEADIVSSKDSGHGDSEQGDSDHDATNR--AQSAGMDLFS----------- 938
+ +SS F++ + S KDSGH +S+Q DS+HD +A D+ +
Sbjct: 841 HLIKSSSTFKDLEGNSLKDSGHEESDQTDSEHDVQRSLYCDTAVNDVLNTSVTSMGSQMP 900
Query: 939 --------NCTEECKALGHSDRCWMP-SFVPSDGRQAADYRSNLHVPGMDSVPDTEVFET 989
+C EEC+ LGHSDRCWMP + +P + R+ + + + D E ++
Sbjct: 901 DHDQNEGFHCREECRILGHSDRCWMPRNPMPIRSKSPEHVRNIIALSIEATAADVEAYD- 959
Query: 990 PEAQPGAERSFSTFGKEKALHSTLERKELDGLLT 1023
+ P +R+F+TFGK+ + H ER L G T
Sbjct: 960 -DCGP-TKRTFATFGKDVSDHPAEERPTLKGKRT 991
>gi|9256600 protocadherin alpha subfamily C, 2 isoform 1 precursor
[Homo sapiens]
Length = 1007
Score = 659 bits (1700), Expect = 0.0
Identities = 398/1037 (38%), Positives = 588/1037 (56%), Gaps = 94/1037 (9%)
Query: 1 MIVLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSR 60
++ LLL LL + SQL Y+V EEQ G VGN+A LGL++ +L G + +
Sbjct: 25 LLPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGP-GCLRINHLG 83
Query: 61 TP---YLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDIND 117
P YL+L+L +G L+VNE+IDRE +C+Q P C+L LEV NP+ + VE+E+LDIND
Sbjct: 84 APSPRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDIND 143
Query: 118 NPPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDG 177
N P FP P+ +++SES PG RF +ESA DPDVG NS++ YE++P+ +F LD++ +
Sbjct: 144 NSPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQEN 203
Query: 178 NRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLT 237
++ ELVL K LDREQ A+H VLTAVDGG +P R+GTA ++
Sbjct: 204 SKVLELVLRKGLDREQAALHHLVLTAVDGG----------------IPA---RSGTAQIS 244
Query: 238 IRVLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRA 297
+RVLD+NDN PAFDQ Y V L E+SPPGTLV++LNA+DPDEG NGE+ YS SS+ S R
Sbjct: 245 VRVLDTNDNSPAFDQSTYRVQLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRE 304
Query: 298 RELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPE 357
R+LF + TG + V G LDYEE+ YQ+YVQA D GP + HCKVLV ++D NDNAPE
Sbjct: 305 RQLFSIDASTGEVRVIGGLDYEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPE 364
Query: 358 ISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVT 417
+ + + V E A P T+VA+ SV D+DS N +V L +PFRL + F N YT+V
Sbjct: 365 VVLTDLYSPVPENATPNTIVAVLSVNDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVV 423
Query: 418 EAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNV 477
PLDRE Y +TV A D G P L++ ++++V++SD+NDN P F + Y +Y+ ENN+
Sbjct: 424 SGPLDRERVAVYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNL 483
Query: 478 PGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLK 537
PG + V ATD DE NA++ YS+LE +IQG+ V +YVSINS +G LYA+ SFDYE+ +
Sbjct: 484 PGVLLCTVQATDPDEKENAEVTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFR 543
Query: 538 DFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPG 597
+F VEA+D GSP L+ T N+ +VD ND+AP I+ P N + A E++PR+A G
Sbjct: 544 EFFVTVEAQDKGSP-PLSSTVTANVYVVDMNDHAPHILYP-TSTNSSAAFEMVPRTAPAG 601
Query: 598 YLLTRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELV 657
YL+T+V A+D+D G+NA L Y + + ++++LF+++ TGE+RT R++ + + L
Sbjct: 602 YLVTKVIAMDSDSGQNAWLFYHLAQTSDLDLFKVELHTGEIRTTRKM--GDESGSTFNLT 659
Query: 658 IEVRDHGQPPLSSTATLVVQLVD--GAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLT 715
+ VRD+G+P LS++ + V +VD + P + QR +S T ++T
Sbjct: 660 VVVRDNGEPSLSASVAITVAVVDRVSKILP------------DTQRHVKS--PRTYSEIT 705
Query: 716 LILIIALGSVSFIFLLAMIVLA-VRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQ 774
L LIIAL +VSFIFLL +I+L+ ++C + YT + CC GG +
Sbjct: 706 LYLIIALSTVSFIFLLTIIILSIIKCYR------YTAYGTACC--------GGFCGVRER 751
Query: 775 ARARKKKLSKSDIMLVQSSNVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKTDL 834
+ A K + ++I + P + + +G + YCY+ CLT S
Sbjct: 752 SPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSL-----TKTYCYKACLTAGSGSDTF 806
Query: 835 MFLKPCSPSRSTDTEHNPCGA--------IVTGYTDQQPD---IISNGSILSNETKHQRA 883
MF + T P GA +TG + Q I+ N ++ NE +
Sbjct: 807 MFY-----NTGAQTGPGPSGAQAAVTDSRNLTGQSGQNAGNLIILKNEAVSQNEPRQPNP 861
Query: 884 ELSYLVDRPRRVNSSA-FQEADIVSSKDSGHGDSEQGDSDHDATNRAQSAGMDLFSNCTE 942
+ Y ++SS +EA I+ + G +Q + AT ++ +
Sbjct: 862 DWRYSASLRAGMHSSVHLEEAGILRAGPG--GPDQQWPTVSSATPEPEAGEV-------S 912
Query: 943 ECKALGHSDRCWMPSFVPSDGRQA--ADYRSNLHVPGMDSVPDTEVFETPEAQPGAERSF 1000
G + W + P + +Q+ + +PG ++ + + P + F
Sbjct: 913 PPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAI--ISIRQEPTNSQIDKSDF 970
Query: 1001 STFGKEKALHSTLERKE 1017
TFGK++ ++K+
Sbjct: 971 ITFGKKEETKKKKKKKK 987
>gi|14165431 protocadherin alpha subfamily C, 2 isoform 2 precursor
[Homo sapiens]
Length = 884
Score = 652 bits (1682), Expect = 0.0
Identities = 376/892 (42%), Positives = 532/892 (59%), Gaps = 74/892 (8%)
Query: 1 MIVLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSR 60
++ LLL LL + SQL Y+V EEQ G VGN+A LGL++ +L G + +
Sbjct: 25 LLPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGP-GCLRINHLG 83
Query: 61 TP---YLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDIND 117
P YL+L+L +G L+VNE+IDRE +C+Q P C+L LEV NP+ + VE+E+LDIND
Sbjct: 84 APSPRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDIND 143
Query: 118 NPPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDG 177
N P FP P+ +++SES PG RF +ESA DPDVG NS++ YE++P+ +F LD++ +
Sbjct: 144 NSPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQEN 203
Query: 178 NRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLT 237
++ ELVL K LDREQ A+H VLTAVDGG +P R+GTA ++
Sbjct: 204 SKVLELVLRKGLDREQAALHHLVLTAVDGG----------------IPA---RSGTAQIS 244
Query: 238 IRVLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRA 297
+RVLD+NDN PAFDQ Y V L E+SPPGTLV++LNA+DPDEG NGE+ YS SS+ S R
Sbjct: 245 VRVLDTNDNSPAFDQSTYRVQLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRE 304
Query: 298 RELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPE 357
R+LF + TG + V G LDYEE+ YQ+YVQA D GP + HCKVLV ++D NDNAPE
Sbjct: 305 RQLFSIDASTGEVRVIGGLDYEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPE 364
Query: 358 ISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVT 417
+ + + V E A P T+VA+ SV D+DS N +V L +PFRL + F N YT+V
Sbjct: 365 VVLTDLYSPVPENATPNTIVAVLSVNDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVV 423
Query: 418 EAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNV 477
PLDRE Y +TV A D G P L++ ++++V++SD+NDN P F + Y +Y+ ENN+
Sbjct: 424 SGPLDRERVAVYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNL 483
Query: 478 PGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLK 537
PG + V ATD DE NA++ YS+LE +IQG+ V +YVSINS +G LYA+ SFDYE+ +
Sbjct: 484 PGVLLCTVQATDPDEKENAEVTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFR 543
Query: 538 DFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPG 597
+F VEA+D GSP L+ T N+ +VD ND+AP I+ P N + A E++PR+A G
Sbjct: 544 EFFVTVEAQDKGSP-PLSSTVTANVYVVDMNDHAPHILYP-TSTNSSAAFEMVPRTAPAG 601
Query: 598 YLLTRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELV 657
YL+T+V A+D+D G+NA L Y + + ++++LF+++ TGE+RT R++ + + L
Sbjct: 602 YLVTKVIAMDSDSGQNAWLFYHLAQTSDLDLFKVELHTGEIRTTRKM--GDESGSTFNLT 659
Query: 658 IEVRDHGQPPLSSTATLVVQLVD--GAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLT 715
+ VRD+G+P LS++ + V +VD + P + QR +S T ++T
Sbjct: 660 VVVRDNGEPSLSASVAITVAVVDRVSKILP------------DTQRHVKS--PRTYSEIT 705
Query: 716 LILIIALGSVSFIFLLAMIVLA-VRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQ 774
L LIIAL +VSFIFLL +I+L+ ++C + YT + CC GG +
Sbjct: 706 LYLIIALSTVSFIFLLTIIILSIIKCYR------YTAYGTACC--------GGFCGVRER 751
Query: 775 ARARKKKLSKSDIMLVQSSNVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKTDL 834
+ A K + ++I + P + + +G + YCY+ CLT S
Sbjct: 752 SPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSL-----TKTYCYKACLTAGSGSDTF 806
Query: 835 MFLKPCSPSRSTDTEHNPCGAIVT-----GYTDQQPDIISNGSILSNETKHQ 881
MF + T P GA T Q N IL NE Q
Sbjct: 807 MFY-----NTGAQTGPGPSGAQAAVTDSRNLTGQSGQNAGNLIILKNEAVSQ 853
>gi|14589929 protocadherin 18 precursor [Homo sapiens]
Length = 1135
Score = 652 bits (1681), Expect = 0.0
Identities = 398/1034 (38%), Positives = 587/1034 (56%), Gaps = 121/1034 (11%)
Query: 20 LHYTVQEEQEHGTFVGNIAEDLGLDITKL---SARGFQTVPNSRTPYLDLNLETGVLYVN 76
L Y + EEQ G+ + ++ED+ + KL S F+ + +P L +N + G + +
Sbjct: 30 LKYRIYEEQRVGSVIARLSEDVADVLLKLPNPSTVRFRAMQRGNSPLLVVNEDNGEISIG 89
Query: 77 EKIDREQICKQSPSCVLHLEVFL--ENPLELFQVEIEVLDINDNPPSFPEPDLTVEISES 134
IDREQ+C+++ +C + +V L+LF +E+EVLDINDN P F + +EISES
Sbjct: 90 ATIDREQLCQKNLNCSIEFDVITLPTEHLQLFHIEVEVLDINDNSPQFSRSLIPIEISES 149
Query: 135 ATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAELVLEKPLDREQQ 194
A GTR PL+SAFDPDVG NSL Y ++ N +F+++V+T+ DG ++AEL++ + LDRE +
Sbjct: 150 AAVGTRIPLDSAFDPDVGENSLHTYSLSANDFFNIEVRTRTDGAKYAELIVVRELDRELK 209
Query: 195 AVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLDSNDNVPAFDQPV 254
+ + LTA D G+P QR+G+++L I + DSNDN PAF+Q
Sbjct: 210 SSYELQLTASD----------------MGVP---QRSGSSILKISISDSNDNSPAFEQQS 250
Query: 255 YTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGLSPRTGRLEVSG 314
Y + L ENSP GTL++ LNATDPDEG NG++VYSFSSH+SP+ E F + G L +
Sbjct: 251 YIIQLLENSPVGTLLLDLNATDPDEGANGKIVYSFSSHVSPKIMETFKIDSERGHLTLFK 310
Query: 315 ELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFSTV---KEAVS--- 368
++DYE + Y++ VQA+DLGPN++PAHCK++++V+D NDN PEI+ + + KE +S
Sbjct: 311 QVDYEITKSYEIDVQAQDLGPNSIPAHCKIIIKVVDVNDNKPEININLMSPGKEEISYIF 370
Query: 369 EGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLDREAGDS 428
EG T VAL V D+DS NG++ C+L G F+L+ +++N Y I+T A LDRE
Sbjct: 371 EGDPIDTFVALVRVQDKDSGLNGEIVCKLHGHGHFKLQKTYENNYLILTNATLDREKRSE 430
Query: 429 YTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYAVSAT 488
Y+LTV+A DRG P+LST K VQ++D+NDN P F + Y+ ++ENN PGAYI V+AT
Sbjct: 431 YSLTVIAEDRGTPSLSTVKHFTVQINDINDNPPHFQRSRYEFVISENNSPGAYITTVTAT 490
Query: 489 DRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQVEARDA 548
D D G N Q+ Y+ILE I G S+ TYV+I+ NG +YALR FD+E++ +F VEARD
Sbjct: 491 DPDLGENGQVTYTILESFILGSSITTYVTIDPSNGAIYALRIFDHEEVSQITFVVEARDG 550
Query: 549 GSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTRVAAVDA 608
GSP+ L N TV + I+D+NDN P ++ P RN T A +P+ AE G+ +TR+ A+D
Sbjct: 551 GSPKQLVSNTTVVLTIIDENDNVPVVIGPAL-RNNT-AEITIPKGAESGFHVTRIRAIDR 608
Query: 609 DDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVRDHGQPPL 668
