Guide to the Human Genome
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Search of human proteins with 109633019

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|109633019 Wolf-Hirschhorn syndrome candidate 1 protein
isoform 1 [Homo sapiens]
         (1365 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|19913358 Wolf-Hirschhorn syndrome candidate 1 protein isoform...  2848   0.0  
gi|19913350 Wolf-Hirschhorn syndrome candidate 1 protein isoform...  2848   0.0  
gi|19913348 Wolf-Hirschhorn syndrome candidate 1 protein isoform...  2848   0.0  
gi|109633019 Wolf-Hirschhorn syndrome candidate 1 protein isofor...  2848   0.0  
gi|6594683 Wolf-Hirschhorn syndrome candidate 1 protein isoform ...  1243   0.0  
gi|19913356 Wolf-Hirschhorn syndrome candidate 1 protein isoform...  1243   0.0  
gi|13699811 WHSC1L1 protein isoform long [Homo sapiens]              1177   0.0  
gi|27477095 nuclear receptor binding SET domain protein 1 isofor...  1051   0.0  
gi|19923586 nuclear receptor binding SET domain protein 1 isofor...  1051   0.0  
gi|197313748 SET domain containing 2 [Homo sapiens]                   203   1e-51
gi|13699813 WHSC1L1 protein isoform short [Homo sapiens]              202   2e-51
gi|110349788 absent, small, or homeotic 1-like [Homo sapiens]         185   3e-46
gi|13375930 suppressor of variegation 3-9 homolog 2 [Homo sapiens]    101   6e-21
gi|19923202 enhancer of zeste homolog 1 [Homo sapiens]                 97   1e-19
gi|23510384 enhancer of zeste 2 isoform b [Homo sapiens]               95   5e-19
gi|21361095 enhancer of zeste 2 isoform a [Homo sapiens]               95   5e-19
gi|210032580 SET domain containing 1B [Homo sapiens]                   91   8e-18
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [...    89   3e-17
gi|4507321 suppressor of variegation 3-9 homolog 1 [Homo sapiens]      89   4e-17
gi|194306650 SET domain and mariner transposase fusion [Homo sap...    83   2e-15
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    83   2e-15
gi|55741677 SET domain containing 1A [Homo sapiens]                    82   3e-15
gi|156142199 euchromatic histone-lysine N-methyltransferase 2 is...    79   2e-14
gi|156142197 euchromatic histone-lysine N-methyltransferase 2 is...    79   2e-14
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa...    79   3e-14
gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo s...    79   4e-14
gi|224465233 euchromatic histone-lysine N-methyltransferase 1 is...    78   5e-14
gi|4504191 mutS homolog 6 [Homo sapiens]                               72   4e-12
gi|94721344 zinc finger, CW type with PWWP domain 1 [Homo sapiens]     65   3e-10
gi|24308089 chromodomain helicase DNA binding protein 5 [Homo sa...    62   3e-09

>gi|19913358 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
            [Homo sapiens]
          Length = 1365

 Score = 2848 bits (7383), Expect = 0.0
 Identities = 1365/1365 (100%), Positives = 1365/1365 (100%)

Query: 1    MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG 60
            MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG
Sbjct: 1    MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG 60

Query: 61   VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG 120
            VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG
Sbjct: 61   VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG 120

Query: 121  SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE 180
            SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE
Sbjct: 121  SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE 180

Query: 181  QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV 240
            QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV
Sbjct: 181  QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV 240

Query: 241  SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ 300
            SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ
Sbjct: 241  SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ 300

Query: 301  APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA 360
            APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA
Sbjct: 301  APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA 360

Query: 361  KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK 420
            KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK
Sbjct: 361  KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK 420

Query: 421  STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG 480
            STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG
Sbjct: 421  STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG 480

Query: 481  EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE 540
            EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE
Sbjct: 481  EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE 540

Query: 541  AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR 600
            AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR
Sbjct: 541  AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR 600

Query: 601  NRASTAASSALGFSKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSER 660
            NRASTAASSALGFSKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSER
Sbjct: 601  NRASTAASSALGFSKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSER 660

Query: 661  GVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVC 720
            GVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVC
Sbjct: 661  GVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVC 720

Query: 721  KESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKG 780
            KESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKG
Sbjct: 721  KESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKG 780

Query: 781  KMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNVSWCFVCSKG 840
            KMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNVSWCFVCSKG
Sbjct: 781  KMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNVSWCFVCSKG 840

Query: 841  GSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCH 900
            GSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCH
Sbjct: 841  GSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCH 900

Query: 901  PKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKN 960
            PKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKN
Sbjct: 901  PKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKN 960

Query: 961  ALQEAEARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKP 1020
            ALQEAEARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKP
Sbjct: 961  ALQEAEARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKP 1020

Query: 1021 TDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAK 1080
            TDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAK
Sbjct: 1021 TDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAK 1080

Query: 1081 RDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFM 1140
            RDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFM
Sbjct: 1081 RDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFM 1140

Query: 1141 NHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSG 1200
            NHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSG
Sbjct: 1141 NHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSG 1200

Query: 1201 FLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCT 1260
            FLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCT
Sbjct: 1201 FLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCT 1260

Query: 1261 KAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGR 1320
            KAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGR
Sbjct: 1261 KAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGR 1320

Query: 1321 SYCCEHDLGAASVRSTKTEKPPPEPGKPKGKRRRRRGWRRVTEGK 1365
            SYCCEHDLGAASVRSTKTEKPPPEPGKPKGKRRRRRGWRRVTEGK
Sbjct: 1321 SYCCEHDLGAASVRSTKTEKPPPEPGKPKGKRRRRRGWRRVTEGK 1365


>gi|19913350 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
            [Homo sapiens]
          Length = 1365

 Score = 2848 bits (7383), Expect = 0.0
 Identities = 1365/1365 (100%), Positives = 1365/1365 (100%)

Query: 1    MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG 60
            MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG
Sbjct: 1    MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG 60

Query: 61   VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG 120
            VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG
Sbjct: 61   VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG 120

Query: 121  SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE 180
            SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE
Sbjct: 121  SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE 180

Query: 181  QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV 240
            QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV
Sbjct: 181  QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV 240

Query: 241  SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ 300
            SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ
Sbjct: 241  SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ 300

Query: 301  APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA 360
            APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA
Sbjct: 301  APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA 360

Query: 361  KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK 420
            KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK
Sbjct: 361  KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK 420

Query: 421  STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG 480
            STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG
Sbjct: 421  STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG 480

Query: 481  EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE 540
            EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE
Sbjct: 481  EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE 540

Query: 541  AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR 600
            AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR
Sbjct: 541  AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR 600

Query: 601  NRASTAASSALGFSKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSER 660
            NRASTAASSALGFSKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSER
Sbjct: 601  NRASTAASSALGFSKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSER 660

Query: 661  GVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVC 720
            GVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVC
Sbjct: 661  GVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVC 720

Query: 721  KESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKG 780
            KESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKG
Sbjct: 721  KESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKG 780

Query: 781  KMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNVSWCFVCSKG 840
            KMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNVSWCFVCSKG
Sbjct: 781  KMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNVSWCFVCSKG 840

Query: 841  GSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCH 900
            GSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCH
Sbjct: 841  GSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCH 900

Query: 901  PKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKN 960
            PKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKN
Sbjct: 901  PKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKN 960

Query: 961  ALQEAEARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKP 1020
            ALQEAEARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKP
Sbjct: 961  ALQEAEARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKP 1020

Query: 1021 TDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAK 1080
            TDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAK
Sbjct: 1021 TDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAK 1080

Query: 1081 RDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFM 1140
            RDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFM
Sbjct: 1081 RDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFM 1140

Query: 1141 NHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSG 1200
            NHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSG
Sbjct: 1141 NHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSG 1200

Query: 1201 FLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCT 1260
            FLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCT
Sbjct: 1201 FLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCT 1260

Query: 1261 KAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGR 1320
            KAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGR
Sbjct: 1261 KAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGR 1320

Query: 1321 SYCCEHDLGAASVRSTKTEKPPPEPGKPKGKRRRRRGWRRVTEGK 1365
            SYCCEHDLGAASVRSTKTEKPPPEPGKPKGKRRRRRGWRRVTEGK
Sbjct: 1321 SYCCEHDLGAASVRSTKTEKPPPEPGKPKGKRRRRRGWRRVTEGK 1365


>gi|19913348 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
            [Homo sapiens]
          Length = 1365

 Score = 2848 bits (7383), Expect = 0.0
 Identities = 1365/1365 (100%), Positives = 1365/1365 (100%)

Query: 1    MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG 60
            MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG
Sbjct: 1    MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG 60

Query: 61   VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG 120
            VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG
Sbjct: 61   VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG 120

Query: 121  SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE 180
            SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE
Sbjct: 121  SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE 180

Query: 181  QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV 240
            QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV
Sbjct: 181  QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV 240

Query: 241  SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ 300
            SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ
Sbjct: 241  SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ 300

Query: 301  APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA 360
            APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA
Sbjct: 301  APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA 360

Query: 361  KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK 420
            KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK
Sbjct: 361  KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK 420

Query: 421  STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG 480
            STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG
Sbjct: 421  STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG 480

Query: 481  EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE 540
            EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE
Sbjct: 481  EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE 540

Query: 541  AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR 600
            AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR
Sbjct: 541  AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR 600

Query: 601  NRASTAASSALGFSKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSER 660
            NRASTAASSALGFSKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSER
Sbjct: 601  NRASTAASSALGFSKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSER 660

Query: 661  GVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVC 720
            GVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVC
Sbjct: 661  GVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVC 720

Query: 721  KESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKG 780
            KESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKG
Sbjct: 721  KESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKG 780

Query: 781  KMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNVSWCFVCSKG 840
            KMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNVSWCFVCSKG
Sbjct: 781  KMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNVSWCFVCSKG 840

Query: 841  GSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCH 900
            GSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCH
Sbjct: 841  GSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCH 900

Query: 901  PKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKN 960
            PKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKN
Sbjct: 901  PKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKN 960

Query: 961  ALQEAEARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKP 1020
            ALQEAEARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKP
Sbjct: 961  ALQEAEARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKP 1020

Query: 1021 TDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAK 1080
            TDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAK
Sbjct: 1021 TDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAK 1080

Query: 1081 RDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFM 1140
            RDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFM
Sbjct: 1081 RDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFM 1140

Query: 1141 NHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSG 1200
            NHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSG
Sbjct: 1141 NHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSG 1200

Query: 1201 FLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCT 1260
            FLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCT
Sbjct: 1201 FLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCT 1260

Query: 1261 KAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGR 1320
            KAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGR
Sbjct: 1261 KAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGR 1320

Query: 1321 SYCCEHDLGAASVRSTKTEKPPPEPGKPKGKRRRRRGWRRVTEGK 1365
            SYCCEHDLGAASVRSTKTEKPPPEPGKPKGKRRRRRGWRRVTEGK
Sbjct: 1321 SYCCEHDLGAASVRSTKTEKPPPEPGKPKGKRRRRRGWRRVTEGK 1365


>gi|109633019 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
            [Homo sapiens]
          Length = 1365

 Score = 2848 bits (7383), Expect = 0.0
 Identities = 1365/1365 (100%), Positives = 1365/1365 (100%)

