Search of human proteins with 14589914

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14589914 protocadherin 10 isoform 2 precursor [Homo sapiens]
         (896 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14589914 protocadherin 10 isoform 2 precursor [Homo sapiens]      1797   0.0  
gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens]      1762   0.0  
gi|94538350 protocadherin 17 precursor [Homo sapiens]                 681   0.0  
gi|157426847 protocadherin 19 isoform a [Homo sapiens]                657   0.0  
gi|157426845 protocadherin 19 isoform b [Homo sapiens]                657   0.0  
gi|14165431 protocadherin alpha subfamily C, 2 isoform 2 precurs...   654   0.0  
gi|9256600 protocadherin alpha subfamily C, 2 isoform 1 precurso...   654   0.0  
gi|14277685 protocadherin gamma subfamily C, 5 isoform 2 precurs...   629   e-180
gi|11128023 protocadherin gamma subfamily C, 5 isoform 1 precurs...   629   e-180
gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens]   613   e-175
gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo sapi...   613   e-175
gi|8850232 protocadherin gamma subfamily A, 12 isoform 1 precurs...   610   e-174
gi|14196457 protocadherin gamma subfamily A, 12 isoform 2 precur...   610   e-174
gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo sapi...   608   e-174
gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens]   608   e-174
gi|11128041 protocadherin gamma subfamily A, 10 isoform 1 precur...   604   e-172
gi|14196448 protocadherin gamma subfamily A, 10 isoform 2 precur...   604   e-172
gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo sapi...   602   e-172
gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens]   602   e-172
gi|14196468 protocadherin gamma subfamily A, 4 isoform 2 precurs...   601   e-172
gi|11056026 protocadherin gamma subfamily A, 4 isoform 1 precurs...   601   e-172
gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo sapi...   599   e-171
gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens]   599   e-171
gi|11056065 protocadherin gamma subfamily A, 6 isoform 1 precurs...   599   e-171
gi|14196474 protocadherin gamma subfamily A, 6 isoform 2 precurs...   599   e-171
gi|11056032 protocadherin gamma subfamily A, 1 isoform 1 precurs...   598   e-171
gi|14196459 protocadherin gamma subfamily A, 1 isoform 2 precurs...   598   e-171
gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo sap...   597   e-170
gi|9256580 protocadherin alpha 13 isoform 1 precursor [Homo sapi...   597   e-170
gi|9256610 protocadherin beta 15 precursor [Homo sapiens]             597   e-170

>gi|14589914 protocadherin 10 isoform 2 precursor [Homo sapiens]
          Length = 896

 Score = 1797 bits (4655), Expect = 0.0
 Identities = 896/896 (100%), Positives = 896/896 (100%)

Query: 1   MIVLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSR 60
           MIVLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSR
Sbjct: 1   MIVLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSR 60

Query: 61  TPYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPP 120
           TPYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPP
Sbjct: 61  TPYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPP 120

Query: 121 SFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRF 180
           SFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRF
Sbjct: 121 SFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRF 180

Query: 181 AELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRV 240
           AELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRV
Sbjct: 181 AELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRV 240

Query: 241 LDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRAREL 300
           LDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRAREL
Sbjct: 241 LDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRAREL 300

Query: 301 FGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISF 360
           FGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISF
Sbjct: 301 FGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISF 360

Query: 361 STVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAP 420
           STVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAP
Sbjct: 361 STVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAP 420

Query: 421 LDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGA 480
           LDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGA
Sbjct: 421 LDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGA 480

Query: 481 YIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFS 540
           YIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFS
Sbjct: 481 YIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFS 540

Query: 541 FQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLL 600
           FQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLL
Sbjct: 541 FQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLL 600

Query: 601 TRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEV 660
           TRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEV
Sbjct: 601 TRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEV 660

Query: 661 RDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILII 720
           RDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILII
Sbjct: 661 RDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILII 720

Query: 721 ALGSVSFIFLLAMIVLAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARARKK 780
           ALGSVSFIFLLAMIVLAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARARKK
Sbjct: 721 ALGSVSFIFLLAMIVLAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARARKK 780

Query: 781 KLSKSDIMLVQSSNVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKTDLMFLKPC 840
           KLSKSDIMLVQSSNVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKTDLMFLKPC
Sbjct: 781 KLSKSDIMLVQSSNVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKTDLMFLKPC 840

Query: 841 SPSRSTDTEHNPCGAIVTGYTDQQPDIISNGSILSNEVRLKRKDHHLSSPPSESLL 896
           SPSRSTDTEHNPCGAIVTGYTDQQPDIISNGSILSNEVRLKRKDHHLSSPPSESLL
Sbjct: 841 SPSRSTDTEHNPCGAIVTGYTDQQPDIISNGSILSNEVRLKRKDHHLSSPPSESLL 896


>gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens]
          Length = 1040

 Score = 1762 bits (4564), Expect = 0.0
 Identities = 878/884 (99%), Positives = 881/884 (99%)

Query: 1   MIVLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSR 60
           MIVLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSR
Sbjct: 1   MIVLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSR 60

Query: 61  TPYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPP 120
           TPYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPP
Sbjct: 61  TPYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPP 120

Query: 121 SFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRF 180
           SFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRF
Sbjct: 121 SFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRF 180

Query: 181 AELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRV 240
           AELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRV
Sbjct: 181 AELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRV 240

Query: 241 LDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRAREL 300
           LDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRAREL
Sbjct: 241 LDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRAREL 300

Query: 301 FGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISF 360
           FGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISF
Sbjct: 301 FGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISF 360

Query: 361 STVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAP 420
           STVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAP
Sbjct: 361 STVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAP 420

Query: 421 LDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGA 480
           LDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGA
Sbjct: 421 LDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGA 480

Query: 481 YIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFS 540
           YIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFS
Sbjct: 481 YIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFS 540

Query: 541 FQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLL 600
           FQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLL
Sbjct: 541 FQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLL 600

Query: 601 TRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEV 660
           TRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEV
Sbjct: 601 TRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEV 660

Query: 661 RDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILII 720
           RDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILII
Sbjct: 661 RDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILII 720

Query: 721 ALGSVSFIFLLAMIVLAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARARKK 780
           ALGSVSFIFLLAMIVLAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARARKK
Sbjct: 721 ALGSVSFIFLLAMIVLAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARARKK 780

Query: 781 KLSKSDIMLVQSSNVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKTDLMFLKPC 840
           KLSKSDIMLVQSSNVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKTDLMFLKPC
Sbjct: 781 KLSKSDIMLVQSSNVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKTDLMFLKPC 840

Query: 841 SPSRSTDTEHNPCGAIVTGYTDQQPDIISNGSILSNEVRLKRKD 884
           SPSRSTDTEHNPCGAIVTGYTDQQPDIISNGSILSNE + +R +
Sbjct: 841 SPSRSTDTEHNPCGAIVTGYTDQQPDIISNGSILSNETKHQRAE 884


>gi|94538350 protocadherin 17 precursor [Homo sapiens]
          Length = 1159

 Score =  681 bits (1758), Expect = 0.0
 Identities = 385/881 (43%), Positives = 541/881 (61%), Gaps = 82/881 (9%)

Query: 9   LLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDL----GLDITKLSARG------FQTVPN 58
           LLW        L+Y+V EEQ  GT +GNI  D     GL   +    G      ++ + N
Sbjct: 10  LLWAPALTLKNLNYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSKSGSYRVLEN 69

Query: 59  SRTPYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDN 118
           S    LD++ ++G+LY  ++IDRE +C+ +  C L LEVF  N  E+  +++E+ DINDN
Sbjct: 70  SAPHLLDVDADSGLLYTKQRIDRESLCRHNAKCQLSLEVFA-NDKEICMIKVEIQDINDN 128

Query: 119 PPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSY--FSLDVQTQGD 176
            PSF    + ++ISE+A PGTRFPL SA DPD G N LR Y +T + +  F LDV+++GD
Sbjct: 129 APSFSSDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFGLDVKSRGD 188

Query: 177 GNRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALL 236
           G +F ELV++K LDREQQ  H  VLTA+DGG                 PP   R+ T  +
Sbjct: 189 GTKFPELVIQKALDREQQNHHTLVLTALDGGE----------------PP---RSATVQI 229

Query: 237 TIRVLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPR 296
            ++V+DSNDN P F+ P Y V LPEN+P GT+VI LNATD DEG NGEV+YSFSS++  R
Sbjct: 230 NVKVIDSNDNSPVFEAPSYLVELPENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDR 289

Query: 297 ARELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAP 356
            RELF + P+TG + V G LDYEE+ + ++ VQA+DLGPN +PAHCKV V+++D NDNAP
Sbjct: 290 VRELFSIDPKTGLIRVKGNLDYEENGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAP 349

Query: 357 EISFSTVKE-AVSEGAAPGTVVALFSVTDRDSEENGQVQCELLG---------------D 400
            I F +V++ A+SE A PGTV+AL  VTDRDS +NGQ+QC +LG                
Sbjct: 350 SIGFVSVRQGALSEAAPPGTVIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGS 409

Query: 401 VPFRLKSSFKNYYTIVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNA 460
           VPF+L+ ++ N+YT+VT+ PLDRE  D Y +T+VARD G P L+++KS  +++ D NDN 
Sbjct: 410 VPFKLEENYDNFYTVVTDRPLDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNP 469

Query: 461 PRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINS 520
           PRF++ +Y + V ENN+PG Y+ +V A D D G N  ++YSIL   I  +S++TYVS+N 
Sbjct: 470 PRFTKGLYVLQVHENNIPGEYLGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVSVNP 529

Query: 521 ENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPG 580
            NG +YALRSF++EQ K F F+V A+D+G+P  L  NATV + ++D NDNAP IV  LP 
Sbjct: 530 TNGAIYALRSFNFEQTKAFEFKVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIV--LPT 587

Query: 581 RNGTPAREVLPRSAEPGYLLTRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRT 640
                A   +PR+A  GYL++ V A+D+D GE+ RLTY IV GN+ +LF +D  +GE+RT
Sbjct: 588 LQNDTAELQVPRNAGLGYLVSTVRALDSDFGESGRLTYEIVDGNDDHLFEIDPSSGEIRT 647

Query: 641 ARRVPAKRDPQRPYELVIEVRDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQ 700
               P   D     ELV++V DHG+P LS+ A L+++ V G++ P+G             
Sbjct: 648 LH--PFWEDVTPVVELVVKVTDHGKPTLSAVAKLIIRSVSGSL-PEG------------- 691

Query: 701 RPSRSGGGETSLDLTLILIIALGSVSFIFLLAMIVLAVRCQKE-KKLNIYTCLASDCCLC 759
              R  G +   D++L LI+ L ++S I L AMI +AV+C++E K++  Y C  ++    
Sbjct: 692 -VPRVNGEQHHWDMSLPLIVTLSTISIILLAAMITIAVKCKRENKEIRTYNCRIAE--YS 748

Query: 760 CCCCGGGGSTCCGRQARARKKKLSKSDIMLVQSSNVPSNPAQV-PIEESGGFGSHHHNQN 818
               GGG         + +KKK++K+DIMLVQS     N   V  +  S    +      
Sbjct: 749 HPQLGGG---------KGKKKKINKNDIMLVQSEVEERNAMNVMNVVSSPSLAT--SPMY 797

Query: 819 YCYQVCLTPESAKTDLMFLKPCSPSRSTDTEHNPCGAIVTG 859
           + YQ  L   S ++++M+LKP S + +    H  C    TG
Sbjct: 798 FDYQTRLPLSSPRSEVMYLKPASNNLTVPQGHAGCHTSFTG 838


>gi|157426847 protocadherin 19 isoform a [Homo sapiens]
          Length = 1101

 Score =  657 bits (1695), Expect = 0.0
 Identities = 379/879 (43%), Positives = 536/879 (60%), Gaps = 76/879 (8%)

Query: 3   VLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDL---GLDITKLSARGFQTVPNS 59
           VLLL A+LW        L Y+V+EEQ  GT + N+A+D    G  +    A  F+ V NS
Sbjct: 8   VLLLLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQASAFRVVSNS 67

Query: 60  RTPYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNP 119
               +D+N  +G+L   +KIDR+ +C+QSP C++ LEV + + +E+  +++E+ D+NDN 
Sbjct: 68  APHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEV-MSSSMEICVIKVEIKDLNDNA 126

Query: 120 PSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNR 179
           PSFP   + +EISE+A+PGTR PL+SA+DPD G+  ++ YE+TPN  F L+++T+GDG+R
Sbjct: 127 PSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKTRGDGSR 186

Query: 180 FAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIR 239
           FAELV+EK LDRE Q+ + + +TA+DGG                 PP   R GT  L+I+
Sbjct: 187 FAELVVEKSLDRETQSHYSFRITALDGGD----------------PP---RLGTVGLSIK 227

Query: 240 VLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARE 299
           V DSNDN P F +  Y VS+PENSPP T VI+LNA+DPDEG NG+VVYSF  +++ R RE
Sbjct: 228 VTDSNDNNPVFSESTYAVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRE 287

Query: 300 LFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEIS 359
           LF + P +G + V+G LDYEE  VY++ VQAKDLGPN++PAHCKV V VLD NDN P I+
Sbjct: 288 LFQIDPHSGLVTVTGALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVIN 347

Query: 360 FSTVKE---AVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIV 416
             +V      VSE A PG V+AL  V+DRDS  NG+VQC LLG+VPFRL+  ++++ TI+
Sbjct: 348 LLSVNSELVEVSESAPPGYVIALVRVSDRDSGLNGRVQCRLLGNVPFRLQ-EYESFSTIL 406

Query: 417 TEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENN 476
            +  LDRE  D Y LT+ ARD G P L ++KS  V ++D NDN P FS+P Y V V ENN
Sbjct: 407 VDGRLDREQHDQYNLTIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENN 466

Query: 477 VPGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQL 536
            PGAY+ +VSA D D G N  ++Y I+  Q++ M VFTYVSIN  +G +YALRSF++EQ 
Sbjct: 467 TPGAYLLSVSARDPDLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQT 526

Query: 537 KDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEP 596
           K F F+V A+D G P +L  NATV ++I+D NDN P I AP P  NGT A   +PR++  
Sbjct: 527 KAFEFKVLAKDGGLP-SLQSNATVRVIILDVNDNTPVITAP-PLINGT-AEVYIPRNSGI 583

Query: 597 GYLLTRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYEL 656
           GYL+T V A D D+GEN R+TY +  G +   F +D   GE+RT R        +  YEL
Sbjct: 584 GYLVTVVKAEDYDEGENGRVTYDMTEG-DRGFFEIDQVNGEVRTTRTF--GESSKSSYEL 640

Query: 657 VIEVRDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTL 716
           ++   DHG+  LS++A +++ L   A++ Q   G                    S++L+L
Sbjct: 641 IVVAHDHGKTSLSASALVLIYL-SPALDAQESMG--------------------SVNLSL 679

