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Search of human proteins with 61743978
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|61743978 stabilin 1 precursor [Homo sapiens]
(2570 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|61743978 stabilin 1 precursor [Homo sapiens] 5524 0.0
gi|61743980 stabilin 2 precursor [Homo sapiens] 2067 0.0
gi|26051243 tumor necrosis factor, alpha-induced protein 6 precu... 117 2e-25
gi|126091152 cubilin [Homo sapiens] 114 1e-24
gi|24430141 fibrillin 1 precursor [Homo sapiens] 113 2e-24
gi|122937343 platelet endothelial aggregation receptor 1 [Homo s... 112 5e-24
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] 112 5e-24
gi|134244285 Notch homolog 3 [Homo sapiens] 108 9e-23
gi|66346695 fibrillin 2 precursor [Homo sapiens] 108 9e-23
gi|110735443 delta-like 1 [Homo sapiens] 105 4e-22
gi|24041035 notch 2 preproprotein [Homo sapiens] 105 4e-22
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 105 6e-22
gi|56237021 fibrillin 3 precursor [Homo sapiens] 105 8e-22
gi|14192943 multiple EGF-like-domains 10 [Homo sapiens] 103 3e-21
gi|110347437 latent transforming growth factor beta binding prot... 100 2e-20
gi|110347412 latent transforming growth factor beta binding prot... 100 2e-20
gi|110347431 latent transforming growth factor beta binding prot... 100 2e-20
gi|144953895 nidogen 2 precursor [Homo sapiens] 99 4e-20
gi|55770876 notch4 preproprotein [Homo sapiens] 99 5e-20
gi|148833508 notch1 preproprotein [Homo sapiens] 98 1e-19
gi|188528675 slit homolog 1 [Homo sapiens] 97 2e-19
gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens] 96 5e-19
gi|222352164 nel-like 1 isoform 1 precursor [Homo sapiens] 96 6e-19
gi|115298674 nidogen 1 precursor [Homo sapiens] 95 8e-19
gi|46249414 latent transforming growth factor beta binding prote... 95 1e-18
gi|46249412 latent transforming growth factor beta binding prote... 95 1e-18
gi|9506545 delta-like 4 protein precursor [Homo sapiens] 95 1e-18
gi|75709198 nephronectin [Homo sapiens] 95 1e-18
gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s... 94 2e-18
gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa... 94 2e-18
>gi|61743978 stabilin 1 precursor [Homo sapiens]
Length = 2570
Score = 5524 bits (14331), Expect = 0.0
Identities = 2570/2570 (100%), Positives = 2570/2570 (100%)
Query: 1 MAGPRGLLPLCLLAFCLAGFSFVRGQVLFKGCDVKTTFVTHVPCTSCAAIKKQTCPSGWL 60
MAGPRGLLPLCLLAFCLAGFSFVRGQVLFKGCDVKTTFVTHVPCTSCAAIKKQTCPSGWL
Sbjct: 1 MAGPRGLLPLCLLAFCLAGFSFVRGQVLFKGCDVKTTFVTHVPCTSCAAIKKQTCPSGWL 60
Query: 61 RELPDQITQDCRYEVQLGGSMVSMSGCRRKCRKQVVQKACCPGYWGSRCHECPGGAETPC 120
RELPDQITQDCRYEVQLGGSMVSMSGCRRKCRKQVVQKACCPGYWGSRCHECPGGAETPC
Sbjct: 61 RELPDQITQDCRYEVQLGGSMVSMSGCRRKCRKQVVQKACCPGYWGSRCHECPGGAETPC 120
Query: 121 NGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHGVCNHGPRGDGS 180
NGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHGVCNHGPRGDGS
Sbjct: 121 NGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHGVCNHGPRGDGS 180
Query: 181 CLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQGSECRAPNPCWPSP 240
CLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQGSECRAPNPCWPSP
Sbjct: 181 CLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQGSECRAPNPCWPSP 240
Query: 241 CSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFC 300
CSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFC
Sbjct: 241 CSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFC 300
Query: 301 TCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVTADGKTSCVCRESEVGDGRACYGHLL 360
TCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVTADGKTSCVCRESEVGDGRACYGHLL
Sbjct: 301 TCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVTADGKTSCVCRESEVGDGRACYGHLL 360
Query: 361 HEVQKATQTGRVFLQLRVAVAMMDQGCREILTTAGPFTVLVPSVSSFSSRTMNASLAQQL 420
HEVQKATQTGRVFLQLRVAVAMMDQGCREILTTAGPFTVLVPSVSSFSSRTMNASLAQQL
Sbjct: 361 HEVQKATQTGRVFLQLRVAVAMMDQGCREILTTAGPFTVLVPSVSSFSSRTMNASLAQQL 420
Query: 421 CRQHIIAGQHILEDTRTQQTRRWWTLAGQEITVTFNQFTKYSYKYKDQPQQTFNIYKANN 480
CRQHIIAGQHILEDTRTQQTRRWWTLAGQEITVTFNQFTKYSYKYKDQPQQTFNIYKANN
Sbjct: 421 CRQHIIAGQHILEDTRTQQTRRWWTLAGQEITVTFNQFTKYSYKYKDQPQQTFNIYKANN 480
Query: 481 IAANGVFHVVTGLRWQAPSGTPGDPKRTIGQILASTEAFSRFETILENCGLPSILDGPGP 540
IAANGVFHVVTGLRWQAPSGTPGDPKRTIGQILASTEAFSRFETILENCGLPSILDGPGP
Sbjct: 481 IAANGVFHVVTGLRWQAPSGTPGDPKRTIGQILASTEAFSRFETILENCGLPSILDGPGP 540
Query: 541 FTVFAPSNEAVDSLRDGRLIYLFTAGLSKLQELVRYHIYNHGQLTVEKLISKGRILTMAN 600
FTVFAPSNEAVDSLRDGRLIYLFTAGLSKLQELVRYHIYNHGQLTVEKLISKGRILTMAN
Sbjct: 541 FTVFAPSNEAVDSLRDGRLIYLFTAGLSKLQELVRYHIYNHGQLTVEKLISKGRILTMAN 600
Query: 601 QVLAVNISEEGRILLGPEGVPLQRVDVMAANGVIHMLDGILLPPTILPILPKHCSEEQHK 660
QVLAVNISEEGRILLGPEGVPLQRVDVMAANGVIHMLDGILLPPTILPILPKHCSEEQHK
Sbjct: 601 QVLAVNISEEGRILLGPEGVPLQRVDVMAANGVIHMLDGILLPPTILPILPKHCSEEQHK 660
Query: 661 IVAGSCVDCQALNTSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKGCASYCNQTIMEQGC 720
IVAGSCVDCQALNTSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKGCASYCNQTIMEQGC
Sbjct: 661 IVAGSCVDCQALNTSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKGCASYCNQTIMEQGC 720
Query: 721 CKGFFGPDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQC 780
CKGFFGPDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQC
Sbjct: 721 CKGFFGPDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQC 780
Query: 781 QEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQ 840
QEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQ
Sbjct: 781 QEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQ 840
Query: 841 EGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGR 900
EGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGR
Sbjct: 841 EGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGR 900
Query: 901 VCVAIDECELDMRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHG 960
VCVAIDECELDMRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHG
Sbjct: 901 VCVAIDECELDMRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHG 960
Query: 961 LATCRAVGGGQRVCTCPPGFGGDGFSCYGDIFRELEANAHFSIFYQWLKSAGITLPADRR 1020
LATCRAVGGGQRVCTCPPGFGGDGFSCYGDIFRELEANAHFSIFYQWLKSAGITLPADRR
Sbjct: 961 LATCRAVGGGQRVCTCPPGFGGDGFSCYGDIFRELEANAHFSIFYQWLKSAGITLPADRR 1020
Query: 1021 VTALVPSEAAVRQLSPEDRAFWLQPRTLPNLVRAHFLQGALFEEELARLGGQEVATLNPT 1080
VTALVPSEAAVRQLSPEDRAFWLQPRTLPNLVRAHFLQGALFEEELARLGGQEVATLNPT
Sbjct: 1021 VTALVPSEAAVRQLSPEDRAFWLQPRTLPNLVRAHFLQGALFEEELARLGGQEVATLNPT 1080
Query: 1081 TRWEIRNISGRVWVQNASVDVADLLATNGVLHILSQVLLPPRGDVPGGQGLLQQLDLVPA 1140
TRWEIRNISGRVWVQNASVDVADLLATNGVLHILSQVLLPPRGDVPGGQGLLQQLDLVPA
Sbjct: 1081 TRWEIRNISGRVWVQNASVDVADLLATNGVLHILSQVLLPPRGDVPGGQGLLQQLDLVPA 1140
Query: 1141 FSLFRELLQHHGLVPQIEAATAYTIFVPTNRSLEAQGNSSHLDADTVRHHVVLGEALSME 1200
FSLFRELLQHHGLVPQIEAATAYTIFVPTNRSLEAQGNSSHLDADTVRHHVVLGEALSME
Sbjct: 1141 FSLFRELLQHHGLVPQIEAATAYTIFVPTNRSLEAQGNSSHLDADTVRHHVVLGEALSME 1200
Query: 1201 TLRKGGHRNSLLGPAHWIVFYNHSGQPEVNHVPLEGPMLEAPGRSLIGLSGVLTVGSSRC 1260
TLRKGGHRNSLLGPAHWIVFYNHSGQPEVNHVPLEGPMLEAPGRSLIGLSGVLTVGSSRC
Sbjct: 1201 TLRKGGHRNSLLGPAHWIVFYNHSGQPEVNHVPLEGPMLEAPGRSLIGLSGVLTVGSSRC 1260
Query: 1261 LHSHAEALREKCVNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKKIQVPDC 1320
LHSHAEALREKCVNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKKIQVPDC
Sbjct: 1261 LHSHAEALREKCVNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKKIQVPDC 1320
Query: 1321 CPGFFGTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCT 1380
CPGFFGTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCT
Sbjct: 1321 CPGFFGTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCT 1380
Query: 1381 GVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTC 1440
GVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTC
Sbjct: 1381 GVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTC 1440
Query: 1441 ACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINS 1500
ACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINS
Sbjct: 1441 ACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINS 1500
Query: 1501 CLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKST 1560
CLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKST
Sbjct: 1501 CLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKST 1560
Query: 1561 GDGQRTCTCDTAHTVGDGLTCRARVGLELLRDKHASFFSLRLLEYKELKGDGPFTIFVPH 1620
GDGQRTCTCDTAHTVGDGLTCRARVGLELLRDKHASFFSLRLLEYKELKGDGPFTIFVPH
Sbjct: 1561 GDGQRTCTCDTAHTVGDGLTCRARVGLELLRDKHASFFSLRLLEYKELKGDGPFTIFVPH 1620
Query: 1621 ADLMSNLSQDELARIRAHRQLVFRYHVVGCRRLRSEDLLEQGYATALSGHPLRFSEREGS 1680
ADLMSNLSQDELARIRAHRQLVFRYHVVGCRRLRSEDLLEQGYATALSGHPLRFSEREGS
Sbjct: 1621 ADLMSNLSQDELARIRAHRQLVFRYHVVGCRRLRSEDLLEQGYATALSGHPLRFSEREGS 1680
Query: 1681 IYLNDFARVVSSDHEAVNGILHFIDRVLLPPEALHWEPDDAPIPRRNVTAAAQGFGYKIF 1740
IYLNDFARVVSSDHEAVNGILHFIDRVLLPPEALHWEPDDAPIPRRNVTAAAQGFGYKIF
Sbjct: 1681 IYLNDFARVVSSDHEAVNGILHFIDRVLLPPEALHWEPDDAPIPRRNVTAAAQGFGYKIF 1740
Query: 1741 SGLLKVAGLLPLLREASHRPFTMLWPTDAAFRALPPDRQAWLYHEDHRDKLAAILRGHMI 1800
SGLLKVAGLLPLLREASHRPFTMLWPTDAAFRALPPDRQAWLYHEDHRDKLAAILRGHMI
Sbjct: 1741 SGLLKVAGLLPLLREASHRPFTMLWPTDAAFRALPPDRQAWLYHEDHRDKLAAILRGHMI 1800
Query: 1801 RNVEALASDLPNLGPLRTMHGTPISFSCSRTRAGELMVGEDDARIVQRHLPFEGGLAYGI 1860
RNVEALASDLPNLGPLRTMHGTPISFSCSRTRAGELMVGEDDARIVQRHLPFEGGLAYGI
Sbjct: 1801 RNVEALASDLPNLGPLRTMHGTPISFSCSRTRAGELMVGEDDARIVQRHLPFEGGLAYGI 1860
Query: 1861 DQLLEPPGLGARCDHFETRPLRLNTCSICGLEPPCPEGSQEQGSPEACWRFYPKFWTSPP 1920
DQLLEPPGLGARCDHFETRPLRLNTCSICGLEPPCPEGSQEQGSPEACWRFYPKFWTSPP
Sbjct: 1861 DQLLEPPGLGARCDHFETRPLRLNTCSICGLEPPCPEGSQEQGSPEACWRFYPKFWTSPP 1920
Query: 1921 LHSLGLRSVWVHPSLWGRPQGLGRGCHRNCVTTTWKPSCCPGHYGSECQACPGGPSSPCS 1980
LHSLGLRSVWVHPSLWGRPQGLGRGCHRNCVTTTWKPSCCPGHYGSECQACPGGPSSPCS
Sbjct: 1921 LHSLGLRSVWVHPSLWGRPQGLGRGCHRNCVTTTWKPSCCPGHYGSECQACPGGPSSPCS 1980
Query: 1981 DRGVCMDGMSGSGQCLCRSGFAGTACELCAPGAFGPHCQACRCTVHGRCDEGLGGSGSCF 2040
DRGVCMDGMSGSGQCLCRSGFAGTACELCAPGAFGPHCQACRCTVHGRCDEGLGGSGSCF
Sbjct: 1981 DRGVCMDGMSGSGQCLCRSGFAGTACELCAPGAFGPHCQACRCTVHGRCDEGLGGSGSCF 2040
Query: 2041 CDEGWTGPRCEVQLELQPVCTPPCAPEAVCRAGNSCECSLGYEGDGRVCTVADLCQDGHG 2100
CDEGWTGPRCEVQLELQPVCTPPCAPEAVCRAGNSCECSLGYEGDGRVCTVADLCQDGHG
Sbjct: 2041 CDEGWTGPRCEVQLELQPVCTPPCAPEAVCRAGNSCECSLGYEGDGRVCTVADLCQDGHG 2100
Query: 2101 GCSEHANCSQVGTMVTCTCLPDYEGDGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRC 2160
GCSEHANCSQVGTMVTCTCLPDYEGDGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRC
Sbjct: 2101 GCSEHANCSQVGTMVTCTCLPDYEGDGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRC 2160
Query: 2161 ECHAGYVGDGLQCLEESEPPVDRCLGQPPPCHSDAMCTDLHFQEKRAGVFHLQATSGPYG 2220
ECHAGYVGDGLQCLEESEPPVDRCLGQPPPCHSDAMCTDLHFQEKRAGVFHLQATSGPYG
Sbjct: 2161 ECHAGYVGDGLQCLEESEPPVDRCLGQPPPCHSDAMCTDLHFQEKRAGVFHLQATSGPYG 2220
Query: 2221 LNFSEAEAACEAQGAVLASFPQLSAAQQLGFHLCLMGWLANGSTAHPVVFPVADCGNGRV 2280
LNFSEAEAACEAQGAVLASFPQLSAAQQLGFHLCLMGWLANGSTAHPVVFPVADCGNGRV
Sbjct: 2221 LNFSEAEAACEAQGAVLASFPQLSAAQQLGFHLCLMGWLANGSTAHPVVFPVADCGNGRV 2280
Query: 2281 GIVSLGARKNLSERWDAYCFRVQDVACRCRNGFVGDGISTCNGKLLDVLAATANFSTFYG 2340
GIVSLGARKNLSERWDAYCFRVQDVACRCRNGFVGDGISTCNGKLLDVLAATANFSTFYG
Sbjct: 2281 GIVSLGARKNLSERWDAYCFRVQDVACRCRNGFVGDGISTCNGKLLDVLAATANFSTFYG 2340
Query: 2341 MLLGYANATQRGLDFLDFLDDELTYKTLFVPVNEGFVDNMTLSGPDLELHASNATLLSAN 2400
MLLGYANATQRGLDFLDFLDDELTYKTLFVPVNEGFVDNMTLSGPDLELHASNATLLSAN
Sbjct: 2341 MLLGYANATQRGLDFLDFLDDELTYKTLFVPVNEGFVDNMTLSGPDLELHASNATLLSAN 2400
Query: 2401 ASQGKLLPAHSGLSLIISDAGPDNSSWAPVAPGTVVVSRIIVWDIMAFNGIIHALASPLL 2460
ASQGKLLPAHSGLSLIISDAGPDNSSWAPVAPGTVVVSRIIVWDIMAFNGIIHALASPLL
Sbjct: 2401 ASQGKLLPAHSGLSLIISDAGPDNSSWAPVAPGTVVVSRIIVWDIMAFNGIIHALASPLL 2460
Query: 2461 APPQPQAVLAPEAPPVAAGVGAVLAAGALLGLVAGALYLRARGKPMGFGFSAFQAEDDAD 2520
APPQPQAVLAPEAPPVAAGVGAVLAAGALLGLVAGALYLRARGKPMGFGFSAFQAEDDAD
Sbjct: 2461 APPQPQAVLAPEAPPVAAGVGAVLAAGALLGLVAGALYLRARGKPMGFGFSAFQAEDDAD 2520
Query: 2521 DDFSPWQEGTNPTLVSVPNPVFGSDTFCEPFDDSLLEEDFPDTQRILTVK 2570
DDFSPWQEGTNPTLVSVPNPVFGSDTFCEPFDDSLLEEDFPDTQRILTVK
Sbjct: 2521 DDFSPWQEGTNPTLVSVPNPVFGSDTFCEPFDDSLLEEDFPDTQRILTVK 2570
>gi|61743980 stabilin 2 precursor [Homo sapiens]
Length = 2551
Score = 2067 bits (5356), Expect = 0.0
Identities = 1048/2567 (40%), Positives = 1441/2567 (56%), Gaps = 104/2567 (4%)
Query: 32 CDVKTTFVTHVPCTSCAAIKKQTCPSGWLRELPDQI-TQDCRYEVQLGGSMVSMSGCRRK 90
CD K+ C SCA CP G+ + +DCRY ++ +S+ GCR
Sbjct: 31 CDRKSLLTIRTECRSCALNLGVKCPDGYTMITSGSVGVRDCRYTFEVRTYSLSLPGCRHI 90
Query: 91 CRKQVVQKACCPGYWGSRCHECPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQEC 150
CRK +Q CCPG WG C ECPGGA +PCNG G+C +GM+ NGTC CQE F G+AC+ C
Sbjct: 91 CRKDYLQPRCCPGRWGPDCIECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETC 150
Query: 151 QDPNRFGPDCQSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQELPVCQELRCPQNTQC 210
D N FGP C SVC+CVHGVCN G GDG+C C++ YTGP CD+ +P C L CP+N++C
Sbjct: 151 ADDNLFGPSCSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRC 210
Query: 211 SAEAPS-----CRCLPGYTQQGSECRAPNPCWPSPCSLLAQCSVSPKGQAQCHCPENYHG 265
S C+CLP Y G C NPC C A C+ + C C E Y G
Sbjct: 211 SPSTEDENKLECKCLPNYRGDGKYCDPINPCLRKICHPHAHCTYLGPNRHSCTCQEGYRG 270
Query: 266 DGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPGLVSINSNASAGCFAFC-SPF 324
DG VCLP DPC N G CP+ ST+C Y PGQ+ C C+ + C S
Sbjct: 271 DGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKEHYQNFVPGVGCSMTDICKSDN 330
Query: 325 SCDRSATCQVTADGKTSCVCRESEVGDGRACYGHLLHEVQKATQTGRVFLQLRVA--VAM 382
C R+A C A G+T C+C++ VGDG CYG+++ +++ R Q R+ +++
Sbjct: 331 PCHRNANCTTVAPGRTECICQKGYVGDGLTCYGNIMERLRELNTEPRGKWQGRLTSFISL 390
Query: 383 MDQGCREILTTAGPFTVLVPSVSSFSSRTMNASL-----AQQLCRQHIIAGQHILEDTRT 437
+D+ L+ GPFTVL+P+ +N L AQ + HIIAGQ +E
Sbjct: 391 LDKAYAWPLSKLGPFTVLLPTDKGLKGFNVNELLVDNKAAQYFVKLHIIAGQMNIE--YM 448
Query: 438 QQTRRWWTLAGQEITVTFNQFTKYSYKYK-DQPQQTFNIYKANNIAANGVFHVVTGLRWQ 496
T ++TL G+ + FN K K ++ I + + IA+NG+ H++ +
Sbjct: 449 NNTDMFYTLTGKSGEI-FNSDKDNQIKLKLHGGKKKVKIIQGDIIASNGLLHILDRAMDK 507
Query: 497 APSGTPGDPKRTIGQILASTEAFSRFETILENCGLPSILDGPG---PFTVFAPSNEAVDS 553
+ ++TI +L +S+F ++LE L LD G P+T+F P+NEA+++
Sbjct: 508 LEPTFESNNEQTIMTMLQPR--YSKFRSLLEETNLGHALDEDGVGGPYTIFVPNNEALNN 565
Query: 554 LRDGRLIYLFTA-GLSKLQELVRYHIYNHGQLTVEKLISKGRILTMANQVLAVNISEEGR 612
++DG L YL + G KL ELVRYHI QL V LIS I +MANQ++ N ++ G+
Sbjct: 566 MKDGTLDYLLSPEGSRKLLELVRYHIVPFTQLEVATLISTPHIRSMANQLIQFNTTDNGQ 625
Query: 613 ILLGPEGVPLQRVDVMAANGVIHMLDGILLPPTILPILPKHCSEEQHKIVAGSCVDCQAL 672
IL V ++ +++ A NG I+ L G+L+PP+I+PILP C E + ++ G+CV C +
Sbjct: 626 ILAND--VAMEEIEITAKNGRIYTLTGVLIPPSIVPILPHRCDETKREMKLGTCVSCSLV 683
Query: 673 NTSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKGCASYCNQTIMEQGCCKGFFGPDCTQC 732
S CP NS +F CVY LK GCA YCN T+ CCKGF+GPDC QC
Sbjct: 684 YWSRCPANSEPTALFTHRCVY---SGRFGSLKSGCARYCNATVKIPKCCKGFYGPDCNQC 740
Query: 733 PGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQCQEDCGCVHGLCD 792
PGGFSNPC G G C+D + GNG C+C ++G C CS+PNK+G +C + C CVHG C+
Sbjct: 741 PGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYGPRCNKKCLCVHGTCN 800
Query: 793 NRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGF 852
NR S G C GTC G +GR C++ CGP Q CH+HA C G A C C G+
Sbjct: 801 NRIDSDGACLTGTCRDGSAGRLCDKQTSACGP--YVQFCHIHATCEYSNGTASCICKAGY 858
Query: 853 EGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGRVCVAIDECELDM 912
EGDG C+ +PC+ GGCS NAEC+ GTH C C +GW+G+GR C I+ C L
Sbjct: 859 EGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCSEINNCLLPS 918
Query: 913 RGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQR 972
GGCH +A C YVGPGQ+ C CK GF G+G C PI C G CH LA+C++ G
Sbjct: 919 AGGCHDNASCLYVGPGQNECECKKGFRGNGIDCEPITSCLEQTGKCHPLASCQSTSSGVW 978
Query: 973 VCTCPPGFGGDGFSCYGDIFRELEANAHFSIFYQWLKSAGI--TLPADRRVTALVPSEAA 1030
C C G+ GDGF CYG+ EL + +IF +W+ +A + TL A +T LVPS+ A
Sbjct: 979 SCVCQEGYEGDGFLCYGNAAVELSFLSEAAIFNRWINNASLQPTLSATSNLTVLVPSQQA 1038
Query: 1031 VRQLSPEDRAFWLQPRTLPNLVRAHFLQGALFEEELARLGGQEV-ATLNPTTRWEIRNIS 1089
+ ++++FWL +P L++ H L G +L L ++ AT + +
Sbjct: 1039 TEDMDQDEKSFWLSQSNIPALIKYHMLLGTYRVADLQTLSSSDMLATSLQGNFLHLAKVD 1098
Query: 1090 GRVWVQNASVDVADLLATNGVLHILSQVLLPPRGDVPGGQGLLQQLDLVPAFSLFRELLQ 1149
G + ++ AS+ D ATNGV+HI+++VL+P R LL +L+ +P +S+FR +
Sbjct: 1099 GNITIEGASIVDGDNAATNGVIHIINKVLVPQRRLTGSLPNLLMRLEQMPDYSIFRGYII 1158
Query: 1150 HHGLVPQIEAATAYTIFVPTNRSLE---AQGNSSHLDADTVRHHVVLGEALSMETLRKGG 1206
+ L IEAA AYT+F P N ++E + L+ D +R+HVVL E L L G
Sbjct: 1159 QYNLANAIEAADAYTVFAPNNNAIENYIREKKVLSLEEDVLRYHVVLEEKLLKNDLHNGM 1218
Query: 1207 HRNSLLGPAHWIVFYNHSGQPEVNHVPLEGPMLEAPGRSLIGLSGVLTVGSSRCLHSHAE 1266
HR ++LG ++++ F+ H+ Q VN P+ + + GL VL + +RC ++
Sbjct: 1219 HRETMLGFSYFLSFFLHNDQLYVNEAPINYTNVATDKGVIHGLGKVLEIQKNRCDNNDTT 1278
Query: 1267 ALREKCVNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSR----GCSYTCAKKIQVPDCCP 1322
+R +C C+ C G + ++ C+Y S F R GC C + + +CC
Sbjct: 1279 IIRGRCRTCSSELTCPFGTKSLGNEKRRCIYTSYFMGRRTLFIGCQPKCVRTVITRECCA 1338
Query: 1323 GFFGTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCTGV 1382
GFFG C+PCPG VC G+G C D G+G C C EGF GTACE C G+YG +C
Sbjct: 1339 GFFGPQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHCDQA 1398
Query: 1383 CDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTCAC 1442
C C HG C +G GDGSC C+VGW+G+ CD T C C +ANC+ +S G ++C C
Sbjct: 1399 CSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTASCKC 1458
Query: 1443 AAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINSCL 1502
AAG+ GNG C+ ++ C +GGCS A+C + PG+R CTC+ GY GDG +C EIN CL
Sbjct: 1459 AAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEINPCL 1518
Query: 1503 IHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKSTGD 1562
+HGGC +AEC TGP Q +C+C Y+GDG + C L++ C NGGCS +A C TG
Sbjct: 1519 ENHGGCDKNAECTQTGPNQAACNCLPAYTGDG-KVCTLINVCLTKNGGCSEFAICNHTGQ 1577
Query: 1563 GQRTCTCDTAHTVGDGLTCRARVGLELLRDKHASFFSLRLLEY--KELKGDGPFTIFVPH 1620
+RTCTC + +GDG TCR + EL ++ S + +L E+ K+L G GPFT+F P
Sbjct: 1578 VERTCTCKPNY-IGDGFTCRGSIYQELPKNPKTSQYFFQLQEHFVKDLVGPGPFTVFAP- 1635
Query: 1621 ADLMSNLSQDELARIRAHRQL-----VFRYHVVGCRRLRSEDLLEQGYATALSGHPLRFS 1675
+ + DE AR++ + V RYHVV C +L E+L AT+L G P+ S
Sbjct: 1636 ----LSAAFDEEARVKDWDKYGLMPQVLRYHVVACHQLLLENLKLISNATSLQGEPIVIS 1691
Query: 1676 EREGSIYLNDFARVVSSDHEAVNGILHFIDRVLLPPEALHWEPDDAPIPRRNVTAAAQGF 1735
+ ++Y+N+ A+++SSD + NGI+H ID++L P L D++ +N+T A
Sbjct: 1692 VSQSTVYINNKAKIISSDIISTNGIVHIIDKLLSPKNLLITPKDNSGRILQNLTTLATNN 1751
Query: 1736 GYKIFSGLLKVAGLLPLLREASHRPFTMLWPTDAAFRALPPDRQAWLYHEDHRDKLAAIL 1795
GY FS L++ +GLL ++ + H P T+ WPTD A ALP ++Q +L+++D++DKL L
Sbjct: 1752 GYIKFSNLIQDSGLLSVITDPIHTPVTLFWPTDQALHALPAEQQDFLFNQDNKDKLKEYL 1811
Query: 1796 RGHMIRNVEALASDLPNLGPLRTMHGTPISFSCSRTR-AGELMVGEDDARIVQRHLPFEG 1854
+ H+IR+ + LA DLP +T+ G+ +S C R G+L + RIVQR L F+
Sbjct: 1812 KFHVIRDAKVLAVDLPTSTAWKTLQGSELSVKCGAGRDIGDLFLNGQTCRIVQRELLFDL 1871
Query: 1855 GLAYGIDQLLEPPGLGARCDHFETRPLRLNTCSICGLEPPCPEGSQEQGSPEACWRFYPK 1914
G+AYGID LL P LG RCD F T C C P CP S+ +G + C
Sbjct: 1872 GVAYGIDCLLIDPTLGGRCDTFTTFDAS-GECGSCVNTPSCPRWSKPKGVKQKC------ 1924
Query: 1915 FWTSPPLHSLGLRSVWVHPSLWGRPQGLGRGCHRNCVTTTWKPSCCPGHYGSECQACPGG 1974
+ P +L GC C P CC G++G +CQACPGG
Sbjct: 1925 LYNLPFKRNL-------------------EGCRERCSLVIQIPRCCKGYFGRDCQACPGG 1965
Query: 1975 PSSPCSDRGVCMDGMSGSGQCLCRSGFAGTACELCAPGAFGPHCQACRCTVHGRCDEGLG 2034
P +PC++RGVC+D S +G+C C +GF GTACE+C PG FGP C C C+ HG+CD+G+
Sbjct: 1966 PDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPDCLPCGCSDHGQCDDGIT 2025
Query: 2035 GSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEAVCRAGNSCECSLGYEGDGRVCTVADL 2094
GSG C C+ GWTGP C+ Q L VCTPPC+ A C+ N+CEC+L YEGDG CTV D
Sbjct: 2026 GSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKENNTCECNLDYEGDGITCTVVDF 2085
Query: 2095 CQDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWSCRARNPCTDGHRGGCSEHANCLSTG 2154
C+ +GGC++ A CSQ GT V+C+C Y+GDG SC +PC DG GGC EHA C TG
Sbjct: 2086 CKQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGHSCTEIDPCADGLNGGCHEHATCKMTG 2145
Query: 2155 LNTRRCECHAGYVGDGLQCLEESEPPVDRCLGQPPPCHSDAMCTDLHFQEKRAGVFHLQA 2214
+CEC + YVGDGL C E + P+DRCL CH+DA C DLHFQ+ GVFHL++
Sbjct: 2146 PGKHKCECKSHYVGDGLNC-EPEQLPIDRCLQDNGQCHADAKCVDLHFQDTTVGVFHLRS 2204
Query: 2215 TSGPYGLNFSEAEAACEAQGAVLASFPQLSAAQQLGFHLCLMGWLANGSTAHPVVFPVAD 2274
G Y L F +A AC + A +A++ QLS AQ+ +HLC GWL G A+P F +
Sbjct: 2205 PLGQYKLTFDKAREACANEAATMATYNQLSYAQKAKYHLCSAGWLETGRVAYPTAFASQN 2264
Query: 2275 CGNGRVGIVSLGARKNLSERWDAYCFRVQDVACRCRNGFVGDGISTCNGKLLDVLAATAN 2334
CG+G VGIV G R N SE WD +C+R++DV C C+ G+VGDG S C+G LL VL + +
Sbjct: 2265 CGSGVVGIVDYGPRPNKSEMWDVFCYRMKDVNCTCKVGYVGDGFS-CSGNLLQVLMSFPS 2323
Query: 2335 FSTFYGMLLGYANATQRGLDFLDFLDDELTYKTLFVPVNEGFVDNMTLSGPDLELHASNA 2394
+ F +L Y+N++ RG FL+ L D TLFVP N G +N TLSG D+E H +N
Sbjct: 2324 LTNFLTEVLAYSNSSARGRAFLEHLTDLSIRGTLFVPQNSGLGENETLSGRDIEHHLANV 2383
Query: 2395 TLLSAN-ASQGKLLPAHSGLSLIISDAGPDNSSWAPVAPGTVVVSRIIVWDIMAFNGIIH 2453
++ N G L G L+I+ P V I+ WDI A NGIIH
Sbjct: 2384 SMFFYNDLVNGTTLQTRLGSKLLIT---ASQDPLQPTETRFVDGRAILQWDIFASNGIIH 2440
Query: 2454 ALASPLLAPPQPQAVLAPEAPPVAAGVGAVLAAGALLGLVAGALYLRARGKPMGFGFSAF 2513
++ PL APP P + G G A + G VA A Y R GF F
Sbjct: 2441 VISRPLKAPPAPVTL-----THTGLGAGIFFAIILVTGAVALAAYSYFRINRRTIGFQHF 2495
Query: 2514 QAEDDADDDFSPWQEGTNPTLVSVPNPVFGSDTFC------EPFDDS 2554
++E+D + Q+ N + NP++ S T +PF DS
Sbjct: 2496 ESEEDINVAALGKQQPEN-----ISNPLYESTTSAPPEPSYDPFTDS 2537
Score = 801 bits (2070), Expect = 0.0
Identities = 518/1627 (31%), Positives = 775/1627 (47%), Gaps = 164/1627 (10%)
Query: 652 KHCSEEQHKIVAGSCVDCQALNTST-CPPNSVKL---DIFPKECVYIHDPTGLNVLKKGC 707
+ C + + C C ALN CP + + ++C Y + ++ GC
Sbjct: 29 RRCDRKSLLTIRTECRSC-ALNLGVKCPDGYTMITSGSVGVRDCRYTFEVRTYSLSLPGC 87
Query: 708 ASYCNQTIMEQGCCKGFFGPDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIAC 767
C + ++ CC G +GPDC +CPGG +PC G+G+C++G++GNG C C + G AC
Sbjct: 88 RHICRKDYLQPRCCPGRWGPDCIECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTAC 147
Query: 768 HICSNPNKHGEQCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGL 827
C++ N G C C CVHG+C++ G C+ C ++G C++ + +C
Sbjct: 148 ETCADDNLFGPSCSSVCNCVHGVCNSGLDGDGTCE---CYSAYTGPKCDKPIPECA---- 200
Query: 828 AQHCHLHARC---VSQEGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSL 884
A C ++RC E C+CL + GDG C P NPC R C +A C
Sbjct: 201 ALLCPENSRCSPSTEDENKLECKCLPNYRGDGKYCDPINPCL---RKICHPHAHCTYLGP 257
Query: 885 GTHHCTCHKGWSGDGRVCVAIDECELDMRGGCHTDA-LCSYVGPGQSRCTCKLGFAG--D 941
H CTC +G+ GDG+VC+ +D C+++ G C T + +C Y GPGQS C CK +
Sbjct: 258 NRHSCTCQEGYRGDGQVCLPVDPCQINF-GNCPTKSTVCKYDGPGQSHCECKEHYQNFVP 316
Query: 942 GYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGFGGDGFSCYGDIFREL-EANAH 1000
G CS D C++ N CH A C V G+ C C G+ GDG +CYG+I L E N
Sbjct: 317 GVGCSMTDICKSDNP-CHRNANCTTVAPGRTECICQKGYVGDGLTCYGNIMERLRELNTE 375
Query: 1001 FSIFYQWLKSAGITL-------PADRR--VTALVPSEAAVRQLSPEDRAFWLQPRTLPNL 1051
+Q ++ I+L P + T L+P++ ++ + + + +
Sbjct: 376 PRGKWQGRLTSFISLLDKAYAWPLSKLGPFTVLLPTDKGLKGFNVNE--LLVDNKAAQYF 433
Query: 1052 VRAHFLQGALFEEELAR------LGGQ--EVATLNPTTRWEIRNISGRVWVQNASVDVAD 1103
V+ H + G + E + L G+ E+ + + +++ G+ + + D
Sbjct: 434 VKLHIIAGQMNIEYMNNTDMFYTLTGKSGEIFNSDKDNQIKLKLHGGK---KKVKIIQGD 490
Query: 1104 LLATNGVLHILSQVL--LPPRGDVPGGQGLLQQLDLVPAFSLFRELLQHHGLVPQIE--- 1158
++A+NG+LHIL + + L P + Q ++ L P +S FR LL+ L ++
Sbjct: 491 IIASNGLLHILDRAMDKLEPTFESNNEQTIMTMLQ--PRYSKFRSLLEETNLGHALDEDG 548
Query: 1159 AATAYTIFVPTNRSLE--AQGNSSHLDA--------DTVRHHVVLGEALSMETLRKGGHR 1208
YTIFVP N +L G +L + + VR+H+V L + TL H
Sbjct: 549 VGGPYTIFVPNNEALNNMKDGTLDYLLSPEGSRKLLELVRYHIVPFTQLEVATLISTPHI 608
Query: 1209 NSLLGPAHWIVFYN--HSGQPEVNHVPLEGPMLEAPGRSLIGLSGVLTVGS------SRC 1260
S+ A+ ++ +N +GQ N V +E + A + L+GVL S RC
Sbjct: 609 RSM---ANQLIQFNTTDNGQILANDVAMEEIEITAKNGRIYTLTGVLIPPSIVPILPHRC 665
Query: 1261 LHSHAEALREKCVNCTRRF--RCTQGFQLQDTPRKSCVYRSGF-SFSRGCSYTCAKKIQV 1317
+ E CV+C+ + RC + CVY F S GC+ C +++
Sbjct: 666 DETKREMKLGTCVSCSLVYWSRCPANSEPTALFTHRCVYSGRFGSLKSGCARYCNATVKI 725
Query: 1318 PDCCPGFFGTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVC-ELGRYG 1376
P CC GF+G C CPGG CSG+GQC D G+G C C EGF G+ C+ C + +YG
Sbjct: 726 PKCCKGFYGPDCNQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYG 785
Query: 1377 PNCTGVCDCAHGLCQEGLQGDGSCV---CNVGWQGLRCDQKITSPQCP--RKCDPNANCV 1431
P C C C HG C + DG+C+ C G G CD++ TS P + C +A C
Sbjct: 786 PRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQ-TSACGPYVQFCHIHATC- 843
Query: 1432 QDSAGASTCACAAGYSGNGIFCSEVDPCAH-GHGGCSPHANCTKVAPGQRTCTCQDGYMG 1490
+ S G ++C C AGY G+G CSE+DPC GGCS +A C K G TC CQ G+ G
Sbjct: 844 EYSNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTG 903
Query: 1491 DGELCQEINSCLIHH-GGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLDPCSKNNG 1549
+G C EIN+CL+ GGCH +A C+ GP Q C C++G+ G+GI CE + C + G
Sbjct: 904 NGRDCSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGI-DCEPITSCLEQTG 962
Query: 1550 GCSPYATCKSTGDGQRTCTCDTAHTVGDGLTCRARVGLELLRDKHASFFSLRLLEYK--- 1606
C P A+C+ST G +C C + GDG C +EL A+ F+ +
Sbjct: 963 KCHPLASCQSTSSGVWSCVCQEGYE-GDGFLCYGNAAVELSFLSEAAIFNRWINNASLQP 1021
Query: 1607 ELKGDGPFTIFVPHADLMSNLSQDE---------LARIRAHRQLVFRYHVVGCRRLRSED 1657
L T+ VP ++ QDE + + + L+ Y V + L S D
Sbjct: 1022 TLSATSNLTVLVPSQQATEDMDQDEKSFWLSQSNIPALIKYHMLLGTYRVADLQTLSSSD 1081
Query: 1658 LLEQGYATALSGHPLRFSEREGSIYLNDFARVVSSDHEAVNGILHFIDRVLLPPEALHWE 1717
+L AT+L G+ L ++ +G+I + A +V D+ A NG++H I++VL+P L
Sbjct: 1082 ML----ATSLQGNFLHLAKVDGNITIEG-ASIVDGDNAATNGVIHIINKVLVPQRRL--- 1133
Query: 1718 PDDAPIPRRNVTAAAQGFGYKIFSGLLKVAGLLPLLREASHRPFTMLWPTDAAFRALPPD 1777
+P + Q Y IF G + L + A +T+ P + A +
Sbjct: 1134 --TGSLPNL-LMRLEQMPDYSIFRGYIIQYNLANAIEAAD--AYTVFAPNNNAIENYIRE 1188
Query: 1778 RQAWLYHEDHRDKLAAILRGHMIRNVEALASDLPNLGPLRTMHGTPISFSCSRTRAGELM 1837
++ ED +LR H++ + L +DL N TM G S +L
Sbjct: 1189 KKVLSLEED-------VLRYHVVLEEKLLKNDLHNGMHRETMLGFSYFLSFF-LHNDQLY 1240
Query: 1838 VGEDDARIVQRHLPFEGGLAYGIDQLLEPPGLGARCDHFETRPLRLNTCSICGLEPPCPE 1897
V E A I ++ + G+ +G+ ++LE RCD+ +T +R C C E CP
Sbjct: 1241 VNE--APINYTNVATDKGVIHGLGKVLEIQK--NRCDNNDTTIIR-GRCRTCSSELTCPF 1295
Query: 1898 GSQEQGSPEACWRFYPKFWTSPPLHSLGLRSVWVHPSLWGRPQGLGRGCHRNCVTTTWKP 1957
G++ G+ + + F +G R++++ GC CV T
Sbjct: 1296 GTKSLGNEKRRCIYTSYF--------MGRRTLFI-------------GCQPKCVRTVITR 1334
Query: 1958 SCCPGHYGSECQACPGGPSSPCSDRGVCMDGMSGSGQCLCRSGFAGTACELCAPGAFGPH 2017
CC G +G +CQ CPG + C G+C+DG++G+G C C GF+GTACE C G +G H
Sbjct: 1335 ECCAGFFGPQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIH 1394
Query: 2018 C-QACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEAVCRAGN-- 2074
C QAC C VHGRC++G G GSC CD GW G C+ + C C A C +
Sbjct: 1395 CDQACSC-VHGRCNQGPLGDGSCDCDVGWRGVHCD-NATTEDNCNGTCHTSANCLTNSDG 1452
Query: 2075 --SCECSLGYEGDGRVCTVADLCQDGHGGCSEHANCSQV--GTMVTCTCLPDYEGDGWSC 2130
SC+C+ G++G+G +CT + C+ +GGCS A+C + G V CTC Y GDG C
Sbjct: 1453 TASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRV-CTCKAGYTGDGIVC 1511
Query: 2131 RARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGDGLQCLEESEPPVDRCLGQPPP 2190
NPC + H GGC ++A C TG N C C Y GDG C ++ CL +
Sbjct: 1512 LEINPCLENH-GGCDKNAECTQTGPNQAACNCLPAYTGDGKVC-----TLINVCLTKNGG 1565
Query: 2191 CHSDAMC 2197
C A+C
Sbjct: 1566 CSEFAIC 1572
>gi|26051243 tumor necrosis factor, alpha-induced protein 6 precursor
[Homo sapiens]
Length = 277
Score = 117 bits (292), Expect = 2e-25
Identities = 50/104 (48%), Positives = 70/104 (67%)
Query: 2204 EKRAGVFHLQATSGPYGLNFSEAEAACEAQGAVLASFPQLSAAQQLGFHLCLMGWLANGS 2263
E+ AGV+H +A SG Y L ++EA+A CE +G LA++ QL AA+++GFH+C GW+A G
Sbjct: 32 ERAAGVYHREARSGKYKLTYAEAKAVCEFEGGHLATYKQLEAARKIGFHVCAAGWMAKGR 91
Query: 2264 TAHPVVFPVADCGNGRVGIVSLGARKNLSERWDAYCFRVQDVAC 2307
+P+V P +CG G+ GI+ G R N SERWDAYC+ C
Sbjct: 92 VGYPIVKPGPNCGFGKTGIIDYGIRLNRSERWDAYCYNPHAKEC 135
>gi|126091152 cubilin [Homo sapiens]
Length = 3623
Score = 114 bits (285), Expect = 1e-24
Identities = 86/272 (31%), Positives = 119/272 (43%), Gaps = 37/272 (13%)
Query: 737 SNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQCQEDCG----CVHG-LC 791
SNPC G C + + + C+C P +KG C N +C+ G C +G C
Sbjct: 138 SNPCQNGGTCLN-LHDSFFCICPPQWKGPLCSADVN------ECEIYSGTPLSCQNGGTC 190
Query: 792 DNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQEGVAR----CR 847
N GS C C P G C DC +A+ H + +E C
Sbjct: 191 VNTMGSYS-CH---CPPETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCV 246
Query: 848 CLDGFEGDGFSCTPSNPCSHPDR-------GGCSENAECVPGSLGTHHC-TCHKGWSGDG 899
C G+ +P++P DR G CS +C + G+ +C C GW G+G
Sbjct: 247 C-----DAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCF-NTQGSFYCGACPTGWQGNG 300
Query: 900 RVCVAIDECELDMRGGCHTDALCSYVG-PGQSRC-TCKLGFAGDGYQCSPIDPCRAGNGG 957
+C I+ECE++ GGC V PG S C C G+ GDG C+ D C NGG
Sbjct: 301 YICEDINECEIN-NGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGG 359
Query: 958 CHGLATCRAVGGGQRVCTCPPGFGGDGFSCYG 989
CH A+C + G +CTC PG+ G+G+ G
Sbjct: 360 CHPDASCSSTLGSLPLCTCLPGYTGNGYGPNG 391
Score = 113 bits (282), Expect = 3e-24
Identities = 89/267 (33%), Positives = 120/267 (44%), Gaps = 42/267 (15%)
Query: 1339 VCSGHGQCQDRFLGSGEC-HCHEGFHGTACEVCELGRYGPNCTG---VCDCAHGL---CQ 1391
VCS + CQ+ G C + H+ F C +C GP C+ C+ G CQ
Sbjct: 135 VCSSN-PCQN----GGTCLNLHDSFF---C-ICPPQWKGPLCSADVNECEIYSGTPLSCQ 185
Query: 1392 EGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPN-----ANCV--------QDSAGAS 1438
G G+CV +G C + PQC K D A CV ++ AG
Sbjct: 186 NG----GTCVNTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEP 241
Query: 1439 --TCACAAG--YSGNGIFCS-EVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGE 1493
+C C AG +S N C+ + D C+ G CS C C G+ G+G
Sbjct: 242 KYSCVCDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGY 301
Query: 1494 LCQEINSCLIHHGGCHIH--AECIPTGPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGC 1551
+C++IN C I++GGC + EC+ T +C GY GDG R C L D CS +NGGC
Sbjct: 302 ICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQGDG-RVCTLTDICSVSNGGC 360
Query: 1552 SPYATCKSTGDGQRTCTCDTAHTVGDG 1578
P A+C ST CTC +T G+G
Sbjct: 361 HPDASCSSTLGSLPLCTCLPGYT-GNG 386
Score = 99.0 bits (245), Expect = 5e-20
Identities = 95/349 (27%), Positives = 137/349 (39%), Gaps = 82/349 (23%)
Query: 1894 PCPEGSQEQGSPEACWRFYPKFWTSPPLHSLGLRSVWVHPSLWGRPQGLGRGCHRNCVTT 1953
PC G ++ + P W P L S + ++ G P G CV T
Sbjct: 140 PCQNGGTCLNLHDSFFCICPPQWKGP-LCSADVNECEIYS---GTPLSCQNG--GTCVNT 193
Query: 1954 TWKPSC-CPGH-YGSECQA----CPGGPSSPCSDRGVCMDGMSGSG-----QCLCRSGFA 2002
SC CP YG +C + C GG + C G+C D M C+C +G+
Sbjct: 194 MGSYSCHCPPETYGPQCASKYDDCEGGSVARCV-HGICEDLMREQAGEPKYSCVCDAGWM 252
Query: 2003 GTACELCAPGAFGPHCQACR------------CTVHGRCDEGLGGSGSCFCDEGWTGP-- 2048
F P+ AC C+ +C G C GW G
Sbjct: 253 -----------FSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGY 301
Query: 2049 ------RCEVQLELQPVCTPPCAPEAVCRAGNS-CE-CSLGYEGDGRVCTVADLCQDGHG 2100
CE+ C+ E V G+S C+ C GY+GDGRVCT+ D+C +G
Sbjct: 302 ICEDINECEIN---NGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNG 358
Query: 2101 GCSEHANCSQ-VGTMVTCTCLPDYEGDGWSCRA---------RNPCTDGHRGGCSEHANC 2150
GC A+CS +G++ CTCLP Y G+G+ +PC +G C
Sbjct: 359 GCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNG---------QC 409
Query: 2151 LSTGLNTRRCECHAGYVGDGLQCLEESEPPVDRCLGQPPPCHSDAMCTD 2199
+ T ++ C+C +G+ G+ C E ++ CL PC + C D
Sbjct: 410 IDT-VSGYFCKCDSGWT--GVNCTEN----INECLSN--PCLNGGTCVD 449
Score = 91.3 bits (225), Expect = 1e-17
Identities = 122/456 (26%), Positives = 175/456 (38%), Gaps = 106/456 (23%)
Query: 1174 EAQGNSSHLDADTVRHHVVLGEALSMETLRKGGHRNSLLGPAHWIVFYNHS-GQPEVNHV 1232
E G + L+ + + L + M T R G+ L G A I F S G+ ++N
Sbjct: 20 EVNGEAGELELQRQKRSINLQQP-RMATER--GNLVFLTGSAQNIEFRTGSLGKIKLNDE 76
Query: 1233 PLEGPM--LEAPGRSLIGLSGVLTVGSSRCLHSHAEALREKCVNCTRRFRCTQGFQLQDT 1290
L + ++ +I L G +G + + S L K V+ R+F QG Q Q
Sbjct: 77 DLSECLHQIQKNKEDIIELKGS-AIGLPQNISSQIYQLNSKLVDLERKF---QGLQ-QTV 131
Query: 1291 PRKSC----VYRSGFSFSRGCSYTCAKKIQVPDCCPGFFGTLCEP----CP--GGLGGVC 1340
+K C G + S+ C C P + G LC C G C
Sbjct: 132 DKKVCSSNPCQNGGTCLNLHDSFFCI-------CPPQWKGPLCSADVNECEIYSGTPLSC 184
Query: 1341 SGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCTG--VCDCAHGLCQEGLQGDG 1398
G C + +GS CHC +G C +Y +C G V C HG+C++ ++
Sbjct: 185 QNGGTCVNT-MGSYSCHCPPETYGPQCA----SKYD-DCEGGSVARCVHGICEDLMREQA 238
Query: 1399 -----SCVCNVGWQ--------GLRCDQKITSP-------------------QCP----- 1421
SCVC+ GW L D+ P CP
Sbjct: 239 GEPKYSCVCDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQG 298
Query: 1422 --------RKCD---------PNANCVQDSAGASTC-ACAAGYSGNGIFCSEVDPCAHGH 1463
+C+ P CV ++ G+S C AC GY G+G C+ D C+ +
Sbjct: 299 NGYICEDINECEINNGGCSVAPPVECV-NTPGSSHCQACPPGYQGDGRVCTLTDICSVSN 357
Query: 1464 GGCSPHANCTKVAPGQRTCTCQDGYMGDG----ELCQEINSCLIHHGGCHIHAECIPTGP 1519
GGC P A+C+ CTC GY G+G Q N CL H C ++ +CI T
Sbjct: 358 GGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSH--PC-LNGQCIDT-V 413
Query: 1520 QQVSCSCREGYSG----DGIRTCELLDPCSKNNGGC 1551
C C G++G + I C L +PC N G C
Sbjct: 414 SGYFCKCDSGWTGVNCTENINEC-LSNPC-LNGGTC 447
Score = 82.8 bits (203), Expect = 4e-15
Identities = 72/268 (26%), Positives = 97/268 (36%), Gaps = 55/268 (20%)
Query: 101 CPGYW-GSRC----HECPGGAETP--CNGHGTCLDGMDRNGTCVCQENFRGSACQECQDP 153
CP W G C +EC + TP C GTC++ M + +C C G C D
Sbjct: 158 CPPQWKGPLCSADVNECEIYSGTPLSCQNGGTCVNTMG-SYSCHCPPETYGPQCASKYD- 215
Query: 154 NRFGPDCQ--SVCSCVHGVCNHGPRGDG-----SCLCFAGYTGPHCDQELPVCQELRCPQ 206
DC+ SV CVHG+C R SC+C AG+ + P
Sbjct: 216 -----DCEGGSVARCVHGICEDLMREQAGEPKYSCVCDAGW--------------MFSPN 256
Query: 207 NTQCSAEAPSCRCLPGYTQQGSECRAPNPCWPSPCSLLAQCSVSPKGQAQCH-CPENYHG 265
+ C+ + C PG PCS L QC + +G C CP + G
Sbjct: 257 SPACTLDRDECSFQPG-----------------PCSTLVQC-FNTQGSFYCGACPTGWQG 298
Query: 266 DGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFC-TCRPGLVSINSNASAGCFAFCSPF 324
+G +C + C N GGC + PG + C C PG + S
Sbjct: 299 NGYICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNG 358
Query: 325 SCDRSATCQVTADGKTSCVCRESEVGDG 352
C A+C T C C G+G
Sbjct: 359 GCHPDASCSSTLGSLPLCTCLPGYTGNG 386
Score = 60.1 bits (144), Expect = 3e-08
Identities = 86/340 (25%), Positives = 124/340 (36%), Gaps = 75/340 (22%)
Query: 664 GSCVDCQALNTSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKGCASYCNQTIMEQG---- 719
G+CV+ + CPP + + +C +D + + C + EQ
Sbjct: 188 GTCVNTMGSYSCHCPPET-----YGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPK 242
Query: 720 ----CCKGF-FGPDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNP- 773
C G+ F P+ C + G CS +Q CF C C
Sbjct: 243 YSCVCDAGWMFSPNSPACTLDRDECSFQPGPCSTLVQ------CFNTQGSFYCGACPTGW 296
Query: 774 NKHGEQCQE--DCGCVHGLCD--------NRPGSGGVCQQGTCAPGFSGR--------FC 815
+G C++ +C +G C N PGS CQ C PG+ G C
Sbjct: 297 QGNGYICEDINECEINNGGCSVAPPVECVNTPGSSH-CQ--ACPPGYQGDGRVCTLTDIC 353
Query: 816 NESMGDCGPTGLAQHCHLHARCVSQEG-VARCRCLDGFEGDGFS---CTP-SNPC-SHPD 869
+ S G C P A C S G + C CL G+ G+G+ C SN C SHP
Sbjct: 354 SVSNGGCHPD---------ASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHP- 403
Query: 870 RGGCSENAECVPGSLGTHHCTCHKGWSGDGRVCVA-IDECELD--MRGGCHTDALCSYVG 926
N +C+ G + C C GW+G C I+EC + + GG D + S+
Sbjct: 404 ----CLNGQCIDTVSG-YFCKCDSGWTGVN--CTENINECLSNPCLNGGTCVDGVDSF-- 454
Query: 927 PGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRA 966
C C + G Q P C G +G + R+
Sbjct: 455 ----SCECTRLWTGALCQV-PQQVCGESLSGINGSFSYRS 489
Score = 44.3 bits (103), Expect = 0.002
Identities = 48/197 (24%), Positives = 73/197 (37%), Gaps = 36/197 (18%)
Query: 55 CPSGWLRELPDQITQDCRY-EVQLGGSMVSMSGCRRKCRKQVVQKACCPGYWGSR----- 108
CP+GW I +D E+ GG V+ +AC PGY G
Sbjct: 292 CPTGWQGN--GYICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVCTL 349
Query: 109 ---CHECPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPD----CQ 161
C GG C+ +C + C C + G N +GP+
Sbjct: 350 TDICSVSNGG----CHPDASCSSTLGSLPLCTCLPGYTG---------NGYGPNGCVQLS 396
Query: 162 SVC---SCVHGVCNHGPRGDGSCLCFAGYTGPHCDQELPVCQELRCPQNTQC--SAEAPS 216
++C C++G C G C C +G+TG +C + + C C C ++ S
Sbjct: 397 NICLSHPCLNGQCIDTVSGY-FCKCDSGWTGVNCTENINECLSNPCLNGGTCVDGVDSFS 455
Query: 217 CRCLPGYTQQGSECRAP 233
C C +T G+ C+ P
Sbjct: 456 CECTRLWT--GALCQVP 470
Score = 42.4 bits (98), Expect = 0.006
Identities = 42/129 (32%), Positives = 55/129 (42%), Gaps = 26/129 (20%)
Query: 1945 GCH--RNCVTTTWKP---SCCPGHYGSECQACPGGP--------SSPCSDRGVCMDGMSG 1991
GCH +C +T +C PG+ G+ P G S PC + G C+D +SG
Sbjct: 359 GCHPDASCSSTLGSLPLCTCLPGYTGNGYG--PNGCVQLSNICLSHPCLN-GQCIDTVSG 415
Query: 1992 SGQCLCRSGFAGTACELCAPGAFGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCE 2051
