Guide to the Human Genome
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Search of human proteins with 14318422

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14318422 keratin 86 [Homo sapiens]
         (486 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo sap...   974   0.0  
gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo sap...   974   0.0  
gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo sap...   974   0.0  
gi|14318422 keratin 86 [Homo sapiens]                                 974   0.0  
gi|169790853 keratin, hair, basic, 1 [Homo sapiens]                   897   0.0  
gi|169790841 keratin 83 [Homo sapiens]                                872   0.0  
gi|4504935 keratin 85 [Homo sapiens]                                  789   0.0  
gi|15431316 keratin, hair, basic, 4 [Homo sapiens]                    544   e-155
gi|27477127 keratin 82 [Homo sapiens]                                 533   e-151
gi|119395754 keratin 5 [Homo sapiens]                                 436   e-122
gi|5031839 keratin 6A [Homo sapiens]                                  427   e-119
gi|155969697 keratin 6C [Homo sapiens]                                425   e-119
gi|153791158 keratin 75 [Homo sapiens]                                424   e-118
gi|119703753 keratin 6B [Homo sapiens]                                423   e-118
gi|4504919 keratin 8 [Homo sapiens]                                   415   e-116
gi|109148552 keratin 3 [Homo sapiens]                                 408   e-114
gi|67782365 keratin 7 [Homo sapiens]                                  407   e-113
gi|109255249 keratin 4 [Homo sapiens]                                 404   e-113
gi|15618995 keratin 71 [Homo sapiens]                                 402   e-112
gi|28173564 keratin 73 [Homo sapiens]                                 396   e-110
gi|119395750 keratin 1 [Homo sapiens]                                 394   e-109
gi|153791670 keratin 76 [Homo sapiens]                                392   e-109
gi|28372503 keratin 72 isoform 1 [Homo sapiens]                       391   e-109
gi|226246663 keratin 72 isoform 1 [Homo sapiens]                      391   e-109
gi|32567786 keratin 6L [Homo sapiens]                                 389   e-108
gi|47132620 keratin 2 [Homo sapiens]                                  381   e-106
gi|148612803 keratin 6 irs4 [Homo sapiens]                            379   e-105
gi|194018511 keratin 77 [Homo sapiens]                                352   3e-97
gi|89357932 keratin 5b [Homo sapiens]                                 346   3e-95
gi|226246665 keratin 72 isoform 2 [Homo sapiens]                      335   5e-92

>gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo
           sapiens]
          Length = 486

 Score =  974 bits (2518), Expect = 0.0
 Identities = 486/486 (100%), Positives = 486/486 (100%)

Query: 1   MTCGSYCGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCG 60
           MTCGSYCGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCG
Sbjct: 1   MTCGSYCGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCG 60

Query: 61  RSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF 120
           RSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF
Sbjct: 61  RSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF 120

Query: 121 IDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASEL 180
           IDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASEL
Sbjct: 121 IDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASEL 180

Query: 181 NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR 240
           NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR
Sbjct: 181 NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR 240

Query: 241 RLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK 300
           RLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK
Sbjct: 241 RLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK 300

Query: 301 CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA 360
           CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA
Sbjct: 301 CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA 360

Query: 361 LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG 420
           LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG
Sbjct: 361 LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG 420

Query: 421 VGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSARVGVCG 480
           VGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSARVGVCG
Sbjct: 421 VGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSARVGVCG 480

Query: 481 GSCKRC 486
           GSCKRC
Sbjct: 481 GSCKRC 486


>gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo
           sapiens]
          Length = 486

 Score =  974 bits (2518), Expect = 0.0
 Identities = 486/486 (100%), Positives = 486/486 (100%)

Query: 1   MTCGSYCGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCG 60
           MTCGSYCGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCG
Sbjct: 1   MTCGSYCGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCG 60

Query: 61  RSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF 120
           RSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF
Sbjct: 61  RSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF 120

Query: 121 IDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASEL 180
           IDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASEL
Sbjct: 121 IDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASEL 180

Query: 181 NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR 240
           NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR
Sbjct: 181 NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR 240

Query: 241 RLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK 300
           RLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK
Sbjct: 241 RLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK 300

Query: 301 CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA 360
           CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA
Sbjct: 301 CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA 360

Query: 361 LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG 420
           LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG
Sbjct: 361 LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG 420

Query: 421 VGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSARVGVCG 480
           VGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSARVGVCG
Sbjct: 421 VGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSARVGVCG 480

Query: 481 GSCKRC 486
           GSCKRC
Sbjct: 481 GSCKRC 486


>gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo
           sapiens]
          Length = 486

 Score =  974 bits (2518), Expect = 0.0
 Identities = 486/486 (100%), Positives = 486/486 (100%)

Query: 1   MTCGSYCGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCG 60
           MTCGSYCGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCG
Sbjct: 1   MTCGSYCGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCG 60

Query: 61  RSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF 120
           RSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF
Sbjct: 61  RSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF 120

Query: 121 IDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASEL 180
           IDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASEL
Sbjct: 121 IDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASEL 180

Query: 181 NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR 240
           NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR
Sbjct: 181 NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR 240

Query: 241 RLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK 300
           RLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK
Sbjct: 241 RLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK 300

Query: 301 CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA 360
           CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA
Sbjct: 301 CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA 360

Query: 361 LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG 420
           LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG
Sbjct: 361 LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG 420

Query: 421 VGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSARVGVCG 480
           VGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSARVGVCG
Sbjct: 421 VGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSARVGVCG 480

Query: 481 GSCKRC 486
           GSCKRC
Sbjct: 481 GSCKRC 486


>gi|14318422 keratin 86 [Homo sapiens]
          Length = 486

 Score =  974 bits (2518), Expect = 0.0
 Identities = 486/486 (100%), Positives = 486/486 (100%)

Query: 1   MTCGSYCGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCG 60
           MTCGSYCGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCG
Sbjct: 1   MTCGSYCGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCG 60

Query: 61  RSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF 120
           RSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF
Sbjct: 61  RSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF 120

Query: 121 IDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASEL 180
           IDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASEL
Sbjct: 121 IDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASEL 180

Query: 181 NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR 240
           NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR
Sbjct: 181 NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR 240

Query: 241 RLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK 300
           RLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK
Sbjct: 241 RLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK 300

Query: 301 CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA 360
           CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA
Sbjct: 301 CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA 360

Query: 361 LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG 420
           LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG
Sbjct: 361 LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG 420

Query: 421 VGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSARVGVCG 480
           VGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSARVGVCG
Sbjct: 421 VGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSARVGVCG 480

Query: 481 GSCKRC 486
           GSCKRC
Sbjct: 481 GSCKRC 486


>gi|169790853 keratin, hair, basic, 1 [Homo sapiens]
          Length = 505

 Score =  897 bits (2319), Expect = 0.0
 Identities = 457/507 (90%), Positives = 465/507 (91%), Gaps = 23/507 (4%)

Query: 1   MTCGSYCGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCG 60
           MTCGS  GGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCG
Sbjct: 1   MTCGSGFGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCG 60

Query: 61  RSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF 120
           RSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF
Sbjct: 61  RSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF 120

Query: 121 IDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASEL 180
           IDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASEL
Sbjct: 121 IDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASEL 180

Query: 181 NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR 240
           NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR
Sbjct: 181 NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR 240

Query: 241 RLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK 300
           RLYEEEI +LQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK
Sbjct: 241 RLYEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK 300

Query: 301 CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA 360
           CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA
Sbjct: 301 CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA 360

Query: 361 LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG 420
           LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG
Sbjct: 361 LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG 420

Query: 421 VGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAP-------- 472
           +G+VNVCVSSSRGGVVCGDLC S + PV  + V S P N NV V +T  CAP        
Sbjct: 421 IGAVNVCVSSSRGGVVCGDLCVSGSRPVTGS-VCSAPCNGNVAV-STGLCAPCGQLNTTC 478

Query: 473 -------------SARVGVCGGSCKRC 486
                        S  VG CG SC++C
Sbjct: 479 GGGSCGVGSCGISSLGVGSCGSSCRKC 505


>gi|169790841 keratin 83 [Homo sapiens]
          Length = 493

 Score =  872 bits (2253), Expect = 0.0
 Identities = 445/490 (90%), Positives = 456/490 (93%), Gaps = 9/490 (1%)

Query: 1   MTCGSY---CGGRA--FSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFR 55
           MTCG     CG R   FSC+SACGPRP RCCITAAPYRGISCYRGLTGGFGSHSVCGGFR
Sbjct: 1   MTCGFNSIGCGFRPGNFSCVSACGPRPSRCCITAAPYRGISCYRGLTGGFGSHSVCGGFR 60

Query: 56  AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS 115
           AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS
Sbjct: 61  AGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNS 120