Query: 717 ILIIALGSVSFIFLLAMIVLAVRCQKE-KKLNIYTCLASDCCLCCCCCGGGGSTCCGRQA 775
           I IIALGS++ I  + MI +A++C+++ K++  Y C  ++                G Q 
Sbjct: 680 IFIIALGSIAGILFVTMIFVAIKCKRDNKEIRTYNCRIAEYSY-------------GHQK 726

Query: 776 R-ARKKKLSKSDIMLVQSSNVPSNPAQVPIEESGGFGSHHHNQNY--CYQVCLTPESAKT 832
           + ++KKK+SK+DI L     VP +  +          S   + NY   +Q  L     ++
Sbjct: 727 KSSKKKKISKNDIRL-----VPRDVEETDKMNVVSCSSLTSSLNYFDYHQQTLPLGCRRS 781

Query: 833 DLMFLKPCSPSRSTDTEHNPCGAIVTGYTDQQPDIISNG 871
           +  FL   + +    + ++           QQPD+I NG
Sbjct: 782 ESTFLNVENQNTRNTSANHIYHHSFNSQGPQQPDLIING 820


>gi|157426845 protocadherin 19 isoform b [Homo sapiens]
          Length = 1100

 Score =  657 bits (1695), Expect = 0.0
 Identities = 379/879 (43%), Positives = 536/879 (60%), Gaps = 76/879 (8%)

Query: 3   VLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDL---GLDITKLSARGFQTVPNS 59
           VLLL A+LW        L Y+V+EEQ  GT + N+A+D    G  +    A  F+ V NS
Sbjct: 8   VLLLLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQASAFRVVSNS 67

Query: 60  RTPYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNP 119
               +D+N  +G+L   +KIDR+ +C+QSP C++ LEV + + +E+  +++E+ D+NDN 
Sbjct: 68  APHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEV-MSSSMEICVIKVEIKDLNDNA 126

Query: 120 PSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNR 179
           PSFP   + +EISE+A+PGTR PL+SA+DPD G+  ++ YE+TPN  F L+++T+GDG+R
Sbjct: 127 PSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKTRGDGSR 186

Query: 180 FAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIR 239
           FAELV+EK LDRE Q+ + + +TA+DGG                 PP   R GT  L+I+
Sbjct: 187 FAELVVEKSLDRETQSHYSFRITALDGGD----------------PP---RLGTVGLSIK 227

Query: 240 VLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARE 299
           V DSNDN P F +  Y VS+PENSPP T VI+LNA+DPDEG NG+VVYSF  +++ R RE
Sbjct: 228 VTDSNDNNPVFSESTYAVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRE 287

Query: 300 LFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEIS 359
           LF + P +G + V+G LDYEE  VY++ VQAKDLGPN++PAHCKV V VLD NDN P I+
Sbjct: 288 LFQIDPHSGLVTVTGALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVIN 347

Query: 360 FSTVKE---AVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIV 416
             +V      VSE A PG V+AL  V+DRDS  NG+VQC LLG+VPFRL+  ++++ TI+
Sbjct: 348 LLSVNSELVEVSESAPPGYVIALVRVSDRDSGLNGRVQCRLLGNVPFRLQ-EYESFSTIL 406

Query: 417 TEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENN 476
            +  LDRE  D Y LT+ ARD G P L ++KS  V ++D NDN P FS+P Y V V ENN
Sbjct: 407 VDGRLDREQHDQYNLTIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENN 466

Query: 477 VPGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQL 536
            PGAY+ +VSA D D G N  ++Y I+  Q++ M VFTYVSIN  +G +YALRSF++EQ 
Sbjct: 467 TPGAYLLSVSARDPDLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQT 526

Query: 537 KDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEP 596
           K F F+V A+D G P +L  NATV ++I+D NDN P I AP P  NGT A   +PR++  
Sbjct: 527 KAFEFKVLAKDGGLP-SLQSNATVRVIILDVNDNTPVITAP-PLINGT-AEVYIPRNSGI 583

Query: 597 GYLLTRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYEL 656
           GYL+T V A D D+GEN R+TY +  G +   F +D   GE+RT R        +  YEL
Sbjct: 584 GYLVTVVKAEDYDEGENGRVTYDMTEG-DRGFFEIDQVNGEVRTTRTF--GESSKSSYEL 640

Query: 657 VIEVRDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTL 716
           ++   DHG+  LS++A +++ L   A++ Q   G                    S++L+L
Sbjct: 641 IVVAHDHGKTSLSASALVLIYL-SPALDAQESMG--------------------SVNLSL 679

Query: 717 ILIIALGSVSFIFLLAMIVLAVRCQKE-KKLNIYTCLASDCCLCCCCCGGGGSTCCGRQA 775
           I IIALGS++ I  + MI +A++C+++ K++  Y C  ++                G Q 
Sbjct: 680 IFIIALGSIAGILFVTMIFVAIKCKRDNKEIRTYNCRIAEYSY-------------GHQK 726

Query: 776 R-ARKKKLSKSDIMLVQSSNVPSNPAQVPIEESGGFGSHHHNQNY--CYQVCLTPESAKT 832
           + ++KKK+SK+DI L     VP +  +          S   + NY   +Q  L     ++
Sbjct: 727 KSSKKKKISKNDIRL-----VPRDVEETDKMNVVSCSSLTSSLNYFDYHQQTLPLGCRRS 781

Query: 833 DLMFLKPCSPSRSTDTEHNPCGAIVTGYTDQQPDIISNG 871
           +  FL   + +    + ++           QQPD+I NG
Sbjct: 782 ESTFLNVENQNTRNTSANHIYHHSFNSQGPQQPDLIING 820


>gi|14165431 protocadherin alpha subfamily C, 2 isoform 2 precursor
           [Homo sapiens]
          Length = 884

 Score =  654 bits (1688), Expect = 0.0
 Identities = 377/896 (42%), Positives = 538/896 (60%), Gaps = 80/896 (8%)

Query: 1   MIVLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSR 60
           ++ LLL  LL +     SQL Y+V EEQ  G  VGN+A  LGL++ +L   G   + +  
Sbjct: 25  LLPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGP-GCLRINHLG 83

Query: 61  TP---YLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDIND 117
            P   YL+L+L +G L+VNE+IDRE +C+Q P C+L LEV   NP+ +  VE+E+LDIND
Sbjct: 84  APSPRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDIND 143

Query: 118 NPPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDG 177
           N P FP P+  +++SES  PG RF +ESA DPDVG NS++ YE++P+ +F LD++   + 
Sbjct: 144 NSPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQEN 203

Query: 178 NRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLT 237
           ++  ELVL K LDREQ A+H  VLTAVDGG                +P    R+GTA ++
Sbjct: 204 SKVLELVLRKGLDREQAALHHLVLTAVDGG----------------IPA---RSGTAQIS 244

Query: 238 IRVLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRA 297
           +RVLD+NDN PAFDQ  Y V L E+SPPGTLV++LNA+DPDEG NGE+ YS SS+ S R 
Sbjct: 245 VRVLDTNDNSPAFDQSTYRVQLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRE 304

Query: 298 RELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPE 357
           R+LF +   TG + V G LDYEE+  YQ+YVQA D GP  +  HCKVLV ++D NDNAPE
Sbjct: 305 RQLFSIDASTGEVRVIGGLDYEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPE 364

Query: 358 ISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVT 417
           +  + +   V E A P T+VA+ SV D+DS  N +V   L   +PFRL + F N YT+V 
Sbjct: 365 VVLTDLYSPVPENATPNTIVAVLSVNDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVV 423

Query: 418 EAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNV 477
             PLDRE    Y +TV A D G P L++ ++++V++SD+NDN P F +  Y +Y+ ENN+
Sbjct: 424 SGPLDRERVAVYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNL 483

Query: 478 PGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLK 537
           PG  +  V ATD DE  NA++ YS+LE +IQG+ V +YVSINS +G LYA+ SFDYE+ +
Sbjct: 484 PGVLLCTVQATDPDEKENAEVTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFR 543

Query: 538 DFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPG 597
           +F   VEA+D GSP  L+   T N+ +VD ND+AP I+ P    N + A E++PR+A  G
Sbjct: 544 EFFVTVEAQDKGSP-PLSSTVTANVYVVDMNDHAPHILYP-TSTNSSAAFEMVPRTAPAG 601

Query: 598 YLLTRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELV 657
           YL+T+V A+D+D G+NA L Y + + ++++LF+++  TGE+RT R++    +    + L 
Sbjct: 602 YLVTKVIAMDSDSGQNAWLFYHLAQTSDLDLFKVELHTGEIRTTRKM--GDESGSTFNLT 659

Query: 658 IEVRDHGQPPLSSTATLVVQLVD--GAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLT 715
           + VRD+G+P LS++  + V +VD    + P            + QR  +S    T  ++T
Sbjct: 660 VVVRDNGEPSLSASVAITVAVVDRVSKILP------------DTQRHVKS--PRTYSEIT 705

Query: 716 LILIIALGSVSFIFLLAMIVLA-VRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQ 774
           L LIIAL +VSFIFLL +I+L+ ++C +      YT   + CC        GG      +
Sbjct: 706 LYLIIALSTVSFIFLLTIIILSIIKCYR------YTAYGTACC--------GGFCGVRER 751

Query: 775 ARARKKKLSKSDIMLVQSSNVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKTDL 834
           + A   K + ++I       +   P  + +  +G        + YCY+ CLT  S     
Sbjct: 752 SPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSL-----TKTYCYKACLTAGSGSDTF 806

Query: 835 MFLKPCSPSRSTDTEHNPCGA--------IVTGYTDQQPD---IISNGSILSNEVR 879
           MF      +    T   P GA         +TG + Q      I+ N ++  NEVR
Sbjct: 807 MFY-----NTGAQTGPGPSGAQAAVTDSRNLTGQSGQNAGNLIILKNEAVSQNEVR 857


>gi|9256600 protocadherin alpha subfamily C, 2 isoform 1 precursor
           [Homo sapiens]
          Length = 1007

 Score =  654 bits (1686), Expect = 0.0
 Identities = 378/906 (41%), Positives = 540/906 (59%), Gaps = 80/906 (8%)

Query: 1   MIVLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSR 60
           ++ LLL  LL +     SQL Y+V EEQ  G  VGN+A  LGL++ +L   G   + +  
Sbjct: 25  LLPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGP-GCLRINHLG 83

Query: 61  TP---YLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDIND 117
            P   YL+L+L +G L+VNE+IDRE +C+Q P C+L LEV   NP+ +  VE+E+LDIND
Sbjct: 84  APSPRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDIND 143

Query: 118 NPPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDG 177
           N P FP P+  +++SES  PG RF +ESA DPDVG NS++ YE++P+ +F LD++   + 
Sbjct: 144 NSPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQEN 203

Query: 178 NRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLT 237
           ++  ELVL K LDREQ A+H  VLTAVDGG                +P    R+GTA ++
Sbjct: 204 SKVLELVLRKGLDREQAALHHLVLTAVDGG----------------IPA---RSGTAQIS 244

Query: 238 IRVLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRA 297
           +RVLD+NDN PAFDQ  Y V L E+SPPGTLV++LNA+DPDEG NGE+ YS SS+ S R 
Sbjct: 245 VRVLDTNDNSPAFDQSTYRVQLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRE 304

Query: 298 RELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPE 357
           R+LF +   TG + V G LDYEE+  YQ+YVQA D GP  +  HCKVLV ++D NDNAPE
Sbjct: 305 RQLFSIDASTGEVRVIGGLDYEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPE 364

Query: 358 ISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVT 417
           +  + +   V E A P T+VA+ SV D+DS  N +V   L   +PFRL + F N YT+V 
Sbjct: 365 VVLTDLYSPVPENATPNTIVAVLSVNDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVV 423

Query: 418 EAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNV 477
             PLDRE    Y +TV A D G P L++ ++++V++SD+NDN P F +  Y +Y+ ENN+
Sbjct: 424 SGPLDRERVAVYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNL 483

Query: 478 PGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLK 537
           PG  +  V ATD DE  NA++ YS+LE +IQG+ V +YVSINS +G LYA+ SFDYE+ +
Sbjct: 484 PGVLLCTVQATDPDEKENAEVTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFR 543

Query: 538 DFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPG 597
           +F   VEA+D GSP  L+   T N+ +VD ND+AP I+ P    N + A E++PR+A  G
Sbjct: 544 EFFVTVEAQDKGSP-PLSSTVTANVYVVDMNDHAPHILYP-TSTNSSAAFEMVPRTAPAG 601

Query: 598 YLLTRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELV 657
           YL+T+V A+D+D G+NA L Y + + ++++LF+++  TGE+RT R++    +    + L 
Sbjct: 602 YLVTKVIAMDSDSGQNAWLFYHLAQTSDLDLFKVELHTGEIRTTRKM--GDESGSTFNLT 659

Query: 658 IEVRDHGQPPLSSTATLVVQLVD--GAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLT 715
           + VRD+G+P LS++  + V +VD    + P            + QR  +S    T  ++T
Sbjct: 660 VVVRDNGEPSLSASVAITVAVVDRVSKILP------------DTQRHVKS--PRTYSEIT 705

Query: 716 LILIIALGSVSFIFLLAMIVLA-VRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQ 774
           L LIIAL +VSFIFLL +I+L+ ++C +      YT   + CC        GG      +
Sbjct: 706 LYLIIALSTVSFIFLLTIIILSIIKCYR------YTAYGTACC--------GGFCGVRER 751

Query: 775 ARARKKKLSKSDIMLVQSSNVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKTDL 834
           + A   K + ++I       +   P  + +  +G        + YCY+ CLT  S     
Sbjct: 752 SPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSL-----TKTYCYKACLTAGSGSDTF 806

Query: 835 MFLKPCSPSRSTDTEHNPCGA--------IVTGYTDQQPD---IISNGSILSNEVRLKRK 883
           MF      +    T   P GA         +TG + Q      I+ N ++  NE R    
Sbjct: 807 MFY-----NTGAQTGPGPSGAQAAVTDSRNLTGQSGQNAGNLIILKNEAVSQNEPRQPNP 861

Query: 884 DHHLSS 889
           D   S+
Sbjct: 862 DWRYSA 867


>gi|14277685 protocadherin gamma subfamily C, 5 isoform 2 precursor
           [Homo sapiens]
          Length = 878

 Score =  629 bits (1622), Expect = e-180
 Identities = 358/833 (42%), Positives = 498/833 (59%), Gaps = 62/833 (7%)

Query: 16  VFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRTPYLDLNLETGVLYV 75
           V  QL Y+V EE E GT VGN+A+DLGL +T L +R  Q        Y  L+L +G L V
Sbjct: 27  VSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGALAV 86

Query: 76  NEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPSFPEPDLTVEISESA 135
           N+KIDRE +C  S SC+L ++V  E+PLEL +VE+E+LD+NDN PSF  P+  + ISESA
Sbjct: 87  NQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFATPEREMRISESA 146

