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Search of human proteins with 7662388
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7662388 intestinal cell kinase [Homo sapiens]
(632 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27477122 intestinal cell kinase [Homo sapiens] 1300 0.0
gi|7662388 intestinal cell kinase [Homo sapiens] 1300 0.0
gi|11496279 male germ cell-associated kinase [Homo sapiens] 666 0.0
gi|7657498 MAPK/MAK/MRK overlapping kinase [Homo sapiens] 239 4e-63
gi|4502709 cell division cycle 2 isoform 1 [Homo sapiens] 221 2e-57
gi|4557439 cyclin-dependent kinase 3 [Homo sapiens] 221 2e-57
gi|195927041 cell division cycle 2 isoform 3 [Homo sapiens] 219 5e-57
gi|16936528 cyclin-dependent kinase 2 isoform 1 [Homo sapiens] 214 2e-55
gi|37595545 PCTAIRE protein kinase 2 [Homo sapiens] 214 2e-55
gi|47078233 PCTAIRE protein kinase 3 isoform a [Homo sapiens] 209 6e-54
gi|47078231 PCTAIRE protein kinase 3 isoform b [Homo sapiens] 209 6e-54
gi|47078229 PCTAIRE protein kinase 3 isoform b [Homo sapiens] 209 6e-54
gi|37596297 cyclin-dependent kinase-like 1 [Homo sapiens] 203 3e-52
gi|197333744 PCTAIRE protein kinase 1 isoform 2 [Homo sapiens] 201 2e-51
gi|5453860 PCTAIRE protein kinase 1 isoform 1 [Homo sapiens] 201 2e-51
gi|148596926 cyclin-dependent kinase 10 isoform a [Homo sapiens] 199 6e-51
gi|89903018 cell cycle related kinase isoform 3 [Homo sapiens] 198 1e-50
gi|83367069 cyclin-dependent kinase-like 5 [Homo sapiens] 196 4e-50
gi|4507281 cyclin-dependent kinase-like 5 [Homo sapiens] 196 4e-50
gi|4502743 cyclin-dependent kinase 7 [Homo sapiens] 188 1e-47
gi|4505569 cyclin-dependent kinase-like 2 [Homo sapiens] 187 3e-47
gi|57222269 cyclin-dependent kinase-like 4 [Homo sapiens] 187 3e-47
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 184 2e-46
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 184 2e-46
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 184 2e-46
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 184 2e-46
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 184 2e-46
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 184 2e-46
gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isof... 184 2e-46
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 184 2e-46
>gi|27477122 intestinal cell kinase [Homo sapiens]
Length = 632
Score = 1300 bits (3364), Expect = 0.0
Identities = 632/632 (100%), Positives = 632/632 (100%)
Query: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHA 60
MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHA
Sbjct: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHA 60
Query: 61 NVVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHG 120
NVVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHG
Sbjct: 61 NVVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHG 120
Query: 121 FFHRDLKPENLLCMGPELVKIADFGLAREIRSKPPYTDYVSTRWYRAPEVLLRSTNYSSP 180
FFHRDLKPENLLCMGPELVKIADFGLAREIRSKPPYTDYVSTRWYRAPEVLLRSTNYSSP
Sbjct: 121 FFHRDLKPENLLCMGPELVKIADFGLAREIRSKPPYTDYVSTRWYRAPEVLLRSTNYSSP 180
Query: 181 IDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFRWPQ 240
IDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFRWPQ
Sbjct: 181 IDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFRWPQ 240
Query: 241 CVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQVGHPLGSTTQNLQDS 300
CVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQVGHPLGSTTQNLQDS
Sbjct: 241 CVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQVGHPLGSTTQNLQDS 300
Query: 301 EKPQKGILEKAGPPPYIKPVPPAQPPAKPHTRISSRQHQASQPPLHLTYPYKAEVSRTDH 360
EKPQKGILEKAGPPPYIKPVPPAQPPAKPHTRISSRQHQASQPPLHLTYPYKAEVSRTDH
Sbjct: 301 EKPQKGILEKAGPPPYIKPVPPAQPPAKPHTRISSRQHQASQPPLHLTYPYKAEVSRTDH 360
Query: 361 PSHLQEDKPSPLLFPSLHNKHPQSKITAGLEHKNGEIKPKSRRRWGLISRSTKDSDDWAD 420
PSHLQEDKPSPLLFPSLHNKHPQSKITAGLEHKNGEIKPKSRRRWGLISRSTKDSDDWAD
Sbjct: 361 PSHLQEDKPSPLLFPSLHNKHPQSKITAGLEHKNGEIKPKSRRRWGLISRSTKDSDDWAD 420
Query: 421 LDDLDFSPSLSRIDLKNKKRQSDDTLCRFESVLDLKPSEPVGTGNSAPTQTSYQRRDTPT 480
LDDLDFSPSLSRIDLKNKKRQSDDTLCRFESVLDLKPSEPVGTGNSAPTQTSYQRRDTPT
Sbjct: 421 LDDLDFSPSLSRIDLKNKKRQSDDTLCRFESVLDLKPSEPVGTGNSAPTQTSYQRRDTPT 480
Query: 481 LRSAAKQHYLKHSRYLPGISIRNGILSNPGKEFIPPNPWSSSGLSGKSSGTMSVISKVNS 540
LRSAAKQHYLKHSRYLPGISIRNGILSNPGKEFIPPNPWSSSGLSGKSSGTMSVISKVNS
Sbjct: 481 LRSAAKQHYLKHSRYLPGISIRNGILSNPGKEFIPPNPWSSSGLSGKSSGTMSVISKVNS 540
Query: 541 VGSSSTSSSGLTGNYVPSFLKKEIGSAMQRVHLAPIPDPSPGYSSLKAMRPHPGRPFFHT 600
VGSSSTSSSGLTGNYVPSFLKKEIGSAMQRVHLAPIPDPSPGYSSLKAMRPHPGRPFFHT
Sbjct: 541 VGSSSTSSSGLTGNYVPSFLKKEIGSAMQRVHLAPIPDPSPGYSSLKAMRPHPGRPFFHT 600
Query: 601 QPRSTPGLIPRPPAAQPVHGRTDWASKYASRR 632
QPRSTPGLIPRPPAAQPVHGRTDWASKYASRR
Sbjct: 601 QPRSTPGLIPRPPAAQPVHGRTDWASKYASRR 632
>gi|7662388 intestinal cell kinase [Homo sapiens]
Length = 632
Score = 1300 bits (3364), Expect = 0.0
Identities = 632/632 (100%), Positives = 632/632 (100%)
Query: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHA 60
MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHA
Sbjct: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHA 60
Query: 61 NVVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHG 120
NVVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHG
Sbjct: 61 NVVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHG 120
Query: 121 FFHRDLKPENLLCMGPELVKIADFGLAREIRSKPPYTDYVSTRWYRAPEVLLRSTNYSSP 180
FFHRDLKPENLLCMGPELVKIADFGLAREIRSKPPYTDYVSTRWYRAPEVLLRSTNYSSP
Sbjct: 121 FFHRDLKPENLLCMGPELVKIADFGLAREIRSKPPYTDYVSTRWYRAPEVLLRSTNYSSP 180
Query: 181 IDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFRWPQ 240
IDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFRWPQ
