Guide to the Human Genome
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Name: PHEX Sequence: fasta or formatted (749aa) NCBI GI: 90403592
Description:

phosphate-regulating neutral endopeptidase

Referenced in:

Metalloproteases

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.9         52           4
 C cysteine            1.3         10           1
 D aspartate           4.5         34           2
 E glutamate           7.5         56           2
 F phenylalanine       5.3         40           2
 G glycine             5.2         39           2
 H histidine           1.6         12           1
 I isoleucine          5.3         40           1
 K lysine              7.3         55           2
 L leucine             8.8         66           2
 M methionine          2.5         19           2
 N asparagine          5.9         44           2
 P proline             4.4         33           2
 Q glutamine           3.2         24           1
 R arginine            6.3         47           3
 S serine              6.8         51           2
 T threonine           4.4         33           3
 V valine              6.0         45           3
 W tryptophan          2.4         18           2
 Y tyrosine            4.1         31           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   phosphate-regulating neutral endopeptidase 
MMEL1                 0.319   membrane metallo-endopeptidase-like 1 
MME                   0.303   membrane metallo-endopeptidase 
MME                   0.303   membrane metallo-endopeptidase 
MME                   0.303   membrane metallo-endopeptidase 
MME                   0.303   membrane metallo-endopeptidase 
ECE1                  0.297   endothelin converting enzyme 1 isoform 2 
ECE1                  0.297   endothelin converting enzyme 1 isoform 4 
ECE1                  0.297   endothelin converting enzyme 1 isoform 3 
ECE1                  0.297   endothelin converting enzyme 1 isoform 1 
ECE2                  0.290   endothelin converting enzyme 2 isoform B 
ECE2                  0.289   endothelin converting enzyme 2 isoform E 
ECE2                  0.289   endothelin converting enzyme 2 isoform D 
ECE2                  0.289   endothelin converting enzyme 2 isoform A 
ECEL1                 0.232   endothelin converting enzyme-like 1 
KEL                   0.122   Kell blood group, metallo-endopeptidase 
CCDC85C               0.005   coiled-coil domain containing 85C 
CASP8AP2              0.005   caspase 8 associated protein 2 
CASP8AP2              0.005   caspase 8 associated protein 2 
CASP8AP2              0.005   caspase 8 associated protein 2 
ZCCHC18               0.004   zinc finger, CCHC domain containing 18 
ANKRD30A              0.003   ankyrin repeat domain 30A 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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