Query: 1    MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG 60
            MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG
Sbjct: 1    MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG 60

Query: 61   VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG 120
            VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG
Sbjct: 61   VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG 120

Query: 121  SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE 180
            SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE
Sbjct: 121  SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE 180

Query: 181  QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV 240
            QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV
Sbjct: 181  QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV 240

Query: 241  SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ 300
            SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ
Sbjct: 241  SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ 300

Query: 301  APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA 360
            APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA
Sbjct: 301  APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA 360

Query: 361  KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK 420
            KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK
Sbjct: 361  KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK 420

Query: 421  STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG 480
            STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG
Sbjct: 421  STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG 480

Query: 481  EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE 540
            EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE
Sbjct: 481  EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE 540

Query: 541  AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR 600
            AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR
Sbjct: 541  AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR 600

Query: 601  NRASTAASSALGFSKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSER 660
            NRASTAASSALGFSKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSER
Sbjct: 601  NRASTAASSALGFSKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSER 660

Query: 661  GVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVC 720
            GVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVC
Sbjct: 661  GVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVC 720

Query: 721  KESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKG 780
            KESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKG
Sbjct: 721  KESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKG 780

Query: 781  KMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNVSWCFVCSKG 840
            KMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNVSWCFVCSKG
Sbjct: 781  KMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNVSWCFVCSKG 840

Query: 841  GSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCH 900
            GSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCH
Sbjct: 841  GSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCH 900

Query: 901  PKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKN 960
            PKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKN
Sbjct: 901  PKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKN 960

Query: 961  ALQEAEARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKP 1020
            ALQEAEARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKP
Sbjct: 961  ALQEAEARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKP 1020

Query: 1021 TDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAK 1080
            TDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAK
Sbjct: 1021 TDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAK 1080

Query: 1081 RDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFM 1140
            RDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFM
Sbjct: 1081 RDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFM 1140

Query: 1141 NHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSG 1200
            NHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSG
Sbjct: 1141 NHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSG 1200

Query: 1201 FLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCT 1260
            FLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCT
Sbjct: 1201 FLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCT 1260

Query: 1261 KAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGR 1320
            KAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGR
Sbjct: 1261 KAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGR 1320

Query: 1321 SYCCEHDLGAASVRSTKTEKPPPEPGKPKGKRRRRRGWRRVTEGK 1365
            SYCCEHDLGAASVRSTKTEKPPPEPGKPKGKRRRRRGWRRVTEGK
Sbjct: 1321 SYCCEHDLGAASVRSTKTEKPPPEPGKPKGKRRRRRGWRRVTEGK 1365


>gi|6594683 Wolf-Hirschhorn syndrome candidate 1 protein isoform 4
           [Homo sapiens]
          Length = 629

 Score = 1243 bits (3217), Expect = 0.0
 Identities = 628/628 (100%), Positives = 628/628 (100%)

Query: 1   MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG 60
           MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG
Sbjct: 1   MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG 60

Query: 61  VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG 120
           VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG
Sbjct: 61  VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG 120

Query: 121 SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE 180
           SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE
Sbjct: 121 SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE 180

Query: 181 QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV 240
           QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV
Sbjct: 181 QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV 240

Query: 241 SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ 300
           SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ
Sbjct: 241 SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ 300

Query: 301 APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA 360
           APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA
Sbjct: 301 APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA 360

Query: 361 KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK 420
           KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK
Sbjct: 361 KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK 420

Query: 421 STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG 480
           STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG
Sbjct: 421 STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG 480

Query: 481 EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE 540
           EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE
Sbjct: 481 EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE 540

Query: 541 AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR 600
           AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR
Sbjct: 541 AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR 600

Query: 601 NRASTAASSALGFSKSSSPSASLTENEV 628
           NRASTAASSALGFSKSSSPSASLTENEV
Sbjct: 601 NRASTAASSALGFSKSSSPSASLTENEV 628


>gi|19913356 Wolf-Hirschhorn syndrome candidate 1 protein isoform 3
           [Homo sapiens]
          Length = 647

 Score = 1243 bits (3215), Expect = 0.0
 Identities = 628/632 (99%), Positives = 629/632 (99%)

Query: 1   MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG 60
           MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG
Sbjct: 1   MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG 60

Query: 61  VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG 120
           VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG
Sbjct: 61  VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG 120

Query: 121 SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE 180
           SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE
Sbjct: 121 SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE 180

Query: 181 QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV 240
           QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV
Sbjct: 181 QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV 240

Query: 241 SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ 300
           SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ
Sbjct: 241 SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ 300

Query: 301 APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA 360
           APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA
Sbjct: 301 APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA 360

Query: 361 KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK 420
           KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK
Sbjct: 361 KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK 420

Query: 421 STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG 480
           STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG
Sbjct: 421 STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG 480

Query: 481 EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE 540
           EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE
Sbjct: 481 EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE 540

Query: 541 AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR 600
           AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR
Sbjct: 541 AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR 600

Query: 601 NRASTAASSALGFSKSSSPSASLTENEVSDSP 632
           NRASTAASSALGFSKSSSPSASLTENE+   P
Sbjct: 601 NRASTAASSALGFSKSSSPSASLTENELLWEP 632


>gi|13699811 WHSC1L1 protein isoform long [Homo sapiens]
          Length = 1437

 Score = 1177 bits (3046), Expect = 0.0
 Identities = 617/1308 (47%), Positives = 800/1308 (61%), Gaps = 129/1308 (9%)

Query: 111  PPNTTPIKNGSPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRK 170
            P    P K GSPEIKLKITKT  NG+ LFESS+CGD   +V  SE    K E++ +  RK
Sbjct: 140  PQTVIPKKTGSPEIKLKITKTIQNGRELFESSLCGDLLNEVQASEHTKSKHESR-KEKRK 198

Query: 171  RSIKYDSLLEQGLVEAALVS-----------KISSPSDK--KIPAKKESCP--------- 208
            +S K+DS   +      +             ++ + S+K  + P  KE  P         
Sbjct: 199  KSNKHDSSRSEERKSHKIPKLEPEEQNRPNERVDTVSEKPREEPVLKEEAPVQPILSSVP 258

Query: 209  ----NTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHV 264
                +TG      +K+ VGDLVWSKV  YPWWPCMVS+DP L  +TK+    + AR+YHV
Sbjct: 259  TTEVSTG------VKFQVGDLVWSKVGTYPWWPCMVSSDPQLEVHTKIN--TRGAREYHV 310

Query: 265  QFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEM 324
            QFF + PERAW+ EK +  ++G  Q+E+L  E+ KQA   +EK K+ KP   + RAQW++
Sbjct: 311  QFFSNQPERAWVHEKRVREYKGHKQYEELLAEATKQASNHSEKQKIRKPRPQRERAQWDI 370

Query: 325  GIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVAKEAGIAAESLGEMAESSGVSEEAA 384
            GI  AE+A  M+ EER  ++TF+Y+  Q       AK++  +   + +      V     
Sbjct: 371  GIAHAEKALKMTREERIEQYTFIYIDKQPEEALSQAKKSVASKTEVKKTRRPRSVLNTQP 430

Query: 385  E--NPKSVREECIPMKRRRRAKLCSSAETLESHPDIGKSTPQKTAEADPRRGVGSPPGRK 442
            E  N   V       + RR ++   ++   E  P +      KTA A  R+ + +     
Sbjct: 431  EQTNAGEVASSLSSTEIRRHSQRRHTSAEEEEPPPV--KIAWKTAAA--RKSLPASITMH 486

Query: 443  KTTVSMPRSRKGDAASQFLVFCQKHR-------DEVVAEHPDASGEEIEELLRSQWSLLS 495
            K ++ + +           VF  ++        D+ V       G + E  +R Q  L+ 
Sbjct: 487  KGSLDLQKCNMSPVVKIEQVFALQNATGDGKFIDQFVYS-TKGIGNKTEISVRGQDRLII 545

Query: 496  EKQRARYNTKFALVAPVQAEEDS-GNVNGKKRNHTKRIQDPTEDAEAEDTPRKRLRTDKH 554
                 R       V+  +A   S G+V  K++  + R +  +E +  E  P+K+++ ++ 
Sbjct: 546  STPNQRNEKPTQSVSSPEATSGSTGSVEKKQQRRSIRTRSESEKS-TEVVPKKKIKKEQV 604

Query: 555  SLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKRNRASTAASSALGFS 614
                 +T+   T +T   K                +SD+CKPLKKR+RAST         
Sbjct: 605  -----ETVPQATVKTGLQKG------------ASEISDSCKPLKKRSRASTDVEMTSSAY 647

Query: 615  KSSSPSASLTENEVSDSPGDEPSESPYESADETQTEV-SVSSKKSERGV-TAKKEYVCQL 672
            + +S S S   +++    G +  +SP  +AD   ++V S+ S  S RG   +KK+ VCQ+
Sbjct: 648  RDTSDSDSRGLSDLQVGFGKQV-DSPSATADADVSDVQSMDSSLSRRGTGMSKKDTVCQI 706

Query: 673  CEKPG-SLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVCKESKTDVKRCV 731
            CE  G SL+ CEG CC  FHL CLGL+  P+ +F C EC +G H CF CK S  DVKRC 
Sbjct: 707  CESSGDSLIPCEGECCKHFHLECLGLASLPDSKFICMECKTGQHPCFSCKVSGKDVKRCS 766

Query: 732  VTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKGKMMRCVRCPVA 791
            V  CGKFYHEACV+K+P  +FES+GFRCP H C +C      + + SKG+MMRC+RCPVA
Sbjct: 767  VGACGKFYHEACVRKFPTAIFESKGFRCPQHCCSACSMEKDIH-KASKGRMMRCLRCPVA 825

Query: 792  YHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNVSWCFVCS------------- 838
            YHSGDAC+AAG  +++S  +IC+ H    K   + + VNV +CFVC+             
Sbjct: 826  YHSGDACIAAGSMLVSSYILICSNH---SKRSSNSSAVNVGFCFVCARGLIVQDHSDPMF 882

Query: 839  ------------------------------------KGGSLLCCESCPAAFHPDCLNIEM 862
                                                KGG LLCCESCPA+FHP+CL+IEM
Sbjct: 883  SSYAYKSHYLLNESNRAELMKLPMIPSSSASKKKCEKGGRLLCCESCPASFHPECLSIEM 942

Query: 863  PDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFPVFF 922
            P+G W CNDC+AGKKLH++ I+WVKLGNYRWWPAE+C+P++VP NIQ +KH++G+FPVFF
Sbjct: 943  PEGCWNCNDCKAGKKLHYKQIVWVKLGNYRWWPAEICNPRSVPLNIQGLKHDLGDFPVFF 1002

Query: 923  FGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNALQEAEARFREIKLQREARETQ 982
            FGS DYYW HQ RVFPY+EGD+ S  +G   I + FK AL+EA  RF+E+K QRE++E  
Sbjct: 1003 FGSHDYYWVHQGRVFPYVEGDK-SFAEGQTSINKTFKKALEEAAKRFQELKAQRESKEAL 1061