Query: 136 TPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAELVLEKPLDREQQA 195
             G RFPL+SA DPDVGTN++  Y ++PNS+FSL+V+T  DG  F ELVLE+ LDRE QA
Sbjct: 147 ASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDREAQA 206

Query: 196 VHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLDSNDNVPAFDQPVY 255
            H+ VLTAVDGG                      R+GT L+++ VLD NDN P F   V 
Sbjct: 207 RHQLVLTAVDGG-------------------TPARSGTTLISVIVLDINDNAPTFQSSVL 247

Query: 256 TVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGLSPRTGRLEVSGE 315
            V +PEN+P GTL+++LNATDPDEG NG++ YSF  H S   R LFGL P +G + V G 
Sbjct: 248 RVGIPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGP 307

Query: 316 LDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFSTVKEAVSEGAAPGT 375
           +D+EES  Y+++ +A+D G  A+  HC + V V D NDNAPE+  +++   V E    GT
Sbjct: 308 IDFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGT 367

Query: 376 VVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLDREAGDSYTLTVVA 435
           VV LF+V DRDS  NG+V  ++  D+PF++K S +N+Y+++T  PLDREA   Y + ++A
Sbjct: 368 VVGLFNVRDRDSGRNGEVSLDISPDLPFQIKPS-ENHYSLLTSQPLDREATSHYIIELLA 426

Query: 436 RDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGAN 495
            D G P+L    +I++ +SDVNDNAPRF+Q +Y  Y+ EN  PG+ +  V+A+D D G N
Sbjct: 427 SDAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDN 486

Query: 496 AQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALA 555
           A+L YSI+  Q+QG    ++V +N E+G ++A R+FDYE L+     V  RD+GSP  L 
Sbjct: 487 ARLTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSP-PLH 545

Query: 556 GNATVNILIVDQNDNAPAIVAPLPG-RNGTPAREVLPRSAEPGYLLTRVAAVDADDGENA 614
            N ++++ ++D+NDNAPA++ P P   +  P R  LPRSA PG L+T+V AVDAD G NA
Sbjct: 546 ANTSLHVFVLDENDNAPAVLHPRPDWEHSAPQR--LPRSAPPGSLVTKVTAVDADAGHNA 603

Query: 615 RLTYSIV-RGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSSTAT 673
            L+YS++ +     LF +   TGE+RTAR +    D     ++V+ VRD+G P LSSTAT
Sbjct: 604 WLSYSLLPQSTAPGLFLVSTHTGEVRTARAL--LEDDSDTQQVVVLVRDNGDPSLSSTAT 661

Query: 674 LVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILIIALGSVSFIFLLAM 733
           +++ L D   E                 P RS       DLTL LI+AL +VS + L+  
Sbjct: 662 VLLVLEDEDPEEM-----PKSSDFLIHPPERS-------DLTLYLIVALATVSLLSLVTF 709

Query: 734 IVLAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARARKKKLSKSDIMLVQSS 793
             L+ +C +                      GGG  CC RQ         +S   L  SS
Sbjct: 710 TFLSAKCLQGNADG----------------DGGGGQCCRRQDSPSPDFYKQSSPNLQVSS 753

Query: 794 NVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKTDLMFLKPCSPSRST 846
           +      +V +  +        +Q++CY+ C +P S  +D  FL+P S  + T
Sbjct: 754 DGTLKYMEVTLRPT-------DSQSHCYRTCFSPASDGSDFTFLRPLSVQQPT 799


>gi|11128023 protocadherin gamma subfamily C, 5 isoform 1 precursor
           [Homo sapiens]
          Length = 944

 Score =  629 bits (1622), Expect = e-180
 Identities = 358/833 (42%), Positives = 498/833 (59%), Gaps = 62/833 (7%)

Query: 16  VFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRTPYLDLNLETGVLYV 75
           V  QL Y+V EE E GT VGN+A+DLGL +T L +R  Q        Y  L+L +G L V
Sbjct: 27  VSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGALAV 86

Query: 76  NEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPSFPEPDLTVEISESA 135
           N+KIDRE +C  S SC+L ++V  E+PLEL +VE+E+LD+NDN PSF  P+  + ISESA
Sbjct: 87  NQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFATPEREMRISESA 146

Query: 136 TPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAELVLEKPLDREQQA 195
             G RFPL+SA DPDVGTN++  Y ++PNS+FSL+V+T  DG  F ELVLE+ LDRE QA
Sbjct: 147 ASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDREAQA 206

Query: 196 VHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLDSNDNVPAFDQPVY 255
            H+ VLTAVDGG                      R+GT L+++ VLD NDN P F   V 
Sbjct: 207 RHQLVLTAVDGG-------------------TPARSGTTLISVIVLDINDNAPTFQSSVL 247

Query: 256 TVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGLSPRTGRLEVSGE 315
            V +PEN+P GTL+++LNATDPDEG NG++ YSF  H S   R LFGL P +G + V G 
Sbjct: 248 RVGIPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGP 307

Query: 316 LDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFSTVKEAVSEGAAPGT 375
           +D+EES  Y+++ +A+D G  A+  HC + V V D NDNAPE+  +++   V E    GT
Sbjct: 308 IDFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGT 367

Query: 376 VVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLDREAGDSYTLTVVA 435
           VV LF+V DRDS  NG+V  ++  D+PF++K S +N+Y+++T  PLDREA   Y + ++A
Sbjct: 368 VVGLFNVRDRDSGRNGEVSLDISPDLPFQIKPS-ENHYSLLTSQPLDREATSHYIIELLA 426

Query: 436 RDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGAN 495
            D G P+L    +I++ +SDVNDNAPRF+Q +Y  Y+ EN  PG+ +  V+A+D D G N
Sbjct: 427 SDAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDN 486

Query: 496 AQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALA 555
           A+L YSI+  Q+QG    ++V +N E+G ++A R+FDYE L+     V  RD+GSP  L 
Sbjct: 487 ARLTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSP-PLH 545

Query: 556 GNATVNILIVDQNDNAPAIVAPLPG-RNGTPAREVLPRSAEPGYLLTRVAAVDADDGENA 614
            N ++++ ++D+NDNAPA++ P P   +  P R  LPRSA PG L+T+V AVDAD G NA
Sbjct: 546 ANTSLHVFVLDENDNAPAVLHPRPDWEHSAPQR--LPRSAPPGSLVTKVTAVDADAGHNA 603

Query: 615 RLTYSIV-RGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSSTAT 673
            L+YS++ +     LF +   TGE+RTAR +    D     ++V+ VRD+G P LSSTAT
Sbjct: 604 WLSYSLLPQSTAPGLFLVSTHTGEVRTARAL--LEDDSDTQQVVVLVRDNGDPSLSSTAT 661

Query: 674 LVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILIIALGSVSFIFLLAM 733
           +++ L D   E                 P RS       DLTL LI+AL +VS + L+  
Sbjct: 662 VLLVLEDEDPEEM-----PKSSDFLIHPPERS-------DLTLYLIVALATVSLLSLVTF 709

Query: 734 IVLAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARARKKKLSKSDIMLVQSS 793
             L+ +C +                      GGG  CC RQ         +S   L  SS
Sbjct: 710 TFLSAKCLQGNADG----------------DGGGGQCCRRQDSPSPDFYKQSSPNLQVSS 753

Query: 794 NVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKTDLMFLKPCSPSRST 846
           +      +V +  +        +Q++CY+ C +P S  +D  FL+P S  + T
Sbjct: 754 DGTLKYMEVTLRPT-------DSQSHCYRTCFSPASDGSDFTFLRPLSVQQPT 799


>gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens]
          Length = 936

 Score =  613 bits (1580), Expect = e-175
 Identities = 330/800 (41%), Positives = 485/800 (60%), Gaps = 36/800 (4%)

Query: 3   VLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRTP 62
           +LLL+ LL   +    QLHY++ EE +HGTFVG IA+DLGL++ +L  R F+     R  
Sbjct: 13  LLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGD 72

Query: 63  YLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPSF 122
            L++NL+ G+L+VN +IDRE++C++   C +HLEV ++ PL++F VE+ V DINDNPP F
Sbjct: 73  LLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAVKDINDNPPRF 132

Query: 123 PEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAE 182
              +  + I ES  P +RFPLE A D D+G N+   Y + PN YF LDV+T  +   F E
Sbjct: 133 SRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVKTNEEETNFLE 192

Query: 183 LVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLD 242
           LVL K LDRE+   HR ++ A DGG                   + + TGT  L I VLD
Sbjct: 193 LVLRKSLDREETQEHRLLVIATDGG-------------------KPELTGTVQLLINVLD 233

Query: 243 SNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFG 302
           +NDN P FD+ +Y V L EN+P GTLVI+LNA+D DEG N E+VY FS+ +    +  F 
Sbjct: 234 ANDNAPEFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFI 293

Query: 303 LSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFST 362
           ++  TG ++V+GELDYE+   Y++ + A D     +  HCKV+V++LD NDN PE++ +T
Sbjct: 294 INSNTGEIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITT 353

Query: 363 VKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLD 422
           +   V E A   TV+AL SV+DRDS  NGQV C L+  VPF+L S+FKNYY++V ++ LD
Sbjct: 354 LFLPVKEDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALD 413

Query: 423 REAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYI 482
           RE+   Y L V ARD G P+L  + S+ V+V+DVNDNAP F+QP Y V+V ENN PG +I
Sbjct: 414 RESVSVYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHI 473

Query: 483 YAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQ 542
           + VSA D D   NA ++YS++E ++    + +YVS+++E+G +YAL+  D+E+++   FQ
Sbjct: 474 FTVSARDADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQ 533

Query: 543 VEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTR 602
           V ARDAG P  L  N T+ + ++D+NDNAPA++ P  G  G    E++PRS   G+++ +
Sbjct: 534 VSARDAGVP-PLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAK 592

Query: 603 VAAVDADDGENARLTYSI--VRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEV 660
           V AVD D G NA L+Y +    G+    FR+   TGE+ T R +     P+  + L++ V
Sbjct: 593 VRAVDPDSGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPR--HRLLVLV 650

Query: 661 RDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILII 720
           +DHG+PPL++TAT++V LV+    P+    +  G  G              +D+ + LII
Sbjct: 651 KDHGEPPLTATATVLVSLVESGQAPKASSRASAGAVGPE---------AALVDVNVYLII 701

Query: 721 ALGSVSFIFLLAMIV-LAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARARK 779
           A+ +VS + +L +++  A+RC  +    +  C      L C    G  S    R+ R   
Sbjct: 702 AICAVSSLLVLTLLLYTALRCSAQPTEAV--CTRGKPTLLCSSAVGSWSYSQQRRQRVCS 759

Query: 780 KKLSKSDIMLVQSSNVPSNP 799
            +      ++  S ++P  P
Sbjct: 760 GEAPPKTDLMAFSPSLPQGP 779


>gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo
           sapiens]
          Length = 816

 Score =  613 bits (1580), Expect = e-175
 Identities = 330/800 (41%), Positives = 485/800 (60%), Gaps = 36/800 (4%)

Query: 3   VLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRTP 62
           +LLL+ LL   +    QLHY++ EE +HGTFVG IA+DLGL++ +L  R F+     R  
Sbjct: 13  LLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGD 72

Query: 63  YLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPSF 122
            L++NL+ G+L+VN +IDRE++C++   C +HLEV ++ PL++F VE+ V DINDNPP F
Sbjct: 73  LLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAVKDINDNPPRF 132

Query: 123 PEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAE 182
              +  + I ES  P +RFPLE A D D+G N+   Y + PN YF LDV+T  +   F E
Sbjct: 133 SRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVKTNEEETNFLE 192

Query: 183 LVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLD 242
           LVL K LDRE+   HR ++ A DGG                   + + TGT  L I VLD
Sbjct: 193 LVLRKSLDREETQEHRLLVIATDGG-------------------KPELTGTVQLLINVLD 233

Query: 243 SNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFG 302
           +NDN P FD+ +Y V L EN+P GTLVI+LNA+D DEG N E+VY FS+ +    +  F 
Sbjct: 234 ANDNAPEFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFI 293

Query: 303 LSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFST 362
           ++  TG ++V+GELDYE+   Y++ + A D     +  HCKV+V++LD NDN PE++ +T
Sbjct: 294 INSNTGEIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITT 353

Query: 363 VKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLD 422
           +   V E A   TV+AL SV+DRDS  NGQV C L+  VPF+L S+FKNYY++V ++ LD
Sbjct: 354 LFLPVKEDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALD 413

Query: 423 REAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYI 482
           RE+   Y L V ARD G P+L  + S+ V+V+DVNDNAP F+QP Y V+V ENN PG +I
Sbjct: 414 RESVSVYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHI 473

Query: 483 YAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQ 542
           + VSA D D   NA ++YS++E ++    + +YVS+++E+G +YAL+  D+E+++   FQ
Sbjct: 474 FTVSARDADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQ 533

Query: 543 VEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTR 602
           V ARDAG P  L  N T+ + ++D+NDNAPA++ P  G  G    E++PRS   G+++ +
Sbjct: 534 VSARDAGVP-PLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAK 592

Query: 603 VAAVDADDGENARLTYSI--VRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEV 660
           V AVD D G NA L+Y +    G+    FR+   TGE+ T R +     P+  + L++ V
Sbjct: 593 VRAVDPDSGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPR--HRLLVLV 650

Query: 661 RDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILII 720
           +DHG+PPL++TAT++V LV+    P+    +  G  G              +D+ + LII
Sbjct: 651 KDHGEPPLTATATVLVSLVESGQAPKASSRASAGAVGPE---------AALVDVNVYLII 701

Query: 721 ALGSVSFIFLLAMIV-LAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARARK 779
           A+ +VS + +L +++  A+RC  +    +  C      L C    G  S    R+ R   
Sbjct: 702 AICAVSSLLVLTLLLYTALRCSAQPTEAV--CTRGKPTLLCSSAVGSWSYSQQRRQRVCS 759

Query: 780 KKLSKSDIMLVQSSNVPSNP 799
            +      ++  S ++P  P
Sbjct: 760 GEAPPKTDLMAFSPSLPQGP 779


>gi|8850232 protocadherin gamma subfamily A, 12 isoform 1 precursor
           [Homo sapiens]
          Length = 932

 Score =  610 bits (1574), Expect = e-174
 Identities = 359/873 (41%), Positives = 509/873 (58%), Gaps = 88/873 (10%)

Query: 5   LLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRTPYL 64
           +L   LW  E   +Q+ Y+V EE E G+ VG+I+ DLGL+  +L+ RG + +P  RT   
Sbjct: 18  ILLGTLW--ETGCTQIRYSVPEELEKGSRVGDISRDLGLEPRELAERGVRIIPRGRTQLF 75