Query: 116 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGR 175
           RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLF GYIETLRREAECVEADSGR
Sbjct: 121 RFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFAGYIETLRREAECVEADSGR 180

Query: 176 LASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE 235
           LASELNHVQEVLEGYKKKYEEEV+LRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE
Sbjct: 181 LASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANVEALIQE 240

Query: 236 IDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAES 295
           IDFLRRLYEEEIR+LQSHISDTSVVVKLDNSRDLNMDCI+AEIKAQYDDI TRSRAEAES
Sbjct: 241 IDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRSRAEAES 300

Query: 296 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ 355
           WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ
Sbjct: 301 WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQ 360

Query: 356 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ 415
           QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ
Sbjct: 361 QGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQ 420

Query: 416 RLCEGVGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSAR 475
           RLCEGV +VNVCVSSSRGGVVCGDLC S + PV  + V S P N N+VV +T  C P  +
Sbjct: 421 RLCEGVEAVNVCVSSSRGGVVCGDLCVSGSRPVTGS-VCSAPCNGNLVV-STGLCKPCGQ 478

Query: 476 VGVC--GGSC 483
           +     GGSC
Sbjct: 479 LNTTCGGGSC 488


>gi|4504935 keratin 85 [Homo sapiens]
          Length = 507

 Score =  789 bits (2038), Expect = 0.0
 Identities = 408/492 (82%), Positives = 436/492 (88%), Gaps = 24/492 (4%)

Query: 1   MTCGSY-----CG-GRAFSCISACGPRPG-RCCITAAPYRGISCYRGLTGGFGSHSVC-- 51
           M+C SY     CG  R FS  SA  P+ G RCCI+AAPYRG+SCYRGLTG FGS S+C  
Sbjct: 1   MSCRSYRISSGCGVTRNFSSCSAVAPKTGNRCCISAAPYRGVSCYRGLTG-FGSRSLCNL 59

Query: 52  ---------GGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCV 102
                    GGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCV
Sbjct: 60  GSCGPRIAVGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCV 119

Query: 103 KQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETL 162
           KQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETK QFYQN+ CC+SNLEPLF GYIETL
Sbjct: 120 KQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKWQFYQNQRCCESNLEPLFSGYIETL 179

Query: 163 RREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRK 222
           RREAECVEADSGRLASELNHVQEVLEGYKKKYEEEV+LRATAENEFV LKKDVDCAYLRK
Sbjct: 180 RREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVVLKKDVDCAYLRK 239

Query: 223 SDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQY 282
           SDLEANVEAL++E  FLRRLYEEEIRVLQ+HISDTSV+VK+DNSRDLNMDCIIAEIKAQY
Sbjct: 240 SDLEANVEALVEESSFLRRLYEEEIRVLQAHISDTSVIVKMDNSRDLNMDCIIAEIKAQY 299

Query: 283 DDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQ 342
           DD+ +RSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAE+ENAKCQ
Sbjct: 300 DDVASRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEIENAKCQ 359

Query: 343 NSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIE 402
            +KLEAAVA++EQQGEAALSDARCKLAELEGALQKAKQDMACL++EYQEVMNSKLGLDIE
Sbjct: 360 RAKLEAAVAEAEQQGEAALSDARCKLAELEGALQKAKQDMACLLKEYQEVMNSKLGLDIE 419

Query: 403 IATYRRLLEGEEQRLCEGVGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPS--NS 460
           IATYRRLLEGEE RLCEGVGSVNVCVSSSRGGV CG L  STT      +++S PS    
Sbjct: 420 IATYRRLLEGEEHRLCEGVGSVNVCVSSSRGGVSCGGLSYSTTP---GRQITSGPSAIGG 476

Query: 461 NVVVGTTNACAP 472
           ++ V   ++CAP
Sbjct: 477 SITVVAPDSCAP 488


>gi|15431316 keratin, hair, basic, 4 [Homo sapiens]
          Length = 600

 Score =  544 bits (1402), Expect = e-155
 Identities = 295/477 (61%), Positives = 362/477 (75%), Gaps = 17/477 (3%)

Query: 15  ISACGPRPGRCCIT--AAPYRGISCYRGLTGGFGSHSVCG-GFRAGSC------GRSFGY 65
           I+A G RP  C +   A    G    RG+  G  + S  G GF AGS       G  FGY
Sbjct: 65  IAAVGSRPIHCGVRFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGIGYGFGGPGFGY 124

Query: 66  RSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVR 125
           R GGV  P+ P IT V+VN+SLLTPLNLEIDPNAQ VK++EKEQIK+LN++FA+FIDKVR
Sbjct: 125 RVGGVGVPAAPSITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFASFIDKVR 184

Query: 126 FLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASELNHVQE 185
           FLEQQNKLLETK  F Q ++C +SNLEPLFE YI  LRR+ E + +D  RL +E NH+Q+
Sbjct: 185 FLEQQNKLLETKWSFLQEQKCIRSNLEPLFESYITNLRRQLEVLVSDQARLQAERNHLQD 244

Query: 186 VLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEE 245
           VLEG+KKKYEEEV  RA AENEFVALKKDVD A++ KSDLEANV+ L QEIDFL+ LY E
Sbjct: 245 VLEGFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQEIDFLKTLYME 304

Query: 246 EIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMK 305
           EI++LQSHIS+TSV+VK+DNSRDLN+D IIAE+KAQY+++  RSRA+AE+WY++K EEM+
Sbjct: 305 EIQLLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAEAWYQTKYEEMQ 364

Query: 306 ATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDAR 365
            T  +H + LR  + EINEL R+IQRL AE+E+AK Q +KLEAAVA++EQQGEA LSDA+
Sbjct: 365 VTAGQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQGEATLSDAK 424

Query: 366 CKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEGVGSVN 425
           CKLA+LE ALQ+AKQDMA  + EYQE+MN+KLGLDIEIATYRRLLEGEE RLCEGVG VN
Sbjct: 425 CKLADLECALQQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEESRLCEGVGPVN 484

Query: 426 VCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSARVGVCGGS 482
           + VSSSRGG+VCG        P+V+   S++        G+++ CA S  +  CG S
Sbjct: 485 ISVSSSRGGLVCG------PEPLVAG--STLSRGGVTFSGSSSVCATSGVLASCGPS 533


>gi|27477127 keratin 82 [Homo sapiens]
          Length = 513

 Score =  533 bits (1373), Expect = e-151
 Identities = 299/495 (60%), Positives = 358/495 (72%), Gaps = 20/495 (4%)

Query: 4   GSYCGGRAFSCISACGPRP-GRCCITAAPYRGISCYRGLT--GGFGSHSVCG-GFR---- 55
           GS CG ++FS  SA  PR      ++  P R     RGL   G  GS S+C  GF     
Sbjct: 9   GSRCGSQSFSSYSAVMPRMVTHYAVSKGPCRP-GGGRGLRALGCLGSRSLCNVGFGRPRV 67

Query: 56  AGSCGRS---FGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKS 112
           A  CG +   FGYR G  CGPS  CIT V++NESLL PL LEIDP  Q VK++EKEQIK 
Sbjct: 68  ASRCGGTLPGFGYRLGATCGPSA-CITPVTINESLLVPLALEIDPTVQRVKRDEKEQIKC 126

Query: 113 LNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEAD 172
           LN+RFA+FI+KVRFLEQ+NKLLETK  F Q + CCQ+N+EP+FEGYI  LRR+ +CV  D
Sbjct: 127 LNNRFASFINKVRFLEQKNKLLETKWNFMQQQRCCQTNIEPIFEGYISALRRQLDCVSGD 186

Query: 173 SGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEAL 232
             RL SEL  +Q  LEGYKKKYEEE+SLR   ENEFVALKKDVD A+L K+DLE N EAL
Sbjct: 187 RVRLESELCSLQAALEGYKKKYEEELSLRPCVENEFVALKKDVDTAFLMKADLETNAEAL 246

Query: 233 IQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAE 292
           +QEIDFL+ LYEEEI +LQS IS+TSV+VK+DNSR+L++D IIAEIKAQYDDI +RS+AE
Sbjct: 247 VQEIDFLKSLYEEEICLLQSQISETSVIVKMDNSRELDVDGIIAEIKAQYDDIASRSKAE 306

Query: 293 AESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQ 352
           AE+WY+ + EE++ T   H + LR  K EI E+N++IQRL  E EN K Q  KLE A+A+
Sbjct: 307 AEAWYQCRYEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQETENVKAQRCKLEGAIAE 366

Query: 353 SEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEG 412
           +EQQGEAAL+DA+CKLA LE ALQKAKQDMACL++EYQEVMNSKLGLDIEIATYRRLLEG
Sbjct: 367 AEQQGEAALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRLLEG 426