D G NA L+ +IV GNE N+F +D R+ ++ T V P +EL + ++D G P L
Sbjct: 609 DSGVNAELSCAIVAGNEENIFIIDPRSCDIHT--NVSMDSVPYTEWELSVIIQDKGNPQL 666
Query: 669 SSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILIIALGSVSFI 728
+ L + + A + + + SLD+++I+II+LG++ +
Sbjct: 667 HTKVLLKCMIFEYAESVTS--------------TAMTSVSQASLDVSMIIIISLGAICAV 712
Query: 729 FLLAMIVLAVRCQKEKK-LNIYTCLASDCCLCCCCCGGGGSTCCGRQARARKKKLSKSDI 787
L+ M++ A RC +EKK Y C ++ + + +++ K DI
Sbjct: 713 LLVIMVLFATRCNREKKDTRSYNCRVAE-------------STYQHHPKRPSRQIHKGDI 759
Query: 788 MLVQSSN--VP------SNPAQVPIEESGGFGSHH-HNQNYCYQVCLTPESAKTDLMFLK 838
LV + N +P S+P+ P E G GS HN + +T S F
Sbjct: 760 TLVPTINGTLPIRSHHRSSPSSSPTLERGQMGSRQSHNSHQSLNSLVTISSNHVPENF-- 817
Query: 839 PCSPSRSTDTEHNPCGAIVTGYTDQQPDIISNGSILSNETKHQRAELSYLVDRPRRVNSS 898
S + H T +Q ++S + ++ ++Q S+ ++ R
Sbjct: 818 ------SLELTH------ATPAVEQVSQLLS----MLHQGQYQ-PRPSFRGNKYSRSYRY 860
Query: 899 AFQEADIVSSKDSGHGDSEQGDSDHD-----ATNRAQSAGM-DLFSN----------CTE 942
A Q+ D S KDSG GDSE GDSD+D +R G DLF CTE
Sbjct: 861 ALQDMDKFSLKDSGRGDSEAGDSDYDLGRDSPIDRLLGEGFSDLFLTDGRIPAAMRLCTE 920
Query: 943 ECKALGHSDRCWMPSFVPSDGRQAADYRSNLHVPGMDSVPDTEVFETP------EAQPG- 995
EC+ LGHSD+CWMP +PS ++DYRSN+ +PG + P + P +AQP
Sbjct: 921 ECRVLGHSDQCWMPP-LPS---PSSDYRSNMFIPG-EEFPTQPQQQHPHQSLEDDAQPAD 975
Query: 996 ---AERSFSTFGKE 1006
++SFSTFGK+
Sbjct: 976 SGEKKKSFSTFGKD 989
>gi|11128023 protocadherin gamma subfamily C, 5 isoform 1 precursor
[Homo sapiens]
Length = 944
Score = 635 bits (1638), Expect = 0.0
Identities = 385/970 (39%), Positives = 546/970 (56%), Gaps = 87/970 (8%)
Query: 16 VFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRTPYLDLNLETGVLYV 75
V QL Y+V EE E GT VGN+A+DLGL +T L +R Q Y L+L +G L V
Sbjct: 27 VSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGALAV 86
Query: 76 NEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPSFPEPDLTVEISESA 135
N+KIDRE +C S SC+L ++V E+PLEL +VE+E+LD+NDN PSF P+ + ISESA
Sbjct: 87 NQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFATPEREMRISESA 146
Query: 136 TPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAELVLEKPLDREQQA 195
G RFPL+SA DPDVGTN++ Y ++PNS+FSL+V+T DG F ELVLE+ LDRE QA
Sbjct: 147 ASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDREAQA 206
Query: 196 VHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLDSNDNVPAFDQPVY 255
H+ VLTAVDGG R+GT L+++ VLD NDN P F V
Sbjct: 207 RHQLVLTAVDGG-------------------TPARSGTTLISVIVLDINDNAPTFQSSVL 247
Query: 256 TVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGLSPRTGRLEVSGE 315
V +PEN+P GTL+++LNATDPDEG NG++ YSF H S R LFGL P +G + V G
Sbjct: 248 RVGIPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGP 307
Query: 316 LDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFSTVKEAVSEGAAPGT 375
+D+EES Y+++ +A+D G A+ HC + V V D NDNAPE+ +++ V E GT
Sbjct: 308 IDFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGT 367
Query: 376 VVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLDREAGDSYTLTVVA 435
VV LF+V DRDS NG+V ++ D+PF++K S +N+Y+++T PLDREA Y + ++A
Sbjct: 368 VVGLFNVRDRDSGRNGEVSLDISPDLPFQIKPS-ENHYSLLTSQPLDREATSHYIIELLA 426
Query: 436 RDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGAN 495
D G P+L +I++ +SDVNDNAPRF+Q +Y Y+ EN PG+ + V+A+D D G N
Sbjct: 427 SDAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDN 486
Query: 496 AQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALA 555
A+L YSI+ Q+QG ++V +N E+G ++A R+FDYE L+ V RD+GSP L
Sbjct: 487 ARLTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSP-PLH 545
Query: 556 GNATVNILIVDQNDNAPAIVAPLPG-RNGTPAREVLPRSAEPGYLLTRVAAVDADDGENA 614
N ++++ ++D+NDNAPA++ P P + P R LPRSA PG L+T+V AVDAD G NA
Sbjct: 546 ANTSLHVFVLDENDNAPAVLHPRPDWEHSAPQR--LPRSAPPGSLVTKVTAVDADAGHNA 603
Query: 615 RLTYSIV-RGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSSTAT 673
L+YS++ + LF + TGE+RTAR + D ++V+ VRD+G P LSSTAT
Sbjct: 604 WLSYSLLPQSTAPGLFLVSTHTGEVRTARAL--LEDDSDTQQVVVLVRDNGDPSLSSTAT 661
Query: 674 LVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILIIALGSVSFIFLLAM 733
+++ L D E P RS DLTL LI+AL +VS + L+
Sbjct: 662 VLLVLEDEDPEEM-----PKSSDFLIHPPERS-------DLTLYLIVALATVSLLSLVTF 709
Query: 734 IVLAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARARKKKLSKSDIMLVQSS 793
L+ +C + GGG CC RQ +S L SS
Sbjct: 710 TFLSAKCLQGNADG----------------DGGGGQCCRRQDSPSPDFYKQSSPNLQVSS 753
Query: 794 NVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKTDLMFLKPCSPSRSTDTEHNPC 853
+ +V + + +Q++CY+ C +P S +D FL+P S + T
Sbjct: 754 DGTLKYMEVTLRPT-------DSQSHCYRTCFSPASDGSDFTFLRPLSVQQPTALA---- 802
Query: 854 GAIVTGYTDQQPDII-SNGSILSNETKHQRAELSYLVDRPRRVNSSAFQEADIVSSKDSG 912
+PD I S + L ++ + + +R +S Q D D+G
Sbjct: 803 ---------LEPDAIRSRSNTLRERSQQAPPNTDWRFSQAQRPGTSGSQNGD-----DTG 848
Query: 913 HGDSEQGDSD--HDATNRAQSAGMDLFSNCTEECKALGHSDRCWMPSFVPSDGRQAADYR 970
+ Q D++ + S D S +G S R + P F + DYR
Sbjct: 849 TWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSAR-YGPQFTL---QHVPDYR 904
Query: 971 SNLHVPGMDS 980
N+++PG ++
Sbjct: 905 QNVYIPGSNA 914
>gi|14277685 protocadherin gamma subfamily C, 5 isoform 2 precursor
[Homo sapiens]
Length = 878
Score = 629 bits (1622), Expect = e-180
Identities = 358/833 (42%), Positives = 498/833 (59%), Gaps = 62/833 (7%)
Query: 16 VFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRTPYLDLNLETGVLYV 75
V QL Y+V EE E GT VGN+A+DLGL +T L +R Q Y L+L +G L V
Sbjct: 27 VSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGALAV 86
Query: 76 NEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPSFPEPDLTVEISESA 135
N+KIDRE +C S SC+L ++V E+PLEL +VE+E+LD+NDN PSF P+ + ISESA
Sbjct: 87 NQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFATPEREMRISESA 146
Query: 136 TPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAELVLEKPLDREQQA 195
G RFPL+SA DPDVGTN++ Y ++PNS+FSL+V+T DG F ELVLE+ LDRE QA
Sbjct: 147 ASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDREAQA 206
Query: 196 VHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLDSNDNVPAFDQPVY 255
H+ VLTAVDGG R+GT L+++ VLD NDN P F V
Sbjct: 207 RHQLVLTAVDGG-------------------TPARSGTTLISVIVLDINDNAPTFQSSVL 247
Query: 256 TVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGLSPRTGRLEVSGE 315
V +PEN+P GTL+++LNATDPDEG NG++ YSF H S R LFGL P +G + V G
Sbjct: 248 RVGIPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGP 307
Query: 316 LDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFSTVKEAVSEGAAPGT 375
+D+EES Y+++ +A+D G A+ HC + V V D NDNAPE+ +++ V E GT
Sbjct: 308 IDFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGT 367
Query: 376 VVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLDREAGDSYTLTVVA 435
VV LF+V DRDS NG+V ++ D+PF++K S +N+Y+++T PLDREA Y + ++A
Sbjct: 368 VVGLFNVRDRDSGRNGEVSLDISPDLPFQIKPS-ENHYSLLTSQPLDREATSHYIIELLA 426
Query: 436 RDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGAN 495
D G P+L +I++ +SDVNDNAPRF+Q +Y Y+ EN PG+ + V+A+D D G N
Sbjct: 427 SDAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDN 486
Query: 496 AQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALA 555
A+L YSI+ Q+QG ++V +N E+G ++A R+FDYE L+ V RD+GSP L
Sbjct: 487 ARLTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSP-PLH 545
Query: 556 GNATVNILIVDQNDNAPAIVAPLPG-RNGTPAREVLPRSAEPGYLLTRVAAVDADDGENA 614
N ++++ ++D+NDNAPA++ P P + P R LPRSA PG L+T+V AVDAD G NA
Sbjct: 546 ANTSLHVFVLDENDNAPAVLHPRPDWEHSAPQR--LPRSAPPGSLVTKVTAVDADAGHNA 603
Query: 615 RLTYSIV-RGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSSTAT 673
L+YS++ + LF + TGE+RTAR + D ++V+ VRD+G P LSSTAT
Sbjct: 604 WLSYSLLPQSTAPGLFLVSTHTGEVRTARAL--LEDDSDTQQVVVLVRDNGDPSLSSTAT 661
Query: 674 LVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILIIALGSVSFIFLLAM 733
+++ L D E P RS DLTL LI+AL +VS + L+
Sbjct: 662 VLLVLEDEDPEEM-----PKSSDFLIHPPERS-------DLTLYLIVALATVSLLSLVTF 709
Query: 734 IVLAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARARKKKLSKSDIMLVQSS 793
L+ +C + GGG CC RQ +S L SS
Sbjct: 710 TFLSAKCLQGNADG----------------DGGGGQCCRRQDSPSPDFYKQSSPNLQVSS 753
Query: 794 NVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKTDLMFLKPCSPSRST 846
+ +V + + +Q++CY+ C +P S +D FL+P S + T
Sbjct: 754 DGTLKYMEVTLRPT-------DSQSHCYRTCFSPASDGSDFTFLRPLSVQQPT 799
>gi|8850232 protocadherin gamma subfamily A, 12 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 617 bits (1592), Expect = e-176
Identities = 381/982 (38%), Positives = 550/982 (56%), Gaps = 103/982 (10%)
Query: 5 LLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRTPYL 64
+L LW E +Q+ Y+V EE E G+ VG+I+ DLGL+ +L+ RG + +P RT
Sbjct: 18 ILLGTLW--ETGCTQIRYSVPEELEKGSRVGDISRDLGLEPRELAERGVRIIPRGRTQLF 75
Query: 65 DLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPSFPE 124
LN +G L +IDRE++C + C L+L++ +E+ ++++ VE+EV DINDN P F E
Sbjct: 76 ALNPRSGSLVTAGRIDREELCMGAIKCQLNLDILMEDKVKIYGVEVEVRDINDNAPYFRE 135
Query: 125 PDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAELV 184
+L ++ISE+A RFPL A+DPD+G NSL+ YE++PN++FSL VQ DG+++ ELV
Sbjct: 136 SELEIKISENAATEMRFPLPHAWDPDIGKNSLQSYELSPNTHFSLIVQNGADGSKYPELV 195
Query: 185 LEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLDSN 244
L++ LDRE++A H VLTA DGG RTGTA + + VLD+N
Sbjct: 196 LKRALDREEKAAHHLVLTASDGG-------------------DPVRTGTARIRVMVLDAN 236
Query: 245 DNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGLS 304
DN PAF QP Y S+PEN GT ++ +NATDPDEG N EV YSF ++ +A ++F L
Sbjct: 237 DNAPAFAQPEYRASVPENLALGTQLLVVNATDPDEGVNAEVRYSF-RYVDDKAAQVFKLD 295
Query: 305 PRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFSTVK 364
+G + GELD+EES YQ+ VQA D A KVL+ VLD NDNAPE+ +++
Sbjct: 296 CNSGTISTIGELDHEESGFYQMEVQAMDNA--GYSARAKVLITVLDVNDNAPEVVLTSLA 353
Query: 365 EAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLDRE 424
+V E + GT++AL +V D+DSEENGQV C + G++PF+L+ S+ NYY++VT+ LDRE
Sbjct: 354 SSVPENSPRGTLIALLNVNDQDSEENGQVICFIQGNLPFKLEKSYGNYYSLVTDIVLDRE 413
Query: 425 AGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYA 484
SY +TV A DRG P LST I + V+D NDN P F Q Y Y+ ENN G + +
Sbjct: 414 QVPSYNITVTATDRGTPPLSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGVSLVS 473
Query: 485 VSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQVE 544