Sbjct: 181 IDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFRWPQ 240
Query: 241 CVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQVGHPLGSTTQNLQDS 300
CVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQVGHPLGSTTQNLQDS
Sbjct: 241 CVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQVGHPLGSTTQNLQDS 300
Query: 301 EKPQKGILEKAGPPPYIKPVPPAQPPAKPHTRISSRQHQASQPPLHLTYPYKAEVSRTDH 360
EKPQKGILEKAGPPPYIKPVPPAQPPAKPHTRISSRQHQASQPPLHLTYPYKAEVSRTDH
Sbjct: 301 EKPQKGILEKAGPPPYIKPVPPAQPPAKPHTRISSRQHQASQPPLHLTYPYKAEVSRTDH 360
Query: 361 PSHLQEDKPSPLLFPSLHNKHPQSKITAGLEHKNGEIKPKSRRRWGLISRSTKDSDDWAD 420
PSHLQEDKPSPLLFPSLHNKHPQSKITAGLEHKNGEIKPKSRRRWGLISRSTKDSDDWAD
Sbjct: 361 PSHLQEDKPSPLLFPSLHNKHPQSKITAGLEHKNGEIKPKSRRRWGLISRSTKDSDDWAD 420
Query: 421 LDDLDFSPSLSRIDLKNKKRQSDDTLCRFESVLDLKPSEPVGTGNSAPTQTSYQRRDTPT 480
LDDLDFSPSLSRIDLKNKKRQSDDTLCRFESVLDLKPSEPVGTGNSAPTQTSYQRRDTPT
Sbjct: 421 LDDLDFSPSLSRIDLKNKKRQSDDTLCRFESVLDLKPSEPVGTGNSAPTQTSYQRRDTPT 480
Query: 481 LRSAAKQHYLKHSRYLPGISIRNGILSNPGKEFIPPNPWSSSGLSGKSSGTMSVISKVNS 540
LRSAAKQHYLKHSRYLPGISIRNGILSNPGKEFIPPNPWSSSGLSGKSSGTMSVISKVNS
Sbjct: 481 LRSAAKQHYLKHSRYLPGISIRNGILSNPGKEFIPPNPWSSSGLSGKSSGTMSVISKVNS 540
Query: 541 VGSSSTSSSGLTGNYVPSFLKKEIGSAMQRVHLAPIPDPSPGYSSLKAMRPHPGRPFFHT 600
VGSSSTSSSGLTGNYVPSFLKKEIGSAMQRVHLAPIPDPSPGYSSLKAMRPHPGRPFFHT
Sbjct: 541 VGSSSTSSSGLTGNYVPSFLKKEIGSAMQRVHLAPIPDPSPGYSSLKAMRPHPGRPFFHT 600
Query: 601 QPRSTPGLIPRPPAAQPVHGRTDWASKYASRR 632
QPRSTPGLIPRPPAAQPVHGRTDWASKYASRR
Sbjct: 601 QPRSTPGLIPRPPAAQPVHGRTDWASKYASRR 632
>gi|11496279 male germ cell-associated kinase [Homo sapiens]
Length = 623
Score = 666 bits (1719), Expect = 0.0
Identities = 362/644 (56%), Positives = 441/644 (68%), Gaps = 33/644 (5%)
Query: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHA 60
MNRYTT+RQLGDGTYGSVL+G+S ESGEL+AIK+MKRKFYSW+ECMNLREVKSLKKLNHA
Sbjct: 1 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHA 60
Query: 61 NVVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHG 120
NV+KLKEVIRENDHLYFIFEYMKENLYQL+K+RNKLFPES IRNIMYQILQGLAFIHKHG
Sbjct: 61 NVIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHG 120
Query: 121 FFHRDLKPENLLCMGPELVKIADFGLAREIRSKPPYTDYVSTRWYRAPEVLLRSTNYSSP 180
FFHRD+KPENLLCMGPELVKIADFGLARE+RS+PPYTDYVSTRWYRAPEVLLRS+ YSSP
Sbjct: 121 FFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSP 180
Query: 181 IDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFRWPQ 240
IDVWAVG IMAE+Y LRPLFPG SE+D IFKICQVLGTPKK+DWPEGYQL+S+MNFR+PQ
Sbjct: 181 IDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQ 240
Query: 241 CVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQVGHPLGSTTQNLQDS 300
CVP NLKTLIPNAS+EA+QL+ +ML WDPKKRPTASQAL++PYFQVG LG ++ +L+
Sbjct: 241 CVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGPSSNHLESK 300
Query: 301 EKPQKGILEKAGPPPYI----KPVPPA--QPPAKPHTRISSRQHQASQPPLHLTYPYKAE 354
+ K + P + KP+P Q +P + S + Q QPP +L
Sbjct: 301 QSLNKQLQPLESKPSLVEVEPKPLPDIIDQVVGQPQPKTSQQPLQPIQPPQNL------- 353
Query: 355 VSRTDHPSHLQEDKPSPLLFPSLHNKHPQSKITAGLEHKNGEIKPKSRRRWGLISRSTKD 414
S P ++KP LFPS+ P +K L HK+G RRRWG K
Sbjct: 354 -SVQQPPKQQSQEKPPQTLFPSIVKNMP-TKPNGTLSHKSG------RRRWG--QTIFKS 403
Query: 415 SDDWADLDDLDFSPSLSRIDLKN--KKRQSDDTLCRFESVLDLKPSEPVGTGNSAPTQTS 472
D W +L+D DF S S+ K+++ D+ R + + G S P TS
Sbjct: 404 GDSWEELEDYDFGASHSKKPSMGVFKEKRKKDSPFRLPEPVPSGSNHSTGENKSLPAVTS 463
Query: 473 YQRRDTPTLRSAAKQHYLKHSRYLPGISIRNGILSNPGKEFIPPNPWSSSGLSGKSSGTM 532
+ + +KQ+YLK SRYLPG++ + L GKE I P+ WS+ L KS G +
Sbjct: 464 LKSDSELSTAPTSKQYYLKQSRYLPGVNPKKVSLIASGKE-INPHTWSNQ-LFPKSLGPV 521
Query: 533 --SVISKVNSVGSSSTSSSGLTGNYVPSFLKKEIGSAMQRVHLAPIPDPSPGYS-SLKAM 589
+ K ++ G+ + ++ Y+PSFLKKE+ SA QR+HLAP+ + Y+ + K
Sbjct: 522 GAELAFKRSNAGNLGSYATYNQSGYIPSFLKKEVQSAGQRIHLAPLNATASEYTWNTKTG 581
Query: 590 R-PHPGRPFFHTQPRSTPGLIPRPPAAQPVHGRTDWASKYASRR 632
R GR + T ++ R VHGRTDW +KY R
Sbjct: 582 RGQFSGRTYNPT--AKNLNIVNRAQPIPSVHGRTDWVAKYGGHR 623
>gi|7657498 MAPK/MAK/MRK overlapping kinase [Homo sapiens]
Length = 419
Score = 239 bits (611), Expect = 4e-63
Identities = 135/345 (39%), Positives = 204/345 (59%), Gaps = 19/345 (5%)
Query: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLN-H 59
M Y I ++G+GT+ V+ +S+ G A K+MK++F S E+ NLRE+++L++LN H
Sbjct: 1 MKNYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIEQVNNLREIQALRRLNPH 60
Query: 60 ANVVKLKEVI--RENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIH 117
N++ L EV+ R++ L I E M N+Y+LI+ R E I + MYQ+ + L IH
Sbjct: 61 PNILMLHEVVFDRKSGSLALICELMDMNIYELIRGRRYPLSEKKIMHYMYQLCKSLDHIH 120
Query: 118 KHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSKPPYTDYVSTRWYRAPEVLLRSTNY 177
++G FHRD+KPEN+L + +++K+ DFG R + SK PYT+Y+STRWYRAPE LL Y
Sbjct: 121 RNGIFHRDVKPENIL-IKQDVLKLGDFGSCRSVYSKQPYTEYISTRWYRAPECLLTDGFY 179
Query: 178 SSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFR 237
+ +D+W+ GC+ E+ +L+PLFPG +E+D I KI V+GTP + + ++ S AMNF
Sbjct: 180 TYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKILTK-FKQSRAMNFD 238
Query: 238 WPQCVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQVGHPLGSTTQNL 297
+P + + L N S + + LL M+ +DP +R A QAL++PYF Q
Sbjct: 239 FPFKKGSGIPLLTTNLSPQCLSLLHAMVAYDPDERIAAHQALQHPYF----------QEQ 288
Query: 298 QDSEKPQKGILEKAGPPPYIKPVPPAQPPAKPHTRISSRQHQASQ 342
+ +EK G KAG P + P A P +IS + Q
Sbjct: 289 RKTEKRALGSHRKAGFPEH----PVAPEPLSNSCQISKEGRKQKQ 329
>gi|4502709 cell division cycle 2 isoform 1 [Homo sapiens]
Length = 297
Score = 221 bits (563), Expect = 2e-57
Identities = 120/290 (41%), Positives = 175/290 (60%), Gaps = 9/290 (3%)
Query: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMN---LREVKSLKKL 57
M YT I ++G+GTYG V GR +G+++A+KK++ + S EE + +RE+ LK+L
Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLE--SEEEGVPSTAIREISLLKEL 58
Query: 58 NHANVVKLKEVIRENDHLYFIFEYMKENLYQLIKE--RNKLFPESAIRNIMYQILQGLAF 115
H N+V L++V+ ++ LY IFE++ +L + + + S +++ +YQILQG+ F
Sbjct: 59 RHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVF 118
Query: 116 IHKHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSK-PPYTDYVSTRWYRAPEVLLRS 174
H HRDLKP+NLL +K+ADFGLAR YT V T WYR+PEVLL S
Sbjct: 119 CHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGS 178
Query: 175 TNYSSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAM 234
YS+P+D+W++G I AE+ T +PLF G SEID +F+I + LGTP WPE L
Sbjct: 179 ARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYK 238
Query: 235 NFRWPQCVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYF 284
N +P+ P +L + + N + LL ML +DP KR + AL +PYF
Sbjct: 239 N-TFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYF 287
>gi|4557439 cyclin-dependent kinase 3 [Homo sapiens]
Length = 305
Score = 221 bits (563), Expect = 2e-57
Identities = 115/298 (38%), Positives = 177/298 (59%), Gaps = 4/298 (1%)
Query: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKF-YSWEECMNLREVKSLKKLNH 59
M+ + + ++G+GTYG V ++ E+G+L+A+KK++ +RE+ LK+L H
Sbjct: 1 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH 60
Query: 60 ANVVKLKEVIRENDHLYFIFEYMKENLYQLIKER-NKLFPESAIRNIMYQILQGLAFIHK 118
N+V+L +V+ LY +FE++ ++L + + P I++ ++Q+LQG++F H
Sbjct: 61 PNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHS 120
Query: 119 HGFFHRDLKPENLLCMGPELVKIADFGLAREIRSK-PPYTDYVSTRWYRAPEVLLRSTNY 177
H HRDLKP+NLL +K+ADFGLAR YT V T WYRAPE+LL S Y
Sbjct: 121 HRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFY 180
Query: 178 SSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFR 237
++ +D+W++GCI AE+ T + LFPG SEID +F+I ++LGTP + WP QL
Sbjct: 181 TTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKG-S 239
Query: 238 WPQCVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQVGHPLGSTTQ 295
+P+ L+ ++PN E LL +LQ+DP +R TA AL +PYF P + Q
Sbjct: 240 FPKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSSPEPSPAARQ 297
>gi|195927041 cell division cycle 2 isoform 3 [Homo sapiens]
Length = 297
Score = 219 bits (559), Expect = 5e-57
Identities = 119/290 (41%), Positives = 174/290 (60%), Gaps = 9/290 (3%)
Query: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMN---LREVKSLKKL 57
M YT I ++G+GTYG V GR +G+++A+KK++ + S EE + +RE+ LK+L
Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLE--SEEEGVPSTAIREISLLKEL 58
Query: 58 NHANVVKLKEVIRENDHLYFIFEYMKENLYQLIKE--RNKLFPESAIRNIMYQILQGLAF 115
H N+V L++V+ ++ LY IFE++ +L + + + S +++ +YQILQG+ F
Sbjct: 59 RHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVF 118
Query: 116 IHKHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSK-PPYTDYVSTRWYRAPEVLLRS 174
H HRDLKP+NLL +K+ADFGLAR YT T WYR+PEVLL S
Sbjct: 119 CHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLLGS 178
Query: 175 TNYSSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAM 234
YS+P+D+W++G I AE+ T +PLF G SEID +F+I + LGTP WPE L
Sbjct: 179 ARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYK 238
Query: 235 NFRWPQCVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYF 284
N +P+ P +L + + N + LL ML +DP KR + AL +PYF
Sbjct: 239 N-TFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYF 287
>gi|16936528 cyclin-dependent kinase 2 isoform 1 [Homo sapiens]
Length = 298
Score = 214 bits (545), Expect = 2e-55
Identities = 115/288 (39%), Positives = 170/288 (59%), Gaps = 4/288 (1%)
Query: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYS-WEECMNLREVKSLKKLNH 59
M + + ++G+GTYG V R+ +GE++A+KK++ + +RE+ LK+LNH
Sbjct: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
Query: 60 ANVVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKL-FPESAIRNIMYQILQGLAFIHK 118
N+VKL +VI + LY +FE++ ++L + + P I++ ++Q+LQGLAF H
Sbjct: 61 PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS 120
Query: 119 HGFFHRDLKPENLLCMGPELVKIADFGLAREIRSKP-PYTDYVSTRWYRAPEVLLRSTNY 177
H HRDLKP+NLL +K+ADFGLAR YT V T WYRAPE+LL Y
Sbjct: 121 HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY 180
Query: 178 SSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFR 237
S+ +D+W++GCI AE+ T R LFPG SEID +F+I + LGTP + WP G
Sbjct: 181 STAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWP-GVTSMPDYKPS 239
Query: 238 WPQCVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQ 285
+P+ + ++P + LL ML +DP KR +A AL +P+FQ
Sbjct: 240 FPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQ 287
>gi|37595545 PCTAIRE protein kinase 2 [Homo sapiens]
Length = 523
Score = 214 bits (545), Expect = 2e-55
Identities = 111/287 (38%), Positives = 173/287 (60%), Gaps = 3/287 (1%)
Query: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHA 60
M Y + +LG+GTY +V GRS + L+A+K+++ + C +REV LK L HA
Sbjct: 189 METYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHA 248
Query: 61 NVVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHG 120
N+V L +++ + L +FEY+ ++L Q + + + ++ +YQIL+GLA+ H+
Sbjct: 249 NIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRGLAYCHRRK 308
Query: 121 FFHRDLKPENLLCMGPELVKIADFGLAREIRSKP--PYTDYVSTRWYRAPEVLLRSTNYS 178
HRDLKP+NLL +K+ADFGLAR +S P Y++ V T WYR P+VLL S+ YS
Sbjct: 309 VLHRDLKPQNLLINEKGELKLADFGLAR-AKSVPTKTYSNEVVTLWYRPPDVLLGSSEYS 367
Query: 179 SPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFRW 238
+ ID+W VGCI E+ + RPLFPG++ D + I ++LGTP + WP N+ +
Sbjct: 368 TQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGISSNEEFKNYNF 427
Query: 239 PQCVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQ 285
P+ P L P SE ++L+ LQ++ KKR +A +A+++ YF+
Sbjct: 428 PKYKPQPLINHAPRLDSEGIELITKFLQYESKKRVSAEEAMKHVYFR 474