Query: 983  ESE---RKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKPTDENPCGFDSECLNRMLMF 1039
            E E   RKPPPYKHIK NK  GKVQI  AD+SEIP+CNCKP DENPCG +SECLNRML +
Sbjct: 1062 EIEKNSRKPPPYKHIKANKVIGKVQIQVADLSEIPRCNCKPADENPCGLESECLNRMLQY 1121

Query: 1040 ECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDE 1099
            ECHPQVCPAG+ CQNQCFTKR YP+ +IIKT+ +GWGL  KR I+KGEFVNEYVGELIDE
Sbjct: 1122 ECHPQVCPAGDRCQNQCFTKRLYPDAEIIKTERRGWGLRTKRSIKKGEFVNEYVGELIDE 1181

Query: 1100 EECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDT 1159
            EEC  RIK AHEN +T+FYMLT+ KDRIIDAGPKGNYSRFMNHSC PNCET KWTVNGD 
Sbjct: 1182 EECRLRIKRAHENSVTNFYMLTVTKDRIIDAGPKGNYSRFMNHSCNPNCETQKWTVNGDV 1241

Query: 1160 RVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSGFLGDRPKTSTTLSSEEKGK 1219
            RVGLFA+CDIPAG ELTFNYNLDCLGN +T C CGA NCSGFLG RPK++   ++EEK K
Sbjct: 1242 RVGLFALCDIPAGMELTFNYNLDCLGNGRTECHCGADNCSGFLGVRPKSACASTNEEKAK 1301

Query: 1220 KTKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCTKAYHLSCLGLGKRPFGKWE 1279
              K K +RR+ K E K+  ED CF+CGDGG+LV+CD+K C KAYHL CL L + P+GKWE
Sbjct: 1302 NAKLKQKRRKIKTEPKQMHEDYCFQCGDGGELVMCDKKDCPKAYHLLCLNLTQPPYGKWE 1361

Query: 1280 CPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGRSYCCEHD 1327
            CPWH CD C   + SFC  CP+SFCK+H+ G       +GR  C EHD
Sbjct: 1362 CPWHQCDECSSAAVSFCEFCPHSFCKDHEKGALVPSALEGRLCCSEHD 1409



 Score = 38.5 bits (88), Expect = 0.044
 Identities = 35/121 (28%), Positives = 45/121 (37%), Gaps = 20/121 (16%)

Query: 1231 KGEGKRQSEDECFRC-GDGGQLVLCDRKFCTKAYHLSCLGLGKRPFGKWEC--------P 1281
            +G G  + +  C  C   G  L+ C+ + C K +HL CLGL   P  K+ C        P
Sbjct: 693  RGTGMSKKDTVCQICESSGDSLIPCEGE-CCKHFHLECLGLASLPDSKFICMECKTGQHP 751

Query: 1282 WHHCDVCGKP----STSFC-----HLCPNSFCKEHQDGTAFSCTPDGRSYC-CEHDLGAA 1331
               C V GK     S   C       C   F     +   F C     S C  E D+  A
Sbjct: 752  CFSCKVSGKDVKRCSVGACGKFYHEACVRKFPTAIFESKGFRCPQHCCSACSMEKDIHKA 811

Query: 1332 S 1332
            S
Sbjct: 812  S 812


>gi|27477095 nuclear receptor binding SET domain protein 1 isoform a
            [Homo sapiens]
          Length = 2427

 Score = 1051 bits (2719), Expect = 0.0
 Identities = 477/765 (62%), Positives = 582/765 (76%), Gaps = 12/765 (1%)

Query: 595  KPLKKRNRASTAASSALGFSKSSSPSASLTENEVSDSP---GDEPSESPYESADETQTEV 651
            KP K++ +   AA       K+   S  +  +E    P      P E+  E  +      
Sbjct: 1198 KPRKRKRQRHAAAKMQCKKVKNDDSSKEIPGSEGELMPHRTATSPKETVEEGVEHDPGMP 1257

Query: 652  SVSSKKSERGV-TAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSEC 710
            +    + ERG   A KE VCQ CEK G LLLCE  CCGAFHL CLGL+  P G+F C+EC
Sbjct: 1258 ASKKMQGERGGGAALKENVCQNCEKLGELLLCEAQCCGAFHLECLGLTEMPRGKFICNEC 1317

Query: 711  ASGIHSCFVCKESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHAS 770
             +GIH+CFVCK+S  DVKRC++  CGKFYHE CV+KYP TV +++GFRC LH C++CHA+
Sbjct: 1318 RTGIHTCFVCKQSGEDVKRCLLPLCGKFYHEECVQKYPPTVMQNKGFRCSLHICITCHAA 1377

Query: 771  NPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVN 830
            NP+N   SKG++MRCVRCPVAYH+ D CLAAG  ++ASNSIIC  HFT R+G R+H HVN
Sbjct: 1378 NPANVSASKGRLMRCVRCPVAYHANDFCLAAGSKILASNSIICPNHFTPRRGCRNHEHVN 1437

Query: 831  VSWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGN 890
            VSWCFVCS+GGSLLCC+SCPAAFH +CLNI++P+G+W+CNDC+AGKK H+++I+WVK+G 
Sbjct: 1438 VSWCFVCSEGGSLLCCDSCPAAFHRECLNIDIPEGNWYCNDCKAGKKPHYREIVWVKVGR 1497

Query: 891  YRWWPAEVCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQG 950
            YRWWPAE+CHP+ VP NI KM+H++GEFPV FFGS DY WTHQARVFPYMEGD  S+ + 
Sbjct: 1498 YRWWPAEICHPRAVPSNIDKMRHDVGEFPVLFFGSNDYLWTHQARVFPYMEGDVSSKDKM 1557

Query: 951  VRGIGRVFKNALQEAEARFREIKLQREARETQE---SERKPPPYKHIKVNKPYGKVQIYT 1007
             +G+   +K ALQEA ARF E+K Q+E R+ QE   +++KPPPYKHIKVN+P G+VQI+T
Sbjct: 1558 GKGVDGTYKKALQEAAARFEELKAQKELRQLQEDRKNDKKPPPYKHIKVNRPIGRVQIFT 1617

Query: 1008 ADISEIPKCNCKPTDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKI 1067
            AD+SEIP+CNCK TDENPCG DSEC+NRML++ECHP VCPAG  CQNQCF+KRQYPE +I
Sbjct: 1618 ADLSEIPRCNCKATDENPCGIDSECINRMLLYECHPTVCPAGGRCQNQCFSKRQYPEVEI 1677

Query: 1068 IKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRI 1127
             +T  +GWGL  K DI+KGEFVNEYVGELIDEEEC ARI++A E+DIT+FYMLT+DKDRI
Sbjct: 1678 FRTLQRGWGLRTKTDIKKGEFVNEYVGELIDEEECRARIRYAQEHDITNFYMLTLDKDRI 1737

Query: 1128 IDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNE 1187
            IDAGPKGNY+RFMNH CQPNCET KW+VNGDTRVGLFA+ DI AGTELTFNYNL+CLGN 
Sbjct: 1738 IDAGPKGNYARFMNHCCQPNCETQKWSVNGDTRVGLFALSDIKAGTELTFNYNLECLGNG 1797

Query: 1188 KTVCRCGASNCSGFLGDRPKTSTTLSSEEKGKKTKKKTR-RRRAKGEGKRQSEDECFRCG 1246
            KTVC+CGA NCSGFLG RPK    +++EEK KK KKK + +RR +GE  ++ EDECF CG
Sbjct: 1798 KTVCKCGAPNCSGFLGVRPKNQP-IATEEKSKKFKKKQQGKRRTQGEITKEREDECFSCG 1856

Query: 1247 DGGQLVLCDRKFCTKAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKE 1306
            D GQLV C +  C K YH  CL L KRP GKWECPWH CD+CGK + SFC +CP+SFCK+
Sbjct: 1857 DAGQLVSCKKPGCPKVYHADCLNLTKRPAGKWECPWHQCDICGKEAASFCEMCPSSFCKQ 1916

Query: 1307 HQDGTAFSCTPDGRSYCCEHD-LGAASVRSTKTEK--PPPEPGKP 1348
            H++G  F    DGR  C EHD  G   +   +  +  PPP P  P
Sbjct: 1917 HREGMLFISKLDGRLSCTEHDPCGPNPLEPGEIREYVPPPVPLPP 1961



 Score = 98.6 bits (244), Expect = 4e-20
 Identities = 52/143 (36%), Positives = 84/143 (58%), Gaps = 16/143 (11%)

Query: 193 SSPSDKKIP---AKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSY 249
           SS + +++P    KK+S P         LKY VGDL+W+K    PWWPC + +DPL++++
Sbjct: 31  SSSTSQELPFCQPKKKSTP---------LKYEVGDLIWAKFKRRPWWPCRICSDPLINTH 81

Query: 250 TKLK-GQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKI 308
           +K+K   ++  RQY+V+ FGD  ERAW+  K++V FEG  QFE+L      +   K ++ 
Sbjct: 82  SKMKVSNRRPYRQYYVEAFGDPSERAWVAGKAIVMFEGRHQFEEL---PVLRRRGKQKEK 138

Query: 309 KLLKPISGKLRAQWEMGIVQAEE 331
                +  K+ ++WE  +  AE+
Sbjct: 139 GYRHKVPQKILSKWEASVGLAEQ 161



 Score = 30.8 bits (68), Expect = 9.3
 Identities = 11/34 (32%), Positives = 16/34 (47%), Gaps = 2/34 (5%)

Query: 868 FCNDCRAGKKLHFQ--DIIWVKLGNYRWWPAEVC 899
           FC   +    L ++  D+IW K     WWP  +C
Sbjct: 40  FCQPKKKSTPLKYEVGDLIWAKFKRRPWWPCRIC 73


>gi|19923586 nuclear receptor binding SET domain protein 1 isoform b
            [Homo sapiens]
          Length = 2696

 Score = 1051 bits (2719), Expect = 0.0
 Identities = 477/765 (62%), Positives = 582/765 (76%), Gaps = 12/765 (1%)

Query: 595  KPLKKRNRASTAASSALGFSKSSSPSASLTENEVSDSP---GDEPSESPYESADETQTEV 651
            KP K++ +   AA       K+   S  +  +E    P      P E+  E  +      
Sbjct: 1467 KPRKRKRQRHAAAKMQCKKVKNDDSSKEIPGSEGELMPHRTATSPKETVEEGVEHDPGMP 1526

Query: 652  SVSSKKSERGV-TAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSEC 710
            +    + ERG   A KE VCQ CEK G LLLCE  CCGAFHL CLGL+  P G+F C+EC
Sbjct: 1527 ASKKMQGERGGGAALKENVCQNCEKLGELLLCEAQCCGAFHLECLGLTEMPRGKFICNEC 1586

Query: 711  ASGIHSCFVCKESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHAS 770
             +GIH+CFVCK+S  DVKRC++  CGKFYHE CV+KYP TV +++GFRC LH C++CHA+
Sbjct: 1587 RTGIHTCFVCKQSGEDVKRCLLPLCGKFYHEECVQKYPPTVMQNKGFRCSLHICITCHAA 1646

Query: 771  NPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVN 830
            NP+N   SKG++MRCVRCPVAYH+ D CLAAG  ++ASNSIIC  HFT R+G R+H HVN
Sbjct: 1647 NPANVSASKGRLMRCVRCPVAYHANDFCLAAGSKILASNSIICPNHFTPRRGCRNHEHVN 1706