V+A D D NAQ+ YS+ E IQG S+ +YVSINS+ G LYAL SFDYEQ +D +V
Sbjct: 474 VTAHDPDCEENAQITYSLAENTIQGASLSSYVSINSDTGVLYALSSFDYEQFRDLQVKVM 533
Query: 545 ARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTRVA 604
ARD G P L+ N ++++ ++DQNDNAP I+ P +G+ E+ PRSAEPGYL+T+V
Sbjct: 534 ARDNGHP-PLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVV 592
Query: 605 AVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVRDHG 664
AVD D G+NA L+Y +++ +E LF + TGE+RTAR + RD + LV+ V+DHG
Sbjct: 593 AVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARAL-LDRDALK-QSLVVAVQDHG 650
Query: 665 QPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILIIALGS 724
QPPLS+T TL V + D + GS + P+ S ETS DLTL L++A+ +
Sbjct: 651 QPPLSATVTLTVAVADSIPQVLADLGS-------LESPANS---ETS-DLTLYLVVAVAA 699
Query: 725 VSFIFLLAMIVLAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARARKKKLSK 784
VS +FL +I+L R ++ K
Sbjct: 700 VSCVFLAFVILLLA--------------------------------------LRLRRWHK 721
Query: 785 SDIMLVQSSNVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKTDLMFLKPCSPSR 844
S ++ + PA + G G Q Y ++V LT +S K+ L+F +P
Sbjct: 722 SRLLQASGGGLTGAPASHFV---GVDGVQAFLQTYSHEVSLTTDSRKSHLIFPQPNYADM 778
Query: 845 STDTEHNPCGAIVTGYTDQQPDIISNGSILSNET----KHQRAELSYLVDRPRRVNSSAF 900
E + +P ++S S+ S ++ + + + +R +S
Sbjct: 779 LVSQE---------SFEKSEPLLLSGDSVFSKDSHGLIEQAPPNTDWRFSQAQRPGTSGS 829
Query: 901 QEADIVSSKDSGHGDSEQGDSD--HDATNRAQSAGMDLFSNCTEECKALGHSDRCWMPSF 958
Q D D+G + Q D++ + S D S +G S R + P F
Sbjct: 830 QNGD-----DTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSAR-YGPQF 883
Query: 959 VPSDGRQAADYRSNLHVPGMDS 980
+ DYR N+++PG ++
Sbjct: 884 TL---QHVPDYRQNVYIPGSNA 902
>gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens]
Length = 936
Score = 613 bits (1580), Expect = e-175
Identities = 330/800 (41%), Positives = 485/800 (60%), Gaps = 36/800 (4%)
Query: 3 VLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRTP 62
+LLL+ LL + QLHY++ EE +HGTFVG IA+DLGL++ +L R F+ R
Sbjct: 13 LLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGD 72
Query: 63 YLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPSF 122
L++NL+ G+L+VN +IDRE++C++ C +HLEV ++ PL++F VE+ V DINDNPP F
Sbjct: 73 LLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAVKDINDNPPRF 132
Query: 123 PEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAE 182
+ + I ES P +RFPLE A D D+G N+ Y + PN YF LDV+T + F E
Sbjct: 133 SRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVKTNEEETNFLE 192
Query: 183 LVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLD 242
LVL K LDRE+ HR ++ A DGG + + TGT L I VLD
Sbjct: 193 LVLRKSLDREETQEHRLLVIATDGG-------------------KPELTGTVQLLINVLD 233
Query: 243 SNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFG 302
+NDN P FD+ +Y V L EN+P GTLVI+LNA+D DEG N E+VY FS+ + + F
Sbjct: 234 ANDNAPEFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFI 293
Query: 303 LSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFST 362
++ TG ++V+GELDYE+ Y++ + A D + HCKV+V++LD NDN PE++ +T
Sbjct: 294 INSNTGEIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITT 353
Query: 363 VKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLD 422
+ V E A TV+AL SV+DRDS NGQV C L+ VPF+L S+FKNYY++V ++ LD
Sbjct: 354 LFLPVKEDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALD 413
Query: 423 REAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYI 482
RE+ Y L V ARD G P+L + S+ V+V+DVNDNAP F+QP Y V+V ENN PG +I
Sbjct: 414 RESVSVYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHI 473
Query: 483 YAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQ 542
+ VSA D D NA ++YS++E ++ + +YVS+++E+G +YAL+ D+E+++ FQ
Sbjct: 474 FTVSARDADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQ 533
Query: 543 VEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTR 602
V ARDAG P L N T+ + ++D+NDNAPA++ P G G E++PRS G+++ +
Sbjct: 534 VSARDAGVP-PLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAK 592
Query: 603 VAAVDADDGENARLTYSI--VRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEV 660
V AVD D G NA L+Y + G+ FR+ TGE+ T R + P+ + L++ V
Sbjct: 593 VRAVDPDSGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPR--HRLLVLV 650
Query: 661 RDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILII 720
+DHG+PPL++TAT++V LV+ P+ + G G +D+ + LII
Sbjct: 651 KDHGEPPLTATATVLVSLVESGQAPKASSRASAGAVGPE---------AALVDVNVYLII 701
Query: 721 ALGSVSFIFLLAMIV-LAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARARK 779
A+ +VS + +L +++ A+RC + + C L C G S R+ R
Sbjct: 702 AICAVSSLLVLTLLLYTALRCSAQPTEAV--CTRGKPTLLCSSAVGSWSYSQQRRQRVCS 759
Query: 780 KKLSKSDIMLVQSSNVPSNP 799
+ ++ S ++P P
Sbjct: 760 GEAPPKTDLMAFSPSLPQGP 779
>gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo
sapiens]
Length = 816
Score = 613 bits (1580), Expect = e-175
Identities = 330/800 (41%), Positives = 485/800 (60%), Gaps = 36/800 (4%)
Query: 3 VLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRTP 62
+LLL+ LL + QLHY++ EE +HGTFVG IA+DLGL++ +L R F+ R
Sbjct: 13 LLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGD 72
Query: 63 YLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPSF 122
L++NL+ G+L+VN +IDRE++C++ C +HLEV ++ PL++F VE+ V DINDNPP F
Sbjct: 73 LLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAVKDINDNPPRF 132
Query: 123 PEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAE 182
+ + I ES P +RFPLE A D D+G N+ Y + PN YF LDV+T + F E
Sbjct: 133 SRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVKTNEEETNFLE 192
Query: 183 LVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLD 242
LVL K LDRE+ HR ++ A DGG + + TGT L I VLD
Sbjct: 193 LVLRKSLDREETQEHRLLVIATDGG-------------------KPELTGTVQLLINVLD 233
Query: 243 SNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFG 302
+NDN P FD+ +Y V L EN+P GTLVI+LNA+D DEG N E+VY FS+ + + F
Sbjct: 234 ANDNAPEFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFI 293
Query: 303 LSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFST 362
++ TG ++V+GELDYE+ Y++ + A D + HCKV+V++LD NDN PE++ +T
Sbjct: 294 INSNTGEIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITT 353
Query: 363 VKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLD 422
+ V E A TV+AL SV+DRDS NGQV C L+ VPF+L S+FKNYY++V ++ LD
Sbjct: 354 LFLPVKEDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALD 413
Query: 423 REAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYI 482
RE+ Y L V ARD G P+L + S+ V+V+DVNDNAP F+QP Y V+V ENN PG +I
Sbjct: 414 RESVSVYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHI 473
Query: 483 YAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQ 542
+ VSA D D NA ++YS++E ++ + +YVS+++E+G +YAL+ D+E+++ FQ
Sbjct: 474 FTVSARDADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQ 533
Query: 543 VEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTR 602
V ARDAG P L N T+ + ++D+NDNAPA++ P G G E++PRS G+++ +
Sbjct: 534 VSARDAGVP-PLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAK 592
Query: 603 VAAVDADDGENARLTYSI--VRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEV 660
V AVD D G NA L+Y + G+ FR+ TGE+ T R + P+ + L++ V
Sbjct: 593 VRAVDPDSGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPR--HRLLVLV 650
Query: 661 RDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILII 720
+DHG+PPL++TAT++V LV+ P+ + G G +D+ + LII
Sbjct: 651 KDHGEPPLTATATVLVSLVESGQAPKASSRASAGAVGPE---------AALVDVNVYLII 701
Query: 721 ALGSVSFIFLLAMIV-LAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARARK 779
A+ +VS + +L +++ A+RC + + C L C G S R+ R
Sbjct: 702 AICAVSSLLVLTLLLYTALRCSAQPTEAV--CTRGKPTLLCSSAVGSWSYSQQRRQRVCS 759
Query: 780 KKLSKSDIMLVQSSNVPSNP 799
+ ++ S ++P P
Sbjct: 760 GEAPPKTDLMAFSPSLPQGP 779
>gi|14196457 protocadherin gamma subfamily A, 12 isoform 2 precursor
[Homo sapiens]
Length = 820
Score = 611 bits (1576), Expect = e-174
Identities = 362/882 (41%), Positives = 514/882 (58%), Gaps = 89/882 (10%)
Query: 5 LLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRTPYL 64
+L LW E +Q+ Y+V EE E G+ VG+I+ DLGL+ +L+ RG + +P RT
Sbjct: 18 ILLGTLW--ETGCTQIRYSVPEELEKGSRVGDISRDLGLEPRELAERGVRIIPRGRTQLF 75
Query: 65 DLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPSFPE 124
LN +G L +IDRE++C + C L+L++ +E+ ++++ VE+EV DINDN P F E
Sbjct: 76 ALNPRSGSLVTAGRIDREELCMGAIKCQLNLDILMEDKVKIYGVEVEVRDINDNAPYFRE 135
Query: 125 PDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAELV 184
+L ++ISE+A RFPL A+DPD+G NSL+ YE++PN++FSL VQ DG+++ ELV
Sbjct: 136 SELEIKISENAATEMRFPLPHAWDPDIGKNSLQSYELSPNTHFSLIVQNGADGSKYPELV 195
Query: 185 LEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLDSN 244
L++ LDRE++A H VLTA DGG RTGTA + + VLD+N
Sbjct: 196 LKRALDREEKAAHHLVLTASDGG-------------------DPVRTGTARIRVMVLDAN 236
Query: 245 DNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGLS 304
DN PAF QP Y S+PEN GT ++ +NATDPDEG N EV YSF ++ +A ++F L
Sbjct: 237 DNAPAFAQPEYRASVPENLALGTQLLVVNATDPDEGVNAEVRYSFR-YVDDKAAQVFKLD 295
Query: 305 PRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFSTVK 364
+G + GELD+EES YQ+ VQA D A KVL+ VLD NDNAPE+ +++
Sbjct: 296 CNSGTISTIGELDHEESGFYQMEVQAMDNA--GYSARAKVLITVLDVNDNAPEVVLTSLA 353
Query: 365 EAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLDRE 424
+V E + GT++AL +V D+DSEENGQV C + G++PF+L+ S+ NYY++VT+ LDRE
Sbjct: 354 SSVPENSPRGTLIALLNVNDQDSEENGQVICFIQGNLPFKLEKSYGNYYSLVTDIVLDRE 413
Query: 425 AGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYA 484
SY +TV A DRG P LST I + V+D NDN P F Q Y Y+ ENN G + +
Sbjct: 414 QVPSYNITVTATDRGTPPLSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGVSLVS 473
Query: 485 VSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQVE 544
V+A D D NAQ+ YS+ E IQG S+ +YVSINS+ G LYAL SFDYEQ +D +V
Sbjct: 474 VTAHDPDCEENAQITYSLAENTIQGASLSSYVSINSDTGVLYALSSFDYEQFRDLQVKVM 533
Query: 545 ARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTRVA 604
ARD G P L+ N ++++ ++DQNDNAP I+ P +G+ E+ PRSAEPGYL+T+V
Sbjct: 534 ARDNGHP-PLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVV 592
Query: 605 AVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVRDHG 664
AVD D G+NA L+Y +++ +E LF + TGE+RTAR + RD + LV+ V+DHG
Sbjct: 593 AVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARAL-LDRDALK-QSLVVAVQDHG 650