>gi|47078233 PCTAIRE protein kinase 3 isoform a [Homo sapiens]
Length = 504
Score = 209 bits (532), Expect = 6e-54
Identities = 115/302 (38%), Positives = 173/302 (57%), Gaps = 6/302 (1%)
Query: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHA 60
+ Y + +LG+GTY +V GRS + L+A+K+++ + C +REV LK L HA
Sbjct: 171 LETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKNLKHA 230
Query: 61 NVVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHG 120
N+V L ++I + L +FEY+ +L Q + L ++ M+Q+L+GLA+ H
Sbjct: 231 NIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCHHRK 290
Query: 121 FFHRDLKPENLLCMGPELVKIADFGLAREIRSKP--PYTDYVSTRWYRAPEVLLRSTNYS 178
HRDLKP+NLL +K+ADFGLAR +S P Y++ V T WYR P+VLL ST YS
Sbjct: 291 ILHRDLKPQNLLINERGELKLADFGLAR-AKSVPTKTYSNEVVTLWYRPPDVLLGSTEYS 349
Query: 179 SPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFRW 238
+PID+W VGCI E+ T RPLFPG++ + + I ++LGTP + WP S + +
Sbjct: 350 TPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFRTYSF 409
Query: 239 PQCVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQVGHPLGSTTQNLQ 298
P +P L P ++ + LL +L ++ K R +A AL + YF+ LG L+
Sbjct: 410 PCYLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYFR---SLGERVHQLE 466
Query: 299 DS 300
D+
Sbjct: 467 DT 468
>gi|47078231 PCTAIRE protein kinase 3 isoform b [Homo sapiens]
Length = 474
Score = 209 bits (532), Expect = 6e-54
Identities = 115/302 (38%), Positives = 173/302 (57%), Gaps = 6/302 (1%)
Query: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHA 60
+ Y + +LG+GTY +V GRS + L+A+K+++ + C +REV LK L HA
Sbjct: 141 LETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKNLKHA 200
Query: 61 NVVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHG 120
N+V L ++I + L +FEY+ +L Q + L ++ M+Q+L+GLA+ H
Sbjct: 201 NIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCHHRK 260
Query: 121 FFHRDLKPENLLCMGPELVKIADFGLAREIRSKP--PYTDYVSTRWYRAPEVLLRSTNYS 178
HRDLKP+NLL +K+ADFGLAR +S P Y++ V T WYR P+VLL ST YS
Sbjct: 261 ILHRDLKPQNLLINERGELKLADFGLAR-AKSVPTKTYSNEVVTLWYRPPDVLLGSTEYS 319
Query: 179 SPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFRW 238
+PID+W VGCI E+ T RPLFPG++ + + I ++LGTP + WP S + +
Sbjct: 320 TPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFRTYSF 379
Query: 239 PQCVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQVGHPLGSTTQNLQ 298
P +P L P ++ + LL +L ++ K R +A AL + YF+ LG L+
Sbjct: 380 PCYLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYFR---SLGERVHQLE 436
Query: 299 DS 300
D+
Sbjct: 437 DT 438
>gi|47078229 PCTAIRE protein kinase 3 isoform b [Homo sapiens]
Length = 474
Score = 209 bits (532), Expect = 6e-54
Identities = 115/302 (38%), Positives = 173/302 (57%), Gaps = 6/302 (1%)
Query: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHA 60
+ Y + +LG+GTY +V GRS + L+A+K+++ + C +REV LK L HA
Sbjct: 141 LETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKNLKHA 200
Query: 61 NVVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHG 120
N+V L ++I + L +FEY+ +L Q + L ++ M+Q+L+GLA+ H
Sbjct: 201 NIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCHHRK 260
Query: 121 FFHRDLKPENLLCMGPELVKIADFGLAREIRSKP--PYTDYVSTRWYRAPEVLLRSTNYS 178
HRDLKP+NLL +K+ADFGLAR +S P Y++ V T WYR P+VLL ST YS
Sbjct: 261 ILHRDLKPQNLLINERGELKLADFGLAR-AKSVPTKTYSNEVVTLWYRPPDVLLGSTEYS 319
Query: 179 SPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFRW 238
+PID+W VGCI E+ T RPLFPG++ + + I ++LGTP + WP S + +
Sbjct: 320 TPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFRTYSF 379
Query: 239 PQCVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQVGHPLGSTTQNLQ 298
P +P L P ++ + LL +L ++ K R +A AL + YF+ LG L+
Sbjct: 380 PCYLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYFR---SLGERVHQLE 436
Query: 299 DS 300
D+
Sbjct: 437 DT 438
>gi|37596297 cyclin-dependent kinase-like 1 [Homo sapiens]
Length = 358
Score = 203 bits (517), Expect = 3e-52
Identities = 109/289 (37%), Positives = 170/289 (58%), Gaps = 5/289 (1%)
Query: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKK-MKRKFYSWEECMNLREVKSLKKLNH 59
M +Y I ++G+G+YG V R+ ++G+++AIKK ++ + + + LRE++ LK+L H
Sbjct: 2 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKH 61
Query: 60 ANVVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKH 119
N+V L EV R L+ +FEY + + + PE +++I +Q LQ + F HKH
Sbjct: 62 PNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHKH 121
Query: 120 GFFHRDLKPENLLCMGPELVKIADFGLAREIRSKPP-YTDYVSTRWYRAPEVLLRSTNYS 178
HRD+KPEN+L ++K+ DFG AR + YTDYV+TRWYR+PE+L+ T Y
Sbjct: 122 NCIHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDTQYG 181
Query: 179 SPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLG--TPKKTDWPEGYQLSSAMNF 236
P+DVWA+GC+ AE+ + PL+PG S++D ++ I + LG P+ Q S +
Sbjct: 182 PPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSTNQYFSGVKI 241
Query: 237 RWPQCVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQ 285
P+ + L+ PN S A+ LL+ L DP +R T Q L +PYF+
Sbjct: 242 PDPEDM-EPLELKFPNISYPALGLLKGCLHMDPTQRLTCEQLLHHPYFE 289
>gi|197333744 PCTAIRE protein kinase 1 isoform 2 [Homo sapiens]
Length = 502
Score = 201 bits (511), Expect = 2e-51
Identities = 108/302 (35%), Positives = 174/302 (57%), Gaps = 6/302 (1%)
Query: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHA 60
+ Y + +LG+GTY +V G+S + L+A+K+++ + C +REV LK L HA
Sbjct: 168 LETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHA 227
Query: 61 NVVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHG 120
N+V L ++I L +FEY+ ++L Q + + + ++ ++Q+L+GLA+ H+
Sbjct: 228 NIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQK 287
Query: 121 FFHRDLKPENLLCMGPELVKIADFGLAREIRSKP--PYTDYVSTRWYRAPEVLLRSTNYS 178