Query: 65  DLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPSFPE 124
            LN  +G L    +IDRE++C  +  C L+L++ +E+ ++++ VE+EV DINDN P F E
Sbjct: 76  ALNPRSGSLVTAGRIDREELCMGAIKCQLNLDILMEDKVKIYGVEVEVRDINDNAPYFRE 135

Query: 125 PDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAELV 184
            +L ++ISE+A    RFPL  A+DPD+G NSL+ YE++PN++FSL VQ   DG+++ ELV
Sbjct: 136 SELEIKISENAATEMRFPLPHAWDPDIGKNSLQSYELSPNTHFSLIVQNGADGSKYPELV 195

Query: 185 LEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLDSN 244
           L++ LDRE++A H  VLTA DGG                      RTGTA + + VLD+N
Sbjct: 196 LKRALDREEKAAHHLVLTASDGG-------------------DPVRTGTARIRVMVLDAN 236

Query: 245 DNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGLS 304
           DN PAF QP Y  S+PEN   GT ++ +NATDPDEG N EV YSF  ++  +A ++F L 
Sbjct: 237 DNAPAFAQPEYRASVPENLALGTQLLVVNATDPDEGVNAEVRYSFR-YVDDKAAQVFKLD 295

Query: 305 PRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFSTVK 364
             +G +   GELD+EES  YQ+ VQA D       A  KVL+ VLD NDNAPE+  +++ 
Sbjct: 296 CNSGTISTIGELDHEESGFYQMEVQAMDNA--GYSARAKVLITVLDVNDNAPEVVLTSLA 353

Query: 365 EAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLDRE 424
            +V E +  GT++AL +V D+DSEENGQV C + G++PF+L+ S+ NYY++VT+  LDRE
Sbjct: 354 SSVPENSPRGTLIALLNVNDQDSEENGQVICFIQGNLPFKLEKSYGNYYSLVTDIVLDRE 413

Query: 425 AGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYA 484
              SY +TV A DRG P LST   I + V+D NDN P F Q  Y  Y+ ENN  G  + +
Sbjct: 414 QVPSYNITVTATDRGTPPLSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGVSLVS 473

Query: 485 VSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQVE 544
           V+A D D   NAQ+ YS+ E  IQG S+ +YVSINS+ G LYAL SFDYEQ +D   +V 
Sbjct: 474 VTAHDPDCEENAQITYSLAENTIQGASLSSYVSINSDTGVLYALSSFDYEQFRDLQVKVM 533

Query: 545 ARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTRVA 604
           ARD G P  L+ N ++++ ++DQNDNAP I+ P    +G+   E+ PRSAEPGYL+T+V 
Sbjct: 534 ARDNGHP-PLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVV 592

Query: 605 AVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVRDHG 664
           AVD D G+NA L+Y +++ +E  LF +   TGE+RTAR +   RD  +   LV+ V+DHG
Sbjct: 593 AVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARAL-LDRDALK-QSLVVAVQDHG 650

Query: 665 QPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILIIALGS 724
           QPPLS+T TL V + D   +     GS        + P+ S   ETS DLTL L++A+ +
Sbjct: 651 QPPLSATVTLTVAVADSIPQVLADLGS-------LESPANS---ETS-DLTLYLVVAVAA 699

Query: 725 VSFIFLLAMIVLAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARARKKKLSK 784
           VS +FL  +I+L                                         R ++  K
Sbjct: 700 VSCVFLAFVILLLA--------------------------------------LRLRRWHK 721

Query: 785 SDIMLVQSSNVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKTDLMFLKPCSPSR 844
           S ++      +   PA   +   G  G     Q Y ++V LT +S K+ L+F +P     
Sbjct: 722 SRLLQASGGGLTGAPASHFV---GVDGVQAFLQTYSHEVSLTTDSRKSHLIFPQPNYADM 778

Query: 845 STDTEHNPCGAIVTGYTDQQPDIISNGSILSNE 877
               E          +   +P ++S  S+ S +
Sbjct: 779 LVSQE---------SFEKSEPLLLSGDSVFSKD 802


>gi|14196457 protocadherin gamma subfamily A, 12 isoform 2 precursor
           [Homo sapiens]
          Length = 820

 Score =  610 bits (1574), Expect = e-174
 Identities = 359/873 (41%), Positives = 509/873 (58%), Gaps = 88/873 (10%)

Query: 5   LLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRTPYL 64
           +L   LW  E   +Q+ Y+V EE E G+ VG+I+ DLGL+  +L+ RG + +P  RT   
Sbjct: 18  ILLGTLW--ETGCTQIRYSVPEELEKGSRVGDISRDLGLEPRELAERGVRIIPRGRTQLF 75

Query: 65  DLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPSFPE 124
            LN  +G L    +IDRE++C  +  C L+L++ +E+ ++++ VE+EV DINDN P F E
Sbjct: 76  ALNPRSGSLVTAGRIDREELCMGAIKCQLNLDILMEDKVKIYGVEVEVRDINDNAPYFRE 135

Query: 125 PDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAELV 184
            +L ++ISE+A    RFPL  A+DPD+G NSL+ YE++PN++FSL VQ   DG+++ ELV
Sbjct: 136 SELEIKISENAATEMRFPLPHAWDPDIGKNSLQSYELSPNTHFSLIVQNGADGSKYPELV 195

Query: 185 LEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLDSN 244
           L++ LDRE++A H  VLTA DGG                      RTGTA + + VLD+N
Sbjct: 196 LKRALDREEKAAHHLVLTASDGG-------------------DPVRTGTARIRVMVLDAN 236

Query: 245 DNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGLS 304
           DN PAF QP Y  S+PEN   GT ++ +NATDPDEG N EV YSF  ++  +A ++F L 
Sbjct: 237 DNAPAFAQPEYRASVPENLALGTQLLVVNATDPDEGVNAEVRYSFR-YVDDKAAQVFKLD 295

Query: 305 PRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFSTVK 364
             +G +   GELD+EES  YQ+ VQA D       A  KVL+ VLD NDNAPE+  +++ 
Sbjct: 296 CNSGTISTIGELDHEESGFYQMEVQAMDNA--GYSARAKVLITVLDVNDNAPEVVLTSLA 353

Query: 365 EAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLDRE 424
            +V E +  GT++AL +V D+DSEENGQV C + G++PF+L+ S+ NYY++VT+  LDRE
Sbjct: 354 SSVPENSPRGTLIALLNVNDQDSEENGQVICFIQGNLPFKLEKSYGNYYSLVTDIVLDRE 413

Query: 425 AGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYA 484
              SY +TV A DRG P LST   I + V+D NDN P F Q  Y  Y+ ENN  G  + +
Sbjct: 414 QVPSYNITVTATDRGTPPLSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGVSLVS 473

Query: 485 VSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQVE 544
           V+A D D   NAQ+ YS+ E  IQG S+ +YVSINS+ G LYAL SFDYEQ +D   +V 
Sbjct: 474 VTAHDPDCEENAQITYSLAENTIQGASLSSYVSINSDTGVLYALSSFDYEQFRDLQVKVM 533

Query: 545 ARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTRVA 604
           ARD G P  L+ N ++++ ++DQNDNAP I+ P    +G+   E+ PRSAEPGYL+T+V 
Sbjct: 534 ARDNGHP-PLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVV 592

Query: 605 AVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVRDHG 664
           AVD D G+NA L+Y +++ +E  LF +   TGE+RTAR +   RD  +   LV+ V+DHG
Sbjct: 593 AVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARAL-LDRDALK-QSLVVAVQDHG 650

Query: 665 QPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILIIALGS 724
           QPPLS+T TL V + D   +     GS        + P+ S   ETS DLTL L++A+ +
Sbjct: 651 QPPLSATVTLTVAVADSIPQVLADLGS-------LESPANS---ETS-DLTLYLVVAVAA 699

Query: 725 VSFIFLLAMIVLAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARARKKKLSK 784
           VS +FL  +I+L                                         R ++  K
Sbjct: 700 VSCVFLAFVILLLA--------------------------------------LRLRRWHK 721

Query: 785 SDIMLVQSSNVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKTDLMFLKPCSPSR 844
           S ++      +   PA   +   G  G     Q Y ++V LT +S K+ L+F +P     
Sbjct: 722 SRLLQASGGGLTGAPASHFV---GVDGVQAFLQTYSHEVSLTTDSRKSHLIFPQPNYADM 778

Query: 845 STDTEHNPCGAIVTGYTDQQPDIISNGSILSNE 877
               E          +   +P ++S  S+ S +
Sbjct: 779 LVSQE---------SFEKSEPLLLSGDSVFSKD 802


>gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo
           sapiens]
          Length = 789

 Score =  608 bits (1568), Expect = e-174
 Identities = 339/802 (42%), Positives = 488/802 (60%), Gaps = 38/802 (4%)

Query: 3   VLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRTP 62
           +LL   +L   E    QLHY+V EE +HG FVG IA+DLGL++ +L  R F+ V   R  
Sbjct: 14  LLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCKFRGD 73

Query: 63  YLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPSF 122
            L++NL+ G+L+VN +IDRE++C +S  C +HLEV +E PL++F V++EV DINDNPP F
Sbjct: 74  LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDNPPVF 133

Query: 123 PEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAE 182
           P     + I+ES    +RFPLE A D D+G N+L  Y ++PN YF LDV T     +   
Sbjct: 134 PATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLG 193

Query: 183 LVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLD 242
           LVL K LDRE+      +LTA DGG                   + + TGT  L I VLD
Sbjct: 194 LVLRKLLDREETPELHLLLTATDGG-------------------KPELTGTVQLLITVLD 234

Query: 243 SNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFG 302
           +NDN P FD+ +YTV LPEN   GTLVI  NA+D DEG NG+++YSFSS +SP  +  F 
Sbjct: 235 NNDNAPVFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFH 294

Query: 303 LSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFST 362
           + P +G + V G +D+EES  +++ V+A D G   +  HC VLV V+D NDNAP+++ ++
Sbjct: 295 MDPLSGAITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTS 354

Query: 363 VKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLD 422
           +   + E A PGTV+ L SV DRD   NGQV C L   VPF+L S+FKNYY++V ++ LD
Sbjct: 355 LSLPIPEDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALD 414

Query: 423 REAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYI 482
           RE+  +Y L V ARD G P+L  + S+ V+V+DVNDNAP F+QP Y V+V ENN PG +I
Sbjct: 415 RESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHI 474

Query: 483 YAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQ 542
           + VSA D D   NA ++YS++E ++   ++ +YVS+++E+G +YAL+  D+E+L+   FQ
Sbjct: 475 FTVSAGDADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQ 534

Query: 543 VEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTR 602
           V ARDAG P  L  N T+ + ++D+NDNAPA++AP  G  G   RE++PRS   G+++ +
Sbjct: 535 VSARDAGVP-PLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAK 593

Query: 603 VAAVDADDGENARLTYSI--VRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEV 660
           V AVDAD G NA L+Y +  V       FR+   TGE+ T R +     P+  + L++ V
Sbjct: 594 VRAVDADSGYNAWLSYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPR--HRLLVLV 651

Query: 661 RDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSL-DLTLILI 719
           +DHG+P L++TAT++V LV+    P+    +  G            G ET L D+ + LI
Sbjct: 652 KDHGEPSLTATATVLVSLVESGQAPKASSRASLG----------IAGPETELVDVNVYLI 701

Query: 720 IALGSVSFIFLLAMIV-LAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARAR 778
           IA+ +VS + +L +++  A+RC         + L     +C    G    +   RQ    
Sbjct: 702 IAICAVSSLLVLTLLLYTALRCSAPSSEGACS-LVKPTLVCSSAVGSWSFSQQRRQRVCS 760

Query: 779 KKKLSKSDIMLVQSSNVPSNPA 800
            +   K+D+M   S ++P  P+
Sbjct: 761 GEGPPKTDLMAF-SPSLPQGPS 781


>gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens]
          Length = 937

 Score =  608 bits (1568), Expect = e-174
 Identities = 339/802 (42%), Positives = 488/802 (60%), Gaps = 38/802 (4%)

Query: 3   VLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRTP 62
           +LL   +L   E    QLHY+V EE +HG FVG IA+DLGL++ +L  R F+ V   R  
Sbjct: 14  LLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCKFRGD 73

Query: 63  YLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPSF 122
            L++NL+ G+L+VN +IDRE++C +S  C +HLEV +E PL++F V++EV DINDNPP F
Sbjct: 74  LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDNPPVF 133

Query: 123 PEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAE 182
           P     + I+ES    +RFPLE A D D+G N+L  Y ++PN YF LDV T     +   
Sbjct: 134 PATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLG 193

Query: 183 LVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLD 242
           LVL K LDRE+      +LTA DGG                   + + TGT  L I VLD
Sbjct: 194 LVLRKLLDREETPELHLLLTATDGG-------------------KPELTGTVQLLITVLD 234

Query: 243 SNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFG 302
           +NDN P FD+ +YTV LPEN   GTLVI  NA+D DEG NG+++YSFSS +SP  +  F 
Sbjct: 235 NNDNAPVFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFH 294

Query: 303 LSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFST 362
           + P +G + V G +D+EES  +++ V+A D G   +  HC VLV V+D NDNAP+++ ++
Sbjct: 295 MDPLSGAITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTS 354

Query: 363 VKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLD 422
           +   + E A PGTV+ L SV DRD   NGQV C L   VPF+L S+FKNYY++V ++ LD
Sbjct: 355 LSLPIPEDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALD 414

Query: 423 REAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYI 482
           RE+  +Y L V ARD G P+L  + S+ V+V+DVNDNAP F+QP Y V+V ENN PG +I
Sbjct: 415 RESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHI 474

Query: 483 YAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQ 542
           + VSA D D   NA ++YS++E ++   ++ +YVS+++E+G +YAL+  D+E+L+   FQ
Sbjct: 475 FTVSAGDADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQ 534

Query: 543 VEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTR 602
           V ARDAG P  L  N T+ + ++D+NDNAPA++AP  G  G   RE++PRS   G+++ +
Sbjct: 535 VSARDAGVP-PLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAK 593

Query: 603 VAAVDADDGENARLTYSI--VRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEV 660
           V AVDAD G NA L+Y +  V       FR+   TGE+ T R +     P+  + L++ V
Sbjct: 594 VRAVDADSGYNAWLSYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPR--HRLLVLV 651

Query: 661 RDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSL-DLTLILI 719
           +DHG+P L++TAT++V LV+    P+    +  G            G ET L D+ + LI
Sbjct: 652 KDHGEPSLTATATVLVSLVESGQAPKASSRASLG----------IAGPETELVDVNVYLI 701

Query: 720 IALGSVSFIFLLAMIV-LAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARAR 778
           IA+ +VS + +L +++  A+RC         + L     +C    G    +   RQ    
Sbjct: 702 IAICAVSSLLVLTLLLYTALRCSAPSSEGACS-LVKPTLVCSSAVGSWSFSQQRRQRVCS 760