Query: 665 QPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILIIALGS 724
QPPLS+T TL V + D + GS + P+ S ETS DLTL L++A+ +
Sbjct: 651 QPPLSATVTLTVAVADSIPQVLADLGS-------LESPANS---ETS-DLTLYLVVAVAA 699
Query: 725 VSFIFLLAMIVLAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARARKKKLSK 784
VS +FL +I+L R ++ K
Sbjct: 700 VSCVFLAFVILLLA--------------------------------------LRLRRWHK 721
Query: 785 SDIMLVQSSNVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKTDLMFLKPCSPSR 844
S ++ + PA + G G Q Y ++V LT +S K+ L+F +P
Sbjct: 722 SRLLQASGGGLTGAPASHFV---GVDGVQAFLQTYSHEVSLTTDSRKSHLIFPQPNYADM 778
Query: 845 STDTEHNPCGAIVTGYTDQQPDIISNGSILSNETKHQRAELS 886
E + +P ++S S+ S ++ H E+S
Sbjct: 779 LVSQE---------SFEKSEPLLLSGDSVFSKDS-HGLIEVS 810
>gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo
sapiens]
Length = 789
Score = 608 bits (1568), Expect = e-174
Identities = 339/802 (42%), Positives = 488/802 (60%), Gaps = 38/802 (4%)
Query: 3 VLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRTP 62
+LL +L E QLHY+V EE +HG FVG IA+DLGL++ +L R F+ V R
Sbjct: 14 LLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCKFRGD 73
Query: 63 YLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPSF 122
L++NL+ G+L+VN +IDRE++C +S C +HLEV +E PL++F V++EV DINDNPP F
Sbjct: 74 LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDNPPVF 133
Query: 123 PEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAE 182
P + I+ES +RFPLE A D D+G N+L Y ++PN YF LDV T +
Sbjct: 134 PATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLG 193
Query: 183 LVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLD 242
LVL K LDRE+ +LTA DGG + + TGT L I VLD
Sbjct: 194 LVLRKLLDREETPELHLLLTATDGG-------------------KPELTGTVQLLITVLD 234
Query: 243 SNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFG 302
+NDN P FD+ +YTV LPEN GTLVI NA+D DEG NG+++YSFSS +SP + F
Sbjct: 235 NNDNAPVFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFH 294
Query: 303 LSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFST 362
+ P +G + V G +D+EES +++ V+A D G + HC VLV V+D NDNAP+++ ++
Sbjct: 295 MDPLSGAITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTS 354
Query: 363 VKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLD 422
+ + E A PGTV+ L SV DRD NGQV C L VPF+L S+FKNYY++V ++ LD
Sbjct: 355 LSLPIPEDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALD 414
Query: 423 REAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYI 482
RE+ +Y L V ARD G P+L + S+ V+V+DVNDNAP F+QP Y V+V ENN PG +I
Sbjct: 415 RESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHI 474
Query: 483 YAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQ 542
+ VSA D D NA ++YS++E ++ ++ +YVS+++E+G +YAL+ D+E+L+ FQ
Sbjct: 475 FTVSAGDADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQ 534
Query: 543 VEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTR 602
V ARDAG P L N T+ + ++D+NDNAPA++AP G G RE++PRS G+++ +
Sbjct: 535 VSARDAGVP-PLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAK 593
Query: 603 VAAVDADDGENARLTYSI--VRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEV 660
V AVDAD G NA L+Y + V FR+ TGE+ T R + P+ + L++ V
Sbjct: 594 VRAVDADSGYNAWLSYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPR--HRLLVLV 651
Query: 661 RDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSL-DLTLILI 719
+DHG+P L++TAT++V LV+ P+ + G G ET L D+ + LI
Sbjct: 652 KDHGEPSLTATATVLVSLVESGQAPKASSRASLG----------IAGPETELVDVNVYLI 701
Query: 720 IALGSVSFIFLLAMIV-LAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARAR 778
IA+ +VS + +L +++ A+RC + L +C G + RQ
Sbjct: 702 IAICAVSSLLVLTLLLYTALRCSAPSSEGACS-LVKPTLVCSSAVGSWSFSQQRRQRVCS 760
Query: 779 KKKLSKSDIMLVQSSNVPSNPA 800
+ K+D+M S ++P P+
Sbjct: 761 GEGPPKTDLMAF-SPSLPQGPS 781
>gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens]
Length = 937
Score = 608 bits (1568), Expect = e-174
Identities = 339/802 (42%), Positives = 488/802 (60%), Gaps = 38/802 (4%)
Query: 3 VLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRTP 62
+LL +L E QLHY+V EE +HG FVG IA+DLGL++ +L R F+ V R
Sbjct: 14 LLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCKFRGD 73
Query: 63 YLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPSF 122
L++NL+ G+L+VN +IDRE++C +S C +HLEV +E PL++F V++EV DINDNPP F
Sbjct: 74 LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDNPPVF 133
Query: 123 PEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAE 182
P + I+ES +RFPLE A D D+G N+L Y ++PN YF LDV T +
Sbjct: 134 PATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLG 193
Query: 183 LVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLD 242
LVL K LDRE+ +LTA DGG + + TGT L I VLD
Sbjct: 194 LVLRKLLDREETPELHLLLTATDGG-------------------KPELTGTVQLLITVLD 234
Query: 243 SNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFG 302
+NDN P FD+ +YTV LPEN GTLVI NA+D DEG NG+++YSFSS +SP + F
Sbjct: 235 NNDNAPVFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFH 294
Query: 303 LSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFST 362
+ P +G + V G +D+EES +++ V+A D G + HC VLV V+D NDNAP+++ ++
Sbjct: 295 MDPLSGAITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTS 354
Query: 363 VKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLD 422
+ + E A PGTV+ L SV DRD NGQV C L VPF+L S+FKNYY++V ++ LD
Sbjct: 355 LSLPIPEDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALD 414
Query: 423 REAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYI 482
RE+ +Y L V ARD G P+L + S+ V+V+DVNDNAP F+QP Y V+V ENN PG +I
Sbjct: 415 RESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHI 474
Query: 483 YAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQ 542
+ VSA D D NA ++YS++E ++ ++ +YVS+++E+G +YAL+ D+E+L+ FQ
Sbjct: 475 FTVSAGDADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQ 534
Query: 543 VEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTR 602
V ARDAG P L N T+ + ++D+NDNAPA++AP G G RE++PRS G+++ +
Sbjct: 535 VSARDAGVP-PLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAK 593
Query: 603 VAAVDADDGENARLTYSI--VRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEV 660
V AVDAD G NA L+Y + V FR+ TGE+ T R + P+ + L++ V
Sbjct: 594 VRAVDADSGYNAWLSYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPR--HRLLVLV 651
Query: 661 RDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSL-DLTLILI 719
+DHG+P L++TAT++V LV+ P+ + G G ET L D+ + LI
Sbjct: 652 KDHGEPSLTATATVLVSLVESGQAPKASSRASLG----------IAGPETELVDVNVYLI 701
Query: 720 IALGSVSFIFLLAMIV-LAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARAR 778
IA+ +VS + +L +++ A+RC + L +C G + RQ
Sbjct: 702 IAICAVSSLLVLTLLLYTALRCSAPSSEGACS-LVKPTLVCSSAVGSWSFSQQRRQRVCS 760
Query: 779 KKKLSKSDIMLVQSSNVPSNPA 800
+ K+D+M S ++P P+
Sbjct: 761 GEGPPKTDLMAF-SPSLPQGPS 781
>gi|11128041 protocadherin gamma subfamily A, 10 isoform 1 precursor
[Homo sapiens]
Length = 936
Score = 604 bits (1558), Expect = e-172
Identities = 334/736 (45%), Positives = 465/736 (63%), Gaps = 38/736 (5%)
Query: 1 MIVLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSR 60
+++ L F + W E Q+ Y++ EE E G+FVGNI++DLGL +L+ RG + V R
Sbjct: 18 VLLCLFFGIPW--EAGARQISYSIPEELEKGSFVGNISKDLGLAPRELAERGVRIVSRGR 75
Query: 61 TPYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPP 120
T LN +G L +IDRE++C QS CV+ + +E+ ++LF +EIEV DINDN P
Sbjct: 76 TQLFSLNPRSGSLITAGRIDREELCAQSARCVVSFNILVEDRVKLFGIEIEVTDINDNAP 135
Query: 121 SFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRF 180
F +L V+I+E+ G RFPL A DPDVG NSL+ Y+++PN +FSL VQ++ +G ++
Sbjct: 136 KFQAENLDVKINENVAAGMRFPLPEAIDPDVGVNSLQSYQLSPNKHFSLRVQSRANGVKY 195
Query: 181 AELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRV 240
ELVLE LDRE++A+H VLTA DGG R+GT L+++ V
Sbjct: 196 PELVLEHSLDREEEAIHHLVLTASDGG-------------------DPLRSGTVLVSVTV 236
Query: 241 LDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRAREL 300
D+NDN P F P Y VS+PEN P GT ++ + ATD DEG NGEV YSF + +
Sbjct: 237 FDANDNAPVFTLPEYRVSVPENLPVGTQLLTVTATDRDEGANGEVTYSFRKLPDTQLLK- 295
Query: 301 FGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISF 360
F L+ TG +++S LDYEE+ Y++ +QA+D G A A KVL+ V D NDN+PE++
Sbjct: 296 FQLNKYTGEIKISENLDYEETGFYEIEIQAEDGG--AYLATAKVLITVEDVNDNSPELTI 353
Query: 361 STVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAP 420
+++ V+E + GTVVAL +V D DSE+NGQV C +L +PF+L+ S +YY +V
Sbjct: 354 TSLFSPVTEDSPLGTVVALLNVHDLDSEQNGQVTCSILAYLPFKLEKSIDSYYRLVIHRA 413
Query: 421 LDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGA 480
LDRE SY +TV A D G P LST +QV+D+NDN P FSQ Y Y+ ENN GA
Sbjct: 414 LDREQVSSYNITVTATDGGSPPLSTEAHFMLQVADINDNPPTFSQVSYFTYIPENNARGA 473
Query: 481 YIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFS 540
I++V+A D D NAQ+ YS+ E IQG+ + +Y+SINS+ G LYALRSFDYEQ +
Sbjct: 474 SIFSVTALDPDSKENAQIIYSLAEDTIQGVPLSSYISINSDTGVLYALRSFDYEQFHELQ 533
Query: 541 FQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLL 600
QV A D+G P L+ N ++++ ++DQNDNAP I+ P +G+ E+ PRSAEPGYL+
Sbjct: 534 MQVTASDSGDP-PLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLV 592
Query: 601 TRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEV 660
T+V AVD D G+NA L+Y +++ +E LF + TGE+RTAR + RD + LV+ V
Sbjct: 593 TKVVAVDRDSGQNAWLSYRLLKASEPGLFAVGEHTGEVRTARAL-LDRDALK-QSLVVAV 650
Query: 661 RDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILII 720
+DHGQPPLS+T TL V + D + GS + P+ S ETS DLTL L++
Sbjct: 651 QDHGQPPLSATVTLTVAVADSIPQVLADLGS-------FESPANS---ETS-DLTLYLVV 699
Query: 721 ALGSVSFIFLLAMIVL 736
A+ +VS +FL +IVL
Sbjct: 700 AVAAVSCVFLAFVIVL 715
>gi|14196448 protocadherin gamma subfamily A, 10 isoform 2 precursor
[Homo sapiens]
Length = 850
Score = 604 bits (1558), Expect = e-172
Identities = 334/736 (45%), Positives = 465/736 (63%), Gaps = 38/736 (5%)
Query: 1 MIVLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSR 60
+++ L F + W E Q+ Y++ EE E G+FVGNI++DLGL +L+ RG + V R
Sbjct: 18 VLLCLFFGIPW--EAGARQISYSIPEELEKGSFVGNISKDLGLAPRELAERGVRIVSRGR 75
Query: 61 TPYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPP 120
T LN +G L +IDRE++C QS CV+ + +E+ ++LF +EIEV DINDN P
Sbjct: 76 TQLFSLNPRSGSLITAGRIDREELCAQSARCVVSFNILVEDRVKLFGIEIEVTDINDNAP 135