Query: 831  VSWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGN 890
            VSWCFVCS+GGSLLCC+SCPAAFH +CLNI++P+G+W+CNDC+AGKK H+++I+WVK+G 
Sbjct: 1707 VSWCFVCSEGGSLLCCDSCPAAFHRECLNIDIPEGNWYCNDCKAGKKPHYREIVWVKVGR 1766

Query: 891  YRWWPAEVCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQG 950
            YRWWPAE+CHP+ VP NI KM+H++GEFPV FFGS DY WTHQARVFPYMEGD  S+ + 
Sbjct: 1767 YRWWPAEICHPRAVPSNIDKMRHDVGEFPVLFFGSNDYLWTHQARVFPYMEGDVSSKDKM 1826

Query: 951  VRGIGRVFKNALQEAEARFREIKLQREARETQE---SERKPPPYKHIKVNKPYGKVQIYT 1007
             +G+   +K ALQEA ARF E+K Q+E R+ QE   +++KPPPYKHIKVN+P G+VQI+T
Sbjct: 1827 GKGVDGTYKKALQEAAARFEELKAQKELRQLQEDRKNDKKPPPYKHIKVNRPIGRVQIFT 1886

Query: 1008 ADISEIPKCNCKPTDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKI 1067
            AD+SEIP+CNCK TDENPCG DSEC+NRML++ECHP VCPAG  CQNQCF+KRQYPE +I
Sbjct: 1887 ADLSEIPRCNCKATDENPCGIDSECINRMLLYECHPTVCPAGGRCQNQCFSKRQYPEVEI 1946

Query: 1068 IKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRI 1127
             +T  +GWGL  K DI+KGEFVNEYVGELIDEEEC ARI++A E+DIT+FYMLT+DKDRI
Sbjct: 1947 FRTLQRGWGLRTKTDIKKGEFVNEYVGELIDEEECRARIRYAQEHDITNFYMLTLDKDRI 2006

Query: 1128 IDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNE 1187
            IDAGPKGNY+RFMNH CQPNCET KW+VNGDTRVGLFA+ DI AGTELTFNYNL+CLGN 
Sbjct: 2007 IDAGPKGNYARFMNHCCQPNCETQKWSVNGDTRVGLFALSDIKAGTELTFNYNLECLGNG 2066

Query: 1188 KTVCRCGASNCSGFLGDRPKTSTTLSSEEKGKKTKKKTR-RRRAKGEGKRQSEDECFRCG 1246
            KTVC+CGA NCSGFLG RPK    +++EEK KK KKK + +RR +GE  ++ EDECF CG
Sbjct: 2067 KTVCKCGAPNCSGFLGVRPKNQP-IATEEKSKKFKKKQQGKRRTQGEITKEREDECFSCG 2125

Query: 1247 DGGQLVLCDRKFCTKAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKE 1306
            D GQLV C +  C K YH  CL L KRP GKWECPWH CD+CGK + SFC +CP+SFCK+
Sbjct: 2126 DAGQLVSCKKPGCPKVYHADCLNLTKRPAGKWECPWHQCDICGKEAASFCEMCPSSFCKQ 2185

Query: 1307 HQDGTAFSCTPDGRSYCCEHD-LGAASVRSTKTEK--PPPEPGKP 1348
            H++G  F    DGR  C EHD  G   +   +  +  PPP P  P
Sbjct: 2186 HREGMLFISKLDGRLSCTEHDPCGPNPLEPGEIREYVPPPVPLPP 2230



 Score = 98.6 bits (244), Expect = 4e-20
 Identities = 52/143 (36%), Positives = 84/143 (58%), Gaps = 16/143 (11%)

Query: 193 SSPSDKKIP---AKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSY 249
           SS + +++P    KK+S P         LKY VGDL+W+K    PWWPC + +DPL++++
Sbjct: 300 SSSTSQELPFCQPKKKSTP---------LKYEVGDLIWAKFKRRPWWPCRICSDPLINTH 350

Query: 250 TKLK-GQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKI 308
           +K+K   ++  RQY+V+ FGD  ERAW+  K++V FEG  QFE+L      +   K ++ 
Sbjct: 351 SKMKVSNRRPYRQYYVEAFGDPSERAWVAGKAIVMFEGRHQFEEL---PVLRRRGKQKEK 407

Query: 309 KLLKPISGKLRAQWEMGIVQAEE 331
                +  K+ ++WE  +  AE+
Sbjct: 408 GYRHKVPQKILSKWEASVGLAEQ 430



 Score = 39.3 bits (90), Expect = 0.026
 Identities = 55/213 (25%), Positives = 83/213 (38%), Gaps = 36/213 (16%)

Query: 24  APEILGS--ANGKTPSCEVNRECSVFLSKAQLSSSLQEGVMQKFNGHDALP-FIPADKLK 80
           APE   S   NG++   E    C++ LS          G  Q   G D+   +IP  +L+
Sbjct: 24  APEDKDSPFGNGQSNFSEPLNGCTMQLSTVS-------GTSQNAYGQDSPSCYIPLRRLQ 76

Query: 81  DLTSRVFNGE--PGAHDAKLRFESQEMKG--IGTPPNTT---------------PIKNGS 121
           DL S + N E   G+ D    F+  E       TP   T               P  N S
Sbjct: 77  DLASMI-NVEYLNGSADGSESFQDPEKSDSRAQTPIVCTSLSPGGPTALAMKQEPSCNNS 135

Query: 122 PEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKA------RRNRKRSIKY 175
           PE+++K+TKT  NG   FE+  C D A   S+ +      E+++            +  Y
Sbjct: 136 PELQVKVTKTIKNGFLHFENFTCVDDADVDSEMDPEQPVTEDESIEEIFEETQTNATCNY 195

Query: 176 DSLLEQGLVEAALVSKISSPSDKKIPAKKESCP 208
           ++  E G+  A    + S+P  +    K    P
Sbjct: 196 ETKSENGVKVAMGSEQDSTPESRHGAVKSPFLP 228



 Score = 30.8 bits (68), Expect = 9.3
 Identities = 11/34 (32%), Positives = 16/34 (47%), Gaps = 2/34 (5%)

Query: 868 FCNDCRAGKKLHFQ--DIIWVKLGNYRWWPAEVC 899
           FC   +    L ++  D+IW K     WWP  +C
Sbjct: 309 FCQPKKKSTPLKYEVGDLIWAKFKRRPWWPCRIC 342


>gi|197313748 SET domain containing 2 [Homo sapiens]
          Length = 2564

 Score =  203 bits (516), Expect = 1e-51
 Identities = 99/231 (42%), Positives = 140/231 (60%), Gaps = 14/231 (6%)

Query: 1015 KCNCKPTDENP-------CGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKI 1067
            +C C P  ++        CG D  CLNR+LM EC  + CP G++C N+ F ++Q+ + ++
Sbjct: 1498 QCECTPLSKDERAQGEIACGED--CLNRLLMIECSSR-CPNGDYCSNRRFQRKQHADVEV 1554

Query: 1068 IKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRI 1127
            I T+ KGWGL A +D+    FV EY GE++D +E  AR+K    N   H+Y + +  D I
Sbjct: 1555 ILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHKEFKARVKEYARNKNIHYYFMALKNDEI 1614

Query: 1128 IDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNE 1187
            IDA  KGN SRFMNHSC+PNCET KWTVNG  RVG F    +P+G+ELTF+Y     G E
Sbjct: 1615 IDATQKGNCSRFMNHSCEPNCETQKWTVNGQLRVGFFTTKLVPSGSELTFDYQFQRYGKE 1674

Query: 1188 KTVCRCGASNCSGFLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQS 1238
               C CG++NC G+LG   + S   +    G K KK+  R++   +G+ ++
Sbjct: 1675 AQKCFCGSANCRGYLGGENRVSIRAA----GGKMKKERSRKKDSVDGELEA 1721


>gi|13699813 WHSC1L1 protein isoform short [Homo sapiens]
          Length = 645

 Score =  202 bits (514), Expect = 2e-51
 Identities = 155/500 (31%), Positives = 241/500 (48%), Gaps = 58/500 (11%)

Query: 111 PPNTTPIKNGSPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRK 170
           P    P K GSPEIKLKITKT  NG+ LFESS+CGD   +V  SE    K E++ +  RK
Sbjct: 140 PQTVIPKKTGSPEIKLKITKTIQNGRELFESSLCGDLLNEVQASEHTKSKHESR-KEKRK 198

Query: 171 RSIKYDSLLEQGLVEAALVS-----------KISSPSDK--KIPAKKESCP--------- 208
           +S K+DS   +      +             ++ + S+K  + P  KE  P         
Sbjct: 199 KSNKHDSSRSEERKSHKIPKLEPEEQNRPNERVDTVSEKPREEPVLKEEAPVQPILSSVP 258

Query: 209 ----NTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHV 264
               +TG      +K+ VGDLVWSKV  YPWWPCMVS+DP L  +TK+    + AR+YHV
Sbjct: 259 TTEVSTG------VKFQVGDLVWSKVGTYPWWPCMVSSDPQLEVHTKIN--TRGAREYHV 310

Query: 265 QFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEM 324
           QFF + PERAW+ EK +  ++G  Q+E+L  E+ KQA   +EK K+ KP   + RAQW++
Sbjct: 311 QFFSNQPERAWVHEKRVREYKGHKQYEELLAEATKQASNHSEKQKIRKPRPQRERAQWDI 370

Query: 325 GIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVAKEAGIAAESLGEMAESSGVSEEAA 384
           GI  AE+A  M+ EER  ++TF+Y+  Q       AK++  +   + +      V     
Sbjct: 371 GIAHAEKALKMTREERIEQYTFIYIDKQPEEALSQAKKSVASKTEVKKTRRPRSVLNTQP 430

Query: 385 E--NPKSVREECIPMKRRRRAKLCSSAETLESHPDIGKSTPQKTAEADPRRGVGSPPGRK 442
           E  N   V       + RR ++   ++   E  P +      KTA A  R+ + +     
Sbjct: 431 EQTNAGEVASSLSSTEIRRHSQRRHTSAEEEEPPPV--KIAWKTAAA--RKSLPASITMH 486

Query: 443 KTTVSMPRSRKGDAASQFLVFC-------QKHRDEVVAEHPDASGEEIEELLRSQWSLL- 494
           K ++ + +           VF         K  D+ V       G + E  +R Q  L+ 
Sbjct: 487 KGSLDLQKCNMSPVVKIEQVFALQNATGDGKFIDQFVYS-TKGIGNKTEISVRGQDRLII 545

Query: 495 -SEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAEAEDTPRKRLRTDK 553
            +  QR    T+ ++ +P      +G+V  K++  + R +  +E +  E  P+K+++ + 
Sbjct: 546 STPNQRNEKPTQ-SVSSPEATSGSTGSVEKKQQRRSIRTRSESEKS-TEVVPKKKIKKE- 602

Query: 554 HSLRKRDTITDKTARTSSYK 573
               + +T+   T +T   K
Sbjct: 603 ----QVETVPQATVKTGLQK 618



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 20/66 (30%), Positives = 31/66 (46%), Gaps = 1/66 (1%)