HRDLKP+NLL +K+ADFGLAR +S P Y++ V T WYR P++LL ST+YS
Sbjct: 288 VLHRDLKPQNLLINERGELKLADFGLAR-AKSIPTKTYSNEVVTLWYRPPDILLGSTDYS 346
Query: 179 SPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFRW 238
+ ID+W VGCI E+ T RPLFPG++ + + I ++LGTP + WP + +
Sbjct: 347 TQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNY 406
Query: 239 PQCVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQVGHPLGSTTQNLQ 298
P+ L + P S+ LL +LQ++ + R +A A+++P+F LG L
Sbjct: 407 PKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFFL---SLGERIHKLP 463
Query: 299 DS 300
D+
Sbjct: 464 DT 465
>gi|5453860 PCTAIRE protein kinase 1 isoform 1 [Homo sapiens]
Length = 496
Score = 201 bits (511), Expect = 2e-51
Identities = 108/302 (35%), Positives = 174/302 (57%), Gaps = 6/302 (1%)
Query: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHA 60
+ Y + +LG+GTY +V G+S + L+A+K+++ + C +REV LK L HA
Sbjct: 162 LETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHA 221
Query: 61 NVVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHG 120
N+V L ++I L +FEY+ ++L Q + + + ++ ++Q+L+GLA+ H+
Sbjct: 222 NIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQK 281
Query: 121 FFHRDLKPENLLCMGPELVKIADFGLAREIRSKP--PYTDYVSTRWYRAPEVLLRSTNYS 178
HRDLKP+NLL +K+ADFGLAR +S P Y++ V T WYR P++LL ST+YS
Sbjct: 282 VLHRDLKPQNLLINERGELKLADFGLAR-AKSIPTKTYSNEVVTLWYRPPDILLGSTDYS 340
Query: 179 SPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFRW 238
+ ID+W VGCI E+ T RPLFPG++ + + I ++LGTP + WP + +
Sbjct: 341 TQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNY 400
Query: 239 PQCVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQVGHPLGSTTQNLQ 298
P+ L + P S+ LL +LQ++ + R +A A+++P+F LG L
Sbjct: 401 PKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFFL---SLGERIHKLP 457
Query: 299 DS 300
D+
Sbjct: 458 DT 459
>gi|148596926 cyclin-dependent kinase 10 isoform a [Homo sapiens]
Length = 360
Score = 199 bits (506), Expect = 6e-51
Identities = 112/289 (38%), Positives = 167/289 (57%), Gaps = 4/289 (1%)
Query: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKR-KFYSWEECMNLREVKSLKKLNH 59
+ + + ++G+GTYG V R ++ E++A+KK++ K +LRE+ L +L H
Sbjct: 36 VKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRH 95
Query: 60 ANVVKLKEVIREN--DHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIH 117
N+V+LKEV+ N + ++ + Y +++L L++ F E+ ++ I+ Q+L+GL ++H
Sbjct: 96 PNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQYLH 155
Query: 118 KHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSK-PPYTDYVSTRWYRAPEVLLRSTN 176
++ HRDLK NLL VK ADFGLAR P T V T WYRAPE+LL +T
Sbjct: 156 RNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTTT 215
Query: 177 YSSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNF 236
++ ID+WAVGCI+AE+ RPL PG SEI I I Q+LGTP + WP +L +
Sbjct: 216 QTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLVGQY 275
Query: 237 RWPQCVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQ 285
+ NNLK P S ++LL + +DPKKR TA L YF+
Sbjct: 276 SLRKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFK 324
>gi|89903018 cell cycle related kinase isoform 3 [Homo sapiens]
Length = 346
Score = 198 bits (503), Expect = 1e-50
Identities = 111/326 (34%), Positives = 182/326 (55%), Gaps = 12/326 (3%)
Query: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMK-RKFYSWEECMNLREVKSLKKL-N 58
M++Y + ++G+G +G V + +E+GE++A+KK+ R+ LRE+K+L+++ +
Sbjct: 1 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED 60
Query: 59 HANVVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHK 118
+ VV+LK V FE+M +L ++++ + ++ +++ + +L+G+AF H
Sbjct: 61 NQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHA 120
Query: 119 HGFFHRDLKPENLLCMGPELVKIADFGLAREIRSKPP--YTDYVSTRWYRAPEVLLRSTN 176
+ HRDLKP NLL +KIADFGLAR YT V+TRWYRAPE+L +
Sbjct: 121 NNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGARQ 180
Query: 177 YSSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNF 236
Y +D+W+VGCIM E+ PLFPG ++I+ + + ++LGTP WPE +L
Sbjct: 181 YDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKI 240
Query: 237 RWPQCVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQVGHPLGSTTQN 296
+ + VP L+ ++P+ S +A+ LL L + P +R AS+AL + YF PL +
Sbjct: 241 SFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTA-PLPAHPSE 299
Query: 297 LQDSEKPQKGILEKAGPPPYIKPVPP 322
L ++ GP P P PP
Sbjct: 300 LPIPQR-------LGGPAPKAHPGPP 318
>gi|83367069 cyclin-dependent kinase-like 5 [Homo sapiens]
Length = 1030
Score = 196 bits (499), Expect = 4e-50
Identities = 160/572 (27%), Positives = 261/572 (45%), Gaps = 76/572 (13%)
Query: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWE-ECMNLREVKSLKKLNH 59
MN++ + +G+G YG VL R E+ E++AIKK K + E + LRE+K L+ L
Sbjct: 10 MNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQ 69
Query: 60 ANVVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKH 119
N+V+LKE R LY +FEY+++N+ +L++E P +++ +YQ+++ + + HK+
Sbjct: 70 ENIVELKEAFRRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWCHKN 129
Query: 120 GFFHRDLKPENLLCMGPELVKIADFGLAREIR--SKPPYTDYVSTRWYRAPEVLLRSTNY 177
HRD+KPENLL +++K+ DFG AR + + YT+YV+TRWYR+PE+LL Y
Sbjct: 130 DIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPELLL-GAPY 188
Query: 178 SSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFR 237
+D+W+VGCI+ E+ +PLFPG SEID +F I +VLG Y R
Sbjct: 189 GKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFYSNPRFHGLR 248
Query: 238 WPQC-VPNNL-KTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQVGHPLGSTTQ 295
+P P +L + + +S + L++++L+ DP R Q L +P FQ TQ
Sbjct: 249 FPAVNHPQSLERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTFQ--------TQ 300
Query: 296 NLQDSEKPQKGILEKAGPPPYIKPVPPAQPPAKPHTRISSRQHQASQPPLHLTYPYKAEV 355