C C SG+ G C C + C G C +G+ S SC C WTG C+
Sbjct: 416 YF-CKCDSGWTGVNCTENIN-----ECLSNPCLNGGTCVDGVD-SFSCECTRLWTGALCQ 468
Query: 2052 VQLELQPVC 2060
V Q VC
Sbjct: 469 VP---QQVC 474
Score = 33.5 bits (75), Expect = 2.8
Identities = 23/88 (26%), Positives = 34/88 (38%), Gaps = 8/88 (9%)
Query: 720 CCKGFFGPDCTQCPGG-FSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGE 778
C G+ G +CT+ SNPC G C DG+ + +C C + G C + +
Sbjct: 420 CDSGWTGVNCTENINECLSNPCLNGGTCVDGVD-SFSCECTRLWTGALCQVPQ------Q 472
Query: 779 QCQEDCGCVHGLCDNRPGSGGVCQQGTC 806
C E ++G R G C
Sbjct: 473 VCGESLSGINGSFSYRSPDVGYVHDVNC 500
Score = 33.1 bits (74), Expect = 3.6
Identities = 45/177 (25%), Positives = 63/177 (35%), Gaps = 34/177 (19%)
Query: 53 QTCPSGW--------LRELPDQITQDCRYEVQLGGSMVSMSGCRRKCRKQVVQKACCPGY 104
Q CP G+ L ++ C + ++ S+ C C PGY
Sbjct: 334 QACPPGYQGDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLC-----------TCLPGY 382
Query: 105 WGSRCHECPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDC-QSV 163
G+ P G N CL NG C+ + G C+ C D G +C +++
Sbjct: 383 TGNGYG--PNGCVQLSN---ICLSHPCLNGQCI--DTVSGYFCK-C-DSGWTGVNCTENI 433
Query: 164 CSCVHGVC-NHGPRGDG----SCLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAP 215
C+ C N G DG SC C +TG C VC E N S +P
Sbjct: 434 NECLSNPCLNGGTCVDGVDSFSCECTRLWTGALCQVPQQVCGESLSGINGSFSYRSP 490
>gi|24430141 fibrillin 1 precursor [Homo sapiens]
Length = 2871
Score = 113 bits (283), Expect = 2e-24
Identities = 100/348 (28%), Positives = 146/348 (41%), Gaps = 64/348 (18%)
Query: 1271 KCVNCTRRFRCTQGFQLQDTP-RKSCVYRSGFSFSRG-CSYTCAKKIQVPDC-CPGFFGT 1327
+CVN +++C TP R CV S G C C +C C F
Sbjct: 1170 RCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFAL 1229
Query: 1328 L-----------CEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHG-----TACEV-- 1369
+ CE P +C G GQC + G C C++GF T +V
Sbjct: 1230 MPDQRSCTDIDECEDNPN----ICDG-GQCTN-IPGEYRCLCYDGFMASEDMKTCVDVNE 1283
Query: 1370 CELGRYGPNCTGVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITS-PQCP---RKCD 1425
C+L PN C G C E +G C C++G+ G + T +C C
Sbjct: 1284 CDLN---PNI-----CLSGTC-ENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCG 1334
Query: 1426 PNANCVQDSAGASTCACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQ 1485
+A C ++AG+ C+C+ G+ G+GI C+++D C++G CS HA+C K G C C+
Sbjct: 1335 KHAVCT-NTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADC-KNTMGSYRCLCK 1392
Query: 1486 DGYMGDGELCQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGY--SGDGIRTCELLDP 1543
+GY GDG C +++ C + C + +C+ P C C G+ S DG + CE +D
Sbjct: 1393 EGYTGDGFTCTDLDECSENLNLCG-NGQCL-NAPGGYRCECDMGFVPSADG-KACEDIDE 1449
Query: 1544 CSKNNGGCSPYATCKSTGDGQRTCTCDTAHTVGDGLTCRARVGLELLR 1591
CS N C T H + C +G EL R
Sbjct: 1450 CSLPN-----------------ICVFGTCHNLPGLFRCECEIGYELDR 1480
Score = 102 bits (253), Expect = 6e-21
Identities = 112/431 (25%), Positives = 158/431 (36%), Gaps = 104/431 (24%)
Query: 623 QRVDVMAANGVIHMLDGIL---------LPPTILPILP-KHCSEEQHKIVAGSCVDCQAL 672
QR ++ GV H +G L P I + C H G CV+
Sbjct: 1118 QRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGK 1177
Query: 673 NTSTCPP--NSVKLDIFPKECVYIHDPTGLNVLKKGCASYCNQT--IMEQGCCKGF-FGP 727
C P +S +F CV I + +++ GC ++C + E C GF P
Sbjct: 1178 YQCACNPGYHSTPDRLF---CVDIDE---CSIMNGGCETFCTNSEGSYECSCQPGFALMP 1231
Query: 728 D---CTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIA-CHICSNPNKHGEQCQED 783
D CT NP G I G CLC+ + C + N +C +
Sbjct: 1232 DQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVN----ECDLN 1287
Query: 784 CG-CVHGLCDNRPGSGGVCQQGTCAPGFSGR-----------------------FCNESM 819
C+ G C+N GS +C C G+SG+ C +
Sbjct: 1288 PNICLSGTCENTKGSF-ICH---CDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTA 1343
Query: 820 GD----CGPTGLAQH---------------CHLHARCVSQEGVARCRCLDGFEGDGFSCT 860
G C P + C HA C + G RC C +G+ GDGF+CT
Sbjct: 1344 GSFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCT 1403
Query: 861 PSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGW--SGDGRVCVAIDECELD---MRGG 915
+ CS + N +C+ + G + C C G+ S DG+ C IDEC L + G
Sbjct: 1404 DLDECS--ENLNLCGNGQCL-NAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGT 1460
Query: 916 CHTDALCSYVGPGQSRCTCKLGFAGD--GYQCSPI----DPCRAGNGGCHGLATCRAVGG 969
CH PG RC C++G+ D G C+ + DP +G C
Sbjct: 1461 CHN-------LPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISGNCVNTP------- 1506
Query: 970 GQRVCTCPPGF 980
G +C CPP F
Sbjct: 1507 GSYICDCPPDF 1517
Score = 92.8 bits (229), Expect = 4e-18
Identities = 83/289 (28%), Positives = 108/289 (37%), Gaps = 33/289 (11%)
Query: 719 GCCKGFFGP-DCTQCPGGFSNP----CYGKGNCS----------DGIQGNGACLCFPDYK 763
G C G C PG S P C CS +G+ C C P
Sbjct: 1169 GRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQP--- 1225
Query: 764 GIACHICSNPNKHGEQCQEDCG-CVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDC 822
G A ++C+++ C G C N PG + C GF ++ D
Sbjct: 1226 GFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGE----YRCLCYDGFMASEDMKTCVDV 1281
Query: 823 GPTGLAQHCHLHARCVSQEGVARCRCLDGFEGDG--FSCTPSNPCSHPDRGGCSENAECV 880
L + L C + +G C C G+ G CT N C C ++A C
Sbjct: 1282 NECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHN-CGKHAVCT 1340
Query: 881 PGSLGTHHCTCHKGWSGDGRVCVAIDECELDMRGGCHTDALCSYVGPGQSRCTCKLGFAG 940
+ G+ C+C GW GDG C +DEC C A C G RC CK G+ G
Sbjct: 1341 -NTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHM-CSQHADCKNT-MGSYRCLCKEGYTG 1397
Query: 941 DGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGF--GGDGFSC 987
DG+ C+ +D C C G C GG R C C GF DG +C
Sbjct: 1398 DGFTCTDLDECSENLNLC-GNGQCLNAPGGYR-CECDMGFVPSADGKAC 1444
Score = 88.2 bits (217), Expect = 9e-17
Identities = 79/260 (30%), Positives = 108/260 (41%), Gaps = 43/260 (16%)
Query: 1945 GCHRNCVTT--TWKPSCCPG-------HYGSECQACPGGPSSPCSDRGVCMDGMSGSGQC 1995
GC C + +++ SC PG ++ C P+ D G C + + G +C
Sbjct: 1207 GCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPN--ICDGGQCTN-IPGEYRC 1263
Query: 1996 LCRSGFAGT----ACELCAPGAFGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCE 2051
LC GF + C P+ + G C E GS C CD G++G + +
Sbjct: 1264 LCYDGFMASEDMKTCVDVNECDLNPNI-----CLSGTC-ENTKGSFICHCDMGYSGKKGK 1317
Query: 2052 V---QLELQPVCTPPCAPEAVCR--AGN-SCECSLGYEGDGRVCTVADLCQDGHGGCSEH 2105
+ + C AVC AG+ C CS G+ GDG CT D C +G CS+H
Sbjct: 1318 TGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQH 1377
Query: 2106 ANCSQVGTMVTCTCLPDYEGDGWSCRARNPCTDGHRGGCSEHANCLSTG--LNT---RRC 2160
A+C C C Y GDG++ CTD CSE+ N G LN RC
Sbjct: 1378 ADCKNTMGSYRCLCKEGYTGDGFT------CTD--LDECSENLNLCGNGQCLNAPGGYRC 1429
Query: 2161 ECHAGYV--GDGLQCLEESE 2178
EC G+V DG C + E
Sbjct: 1430 ECDMGFVPSADGKACEDIDE 1449
Score = 80.5 bits (197), Expect = 2e-14
Identities = 86/298 (28%), Positives = 116/298 (38%), Gaps = 61/298 (20%)
Query: 715 IMEQGCCKGFFGPDCTQCPGGFSNP-----CYGKGNCSDG--IQGNGACL---------C 758
+ E G C G +CP GF C C +G Q N C+ C
Sbjct: 1776 VCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDC 1835
Query: 759 FPDYKGIACHICSNPNKHGEQCQEDCG-CVHGLCDNRPGSGGVCQQGTCAPGFSGR---- 813
P Y+ + C++ N +CQE C HG C + GS C C GF
Sbjct: 1836 KPGYRFTSTGQCNDRN----ECQEIPNICSHGQCIDTVGSF-YC---LCHTGFKTNDDQT 1887
Query: 814 FC---NESMGD-CGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGDGFSCTPSNPCSHPD 869
C NE D CG + C + G CRC GF + +N C D
Sbjct: 1888 MCLDINECERDACG----------NGTCRNTIGSFNCRC-----NHGFILSHNNDCIDVD 1932
Query: 870 R-----GGCSENAECVPGSLGTHHCTCHKGW--SGDGRVCVAIDECELDMRGGCHTDALC 922
G N +C+ ++G+ C C++G+ + DGR CV I+EC L+ R C C
Sbjct: 1933 ECASGNGNLCRNGQCI-NTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPR-KC-APGTC 1989
Query: 923 SYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGF 980
+ G RC C G++ +C ID C C L TC G + C CP GF
Sbjct: 1990 QNL-DGSYRCICPPGYSLQNEKCEDIDECVEEPEIC-ALGTCSNTEGSFK-CLCPEGF 2044
Score = 74.7 bits (182), Expect = 1e-12
Identities = 97/381 (25%), Positives = 140/381 (36%), Gaps = 79/381 (20%)
Query: 656 EEQHKIVAGSCVDCQALNTS---TCPPNSVKLDIFPKECVYIHDPTGL---NVLKKGC-- 707
E + + G C + + LNT TC N P + + + G VL+ C
Sbjct: 2292 ENECQTKPGICENGRCLNTRGSYTCECND-GFTASPNQDECLDNREGYCFTEVLQNMCQI 2350
Query: 708 -ASYCNQTIMEQGCCKGF--FGPDCTQCPG----GFSNPC-YGKGNCSDGI--------- 750
+S N + CC G +GP C CP F C +G+G ++G
Sbjct: 2351 GSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVIH 2410
Query: 751 -----------QGNGACLC----FPDYKGIACHICSNPNKHGEQCQEDCGCVHGLCDNRP 795
+G+ C+C PD G +C + N+ + C + +C N
Sbjct: 2411 DVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPC-------NFICKNTE 2463
Query: 796 GSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGD 855
GS Q +C G+ + S D QH + CV+ G C+C GF
Sbjct: 2464 GS----YQCSCPKGYILQEDGRSCKDLDECATKQH-NCQFLCVNTIGGFTCKCPPGFTQH 2518
Query: 856 GFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGD--GRVCVAIDECELDMR 913
SC +N C+ D C C + G+ C C +G+S D G C +DECE + R
Sbjct: 2519 HTSCIDNNECT-SDINLCGSKGIC-QNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHR 2576
Query: 914 --GGCHTDALCSYVGPGQSRCTCKLGFAG--DGYQCSPIDPCRA----GNGGCHGLATCR 965
GC G RC+C G+ QC + C + G CH
Sbjct: 2577 CQHGCQNII-------GGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCHNTL--- 2626
Query: 966 AVGGGQRVCTCPPGFGGDGFS 986
G C CP GF + FS
Sbjct: 2627 ----GSYKCMCPAGFQYEQFS 2643
Score = 72.0 bits (175), Expect = 7e-12
Identities = 73/297 (24%), Positives = 108/297 (36%), Gaps = 40/297 (13%)
Query: 32 CDVKTTFVTHVPCTSCAAIKKQTCPSGWLRELPDQITQDCRYEVQLGGSMVSMSGCRRKC 91
C++ + C + + C G+ PD++ + V + + GC C
Sbjct: 1159 CELSAHLCPNGRCVNLIGKYQCACNPGY-HSTPDRL-----FCVDIDECSIMNGGCETFC 1212
Query: 92 RKQV--VQKACCPGYW-------GSRCHECPGGAETPCNGHGTCLDGMDRNGTCVCQENF 142
+ +C PG+ + EC G T + G R C+C + F
Sbjct: 1213 TNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYR---CLCYDGF 1269
Query: 143 RGSA-CQECQDPNR--FGPDCQSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQELPVC 199
S + C D N P+ C+ G C + +G C C GY+G
Sbjct: 1270 MASEDMKTCVDVNECDLNPNI-----CLSGTCEN-TKGSFICHCDMGYSGKKGKTGCTDI 1323
Query: 200 QELR-----CPQNTQCSAEAPS--CRCLPGYTQQGSECRAPNPCWPSP--CSLLAQCSVS 250
E C ++ C+ A S C C PG+ G +C + C CS A C +
Sbjct: 1324 NECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCK-N 1382
Query: 251 PKGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPGLV 307
G +C C E Y GDG C D C++NL C + L PG C C G V
Sbjct: 1383 TMGSYRCLCKEGYTGDGFTCTDLDECSENLNLCGNGQCL---NAPGGYRCECDMGFV 1436
Score = 72.0 bits (175), Expect = 7e-12
Identities = 91/373 (24%), Positives = 126/373 (33%), Gaps = 117/373 (31%)
Query: 715 IMEQGCCKGFFGPDCTQCPGGFS-----------NPCYGKGNCSDGI----QGNGACLCF 759
+ + G C FG +CP G+ N C G C G GN C+C
Sbjct: 1616 LCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICP 1675
Query: 760 PDYK----GIAC-----------HICSNPNKHGE----QCQEDCGCVHG----------- 789
PDY G C + N GE ++ C C +
Sbjct: 1676 PDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQ 1735
Query: 790 -----------LC-DNRPG------------------SGGVCQQGTCAPGFS-------- 811
LC RPG GVC+ G C
Sbjct: 1736 CPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCENGVCINMVGSFRCECPV 1795
Query: 812 GRFCNESMGDCGPTGLAQH---CHLHARCVSQEGVARCRCLDGFEGDGFSCTPSNPCSHP 868
G F N+ + C Q+ C +A C++ G RC C G+ T + C+
Sbjct: 1796 GFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDCKPGYR-----FTSTGQCN-- 1848
Query: 869 DRGGCSE------NAECVPGSLGTHHCTCHKGW--SGDGRVCVAIDECELDM--RGGCHT 918
DR C E + +C+ ++G+ +C CH G+ + D +C+ I+ECE D G C
Sbjct: 1849 DRNECQEIPNICSHGQCI-DTVGSFYCLCHTGFKTNDDQTMCLDINECERDACGNGTCRN 1907
Query: 919 DALCSYVGPGQSRCTCKLGF-AGDGYQCSPIDPCRAGNGG-CHGLATCRAVGGGQRVCTC 976
G C C GF C +D C +GNG C VG Q C C
Sbjct: 1908 TI-------GSFNCRCNHGFILSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQ--CQC 1958
Query: 977 PPGF--GGDGFSC 987
G+ DG +C
Sbjct: 1959 NEGYEVAPDGRTC 1971
Score = 71.2 bits (173), Expect = 1e-11
Identities = 72/268 (26%), Positives = 101/268 (37%), Gaps = 56/268 (20%)
Query: 1956 KPSCCPG----HYGSECQACPGGPSSP------------------------CSDRGVCMD 1987
K CC +G C+ CP P C + VC
Sbjct: 2080 KQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKH 2139
Query: 1988 GM----SGSGQCLCRSGF--AGTACELCAPGAFGPHCQACRCTVHGRCDEGLGGSGSCFC 2041
G GS +C C G+ AG C + G C +G C +GG C C
Sbjct: 2140 GQCINTDGSYRCECPFGYILAGNECVDTDECSVGNPCG------NGTCKNVIGGF-ECTC 2192
Query: 2042 DEGWT-GPRCEVQLELQPVCTPP--CAPEAVCRAGN-SCECSLGY--EGDGRVCTVADLC 2095
+EG+ GP + ++ P CA V G+ C+C +GY D R+C D C
Sbjct: 2193 EEGFEPGPMMTCE-DINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDEC 2251
Query: 2096 QDGHGGCSE-HANCSQVGTMVTCTCLPDYE--GDGWSCRARNPCTDGHRGGCSEHANCLS 2152
++G C+E C + C C P Y+ DG C N C + G E+ CL+
Sbjct: 2252 EEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQT--KPGICENGRCLN 2309
Query: 2153 TGLNTRRCECHAGYVGDGLQ--CLEESE 2178
T + CEC+ G+ Q CL+ E
Sbjct: 2310 T-RGSYTCECNDGFTASPNQDECLDNRE 2336
Score = 69.3 bits (168), Expect = 5e-11
Identities = 86/358 (24%), Positives = 124/358 (34%), Gaps = 69/358 (19%)
Query: 654 CSEEQHKIVAGSCVDCQALNTSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKGCASYCNQ 713
C E K G+C + CPP + ++C I + C
Sbjct: 1977 CLLEPRKCAPGTCQNLDGSYRCICPPG---YSLQNEKCEDIDE----------CVE--EP 2021
Query: 714 TIMEQGCCKGFFGPDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNP 773
I G C G CP GFS G+ C D C+ ++G C S+P
Sbjct: 2022 EICALGTCSNTEGSFKCLCPEGFSLSSSGR-RCQDLRMS----YCYAKFEGGKC---SSP 2073
Query: 774 NKHGEQCQEDCGCVHG--------LCDNRPGSG--GVCQQGT---CAPGFSGRFCNESMG 820
QE C + G LC P +C G+ P S M
Sbjct: 2074 KSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSA----VDMD 2129
Query: 821 DCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGDGFSCTPSNPCS--HPDRGGCSENAE 878
+C + +H +C++ +G RC C G+ G C ++ CS +P G +N
Sbjct: 2130 ECKEPDVCKH----GQCINTDGSYRCECPFGYILAGNECVDTDECSVGNPCGNGTCKNV- 2184
Query: 879 CVPGSLGTHHCTCHKGWS-GDGRVCVAIDECELDMRGGCHTDALCSY---VGPGQSRCTC 934
+G CTC +G+ G C I+EC LC++ G C C
Sbjct: 2185 -----IGGFECTCEEGFEPGPMMTCEDINEC-------AQNPLLCAFRCVNTYGSYECKC 2232
Query: 935 KLGFA--GDGYQCSPIDPCRAGNGGC-HGLATCRAVGGGQRVCTCPPGF--GGDGFSC 987
+G+ D C D C G C C+ + G +C C PG+ DG C
Sbjct: 2233 PVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNL-IGTYMCICGPGYQRRPDGEGC 2289
Score = 68.6 bits (166), Expect = 8e-11
Identities = 89/388 (22%), Positives = 140/388 (36%), Gaps = 82/388 (21%)
Query: 643 PPTILPI-LPKHCSEEQHKIVAGSCVDCQALNTSTCPPNSVKLDIFPKECVYIHDPTGLN 701
PP +LP+ + +C ++ G C+ C +LD+ EC+ + +
Sbjct: 441 PPRVLPVNVTDYCQLVRYLCQNGRCIPTPGSCRCECN-KGFQLDL-RGECIDVDE----- 493
Query: 702 VLKKGCASYCNQTIMEQGCCKGFFGPDCTQCPGGFSNP-----CYGKGNCSDG--IQGNG 754
C + G C G QC G+ + C C I NG
Sbjct: 494 ---------CEKNPCAGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNG 544
Query: 755 ACLCFPDYKGIACHICSNPNKHGEQCQE--DCG----CVHGLCDNRPGSGGVCQQGTCAP 808
C+ C+ + + G+ C++ +C C++G+C N GS + C P
Sbjct: 545 RCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSF----KCICKP 600
Query: 809 GFS----GRFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEG--DGFSCTPS 862
GF GR+C + + +C G+ ++ RCV+ +G RC C G DG C +
Sbjct: 601 GFQLASDGRYCKD-INECETPGIC----MNGRCVNTDGSYRCECFPGLAVGLDGRVCVDT 655
Query: 863 NPCSHPDRGGCSENAECVP---GSLGTHHCTCHKGWSGDGRVCVA--------------- 904
+ S G + +C+ G++ C C G C
Sbjct: 656 HMRS--TCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSS 713
Query: 905 ----------IDECELDMRGGCHTDALCSYVGPGQSRCTCKLGFAGD--GYQCSPIDPCR 952
I+EC LD + +C + G +C C G+ D G C I+ C
Sbjct: 714 GPGMTSAGSDINECALD--PDICPNGICENL-RGTYKCICNSGYEVDSTGKNCVDINECV 770
Query: 953 AGNGGCHGLATCRAVGGGQRVCTCPPGF 980
+ C CR G VCTCP GF
Sbjct: 771 LNSLLCDN-GQCRNT-PGSFVCTCPKGF 796
Score = 68.2 bits (165), Expect = 1e-10
Identities = 79/321 (24%), Positives = 109/321 (33%), Gaps = 73/321 (22%)
Query: 721 CKGFFGPDCTQCPGGF-----SNPCYGKGNCSDG-------------IQGNGACLCFPDY 762
C +G +CP G+ C + C +G + G C+C P Y
Sbjct: 2221 CVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGY 2280
Query: 763 KGIACHICSNPNKHG----EQCQEDCG-CVHGLCDNRPGSGGV-CQQGTCAPGFSGRFCN 816
+ P+ G +CQ G C +G C N GS C G A +
Sbjct: 2281 Q-------RRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLD 2333
Query: 817 ESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGDGFSCTP---------SNPCSH 867
G C L C + + + + C C DG G G C C H
Sbjct: 2334 NREGYCFTEVLQNMCQIGSSNRNPVTKSEC-CCDGGRGWGPHCEICPFQGTVAFKKLCPH 2392
Query: 868 --------PDRGGCS------ENAECVPGSLGTHHCTCHKGWSGD--GRVCVAIDECELD 911
D C N ECV G++HC C G++ D G CV ++EC
Sbjct: 2393 GRGFMTNGADIDECKVIHDVCRNGECV-NDRGSYHCICKTGYTPDITGTSCVDLNECN-- 2449
Query: 912 MRGGCHTDALCSYV---GPGQSRCTCKLGFA--GDGYQCSPIDPCRAGNGGCHGLATCRA 966
C+++ G +C+C G+ DG C +D C C L
Sbjct: 2450 -----QAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCV-NT 2503
Query: 967 VGGGQRVCTCPPGFGGDGFSC 987
+GG C CPPGF SC
Sbjct: 2504 IGGF--TCKCPPGFTQHHTSC 2522
Score = 67.8 bits (164), Expect = 1e-10
Identities = 83/331 (25%), Positives = 119/331 (35%), Gaps = 74/331 (22%)
Query: 1272 CVNCTRRFRCT--QGFQLQDTPRKSCVYRSGFSFSR----GCSYTCAKKIQVPDCCPGFF 1325
C N F+C +GF L + R+ R + +++ CS ++ +CC
Sbjct: 2029 CSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALK 2088
Query: 1326 GT-------LC--EP-------CPGGLG------------------GVCSGHGQCQDRFL 1351
G LC EP CP G G VC HGQC +
Sbjct: 2089 GEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCK-HGQCINTD- 2146
Query: 1352 GSGECHCHEGF--HGTAC---EVCELGRYGPNCTGVCDCAHGLCQEGLQGDGSCVCNVGW 1406
GS C C G+ G C + C +G C +G C+ + G C C G+
Sbjct: 2147 GSYRCECPFGYILAGNECVDTDECSVGN---------PCGNGTCKNVI-GGFECTCEEGF 2196
Query: 1407 QG---LRCDQKITSPQCPRKCDPNANCVQDSAGASTCACAAGY--SGNGIFCSEVDPCAH 1461
+ + C+ Q P C CV ++ G+ C C GY + C + D C
Sbjct: 2197 EPGPMMTCEDINECAQNPLLCA--FRCV-NTYGSYECKCPVGYVLREDRRMCKDEDECEE 2253
Query: 1462 GHGGCSPHANCTKVAPGQRTCTCQDGYM--GDGELCQEINSCLIHHGGCHIHAECIPTGP 1519
G C+ K G C C GY DGE C + N C G C + C+ T
Sbjct: 2254 GKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICE-NGRCLNT-R 2311
Query: 1520 QQVSCSCREGYSGDGIRTCELLDPCSKNNGG 1550
+C C +G++ + D C N G
Sbjct: 2312 GSYTCECNDGFTASPNQ-----DECLDNREG 2337
Score = 67.0 bits (162), Expect = 2e-10
Identities = 59/215 (27%), Positives = 86/215 (40%), Gaps = 21/215 (9%)
Query: 1378 NCTGVCDCAHGLCQEG----LQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQD 1433
N T C LCQ G G C CN G+Q + I +C + C+ +
Sbjct: 448 NVTDYCQLVRYLCQNGRCIPTPGSCRCECNKGFQLDLRGECIDVDECEKNPCAGGECINN 507
Query: 1434 SAGASTCACAAGYSG--NGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGY--M 1489
G+ TC C AGY C ++D C C+ + C G C C G+
Sbjct: 508 Q-GSYTCQCRAGYQSTLTRTECRDIDECLQNGRICN-NGRCIN-TDGSFHCVCNAGFHVT 564
Query: 1490 GDGELCQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGY--SGDGIRTCELLDPCSKN 1547
DG+ C++++ C I + ++ CI C C+ G+ + DG R C+ ++ C
Sbjct: 565 RDGKNCEDMDECSIRN--MCLNGMCI-NEDGSFKCICKPGFQLASDG-RYCKDINEC--E 618
Query: 1548 NGGCSPYATCKSTGDGQRTCTCDTAHTVG-DGLTC 1581
G C +T DG C C VG DG C
Sbjct: 619 TPGICMNGRCVNT-DGSYRCECFPGLAVGLDGRVC 652
Score = 66.2 bits (160), Expect = 4e-10
Identities = 70/259 (27%), Positives = 92/259 (35%), Gaps = 63/259 (24%)
Query: 1945 GCHRNCVTT--TWKPSCCPGHYG-----SECQACPGGPSSPCSDRGVCMDGMSGSGQCLC 1997
G H C T ++K SC PG G ++ C G + CS C + M GS +CLC
Sbjct: 1334 GKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNG-THMCSQHADCKNTM-GSYRCLC 1391
Query: 1998 RSGFAGTACELCAPGAFGPHCQACRCTVHGRCDEGLG--GSGSCFCDEGWTGPRCEVQLE 2055
+ G+ G CT C E L G+G C G G RCE +
Sbjct: 1392 KEGYTG---------------DGFTCTDLDECSENLNLCGNGQCLNAPG--GYRCECDMG 1434
Query: 2056 LQPVCT-------PPCAPEAVCRAGNS--------CECSLGYEGD--GRVCTVADLCQDG 2098
P C+ +C G CEC +GYE D G CT + C D
Sbjct: 1435 FVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDP 1494
Query: 2099 HGGCSEHANCSQVGTMVTCTCLPDYEGDGWSCRARNPCTDGHRGGC------------SE 2146
S NC C C PD+E + R C D G C +
Sbjct: 1495 TTCIS--GNCVNTPGSYICDCPPDFELN----PTRVGCVDTRSGNCYLDIRPRGDNGDTA 1548
Query: 2147 HANCLSTGLNTRRCECHAG 2165
+N + G++ C C G
Sbjct: 1549 CSNEIGVGVSKASCCCSLG 1567
Score = 65.5 bits (158), Expect = 7e-10
Identities = 86/339 (25%), Positives = 118/339 (34%), Gaps = 80/339 (23%)
Query: 1255 VGSSRCLHSHAEALREKCVNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKK 1314
VGS RC +K + C C G Q C+ +G SY C
Sbjct: 1786 VGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAE--CINTAG-------SYRC--- 1833
Query: 1315 IQVPDCCPGFFGTLCEPCPGG-----LGGVCSGHGQCQDRFLGSGECHCHEGFHG----T 1365
DC PG+ T C + +CS HGQC D +GS C CH GF T
Sbjct: 1834 ----DCKPGYRFTSTGQCNDRNECQEIPNICS-HGQCIDT-VGSFYCLCHTGFKTNDDQT 1887
Query: 1366 AC--------EVCELGR-------------------YGPNCTGVCDCAHG---LCQEG-- 1393
C + C G + +C V +CA G LC+ G
Sbjct: 1888 MCLDINECERDACGNGTCRNTIGSFNCRCNHGFILSHNNDCIDVDECASGNGNLCRNGQC 1947
Query: 1394 --LQGDGSCVCNVGWQ----GLRCDQKITSPQC---PRKCDPNANCVQDSAGASTCACAA 1444
G C CN G++ G C + +C PRKC P Q+ G+ C C
Sbjct: 1948 INTVGSFQCQCNEGYEVAPDGRTC---VDINECLLEPRKCAPGT--CQNLDGSYRCICPP 2002
Query: 1445 GYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGY--MGDGELCQEINSCL 1502
GYS C ++D C C+ C+ G C C +G+ G CQ++
Sbjct: 2003 GYSLQNEKCEDIDECVEEPEICA-LGTCSN-TEGSFKCLCPEGFSLSSSGRRCQDLRMSY 2060
Query: 1503 IH---HGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTC 1538
+ GG + Q+ C+ + GD C
Sbjct: 2061 CYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELC 2099
Score = 62.0 bits (149), Expect = 7e-09
Identities = 77/323 (23%), Positives = 113/323 (34%), Gaps = 72/323 (22%)
Query: 715 IMEQGCCKGFFGPDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPN 774
+ + G C G QCP G + G+ ++ CF Y+ C +
Sbjct: 920 VCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLE-----TCFLRYEDEECTLPIAGR 974
Query: 775 KHGEQCQEDCGCVHGL--CD-----NRPGSGGVCQQGTCAPGFSGRFCNES---MGDCGP 824
+ C G G C+ N P +C +G PGF+ + D
Sbjct: 975 HRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRG---PGFATKEITNGKPFFKDINE 1031
Query: 825 TGLAQHCHLHARCVSQEGVARCRCLDGF--EGDGFSCTPSNPCS-HPDRGGCSENAECVP 881
+ H +C + G +CRC GF + + +CT + C PD G +CV
Sbjct: 1032 CKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCG---RGQCV- 1087
Query: 882 GSLGTHHCTCHKGWSGDGRV---CVAIDECELD---MRGG-CHTD--------------- 919
+ G C C +G+ + C+ IDEC+ D RGG CH
Sbjct: 1088 NTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLS 1147
Query: 920 ------------ALCSYVGP--------GQSRCTCKLGF--AGDGYQCSPIDPCRAGNGG 957
L +++ P G+ +C C G+ D C ID C NGG
Sbjct: 1148 PNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGG 1207
Query: 958 CHGLATCRAVGGGQRVCTCPPGF 980
C T G C+C PGF
Sbjct: 1208 CETFCT---NSEGSYECSCQPGF 1227
Score = 61.6 bits (148), Expect = 1e-08
Identities = 71/273 (26%), Positives = 100/273 (36%), Gaps = 52/273 (19%)
Query: 1957 PSCCPGHYGSECQACPGGPSSPCSDRGV-------CMDGM-SGSGQCLCRSGFAGTACEL 2008
P+ C Y + C CPG + P ++ + C DG S C C SG +C
Sbjct: 56 PNVCGSRYNAYC--CPGWKTLPGGNQCIVPICRHSCGDGFCSRPNMCTCPSGQIAPSCGS 113
Query: 2009 CAPGAFGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEA 2068
+ HC RC G C + C C +G+ G C QPVC C
Sbjct: 114 RSI----QHCNI-RCMNGGSCSDD-----HCLCQKGYIGTHCG-----QPVCESGCLNGG 158
Query: 2069 VCRAGNSCECSLGYEG--------DGRVCTVA--DLCQDGHGG--CSEHANCSQVG---- 2112
C A N C C+ G+ G G TV +CQ G C++ C+ VG
Sbjct: 159 RCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWG 218
Query: 2113 -TMVTCTCLPDYEGDGWSCRAR-NPCTDGHR----GGCSEHANCLSTGLNTRRCECHAGY 2166
C P G+ R C D G + NC++T + + C+C AG+
Sbjct: 219 HPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINT-VGSFECKCPAGH 277
Query: 2167 VGDGLQCLEESEPPVDRCLGQPPPCHSDAMCTD 2199
L + + +D C P C CT+
Sbjct: 278 ---KLNEVSQKCEDIDECSTIPGICEG-GECTN 306
Score = 61.6 bits (148), Expect = 1e-08
Identities = 97/389 (24%), Positives = 129/389 (33%), Gaps = 79/389 (20%)
Query: 16 CLAGFSFVRGQVL--FKGCDVKTTFVTHVPCTSCAAIKKQTCPSGWLRELPDQITQDCRY 73
C G+S ++G C+V + C + K CPSG + +I D R
Sbjct: 896 CGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRL 955
Query: 74 EVQLGGSMVSMSGCRRKCRKQVVQKACC---PGYWGS-RCHECPGGAETP---------- 119
E C + ACC WG+ C ECP TP
Sbjct: 956 ETCF--LRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECP-MRNTPEYEELCPRGP 1012
Query: 120 -------CNGH-------------GTCLDGMDRNG----TCVCQENFR-GSACQECQDPN 154
NG C G RN C C F S + C D +
Sbjct: 1013 GFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDID 1072
Query: 155 --RFGPDCQSVCSCVHGVCNHGPRGDGSCLCFAGYTG-----------PHCDQELPVCQE 201
R PD C G C + P GD C C GY C ++ +C+
Sbjct: 1073 ECRISPDL-----CGRGQCVNTP-GDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRG 1126
Query: 202 LRCPQNTQCSAEAPSCRCLPGY--TQQGSECRAPNPCWPSPCSLLAQCSVSPKGQAQCHC 259
C NT+ S C C PG+ + S C N C S V+ G+ QC C
Sbjct: 1127 GVC-HNTEGSYR---CECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCAC 1182
Query: 260 PENYHG--DGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPGLVSINSNASAGC 317
YH D + C+ D C+ GGC T C G C+C+PG + S
Sbjct: 1183 NPGYHSTPDRLFCVDIDECSIMNGGC---ETFCT-NSEGSYECSCQPGFALMPDQRSCTD 1238
Query: 318 FAFC--SPFSCDRSATCQVTADGKTSCVC 344
C +P CD + G+ C+C
Sbjct: 1239 IDECEDNPNICDGGQCTNI--PGEYRCLC 1265
Score = 61.6 bits (148), Expect = 1e-08
Identities = 57/204 (27%), Positives = 80/204 (39%), Gaps = 16/204 (7%)
Query: 1385 CAHGLCQEGLQGDGSCVCNVGW---QGLRCDQKITSPQCPRKCDPNANCVQDSAGASTCA 1441
C +G+C + G C C VG+ L + I Q C NA C+ ++AG+ C
Sbjct: 1777 CENGVCIN-MVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECI-NTAGSYRCD 1834
Query: 1442 CAAGYSGNGIF-CSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYM--GDGELCQEI 1498
C GY C++ + C CS H C G C C G+ D +C +I
Sbjct: 1835 CKPGYRFTSTGQCNDRNECQEIPNICS-HGQCIDTV-GSFYCLCHTGFKTNDDQTMCLDI 1892
Query: 1499 NSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCK 1558
N C C + C T +C C G+ C +D C+ NG C
Sbjct: 1893 NEC--ERDACG-NGTCRNT-IGSFNCRCNHGFILSHNNDCIDVDECASGNGNLCRNGQCI 1948
Query: 1559 STGDGQRTCTCDTAHTVG-DGLTC 1581
+T G C C+ + V DG TC
Sbjct: 1949 NT-VGSFQCQCNEGYEVAPDGRTC 1971
Score = 60.8 bits (146), Expect = 2e-08
Identities = 86/315 (27%), Positives = 103/315 (32%), Gaps = 80/315 (25%)
Query: 1933 PSLWGRPQGLGRGCHRNCVTTTWKPSCCP--------GHYGSECQACPGGPSSPCSDRGV 1984
P RP G G C T KP C G Y EC G +SP D
Sbjct: 2278 PGYQRRPDGEGCVDENECQT---KPGICENGRCLNTRGSYTCECN--DGFTASPNQDE-- 2330
Query: 1985 CMDGMSGSG-----QCLCRSGFAG----TACELCAPGA--FGPHCQAC---------RCT 2024
C+D G Q +C+ G + T E C G +GPHC+ C +
Sbjct: 2331 CLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLC 2390
Query: 2025 VHGR------------------CDEGL----GGSGSCFCDEGWT----GPRCEVQLELQP 2058
HGR C G GS C C G+T G C V L
Sbjct: 2391 PHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSC-VDLNECN 2449
Query: 2059 VCTPPCAPEAVCR---AGNSCECSLGY--EGDGRVCTVADLCQDGHGGCSEHANCSQVGT 2113
PC +C+ C C GY + DGR C D C C C
Sbjct: 2450 QAPKPC--NFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQ--FLCVNTIG 2505
Query: 2114 MVTCTCLPDYEGDGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGD--GL 2171
TC C P + SC N CT C C +T + CEC G+ D G
Sbjct: 2506 GFTCKCPPGFTQHHTSCIDNNECT-SDINLCGSKGICQNTP-GSFTCECQRGFSLDQTGS 2563
Query: 2172 QCLEESEPPVDRCLG 2186
C + VD C G
Sbjct: 2564 SCED-----VDECEG 2573
Score = 60.1 bits (144), Expect = 3e-08
Identities = 64/243 (26%), Positives = 95/243 (39%), Gaps = 49/243 (20%)
Query: 1318 PDC--CPGFFGTLC--EPCPGGLGGVCSG--------------HGQC-QDRFLGSGECHC 1358
P C CP F GT+ + CP G G + +G +G+C DR GS C C
Sbjct: 2373 PHCEICP-FQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNGECVNDR--GSYHCIC 2429
Query: 1359 HEGFH----GTAC-EVCELGRYGPNCTGVCDCAHGLCQEGLQGDGSCVCNVGW----QGL 1409
G+ GT+C ++ E + C +C + +G C C G+ G
Sbjct: 2430 KTGYTPDITGTSCVDLNECNQAPKPCNFIC--------KNTEGSYQCSCPKGYILQEDGR 2481
Query: 1410 RCDQKITSPQCPRKCDPNANCVQDSAGASTCACAAGYSGNGIFCSEVDPCAHGHGGCSPH 1469
C +C K ++ G TC C G++ + C + + C C
Sbjct: 2482 SCKDL---DECATKQHNCQFLCVNTIGGFTCKCPPGFTQHHTSCIDNNECTSDINLCGSK 2538
Query: 1470 ANCTKVAPGQRTCTCQDGYMGD--GELCQEINSCLIHHGGCHIHAECIPTGPQQVSCSCR 1527
C PG TC CQ G+ D G C++++ C +H C + I G CSC
Sbjct: 2539 GICQNT-PGSFTCECQRGFSLDQTGSSCEDVDECEGNH-RCQHGCQNIIGG---YRCSCP 2593
Query: 1528 EGY 1530
+GY
Sbjct: 2594 QGY 2596
Score = 58.9 bits (141), Expect = 6e-08
Identities = 54/183 (29%), Positives = 71/183 (38%), Gaps = 36/183 (19%)
Query: 824 PTGLAQHCHL------HARCVSQEGVARCRCLDGFEGD-GFSCTPSNPC-SHPDRGGCSE 875
P + +C L + RC+ G RC C GF+ D C + C +P GG
Sbjct: 446 PVNVTDYCQLVRYLCQNGRCIPTPGSCRCECNKGFQLDLRGECIDVDECEKNPCAGG--- 502
Query: 876 NAECVPGSLGTHHCTCHKGWSG--DGRVCVAIDECELDMR----GGC-HTDALCSYVGPG 928
EC+ + G++ C C G+ C IDEC + R G C +TD G
Sbjct: 503 --ECI-NNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTD--------G 551
Query: 929 QSRCTCKLGF--AGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGF--GGDG 984
C C GF DG C +D C N +G+ G C C PGF DG
Sbjct: 552 SFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINE---DGSFKCICKPGFQLASDG 608
Query: 985 FSC 987
C
Sbjct: 609 RYC 611
Score = 58.9 bits (141), Expect = 6e-08
Identities = 87/345 (25%), Positives = 125/345 (36%), Gaps = 78/345 (22%)
Query: 1278 RFRCTQGFQLQ---------DTPRKSCVYRSGFSFSRGCSYTCAKKIQVPDCCPGFFGTL 1328
R C +GFQL + + C G + SYTC C G+ TL
Sbjct: 473 RCECNKGFQLDLRGECIDVDECEKNPCA--GGECINNQGSYTC-------QCRAGYQSTL 523
Query: 1329 ----CEPCPGGL--GGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCTGV 1382
C L G +C+ +G+C + GS C C+ GFH T R G NC +
Sbjct: 524 TRTECRDIDECLQNGRICN-NGRCINTD-GSFHCVCNAGFHVT--------RDGKNCEDM 573
Query: 1383 CDCA-HGLCQEGL----QGDGSCVCNVGWQ----GLRCDQKITSPQCPRKCDPNANCVQD 1433
+C+ +C G+ G C+C G+Q G C + I + P C N CV +
Sbjct: 574 DECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYC-KDINECETPGIC-MNGRCV-N 630
Query: 1434 SAGASTCACAAGYSG--NGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRT---CTCQDGY 1488
+ G+ C C G + +G C + + +GG C K G T C C
Sbjct: 631 TDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYK-RGQCIKPLFGAVTKSECCCASTE 689
Query: 1489 MGDGELCQE------------------INSCLIHHGGCHIHAECIPTGPQQ-----VSCS 1525
GE CQ + S C + + P G + C
Sbjct: 690 YAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICENLRGTYKCI 749
Query: 1526 CREGYSGDGI-RTCELLDPCSKNNGGCSPYATCKSTGDGQRTCTC 1569
C GY D + C ++ C N+ C C++T G CTC
Sbjct: 750 CNSGYEVDSTGKNCVDINECVLNSLLCD-NGQCRNT-PGSFVCTC 792
Score = 58.5 bits (140), Expect = 8e-08
Identities = 45/154 (29%), Positives = 61/154 (39%), Gaps = 16/154 (10%)
Query: 164 CSCVHGVCNHGP----RGDGSCLCFAGYT----GPHCDQELPVCQELRCPQNTQCSAEAP 215
C +H VC +G RG C+C GYT G C +L C + P N C
Sbjct: 2406 CKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSC-VDLNECNQAPKPCNFICKNTEG 2464
Query: 216 S--CRCLPGYTQQ--GSECRAPNPCWPSPCSLLAQCSVSPKGQAQCHCPENYHGDGMVCL 271
S C C GY Q G C+ + C + C V+ G C CP + C+
Sbjct: 2465 SYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLC-VNTIGGFTCKCPPGFTQHHTSCI 2523
Query: 272 PKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPG 305
+ CT ++ C S +C PG C C+ G
Sbjct: 2524 DNNECTSDINLCGSKG-IC-QNTPGSFTCECQRG 2555
Score = 57.8 bits (138), Expect = 1e-07
Identities = 90/395 (22%), Positives = 129/395 (32%), Gaps = 78/395 (19%)
Query: 25 GQVLFKG---CDVKTTFVTHVPCTSCAAIKKQTCPSGWLRELPDQITQD---CRYEVQLG 78
G+ FK C + + TH C + K C SG+ + ++ D CR L
Sbjct: 1022 GKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLC 1081
Query: 79 G---------------------SMVSMSGCRR--KCRKQ--VVQKACCPGYWGSRCHECP 113
G + M C +C++ + + C GS ECP
Sbjct: 1082 GRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECP 1141
Query: 114 GGAETPCNGHGTCLD--------GMDRNGTCVCQENFRGSACQECQDPNRFGPD---CQS 162
G + N C+D + NG CV N G C PD C
Sbjct: 1142 PGHQLSPN-ISACIDINECELSAHLCPNGRCV---NLIGKYQCACNPGYHSTPDRLFCVD 1197
Query: 163 V--CSCVHGVCNH---GPRGDGSCLCFAGYTG----------PHCDQELPVCQELRCPQN 207
+ CS ++G C G C C G+ C+ +C +C
Sbjct: 1198 IDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQC--- 1254
Query: 208 TQCSAEAPSCRCLPGY--TQQGSECRAPNPCWPSPCSLLAQCSVSPKGQAQCHCPENYHG 265
T E C C G+ ++ C N C +P L+ + KG CHC Y G
Sbjct: 1255 TNIPGEY-RCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSG 1313
Query: 266 DGMVCLPKDPCTDNLGGCPSNSTLC-----VYQKPGQAFCTCRPGLVSINSNASAGCFAF 320
K CTD + C + C G C+C PG + +
Sbjct: 1314 KK----GKTGCTD-INECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECS 1368
Query: 321 CSPFSCDRSATCQVTADGKTSCVCRESEVGDGRAC 355
C + A C+ T G C+C+E GDG C
Sbjct: 1369 NGTHMCSQHADCKNTM-GSYRCLCKEGYTGDGFTC 1402
Score = 56.2 bits (134), Expect = 4e-07
Identities = 93/380 (24%), Positives = 128/380 (33%), Gaps = 91/380 (23%)
Query: 1275 CTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRGCSYTC-AKKIQVPDCC--------PGFF 1325
C+ R C G + + C+ + GF + Y + + P C G +
Sbjct: 576 CSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNGRCVNTDGSY 635
Query: 1326 GTLCEPCPG---GLGG----------VCSG---HGQCQDRFLGS---GECHCH--EGFHG 1364
CE PG GL G C G GQC G+ EC C E G
Sbjct: 636 R--CECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFG 693
Query: 1365 TACEVCE---------LGRYGPNCTGVCD-----------CAHGLCQEGLQGDGSCVCNV 1404
C+ C L GP T C +G+C E L+G C+CN
Sbjct: 694 EPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGIC-ENLRGTYKCICNS 752
Query: 1405 GWQ----GLRCDQKITSPQCPRKCDPNANCVQDSAGASTCACAAG--YSGNGIFCSEVDP 1458
G++ G C CD N C +++ G+ C C G Y + C ++D
Sbjct: 753 GYEVDSTGKNCVDINECVLNSLLCD-NGQC-RNTPGSFVCTCPKGFIYKPDLKTCEDIDE 810
Query: 1459 CAHGHGGCSPHAN-CTKVAPGQRTCTCQDGYMGDGE--LCQEI-----------NSCLIH 1504
C SP N K +PG C C D +C E C I+
Sbjct: 811 CES-----SPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEIN 865
Query: 1505 HGGCHIHAECI---------PTGPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYA 1555
G + ++C P QV C +GYS CE +D C G C
Sbjct: 866 INGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCK-NG 924
Query: 1556 TCKSTGDGQRTCTCDTAHTV 1575
C +T G C C + T+
Sbjct: 925 LCVNT-RGSFKCQCPSGMTL 943
Score = 55.1 bits (131), Expect = 9e-07
Identities = 80/320 (25%), Positives = 118/320 (36%), Gaps = 74/320 (23%)
Query: 654 CSEEQHKIVAGSCVDCQALNTSTCPPNSVKLDIFPKECV----YIHDPTGLNVLKKGCAS 709
CS AGS ++ AL+ CP + +C+ Y D TG N +
Sbjct: 711 CSSGPGMTSAGSDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDIN-EC 769
Query: 710 YCNQTIMEQGCCKGFFGPDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHI 769
N + + G C+ G CP GF + PD K
Sbjct: 770 VLNSLLCDNGQCRNTPGSFVCTCPKGF--------------------IYKPDLK-----T 804
Query: 770 CSNPNKHGEQCQEDCGCVHGLCDNRPGSGGVCQ---QGTCAPGFSGRFCNESM-GDCGPT 825
C + ++C E C++G+C N PGS +C+ + T P + C E++ G C T
Sbjct: 805 CEDI----DEC-ESSPCINGVCKNSPGS-FICECSSESTLDP--TKTICIETIKGTCWQT 856
Query: 826 GLAQHCH-------LHARCVSQEGVA------RCRCLDGFEGDGFSCTPSNPCSHPDR-- 870
+ C L ++C S G A C+ +D G G+S C D
Sbjct: 857 VIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQ-VDPICGKGYSRIKGTQCEDIDECE 915
Query: 871 --GGCSENAECVPGSLGTHHCTCHKGWSGD--GRVCVAI-----------DECELDMRGG 915
G +N CV + G+ C C G + D GR+C+ I +EC L + G
Sbjct: 916 VFPGVCKNGLCV-NTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAGR 974
Query: 916 CHTDALCSYVGPGQSRCTCK 935
DA C VG C+
Sbjct: 975 HRMDACCCSVGAAWGTEECE 994
Score = 54.3 bits (129), Expect = 2e-06
Identities = 74/298 (24%), Positives = 103/298 (34%), Gaps = 59/298 (19%)
Query: 1318 PDCCPGFFGTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGF--HGTACEVCELGRY 1375
P+ C + C CPG G QC + C +GF C C G+
Sbjct: 56 PNVCGSRYNAYC--CPGWK--TLPGGNQC---IVPICRHSCGDGFCSRPNMC-TCPSGQI 107
Query: 1376 GPNC--TGVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQD 1433
P+C + C G D C+C G+ G C Q P C C CV
Sbjct: 108 APSCGSRSIQHCNIRCMNGGSCSDDHCLCQKGYIGTHCGQ----PVCESGCLNGGRCV-- 161
Query: 1434 SAGASTCACAAGYSG-------------------------NGIFCSEVDPCAH-GHGGCS 1467
+ CAC G++G +GI C++ CA G
Sbjct: 162 --APNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGH 219
Query: 1468 PHANCTKVAPGQRTCTCQDGYMGD--GELCQEINSCLIHHGGCHIHAECIPTGPQQVSCS 1525
P C P Q C+ G++ + CQ+++ C G C CI T C
Sbjct: 220 PCEMC----PAQ-PHPCRRGFIPNIRTGACQDVDECQAIPGLCQ-GGNCINT-VGSFECK 272
Query: 1526 CREGYSGDGI-RTCELLDPCSKNNGGCSPYATCKSTGDGQRTCTCDTA-HTVGDGLTC 1581
C G+ + + + CE +D CS G C C +T C C +T DG C
Sbjct: 273 CPAGHKLNEVSQKCEDIDECSTIPGICEG-GECTNTVSSY-FCKCPPGFYTSPDGTRC 328
Score = 53.1 bits (126), Expect = 3e-06
Identities = 55/215 (25%), Positives = 73/215 (33%), Gaps = 35/215 (16%)
Query: 98 KACCPGY--WGSRCHECPGGAETPC-----NGHGTCLDGMD-----------RNGTCVCQ 139
+ CC G WG C CP +G G +G D RNG CV
Sbjct: 2362 ECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNGECVND 2421
Query: 140 ENFRGSACQECQDPNRFGPDCQSVCSCVHGV--CNH---GPRGDGSCLCFAGYT----GP 190
C+ P+ G C + C CN G C C GY G
Sbjct: 2422 RGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGR 2481
Query: 191 HCDQELPVC--QELRCPQNTQCSAEAPSCRCLPGYTQQGSECRAPNPCWP--SPCSLLAQ 246
C ++L C ++ C + +C+C PG+TQ + C N C + C
Sbjct: 2482 SC-KDLDECATKQHNCQFLCVNTIGGFTCKCPPGFTQHHTSCIDNNECTSDINLCGSKGI 2540
Query: 247 CSVSPKGQAQCHCPENYHGD--GMVCLPKDPCTDN 279
C +P G C C + D G C D C N