Query: 875 GKKLHFQDIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFPVFFFGSK-DYYWTHQ 933
           G K    D++W K+G Y WWP  V     +  + +       E+ V FF ++ +  W H+
Sbjct: 265 GVKFQVGDLVWSKVGTYPWWPCMVSSDPQLEVHTKINTRGAREYHVQFFSNQPERAWVHE 324

Query: 934 ARVFPY 939
            RV  Y
Sbjct: 325 KRVREY 330


>gi|110349788 absent, small, or homeotic 1-like [Homo sapiens]
          Length = 2964

 Score =  185 bits (469), Expect = 3e-46
 Identities = 99/259 (38%), Positives = 147/259 (56%), Gaps = 11/259 (4%)

Query: 986  RKP--PPYKHIKVNKPYGKVQIYTADISEIPKCNCK-PTDENPCGFDSECLNRMLMFECH 1042
            +KP  P YK I+ N     V +      E   CNCK P D+   G   +CLNRM+  EC 
Sbjct: 2062 KKPDVPLYKKIRSNV---YVDVKPLSGYEATTCNCKKPDDDTRKGCVDDCLNRMIFAECS 2118

Query: 1043 PQVCPAGEFCQNQCFTKRQYPET-KIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEE 1101
            P  CP GE C NQ   + ++ +  +  + + KGWG+  K  ++ G+F+ EY+GE++ E+E
Sbjct: 2119 PNTCPCGEQCCNQRIQRHEWVQCLERFRAEEKGWGIRTKEPLKAGQFIIEYLGEVVSEQE 2178

Query: 1102 CMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRV 1161
               R+   + N   H Y L +D   +ID+   GN +RF+NHSC PNCE  KW+VNG  R+
Sbjct: 2179 FRNRMIEQYHNHSDH-YCLNLDSGMVIDSYRMGNEARFINHSCDPNCEMQKWSVNGVYRI 2237

Query: 1162 GLFAVCDIPAGTELTFNYNLDCLGNEK-TVCRCGASNCSGFLGDRPKTSTTLSSEEKGK- 1219
            GL+A+ D+PAGTELT++YN      EK  +C+CG   C G +G + +    L+S +  + 
Sbjct: 2238 GLYALKDMPAGTELTYDYNFHSFNVEKQQLCKCGFEKCRGIIGGKSQRVNGLTSSKNSQP 2297

Query: 1220 -KTKKKTRRRRAKGEGKRQ 1237
              T KK+ R + K + K +
Sbjct: 2298 MATHKKSGRSKEKRKSKHK 2316


>gi|13375930 suppressor of variegation 3-9 homolog 2 [Homo sapiens]
          Length = 350

 Score =  101 bits (251), Expect = 6e-21
 Identities = 65/185 (35%), Positives = 93/185 (50%), Gaps = 21/185 (11%)

Query: 1038 MFECHPQVCPAGEFCQNQCFTKRQYPETKIIKT-DGKGWGLVAKRDIRKGEFVNEYVGEL 1096
            ++EC+ + C  G  C N+   K       I +T +G+GWG+     I++  FV EYVGE+
Sbjct: 166  IYECNSR-CQCGPDCPNRIVQKGTQYSLCIFRTSNGRGWGVKTLVKIKRMSFVMEYVGEV 224

Query: 1097 IDEEECMARIKHAHENDITHFYMLTIDKDRI-IDAGPKGNYSRFMNHSCQPNCETLKWTV 1155
            I  EE   R +      IT+ + L  + D   +DA   GN S F+NHSC PN +     +
Sbjct: 225  ITSEEAERRGQFYDNKGITYLFDLDYESDEFTVDAARYGNVSHFVNHSCDPNLQVFNVFI 284

Query: 1156 -NGDT---RVGLFAVCDIPAGTELTFNYNLDCLGN--------------EKTVCRCGASN 1197
             N DT   R+ LF+   I AG ELTF+Y +   G+               +TVC+CGA  
Sbjct: 285  DNLDTRLPRIALFSTRTINAGEELTFDYQMKGSGDISSDSIDHSPAKKRVRTVCKCGAVT 344

Query: 1198 CSGFL 1202
            C G+L
Sbjct: 345  CRGYL 349


>gi|19923202 enhancer of zeste homolog 1 [Homo sapiens]
          Length = 747

 Score = 96.7 bits (239), Expect = 1e-19
 Identities = 61/182 (33%), Positives = 90/182 (49%), Gaps = 20/182 (10%)

Query: 1016 CNCKPTDENP---CGFDSECLNR-----MLMFECHPQVC---PAGEF-------CQNQCF 1057
            C C P  +N    C   ++C  +     + + EC P +C    A E        C+N   
Sbjct: 548  CQCNPDCQNRFPGCRCKTQCNTKQCPCYLAVRECDPDLCLTCGASEHWDCKVVSCKNCSI 607

Query: 1058 TKRQYPETKIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHF 1117
             +       +  +D  GWG   K  ++K EF++EY GELI ++E   R K  ++  ++ F
Sbjct: 608  QRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGK-VYDKYMSSF 666

Query: 1118 YMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTF 1177
             +  ++ D ++DA  KGN  RF NHS  PNC      VNGD R+G+FA   I AG EL F
Sbjct: 667  -LFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAGEELFF 725

Query: 1178 NY 1179
            +Y
Sbjct: 726  DY 727


>gi|23510384 enhancer of zeste 2 isoform b [Homo sapiens]
          Length = 707

 Score = 94.7 bits (234), Expect = 5e-19
 Identities = 58/182 (31%), Positives = 86/182 (47%), Gaps = 23/182 (12%)

Query: 1011 SEIPKCNCKP---TDENPCGFDSECLNRMLMFECHPQVC----------PAGEFCQNQCF 1057
            +  P C CK    T + PC         + + EC P +C               C+N   
Sbjct: 516  NRFPGCRCKAQCNTKQCPC--------YLAVRECDPDLCLTCGAADHWDSKNVSCKNCSI 567

Query: 1058 TKRQYPETKIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHF 1117
             +       +  +D  GWG+  K  ++K EF++EY GE+I ++E   R K  ++  +  F
Sbjct: 568  QRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGK-VYDKYMCSF 626

Query: 1118 YMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTF 1177
             +  ++ D ++DA  KGN  RF NHS  PNC      VNGD R+G+FA   I  G EL F
Sbjct: 627  -LFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFF 685

Query: 1178 NY 1179
            +Y
Sbjct: 686  DY 687


>gi|21361095 enhancer of zeste 2 isoform a [Homo sapiens]
          Length = 751

 Score = 94.7 bits (234), Expect = 5e-19
 Identities = 58/182 (31%), Positives = 86/182 (47%), Gaps = 23/182 (12%)

Query: 1011 SEIPKCNCKP---TDENPCGFDSECLNRMLMFECHPQVC----------PAGEFCQNQCF 1057
            +  P C CK    T + PC         + + EC P +C               C+N   
Sbjct: 560  NRFPGCRCKAQCNTKQCPC--------YLAVRECDPDLCLTCGAADHWDSKNVSCKNCSI 611

Query: 1058 TKRQYPETKIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHF 1117
             +       +  +D  GWG+  K  ++K EF++EY GE+I ++E   R K  ++  +  F
Sbjct: 612  QRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGK-VYDKYMCSF 670

Query: 1118 YMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTF 1177
             +  ++ D ++DA  KGN  RF NHS  PNC      VNGD R+G+FA   I  G EL F
Sbjct: 671  -LFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFF 729

Query: 1178 NY 1179
            +Y
Sbjct: 730  DY 731


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 90.9 bits (224), Expect = 8e-18
 Identities = 50/137 (36%), Positives = 69/137 (50%), Gaps = 1/137 (0%)

Query: 1066 KIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKD 1125
            K  K+    WGL A   I   E V EYVG+ I +     R K   +  I   YM  +D D
Sbjct: 1787 KFCKSHIHDWGLFAMEPIAADEMVIEYVGQNIRQVIADMREKRYEDEGIGSSYMFRVDHD 1846

Query: 1126 RIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLG 1185
             IIDA   GN++RF+NHSC PNC     TV    ++ +++   I    E+T++Y    + 
Sbjct: 1847 TIIDATKCGNFARFINHSCNPNCYAKVITVESQKKIVIYSKQHINVNEEITYDYKFP-IE 1905

Query: 1186 NEKTVCRCGASNCSGFL 1202
            + K  C CG+ NC G L
Sbjct: 1906 DVKIPCLCGSENCRGTL 1922



 Score = 32.7 bits (73), Expect = 2.4
 Identities = 33/133 (24%), Positives = 55/133 (41%), Gaps = 3/133 (2%)

Query: 515  EEDSGNVNGKKRNHTKRIQDPTEDAEAEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKA 574
            E DSG    +K + ++  +   E+ EAE+   +    D  S   RD   +    T+  +A
Sbjct: 1028 ELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDS-DDRDESENDDEDTALSEA 1086

Query: 575  MEAASSLKSQAATKNLSDACKPLKKRNRASTAASSALGFSKSSSPSASLTENEVSDSPGD 634
             E       +  T  +S      +  + + ++ SS    S  SSPS+S  E EV     +
Sbjct: 1087 SEKDEGDSDEEET--VSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEE 1144

Query: 635  EPSESPYESADET 647
            E  E     A+E+
Sbjct: 1145 EEEEEEEMVAEES 1157


>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [Homo
            sapiens]
          Length = 3969

 Score = 89.0 bits (219), Expect = 3e-17
 Identities = 50/130 (38%), Positives = 68/130 (52%), Gaps = 2/130 (1%)

Query: 1074 GWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPK 1133
            G GL  KR+I  GE V EY G +I   +   R K+     I   YM  ID   ++DA   
Sbjct: 3840 GRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIG-CYMFRIDDSEVVDATMH 3898

Query: 1134 GNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCL-GNEKTVCR 1192
            GN +RF+NHSC+PNC +    ++G   + +FA+  I  G ELT++Y       + K  C 
Sbjct: 3899 GNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPIEDASNKLPCN 3958

Query: 1193 CGASNCSGFL 1202
            CGA  C  FL
Sbjct: 3959 CGAKKCRKFL 3968



 Score = 36.6 bits (83), Expect = 0.17
 Identities = 30/112 (26%), Positives = 44/112 (39%), Gaps = 8/112 (7%)

Query: 669  VCQLCEKPGSL--LLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVCKESKTD 726
            VC LC   G +  + C+  CC  FH  CL  + RP      + C      C VC      
Sbjct: 1433 VCFLCASSGHVEFVYCQ-VCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQA 1491

Query: 727  VKRCV-VTQCGKFYHEACV-KKYPL-TVFESRGFRCPLHSCVSCHASNPSNP 775
             K+ +   +C   YH  C+   YP     + + + C    CV C +   + P
Sbjct: 1492 TKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICT--KCVRCKSCGSTTP 1541



 Score = 33.5 bits (75), Expect = 1.4
 Identities = 21/75 (28%), Positives = 30/75 (40%), Gaps = 10/75 (13%)

Query: 1242 CFRCGDGGQLVLCDRKFCTKAYHLSCLGLGKRP----FGKWEC-PWHHCDVCGKPSTSF- 1295
            CF C   G +     + C + +H  CL   +RP       W C     C VCG+   +  
Sbjct: 1434 CFLCASSGHVEFVYCQVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQATK 1493