Query: 413 EEQRLCEGVGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNV-VVGTTNACA 471
           EE RLCEG+G VN+ VSSS+G  +      ST  PV+ST V  + SN    +VGT     
Sbjct: 427 EEHRLCEGIGPVNISVSSSKGAFLYEPCGVST--PVLSTGV--LRSNGGCSIVGTGELYV 482

Query: 472 PSARVGV--CGGSCK 484
           P    G+  CG   K
Sbjct: 483 PCEPQGLLSCGSGRK 497


>gi|119395754 keratin 5 [Homo sapiens]
          Length = 590

 Score =  436 bits (1122), Expect = e-122
 Identities = 246/472 (52%), Positives = 324/472 (68%), Gaps = 29/472 (6%)

Query: 40  GLTGGFGSHSVCGGFRAGSCGRSFGYR-SGGVCGPS-PPC----ITTVSVNESLLTPLNL 93
           G  GG GS    GG   G  G   G    GG  GP  P C    I  V+VN+SLLTPLNL
Sbjct: 96  GFGGGAGSGFGFGGGAGGGFGLGGGAGFGGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNL 155

Query: 94  EIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--ECCQSNL 151
           +IDP+ Q V+ EE+EQIK+LN++FA+FIDKVRFLEQQNK+L+TK    Q +  +  + NL
Sbjct: 156 QIDPSIQRVRTEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNL 215

Query: 152 EPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVAL 211
           EPLFE YI  LRR+ + +  + GRL SEL ++Q+++E +K KYE+E++ R TAENEFV L
Sbjct: 216 EPLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLVEDFKNKYEDEINKRTTAENEFVML 275

Query: 212 KKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNM 271
           KKDVD AY+ K +LEA V+AL+ EI+F++  ++ E+  +Q+H+SDTSVV+ +DN+R+L++
Sbjct: 276 KKDVDAAYMNKVELEAKVDALMDEINFMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLDL 335

Query: 272 DCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQR 331
           D IIAE+KAQY++I  RSR EAESWY++K EE++ T  RHG+ LR TK EI+E+NRMIQR
Sbjct: 336 DSIIAEVKAQYEEIANRSRTEAESWYQTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQR 395

Query: 332 LTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQE 391
           L AE++N K Q + L+ A+A +EQ+GE AL DAR KLAELE ALQKAKQDMA L+REYQE
Sbjct: 396 LRAEIDNVKKQCANLQNAIADAEQRGELALKDARNKLAELEEALQKAKQDMARLLREYQE 455

Query: 392 VMNSKLGLDIEIATYRRLLEGEEQRLC-EGVGSVNVCVSSSR------------------ 432
           +MN+KL LD+EIATYR+LLEGEE RL  EGVG VN+ V +S                   
Sbjct: 456 LMNTKLALDVEIATYRKLLEGEECRLSGEGVGPVNISVVTSSVSSGYGSGSGYGGGLGGG 515

Query: 433 -GGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSAR-VGVCGGS 482
            GG + G L   ++    S+    V     + VG +   A S R +GV  GS
Sbjct: 516 LGGGLGGGLAGGSSGSYYSSSSGGVGLGGGLSVGGSGFSASSGRGLGVGFGS 567


>gi|5031839 keratin 6A [Homo sapiens]
          Length = 564

 Score =  427 bits (1097), Expect = e-119
 Identities = 237/451 (52%), Positives = 312/451 (69%), Gaps = 30/451 (6%)

Query: 4   GSYCGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGRSF 63
           G  CGG  F   S  G    +         G SC   ++GG+GS +  G +  G  G  F
Sbjct: 48  GGACGGAGFGSRSLYGLGGSK----RISIGGGSC--AISGGYGSRAG-GSYGFGGAGSGF 100

Query: 64  GYR---------------SGGVCGPS-PPC----ITTVSVNESLLTPLNLEIDPNAQCVK 103
           G+                +GG  GP  P C    I  V+VN+SLLTPLNL+IDP  Q V+
Sbjct: 101 GFGGGAGIGFGLGGGAGLAGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPTIQRVR 160

Query: 104 QEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--ECCQSNLEPLFEGYIET 161
            EE+EQIK+LN++FA+FIDKVRFLEQQNK+LETK    Q +  +  + NLEPLFE YI  
Sbjct: 161 AEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWTLLQEQGTKTVRQNLEPLFEQYINN 220

Query: 162 LRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLR 221
           LRR+ + +  + GRL SEL  +Q+++E +K KYE+E++ R  AENEFV LKKDVD AY+ 
Sbjct: 221 LRRQLDSIVGERGRLDSELRGMQDLVEDFKNKYEDEINKRTAAENEFVTLKKDVDAAYMN 280

Query: 222 KSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQ 281
           K +L+A  + L  EI+FLR LY+ E+  +Q+HISDTSVV+ +DN+R+L++D IIAE+KAQ
Sbjct: 281 KVELQAKADTLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQ 340

Query: 282 YDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKC 341
           Y++I  RSRAEAESWY++K EE++ T  RHG+ LR TK+EI E+NRMIQRL +E+++ K 
Sbjct: 341 YEEIAQRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKK 400

Query: 342 QNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDI 401
           Q + L+AA+A +EQ+GE AL DA+ KL  LE ALQKAKQD+A L++EYQE+MN KL LD+
Sbjct: 401 QCANLQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDV 460

Query: 402 EIATYRRLLEGEEQRL-CEGVGSVNVCVSSS 431
           EIATYR+LLEGEE RL  EGVG VN+ V  S
Sbjct: 461 EIATYRKLLEGEECRLNGEGVGQVNISVVQS 491


>gi|155969697 keratin 6C [Homo sapiens]
          Length = 564

 Score =  425 bits (1092), Expect = e-119
 Identities = 237/451 (52%), Positives = 312/451 (69%), Gaps = 30/451 (6%)

Query: 4   GSYCGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGRSF 63
           G  CGG  F   S  G    +         G SC   ++GG+GS +  G +  G  G  F
Sbjct: 48  GGACGGAGFGSRSLYGLGGSK----RISIGGGSC--AISGGYGSRAG-GSYGFGGAGSGF 100

Query: 64  GYR---------------SGGVCGPS-PPC----ITTVSVNESLLTPLNLEIDPNAQCVK 103
           G+                +GG  GP  P C    I  V+VN+SLLTPLNL+IDP  Q V+
Sbjct: 101 GFGGGAGIGFGLGGGAGLAGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPAIQRVR 160

Query: 104 QEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--ECCQSNLEPLFEGYIET 161
            EE+EQIK+LN++FA+FIDKVRFLEQQNK+L+TK    Q +  +  + NLEPLFE YI  
Sbjct: 161 AEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINN 220

Query: 162 LRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLR 221
           LRR+ + +  + GRL SEL ++Q+++E  K KYE+E++ R  AENEFV LKKDVD AY+ 
Sbjct: 221 LRRQLDSIVGERGRLDSELRNMQDLVEDLKNKYEDEINKRTAAENEFVTLKKDVDAAYMN 280

Query: 222 KSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQ 281
           K +L+A  + L  EI+FLR LY+ E+  +Q+HISDTSVV+ +DN+R+L++D IIAE+KAQ
Sbjct: 281 KVELQAKADTLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQ 340

Query: 282 YDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKC 341
           Y++I  RSRAEAESWY++K EE++ T  RHG+ LR TK+EI E+NRMIQRL +E+++ K 
Sbjct: 341 YEEIAQRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKK 400

Query: 342 QNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDI 401
           Q + L+AA+A +EQ+GE AL DA+ KL  LE ALQKAKQD+A L++EYQE+MN KL LD+
Sbjct: 401 QCASLQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDV 460

Query: 402 EIATYRRLLEGEEQRL-CEGVGSVNVCVSSS 431
           EIATYR+LLEGEE RL  EGVG VNV V  S
Sbjct: 461 EIATYRKLLEGEECRLNGEGVGQVNVSVVQS 491


>gi|153791158 keratin 75 [Homo sapiens]
          Length = 551

 Score =  424 bits (1089), Expect = e-118
 Identities = 241/463 (52%), Positives = 316/463 (68%), Gaps = 41/463 (8%)

Query: 10  RAFSCISACGPRPGRCCIT-------AAPYRGISCYRGLTGGFGSHSV------------ 50
           R FS  SA  P  GR   +       AA   G+         FGS S+            
Sbjct: 15  RGFSTTSAITPAAGRSRFSSVSVARSAAGSGGLGRISSAGASFGSRSLYNLGGAKRVSIN 74

Query: 51  -CGGF-RAGSCGRS---------FGYRSG---GVCGPS-PPC----ITTVSVNESLLTPL 91
            CG   R+G  GR+         FGY  G   G  GPS P C    I  V+VN+SLLTPL
Sbjct: 75  GCGSSCRSGFGGRASNRFGVNSGFGYGGGVGGGFSGPSFPVCPPGGIQEVTVNQSLLTPL 134