Sbjct: 2541 CQNTP-GSFTCECQRGFSLDQTGSSCEDVDECEGN 2574
Score = 52.8 bits (125), Expect = 4e-06
Identities = 57/229 (24%), Positives = 83/229 (36%), Gaps = 24/229 (10%)
Query: 1971 CPGGPSSPCSDRGVCMDGMSGSGQCLCRSGFAGTACELCAPGAFGPHCQAC-RCTVHGRC 2029
C GP C C++ +GS +C C+ G+ T+ C CQ HG+C
Sbjct: 1812 CQNGPV--CQRNAECIN-TAGSYRCDCKPGYRFTSTGQCND---RNECQEIPNICSHGQC 1865
Query: 2030 DEGLGGSGSCFCDEGW-TGPRCEVQLELQPVCTPPCAPEAVCR---AGNSCECSLGY-EG 2084
+ + GS C C G+ T + L++ C CR +C C+ G+
Sbjct: 1866 IDTV-GSFYCLCHTGFKTNDDQTMCLDINE-CERDACGNGTCRNTIGSFNCRCNHGFILS 1923
Query: 2085 DGRVCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPDYE--GDGWSCRARNPCTDGHRG 2142
C D C G+G + C C C YE DG +C N C R
Sbjct: 1924 HNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRK 1983
Query: 2143 GCSEHANCLSTGLNTRRCECHAGYVGDGLQCLEESEPPVDRCLGQPPPC 2191
L + RC C GY +C + +D C+ +P C
Sbjct: 1984 CAPGTCQNLD---GSYRCICPPGYSLQNEKCED-----IDECVEEPEIC 2024
Score = 52.4 bits (124), Expect = 6e-06
Identities = 64/248 (25%), Positives = 85/248 (34%), Gaps = 43/248 (17%)
Query: 770 CSNPNK---HGEQCQEDCGCVH-GLCDNRPGSGGVCQQG--TCAPGFSGRFCNESMGDCG 823
CS PN Q CG C+ R +GG C C G+ G C + + + G
Sbjct: 94 CSRPNMCTCPSGQIAPSCGSRSIQHCNIRCMNGGSCSDDHCLCQKGYIGTHCGQPVCESG 153
Query: 824 PTGLAQHCHLHARCVSQEGVARCRCLDGFEGDG----------FSCTPSNPCSHPDRG-G 872
C RCV+ RC C GF G F+ + C G
Sbjct: 154 -------CLNGGRCVAPN---RCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIV 203
Query: 873 CSENAECVP-GSLGTHHCT--------CHKGWSGDGRV--CVAIDECELDMRGGCHTDAL 921
C++ C G H C C +G+ + R C +DEC+ + G C
Sbjct: 204 CTKTLCCATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQA-IPGLCQGGNC 262
Query: 922 CSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGF- 980
+ VG + +C +C ID C G C G V C CPPGF
Sbjct: 263 INTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSS--YFCKCPPGFY 320
Query: 981 -GGDGFSC 987
DG C
Sbjct: 321 TSPDGTRC 328
Score = 50.4 bits (119), Expect = 2e-05
Identities = 48/159 (30%), Positives = 61/159 (38%), Gaps = 33/159 (20%)
Query: 100 CCPGYWGSRCHECPGGAE--TPCNGHGTCLDGM-DRNGTCVCQENFRGSACQECQDPNRF 156
CCPG+ PGG + P H +C DG R C C +
Sbjct: 67 CCPGW-----KTLPGGNQCIVPICRH-SCGDGFCSRPNMCTCPSG-------------QI 107
Query: 157 GPDC--QSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEA 214
P C +S+ C N G D CLC GY G HC Q PVC E C +C A
Sbjct: 108 APSCGSRSIQHCNIRCMNGGSCSDDHCLCQKGYIGTHCGQ--PVC-ESGCLNGGRCVA-P 163
Query: 215 PSCRCLPGYTQQGSECR---APNPCWPSPCSLLAQCSVS 250
C C G+T G +C PC+ + + Q +S
Sbjct: 164 NRCACTYGFT--GPQCERDYRTGPCFTVISNQMCQGQLS 200
Score = 48.5 bits (114), Expect = 8e-05
Identities = 77/330 (23%), Positives = 109/330 (33%), Gaps = 109/330 (33%)
Query: 1329 CEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFH----GTAC-----EVCELGRYGPNC 1379
CE PG VC +G C + GS +C C G G C E C L C
Sbjct: 914 CEVFPG----VCK-NGLCVNT-RGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEEC 967
Query: 1380 TGVCDCAHGLCQEGLQGDGSCVCNVG--WQGLRCDQ--KITSPQ----CPR--------- 1422
T L G +C C+VG W C++ +P+ CPR
Sbjct: 968 T--------LPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEI 1019
Query: 1423 -------------KCDPN----ANCVQDSAGASTCACAAGYS--GNGIFCSEVDPCAHGH 1463
K P+ C +++ G+ C C +G++ C+++D C
Sbjct: 1020 TNGKPFFKDINECKMIPSLCTHGKC-RNTIGSFKCRCDSGFALDSEERNCTDIDECRISP 1078
Query: 1464 GGCSPHANCTKVAPGQRTCTCQDGYMGDGEL---CQEINSC----LIHHGG--------- 1507
C C PG C C +GY + C +I+ C L+ GG
Sbjct: 1079 DLCG-RGQCVNT-PGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSY 1136
Query: 1508 ----------------------CHIHAECIPTGP-----QQVSCSCREGYSGDGIRT-CE 1539
C + A P G + C+C GY R C
Sbjct: 1137 RCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCV 1196
Query: 1540 LLDPCSKNNGGCSPYATCKSTGDGQRTCTC 1569
+D CS NGGC + T +G C+C
Sbjct: 1197 DIDECSIMNGGCETFCT---NSEGSYECSC 1223
Score = 48.5 bits (114), Expect = 8e-05
Identities = 72/318 (22%), Positives = 109/318 (34%), Gaps = 83/318 (26%)
Query: 1330 EPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFH----GTACE----------------- 1368
+ C G G +C +GQC + +GS +C C+EG+ G C
Sbjct: 1932 DECASGNGNLCR-NGQCINT-VGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTC 1989
Query: 1369 ---------VCELGRYGPN--CTGVCDC-------AHGLCQEGLQGDGSCVCNVGWQ--- 1407
+C G N C + +C A G C +G C+C G+
Sbjct: 1990 QNLDGSYRCICPPGYSLQNEKCEDIDECVEEPEICALGTCSN-TEGSFKCLCPEGFSLSS 2048
Query: 1408 -GLRCDQKITSPQCPRKCDPNANCVQDSAGAST--CACAAGYSGNGIFC----SEVDP-- 1458
G RC Q + C K + S S C CA G G C +E D
Sbjct: 2049 SGRRC-QDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAF 2107
Query: 1459 ---CAHGHG------------------GCSPHANCTKVAPGQRTCTCQDGYMGDGELCQE 1497
C +G G H C G C C GY+ G C +
Sbjct: 2108 RQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINT-DGSYRCECPFGYILAGNECVD 2166
Query: 1498 INSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATC 1557
+ C + + + + + G C+C EG+ + TCE ++ C++N C+ C
Sbjct: 2167 TDECSVGNPCGNGTCKNVIGG---FECTCEEGFEPGPMMTCEDINECAQNPLLCA--FRC 2221
Query: 1558 KSTGDGQRTCTCDTAHTV 1575
+T G C C + +
Sbjct: 2222 VNT-YGSYECKCPVGYVL 2238
Score = 48.1 bits (113), Expect = 1e-04
Identities = 92/407 (22%), Positives = 125/407 (30%), Gaps = 119/407 (29%)
Query: 1272 CVNCTRRF--RCTQGFQLQDTPRKSCV-YRSGFSF----------SRGCSYTCAKKIQVP 1318
CVN + C F+L T R CV RSG + CS +
Sbjct: 1502 CVNTPGSYICDCPPDFELNPT-RVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKA 1560
Query: 1319 DCCPGF---FGTLCEPCP------------GGLG--------------------GVCSGH 1343
CC +GT CE CP GG G G+C G
Sbjct: 1561 SCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQG- 1619
Query: 1344 GQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCTGVCDCAHGLCQEGLQGDGSCVCN 1403
G+C + F GS +C C G+ Y T VCD + G+ G G+C
Sbjct: 1620 GKCINTF-GSFQCRCPTGY------------YLNEDTRVCDDVNECETPGICGPGTCYNT 1666
Query: 1404 VG--------------------------------WQGLRCDQKITSPQCPRKC------- 1424
VG CD ++ + C
Sbjct: 1667 VGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIG 1726
Query: 1425 ----DPNANCVQDSAGASTCACAAGYSGNGI-----FCSEVDPCAHGHGGCSPHANCTKV 1475
P C S C + G I ++D C G C + C +
Sbjct: 1727 RAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCE-NGVCINM 1785
Query: 1476 APGQRTCTCQDGYMGDGEL--CQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGD 1533
G C C G+ + +L C++I+ C + C +AECI T C C+ GY
Sbjct: 1786 V-GSFRCECPVGFFYNDKLLVCEDIDECQ-NGPVCQRNAECINTA-GSYRCDCKPGYRFT 1842
Query: 1534 GIRTCELLDPCSKNNGGCSPYATCKSTGDGQRTCTCDTAHTVGDGLT 1580
C + C + CS + C T G C C T D T
Sbjct: 1843 STGQCNDRNECQEIPNICS-HGQCIDT-VGSFYCLCHTGFKTNDDQT 1887
Score = 48.1 bits (113), Expect = 1e-04
Identities = 66/278 (23%), Positives = 96/278 (34%), Gaps = 38/278 (13%)
Query: 100 CCPGYWGSRCHECPGGAETP-----CNGHGTCLDGMDRNGTCVCQENFRGSACQE-CQDP 153
C PGY + +C E C+ HG C+D + + C+C F+ + Q C D
Sbjct: 1835 CKPGYRFTSTGQCNDRNECQEIPNICS-HGQCIDTVG-SFYCLCHTGFKTNDDQTMCLDI 1892
Query: 154 NRFGPDCQSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQELPVCQ----ELRCPQNTQ 209
N D +C +G C + G +C C G+ H + + V + +N Q
Sbjct: 1893 NECERD-----ACGNGTCRN-TIGSFNCRCNHGFILSHNNDCIDVDECASGNGNLCRNGQ 1946
Query: 210 CSAEAPS--CRCLPGY--TQQGSECRAPNPCWPSPCSLLAQCSVSPKGQAQCHCPENYHG 265
C S C+C GY G C N C P + G +C CP Y
Sbjct: 1947 CINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSL 2006
Query: 266 DGMVCLPKDPCTDN-----LGGCPSNSTLCVYQKPGQAFCTCRPG--LVSINSNASAGCF 318
C D C + LG C + G C C G L S
Sbjct: 2007 QNEKCEDIDECVEEPEICALGTCSNTE--------GSFKCLCPEGFSLSSSGRRCQDLRM 2058
Query: 319 AFC-SPFSCDRSATCQVTADGKTSCVCRESEVGDGRAC 355
++C + F + ++ + K C C G G C
Sbjct: 2059 SYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPC 2096
Score = 47.8 bits (112), Expect = 1e-04
Identities = 92/400 (23%), Positives = 137/400 (34%), Gaps = 88/400 (22%)
Query: 628 MAANGVIHMLDG----ILLPPTILPILPKHCSEEQHKIVAGSCVDCQALNTSTCPPNSVK 683
M NG+ DG I P L ++C + G C++ + +NT S +
Sbjct: 581 MCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNGRCVNTD----GSYR 636
Query: 684 LDIFP--------KECVYIH-DPTGLNVLKKG-CASYCNQTIMEQGCC----KGFFGPDC 729
+ FP + CV H T K+G C + + CC + FG C
Sbjct: 637 CECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPC 696
Query: 730 TQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQCQEDCG-CVH 788
CP N + CS G P I +C D C +
Sbjct: 697 QPCPA--QNSAEYQALCSSG----------PGMTSAGSDI--------NECALDPDICPN 736
Query: 789 GLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRC 848
G+C+N G+ + C G+ ++ D L + +C + G C C
Sbjct: 737 GICENLRGT----YKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTC 792
Query: 849 LDGF--EGDGFSCTPSNPCSHPDRGGCSENAECVPG----SLGTHHCTCHKGWSGDGRVC 902
GF + D +C + C E++ C+ G S G+ C C + D
Sbjct: 793 PKGFIYKPDLKTCEDIDEC---------ESSPCINGVCKNSPGSFICECSSESTLDPTKT 843
Query: 903 VAID-------------ECELDMRGGCHTDALCSYVGPGQ-SRCT-CKLG-FAGDGY--- 943
+ I+ CE+++ G CS +G S CT C++ G GY
Sbjct: 844 ICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRI 903
Query: 944 ---QCSPIDPCRAGNGGC-HGLATCRAVGGGQRVCTCPPG 979
QC ID C G C +GL G C CP G
Sbjct: 904 KGTQCEDIDECEVFPGVCKNGLCVNTR---GSFKCQCPSG 940
Score = 46.6 bits (109), Expect = 3e-04
Identities = 55/202 (27%), Positives = 76/202 (37%), Gaps = 37/202 (18%)
Query: 101 CP-GYW--GSRC---HECPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPN 154
CP GY G+ C EC G PC G+GTC + + C C+E F C+D N
Sbjct: 2153 CPFGYILAGNECVDTDECSVG--NPC-GNGTCKNVIG-GFECTCEEGFEPGPMMTCEDIN 2208
Query: 155 RFGPDCQSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQELPVCQ-ELRCPQNT-QCSA 212
Q+ C N G C C GY ++ +C+ E C + C+
Sbjct: 2209 EC---AQNPLLCAFRCVN--TYGSYECKCPVGYV---LREDRRMCKDEDECEEGKHDCTE 2260
Query: 213 EAPSCR---------CLPGYTQQ--GSECRAPNPCWPSPCSLLAQCSVSPKGQAQCHCPE 261
+ C+ C PGY ++ G C N C P ++ +G C C
Sbjct: 2261 KQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCEC-- 2318
Query: 262 NYHGDGMVCLP-KDPCTDNLGG 282
DG P +D C DN G
Sbjct: 2319 ---NDGFTASPNQDECLDNREG 2337
Score = 44.3 bits (103), Expect = 0.002
Identities = 55/219 (25%), Positives = 81/219 (36%), Gaps = 61/219 (27%)
Query: 1967 ECQACPGGPSSPCSDRGVCMDGMSGSGQCLCRSGFAGTACELCAPGAFGPHCQAC-RCTV 2025
EC +PC+ G C++ GS C CR+G+ T C+ C
Sbjct: 487 ECIDVDECEKNPCAG-GECINNQ-GSYTCQCRAGYQSTLTR--------TECRDIDECLQ 536
Query: 2026 HGR-CDEG----LGGSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEAVCRAGNSCECSL 2080
+GR C+ G GS C C+ G+ V R G +CE
Sbjct: 537 NGRICNNGRCINTDGSFHCVCNAGF----------------------HVTRDGKNCE--- 571
Query: 2081 GYEGDGRVCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPDYE--GDGWSCRARNPCTD 2138
D C++ ++C +G C C C P ++ DG C+ N C
Sbjct: 572 ----DMDECSIRNMCLNG--------MCINEDGSFKCICKPGFQLASDGRYCKDINEC-- 617
Query: 2139 GHRGGCSEHANCLSTGLNTRRCECHAGY-VG-DGLQCLE 2175
G + C++T + RCEC G VG DG C++
Sbjct: 618 -ETPGICMNGRCVNTD-GSYRCECFPGLAVGLDGRVCVD 654
Score = 43.5 bits (101), Expect = 0.003
Identities = 80/349 (22%), Positives = 108/349 (30%), Gaps = 93/349 (26%)
Query: 47 CAAIKKQTCPSGWLRELPDQITQDCR--YEVQLGG-SMVSMSGCR---RKCRKQVVQKA- 99
CA+ C +G C YEV G + V ++ C RKC Q
Sbjct: 1934 CASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLD 1993
Query: 100 ------CCPGY--WGSRCHECPGGAETP--CNGHGTCLDGMDRNGTCVCQENFR----GS 145
C PGY +C + E P C GTC + + C+C E F G
Sbjct: 1994 GSYRCICPPGYSLQNEKCEDIDECVEEPEIC-ALGTC-SNTEGSFKCLCPEGFSLSSSGR 2051
Query: 146 ACQE--------------CQDPNRFGPDCQSVCSCVHG--------VCNHGPRGDGSCLC 183
CQ+ C P Q C + G +C P +C
Sbjct: 2052 RCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQIC 2111
Query: 184 FAG---YTGPHCDQ-ELPVCQELRCPQNTQCSAEAPS--CRCLPGYTQQGS------ECR 231
G GP ++ C+E ++ QC S C C GY G+ EC
Sbjct: 2112 PYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYILAGNECVDTDECS 2171
Query: 232 APNPCW--------------------PSP---CSLLAQCSVSP----------KGQAQCH 258
NPC P P C + +C+ +P G +C
Sbjct: 2172 VGNPCGNGTCKNVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECK 2231
Query: 259 CPENY--HGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPG 305
CP Y D +C +D C + C C G C C PG
Sbjct: 2232 CPVGYVLREDRRMCKDEDECEEGKHDCTEKQMEC-KNLIGTYMCICGPG 2279
Score = 43.1 bits (100), Expect = 0.004
Identities = 63/247 (25%), Positives = 90/247 (36%), Gaps = 44/247 (17%)
Query: 709 SYCNQTIMEQGCCKG--FFGPDCTQCPGGFSNP-C---YGKGNCSDGIQGNGACLCFPDY 762
++C Q + E GC G P+ C GF+ P C Y G C I +C
Sbjct: 143 THCGQPVCESGCLNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQ---MCQGQL 199
Query: 763 KGIACHICSNPNKHGEQCQEDCGCVHG-LCDNRPGSGGVCQQGTCAPGFSGRFCNESMGD 821
GI C C G G C+ P C++G P C +
Sbjct: 200 SGIVC--------TKTLCCATVGRAWGHPCEMCPAQPHPCRRG-FIPNIRTGACQDVDEC 250
Query: 822 CGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGDGFS--CTPSNPCSHPDRGGCSENAEC 879
GL Q C++ G C+C G + + S C + CS G E EC
Sbjct: 251 QAIPGLCQ----GGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECS--TIPGICEGGEC 304
Query: 880 VPGSLGTHHCTCHKGW--SGDGRVCVAIDECELDMRGG-CH---TDALCSYVGP---GQS 930
++ ++ C C G+ S DG C+ D+R G C+ T+ CS P +
Sbjct: 305 T-NTVSSYFCKCPPGFYTSPDGTRCI-------DVRPGYCYTALTNGRCSNQLPQSITKM 356
Query: 931 RCTCKLG 937
+C C G
Sbjct: 357 QCCCDAG 363
Score = 40.8 bits (94), Expect = 0.017
Identities = 52/190 (27%), Positives = 72/190 (37%), Gaps = 33/190 (17%)
Query: 126 CLDGMDRNG----TCVCQENFRGSA-CQECQDPNRFGPDCQSVCSCVHGVCNHGPRGDGS 180
C +G RN C C + F + C+D + +C+S C++GVC + P G
Sbjct: 776 CDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDID----ECES-SPCINGVCKNSP-GSFI 829
Query: 181 CLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAPSCRC---LPGYTQQGSECRAPNPCW 237
C C + T D +C E C RC + G T + C + W
Sbjct: 830 CECSSEST---LDPTKTICIETI---KGTCWQTVIDGRCEININGATLKSQCCSSLGAAW 883
Query: 238 PSPCSLLAQCSVSPKGQAQCHCPENYHG-DGMVCLPKDPCTDNLGGCPSNSTLCVYQKPG 296
SPC+L C V P C + Y G C D C G C + LCV + G
Sbjct: 884 GSPCTL---CQVDP------ICGKGYSRIKGTQCEDIDECEVFPGVCKNG--LCVNTR-G 931
Query: 297 QAFCTCRPGL 306
C C G+
Sbjct: 932 SFKCQCPSGM 941
Score = 38.9 bits (89), Expect = 0.066
Identities = 49/189 (25%), Positives = 66/189 (34%), Gaps = 65/189 (34%)
Query: 854 GDGFSCTPSNPCSHPD---RGGCSE------NAECVPG-SLGTHHCTCHKGWSG------ 897
GDGF C+ N C+ P C N C+ G S HC C KG+ G
Sbjct: 90 GDGF-CSRPNMCTCPSGQIAPSCGSRSIQHCNIRCMNGGSCSDDHCLCQKGYIGTHCGQP 148
Query: 898 -------DGRVCVAID-----------ECELDMRGGCHTDALCSYVGPGQ--------SR 931
+G CVA + +CE D R G + + + GQ +
Sbjct: 149 VCESGCLNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTL 208
Query: 932 CTCKLGFAGDGYQC----SPIDPCRAG------NGGCHGLATCRAVGG-----------G 970
C +G A G+ C + PCR G G C + C+A+ G G
Sbjct: 209 CCATVGRAW-GHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVG 267
Query: 971 QRVCTCPPG 979
C CP G
Sbjct: 268 SFECKCPAG 276
Score = 38.9 bits (89), Expect = 0.066
Identities = 55/216 (25%), Positives = 82/216 (37%), Gaps = 37/216 (17%)
Query: 1983 GVCMDGMSGSGQCLCRSGFA--GTACELCAPGAFGPHCQACRCTVHGRCDEGLGGSGSCF 2040
G C + + GS +C+C G++ CE P A G C GS C
Sbjct: 1987 GTCQN-LDGSYRCICPPGYSLQNEKCEDIDECVEEPEICAL-----GTCSN-TEGSFKCL 2039
Query: 2041 CDEGWT----GPRCEVQLELQPVCTP----PCA-PEAVCRAGNSCECSLGYEGDGRVCTV 2091
C EG++ G RC+ L + C+ P++ + C C+L EG G C
Sbjct: 2040 CPEGFSLSSSGRRCQ-DLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPC-- 2096
Query: 2092 ADLCQDGHGGCSEHANCSQVGTMVTCTCLPDYEG-DGWSCRARNPCTDGHRGGCSEHANC 2150
+LC G +V PD D C+ + C +H C
Sbjct: 2097 -ELCPTEPDEAFRQICPYGSGIIVG----PDDSAVDMDECKEPDVC---------KHGQC 2142
Query: 2151 LSTGLNTRRCECHAGYVGDGLQCLEESEPPVDRCLG 2186
++T + RCEC GY+ G +C++ E V G
Sbjct: 2143 INTD-GSYRCECPFGYILAGNECVDTDECSVGNPCG 2177
Score = 36.6 bits (83), Expect = 0.33
Identities = 58/249 (23%), Positives = 89/249 (35%), Gaps = 35/249 (14%)
Query: 1966 SECQACPGGPSSPCSDRGVCMDGMSGSGQCLCRSGFAGTACELCAPGAFGPHCQACRCTV 2025
+EC+ P S C+ G C + + GS +C C SGFA + E C
Sbjct: 1030 NECKMIP----SLCT-HGKCRNTI-GSFKCRCDSGFALDSEERNCTDIDECRISPDLCG- 1082
Query: 2026 HGRCDEGLGGSGSCFCDEGWTGPRCEVQ--LELQPVCTPPCAPEAVCRAG--------NS 2075
G+C G C CDEG+ ++ +++ P +CR G
Sbjct: 1083 RGQC-VNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDP----LLCRGGVCHNTEGSYR 1137
Query: 2076 CECSLGYEGDGRVCTVADL--CQDGHGGCSEHANCSQVGTMVTCTCLPDYEG--DGWSCR 2131
CEC G++ + D+ C+ C + C + C C P Y D C
Sbjct: 1138 CECPPGHQLSPNISACIDINECELSAHLC-PNGRCVNLIGKYQCACNPGYHSTPDRLFCV 1196
Query: 2132 ARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGDGLQCLEESEPPVDRCLGQPPPC 2191
+ C+ GGC + + C C G+ L + S +D C P C
Sbjct: 1197 DIDECSI-MNGGCETFC---TNSEGSYECSCQPGF---ALMPDQRSCTDIDECEDNPNIC 1249
Query: 2192 HSDAMCTDL 2200
CT++
Sbjct: 1250 -DGGQCTNI 1257
Score = 34.7 bits (78), Expect = 1.2
Identities = 66/265 (24%), Positives = 97/265 (36%), Gaps = 60/265 (22%)
Query: 1960 CPGHYGSECQA-CPGGPS--------SPCS-DRGVCMDG----MSGSGQCLCRSGFAGTA 2005
CP +E QA C GP + C+ D +C +G + G+ +C+C SG+
Sbjct: 699 CPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICENLRGTYKCICNSGY---- 754
Query: 2006 CELCAPGAFGPHC-QACRCTVHG-RCDEG----LGGSGSCFCDEGWT-GPRCEVQLELQP 2058
+ G +C C ++ CD G GS C C +G+ P + ++
Sbjct: 755 ----EVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDE 810
Query: 2059 VCTPPCAPEAVCRAGNS---CECSLGYEGD--GRVC--TVADLCQDG--HGGCSEHAN-- 2107
+ PC VC+ CECS D +C T+ C G C + N
Sbjct: 811 CESSPCI-NGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGA 869
Query: 2108 ------CSQVGTMVTCTC----LPDYEGDGWSCRARNPCTDGHRGGCSEHANCLSTGL-- 2155
CS +G C + G G+S C D C GL
Sbjct: 870 TLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDE--CEVFPGVCKNGLCV 927
Query: 2156 NTR---RCECHAGYVGD--GLQCLE 2175
NTR +C+C +G D G CL+
Sbjct: 928 NTRGSFKCQCPSGMTLDATGRICLD 952
Score = 34.7 bits (78), Expect = 1.2
Identities = 67/293 (22%), Positives = 96/293 (32%), Gaps = 53/293 (18%)
Query: 32 CDVKTTFVTHVPCTSCAAIKKQTCPS----GWLRELPDQITQDCRYEVQL---GGSMVSM 84
C+ FV +C I + + P+ G LP +C +L GG+ +
Sbjct: 1429 CECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDV 1488
Query: 85 SGCRRKCRKQVVQKACCPGYWGSRCHECPGGAETPCNGHGTCLDGMDRNGTCVCQENFRG 144
+ C C GS +CP E G C+D R+G C RG
Sbjct: 1489 NEC---LDPTTCISGNCVNTPGSYICDCPPDFELNPTRVG-CVD--TRSGNCYLDIRPRG 1542
Query: 145 ----SACQECQDPNRFGPDCQSVCSCVHGVCNHGPRGDGSC-LCFAGYTGPHCDQELPVC 199
+AC N G C C+ G C +C A T + P
Sbjct: 1543 DNGDTACS-----NEIGVGVSKASCC----CSLGKAWGTPCEMCPAVNTSEY-KILCPGG 1592
Query: 200 QELRCPQNTQCSAEAPSCRCLPGYTQQGSECRAPNPCWPSPCSLLAQCSVSPKGQAQCHC 259
+ R T + C+ LPG Q G +C ++ G QC C
Sbjct: 1593 EGFRPNPITVILEDIDECQELPGLCQ-GGKC------------------INTFGSFQCRC 1633
Query: 260 PENYH--GDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPGLVSIN 310
P Y+ D VC + C + G C + Y G C C P + +N
Sbjct: 1634 PTGYYLNEDTRVCDDVNEC-ETPGICGPGT---CYNTVGNYTCICPPDYMQVN 1682
>gi|122937343 platelet endothelial aggregation receptor 1 [Homo
sapiens]
Length = 1037
Score = 112 bits (280), Expect = 5e-24
Identities = 93/300 (31%), Positives = 117/300 (39%), Gaps = 69/300 (23%)
Query: 720 CCKGFFGPDCTQ--CPGGFSN-----PCYGKGNCSDGIQG-NGACLCFPDYKGIACHICS 771
C GF G CT CP GF PC S NG C C P + G+ C+
Sbjct: 336 CEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNESC 395
Query: 772 NPNKHGEQCQEDCGCVH-GLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQH 830
+ HG CQE C C+H G+C + G+CQ CAPG++G C C P +
Sbjct: 396 PQDTHGPGCQEHCLCLHGGVCQ---ATSGLCQ---CAPGYTGPHCASL---CPPDTYGVN 446
Query: 831 CHLHARCVSQEGVA------RCRCLDGFEGD-----------GFSCTPSNPCSH-----P 868
C ARC + +A C C +G++ GFSC S C+H P
Sbjct: 447 C--SARCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVCSP 504
Query: 869 DRGGCSENAECVPGSLGTH-HCTCHKGWSGDGRVCVAIDECELDMRGGCHTDALCSYVGP 927
G C+ C PG G H C KG G+G C+ D GC P
Sbjct: 505 QTGACT----CTPGWHGAHCQLPCPKGQFGEG----CASRCDCDHSDGC---------DP 547
Query: 928 GQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRV-----CTCPPGFGG 982
RC C+ G+ G S C G G + TC GG + C C PGF G
Sbjct: 548 VHGRCQCQAGWMGARCHLS----CPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRG 603
Score = 104 bits (260), Expect = 1e-21
Identities = 84/277 (30%), Positives = 113/277 (40%), Gaps = 42/277 (15%)
Query: 1320 CCPGFFGTLCE-PCPGGLGGV-CSGHGQCQ-----DRFLGSGECHCHEGFHGTAC-EVCE 1371
C PG+ GT+C PCP G G CS +C DRF +G+C C G+ G C E C
Sbjct: 250 CPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLCDRF--TGQCRCAPGYTGDRCREECP 307
Query: 1372 LGRYGPNCTGVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKI-------TSPQCPRKC 1424
+GR+G +C CDCA +G+C+C G+ G RC ++ S Q P C
Sbjct: 308 VGRFGQDCAETCDCAPD--ARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTC 365
Query: 1425 DPNANCVQDSAGASTCACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRT--- 1481
D + + C+C G++ G+ C+E P GC H C Q T
Sbjct: 366 D-REHSLSCHPMNGECSCLPGWA--GLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSGL 422
Query: 1482 CTCQDGYMGDGELCQEINSCLIHHGGCHIHAEC---IPTGPQQVSCSCREGYSGDGIRTC 1538
C C GY G C + + C C I P C C+EG+ C
Sbjct: 423 CQCAPGYTGPH--CASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRG---NC 477
Query: 1539 ELLDPCSKNNGGCSPYATCK-------STGDGQRTCT 1568
+ PC G S A+C+ S G TCT
Sbjct: 478 SV--PCPPGTWGFSCNASCQCAHEAVCSPQTGACTCT 512
Score = 102 bits (254), Expect = 5e-21
Identities = 98/333 (29%), Positives = 128/333 (38%), Gaps = 71/333 (21%)
Query: 54 TCPSGWLREL-----PD-----QITQDCRYEVQLGGSMVSMSGCRRKCRKQVVQKACCPG 103
+CP GW+ + P+ +Q+CR GG +G +CR C PG
Sbjct: 249 SCPPGWMGTICSLPCPEGFHGPNCSQECR--CHNGGLCDRFTG---QCR-------CAPG 296
Query: 104 YWGSRC-HECPGG------AET-PCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNR 155
Y G RC ECP G AET C C NG C+C+ F G C + P+
Sbjct: 297 YTGDRCREECPVGRFGQDCAETCDCAPDARCFPA---NGACLCEHGFTGDRCTDRLCPDG 353
Query: 156 F-GPDCQSVCSC--VHGVCNHGPRGDGSCLCFAGYTGPHCDQELPV------CQE-LRCP 205
F G CQ+ C+C H + H G+ C C G+ G HC++ P CQE C
Sbjct: 354 FYGLSCQAPCTCDREHSLSCHPMNGE--CSCLPGWAGLHCNESCPQDTHGPGCQEHCLCL 411
Query: 206 QNTQCSAEAPSCRCLPGYTQQGSECRAPNPCWPSPCSLLAQC----SVSPKGQAQCHCPE 261
C A + C+C PGYT P + CS C + SP +C C E
Sbjct: 412 HGGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPI-DGECVCKE 470
Query: 262 NY-HGDGMVCLPKDPCTDNLGGCPSN-STLCVYQ---KPGQAFCTCRPG-------LVSI 309
+ G+ V PC G N S C ++ P CTC PG L
Sbjct: 471 GWQRGNCSV-----PCPPGTWGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCP 525
Query: 310 NSNASAGCFAFCSPFSCDRSATCQVTADGKTSC 342
GC + C CD S C G+ C
Sbjct: 526 KGQFGEGCASRC---DCDHSDGCD-PVHGRCQC 554
Score = 99.4 bits (246), Expect = 4e-20
Identities = 98/348 (28%), Positives = 134/348 (38%), Gaps = 82/348 (23%)
Query: 1257 SSRCLHSHAEALREKCVNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRGCSYT----CA 1312
S+RC +A A C C +G+Q + GFS + C C+
Sbjct: 448 SARCSCENAIACSPIDGECV----CKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVCS 503
Query: 1313 KKIQVPDCCPGFFGTLCE-PCPGG-LGGVCSGHGQCQDRFLGS----GECHCHEGFHGTA 1366
+ C PG+ G C+ PCP G G C+ C D G G C C G+ G
Sbjct: 504 PQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDC-DHSDGCDPVHGRCQCQAGWMGAR 562
Query: 1367 CEV-CELGRYGPNCTGVCDCAHG-LCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKC 1424
C + C G +G NC+ C C +G C L +G+CVC G++G C + + ++C
Sbjct: 563 CHLSCPEGLWGVNCSNTCTCKNGGTC---LPENGNCVCAPGFRGPSCQRSCQPGRYGKRC 619
Query: 1425 DPNANCVQDS---AGASTCACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRT 1481
P C S TC C AG++G CS+ PC GH G NC +T
Sbjct: 620 VP-CKCANHSFCHPSNGTCYCLAGWTGPD--CSQ--PCPPGHWG----ENCA------QT 664
Query: 1482 CTCQDGYMGDGELCQEINSCLIHHGG-CHIHAECIPTGPQQVSCSCREGYSGDGIRTCEL 1540
C C HHGG CH PQ SC C G++G
Sbjct: 665 CQC-------------------HHGGTCH---------PQDGSCICPLGWTGH-----HC 691
Query: 1541 LDPCSKNNGGCSPYATCKSTGDGQR------TCTCDTAHTVGDGLTCR 1582
L+ C G + C+ G G++ C C H+ G CR
Sbjct: 692 LEGCPLGTFGANCSQPCQ-CGPGEKCHPETGACVCPPGHS---GAPCR 735
Score = 93.2 bits (230), Expect = 3e-18
Identities = 81/256 (31%), Positives = 103/256 (40%), Gaps = 44/256 (17%)
Query: 1959 CCPGHYGSEC-QACPGGPSSPCSDRGVCMDGMSGSGQCLCRSGFAGTAC-ELCAPGAFGP 2016
C PG +G +C + C G +S C + SG C C SG C + C PG +GP
Sbjct: 135 CAPGMWGPQCDKPCSCGNNSSCDPK---------SGVCSCPSGLQPPNCLQPCTPGYYGP 185
Query: 2017 HCQACRCTVHGR-CDEGLGGSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEAVCRAG-- 2073
CQ RC HG CD +G+CFC TGP C+V Q C C+ G
Sbjct: 186 ACQF-RCQCHGAPCDPQ---TGACFCPAERTGPSCDVSCS-QGTSGFFCPSTHSCQNGGV 240
Query: 2074 -----NSCECSLGYEGDGRVCTVADLCQDG-HG-GCSEHANCSQVGT----MVTCTCLPD 2122
SC C G+ G +C++ C +G HG CS+ C G C C P
Sbjct: 241 FQTPQGSCSCPPGWM--GTICSLP--CPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPG 296
Query: 2123 YEGDGWSCRARNPCTDGHRG-GCSEHANCLSTGL---NTRRCECHAGYVGDGLQCLEESE 2178
Y GD R R C G G C+E +C C C G+ GD +C +
Sbjct: 297 YTGD----RCREECPVGRFGQDCAETCDCAPDARCFPANGACLCEHGFTGD--RCTDRLC 350
Query: 2179 PPVDRCLGQPPPCHSD 2194
P L PC D
Sbjct: 351 PDGFYGLSCQAPCTCD 366
Score = 92.8 bits (229), Expect = 4e-18
Identities = 102/365 (27%), Positives = 126/365 (34%), Gaps = 123/365 (33%)
Query: 718 QGCCKGFFGPDCT---QCPGGFSNPCYGKG-------------NCSDGIQG--------- 752
Q C G++GP C QC G +P G +CS G G
Sbjct: 176 QPCTPGYYGPACQFRCQCHGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSC 235
Query: 753 ---------NGACLCFPDYKGIACHICSNPNKHGEQCQEDCGCVH-GLCDNRPGSGGVCQ 802
G+C C P + G C + HG C ++C C + GLCD G
Sbjct: 236 QNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTG------ 289
Query: 803 QGTCAPGFSGRFCNESM------GDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGD- 855
Q CAPG++G C E DC T C ARC G C C GF GD
Sbjct: 290 QCRCAPGYTGDRCREECPVGRFGQDCAET---CDCAPDARCFPANGA--CLCEHGFTGDR 344
Query: 856 -----------GFSCTPSNPCS-------HPDRGGCSENAECVPGSLGTH---------- 887
G SC C HP G CS C+PG G H
Sbjct: 345 CTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECS----CLPGWAGLHCNESCPQDTH 400
Query: 888 ------HCTCHKGWSGDGRVCVAIDECELDMRGGCHTDALC---SYVGPGQSRCTCKLGF 938
HC C G G + + +C G H +LC +Y +RC+C+
Sbjct: 401 GPGCQEHCLCLHG--GVCQATSGLCQCAPGYTGP-HCASLCPPDTYGVNCSARCSCENAI 457
Query: 939 AGDGYQCSPID----------------PCRAGNGGCHGLATCR----AVGGGQR-VCTCP 977
A CSPID PC G G A+C+ AV Q CTC
Sbjct: 458 A-----CSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVCSPQTGACTCT 512
Query: 978 PGFGG 982
PG+ G
Sbjct: 513 PGWHG 517
Score = 89.7 bits (221), Expect = 3e-17
Identities = 74/235 (31%), Positives = 91/235 (38%), Gaps = 59/235 (25%)
Query: 1939 PQG-LGRGCHRNCVTTTWKPSCCPGHYGSECQA----------CPGGP-SSPCSDRGVCM 1986
P+G G GC C C P H +CQA CP G CS+ C
Sbjct: 525 PKGQFGEGCASRC-DCDHSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCK 583
Query: 1987 DG---MSGSGQCLCRSGFAGTACEL-CAPGAFGPHCQACRCTVHGRCDEGLGGSGSCFCD 2042
+G + +G C+C GF G +C+ C PG +G C C+C H C +G+C+C
Sbjct: 584 NGGTCLPENGNCVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSFCHP---SNGTCYCL 640
Query: 2043 EGWTGPRCEVQLELQPVCTP-----PCAPEAVCRAG-------NSCECSLGYEGDGRVCT 2090
GWTGP C QP C P CA C G SC C LG+ G
Sbjct: 641 AGWTGPDCS-----QP-CPPGHWGENCAQTCQCHHGGTCHPQDGSCICPLGWTGHH---- 690
Query: 2091 VADLCQDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWSCRARN---PCTDGHRG 2142
C +G + ANCSQ C C G G C C GH G
Sbjct: 691 ----CLEGCPLGTFGANCSQ-----PCQC-----GPGEKCHPETGACVCPPGHSG 731
Score = 89.7 bits (221), Expect = 3e-17
Identities = 53/164 (32%), Positives = 73/164 (44%), Gaps = 23/164 (14%)
Query: 78 GGSMVSMSG---CRRKCRKQVVQKACCPGYWGSRCHECPGGAETPCNGHGTCLDGMDRNG 134
GG+ + +G C R Q++C PG +G RC C C H C NG
Sbjct: 585 GGTCLPENGNCVCAPGFRGPSCQRSCQPGRYGKRCVPCK------CANHSFCHPS---NG 635
Query: 135 TCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQ 194
TC C + G C + P +G +C C C HG H DGSC+C G+TG HC +
Sbjct: 636 TCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQ--DGSCICPLGWTGHHCLE 693
Query: 195 ELPV-------CQELRCPQNTQCSAEAPSCRCLPGYTQQGSECR 231
P+ Q +C +C E +C C PG++ G+ CR
Sbjct: 694 GCPLGTFGANCSQPCQCGPGEKCHPETGACVCPPGHS--GAPCR 735
Score = 89.0 bits (219), Expect = 6e-17
Identities = 90/289 (31%), Positives = 115/289 (39%), Gaps = 51/289 (17%)
Query: 1928 SVWVHPSLWGRPQGLGRGCHRN--CVTTTWKPSCCPGHYGSECQ-ACPGGP-SSPCSDRG 1983
SV P WG C C T +C PG +G+ CQ CP G C+ R
Sbjct: 478 SVPCPPGTWGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRC 537
Query: 1984 VC--MDGMSG-SGQCLCRSGFAGTACEL-CAPGAFGPHC-QACRCTVHGRCDEGLGGSGS 2038
C DG G+C C++G+ G C L C G +G +C C C G C L +G+
Sbjct: 538 DCDHSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTC---LPENGN 594
Query: 2039 CFCDEGWTGPRCEVQLELQP-----VCTP-PCAPEAVCRAGN-SCECSLGYEGDGRVCTV 2091
C C G+ GP C Q QP C P CA + C N +C C G+ G
Sbjct: 595 CVCAPGFRGPSC--QRSCQPGRYGKRCVPCKCANHSFCHPSNGTCYCLAGWTGP----DC 648
Query: 2092 ADLCQDGHGG--CSEHANCSQVGTMVTCTCLPDYEGDGWSCRARNPCTDGHRGGCSEHAN 2149
+ C GH G C++ C G TC P DG SC T H C E
Sbjct: 649 SQPCPPGHWGENCAQTCQCHHGG-----TCHPQ---DG-SCICPLGWTGHH---CLEGCP 696
Query: 2150 CLSTGLN-TRRCECHAGYVGDGLQCLEESEPPVDRCLGQPPPCHSDAMC 2197
+ G N ++ C+C G E+ P C+ PP HS A C
Sbjct: 697 LGTFGANCSQPCQCGPG---------EKCHPETGACV--CPPGHSGAPC 734
Score = 88.6 bits (218), Expect = 7e-17
Identities = 100/350 (28%), Positives = 126/350 (36%), Gaps = 79/350 (22%)
Query: 1958 SCCPGHYGSECQA-CPGGPSSP-CSDRGVCMDGM---SGSGQCLCRSGFAGTAC-ELCAP 2011
SC PG G+ C CP G P CS C +G +GQC C G+ G C E C
Sbjct: 249 SCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGYTGDRCREECPV 308
Query: 2012 GAFGPHC-QACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQ--------LELQPVCTP 2062
G FG C + C C RC +G+C C+ G+TG RC + L Q CT
Sbjct: 309 GRFGQDCAETCDCAPDARC---FPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTC 365
Query: 2063 PCAPEAVCRAGN-SCECSLGYEGDGRVCTVADLC-QDGHG-GCSEHANCSQVG----TMV 2115
C N C C G+ G + C QD HG GC EH C G T
Sbjct: 366 DREHSLSCHPMNGECSCLPGWAG----LHCNESCPQDTHGPGCQEHCLCLHGGVCQATSG 421
Query: 2116 TCTCLPDYEGD-----------GWSCRARNPCTDG----------------HRGGCSE-- 2146
C C P Y G G +C AR C + RG CS
Sbjct: 422 LCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPC 481
Query: 2147 ---------HANCLST-----GLNTRRCECHAGYVGDGLQCLEESEPPVDRCLGQPPPCH 2192
+A+C T C C G+ G Q + C + H
Sbjct: 482 PPGTWGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDH 541
Query: 2193 SDAMCTDLHFQ-EKRAGVF----HLQATSGPYGLNFSEAEAACEAQGAVL 2237
SD C +H + + +AG HL G +G+N S C+ G L
Sbjct: 542 SDG-CDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNT-CTCKNGGTCL 589
Score = 81.3 bits (199), Expect = 1e-14
Identities = 86/330 (26%), Positives = 117/330 (35%), Gaps = 90/330 (27%)
Query: 720 CCKGFFGPDCTQC--PGGFSNPCYGKGNCSDGIQGN---GACLCFPDYKGIACHICSNPN 774
C G+ GP C P + C + +C + I + G C+C ++ C + P
Sbjct: 425 CAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPG 484
Query: 775 KHGEQCQEDCGCVH-GLCDNRPGSGGVCQQGTCAPGFSGRFCNESM--GDCGPTGLAQHC 831
G C C C H +C + G+ C TC PG+ G C G G G A C
Sbjct: 485 TWGFSCNASCQCAHEAVCSPQTGA---C---TCTPGWHGAHCQLPCPKGQFGE-GCASRC 537
Query: 832 H---------LHARCVSQEGV--ARCR--CLDGFEG----------DGFSCTPSNP---C 865
+H RC Q G ARC C +G G +G +C P N C
Sbjct: 538 DCDHSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGNCVC 597
Query: 866 SHPDRG-GCSENAE-------CVPGSLGTHH--------CTCHKGWSGD----------- 898
+ RG C + + CVP H C C GW+G
Sbjct: 598 APGFRGPSCQRSCQPGRYGKRCVPCKCANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHW 657
Query: 899 GRVCVAIDECELDMRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGC 958
G C C+ G CH P C C LG+ G + C ++ C G G
Sbjct: 658 GENCA--QTCQCHHGGTCH---------PQDGSCICPLGWTG--HHC--LEGCPLGTFGA 702
Query: 959 HGLATCRAVGGGQR------VCTCPPGFGG 982
+ C+ G G++ C CPPG G
Sbjct: 703 NCSQPCQC-GPGEKCHPETGACVCPPGHSG 731
Score = 80.5 bits (197), Expect = 2e-14
Identities = 65/250 (26%), Positives = 93/250 (37%), Gaps = 47/250 (18%)
Query: 91 CRKQVVQKACCPGYWGSRCH-ECPGGA-ETPCNGHGTC--LDGMDR-NGTCVCQENFRGS 145
C Q C PG+ G+ C CP G C C DG D +G C CQ + G+
Sbjct: 502 CSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGA 561
Query: 146 ACQECQDPNRFGPDCQSVCSCVHG-VCNHGPRGDGSCLCFAGYTGPHCDQELPV------ 198
C +G +C + C+C +G C +G+C+C G+ GP C +
Sbjct: 562 RCHLSCPEGLWGVNCSNTCTCKNGGTCLPE---NGNCVCAPGFRGPSCQRSCQPGRYGKR 618
Query: 199 CQELRCPQNTQCSAEAPSCRCLPGYTQQGSECRAPNP--CWPSPCSLLAQC---SVSPKG 253
C +C ++ C +C CL G+T G +C P P W C+ QC
Sbjct: 619 CVPCKCANHSFCHPSNGTCYCLAGWT--GPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQ 676
Query: 254 QAQCHCPENYHGDGMV-----------------CLPKDPCTDNLGGCPSNSTLCVYQKPG 296
C CP + G + C P + C G C +C PG
Sbjct: 677 DGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEKCHPETGAC-----VC---PPG 728
Query: 297 QAFCTCRPGL 306
+ CR G+
Sbjct: 729 HSGAPCRIGI 738
Score = 77.4 bits (189), Expect = 2e-13
Identities = 72/248 (29%), Positives = 92/248 (37%), Gaps = 51/248 (20%)
Query: 720 CCKGFFGPDCT-QCPGG-FSNPCYGKGNC--SDGIQG-NGACLCFPDYKGIACHICSNPN 774
C G+ G C CP G F C + +C SDG +G C C + G CH+
Sbjct: 511 CTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGARCHLSCPEG 570
Query: 775 KHGEQCQEDCGCVHGLCDNRPGSGGVC--QQGTC--APGFSGRFCNESM--GDCGPTGLA 828
G C C C +G G C + G C APGF G C S G G +
Sbjct: 571 LWGVNCSNTCTCKNG---------GTCLPENGNCVCAPGFRGPSCQRSCQPGRYGKRCVP 621
Query: 829 QHCHLHARCVSQEGVARCRCLDGFEGDGFSCTPSNPCSHPDRG-GCSENAECVPGSLGTH 887
C H+ C G C CL G+ G C S PC G C++ +C G GT
Sbjct: 622 CKCANHSFCHPSNGT--CYCLAGWTGP--DC--SQPCPPGHWGENCAQTCQCHHG--GTC 673
Query: 888 H-----CTCHKGWSGDGRVCVAIDECELDMRGG-------------CHTDALCSYVGPGQ 929
H C C GW+G ++ C L G CH + PG
Sbjct: 674 HPQDGSCICPLGWTGHH----CLEGCPLGTFGANCSQPCQCGPGEKCHPETGACVCPPGH 729
Query: 930 SRCTCKLG 937
S C++G
Sbjct: 730 SGAPCRIG 737
Score = 73.6 bits (179), Expect = 2e-12
Identities = 81/311 (26%), Positives = 112/311 (36%), Gaps = 84/311 (27%)
Query: 1320 CCPGFFGT--LCEPCPGGLGGVCSG---HGQCQDRFLGSGECHCHEGFHGTACEV-CELG 1373
CC GF+ + C P +C+ HG+C + +C C G+ G C C G
Sbjct: 90 CCHGFYESRGFCVP-------LCAQECVHGRC----VAPNQCQCVPGWRGDDCSSECAPG 138
Query: 1374 RYGPNCTGVCDCAHG----------LCQEGLQGDGSCV--CNVGWQGLRCDQKITSPQCP 1421
+GP C C C + C GLQ +C+ C G+ G C + P
Sbjct: 139 MWGPQCDKPCSCGNNSSCDPKSGVCSCPSGLQ-PPNCLQPCTPGYYGPACQFRCQCHGAP 197
Query: 1422 RKCDPNAN---CVQDSAGASTCACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPG 1478
CDP C + G S C + +G FC C +G +P +C+ PG
Sbjct: 198 --CDPQTGACFCPAERTGPS-CDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCS-CPPG 253
Query: 1479 QR----TCTCQDGYMGDGELCQEINSCLIHHGG-CHIHAECIPTGPQQVSCSCREGYSGD 1533
+ C +G+ G C + C H+GG C TG C C GY+GD
Sbjct: 254 WMGTICSLPCPEGFHGPN--CSQ--ECRCHNGGLCDRF-----TG----QCRCAPGYTGD 300
Query: 1534 GIR--------------TCELLDP--CSKNNGGC-------SPYATCKSTGDG------Q 1564
R TC+ C NG C T + DG Q
Sbjct: 301 RCREECPVGRFGQDCAETCDCAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQ 360
Query: 1565 RTCTCDTAHTV 1575
CTCD H++
Sbjct: 361 APCTCDREHSL 371
Score = 71.6 bits (174), Expect = 9e-12
Identities = 73/260 (28%), Positives = 98/260 (37%), Gaps = 56/260 (21%)
Query: 665 SC-VDCQALNTSTCPPNSVKLDIFPK-ECVYIHDPTGLNVLKKGCASYCNQTIME----- 717
SC CQ + + C P + P + P +GCAS C+ +
Sbjct: 489 SCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPV 548
Query: 718 QGCCK---GFFGPDC-TQCPGGF-----SNPCYGK--GNCSDGIQGNGACLCFPDYKGIA 766
G C+ G+ G C CP G SN C K G C + NG C+C P ++G +
Sbjct: 549 HGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTC---LPENGNCVCAPGFRGPS 605
Query: 767 CHICSNPNKHGEQCQEDCGCV-HGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGP- 824
C P ++G++C C C H C S G C C G++G C++ C P
Sbjct: 606 CQRSCQPGRYGKRC-VPCKCANHSFCH---PSNGTCY---CLAGWTGPDCSQ---PCPPG 655
Query: 825 ---TGLAQHCHLH--ARCVSQEGVARC-------RCLDGFEGDGFSCTPSNPCS------ 866
AQ C H C Q+G C CL+G F S PC
Sbjct: 656 HWGENCAQTCQCHHGGTCHPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEK 715
Query: 867 -HPDRGGCSENAECVPGSLG 885
HP+ G C C PG G
Sbjct: 716 CHPETGAC----VCPPGHSG 731
Score = 67.0 bits (162), Expect = 2e-10
Identities = 90/342 (26%), Positives = 117/342 (34%), Gaps = 103/342 (30%)
Query: 100 CCPGYWGSRCHECPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPD 159
CC G++ SR P A+ HG C+ C C +RG C P +GP
Sbjct: 90 CCHGFYESRGFCVPLCAQECV--HGRCV----APNQCQCVPGWRGDDCSSECAPGMWGPQ 143
Query: 160 CQSVCSCVH--------GVCN-----------------------------HGPRGD---G 179
C CSC + GVC+ HG D G
Sbjct: 144 CDKPCSCGNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTG 203
Query: 180 SCLCFAGYTGPHCDQELPVCQE----LRCPQNTQC------SAEAPSCRCLPGYTQQGSE 229
+C C A TGP CD C + CP C SC C PG+ G+
Sbjct: 204 ACFCPAERTGPSCDVS---CSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGW--MGTI 258
Query: 230 CRAPNP-CWPSP-CSLLAQC---SVSPKGQAQCHCPENYHGD-----------GMVCLPK 273
C P P + P CS +C + + QC C Y GD G C
Sbjct: 259 CSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAET 318
Query: 274 DPCTDNLGGCPSN-STLCVYQKPGQAFCT---CRPGLVSINSNASAGCFAFCSPFSCDR- 328
C + P+N + LC + G CT C G ++ A P +CDR
Sbjct: 319 CDCAPDARCFPANGACLCEHGFTGDR-CTDRLCPDGFYGLSCQA---------PCTCDRE 368
Query: 329 -SATCQVTADGKTSCV-------CRESEVGD--GRACYGHLL 360
S +C +G+ SC+ C ES D G C H L
Sbjct: 369 HSLSCH-PMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCL 409