Query: 1296 ----CHLCPNSFCKE 1306
                C+ C NS+  E
Sbjct: 1494 QLLECNKCRNSYHPE 1508


>gi|4507321 suppressor of variegation 3-9 homolog 1 [Homo sapiens]
          Length = 412

 Score = 88.6 bits (218), Expect = 4e-17
 Identities = 63/194 (32%), Positives = 89/194 (45%), Gaps = 30/194 (15%)

Query: 1038 MFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTD-GKGWGLVAKRDIRKGEFVNEYVGEL 1096
            ++EC+ + C  G  C N+   K    +  I +TD G+GWG+     IRK  FV EYVGE+
Sbjct: 219  IYECNSR-CRCGYDCPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEI 277

Query: 1097 IDEEECMARIKHAHENDITHFYMLTIDKD-RIIDAGPKGNYSRFMNHSCQPNCETLKWTV 1155
            I  EE   R +       T+ + L   +D   +DA   GN S F+NHSC PN +     +
Sbjct: 278  ITSEEAERRGQIYDRQGATYLFDLDYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVFI 337

Query: 1156 NG----DTRVGLFAVCDIPAGTELTFNYNL--DCLGNEKT-------------------- 1189
            +       R+  FA   I AG ELTF+YN+  D +  E T                    
Sbjct: 338  DNLDERLPRIAFFATRTIRAGEELTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVR 397

Query: 1190 -VCRCGASNCSGFL 1202
              C+CG  +C  +L
Sbjct: 398  IECKCGTESCRKYL 411


>gi|194306650 SET domain and mariner transposase fusion [Homo sapiens]
          Length = 684

 Score = 83.2 bits (204), Expect = 2e-15
 Identities = 64/217 (29%), Positives = 98/217 (45%), Gaps = 35/217 (16%)

Query: 1016 CNCKPTDENPCGFDSECLNRM--------LMFECHPQVCPAGEFCQNQCFTKRQYPETKI 1067
            C+C    EN    D+ CL  +         +FEC+  +C   + C+N+   K      ++
Sbjct: 87   CSCLRHGENYD--DNSCLRDIGSGGKYAEPVFECNV-LCRCSDHCRNRVVQKGLQFHFQV 143

Query: 1068 IKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDK--- 1124
             KT  KGWGL     I KG FV EY GE++   E   RI    ++D    Y++ I +   
Sbjct: 144  FKTHKKGWGLRTLEFIPKGRFVCEYAGEVLGFSEVQRRIHLQTKSDSN--YIIAIREHVY 201

Query: 1125 -----DRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDT-RVGLFAVCDIPAGTELTFN 1178
                 +  +D    GN  RF+NHSC+PN   +   ++    ++ LFA  DI    EL+++
Sbjct: 202  NGQVMETFVDPTYIGNIGRFLNHSCEPNLLMIPVRIDSMVPKLALFAAKDIVPEEELSYD 261

Query: 1179 YNLDCL-------------GNEKTVCRCGASNCSGFL 1202
            Y+   L             G  +  C CGA +C+ FL
Sbjct: 262  YSGRYLNLTVSEDKERLDHGKLRKPCYCGAKSCTAFL 298


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 82.8 bits (203), Expect = 2e-15
 Identities = 46/127 (36%), Positives = 68/127 (53%), Gaps = 2/127 (1%)

Query: 1073 KGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGP 1132
            +G GL A +D+ K   V EY+G +I  E    R K  +E      YM  I+ + +IDA  
Sbjct: 5407 QGLGLYAAKDLEKHTMVIEYIGTIIRNEVANRREK-IYEEQNRGIYMFRINNEHVIDATL 5465

Query: 1133 KGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNE-KTVC 1191
             G  +R++NHSC PNC     T + + ++ + +   IP G ELT++Y  D   ++ K  C
Sbjct: 5466 TGGPARYINHSCAPNCVAEVVTFDKEDKIIIISSRRIPKGEELTYDYQFDFEDDQHKIPC 5525

Query: 1192 RCGASNC 1198
             CGA NC
Sbjct: 5526 HCGAWNC 5532



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 35/114 (30%), Positives = 48/114 (42%), Gaps = 13/114 (11%)

Query: 661 GVTAKKEYVCQLCEKPGSL---LLCEGPCCGAFHLACL--GLSRRPEGRFTCSECASGIH 715
           G    +E  C +CE PG L     C   C   +H ACL   L+ R    + C EC     
Sbjct: 220 GAAYLEEARCAVCEGPGELCDLFFCTS-CGHHYHGACLDTALTARKRAGWQCPECKV--- 275

Query: 716 SCFVCKESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHA 769
            C  C++   D K  V   C K YH  C+K  P+    +  ++C   +C  C A
Sbjct: 276 -CQACRKPGNDSKMLVCETCDKGYHTFCLKP-PMEELPAHSWKC--KACRVCRA 325



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 54/214 (25%), Positives = 72/214 (33%), Gaps = 28/214 (13%)

Query: 670 CQLCEKPGSLLLCEGPCCGA-FHLACLGLS----RRPEGRFTCSECASGIH-----SCFV 719
           C  C + G+ + C  P C   +H  C   S         +  C E + G        C V
Sbjct: 172 CSHCTRLGASIPCRSPGCPRLYHFPCATASGSFLSMKTLQLLCPEHSEGAAYLEEARCAV 231

Query: 720 CKESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASN-PSNPRPS 778
           C+           T CG  YH AC+    LT  +  G++CP   C  C A   P N    
Sbjct: 232 CEGPGELCDLFFCTSCGHHYHGACLDT-ALTARKRAGWQCP--ECKVCQACRKPGND--- 285

Query: 779 KGKMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHV--------N 830
             KM+ C  C   YH+   CL      + ++S  C A    R      A +        N
Sbjct: 286 -SKMLVCETCDKGYHT--FCLKPPMEELPAHSWKCKACRVCRACGAGSAELNPNSEWFEN 342

Query: 831 VSWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPD 864
            S C  C K        S      P C     P+
Sbjct: 343 YSLCHRCHKAQGGQTIRSVAEQHTPVCSRFSPPE 376



 Score = 48.1 bits (113), Expect = 6e-05
 Identities = 61/275 (22%), Positives = 97/275 (35%), Gaps = 27/275 (9%)

Query: 536  TEDAEAEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACK 595
            T+ + A D    RL TD         + D     S  KA       +S  A   +     
Sbjct: 1246 TDVSPARDEGSLRLCTDSLPETDDSLLCDAGTAISGGKAEGEKGRRRSSPARSRIKQGRS 1305

Query: 596  ---PLKKRNRASTAASSALGFSKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVS 652
               P ++R R         G ++  S ++S+    V+D     PS+   E  D+T     
Sbjct: 1306 SSFPGRRRPRGGAHGGRGRGRARLKSTASSIETLVVADIDSS-PSKEEEEEDDDTMQNTV 1364

Query: 653  VSSKKSERGVTAKKEYVCQLCEK-----PGSLLLCEGPCCGAFHLACLGLSRRPE---GR 704
            V    +++ V  +   +C +C        G LL C   C   +H  C+            
Sbjct: 1365 VLFSNTDKFVLMQD--MCVVCGSFGRGAEGHLLACS-QCSQCYHPYCVNSKITKVMLLKG 1421

Query: 705  FTCSECASGIHSCFVCKESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCP-LHS 763
            + C EC      C VC ++    +  +   C   YH  C+   PL      G++C    S
Sbjct: 1422 WRCVECIV----CEVCGQASDPSRLLLCDDCDISYHTYCLDP-PLLTVPKGGWKCKWCVS 1476

Query: 764  CVSCHASNP------SNPRPSKGKMMRCVRCPVAY 792
            C+ C A++P       N     G     V CP+ +
Sbjct: 1477 CMQCGAASPGFHCEWQNSYTHCGPCASLVTCPICH 1511



 Score = 40.0 bits (92), Expect = 0.015
 Identities = 29/108 (26%), Positives = 37/108 (34%), Gaps = 22/108 (20%)

Query: 788 CPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHH---------AHVNVSW----- 833
           CP           A C+V      +C   F    G  +H         A     W     
Sbjct: 214 CPEHSEGAAYLEEARCAVCEGPGELCDLFFCTSCGHHYHGACLDTALTARKRAGWQCPEC 273

Query: 834 --CFVCSKGGS---LLCCESCPAAFHPDCLN---IEMPDGSWFCNDCR 873
             C  C K G+   +L CE+C   +H  CL     E+P  SW C  CR
Sbjct: 274 KVCQACRKPGNDSKMLVCETCDKGYHTFCLKPPMEELPAHSWKCKACR 321



 Score = 31.2 bits (69), Expect = 7.1
 Identities = 15/48 (31%), Positives = 20/48 (41%), Gaps = 9/48 (18%)

Query: 834  CFVCSK-----GGSLLCCESCPAAFHPDCLNIEMPD----GSWFCNDC 872
            C VC        G LL C  C   +HP C+N ++        W C +C
Sbjct: 1380 CVVCGSFGRGAEGHLLACSQCSQCYHPYCVNSKITKVMLLKGWRCVEC 1427


>gi|55741677 SET domain containing 1A [Homo sapiens]
          Length = 1707

 Score = 82.4 bits (202), Expect = 3e-15
 Identities = 45/128 (35%), Positives = 63/128 (49%), Gaps = 1/128 (0%)

Query: 1075 WGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKG 1134
            WGL A   I   E V EYVG+ I +     R K   +  I   Y+  +D D IIDA   G
Sbjct: 1580 WGLFAMEPIAADEMVIEYVGQNIRQMVADMREKRYVQEGIGSSYLFRVDHDTIIDATKCG 1639

Query: 1135 NYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCG 1194
            N +RF+NH C PNC     T+    ++ +++   I    E+T++Y    L + K  C CG
Sbjct: 1640 NLARFINHCCTPNCYAKVITIESQKKIVIYSKQPIGVDEEITYDYKFP-LEDNKIPCLCG 1698

Query: 1195 ASNCSGFL 1202
              +C G L
Sbjct: 1699 TESCRGSL 1706



 Score = 34.7 bits (78), Expect = 0.64
 Identities = 38/150 (25%), Positives = 60/150 (40%), Gaps = 11/150 (7%)

Query: 511  PVQAEEDSGNVNGKKRNHTKRIQDPTEDAEAEDTPRKRLRTDKHSLRKRDT-----ITDK 565
            P + +E+ G   GK R  +  +    E+A  E +  K    D+      D       T K
Sbjct: 941  PPKRDEERGKTQGKHRK-SFALDSEGEEASQESSSEKDEEDDEEDEEDEDREEAVDTTKK 999

Query: 566  TARTSSYKAMEAASSLKSQAATKNLSDACKPLKKRNRASTAASSALGFSKSSSPSASLTE 625
                S  +  E+ SS K      +  +        + +S+++SS+   S SSS S+S + 
Sbjct: 1000 ETEVSDGEDEESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSS---SSSSSSSSSSSS 1056

Query: 626  NEVSDSPGDEPSESP--YESADETQTEVSV 653
            +  S S  +E  E P    SA     EV V
Sbjct: 1057 SSESSSEDEEEEERPAALPSASPPPREVPV 1086