L D P + K P + S ++QA K+
Sbjct: 301 RLLD-RSPSRSAKRK---------------PYHVESSTLSNRNQAG----------KSTA 334
Query: 356 SRTDHPSHLQEDKPSPLLFPSLHNKHPQSKITAGLEHKNGEIKPKSRRRWGLISRSTKDS 415
++ H S+ ++ + + P P ++ + P + + S++
Sbjct: 335 LQSHHRSNSKDIQNLSVGLPRADEGLPANESFLNGNLAGASLSPLHTKTY---QASSQPG 391
Query: 416 DDWADLDDLDFSPSLSRIDLKNKKRQSDDTLCRFESVLDLKPSEPVGT----GNSAPTQT 471
DL + + LS + K+K F+ +D KPSE GT NS Q
Sbjct: 392 STSKDLTNNNIPHLLSPKEAKSK--------TEFDFNIDPKPSEGPGTKYLKSNSRSQQN 443
Query: 472 SYQRRDTPTLRSAAKQHYLKHSRYLPGISIRNGILSNPGKEFIPPNPWSSSGLS----GK 527
+ ++ ++ Q K SR+ +I P SS S K
Sbjct: 444 RHSFMESSQSKAGTLQPNEKQSRH----------------SYIDTIPQSSRSPSYRTKAK 487
Query: 528 SSGTMSVISKVNSVGSSSTS-SSGLTGNYVPS 558
S G +S V+++ + + T Y PS
Sbjct: 488 SHGALSDSKSVSNLSEARAQIAEPSTSRYFPS 519
>gi|4507281 cyclin-dependent kinase-like 5 [Homo sapiens]
Length = 1030
Score = 196 bits (499), Expect = 4e-50
Identities = 160/572 (27%), Positives = 261/572 (45%), Gaps = 76/572 (13%)
Query: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWE-ECMNLREVKSLKKLNH 59
MN++ + +G+G YG VL R E+ E++AIKK K + E + LRE+K L+ L
Sbjct: 10 MNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQ 69
Query: 60 ANVVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKH 119
N+V+LKE R LY +FEY+++N+ +L++E P +++ +YQ+++ + + HK+
Sbjct: 70 ENIVELKEAFRRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWCHKN 129
Query: 120 GFFHRDLKPENLLCMGPELVKIADFGLAREIR--SKPPYTDYVSTRWYRAPEVLLRSTNY 177
HRD+KPENLL +++K+ DFG AR + + YT+YV+TRWYR+PE+LL Y
Sbjct: 130 DIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPELLL-GAPY 188
Query: 178 SSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFR 237
+D+W+VGCI+ E+ +PLFPG SEID +F I +VLG Y R
Sbjct: 189 GKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFYSNPRFHGLR 248
Query: 238 WPQC-VPNNL-KTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQVGHPLGSTTQ 295
+P P +L + + +S + L++++L+ DP R Q L +P FQ TQ
Sbjct: 249 FPAVNHPQSLERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTFQ--------TQ 300
Query: 296 NLQDSEKPQKGILEKAGPPPYIKPVPPAQPPAKPHTRISSRQHQASQPPLHLTYPYKAEV 355
L D P + K P + S ++QA K+
Sbjct: 301 RLLD-RSPSRSAKRK---------------PYHVESSTLSNRNQAG----------KSTA 334
Query: 356 SRTDHPSHLQEDKPSPLLFPSLHNKHPQSKITAGLEHKNGEIKPKSRRRWGLISRSTKDS 415
++ H S+ ++ + + P P ++ + P + + S++
Sbjct: 335 LQSHHRSNSKDIQNLSVGLPRADEGLPANESFLNGNLAGASLSPLHTKTY---QASSQPG 391
Query: 416 DDWADLDDLDFSPSLSRIDLKNKKRQSDDTLCRFESVLDLKPSEPVGT----GNSAPTQT 471
DL + + LS + K+K F+ +D KPSE GT NS Q
Sbjct: 392 STSKDLTNNNIPHLLSPKEAKSK--------TEFDFNIDPKPSEGPGTKYLKSNSRSQQN 443
Query: 472 SYQRRDTPTLRSAAKQHYLKHSRYLPGISIRNGILSNPGKEFIPPNPWSSSGLS----GK 527
+ ++ ++ Q K SR+ +I P SS S K
Sbjct: 444 RHSFMESSQSKAGTLQPNEKQSRH----------------SYIDTIPQSSRSPSYRTKAK 487
Query: 528 SSGTMSVISKVNSVGSSSTS-SSGLTGNYVPS 558
S G +S V+++ + + T Y PS
Sbjct: 488 SHGALSDSKSVSNLSEARAQIAEPSTSRYFPS 519
>gi|4502743 cyclin-dependent kinase 7 [Homo sapiens]
Length = 346
Score = 188 bits (477), Expect = 1e-47
Identities = 110/321 (34%), Positives = 179/321 (55%), Gaps = 8/321 (2%)
Query: 3 RYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSW-EECMN---LREVKSLKKLN 58
RY + LG+G + +V R + +++AIKK+K S ++ +N LRE+K L++L+
Sbjct: 11 RYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELS 70
Query: 59 HANVVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHK 118
H N++ L + ++ +F++M+ +L +IK+ + + S I+ M LQGL ++H+
Sbjct: 71 HPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQ 130
Query: 119 HGFFHRDLKPENLLCMGPELVKIADFGLAREIRS-KPPYTDYVSTRWYRAPEVLLRSTNY 177
H HRDLKP NLL ++K+ADFGLA+ S YT V TRWYRAPE+L + Y
Sbjct: 131 HWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMY 190
Query: 178 SSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFR 237
+D+WAVGCI+AE+ P PG S++D + +I + LGTP + WP+ L + F+
Sbjct: 191 GVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFK 250
Query: 238 WPQCVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQVGHPLGSTTQNL 297
+P L + A + + L++ + ++P R TA+QAL+ YF P + L
Sbjct: 251 SFPGIP--LHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFS-NRPGPTPGCQL 307
Query: 298 QDSEKPQKGILEKAGPPPYIK 318
P + + E++ P IK
Sbjct: 308 PRPNCPVETLKEQSNPALAIK 328
>gi|4505569 cyclin-dependent kinase-like 2 [Homo sapiens]
Length = 493
Score = 187 bits (475), Expect = 3e-47
Identities = 104/307 (33%), Positives = 170/307 (55%), Gaps = 15/307 (4%)
Query: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKK-MKRKFYSWEECMNLREVKSLKKLNH 59
M +Y + +G+G+YG V+ R+ ++G ++AIKK ++ + + +RE+K LK+L H
Sbjct: 1 MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH 60
Query: 60 ANVVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPES----AIRNIMYQILQGLAF 115
N+V L EV ++ Y +FE++ + ++ LFP ++ ++QI+ G+ F
Sbjct: 61 ENLVNLLEVCKKKKRWYLVFEFVDHTILDDLE----LFPNGLDYQVVQKYLFQIINGIGF 116
Query: 116 IHKHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSKPP-YTDYVSTRWYRAPEVLLRS 174
H H HRD+KPEN+L +VK+ DFG AR + + YTDYV+TRWYRAPE+L+
Sbjct: 117 CHSHNIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGD 176
Query: 175 TNYSSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGT--PKKTDWPEGYQLSS 232
Y +DVWA+GC++ E++ PLFPG S+ID ++ I LG P+ + + +
Sbjct: 177 VKYGKAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFNKNPVFA 236
Query: 233 AMNFRWPQCVPNN-LKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQVGHPLG 291
+ R P+ L+ P S + L + L DP KRP ++ L + +FQ+
Sbjct: 237 GV--RLPEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFFQMDGFAE 294
Query: 292 STTQNLQ 298
+Q LQ
Sbjct: 295 RFSQELQ 301
>gi|57222269 cyclin-dependent kinase-like 4 [Homo sapiens]
Length = 315
Score = 187 bits (474), Expect = 3e-47