Query: 92  NLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--ECCQS 149
           +L+IDP  Q V+ EE+EQIK+LN++FA+FIDKVRFLEQQNK+LETK    Q +     + 
Sbjct: 135 HLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQGSRTVRQ 194

Query: 150 NLEPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFV 209
           NLEPLF+ Y   LRR+ E +  + GRL +EL ++Q+V+E +K +YE+E++ R  AENEFV
Sbjct: 195 NLEPLFDSYTSELRRQLESITTERGRLEAELRNMQDVVEDFKVRYEDEINKRTAAENEFV 254

Query: 210 ALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDL 269
           ALKKDVD AY+ K +LEA V++L +EI+F+  +++ E+  LQ+ + DTSVV+ +DN+R+L
Sbjct: 255 ALKKDVDAAYMNKVELEAKVKSLPEEINFIHSVFDAELSQLQTQVGDTSVVLSMDNNRNL 314

Query: 270 NMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMI 329
           ++D IIAE+KAQY+DI  RSRAEAESWY++K EE++ T  RHG+ LR TK+EI+E+NRMI
Sbjct: 315 DLDSIIAEVKAQYEDIANRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEISEMNRMI 374

Query: 330 QRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREY 389
           QRL AE+++ K Q S L+ A+A +EQ+GE AL DAR KL +LE ALQKAKQDMA L+REY
Sbjct: 375 QRLRAEIDSVKKQCSSLQTAIADAEQRGELALKDARAKLVDLEEALQKAKQDMARLLREY 434

Query: 390 QEVMNSKLGLDIEIATYRRLLEGEEQRLC-EGVGSVNVCVSSS 431
           QE+MN KL LD+EIATYR+LLEGEE RL  EGV  VN+ V +S
Sbjct: 435 QELMNIKLALDVEIATYRKLLEGEECRLSGEGVSPVNISVVTS 477


>gi|119703753 keratin 6B [Homo sapiens]
          Length = 564

 Score =  423 bits (1088), Expect = e-118
 Identities = 236/451 (52%), Positives = 312/451 (69%), Gaps = 30/451 (6%)

Query: 4   GSYCGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGRSF 63
           G  CGG  F   S  G    +         G SC   ++GG+GS +  G +  G  G  F
Sbjct: 48  GGACGGAGFGSRSLYGLGGSK----RISIGGGSC--AISGGYGSRAG-GSYGFGGAGSGF 100

Query: 64  GYR---------------SGGVCGPS-PPC----ITTVSVNESLLTPLNLEIDPNAQCVK 103
           G+                +GG  GP  P C    I  V+VN+SLLTPLNL+IDP  Q V+
Sbjct: 101 GFGGGAGIGFGLGGGAGLAGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPAIQRVR 160

Query: 104 QEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--ECCQSNLEPLFEGYIET 161
            EE+EQIK+LN++FA+FIDKVRFLEQQNK+L+TK    Q +  +  + NLEPLFE YI  
Sbjct: 161 AEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINN 220

Query: 162 LRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLR 221
           LRR+ + +  + GRL SEL ++Q+++E  K KYE+E++ R  AENEFV LKKDVD AY+ 
Sbjct: 221 LRRQLDNIVGERGRLDSELRNMQDLVEDLKNKYEDEINKRTAAENEFVTLKKDVDAAYMN 280

Query: 222 KSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQ 281
           K +L+A  + L  EI+FLR LY+ E+  +Q+HISDTSVV+ +DN+R+L++D IIAE+KAQ
Sbjct: 281 KVELQAKADTLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQ 340

Query: 282 YDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKC 341
           Y++I  RSRAEAESWY++K EE++ T  RHG+ LR TK+EI E+NRMIQRL +E+++ K 
Sbjct: 341 YEEIAQRSRAEAESWYQTKYEELQITAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKK 400

Query: 342 QNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDI 401
           Q + L+AA+A +EQ+GE AL DA+ KL  LE ALQKAKQD+A L++EYQE+MN KL LD+
Sbjct: 401 QCANLQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDV 460

Query: 402 EIATYRRLLEGEEQRL-CEGVGSVNVCVSSS 431
           EIATYR+LLEGEE RL  EGVG VN+ V  S
Sbjct: 461 EIATYRKLLEGEECRLNGEGVGQVNISVVQS 491


>gi|4504919 keratin 8 [Homo sapiens]
          Length = 483

 Score =  415 bits (1067), Expect = e-116
 Identities = 227/430 (52%), Positives = 299/430 (69%), Gaps = 25/430 (5%)

Query: 5   SYCGGRAFSCISACGPRPGRCCITAAPYRGISCYRG-LTGGFGSHSVCGGFRAGSCGRSF 63
           S  G RAFS  S       R   ++    G S +RG L GG+G  S  GG          
Sbjct: 13  STSGPRAFSSRSYTSGPGSRISSSSFSRVGSSNFRGGLGGGYGGASGMGG---------- 62

Query: 64  GYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDK 123
                         IT V+VN+SLL+PL LE+DPN Q V+ +EKEQIK+LN++FA+FIDK
Sbjct: 63  --------------ITAVTVNQSLLSPLVLEVDPNIQAVRTQEKEQIKTLNNKFASFIDK 108

Query: 124 VRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEADSGRLASELNHV 183
           VRFLEQQNK+LETK    Q ++  +SN++ +FE YI  LRR+ E +  +  +L +EL ++
Sbjct: 109 VRFLEQQNKMLETKWSLLQQQKTARSNMDNMFESYINNLRRQLETLGQEKLKLEAELGNM 168

Query: 184 QEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLY 243
           Q ++E +K KYE+E++ R   ENEFV +KKDVD AY+ K +LE+ +E L  EI+FLR+LY
Sbjct: 169 QGLVEDFKNKYEDEINKRTEMENEFVLIKKDVDEAYMNKVELESRLEGLTDEINFLRQLY 228

Query: 244 EEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCEE 303
           EEEIR LQS ISDTSVV+ +DNSR L+MD IIAE+KAQY+DI  RSRAEAES Y+ K EE
Sbjct: 229 EEEIRELQSQISDTSVVLSMDNSRSLDMDSIIAEVKAQYEDIANRSRAEAESMYQIKYEE 288

Query: 304 MKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSD 363
           +++   +HG+ LRRTK EI+E+NR I RL AE+E  K Q + LEAA+A +EQ+GE A+ D
Sbjct: 289 LQSLAGKHGDDLRRTKTEISEMNRNISRLQAEIEGLKGQRASLEAAIADAEQRGELAIKD 348

Query: 364 ARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEGVGS 423
           A  KL+ELE ALQ+AKQDMA  +REYQE+MN KL LDIEIATYR+LLEGEE RL  G+ +
Sbjct: 349 ANAKLSELEAALQRAKQDMARQLREYQELMNVKLALDIEIATYRKLLEGEESRLESGMQN 408

Query: 424 VNVCVSSSRG 433
           +++   ++ G
Sbjct: 409 MSIHTKTTSG 418


>gi|109148552 keratin 3 [Homo sapiens]
          Length = 628

 Score =  408 bits (1049), Expect = e-114
 Identities = 233/456 (51%), Positives = 306/456 (67%), Gaps = 31/456 (6%)

Query: 4   GSYCGGRAFSCISACGPRPGRCCITAAPYRG-ISCYRGLTGGFGSHSVCGGFRAGSCGRS 62
           G + GGR+ SC  A G   G        + G     RG+ GGFG     GG  AG  G +
Sbjct: 78  GGFGGGRS-SCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGGFGGAGGFGG--AGGFGGA 134

Query: 63  FGY-------RSGGVCGPS-------------PPCITTVSVNESLLTPLNLEIDPNAQCV 102
            G+        SGG  GP              P  I  V++N+SLL PLN+EIDP    V
Sbjct: 135 GGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQEVTINQSLLQPLNVEIDPQIGQV 194

Query: 103 KQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQ----SNLEPLFEGY 158
           K +E+EQIK+LN++FA+FIDKVRFLEQQNK+LETK    Q +        +NLEPLFE +
Sbjct: 195 KAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTSSISGTNNLEPLFENH 254

Query: 159 IETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCA 218
           I  LR   + +  + GRL SEL ++++++E +KKKYE+E++ R  AENEFV LKKDVD A
Sbjct: 255 INYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTAAENEFVTLKKDVDSA 314

Query: 219 YLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEI 278
           Y+ K +L+A V+ALI EIDFLR LY+ E+  +QSHISDTSVV+ +DN+R L++D IIAE+
Sbjct: 315 YMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLSMDNNRSLDLDSIIAEV 374

Query: 279 KAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVEN 338
           +AQY+DI  RS+AEAE+ Y++K  E++ T  RHG+ LR TK EI ELNRMIQRL AE+E 
Sbjct: 375 RAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEIIELNRMIQRLRAEIEG 434

Query: 339 AKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLG 398
            K QN+ L+ A+A++EQ GE AL DA  KL EL+ ALQ+AK D+A L+R+YQE+MN KL 
Sbjct: 435 VKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLARLLRDYQELMNVKLA 494

Query: 399 LDIEIATYRRLLEGEEQRL---CEGVGSVNVCVSSS 431
           LD+EIATYR+LLEGEE R+   C    S++V  SS+
Sbjct: 495 LDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSST 530


>gi|67782365 keratin 7 [Homo sapiens]
          Length = 469

 Score =  407 bits (1046), Expect = e-113
 Identities = 224/420 (53%), Positives = 296/420 (70%), Gaps = 6/420 (1%)

Query: 43  GGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCV 102
           GG GS S+ G    G+       RS    GP    I  V++N+SLL PL L+ DP+ Q V
Sbjct: 32  GGLGSSSLYG---LGASRPRVAVRSA-YGGPVGAGIREVTINQSLLAPLRLDADPSLQRV 87

Query: 103 KQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEP-LFEGYIET 161
           +QEE EQIK+LN++FA+FIDKVRFLEQQNKLLETK    Q ++  +S+  P +FE  I  
Sbjct: 88  RQEESEQIKTLNNKFASFIDKVRFLEQQNKLLETKWTLLQEQKSAKSSRLPDIFEAQIAG 147

Query: 162 LRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLR 221
           LR + E ++ D GRL +EL  +Q+V+E +K KYE+E++ R  AENEFV LKKDVD AY+ 
Sbjct: 148 LRGQLEALQVDGGRLEAELRSMQDVVEDFKNKYEDEINHRTAAENEFVVLKKDVDAAYMS 207

Query: 222 KSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQ 281
           K +LEA V+AL  EI+FLR L E E+  LQS ISDTSVV+ +DNSR L++D IIAE+KAQ
Sbjct: 208 KVELEAKVDALNDEINFLRTLNETELTELQSQISDTSVVLSMDNSRSLDLDGIIAEVKAQ 267

Query: 282 YDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKC 341
           Y+++   SRAEAE+WY++K E ++A   +HG+ LR T+ EI+E+NR IQRL AE++N K 
Sbjct: 268 YEEMAKCSRAEAEAWYQTKFETLQAQAGKHGDDLRNTRNEISEMNRAIQRLQAEIDNIKN 327

Query: 342 QNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDI 401
           Q +KLEAA+A++E++GE AL DAR K  ELE ALQ+ KQDMA  +REYQE+M+ KL LDI
Sbjct: 328 QRAKLEAAIAEAEERGELALKDARAKQEELEAALQRGKQDMARQLREYQELMSVKLALDI 387

Query: 402 EIATYRRLLEGEEQRLC-EGVGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNS 460
           EIATYR+LLEGEE RL  +GVG+VN+ V +S GG   G     T    + +   S  S++
Sbjct: 388 EIATYRKLLEGEESRLAGDGVGAVNISVMNSTGGSSSGGGIGLTLGGTMGSNALSFSSSA 447


>gi|109255249 keratin 4 [Homo sapiens]
          Length = 594

 Score =  404 bits (1039), Expect = e-113
 Identities = 228/467 (48%), Positives = 309/467 (66%), Gaps = 35/467 (7%)

Query: 8   GGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSV----------------- 50
           G R FSC SA      R   ++    G    R  +GGFGS S+                 
Sbjct: 85  GPRGFSCGSAIVGGGKRGAFSSVSMSG-GAGRCSSGGFGSRSLYNLRGNKSISMSVAGSR 143

Query: 51  -------CGGFRAGSCGRSFGYRSGGVCGPS-PPC----ITTVSVNESLLTPLNLEIDPN 98
                   GGF  G  G  FG    G  GP  P C    I  V++N+SLLTPL++EIDP 
Sbjct: 144 QGACFGGAGGFGTGGFGGGFGGSFSGKGGPGFPVCPAGGIQEVTINQSLLTPLHVEIDPE 203

Query: 99  AQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQS--NLEPLFE 156
            Q V+ EE+EQIK LN++FA+FIDKV+FLEQQNK+LETK    Q +    S  NLEPLFE
Sbjct: 204 IQKVRTEEREQIKLLNNKFASFIDKVQFLEQQNKVLETKWNLLQQQTTTTSSKNLEPLFE 263

Query: 157 GYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVD 216
            Y+  LR++ + +  D GRL SEL  +Q+ +E +K KYEEE++ R  AEN+FV LKKDVD
Sbjct: 264 TYLSVLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYEEEINKRTAAENDFVVLKKDVD 323

Query: 217 CAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIA 276
            AYL K +LEA V++L  EI+FL+ LY+ E+  +Q+H+SDTSVV+ +DN+R+L++D IIA
Sbjct: 324 AAYLNKVELEAKVDSLNDEINFLKVLYDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIA 383

Query: 277 EIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEV 336
           E++AQY++I  RS+AEAE+ Y++K ++++ +V +HG+ L+ TK EI ELNRMIQRL AE+
Sbjct: 384 EVRAQYEEIAQRSKAEAEALYQTKVQQLQISVDQHGDNLKNTKSEIAELNRMIQRLRAEI 443

Query: 337 ENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSK 396
           EN K Q   L+ +VA +EQ+GE AL DA  K  ELE ALQ+AK+++A ++REYQE+M+ K
Sbjct: 444 ENIKKQCQTLQVSVADAEQRGENALKDAHSKRVELEAALQQAKEELARMLREYQELMSVK 503

Query: 397 LGLDIEIATYRRLLEGEEQRL---CEGVGSVNVCVSSSRGGVVCGDL 440
           L LDIEIATYR+LLEGEE R+   C+   S++V   S+  G + G L
Sbjct: 504 LALDIEIATYRKLLEGEEYRMSGECQSAVSISVVSGSTSTGGISGGL 550


>gi|15618995 keratin 71 [Homo sapiens]
          Length = 523

 Score =  402 bits (1033), Expect = e-112
 Identities = 228/464 (49%), Positives = 314/464 (67%), Gaps = 35/464 (7%)

Query: 10  RAFSCISACGPRPGRCCITAAPYRGISCY-----RGLTGGFGSHSV--CGGFR----AGS 58
           R F+C S    + G    +A    G S       +GL+GGFGS S+   GG R    A  
Sbjct: 3   RQFTCKSGAAAKGGFSGCSAVLSGGSSSSFRAGSKGLSGGFGSRSLYSLGGVRSLNVASG 62

Query: 59  CGRSFGY-----RSGGVCGP-------SPPCITT--------VSVNESLLTPLNLEIDPN 98
            G+S GY     R+ G  G         P C T         V+VNESLL PLN+E+DP 
Sbjct: 63  SGKSGGYGFGRGRASGFAGSMFGSVALGPVCPTVCPPGGIHQVTVNESLLAPLNVELDPE 122

Query: 99  AQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPLFE 156
            Q V+ +E+EQIK+LN++FA+FIDKVRFLEQQN++LETK +  Q  +   C++NLEP+ E
Sbjct: 123 IQKVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPILE 182

Query: 157 GYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVD 216
           GYI  LR++ E +  D  RL SEL +V++V+E YKK+YEEE++ R  AENEFV LKKDVD
Sbjct: 183 GYISNLRKQLETLSGDRVRLDSELRNVRDVVEDYKKRYEEEINKRTAAENEFVLLKKDVD 242

Query: 217 CAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIA 276
            AY  K +L+A VE++ QEI F R L+E EI  +QSHISD SV++ +DN+R+L++D II 
Sbjct: 243 AAYANKVELQAKVESMDQEIKFFRCLFEAEITQIQSHISDMSVILSMDNNRNLDLDSIID 302

Query: 277 EIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEV 336
           E++ QY++I  +S+AEAE+ Y++K +E++    RHG+ L+ TK EI+EL R+IQR+ +E+
Sbjct: 303 EVRTQYEEIALKSKAEAEALYQTKFQELQLAAGRHGDDLKNTKNEISELTRLIQRIRSEI 362

Query: 337 ENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSK 396
           EN K Q S LE A+A +EQ+G+ AL DAR KL ELEGAL +AK+++A ++REYQE+M+ K
Sbjct: 363 ENVKKQASNLETAIADAEQRGDNALKDARAKLDELEGALHQAKEELARMLREYQELMSLK 422

Query: 397 LGLDIEIATYRRLLEGEEQRLC-EGVGSVNV-CVSSSRGGVVCG 438
           L LD+EIATYR+LLE EE R+  E    V++  +SS+ GG V G
Sbjct: 423 LALDMEIATYRKLLESEECRMSGEFPSPVSISIISSTSGGSVYG 466


>gi|28173564 keratin 73 [Homo sapiens]
          Length = 540

 Score =  396 bits (1018), Expect = e-110
 Identities = 211/398 (53%), Positives = 291/398 (73%), Gaps = 9/398 (2%)