Query: 779 KKKLSKSDIMLVQSSNVPSNPA 800
            +   K+D+M   S ++P  P+
Sbjct: 761 GEGPPKTDLMAF-SPSLPQGPS 781


>gi|11128041 protocadherin gamma subfamily A, 10 isoform 1 precursor
           [Homo sapiens]
          Length = 936

 Score =  604 bits (1558), Expect = e-172
 Identities = 334/736 (45%), Positives = 465/736 (63%), Gaps = 38/736 (5%)

Query: 1   MIVLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSR 60
           +++ L F + W  E    Q+ Y++ EE E G+FVGNI++DLGL   +L+ RG + V   R
Sbjct: 18  VLLCLFFGIPW--EAGARQISYSIPEELEKGSFVGNISKDLGLAPRELAERGVRIVSRGR 75

Query: 61  TPYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPP 120
           T    LN  +G L    +IDRE++C QS  CV+   + +E+ ++LF +EIEV DINDN P
Sbjct: 76  TQLFSLNPRSGSLITAGRIDREELCAQSARCVVSFNILVEDRVKLFGIEIEVTDINDNAP 135

Query: 121 SFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRF 180
            F   +L V+I+E+   G RFPL  A DPDVG NSL+ Y+++PN +FSL VQ++ +G ++
Sbjct: 136 KFQAENLDVKINENVAAGMRFPLPEAIDPDVGVNSLQSYQLSPNKHFSLRVQSRANGVKY 195

Query: 181 AELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRV 240
            ELVLE  LDRE++A+H  VLTA DGG                      R+GT L+++ V
Sbjct: 196 PELVLEHSLDREEEAIHHLVLTASDGG-------------------DPLRSGTVLVSVTV 236

Query: 241 LDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRAREL 300
            D+NDN P F  P Y VS+PEN P GT ++ + ATD DEG NGEV YSF      +  + 
Sbjct: 237 FDANDNAPVFTLPEYRVSVPENLPVGTQLLTVTATDRDEGANGEVTYSFRKLPDTQLLK- 295

Query: 301 FGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISF 360
           F L+  TG +++S  LDYEE+  Y++ +QA+D G  A  A  KVL+ V D NDN+PE++ 
Sbjct: 296 FQLNKYTGEIKISENLDYEETGFYEIEIQAEDGG--AYLATAKVLITVEDVNDNSPELTI 353

Query: 361 STVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAP 420
           +++   V+E +  GTVVAL +V D DSE+NGQV C +L  +PF+L+ S  +YY +V    
Sbjct: 354 TSLFSPVTEDSPLGTVVALLNVHDLDSEQNGQVTCSILAYLPFKLEKSIDSYYRLVIHRA 413

Query: 421 LDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGA 480
           LDRE   SY +TV A D G P LST     +QV+D+NDN P FSQ  Y  Y+ ENN  GA
Sbjct: 414 LDREQVSSYNITVTATDGGSPPLSTEAHFMLQVADINDNPPTFSQVSYFTYIPENNARGA 473

Query: 481 YIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFS 540
            I++V+A D D   NAQ+ YS+ E  IQG+ + +Y+SINS+ G LYALRSFDYEQ  +  
Sbjct: 474 SIFSVTALDPDSKENAQIIYSLAEDTIQGVPLSSYISINSDTGVLYALRSFDYEQFHELQ 533

Query: 541 FQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLL 600
            QV A D+G P  L+ N ++++ ++DQNDNAP I+ P    +G+   E+ PRSAEPGYL+
Sbjct: 534 MQVTASDSGDP-PLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLV 592

Query: 601 TRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEV 660
           T+V AVD D G+NA L+Y +++ +E  LF +   TGE+RTAR +   RD  +   LV+ V
Sbjct: 593 TKVVAVDRDSGQNAWLSYRLLKASEPGLFAVGEHTGEVRTARAL-LDRDALK-QSLVVAV 650

Query: 661 RDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILII 720
           +DHGQPPLS+T TL V + D   +     GS        + P+ S   ETS DLTL L++
Sbjct: 651 QDHGQPPLSATVTLTVAVADSIPQVLADLGS-------FESPANS---ETS-DLTLYLVV 699

Query: 721 ALGSVSFIFLLAMIVL 736
           A+ +VS +FL  +IVL
Sbjct: 700 AVAAVSCVFLAFVIVL 715


>gi|14196448 protocadherin gamma subfamily A, 10 isoform 2 precursor
           [Homo sapiens]
          Length = 850

 Score =  604 bits (1558), Expect = e-172
 Identities = 334/736 (45%), Positives = 465/736 (63%), Gaps = 38/736 (5%)

Query: 1   MIVLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSR 60
           +++ L F + W  E    Q+ Y++ EE E G+FVGNI++DLGL   +L+ RG + V   R
Sbjct: 18  VLLCLFFGIPW--EAGARQISYSIPEELEKGSFVGNISKDLGLAPRELAERGVRIVSRGR 75

Query: 61  TPYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPP 120
           T    LN  +G L    +IDRE++C QS  CV+   + +E+ ++LF +EIEV DINDN P
Sbjct: 76  TQLFSLNPRSGSLITAGRIDREELCAQSARCVVSFNILVEDRVKLFGIEIEVTDINDNAP 135

Query: 121 SFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRF 180
            F   +L V+I+E+   G RFPL  A DPDVG NSL+ Y+++PN +FSL VQ++ +G ++
Sbjct: 136 KFQAENLDVKINENVAAGMRFPLPEAIDPDVGVNSLQSYQLSPNKHFSLRVQSRANGVKY 195

Query: 181 AELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRV 240
            ELVLE  LDRE++A+H  VLTA DGG                      R+GT L+++ V
Sbjct: 196 PELVLEHSLDREEEAIHHLVLTASDGG-------------------DPLRSGTVLVSVTV 236

Query: 241 LDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRAREL 300
            D+NDN P F  P Y VS+PEN P GT ++ + ATD DEG NGEV YSF      +  + 
Sbjct: 237 FDANDNAPVFTLPEYRVSVPENLPVGTQLLTVTATDRDEGANGEVTYSFRKLPDTQLLK- 295

Query: 301 FGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISF 360
           F L+  TG +++S  LDYEE+  Y++ +QA+D G  A  A  KVL+ V D NDN+PE++ 
Sbjct: 296 FQLNKYTGEIKISENLDYEETGFYEIEIQAEDGG--AYLATAKVLITVEDVNDNSPELTI 353

Query: 361 STVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAP 420
           +++   V+E +  GTVVAL +V D DSE+NGQV C +L  +PF+L+ S  +YY +V    
Sbjct: 354 TSLFSPVTEDSPLGTVVALLNVHDLDSEQNGQVTCSILAYLPFKLEKSIDSYYRLVIHRA 413

Query: 421 LDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGA 480
           LDRE   SY +TV A D G P LST     +QV+D+NDN P FSQ  Y  Y+ ENN  GA
Sbjct: 414 LDREQVSSYNITVTATDGGSPPLSTEAHFMLQVADINDNPPTFSQVSYFTYIPENNARGA 473

Query: 481 YIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFS 540
            I++V+A D D   NAQ+ YS+ E  IQG+ + +Y+SINS+ G LYALRSFDYEQ  +  
Sbjct: 474 SIFSVTALDPDSKENAQIIYSLAEDTIQGVPLSSYISINSDTGVLYALRSFDYEQFHELQ 533

Query: 541 FQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLL 600
            QV A D+G P  L+ N ++++ ++DQNDNAP I+ P    +G+   E+ PRSAEPGYL+
Sbjct: 534 MQVTASDSGDP-PLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLV 592

Query: 601 TRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEV 660
           T+V AVD D G+NA L+Y +++ +E  LF +   TGE+RTAR +   RD  +   LV+ V
Sbjct: 593 TKVVAVDRDSGQNAWLSYRLLKASEPGLFAVGEHTGEVRTARAL-LDRDALK-QSLVVAV 650

Query: 661 RDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILII 720
           +DHGQPPLS+T TL V + D   +     GS        + P+ S   ETS DLTL L++
Sbjct: 651 QDHGQPPLSATVTLTVAVADSIPQVLADLGS-------FESPANS---ETS-DLTLYLVV 699

Query: 721 ALGSVSFIFLLAMIVL 736
           A+ +VS +FL  +IVL
Sbjct: 700 AVAAVSCVFLAFVIVL 715


>gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo
           sapiens]
          Length = 814

 Score =  602 bits (1551), Expect = e-172
 Identities = 341/844 (40%), Positives = 487/844 (57%), Gaps = 82/844 (9%)

Query: 1   MIVLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSR 60
           +++LLL    W V     QLHY+V EE +HGTFVG IA+DLGL++ +L  R F+      
Sbjct: 14  LLLLLLLLAAWKVGS--GQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRH 71

Query: 61  TPYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPP 120
              L+++L+ G+L+VN +IDRE++C +S  C +HLEV ++ PL++F V++EV D+NDNPP
Sbjct: 72  RDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVNDNPP 131

Query: 121 SFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRF 180
            F   D  + +SES  P +RFPLE A D DVG NS+  Y ++ + YF LDV ++ D N+ 
Sbjct: 132 VFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDENKL 191

Query: 181 AELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRV 240
            ELVL K LDRE    H   LTA DGG                   + + TGT  L + V
Sbjct: 192 VELVLRKSLDREDAPAHHLFLTATDGG-------------------KPELTGTVQLLVTV 232

Query: 241 LDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRAREL 300
           LD NDN P F+Q  Y V + EN+  GT VI+LNA+DPDEG NG + YSF+S +     + 
Sbjct: 233 LDVNDNAPTFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDH 292

Query: 301 FGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISF 360
           F +   TG + + G LD+E+  +Y++ + A D G   +  HC VLVR+LD NDN PEI+ 
Sbjct: 293 FSIDRNTGEIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIAL 352

Query: 361 STVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAP 420
           +++   V E A  GTV+AL SV D DS  NGQV C L+  VPF+L S+FKNYY++V ++ 
Sbjct: 353 TSLSLPVREDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSA 412

Query: 421 LDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGA 480
           LDRE   +Y L V ARD G P+L  + S+ V+V+DVNDNAP F+QP Y V+V ENN PG 
Sbjct: 413 LDRERVSAYELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGC 472

Query: 481 YIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFS 540
           +I+ VSA D D   NA ++YS++E ++   S+ +Y+S+++E+G +YAL+  D+E+L+   
Sbjct: 473 HIFTVSARDADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQ 532

Query: 541 FQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLL 600
           FQV ARDAG P  L  N T+ + ++D+NDNAPA++ P  G  G  A +++PRS   G+++
Sbjct: 533 FQVSARDAGVP-PLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVV 591

Query: 601 TRVAAVDADDGENARLTYSI--VRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVI 658
            +V AVDAD G NA L+Y +     +    FR+   TGE+ T R +     P+  + L++
Sbjct: 592 AKVRAVDADSGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPR--HRLLV 649

Query: 659 EVRDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLIL 718
            V+DHG+P L++TAT++V LV+    P+       G  G              +D+ + L
Sbjct: 650 LVKDHGEPALTATATVLVSLVESGQAPKASSRQSAGVLGPE---------AALVDVNVYL 700

Query: 719 IIALGSVSFIFLLAMIVLAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARAR 778
           IIA+ +VS + +L ++             +YT L      C      GG        RA 
Sbjct: 701 IIAICAVSSLLVLTLL-------------LYTALR-----CSALPTEGG-------CRAG 735

Query: 779 KKKLSKSDIMLVQSSNVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKTDLMFLK 838
           K         LV SS V               GS  ++Q    +VC      KTDLM   
Sbjct: 736 KP-------TLVCSSAV---------------GSWSYSQQQPQRVCSGEGPPKTDLMAFS 773

Query: 839 PCSP 842
           PC P
Sbjct: 774 PCLP 777


>gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens]
          Length = 950

 Score =  602 bits (1551), Expect = e-172
 Identities = 341/844 (40%), Positives = 487/844 (57%), Gaps = 82/844 (9%)

Query: 1   MIVLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSR 60
           +++LLL    W V     QLHY+V EE +HGTFVG IA+DLGL++ +L  R F+      
Sbjct: 14  LLLLLLLLAAWKVGS--GQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRH 71

Query: 61  TPYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPP 120
              L+++L+ G+L+VN +IDRE++C +S  C +HLEV ++ PL++F V++EV D+NDNPP
Sbjct: 72  RDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVNDNPP 131

Query: 121 SFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRF 180
            F   D  + +SES  P +RFPLE A D DVG NS+  Y ++ + YF LDV ++ D N+ 
Sbjct: 132 VFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDENKL 191

Query: 181 AELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRV 240
            ELVL K LDRE    H   LTA DGG                   + + TGT  L + V
Sbjct: 192 VELVLRKSLDREDAPAHHLFLTATDGG-------------------KPELTGTVQLLVTV 232

Query: 241 LDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRAREL 300
           LD NDN P F+Q  Y V + EN+  GT VI+LNA+DPDEG NG + YSF+S +     + 
Sbjct: 233 LDVNDNAPTFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDH 292

Query: 301 FGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISF 360
           F +   TG + + G LD+E+  +Y++ + A D G   +  HC VLVR+LD NDN PEI+ 
Sbjct: 293 FSIDRNTGEIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIAL 352

Query: 361 STVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAP 420
           +++   V E A  GTV+AL SV D DS  NGQV C L+  VPF+L S+FKNYY++V ++ 
Sbjct: 353 TSLSLPVREDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSA 412

Query: 421 LDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGA 480
           LDRE   +Y L V ARD G P+L  + S+ V+V+DVNDNAP F+QP Y V+V ENN PG 
Sbjct: 413 LDRERVSAYELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGC 472

Query: 481 YIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFS 540
           +I+ VSA D D   NA ++YS++E ++   S+ +Y+S+++E+G +YAL+  D+E+L+   
Sbjct: 473 HIFTVSARDADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQ 532

Query: 541 FQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLL 600
           FQV ARDAG P  L  N T+ + ++D+NDNAPA++ P  G  G  A +++PRS   G+++
Sbjct: 533 FQVSARDAGVP-PLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVV 591

Query: 601 TRVAAVDADDGENARLTYSI--VRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVI 658
            +V AVDAD G NA L+Y +     +    FR+   TGE+ T R +     P+  + L++
Sbjct: 592 AKVRAVDADSGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPR--HRLLV 649

Query: 659 EVRDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLIL 718
            V+DHG+P L++TAT++V LV+    P+       G  G              +D+ + L
Sbjct: 650 LVKDHGEPALTATATVLVSLVESGQAPKASSRQSAGVLGPE---------AALVDVNVYL 700

Query: 719 IIALGSVSFIFLLAMIVLAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARAR 778
           IIA+ +VS + +L ++             +YT L      C      GG        RA 
Sbjct: 701 IIAICAVSSLLVLTLL-------------LYTALR-----CSALPTEGG-------CRAG 735