Query: 121 SFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRF 180
F +L V+I+E+ G RFPL A DPDVG NSL+ Y+++PN +FSL VQ++ +G ++
Sbjct: 136 KFQAENLDVKINENVAAGMRFPLPEAIDPDVGVNSLQSYQLSPNKHFSLRVQSRANGVKY 195
Query: 181 AELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRV 240
ELVLE LDRE++A+H VLTA DGG R+GT L+++ V
Sbjct: 196 PELVLEHSLDREEEAIHHLVLTASDGG-------------------DPLRSGTVLVSVTV 236
Query: 241 LDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRAREL 300
D+NDN P F P Y VS+PEN P GT ++ + ATD DEG NGEV YSF + +
Sbjct: 237 FDANDNAPVFTLPEYRVSVPENLPVGTQLLTVTATDRDEGANGEVTYSFRKLPDTQLLK- 295
Query: 301 FGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISF 360
F L+ TG +++S LDYEE+ Y++ +QA+D G A A KVL+ V D NDN+PE++
Sbjct: 296 FQLNKYTGEIKISENLDYEETGFYEIEIQAEDGG--AYLATAKVLITVEDVNDNSPELTI 353
Query: 361 STVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAP 420
+++ V+E + GTVVAL +V D DSE+NGQV C +L +PF+L+ S +YY +V
Sbjct: 354 TSLFSPVTEDSPLGTVVALLNVHDLDSEQNGQVTCSILAYLPFKLEKSIDSYYRLVIHRA 413
Query: 421 LDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGA 480
LDRE SY +TV A D G P LST +QV+D+NDN P FSQ Y Y+ ENN GA
Sbjct: 414 LDREQVSSYNITVTATDGGSPPLSTEAHFMLQVADINDNPPTFSQVSYFTYIPENNARGA 473
Query: 481 YIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFS 540
I++V+A D D NAQ+ YS+ E IQG+ + +Y+SINS+ G LYALRSFDYEQ +
Sbjct: 474 SIFSVTALDPDSKENAQIIYSLAEDTIQGVPLSSYISINSDTGVLYALRSFDYEQFHELQ 533
Query: 541 FQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLL 600
QV A D+G P L+ N ++++ ++DQNDNAP I+ P +G+ E+ PRSAEPGYL+
Sbjct: 534 MQVTASDSGDP-PLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLV 592
Query: 601 TRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEV 660
T+V AVD D G+NA L+Y +++ +E LF + TGE+RTAR + RD + LV+ V
Sbjct: 593 TKVVAVDRDSGQNAWLSYRLLKASEPGLFAVGEHTGEVRTARAL-LDRDALK-QSLVVAV 650
Query: 661 RDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILII 720
+DHGQPPLS+T TL V + D + GS + P+ S ETS DLTL L++
Sbjct: 651 QDHGQPPLSATVTLTVAVADSIPQVLADLGS-------FESPANS---ETS-DLTLYLVV 699
Query: 721 ALGSVSFIFLLAMIVL 736
A+ +VS +FL +IVL
Sbjct: 700 AVAAVSCVFLAFVIVL 715
>gi|11056065 protocadherin gamma subfamily A, 6 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 603 bits (1555), Expect = e-172
Identities = 381/998 (38%), Positives = 545/998 (54%), Gaps = 127/998 (12%)
Query: 1 MIVLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSR 60
+++L L LW +Q+ Y++ EE E G+FVGNI +DLGL+ +L+ G + V R
Sbjct: 14 VLLLTLLGTLWGAAA--AQIRYSIPEELEKGSFVGNIVKDLGLEPQELAEHGVRIVSRGR 71
Query: 61 TPYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPP 120
LN G L +IDRE++C QSP C++ + +E+ L L+ VE+E++DINDN P
Sbjct: 72 MQLFSLNPRNGSLVTAGRIDREELCAQSPRCLVSFNILVEDKLNLYPVEVEIVDINDNTP 131
Query: 121 SFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRF 180
F + +L V+I E+A P +RFPL +DPDVG NSL+ ++++ NS+FS+DVQ++ G ++
Sbjct: 132 RFLKEELEVKILENAAPSSRFPLMEVYDPDVGMNSLQGFKLSGNSHFSVDVQSEAHGPKY 191
Query: 181 AELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRV 240
ELVLE LDRE +AV+R VLTA+DGG R+ A + + V
Sbjct: 192 PELVLEGTLDREGEAVYRLVLTAMDGG-------------------DPVRSSVAQILVTV 232
Query: 241 LDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRAREL 300
LD NDN P F QPVY VS+PEN P GT V+ + ATD DEG +GEV YSF I+ + ++
Sbjct: 233 LDVNDNTPMFTQPVYRVSVPENLPVGTPVLAVTATDQDEGVHGEVTYSFVK-ITEKISQI 291
Query: 301 FGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISF 360
F L+ TG + S LDYE+S Y++ V+A+D GP + KVL+ +LD NDN PE+
Sbjct: 292 FCLNVLTGEISTSANLDYEDSSFYELGVEARD-GPG-LRDRAKVLITILDVNDNVPEVVV 349
Query: 361 STVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAP 420
++ ++E A PGTV+ALF V DRDS NG V C + +PF L+ S NYY +VT A
Sbjct: 350 TSGSRTIAESAPPGTVIALFQVFDRDSGLNGLVTCSIPRSLPFELEKSVGNYYRLVTNAA 409
Query: 421 LDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGA 480
LDRE Y +TV A D+G P LST I + V+D NDN P F Y VYV ENN GA
Sbjct: 410 LDREEVFLYNITVTATDKGTPPLSTETIISLNVADTNDNPPTFPHSSYSVYVLENNPRGA 469
Query: 481 YIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFS 540
I++V+A D D NAQ++YS+ E +QG + +YVSINS+ G LYALRSFDYEQL+D
Sbjct: 470 SIFSVNALDPDVDQNAQVSYSLAEDTLQGAPLSSYVSINSDTGILYALRSFDYEQLRDLQ 529
Query: 541 FQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLL 600
V A D+G P L+ N ++++ ++DQNDNAP I+ P +G+ E+ PRSAEPGYL+
Sbjct: 530 LWVTASDSGDP-PLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLV 588
Query: 601 TRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEV 660
T+V AVD D G+NA L+Y +++ +E LF + TGE+RTAR + RD + LV+ V
Sbjct: 589 TKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARAL-LDRDALK-QSLVVAV 646
Query: 661 RDHGQPPLSSTATLVVQLVD---------GAVEPQGGGGSGGGGSGEHQRPSRSGGGETS 711
+DHGQPPLS+T TL V + D G++EP +P+ S
Sbjct: 647 QDHGQPPLSATVTLTVAVADRIPDILADLGSLEPSA-------------KPNDS------ 687
Query: 712 LDLTLILIIALGSVSFIFLLAMIVLAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCC 771
DLTL L++A+ +VS +FL +IVL
Sbjct: 688 -DLTLYLVVAVAAVSCVFLAFVIVLLA--------------------------------- 713
Query: 772 GRQARARKKKLSKSDIMLVQSSNVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAK 831
R ++ KS ++ + S P + G G Q Y ++V LT +S K
Sbjct: 714 -----LRLQRWHKSRLLQASGGGLASMPGSHFV---GVEGVRAFLQTYSHEVSLTADSRK 765
Query: 832 TDLMFLKPCSPSRSTDTEHNPCGAIVTGYTDQQPDIISNGSILSNETKHQRAEL------ 885
+ L+F +P DT N Y +P +I+ + ETK + +L
Sbjct: 766 SHLIFPQP----NYADTLINQ-----ESYEKSEPLLITQDLL---ETKGEPRQLQQAPPN 813
Query: 886 -SYLVDRPRRVNSSAFQEADIVSSKDSGHGDSEQGDSD--HDATNRAQSAGMDLFSNCTE 942
+ + +R +S Q D D+G + Q D++ + S D S
Sbjct: 814 TDWRFSQAQRPGTSGSQNGD-----DTGTWPNNQFDTEMLQAMILASASEAADGSSTLGG 868
Query: 943 ECKALGHSDRCWMPSFVPSDGRQAADYRSNLHVPGMDS 980
+G S R + P F + DYR N+++PG ++
Sbjct: 869 GAGTMGLSAR-YGPQFTL---QHVPDYRQNVYIPGSNA 902
>gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo
sapiens]
Length = 814
Score = 602 bits (1551), Expect = e-172
Identities = 341/844 (40%), Positives = 487/844 (57%), Gaps = 82/844 (9%)
Query: 1 MIVLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSR 60
+++LLL W V QLHY+V EE +HGTFVG IA+DLGL++ +L R F+
Sbjct: 14 LLLLLLLLAAWKVGS--GQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRH 71
Query: 61 TPYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPP 120
L+++L+ G+L+VN +IDRE++C +S C +HLEV ++ PL++F V++EV D+NDNPP
Sbjct: 72 RDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVNDNPP 131
Query: 121 SFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRF 180
F D + +SES P +RFPLE A D DVG NS+ Y ++ + YF LDV ++ D N+
Sbjct: 132 VFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDENKL 191
Query: 181 AELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRV 240
ELVL K LDRE H LTA DGG + + TGT L + V
Sbjct: 192 VELVLRKSLDREDAPAHHLFLTATDGG-------------------KPELTGTVQLLVTV 232
Query: 241 LDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRAREL 300
LD NDN P F+Q Y V + EN+ GT VI+LNA+DPDEG NG + YSF+S + +
Sbjct: 233 LDVNDNAPTFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDH 292
Query: 301 FGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISF 360
F + TG + + G LD+E+ +Y++ + A D G + HC VLVR+LD NDN PEI+
Sbjct: 293 FSIDRNTGEIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIAL 352
Query: 361 STVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAP 420
+++ V E A GTV+AL SV D DS NGQV C L+ VPF+L S+FKNYY++V ++
Sbjct: 353 TSLSLPVREDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSA 412
Query: 421 LDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGA 480
LDRE +Y L V ARD G P+L + S+ V+V+DVNDNAP F+QP Y V+V ENN PG
Sbjct: 413 LDRERVSAYELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGC 472
Query: 481 YIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFS 540
+I+ VSA D D NA ++YS++E ++ S+ +Y+S+++E+G +YAL+ D+E+L+
Sbjct: 473 HIFTVSARDADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQ 532
Query: 541 FQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLL 600
FQV ARDAG P L N T+ + ++D+NDNAPA++ P G G A +++PRS G+++
Sbjct: 533 FQVSARDAGVP-PLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVV 591
Query: 601 TRVAAVDADDGENARLTYSI--VRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVI 658
+V AVDAD G NA L+Y + + FR+ TGE+ T R + P+ + L++
Sbjct: 592 AKVRAVDADSGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPR--HRLLV 649
Query: 659 EVRDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLIL 718
V+DHG+P L++TAT++V LV+ P+ G G +D+ + L
Sbjct: 650 LVKDHGEPALTATATVLVSLVESGQAPKASSRQSAGVLGPE---------AALVDVNVYL 700
Query: 719 IIALGSVSFIFLLAMIVLAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARAR 778
IIA+ +VS + +L ++ +YT L C GG RA
Sbjct: 701 IIAICAVSSLLVLTLL-------------LYTALR-----CSALPTEGG-------CRAG 735
Query: 779 KKKLSKSDIMLVQSSNVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKTDLMFLK 838
K LV SS V GS ++Q +VC KTDLM
Sbjct: 736 KP-------TLVCSSAV---------------GSWSYSQQQPQRVCSGEGPPKTDLMAFS 773
Query: 839 PCSP 842
PC P
Sbjct: 774 PCLP 777
>gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens]
Length = 950
Score = 602 bits (1551), Expect = e-172
Identities = 341/844 (40%), Positives = 487/844 (57%), Gaps = 82/844 (9%)
Query: 1 MIVLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSR 60
+++LLL W V QLHY+V EE +HGTFVG IA+DLGL++ +L R F+
Sbjct: 14 LLLLLLLLAAWKVGS--GQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRH 71
Query: 61 TPYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPP 120
L+++L+ G+L+VN +IDRE++C +S C +HLEV ++ PL++F V++EV D+NDNPP
Sbjct: 72 RDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVNDNPP 131
Query: 121 SFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRF 180
F D + +SES P +RFPLE A D DVG NS+ Y ++ + YF LDV ++ D N+
Sbjct: 132 VFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDENKL 191
Query: 181 AELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRV 240
ELVL K LDRE H LTA DGG + + TGT L + V
Sbjct: 192 VELVLRKSLDREDAPAHHLFLTATDGG-------------------KPELTGTVQLLVTV 232
Query: 241 LDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRAREL 300
LD NDN P F+Q Y V + EN+ GT VI+LNA+DPDEG NG + YSF+S + +
Sbjct: 233 LDVNDNAPTFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDH 292
Query: 301 FGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISF 360