Score = 64.7 bits (156), Expect = 1e-09
Identities = 75/295 (25%), Positives = 96/295 (32%), Gaps = 72/295 (24%)
Query: 720 CCKGFFGPDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQ 779
CC GF+ GF P + C C P ++G C P G Q
Sbjct: 90 CCHGFYESR------GFCVPLCAQECVHGRCVAPNQCQCVPGWRGDDCSSECAPGMWGPQ 143
Query: 780 CQEDCGC-VHGLCDNRPGSGGVCQQG--------TCAPGFSGRFCNESMGDCGPTGLAQH 830
C + C C + CD + G C G C PG+ G C
Sbjct: 144 CDKPCSCGNNSSCDPKSGVCS-CPSGLQPPNCLQPCTPGYYGPACQ----------FRCQ 192
Query: 831 CHLHARCVSQEGVARC-----------RCLDGFEGDGFSCTPSNPCSH-----PDRGGCS 874
CH A C Q G C C G GF C ++ C + +G CS
Sbjct: 193 CH-GAPCDPQTGACFCPAERTGPSCDVSCSQG--TSGFFCPSTHSCQNGGVFQTPQGSCS 249
Query: 875 ENAECVPGSLGT-HHCTCHKGWSGDGRVCVAIDECELDMRGGCHTDALCSYVGPGQSRCT 933
C PG +GT C +G+ G C + R CH LC +C
Sbjct: 250 ----CPPGWMGTICSLPCPEGFHG--------PNCSQECR--CHNGGLCDRF---TGQCR 292
Query: 934 CKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQ-----RVCTCPPGFGGD 983
C G+ GD +C + C G G TC + C C GF GD
Sbjct: 293 CAPGYTGD--RCR--EECPVGRFGQDCAETCDCAPDARCFPANGACLCEHGFTGD 343
Score = 59.3 bits (142), Expect = 5e-08
Identities = 49/166 (29%), Positives = 65/166 (39%), Gaps = 20/166 (12%)
Query: 720 CCKGFFGPDCTQC--PGGFSNPCYGK--GNCSDGIQGNGACLCFPDYKGIACHICSNPNK 775
C GF GP C + PG + C N S NG C C + G C P
Sbjct: 597 CAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGH 656
Query: 776 HGEQCQEDCGCVH-GLCDNRPGS--------GGVCQQGTCAPGFSGRFCNESMGDCGPTG 826
GE C + C C H G C + GS G C +G C G G C++ CGP
Sbjct: 657 WGENCAQTCQCHHGGTCHPQDGSCICPLGWTGHHCLEG-CPLGTFGANCSQPC-QCGP-- 712
Query: 827 LAQHCHLH-ARCVSQEGVARCRCLDGFEGDGFSCTPSNPCSHPDRG 871
+ CH CV G + C G + + F+ P+ P ++ G
Sbjct: 713 -GEKCHPETGACVCPPGHSGAPCRIGIQ-EPFTVMPTTPVAYNSLG 756
Score = 58.2 bits (139), Expect = 1e-07
Identities = 37/113 (32%), Positives = 50/113 (44%), Gaps = 16/113 (14%)
Query: 1959 CCPGHYGSEC-QACPGGPSSPCSDRGVCMDGMSGSGQCLCRSGFAGTAC-ELCAPGAFGP 2016
C PGH+G C Q C C G C G C+C G+ G C E C G FG
Sbjct: 652 CPPGHWGENCAQTCQ------CHHGGTCHPQ---DGSCICPLGWTGHHCLEGCPLGTFGA 702
Query: 2017 HC-QACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEA 2068
+C Q C+C +C +G+C C G +G C + ++ +P P P A
Sbjct: 703 NCSQPCQCGPGEKCHPE---TGACVCPPGHSGAPCRIGIQ-EPFTVMPTTPVA 751
Score = 54.7 bits (130), Expect = 1e-06
Identities = 38/108 (35%), Positives = 47/108 (43%), Gaps = 14/108 (12%)
Query: 1320 CCPGFFGTLC-EPCPGGLGG-----VCSGH--GQCQDRFLGSGECHCHEGFHGTAC-EVC 1370
C G+ G C +PCP G G C H G C + G C C G+ G C E C
Sbjct: 639 CLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQ---DGSCICPLGWTGHHCLEGC 695
Query: 1371 ELGRYGPNCTGVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSP 1418
LG +G NC+ C C G ++ G+CVC G G C I P
Sbjct: 696 PLGTFGANCSQPCQCGPG--EKCHPETGACVCPPGHSGAPCRIGIQEP 741
Score = 53.1 bits (126), Expect = 3e-06
Identities = 61/231 (26%), Positives = 79/231 (34%), Gaps = 55/231 (23%)
Query: 1379 CTGVC--DCAHGLCQEGLQGDGSCVCNVGWQGLRCDQK----ITSPQC--PRKCDPNANC 1430
C +C +C HG C Q C C GW+G C + + PQC P C N++C
Sbjct: 101 CVPLCAQECVHGRCVAPNQ----CQCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNNSSC 156
Query: 1431 VQDSAGASTCACAAGYSGNGIFCSEVDPCAHGHGG-------------CSPHANCTKVAP 1477
S C+C +G + PC G+ G C P P
Sbjct: 157 DPKS---GVCSCPSGLQPPNC----LQPCTPGYYGPACQFRCQCHGAPCDPQTGAC-FCP 208
Query: 1478 GQRT---CTCQDGYMGDGELCQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDG 1534
+RT C G C +SC +GG Q SCSC G+ G
Sbjct: 209 AERTGPSCDVSCSQGTSGFFCPSTHSC--QNGGVF--------QTPQGSCSCPPGWMG-- 256
Query: 1535 IRTCELLDPCSKNNGGCSPYATCKSTGDGQR---TCTCDTAHTVGDGLTCR 1582
C L P + CS C + G R C C +T G CR
Sbjct: 257 -TICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGYT---GDRCR 303
Score = 47.4 bits (111), Expect = 2e-04
Identities = 68/293 (23%), Positives = 94/293 (32%), Gaps = 66/293 (22%)
Query: 2050 CEVQLELQPVCTPPCAPEAV---CRAGNSCECSLGYEGDGRVCTVADLCQDGHGG----- 2101
C E + C P CA E V C A N C+C G+ GD + C G G
Sbjct: 91 CHGFYESRGFCVPLCAQECVHGRCVAPNQCQCVPGWRGD----DCSSECAPGMWGPQCDK 146
Query: 2102 ---CSEHANCSQVGTMVTCTCLPDYEGDGWSCRARNPCTDGHRGGCSEHANCLSTGLNTR 2158
C +++C + C+C + PCT G+ G +
Sbjct: 147 PCSCGNNSSCDPKSGV--CSCPSGLQPP----NCLQPCTPGYYGPACQF----------- 189
Query: 2159 RCECHAGYVGDGLQCLEESEPPVDRCLGQPPPCHSDAMCTDLHFQEKRAGVFHLQATSGP 2218
RC+CH G C +P C P D+ + +G F S
Sbjct: 190 RCQCH------GAPC----DPQTGACF---CPAERTGPSCDVSCSQGTSGFFCPSTHSCQ 236
Query: 2219 YGLNFSEAEAACEAQGAVLASFPQLSAAQQLGFH--------LCLMGWLANGSTAHPVVF 2270
G F + +C + + L + GFH C G L + T
Sbjct: 237 NGGVFQTPQGSCSCPPGWMGTICSLPCPE--GFHGPNCSQECRCHNGGLCDRFTGQCRCA 294
Query: 2271 P-------VADCGNGRVGIVSLGARKNLSERWDAYCFRVQDVACRCRNGFVGD 2316
P +C GR G + DA CF AC C +GF GD
Sbjct: 295 PGYTGDRCREECPVGRFG---QDCAETCDCAPDARCFPANG-ACLCEHGFTGD 343
>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
Length = 1044
Score = 112 bits (280), Expect = 5e-24
Identities = 95/311 (30%), Positives = 116/311 (37%), Gaps = 75/311 (24%)
Query: 87 CRR--KCRKQVVQKACCPGYWGSRCHE-CPGGA-------ETPCNGHGTCLDGMDRNGTC 136
CR C + + C PGY G C E CP G+ PC GTC G C
Sbjct: 191 CRHGASCDPRAGECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTC---HHITGEC 247
Query: 137 VCQENFRGSACQECQDPNRFGPDCQSVCSCVH-GVCNHGPRGDGSCLCFAGYTGPHCDQE 195
C + G+ C + P FG +C C C H G C+H G C C AGY G C +E
Sbjct: 248 ACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDH---VTGQCHCTAGYMGDRCQEE 304
Query: 196 LP-------VCQELRCPQNTQCSAEAPSCRCLPGYTQQGSECR---------APNPCWPS 239
P Q C QCS +C C PGY +G C+ P P
Sbjct: 305 CPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGY--KGPRCQERLCPEGLHGPGCTLPC 362
Query: 240 PCSLLAQCSVSP-KGQAQCH-----------CPENYHGDGMVCLPKDPCT-DNLGGCPSN 286
PC S P G C CP Y+GDG + PCT N C S
Sbjct: 363 PCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGC----QLPCTCQNGADCHSI 418
Query: 287 STLCVYQKPGQAFCTCRPGLVS--INSNASAG-----CFAFCSPFSCDRSATCQVTADGK 339
+ CTC PG + + +AG C + C SC+ TC DG
Sbjct: 419 T----------GGCTCAPGFMGEVCAVSCAAGTYGPNCSSIC---SCNNGGTCS-PVDG- 463
Query: 340 TSCVCRESEVG 350
SC C+E G
Sbjct: 464 -SCTCKEGWQG 473
Score = 110 bits (275), Expect = 2e-23
Identities = 97/307 (31%), Positives = 118/307 (38%), Gaps = 63/307 (20%)
Query: 711 CNQTIMEQGCCKGFFGPDCTQ--CPGGFSNPCYGKGNCSDGIQGN---GACLCFPDYKGI 765
CN C GF G C + PG C C G + G CLC P Y G+
Sbjct: 154 CNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAGECLCAPGYTGV 213
Query: 766 ACHICSNPNKHGEQCQEDCGC--------VHGLCDNRPG-SGGVCQQGTCAPGFSGRFCN 816
C P HG C+ C C + G C PG +G VC Q C PG G+ C+
Sbjct: 214 YCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQ-PCPPGTFGQNCS 272
Query: 817 ESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGD-----------GFSCTPSNPC 865
+ DC CH +C G +C C G+ GD GF C S C
Sbjct: 273 Q---DC-------PCHHGGQCDHVTG--QCHCTAGYMGDRCQEECPFGSFGFQC--SQHC 318
Query: 866 SHPDRGGCSEN---AECVPGSLG--THHCTCHKGWSGDGRVCVAIDECELDMRGGCH--T 918
+ G CS EC PG G C +G G G C C+ D CH T
Sbjct: 319 DCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPG--CTLPCPCDADNTISCHPVT 376
Query: 919 DALCSYVGPGQSRC--TCKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTC 976
A G C +C +G+ GDG Q PC NG A C ++ GG CTC
Sbjct: 377 GACTCQPGWSGHHCNESCPVGYYGDGCQL----PCTCQNG-----ADCHSITGG---CTC 424
Query: 977 PPGFGGD 983
PGF G+
Sbjct: 425 APGFMGE 431
Score = 105 bits (261), Expect = 8e-22
Identities = 83/257 (32%), Positives = 105/257 (40%), Gaps = 42/257 (16%)
Query: 1320 CCPGFFGTLC-EPCPGGL-GGVCSGHGQCQ---DRFLGSGECHCHEGFHGTACEV-CELG 1373
C PG+ G C E CP G G C CQ D +G C C GF G C V C G
Sbjct: 381 CQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAG 440
Query: 1374 RYGPNCTGVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQD 1433
YGPNC+ +C C +G + DGSC C GWQGL C S C+ + C
Sbjct: 441 TYGPNCSSICSCNNGGTCSPV--DGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANG 498
Query: 1434 SAGA---STCACAAGYSGN-----------GIFCSEVDPCAHGHGGCSP---HANCTKVA 1476
+A + +C+C G+ G+ G+ CSE C+H GC P H C
Sbjct: 499 AACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHA-DGCDPVTGHCCCLAGW 557
Query: 1477 PGQR-TCTCQDGYMGDGELCQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGI 1535
G R TC G G C SC +GG P+ SC C G+ G
Sbjct: 558 TGIRCDSTCPPGRWGPN--CSV--SCSCENGG--------SCSPEDGSCECAPGFRGP-- 603
Query: 1536 RTCELLDPCSKNNGGCS 1552
C+ + P GC+
Sbjct: 604 -LCQRICPPGFYGHGCA 619
Score = 104 bits (259), Expect = 1e-21
Identities = 100/331 (30%), Positives = 124/331 (37%), Gaps = 106/331 (32%)
Query: 1320 CCPGFFGTLC-EPCPGGLGGV-------CSGHGQCQDRFLGSGECHCHEGFHGTAC-EVC 1370
C PG+ G +C +PCP G G C GQC +G+CHC G+ G C E C
Sbjct: 249 CPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHV---TGQCHCTAGYMGDRCQEEC 305
Query: 1371 ELGRYGPNCTGVCDCAHG------------------------LCQEGLQGDG-------- 1398
G +G C+ CDC +G LC EGL G G
Sbjct: 306 PFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCD 365
Query: 1399 ------------SCVCNVGWQGLRCDQKI------TSPQCPRKCDPNANCVQDSAGASTC 1440
+C C GW G C++ Q P C A+C + G C
Sbjct: 366 ADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGG---C 422
Query: 1441 ACAAGYSGNGIFCSEVDPCAHGHGG--CSPHANCTK---VAPGQRTCTCQDGYMG----- 1490
CA G+ G S CA G G CS +C +P +CTC++G+ G
Sbjct: 423 TCAPGFMGEVCAVS----CAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTL 478
Query: 1491 ------DGELCQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLDPC 1544
G C E SC +G A C P SCSC G+ GD TCEL PC
Sbjct: 479 PCPSGTWGLNCNE--SCTCANG-----AAC---SPIDGSCSCTPGWLGD---TCEL--PC 523
Query: 1545 SKNNGG--CSPYATCKSTGDGQRTCTCDTAH 1573
G CS + C S DG C T H
Sbjct: 524 PDGTFGLNCSEHCDC-SHADG---CDPVTGH 550
Score = 102 bits (254), Expect = 5e-21
Identities = 93/276 (33%), Positives = 114/276 (41%), Gaps = 45/276 (16%)
Query: 1947 HRNCVTTTWKPSCCPGHYGSECQA-CPGGPSSP-CSDRGVCMDGMSGS---GQCLCRSGF 2001
H CV+ C PG G +C + C P CS+R C +G + G C+C +GF
Sbjct: 109 HGRCVSPD-TCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPITGACVCAAGF 167
Query: 2002 AGTACE-LCAPGAFGPHCQ-ACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPV 2059
G CE LCAPG G CQ C+C CD +G C C G+TG CE +
Sbjct: 168 RGWRCEELCAPGTHGKGCQLPCQCRHGASCDP---RAGECLCAPGYTGVYCE------EL 218
Query: 2060 CTP-----PCAPEAVCRAGNSC-----ECSLGYEGDGRVCTVADLCQDGHGG--CSEHAN 2107
C P C C+ G +C EC+ G VC A C G G CS+
Sbjct: 219 CPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVC--AQPCPPGTFGQNCSQDCP 276
Query: 2108 CSQVGTM--VT--CTCLPDYEGDGWSCRARNPCTDGHRG-GCSEHANCLSTGL---NTRR 2159
C G VT C C Y GD R + C G G CS+H +C + G T
Sbjct: 277 CHHGGQCDHVTGQCHCTAGYMGD----RCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGA 332
Query: 2160 CECHAGYVGDGLQCLEESEPPVDRCLGQPPPCHSDA 2195
CEC GY G +C E P G PC DA
Sbjct: 333 CECEPGYKGP--RCQERLCPEGLHGPGCTLPCPCDA 366
Score = 101 bits (252), Expect = 8e-21
Identities = 103/365 (28%), Positives = 133/365 (36%), Gaps = 70/365 (19%)
Query: 1262 HSHAEALREKCVNCTRRFRCTQ-----------GFQLQDTPRKSCV---YRSGFSFSRGC 1307
H + +C + F+CT+ G + R C Y SG C
Sbjct: 44 HPFDQIYYTRCTDILNWFKCTRHRISYKTAYRRGLRTMYRRRSQCCPGYYESGDFCIPLC 103
Query: 1308 SYTCAK-KIQVPDCC---PGFFGTLCEP-CPGGLGGV-CSGHGQCQDRFLGS---GECHC 1358
+ C + PD C PG+ G C C G CS QCQ+ L + G C C
Sbjct: 104 TEECVHGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPITGACVC 163
Query: 1359 HEGFHGTACE-VCELGRYGPNCTGVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITS 1417
GF G CE +C G +G C C C HG + G+ C+C G+ G+ C++
Sbjct: 164 AAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAGE--CLCAPGYTGVYCEELCPP 221
Query: 1418 PQCPRKCDPNANCVQDSAG---ASTCACAAGYSGN-----------GIFCSEVDPCAHGH 1463
C+ C CAC G++G G CS+ PC HG
Sbjct: 222 GSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHG- 280
Query: 1464 GGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQE------INSCLIHHGGCHIHAECIPT 1517
C V GQ C C GYMGD CQE H CH +C PT
Sbjct: 281 ------GQCDHVT-GQ--CHCTAGYMGD--RCQEECPFGSFGFQCSQHCDCHNGGQCSPT 329
Query: 1518 GPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKSTGDGQRTCTCDTAHTVGD 1577
+C C GY G R E L P + GC+ C D T +C H V
Sbjct: 330 ---TGACECEPGYKGP--RCQERLCPEGLHGPGCTLPCPC----DADNTISC---HPVTG 377
Query: 1578 GLTCR 1582
TC+
Sbjct: 378 ACTCQ 382
Score = 100 bits (248), Expect = 2e-20
Identities = 113/403 (28%), Positives = 146/403 (36%), Gaps = 106/403 (26%)
Query: 1959 CCPGHYGSECQACPGGPSSPCSDRGVCMDGMS---GSGQCLCRSGFAGTAC-ELCAPGAF 2014
C PG +G CQ PC C G S +G+CLC G+ G C ELC PG+
Sbjct: 176 CAPGTHGKGCQL-------PCQ----CRHGASCDPRAGECLCAPGYTGVYCEELCPPGSH 224
Query: 2015 GPHCQ-ACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPVCTP-----PCAPEA 2068
G HC+ C C G C +G C C GWTG C QP C P C+ +
Sbjct: 225 GAHCELRCPCQNGGTCHH---ITGECACPPGWTGAVC-----AQP-CPPGTFGQNCSQDC 275
Query: 2069 VCRAGNSCE-------CSLGYEGDGRVCTVADLCQDGHGG--CSEHANCSQVG----TMV 2115
C G C+ C+ GY GD + C G G CS+H +C G T
Sbjct: 276 PCHHGGQCDHVTGQCHCTAGYMGD----RCQEECPFGSFGFQCSQHCDCHNGGQCSPTTG 331
Query: 2116 TCTCLPDYEGDGWSCRARNPCTDG-HRGGCSEHANC----------------LSTGLNTR 2158
C C P Y+G C+ R C +G H GC+ C G +
Sbjct: 332 ACECEPGYKGP--RCQER-LCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGH 388
Query: 2159 RC--ECHAGYVGDGLQCLEESEPPVDRCLGQPPPCHS---DAMCTDLHFQEKRAGVFHLQ 2213
C C GY GDG Q + D CHS C E V +
Sbjct: 389 HCNESCPVGYYGDGCQLPCTCQNGAD--------CHSITGGCTCAPGFMGE----VCAVS 436
Query: 2214 ATSGPYGLNFSEAEAACEAQGAVLASFPQLSAAQQLGFHLCLMGWLANGSTAHPVVFPVA 2273
+G YG N S +C G + + G C GW T
Sbjct: 437 CAAGTYGPNCSSI-CSCNNGG---------TCSPVDGSCTCKEGWQGLDCT--------L 478
Query: 2274 DCGNGRVGIVSLGARKNLSERWDAYCFRVQDVACRCRNGFVGD 2316
C +G G L ++ + A C + D +C C G++GD
Sbjct: 479 PCPSGTWG---LNCNESCTCANGAACSPI-DGSCSCTPGWLGD 517
Score = 99.8 bits (247), Expect = 3e-20
Identities = 93/322 (28%), Positives = 113/322 (35%), Gaps = 80/322 (24%)
Query: 100 CCPGYWGSRCHE-CPGGAETP-CNGHGTCLDGMDRN---GTCVCQENFRGSACQECQDPN 154
C PG+ G C C P C+ C +G N G CVC FRG C+E P
Sbjct: 120 CEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPG 179
Query: 155 RFGPDCQSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQELPVCQ-----ELRCP--QN 207
G CQ C C HG + PR G CLC GYTG +C++ P ELRCP
Sbjct: 180 THGKGCQLPCQCRHG-ASCDPRA-GECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNG 237
Query: 208 TQCSAEAPSCRCLPGYTQQGSECRAPNPCWPSPCSLLAQCSVSPKGQ-----AQCHCPEN 262
C C C PG+T G+ C P P + C GQ QCHC
Sbjct: 238 GTCHHITGECACPPGWT--GAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAG 295
Query: 263 YHGD-----------------------GMVCLP-----------KDP------CTDNLGG 282
Y GD G C P K P C + L G
Sbjct: 296 YMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHG 355
Query: 283 ------CPSNSTLCVYQKPGQAFCTCRPGLVSINSNASA-------GCFAFCSPFSCDRS 329
CP ++ + P CTC+PG + N S GC P +C
Sbjct: 356 PGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQL---PCTCQNG 412
Query: 330 ATCQVTADGKTSCVCRESEVGD 351
A C G C C +G+
Sbjct: 413 ADCHSITGG---CTCAPGFMGE 431
Score = 92.4 bits (228), Expect = 5e-18
Identities = 91/311 (29%), Positives = 119/311 (38%), Gaps = 59/311 (18%)
Query: 1257 SSRCLHSHAEALREKCVNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRGCSY----TCA 1312
S C SHA+ C T C G+ R G + S CS +C+
Sbjct: 533 SEHCDCSHADG----CDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCS 588
Query: 1313 KKIQVPDCCPGFFGTLCEP-CPGGLGGVCSGHGQCQDRFLG----------SGECHCHEG 1361
+ +C PGF G LC+ CP G GHG Q L SG C C G
Sbjct: 589 PEDGSCECAPGFRGPLCQRICPPGF----YGHGCAQPCPLCVHSSRPCHHISGICECLPG 644
Query: 1362 FHGTAC-EVCELGRYGPNCTGVCDCA-HGLCQEGLQGDGSCVCNVGWQGLRCDQK----I 1415
F G C +VC G +G +C +C CA +G C DGSC C GW G C Q
Sbjct: 645 FSGALCNQVCAGGYFGQDCAQLCSCANNGTCS---PIDGSCQCFPGWIGKDCSQACPPGF 701
Query: 1416 TSPQCPRKCDPNANCVQDSAGASTCACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKV 1475
P C C + N SA C C G++ G+FC++ P A C C
Sbjct: 702 WGPACFHACSCH-NGASCSAEDGACHCTPGWT--GLFCTQRCPAAFFGKDCGRVCQCQNG 758
Query: 1476 APGQR---TCTCQDGYMGD-----------GELCQEINSCLIHHGGCHIHAECIPTGPQQ 1521
A CTC+ G+ G G CQ++ C+ + H+ TG
Sbjct: 759 ASCDHISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQLCECMNNSTCDHV------TG--- 809
Query: 1522 VSCSCREGYSG 1532
+C C G+ G
Sbjct: 810 -TCYCSPGFKG 819
Score = 91.7 bits (226), Expect = 9e-18
Identities = 82/260 (31%), Positives = 114/260 (43%), Gaps = 59/260 (22%)
Query: 1950 CVTTTWKPSCCPGHYGSEC-QACPGGP-------SSPCSDRGVCMDGMSGSGQCLCRSGF 2001
C T + +C PG G+ C Q CP G PC G C D ++G QC C +G+
Sbjct: 240 CHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQC-DHVTG--QCHCTAGY 296
Query: 2002 AGTAC-ELCAPGAFGPHC-QACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQ-- 2057
G C E C G+FG C Q C C G+C +G+C C+ G+ GPRC+ +L +
Sbjct: 297 MGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPT---TGACECEPGYKGPRCQERLCPEGL 353
Query: 2058 --PVCTPPCAPEA-------------VCR---AGNSC--ECSLGYEGDGRVCTVADLCQD 2097
P CT PC +A C+ +G+ C C +GY GDG C + CQ+
Sbjct: 354 HGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDG--CQLPCTCQN 411
Query: 2098 GHGGCSEHANCSQVGTMVTCTCLPDYEGDGWSCRARNPCTDGHRG-GCSEHANCLSTGLN 2156
G A+C + CTC P + G+ + C G G CS +C + G
Sbjct: 412 G-------ADCHSI--TGGCTCAPGFMGEVCAV----SCAAGTYGPNCSSICSCNNGGTC 458
Query: 2157 T---RRCECHAGYVGDGLQC 2173
+ C C G+ GL C
Sbjct: 459 SPVDGSCTCKEGW--QGLDC 476
Score = 90.9 bits (224), Expect = 1e-17
Identities = 84/295 (28%), Positives = 115/295 (38%), Gaps = 46/295 (15%)
Query: 54 TCPSGWLRELPD-QITQDCRYEVQLGGSMVSMSG---CRRKCRKQVVQKACCPGYWGSRC 109
TCP G R P+ ++ C + GGS G C R + Q+ C PG++G C
Sbjct: 565 TCPPG--RWGPNCSVSCSC----ENGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGC 618
Query: 110 HE-CP--GGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSC 166
+ CP + PC+ +G C C F G+ C + FG DC +CSC
Sbjct: 619 AQPCPLCVHSSRPCH---------HISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSC 669
Query: 167 V-HGVCNHGPRGDGSCLCFAGYTGPHCDQEL------PVC-QELRCPQNTQCSAEAPSCR 218
+G C+ DGSC CF G+ G C Q P C C CSAE +C
Sbjct: 670 ANNGTCS---PIDGSCQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGACH 726
Query: 219 CLPGYTQQGSECRAPNPCWPSPCSLLAQCSVSPKG---QAQCHCPENYHGD--GMVCLPK 273
C PG+T R P + C + QC +C C + G C P
Sbjct: 727 CTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISGKCTCRTGFTGQHCEQRCAPG 786
Query: 274 D---PCTDNLGGCPSNSTLCVYQKPGQAFCTCRPGLVSINSNASAGCFAFCSPFS 325
C L C +NST C + C C PG I + +A +P++
Sbjct: 787 TFGYGC-QQLCECMNNST-CDHV---TGTCYCSPGFKGIRCDQAALMMEELNPYT 836
Score = 90.1 bits (222), Expect = 2e-17
Identities = 87/294 (29%), Positives = 111/294 (37%), Gaps = 51/294 (17%)
Query: 710 YCNQTIMEQGCCKGFFGPDCT-QCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACH 768
Y E+ C +G GP CT CP N +C GAC C P + G C+
Sbjct: 339 YKGPRCQERLCPEGLHGPGCTLPCPCDADNTI----SCH---PVTGACTCQPGWSGHHCN 391
Query: 769 ICSNPNKHGEQCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNES--MGDCGPT- 825
+G+ CQ C C +G D +GG TCAPGF G C S G GP
Sbjct: 392 ESCPVGYYGDGCQLPCTCQNG-ADCHSITGGC----TCAPGFMGEVCAVSCAAGTYGPNC 446
Query: 826 GLAQHCHLHARCVSQEGVARCRCLDGFEGDGFSCTPSNPCSHPDRG-GCSENAECVPGSL 884
C+ C +G C C +G++ G CT PC G C+E+ C G+
Sbjct: 447 SSICSCNNGGTCSPVDG--SCTCKEGWQ--GLDCT--LPCPSGTWGLNCNESCTCANGAA 500
Query: 885 GT---HHCTCHKGWSGDGRVCVAIDECELDMRGG-----CHTDALCSYV---GPGQSRCT 933
+ C+C GW G D CEL G C CS+ P C
Sbjct: 501 CSPIDGSCSCTPGWLG--------DTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCC 552
Query: 934 CKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRAVGGG-----QRVCTCPPGFGG 982
C G+ G +C C G G + +C GG C C PGF G
Sbjct: 553 CLAGWT--GIRCD--STCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRG 602
Score = 88.6 bits (218), Expect = 7e-17
Identities = 99/352 (28%), Positives = 122/352 (34%), Gaps = 95/352 (26%)
Query: 711 CNQTIMEQGCCKGFFGPDCTQ-CP-GGFSNPCYGKGNCSDGIQGN---GACLCFPDYKGI 765
C+ + C G+ G C + CP G F C +C +G Q + GAC C P YKG
Sbjct: 283 CDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGP 342
Query: 766 ACH--ICSNPNKHGEQCQEDCGC----------VHGLCDNRPGSGG-------------- 799
C +C HG C C C V G C +PG G
Sbjct: 343 RCQERLCPE-GLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGD 401
Query: 800 ------VCQQG----------TCAPGFSGRFCNESM--GDCGPT-GLAQHCHLHARCVSQ 840
CQ G TCAPGF G C S G GP C+ C
Sbjct: 402 GCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPV 461
Query: 841 EGVARCRCLDGFEGDGFSCTPSNPCSHPDRG-GCSENAECVPGSLGTH---HCTCHKGWS 896
+G C C +G++G CT PC G C+E+ C G+ + C+C GW
Sbjct: 462 DG--SCTCKEGWQG--LDCTL--PCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWL 515
Query: 897 GDGRVCVAIDECELDMRGG-----CHTDALCSYVG---PGQSRCTCKLGFAGD------- 941
GD CEL G C CS+ P C C G+ G
Sbjct: 516 GD--------TCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCP 567
Query: 942 ----GYQCSPIDPCRAGNGGCHGLATCRAVGGG-----QRVCTCPPGFGGDG 984
G CS C G +C G QR+C PPGF G G
Sbjct: 568 PGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPLCQRIC--PPGFYGHG 617
Score = 86.7 bits (213), Expect = 3e-16
Identities = 84/323 (26%), Positives = 109/323 (33%), Gaps = 85/323 (26%)
Query: 100 CCPGYWGSRCHE-CP-----GGAETPCNGHGTCLDGMDRN---GTCVCQENFRGSACQEC 150
C PG+ G C+E CP G + PC TC +G D + G C C F G C
Sbjct: 381 CQPGWSGHHCNESCPVGYYGDGCQLPC----TCQNGADCHSITGGCTCAPGFMGEVCAVS 436
Query: 151 QDPNRFGPDCQSVCSCVHG----------VCNHGPRG----------------------- 177
+GP+C S+CSC +G C G +G
Sbjct: 437 CAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCA 496
Query: 178 --------DGSCLCFAGYTGPHCDQELP-------VCQELRCPQNTQCSAEAPSCRCLPG 222
DGSC C G+ G C+ P + C C C CL G
Sbjct: 497 NGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAG 556
Query: 223 YTQQGSECRAPNPCWPSPCSLLAQC----SVSPKGQAQCHCPENYHGDGMVCLPKDPCTD 278
+T + P W CS+ C S SP+ C C + G +C P
Sbjct: 557 WTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPE-DGSCECAPGFRGP--LCQRICPPGF 613
Query: 279 NLGGCPSNSTLCVYQKPG----QAFCTCRPGLV-SINSNASAG------CFAFCSPFSCD 327
GC LCV+ C C PG ++ + AG C C SC
Sbjct: 614 YGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLC---SCA 670
Query: 328 RSATCQVTADGKTSCVCRESEVG 350
+ TC DG SC C +G
Sbjct: 671 NNGTCS-PIDG--SCQCFPGWIG 690
Score = 85.5 bits (210), Expect = 6e-16
Identities = 73/280 (26%), Positives = 97/280 (34%), Gaps = 44/280 (15%)
Query: 55 CPSGWLREL------PDQITQDCRYEVQL--GGSMVSMSGCRRKCRKQVVQKACCPGYWG 106
CP GW + P Q+C + GG ++G Q C GY G
Sbjct: 249 CPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTG----------QCHCTAGYMG 298
Query: 107 SRC-HECP-GGAETPCNGHGTCLDG---MDRNGTCVCQENFRGSACQECQDPNRF-GPDC 160
RC ECP G C+ H C +G G C C+ ++G CQE P GP C
Sbjct: 299 DRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGC 358
Query: 161 QSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQELPV------CQ-ELRCPQNTQCSAE 213
C C G+C C G++G HC++ PV CQ C C +
Sbjct: 359 TLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSI 418
Query: 214 APSCRCLPGYTQQGSECRAPNPCWPSPCSLLAQC----SVSPKGQAQCHCPENYHGDGMV 269
C C PG+ + + CS + C + SP C C E + G
Sbjct: 419 TGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPV-DGSCTCKEGWQGLDCT 477
Query: 270 CLPKDPCTDNLGGCPSNSTLCVYQ----KPGQAFCTCRPG 305
PC G N + P C+C PG
Sbjct: 478 L----PCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPG 513
Score = 82.4 bits (202), Expect = 5e-15
Identities = 83/304 (27%), Positives = 102/304 (33%), Gaps = 78/304 (25%)
Query: 720 CCKGFFGPDCTQ-CPGGFSNPCYGKG-----NCSDGIQGN---GACLCFPDYKGIACHIC 770
C G+ G C + CP G+ YG G C +G + G C C P + G C +
Sbjct: 381 CQPGWSGHHCNESCPVGY----YGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVS 436
Query: 771 SNPNKHGEQCQEDCGC--------VHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDC 822
+G C C C V G C + G G+ C G G CNES
Sbjct: 437 CAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESC--- 493
Query: 823 GPTGLAQHCHLHARCVSQEGVARCRCLDGFEGD-----------GFSCTPSNPCSHPDRG 871
C A C +G C C G+ GD G +C+ CSH D
Sbjct: 494 -------TCANGAACSPIDG--SCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHAD-- 542
Query: 872 GCSENAECVPGSLGTHHCTCHKGWSGDGRVCVAIDECELDMRGGCHTDALCS-----YVG 926
GC T HC C GW+G + D R G + CS
Sbjct: 543 GCDP---------VTGHCCCLAGWTG-----IRCDSTCPPGRWGPNCSVSCSCENGGSCS 588
Query: 927 PGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGC--------HGLATCRAVGGGQRVCTCPP 978
P C C GF G C I P GC H C + G +C C P
Sbjct: 589 PEDGSCECAPGFRGP--LCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISG---ICECLP 643
Query: 979 GFGG 982
GF G
Sbjct: 644 GFSG 647
Score = 79.3 bits (194), Expect = 4e-14
Identities = 101/388 (26%), Positives = 135/388 (34%), Gaps = 89/388 (22%)
Query: 1949 NCVTTTWKPSCCPGHYGSECQ-ACPGGPSSP-CSDRGVCMDGMSGS---GQCLCRSGFAG 2003
+C + T +C PG G C +C G P CS C +G + S G C C+ G+ G
Sbjct: 414 DCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQG 473
Query: 2004 TACEL-CAPGAFGPHC-QACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPVCT 2061
C L C G +G +C ++C C C GSC C GW G CE+
Sbjct: 474 LDCTLPCPSGTWGLNCNESCTCANGAACSPI---DGSCSCTPGWLGDTCEL--------- 521
Query: 2062 PPCAPEAVCRAGNSCECSLGYEGDGRVCTVADLCQDGHGGCSEHANCSQVGTMVTC--TC 2119
PC P+ S C C+ AD C G C C T + C TC
Sbjct: 522 -PC-PDGTFGLNCSEHCD---------CSHADGCDPVTGHCC----CLAGWTGIRCDSTC 566
Query: 2120 LPDYEGDGWSCRARNPCTDGHRGGCS-EHANC-LSTGLNTRRCE--CHAGYVGDGLQCLE 2175
P G +C C +G G CS E +C + G C+ C G+ G G C +
Sbjct: 567 PPGRWGP--NCSVSCSCENG--GSCSPEDGSCECAPGFRGPLCQRICPPGFYGHG--CAQ 620
Query: 2176 ESEPPVDRCLGQPPPCHS-DAMCTDLHFQEKRAGVFHLQATSGPYGLNFSEAEAACEAQG 2234
P C+ PCH +C L +G Q +G Y +C G
Sbjct: 621 ----PCPLCVHSSRPCHHISGICECL---PGFSGALCNQVCAGGYFGQDCAQLCSCANNG 673
Query: 2235 AVLASFPQLSAAQQLGFHLCLMGWLANGSTA-------HPVVFPVADCGNGRVGIVSLGA 2287
+ + G C GW+ + P F C NG
Sbjct: 674 ---------TCSPIDGSCQCFPGWIGKDCSQACPPGFWGPACFHACSCHNG--------- 715
Query: 2288 RKNLSERWDAYCFRVQDVACRCRNGFVG 2315
A C +D AC C G+ G
Sbjct: 716 ---------ASC-SAEDGACHCTPGWTG 733
Score = 76.6 bits (187), Expect = 3e-13
Identities = 78/286 (27%), Positives = 108/286 (37%), Gaps = 72/286 (25%)
Query: 707 CASYCNQTIMEQGCCKGFFGPDCTQ-CP--GGFSNPCYGKGNCSDGIQGNGACLCFPDYK 763
CA + ++ C GF+G C Q CP S PC+ +G C C P +
Sbjct: 596 CAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCH---------HISGICECLPGFS 646
Query: 764 GIACHICSNPNKHGEQCQEDCGCV-HGLCDNRPGSGGVCQQGTCAPGFSGRFCNESM--G 820
G C+ G+ C + C C +G C GS CQ C PG+ G+ C+++ G
Sbjct: 647 GALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGS---CQ---CFPGWIGKDCSQACPPG 700
Query: 821 DCGPTGL-AQHCHLHARCVSQEGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAEC 879
GP A CH A C +++G C C G+ G CT P + + C +C
Sbjct: 701 FWGPACFHACSCHNGASCSAEDGA--CHCTPGW--TGLFCTQRCPAAFFGK-DCGRVCQC 755
Query: 880 VPGSLGTH---HCTCHKGWSGDGRVCVAIDECELDMRGGCHTDALCSYVGPGQSRCTCKL 936
G+ H CTC G++G H + C+ PG
Sbjct: 756 QNGASCDHISGKCTCRTGFTGQ------------------HCEQRCA---PGTF------ 788
Query: 937 GFAGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGFGG 982
GY C + C C +TC V G C C PGF G
Sbjct: 789 -----GYGCQQL--CE-----CMNNSTCDHVTG---TCYCSPGFKG 819
Score = 75.9 bits (185), Expect = 5e-13
Identities = 48/141 (34%), Positives = 63/141 (44%), Gaps = 31/141 (21%)
Query: 1939 PQGLGRGCHRNCVTTTWKPSC---CPGHYGSECQA-------CPGGPSSPCSDRGV---- 1984
P +G+ C + C W P+C C H G+ C A PG C+ R
Sbjct: 686 PGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFF 745
Query: 1985 ---------CMDGMSG---SGQCLCRSGFAGTACE-LCAPGAFGPHC-QACRCTVHGRCD 2030
C +G S SG+C CR+GF G CE CAPG FG C Q C C + CD
Sbjct: 746 GKDCGRVCQCQNGASCDHISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQLCECMNNSTCD 805
Query: 2031 EGLGGSGSCFCDEGWTGPRCE 2051
+G+C+C G+ G RC+
Sbjct: 806 H---VTGTCYCSPGFKGIRCD 823
Score = 63.9 bits (154), Expect = 2e-09
Identities = 37/110 (33%), Positives = 55/110 (50%), Gaps = 8/110 (7%)
Query: 1310 TCAKKIQVPDCCPGFFGTLC-EPCPGGLGGV-CSGHGQCQDRFLG---SGECHCHEGFHG 1364
+C+ + C PG+ G C + CP G C QCQ+ SG+C C GF G
Sbjct: 717 SCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISGKCTCRTGFTG 776
Query: 1365 TACEV-CELGRYGPNCTGVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQ 1413
CE C G +G C +C+C + + + G +C C+ G++G+RCDQ
Sbjct: 777 QHCEQRCAPGTFGYGCQQLCECMNNSTCDHVTG--TCYCSPGFKGIRCDQ 824
Score = 58.2 bits (139), Expect = 1e-07
Identities = 61/218 (27%), Positives = 76/218 (34%), Gaps = 51/218 (23%)
Query: 2009 CAPGAF--GPHCQACRCT---VHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQ---PVC 2060
C PG + G C CT VHGRC +C C+ GW GP C + P C
Sbjct: 88 CCPGYYESGDFCIPL-CTEECVHGRCVS----PDTCHCEPGWGGPDCSSGCDSDHWGPHC 142
Query: 2061 TPPCAPE--AVCR-AGNSCECSLGYEGDGRVCTVADLCQDG-HG-GCSEHANCSQVGT-- 2113
+ C + A+C +C C+ G+ G +LC G HG GC C +
Sbjct: 143 SNRCQCQNGALCNPITGACVCAAGFRG----WRCEELCAPGTHGKGCQLPCQCRHGASCD 198
Query: 2114 --MVTCTCLPDYEG-----------DGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRC 2160
C C P Y G G C R PC GG H T C
Sbjct: 199 PRAGECLCAPGYTGVYCEELCPPGSHGAHCELRCPC---QNGGTCHHI--------TGEC 247
Query: 2161 ECHAGYVGDGLQCLEESEP-PVDRCLGQPPPCHSDAMC 2197
C G+ G C + P + Q PCH C
Sbjct: 248 ACPPGWT--GAVCAQPCPPGTFGQNCSQDCPCHHGGQC 283
Score = 51.6 bits (122), Expect = 1e-05
Identities = 47/168 (27%), Positives = 62/168 (36%), Gaps = 27/168 (16%)
Query: 669 CQALNTSTCPPNSVKLDIFP----KECVYIHDPTGLNVLKKGCASYCN-----QTIMEQG 719
C N TC P FP K+C P C C+ E G
Sbjct: 667 CSCANNGTCSPIDGSCQCFPGWIGKDCSQACPP---GFWGPACFHACSCHNGASCSAEDG 723
Query: 720 CCK---GFFGPDCTQ-CPGGF-SNPCYGKGNCSDGIQGN---GACLCFPDYKGIACHICS 771
C G+ G CTQ CP F C C +G + G C C + G C
Sbjct: 724 ACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISGKCTCRTGFTGQHCEQRC 783
Query: 772 NPNKHGEQCQEDCGCVHG-LCDNRPGSGGVCQQGTCAPGFSGRFCNES 818
P G CQ+ C C++ CD+ G+ C C+PGF G C+++
Sbjct: 784 APGTFGYGCQQLCECMNNSTCDHVTGT---CY---CSPGFKGIRCDQA 825
Score = 34.3 bits (77), Expect = 1.6
Identities = 28/100 (28%), Positives = 38/100 (38%), Gaps = 21/100 (21%)
Query: 1274 NCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKKIQVPDCCPGFFGTLCEP-C 1332
+C R +C G K C R+GF+ + C CA PG FG C+ C
Sbjct: 748 DCGRVCQCQNGASCDHISGK-CTCRTGFT-GQHCEQRCA---------PGTFGYGCQQLC 796
Query: 1333 PGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCEL 1372
C + C +G C+C GF G C+ L
Sbjct: 797 E------CMNNSTCDHV---TGTCYCSPGFKGIRCDQAAL 827
Score = 32.0 bits (71), Expect = 8.1
Identities = 22/77 (28%), Positives = 30/77 (38%), Gaps = 9/77 (11%)
Query: 1943 GRGCH----RNCVTTTWKPSCCPGHYGSECQ--ACPGGPSSPCSDRGVCMDGMSG---SG 1993
GR C +C + K +C G G C+ PG C CM+ + +G
Sbjct: 750 GRVCQCQNGASCDHISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQLCECMNNSTCDHVTG 809
Query: 1994 QCLCRSGFAGTACELCA 2010
C C GF G C+ A
Sbjct: 810 TCYCSPGFKGIRCDQAA 826
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 108 bits (269), Expect = 9e-23
Identities = 92/293 (31%), Positives = 116/293 (39%), Gaps = 51/293 (17%)
Query: 720 CCKGFFGPDCTQCPGGFS-NPCYGKGNCSDGIQGNGACLCFPDYKGIACHI----C-SNP 773
C +GF G C + S +PC+ G C DGI + +C C P Y G C C S P
Sbjct: 533 CAEGFEGTLCDRNVDDCSPDPCH-HGRCVDGI-ASFSCACAPGYTGTRCESQVDECRSQP 590
Query: 774 NKHGEQCQED-----CGCVHGL-----------CDNRPGSGGVCQQG------TCAPGFS 811
+HG +C + C C G C + P + GVC+ G C PGF+
Sbjct: 591 CRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFT 650
Query: 812 GRFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGDGFSCTPSNPCSH-PDR 870
G CN + +C + C CV E RC C G PS+PC+H P
Sbjct: 651 GPLCNVEINECA----SSPCGEGGSCVDGENGFRCLCPPG-SLPPLCLPPSHPCAHEPCS 705
Query: 871 GGCSENAECVPGSLGTHHCTCHKGWSGDG-RVCVAIDECELDMRGGCHTDALCSYVGPGQ 929
G +A G C C GWSG +A D CE C CS G G
Sbjct: 706 HGICYDAP------GGFRCVCEPGWSGPRCSQSLARDACESQ---PCRAGGTCSSDGMG- 755
Query: 930 SRCTCKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGFGG 982
CTC G G QC + PC C C + G VC+CP G+ G
Sbjct: 756 FHCTCPPGV--QGRQCELLSPCTP--NPCEHGGRCESAPGQLPVCSCPQGWQG 804
Score = 107 bits (268), Expect = 1e-22
Identities = 87/294 (29%), Positives = 110/294 (37%), Gaps = 47/294 (15%)
Query: 720 CCKGFFGPDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHI------CSNP 773
C +GF GPDC+ S+PC CS G G C C P Y+G +C P
Sbjct: 108 CPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEP 167
Query: 774 NKHGEQCQED-----CGCVHG----LCDNRP--------GSGGVCQQG-------TCAPG 809
+HG C C C G LC+N +GG C+Q C PG
Sbjct: 168 CRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPG 227
Query: 810 FSGRFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGDGFSCTPSNPCSHPD 869
F G+ C ++ DC C CV C+C E G CT
Sbjct: 228 FEGQNCEVNVDDCP----GHRCLNGGTCVDGVNTYNCQCPP--EWTGQFCTEDVDECQLQ 281
Query: 870 RGGCSENAECVPGSLGTHHCTCHKGWSGDGRVCVAIDECELDMRGGCHTDALCSYVGPGQ 929
C C +LG H C C GW+G+ ID+C + C A C +
Sbjct: 282 PNACHNGGTCF-NTLGGHSCVCVNGWTGES-CSQNIDDCATAV---CFHGATC-HDRVAS 335
Query: 930 SRCTCKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRAVG-GGQRVCTCPPGFGG 982
C C +G G C D C + CH A C G+ +CTCPPGF G
Sbjct: 336 FYCACPMGKTG--LLCHLDDACVSNP--CHEDAICDTNPVNGRAICTCPPGFTG 385
Score = 103 bits (256), Expect = 3e-21
Identities = 80/259 (30%), Positives = 107/259 (41%), Gaps = 42/259 (16%)
Query: 100 CCPGYWGSRCH----ECPGGAETPCNGHGTCLDGMDRNG-TCVCQENFRGSACQECQDPN 154
C PG+ G C+ EC A +PC G+C+DG NG C+C GS C P+
Sbjct: 645 CQPGFTGPLCNVEINEC---ASSPCGEGGSCVDG--ENGFRCLCPP---GSLPPLCLPPS 696
Query: 155 RFGPDCQSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQELP--VCQELRCPQNTQCSA 212
P CS HG+C P G C+C G++GP C Q L C+ C CS+
Sbjct: 697 H--PCAHEPCS--HGICYDAP-GGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSS 751
Query: 213 EAPS--CRCLPGYTQQGSECRAPNPCWPSPCSLLAQCSVSPKGQAQCHCPENYHG----- 265
+ C C PG QG +C +PC P+PC +C +P C CP+ + G
Sbjct: 752 DGMGFHCTCPPGV--QGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQ 809
Query: 266 DGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPGLVSINSNASAGCFAFCSPFS 325
D C PC + G C + + G CTC G + + C P
Sbjct: 810 DVDECAGPAPCGPH-GICTNLA--------GSFSCTCHGGYTGPSCDQDIN---DCDPNP 857
Query: 326 CDRSATCQVTADGKTSCVC 344
C +CQ G SC C
Sbjct: 858 CLNGGSCQ-DGVGSFSCSC 875
Score = 101 bits (251), Expect = 1e-20
Identities = 88/297 (29%), Positives = 112/297 (37%), Gaps = 45/297 (15%)
Query: 1919 PPLHSLGLRSVWVHPSLWGRPQGLGRGCHRNCVTTTWKPS------CCPGHYGSECQACP 1972
PP+ +L L + P P G C N T PS C PG G CQ
Sbjct: 22 PPVRALPLLLLLAGPGAAAPPCLDGSPC-ANGGRCTQLPSREAACLCPPGWVGERCQLED 80
Query: 1973 GGPSSPCSDRGVCMDG-MSGSGQ--CLCRSGFAGTACELCAPGAFGPHCQACRCTVHGRC 2029
S PC+ RGVC ++G+ + C C GF G C L P C + C RC
Sbjct: 81 PCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDP------CLSSPCAHGARC 134
Query: 2030 DEGLGGSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEAVC---RAGNSCECSLGYEGDG 2086
G G C C G+ G C ++ V PC C C+C GY G
Sbjct: 135 SVGPDGRFLCSCPPGYQGRSCRSDVDECRV-GEPCRHGGTCLNTPGSFRCQCPAGYTG-- 191
Query: 2087 RVCTVADLCQD-----GHGGCSEHANCSQVGTMV-TCTCLPDYEGDGWSCRARNPCTDGH 2140
LC++ C C Q G + C CLP +EG +C GH
Sbjct: 192 ------PLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQ--NCEVNVDDCPGH 243
Query: 2141 RGGCSEHANCLSTGLNTRRCECHAGYVGDGLQCLEESEPPVDRCLGQPPPCHSDAMC 2197
R C C+ G+NT C+C + G C E+ VD C QP CH+ C
Sbjct: 244 R--CLNGGTCVD-GVNTYNCQCPPEWTGQ--FCTED----VDECQLQPNACHNGGTC 291
Score = 101 bits (251), Expect = 1e-20
Identities = 84/284 (29%), Positives = 105/284 (36%), Gaps = 63/284 (22%)
Query: 1959 CCPGHYGSECQ---ACPGGPSSPCSDRGVCM-DGMSGSGQCLCRSGFAGTACELCAPGAF 2014
C PG G C A S PC G C DGM C C G G CEL +P
Sbjct: 720 CEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGF--HCTCPPGVQGRQCELLSP--- 774
Query: 2015 GPHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEAVCR--A 2072
C C GRC+ G C C +GW GPRC+ ++ + PC P +C A
Sbjct: 775 ---CTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVD-ECAGPAPCGPHGICTNLA 830
Query: 2073 GN-SCECSLGYEG----------DGRVCTVADLCQDGHGG-------------CSEHAN- 2107
G+ SC C GY G D C CQDG G C+ +
Sbjct: 831 GSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDE 890
Query: 2108 ----------CSQVGTMVTCTCLPDYEGDGWSCRARNPCTDGHRGGCSEHANCLSTGLNT 2157
C+ TCTC P Y G+ C P D C C+ G+N+
Sbjct: 891 CLSNPCGPGTCTDHVASFTCTCPPGY--GGFHCEQDLP--DCSPSSCFNGGTCVD-GVNS 945
Query: 2158 RRCECHAGYVGDGLQCLEESEPPVDRCLGQPPPCHSDAMCTDLH 2201
C C GY G C E++P + R PC +C+ H
Sbjct: 946 FSCLCRPGYT--GAHCQHEADPCLSR------PCLHGGVCSAAH 981
Score = 98.2 bits (243), Expect = 9e-20
Identities = 96/334 (28%), Positives = 126/334 (37%), Gaps = 62/334 (18%)
Query: 664 GSCVDCQALNTSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKGCASYCNQTIMEQGCCKG 723
GSCVD + CPP S+ P H+P + + C G
Sbjct: 670 GSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGF------RCVCEPG 723
Query: 724 FFGPDCTQC---PGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICS----NPNKH 776
+ GP C+Q S PC G CS G C C P +G C + S NP +H
Sbjct: 724 WSGPRCSQSLARDACESQPCRAGGTCSSDGMG-FHCTCPPGVQGRQCELLSPCTPNPCEH 782
Query: 777 GEQCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDC-GPTGLAQHCHLHA 835
G G C++ PG VC +C G+ G C + + +C GP C H
Sbjct: 783 G-----------GRCESAPGQLPVC---SCPQGWQGPRCQQDVDECAGPA----PCGPHG 824