Query: 40  GLTGGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPS---PPCITTVSVNESLLTPLNLEID 96
           G  GG+G      G  +G  G  FG  + G   PS   P  I  V++N+SLL PLN+E+D
Sbjct: 66  GWAGGYGFGR---GRASGFAGSMFGSVALGSVCPSLCPPGGIHQVTINKSLLAPLNVELD 122

Query: 97  PNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPL 154
           P  Q V+ +E+EQIK LN++FA+FIDKVRFLEQQN++LETK +  Q  +   C++NLEP+
Sbjct: 123 PEIQKVRAQEREQIKVLNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPI 182

Query: 155 FEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKD 214
            EGYI  LR++ E +  D  RL SEL  V+EV+E YKK+YEEE++ R TAENEFV LKKD
Sbjct: 183 LEGYISNLRKQLETLSGDRVRLDSELRSVREVVEDYKKRYEEEINKRTTAENEFVVLKKD 242

Query: 215 VDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCI 274
           VD AY  K +L+A V+AL  EI F + LYE E   +QSHISDTS+++ +DN+R+L++D I
Sbjct: 243 VDAAYTSKVELQAKVDALDGEIKFFKCLYEGETAQIQSHISDTSIILSMDNNRNLDLDSI 302

Query: 275 IAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTA 334
           IAE++AQY++I  +S+AEAE+ Y++K +E++    RHG+ L+ TK EI+EL R+IQRL +
Sbjct: 303 IAEVRAQYEEIARKSKAEAEALYQTKFQELQLAAGRHGDDLKHTKNEISELTRLIQRLRS 362

Query: 335 EVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMN 394
           E+E+ K Q + LE A+A +EQ+G+ AL DAR KL ELEGALQ+AK+++A ++REYQE+++
Sbjct: 363 EIESVKKQCANLETAIADAEQRGDCALKDARAKLDELEGALQQAKEELARMLREYQELLS 422

Query: 395 SKLGLDIEIATYRRLLEGEEQRLC-EGVGSVNVCVSSS 431
            KL LDIEIATYR+LLEGEE R+  E   SV++ V +S
Sbjct: 423 VKLSLDIEIATYRKLLEGEECRMSGEYTNSVSISVINS 460


>gi|119395750 keratin 1 [Homo sapiens]
          Length = 644

 Score =  394 bits (1012), Expect = e-109
 Identities = 210/393 (53%), Positives = 291/393 (74%), Gaps = 8/393 (2%)

Query: 43  GGFGSHSVCGGFRAGSCGRS-FGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQC 101
           GGFGS    GGF  G  G   +G   G VC P    I  V++N+SLL PLN+EIDP  Q 
Sbjct: 120 GGFGSGG--GGFGGGGFGGGGYGGGYGPVCPPGG--IQEVTINQSLLQPLNVEIDPEIQK 175

Query: 102 VKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQS--NLEPLFEGYI 159
           VK  E+EQIKSLN++FA+FIDKVRFLEQQN++L+TK +  Q  +      NLEP FE +I
Sbjct: 176 VKSREREQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTHNLEPYFESFI 235

Query: 160 ETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAY 219
             LRR  + +++D  RL SEL ++Q+++E Y+ KYE+E++ R  AENEFV +KKDVD AY
Sbjct: 236 NNLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVDGAY 295

Query: 220 LRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIK 279
           + K DL+A ++ L QEIDFL  LY+ E+  +Q+ IS+T+V++ +DN+R L++D IIAE+K
Sbjct: 296 MTKVDLQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLDLDSIIAEVK 355

Query: 280 AQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENA 339
           AQY+DI  +S+AEAES Y+SK EE++ T  RHG+++R +K EI+ELNR+IQRL +E++N 
Sbjct: 356 AQYEDIAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQRLRSEIDNV 415

Query: 340 KCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGL 399
           K Q S L+ +++ +EQ+GE AL DA+ KL +LE ALQ+AK+D+A L+R+YQE+MN+KL L
Sbjct: 416 KKQISNLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQELMNTKLAL 475

Query: 400 DIEIATYRRLLEGEEQRLC-EGVGSVNVCVSSS 431
           D+EIATYR LLEGEE R+  E   +V+V VS+S
Sbjct: 476 DLEIATYRTLLEGEESRMSGECAPNVSVSVSTS 508


>gi|153791670 keratin 76 [Homo sapiens]
          Length = 638

 Score =  392 bits (1008), Expect = e-109
 Identities = 211/392 (53%), Positives = 280/392 (71%), Gaps = 9/392 (2%)

Query: 40  GLTGGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNA 99
           G  GGFG   V GG   GS G   G+  GG     P  I  V VN+SLL PLN+EIDP  
Sbjct: 123 GGAGGFGGPGVFGG--PGSFGGPGGFGPGGF----PGGIQEVIVNQSLLQPLNVEIDPQI 176

Query: 100 QCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQ--SNLEPLFEG 157
             VK +E+EQIK+LN++FA+FIDKVRFLEQQNK+LETK +  Q +      S+LEP FE 
Sbjct: 177 GQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWELLQQQTTGSGPSSLEPCFES 236

Query: 158 YIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDC 217
           YI  L ++ + +  + G L  EL  +Q+++E +KKKYE+E++ R  AENEFV LKKDVD 
Sbjct: 237 YISFLCKQLDSLLGERGNLEGELKSMQDLVEDFKKKYEDEINKRTAAENEFVGLKKDVDA 296

Query: 218 AYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAE 277
           A++ K +L+A V++L  E+ FLR LYE E+  +QSH SDTSVV+ +DN+R L++  IIAE
Sbjct: 297 AFMNKVELQAKVDSLTDEVSFLRTLYEMELSQMQSHASDTSVVLSMDNNRCLDLGSIIAE 356

Query: 278 IKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVE 337
           ++AQY++I  RS++EAE+ Y++K  E++ T  RHG+ LR TK EI ELNRMIQRL AE+E
Sbjct: 357 VRAQYEEIAQRSKSEAEALYQTKLGELQTTAGRHGDDLRNTKSEIMELNRMIQRLRAEIE 416

Query: 338 NAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKL 397
           N K QN+ L+ A+A++EQ+GE AL DA  KL +L+ ALQKAK D+A L+R+YQE+MN KL
Sbjct: 417 NVKKQNANLQTAIAEAEQRGEMALKDANAKLQDLQTALQKAKDDLARLLRDYQELMNVKL 476

Query: 398 GLDIEIATYRRLLEGEEQRLCEGVGSVNVCVS 429
            LD+EIATYR+LLEGEE R+  G     VC+S
Sbjct: 477 ALDVEIATYRKLLEGEECRM-SGECQSAVCIS 507


>gi|28372503 keratin 72 isoform 1 [Homo sapiens]
          Length = 511

 Score =  391 bits (1005), Expect = e-109
 Identities = 204/386 (52%), Positives = 286/386 (74%), Gaps = 6/386 (1%)

Query: 52  GGFRAGSCGRSFGYRSGGVCGPS---PPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKE 108
           GG   G  G +FG    G   PS   P  I  V+VN+SLL PLN+E+DP  Q V+ +E+E
Sbjct: 68  GGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQRVRAQERE 127

Query: 109 QIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPLFEGYIETLRREA 166
           QIK+LN++FA+FIDKVRFLEQQN++LETK    Q  +   C+ NLEP++EGYI  L+++ 
Sbjct: 128 QIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQL 187

Query: 167 ECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLE 226
           E +  D  RL SEL ++Q+++E YKK+YE E++ R  AENEFV LKKDVD AY+ K +L+
Sbjct: 188 EMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQ 247

Query: 227 ANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIV 286
           A V++L  EI F + LYE EI  +QSHISDTS+V+ +DN+RDL++D IIAE++AQY++I 
Sbjct: 248 AKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIA 307

Query: 287 TRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKL 346
            +S+AEAE+ Y++K +E++ T  +HG+ L+ TK EI+ELNR+IQR+ +E+ N K Q + L
Sbjct: 308 LKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISELNRLIQRIRSEIGNVKKQCADL 367

Query: 347 EAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATY 406
           E A+A +EQ+G+ AL DAR KL ELEGAL +AK+++A ++REYQE+++ KL LD+EIATY
Sbjct: 368 ETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEIATY 427

Query: 407 RRLLEGEEQRLC-EGVGSVNVCVSSS 431
           R+LLE EE R+  E   SV++ V SS
Sbjct: 428 RKLLESEECRMSGEYPNSVSISVISS 453


>gi|226246663 keratin 72 isoform 1 [Homo sapiens]
          Length = 511

 Score =  391 bits (1005), Expect = e-109
 Identities = 204/386 (52%), Positives = 286/386 (74%), Gaps = 6/386 (1%)

Query: 52  GGFRAGSCGRSFGYRSGGVCGPS---PPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKE 108
           GG   G  G +FG    G   PS   P  I  V+VN+SLL PLN+E+DP  Q V+ +E+E
Sbjct: 68  GGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQRVRAQERE 127