F + TG + + G LD+E+ +Y++ + A D G + HC VLVR+LD NDN PEI+
Sbjct: 293 FSIDRNTGEIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIAL 352
Query: 361 STVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAP 420
+++ V E A GTV+AL SV D DS NGQV C L+ VPF+L S+FKNYY++V ++
Sbjct: 353 TSLSLPVREDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSA 412
Query: 421 LDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGA 480
LDRE +Y L V ARD G P+L + S+ V+V+DVNDNAP F+QP Y V+V ENN PG
Sbjct: 413 LDRERVSAYELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGC 472
Query: 481 YIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFS 540
+I+ VSA D D NA ++YS++E ++ S+ +Y+S+++E+G +YAL+ D+E+L+
Sbjct: 473 HIFTVSARDADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQ 532
Query: 541 FQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLL 600
FQV ARDAG P L N T+ + ++D+NDNAPA++ P G G A +++PRS G+++
Sbjct: 533 FQVSARDAGVP-PLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVV 591
Query: 601 TRVAAVDADDGENARLTYSI--VRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVI 658
+V AVDAD G NA L+Y + + FR+ TGE+ T R + P+ + L++
Sbjct: 592 AKVRAVDADSGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPR--HRLLV 649
Query: 659 EVRDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLIL 718
V+DHG+P L++TAT++V LV+ P+ G G +D+ + L
Sbjct: 650 LVKDHGEPALTATATVLVSLVESGQAPKASSRQSAGVLGPE---------AALVDVNVYL 700
Query: 719 IIALGSVSFIFLLAMIVLAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARAR 778
IIA+ +VS + +L ++ +YT L C GG RA
Sbjct: 701 IIAICAVSSLLVLTLL-------------LYTALR-----CSALPTEGG-------CRAG 735
Query: 779 KKKLSKSDIMLVQSSNVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKTDLMFLK 838
K LV SS V GS ++Q +VC KTDLM
Sbjct: 736 KP-------TLVCSSAV---------------GSWSYSQQQPQRVCSGEGPPKTDLMAFS 773
Query: 839 PCSP 842
PC P
Sbjct: 774 PCLP 777
>gi|14196468 protocadherin gamma subfamily A, 4 isoform 2 precursor
[Homo sapiens]
Length = 820
Score = 601 bits (1550), Expect = e-171
Identities = 344/828 (41%), Positives = 488/828 (58%), Gaps = 77/828 (9%)
Query: 12 MVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRTPYLDLNLETG 71
+VE Q+ Y+V EEQE G+ VGNIA+DLGL +L+ RG + V RT LN +G
Sbjct: 23 LVEIRAEQILYSVFEEQEEGSVVGNIAKDLGLAPRELAERGVRIVSRGRTQLFALNPRSG 82
Query: 72 VLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPSFPEPDLTVEI 131
L +IDRE++C +SP+CV +LE+ LE+ +++ +VE+E++D+NDNPPSF +++
Sbjct: 83 TLVTAGRIDREELCDRSPNCVTNLEILLEDTVKILRVEVEIIDVNDNPPSFGTEQREIKV 142
Query: 132 SESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAELVLEKPLDR 191
+E+ PG RFPL AFDPDVG NSL+ Y++ N YFSLDVQ+ DG ++ ELVLE+ LDR
Sbjct: 143 AENENPGARFPLPEAFDPDVGVNSLQGYQLNSNGYFSLDVQSGADGIKYPELVLERALDR 202
Query: 192 EQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLDSNDNVPAFD 251
E++AVH VLTA DGG R+GTA + I ++D+NDN P F
Sbjct: 203 EEEAVHHLVLTAFDGG-------------------DPVRSGTARILIILVDTNDNAPVFT 243
Query: 252 QPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGLSPRTGRLE 311
QP Y VS+ EN P GT ++ + ATDPDEG NG+V YSF + + +LF L+ +G +
Sbjct: 244 QPEYHVSVRENVPVGTRLLTVKATDPDEGANGDVTYSFRK-VRDKISQLFQLNSLSGDIT 302
Query: 312 VSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFSTVKEAVSEGA 371
+ G LDYE+S Y + V+A D GP + A KVLV VLD NDNAPE++ +++ +V E +
Sbjct: 303 ILGGLDYEDSGFYDIDVEAHD-GP-GLRARSKVLVTVLDENDNAPEVTVTSLTSSVQESS 360
Query: 372 APGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLDREAGDSYTL 431
+PGTV+ALF+V D DS NG V C + ++PF L+ ++ NYY ++T LDRE Y +
Sbjct: 361 SPGTVIALFNVHDSDSGGNGLVTCSIPDNLPFTLEKTYGNYYRLLTHRTLDREEVSEYNI 420
Query: 432 TVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRD 491
TV A D+G P LST I +QV D+NDN P F Y Y+ ENN GA I +++A D D
Sbjct: 421 TVTATDQGTPPLSTETHISLQVMDINDNPPTFPHASYSAYIPENNPRGASILSMTAQDPD 480
Query: 492 EGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQVEARDAGSP 551
G NA++ YS+ E QG + +YVSINS G LYAL SFDYEQ +D + A D+G P
Sbjct: 481 SGDNARITYSLAEDTFQGAPLSSYVSINSNTGILYALCSFDYEQFRDLQLLMTASDSGDP 540
Query: 552 QALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTRVAAVDADDG 611
L+ N ++++ ++DQNDN P I+ P +G+ E+ PRSA+ GYL+T+V AVD D G
Sbjct: 541 -PLSSNVSLSLFVLDQNDNVPEILYPTFPTDGSTGVELAPRSADSGYLVTKVVAVDRDSG 599
Query: 612 ENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSST 671
+NA L+YS+++ +E LF + TGE+RTAR + RD + LV+ V+DHGQPPLS+T
Sbjct: 600 QNAWLSYSLLKSSEPGLFAVGLHTGEVRTARAL-LDRDALK-QRLVVVVQDHGQPPLSAT 657
Query: 672 ATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILIIALGSVSFIFLL 731
TL V + D + GS + P SG LTL L++A+ +VS +FL
Sbjct: 658 VTLTVAVADSIPDVLADLGSLKPSAD----PDDSG-------LTLYLVVAVAAVSCVFLA 706
Query: 732 AMIVLAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARARKKKLSKSDIMLVQ 791
+ VL + ++ KS ++ +
Sbjct: 707 FVTVLLA--------------------------------------LKLRRWHKSRLLHAE 728
Query: 792 SSNVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKTDLMFLKP 839
S + PA + G G Q Y ++V LT +S K+ L+F +P
Sbjct: 729 GSRLAGVPASHFV---GVDGVRAFLQTYSHEVSLTADSRKSHLIFSQP 773
>gi|11056026 protocadherin gamma subfamily A, 4 isoform 1 precursor
[Homo sapiens]
Length = 931
Score = 601 bits (1550), Expect = e-171
Identities = 344/828 (41%), Positives = 488/828 (58%), Gaps = 77/828 (9%)
Query: 12 MVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRTPYLDLNLETG 71
+VE Q+ Y+V EEQE G+ VGNIA+DLGL +L+ RG + V RT LN +G
Sbjct: 23 LVEIRAEQILYSVFEEQEEGSVVGNIAKDLGLAPRELAERGVRIVSRGRTQLFALNPRSG 82
Query: 72 VLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPSFPEPDLTVEI 131
L +IDRE++C +SP+CV +LE+ LE+ +++ +VE+E++D+NDNPPSF +++
Sbjct: 83 TLVTAGRIDREELCDRSPNCVTNLEILLEDTVKILRVEVEIIDVNDNPPSFGTEQREIKV 142
Query: 132 SESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAELVLEKPLDR 191
+E+ PG RFPL AFDPDVG NSL+ Y++ N YFSLDVQ+ DG ++ ELVLE+ LDR
Sbjct: 143 AENENPGARFPLPEAFDPDVGVNSLQGYQLNSNGYFSLDVQSGADGIKYPELVLERALDR 202
Query: 192 EQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLDSNDNVPAFD 251
E++AVH VLTA DGG R+GTA + I ++D+NDN P F
Sbjct: 203 EEEAVHHLVLTAFDGG-------------------DPVRSGTARILIILVDTNDNAPVFT 243
Query: 252 QPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGLSPRTGRLE 311
QP Y VS+ EN P GT ++ + ATDPDEG NG+V YSF + + +LF L+ +G +
Sbjct: 244 QPEYHVSVRENVPVGTRLLTVKATDPDEGANGDVTYSFRK-VRDKISQLFQLNSLSGDIT 302
Query: 312 VSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFSTVKEAVSEGA 371
+ G LDYE+S Y + V+A D GP + A KVLV VLD NDNAPE++ +++ +V E +
Sbjct: 303 ILGGLDYEDSGFYDIDVEAHD-GP-GLRARSKVLVTVLDENDNAPEVTVTSLTSSVQESS 360
Query: 372 APGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLDREAGDSYTL 431
+PGTV+ALF+V D DS NG V C + ++PF L+ ++ NYY ++T LDRE Y +
Sbjct: 361 SPGTVIALFNVHDSDSGGNGLVTCSIPDNLPFTLEKTYGNYYRLLTHRTLDREEVSEYNI 420
Query: 432 TVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRD 491
TV A D+G P LST I +QV D+NDN P F Y Y+ ENN GA I +++A D D
Sbjct: 421 TVTATDQGTPPLSTETHISLQVMDINDNPPTFPHASYSAYIPENNPRGASILSMTAQDPD 480
Query: 492 EGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQVEARDAGSP 551
G NA++ YS+ E QG + +YVSINS G LYAL SFDYEQ +D + A D+G P
Sbjct: 481 SGDNARITYSLAEDTFQGAPLSSYVSINSNTGILYALCSFDYEQFRDLQLLMTASDSGDP 540
Query: 552 QALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTRVAAVDADDG 611
L+ N ++++ ++DQNDN P I+ P +G+ E+ PRSA+ GYL+T+V AVD D G
Sbjct: 541 -PLSSNVSLSLFVLDQNDNVPEILYPTFPTDGSTGVELAPRSADSGYLVTKVVAVDRDSG 599
Query: 612 ENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSST 671
+NA L+YS+++ +E LF + TGE+RTAR + RD + LV+ V+DHGQPPLS+T
Sbjct: 600 QNAWLSYSLLKSSEPGLFAVGLHTGEVRTARAL-LDRDALK-QRLVVVVQDHGQPPLSAT 657
Query: 672 ATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILIIALGSVSFIFLL 731
TL V + D + GS + P SG LTL L++A+ +VS +FL
Sbjct: 658 VTLTVAVADSIPDVLADLGSLKPSAD----PDDSG-------LTLYLVVAVAAVSCVFLA 706
Query: 732 AMIVLAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARARKKKLSKSDIMLVQ 791
+ VL + ++ KS ++ +
Sbjct: 707 FVTVLLA--------------------------------------LKLRRWHKSRLLHAE 728
Query: 792 SSNVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKTDLMFLKP 839
S + PA + G G Q Y ++V LT +S K+ L+F +P
Sbjct: 729 GSRLAGVPASHFV---GVDGVRAFLQTYSHEVSLTADSRKSHLIFSQP 773
>gi|11056032 protocadherin gamma subfamily A, 1 isoform 1 precursor
[Homo sapiens]
Length = 931
Score = 601 bits (1549), Expect = e-171
Identities = 372/995 (37%), Positives = 545/995 (54%), Gaps = 122/995 (12%)
Query: 2 IVLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRT 61
++LL +L ++E +HY+V EE + G+FVGNIA+DLGL +L+ G + V R
Sbjct: 13 LMLLCLSLELLLEAGAGNIHYSVPEETDKGSFVGNIAKDLGLQPQELADGGVRIVSRGRM 72
Query: 62 PYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPS 121
P LN +G L +IDRE++C QS C++ + +E+ ++LF VE+E++DINDN P
Sbjct: 73 PLFALNPRSGSLITARRIDREELCAQSMPCLVSFNILVEDKMKLFPVEVEIIDINDNTPQ 132
Query: 122 FPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFA 181
F +L +++E TPGTR L D DVG NSL+ Y+++ N +FSLDVQ DG +
Sbjct: 133 FQLEELEFKMNEITTPGTRVSLPFGQDLDVGMNSLQSYQLSSNPHFSLDVQQGADGPQHP 192
Query: 182 ELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVL 241
E+VL+ PLDRE++AVH +LTA DGG + R+GT + I+V+
Sbjct: 193 EMVLQSPLDREEEAVHHLILTASDGG-------------------EPVRSGTLRIYIQVV 233
Query: 242 DSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELF 301
D+NDN PAF Q Y +++PEN P GT ++ +NATDPDEG NGEV YSF + + R ++F
Sbjct: 234 DANDNPPAFTQAQYHINVPENVPLGTQLLMVNATDPDEGANGEVTYSFHN-VDHRVAQIF 292
Query: 302 GLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFS 361
L TG + LD+EE +Y + VQA+D + A KVL++VLD NDNAPE++ +
Sbjct: 293 RLDSYTGEISNKEPLDFEEYKMYSMEVQAQDGA--GLMAKVKVLIKVLDVNDNAPEVTIT 350
Query: 362 TVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPL 421
+V AV E PGT++AL SV D+DS +NG C + G++PF+L+ NYY +VTE L
Sbjct: 351 SVTTAVPENFPPGTIIALISVHDQDSGDNGYTTCFIPGNLPFKLEKLVDNYYRLVTERTL 410
Query: 422 DREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAY 481
DRE Y +T+ A D+G PALST I + V+D+NDN+P F Q Y Y+ ENN GA
Sbjct: 411 DRELISGYNITITAIDQGTPALSTETHISLLVTDINDNSPVFHQDSYSAYIPENNPRGAS 470
Query: 482 IYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSF 541
I++V A D D NAQ+ YS++E IQG + Y+SINS+ G LYALRSFDYEQ +D
Sbjct: 471 IFSVRAHDLDSNENAQITYSLIEDTIQGAPLSAYLSINSDTGVLYALRSFDYEQFRDMQL 530