Query: 836 RCVSQEGVARCRCLDGFEGDGFSCTPS-NPCSHPDRGGCSENAECVPGSLGTHHCTCHKG 894
C + G C C G+ G SC N C D C C G +G+ C+C G
Sbjct: 825 ICTNLAGSFSCTCHGGYTGP--SCDQDINDC---DPNPCLNGGSCQDG-VGSFSCSCLPG 878
Query: 895 WSGDGRVCVAIDECELDMRG-GCHTDALCSYVGPGQSRCTCKLGFAG-----DGYQCSPI 948
++G R +DEC + G G TD + S+ CTC G+ G D CSP
Sbjct: 879 FAGP-RCARDVDECLSNPCGPGTCTDHVASFT------CTCPPGYGGFHCEQDLPDCSP- 930
Query: 949 DPCRAGNGGCHGLATCRAVGGGQRVCTCPPGFGG 982
C TC G C C PG+ G
Sbjct: 931 -------SSCFNGGTC-VDGVNSFSCLCRPGYTG 956
Score = 95.5 bits (236), Expect = 6e-19
Identities = 78/301 (25%), Positives = 106/301 (35%), Gaps = 27/301 (8%)
Query: 55 CPSGWLRELPDQITQDCRYEVQLGGSMVSMSGCRRKCRKQVVQKACCPGYWGSRCH---- 110
CP+G+ L + C G SG AC PG+ G C
Sbjct: 185 CPAGYTGPLCENPAVPCAPSPCRNGGTCRQSG------DLTYDCACLPGFEGQNCEVNVD 238
Query: 111 ECPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHGV 170
+CPG C GTC+DG++ C C + G C E D + P+ +C +G
Sbjct: 239 DCPGHR---CLNGGTCVDGVNTYN-CQCPPEWTGQFCTEDVDECQLQPN-----ACHNGG 289
Query: 171 CNHGPRGDGSCLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQGSEC 230
G SC+C G+TG C Q + C C C S C + G C
Sbjct: 290 TCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLC 349
Query: 231 RAPNPCWPSPCSLLAQCSVSP-KGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPSNSTL 289
+ C +PC A C +P G+A C CP + G G D C ++G P
Sbjct: 350 HLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTG-GACDQDVDEC--SIGANPCEHLG 406
Query: 290 CVYQKPGQAFCTCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVTADGKTSCVCRESEV 349
G C C G C C ATC + G+ +C+C
Sbjct: 407 RCVNTQGSFLCQCGRGYTGPRCETDVN---ECLSGPCRNQATC-LDRIGQFTCICMAGFT 462
Query: 350 G 350
G
Sbjct: 463 G 463
Score = 95.5 bits (236), Expect = 6e-19
Identities = 84/271 (30%), Positives = 113/271 (41%), Gaps = 46/271 (16%)
Query: 720 CCKGFFGPDC-TQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGE 778
C +G+ GP C T S PC + C D I G C+C + G C + +
Sbjct: 419 CGRGYTGPRCETDVNECLSGPCRNQATCLDRI-GQFTCICMAGFTGTYCEVDI------D 471
Query: 779 QCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCV 838
+CQ G+C +R +G C TC GFSG C + +C T C A+CV
Sbjct: 472 ECQSSPCVNGGVCKDRV-NGFSC---TCPSGFSGSTCQLDVDECASTP----CRNGAKCV 523
Query: 839 SQEGVARCRCLDGFEG-----DGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHK 893
Q CRC +GFEG + C+P +PC H CV G + + C C
Sbjct: 524 DQPDGYECRCAEGFEGTLCDRNVDDCSP-DPCHH---------GRCVDG-IASFSCACAP 572
Query: 894 GWSGDGRVCVAIDECELD--MRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPC 951
G++G R +DEC GG D + Y+ C C G G + + ID C
Sbjct: 573 GYTGT-RCESQVDECRSQPCRHGGKCLDLVDKYL------CRCPSGTTGVNCEVN-IDDC 624
Query: 952 RAGNGGCHGLATCRAVGGGQRVCTCPPGFGG 982
A N G+ CR G + C C PGF G
Sbjct: 625 -ASNPCTFGV--CRD-GINRYDCVCQPGFTG 651
Score = 94.0 bits (232), Expect = 2e-18
Identities = 97/352 (27%), Positives = 127/352 (36%), Gaps = 88/352 (25%)
Query: 1271 KCVNCTRRF--RCTQGFQLQDTPRKSCVYRSGFSFSRGCSY-TCAKKIQVPDCC--PGFF 1325
KC++ ++ RC G T +C S C++ C I DC PGF
Sbjct: 596 KCLDLVDKYLCRCPSG-----TTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFT 650
Query: 1326 GTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNC---TGV 1382
G LC +C G G C +G +G C +C G P C +
Sbjct: 651 GPLCNV----------EINECASSPCGEGGS-CVDGENGFRC-LCPPGSLPPLCLPPSHP 698
Query: 1383 C---DCAHGLCQEGLQGDGSCVCNVGWQGLRCDQ-------------------------- 1413
C C+HG+C + G CVC GW G RC Q
Sbjct: 699 CAHEPCSHGICYDA-PGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFH 757
Query: 1414 ------------KITSPQCPRKCDPNANCVQDSAGASTCACAAGYSGNGIFCSEVDPCAH 1461
++ SP P C+ C C+C G+ G +VD CA
Sbjct: 758 CTCPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRC-QQDVDECA- 815
Query: 1462 GHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINSC----LIHHGGCHIHAECIPT 1517
G C PH CT +A G +CTC GY G Q+IN C ++ G C
Sbjct: 816 GPAPCGPHGICTNLA-GSFSCTCHGGYTGP-SCDQDINDCDPNPCLNGGSCQ-------D 866
Query: 1518 GPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKSTGDGQRTCTC 1569
G SCSC G++G R +D C N C P TC + TCTC
Sbjct: 867 GVGSFSCSCLPGFAGP--RCARDVDECLSN--PCGP-GTC-TDHVASFTCTC 912
Score = 93.6 bits (231), Expect = 2e-18
Identities = 78/256 (30%), Positives = 101/256 (39%), Gaps = 49/256 (19%)
Query: 1959 CCPGHYGSECQA----CPGGPSSPCSDRGVCMDGMSGSGQCLCRSGFAGTACELCAPGAF 2014
C PG G C C SSPC + G C+DG +G +CLC G + LC P +
Sbjct: 645 CQPGFTGPLCNVEINECA---SSPCGEGGSCVDGENGF-RCLCPPG---SLPPLCLPPSH 697
Query: 2015 GPHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEAVCRA-- 2072
+ C HG C + GG C C+ GW+GPRC L + PC C +
Sbjct: 698 PCAHEPCS---HGICYDAPGGF-RCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDG 753
Query: 2073 -GNSCECSLGYEGDGRVCTVADLCQDG---HGGCSEHANCSQVGTMVTCTCLPDYEG--- 2125
G C C G + GR C + C HGG E S G + C+C ++G
Sbjct: 754 MGFHCTCPPGVQ--GRQCELLSPCTPNPCEHGGRCE----SAPGQLPVCSCPQGWQGPRC 807
Query: 2126 --DGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGDGLQCLEESEPPVDR 2183
D C PC G G C+ A S C CH GY G + ++
Sbjct: 808 QQDVDECAGPAPC--GPHGICTNLAGSFS-------CTCHGGYTG------PSCDQDIND 852
Query: 2184 CLGQPPPCHSDAMCTD 2199
C P PC + C D
Sbjct: 853 C--DPNPCLNGGSCQD 866
Score = 92.4 bits (228), Expect = 5e-18
Identities = 86/314 (27%), Positives = 114/314 (36%), Gaps = 69/314 (21%)
Query: 720 CCKGFFGPDCTQCPGGFS-NPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGE 778
C G+ GP C Q NPC G+C DG+ G+ +C C P + G C + +
Sbjct: 837 CHGGYTGPSCDQDINDCDPNPCLNGGSCQDGV-GSFSCSCLPGFAGPRCA------RDVD 889
Query: 779 QCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCV 838
+C + C G C + S C TC PG+ G C + + DC P+ C CV
Sbjct: 890 ECLSN-PCGPGTCTDHVASF-TC---TCPPGYGGFHCEQDLPDCSPSS----CFNGGTCV 940
Query: 839 SQEGVARCRCLDGFEG-------------------------DGFSCTPSNPCSHP----- 868
C C G+ G GF CT + P
Sbjct: 941 DGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTL 1000
Query: 869 ----DRGGCSENAECVPGSLGTHHCTCHKGWSGDGRVC-VAIDEC-ELDMRGGCHTDALC 922
R C CV +C C GWS GR+C + C E + G + LC
Sbjct: 1001 VDWCSRQPCQNGGRCVQTGA---YCLCPPGWS--GRLCDIRSLPCREAAAQIGVRLEQLC 1055
Query: 923 SYVG-----PGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCP 977
G C C G G + +DPC A C TCR GG +C C
Sbjct: 1056 QAGGQCVDEDSSHYCVCPEGRTGSHCE-QEVDPCLA--QPCQHGGTCRGYMGGY-MCECL 1111
Query: 978 PGFGGDGFSCYGDI 991
PG+ GD +C D+
Sbjct: 1112 PGYNGD--NCEDDV 1123
Score = 92.0 bits (227), Expect = 7e-18
Identities = 63/204 (30%), Positives = 80/204 (39%), Gaps = 27/204 (13%)
Query: 153 PNRFGPDCQSVCSCVHGV-CNHGPRGDGSCLCFAGYTGPHCDQELPVCQELRCPQNTQCS 211
P P C C +G C P + +CLC G+ G C E P C C C
Sbjct: 36 PGAAAPPCLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLEDP-CHSGPCAGRGVCQ 94
Query: 212 AEAP------SCRCLPGYTQQGSECRAPNPCWPSPCSLLAQCSVSPKGQAQCHCPENYHG 265
+ SCRC G+ +G +C P+PC SPC+ A+CSV P G+ C CP Y G
Sbjct: 95 SSVVAGTARFSCRCPRGF--RGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQG 152
Query: 266 -----DGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPGLVSINSNASAGCFAF 320
D C +PC GG N+ PG C C G A
Sbjct: 153 RSCRSDVDECRVGEPCRH--GGTCLNT-------PGSFRCQCPAGYTGPLCENPA---VP 200
Query: 321 CSPFSCDRSATCQVTADGKTSCVC 344
C+P C TC+ + D C C
Sbjct: 201 CAPSPCRNGGTCRQSGDLTYDCAC 224
Score = 91.3 bits (225), Expect = 1e-17
Identities = 109/432 (25%), Positives = 151/432 (34%), Gaps = 94/432 (21%)
Query: 1947 HRNCVT--TTWKPSCCPGHYGSECQA-CPGGPSSPCSDRGVCMDGMSGSGQCLCRSGFAG 2003
H CV ++ +C PG+ G+ C++ S PC G C+D + C C SG G
Sbjct: 556 HGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLD-LVDKYLCRCPSGTTG 614
Query: 2004 TACELCAPGAFGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQL--------- 2054
CE+ C + CT G C +G+ C C G+TGP C V++
Sbjct: 615 VNCEVNIDD-----CASNPCTF-GVCRDGINRY-DCVCQPGFTGPLCNVEINECASSPCG 667
Query: 2055 -------------------ELQPVCTP---PCAPE----AVC---RAGNSCECSLGYEGD 2085
L P+C P PCA E +C G C C G+ G
Sbjct: 668 EGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGP 727
Query: 2086 GRVCTVA-DLCQDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWSCRARNPCTDGHRGGC 2144
++A D C+ C CS G CTC P +G C +PCT C
Sbjct: 728 RCSQSLARDACES--QPCRAGGTCSSDGMGFHCTCPPGVQGR--QCELLSPCTP---NPC 780
Query: 2145 SEHANCLSTGLNTRRCECHAGYVGDGLQCLEESEPPVDRCLGQPPPCHSDAMCTDLHFQE 2204
C S C C G+ G +C ++ VD C G P PC +CT+L
Sbjct: 781 EHGGRCESAPGQLPVCSCPQGW--QGPRCQQD----VDECAG-PAPCGPHGICTNL---- 829
Query: 2205 KRAGVFHLQATSGPYGLNFSEAEAACEAQ-----GAVLASFPQLSAAQQLGF-------- 2251
AG F G G + + C+ G+ S + GF
Sbjct: 830 --AGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARD 887
Query: 2252 -HLCLMGWLANGSTAHPVVFPVADCGNGRVGIVSLGARKNLSERWDAYCFR-------VQ 2303
CL G+ V C G G ++L + + CF V
Sbjct: 888 VDECLSNPCGPGTCTDHVASFTCTCPPGYGG---FHCEQDLPDCSPSSCFNGGTCVDGVN 944
Query: 2304 DVACRCRNGFVG 2315
+C CR G+ G
Sbjct: 945 SFSCLCRPGYTG 956
Score = 91.3 bits (225), Expect = 1e-17
Identities = 104/363 (28%), Positives = 129/363 (35%), Gaps = 53/363 (14%)
Query: 6 GLLPLCLLAFCLAGFSFVRGQVLFKGCDVKTTFVTHVPCTSCAAIKKQTCPSGWLRELPD 65
G LP+C C G+ R Q C H CT+ A TC G+ D
Sbjct: 791 GQLPVCS---CPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCD 847
Query: 66 QITQDCRYEVQLGGSMVSMSGCRRKCRKQVVQKACCPGYWGSRC----HECPGGAETPCN 121
Q DC L G C +C PG+ G RC EC PC
Sbjct: 848 QDINDCDPNPCLNGGSCQDGVGSFSC-------SCLPGFAGPRCARDVDEC---LSNPC- 896
Query: 122 GHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHG-VCNHGPRGDGS 180
G GTC D + + TC C + G C++ PDC S SC +G C G S
Sbjct: 897 GPGTCTDHV-ASFTCTCPPGYGGFHCEQDL------PDC-SPSSCFNGGTCVDGVNSF-S 947
Query: 181 CLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAPS--CRCLPGYTQQGSECRA-PNPCW 237
CLC GYTG HC E C C CSA P C CL +T G +C+ + C
Sbjct: 948 CLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFT--GPQCQTLVDWCS 1005
Query: 238 PSPCSLLAQCSVSPKGQAQCHCPENYHGDGMVC-LPKDPCTDNLGGCPSN-STLCVYQKP 295
PC +C + A C CP + G +C + PC + LC Q
Sbjct: 1006 RQPCQNGGRC---VQTGAYCLCPPGW--SGRLCDIRSLPCREAAAQIGVRLEQLC--QAG 1058
Query: 296 GQA-------FCTCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVTADGKTSCVCRESE 348
GQ +C C G + C C TC+ G C C
Sbjct: 1059 GQCVDEDSSHYCVCPEGRTGSHCEQEVDP---CLAQPCQHGGTCRGYMGG-YMCECLPGY 1114
Query: 349 VGD 351
GD
Sbjct: 1115 NGD 1117
Score = 89.7 bits (221), Expect = 3e-17
Identities = 77/280 (27%), Positives = 113/280 (40%), Gaps = 42/280 (15%)
Query: 719 GCCKGFFGPDCTQCPGGFS-------------NPCYGKGNCSDGIQGNGACLCFPDYKGI 765
G C G QCP G++ +PC G C C C P ++G
Sbjct: 172 GTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQ 231
Query: 766 ACHICSNPNKHGEQCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPT 825
C + + + G +C CV G+ CQ C P ++G+FC E + +C
Sbjct: 232 NCEV-NVDDCPGHRCLNGGTCVDGVNTYN------CQ---CPPEWTGQFCTEDVDECQLQ 281
Query: 826 GLAQHCHLHARCVSQEGVARCRCLDGFEGDGFSCTPS-NPCSHPDRGGCSENAECVPGSL 884
A CH C + G C C++G+ G+ SC+ + + C+ C A C +
Sbjct: 282 PNA--CHNGGTCFNTLGGHSCVCVNGWTGE--SCSQNIDDCA---TAVCFHGATC-HDRV 333
Query: 885 GTHHCTCHKGWSGDGRVCVAIDECELDMRGGCHTDALCSYVGP--GQSRCTCKLGFAGDG 942
+ +C C G + G +C D C + CH DA+C P G++ CTC GF G G
Sbjct: 334 ASFYCACPMGKT--GLLCHLDDAC---VSNPCHEDAICD-TNPVNGRAICTCPPGFTG-G 386
Query: 943 YQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGFGG 982
+D C G C L C G +C C G+ G
Sbjct: 387 ACDQDVDECSIGANPCEHLGRC-VNTQGSFLCQCGRGYTG 425
Score = 89.7 bits (221), Expect = 3e-17
Identities = 82/270 (30%), Positives = 111/270 (41%), Gaps = 39/270 (14%)
Query: 720 CCKGFFGPDCTQCPGGFSNP-CYGKGNCSDGIQGNGACLCFPDYKGIACHI----CSNPN 774
C G+ G C+Q + C+ C D + + C C G+ CH+ SNP
Sbjct: 302 CVNGWTGESCSQNIDDCATAVCFHGATCHDRV-ASFYCACPMGKTGLLCHLDDACVSNP- 359
Query: 775 KHGEQCQEDCGCVHGLCDNRPGSG-GVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHL 833
C ED +CD P +G +C TC PGF+G C++ + +C A C
Sbjct: 360 -----CHEDA-----ICDTNPVNGRAIC---TCPPGFTGGACDQDVDECSIG--ANPCEH 404
Query: 834 HARCVSQEGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHK 893
RCV+ +G C+C G+ G T N C G C A C+ +G C C
Sbjct: 405 LGRCVNTQGSFLCQCGRGYTGPRCE-TDVNECL---SGPCRNQATCL-DRIGQFTCICMA 459
Query: 894 GWSGDGRVC-VAIDECELDMRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCR 952
G++ G C V IDEC+ C +C G S CTC GF+G Q +D C
Sbjct: 460 GFT--GTYCEVDIDECQ---SSPCVNGGVCKDRVNGFS-CTCPSGFSGSTCQLD-VDEC- 511
Query: 953 AGNGGCHGLATCRAVGGGQRVCTCPPGFGG 982
+ C A C G C C GF G
Sbjct: 512 -ASTPCRNGAKCVDQPDGYE-CRCAEGFEG 539
Score = 88.2 bits (217), Expect = 9e-17
Identities = 84/335 (25%), Positives = 117/335 (34%), Gaps = 61/335 (18%)
Query: 55 CPSGWLRELPDQITQDCRYEVQLGGSMVSMSGCRRKCRKQVVQKAC-CP-GYWGSRCHEC 112
C +GW E Q DC V G+ C +V C CP G G CH
Sbjct: 302 CVNGWTGESCSQNIDDCATAVCFHGAT---------CHDRVASFYCACPMGKTGLLCHLD 352
Query: 113 PGGAETPCNGHGTC-LDGMDRNGTCVCQENFRGSACQE---------------------- 149
PC+ C + ++ C C F G AC +
Sbjct: 353 DACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQ 412
Query: 150 ----CQDPNRF-GPDCQS-VCSCVHGVCNHGPR-----GDGSCLCFAGYTGPHCDQELPV 198
CQ + GP C++ V C+ G C + G +C+C AG+TG +C+ ++
Sbjct: 413 GSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDE 472
Query: 199 CQELRCPQNTQCS--AEAPSCRCLPGYTQQGSECRAP-NPCWPSPCSLLAQCSVSPKGQA 255
CQ C C SC C G++ GS C+ + C +PC A+C P G
Sbjct: 473 CQSSPCVNGGVCKDRVNGFSCTCPSGFS--GSTCQLDVDECASTPCRNGAKCVDQPDGY- 529
Query: 256 QCHCPENYHGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPGLVSINSNASA 315
+C C E + +G +C D D+ P + CV C C PG +
Sbjct: 530 ECRCAEGF--EGTLC---DRNVDDCSPDPCHHGRCV-DGIASFSCACAPGYTGTRCESQV 583
Query: 316 GCFAFCSPFSCDRSATCQVTADGKTSCVCRESEVG 350
C C C D K C C G
Sbjct: 584 D---ECRSQPCRHGGKCLDLVD-KYLCRCPSGTTG 614
Score = 87.0 bits (214), Expect = 2e-16
Identities = 84/283 (29%), Positives = 106/283 (37%), Gaps = 50/283 (17%)
Query: 720 CCKGFFGPDCTQCPGGFSN-PCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGE 778
C + F GP C S PC G C +Q CLC P + G C I S P
Sbjct: 988 CLESFTGPQCQTLVDWCSRQPCQNGGRC---VQTGAYCLCPPGWSGRLCDIRSLP----- 1039
Query: 779 QCQEDCGCVHGLCDNRPGSGGVCQQG------TCAPGFSGRFCNESMGDCGPTGLAQHCH 832
C+E + + +GG C C G +G C + + C LAQ C
Sbjct: 1040 -CREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPC----LAQPCQ 1094
Query: 833 LHARCVSQEGVARCRCLDGFEGDGF-----SCTPSNPCSHPDRGGCSE-----NAECVPG 882
C G C CL G+ GD C S PC H G C + C PG
Sbjct: 1095 HGGTCRGYMGGYMCECLPGYNGDNCEDDVDECA-SQPCQH--GGSCIDLVARYLCSCPPG 1151
Query: 883 SLGTHHCTCHKGWSGDGRVCVAIDECELDMRGGCHTDALCSYVGPGQSRCTCKLGFAGDG 942
+LG C ++ G G LD C + C + G RCTC G+ G
Sbjct: 1152 TLGV-LCEINEDDCGPGP--------PLDSGPRCLHNGTCVDL-VGGFRCTCPPGYT--G 1199
Query: 943 YQC-SPIDPCRAGNGGCHGLAT--CRAVGGGQRVCTCPPGFGG 982
+C + I+ CR +G CH T C GG C C GF G
Sbjct: 1200 LRCEADINECR--SGACHAAHTRDCLQDPGGGFRCLCHAGFSG 1240
Score = 86.7 bits (213), Expect = 3e-16
Identities = 71/277 (25%), Positives = 107/277 (38%), Gaps = 41/277 (14%)
Query: 720 CCKGFFGPDCTQCPGGFSNPCYGKGNCSDGIQGNGA---CLCFPDYKGIACHI----CSN 772
C G+ G C S PC G+G C + A C C ++G C + S+
Sbjct: 67 CPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCLSS 126
Query: 773 PNKHGEQCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCH 832
P HG +C P +C +C PG+ GR C + +C + + C
Sbjct: 127 PCAHGARCSVG-----------PDGRFLC---SCPPGYQGRSCRSDVDEC---RVGEPCR 169
Query: 833 LHARCVSQEGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCH 892
C++ G RC+C G+ G P+ PC+ C C T+ C C
Sbjct: 170 HGGTCLNTPGSFRCQCPAGYTGP-LCENPAVPCA---PSPCRNGGTCRQSGDLTYDCACL 225
Query: 893 KGWSGDGRVC-VAIDEC--ELDMRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPID 949
G+ +G+ C V +D+C + GG D + +Y C C + G + +D
Sbjct: 226 PGF--EGQNCEVNVDDCPGHRCLNGGTCVDGVNTY------NCQCPPEWTGQ-FCTEDVD 276
Query: 950 PCRAGNGGCHGLATCRAVGGGQRVCTCPPGFGGDGFS 986
C+ CH TC GG C C G+ G+ S
Sbjct: 277 ECQLQPNACHNGGTCFNTLGGHS-CVCVNGWTGESCS 312
Score = 86.7 bits (213), Expect = 3e-16
Identities = 92/375 (24%), Positives = 135/375 (36%), Gaps = 67/375 (17%)
Query: 16 CLAGFSFVRGQVLFKGCDVKTTFVTHVPCTSCAAIKKQ------TCPSGWLRELPDQITQ 69
C+AGF+ C+V PC + K + TCPSG+
Sbjct: 457 CMAGFTGTY-------CEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGST------ 503
Query: 70 DCRYEVQLGGSMVSMSGCRRKCRKQVVQKACCPGYWGSRC-HECPGGAETPCNGHGTCLD 128
C+ +V S +G + + + C G+ G+ C + PC+ HG C+D
Sbjct: 504 -CQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCH-HGRCVD 561
Query: 129 GMDRNGTCVCQENFRGSACQ----ECQD-PNRFGPDC-----QSVCSCVHGV-------- 170
G+ + +C C + G+ C+ EC+ P R G C + +C C G
Sbjct: 562 GI-ASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVN 620
Query: 171 --------CNHGPRGDG----SCLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAPSCR 218
C G DG C+C G+TGP C+ E+ C C + C R
Sbjct: 621 IDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFR 680
Query: 219 CLPGYTQQGSECRAP-NPCWPSPCSLLAQCSVSPKGQAQCHCPENYHGDG-MVCLPKDPC 276
CL C P +PC PCS C +P G +C C + G L +D C
Sbjct: 681 CLCPPGSLPPLCLPPSHPCAHEPCS-HGICYDAP-GGFRCVCEPGWSGPRCSQSLARDAC 738
Query: 277 TDNLGGCPSNSTLCVYQKPGQAF-CTCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVT 335
C + T G F CTC PG+ + C+P C+ C+
Sbjct: 739 ESQ--PCRAGGTC---SSDGMGFHCTCPPGV----QGRQCELLSPCTPNPCEHGGRCESA 789
Query: 336 ADGKTSCVCRESEVG 350
C C + G
Sbjct: 790 PGQLPVCSCPQGWQG 804
Score = 85.9 bits (211), Expect = 5e-16
Identities = 80/291 (27%), Positives = 104/291 (35%), Gaps = 68/291 (23%)
Query: 1318 PDCCPGFFGTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGP 1377
P C CE P GG CS G C C G G CE+ L P
Sbjct: 727 PRCSQSLARDACESQPCRAGGTCSSDGM-------GFHCTCPPGVQGRQCEL--LSPCTP 777
Query: 1378 NCTGVCDCAHGLCQEGLQGD-GSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAG 1436
N C HG E G C C GWQG RC Q + P C P+ C + AG
Sbjct: 778 N-----PCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICT-NLAG 831
Query: 1437 ASTCACAAGYSG----NGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDG 1492
+ +C C GY+G I + +PC +G G C G +C+C G+ G
Sbjct: 832 SFSCTCHGGYTGPSCDQDINDCDPNPCLNG-GSCQD-------GVGSFSCSCLPGFAGP- 882
Query: 1493 ELCQEINSCLIH---------------------HGGCHIH---AECIPT----------G 1518
++++ CL + +GG H +C P+ G
Sbjct: 883 RCARDVDECLSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDG 942
Query: 1519 PQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKSTGDGQRTCTC 1569
SC CR GY+G + DPC C C + G R CTC
Sbjct: 943 VNSFSCLCRPGYTGAHCQ--HEADPCLSR--PCLHGGVCSAAHPGFR-CTC 988
Score = 85.1 bits (209), Expect = 8e-16
Identities = 86/304 (28%), Positives = 111/304 (36%), Gaps = 75/304 (24%)
Query: 1943 GRGCHRNCVTTTWKPSCCPGHYGSECQACPGGPSSPCSDRGVC-MDGMSGSGQCLCRSGF 2001
G CH ++ +C G G C S+PC + +C + ++G C C GF
Sbjct: 326 GATCHDR--VASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGF 383
Query: 2002 AGTACEL----CAPGAFGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQ 2057
G AC+ C+ GA P C GRC GS C C G+TGPRCE ++
Sbjct: 384 TGGACDQDVDECSIGA-NP------CEHLGRC-VNTQGSFLCQCGRGYTGPRCET--DVN 433
Query: 2058 PVCTPPCAPEAVC--RAGN-SCECSLGYEGDGRVCTV-ADLCQDGHGGCSEHANCSQVGT 2113
+ PC +A C R G +C C G+ G C V D CQ C C
Sbjct: 434 ECLSGPCRNQATCLDRIGQFTCICMAGF--TGTYCEVDIDECQS--SPCVNGGVCKDRVN 489
Query: 2114 MVTCTCLPDYEG-------------------------DGWSCRARNPCTDGHRG------ 2142
+CTC + G DG+ CR C +G G
Sbjct: 490 GFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECR----CAEGFEGTLCDRN 545
Query: 2143 --GCS----EHANCLSTGLNTRRCECHAGYVGDGLQCLEESEPPVDRCLGQPPPCHSDAM 2196
CS H C+ G+ + C C GY G E VD C Q PC
Sbjct: 546 VDDCSPDPCHHGRCVD-GIASFSCACAPGYTG------TRCESQVDECRSQ--PCRHGGK 596
Query: 2197 CTDL 2200
C DL
Sbjct: 597 CLDL 600
Score = 84.3 bits (207), Expect = 1e-15
Identities = 85/341 (24%), Positives = 115/341 (33%), Gaps = 52/341 (15%)
Query: 40 THVPCTSCAAIKKQTCPSGWLRELPDQITQDCRYEVQLGGSMVSMSGCRRKCRKQVVQKA 99
T +P A + CP GW+ E Q+ C G C+ + +
Sbjct: 56 TQLPSREAACL----CPPGWVGERC-QLEDPCH-----SGPCAGRGVCQSSVVAGTARFS 105
Query: 100 C-CP-GYWGSRCHECPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFG 157
C CP G+ G C +PC C G D C C ++G +C+ D R G
Sbjct: 106 CRCPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVG 165
Query: 158 PDCQSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAP-- 215
C+ G C + P G C C AGYTGP C+ C C C
Sbjct: 166 EPCRH-----GGTCLNTP-GSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLT 219
Query: 216 -SCRCLPGYTQQGSECRAPNPCWPSPCSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKD 274
C CLPG+ +G C P L V C CP + G
Sbjct: 220 YDCACLPGF--EGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQF------- 270
Query: 275 PCTDNLGGCPSNSTLC-----VYQKPGQAFCTCRPGLV------SINSNASAGCF--AFC 321
CT+++ C C + G C C G +I+ A+A CF A C
Sbjct: 271 -CTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATC 329
Query: 322 SPFSCDRSATCQVTADGKTSCVCRESEVGDGRACYGHLLHE 362
C + GKT +C + AC + HE
Sbjct: 330 HDRVASFYCACPM---GKTGLLCHLDD-----ACVSNPCHE 362
Score = 80.9 bits (198), Expect = 2e-14
Identities = 81/300 (27%), Positives = 105/300 (35%), Gaps = 67/300 (22%)
Query: 1320 CCPGFFGTLCE-------PCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCEL 1372
C G+ G LCE P P GG C G + +C C GF G CEV
Sbjct: 185 CPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDL------TYDCACLPGFEGQNCEVNV- 237
Query: 1373 GRYGPNCTGVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQC-PRKCDPNANCV 1431
+C G G C +G+ +C C W G C + + Q P C C
Sbjct: 238 ----DDCPGHRCLNGGTCVDGVN-TYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCF 292
Query: 1432 QDSAGASTCACAAGYSGNGIFCSE-VDPCAHG---HGG---------------------- 1465
++ G +C C G++G CS+ +D CA HG
Sbjct: 293 -NTLGGHSCVCVNGWTGES--CSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLC 349
Query: 1466 ----------CSPHANC-TKVAPGQRTCTCQDGYMGDGELCQEINSCLIHHGGCHIHAEC 1514
C A C T G+ CTC G+ G G Q+++ C I C C
Sbjct: 350 HLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTG-GACDQDVDECSIGANPCEHLGRC 408
Query: 1515 IPTGPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKSTGDGQRTCTCDTAHT 1574
+ T C C GY+G T D +G C ATC GQ TC C T
Sbjct: 409 VNT-QGSFLCQCGRGYTGPRCET----DVNECLSGPCRNQATCLDR-IGQFTCICMAGFT 462
Score = 80.9 bits (198), Expect = 2e-14
Identities = 92/330 (27%), Positives = 124/330 (37%), Gaps = 64/330 (19%)
Query: 1272 CVNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKKIQVPDCCPGFFGTLCEP 1331
CVN C+Q + D C + R S+ CA C G G LC
Sbjct: 302 CVNGWTGESCSQN--IDDCATAVC-FHGATCHDRVASFYCA-------CPMGKTGLLCHL 351
Query: 1332 CPGGLGGVCSGHGQCQDRFL-GSGECHCHEGFHGTACEVCELGRYGPNCT-GVCDCAH-G 1388
+ C C + G C C GF G AC+ + C+ G C H G
Sbjct: 352 DDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACD-----QDVDECSIGANPCEHLG 406
Query: 1389 LCQEGLQGDGSCVCNVGWQGLRCDQKITSPQC-PRKCDPNANCVQDSAGASTCACAAGYS 1447
C QG C C G+ G RC+ + +C C A C+ D G TC C AG++
Sbjct: 407 RCVN-TQGSFLCQCGRGYTGPRCETDVN--ECLSGPCRNQATCL-DRIGQFTCICMAGFT 462
Query: 1448 GNGIFCSEVD-------PCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQ-EIN 1499
G +C EVD PC +G G C N +CTC G+ G CQ +++
Sbjct: 463 GT--YC-EVDIDECQSSPCVNG-GVCKDRVN-------GFSCTCPSGF--SGSTCQLDVD 509
Query: 1500 SCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSP----YA 1555
C C A+C+ P C C EG+ G C +N CSP +
Sbjct: 510 ECA--STPCRNGAKCVDQ-PDGYECRCAEGFEG---------TLCDRNVDDCSPDPCHHG 557
Query: 1556 TCKSTGDGQRTCTCDTAHTVGDGLTCRARV 1585
C G +C C +T G C ++V
Sbjct: 558 RCVD-GIASFSCACAPGYT---GTRCESQV 583
Score = 77.0 bits (188), Expect = 2e-13
Identities = 81/278 (29%), Positives = 106/278 (38%), Gaps = 52/278 (18%)
Query: 1320 CCPGFFGTLCE----PCPGG-------LGGVCSGHGQCQDRFLGSGECHCHEGFHGTACE 1368
C PG+ G LC+ PC L +C GQC D S C C EG G+ CE
Sbjct: 1024 CPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDED-SSHYCVCPEGRTGSHCE 1082
Query: 1369 VCELGRYGPNCTGVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQC-PRKCDPN 1427
+ C C HG G G C C G+ G C+ + +C + C
Sbjct: 1083 -----QEVDPCLAQ-PCQHGGTCRGYMGGYMCECLPGYNGDNCEDDV--DECASQPCQHG 1134
Query: 1428 ANCVQDSAGASTCACAAGYSGNGIFCS-EVDPCAHG-----HGGCSPHANCTKVAPGQRT 1481
+C+ D C+C G G+ C D C G C + C + G R
Sbjct: 1135 GSCI-DLVARYLCSCPPGTL--GVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFR- 1190
Query: 1482 CTCQDGYMGDGELCQ-EINSCLIHHGGCHI--HAECIPTGPQQVSCSCREGYSGDGIRTC 1538
CTC GY G C+ +IN C G CH +C+ C C G+SG +T
Sbjct: 1191 CTCPPGY--TGLRCEADINEC--RSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQT- 1245
Query: 1539 ELLDPCS----KNNGGCSPYATCKSTGDG---QRTCTC 1569
+L PC ++ G C P S G G TC C
Sbjct: 1246 -VLSPCESQPCQHGGQCRP-----SPGPGGGLTFTCHC 1277
Score = 76.3 bits (186), Expect = 4e-13
Identities = 96/339 (28%), Positives = 118/339 (34%), Gaps = 83/339 (24%)
Query: 1279 FRCTQGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKKIQVPDCCPGFFGTLCE----PC-- 1332
F C Q L D SC + G S++C C PG+ G C+ PC
Sbjct: 919 FHCEQ--DLPDCSPSSC-FNGGTCVDGVNSFSCL-------CRPGYTGAHCQHEADPCLS 968
Query: 1333 -PGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCTGVCD-CAHGLC 1390
P GGVCS H GF T E GP C + D C+ C
Sbjct: 969 RPCLHGGVCSA---------------AHPGFRCTCLESFT----GPQCQTLVDWCSRQPC 1009
Query: 1391 QEG---LQGDGSCVCNVGWQGLRCDQKITSPQC-----------PRKCDPNANCVQDSAG 1436
Q G +Q C+C GW G CD I S C + C CV D
Sbjct: 1010 QNGGRCVQTGAYCLCPPGWSGRLCD--IRSLPCREAAAQIGVRLEQLCQAGGQCV-DEDS 1066
Query: 1437 ASTCACAAGYSGNGIFC-SEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELC 1495
+ C C G +G+ C EVDPC H + G C C GY GD C
Sbjct: 1067 SHYCVCPEGRTGS--HCEQEVDPCL---AQPCQHGGTCRGYMGGYMCECLPGYNGDN--C 1119
Query: 1496 Q-EINSCL---IHHGGCHI-----HAECIPTGPQQVSCSCREGYSGDGIRTCELLDPCSK 1546
+ +++ C HGG I + P G V C E G G P
Sbjct: 1120 EDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPG--------PPLD 1171
Query: 1547 NNGGCSPYATCKSTGDGQRTCTCDTAHTVGDGLTCRARV 1585
+ C TC G R CTC +T GL C A +
Sbjct: 1172 SGPRCLHNGTCVDLVGGFR-CTCPPGYT---GLRCEADI 1206
Score = 75.1 bits (183), Expect = 8e-13
Identities = 76/260 (29%), Positives = 93/260 (35%), Gaps = 35/260 (13%)
Query: 106 GSRCHECPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCS 165
G+ C G+ PC G C R C+C + G CQ +DP GP C
Sbjct: 37 GAAAPPCLDGS--PCANGGRCTQLPSREAACLCPPGWVGERCQ-LEDPCHSGP-CAGRGV 92
Query: 166 CVHGVCNHGPRGDGSCLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAPS---CRCLPG 222
C V R SC C G+ GP C P C C +CS C C PG
Sbjct: 93 CQSSVVAGTAR--FSCRCPRGFRGPDCSLPDP-CLSSPCAHGARCSVGPDGRFLCSCPPG 149
Query: 223 YTQQGSECRAP-NPC-WPSPCSLLAQCSVSPKGQAQCHCPENYHG-----DGMVCLPKDP 275
Y QG CR+ + C PC C +P G +C CP Y G + C P P
Sbjct: 150 Y--QGRSCRSDVDECRVGEPCRHGGTCLNTP-GSFRCQCPAGYTGPLCENPAVPCAP-SP 205
Query: 276 CTDNLGGCPSNSTLCVYQKPGQAFCTCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVT 335
C N G C + L Y C C PG N + C C TC
Sbjct: 206 CR-NGGTCRQSGDL-TYD------CACLPGFEGQNCEVNVD---DCPGHRCLNGGTC--- 251
Query: 336 ADGKTSCVCRESEVGDGRAC 355
DG + C+ G+ C
Sbjct: 252 VDGVNTYNCQCPPEWTGQFC 271
Score = 75.1 bits (183), Expect = 8e-13
Identities = 89/330 (26%), Positives = 103/330 (31%), Gaps = 109/330 (33%)
Query: 1959 CCPGHYGSECQACPGGP--SSPCSDRGVCMDGMSGSGQCLCRSGFAGTACE--------- 2007
C PG+ G+ CQ P S PC GVC G +C C F G C+
Sbjct: 950 CRPGYTGAHCQH-EADPCLSRPCLHGGVCSAAHPGF-RCTCLESFTGPQCQTLVDWCSRQ 1007
Query: 2008 ---------------LCAPGAFGPHCQA----CR-------------CTVHGRC-DEGLG 2034
LC PG G C CR C G+C DE
Sbjct: 1008 PCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDED-- 1065
Query: 2035 GSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEAVCRA---GNSCECSLGYEGD------ 2085
S C C EG TG CE E+ P PC CR G CEC GY GD
Sbjct: 1066 SSHYCVCPEGRTGSHCEQ--EVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDV 1123
Query: 2086 ----------GRVC--------------TVADLCQDGHGGCS------EHANCSQVGTMV 2115
G C T+ LC+ C C GT V
Sbjct: 1124 DECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCV 1183
Query: 2116 T------CTCLPDYEGDGWSCRARNPCTDGHRGGC--SEHANCLSTGLNTRRCECHAGYV 2167
CTC P Y G R + G C + +CL RC CHAG+
Sbjct: 1184 DLVGGFRCTCPPGYTG----LRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFS 1239
Query: 2168 GDGLQCLEESEPPVDRCLGQPPPCHSDAMC 2197
G Q + + C Q PC C
Sbjct: 1240 GPRCQTV------LSPCESQ--PCQHGGQC 1261
Score = 74.7 bits (182), Expect = 1e-12
Identities = 82/301 (27%), Positives = 109/301 (36%), Gaps = 66/301 (21%)
Query: 1311 CAKKIQVPDC-CP-GFFGTLCEPCPGGLGGV-CSGHGQCQDRFLGSGECHCHEGFHGTAC 1367
C ++ C CP GF G+ C+ C +C D+ G EC C EGF GT C
Sbjct: 484 CKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGY-ECRCAEGFEGTLC 542
Query: 1368 EVCELGRYGPNCTGVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPN 1427
+ R +C+ C HG C +G+ SC C G+ G RC+ ++ + + C
Sbjct: 543 D-----RNVDDCS-PDPCHHGRCVDGI-ASFSCACAPGYTGTRCESQVDECR-SQPCRHG 594
Query: 1428 ANCVQDSAGASTCACAAGYSGNGIFCS-EVDPCAHG---HGGCSPHANCTKVAPGQRTCT 1483
C+ D C C +G + G+ C +D CA G C N + C
Sbjct: 595 GKCL-DLVDKYLCRCPSGTT--GVNCEVNIDDCASNPCTFGVCRDGIN-------RYDCV 644
Query: 1484 CQDGYMGDGELCQ-EINSCL---IHHGGCHIHAE---------------CIP-------- 1516
CQ G+ G LC EIN C GG + E C+P
Sbjct: 645 CQPGF--TGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHE 702
Query: 1517 --------TGPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKSTGDGQRTCT 1568
P C C G+SG D C C TC S G G CT
Sbjct: 703 PCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQ--PCRAGGTCSSDGMGFH-CT 759
Query: 1569 C 1569
C
Sbjct: 760 C 760
Score = 74.7 bits (182), Expect = 1e-12
Identities = 75/243 (30%), Positives = 93/243 (38%), Gaps = 29/243 (11%)
Query: 1319 DCCPGFFGTLCEPCPGGLGGV-CSGHGQCQD---RFLGSGECHCHEGFHGTACEVCELG- 1373
+C PG+ G CE C G C D R+L C C G G CE+ E
Sbjct: 1109 ECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYL----CSCPPGTLGVLCEINEDDC 1164
Query: 1374 RYGPNCTGVCDCAH-GLCQEGLQGDGSCVCNVGWQGLRCDQKIT---SPQCPRKCDPNAN 1429
GP C H G C + L G C C G+ GLRC+ I S C +
Sbjct: 1165 GPGPPLDSGPRCLHNGTCVD-LVGGFRCTCPPGYTGLRCEADINECRSGAC--HAAHTRD 1221
Query: 1430 CVQDSAGASTCACAAGYSG----NGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQ 1485
C+QD G C C AG+SG + E PC HG G C P G T TC
Sbjct: 1222 CLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHG-GQCRPSPG----PGGGLTFTCH 1276
Query: 1486 DGYMGDGELCQEI-NSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLDPC 1544
G C+ + SC C + C T P+ C+C G SG R+ P
Sbjct: 1277 CAQPFWGPRCERVARSC--RELQCPVGVPCQQT-PRGPRCACPPGLSGPSCRSFPGSPPG 1333
Query: 1545 SKN 1547
+ N
Sbjct: 1334 ASN 1336
Score = 74.3 bits (181), Expect = 1e-12
Identities = 64/208 (30%), Positives = 84/208 (40%), Gaps = 31/208 (14%)
Query: 1373 GRYGPNCTGVCDCAHG-LCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCV 1431
G P C CA+G C + + +C+C GW G RC ++ P C C
Sbjct: 37 GAAAPPCLDGSPCANGGRCTQLPSREAACLCPPGWVGERC--QLEDPCHSGPCAGRGVC- 93
Query: 1432 QDSAGAST----CACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDG 1487
Q S A T C C G+ G CS DPC C+ A C+ G+ C+C G
Sbjct: 94 QSSVVAGTARFSCRCPRGFRGPD--CSLPDPCL--SSPCAHGARCSVGPDGRFLCSCPPG 149
Query: 1488 YMG-----DGELCQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCE-LL 1541
Y G D + C+ C HGG C+ T P C C GY+G CE
Sbjct: 150 YQGRSCRSDVDECRVGEPC--RHGG-----TCLNT-PGSFRCQCPAGYTGP---LCENPA 198
Query: 1542 DPCSKNNGGCSPYATCKSTGDGQRTCTC 1569
PC+ + C TC+ +GD C C
Sbjct: 199 VPCAPS--PCRNGGTCRQSGDLTYDCAC 224
Score = 73.6 bits (179), Expect = 2e-12
Identities = 70/248 (28%), Positives = 91/248 (36%), Gaps = 28/248 (11%)
Query: 1326 GTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCTGVCDC 1385
G PC G C+ G+C C C G+ G C++ + GP C G
Sbjct: 37 GAAAPPCLDG--SPCANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGP-CAG---- 89
Query: 1386 AHGLCQEGLQGDG---SCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTCAC 1442
G+CQ + SC C G++G C + P C A C G C+C
Sbjct: 90 -RGVCQSSVVAGTARFSCRCPRGFRGPDC--SLPDPCLSSPCAHGARCSVGPDGRFLCSC 146
Query: 1443 AAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINSCL 1502
GY G S+VD C G C C PG C C GY G LC E +
Sbjct: 147 PPGYQGRSC-RSDVDECRVGE-PCRHGGTCLN-TPGSFRCQCPAGY--TGPLC-ENPAVP 200
Query: 1503 IHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCEL-LDPCSKNNGGCSPYATCKSTG 1561
C C +G C+C G+ G + CE+ +D C + C TC
Sbjct: 201 CAPSPCRNGGTCRQSGDLTYDCACLPGFEG---QNCEVNVDDCPGHR--CLNGGTCV--- 252
Query: 1562 DGQRTCTC 1569
DG T C
Sbjct: 253 DGVNTYNC 260
Score = 73.6 bits (179), Expect = 2e-12
Identities = 70/238 (29%), Positives = 86/238 (36%), Gaps = 42/238 (17%)
Query: 1958 SCCPGHYGSECQA----CPGGP---SSP-CSDRGVCMDGMSGSGQCLCRSGFAGTACEL- 2008
SC PG G C+ C GP S P C G C+D + G +C C G+ G CE
Sbjct: 1147 SCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVD-LVGGFRCTCPPGYTGLRCEAD 1205
Query: 2009 ---CAPGAFGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPVCTPPCA 2065
C GA C C + GG C C G++GPRC Q L P + PC
Sbjct: 1206 INECRSGA-------CHAAHTRDCLQDPGGGFRCLCHAGFSGPRC--QTVLSPCESQPCQ 1256
Query: 2066 PEAVCRAGN--------SCECSLGYEGDGRVCTVADLCQDGHGGCSEHANCSQVGTMVTC 2117
CR +C C+ + G R VA C++ C C Q C
Sbjct: 1257 HGGQCRPSPGPGGGLTFTCHCAQPFWGP-RCERVARSCRELQ--CPVGVPCQQTPRGPRC 1313
Query: 2118 TCLPDYEGDGWSCRARNPCTDGHRGGCSEHANCLSTG-------LNTRRCECHAGYVG 2168
C P G SCR+ G A CL G RC C G+ G
Sbjct: 1314 ACPPGLSGP--SCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTG 1369
Score = 72.8 bits (177), Expect = 4e-12
Identities = 79/309 (25%), Positives = 107/309 (34%), Gaps = 100/309 (32%)
Query: 1958 SCCPGHYGSEC-QACPGGPSSPCSDRGVCMDGMSGSGQCLCRSGFAGTACE--------- 2007
+C PG+ G C Q P S C + G C+DG++ S CLCR G+ G C+
Sbjct: 911 TCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVN-SFSCLCRPGYTGAHCQHEADPCLSR 969
Query: 2008 -----------------LCAPGAFGPHCQAC-------RCTVHGRCDEGLGGSGSCFCDE 2043
C GP CQ C GRC + C C
Sbjct: 970 PCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQT---GAYCLCPP 1026
Query: 2044 GWTGPRCEVQLELQPVCTPPCAP---------EAVCRAGNSCECSLGYEGDGRVCTVADL 2094
GW+G C+++ + PC E +C+AG C E C +
Sbjct: 1027 GWSGRLCDIR-------SLPCREAAAQIGVRLEQLCQAGGQCV----DEDSSHYC----V 1071
Query: 2095 CQDGHGG--CSEHAN------CSQVGTM------VTCTCLPDYEGDGWSCR------ARN 2134
C +G G C + + C GT C CLP Y GD +C A
Sbjct: 1072 CPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGD--NCEDDVDECASQ 1129
Query: 2135 PCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGDGLQCLEES---EPPVDRCLGQPPPC 2191
PC H G C + + C C G +G + E+ PP+D P C
Sbjct: 1130 PCQ--HGGSCIDL-------VARYLCSCPPGTLGVLCEINEDDCGPGPPLD----SGPRC 1176
Query: 2192 HSDAMCTDL 2200
+ C DL
Sbjct: 1177 LHNGTCVDL 1185
Score = 72.4 bits (176), Expect = 5e-12
Identities = 69/254 (27%), Positives = 84/254 (33%), Gaps = 28/254 (11%)
Query: 1959 CCPGHYGSECQA-CPGGPSSPCSDRGVCMDGMSGSGQCLCRSGFAGTACEL----CAPGA 2013
C PG+ G C+ S PC G C+D + C C G G CE+ C PG
Sbjct: 1110 CLPGYNGDNCEDDVDECASQPCQHGGSCID-LVARYLCSCPPGTLGVLCEINEDDCGPGP 1168
Query: 2014 FGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEAVCR-- 2071
P RC +G C + +GG C C G+TG RCE + C A R
Sbjct: 1169 --PLDSGPRCLHNGTCVDLVGGF-RCTCPPGYTGLRCEADIN---ECRSGACHAAHTRDC 1222
Query: 2072 -----AGNSCECSLGYEGDGRVCTVADLCQDG---HGGCSEHANCSQVGTMVTCTCLPDY 2123
G C C G+ G R TV C+ HGG + G TC C +
Sbjct: 1223 LQDPGGGFRCLCHAGFSGP-RCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPF 1281
Query: 2124 EGDGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGDGLQCLEESEPPVDR 2183
W R C C T R C C G G + S P
Sbjct: 1282 ----WGPRCERVARSCRELQCPVGVPCQQTPRGPR-CACPPGLSGPSCRSFPGSPPGASN 1336
Query: 2184 CLGQPPPCHSDAMC 2197
PC C
Sbjct: 1337 ASCAAAPCLHGGSC 1350
Score = 71.6 bits (174), Expect = 9e-12
Identities = 76/315 (24%), Positives = 96/315 (30%), Gaps = 66/315 (20%)
Query: 100 CCPGYWGSRCH----ECPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNR 155
C PGY G C EC A PC G+C+D + R C C G C+ +D
Sbjct: 1110 CLPGYNGDNCEDDVDEC---ASQPCQHGGSCIDLVARY-LCSCPPGTLGVLCEINEDDCG 1165
Query: 156 FGPDCQSVCSCVH---------------------------------GVCN--------HG 174
GP S C+H G C+
Sbjct: 1166 PGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQD 1225
Query: 175 PRGDGSCLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAP-------SCRCLPGYTQQG 227
P G CLC AG++GP C L C+ C QC +C C + G
Sbjct: 1226 PGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPF--WG 1283
Query: 228 SEC-RAPNPCWPSPCSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPSN 286
C R C C + C +P+G +C CP G P P + C +
Sbjct: 1284 PRCERVARSCRELQCPVGVPCQQTPRG-PRCACPPGLSGPSCRSFPGSPPGASNASCAAA 1342
Query: 287 STL---CVYQKPGQAF--CTCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVTADGKTS 341
L P F C C G A A C R+A D +
Sbjct: 1343 PCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCD 1402
Query: 342 CVCRESEVG-DGRAC 355
C G DG C
Sbjct: 1403 RECNSPGCGWDGGDC 1417
Score = 71.2 bits (173), Expect = 1e-11
Identities = 82/263 (31%), Positives = 95/263 (36%), Gaps = 56/263 (21%)
Query: 1941 GLGRGCHRNCVTTTWKPSC-----------CPGHYGSECQACPGGPSSPCSDRGVCMDGM 1989
GL CH C W P C CP G CQ P GP R C G+
Sbjct: 1270 GLTFTCH--CAQPFWGPRCERVARSCRELQCP--VGVPCQQTPRGP------RCACPPGL 1319
Query: 1990 SGSGQCLCRSGFAGTACELCAPGAFGPHCQACRCTVHGRCDEG-LGGSGSCFCDEGWTGP 2048
SG CRS F G+ PGA C A C G C L C C +GWTGP