Query: 109 QIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPLFEGYIETLRREA 166
           QIK+LN++FA+FIDKVRFLEQQN++LETK    Q  +   C+ NLEP++EGYI  L+++ 
Sbjct: 128 QIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQL 187

Query: 167 ECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLE 226
           E +  D  RL SEL ++Q+++E YKK+YE E++ R  AENEFV LKKDVD AY+ K +L+
Sbjct: 188 EMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQ 247

Query: 227 ANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIV 286
           A V++L  EI F + LYE EI  +QSHISDTS+V+ +DN+RDL++D IIAE++AQY++I 
Sbjct: 248 AKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIA 307

Query: 287 TRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKL 346
            +S+AEAE+ Y++K +E++ T  +HG+ L+ TK EI+ELNR+IQR+ +E+ N K Q + L
Sbjct: 308 LKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISELNRLIQRIRSEIGNVKKQCADL 367

Query: 347 EAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATY 406
           E A+A +EQ+G+ AL DAR KL ELEGAL +AK+++A ++REYQE+++ KL LD+EIATY
Sbjct: 368 ETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEIATY 427

Query: 407 RRLLEGEEQRLC-EGVGSVNVCVSSS 431
           R+LLE EE R+  E   SV++ V SS
Sbjct: 428 RKLLESEECRMSGEYPNSVSISVISS 453


>gi|32567786 keratin 6L [Homo sapiens]
          Length = 535

 Score =  389 bits (999), Expect = e-108
 Identities = 218/441 (49%), Positives = 297/441 (67%), Gaps = 35/441 (7%)

Query: 34  GISCYRGLTGGFGSHS-------------VCGGFRAGSCGRSFGYRSGGVCGPS------ 74
           G  C  G TGGFGS S             V GG   G     FG+ S    G        
Sbjct: 47  GAHCGPG-TGGFGSRSLYNLGGHKSISVSVAGGALLGRALGGFGFGSRAFMGQGAGRQTF 105

Query: 75  -PPC----ITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQ 129
            P C    I  V+VN+SLLTPL++EIDP  Q V+ +E+EQIK+LN++FA+FIDKVRFLEQ
Sbjct: 106 GPACPPGGIQEVTVNQSLLTPLHVEIDPEIQRVRTQEREQIKTLNNKFASFIDKVRFLEQ 165

Query: 130 QNKLLETKLQFYQ----NRECCQSNLEPLFEGYIETLRREAECVEADSGRLASELNHVQE 185
           QNK+LETK    Q    N    ++NLEPLFE Y+ ++R   + ++++ GRL SEL +VQ+
Sbjct: 166 QNKVLETKWALLQEQGQNLGVTRNNLEPLFEAYLGSMRSTLDRLQSERGRLDSELRNVQD 225

Query: 186 VLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEE 245
           ++E +K KYE+E++    AENEFV LKKDVD AY+ + DL   V  L QEIDFL++LYE 
Sbjct: 226 LVEDFKNKYEDEINKHTAAENEFVVLKKDVDAAYMGRMDLHGKVGTLTQEIDFLQQLYEM 285

Query: 246 EIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMK 305
           E+  +Q+H+S+T+VV+ +DN+R+L++D IIAE+KAQY+ I  RSRAEAE+WY++K EE++
Sbjct: 286 ELSQVQTHVSNTNVVLSMDNNRNLDLDSIIAEVKAQYELIAQRSRAEAEAWYQTKYEELQ 345

Query: 306 ATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDAR 365
            T  +HG+ LR TK EI EL R IQRL  E + AK Q  +L+ A+A++EQ+GE AL DA+
Sbjct: 346 VTAGKHGDNLRDTKNEIAELTRTIQRLQGEADAAKKQCQQLQTAIAEAEQRGELALKDAQ 405

Query: 366 CKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRL---CEGVG 422
            KL +L+ AL +AK+D+  L+R+YQE+MN KL LD+EIATYR+LLE EE R+   C    
Sbjct: 406 KKLGDLDVALHQAKEDLTRLLRDYQELMNVKLALDVEIATYRKLLESEESRMSGECPSAV 465

Query: 423 SVNVCVSSSRGGVVCGDLCAS 443
           S++V  +S+    VCG   AS
Sbjct: 466 SISVTGNST---TVCGGGAAS 483


>gi|47132620 keratin 2 [Homo sapiens]
          Length = 639

 Score =  381 bits (979), Expect = e-106
 Identities = 225/484 (46%), Positives = 314/484 (64%), Gaps = 35/484 (7%)

Query: 8   GGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGRSFGYRS 67
           GG  F      G R G      + + G S + G  GGFG     GG R G  G   G   
Sbjct: 79  GGGGFGAAGGFGGRGGGFG-GGSSFGGGSGFSG--GGFGGGGFGGG-RFGGFGGPGGV-- 132

Query: 68  GGVCGPS-------PPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAF 120
           GG+ GP        P  I  VSVN+SLL PLN+++DP  Q VK +E+EQIK+LN++FA+F
Sbjct: 133 GGLGGPGGFGPGGYPGGIHEVSVNQSLLQPLNVKVDPEIQNVKAQEREQIKTLNNKFASF 192

Query: 121 IDKVRFLEQQNKLLETKLQFYQ--NRECCQSNLEPLFEGYIETLRREAECVEADSGRLAS 178
           IDKVRFLEQQN++L+TK +  Q  N      NLEP+F+GYI++L+R  + + A+     S
Sbjct: 193 IDKVRFLEQQNQVLQTKWELLQQMNVGTRPINLEPIFQGYIDSLKRYLDGLTAERTSQNS 252

Query: 179 ELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDF 238
           ELN++Q+++E YKKKYE+E++ R  AEN+FV LKKDVD AY+ K +L++ V+ L QEI+F
Sbjct: 253 ELNNMQDLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYMIKVELQSKVDLLNQEIEF 312

Query: 239 LRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYR 298
           L+ LY+ EI  +   ++DT+V++ +DNSR+L++D IIAE+KAQY++I  RS+ EAE+ Y 
Sbjct: 313 LKVLYDAEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVKAQYEEIAQRSKEEAEALYH 372

Query: 299 SKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGE 358
           SK EE++ TV RHG++L+  K EI+ELNR+IQRL  E+ + K Q   ++ A+A +EQ+GE
Sbjct: 373 SKYEELQVTVGRHGDSLKEIKIEISELNRVIQRLQGEIAHVKKQCKNVQDAIADAEQRGE 432

Query: 359 AALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLC 418
            AL DAR KL +LE ALQ+AK+D+A L+R+YQE+MN KL LD+EIATYR+LLEGEE R+ 
Sbjct: 433 HALKDARNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALDVEIATYRKLLEGEECRM- 491

Query: 419 EGVGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSARVGV 478
                              GDL ++ T  V S+ +SS  + S    G +     S+  G 
Sbjct: 492 ------------------SGDLSSNVTVSVTSSTISSNVA-SKAAFGGSGGRGSSSGGGY 532

Query: 479 CGGS 482
             GS
Sbjct: 533 SSGS 536


>gi|148612803 keratin 6 irs4 [Homo sapiens]
          Length = 529

 Score =  379 bits (973), Expect = e-105
 Identities = 203/397 (51%), Positives = 284/397 (71%), Gaps = 11/397 (2%)

Query: 44  GFGSHSVCGGFRA-GSCGRSFGYRSGG-----VCGPSPPCITTVSVNESLLTPLNLEIDP 97
           GF   S  GG RA G  G  FG  + G     VC P    I  V+VN+SLL PLN+E+DP
Sbjct: 74  GFRPGSGYGGGRASGFAGSMFGSVALGPACLSVCPPGG--IHQVTVNKSLLAPLNVELDP 131

Query: 98  NAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPLF 155
             Q V+ +E+EQIK LN +FA+FIDKVRFLEQQN++LETK +  Q  +   C+ NLEP+ 
Sbjct: 132 EIQKVRAQEREQIKVLNDKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKKNLEPIL 191

Query: 156 EGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDV 215
           EGYI  LR++ E +  D  RL SEL  +++++E YKK+YE E++ R TAENEFV LKKD 
Sbjct: 192 EGYISNLRKQLETLSGDRVRLDSELRSMRDLVEDYKKRYEVEINRRTTAENEFVVLKKDA 251

Query: 216 DCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCII 275
           D AY  K +L+A V++L +EI FL+ LY+ EI  +Q+H S+TSV++ +DN+RDL++D II
Sbjct: 252 DAAYAVKVELQAKVDSLDKEIKFLKCLYDAEIAQIQTHASETSVILSMDNNRDLDLDSII 311