Query: 542 QVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLT 601
+V ARD+G P L+ N ++++ ++DQNDNAP I+ P +G+ E+ P SAEPGYL+T
Sbjct: 531 KVMARDSGDP-PLSSNVSLSLFLLDQNDNAPEILYPALPTDGSTGVELAPLSAEPGYLVT 589
Query: 602 RVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVR 661
+V AVD D G+NA L+Y +++ +E LF + TGE+RTAR + RD + LV+ V+
Sbjct: 590 KVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARAL-LDRDALK-QSLVVAVQ 647
Query: 662 DHGQPPLSSTATLVVQLVD---------GAVEPQGGGGSGGGGSGEHQRPSRSGGGETSL 712
DHGQPPLS+T TL V + D G++EP +P+ S
Sbjct: 648 DHGQPPLSATVTLTVAVADRISDILADLGSLEPSA-------------KPNDS------- 687
Query: 713 DLTLILIIALGSVSFIFLLAMIVLAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCG 772
DLTL L++A +VS +FL +IVL
Sbjct: 688 DLTLYLVVAAAAVSCVFLAFVIVLLAH--------------------------------- 714
Query: 773 RQARARKKKLSKSDIMLVQSSNVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKT 832
R ++ KS ++ + S P + G G Q Y ++V LT +S K+
Sbjct: 715 -----RLRRWHKSRLLQASGGGLASMPGSHFV---GVDGVRAFLQTYSHEVSLTADSRKS 766
Query: 833 DLMFLKPCSPSRSTDTEHNPCGAIVTGYTDQQPDIISNGSILSNETKH---QRA--ELSY 887
L+F +P N +++ + ++ +S L + K Q+A +
Sbjct: 767 HLIFPQP-----------NYADTLISQESCEKKGFLSAPQSLLEDKKEPFSQQAPPNTDW 815
Query: 888 LVDRPRRVNSSAFQEADIVSSKDSGHGDSEQGDSD--HDATNRAQSAGMDLFSNCTEECK 945
+ +R +S Q D D+G + Q D++ + S D S
Sbjct: 816 RFSQAQRPGTSGSQNGD-----DTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAG 870
Query: 946 ALGHSDRCWMPSFVPSDGRQAADYRSNLHVPGMDS 980
+G S R + P F + DYR N+++PG ++
Sbjct: 871 TMGLSAR-YGPQFTL---QHVPDYRQNVYIPGSNA 901
>gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo
sapiens]
Length = 798
Score = 599 bits (1545), Expect = e-171
Identities = 322/741 (43%), Positives = 466/741 (62%), Gaps = 34/741 (4%)
Query: 3 VLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRTP 62
+LLL LL E QLHY+V EE +HGTFVG IA+DLGL++ +L R F+ R
Sbjct: 14 LLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGG 73
Query: 63 YLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPSF 122
L++NL+ G+L+VN +IDRE++C++S C +HLEV ++ PL++F V++EV DINDNPP F
Sbjct: 74 LLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPVF 133
Query: 123 PEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAE 182
P + I+ES +RFPLE A D D+G N+L Y ++PN YFSL+ + +
Sbjct: 134 PATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDELVKGLG 193
Query: 183 LVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLD 242
L+L K LDRE+ VLTA DGG + + TGT L I VLD
Sbjct: 194 LILRKSLDREEAPEIFLVLTATDGG-------------------KPELTGTVQLLITVLD 234
Query: 243 SNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFG 302
+NDN PAFD+ +Y V L EN P GTLVI+LNA+D DEG NG++VYSFS+ ISP + F
Sbjct: 235 ANDNAPAFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFH 294
Query: 303 LSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFST 362
+ P TG++ V G +D+EES Y++ V+ D G + HC+V+V V D NDN P++ F +
Sbjct: 295 IDPITGQIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKS 354
Query: 363 VKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLD 422
+ + E A GTV+AL SV+D+D NG V C L VPF+L S+FKNYY++V ++ LD
Sbjct: 355 LSLPIREDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALD 414
Query: 423 REAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYI 482
RE+ +Y L V ARD G P+L + S+ V+V+DVNDNAP F+QP Y V+V ENN PG +I
Sbjct: 415 RESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHI 474
Query: 483 YAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQ 542
+ VSA D D NA ++YS++E ++ ++ +YVS+++E+G +YAL+ D+E+L+ FQ
Sbjct: 475 FTVSAWDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQ 534
Query: 543 VEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTR 602
V ARDAG P L N T+ + ++D+NDNAPA++AP G G E++P S G+++ +
Sbjct: 535 VTARDAGVP-PLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAK 593
Query: 603 VAAVDADDGENARLTYSIV--RGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEV 660
V AVDAD G NA L+Y + G FR+ TGE+ T R + P+ + L++ V
Sbjct: 594 VRAVDADSGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPR--HRLLVLV 651
Query: 661 RDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILII 720
+DHG+P L++TAT++V LV+ P+ + G G +D+ + LII
Sbjct: 652 KDHGEPALTATATVLVSLVESGQAPKASSRALVGAVGP---------DAALVDVNVYLII 702
Query: 721 ALGSVSFIFLLAMIV-LAVRC 740
A+ +VS + +L +++ A+RC
Sbjct: 703 AICAVSSLLVLTLLLYTALRC 723
>gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens]
Length = 947
Score = 599 bits (1545), Expect = e-171
Identities = 322/741 (43%), Positives = 466/741 (62%), Gaps = 34/741 (4%)
Query: 3 VLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRTP 62
+LLL LL E QLHY+V EE +HGTFVG IA+DLGL++ +L R F+ R
Sbjct: 14 LLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGG 73
Query: 63 YLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPSF 122
L++NL+ G+L+VN +IDRE++C++S C +HLEV ++ PL++F V++EV DINDNPP F
Sbjct: 74 LLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPVF 133
Query: 123 PEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAE 182
P + I+ES +RFPLE A D D+G N+L Y ++PN YFSL+ + +
Sbjct: 134 PATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDELVKGLG 193
Query: 183 LVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLD 242
L+L K LDRE+ VLTA DGG + + TGT L I VLD
Sbjct: 194 LILRKSLDREEAPEIFLVLTATDGG-------------------KPELTGTVQLLITVLD 234
Query: 243 SNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFG 302
+NDN PAFD+ +Y V L EN P GTLVI+LNA+D DEG NG++VYSFS+ ISP + F
Sbjct: 235 ANDNAPAFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFH 294
Query: 303 LSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFST 362
+ P TG++ V G +D+EES Y++ V+ D G + HC+V+V V D NDN P++ F +
Sbjct: 295 IDPITGQIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKS 354
Query: 363 VKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLD 422
+ + E A GTV+AL SV+D+D NG V C L VPF+L S+FKNYY++V ++ LD
Sbjct: 355 LSLPIREDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALD 414
Query: 423 REAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYI 482
RE+ +Y L V ARD G P+L + S+ V+V+DVNDNAP F+QP Y V+V ENN PG +I
Sbjct: 415 RESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHI 474
Query: 483 YAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQ 542
+ VSA D D NA ++YS++E ++ ++ +YVS+++E+G +YAL+ D+E+L+ FQ
Sbjct: 475 FTVSAWDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQ 534
Query: 543 VEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTR 602
V ARDAG P L N T+ + ++D+NDNAPA++AP G G E++P S G+++ +
Sbjct: 535 VTARDAGVP-PLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAK 593
Query: 603 VAAVDADDGENARLTYSIV--RGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEV 660
V AVDAD G NA L+Y + G FR+ TGE+ T R + P+ + L++ V
Sbjct: 594 VRAVDADSGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPR--HRLLVLV 651
Query: 661 RDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILII 720
+DHG+P L++TAT++V LV+ P+ + G G +D+ + LII
Sbjct: 652 KDHGEPALTATATVLVSLVESGQAPKASSRALVGAVGP---------DAALVDVNVYLII 702
Query: 721 ALGSVSFIFLLAMIV-LAVRC 740
A+ +VS + +L +++ A+RC
Sbjct: 703 AICAVSSLLVLTLLLYTALRC 723
>gi|14196474 protocadherin gamma subfamily A, 6 isoform 2 precursor
[Homo sapiens]
Length = 818
Score = 599 bits (1544), Expect = e-171
Identities = 336/755 (44%), Positives = 467/755 (61%), Gaps = 57/755 (7%)
Query: 1 MIVLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSR 60
+++L L LW +Q+ Y++ EE E G+FVGNI +DLGL+ +L+ G + V R
Sbjct: 14 VLLLTLLGTLWGAAA--AQIRYSIPEELEKGSFVGNIVKDLGLEPQELAEHGVRIVSRGR 71
Query: 61 TPYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPP 120
LN G L +IDRE++C QSP C++ + +E+ L L+ VE+E++DINDN P
Sbjct: 72 MQLFSLNPRNGSLVTAGRIDREELCAQSPRCLVSFNILVEDKLNLYPVEVEIVDINDNTP 131
Query: 121 SFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRF 180
F + +L V+I E+A P +RFPL +DPDVG NSL+ ++++ NS+FS+DVQ++ G ++
Sbjct: 132 RFLKEELEVKILENAAPSSRFPLMEVYDPDVGMNSLQGFKLSGNSHFSVDVQSEAHGPKY 191
Query: 181 AELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRV 240
ELVLE LDRE +AV+R VLTA+DGG R+ A + + V
Sbjct: 192 PELVLEGTLDREGEAVYRLVLTAMDGG-------------------DPVRSSVAQILVTV 232
Query: 241 LDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRAREL 300
LD NDN P F QPVY VS+PEN P GT V+ + ATD DEG +GEV YSF I+ + ++
Sbjct: 233 LDVNDNTPMFTQPVYRVSVPENLPVGTPVLAVTATDQDEGVHGEVTYSFVK-ITEKISQI 291
Query: 301 FGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISF 360
F L+ TG + S LDYE+S Y++ V+A+D GP + KVL+ +LD NDN PE+
Sbjct: 292 FCLNVLTGEISTSANLDYEDSSFYELGVEARD-GPG-LRDRAKVLITILDVNDNVPEVVV 349
Query: 361 STVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAP 420
++ ++E A PGTV+ALF V DRDS NG V C + +PF L+ S NYY +VT A
Sbjct: 350 TSGSRTIAESAPPGTVIALFQVFDRDSGLNGLVTCSIPRSLPFELEKSVGNYYRLVTNAA 409
Query: 421 LDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGA 480
LDRE Y +TV A D+G P LST I + V+D NDN P F Y VYV ENN GA
Sbjct: 410 LDREEVFLYNITVTATDKGTPPLSTETIISLNVADTNDNPPTFPHSSYSVYVLENNPRGA 469
Query: 481 YIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFS 540
I++V+A D D NAQ++YS+ E +QG + +YVSINS+ G LYALRSFDYEQL+D
Sbjct: 470 SIFSVNALDPDVDQNAQVSYSLAEDTLQGAPLSSYVSINSDTGILYALRSFDYEQLRDLQ 529
Query: 541 FQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLL 600
V A D+G P L+ N ++++ ++DQNDNAP I+ P +G+ E+ PRSAEPGYL+
Sbjct: 530 LWVTASDSGDP-PLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLV 588
Query: 601 TRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEV 660
T+V AVD D G+NA L+Y +++ +E LF + TGE+RTAR + RD + LV+ V
Sbjct: 589 TKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARAL-LDRDALK-QSLVVAV 646
Query: 661 RDHGQPPLSSTATLVVQLVD---------GAVEPQGGGGSGGGGSGEHQRPSRSGGGETS 711
+DHGQPPLS+T TL V + D G++EP +P+ S
Sbjct: 647 QDHGQPPLSATVTLTVAVADRIPDILADLGSLEPSA-------------KPNDS------ 687
Query: 712 LDLTLILIIALGSVSFIFLLAMIV-LAVRCQKEKK 745
DLTL L++A+ +VS +FL +IV LA+R Q+ K
Sbjct: 688 -DLTLYLVVAVAAVSCVFLAFVIVLLALRLQRWHK 721
>gi|14196459 protocadherin gamma subfamily A, 1 isoform 2 precursor
[Homo sapiens]
Length = 823
Score = 598 bits (1542), Expect = e-171
Identities = 344/847 (40%), Positives = 491/847 (57%), Gaps = 95/847 (11%)