Sbjct: 1320 SGPS---CRS-FPGSP-----PGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGP 1370
Query: 2049 RCEVQLELQPVCTPPCAPEAVC---RAGNSC--EC-SLGYEGDGRVCTVADLCQDGHGGC 2102
RCE V P P A C R C EC S G DG C+++ D C
Sbjct: 1371 RCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDRECNSPGCGWDGGDCSLS--VGDPWRQC 1428
Query: 2103 SEHANCSQVGTMVTC---TCLPDYEGDGWSCRA---RNPCTDGHRGGCSEH---ANCLST 2153
E C ++ C P D + C A C + C++H C
Sbjct: 1429 -EALQCWRLFNNSRCDPACSSPACLYDNFDCHAGGRERTCNPVYEKYCADHFADGRC-DQ 1486
Query: 2154 GLNTRRCECHAGYVGDGLQCLEE 2176
G NT C G+ DGL C E
Sbjct: 1487 GCNTEEC----GW--DGLDCASE 1503
Score = 68.9 bits (167), Expect = 6e-11
Identities = 64/225 (28%), Positives = 77/225 (34%), Gaps = 30/225 (13%)
Query: 100 CCPGYWGSRCH----ECPGGA-------ETPCNGHGTCLDGMDRNGTCVCQENFRGSACQ 148
C PG+ G C C A E C G C+D D + CVC E GS C+
Sbjct: 1024 CPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDE-DSSHYCVCPEGRTGSHCE 1082
Query: 149 ECQDPNRFGPDCQSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQELPVCQELRCPQNT 208
+ DP P C HG G G C C GY G +C+ ++ C C
Sbjct: 1083 QEVDPCLAQP-------CQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGG 1135
Query: 209 QC--SAEAPSCRCLPGYTQ-----QGSECRAPNPCWPSPCSLLAQCSVSPKGQAQCHCPE 261
C C C PG +C P P L V G +C CP
Sbjct: 1136 SCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPP 1195
Query: 262 NYHGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAF-CTCRPG 305
Y G+ C D G C + T Q PG F C C G
Sbjct: 1196 GY--TGLRC-EADINECRSGACHAAHTRDCLQDPGGGFRCLCHAG 1237
Score = 63.5 bits (153), Expect = 3e-09
Identities = 92/365 (25%), Positives = 114/365 (31%), Gaps = 86/365 (23%)
Query: 664 GSCVDCQALNTSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKGCASYCNQTIMEQGCCKG 723
GSC+D A +CPP ++ G N+
Sbjct: 1135 GSCIDLVARYLCSCPPGTL-----------------------GVLCEINE---------- 1161
Query: 724 FFGPDCTQCPGGFSNP-CYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQCQE 782
DC P S P C G C D + G C C P Y G+ C N + G
Sbjct: 1162 ---DDCGPGPPLDSGPRCLHNGTCVD-LVGGFRCTCPPGYTGLRCEADINECRSGA---- 1213
Query: 783 DCGCVHGL-CDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQE 841
C H C PG G C C GFSG C + C +Q C +C
Sbjct: 1214 -CHAAHTRDCLQDPGGGFRC---LCHAGFSGPRCQTVLSPCE----SQPCQHGGQCRPSP 1265
Query: 842 G-----VARCRCLDGFEGD----------GFSCTPSNPCSHPDRGGCSENAECVPGSLGT 886
G C C F G C PC RG C PG G
Sbjct: 1266 GPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRG---PRCACPPGLSGP 1322
Query: 887 HHCTCHKGWSGDGRVCVAIDECELDMRGG-CHTDALCSYVGPGQSRCTCKLGFAGDGYQC 945
+ G A C + GG C L + RC C G+ G +
Sbjct: 1323 SCRSFPGSPPGASNASCAAAPC---LHGGSCRPAPLAPFF-----RCACAQGWTGPRCEA 1374
Query: 946 SPIDPCRAGNGGCHGLATCRAVGGGQRV---CTCPPGFGGDGFSC---YGDIFRELEANA 999
P + C A C+A G QR C PG G DG C GD +R+ EA
Sbjct: 1375 PAAAPEVSEEPRC-PRAACQAKRGDQRCDRECN-SPGCGWDGGDCSLSVGDPWRQCEALQ 1432
Query: 1000 HFSIF 1004
+ +F
Sbjct: 1433 CWRLF 1437
Score = 62.8 bits (151), Expect = 4e-09
Identities = 97/378 (25%), Positives = 118/378 (31%), Gaps = 121/378 (32%)
Query: 1320 CCPGFFGTLCE----PCPGG----LGGVCSGHGQCQDRFLGSGECHCHEGFHGTACE--- 1368
C PG G LCE C G G C +G C D +G C C G+ G CE
Sbjct: 1148 CPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVD-LVGGFRCTCPPGYTGLRCEADI 1206
Query: 1369 --------------------------VCELGRYGPNC-TGVCDCAHGLCQEGLQGDGSCV 1401
+C G GP C T + C CQ G G C
Sbjct: 1207 NECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHG----GQCR 1262
Query: 1402 CNVGWQG-----LRCDQKITSPQCPR--------KCDPNANCVQDSAGASTCACAAGYSG 1448
+ G G C Q P+C R +C C Q G CAC G SG
Sbjct: 1263 PSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPR-CACPPGLSG 1321
Query: 1449 -------------NGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDG--- 1492
+ C+ PC HG G C P +AP R C C G+ G
Sbjct: 1322 PSCRSFPGSPPGASNASCAAA-PCLHG-GSCRP----APLAPFFR-CACAQGWTGPRCEA 1374
Query: 1493 -----ELCQEIN----SCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLDP 1543
E+ +E +C G EC G C GD R CE L
Sbjct: 1375 PAAAPEVSEEPRCPRAACQAKRGDQRCDRECNSPGCGWDGGDCSLSV-GDPWRQCEALQ- 1432
Query: 1544 CSK--NNGGCSPYATCKS---------TGDGQRTCT-------------------CDTAH 1573
C + NN C P + + G +RTC C+T
Sbjct: 1433 CWRLFNNSRCDPACSSPACLYDNFDCHAGGRERTCNPVYEKYCADHFADGRCDQGCNTEE 1492
Query: 1574 TVGDGLTCRARVGLELLR 1591
DGL C + V L R
Sbjct: 1493 CGWDGLDCASEVPALLAR 1510
Score = 47.0 bits (110), Expect = 2e-04
Identities = 41/144 (28%), Positives = 55/144 (38%), Gaps = 13/144 (9%)
Query: 215 PSCRCLPGYTQQGSECRAPNPCWP-SPCSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPK 273
P R LP A PC SPC+ +C+ P +A C CP + G+ C +
Sbjct: 22 PPVRALPLLLLLAGPGAAAPPCLDGSPCANGGRCTQLPSREAACLCPPGWVGER--CQLE 79
Query: 274 DPCTDNLGGCPSNSTL--CVYQKPGQAFCTCRPGLVSINSNASAGCFAFCSPFSCDRSAT 331
DPC + G C V + C C G + + C + SP C A
Sbjct: 80 DPC--HSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCLS--SP--CAHGAR 133
Query: 332 CQVTADGKTSCVCRESEVGDGRAC 355
C V DG+ C C GR+C
Sbjct: 134 CSVGPDGRFLCSCPPGY--QGRSC 155
Score = 42.7 bits (99), Expect = 0.005
Identities = 64/274 (23%), Positives = 83/274 (30%), Gaps = 82/274 (29%)
Query: 1236 GPMLEAPGRSLIGLSGVLTVGSSRCL--HSHAEALREKCVNCTRRFRCTQGFQ---LQDT 1290
GP L++ R L + V VG RC + E +N R C LQD
Sbjct: 1167 GPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDP 1226
Query: 1291 PRK-SCVYRSGFSFSRGCSYTCAKKIQVPDCCPGFFGTLCEPCPGGLGGVCSGHGQCQDR 1349
C+ +GFS R C + + P G C P PG GG+
Sbjct: 1227 GGGFRCLCHAGFSGPR-----CQTVLSPCESQPCQHGGQCRPSPGPGGGL---------- 1271
Query: 1350 FLGSGECHCHEGFHGTACE--------------------------VCELGRYGPNCTGV- 1382
+ CHC + F G CE C G GP+C
Sbjct: 1272 ---TFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFP 1328
Query: 1383 --------CDCAHGLCQEG-------LQGDGSCVCNVGWQGLRCDQKITSPQ------CP 1421
CA C G L C C GW G RC+ +P+ CP
Sbjct: 1329 GSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCP 1388
Query: 1422 R----------KCDPNANCVQDSAGASTCACAAG 1445
R +CD N C+ + G
Sbjct: 1389 RAACQAKRGDQRCDRECNSPGCGWDGGDCSLSVG 1422
>gi|66346695 fibrillin 2 precursor [Homo sapiens]
Length = 2912
Score = 108 bits (269), Expect = 9e-23
Identities = 89/331 (26%), Positives = 137/331 (41%), Gaps = 52/331 (15%)
Query: 1271 KCVNCTRRFRCTQGFQLQDTP-RKSCV-YRSGFSFSRGCSYTCAKKIQVPDC-CPGFFGT 1327
KCVN ++C+ Q TP R+ C + GC C +C C +
Sbjct: 1215 KCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYAL 1274
Query: 1328 L-----------CEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHG-----TACEVCE 1371
+ CE P +C G GQC + G C C++GF T +V E
Sbjct: 1275 MPDGRSCADIDECENNPD----ICDG-GQCTN-IPGEYRCLCYDGFMASMDMKTCIDVNE 1328
Query: 1372 LGRYGPNCTGVCDCAHGLCQ----EGLQGDGSCVCNVGWQGLRCDQKITS-PQCP---RK 1423
CD +C E +G C C +G+ + T +C
Sbjct: 1329 -----------CDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHN 1377
Query: 1424 CDPNANCVQDSAGASTCACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCT 1483
CD +A+C+ + G+ C+C G+ GNGI C ++D C++G CS +A C PG C
Sbjct: 1378 CDMHASCL-NIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVN-TPGSYRCA 1435
Query: 1484 CQDGYMGDGELCQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGYS-GDGIRTCELLD 1542
C +G+ GDG C +++ C + C + +C+ P C C G++ R+C+ +D
Sbjct: 1436 CSEGFTGDGFTCSDVDECAENINLCE-NGQCLNV-PGAYRCECEMGFTPASDSRSCQDID 1493
Query: 1543 PCSKNNGGCSPYATCKSTGDGQRTCTCDTAH 1573
CS N + TC + G C CD +
Sbjct: 1494 ECSFQN--ICVFGTCNNL-PGMFHCICDDGY 1521
Score = 92.0 bits (227), Expect = 7e-18
Identities = 89/340 (26%), Positives = 125/340 (36%), Gaps = 79/340 (23%)
Query: 712 NQTIMEQGCCKGFFGPDCTQCPGGFS-----NPCYGKGNCS--DGIQGNGACL------- 757
N + G C G CP G C CS D + NG C+
Sbjct: 1165 NPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQ 1224
Query: 758 --CFPDYKGIACHICSNPNKHGEQCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFS---- 811
C P Y+ + P++ G ++C ++G CD + + + +C+ G++
Sbjct: 1225 CSCNPGYQ-------ATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPD 1277
Query: 812 GRFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEG--DGFSCTPSNPCS--- 866
GR C + + +C C +C + G RC C DGF D +C N C
Sbjct: 1278 GRSCAD-IDECENN--PDICD-GGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNS 1333
Query: 867 -----------------HPDRG--------GCSENAECVPGSL------------GTHHC 889
H G GC++ EC G+ G+ C
Sbjct: 1334 NICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKC 1393
Query: 890 TCHKGWSGDGRVCVAIDECELDMRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPID 949
+C +GW G+G C+ +DEC C +A C PG RC C GF GDG+ CS +D
Sbjct: 1394 SCREGWIGNGIKCIDLDECSNGTHQ-CSINAQCVNT-PGSYRCACSEGFTGDGFTCSDVD 1451
Query: 950 PCRAGNGGCHGLATCRAVGGGQRVCTCPPGF--GGDGFSC 987
C C C V G R C C GF D SC
Sbjct: 1452 ECAENINLCEN-GQCLNVPGAYR-CECEMGFTPASDSRSC 1489
Score = 89.0 bits (219), Expect = 6e-17
Identities = 91/336 (27%), Positives = 130/336 (38%), Gaps = 78/336 (23%)
Query: 702 VLKKGCASYCNQT--IMEQGCCKGFF----GPDCTQCPGGFSNPCYGKGNCSDGIQGNGA 755
++ GC + C + E C +G+ G C +NP G I G
Sbjct: 1248 IMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYR 1307
Query: 756 CLCFPDYKGIA----------CHICSNPNKHGE----------QCQ-------------- 781
CLC+ + C + SN GE CQ
Sbjct: 1308 CLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTD 1367
Query: 782 -EDC-----GC-VHGLCDNRPGSGGV-CQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHL 833
++C C +H C N PGS C++G G C + + +C G Q C +
Sbjct: 1368 VDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIK---CID-LDECS-NGTHQ-CSI 1421
Query: 834 HARCVSQEGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAEC--VPGSLGTHHCTC 891
+A+CV+ G RC C +GF GDGF+C+ + C+ + EN +C VPG+ + C C
Sbjct: 1422 NAQCVNTPGSYRCACSEGFTGDGFTCSDVDECA--ENINLCENGQCLNVPGA---YRCEC 1476
Query: 892 HKGW--SGDGRVCVAIDECELD---MRGGCHTDALCSYVGPGQSRCTCKLGFAGD--GYQ 944
G+ + D R C IDEC + G C+ PG C C G+ D G
Sbjct: 1477 EMGFTPASDSRSCQDIDECSFQNICVFGTCNN-------LPGMFHCICDDGYELDRTGGN 1529
Query: 945 CSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGF 980
C+ ID C +GL G+ C CPP F
Sbjct: 1530 CTDIDECADPINCVNGLCVNTP---GRYECNCPPDF 1562
Score = 78.6 bits (192), Expect = 8e-14
Identities = 82/333 (24%), Positives = 123/333 (36%), Gaps = 39/333 (11%)
Query: 32 CDVKTTFVTHVPCTSCAAIKKQTCPSGWLRELPDQITQDCRYEVQLGGSMVSMSGCRRKC 91
C + + C + + +C G+ Q T D + + M+ GC +C
Sbjct: 1204 CSLSDNLCRNGKCVNMIGTYQCSCNPGY------QATPDRQGCTDIDECMIMNGGCDTQC 1257
Query: 92 RKQV--VQKACCPGYW----GSRC---HECPGGAETPCNGHGTCLDGMDRNGTCVCQENF 142
+ +C GY G C EC + G T + G R C+C + F
Sbjct: 1258 TNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYR---CLCYDGF 1314
Query: 143 RGSA-CQECQDPNRFGPDCQSVCS-CVHGVCNHGPRGDGSCLCFAGYT---GPHCDQELP 197
S + C D N +C + C+ G C + +G C C GY+ G ++
Sbjct: 1315 MASMDMKTCIDVN----ECDLNSNICMFGECEN-TKGSFICHCQLGYSVKKGTTGCTDVD 1369
Query: 198 VCQ--ELRCPQNTQCSAEAPS--CRCLPGYTQQGSECRAPNPC--WPSPCSLLAQCSVSP 251
C+ C + C S C C G+ G +C + C CS+ AQC +P
Sbjct: 1370 ECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTP 1429
Query: 252 KGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPGLVSINS 311
G +C C E + GDG C D C +N+ C + L V PG C C G +
Sbjct: 1430 -GSYRCACSEGFTGDGFTCSDVDECAENINLCENGQCLNV---PGAYRCECEMGFTPASD 1485
Query: 312 NASAGCFAFCSPFSCDRSATCQVTADGKTSCVC 344
+ S CS + TC G C+C
Sbjct: 1486 SRSCQDIDECSFQNICVFGTCN-NLPGMFHCIC 1517
Score = 77.8 bits (190), Expect = 1e-13
Identities = 95/388 (24%), Positives = 146/388 (37%), Gaps = 82/388 (21%)
Query: 1244 RSLIGLSGVLTVGSSRCLHSHAEALREKCVNCTRRFRCT--QGFQLQDTPRKSCVYRSGF 1301
R L + GV + C +CVN F C +G L T R R
Sbjct: 943 RGLARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQ 1002
Query: 1302 SFSRG----CSYTCAKKIQVPDCCPGF---FGTLCEPCPG------------GLG----- 1337
+ + C + K ++ CC +GT CE CP G G
Sbjct: 1003 CYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRG 1062
Query: 1338 -------------------GVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPN 1378
G+C+ +G+C++ +GS +C C+ GF L N
Sbjct: 1063 DVLTGRPFYKDINECKAFPGMCT-YGKCRNT-IGSFKCRCNSGF--------ALDMEERN 1112
Query: 1379 CTGVCDC--AHGLCQEGL----QGDGSCVCNVGWQG--LRCDQKITSPQCPRK---CDPN 1427
CT + +C + LC G+ G C C G++ + + +C R C
Sbjct: 1113 CTDIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCR-G 1171
Query: 1428 ANCVQDSAGASTCACAAGY--SGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQ 1485
CV ++ G+ C C G+ S + C +++ C+ C + C + G C+C
Sbjct: 1172 GTCV-NTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCR-NGKCVNMI-GTYQCSCN 1228
Query: 1486 DGYMG--DGELCQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGYS--GDGIRTCELL 1541
GY D + C +I+ C+I +GGC +C CSC EGY+ DG R+C +
Sbjct: 1229 PGYQATPDRQGCTDIDECMIMNGGC--DTQC-TNSEGSYECSCSEGYALMPDG-RSCADI 1284
Query: 1542 DPCSKNNGGCSPYATCKSTGDGQRTCTC 1569
D C N C C + G+ C C
Sbjct: 1285 DECENNPDICDG-GQCTNI-PGEYRCLC 1310
Score = 71.6 bits (174), Expect = 9e-12
Identities = 78/296 (26%), Positives = 107/296 (36%), Gaps = 44/296 (14%)
Query: 1271 KCVNCTRRFRC--TQGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKKIQVPD-------CC 1321
+CVN +RC +GFQ + + R G F+ C + CC
Sbjct: 2353 RCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCC 2412
Query: 1322 PGF--FGTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNC 1379
G +G CE CP L G C G + +G C+V PN
Sbjct: 2413 DGGRGWGHQCELCP--LPGTAQYKKICPH-----GPGYTTDGRDIDECKVM------PNL 2459
Query: 1380 TGVCDCAHGLCQEGLQGDGSCVCNVGW----QGLRCDQKITSPQCPRKCDPNANCVQDSA 1435
C +G C + G C C VG+ G C Q P+ C N C +++
Sbjct: 2460 -----CTNGQCINTM-GSFRCFCKVGYTTDISGTSCIDLDECSQSPKPC--NYIC-KNTE 2510
Query: 1436 GASTCACAAGY--SGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGE 1493
G+ C+C GY +G C ++D C C C G TC C G+
Sbjct: 2511 GSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQ--FLCVNTLGGF-TCKCPPGFTQHHT 2567
Query: 1494 LCQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGI-RTCELLDPCSKNN 1548
C + N C C C T P SC C+ G+S D CE +D C N+
Sbjct: 2568 ACIDNNECGSQPSLCGAKGICQNT-PGSFSCECQRGFSLDATGLNCEDVDECDGNH 2622
Score = 71.2 bits (173), Expect = 1e-11
Identities = 96/386 (24%), Positives = 138/386 (35%), Gaps = 99/386 (25%)
Query: 664 GSCVDCQALNTSTCPPNSVK-------LDIFPKECVYIHDPTGLNVLKKGCASYCNQTIM 716
G+C + T CPP ++ +D+ C ++ T C + +
Sbjct: 1706 GTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTT-------CENELPFNVT 1758
Query: 717 EQGCCKGFFGPDCTQCPGGFSN----PCYGKGNCS-DGIQGNGACLCFPDYKGIACHICS 771
++ CC CT G N PC G I GN F + G A I
Sbjct: 1759 KRMCC-------CTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDI-- 1809
Query: 772 NPNKHGEQCQEDCG-CVHGLCDNRPGSGGVCQQGTCAPGFSGR---FCNESMGDCGPTGL 827
++C+E G C +G+C N+ GS C+ C GFS E + +C
Sbjct: 1810 ------DECKEIPGICANGVCINQIGSFR-CE---CPTGFSYNDLLLVCEDIDECSNGD- 1858
Query: 828 AQHCHLHARCVSQEGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSL--- 884
C +A C++ G RC C GF +P+ C DR C E L
Sbjct: 1859 -NLCQRNADCINSPGSYRCEC-----AAGFKLSPNGAC--VDRNECLEIPNVCSHGLCVD 1910
Query: 885 --GTHHCTCHKGW--SGDGRVCVAIDECELDMRGG-------------CH---------- 917
G++ C CH G+ S D +C+ +DECE G C+
Sbjct: 1911 LQGSYQCICHNGFKASQDQTMCMDVDECERHPCGNGTCKNTVGSYNCLCYPGFELTHNND 1970
Query: 918 ---TDALCSYVGP-----------GQSRCTCKLGF--AGDGYQCSPIDPCRAGNGGCHGL 961
D S+ G G +C C G+ DG C + C A G C
Sbjct: 1971 CLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSC-SP 2029
Query: 962 ATCRAVGGGQRVCTCPPGFGGDGFSC 987
TC+ + G R C CPPG+ +C
Sbjct: 2030 GTCQNLEGSFR-CICPPGYEVKSENC 2054
Score = 70.9 bits (172), Expect = 2e-11
Identities = 80/316 (25%), Positives = 114/316 (36%), Gaps = 45/316 (14%)
Query: 700 LNVLKKGCASYCNQTIMEQGCCKGF--FGPDCTQCP----GGFSNPC-YGKGNCSDG--- 749
L + + +S N + CC G +G C CP + C +G G +DG
Sbjct: 2391 LQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDI 2450
Query: 750 --------IQGNGACLCFPDYKGIACHICSNPNKHGEQCQEDCGCVHG------LCDNRP 795
+ NG C+ C + + G C + C +C N
Sbjct: 2451 DECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTE 2510
Query: 796 GSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGD 855
GS Q +C G+ + ++ D QH + CV+ G C+C GF
Sbjct: 2511 GS----YQCSCPRGYVLQEDGKTCKDLDECQTKQH-NCQFLCVNTLGGFTCKCPPGFTQH 2565
Query: 856 GFSCTPSNPC-SHPDRGGCSENAECVPGSLGTHHCTCHKGWSGD--GRVCVAIDECELDM 912
+C +N C S P G + PGS C C +G+S D G C +DEC+ +
Sbjct: 2566 HTACIDNNECGSQPSLCGAKGICQNTPGSFS---CECQRGFSLDATGLNCEDVDECDGNH 2622
Query: 913 R--GGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRAVGGG 970
R GC G RC C G+ +D N G A+C G
Sbjct: 2623 RCQHGCQNIL-------GGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSASCYNTLGS 2675
Query: 971 QRVCTCPPGFGGDGFS 986
+ C CP GF D FS
Sbjct: 2676 YK-CACPSGFSFDQFS 2690
Score = 70.5 bits (171), Expect = 2e-11
Identities = 87/327 (26%), Positives = 115/327 (35%), Gaps = 74/327 (22%)
Query: 1272 CVNCTRRFRCT--QGFQLQDTPRKSCVYRSGFSFSR----GCSYTCAKKIQVPDCC---- 1321
C N F+C GF L D R+ R F F+ CS A CC
Sbjct: 2072 CTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKM 2131
Query: 1322 PGF-FGTLCEPCPG------------GLG-------------------GVCSGHGQCQDR 1349
PG +G CE CP G G G+CS +GQC +
Sbjct: 2132 PGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICS-NGQCINT 2190
Query: 1350 FLGSGECHCHEGFH----GTAC---EVCELGRYGPNCTGVCDCAHGLCQEGLQGDGSCVC 1402
GS C C G++ G C + C +G C +G C + G C C
Sbjct: 2191 D-GSFRCECPMGYNLDYTGVRCVDTDECSIGN---------PCGNGTCTNVI-GSFECNC 2239
Query: 1403 NVGWQG---LRCDQKITSPQCPRKCDPNANCVQDSAGASTCACAAGYS--GNGIFCSEVD 1457
N G++ + C+ Q P C A ++ G+ C C GY+ + C ++D
Sbjct: 2240 NEGFEPGPMMNCEDINECAQNPLLC---AFRCMNTFGSYECTCPIGYALREDQKMCKDLD 2296
Query: 1458 PCAHGHGGCSPHANCTKVAPGQRTCTCQDGY--MGDGELCQEINSCLIHHGGCHIHAECI 1515
CA G C K G C C G DGE C + N C G C + C+
Sbjct: 2297 ECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGICE-NGRCV 2355
Query: 1516 PTGPQQVSCSCREGYSGDGIRTCELLD 1542
C C EG+ T E LD
Sbjct: 2356 NI-IGSYRCECNEGFQSSSSGT-ECLD 2380
Score = 68.2 bits (165), Expect = 1e-10
Identities = 65/257 (25%), Positives = 103/257 (40%), Gaps = 26/257 (10%)
Query: 1330 EPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCTGVCDCAHGL 1389
+ C G +C + C + GS C C GF + C VC +HGL
Sbjct: 1852 DECSNG-DNLCQRNADCINS-PGSYRCECAAGFKLSPNGACVDRNECLEIPNVC--SHGL 1907
Query: 1390 CQEGLQGDGSCVCNVGWQGLRCDQKITSP--QCPRKCDPNANCVQDSAGASTCACAAGYS 1447
C + LQG C+C+ G++ + DQ + +C R N C +++ G+ C C G+
Sbjct: 1908 CVD-LQGSYQCICHNGFKASQ-DQTMCMDVDECERHPCGNGTC-KNTVGSYNCLCYPGFE 1964
Query: 1448 -GNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGY--MGDGELCQEINSCLIH 1504
+ C ++D C+ G + C G C C +GY DG+ C + N C+
Sbjct: 1965 LTHNNDCLDIDECSSFFGQVCRNGRCFNEI-GSFKCLCNEGYELTPDGKNCIDTNECVAL 2023
Query: 1505 HGGCHIHAECIPTGPQQVS----CSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKST 1560
G C P Q + C C GY C ++ C ++ C + +C +T
Sbjct: 2024 PGSCS------PGTCQNLEGSFRCICPPGYEVKS-ENCIDINECDEDPNICL-FGSCTNT 2075
Query: 1561 GDGQRTCTCDTAHTVGD 1577
G + C C + D
Sbjct: 2076 PGGFQ-CLCPPGFVLSD 2091
Score = 67.8 bits (164), Expect = 1e-10
Identities = 79/322 (24%), Positives = 117/322 (36%), Gaps = 52/322 (16%)
Query: 1272 CVNCTRRFRCT--QGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKKIQVPDCCPGFFGTLC 1329
C+N F+C QG+ L + R F+ C P C G
Sbjct: 1666 CINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCG---------PGTCYNTLGNYT 1716
Query: 1330 EPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCTG-VCDCAHG 1388
CP V GH C D + C+ ++GT CE N T +C C +
Sbjct: 1717 CICPPEYMQVNGGHN-CMDM----RKSFCYRSYNGTTCE----NELPFNVTKRMCCCTYN 1767
Query: 1389 L----------CQEGLQGDGSCVCNVGWQGLRCD----QKITSPQC---PRKCDPNANCV 1431
+ C D +C G D + + +C P C N C+
Sbjct: 1768 VGKAWNKPCEPCPTPGTADFKTICG-NIPGFTFDIHTGKAVDIDECKEIPGIC-ANGVCI 1825
Query: 1432 QDSAGASTCACAAGYSGNGIF--CSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGY- 1488
+ G+ C C G+S N + C ++D C++G C +A+C +PG C C G+
Sbjct: 1826 -NQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCIN-SPGSYRCECAAGFK 1883
Query: 1489 MGDGELCQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRT-CELLDPCSKN 1547
+ C + N CL C H C+ C C G+ +T C +D C ++
Sbjct: 1884 LSPNGACVDRNECLEIPNVCS-HGLCVDL-QGSYQCICHNGFKASQDQTMCMDVDECERH 1941
Query: 1548 NGGCSPYATCKSTGDGQRTCTC 1569
G TCK+T G C C
Sbjct: 1942 PCG---NGTCKNT-VGSYNCLC 1959
Score = 67.4 bits (163), Expect = 2e-10
Identities = 75/312 (24%), Positives = 113/312 (36%), Gaps = 71/312 (22%)
Query: 717 EQGCCKGFFGPDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKH 776
+Q CK D +C G + C +G + G C+C P + P+
Sbjct: 2288 DQKMCK-----DLDECAEGLHD-CESRGMMCKNLIGTFMCICPPG-------MARRPDGE 2334
Query: 777 GEQCQEDCGCVHGLCDNRPGSGGVC------QQGTCAPGF----SGRFCNES-MGDCGPT 825
G + +C G+C+N G C + C GF SG C ++ G C
Sbjct: 2335 GCVDENECRTKPGICEN-----GRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAE 2389
Query: 826 GLAQHCHLHARCVSQEGVARCRCLDGFEGDGFSCT--------------PSNPCSHPDRG 871
L C + + + + C C DG G G C P P D
Sbjct: 2390 VLQTICQMASSSRNLVTKSEC-CCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGR 2448
Query: 872 GCSE---------NAECVPGSLGTHHCTCHKGWSGD--GRVCVAIDECELDMRGGCHTDA 920
E N +C+ ++G+ C C G++ D G C+ +DEC +
Sbjct: 2449 DIDECKVMPNLCTNGQCI-NTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKP------ 2501
Query: 921 LCSYV---GPGQSRCTCKLGFA--GDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCT 975
C+Y+ G +C+C G+ DG C +D C+ C L +GG C
Sbjct: 2502 -CNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCV-NTLGGF--TCK 2557
Query: 976 CPPGFGGDGFSC 987
CPPGF +C
Sbjct: 2558 CPPGFTQHHTAC 2569
Score = 66.6 bits (161), Expect = 3e-10
Identities = 65/253 (25%), Positives = 94/253 (37%), Gaps = 29/253 (11%)
Query: 1945 GCHRNCVTT--TWKPSCCPGHY----GSEC---QACPGGPSSPCSDRGVCMDGMSGSGQC 1995
GC C + +++ SC G+ G C C P D G C + + G +C
Sbjct: 1252 GCDTQCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPD--ICDGGQCTN-IPGEYRC 1308
Query: 1996 LCRSGF-AGTACELCAP-GAFGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWT---GPRC 2050
LC GF A + C + C + G C E GS C C G++ G
Sbjct: 1309 LCYDGFMASMDMKTCIDVNECDLNSNIC---MFGEC-ENTKGSFICHCQLGYSVKKGTTG 1364
Query: 2051 EVQLELQPVCTPPCAPEAVCR---AGNSCECSLGYEGDGRVCTVADLCQDGHGGCSEHAN 2107
++ + C A C C C G+ G+G C D C +G CS +A
Sbjct: 1365 CTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQ 1424
Query: 2108 CSQVGTMVTCTCLPDYEGDGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGY- 2166
C C C + GDG++C + C + E+ CL+ RCEC G+
Sbjct: 1425 CVNTPGSYRCACSEGFTGDGFTCSDVDECAENI--NLCENGQCLNVP-GAYRCECEMGFT 1481
Query: 2167 -VGDGLQCLEESE 2178
D C + E
Sbjct: 1482 PASDSRSCQDIDE 1494
Score = 66.6 bits (161), Expect = 3e-10
Identities = 72/278 (25%), Positives = 106/278 (38%), Gaps = 42/278 (15%)
Query: 97 QKACCPGYWGSRCHECPGGAETPCNG----------------HGTCLDGMDRNGTCVCQE 140
+ A C GS EC G + NG HG C+D + + C+C
Sbjct: 1863 RNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVCSHGLCVD-LQGSYQCICHN 1921
Query: 141 NFRGSACQE-CQDPNRFGPDCQSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQELPV- 198
F+ S Q C D + +C+ C +G C + G +CLC+ G+ H + L +
Sbjct: 1922 GFKASQDQTMCMDVD----ECERH-PCGNGTCKNTV-GSYNCLCYPGFELTHNNDCLDID 1975
Query: 199 -CQEL--RCPQNTQCSAEAPSCRCL--PGY--TQQGSECRAPNPCWPSPCSLLAQCSVSP 251
C + +N +C E S +CL GY T G C N C P S +
Sbjct: 1976 ECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNL 2035
Query: 252 KGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPGLVSINS 311
+G +C CP Y C+ + C ++ C S PG C C PG V S
Sbjct: 2036 EGSFRCICPPGYEVKSENCIDINECDEDPNICLFGSCT---NTPGGFQCLCPPGFVL--S 2090
Query: 312 NASAGCF----AFC-SPFSCDRSATCQVTADGKTSCVC 344
+ CF +FC + F + + + K C C
Sbjct: 2091 DNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCC 2128
Score = 64.7 bits (156), Expect = 1e-09
Identities = 80/295 (27%), Positives = 108/295 (36%), Gaps = 58/295 (19%)
Query: 716 MEQGCCK--GFFGPDCTQCPGG----FSNPC---YGKGNCSDGIQGNGACLCFPDYKGIA 766
M+ CC +G +C +CP + C G N D + G P YK I
Sbjct: 1022 MDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGR------PFYKDI- 1074
Query: 767 CHICSNPNKHGEQCQEDCG-CVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPT 825
+C+ G C +G C N GS C+ C GF+ + D
Sbjct: 1075 -----------NECKAFPGMCTYGKCRNTIGSFK-CR---CNSGFALDMEERNCTDIDEC 1119
Query: 826 GLAQHCHLHARCVSQEGVARCRCLDGFEGDGF----SCTPSNPCSHPD---RGGCSENAE 878
++ CV+ G C C +G+E GF +C + C RGG N E
Sbjct: 1120 RISPDLCGSGICVNTPGSFECECFEGYES-GFMMMKNCMDIDECERNPLLCRGGTCVNTE 1178
Query: 879 CVPGSLGTHHCTCHKGW--SGDGRVCVAIDECELDMRGGCHTDALCSYVGPGQSRCTCKL 936
G+ C C G S CV I+EC L C + +G Q C+C
Sbjct: 1179 ------GSFQCDCPLGHELSPSREDCVDINECSLS-DNLCRNGKCVNMIGTYQ--CSCNP 1229
Query: 937 GFAG--DGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGFG--GDGFSC 987
G+ D C+ ID C NGGC T G C+C G+ DG SC
Sbjct: 1230 GYQATPDRQGCTDIDECMIMNGGCDTQCT---NSEGSYECSCSEGYALMPDGRSC 1281
Score = 63.5 bits (153), Expect = 3e-09
Identities = 63/241 (26%), Positives = 97/241 (40%), Gaps = 47/241 (19%)
Query: 731 QCPGGF----SNPCYGKGNCSD--GIQGNGACLCFPDYKGIACHICSNPNKHGEQCQEDC 784
+C GF + C + C + + +G C+ D +G IC N K Q Q C
Sbjct: 1877 ECAAGFKLSPNGACVDRNECLEIPNVCSHGLCV---DLQGSYQCICHNGFK-ASQDQTMC 1932
Query: 785 GCVHGLCDNRPGSGGVCQQGT------CAPGFSGRFCNESMG--DCGPTGLAQHCHLHAR 836
V C+ P G C+ C PGF N+ + +C + Q C + R
Sbjct: 1933 MDVDE-CERHPCGNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECS-SFFGQVCR-NGR 1989
Query: 837 CVSQEGVARCRCLDGFE--GDGFSCTPSNPCSHPDRGGCSENAECVPGSL----GTHHCT 890
C ++ G +C C +G+E DG +C +N C + C PG+ G+ C
Sbjct: 1990 CFNEIGSFKCLCNEGYELTPDGKNCIDTNEC-------VALPGSCSPGTCQNLEGSFRCI 2042
Query: 891 CHKGWSGDGRVCVAIDECELD----MRGGCHTDALCSYVGPGQSRCTCKLGF--AGDGYQ 944
C G+ C+ I+EC+ D + G C PG +C C GF + +G +
Sbjct: 2043 CPPGYEVKSENCIDINECDEDPNICLFGSCTNT-------PGGFQCLCPPGFVLSDNGRR 2095
Query: 945 C 945
C
Sbjct: 2096 C 2096
Score = 63.2 bits (152), Expect = 3e-09
Identities = 60/211 (28%), Positives = 84/211 (39%), Gaps = 40/211 (18%)
Query: 800 VCQQGTCAPGFSGRFCNESM-------GDC-GPTGLAQHCHLHARCVSQEGVARCRCLDG 851
+C G C P S C +M GDC + + CV+ G C+C G
Sbjct: 504 LCLNGRCIPTVSSYRCECNMGYKQDANGDCIDVDECTSNPCTNGDCVNTPGSYYCKCHAG 563
Query: 852 FEGDGF--SCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGW--SGDGRVCVAIDE 907
F+ +C + C G +N CV + G+ C C+ G+ + DG+ CV DE
Sbjct: 564 FQRTPTKQACIDIDECI--QNGVLCKNGRCV-NTDGSFQCICNAGFELTTDGKNCVDHDE 620
Query: 908 C---ELDMRGGCHTDALCSYVGPGQSRCTCKLGF--AGDGYQCSPIDPCRAG----NGGC 958
C + + G C + G +C CK GF A +G C+ +D C+ NG C
Sbjct: 621 CTTTNMCLNGMCINE-------DGSFKCICKPGFVLAPNGRYCTDVDECQTPGICMNGHC 673
Query: 959 HGLATCRAVGGGQRVCTCPPGF--GGDGFSC 987
G C CPPG G DG C
Sbjct: 674 IN-------SEGSFRCDCPPGLAVGMDGRVC 697
Score = 63.2 bits (152), Expect = 3e-09
Identities = 68/267 (25%), Positives = 98/267 (36%), Gaps = 49/267 (18%)
Query: 728 DCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQCQEDCGCV 787
+C+Q P PC +G+ C C +G K ++CQ
Sbjct: 2494 ECSQSP----KPC---NYICKNTEGSYQCSC---PRGYVLQEDGKTCKDLDECQTKQHNC 2543
Query: 788 HGLCDNRPGSGGVCQQGTCAPGFSGRF--------CNESMGDCGPTGLAQHCHLHARCVS 839
LC N G G C+ C PGF+ C CG G+ C +
Sbjct: 2544 QFLCVNTLG-GFTCK---CPPGFTQHHTACIDNNECGSQPSLCGAKGI---------CQN 2590
Query: 840 QEGVARCRCLDGFEGD--GFSCTPSNPC--SHPDRGGCSENAECVPGSLGTHHCTCHKGW 895
G C C GF D G +C + C +H + GC LG + C C +G+
Sbjct: 2591 TPGSFSCECQRGFSLDATGLNCEDVDECDGNHRCQHGCQN-------ILGGYRCGCPQGY 2643
Query: 896 SGDGRVCVAIDECELDMRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQ--CSPIDPCRA 953
+ +DE E C + A C Y G +C C GF+ D + C ++ C +
Sbjct: 2644 IQHYQWNQCVDENECSNPNACGS-ASC-YNTLGSYKCACPSGFSFDQFSSACHDVNECSS 2701
Query: 954 GNGGCHGLATCRAVGGGQRVCTCPPGF 980
C+ C GG +C CPPG+
Sbjct: 2702 SKNPCN--YGCSNTEGGY-LCGCPPGY 2725
Score = 62.4 bits (150), Expect = 6e-09
Identities = 84/347 (24%), Positives = 125/347 (36%), Gaps = 57/347 (16%)
Query: 654 CSEEQHKIVAGSCVDCQALNTSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKG-CASYCN 712
C E+ + + GSC + CPP V D + C + G C+
Sbjct: 2060 CDEDPNICLFGSCTNTPGGFQCLCPPGFVLSD-NGRRCFDTRQSFCFTNFENGKCSVPKA 2118
Query: 713 QTIMEQGCCKGFFGPDCTQCPG-GFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICS 771
+ CC C++ PG G+ +PC LC D + +C
Sbjct: 2119 FNTTKAKCC-------CSKMPGEGWGDPCE---------------LCPKDDEVAFQDLC- 2155
Query: 772 NPNKHG------------EQCQEDCG-CVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNES 818
P HG +C E G C +G C N GS C+ C G++ +
Sbjct: 2156 -PYGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFR-CE---CPMGYNLDYTGVR 2210
Query: 819 MGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFE-GDGFSCTPSNPCSHPDRGGCSENA 877
D + C + C + G C C +GFE G +C N C+ +
Sbjct: 2211 CVDTDECSIGNPCG-NGTCTNVIGSFECNCNEGFEPGPMMNCEDINECA---QNPLLCAF 2266
Query: 878 ECVPGSLGTHHCTCHKGWS--GDGRVCVAIDECELDMRGGCHTDALCSYVGPGQSRCTCK 935
C+ + G++ CTC G++ D ++C +DEC + C + + G C C
Sbjct: 2267 RCM-NTFGSYECTCPIGYALREDQKMCKDLDECAEGLH-DCESRGMMCKNLIGTFMCICP 2324
Query: 936 LGFA--GDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGF 980
G A DG C + CR G C C + G R C C GF
Sbjct: 2325 PGMARRPDGEGCVDENECRTKPGICEN-GRCVNIIGSYR-CECNEGF 2369
Score = 62.0 bits (149), Expect = 7e-09
Identities = 68/263 (25%), Positives = 105/263 (39%), Gaps = 34/263 (12%)
Query: 1249 LSGVLTVGSSRCLHSHAEALREKCVNCTRRFRCT--QGFQLQDTPRKSCVYRSGFSFSRG 1306
+SG + C S + C N ++C+ +G+ LQ+ + +
Sbjct: 2484 ISGTSCIDLDECSQS-PKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHN 2542
Query: 1307 CSYTCAKKIQ--VPDCCPGF--FGTLC---EPCPGGLGGVCSGHGQCQDRFLGSGECHCH 1359
C + C + C PGF T C C G +C G CQ+ GS C C
Sbjct: 2543 CQFLCVNTLGGFTCKCPPGFTQHHTACIDNNEC-GSQPSLCGAKGICQNT-PGSFSCECQ 2600
Query: 1360 EGFHGTACEVCELGRYGPNCTGVCDC-AHGLCQEGLQ---GDGSCVCNVGW-QGLRCDQK 1414
GF L G NC V +C + CQ G Q G C C G+ Q + +Q
Sbjct: 2601 RGF--------SLDATGLNCEDVDECDGNHRCQHGCQNILGGYRCGCPQGYIQHYQWNQC 2652
Query: 1415 ITSPQC--PRKCDPNANCVQDSAGASTCACAAGYSGN--GIFCSEVDPCAHGHGGCSPHA 1470
+ +C P C +A+C ++ G+ CAC +G+S + C +V+ C+ C+
Sbjct: 2653 VDENECSNPNACG-SASCY-NTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCNYGC 2710
Query: 1471 NCTKVAPGQRTCTCQDGYMGDGE 1493
+ T+ G C C GY G+
Sbjct: 2711 SNTE---GGYLCGCPPGYYRVGQ 2730
Score = 59.7 bits (143), Expect = 4e-08
Identities = 92/366 (25%), Positives = 137/366 (37%), Gaps = 69/366 (18%)
Query: 1250 SGVLTVGSSRCLH-SHAEALREKCVNCTRRFRC--TQGFQLQDTPRKSCVYRSGFSFSRG 1306
+G+ + C + +H ++ +CVN +RC ++GF +G F+
Sbjct: 1402 NGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGF-------------TGDGFTCS 1448
Query: 1307 CSYTCAKKIQVPD---CC--PGFFGTLCEP--CPGGLGGVCSGHGQCQ-DRFLGSGECHC 1358
CA+ I + + C PG + CE P C +C G C+
Sbjct: 1449 DVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNICVFGTCNN 1508
Query: 1359 HEG-FHGTACEVCELGRYGPNCTGVCDCAHGL-CQEGL----QGDGSCVCNVGWQ----G 1408
G FH + EL R G NCT + +CA + C GL G C C +Q G
Sbjct: 1509 LPGMFHCICDDGYELDRTGGNCTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTG 1568
Query: 1409 LRC-DQKITSPQCPRKCDPNANCVQDSAGASTCACAAGYSGNGIFCSEVDPCAHGHGGCS 1467
+ C D ++ + C K P + G+ +C G + C C+ G +
Sbjct: 1569 VGCVDNRVGN--CYLKFGPRGD------GSLSCNTEIGVGVSRSSCC----CSLGKAWGN 1616
Query: 1468 PHANCTKVAPGQRTCTCQDG----------YMGDGELCQEINSCLIHHGGCHIHAECIPT 1517
P C V + C G + D + CQE+ + GG CI T
Sbjct: 1617 PCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPG--LCQGG-----NCINT 1669
Query: 1518 GPQQVSCSCREG-YSGDGIRTCELLDPCSKNNGGCSPYATCKSTGDGQRTCTCDTAH-TV 1575
C C +G Y + R CE +D C + G C P TC +T G TC C + V
Sbjct: 1670 F-GSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGP-GTCYNT-LGNYTCICPPEYMQV 1726
Query: 1576 GDGLTC 1581
G C
Sbjct: 1727 NGGHNC 1732
Score = 59.3 bits (142), Expect = 5e-08
Identities = 97/391 (24%), Positives = 138/391 (35%), Gaps = 90/391 (23%)
Query: 1252 VLTVGSSRCLHSHAEALR---EKCVN---CTRRFRCTQGFQLQDTPRKSCVYRSGFSFSR 1305
V T GS +C+ + L + CV+ CT C G + + C+ + GF +
Sbjct: 592 VNTDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAP 651
Query: 1306 GCSY-TCAKKIQVPDCCPGFF-----GTLCEPCPGGL-----GGVCSG------------ 1342
Y T + Q P C G+ CP GL G VC
Sbjct: 652 NGRYCTDVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIK 711
Query: 1343 HGQCQDRFLGS---GECHCHE---GFHGTACEVCELGRYGPNCTGVCDCAHGLCQEGLQG 1396
G C F G+ EC C GF G C+ C HGLC G+
Sbjct: 712 KGVCVRPFPGAVTKSECCCANPDYGF-GEPCQPCPAKNSAE--------FHGLCSSGV-- 760
Query: 1397 DGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCV-QDSAGASTCACAAGYS--GNGIFC 1453
G+ D + + +C D AN + ++ G+ C C +GY +G C
Sbjct: 761 -----------GITVDGRDIN-ECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNC 808
Query: 1454 SEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYM--GDGELCQEINSCLIH---HGGC 1508
++D C C + PG +CTC GY+ + E C++IN C + +G C
Sbjct: 809 IDIDECLVNRLLCDN--GLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNPCVNGAC 866
Query: 1509 H-----IHAECIPTGP-QQVSCSCREGYSGDGIRTCELL---DPCSKNNGGCSPYATCKS 1559
+ EC P C + G TC L C N G + + C +
Sbjct: 867 RNNLGSFNCECSPGSKLSSTGLICIDSLKG----TCWLNIQDSRCEVNINGATLKSECCA 922
Query: 1560 T-----GDGQRTCTCDTAHTVG----DGLTC 1581
T G C DTA G G+TC
Sbjct: 923 TLGAAWGSPCERCELDTACPRGLARIKGVTC 953
Score = 58.2 bits (139), Expect = 1e-07
Identities = 89/373 (23%), Positives = 128/373 (34%), Gaps = 108/373 (28%)
Query: 18 AGFSFVRGQVLFKGCDVKTTFVTHVPCTSCAAIKKQTCPSGWLRELPDQITQDCRYEVQL 77
+GF ++ + C+ C + + CP G EL +DC V +
Sbjct: 1148 SGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLG--HELSPS-REDC---VDI 1201
Query: 78 GGSMVSMSGCRR-KCRKQV--VQKACCPGYWGS----------RCHECPGGAETPC-NGH 123
+S + CR KC + Q +C PGY + C GG +T C N
Sbjct: 1202 NECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSE 1261
Query: 124 GTCLDGMDRNGTCVCQENFR----GSAC---QECQDPNRFGPDCQSVCSCVHGVCNHGPR 176
G+ C C E + G +C EC++ PD C G C + P
Sbjct: 1262 GSY--------ECSCSEGYALMPDGRSCADIDECEN----NPDI-----CDGGQCTNIP- 1303
Query: 177 GDGSCLCFAGYTGP----------HCDQELPVCQELRCPQNTQCSAEAPSCRCLPGYT-Q 225
G+ CLC+ G+ CD +C C +NT+ S C C GY+ +
Sbjct: 1304 GEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGEC-ENTKGSF---ICHCQLGYSVK 1359
Query: 226 QGSE-CRAPNPC--WPSPCSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGG 282
+G+ C + C C + A C P G +C C E + G+G+ C+ D C
Sbjct: 1360 KGTTGCTDVDECEIGAHNCDMHASCLNIP-GSFKCSCREGWIGNGIKCIDLDEC------ 1412
Query: 283 CPSNSTLCVYQKPGQAFCTCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVTADGKTSC 342
SN T C +A C V G C
Sbjct: 1413 --SNGT-----------------------------------HQCSINAQC-VNTPGSYRC 1434
Query: 343 VCRESEVGDGRAC 355
C E GDG C
Sbjct: 1435 ACSEGFTGDGFTC 1447
Score = 57.4 bits (137), Expect = 2e-07
Identities = 80/313 (25%), Positives = 104/313 (33%), Gaps = 76/313 (24%)
Query: 1933 PSLWGRPQGLGRGCHRNCVTTTWKPSCCP--------GHYGSEC----QACPGGPSSPCS 1980
P + RP G G C T KP C G Y EC Q+ G +
Sbjct: 2325 PGMARRPDGEGCVDENECRT---KPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDN 2381
Query: 1981 DRGVCMD--------------GMSGSGQCLCRSGFA-GTACELCA-PGAF---------- 2014
+G+C + +C C G G CELC PG
Sbjct: 2382 RQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGP 2441
Query: 2015 -----GPHCQACR-----CTVHGRCDEGLGGSGSCFCDEGWT----GPRCEVQLELQPVC 2060
G C+ CT +G+C +G S CFC G+T G C ++L
Sbjct: 2442 GYTTDGRDIDECKVMPNLCT-NGQCINTMG-SFRCFCKVGYTTDISGTSC---IDLDECS 2496
Query: 2061 TPPCAPEAVCR---AGNSCECSLGY--EGDGRVCTVADLCQDGHGGCSEHANCSQVGTMV 2115
P +C+ C C GY + DG+ C D CQ C C
Sbjct: 2497 QSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNC--QFLCVNTLGGF 2554
Query: 2116 TCTCLPDYEGDGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGD--GLQC 2173
TC C P + +C N C C C +T + CEC G+ D GL C
Sbjct: 2555 TCKCPPGFTQHHTACIDNNEC-GSQPSLCGAKGICQNTP-GSFSCECQRGFSLDATGLNC 2612
Query: 2174 LEESEPPVDRCLG 2186
+ VD C G
Sbjct: 2613 ED-----VDECDG 2620
Score = 56.2 bits (134), Expect = 4e-07
Identities = 74/265 (27%), Positives = 98/265 (36%), Gaps = 62/265 (23%)
Query: 1307 CSYTCAKKIQVPD----CCPGFFGTLC-EP-CPGGLGGVCSGHGQCQDRFLGSGECHCHE 1360
CS C D C G+ GT C +P C G C G+C +G C C
Sbjct: 149 CSVRCMNGGTCADDHCQCQKGYIGTYCGQPVCENG----CQNGGRC----IGPNRCACVY 200
Query: 1361 GFHGTACEVCELGRYGPNCTGVCDCAHGLCQEGLQG----DGSCVCNVG--WQGLRCDQK 1414
GF G CE R GP T V + +CQ L G C +G W G C+
Sbjct: 201 GFTGPQCE--RDYRTGPCFTQV---NNQMCQGQLTGIVCTKTLCCATIGRAW-GHPCEMC 254
Query: 1415 ITSPQ-CPRKCDPN---------------------ANCVQDSAGASTCACAAGY--SGNG 1450
PQ C R PN NC+ ++ G+ C C AG+ S
Sbjct: 255 PAQPQPCRRGFIPNIRTGACQDVDECQAIPGICQGGNCI-NTVGSFECRCPAGHKQSETT 313
Query: 1451 IFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYM--GDGELC--QEINSCL--IH 1504
C ++D C+ G C C+ G C C GY+ DG C Q C +
Sbjct: 314 QKCEDIDECSIIPGICET-GECSNTV-GSYFCVCPRGYVTSTDGSRCIDQRTGMCFSGLV 371
Query: 1505 HGGCHIHAECIPTGPQQVSCSCREG 1529
+G C A+ +P ++ C C G
Sbjct: 372 NGRC---AQELPGRMTKMQCCCEPG 393
Score = 56.2 bits (134), Expect = 4e-07
Identities = 59/215 (27%), Positives = 79/215 (36%), Gaps = 35/215 (16%)
Query: 98 KACCPGY--WGSRCHECP--GGAETP--C-NGHGTCLDGMD-----------RNGTCVCQ 139
+ CC G WG +C CP G A+ C +G G DG D NG C+
Sbjct: 2409 ECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTNGQCINT 2468