Query: 276 AEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAE 335
           AE++  Y++I  +S+AEAE+ Y++K +E++    RHG+ L+ T+ E+ ELNR+IQR+  E
Sbjct: 312 AEVRMHYEEIALKSKAEAEALYQTKIQELQLAASRHGDDLKHTRSEMVELNRLIQRIRCE 371

Query: 336 VENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNS 395
           + N K Q + LE A+A +EQ+G+ AL DA+ KL ELEGAL +AK+++A ++REYQE+M+ 
Sbjct: 372 IGNVKKQRASLETAIADAEQRGDNALKDAQAKLDELEGALHQAKEELARMLREYQELMSL 431

Query: 396 KLGLDIEIATYRRLLEGEEQRLC-EGVGSVNVCVSSS 431
           KL LD+EIATYR+LLEGEE R+  E   SV++ V SS
Sbjct: 432 KLALDMEIATYRKLLEGEECRMSGENPSSVSISVISS 468


>gi|194018511 keratin 77 [Homo sapiens]
          Length = 578

 Score =  352 bits (904), Expect = 3e-97
 Identities = 190/414 (45%), Positives = 283/414 (68%), Gaps = 15/414 (3%)

Query: 37  CYRGLTGGFGS-------HSVCGGFRAGSCGRS-FGYRSGGVCGPSPPC----ITTVSVN 84
           C  G  GGFG         +  GGF  G  G + FG  + G+ G  P C    I  V++N
Sbjct: 83  CQGGGVGGFGGGRGFGVGSTGAGGFGGGGFGGAGFGTSNFGLGGFGPYCPPGGIQEVTIN 142

Query: 85  ESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQ-- 142
           +SLL PL+LE+DP  Q +K +E+EQI  LN++FA+FIDKVRFLEQQN++L+TK +  Q  
Sbjct: 143 QSLLEPLHLEVDPEIQRIKTQEREQIMVLNNKFASFIDKVRFLEQQNQVLQTKWELLQQV 202

Query: 143 NRECCQSNLEPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRA 202
           N     +NLEPL E YI  LRR+ + + A+  R  +E+  +Q+V+E YK KYE+E++ R 
Sbjct: 203 NTSTGTNNLEPLLENYIGDLRRQVDLLSAEQMRQNAEVRSMQDVVEDYKSKYEDEINKRT 262

Query: 203 TAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVK 262
            +EN+FV LKKDVD AY+ K DLE+ V+ L  E++FL+ L+  E+  +Q+HISDT+V++ 
Sbjct: 263 GSENDFVVLKKDVDAAYVSKVDLESRVDTLTGEVNFLKYLFLTELSQVQTHISDTNVILS 322

Query: 263 LDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEI 322
           +DN+R L++D II  ++ QY+ I  RS+ EAE+ Y++K +E++ T  RHG+ L+ +K EI
Sbjct: 323 MDNNRSLDLDSIIDAVRTQYELIAQRSKDEAEALYQTKYQELQITAGRHGDDLKNSKMEI 382

Query: 323 NELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDM 382
            ELNR +QRL AE+ N K Q  ++++ ++ +E++GE AL DA  KL +LE ALQ++K+++
Sbjct: 383 AELNRTVQRLQAEISNVKKQIEQMQSLISDAEERGEQALQDAWQKLQDLEEALQQSKEEL 442

Query: 383 ACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEGVGS-VNVCVSSSRGGV 435
           A L+R+YQ ++  KL LD+EIATYR+LLEGEE R+   + S V++ V +S+  V
Sbjct: 443 ARLLRDYQAMLGVKLSLDVEIATYRQLLEGEESRMSGELQSHVSISVQNSQVSV 496


>gi|89357932 keratin 5b [Homo sapiens]
          Length = 520

 Score =  346 bits (887), Expect = 3e-95
 Identities = 214/498 (42%), Positives = 303/498 (60%), Gaps = 29/498 (5%)

Query: 10  RAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGR---SFGYR 66
           R FS  SAC  R           RG    R L    G      G   GS GR    FG  
Sbjct: 10  RGFSARSACSARSRGRSRGGFSSRGGFSSRSLNSFGGCLEGSRGSTWGSGGRLGVRFGEW 69

Query: 67  SGG----VCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFID 122
           SGG    +C P    I  V++N++LLTPL +EIDP  Q V+ +E ++I++LN++FA+FID
Sbjct: 70  SGGPGLSLCPPGG--IQEVTINQNLLTPLKIEIDPQFQVVRTQETQEIRTLNNQFASFID 127

Query: 123 KVRFLEQQNKLLETKLQFYQNRECC--QSNLEPLFEGYIETLRREAECVEADSGRLASEL 180
           KVRFLEQQNK+LETK    Q +     Q  LEP+FE  ++ LR++ E ++ + G L +EL
Sbjct: 128 KVRFLEQQNKVLETKWHLLQQQGLSGSQQGLEPVFEACLDQLRKQLEQLQGERGALDAEL 187

Query: 181 NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR 240
              ++  E YK KYEEE   RAT EN+FV LKKDVD  +L K +LE  +EAL + + FL+
Sbjct: 188 KACRDQEEEYKSKYEEEAHRRATLENDFVVLKKDVDGVFLSKMELEGKLEALREYLYFLK 247

Query: 241 RLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK 300
            L EEE+  LQ+  SDTSVV+ +DN+R L+   II E++A+Y++I   S+AEAE+ Y++K
Sbjct: 248 HLNEEELGQLQTQASDTSVVLSMDNNRYLDFSSIITEVRARYEEIARSSKAEAEALYQTK 307

Query: 301 CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA 360
            +E++ +   HG+ ++ TK +I++L++ IQRL ++ EN K QN+ L+AA+  +EQ+GE A
Sbjct: 308 YQELQVSAQLHGDRMQETKVQISQLHQEIQRLQSQTENLKKQNASLQAAITDAEQRGELA 367

Query: 361 LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG 420
           L DA+ K+ ELE AL+ AKQ++A L+ EYQE+ ++KL LD+EIATYRRLLEGEE R+  G
Sbjct: 368 LKDAQAKVDELEAALRMAKQNLARLLCEYQELTSTKLSLDVEIATYRRLLEGEECRM-SG 426

Query: 421 VGSVNVCVSSSRGGVV--------CGDLC--ASTTAPVVSTRVSSVPSNSNVVVGT---- 466
             +  V +SS  G  V         G  C   S      S   S V   SN+++G+    
Sbjct: 427 ECTSQVTISSVGGSAVMSGGVGGGLGSTCGLGSGKGSPGSCCTSIVTGGSNIILGSGKDP 486

Query: 467 -TNACAPSARVGVCGGSC 483
             ++C+ S      G SC
Sbjct: 487 VLDSCSVSG--SSAGSSC 502


>gi|226246665 keratin 72 isoform 2 [Homo sapiens]
          Length = 469

 Score =  335 bits (859), Expect = 5e-92
 Identities = 185/386 (47%), Positives = 256/386 (66%), Gaps = 48/386 (12%)

Query: 52  GGFRAGSCGRSFGYRSGGVCGPS---PPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKE 108
           GG   G  G +FG    G   PS   P  I  V+VN+SLL PLN+E+DP  Q V+ +E+E
Sbjct: 68  GGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQRVRAQERE 127

Query: 109 QIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPLFEGYIETLRREA 166
           QIK+LN++FA+FIDKVRFLEQQN++LETK    Q  +   C+ NLEP++EGYI  L+++ 
Sbjct: 128 QIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQL 187

Query: 167 ECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLE 226
           E +  D  RL SEL ++Q+++E YKK+YE E++ R  AENEFV LKKDVD AY+ K +L+
Sbjct: 188 EMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQ 247

Query: 227 ANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIV 286
           A V++L  EI F + LYE EI  +QSHISDTS+V+ +DN+RDL++D IIAE++AQY++I 
Sbjct: 248 AKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIA 307

Query: 287 TRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKL 346
            +S+AEAE+ Y++KC +                                          L
Sbjct: 308 LKSKAEAETLYQTKCAD------------------------------------------L 325

Query: 347 EAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATY 406
           E A+A +EQ+G+ AL DAR KL ELEGAL +AK+++A ++REYQE+++ KL LD+EIATY
Sbjct: 326 ETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEIATY 385

Query: 407 RRLLEGEEQRLC-EGVGSVNVCVSSS 431
           R+LLE EE R+  E   SV++ V SS
Sbjct: 386 RKLLESEECRMSGEYPNSVSISVISS 411


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.132    0.385 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,851,769
Number of Sequences: 37866
Number of extensions: 797553
Number of successful extensions: 5788
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 160
Number of HSP's successfully gapped in prelim test: 466
Number of HSP's that attempted gapping in prelim test: 4068
Number of HSP's gapped (non-prelim): 1525
length of query: 486
length of database: 18,247,518
effective HSP length: 106
effective length of query: 380
effective length of database: 14,233,722
effective search space: 5408814360
effective search space used: 5408814360
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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