Identities = 99/287 (34%), Positives = 163/287 (56%), Gaps = 4/287 (1%)
Query: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKK-MKRKFYSWEECMNLREVKSLKKLNH 59
M +Y + + G+G+YG V R+ SG+++A+KK ++ + + + LRE++ LK+L H
Sbjct: 1 MEKYEKLAKTGEGSYGVVFKCRNKTSGQVVAVKKFVESEDDPVVKKIALREIRMLKQLKH 60
Query: 60 ANVVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKH 119
N+V L EV R ++ +FEY L ++ + I+++++Q LQ L F H H
Sbjct: 61 PNLVNLIEVFRRKRKMHLVFEYCDHTLLNELERNPNGVADGVIKSVLWQTLQALNFCHIH 120
Query: 120 GFFHRDLKPENLLCMGPELVKIADFGLAREIRSKPPYTDYVSTRWYRAPEVLLRSTNYSS 179
HRD+KPEN+L ++KI DFG A+ + YTDYV+TRWYRAPE+L+ T Y S
Sbjct: 121 NCIHRDIKPENILITKQGIIKICDFGFAQILIPGDAYTDYVATRWYRAPELLVGDTQYGS 180
Query: 180 PIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLG--TPKKTDWPEGYQLSSAMNFR 237
+D+WA+GC+ AE+ T +PL+PG S++D ++ I + LG P+ + ++
Sbjct: 181 SVDIWAIGCVFAELLTGQPLWPGKSDVDQLYLIIRTLGKLIPRHQSIFKSNGFFHGISIP 240
Query: 238 WPQCVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYF 284
P+ + L+ + A+ ++ L+ +P R T SQ L YF
Sbjct: 241 EPEDM-ETLEEKFSDVHPVALNFMKGCLKMNPDDRLTCSQLLESSYF 286
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 184 bits (468), Expect = 2e-46
Identities = 99/290 (34%), Positives = 164/290 (56%), Gaps = 5/290 (1%)
Query: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMK-RKFYSWEECMNLREVKSLKKLNH 59
+ + + ++ +GTYG V + ++ E++A+K++K K +LRE+ ++ K H
Sbjct: 410 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 469
Query: 60 ANVVKLKEVI--RENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIH 117
N+V ++E++ D +Y + Y++ +L L++ + F ++ +M Q+L+G+ +H
Sbjct: 470 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 529
Query: 118 KHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSK-PPYTDYVSTRWYRAPEVLLRSTN 176
+ HRDLK NLL ++K+ DFGLARE S YT V T+WYRAPE+LL +
Sbjct: 530 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKE 589
Query: 177 YSSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNF 236
YS+ +D+W+VGCI E+ T +PLFPG SEID I K+ + LGTP + WP +L
Sbjct: 590 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKM 649
Query: 237 RWPQCVPNNL-KTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQ 285
+ + NNL K S + L+ L + P +R +A L++ YF+
Sbjct: 650 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFR 699
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 184 bits (468), Expect = 2e-46
Identities = 99/290 (34%), Positives = 164/290 (56%), Gaps = 5/290 (1%)
Query: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMK-RKFYSWEECMNLREVKSLKKLNH 59
+ + + ++ +GTYG V + ++ E++A+K++K K +LRE+ ++ K H
Sbjct: 420 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 479
Query: 60 ANVVKLKEVI--RENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIH 117
N+V ++E++ D +Y + Y++ +L L++ + F ++ +M Q+L+G+ +H
Sbjct: 480 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 539
Query: 118 KHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSK-PPYTDYVSTRWYRAPEVLLRSTN 176
+ HRDLK NLL ++K+ DFGLARE S YT V T+WYRAPE+LL +
Sbjct: 540 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKE 599
Query: 177 YSSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNF 236
YS+ +D+W+VGCI E+ T +PLFPG SEID I K+ + LGTP + WP +L
Sbjct: 600 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKM 659
Query: 237 RWPQCVPNNL-KTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQ 285
+ + NNL K S + L+ L + P +R +A L++ YF+
Sbjct: 660 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFR 709
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 184 bits (468), Expect = 2e-46
Identities = 99/290 (34%), Positives = 164/290 (56%), Gaps = 5/290 (1%)
Query: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMK-RKFYSWEECMNLREVKSLKKLNH 59
+ + + ++ +GTYG V + ++ E++A+K++K K +LRE+ ++ K H
Sbjct: 411 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 470
Query: 60 ANVVKLKEVI--RENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIH 117
N+V ++E++ D +Y + Y++ +L L++ + F ++ +M Q+L+G+ +H
Sbjct: 471 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 530
Query: 118 KHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSK-PPYTDYVSTRWYRAPEVLLRSTN 176
+ HRDLK NLL ++K+ DFGLARE S YT V T WYRAPE+LL +
Sbjct: 531 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE 590
Query: 177 YSSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNF 236
YS+ +D+W+VGCI E+ T +PLFPG SEID I K+ + LGTP + WP +L +
Sbjct: 591 YSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKM 650
Query: 237 RWPQCVPNNL-KTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQ 285
+ + NNL K S + L+ L + P +R +A L++ YF+
Sbjct: 651 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFR 700
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 184 bits (468), Expect = 2e-46
Identities = 99/290 (34%), Positives = 164/290 (56%), Gaps = 5/290 (1%)
Query: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMK-RKFYSWEECMNLREVKSLKKLNH 59
+ + + ++ +GTYG V + ++ E++A+K++K K +LRE+ ++ K H
Sbjct: 420 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 479
Query: 60 ANVVKLKEVI--RENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIH 117
N+V ++E++ D +Y + Y++ +L L++ + F ++ +M Q+L+G+ +H
Sbjct: 480 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 539
Query: 118 KHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSK-PPYTDYVSTRWYRAPEVLLRSTN 176
+ HRDLK NLL ++K+ DFGLARE S YT V T WYRAPE+LL +
Sbjct: 540 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE 599
Query: 177 YSSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNF 236
YS+ +D+W+VGCI E+ T +PLFPG SEID I K+ + LGTP + WP +L +
Sbjct: 600 YSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKM 659