Query: 140 ENFRGSACQECQDPNRFGPDCQSVCSCVHGV--CNH---GPRGDGSCLCFAGYT----GP 190
C+ + G C + C CN+ G C C GY G
Sbjct: 2469 MGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGK 2528
Query: 191 HCDQELPVCQELRCPQNTQC--SAEAPSCRCLPGYTQQGSECRAPNPC--WPSPCSLLAQ 246
C ++L CQ + C + +C+C PG+TQ + C N C PS C
Sbjct: 2529 TC-KDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLCGAKGI 2587
Query: 247 CSVSPKGQAQCHCPENYHGD--GMVCLPKDPCTDN 279
C +P G C C + D G+ C D C N
Sbjct: 2588 CQNTP-GSFSCECQRGFSLDATGLNCEDVDECDGN 2621
Score = 55.1 bits (131), Expect = 9e-07
Identities = 95/376 (25%), Positives = 136/376 (36%), Gaps = 77/376 (20%)
Query: 664 GSCVDCQALNTS---TCP-PNSVKLDIFPKECVYIHDPTGLNVLKKGCASYCNQTI--ME 717
G C + Q +NT C P LD CV + + N G C I E
Sbjct: 2180 GICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNGT---CTNVIGSFE 2236
Query: 718 QGCCKGFF-GP--DCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPN 774
C +GF GP +C NP C + G+ C C Y
Sbjct: 2237 CNCNEGFEPGPMMNCEDINECAQNPLLCAFRCMNTF-GSYECTCPIGYA---------LR 2286
Query: 775 KHGEQCQEDCGCVHGL--CDNRPGSGGVCQQ--GT----CAPGFSGRFCNESMGDCGPTG 826
+ + C++ C GL C++R G +C+ GT C PG + R E D
Sbjct: 2287 EDQKMCKDLDECAEGLHDCESR---GMMCKNLIGTFMCICPPGMARRPDGEGCVDENECR 2343
Query: 827 LAQHCHLHARCVSQEGVARCRCLDGFE--GDGFSCTPSN-------------PCSHPDRG 871
+ RCV+ G RC C +GF+ G C + + R
Sbjct: 2344 TKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRN 2403
Query: 872 GCSENAECVPGSLGTHH----------------CTCHKGWSGDGRVCVAIDECELDMRGG 915
+++ C G G H C G++ DGR IDEC++ M
Sbjct: 2404 LVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGR---DIDECKV-MPNL 2459
Query: 916 CHTDALCSYVGPGQSRCTCKLGFAGD--GYQCSPIDPCRAGNGGCHGLATCRAVGGGQRV 973
C T+ C G RC CK+G+ D G C +D C C+ + C+ G +
Sbjct: 2460 C-TNGQCINT-MGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNYI--CKNTEGSYQ- 2514
Query: 974 CTCPPGF--GGDGFSC 987
C+CP G+ DG +C
Sbjct: 2515 CSCPRGYVLQEDGKTC 2530
Score = 53.9 bits (128), Expect = 2e-06
Identities = 58/202 (28%), Positives = 85/202 (42%), Gaps = 35/202 (17%)
Query: 756 CLCFPDYKGIACHICSNPNKHGEQCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFC 815
C C YK A C + ++C + C +G C N PGS C+ C GF
Sbjct: 519 CECNMGYKQDANGDCIDV----DECTSN-PCTNGDCVNTPGSY-YCK---CHAGFQRTPT 569
Query: 816 NES---MGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFE--GDGFSCTPSNPCSHPDR 870
++ + +C G+ C + RCV+ +G +C C GFE DG +C + C+ +
Sbjct: 570 KQACIDIDECIQNGVL--CK-NGRCVNTDGSFQCICNAGFELTTDGKNCVDHDECTTTN- 625
Query: 871 GGCSENAECVPGSLGTHHCTCHKGW--SGDGRVCVAIDECE---LDMRGGCHTDALCSYV 925
N C+ G+ C C G+ + +GR C +DEC+ + M G C
Sbjct: 626 --MCLNGMCI-NEDGSFKCICKPGFVLAPNGRYCTDVDECQTPGICMNGHCIN------- 675
Query: 926 GPGQSRCTCKLGFA--GDGYQC 945
G RC C G A DG C
Sbjct: 676 SEGSFRCDCPPGLAVGMDGRVC 697
Score = 53.9 bits (128), Expect = 2e-06
Identities = 92/381 (24%), Positives = 123/381 (32%), Gaps = 120/381 (31%)
Query: 697 PTGLNVLKKGCASYCNQTIMEQGCCKGFFGPDCTQCPGGFS----------------NPC 740
P G V + C N + G C G C GF +PC
Sbjct: 1886 PNGACVDRNECLEIPN--VCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECERHPC 1943
Query: 741 YGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQCQEDCG--CVHGLCDNRPGSG 798
G G C + + G+ CLC+P ++ + C + ++C G C +G C N GS
Sbjct: 1944 -GNGTCKNTV-GSYNCLCYPGFELTHNNDCLDI----DECSSFFGQVCRNGRCFNEIGSF 1997
Query: 799 G-VCQQG-TCAPGFSGRFC---NESM---GDCGPTGLAQHCHLHARCVSQEGVARCRCLD 850
+C +G P G+ C NE + G C P C + EG RC C
Sbjct: 1998 KCLCNEGYELTP--DGKNCIDTNECVALPGSCSP----------GTCQNLEGSFRCICPP 2045
Query: 851 GFEGDGFSCTPSNPCSHPDR----GGCS-------------------------------- 874
G+E +C N C G C+
Sbjct: 2046 GYEVKSENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCF 2105
Query: 875 ---ENAEC-VPGSLGT--HHCTCHK----GWSGDGRVCVAIDECEL-------------- 910
EN +C VP + T C C K GW +C DE
Sbjct: 2106 TNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSL 2165
Query: 911 -----DMRGGCHTDALCS----YVGPGQSRCTCKLGFAGD--GYQCSPIDPCRAGNGGCH 959
D+ + +CS G RC C +G+ D G +C D C GN C
Sbjct: 2166 HDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGN-PC- 2223
Query: 960 GLATCRAVGGGQRVCTCPPGF 980
G TC V G C C GF
Sbjct: 2224 GNGTCTNVIGSFE-CNCNEGF 2243
Score = 53.5 bits (127), Expect = 3e-06
Identities = 95/411 (23%), Positives = 142/411 (34%), Gaps = 91/411 (22%)
Query: 1966 SECQACPGGPSSPCSDRGVCMDGMSGSGQCLCRSGFA---------------------GT 2004
+EC+A PG G C + + GS +C C SGFA G+
Sbjct: 1075 NECKAFPG-----MCTYGKCRNTI-GSFKCRCNSGFALDMEERNCTDIDECRISPDLCGS 1128
Query: 2005 ACELCAPGAFGPHC---------QACRCTVHGRCDEG--LGGSGSCFCDEGWTGPRCEVQ 2053
+ PG+F C C C+ L G+C EG C +
Sbjct: 1129 GICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLG 1188
Query: 2054 LELQP-----VCTPPCA-PEAVCRAGN--------SCECSLGYEG--DGRVCTVADLCQD 2097
EL P V C+ + +CR G C C+ GY+ D + CT D C
Sbjct: 1189 HELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMI 1248
Query: 2098 GHGGCSEHANCSQVGTMVTCTCLPDYE--GDGWSCRARNPCTDGHRGGCSEHANCLSTGL 2155
+GGC C+ C+C Y DG SC + C + + C +
Sbjct: 1249 MNGGCD--TQCTNSEGSYECSCSEGYALMPDGRSCADIDECE--NNPDICDGGQCTNIP- 1303
Query: 2156 NTRRCECHAGYVG--DGLQCLEESEPPVDRCLGQPPPCHSDAMCTDLHFQEKRAGVFHLQ 2213
RC C+ G++ D C++ +E ++ + C + H Q G +
Sbjct: 1304 GEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQ---LGYSVKK 1360
Query: 2214 ATSGPYGLNFSEAEA-ACEAQGAVLASFPQLSAAQQLGFHLCLMGWLANGSTAHPVVFPV 2272
T+G ++ E A C+ + L + C GW+ NG +
Sbjct: 1361 GTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCS-------CREGWIGNGIKC----IDL 1409
Query: 2273 ADCGNGRVGIVSLGARKNLSERWDAYCFRVQ-DVACRCRNGFVGDGISTCN 2322
+C NG S+ A+ C C C GF GDG TC+
Sbjct: 1410 DECSNG-THQCSINAQ----------CVNTPGSYRCACSEGFTGDGF-TCS 1448
Score = 53.5 bits (127), Expect = 3e-06
Identities = 75/330 (22%), Positives = 104/330 (31%), Gaps = 83/330 (25%)
Query: 98 KACC---PGY-WGSRCHECPGGAETPCN-----GHGT-------------CLD--GMDRN 133
K CC PG WG C CP E GHGT CL+ G+ N
Sbjct: 2125 KCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSN 2184
Query: 134 GTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHGVCNHG-PRGDGSCLCFAGYTGPHC 192
G C+ N GS EC P + D V C+ G P G+G+C G +C
Sbjct: 2185 GQCI---NTDGSFRCEC--PMGYNLDYTGVRCVDTDECSIGNPCGNGTCTNVIGSFECNC 2239
Query: 193 DQELPVCQELRCPQNTQCSAEAPSC--RCLPGYTQQGSECRAPNPCWPSPCSLLAQCSVS 250
++ + C +C+ C RC+ +
Sbjct: 2240 NEGFEPGPMMNCEDINECAQNPLLCAFRCMNTF--------------------------- 2272
Query: 251 PKGQAQCHCPENY--HGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPGLVS 308
G +C CP Y D +C D C + L C S +C G C C PG+
Sbjct: 2273 --GSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMC-KNLIGTFMCICPPGMA- 2328
Query: 309 INSNASAGCF----AFCSPFSCDRSATCQVTADGKTSCVCRE--SEVGDGRACYGHLLHE 362
GC P C+ + G C C E G C +
Sbjct: 2329 -RRPDGEGCVDENECRTKPGICENGRCVNII--GSYRCECNEGFQSSSSGTECLDN---- 2381
Query: 363 VQKATQTGRVFLQLRVAVAMMDQGCREILT 392
+ G F ++ + M R ++T
Sbjct: 2382 -----RQGLCFAEVLQTICQMASSSRNLVT 2406
Score = 53.1 bits (126), Expect = 3e-06
Identities = 75/297 (25%), Positives = 100/297 (33%), Gaps = 57/297 (19%)
Query: 712 NQTIMEQGCCKGFFGPDCTQCPGGF-----SNPCYGKGNCS-DGIQGNGACLCFPDYKGI 765
N + E G C G +C GF S C CS I G C P
Sbjct: 1456 NINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNICVFGTCNNLPGMFHC 1515
Query: 766 ACHICSNPNKHG------EQCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESM 819
C ++ G ++C + CV+GLC N PG + C P F
Sbjct: 1516 ICDDGYELDRTGGNCTDIDECADPINCVNGLCVNTPGR----YECNCPPDF--------- 1562
Query: 820 GDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGDG-FSC--------TPSNPCSHPDR 870
PTG+ CV V C G GDG SC + S+ C +
Sbjct: 1563 -QLNPTGVG--------CVDNR-VGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGK 1612
Query: 871 GGCSENAECVPGSLGTHHCTCHKGWSGDG-------RVCVAIDECELDMRGGCHTDALCS 923
+ C P + ++ C G+G + IDEC+ ++ G C +
Sbjct: 1613 AWGNPCETCPPVNSTEYYTLCP---GGEGFRPNPITIILEDIDECQ-ELPGLCQGGNCIN 1668
Query: 924 YVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGF 980
G Q C + D C ID C A G C G TC G C CPP +
Sbjct: 1669 TFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVC-GPGTCYNTLGNY-TCICPPEY 1723
Score = 52.8 bits (125), Expect = 4e-06
Identities = 64/249 (25%), Positives = 85/249 (34%), Gaps = 66/249 (26%)
Query: 1957 PSCCPGHYGSECQACPGGPSSPCSD-------RGVCMDGM-SGSGQCLCRSGFAGTACEL 2008
P+ C + S C CPG + P + R C DG S C C SG + C
Sbjct: 86 PNVCGSRFHSYC--CPGWKTLPGGNQCIVPICRNSCGDGFCSRPNMCTCSSGQISSTC-- 141
Query: 2009 CAPGAFGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEA 2068
G+ + RC G C + C C +G+ G C QPVC C
Sbjct: 142 ---GSKSIQQCSVRCMNGGTCADD-----HCQCQKGYIGTYCG-----QPVCENGCQNGG 188
Query: 2069 VCRAGNSCECSLGYEGDGRVCTVADLCQDGH--GGCSEHAN---CSQVGTMVTCT---CL 2120
C N C C G+ G C+ + G C N C T + CT C
Sbjct: 189 RCIGPNRCACVYGFTG--------PQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCC 240
Query: 2121 PDYEGDGWS-----CRAR-NPCTDG-----HRGGCS------------EHANCLSTGLNT 2157
G W C A+ PC G G C + NC++T + +
Sbjct: 241 ATI-GRAWGHPCEMCPAQPQPCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINT-VGS 298
Query: 2158 RRCECHAGY 2166
C C AG+
Sbjct: 299 FECRCPAGH 307
Score = 50.8 bits (120), Expect = 2e-05
Identities = 79/313 (25%), Positives = 112/313 (35%), Gaps = 69/313 (22%)
Query: 709 SYCNQTIMEQGCCKG--FFGPDCTQCPGGFSNP-C---YGKGNCSDGIQGNGACLCFPDY 762
+YC Q + E GC G GP+ C GF+ P C Y G C + +C
Sbjct: 173 TYCGQPVCENGCQNGGRCIGPNRCACVYGFTGPQCERDYRTGPCFTQVNNQ---MCQGQL 229
Query: 763 KGIACHICSNPNKHGEQCQEDCGCVHG-LCDNRPGSGGVCQQGTCAPGFSGRFCNESMGD 821
GI C C G G C+ P C++G P C +
Sbjct: 230 TGIVC--------TKTLCCATIGRAWGHPCEMCPAQPQPCRRG-FIPNIRTGACQDVDEC 280
Query: 822 CGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGDGFS--CTPSNPCSHPDRGGCSENAEC 879
G+ Q C++ G CRC G + + C + CS G E EC
Sbjct: 281 QAIPGICQ----GGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIP--GICETGEC 334
Query: 880 VPGSLGTHHCTCHKGW--SGDGRVCVAIDECELDMRGGCHTDALCSYVGPGQSRCTCKLG 937
++G++ C C +G+ S DG C+ D R G +C + G RC +L
Sbjct: 335 -SNTVGSYFCVCPRGYVTSTDGSRCI-------DQRTG-----MC-FSGLVNGRCAQELP 380
Query: 938 FAGDGYQCSPIDPCRAGNGGCHGLAT----CRAVGGGQ--RVC--------------TCP 977
QC C G C G+ T C G + R+C + P
Sbjct: 381 GRMTKMQCC----CEPGR--CWGIGTIPEACPVRGSEEYRRLCMDGLPMGGIPGSAGSRP 434
Query: 978 PGFGGDGFSCYGD 990
G GG+GF+ G+
Sbjct: 435 GGTGGNGFAPSGN 447
Score = 50.8 bits (120), Expect = 2e-05
Identities = 75/321 (23%), Positives = 98/321 (30%), Gaps = 112/321 (34%)
Query: 55 CPSGWLRELPDQITQDCRYEVQLGGSMVSMSGCRRKCRKQVVQKACC---PGY-WGSRCH 110
CP G + ++ D G + C R V + CC P Y +G C
Sbjct: 684 CPPGLAVGMDGRVCVDTHMRSTCYGG-IKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQ 742
Query: 111 ECPGGAETPCNGHGTC-------LDGMD-----------RNGTCVCQENFRGSA---CQE 149
CP A+ HG C +DG D NG C EN RGS C
Sbjct: 743 PCP--AKNSAEFHGLCSSGVGITVDGRDINECALDPDICANGIC---ENLRGSYRCNCNS 797
Query: 150 CQDPNRFGPDCQSVCSCV-------HGVCNHGPRGDGSCLCFAGY---TGPHCDQELPVC 199
+P+ G +C + C+ +G+C + P G SC C GY T +++ C
Sbjct: 798 GYEPDASGRNCIDIDECLVNRLLCDNGLCRNTP-GSYSCTCPPGYVFRTETETCEDINEC 856
Query: 200 QELRCPQNTQCSAEAPS--CRCLPGY---------------------------------T 224
+ C N C S C C PG T
Sbjct: 857 ESNPCV-NGACRNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGAT 915
Query: 225 QQGSECRAPNPCWPSPCSL---------------------LAQCSVSP-----------K 252
+ C W SPC + +C V P K
Sbjct: 916 LKSECCATLGAAWGSPCERCELDTACPRGLARIKGVTCEDVNECEVFPGVCPNGRCVNSK 975
Query: 253 GQAQCHCPE--NYHGDGMVCL 271
G C CPE G G VCL
Sbjct: 976 GSFHCECPEGLTLDGTGRVCL 996
Score = 50.1 bits (118), Expect = 3e-05
Identities = 71/287 (24%), Positives = 102/287 (35%), Gaps = 65/287 (22%)
Query: 1946 CHRNCVTTTWKPSC-CPGHYG--------SECQACPGGPSSPCSDRGVCMDGMSGSGQCL 1996
C C+ T C CP Y + C G C RG+ + G+ C+
Sbjct: 2264 CAFRCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHD-CESRGMMCKNLIGTFMCI 2322
Query: 1997 CRSGFA----GTACELCAPGAFGPHCQACRCTVHGRCDEG----LGGSGSCFCDEGW--T 2046
C G A G C CR T G C+ G + GS C C+EG+ +
Sbjct: 2323 CPPGMARRPDGEGC---------VDENECR-TKPGICENGRCVNIIGSYRCECNEGFQSS 2372
Query: 2047 GPRCEVQLELQPVCTPPCAPEAVCRAGNSCECSLGYEGDGRVCTVADLCQDGHGGCSEHA 2106
E Q +C + +C+ +S + T ++ C DG G
Sbjct: 2373 SSGTECLDNRQGLCFAEVL-QTICQMASSSR---------NLVTKSECCCDGGRGWGHQC 2422
Query: 2107 N-CSQVGT---MVTCTCLPDYEGDGW---SCRAR-NPCTDGHRGGCSEHANCLSTGLNTR 2158
C GT C P Y DG C+ N CT+G C++T + +
Sbjct: 2423 ELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTNG---------QCINT-MGSF 2472
Query: 2159 RCECHAGYVGD--GLQCLEESEPPVDRCLGQPPPCHSDAMCTDLHFQ 2203
RC C GY D G C++ +D C P PC+ T+ +Q
Sbjct: 2473 RCFCKVGYTTDISGTSCID-----LDECSQSPKPCNYICKNTEGSYQ 2514
Score = 49.7 bits (117), Expect = 4e-05
Identities = 76/314 (24%), Positives = 99/314 (31%), Gaps = 70/314 (22%)
Query: 85 SGCRRKCRKQVVQKACCPGYWGSRCHE--CPGGAETPCNGH-------GTCLDGM-DRNG 134
S RR+ ++ V++ P GSR H CPG P +C DG R
Sbjct: 72 SRVRRRGQQDVLRG---PNVCGSRFHSYCCPGWKTLPGGNQCIVPICRNSCGDGFCSRPN 128
Query: 135 TCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQ 194
C C S C +S+ C N G D C C GY G +C Q
Sbjct: 129 MCTCSSGQISSTCGS-----------KSIQQCSVRCMNGGTCADDHCQCQKGYIGTYCGQ 177
Query: 195 ELPVCQE-----LRCPQNTQCSA----EAPSC----RCLPGYTQQGSE------------ 229
PVC+ RC +C+ P C R P +TQ ++
Sbjct: 178 --PVCENGCQNGGRCIGPNRCACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCT 235
Query: 230 ----CRAPNPCWPSPCSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPS 285
C W PC + C P+ + P G C D C G C
Sbjct: 236 KTLCCATIGRAWGHPCEM---CPAQPQPCRRGFIPNIRTG---ACQDVDECQAIPGICQG 289
Query: 286 NSTLCVYQKPGQAFCTCRPGLVSINSNASAGCFAFCS--PFSCDRSATCQVTADGKTSCV 343
+ + G C C G + CS P C+ + C T G CV
Sbjct: 290 GNCI---NTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICE-TGECSNTV-GSYFCV 344
Query: 344 CRESEV--GDGRAC 355
C V DG C
Sbjct: 345 CPRGYVTSTDGSRC 358
Score = 49.3 bits (116), Expect = 5e-05
Identities = 75/291 (25%), Positives = 103/291 (35%), Gaps = 72/291 (24%)
Query: 1949 NCVTTTWKPSCCPGHYGSECQACPGGPSSP----------CSDRGV-CMDGM----SGSG 1993
+CV T PG Y +C A G +P C GV C +G GS
Sbjct: 548 DCVNT-------PGSYYCKCHA--GFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSF 598
Query: 1994 QCLCRSGFAGTACELCAPGAFGPHC-QACRCTVHGRCDEGL----GGSGSCFCDEGWT-G 2047
QC+C +GF T G +C CT C G+ GS C C G+
Sbjct: 599 QCICNAGFELT--------TDGKNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLA 650
Query: 2048 PRCEVQLELQPVCTPPCAPEAVC---RAGNSCEC--SLGYEGDGRVCTVADLCQDGHGGC 2102
P ++ TP C C+C L DGRVC + +GG
Sbjct: 651 PNGRYCTDVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGI 710
Query: 2103 SEHANCSQVGTMVT----CTCLPDYEGDGWSCR---ARNP------CTDG--------HR 2141
+ VT C PDY G G C+ A+N C+ G
Sbjct: 711 KKGVCVRPFPGAVTKSECCCANPDY-GFGEPCQPCPAKNSAEFHGLCSSGVGITVDGRDI 769
Query: 2142 GGCSEHANCLSTGL-----NTRRCECHAGYVGD--GLQCLEESEPPVDRCL 2185
C+ + + G+ + RC C++GY D G C++ E V+R L
Sbjct: 770 NECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLL 820
Score = 46.6 bits (109), Expect = 3e-04
Identities = 81/339 (23%), Positives = 112/339 (33%), Gaps = 79/339 (23%)
Query: 712 NQTIMEQGCCKGFFGPDCTQCPGGF----------------SNPCYGKGNCSDGIQGNGA 755
N+ + + G C+ G CP G+ SNPC G C + + G+
Sbjct: 817 NRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNPCVN-GACRNNL-GSFN 874
Query: 756 CLCFPDYK----GIAC-----HIC--------SNPNKHGEQCQEDCGCVHGLCDNRPGSG 798
C C P K G+ C C N +G + +C G P
Sbjct: 875 CECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCER 934
Query: 799 GVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDG--FEGDG 856
C+ T P R + D + + RCV+ +G C C +G +G G
Sbjct: 935 --CELDTACPRGLARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTG 992
Query: 857 FSCT-----------PSNPCSHPDRGGCSENAEC--VPGSLGTHHCTCHK---------- 893
C + C HP G +A C V + GT C K
Sbjct: 993 RVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLC 1052
Query: 894 ----GWSGDGRVCVA------IDECELDMRGGCHTDALCSYVGPGQSRCTCKLGFAGDGY 943
G++ G V I+EC+ G C T C G +C C GFA D
Sbjct: 1053 PRGAGFANRGDVLTGRPFYKDINECKA-FPGMC-TYGKCRNT-IGSFKCRCNSGFALDME 1109
Query: 944 Q--CSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGF 980
+ C+ ID CR C G C G C C G+
Sbjct: 1110 ERNCTDIDECRISPDLC-GSGICVNTPGSFE-CECFEGY 1146
Score = 46.2 bits (108), Expect = 4e-04
Identities = 66/274 (24%), Positives = 92/274 (33%), Gaps = 66/274 (24%)
Query: 120 CNGHGTCLDGM----DRNGTCVCQENF----RGSACQECQDPNRFGPDCQSVCSCVHGVC 171
C CL+GM D + C+C+ F G C + + CQ+ C++G C
Sbjct: 621 CTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDE-------CQTPGICMNGHC 673
Query: 172 NHGPRGDGSCLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAPSC-RCLPGYTQQGSEC 230
+ G C C G + VC + + C R PG + SEC
Sbjct: 674 INS-EGSFRCDCPPGLA---VGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTK-SEC 728
Query: 231 RAPNP-------CWPSP----------CSL----------LAQCSVSP-----------K 252
NP C P P CS + +C++ P +
Sbjct: 729 CCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGRDINECALDPDICANGICENLR 788
Query: 253 GQAQCHCPENYHGD--GMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPGLVSIN 310
G +C+C Y D G C+ D C N C + LC PG CTC PG V
Sbjct: 789 GSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNG--LC-RNTPGSYSCTCPPGYVFRT 845
Query: 311 SNASAGCFAFCSPFSCDRSATCQVTADGKTSCVC 344
+ C C A C+ G +C C
Sbjct: 846 ETETCEDINECESNPCVNGA-CRNNL-GSFNCEC 877
Score = 46.2 bits (108), Expect = 4e-04
Identities = 75/295 (25%), Positives = 107/295 (36%), Gaps = 72/295 (24%)
Query: 1949 NCVTTTWKPSC-CP-GHYGSE----------CQACPG--GPSSPCSDRG----VCMDG-- 1988
NC+ T C CP G+Y SE C A PG GP + + G +C
Sbjct: 1665 NCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYM 1724
Query: 1989 -MSGSGQCL------CRSGFAGTACELCAPGAFGPHCQACRCTVH--------------- 2026
++G C+ C + GT CE P F + C CT +
Sbjct: 1725 QVNGGHNCMDMRKSFCYRSYNGTTCENELP--FNVTKRMCCCTYNVGKAWNKPCEPCPTP 1782
Query: 2027 GRCD-EGLGGSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEAVC--RAGN-SCECSLGY 2082
G D + + G+ F + TG ++ E + + P VC + G+ CEC G+
Sbjct: 1783 GTADFKTICGNIPGFTFDIHTGKAVDID-ECKEI--PGICANGVCINQIGSFRCECPTGF 1839
Query: 2083 EGDGR--VCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWSCRARNPCTDGH 2140
+ VC D C +G C +A+C C C G+ C D
Sbjct: 1840 SYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCEC-----AAGFKLSPNGACVD-- 1892
Query: 2141 RGGCSEHANCLSTGL-----NTRRCECHAGYVG--DGLQCLEESEPPVDRCLGQP 2188
R C E N S GL + +C CH G+ D C++ VD C P
Sbjct: 1893 RNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMD-----VDECERHP 1942
Score = 45.8 bits (107), Expect = 5e-04
Identities = 72/273 (26%), Positives = 101/273 (36%), Gaps = 40/273 (14%)
Query: 1338 GVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCTGVC--DCAHGLCQEGLQ 1395
G+C G+C + +GS C C G+ + + R TG+C +G C + L
Sbjct: 327 GICET-GECSNT-VGSYFCVCPRGYVTST----DGSRCIDQRTGMCFSGLVNGRCAQELP 380
Query: 1396 GDGS---CVCNVGWQGLRCDQKITSPQ-CP-RKCDPNANCVQDSAGASTCACAAGYSGNG 1450
G + C C G RC T P+ CP R + D +AG G
Sbjct: 381 GRMTKMQCCCEPG----RCWGIGTIPEACPVRGSEEYRRLCMDGLPMGGIPGSAGSRPGG 436
Query: 1451 IFCSEVDPCAHGHG------GCSPHANCTKVAPGQRTCTCQDGYMGD-----GELCQEIN 1499
+ P +G+G G P +PG G G L Q I+
Sbjct: 437 TGGNGFAPSGNGNGYGPGGTGFIPIPGGNGFSPGVGGAGVGAGGQGPIITGLTILNQTID 496
Query: 1500 SCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLDPCSKN---NGGC--SPY 1554
C HH ++ CIPT C C GY D C +D C+ N NG C +P
Sbjct: 497 ICK-HHANLCLNGRCIPT-VSSYRCECNMGYKQDANGDCIDVDECTSNPCTNGDCVNTPG 554
Query: 1555 A-TCKSTGDGQRTCT----CDTAHTVGDGLTCR 1582
+ CK QRT T D + +G+ C+
Sbjct: 555 SYYCKCHAGFQRTPTKQACIDIDECIQNGVLCK 587
Score = 45.4 bits (106), Expect = 7e-04
Identities = 91/418 (21%), Positives = 122/418 (29%), Gaps = 113/418 (27%)
Query: 664 GSCVDCQALNTSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKGCASYCNQTIMEQGCCKG 723
G CV+ C +L K CV + T N+ G I E G K
Sbjct: 589 GRCVNTDGSFQCICNAG-FELTTDGKNCVDHDECTTTNMCLNGMC------INEDGSFKC 641
Query: 724 FFGPDCTQCPGGFS----NPCYGKGNCSDG----IQGNGACLCFPD-------------- 761
P P G + C G C +G +G+ C C P
Sbjct: 642 ICKPGFVLAPNGRYCTDVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTH 701
Query: 762 -----YKGIACHICSNPNKHGEQCQEDCGCV---HGL---CDNRPGSGGVCQQGTCAPGF 810
Y GI +C P G + +C C +G C P G C+ G
Sbjct: 702 MRSTCYGGIKKGVCVRPFP-GAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGV 760
Query: 811 SGRFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGD--------------- 855
+ +C L + C + G RC C G+E D
Sbjct: 761 GITVDGRDINECA---LDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVN 817
Query: 856 --------------GFSCT--------------------PSNPCSHPDRGGC-----SEN 876
+SCT SNPC + G C S N
Sbjct: 818 RLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNPCVN---GACRNNLGSFN 874
Query: 877 AECVPGS-LGTHHCTCHKGWSGDGRVCVAIDECELDMRGGCHTDALCSYVGPGQ----SR 931
EC PGS L + C G + + CE+++ G C+ +G R
Sbjct: 875 CECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCER 934
Query: 932 C----TCKLGFAG-DGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGFGGDG 984
C C G A G C ++ C G C + G C CP G DG
Sbjct: 935 CELDTACPRGLARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFH--CECPEGLTLDG 990
Score = 44.3 bits (103), Expect = 0.002
Identities = 66/254 (25%), Positives = 84/254 (33%), Gaps = 48/254 (18%)
Query: 120 CNGHGTCLDGMDR-NGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVH---GVC--NH 173
C C D ++ NG CV N G EC P F + V CV G C
Sbjct: 1530 CTDIDECADPINCVNGLCV---NTPGR--YECNCPPDFQLNPTGV-GCVDNRVGNCYLKF 1583
Query: 174 GPRGDGSCLC----FAGYTGPHCDQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQ-QGS 228
GPRGDGS C G + C C L C P YT G
Sbjct: 1584 GPRGDGSLSCNTEIGVGVSRSSC------CCSLGKAWGNPCET-CPPVNSTEYYTLCPGG 1636
Query: 229 ECRAPNP----------CWPSPCSLLAQCSVSPKGQAQCHCPENYH--GDGMVCLPKDPC 276
E PNP C P ++ G QC CP+ Y+ D +C D C
Sbjct: 1637 EGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDEC 1696
Query: 277 TDNLGGCPSNSTLCVYQKPGQAFCTCRPGLVSINSN------ASAGCFAFCSPFSCDRSA 330
+ G C + Y G C C P + +N + C+ + +C+
Sbjct: 1697 FAHPGVCGPGT---CYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENEL 1753
Query: 331 TCQVTADGKTSCVC 344
VT K C C
Sbjct: 1754 PFNVT---KRMCCC 1764
Score = 43.1 bits (100), Expect = 0.004
Identities = 74/333 (22%), Positives = 110/333 (33%), Gaps = 81/333 (24%)
Query: 87 CRRKCRKQVVQKACCPGY---WGSRCHECPGGAETPC-----NGHG-------------- 124
C + V + +CC WG+ C CP T G G
Sbjct: 1593 CNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDID 1652
Query: 125 TC--LDGMDRNGTCVCQENFRGSACQECQDPNRFGPD---CQSVCSCVH--GVCNHGP-- 175
C L G+ + G C+ N GS EC D C+ + C GVC G
Sbjct: 1653 ECQELPGLCQGGNCI---NTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCY 1709
Query: 176 -----------------RGDGSCL------CFAGYTGPHCDQELP--VCQELRC------ 204
G +C+ C+ Y G C+ ELP V + + C
Sbjct: 1710 NTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVG 1769
Query: 205 --------PQNTQCSAEAPS-CRCLPGYTQQGSECRAP--NPCWPSPCSLLAQCSVSPKG 253
P T +A+ + C +PG+T +A + C P ++ G
Sbjct: 1770 KAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGICANGVCINQIG 1829
Query: 254 QAQCHCPE--NYHGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPGLVSINS 311
+C CP +Y+ +VC D C++ C N+ C+ PG C C G ++
Sbjct: 1830 SFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNAD-CI-NSPGSYRCECAAGF-KLSP 1886
Query: 312 NASAGCFAFCSPFSCDRSATCQVTADGKTSCVC 344
N + C S V G C+C
Sbjct: 1887 NGACVDRNECLEIPNVCSHGLCVDLQGSYQCIC 1919
Score = 41.6 bits (96), Expect = 0.010
Identities = 76/340 (22%), Positives = 107/340 (31%), Gaps = 112/340 (32%)
Query: 1319 DCCPGFFGTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPN 1378
D C FFG +C +G+C + +GS +C C+EG+ EL G N
Sbjct: 1975 DECSSFFGQVCR------------NGRCFNE-IGSFKCLCNEGY--------ELTPDGKN 2013
Query: 1379 C--TGVC-----DCAHGLCQEGLQGD-------------------------------GSC 1400
C T C C+ G CQ L+G GSC
Sbjct: 2014 CIDTNECVALPGSCSPGTCQN-LEGSFRCICPPGYEVKSENCIDINECDEDPNICLFGSC 2072
Query: 1401 VCNVGWQGLRCDQKITSPQCPRKCDP-----------NANCVQDSAGAST---CACAA-- 1444
G C R+C N C A +T C C+
Sbjct: 2073 TNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMP 2132
Query: 1445 --GYSGNGIFCSEVDP------CAHGHG-------------------GCSPHANCTKVAP 1477
G+ C + D C +GHG G + C
Sbjct: 2133 GEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNGQCINT-D 2191
Query: 1478 GQRTCTCQDGYMGD--GELCQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGI 1535
G C C GY D G C + + C I G + C C+C EG+ +
Sbjct: 2192 GSFRCECPMGYNLDYTGVRCVDTDECSI--GNPCGNGTCTNV-IGSFECNCNEGFEPGPM 2248
Query: 1536 RTCELLDPCSKNNGGCSPYATCKSTGDGQRTCTCDTAHTV 1575
CE ++ C++N C+ C +T G CTC + +
Sbjct: 2249 MNCEDINECAQNPLLCA--FRCMNT-FGSYECTCPIGYAL 2285
Score = 39.7 bits (91), Expect = 0.039
Identities = 74/332 (22%), Positives = 101/332 (30%), Gaps = 98/332 (29%)
Query: 101 CPGYWGSRCHECPGGAETPCNGHGTCLD--------------------GMDRNGTCVCQE 140
C GS ECP G G CLD G R C C
Sbjct: 971 CVNSKGSFHCECPEGLTLDGTGR-VCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAV 1029
Query: 141 NFR-GSACQECQDPNRFGPDCQSVCSCVHGVCNHGPRGDG--------SCLCFAGYTGPH 191
G+ C+EC P + +++C G N G G C F G
Sbjct: 1030 GAAWGTECEECPKPGT--KEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPG----- 1082
Query: 192 CDQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQGSE--CRAPNPCWPSPCSLLAQCSV 249
+C +C +NT S + CRC G+ E C + C SP + V
Sbjct: 1083 ------MCTYGKC-RNTIGSFK---CRCNSGFALDMEERNCTDIDECRISPDLCGSGICV 1132
Query: 250 SPKGQAQCHCPENYHGDGMV---CLPKDPCTDN--------------------------- 279
+ G +C C E Y M+ C+ D C N
Sbjct: 1133 NTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELS 1192
Query: 280 --------LGGCPSNSTLCVYQK----PGQAFCTCRPGLVSINSNASAGCFAFCSPFS-- 325
+ C + LC K G C+C PG + C +
Sbjct: 1193 PSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGG 1252
Query: 326 CDRSATCQVTADGKTSCVCRE--SEVGDGRAC 355
CD T ++G C C E + + DGR+C
Sbjct: 1253 CDTQCT---NSEGSYECSCSEGYALMPDGRSC 1281
Score = 39.7 bits (91), Expect = 0.039
Identities = 77/319 (24%), Positives = 106/319 (33%), Gaps = 81/319 (25%)
Query: 1948 RNCVTT--------TWKPSCCPGHYGSECQACPGG---PSSPC-------SDRGVCMDGM 1989
+NC+ T + P C GS CP G S C D +C+ G
Sbjct: 2012 KNCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSENCIDINECDEDPNICLFGS 2071
Query: 1990 S----GSGQCLCRSGFA----GTACELCAPGAFGPHCQACRCTVHGRCDEGLGGSGSCFC 2041
G QCLC GF G C + + +C+V + C C
Sbjct: 2072 CTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTT---KAKCCC 2128
Query: 2042 D----EGWTGPRCEV-----QLELQPVC-----TPPCAPEA------------VCRAGNS 2075
EGW P CE+ ++ Q +C T P + +C G
Sbjct: 2129 SKMPGEGWGDP-CELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNGQC 2187
Query: 2076 --------CECSLGYEGD--GRVCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPDYE- 2124
CEC +GY D G C D C G+ C + C+ V C C +E
Sbjct: 2188 INTDGSFRCECPMGYNLDYTGVRCVDTDECSIGN-PCG-NGTCTNVIGSFECNCNEGFEP 2245
Query: 2125 GDGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYV--GDGLQCLEESEPPVD 2182
G +C N C C+ C++T + C C GY D C + +D
Sbjct: 2246 GPMMNCEDINECAQNPL-LCA--FRCMNT-FGSYECTCPIGYALREDQKMCKD-----LD 2296
Query: 2183 RCLGQPPPCHS-DAMCTDL 2200
C C S MC +L
Sbjct: 2297 ECAEGLHDCESRGMMCKNL 2315
Score = 36.2 bits (82), Expect = 0.43
Identities = 35/135 (25%), Positives = 46/135 (34%), Gaps = 43/135 (31%)
Query: 105 WGSRCHECPGGAETPCNGH-------GTCLD--------GMDRNGTCVCQENFRGSACQE 149
WG C CP + PC G C D G+ + G C+ C
Sbjct: 247 WGHPCEMCPAQPQ-PCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRCPA 305
Query: 150 CQDPNRFGPDCQSV--CSCVHGVCNHG-------------PRG-----DGS-CL------ 182
+ C+ + CS + G+C G PRG DGS C+
Sbjct: 306 GHKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGM 365
Query: 183 CFAGYTGPHCDQELP 197
CF+G C QELP
Sbjct: 366 CFSGLVNGRCAQELP 380
>gi|110735443 delta-like 1 [Homo sapiens]
Length = 723
Score = 105 bits (263), Expect = 4e-22
Identities = 85/266 (31%), Positives = 112/266 (42%), Gaps = 41/266 (15%)
Query: 1309 YTCAKKIQVPDCCPGFFGTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACE 1368
+TC ++ + C PG+ G C P L G HG C GEC C G+ G C+
Sbjct: 202 FTCGERGEKV-CNPGWKGPYCTE-PICLPGCDEQHGFCDK----PGECKCRVGWQGRYCD 255
Query: 1369 VCELGRYGPNCTGVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNA 1428
C RY C HG CQ+ Q C C GW GL C+Q + + C A
Sbjct: 256 ECI--RYP-------GCLHGTCQQPWQ----CNCQEGWGGLFCNQDLNYCTHHKPCKNGA 302
Query: 1429 NCVQDSAGASTCACAAGYSGN----GIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTC 1484
C G+ TC+C GY+G GI + PC +G G C+ N +CTC
Sbjct: 303 TCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKNG-GSCTDLEN-------SYSCTC 354
Query: 1485 QDGYMGDGELCQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCE-LLDP 1543
G+ G++C E+++ G C C + SC C GYSG CE +D
Sbjct: 355 PPGFY--GKIC-ELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSG---FNCEKKIDY 408
Query: 1544 CSKNNGGCSPYATCKSTGDGQRTCTC 1569
CS + CS A C GD C C
Sbjct: 409 CS--SSPCSNGAKCVDLGDAY-LCRC 431
Score = 95.9 bits (237), Expect = 5e-19
Identities = 74/246 (30%), Positives = 101/246 (41%), Gaps = 41/246 (16%)
Query: 1342 GHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCTGVCDCAHGLCQEGLQGDGSCV 1401
GH C +R GE C+ G+ G C P C CD HG C + G C
Sbjct: 200 GHFTCGER----GEKVCNPGWKGPYCTE-------PICLPGCDEQHGFCDK----PGECK 244
Query: 1402 CNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTCACAAGYSGNGIFCSE-VDPCA 1460
C VGWQG CD+ I P C + C Q C C G+ G +FC++ ++ C
Sbjct: 245 CRVGWQGRYCDECIRYPGCL-----HGTCQQPWQ----CNCQEGWGG--LFCNQDLNYCT 293
Query: 1461 HGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQ-EINSCLIHHGGCHIHAECIPTGP 1519
H H C A CT G TC+C+ GY G C+ I+ C C C
Sbjct: 294 H-HKPCKNGATCTNTGQGSYTCSCRPGYT--GATCELGIDEC--DPSPCKNGGSCTDL-E 347
Query: 1520 QQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKSTGDGQRTCTCDTAHTVGDGL 1579
SC+C G+ G + CEL + +G C C + DG +C C ++ G
Sbjct: 348 NSYSCTCPPGFYG---KICEL-SAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYS---GF 400
Query: 1580 TCRARV 1585
C ++
Sbjct: 401 NCEKKI 406
Score = 95.1 bits (235), Expect = 8e-19
Identities = 78/265 (29%), Positives = 95/265 (35%), Gaps = 42/265 (15%)
Query: 1945 GCHRNCVTTTWKPSCCPGHYGSECQA----CPGGPSSPCSDRGVCMDGMSGSGQCLCRSG 2000
GC W+ +C G G C C PC + C + GS C CR G
Sbjct: 262 GCLHGTCQQPWQCNCQEGWGGLFCNQDLNYCTH--HKPCKNGATCTNTGQGSYTCSCRPG 319
Query: 2001 FAGTACELCAPGAFGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPVC 2060
+ G CEL C C G C + L S SC C G+ G CE L
Sbjct: 320 YTGATCELGI-----DECDPSPCKNGGSCTD-LENSYSCTCPPGFYGKICE--LSAMTCA 371
Query: 2061 TPPCAPEAVCR----AGNSCECSLGYEGDGRVCTVADLCQDGHGGCSEHANCSQVGTMVT 2116
PC C G SC C +GY G + D C CS A C +G
Sbjct: 372 DGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKI-DYCSS--SPCSNGAKCVDLGDAYL 428
Query: 2117 CTCLPDYEG----DGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGDGLQ 2172
C C + G D A +PC +G G C + G+N C C GY G
Sbjct: 429 CRCQAGFSGRHCDDNVDDCASSPCANG--GTCRD-------GVNDFSCTCPPGYTG---- 475
Query: 2173 CLEESEPPVDRCLGQPPPCHSDAMC 2197
PV RC + PCH+ A C
Sbjct: 476 --RNCSAPVSRC--EHAPCHNGATC 496
Score = 90.9 bits (224), Expect = 1e-17
Identities = 70/227 (30%), Positives = 90/227 (39%), Gaps = 20/227 (8%)
Query: 1958 SCCPGHYGSECQ-ACPGGPSSPCSDRGVCMDGMSGSGQCLCRSGFAGTACELCAPGAFGP 2016
SC PG+ G+ C+ SPC + G C D + S C C GF G CEL A
Sbjct: 315 SCRPGYTGATCELGIDECDPSPCKNGGSCTD-LENSYSCTCPPGFYGKICELSAMT---- 369
Query: 2017 HCQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEAVC-RAGNS 2075
C C GRC + G SC C G++G CE +++ + PC+ A C G++
Sbjct: 370 -CADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDY--CSSSPCSNGAKCVDLGDA 426
Query: 2076 --CECSLGYEGDGRVCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWSCRAR 2133
C C G+ G V D C+ C +CTC P Y G S
Sbjct: 427 YLCRCQAGFSGRHCDDNVDDCASSP---CANGGTCRDGVNDFSCTCPPGYTGRNCSA--- 480
Query: 2134 NPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGDGLQCLEESEPP 2180
P + C A C G + CEC GY G Q L PP
Sbjct: 481 -PVSRCEHAPCHNGATCHERG-HRYVCECARGYGGPNCQFLLPELPP 525
Score = 89.7 bits (221), Expect = 3e-17
Identities = 91/299 (30%), Positives = 120/299 (40%), Gaps = 64/299 (21%)
Query: 710 YCNQTIMEQGC----CKGFFGPDCTQCPGG-FSN----------PCYGKGNCSDGIQGNG 754
YC++ I GC C+ + +C + GG F N PC C++ QG+
Sbjct: 253 YCDECIRYPGCLHGTCQQPWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSY 312
Query: 755 ACLCFPDYKGIACHI----CS-NPNKHGEQCQEDCGCVHGLCDNRPGSGGVCQQGTCAPG 809
C C P Y G C + C +P K+G C + +N TC PG
Sbjct: 313 TCSCRPGYTGATCELGIDECDPSPCKNGGSCTD--------LEN-------SYSCTCPPG 357
Query: 810 FSGRFCNESMGDC--GPTGLAQHCHLHARCV-SQEGVARCRCLDGFEGDGFSCTPSNPCS 866
F G+ C S C GP C RC S +G CRC G+ GF+C
Sbjct: 358 FYGKICELSAMTCADGP------CFNGGRCSDSPDGGYSCRCPVGY--SGFNC--EKKID 407
Query: 867 HPDRGGCSENAECVPGSLG-THHCTCHKGWSGDGRVC-VAIDECELDMRGGCHTDALCSY 924
+ CS A+CV LG + C C G+S GR C +D+C C C
Sbjct: 408 YCSSSPCSNGAKCV--DLGDAYLCRCQAGFS--GRHCDDNVDDC---ASSPCANGGTCR- 459
Query: 925 VGPGQSRCTCKLGFAGDGYQCS-PIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGFGG 982
G CTC G+ G CS P+ C + CH ATC G + VC C G+GG
Sbjct: 460 DGVNDFSCTCPPGYT--GRNCSAPVSRCE--HAPCHNGATCHE-RGHRYVCECARGYGG 513
Score = 88.2 bits (217), Expect = 9e-17
Identities = 82/288 (28%), Positives = 110/288 (38%), Gaps = 55/288 (19%)
Query: 97 QKACCPGYWGSRCHE--CPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQEC-QDP 153
+K C PG+ G C E C G + HG C D+ G C C+ ++G C EC + P
Sbjct: 209 EKVCNPGWKGPYCTEPICLPGCDEQ---HGFC----DKPGECKCRVGWQGRYCDECIRYP 261
Query: 154 NRFGPDCQSV--CSCVHG-----------------------VCNHGPRGDGSCLCFAGYT 188
CQ C+C G C + +G +C C GYT
Sbjct: 262 GCLHGTCQQPWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYT 321
Query: 189 GPHCDQELPVCQELRCPQNTQCS--AEAPSCRCLPGYTQQGSECRAPNPCWPSPCSLLAQ 246
G C+ + C C C+ + SC C PG+ + E A C PC +
Sbjct: 322 GATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMT-CADGPCFNGGR 380
Query: 247 CSVSPKGQAQCHCPENYHGDGMVCLPK-DPCTDNLGGCPSNSTLCVYQKPGQAF-CTCRP 304
CS SP G C CP Y G C K D C+ + C SN CV G A+ C C+
Sbjct: 381 CSDSPDGGYSCRCPVGY--SGFNCEKKIDYCSSS--PC-SNGAKCV--DLGDAYLCRCQA 433
Query: 305 GLVSINSNASAGCFAFCSPFSCDRSATCQVTADGKT--SCVCRESEVG 350
G + + + C+ C TC+ DG SC C G
Sbjct: 434 GFSGRHCDDNVD---DCASSPCANGGTCR---DGVNDFSCTCPPGYTG 475
Score = 79.3 bits (194), Expect = 4e-14
Identities = 78/274 (28%), Positives = 110/274 (40%), Gaps = 56/274 (20%)
Query: 720 CCKGFFGPDCTQCPGGFSNP---CYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKH 776
C + ++G C+ F P +G C + G +C P +KG C+ P
Sbjct: 179 CDEHYYGEGCSV----FCRPRDDAFGHFTCGE----RGEKVCNPGWKG---PYCTEPI-- 225
Query: 777 GEQCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHAR 836
C C HG CD +PG C+ C G+ GR+C+E + G C LH
Sbjct: 226 ---CLPGCDEQHGFCD-KPGE---CK---CRVGWQGRYCDECIRYPG-------C-LHGT 267
Query: 837 CVSQEGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWS 896
C + +C C +G+ G F N C+H C A C G++ C+C G++
Sbjct: 268 C---QQPWQCNCQEGW-GGLFCNQDLNYCTH--HKPCKNGATCTNTGQGSYTCSCRPGYT 321
Query: 897 GDGRVC-VAIDECELD--MRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRA 953
G C + IDEC+ GG TD SY CTC GF G + +
Sbjct: 322 --GATCELGIDECDPSPCKNGGSCTDLENSY------SCTCPPGFYG---KICELSAMTC 370
Query: 954 GNGGCHGLATCRAVGGGQRVCTCPPGFGGDGFSC 987
+G C C G C CP G+ GF+C
Sbjct: 371 ADGPCFNGGRCSDSPDGGYSCRCPVGY--SGFNC 402
Score = 78.6 bits (192), Expect = 8e-14
Identities = 58/218 (26%), Positives = 89/218 (40%), Gaps = 33/218 (15%)
Query: 99 ACCPGYWGSRCH----ECPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPN 154
+C PGY G+ C EC +PC G+C D ++ + +C C F G C+
Sbjct: 315 SCRPGYTGATCELGIDECD---PSPCKNGGSCTD-LENSYSCTCPPGFYGKICELSAMTC 370
Query: 155 RFGPDCQSVCSCVHGV-CNHGPRGDGSCLCFAGYTGPHCDQELPVCQELRCPQNTQC--S 211
GP C +G C+ P G SC C GY+G +C++++ C C +C
Sbjct: 371 ADGP-------CFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDL 423
Query: 212 AEAPSCRCLPGYTQQGSEC-RAPNPCWPSPCSLLAQCSVSPKGQAQCHCPENYHGDGMVC 270
+A CRC G++ G C + C SPC+ C C CP Y G
Sbjct: 424 GDAYLCRCQAGFS--GRHCDDNVDDCASSPCANGGTCR-DGVNDFSCTCPPGYTGRN--- 477
Query: 271 LPKDPCTDNLGGC---PSNSTLCVYQKPGQAFCTCRPG 305
C+ + C P ++ +++ + C C G
Sbjct: 478 -----CSAPVSRCEHAPCHNGATCHERGHRYVCECARG 510
Score = 77.8 bits (190), Expect = 1e-13
Identities = 68/248 (27%), Positives = 87/248 (35%), Gaps = 50/248 (20%)
Query: 1969 QACPGGPSSPCSDRGVCMDGMSGS-------GQCLCRSGFAGTACELCA--PGAFGPHCQ 2019
+ C G P +C+ G G+C CR G+ G C+ C PG
Sbjct: 210 KVCNPGWKGPYCTEPICLPGCDEQHGFCDKPGECKCRVGWQGRYCDECIRYPGC------ 263
Query: 2020 ACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPVCT--PPCAPEAVC----RAG 2073
+HG C + C C EGW G C L CT PC A C +
Sbjct: 264 -----LHGTCQQ----PWQCNCQEGWGGLFCNQDLN---YCTHHKPCKNGATCTNTGQGS 311
Query: 2074 NSCECSLGYEGDGRVCTVA-DLCQDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWSCRA 2132
+C C GY G C + D C C +C+ + +CTC P + G A
Sbjct: 312 YTCSCRPGY--TGATCELGIDECDP--SPCKNGGSCTDLENSYSCTCPPGFYGKICELSA 367
Query: 2133 RNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGDGLQCLEESEPPVDRCLGQPPPCH 2192