Query: 779 KKKLSKSDIMLVQSSNVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKTDLMFLK 838
           K         LV SS V               GS  ++Q    +VC      KTDLM   
Sbjct: 736 KP-------TLVCSSAV---------------GSWSYSQQQPQRVCSGEGPPKTDLMAFS 773

Query: 839 PCSP 842
           PC P
Sbjct: 774 PCLP 777


>gi|14196468 protocadherin gamma subfamily A, 4 isoform 2 precursor
           [Homo sapiens]
          Length = 820

 Score =  601 bits (1550), Expect = e-172
 Identities = 344/828 (41%), Positives = 488/828 (58%), Gaps = 77/828 (9%)

Query: 12  MVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRTPYLDLNLETG 71
           +VE    Q+ Y+V EEQE G+ VGNIA+DLGL   +L+ RG + V   RT    LN  +G
Sbjct: 23  LVEIRAEQILYSVFEEQEEGSVVGNIAKDLGLAPRELAERGVRIVSRGRTQLFALNPRSG 82

Query: 72  VLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPSFPEPDLTVEI 131
            L    +IDRE++C +SP+CV +LE+ LE+ +++ +VE+E++D+NDNPPSF      +++
Sbjct: 83  TLVTAGRIDREELCDRSPNCVTNLEILLEDTVKILRVEVEIIDVNDNPPSFGTEQREIKV 142

Query: 132 SESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAELVLEKPLDR 191
           +E+  PG RFPL  AFDPDVG NSL+ Y++  N YFSLDVQ+  DG ++ ELVLE+ LDR
Sbjct: 143 AENENPGARFPLPEAFDPDVGVNSLQGYQLNSNGYFSLDVQSGADGIKYPELVLERALDR 202

Query: 192 EQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLDSNDNVPAFD 251
           E++AVH  VLTA DGG                      R+GTA + I ++D+NDN P F 
Sbjct: 203 EEEAVHHLVLTAFDGG-------------------DPVRSGTARILIILVDTNDNAPVFT 243

Query: 252 QPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGLSPRTGRLE 311
           QP Y VS+ EN P GT ++ + ATDPDEG NG+V YSF   +  +  +LF L+  +G + 
Sbjct: 244 QPEYHVSVRENVPVGTRLLTVKATDPDEGANGDVTYSFRK-VRDKISQLFQLNSLSGDIT 302

Query: 312 VSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFSTVKEAVSEGA 371
           + G LDYE+S  Y + V+A D GP  + A  KVLV VLD NDNAPE++ +++  +V E +
Sbjct: 303 ILGGLDYEDSGFYDIDVEAHD-GP-GLRARSKVLVTVLDENDNAPEVTVTSLTSSVQESS 360

Query: 372 APGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLDREAGDSYTL 431
           +PGTV+ALF+V D DS  NG V C +  ++PF L+ ++ NYY ++T   LDRE    Y +
Sbjct: 361 SPGTVIALFNVHDSDSGGNGLVTCSIPDNLPFTLEKTYGNYYRLLTHRTLDREEVSEYNI 420

Query: 432 TVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRD 491
           TV A D+G P LST   I +QV D+NDN P F    Y  Y+ ENN  GA I +++A D D
Sbjct: 421 TVTATDQGTPPLSTETHISLQVMDINDNPPTFPHASYSAYIPENNPRGASILSMTAQDPD 480

Query: 492 EGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQVEARDAGSP 551
            G NA++ YS+ E   QG  + +YVSINS  G LYAL SFDYEQ +D    + A D+G P
Sbjct: 481 SGDNARITYSLAEDTFQGAPLSSYVSINSNTGILYALCSFDYEQFRDLQLLMTASDSGDP 540

Query: 552 QALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTRVAAVDADDG 611
             L+ N ++++ ++DQNDN P I+ P    +G+   E+ PRSA+ GYL+T+V AVD D G
Sbjct: 541 -PLSSNVSLSLFVLDQNDNVPEILYPTFPTDGSTGVELAPRSADSGYLVTKVVAVDRDSG 599

Query: 612 ENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSST 671
           +NA L+YS+++ +E  LF +   TGE+RTAR +   RD  +   LV+ V+DHGQPPLS+T
Sbjct: 600 QNAWLSYSLLKSSEPGLFAVGLHTGEVRTARAL-LDRDALK-QRLVVVVQDHGQPPLSAT 657

Query: 672 ATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILIIALGSVSFIFLL 731
            TL V + D   +     GS    +     P  SG       LTL L++A+ +VS +FL 
Sbjct: 658 VTLTVAVADSIPDVLADLGSLKPSAD----PDDSG-------LTLYLVVAVAAVSCVFLA 706

Query: 732 AMIVLAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARARKKKLSKSDIMLVQ 791
            + VL                                         + ++  KS ++  +
Sbjct: 707 FVTVLLA--------------------------------------LKLRRWHKSRLLHAE 728

Query: 792 SSNVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKTDLMFLKP 839
            S +   PA   +   G  G     Q Y ++V LT +S K+ L+F +P
Sbjct: 729 GSRLAGVPASHFV---GVDGVRAFLQTYSHEVSLTADSRKSHLIFSQP 773


>gi|11056026 protocadherin gamma subfamily A, 4 isoform 1 precursor
           [Homo sapiens]
          Length = 931

 Score =  601 bits (1550), Expect = e-172
 Identities = 344/828 (41%), Positives = 488/828 (58%), Gaps = 77/828 (9%)

Query: 12  MVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRTPYLDLNLETG 71
           +VE    Q+ Y+V EEQE G+ VGNIA+DLGL   +L+ RG + V   RT    LN  +G
Sbjct: 23  LVEIRAEQILYSVFEEQEEGSVVGNIAKDLGLAPRELAERGVRIVSRGRTQLFALNPRSG 82

Query: 72  VLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPSFPEPDLTVEI 131
            L    +IDRE++C +SP+CV +LE+ LE+ +++ +VE+E++D+NDNPPSF      +++
Sbjct: 83  TLVTAGRIDREELCDRSPNCVTNLEILLEDTVKILRVEVEIIDVNDNPPSFGTEQREIKV 142

Query: 132 SESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAELVLEKPLDR 191
           +E+  PG RFPL  AFDPDVG NSL+ Y++  N YFSLDVQ+  DG ++ ELVLE+ LDR
Sbjct: 143 AENENPGARFPLPEAFDPDVGVNSLQGYQLNSNGYFSLDVQSGADGIKYPELVLERALDR 202

Query: 192 EQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLDSNDNVPAFD 251
           E++AVH  VLTA DGG                      R+GTA + I ++D+NDN P F 
Sbjct: 203 EEEAVHHLVLTAFDGG-------------------DPVRSGTARILIILVDTNDNAPVFT 243

Query: 252 QPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGLSPRTGRLE 311
           QP Y VS+ EN P GT ++ + ATDPDEG NG+V YSF   +  +  +LF L+  +G + 
Sbjct: 244 QPEYHVSVRENVPVGTRLLTVKATDPDEGANGDVTYSFRK-VRDKISQLFQLNSLSGDIT 302

Query: 312 VSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFSTVKEAVSEGA 371
           + G LDYE+S  Y + V+A D GP  + A  KVLV VLD NDNAPE++ +++  +V E +
Sbjct: 303 ILGGLDYEDSGFYDIDVEAHD-GP-GLRARSKVLVTVLDENDNAPEVTVTSLTSSVQESS 360

Query: 372 APGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLDREAGDSYTL 431
           +PGTV+ALF+V D DS  NG V C +  ++PF L+ ++ NYY ++T   LDRE    Y +
Sbjct: 361 SPGTVIALFNVHDSDSGGNGLVTCSIPDNLPFTLEKTYGNYYRLLTHRTLDREEVSEYNI 420

Query: 432 TVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRD 491
           TV A D+G P LST   I +QV D+NDN P F    Y  Y+ ENN  GA I +++A D D
Sbjct: 421 TVTATDQGTPPLSTETHISLQVMDINDNPPTFPHASYSAYIPENNPRGASILSMTAQDPD 480

Query: 492 EGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQVEARDAGSP 551
            G NA++ YS+ E   QG  + +YVSINS  G LYAL SFDYEQ +D    + A D+G P
Sbjct: 481 SGDNARITYSLAEDTFQGAPLSSYVSINSNTGILYALCSFDYEQFRDLQLLMTASDSGDP 540

Query: 552 QALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTRVAAVDADDG 611
             L+ N ++++ ++DQNDN P I+ P    +G+   E+ PRSA+ GYL+T+V AVD D G
Sbjct: 541 -PLSSNVSLSLFVLDQNDNVPEILYPTFPTDGSTGVELAPRSADSGYLVTKVVAVDRDSG 599

Query: 612 ENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSST 671
           +NA L+YS+++ +E  LF +   TGE+RTAR +   RD  +   LV+ V+DHGQPPLS+T
Sbjct: 600 QNAWLSYSLLKSSEPGLFAVGLHTGEVRTARAL-LDRDALK-QRLVVVVQDHGQPPLSAT 657

Query: 672 ATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILIIALGSVSFIFLL 731
            TL V + D   +     GS    +     P  SG       LTL L++A+ +VS +FL 
Sbjct: 658 VTLTVAVADSIPDVLADLGSLKPSAD----PDDSG-------LTLYLVVAVAAVSCVFLA 706

Query: 732 AMIVLAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARARKKKLSKSDIMLVQ 791
            + VL                                         + ++  KS ++  +
Sbjct: 707 FVTVLLA--------------------------------------LKLRRWHKSRLLHAE 728

Query: 792 SSNVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKTDLMFLKP 839
            S +   PA   +   G  G     Q Y ++V LT +S K+ L+F +P
Sbjct: 729 GSRLAGVPASHFV---GVDGVRAFLQTYSHEVSLTADSRKSHLIFSQP 773


>gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo
           sapiens]
          Length = 798

 Score =  599 bits (1545), Expect = e-171
 Identities = 322/741 (43%), Positives = 466/741 (62%), Gaps = 34/741 (4%)

Query: 3   VLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRTP 62
           +LLL  LL   E    QLHY+V EE +HGTFVG IA+DLGL++ +L  R F+     R  
Sbjct: 14  LLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGG 73

Query: 63  YLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPSF 122
            L++NL+ G+L+VN +IDRE++C++S  C +HLEV ++ PL++F V++EV DINDNPP F
Sbjct: 74  LLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPVF 133

Query: 123 PEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAE 182
           P     + I+ES    +RFPLE A D D+G N+L  Y ++PN YFSL+     +  +   
Sbjct: 134 PATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDELVKGLG 193

Query: 183 LVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLD 242
           L+L K LDRE+      VLTA DGG                   + + TGT  L I VLD
Sbjct: 194 LILRKSLDREEAPEIFLVLTATDGG-------------------KPELTGTVQLLITVLD 234

Query: 243 SNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFG 302
           +NDN PAFD+ +Y V L EN P GTLVI+LNA+D DEG NG++VYSFS+ ISP  +  F 
Sbjct: 235 ANDNAPAFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFH 294

Query: 303 LSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFST 362
           + P TG++ V G +D+EES  Y++ V+  D G   +  HC+V+V V D NDN P++ F +
Sbjct: 295 IDPITGQIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKS 354

Query: 363 VKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLD 422
           +   + E A  GTV+AL SV+D+D   NG V C L   VPF+L S+FKNYY++V ++ LD
Sbjct: 355 LSLPIREDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALD 414

Query: 423 REAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYI 482
           RE+  +Y L V ARD G P+L  + S+ V+V+DVNDNAP F+QP Y V+V ENN PG +I
Sbjct: 415 RESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHI 474

Query: 483 YAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQ 542
           + VSA D D   NA ++YS++E ++   ++ +YVS+++E+G +YAL+  D+E+L+   FQ
Sbjct: 475 FTVSAWDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQ 534

Query: 543 VEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTR 602
           V ARDAG P  L  N T+ + ++D+NDNAPA++AP  G  G    E++P S   G+++ +
Sbjct: 535 VTARDAGVP-PLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAK 593

Query: 603 VAAVDADDGENARLTYSIV--RGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEV 660
           V AVDAD G NA L+Y +    G     FR+   TGE+ T R +     P+  + L++ V
Sbjct: 594 VRAVDADSGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPR--HRLLVLV 651

Query: 661 RDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILII 720
           +DHG+P L++TAT++V LV+    P+    +  G  G              +D+ + LII
Sbjct: 652 KDHGEPALTATATVLVSLVESGQAPKASSRALVGAVGP---------DAALVDVNVYLII 702

Query: 721 ALGSVSFIFLLAMIV-LAVRC 740
           A+ +VS + +L +++  A+RC
Sbjct: 703 AICAVSSLLVLTLLLYTALRC 723


>gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens]
          Length = 947

 Score =  599 bits (1545), Expect = e-171
 Identities = 322/741 (43%), Positives = 466/741 (62%), Gaps = 34/741 (4%)

Query: 3   VLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRTP 62
           +LLL  LL   E    QLHY+V EE +HGTFVG IA+DLGL++ +L  R F+     R  
Sbjct: 14  LLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGG 73

Query: 63  YLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPSF 122
            L++NL+ G+L+VN +IDRE++C++S  C +HLEV ++ PL++F V++EV DINDNPP F
Sbjct: 74  LLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPVF 133

Query: 123 PEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAE 182
           P     + I+ES    +RFPLE A D D+G N+L  Y ++PN YFSL+     +  +   
Sbjct: 134 PATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDELVKGLG 193

Query: 183 LVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLD 242
           L+L K LDRE+      VLTA DGG                   + + TGT  L I VLD
Sbjct: 194 LILRKSLDREEAPEIFLVLTATDGG-------------------KPELTGTVQLLITVLD 234

Query: 243 SNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFG 302
           +NDN PAFD+ +Y V L EN P GTLVI+LNA+D DEG NG++VYSFS+ ISP  +  F 
Sbjct: 235 ANDNAPAFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFH 294

Query: 303 LSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFST 362
           + P TG++ V G +D+EES  Y++ V+  D G   +  HC+V+V V D NDN P++ F +
Sbjct: 295 IDPITGQIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKS 354

Query: 363 VKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLD 422
           +   + E A  GTV+AL SV+D+D   NG V C L   VPF+L S+FKNYY++V ++ LD
Sbjct: 355 LSLPIREDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALD 414

Query: 423 REAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYI 482
           RE+  +Y L V ARD G P+L  + S+ V+V+DVNDNAP F+QP Y V+V ENN PG +I
Sbjct: 415 RESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHI 474

Query: 483 YAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQ 542
           + VSA D D   NA ++YS++E ++   ++ +YVS+++E+G +YAL+  D+E+L+   FQ
Sbjct: 475 FTVSAWDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQ 534

Query: 543 VEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTR 602
           V ARDAG P  L  N T+ + ++D+NDNAPA++AP  G  G    E++P S   G+++ +
Sbjct: 535 VTARDAGVP-PLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAK 593