Query: 237 RWPQCVPNNL-KTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQ 285
+ + NNL K S + L+ L + P +R +A L++ YF+
Sbjct: 660 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFR 709
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 184 bits (468), Expect = 2e-46
Identities = 99/290 (34%), Positives = 164/290 (56%), Gaps = 5/290 (1%)
Query: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMK-RKFYSWEECMNLREVKSLKKLNH 59
+ + + ++ +GTYG V + ++ E++A+K++K K +LRE+ ++ K H
Sbjct: 388 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 447
Query: 60 ANVVKLKEVI--RENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIH 117
N+V ++E++ D +Y + Y++ +L L++ + F ++ +M Q+L+G+ +H
Sbjct: 448 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 507
Query: 118 KHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSK-PPYTDYVSTRWYRAPEVLLRSTN 176
+ HRDLK NLL ++K+ DFGLARE S YT V T WYRAPE+LL +
Sbjct: 508 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE 567
Query: 177 YSSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNF 236
YS+ +D+W+VGCI E+ T +PLFPG SEID I K+ + LGTP + WP +L +
Sbjct: 568 YSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKM 627
Query: 237 RWPQCVPNNL-KTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQ 285
+ + NNL K S + L+ L + P +R +A L++ YF+
Sbjct: 628 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFR 677
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 184 bits (468), Expect = 2e-46
Identities = 99/290 (34%), Positives = 164/290 (56%), Gaps = 5/290 (1%)
Query: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMK-RKFYSWEECMNLREVKSLKKLNH 59
+ + + ++ +GTYG V + ++ E++A+K++K K +LRE+ ++ K H
Sbjct: 377 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 436
Query: 60 ANVVKLKEVI--RENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIH 117
N+V ++E++ D +Y + Y++ +L L++ + F ++ +M Q+L+G+ +H
Sbjct: 437 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 496
Query: 118 KHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSK-PPYTDYVSTRWYRAPEVLLRSTN 176
+ HRDLK NLL ++K+ DFGLARE S YT V T WYRAPE+LL +
Sbjct: 497 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE 556
Query: 177 YSSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNF 236
YS+ +D+W+VGCI E+ T +PLFPG SEID I K+ + LGTP + WP +L +
Sbjct: 557 YSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKM 616
Query: 237 RWPQCVPNNL-KTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQ 285
+ + NNL K S + L+ L + P +R +A L++ YF+
Sbjct: 617 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFR 666
>gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isoform
3 [Homo sapiens]
Length = 526
Score = 184 bits (468), Expect = 2e-46
Identities = 99/290 (34%), Positives = 164/290 (56%), Gaps = 5/290 (1%)
Query: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMK-RKFYSWEECMNLREVKSLKKLNH 59
+ + + ++ +GTYG V + ++ E++A+K++K K +LRE+ ++ K H
Sbjct: 166 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 225
Query: 60 ANVVKLKEVI--RENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIH 117
N+V ++E++ D +Y + Y++ +L L++ + F ++ +M Q+L+G+ +H
Sbjct: 226 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 285
Query: 118 KHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSK-PPYTDYVSTRWYRAPEVLLRSTN 176
+ HRDLK NLL ++K+ DFGLARE S YT V T WYRAPE+LL +
Sbjct: 286 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE 345
Query: 177 YSSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNF 236
YS+ +D+W+VGCI E+ T +PLFPG SEID I K+ + LGTP + WP +L +
Sbjct: 346 YSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKM 405
Query: 237 RWPQCVPNNL-KTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQ 285
+ + NNL K S + L+ L + P +R +A L++ YF+
Sbjct: 406 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFR 455
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 184 bits (468), Expect = 2e-46
Identities = 99/290 (34%), Positives = 164/290 (56%), Gaps = 5/290 (1%)
Query: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMK-RKFYSWEECMNLREVKSLKKLNH 59
+ + + ++ +GTYG V + ++ E++A+K++K K +LRE+ ++ K H
Sbjct: 422 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 481
Query: 60 ANVVKLKEVI--RENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIH 117
N+V ++E++ D +Y + Y++ +L L++ + F ++ +M Q+L+G+ +H
Sbjct: 482 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 541
Query: 118 KHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSK-PPYTDYVSTRWYRAPEVLLRSTN 176
+ HRDLK NLL ++K+ DFGLARE S YT V T WYRAPE+LL +
Sbjct: 542 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE 601
Query: 177 YSSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNF 236
YS+ +D+W+VGCI E+ T +PLFPG SEID I K+ + LGTP + WP +L +
Sbjct: 602 YSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKM 661
Query: 237 RWPQCVPNNL-KTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQ 285
+ + NNL K S + L+ L + P +R +A L++ YF+
Sbjct: 662 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFR 711
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.133 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,688,647
Number of Sequences: 37866
Number of extensions: 1554318
Number of successful extensions: 11511
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 725
Number of HSP's successfully gapped in prelim test: 270
Number of HSP's that attempted gapping in prelim test: 8103
Number of HSP's gapped (non-prelim): 2098
length of query: 632
length of database: 18,247,518
effective HSP length: 108
effective length of query: 524
effective length of database: 14,157,990
effective search space: 7418786760
effective search space used: 7418786760
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.