>gi|156142199 euchromatic histone-lysine N-methyltransferase 2 isoform
            b [Homo sapiens]
          Length = 1176

 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 72/245 (29%), Positives = 110/245 (44%), Gaps = 40/245 (16%)

Query: 983  ESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKPTDENP----------CGFDSEC 1032
            + E  P  YK+I  N     + I   +I+ +  C C     +           C +D + 
Sbjct: 908  DGEPCPEDYKYISENCETSTMNI-DRNITHLQHCTCVDDCSSSNCLCGQLSIRCWYDKDG 966

Query: 1033 --------LNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAKRDIR 1084
                    +   L+FEC+ Q C     C+N+          ++ +T   GWG+ A + I 
Sbjct: 967  RLLQEFNKIEPPLIFECN-QACSCWRNCKNRVVQSGIKVRLQLYRTAKMGWGVRALQTIP 1025

Query: 1085 KGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTID-KD---RIIDAGPKGNYSRFM 1140
            +G F+ EYVGELI + E   R     E+D    Y+  +D KD     IDA   GN SRF+
Sbjct: 1026 QGTFICEYVGELISDAEADVR-----EDD---SYLFDLDNKDGEVYCIDARYYGNISRFI 1077

Query: 1141 NHSCQPNCETLK-WTVNGD---TRVGLFAVCDIPAGTELTFNYNLDCLGNEKT---VCRC 1193
            NH C PN   ++ + ++ D    R+  F+  DI  G EL F+Y  D   + K+    C+C
Sbjct: 1078 NHLCDPNIIPVRVFMLHQDLRFPRIAFFSSRDIRTGEELGFDYG-DRFWDIKSKYFTCQC 1136

Query: 1194 GASNC 1198
            G+  C
Sbjct: 1137 GSEKC 1141


>gi|156142197 euchromatic histone-lysine N-methyltransferase 2 isoform
            a [Homo sapiens]
          Length = 1210

 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 72/245 (29%), Positives = 110/245 (44%), Gaps = 40/245 (16%)

Query: 983  ESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKPTDENP----------CGFDSEC 1032
            + E  P  YK+I  N     + I   +I+ +  C C     +           C +D + 
Sbjct: 942  DGEPCPEDYKYISENCETSTMNI-DRNITHLQHCTCVDDCSSSNCLCGQLSIRCWYDKDG 1000

Query: 1033 --------LNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAKRDIR 1084
                    +   L+FEC+ Q C     C+N+          ++ +T   GWG+ A + I 
Sbjct: 1001 RLLQEFNKIEPPLIFECN-QACSCWRNCKNRVVQSGIKVRLQLYRTAKMGWGVRALQTIP 1059

Query: 1085 KGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTID-KD---RIIDAGPKGNYSRFM 1140
            +G F+ EYVGELI + E   R     E+D    Y+  +D KD     IDA   GN SRF+
Sbjct: 1060 QGTFICEYVGELISDAEADVR-----EDD---SYLFDLDNKDGEVYCIDARYYGNISRFI 1111

Query: 1141 NHSCQPNCETLK-WTVNGD---TRVGLFAVCDIPAGTELTFNYNLDCLGNEKT---VCRC 1193
            NH C PN   ++ + ++ D    R+  F+  DI  G EL F+Y  D   + K+    C+C
Sbjct: 1112 NHLCDPNIIPVRVFMLHQDLRFPRIAFFSSRDIRTGEELGFDYG-DRFWDIKSKYFTCQC 1170

Query: 1194 GASNC 1198
            G+  C
Sbjct: 1171 GSEKC 1175


>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
            sapiens]
          Length = 2715

 Score = 79.0 bits (193), Expect = 3e-14
 Identities = 50/130 (38%), Positives = 65/130 (50%), Gaps = 2/130 (1%)

Query: 1074 GWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPK 1133
            G GL  KR+I  GE V EY G +I       R K      I   YM  +D   ++DA   
Sbjct: 2586 GRGLFCKRNIDAGEMVIEYSGIVIRSVLTDKREKFYDGKGIG-CYMFRMDDFDVVDATMH 2644

Query: 1134 GNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCL-GNEKTVCR 1192
            GN +RF+NHSC+PNC +    V G   + +FA+  I  G ELT++Y       + K  C 
Sbjct: 2645 GNAARFINHSCEPNCFSRVIHVEGQKHIVIFALRRILRGEELTYDYKFPIEDASNKLPCN 2704

Query: 1193 CGASNCSGFL 1202
            CGA  C  FL
Sbjct: 2705 CGAKRCRRFL 2714



 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 41/142 (28%), Positives = 52/142 (36%), Gaps = 18/142 (12%)

Query: 669  VCQLCEKPG--SLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVCKESKTD 726
            VC LC   G   L+ C+  CC  FH  CL  + RP  +   + C      C VC      
Sbjct: 1203 VCLLCASKGLHELVFCQ-VCCDPFHPFCLEEAERPLPQHHDTWCCRRCKFCHVCGRKGRG 1261

Query: 727  VKRCV-VTQCGKFYHEACV-KKYPLTVFESRGFRCPLH-SCVSCHASNPSNPRPSK---- 779
             K  +   +C   YH AC+   YP     +R  R   H  C +C         P K    
Sbjct: 1262 SKHLLECERCRHAYHPACLGPSYP-----TRATRKRRHWICSACVRCKSCGATPGKNWDV 1316

Query: 780  ---GKMMRCVRCPVAYHSGDAC 798
               G    C RC   Y  G+ C
Sbjct: 1317 EWSGDYSLCPRCTQLYEKGNYC 1338



 Score = 35.0 bits (79), Expect = 0.49
 Identities = 18/50 (36%), Positives = 23/50 (46%), Gaps = 10/50 (20%)

Query: 833  WCFVCSKGGS----LLCCESCPAAFHPDCLNIEMPDGS------WFCNDC 872
            +C VC + G     LL CE C  A+HP CL    P  +      W C+ C
Sbjct: 1251 FCHVCGRKGRGSKHLLECERCRHAYHPACLGPSYPTRATRKRRHWICSAC 1300



 Score = 32.0 bits (71), Expect = 4.2
 Identities = 20/60 (33%), Positives = 26/60 (43%), Gaps = 10/60 (16%)

Query: 1242 CFRCGDGG--QLVLCDRKFCTKAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLC 1299
            C  C   G  +LV C  + C   +H  CL   +RP      P HH   C +    FCH+C
Sbjct: 1204 CLLCASKGLHELVFC--QVCCDPFHPFCLEEAERPL-----PQHHDTWCCR-RCKFCHVC 1255


>gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo
            sapiens]
          Length = 4911

 Score = 78.6 bits (192), Expect = 4e-14
 Identities = 46/127 (36%), Positives = 65/127 (51%), Gaps = 2/127 (1%)

Query: 1073 KGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGP 1132
            +G GL A RDI K   V EY+G +I   E   R +  +E+     YM  +D D +IDA  
Sbjct: 4781 QGLGLYAARDIEKHTMVIEYIGTII-RNEVANRKEKLYESQNRGVYMFRMDNDHVIDATL 4839

Query: 1133 KGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNE-KTVC 1191
             G  +R++NHSC PNC     T     ++ + +   I  G EL ++Y  D   ++ K  C
Sbjct: 4840 TGGPARYINHSCAPNCVAEVVTFERGHKIIISSSRRIQKGEELCYDYKFDFEDDQHKIPC 4899

Query: 1192 RCGASNC 1198
             CGA NC
Sbjct: 4900 HCGAVNC 4906



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 40/139 (28%), Positives = 58/139 (41%), Gaps = 18/139 (12%)

Query: 664 AKKEYVCQLCEKPGSLL---LCEGPCCGAFHLACLGLSRRPEGR--FTCSECASGIHSCF 718
           +K++  C +C+ PG LL    C   C   +H  CL ++  P  R  + C EC      C 
Sbjct: 338 SKEDANCAVCDSPGDLLDQFFCT-TCGQHYHGMCLDIAVTPLKRAGWQCPECKV----CQ 392

Query: 719 VCKESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCP-LHSCVSCHASNPSNPRP 777
            CK+S  D K  V   C K YH  C++    +V  + G++C     C+ C        R 
Sbjct: 393 NCKQSGEDSKMLVCDTCDKGYHTFCLQPVMKSV-PTNGWKCKNCRICIEC------GTRS 445

Query: 778 SKGKMMRCVRCPVAYHSGD 796
           S      C+ C   Y   D
Sbjct: 446 SSQWHHNCLICDNCYQQQD 464



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 42/185 (22%), Positives = 64/185 (34%), Gaps = 35/185 (18%)

Query: 717  CFVCKE--SKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSN 774
            C VC       + +    +QCG+ YH  CV      V  S+G+RC    C  C A   + 
Sbjct: 960  CVVCGSFGQGAEGRLLACSQCGQCYHPYCVSIKITKVVLSKGWRC--LECTVCEACGKAT 1017

Query: 775  PRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIASNS------IICTAHFTARKGKRHHAH 828
                 G+++ C  C ++YH+   CL      +          + C        G R    
Sbjct: 1018 ---DPGRLLLCDDCDISYHT--YCLDPPLQTVPKGGWKCKWCVWCRHCGATSAGLRCEWQ 1072

Query: 829  VNVSWCFVCSKGGS-------------LLCCESCPAAFHPDCLNI-------EMPDGSWF 868
             N + C  C+   S             +L C  C    H  C N+        + D  + 
Sbjct: 1073 NNYTQCAPCASLSSCPVCYRNYREEDLILQCRQCDRWMHAVCQNLNTEEEVENVADIGFD 1132

Query: 869  CNDCR 873
            C+ CR
Sbjct: 1133 CSMCR 1137



 Score = 38.5 bits (88), Expect = 0.044
 Identities = 27/86 (31%), Positives = 38/86 (44%), Gaps = 5/86 (5%)

Query: 1240 DECFRCGDGGQLVLCDRKFCTKAYHLSCLG--LGKRPFGKWECPW-HHCDVCGKPSTSFC 1296
            + C +  D G+L+LCD   C  +YH  CL   L   P G W+C W   C  CG  S    
Sbjct: 1011 EACGKATDPGRLLLCDD--CDISYHTYCLDPPLQTVPKGGWKCKWCVWCRHCGATSAGLR 1068

Query: 1297 HLCPNSFCKEHQDGTAFSCTPDGRSY 1322
                N++ +     +  SC    R+Y
Sbjct: 1069 CEWQNNYTQCAPCASLSSCPVCYRNY 1094



 Score = 34.3 bits (77), Expect = 0.84
 Identities = 38/166 (22%), Positives = 52/166 (31%), Gaps = 23/166 (13%)

Query: 717 CFVCKESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPR 776
           C  CK     +K C   +C + YH  C          +  F+   H  + C       P 
Sbjct: 285 CAFCKHLGATIK-CCEEKCTQMYHYPCAAG-------AGTFQDFSHIFLLCPEHIDQAPE 336

Query: 777 PSKGKMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNVSWCFV 836
            SK        C V    GD      C+    +             KR  A      C V
Sbjct: 337 RSKED----ANCAVCDSPGDLLDQFFCTTCGQHYHGMCLDIAVTPLKR--AGWQCPECKV 390