Query: 603 VAAVDADDGENARLTYSIV--RGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEV 660
           V AVDAD G NA L+Y +    G     FR+   TGE+ T R +     P+  + L++ V
Sbjct: 594 VRAVDADSGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPR--HRLLVLV 651

Query: 661 RDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILII 720
           +DHG+P L++TAT++V LV+    P+    +  G  G              +D+ + LII
Sbjct: 652 KDHGEPALTATATVLVSLVESGQAPKASSRALVGAVGP---------DAALVDVNVYLII 702

Query: 721 ALGSVSFIFLLAMIV-LAVRC 740
           A+ +VS + +L +++  A+RC
Sbjct: 703 AICAVSSLLVLTLLLYTALRC 723


>gi|11056065 protocadherin gamma subfamily A, 6 isoform 1 precursor
           [Homo sapiens]
          Length = 932

 Score =  599 bits (1544), Expect = e-171
 Identities = 336/755 (44%), Positives = 467/755 (61%), Gaps = 57/755 (7%)

Query: 1   MIVLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSR 60
           +++L L   LW      +Q+ Y++ EE E G+FVGNI +DLGL+  +L+  G + V   R
Sbjct: 14  VLLLTLLGTLWGAAA--AQIRYSIPEELEKGSFVGNIVKDLGLEPQELAEHGVRIVSRGR 71

Query: 61  TPYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPP 120
                LN   G L    +IDRE++C QSP C++   + +E+ L L+ VE+E++DINDN P
Sbjct: 72  MQLFSLNPRNGSLVTAGRIDREELCAQSPRCLVSFNILVEDKLNLYPVEVEIVDINDNTP 131

Query: 121 SFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRF 180
            F + +L V+I E+A P +RFPL   +DPDVG NSL+ ++++ NS+FS+DVQ++  G ++
Sbjct: 132 RFLKEELEVKILENAAPSSRFPLMEVYDPDVGMNSLQGFKLSGNSHFSVDVQSEAHGPKY 191

Query: 181 AELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRV 240
            ELVLE  LDRE +AV+R VLTA+DGG                      R+  A + + V
Sbjct: 192 PELVLEGTLDREGEAVYRLVLTAMDGG-------------------DPVRSSVAQILVTV 232

Query: 241 LDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRAREL 300
           LD NDN P F QPVY VS+PEN P GT V+ + ATD DEG +GEV YSF   I+ +  ++
Sbjct: 233 LDVNDNTPMFTQPVYRVSVPENLPVGTPVLAVTATDQDEGVHGEVTYSFVK-ITEKISQI 291

Query: 301 FGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISF 360
           F L+  TG +  S  LDYE+S  Y++ V+A+D GP  +    KVL+ +LD NDN PE+  
Sbjct: 292 FCLNVLTGEISTSANLDYEDSSFYELGVEARD-GPG-LRDRAKVLITILDVNDNVPEVVV 349

Query: 361 STVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAP 420
           ++    ++E A PGTV+ALF V DRDS  NG V C +   +PF L+ S  NYY +VT A 
Sbjct: 350 TSGSRTIAESAPPGTVIALFQVFDRDSGLNGLVTCSIPRSLPFELEKSVGNYYRLVTNAA 409

Query: 421 LDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGA 480
           LDRE    Y +TV A D+G P LST   I + V+D NDN P F    Y VYV ENN  GA
Sbjct: 410 LDREEVFLYNITVTATDKGTPPLSTETIISLNVADTNDNPPTFPHSSYSVYVLENNPRGA 469

Query: 481 YIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFS 540
            I++V+A D D   NAQ++YS+ E  +QG  + +YVSINS+ G LYALRSFDYEQL+D  
Sbjct: 470 SIFSVNALDPDVDQNAQVSYSLAEDTLQGAPLSSYVSINSDTGILYALRSFDYEQLRDLQ 529

Query: 541 FQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLL 600
             V A D+G P  L+ N ++++ ++DQNDNAP I+ P    +G+   E+ PRSAEPGYL+
Sbjct: 530 LWVTASDSGDP-PLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLV 588

Query: 601 TRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEV 660
           T+V AVD D G+NA L+Y +++ +E  LF +   TGE+RTAR +   RD  +   LV+ V
Sbjct: 589 TKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARAL-LDRDALK-QSLVVAV 646

Query: 661 RDHGQPPLSSTATLVVQLVD---------GAVEPQGGGGSGGGGSGEHQRPSRSGGGETS 711
           +DHGQPPLS+T TL V + D         G++EP               +P+ S      
Sbjct: 647 QDHGQPPLSATVTLTVAVADRIPDILADLGSLEPSA-------------KPNDS------ 687

Query: 712 LDLTLILIIALGSVSFIFLLAMIV-LAVRCQKEKK 745
            DLTL L++A+ +VS +FL  +IV LA+R Q+  K
Sbjct: 688 -DLTLYLVVAVAAVSCVFLAFVIVLLALRLQRWHK 721


>gi|14196474 protocadherin gamma subfamily A, 6 isoform 2 precursor
           [Homo sapiens]
          Length = 818

 Score =  599 bits (1544), Expect = e-171
 Identities = 336/755 (44%), Positives = 467/755 (61%), Gaps = 57/755 (7%)

Query: 1   MIVLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSR 60
           +++L L   LW      +Q+ Y++ EE E G+FVGNI +DLGL+  +L+  G + V   R
Sbjct: 14  VLLLTLLGTLWGAAA--AQIRYSIPEELEKGSFVGNIVKDLGLEPQELAEHGVRIVSRGR 71

Query: 61  TPYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPP 120
                LN   G L    +IDRE++C QSP C++   + +E+ L L+ VE+E++DINDN P
Sbjct: 72  MQLFSLNPRNGSLVTAGRIDREELCAQSPRCLVSFNILVEDKLNLYPVEVEIVDINDNTP 131

Query: 121 SFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRF 180
            F + +L V+I E+A P +RFPL   +DPDVG NSL+ ++++ NS+FS+DVQ++  G ++
Sbjct: 132 RFLKEELEVKILENAAPSSRFPLMEVYDPDVGMNSLQGFKLSGNSHFSVDVQSEAHGPKY 191

Query: 181 AELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRV 240
            ELVLE  LDRE +AV+R VLTA+DGG                      R+  A + + V
Sbjct: 192 PELVLEGTLDREGEAVYRLVLTAMDGG-------------------DPVRSSVAQILVTV 232

Query: 241 LDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRAREL 300
           LD NDN P F QPVY VS+PEN P GT V+ + ATD DEG +GEV YSF   I+ +  ++
Sbjct: 233 LDVNDNTPMFTQPVYRVSVPENLPVGTPVLAVTATDQDEGVHGEVTYSFVK-ITEKISQI 291

Query: 301 FGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISF 360
           F L+  TG +  S  LDYE+S  Y++ V+A+D GP  +    KVL+ +LD NDN PE+  
Sbjct: 292 FCLNVLTGEISTSANLDYEDSSFYELGVEARD-GPG-LRDRAKVLITILDVNDNVPEVVV 349

Query: 361 STVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAP 420
           ++    ++E A PGTV+ALF V DRDS  NG V C +   +PF L+ S  NYY +VT A 
Sbjct: 350 TSGSRTIAESAPPGTVIALFQVFDRDSGLNGLVTCSIPRSLPFELEKSVGNYYRLVTNAA 409

Query: 421 LDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGA 480
           LDRE    Y +TV A D+G P LST   I + V+D NDN P F    Y VYV ENN  GA
Sbjct: 410 LDREEVFLYNITVTATDKGTPPLSTETIISLNVADTNDNPPTFPHSSYSVYVLENNPRGA 469

Query: 481 YIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFS 540
            I++V+A D D   NAQ++YS+ E  +QG  + +YVSINS+ G LYALRSFDYEQL+D  
Sbjct: 470 SIFSVNALDPDVDQNAQVSYSLAEDTLQGAPLSSYVSINSDTGILYALRSFDYEQLRDLQ 529

Query: 541 FQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLL 600
             V A D+G P  L+ N ++++ ++DQNDNAP I+ P    +G+   E+ PRSAEPGYL+
Sbjct: 530 LWVTASDSGDP-PLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLV 588

Query: 601 TRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEV 660
           T+V AVD D G+NA L+Y +++ +E  LF +   TGE+RTAR +   RD  +   LV+ V
Sbjct: 589 TKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARAL-LDRDALK-QSLVVAV 646

Query: 661 RDHGQPPLSSTATLVVQLVD---------GAVEPQGGGGSGGGGSGEHQRPSRSGGGETS 711
           +DHGQPPLS+T TL V + D         G++EP               +P+ S      
Sbjct: 647 QDHGQPPLSATVTLTVAVADRIPDILADLGSLEPSA-------------KPNDS------ 687

Query: 712 LDLTLILIIALGSVSFIFLLAMIV-LAVRCQKEKK 745
            DLTL L++A+ +VS +FL  +IV LA+R Q+  K
Sbjct: 688 -DLTLYLVVAVAAVSCVFLAFVIVLLALRLQRWHK 721


>gi|11056032 protocadherin gamma subfamily A, 1 isoform 1 precursor
           [Homo sapiens]
          Length = 931

 Score =  598 bits (1542), Expect = e-171
 Identities = 344/847 (40%), Positives = 491/847 (57%), Gaps = 95/847 (11%)

Query: 2   IVLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRT 61
           ++LL  +L  ++E     +HY+V EE + G+FVGNIA+DLGL   +L+  G + V   R 
Sbjct: 13  LMLLCLSLELLLEAGAGNIHYSVPEETDKGSFVGNIAKDLGLQPQELADGGVRIVSRGRM 72

Query: 62  PYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPS 121
           P   LN  +G L    +IDRE++C QS  C++   + +E+ ++LF VE+E++DINDN P 
Sbjct: 73  PLFALNPRSGSLITARRIDREELCAQSMPCLVSFNILVEDKMKLFPVEVEIIDINDNTPQ 132

Query: 122 FPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFA 181
           F   +L  +++E  TPGTR  L    D DVG NSL+ Y+++ N +FSLDVQ   DG +  
Sbjct: 133 FQLEELEFKMNEITTPGTRVSLPFGQDLDVGMNSLQSYQLSSNPHFSLDVQQGADGPQHP 192

Query: 182 ELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVL 241
           E+VL+ PLDRE++AVH  +LTA DGG                   +  R+GT  + I+V+
Sbjct: 193 EMVLQSPLDREEEAVHHLILTASDGG-------------------EPVRSGTLRIYIQVV 233

Query: 242 DSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELF 301
           D+NDN PAF Q  Y +++PEN P GT ++ +NATDPDEG NGEV YSF + +  R  ++F
Sbjct: 234 DANDNPPAFTQAQYHINVPENVPLGTQLLMVNATDPDEGANGEVTYSFHN-VDHRVAQIF 292

Query: 302 GLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFS 361
            L   TG +     LD+EE  +Y + VQA+D     + A  KVL++VLD NDNAPE++ +
Sbjct: 293 RLDSYTGEISNKEPLDFEEYKMYSMEVQAQDGA--GLMAKVKVLIKVLDVNDNAPEVTIT 350

Query: 362 TVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPL 421
           +V  AV E   PGT++AL SV D+DS +NG   C + G++PF+L+    NYY +VTE  L
Sbjct: 351 SVTTAVPENFPPGTIIALISVHDQDSGDNGYTTCFIPGNLPFKLEKLVDNYYRLVTERTL 410

Query: 422 DREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAY 481
           DRE    Y +T+ A D+G PALST   I + V+D+NDN+P F Q  Y  Y+ ENN  GA 
Sbjct: 411 DRELISGYNITITAIDQGTPALSTETHISLLVTDINDNSPVFHQDSYSAYIPENNPRGAS 470

Query: 482 IYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSF 541
           I++V A D D   NAQ+ YS++E  IQG  +  Y+SINS+ G LYALRSFDYEQ +D   
Sbjct: 471 IFSVRAHDLDSNENAQITYSLIEDTIQGAPLSAYLSINSDTGVLYALRSFDYEQFRDMQL 530

Query: 542 QVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLT 601
           +V ARD+G P  L+ N ++++ ++DQNDNAP I+ P    +G+   E+ P SAEPGYL+T
Sbjct: 531 KVMARDSGDP-PLSSNVSLSLFLLDQNDNAPEILYPALPTDGSTGVELAPLSAEPGYLVT 589

Query: 602 RVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVR 661
           +V AVD D G+NA L+Y +++ +E  LF +   TGE+RTAR +   RD  +   LV+ V+
Sbjct: 590 KVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARAL-LDRDALK-QSLVVAVQ 647

Query: 662 DHGQPPLSSTATLVVQLVD---------GAVEPQGGGGSGGGGSGEHQRPSRSGGGETSL 712
           DHGQPPLS+T TL V + D         G++EP               +P+ S       
Sbjct: 648 DHGQPPLSATVTLTVAVADRISDILADLGSLEPSA-------------KPNDS------- 687

Query: 713 DLTLILIIALGSVSFIFLLAMIVLAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCG 772
           DLTL L++A  +VS +FL  +IVL                                    
Sbjct: 688 DLTLYLVVAAAAVSCVFLAFVIVLLAH--------------------------------- 714

Query: 773 RQARARKKKLSKSDIMLVQSSNVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKT 832
                R ++  KS ++      + S P    +   G  G     Q Y ++V LT +S K+
Sbjct: 715 -----RLRRWHKSRLLQASGGGLASMPGSHFV---GVDGVRAFLQTYSHEVSLTADSRKS 766

Query: 833 DLMFLKP 839
            L+F +P
Sbjct: 767 HLIFPQP 773


>gi|14196459 protocadherin gamma subfamily A, 1 isoform 2 precursor
           [Homo sapiens]
          Length = 823

 Score =  598 bits (1542), Expect = e-171
 Identities = 344/847 (40%), Positives = 491/847 (57%), Gaps = 95/847 (11%)

Query: 2   IVLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRT 61
           ++LL  +L  ++E     +HY+V EE + G+FVGNIA+DLGL   +L+  G + V   R 
Sbjct: 13  LMLLCLSLELLLEAGAGNIHYSVPEETDKGSFVGNIAKDLGLQPQELADGGVRIVSRGRM 72

Query: 62  PYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPS 121
           P   LN  +G L    +IDRE++C QS  C++   + +E+ ++LF VE+E++DINDN P 
Sbjct: 73  PLFALNPRSGSLITARRIDREELCAQSMPCLVSFNILVEDKMKLFPVEVEIIDINDNTPQ 132

Query: 122 FPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFA 181
           F   +L  +++E  TPGTR  L    D DVG NSL+ Y+++ N +FSLDVQ   DG +  
Sbjct: 133 FQLEELEFKMNEITTPGTRVSLPFGQDLDVGMNSLQSYQLSSNPHFSLDVQQGADGPQHP 192

Query: 182 ELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVL 241
           E+VL+ PLDRE++AVH  +LTA DGG                   +  R+GT  + I+V+
Sbjct: 193 EMVLQSPLDREEEAVHHLILTASDGG-------------------EPVRSGTLRIYIQVV 233