Query: 2 IVLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRT 61
++LL +L ++E +HY+V EE + G+FVGNIA+DLGL +L+ G + V R
Sbjct: 13 LMLLCLSLELLLEAGAGNIHYSVPEETDKGSFVGNIAKDLGLQPQELADGGVRIVSRGRM 72
Query: 62 PYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPS 121
P LN +G L +IDRE++C QS C++ + +E+ ++LF VE+E++DINDN P
Sbjct: 73 PLFALNPRSGSLITARRIDREELCAQSMPCLVSFNILVEDKMKLFPVEVEIIDINDNTPQ 132
Query: 122 FPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFA 181
F +L +++E TPGTR L D DVG NSL+ Y+++ N +FSLDVQ DG +
Sbjct: 133 FQLEELEFKMNEITTPGTRVSLPFGQDLDVGMNSLQSYQLSSNPHFSLDVQQGADGPQHP 192
Query: 182 ELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVL 241
E+VL+ PLDRE++AVH +LTA DGG + R+GT + I+V+
Sbjct: 193 EMVLQSPLDREEEAVHHLILTASDGG-------------------EPVRSGTLRIYIQVV 233
Query: 242 DSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELF 301
D+NDN PAF Q Y +++PEN P GT ++ +NATDPDEG NGEV YSF + + R ++F
Sbjct: 234 DANDNPPAFTQAQYHINVPENVPLGTQLLMVNATDPDEGANGEVTYSFHN-VDHRVAQIF 292
Query: 302 GLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFS 361
L TG + LD+EE +Y + VQA+D + A KVL++VLD NDNAPE++ +
Sbjct: 293 RLDSYTGEISNKEPLDFEEYKMYSMEVQAQDGA--GLMAKVKVLIKVLDVNDNAPEVTIT 350
Query: 362 TVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPL 421
+V AV E PGT++AL SV D+DS +NG C + G++PF+L+ NYY +VTE L
Sbjct: 351 SVTTAVPENFPPGTIIALISVHDQDSGDNGYTTCFIPGNLPFKLEKLVDNYYRLVTERTL 410
Query: 422 DREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAY 481
DRE Y +T+ A D+G PALST I + V+D+NDN+P F Q Y Y+ ENN GA
Sbjct: 411 DRELISGYNITITAIDQGTPALSTETHISLLVTDINDNSPVFHQDSYSAYIPENNPRGAS 470
Query: 482 IYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSF 541
I++V A D D NAQ+ YS++E IQG + Y+SINS+ G LYALRSFDYEQ +D
Sbjct: 471 IFSVRAHDLDSNENAQITYSLIEDTIQGAPLSAYLSINSDTGVLYALRSFDYEQFRDMQL 530
Query: 542 QVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLT 601
+V ARD+G P L+ N ++++ ++DQNDNAP I+ P +G+ E+ P SAEPGYL+T
Sbjct: 531 KVMARDSGDP-PLSSNVSLSLFLLDQNDNAPEILYPALPTDGSTGVELAPLSAEPGYLVT 589
Query: 602 RVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVR 661
+V AVD D G+NA L+Y +++ +E LF + TGE+RTAR + RD + LV+ V+
Sbjct: 590 KVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARAL-LDRDALK-QSLVVAVQ 647
Query: 662 DHGQPPLSSTATLVVQLVD---------GAVEPQGGGGSGGGGSGEHQRPSRSGGGETSL 712
DHGQPPLS+T TL V + D G++EP +P+ S
Sbjct: 648 DHGQPPLSATVTLTVAVADRISDILADLGSLEPSA-------------KPNDS------- 687
Query: 713 DLTLILIIALGSVSFIFLLAMIVLAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCG 772
DLTL L++A +VS +FL +IVL
Sbjct: 688 DLTLYLVVAAAAVSCVFLAFVIVLLAH--------------------------------- 714
Query: 773 RQARARKKKLSKSDIMLVQSSNVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKT 832
R ++ KS ++ + S P + G G Q Y ++V LT +S K+
Sbjct: 715 -----RLRRWHKSRLLQASGGGLASMPGSHFV---GVDGVRAFLQTYSHEVSLTADSRKS 766
Query: 833 DLMFLKP 839
L+F +P
Sbjct: 767 HLIFPQP 773
>gi|11056030 protocadherin gamma subfamily A, 2 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 598 bits (1542), Expect = e-171
Identities = 367/987 (37%), Positives = 543/987 (55%), Gaps = 105/987 (10%)
Query: 2 IVLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRT 61
+VLL F L + E Q+ Y+V+EE + G+FVGNIA+DLGL+ L+ +G + V R+
Sbjct: 13 LVLLCFLLATLWEARAGQIRYSVREEIDRGSFVGNIAKDLGLEPLALAEQGVRIVSRGRS 72
Query: 62 PYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPS 121
LN +G L +IDRE++C QS C+L+ + LE+ L ++ VE+E+ DINDN P
Sbjct: 73 QLFALNPRSGSLVTANRIDREELCAQSAPCLLNFNILLEDKLTIYSVEVEITDINDNAPR 132
Query: 122 FPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFA 181
F +L ++ISE+ TPG R PL++A D DVG N+L+ Y + PN +FSLDV+ DGN++
Sbjct: 133 FGVEELELKISETTTPGFRIPLKNAHDADVGENALQKYALNPNDHFSLDVRRGADGNKYP 192
Query: 182 ELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVL 241
ELVLE+ LDRE++AVH VL A DGG +GT+ + ++VL
Sbjct: 193 ELVLERSLDREEEAVHHLVLVASDGG-------------------DPVLSGTSRICVKVL 233
Query: 242 DSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELF 301
D+NDN P F QP Y +S+PEN+ GT ++ + ATD DEG +VVY F E+F
Sbjct: 234 DANDNAPVFTQPEYRISIPENTLVGTRILTVTATDADEGYYAQVVY-FLEKSPGETSEVF 292
Query: 302 GLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFS 361
L +G L + +LDYE++ +++ ++A+D GP + KV+V VLD NDNAPE +
Sbjct: 293 ELKSTSGELTIIKDLDYEDATFHEIDIEAQD-GPGLL-TRAKVIVTVLDVNDNAPEFYMT 350
Query: 362 TVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPL 421
+ +VSE + PGT++ LF+V DRDS +N C L D+PF+L+ S NYY +VT L
Sbjct: 351 SATSSVSEDSLPGTIIGLFNVHDRDSGQNAFTTCSLPEDLPFKLEKSVDNYYRLVTTRAL 410
Query: 422 DREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAY 481
DRE Y +T+ A+D G P+LST I +QV+D+NDNAP FS+ Y Y+ ENN GA
Sbjct: 411 DREQFSFYNITLTAKDGGNPSLSTDAHILLQVADINDNAPAFSRTSYSTYIPENNPRGAS 470
Query: 482 IYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSF 541
+++V+A D D NA + YS E +QG + +Y+SINS+ G LYALRSFDYEQL+D
Sbjct: 471 VFSVTAHDPDSNDNAHVTYSFAEDTVQGAPLSSYISINSDTGVLYALRSFDYEQLRDLQV 530
Query: 542 QVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLT 601
V ARD+G+P L+ N ++++ ++DQNDNAP I+ P +G+ E+ PRSAEPGYL+T
Sbjct: 531 WVIARDSGNP-PLSSNVSLSLFVLDQNDNAPEILYPAFPTDGSTGVELAPRSAEPGYLVT 589
Query: 602 RVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVR 661
+V AVD D G+NA L+Y +++ +E LF + TGE+RTAR + RD + LV+ ++
Sbjct: 590 KVVAVDRDSGQNAWLSYHLLKASEPGLFSVGLHTGEVRTARAL-LDRDALK-QSLVVAIQ 647
Query: 662 DHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILIIA 721
DHGQPPLS+T TL V + D + GS PS DLTL L++A
Sbjct: 648 DHGQPPLSATVTLTVAVADRIPDILADLGS--------LEPSAI---PNDSDLTLYLVVA 696
Query: 722 LGSVSFIFLLAMIVLAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARARKKK 781
+ +VS +FL +IVL + R ++R +
Sbjct: 697 VAAVSCVFLAFVIVLLAHRLR------------------------------RWHKSRLLQ 726
Query: 782 LSKSDIMLVQSSNVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKTDLMFLKPCS 841
S + +QSS+ G G Q Y ++V LT +S K+ L+F +P
Sbjct: 727 ASGGSLTGMQSSHF-----------VGVDGVRAFLQTYSHEVSLTADSRKSHLIFPQP-- 773
Query: 842 PSRSTDTEHNPCGAIVTGYTDQQPDIISNGSILSNETKHQR------AELSYLVDRPRRV 895
N +++ + ++ D +S L E + + + + +R
Sbjct: 774 ---------NYADTLISQESCEKKDFLSAPQSLLEEEREETFSQQAPPNTDWRFSQAQRP 824
Query: 896 NSSAFQEADIVSSKDSGHGDSEQGDSD--HDATNRAQSAGMDLFSNCTEECKALGHSDRC 953
+S Q D D+G + Q D++ + S D S +G S R
Sbjct: 825 GTSGSQNGD-----DTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSAR- 878
Query: 954 WMPSFVPSDGRQAADYRSNLHVPGMDS 980
+ P F + DYR N+++PG ++
Sbjct: 879 YGPQFTL---QHVPDYRQNVYIPGSNA 902
>gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo
sapiens]
Length = 807
Score = 597 bits (1539), Expect = e-170
Identities = 328/797 (41%), Positives = 474/797 (59%), Gaps = 42/797 (5%)
Query: 9 LLWMV-----EGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRTPY 63
LLW++ E QLHY+V EE +HGTFVG IA+DLGL++ +L R F+
Sbjct: 15 LLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRHGDL 74
Query: 64 LDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPSFP 123
L++NL+ G+L+VN +IDRE++C +S C +HLEV ++ PL++F VE++V DINDNPP FP
Sbjct: 75 LEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDINDNPPIFP 134
Query: 124 EPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAEL 183
E + I+ES P TRFPL+ A D D+G NS Y + PN YF+LD Q + L
Sbjct: 135 ESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSLEQMSSLSL 194
Query: 184 VLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLDS 243
VL K LDRE+ H +LTA DGG + + TGT L I +LD
Sbjct: 195 VLRKTLDREEIQEHSLLLTASDGG-------------------KPELTGTVQLLITILDV 235
Query: 244 NDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGL 303
NDN P F Q VY V++ EN+ GTLVI+LNATDPD+G NG++VYSF + P F +
Sbjct: 236 NDNAPEFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTI 295
Query: 304 SPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFSTV 363
+P G + G+LD+EE +Y++ V+A D G + HC +LV VLD NDNAPE++ +++
Sbjct: 296 NPNNGEIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSL 355
Query: 364 KEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLDR 423
+ E P ++AL SV+DRDS NGQV C L VPF+L S++KNYY++V ++ LDR
Sbjct: 356 SLPIREDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDR 415
Query: 424 EAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIY 483
E+ +Y L V ARD G P+L + S+ V V+DVNDNAP F+QP Y V+V ENN PG +I+
Sbjct: 416 ESVSAYELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIF 475
Query: 484 AVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQV 543
VSA D D NA ++YS++E ++ ++ +YVS+++E+G +YAL+ D+E+L+ FQV
Sbjct: 476 TVSAQDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQV 535
Query: 544 EARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTRV 603
ARD+G P L N T+ + ++D+NDNAPA++ P G G E++PRS G+++ +V
Sbjct: 536 SARDSGVP-PLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKV 594
Query: 604 AAVDADDGENARLTY--SIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVR 661
AVDAD G NA L+Y + FR+ TGE+ T R + P + L++ V+
Sbjct: 595 RAVDADSGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPH--HRLLVLVK 652
Query: 662 DHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILIIA 721
DHG+P L++TAT+++ LV+ PQ + G G +D+ + LIIA
Sbjct: 653 DHGEPALTATATVLLSLVESGQAPQASSRASAGAVGPE---------AALVDVNVYLIIA 703
Query: 722 LGSVSFIFLLAMIV-LAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQAR-ARK 779
+ +VS + +L +++ A+RC C L C G S R+ R
Sbjct: 704 ICAVSSLLVLTLLLYTALRCSAPPTEG--ACAPGKPTLVCSSAAGSWSYSQQRRPRVCSG 761
Query: 780 KKLSKSDIMLVQSSNVP 796
+ K+D+M S P
Sbjct: 762 EGPHKTDLMAFSPSLPP 778
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.134 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,243,941
Number of Sequences: 37866
Number of extensions: 2211628
Number of successful extensions: 26203
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 374
Number of HSP's successfully gapped in prelim test: 66
Number of HSP's that attempted gapping in prelim test: 11475
Number of HSP's gapped (non-prelim): 5890
length of query: 1040
length of database: 18,247,518
effective HSP length: 112
effective length of query: 928
effective length of database: 14,006,526
effective search space: 12998056128
effective search space used: 12998056128
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.