Query: 837 CS------KGGSLLCCESCPAAFHPDCLNIEM---PDGSWFCNDCR 873
           C       +   +L C++C   +H  CL   M   P   W C +CR
Sbjct: 391 CQNCKQSGEDSKMLVCDTCDKGYHTFCLQPVMKSVPTNGWKCKNCR 436



 Score = 33.1 bits (74), Expect = 1.9
 Identities = 22/60 (36%), Positives = 28/60 (46%), Gaps = 10/60 (16%)

Query: 1235 KRQSED-ECFRCGDGGQLVLCDRKFCTKA---YHLSCLGLGKRPFGK--WECPWHHCDVC 1288
            +R  ED  C  C   G L+  D+ FCT     YH  CL +   P  +  W+CP   C VC
Sbjct: 336  ERSKEDANCAVCDSPGDLL--DQFFCTTCGQHYHGMCLDIAVTPLKRAGWQCP--ECKVC 391



 Score = 33.1 bits (74), Expect = 1.9
 Identities = 22/88 (25%), Positives = 33/88 (37%), Gaps = 23/88 (26%)

Query: 1242 CFRCGDGGQLVLCDRKFCTKAYHLSCLG--LGKRPFGKWECP---------------WH- 1283
            C + G+  ++++CD   C K YH  CL   +   P   W+C                WH 
Sbjct: 394  CKQSGEDSKMLVCDT--CDKGYHTFCLQPVMKSVPTNGWKCKNCRICIECGTRSSSQWHH 451

Query: 1284 ---HCDVCGKPSTSFCHLCPNSFCKEHQ 1308
                CD C +   + C  C   +  E Q
Sbjct: 452  NCLICDNCYQQQDNLCPFCGKCYHPELQ 479


>gi|224465233 euchromatic histone-lysine N-methyltransferase 1 isoform
            1 [Homo sapiens]
          Length = 1298

 Score = 78.2 bits (191), Expect = 5e-14
 Identities = 74/264 (28%), Positives = 114/264 (43%), Gaps = 39/264 (14%)

Query: 983  ESERKPPPYKHIKVNKPYGKVQI--------YTADISEIPKCNCKPTDENP-CGFDSE-- 1031
            +SE  P  YK++  N     + I        Y   I +    NC     +  C +D +  
Sbjct: 1030 DSEPCPSNYKYVSQNCVTSPMNIDRNITHLQYCVCIDDCSSSNCMCGQLSMRCWYDKDGR 1089

Query: 1032 ------CLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAKRDIRK 1085
                       L+FEC+   C     C+N+          ++ +T   GWG+ + +DI  
Sbjct: 1090 LLPEFNMAEPPLIFECN-HACSCWRNCRNRVVQNGLRARLQLYRTRDMGWGVRSLQDIPP 1148

Query: 1086 GEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKD---RIIDAGPKGNYSRFMNH 1142
            G FV EYVGELI + E   R + ++  D+        +KD     IDA   GN SRF+NH
Sbjct: 1149 GTFVCEYVGELISDSEADVREEDSYLFDLD-------NKDGEVYCIDARFYGNVSRFINH 1201

Query: 1143 SCQPNCETLK-WTVNGD---TRVGLFAVCDIPAGTELTFNYN---LDCLGNEKTVCRCGA 1195
             C+PN   ++ +  + D    R+  F+   I AG +L F+Y     D  G +   CRCG+
Sbjct: 1202 HCEPNLVPVRVFMAHQDLRFPRIAFFSTRLIEAGEQLGFDYGERFWDIKG-KLFSCRCGS 1260

Query: 1196 SNC---SGFLGDRPKTSTTLSSEE 1216
              C   S  L  R  ++   + E+
Sbjct: 1261 PKCRHSSAALAQRQASAAQEAQED 1284


>gi|4504191 mutS homolog 6 [Homo sapiens]
          Length = 1360

 Score = 72.0 bits (175), Expect = 4e-12
 Identities = 48/166 (28%), Positives = 81/166 (48%), Gaps = 12/166 (7%)

Query: 220 YNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEK 279
           ++ GDLVW+K+ GYPWWPC+V   P   ++ + KG  KS R  HVQFF D+P R W+ ++
Sbjct: 90  FSPGDLVWAKMEGYPWWPCLVYNHPFDGTFIREKG--KSVR-VHVQFFDDSPTRGWVSKR 146

Query: 280 SLVAFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEMGIVQAEEAA----SM 335
            L  + G        +E+ K     + K ++L+ +     A  +  I + E A     S 
Sbjct: 147 LLKPYTGSKS-----KEAQKGGHFYSAKPEILRAMQRADEALNKDKIKRLELAVCDEPSE 201

Query: 336 SVEERKAKFTFLYVGDQLHLNPQVAKEAGIAAESLGEMAESSGVSE 381
             EE + +    YV D+   + ++  E  +  ++ G    S  + +
Sbjct: 202 PEEEEEMEVGTTYVTDKSEEDNEIESEEEVQPKTQGSRRSSRQIKK 247



 Score = 35.0 bits (79), Expect = 0.49
 Identities = 25/124 (20%), Positives = 47/124 (37%), Gaps = 8/124 (6%)

Query: 882  DIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPY-- 939
            D++W K+  Y WWP  V +       I++    +     FF  S    W  +  + PY  
Sbjct: 94   DLVWAKMEGYPWWPCLVYNHPFDGTFIREKGKSVRVHVQFFDDSPTRGWVSKRLLKPYTG 153

Query: 940  ---MEGDRGSRYQGVRGIGRVFKNALQEAEARFREIKLQREARETQESERKPPPYKHIKV 996
                E  +G  +   +        A+Q A+    + K++R      +   +P   + ++V
Sbjct: 154  SKSKEAQKGGHFYSAK---PEILRAMQRADEALNKDKIKRLELAVCDEPSEPEEEEEMEV 210

Query: 997  NKPY 1000
               Y
Sbjct: 211  GTTY 214


>gi|94721344 zinc finger, CW type with PWWP domain 1 [Homo sapiens]
          Length = 648

 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 50/193 (25%), Positives = 80/193 (41%), Gaps = 19/193 (9%)

Query: 210 TGRDKD-HLLKYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKS-ARQYHVQFF 267
           TG + D     Y  G ++W+K  GYPWWP M+ +DP L  Y        S   +YHV FF
Sbjct: 304 TGLESDVAYASYIPGSIIWAKQYGYPWWPGMIESDPDLGEYFLFTSHLDSLPSKYHVTFF 363

Query: 268 GDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQAPTKAEKIKLLKPISGKLRAQWEMGIV 327
           G+   RAWI    L        F++L  E           + ++K        +  + ++
Sbjct: 364 GETVSRAWIPVNML------KNFQELSLE-----------LSVMKKRRNDCSQKLGVALM 406

Query: 328 QAEEAASMSVEERKAKFTFLYVGDQLHLNPQVAKEAGIAAESLGEMAESSGVSEEAAENP 387
            A+EA  +S++ER   F F    +  + N +          S G   E     EE  +  
Sbjct: 407 MAQEAEQISIQERVNLFGFWSRFNGSNSNGERKDLQLSGLNSPGSCLEKKEKEEELEKEE 466

Query: 388 KSVREECIPMKRR 400
               +  +P+++R
Sbjct: 467 GEKTDPILPIRKR 479


>gi|24308089 chromodomain helicase DNA binding protein 5 [Homo
            sapiens]
          Length = 1954

 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 46/143 (32%), Positives = 66/143 (46%), Gaps = 17/143 (11%)

Query: 1218 GKKTKKKTRRRRAK-GEG-KRQSEDECFRCGDGGQLVLCDRKFCTKAYHLSCLG--LGKR 1273
            GKK+K++ +++R   G+G +   +D C  C  GG+++LCD   C +AYHL CL   L K 
Sbjct: 320  GKKSKRRRKKKRIDDGDGYETDHQDYCEVCQQGGEIILCDT--CPRAYHLVCLDPELEKA 377

Query: 1274 PFGKWECPWHHCDVCG---KPSTSFCHLCPNSFCKEHQDGTAFS--CTPDGRSYCCEHDL 1328
            P GKW CP  HC+  G   +P             +E  D   F   C   G   CC+   
Sbjct: 378  PEGKWSCP--HCEKEGIQWEPKDDDDEEEEGGCEEEEDDHMEFCRVCKDGGELLCCDACP 435

Query: 1329 GAASVRSTKTEKPPPEPGKPKGK 1351
             +  +        PP P  P G+
Sbjct: 436  SSYHLHCLN----PPLPEIPNGE 454



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 21/46 (45%), Positives = 31/46 (67%), Gaps = 3/46 (6%)

Query: 830 NVSWCFVCSKGGSLLCCESCPAAFHPDCLN---IEMPDGSWFCNDC 872
           ++ +C VC  GG LLCC++CP+++H  CLN    E+P+G W C  C
Sbjct: 415 HMEFCRVCKDGGELLCCDACPSSYHLHCLNPPLPEIPNGEWLCPRC 460



 Score = 50.8 bits (120), Expect = 9e-06
 Identities = 50/199 (25%), Positives = 77/199 (38%), Gaps = 59/199 (29%)

Query: 629 SDSPGDEPSESPYESAD----ETQTEVSVS-SKKSER-----------GVTAKKEYVCQL 672
           S S  DE  ES ++SA       ++E S +  KKS+R           G     +  C++
Sbjct: 289 SSSEEDEREESDFDSASIHSASVRSECSAALGKKSKRRRKKKRIDDGDGYETDHQDYCEV 348

Query: 673 CEKPGSLLLCEGPCCGAFHLACLG--LSRRPEGRFTCSECA------------------- 711
           C++ G ++LC+  C  A+HL CL   L + PEG+++C  C                    
Sbjct: 349 CQQGGEIILCD-TCPRAYHLVCLDPELEKAPEGKWSCPHCEKEGIQWEPKDDDDEEEEGG 407

Query: 712 ------SGIHSCFVCKESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCV 765
                   +  C VCK+     +      C   YH  C+   PL    +  + CP  +C 
Sbjct: 408 CEEEEDDHMEFCRVCKDGG---ELLCCDACPSSYHLHCLNP-PLPEIPNGEWLCPRCTC- 462

Query: 766 SCHASNPSNPRPSKGKMMR 784
                      P KGK+ R
Sbjct: 463 ----------PPLKGKVQR 471



 Score = 49.3 bits (116), Expect = 3e-05
 Identities = 18/43 (41%), Positives = 28/43 (65%), Gaps = 3/43 (6%)

Query: 833 WCFVCSKGGSLLCCESCPAAFHPDCLNIEM---PDGSWFCNDC 872
           +C VC +GG ++ C++CP A+H  CL+ E+   P+G W C  C
Sbjct: 345 YCEVCQQGGEIILCDTCPRAYHLVCLDPELEKAPEGKWSCPHC 387


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.132    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 59,218,491
Number of Sequences: 37866
Number of extensions: 2997061
Number of successful extensions: 14728
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 164
Number of HSP's successfully gapped in prelim test: 334
Number of HSP's that attempted gapping in prelim test: 12895
Number of HSP's gapped (non-prelim): 1904
length of query: 1365
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1250
effective length of database: 13,892,928
effective search space: 17366160000
effective search space used: 17366160000
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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