Query: 242 DSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELF 301
           D+NDN PAF Q  Y +++PEN P GT ++ +NATDPDEG NGEV YSF + +  R  ++F
Sbjct: 234 DANDNPPAFTQAQYHINVPENVPLGTQLLMVNATDPDEGANGEVTYSFHN-VDHRVAQIF 292

Query: 302 GLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFS 361
            L   TG +     LD+EE  +Y + VQA+D     + A  KVL++VLD NDNAPE++ +
Sbjct: 293 RLDSYTGEISNKEPLDFEEYKMYSMEVQAQDGA--GLMAKVKVLIKVLDVNDNAPEVTIT 350

Query: 362 TVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPL 421
           +V  AV E   PGT++AL SV D+DS +NG   C + G++PF+L+    NYY +VTE  L
Sbjct: 351 SVTTAVPENFPPGTIIALISVHDQDSGDNGYTTCFIPGNLPFKLEKLVDNYYRLVTERTL 410

Query: 422 DREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAY 481
           DRE    Y +T+ A D+G PALST   I + V+D+NDN+P F Q  Y  Y+ ENN  GA 
Sbjct: 411 DRELISGYNITITAIDQGTPALSTETHISLLVTDINDNSPVFHQDSYSAYIPENNPRGAS 470

Query: 482 IYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSF 541
           I++V A D D   NAQ+ YS++E  IQG  +  Y+SINS+ G LYALRSFDYEQ +D   
Sbjct: 471 IFSVRAHDLDSNENAQITYSLIEDTIQGAPLSAYLSINSDTGVLYALRSFDYEQFRDMQL 530

Query: 542 QVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLT 601
           +V ARD+G P  L+ N ++++ ++DQNDNAP I+ P    +G+   E+ P SAEPGYL+T
Sbjct: 531 KVMARDSGDP-PLSSNVSLSLFLLDQNDNAPEILYPALPTDGSTGVELAPLSAEPGYLVT 589

Query: 602 RVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVR 661
           +V AVD D G+NA L+Y +++ +E  LF +   TGE+RTAR +   RD  +   LV+ V+
Sbjct: 590 KVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARAL-LDRDALK-QSLVVAVQ 647

Query: 662 DHGQPPLSSTATLVVQLVD---------GAVEPQGGGGSGGGGSGEHQRPSRSGGGETSL 712
           DHGQPPLS+T TL V + D         G++EP               +P+ S       
Sbjct: 648 DHGQPPLSATVTLTVAVADRISDILADLGSLEPSA-------------KPNDS------- 687

Query: 713 DLTLILIIALGSVSFIFLLAMIVLAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCG 772
           DLTL L++A  +VS +FL  +IVL                                    
Sbjct: 688 DLTLYLVVAAAAVSCVFLAFVIVLLAH--------------------------------- 714

Query: 773 RQARARKKKLSKSDIMLVQSSNVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKT 832
                R ++  KS ++      + S P    +   G  G     Q Y ++V LT +S K+
Sbjct: 715 -----RLRRWHKSRLLQASGGGLASMPGSHFV---GVDGVRAFLQTYSHEVSLTADSRKS 766

Query: 833 DLMFLKP 839
            L+F +P
Sbjct: 767 HLIFPQP 773


>gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo
           sapiens]
          Length = 807

 Score =  597 bits (1539), Expect = e-170
 Identities = 328/797 (41%), Positives = 474/797 (59%), Gaps = 42/797 (5%)

Query: 9   LLWMV-----EGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRTPY 63
           LLW++     E    QLHY+V EE +HGTFVG IA+DLGL++ +L  R F+         
Sbjct: 15  LLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRHGDL 74

Query: 64  LDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPSFP 123
           L++NL+ G+L+VN +IDRE++C +S  C +HLEV ++ PL++F VE++V DINDNPP FP
Sbjct: 75  LEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDINDNPPIFP 134

Query: 124 EPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAEL 183
           E    + I+ES  P TRFPL+ A D D+G NS   Y + PN YF+LD Q   +      L
Sbjct: 135 ESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSLEQMSSLSL 194

Query: 184 VLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLDS 243
           VL K LDRE+   H  +LTA DGG                   + + TGT  L I +LD 
Sbjct: 195 VLRKTLDREEIQEHSLLLTASDGG-------------------KPELTGTVQLLITILDV 235

Query: 244 NDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGL 303
           NDN P F Q VY V++ EN+  GTLVI+LNATDPD+G NG++VYSF   + P     F +
Sbjct: 236 NDNAPEFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTI 295

Query: 304 SPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFSTV 363
           +P  G +   G+LD+EE  +Y++ V+A D G   +  HC +LV VLD NDNAPE++ +++
Sbjct: 296 NPNNGEIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSL 355

Query: 364 KEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLDR 423
              + E   P  ++AL SV+DRDS  NGQV C L   VPF+L S++KNYY++V ++ LDR
Sbjct: 356 SLPIREDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDR 415

Query: 424 EAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIY 483
           E+  +Y L V ARD G P+L  + S+ V V+DVNDNAP F+QP Y V+V ENN PG +I+
Sbjct: 416 ESVSAYELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIF 475

Query: 484 AVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQV 543
            VSA D D   NA ++YS++E ++   ++ +YVS+++E+G +YAL+  D+E+L+   FQV
Sbjct: 476 TVSAQDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQV 535

Query: 544 EARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTRV 603
            ARD+G P  L  N T+ + ++D+NDNAPA++ P  G  G    E++PRS   G+++ +V
Sbjct: 536 SARDSGVP-PLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKV 594

Query: 604 AAVDADDGENARLTY--SIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVR 661
            AVDAD G NA L+Y   +        FR+   TGE+ T R +     P   + L++ V+
Sbjct: 595 RAVDADSGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPH--HRLLVLVK 652

Query: 662 DHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILIIA 721
           DHG+P L++TAT+++ LV+    PQ    +  G  G              +D+ + LIIA
Sbjct: 653 DHGEPALTATATVLLSLVESGQAPQASSRASAGAVGPE---------AALVDVNVYLIIA 703

Query: 722 LGSVSFIFLLAMIV-LAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQAR-ARK 779
           + +VS + +L +++  A+RC          C      L C    G  S    R+ R    
Sbjct: 704 ICAVSSLLVLTLLLYTALRCSAPPTEG--ACAPGKPTLVCSSAAGSWSYSQQRRPRVCSG 761

Query: 780 KKLSKSDIMLVQSSNVP 796
           +   K+D+M    S  P
Sbjct: 762 EGPHKTDLMAFSPSLPP 778


>gi|9256580 protocadherin alpha 13 isoform 1 precursor [Homo
           sapiens]
          Length = 950

 Score =  597 bits (1539), Expect = e-170
 Identities = 328/797 (41%), Positives = 474/797 (59%), Gaps = 42/797 (5%)

Query: 9   LLWMV-----EGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRTPY 63
           LLW++     E    QLHY+V EE +HGTFVG IA+DLGL++ +L  R F+         
Sbjct: 15  LLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRHGDL 74

Query: 64  LDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPSFP 123
           L++NL+ G+L+VN +IDRE++C +S  C +HLEV ++ PL++F VE++V DINDNPP FP
Sbjct: 75  LEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDINDNPPIFP 134

Query: 124 EPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAEL 183
           E    + I+ES  P TRFPL+ A D D+G NS   Y + PN YF+LD Q   +      L
Sbjct: 135 ESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSLEQMSSLSL 194

Query: 184 VLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLDS 243
           VL K LDRE+   H  +LTA DGG                   + + TGT  L I +LD 
Sbjct: 195 VLRKTLDREEIQEHSLLLTASDGG-------------------KPELTGTVQLLITILDV 235

Query: 244 NDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGL 303
           NDN P F Q VY V++ EN+  GTLVI+LNATDPD+G NG++VYSF   + P     F +
Sbjct: 236 NDNAPEFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTI 295

Query: 304 SPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFSTV 363
           +P  G +   G+LD+EE  +Y++ V+A D G   +  HC +LV VLD NDNAPE++ +++
Sbjct: 296 NPNNGEIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSL 355

Query: 364 KEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLDR 423
              + E   P  ++AL SV+DRDS  NGQV C L   VPF+L S++KNYY++V ++ LDR
Sbjct: 356 SLPIREDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDR 415

Query: 424 EAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIY 483
           E+  +Y L V ARD G P+L  + S+ V V+DVNDNAP F+QP Y V+V ENN PG +I+
Sbjct: 416 ESVSAYELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIF 475

Query: 484 AVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQV 543
            VSA D D   NA ++YS++E ++   ++ +YVS+++E+G +YAL+  D+E+L+   FQV
Sbjct: 476 TVSAQDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQV 535

Query: 544 EARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTRV 603
            ARD+G P  L  N T+ + ++D+NDNAPA++ P  G  G    E++PRS   G+++ +V
Sbjct: 536 SARDSGVP-PLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKV 594

Query: 604 AAVDADDGENARLTY--SIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVR 661
            AVDAD G NA L+Y   +        FR+   TGE+ T R +     P   + L++ V+
Sbjct: 595 RAVDADSGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPH--HRLLVLVK 652

Query: 662 DHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILIIA 721
           DHG+P L++TAT+++ LV+    PQ    +  G  G              +D+ + LIIA
Sbjct: 653 DHGEPALTATATVLLSLVESGQAPQASSRASAGAVGPE---------AALVDVNVYLIIA 703

Query: 722 LGSVSFIFLLAMIV-LAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQAR-ARK 779
           + +VS + +L +++  A+RC          C      L C    G  S    R+ R    
Sbjct: 704 ICAVSSLLVLTLLLYTALRCSAPPTEG--ACAPGKPTLVCSSAAGSWSYSQQRRPRVCSG 761

Query: 780 KKLSKSDIMLVQSSNVP 796
           +   K+D+M    S  P
Sbjct: 762 EGPHKTDLMAFSPSLPP 778


>gi|9256610 protocadherin beta 15 precursor [Homo sapiens]
          Length = 787

 Score =  597 bits (1538), Expect = e-170
 Identities = 348/844 (41%), Positives = 507/844 (60%), Gaps = 87/844 (10%)

Query: 3   VLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRTP 62
           VL+L  LL +    +    Y+V EE E G+FV N+A DLGL + +L+ RG + V      
Sbjct: 14  VLILLLLLEVTLAGWEPRRYSVMEETERGSFVANLANDLGLGVGELAERGARVVSEDNEQ 73

Query: 63  YLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPSF 122
            L L+L+TG L +NEK+DRE++C  +  C++H +V L+ PLE+F+ E+ V DIND+ P F
Sbjct: 74  GLQLDLQTGQLILNEKLDREKLCGPTEPCIMHFQVLLKKPLEVFRAELLVTDINDHSPEF 133

Query: 123 PEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAE 182
           PE ++T++I E+++ GT FPL+ A D DVG+N++++Y I+PNS+F +  +T+GDG ++ E
Sbjct: 134 PEREMTLKIPETSSLGTVFPLKKARDLDVGSNNVQNYNISPNSHFHVSTRTRGDGRKYPE 193

Query: 183 LVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLD 242
           LVL+  LDRE+QA  R  LTAVDGG                 PP   R+GT  + I VLD
Sbjct: 194 LVLDTELDREEQAELRLTLTAVDGGS----------------PP---RSGTVQILILVLD 234

Query: 243 SNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFG 302
           +NDN P F Q +Y V +PENSP G+LV++++A D D G NGE+ YS   + S    + F 
Sbjct: 235 ANDNAPEFVQALYEVQVPENSPVGSLVVKVSARDLDTGTNGEISYSL-YYSSQEIDKPFE 293

Query: 303 LSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFST 362
           LS  +G + +  +LD+E    Y + ++A D G   +   C V V+VLD NDN PE+S S+
Sbjct: 294 LSSLSGEIRLIKKLDFETMSSYDLDIEASDGG--GLSGKCSVSVKVLDVNDNFPELSISS 351

Query: 363 VKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLD 422
           +   + E  +P T VALF + DRDS ENG++ C +  DVPF+LK S +N+Y +VTE  LD
Sbjct: 352 LTSPIPEN-SPETEVALFRIRDRDSGENGKMICSIQDDVPFKLKPSVENFYRLVTEGALD 410

Query: 423 REAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYI 482
           RE    Y +T+   D G P L T +SI V VSDVNDNAP F+Q  Y ++V ENN P  +I
Sbjct: 411 RETRAEYNITITITDLGTPRLKTEQSITVLVSDVNDNAPAFTQTSYTLFVRENNSPALHI 470

Query: 483 YAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQ 542
            +VSATDRD G NAQ+ YS+L  +   + + + VSIN++NG+L+AL+S DYE L+ F F+
Sbjct: 471 GSVSATDRDSGTNAQVTYSLLPPRDPHLPLTSLVSINTDNGHLFALQSLDYEALQAFEFR 530

Query: 543 VEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGT-PAREVLPRSAEPGYLLT 601
           V A D G P AL+  A V +L++D NDN+P ++ PL  +NG+ P  E++PR+AEPGYL+T
Sbjct: 531 VGATDRGFP-ALSSEALVRVLVLDANDNSPFVLYPL--QNGSAPCTELVPRAAEPGYLVT 587

Query: 602 RVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVR 661
           +V AVD D G+NA L+Y +++  E  LF +    GE+RTAR + ++RD  + + LV+ V+
Sbjct: 588 KVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLL-SERDVAK-HRLVVLVK 645

Query: 662 DHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILIIA 721
           D+G+PP S+TATL V LVDG  +P                P  +     +  LT+ L++A
Sbjct: 646 DNGEPPRSATATLQVLLVDGFSQPY------------LPLPEAAPAQAQADSLTVYLVVA 693

Query: 722 LGSVSFIFLLAM-IVLAVR-CQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARARK 779
           L SVS +FL ++ + +AVR C++ +  ++  C                            
Sbjct: 694 LASVSSLFLFSVFLFVAVRLCRRSRAASVGRC---------------------------- 725

Query: 780 KKLSKSDIMLVQSSNVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKTDLMFLKP 839
                         +VP  P    + +  G G+   +Q+Y Y+VCLT  S   D  FLKP
Sbjct: 726 --------------SVPEGPFPGHLVDVSGTGT--LSQSYQYEVCLTGGSESNDFKFLKP 769

Query: 840 CSPS 843
             P+
Sbjct: 770 IFPN 773


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.134    0.393 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,262,034
Number of Sequences: 37866
Number of extensions: 1916899
Number of successful extensions: 25488
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 372
Number of HSP's successfully gapped in prelim test: 67
Number of HSP's that attempted gapping in prelim test: 10817
Number of HSP's gapped (non-prelim): 5857
length of query: 896
length of database: 18,247,518
effective HSP length: 111
effective length of query: 785
effective length of database: 14,044,392
effective search space: 11024847720
effective search space used: 11024847720
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.