C D G C C + C C GY G C E +D C PC
Sbjct: 368 MT-CAD---GPCFNGGRCSDSPDGGYSCRCPVGY--SGFNC----EKKIDYC--SSSPCS 415
Query: 2193 SDAMCTDL 2200
+ A C DL
Sbjct: 416 NGAKCVDL 423
Score = 74.7 bits (182), Expect = 1e-12
Identities = 91/340 (26%), Positives = 119/340 (35%), Gaps = 84/340 (24%)
Query: 1996 LCRSGFAGTACEL-CAP--GAFGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEV 2052
+C + G C + C P AFG H C E G C+ GW GP C
Sbjct: 178 VCDEHYYGEGCSVFCRPRDDAFG----------HFTCGE----RGEKVCNPGWKGPYC-- 221
Query: 2053 QLELQPVCTPPCAPE-AVCRAGNSCECSLGYEGDGRVCTVADLCQDGHGGCSEHANCSQV 2111
+P+C P C + C C+C +G++ GR C D C + GC H C Q
Sbjct: 222 ---TEPICLPGCDEQHGFCDKPGECKCRVGWQ--GRYC---DEC-IRYPGCL-HGTCQQP 271
Query: 2112 GTMVTCTCLPDYEGDGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGDGL 2171
C C + G + + N CT H C A C +TG + C C GY G
Sbjct: 272 W---QCNCQEGW-GGLFCNQDLNYCT--HHKPCKNGATCTNTGQGSYTCSCRPGYTG--- 322
Query: 2172 QCLEESEPPVDRCLGQPPPCHSDAMCTDLHFQEKRAGVFHLQATSGPYGLNFSEAEAACE 2231
E +D C P PC + CTDL + G YG CE
Sbjct: 323 ---ATCELGIDEC--DPSPCKNGGSCTDLE------NSYSCTCPPGFYG-------KICE 364
Query: 2232 AQGAVLASFP-----QLSAAQQLGFHL-CLMGWLANGSTAHPVVFPVADCGNGRVGIVSL 2285
A P + S + G+ C +G+ + C NG V L
Sbjct: 365 LSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNG-AKCVDL 423
Query: 2286 GARKNLSERWDAYCFRVQDVACRCRNGFVG----DGISTC 2321
G DAY CRC+ GF G D + C
Sbjct: 424 G---------DAY-------LCRCQAGFSGRHCDDNVDDC 447
Score = 61.6 bits (148), Expect = 1e-08
Identities = 58/243 (23%), Positives = 80/243 (32%), Gaps = 79/243 (32%)
Query: 664 GSCVDCQALNTSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKGCASYCNQTIMEQGCCKG 723
GSC D + + TCPP G
Sbjct: 341 GSCTDLENSYSCTCPP-------------------------------------------G 357
Query: 724 FFGPDC----TQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIAC-----HICSNPN 774
F+G C C G PC+ G CSD G +C C Y G C + S+P
Sbjct: 358 FYGKICELSAMTCADG---PCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPC 414
Query: 775 KHGEQCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLH 834
+G +C + G +C+ C GFSGR C++++ DC + C
Sbjct: 415 SNGAKCVD------------LGDAYLCR---CQAGFSGRHCDDNVDDCA----SSPCANG 455
Query: 835 ARCVSQEGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKG 894
C C C G+ G S P + C H C A C + C C +G
Sbjct: 456 GTCRDGVNDFSCTCPPGYTGRNCS-APVSRCEH---APCHNGATCHERG-HRYVCECARG 510
Query: 895 WSG 897
+ G
Sbjct: 511 YGG 513
Score = 61.6 bits (148), Expect = 1e-08
Identities = 50/176 (28%), Positives = 65/176 (36%), Gaps = 46/176 (26%)
Query: 1308 SYTCAKKIQVPDCCPGFFGTLCE-PCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTA 1366
SY+C C PGF+G +CE G C G+C D G C C G+ G
Sbjct: 349 SYSCT-------CPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFN 401
Query: 1367 CEV--------------------------CELGRYGPNCT-GVCDCAH------GLCQEG 1393
CE C+ G G +C V DCA G C++G
Sbjct: 402 CEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDG 461
Query: 1394 LQGDGSCVCNVGWQGLRCDQKITSPQCPR-KCDPNANCVQDSAGASTCACAAGYSG 1448
+ D SC C G+ G C ++ +C C A C + C CA GY G
Sbjct: 462 VN-DFSCTCPPGYTGRNCSAPVS--RCEHAPCHNGATC-HERGHRYVCECARGYGG 513
Score = 60.1 bits (144), Expect = 3e-08
Identities = 52/191 (27%), Positives = 65/191 (34%), Gaps = 33/191 (17%)
Query: 44 CTSCAAIKKQTCPSGWLRELPDQITQDCRYEVQLGGSMVSMS-----GCRRKCRKQVVQK 98
CT TCP G+ ++ + C G S S CR
Sbjct: 343 CTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCR---------- 392
Query: 99 ACCPGYWGSRCHE----CPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPN 154
C GY G C + C + +PC+ C+D D C CQ F G C + D
Sbjct: 393 -CPVGYSGFNCEKKIDYC---SSSPCSNGAKCVDLGDAY-LCRCQAGFSGRHCDDNVD-- 445
Query: 155 RFGPDCQSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEA 214
DC S G C G D SC C GYTG +C + C+ C C
Sbjct: 446 ----DCASSPCANGGTCRDGVN-DFSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHERG 500
Query: 215 PS--CRCLPGY 223
C C GY
Sbjct: 501 HRYVCECARGY 511
Score = 59.7 bits (143), Expect = 4e-08
Identities = 63/220 (28%), Positives = 80/220 (36%), Gaps = 79/220 (35%)
Query: 1369 VCELGRYGPNCTGVC---DCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCD 1425
VC+ YG C+ C D A G G +G+ VCN GW+G C T P C CD
Sbjct: 178 VCDEHYYGEGCSVFCRPRDDAFGHFTCGERGEK--VCNPGWKGPYC----TEPICLPGCD 231
Query: 1426 PNANCVQDSAGASTCACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQ 1485
HG C PG+ C C+
Sbjct: 232 EQ-----------------------------------HGFCDK--------PGE--CKCR 246
Query: 1486 DGYMGDGELCQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSG----DGIRTCELL 1541
G+ G C E I + GC +H C Q C+C+EG+ G + C
Sbjct: 247 VGWQG--RYCDEC----IRYPGC-LHGTC----QQPWQCNCQEGWGGLFCNQDLNYCTHH 295
Query: 1542 DPCSKNNGGCSPYATCKSTGDGQRTCTCDTAHTVGDGLTC 1581
PC NG ATC +TG G TC+C +T G TC
Sbjct: 296 KPCK--NG-----ATCTNTGQGSYTCSCRPGYT---GATC 325
Score = 47.0 bits (110), Expect = 2e-04
Identities = 32/104 (30%), Positives = 43/104 (41%), Gaps = 19/104 (18%)
Query: 100 CCPGYWGSRCHE-CPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGP 158
C G+ G C + A +PC GTC DG++ + +C C + G C
Sbjct: 431 CQAGFSGRHCDDNVDDCASSPCANGGTCRDGVN-DFSCTCPPGYTGRNCSA--------- 480
Query: 159 DCQSVCSCVHGVCNHGP----RGDGS-CLCFAGYTGPHCDQELP 197
V C H C++G RG C C GY GP+C LP
Sbjct: 481 ---PVSRCEHAPCHNGATCHERGHRYVCECARGYGGPNCQFLLP 521
>gi|24041035 notch 2 preproprotein [Homo sapiens]
Length = 2471
Score = 105 bits (263), Expect = 4e-22
Identities = 96/314 (30%), Positives = 119/314 (37%), Gaps = 62/314 (19%)
Query: 716 MEQGCCKGFFGPDCTQCPGGFS-------------NPCYGKGNCSDGIQGNGACLCFPDY 762
M G C G +CP GFS NPC G+C DG+ +CLC P +
Sbjct: 883 MNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGV-NTFSCLCLPGF 941
Query: 763 KGIAC-----HICSNPNKHGEQCQE-----DCGCVHGL----CDNRPG--------SGGV 800
G C S P K+G C + C C G C+N +GG
Sbjct: 942 TGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGT 1001
Query: 801 CQQG------TCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEG 854
C G C GF+G FC + +C + C CV G RC C G+ G
Sbjct: 1002 CVDGINSFSCLCPVGFTGSFCLHEINECS----SHPCLNEGTCVDGLGTYRCSCPLGYTG 1057
Query: 855 DGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGRVCVAIDECEL-DMR 913
T N CS R C CV C C GW+G V C++ R
Sbjct: 1058 KNCQ-TLVNLCS---RSPCKNKGTCVQ-KKAESQCLCPSGWAG-AYCDVPNVSCDIAASR 1111
Query: 914 GGCHTDALCSYVG----PGQSR-CTCKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRAVG 968
G + LC + G G + C C LG+ G Y +D C A N HG ATC
Sbjct: 1112 RGVLVEHLCQHSGVCINAGNTHYCQCPLGYTG-SYCEEQLDEC-ASNPCQHG-ATCSDFI 1168
Query: 969 GGQRVCTCPPGFGG 982
GG R C C PG+ G
Sbjct: 1169 GGYR-CECVPGYQG 1181
Score = 98.6 bits (244), Expect = 7e-20
Identities = 83/341 (24%), Positives = 124/341 (36%), Gaps = 40/341 (11%)
Query: 16 CLAGFSFVRGQVLFKGCDVKTTFVTHVPCTSCAAIKKQTCPSGWLRELPDQITQDCRYEV 75
CL GF+ + + CD+ C + + CP G+ + D + C
Sbjct: 170 CLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSP 229
Query: 76 QLGGSMVSMSGCRRKCRKQVVQKACCPGYWGSRCH----ECPGGAETPCNGHGTCLDGMD 131
+ G G R+ + C PG+ GS C +CP C G C+DG++
Sbjct: 230 CVNG------GTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHR---CQNGGVCVDGVN 280
Query: 132 RNGTCVCQENFRGSACQECQDPNRFGPD-CQSVCSCVHGVCNHGPRGDGSCLCFAGYTGP 190
C C + G C E D P+ CQ+ +C + +G C+C G++G
Sbjct: 281 TYN-CRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYG------CVCVNGWSGD 333
Query: 191 HCDQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQGSECRAPNPCWPSPCSLLAQCSVS 250
C + + C C + C S C+ + G C + C +PC A C +
Sbjct: 334 DCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGALCDTN 393
Query: 251 P-KGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCP-SNSTLCVY-----QKPGQAFCTCR 303
P GQ C CP+ Y G CT+++ C +NS C + G C C
Sbjct: 394 PLNGQYICTCPQGYKG--------ADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECL 445
Query: 304 PGLVSINSNASAGCFAFCSPFSCDRSATCQVTADGKTSCVC 344
G C C ATC G T C+C
Sbjct: 446 KGYAGPRCEMDIN---ECHSDPCQNDATCLDKIGGFT-CLC 482
Score = 94.7 bits (234), Expect = 1e-18
Identities = 93/306 (30%), Positives = 119/306 (38%), Gaps = 74/306 (24%)
Query: 720 CCKGFFGPDCT----QCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHI----CS 771
C KGF G +C +C SNPC +G C D I G C C Y G C CS
Sbjct: 783 CKKGFKGYNCQVNIDECA---SNPCLNQGTCFDDISGY-TCHCVLPYTGKNCQTVLAPCS 838
Query: 772 -NPNKHGEQCQED-------CGCV----------------------HGLCDNRPGSGGVC 801
NP ++ C+E C C HGLC N GS +C
Sbjct: 839 PNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSY-MC 897
Query: 802 QQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGDGFSCTP 861
+ C PGFSG C E + DC LA C C+ C CL GF GD
Sbjct: 898 E---CPPGFSGMDCEEDIDDC----LANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDM 950
Query: 862 SNPCSHPDRGG--CSENAECVPGSLGTHHCTCHKGWSGDGRVCV-AIDECELD--MRGGC 916
+ S P + G CS+ + ++ C C G+ DG C I+EC GG
Sbjct: 951 NECLSEPCKNGGTCSD-------YVNSYTCKCQAGF--DGVHCENNINECTESSCFNGGT 1001
Query: 917 HTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTC 976
D + S+ C C +GF G + I+ C + C TC G G C+C
Sbjct: 1002 CVDGINSF------SCLCPVGFTG-SFCLHEINEC--SSHPCLNEGTC-VDGLGTYRCSC 1051
Query: 977 PPGFGG 982
P G+ G
Sbjct: 1052 PLGYTG 1057
Score = 94.0 bits (232), Expect = 2e-18
Identities = 80/283 (28%), Positives = 119/283 (42%), Gaps = 45/283 (15%)
Query: 1932 HPSLWGRP-QGLGRGC-HRNCV--TTTWKPSCCPGHYGSECQACPGGP-SSPCSDRGVCM 1986
HPS + + + L C H NC + +K C G G C+ S+PC + G C
Sbjct: 714 HPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTC- 772
Query: 1987 DGMSGSGQCLCRSGFAGTACELCAPGAFGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWT 2046
D + +C C+ GF G C++ C + C G C + + G +C C +T
Sbjct: 773 DNLVNGYRCTCKKGFKGYNCQVNI-----DECASNPCLNQGTCFDDISGY-TCHCVLPYT 826
Query: 2047 GPRCEVQLELQPVCTPPCAPEAVCR-----AGNSCECSLGYEGDGRVCTVADLCQDGHGG 2101
G C Q L P PC AVC+ +C C+ G++ G+ CT+ D+ +
Sbjct: 827 GKNC--QTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQ--GQRCTI-DIDECISKP 881
Query: 2102 CSEHANCSQVGTMVTCTCLPDYEG-----DGWSCRARNPCTDGHRGGCSEHANCLSTGLN 2156
C H C C C P + G D C A NPC +G G C + G+N
Sbjct: 882 CMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLA-NPCQNG--GSCMD-------GVN 931
Query: 2157 TRRCECHAGYVGDGLQCLEESEPPVDRCLGQPPPCHSDAMCTD 2199
T C C G+ GD + + ++ CL + PC + C+D
Sbjct: 932 TFSCLCLPGFTGD------KCQTDMNECLSE--PCKNGGTCSD 966
Score = 92.0 bits (227), Expect = 7e-18
Identities = 77/258 (29%), Positives = 106/258 (41%), Gaps = 55/258 (21%)
Query: 720 CCKGFFGPDCT-QCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGE 778
C G+ G C+ Q +S+PC G C D + G C C P G+ C I + +
Sbjct: 595 CNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGY-QCNCQPGTSGVNCEI------NFD 647
Query: 779 QCQEDCGCVHGLCDNRPGSGGVCQQG-TCAPGFSGRFCNESMGDCGPTGLAQHCHLHARC 837
C + C+HG+C + G+ + C+PGF+G+ CN + +C + C A C
Sbjct: 648 DCASN-PCIHGICMD-----GINRYSCVCSPGFTGQRCNIDIDECA----SNPCRKGATC 697
Query: 838 VSQEGVARCRCLDGFEGDGFSCTP------SNPCSHPDRGGCSENAECVPGSLGTHHCTC 891
++ RC C +G SC SNPC H G C+ G L + C C
Sbjct: 698 INGVNGFRCICPEGPHHP--SCYSQVNECLSNPCIH---GNCT-------GGLSGYKCLC 745
Query: 892 HKGWSGDGRVCVAIDECELD----MRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCS- 946
GW G CE+D + C C + G RCTCK GF GY C
Sbjct: 746 DAGWVGIN--------CEVDKNECLSNPCQNGGTCDNLVNGY-RCTCKKGF--KGYNCQV 794
Query: 947 PIDPCRAGNGGCHGLATC 964
ID C + C TC
Sbjct: 795 NIDEC--ASNPCLNQGTC 810
Score = 91.7 bits (226), Expect = 9e-18
Identities = 100/351 (28%), Positives = 133/351 (37%), Gaps = 69/351 (19%)
Query: 1247 IGLSGVLTVGSSRCLHSHAEALREKCVNCTRRF--RCTQGFQLQ--DTPRKSC-----VY 1297
+G +G + CL SH A C +F +C GF Q +T C
Sbjct: 135 VGFTGKECQWTDACL-SHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQ 193
Query: 1298 RSGFSFSRGCSYTCAKKIQVPDCCPGFFGTLCE----PCPGGLGGVCSGHGQCQDRFLGS 1353
G + SY C C GF G C+ PC C G C+ +
Sbjct: 194 HGGTCLNLPGSYQC-------QCPQGFTGQYCDSLYVPCAPS---PCVNGGTCRQTGDFT 243
Query: 1354 GECHCHEGFHGTACEVCELGRYGPNCTGVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQ 1413
EC+C GF G+ CE + DC + CQ G G CV V RC
Sbjct: 244 FECNCLPGFEGSTCE-----------RNIDDCPNHRCQNG----GVCVDGVNTYNCRCPP 288
Query: 1414 KITSPQC----------PRKCDPNANCVQDSAGASTCACAAGYSGNGIFCSE-VDPCAHG 1462
+ T C P C C + G C C G+SG+ CSE +D CA
Sbjct: 289 QWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYG-CVCVNGWSGDD--CSENIDDCA-- 343
Query: 1463 HGGCSPHANC-TKVAPGQRTCTCQDGYMGDGELCQEINSCLIHHGGCHIHAECIPTGP-- 1519
C+P + C +VA +C C +G G LC ++C+ CH A C T P
Sbjct: 344 FASCTPGSTCIDRVA--SFSCMCPEGKA--GLLCHLDDACI--SNPCHKGALC-DTNPLN 396
Query: 1520 QQVSCSCREGYSGDGIRTCELLDPCS-KNNGGCSPYATCKSTGDGQRTCTC 1569
Q C+C +GY G E +D C+ N+ C C +T DG C C
Sbjct: 397 GQYICTCPQGYK--GADCTEDVDECAMANSNPCEHAGKCVNT-DGAFHCEC 444
Score = 87.0 bits (214), Expect = 2e-16
Identities = 76/256 (29%), Positives = 103/256 (40%), Gaps = 39/256 (15%)
Query: 1340 CSGHGQCQDRFLGSGECHCHEGFHGTAC---EVCELGRYGPNCTGVCDCAHGLCQEGLQG 1396
C G C G+G C C EGF G C + CE R C + + G
Sbjct: 35 CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNR--------CQNGGTCVAQAMLG 86
Query: 1397 DGSCVCNVGWQGLRCDQKITSPQC--PRKCDPNANCVQDSAGASTCACAAGYSGNGIFCS 1454
+C C G+ G C Q TS C R C C S C C G++G C
Sbjct: 87 KATCRCASGFTGEDC-QYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKE--CQ 143
Query: 1455 EVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQ-EINSCLIHHGGCHIHAE 1513
D C C+ + CT VA Q +C C G+ G+ C+ ++N C I G C
Sbjct: 144 WTDACL--SHPCANGSTCTTVA-NQFSCKCLTGF--TGQKCETDVNECDI-PGHCQHGGT 197
Query: 1514 CIPTGPQQVSCSCREGYSGDGIRTCE-LLDPCSKN---NGGCSPYATCKSTGDGQRTCTC 1569
C+ P C C +G++G + C+ L PC+ + NGG TC+ TGD C C
Sbjct: 198 CLNL-PGSYQCQCPQGFTG---QYCDSLYVPCAPSPCVNGG-----TCRQTGDFTFECNC 248
Query: 1570 DTAHTVGDGLTCRARV 1585
+G TC +
Sbjct: 249 LPGF---EGSTCERNI 261
Score = 87.0 bits (214), Expect = 2e-16
Identities = 84/293 (28%), Positives = 117/293 (39%), Gaps = 61/293 (20%)
Query: 100 CCPGYWGSRC----HECPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNR 155
C GY G+ C EC PC G C++ D C C + + G C+ D N
Sbjct: 403 CPQGYKGADCTEDVDECAMANSNPCEHAGKCVN-TDGAFHCECLKGYAGPRCE--MDINE 459
Query: 156 FGPD-CQSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQELPVCQELRCPQNTQC--SA 212
D CQ+ +C+ + G +CLC G+ G HC+ E+ CQ C N QC
Sbjct: 460 CHSDPCQNDATCLDKI------GGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKV 513
Query: 213 EAPSCRCLPGYTQQGSECRAP-NPCWPSPCSLLAQCSVSPKG-QAQCH-------CPEN- 262
C C PG+T G C+ + C +PC A+C P G + QC C EN
Sbjct: 514 NRFQCLCPPGFT--GPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENI 571
Query: 263 --------YHG---DGM-----VCLP---KDPCTDNLGGCPSNSTL----CVYQKPGQAF 299
+HG DG+ +C P C+D + C S+ L C+ G
Sbjct: 572 DNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQ- 630
Query: 300 CTCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVTADG--KTSCVCRESEVG 350
C C+PG +N + F C+ C + DG + SCVC G
Sbjct: 631 CNCQPGTSGVNCEIN---FDDCASNPCIHG----ICMDGINRYSCVCSPGFTG 676
Score = 85.9 bits (211), Expect = 5e-16
Identities = 92/333 (27%), Positives = 123/333 (36%), Gaps = 54/333 (16%)
Query: 662 VAGSCVDCQALNTSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKGCASYCNQTIMEQGCC 721
+ G C+D + C P + C D N +KG C
Sbjct: 655 IHGICMDGINRYSCVCSPGFTG-----QRCNIDIDECASNPCRKGATCINGVNGFRCICP 709
Query: 722 KGFFGPDC-TQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHI-----CSNPNK 775
+G P C +Q SNPC GNC+ G+ G CLC + GI C + SNP +
Sbjct: 710 EGPHHPSCYSQVNECLSNPCI-HGNCTGGLSGY-KCLCDAGWVGINCEVDKNECLSNPCQ 767
Query: 776 HGEQCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHA 835
+G G CDN +G C TC GF G C ++ +C + C
Sbjct: 768 NG-----------GTCDNLV-NGYRC---TCKKGFKGYNCQVNIDECA----SNPCLNQG 808
Query: 836 RCVSQEGVARCRCLDGFEGDGFS-----CTPSNPCSHPDRGGCSENAECVPGSLGTHHCT 890
C C C+ + G C+P NPC + C E+ + ++ C
Sbjct: 809 TCFDDISGYTCHCVLPYTGKNCQTVLAPCSP-NPCENA--AVCKESP-----NFESYTCL 860
Query: 891 CHKGWSGDGRVCVAIDECELDMRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDP 950
C GW G R + IDEC + C LC G C C GF+G + ID
Sbjct: 861 CAPGWQGQ-RCTIDIDEC---ISKPCMNHGLCHNT-QGSYMCECPPGFSGMDCE-EDIDD 914
Query: 951 CRAGNGGCHGLATCRAVGGGQRVCTCPPGFGGD 983
C A C +C G C C PGF GD
Sbjct: 915 CLANP--CQNGGSCMD-GVNTFSCLCLPGFTGD 944
Score = 85.5 bits (210), Expect = 6e-16
Identities = 98/373 (26%), Positives = 130/373 (34%), Gaps = 60/373 (16%)
Query: 664 GSCVDCQALNTSTCPPNSVKLDIFPKECVY-IHDPTGLN--VLKKGCASYCNQTIMEQGC 720
G+CV L +TC S ++C Y P ++ L G ++ E C
Sbjct: 77 GTCVAQAMLGKATCRCAS---GFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTC 133
Query: 721 CKGFFGPDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHI----CSNPN-- 774
GF G +C S+PC C+ + +C C + G C C P
Sbjct: 134 QVGFTGKECQWTDACLSHPCANGSTCTT-VANQFSCKCLTGFTGQKCETDVNECDIPGHC 192
Query: 775 KHGEQCQE-----DCGCVHGL----CDN-----RPG---SGGVCQQG-------TCAPGF 810
+HG C C C G CD+ P +GG C+Q C PGF
Sbjct: 193 QHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGF 252
Query: 811 SGRFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGDGFSCTPSNPCSHPDR 870
G C ++ DC C CV CRC + G CT
Sbjct: 253 EGSTCERNIDDCP----NHRCQNGGVCVDGVNTYNCRCPPQWTGQ--FCTEDVDECLLQP 306
Query: 871 GGCSENAECVPGSLGTHHCTCHKGWSGDGRVCVAIDECELD--MRGGCHTDALCSYVGPG 928
C C + G + C C GWSGD ID+C G D + S+
Sbjct: 307 NACQNGGTCANRN-GGYGCVCVNGWSGDD-CSENIDDCAFASCTPGSTCIDRVASF---- 360
Query: 929 QSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRAVG-GGQRVCTCPPGFGGDGFSC 987
C C G A G C D C + CH A C GQ +CTCP G+ G C
Sbjct: 361 --SCMCPEGKA--GLLCHLDDACI--SNPCHKGALCDTNPLNGQYICTCPQGY--KGADC 412
Query: 988 YGDIFRELEANAH 1000
D+ AN++
Sbjct: 413 TEDVDECAMANSN 425
Score = 85.5 bits (210), Expect = 6e-16
Identities = 80/333 (24%), Positives = 116/333 (34%), Gaps = 100/333 (30%)
Query: 1943 GRGCHRNCVTTTWKPSCCPGHYGSEC----QACPGGPSSPCSDRGVCMDGMSGSGQCLCR 1998
G C N + + +C G+ G++C C S+PC G C++ G+ C C
Sbjct: 387 GALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVN-TDGAFHCECL 445
Query: 1999 SGFAGTACE--------------------------LCAPGAFGPHC-------QACRCTV 2025
G+AG CE LC PG G HC Q+ C
Sbjct: 446 KGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVN 505
Query: 2026 HGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEAVC---RAGNSCECSLGY 2082
+G+C + + C C G+TGP C Q+++ + PC A C G C+C+ G+
Sbjct: 506 NGQCVDKVNRF-QCLCPPGFTGPVC--QIDIDDCSSTPCLNGAKCIDHPNGYECQCATGF 562
Query: 2083 EGDGRVCTVADLCQDGHGGCS----EHANCSQVGTMVTCTCLPDYEG------------- 2125
G LC++ C H C TC C P Y G
Sbjct: 563 TG--------VLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSS 614
Query: 2126 ------------DGWSCRARNPCTDG-----HRGGCSE----HANCLSTGLNTRRCECHA 2164
+G+ C + P T G + C+ H C+ G+N C C
Sbjct: 615 PCLNDGRCIDLVNGYQCNCQ-PGTSGVNCEINFDDCASNPCIHGICMD-GINRYSCVCSP 672
Query: 2165 GYVGDGLQCLEESEPPVDRCLGQPPPCHSDAMC 2197
G+ G + +D C PC A C
Sbjct: 673 GFTG------QRCNIDIDECASN--PCRKGATC 697
Score = 85.5 bits (210), Expect = 6e-16
Identities = 89/309 (28%), Positives = 118/309 (38%), Gaps = 68/309 (22%)
Query: 720 CCKGFFGPDC----TQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHI----C- 770
C KG+ GP C +C S+PC C D I G CLC P +KG+ C + C
Sbjct: 444 CLKGYAGPRCEMDINEC---HSDPCQNDATCLDKI-GGFTCLCMPGFKGVHCELEINECQ 499
Query: 771 SNPNKHGEQCQEDCGCVHGLCDNRPG-SGGVCQ------------------------QGT 805
SNP + QC + LC PG +G VCQ +
Sbjct: 500 SNPCVNNGQCVDKVNRFQCLCP--PGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQ 557
Query: 806 CAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGDGFSCTPSNPC 865
CA GF+G C E++ +C P CH H +C C C G+ G S
Sbjct: 558 CATGFTGVLCEENIDNCDP----DPCH-HGQCQDGIDSYTCICNPGYMGAICSDQIDECY 612
Query: 866 SHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGRVC-VAIDECELD--MRGGCHTDALC 922
S P C + C+ + + C C G SG C + D+C + + G C
Sbjct: 613 SSP----CLNDGRCI-DLVNGYQCNCQPGTSGVN--CEINFDDCASNPCIHGICMD---- 661
Query: 923 SYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGFGG 982
G + C C GF G +C+ ID + C ATC G R C CP G
Sbjct: 662 ---GINRYSCVCSPGFTGQ--RCN-IDIDECASNPCRKGATCINGVNGFR-CICPE--GP 712
Query: 983 DGFSCYGDI 991
SCY +
Sbjct: 713 HHPSCYSQV 721
Score = 84.3 bits (207), Expect = 1e-15
Identities = 106/420 (25%), Positives = 142/420 (33%), Gaps = 56/420 (13%)
Query: 30 KGCDVKTTFVTHVPCTS---CAAIKKQT---CPSGWLRELPDQITQDCRYEVQLGGSMVS 83
K C + PC + C K ++ CPSGW D C G +V
Sbjct: 1058 KNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVE 1117
Query: 84 MSGCRRK--CRKQVVQKAC-CP-GYWGSRCHE-CPGGAETPCNGHGTCLDGMDRNGTCVC 138
C+ C C CP GY GS C E A PC TC D + C C
Sbjct: 1118 HL-CQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIG-GYRCEC 1175
Query: 139 QENFRGSACQ----ECQDPNRFGPDCQSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQ 194
++G C+ ECQ+ CQ+ +C+ + NH C C G G C++
Sbjct: 1176 VPGYQGVNCEYEVDECQN-----QPCQNGGTCI-DLVNH-----FKCSCPPGTRGLLCEE 1224
Query: 195 ELPVC-QELRCPQNTQCSAE--APSCRCLPGYTQQGSECRAP-NPCWPSPCSLLAQCS-V 249
+ C + C QC SCRCLPG+ G C N C +PCS +
Sbjct: 1225 NIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFA--GERCEGDINECLSNPCSSEGSLDCI 1282
Query: 250 SPKGQAQCHCPENYHGDGM-----VCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRP 304
C C + G VC P+ PC N G C S + P C C P
Sbjct: 1283 QLTNDYLCVCRSAFTGRHCETFVDVC-PQMPCL-NGGTCAVASNM-----PDGFICRCPP 1335
Query: 305 GLVSINSNASAGCFAFCSPFSCDRSATCQVTADGKTSCVCRESEVGDGRACYGHLLHEVQ 364
G + A C + C C + C TA G C C + H
Sbjct: 1336 GF------SGARCQSSCGQVKCRKGEQCVHTASG-PRCFCPSPRDCESGCASSPCQHGGS 1388
Query: 365 KATQTGRVFLQLRVAVAMMDQGCREILTTAGPFTVLVPSVSSFSSRTMNASLAQQLCRQH 424
Q + + A C L TA P T +S + + + + C H
Sbjct: 1389 CHPQRQPPYYSCQCAPPFSGSRCE--LYTAPPSTPPATCLSQYCADKARDGVCDEACNSH 1446
Score = 84.0 bits (206), Expect = 2e-15
Identities = 93/305 (30%), Positives = 120/305 (39%), Gaps = 60/305 (19%)
Query: 1932 HPSLWGRPQGLGRGCHRNCVTTTWKPSCCPGHYGSECQACPGGPSSPCSDRGVCMDGMSG 1991
HP RP G CH T++ +C G G ECQ S PC++ C ++
Sbjct: 107 HPCFVSRPCLNGGTCHM-LSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTT-VAN 164
Query: 1992 SGQCLCRSGFAGTACELCAPGAFGP-HCQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRC 2050
C C +GF G CE P HCQ HG L GS C C +G+TG C
Sbjct: 165 QFSCKCLTGFTGQKCETDVNECDIPGHCQ------HGGTCLNLPGSYQCQCPQGFTGQYC 218
Query: 2051 EVQLELQPVCTP-PCAPEAVCRAGN----SCECSLGYEGDGRVCTVADL----CQDGHGG 2101
+ L C P PC CR C C G+EG + D CQ+G G
Sbjct: 219 D---SLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNG-GV 274
Query: 2102 CSEHAN-----CSQVGTMVTCT-----CL--PDYEGDGWSCRARN-----PCTDGHRG-G 2143
C + N C T CT CL P+ +G +C RN C +G G
Sbjct: 275 CVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDD 334
Query: 2144 CSEH------ANCL--STGLN---TRRCECHAGYVGDGLQCLEESEPPVDRCLGQPPPCH 2192
CSE+ A+C ST ++ + C C G GL C + D C+ PCH
Sbjct: 335 CSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKA--GLLCHLD-----DACISN--PCH 385
Query: 2193 SDAMC 2197
A+C
Sbjct: 386 KGALC 390
Score = 83.2 bits (204), Expect = 3e-15
Identities = 52/196 (26%), Positives = 78/196 (39%), Gaps = 19/196 (9%)
Query: 1978 PCSDRGVCMDGMSGSGQCLCRSGFAGTACELCAPGAFGPHCQACRCTVHGRC-DEGLGGS 2036
PC + G+C+ +G+G C C GF G C+ P C+ RC G C + + G
Sbjct: 34 PCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDP------CEKNRCQNGGTCVAQAMLGK 87
Query: 2037 GSCFCDEGWTGPRCEVQLELQPVCTPPCAPEAVC----RAGNSCECSLGYEGDGRVCTVA 2092
+C C G+TG C+ + PC C R C C +G+ G+ C
Sbjct: 88 ATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGF--TGKECQWT 145
Query: 2093 DLCQDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWSCRARNPCTDGHRGGCSEHANCLS 2152
D C C+ + C+ V +C CL + G GH C CL+
Sbjct: 146 DACLS--HPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGH---CQHGGTCLN 200
Query: 2153 TGLNTRRCECHAGYVG 2168
+ +C+C G+ G
Sbjct: 201 LP-GSYQCQCPQGFTG 215
Score = 83.2 bits (204), Expect = 3e-15
Identities = 72/260 (27%), Positives = 99/260 (38%), Gaps = 34/260 (13%)
Query: 1954 TWKPSCCPGHYGSECQACPGGPS-SPCSDRGVCMDGMSGSGQCLCRSGFAGTACEL---- 2008
T++ SC G+ G CQ S SPC ++G C+ + S QCLC SG+AG C++
Sbjct: 1046 TYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAES-QCLCPSGWAGAYCDVPNVS 1104
Query: 2009 CAPGAFGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEA 2068
C A H G + C C G+TG CE QL+ + PC A
Sbjct: 1105 CDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLD--ECASNPCQHGA 1162
Query: 2069 VCR---AGNSCECSLGYEGDGRVCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPDYEG 2125
C G CEC GY+G V D CQ + C C + C+C P
Sbjct: 1163 TCSDFIGGYRCECVPGYQGVNCEYEV-DECQ--NQPCQNGGTCIDLVNHFKCSCPPG--- 1216
Query: 2126 DGWSCRARNPCTDGHRGGCSEHANCLSTG-----LNTRRCECHAGYVGDGLQCLEESEPP 2180
R + + C+ +CL+ G + C C G+ G E E
Sbjct: 1217 ------TRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAG------ERCEGD 1264
Query: 2181 VDRCLGQPPPCHSDAMCTDL 2200
++ CL P C L
Sbjct: 1265 INECLSNPCSSEGSLDCIQL 1284
Score = 82.8 bits (203), Expect = 4e-15
Identities = 70/240 (29%), Positives = 96/240 (40%), Gaps = 36/240 (15%)
Query: 100 CCPGYWGSRCHE-CPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGP 158
C PG+ G C E PC G+C+DG++ +C+C F G CQ + P
Sbjct: 899 CPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVN-TFSCLCLPGFTGDKCQTDMNECLSEP 957
Query: 159 DCQSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQELPVCQELRCPQNTQC--SAEAPS 216
C++ +C V ++ +C C AG+ G HC+ + C E C C + S
Sbjct: 958 -CKNGGTCSDYVNSY------TCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFS 1010
Query: 217 CRCLPGYTQQGSEC-RAPNPCWPSPCSLLAQCSVSPKGQAQCHCPENYHGDGMVCL---- 271
C C G+T GS C N C PC C V G +C CP Y G L
Sbjct: 1011 CLCPVGFT--GSFCLHEINECSSHPCLNEGTC-VDGLGTYRCSCPLGYTGKNCQTLVNLC 1067
Query: 272 PKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPGLVSINSNASAGCFAFCSPFSCDRSAT 331
+ PC N CV QK ++ C C G AG + SCD +A+
Sbjct: 1068 SRSPC--------KNKGTCV-QKKAESQCLCPSGW--------AGAYCDVPNVSCDIAAS 1110
Score = 82.0 bits (201), Expect = 7e-15
Identities = 95/345 (27%), Positives = 120/345 (34%), Gaps = 82/345 (23%)
Query: 664 GSCVDCQALNTSTCPPN--SVKLDIFPKECVYIHDPTGLNV----------LKKGCASYC 711
G+CV +A + CP D+ C G+ V + G YC
Sbjct: 1076 GTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYC 1135
Query: 712 NQTIMEQGCCKGFFGPDCT-QCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHI- 769
C G+ G C Q SNPC CSD I G C C P Y+G+ C
Sbjct: 1136 Q-------CPLGYTGSYCEEQLDECASNPCQHGATCSDFI-GGYRCECVPGYQGVNCEYE 1187
Query: 770 ---CSNPNKHGEQCQEDCGCV----HGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDC 822
C N + CQ C+ H C +C PG G C E++ DC
Sbjct: 1188 VDECQN-----QPCQNGGTCIDLVNHFKC-------------SCPPGTRGLLCEENIDDC 1229
Query: 823 --GPTGLAQHCHLHARCVSQEGVARCRCLDGF-----EGDGFSCTPSNPCSHPDRGGCSE 875
GP HC +C+ + G CRCL GF EGD C SNPCS C +
Sbjct: 1230 ARGP-----HCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECL-SNPCSSEGSLDCIQ 1283
Query: 876 NAECVPGSLGTHHCTCHKGWSGDGRVC-VAIDECELDMRGGCHTDALCSYVG--PGQSRC 932
+ C C ++ GR C +D C + C C+ P C
Sbjct: 1284 -------LTNDYLCVCRSAFT--GRHCETFVDVCP---QMPCLNGGTCAVASNMPDGFIC 1331
Query: 933 TCKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCP 977
C GF+G Q S G C C G R C CP
Sbjct: 1332 RCPPGFSGARCQSS------CGQVKCRKGEQCVHTASGPR-CFCP 1369
Score = 81.3 bits (199), Expect = 1e-14
Identities = 70/249 (28%), Positives = 98/249 (39%), Gaps = 41/249 (16%)
Query: 1959 CCPGHYGSECQA-CPGGPSSPCSDRGVCMDGMSGSGQCLCRSGFAGTACELCAPGAFGPH 2017
C PG G C S PC + G+C + GS C C GF+G CE
Sbjct: 861 CAPGWQGQRCTIDIDECISKPCMNHGLCHN-TQGSYMCECPPGFSGMDCEEDIDD----- 914
Query: 2018 CQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEAVCRA---GN 2074
C A C G C +G+ + SC C G+TG +C Q ++ + PC C
Sbjct: 915 CLANPCQNGGSCMDGVN-TFSCLCLPGFTGDKC--QTDMNECLSEPCKNGGTCSDYVNSY 971
Query: 2075 SCECSLGYEGDGRVCTVADLCQDGHGGCSEHANCSQVGTMV------TCTCLPDYEGDGW 2128
+C+C G++G C++ C+E ++C GT V +C C + G +
Sbjct: 972 TCKCQAGFDGVH--------CENNINECTE-SSCFNGGTCVDGINSFSCLCPVGFTGS-F 1021
Query: 2129 SCRARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGDGLQCLEESEPPVDRCLGQP 2188
N C+ C C+ GL T RC C GY G Q L V+ C
Sbjct: 1022 CLHEINECSSHP---CLNEGTCVD-GLGTYRCSCPLGYTGKNCQTL------VNLC--SR 1069
Query: 2189 PPCHSDAMC 2197
PC + C
Sbjct: 1070 SPCKNKGTC 1078
Score = 80.9 bits (198), Expect = 2e-14
Identities = 75/261 (28%), Positives = 96/261 (36%), Gaps = 62/261 (23%)
Query: 765 IACHICSNPNKHGEQCQEDCG-CVH-GLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDC 822
+A +C H QC++ CV+ G+C G C+ C GF G +C + C
Sbjct: 13 LALWLCCAAPAHALQCRDGYEPCVNEGMCVTYHNGTGYCK---CPEGFLGEYC-QHRDPC 68
Query: 823 GPTGLAQHCHLHARCVSQE--GVARCRCLDGFEGDGFSCTPSNPC--SHPDRGGCSENAE 878
C CV+Q G A CRC GF G+ + S+PC S P C
Sbjct: 69 EKN----RCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRP----CLNGGT 120
Query: 879 CVPGSLGTHHCTCHKGWSG---------------DGRVCVAI------------------ 905
C S T+ CTC G++G +G C +
Sbjct: 121 CHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCE 180
Query: 906 -DECELDMRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAG---NGGCHGL 961
D E D+ G C C + PG +C C GF G Y S PC NGG
Sbjct: 181 TDVNECDIPGHCQHGGTCLNL-PGSYQCQCPQGFTGQ-YCDSLYVPCAPSPCVNGG---- 234
Query: 962 ATCRAVGGGQRVCTCPPGFGG 982
TCR G C C PGF G
Sbjct: 235 -TCRQTGDFTFECNCLPGFEG 254
Score = 79.7 bits (195), Expect = 3e-14
Identities = 69/242 (28%), Positives = 93/242 (38%), Gaps = 28/242 (11%)
Query: 111 ECPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDP---NRFGPDCQSVCSCV 167
+C G E PC G C+ + G C C E F G CQ +DP NR CQ+ +CV
Sbjct: 27 QCRDGYE-PCVNEGMCVTYHNGTGYCKCPEGFLGEYCQH-RDPCEKNR----CQNGGTCV 80
Query: 168 HGVCNHGPRGDGSCLCFAGYTGPHCDQEL--PVCQELRCPQNTQC---SAEAPSCRCLPG 222
G +C C +G+TG C P C C S + C C G
Sbjct: 81 ----AQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVG 136
Query: 223 YTQQGSECRAPNPCWPSPCSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGG 282
+T G EC+ + C PC+ + C+ + Q C C + G C D G
Sbjct: 137 FT--GKECQWTDACLSHPCANGSTCT-TVANQFSCKCLTGF--TGQKCETDVNECDIPGH 191
Query: 283 CPSNSTLCVYQKPGQAFCTCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVTADGKTSC 342
C T C+ PG C C G ++ + C+P C TC+ T D C
Sbjct: 192 CQHGGT-CL-NLPGSYQCQCPQGFTGQYCDS---LYVPCAPSPCVNGGTCRQTGDFTFEC 246
Query: 343 VC 344
C
Sbjct: 247 NC 248
Score = 79.0 bits (193), Expect = 6e-14
Identities = 79/277 (28%), Positives = 102/277 (36%), Gaps = 36/277 (12%)
Query: 1320 CCPGFFGTLCEPCPGG-LGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPN 1378
C PGF G C+ L C G C D ++ S C C GF G CE
Sbjct: 937 CLPGFTGDKCQTDMNECLSEPCKNGGTCSD-YVNSYTCKCQAGFDGVHCE-----NNINE 990
Query: 1379 CTGVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQC-PRKCDPNANCVQDSAGA 1437
CT G C +G+ SC+C VG+ G C +I +C C CV D G
Sbjct: 991 CTESSCFNGGTCVDGINSF-SCLCPVGFTGSFCLHEIN--ECSSHPCLNEGTCV-DGLGT 1046
Query: 1438 STCACAAGYSGNGIFCSE-VDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMG------ 1490
C+C GY+G C V+ C+ C C + + C C G+ G
Sbjct: 1047 YRCSCPLGYTGKN--CQTLVNLCS--RSPCKNKGTCVQ-KKAESQCLCPSGWAGAYCDVP 1101
Query: 1491 --DGELCQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLDPCSKNN 1548
++ L+ H C CI G C C GY+G E LD C+ N
Sbjct: 1102 NVSCDIAASRRGVLVEH-LCQHSGVCINAGNTHY-CQCPLGYTGSYCE--EQLDECASN- 1156
Query: 1549 GGCSPYATCKSTGDGQRTCTCDTAHTVGDGLTCRARV 1585
C ATC G R C C + G+ C V
Sbjct: 1157 -PCQHGATCSDFIGGYR-CECVPGY---QGVNCEYEV 1188
Score = 77.8 bits (190), Expect = 1e-13
Identities = 97/358 (27%), Positives = 129/358 (36%), Gaps = 70/358 (19%)
Query: 1258 SRCLHSHAEALREKCVN---C-----TRRFRCTQGFQLQDTPRKSCVYRSGFSFSRGCSY 1309
S CLH E C+N C T R C G+ K+C C
Sbjct: 1020 SFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYT-----GKNCQTLVNLCSRSPCKN 1074
Query: 1310 --TCAKKIQVPDC-CP-GFFGTLCE------PCPGGLGGV-----CSGHGQCQDRFLGSG 1354
TC +K C CP G+ G C+ GV C G C + +G
Sbjct: 1075 KGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVC----INAG 1130
Query: 1355 E---CHCHEGFHGTACEVCELGRYGPNCTGVCDCAHGLCQEGLQGDGSCVCNVGWQGLRC 1411
C C G+ G+ CE +L N C HG G C C G+QG+ C
Sbjct: 1131 NTHYCQCPLGYTGSYCEE-QLDECASN-----PCQHGATCSDFIGGYRCECVPGYQGVNC 1184
Query: 1412 DQKITSPQCPRKCDPNANCVQDSAGASTCACAAGYSGNGIFCSE-VDPCAHGHGGCSPHA 1470
+ ++ Q + C C+ D C+C G G+ C E +D CA G C
Sbjct: 1185 EYEVDECQ-NQPCQNGGTCI-DLVNHFKCSCPPG--TRGLLCEENIDDCARG-PHCLNGG 1239
Query: 1471 NCTKVAPGQRTCTCQDGYMGDGELCQ-EINSCLIHHGGCHIHAECIPTGPQQVSCSCREG 1529
C G +C C G+ GE C+ +IN CL + +CI C CR
Sbjct: 1240 QCMDRIGGY-SCRCLPGFA--GERCEGDINECLSNPCSSEGSLDCIQL-TNDYLCVCRSA 1295
Query: 1530 YSGDGIRTCE-LLDPCSKNNGGCSPYATCKSTGDGQRTCTCDTAHTVGDGLTCRARVG 1586
++G R CE +D C P C + G TC A + DG CR G
Sbjct: 1296 FTG---RHCETFVDVC--------PQMPCLNGG------TCAVASNMPDGFICRCPPG 1336
Score = 77.4 bits (189), Expect = 2e-13
Identities = 86/368 (23%), Positives = 135/368 (36%), Gaps = 67/368 (18%)
Query: 16 CLAGFSFVRGQVLFKGCDVKTTFVTHVPCTSCAAIKKQTCPSGWLRELPDQITQDCRYEV 75
C+ GF V ++ C V + C + CP G+ + C+ ++
Sbjct: 482 CMPGFKGVHCELEINECQ-SNPCVNNGQCVDKVNRFQCLCPPGFTGPV-------CQIDI 533
Query: 76 QLGGSMVSMSGCRRKCRKQVVQKACCPGYWGSRCHECPGGAET-PCNGHGTCLDGMDRNG 134
S ++G + + C G+ G C E + PC+ HG C DG+D +
Sbjct: 534 DDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCH-HGQCQDGID-SY 591
Query: 135 TCVCQENFRGSACQE--------------------------CQDPNRFGPDCQ---SVCS 165
TC+C + G+ C + CQ P G +C+ C+
Sbjct: 592 TCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQ-PGTSGVNCEINFDDCA 650
Query: 166 ---CVHGVCNHGPRGDGSCLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAPSCRCLPG 222
C+HG+C G SC+C G+TG C+ ++ C C + C RC+
Sbjct: 651 SNPCIHGICMDGINRY-SCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICP 709
Query: 223 YTQQGSECRAP-NPCWPSPCSLLAQCSVSPKGQAQCHCPENYHG-----DGMVCLPKDPC 276
C + N C +PC + C+ G +C C + G D CL +PC
Sbjct: 710 EGPHHPSCYSQVNECLSNPC-IHGNCTGGLSGY-KCLCDAGWVGINCEVDKNECL-SNPC 766
Query: 277 TDNLGGCPSNSTLCVYQKPGQAFCTCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVTA 336
N G C ++ + Y+ CTC+ G N + C+ C TC
Sbjct: 767 -QNGGTC--DNLVNGYR------CTCKKGFKGYNCQVN---IDECASNPCLNQGTCFDDI 814
Query: 337 DGKTSCVC 344
G T C C
Sbjct: 815 SGYT-CHC 821
Score = 77.0 bits (188), Expect = 2e-13
Identities = 91/356 (25%), Positives = 120/356 (33%), Gaps = 74/356 (20%)
Query: 44 CTSCAAIKKQTC--PSGWLRELPDQITQDCRYEVQL----------GGSMVSMSGCRRKC 91
C + A + K TC SG+ E DC+Y GG+ +S +C
Sbjct: 79 CVAQAMLGKATCRCASGFTGE-------DCQYSTSHPCFVSRPCLNGGTCHMLSRDTYEC 131
Query: 92 RKQVVQKACCPGYWGSRCHECPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQECQ 151
QV G+ G C PC TC + +C C F G C+
Sbjct: 132 TCQV-------GFTGKECQWTDACLSHPCANGSTCTT-VANQFSCKCLTGFTGQKCE--T 181
Query: 152 DPNRFGPDCQSVCSCVH-GVCNHGPRGDGSCLCFAGYTGPHCDQELPVCQELRCPQNTQC 210
D N +C C H G C + P G C C G+TG +CD C C C
Sbjct: 182 DVN----ECDIPGHCQHGGTCLNLP-GSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTC 236
Query: 211 SAEAP---SCRCLPGYTQQGSEC-RAPNPCWPSPCSLLAQCSVSPKGQAQCHCPENYHG- 265
C CLPG+ +GS C R + C C C V C CP + G
Sbjct: 237 RQTGDFTFECNCLPGF--EGSTCERNIDDCPNHRCQNGGVC-VDGVNTYNCRCPPQWTGQ 293
Query: 266 ----DGMVCLPKDPCTDNLGGCPSNS----TLCVYQKPGQ---------AFCTCRPGLVS 308
D CL + N G C + + +CV G AF +C PG
Sbjct: 294 FCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTC 353
Query: 309 INSNASAGCFA-------------FCSPFSCDRSATCQVT-ADGKTSCVCRESEVG 350
I+ AS C C C + A C +G+ C C + G
Sbjct: 354 IDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKG 409
Score = 77.0 bits (188), Expect = 2e-13
Identities = 75/290 (25%), Positives = 109/290 (37%), Gaps = 34/290 (11%)
Query: 707 CASYCNQTIMEQGCCKGFFGPDCTQCPGGFSNPC---YGKGNCSDGIQGNGACLCFPD-- 761
C ++ +++ C+ G C GG+ C + +CS+ I C P
Sbjct: 295 CTEDVDECLLQPNACQN--GGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGST 352
Query: 762 -YKGIACHICSNPN-KHGEQCQEDCGCVHG------LCDNRPGSGG-VCQQGTCAPGFSG 812
+A C P K G C D C+ LCD P +G +C TC G+ G
Sbjct: 353 CIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYIC---TCPQGYKG 409
Query: 813 RFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGDGFSCTPSNPCSHPDRGG 872
C E + +C + C +CV+ +G C CL G+ G + S P
Sbjct: 410 ADCTEDVDECAMAN-SNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDP---- 464
Query: 873 CSENAECVPGSLGTHHCTCHKGWSGDGRVCVAIDECELDMRGGCHTDALCSYVGPGQSRC 932
C +A C+ +G C C G+ G + I+EC+ C + C + +C
Sbjct: 465 CQNDATCL-DKIGGFTCLCMPGFKG-VHCELEINECQ---SNPCVNNGQC-VDKVNRFQC 518
Query: 933 TCKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGFGG 982
C GF G Q ID C + C A C G C C GF G
Sbjct: 519 LCPPGFTGPVCQID-IDDC--SSTPCLNGAKCIDHPNGYE-CQCATGFTG 564
Score = 76.3 bits (186), Expect = 4e-13
Identities = 71/249 (28%), Positives = 100/249 (40%), Gaps = 39/249 (15%)
Query: 1959 CCPGHYGSECQ-ACPGGPSSPCSDRGVCMDGMSGSGQCLCRSGFAGTACELCAPGAFGPH 2017
C PG+ G+ C SSPC + G C+D ++G QC C+ G +G CE+
Sbjct: 595 CNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGY-QCNCQPGTSGVNCEINFDDCASNP 653
Query: 2018 CQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEAVCRAG-NSC 2076
C +HG C +G+ SC C G+TG RC + ++ + PC A C G N
Sbjct: 654 C------IHGICMDGINRY-SCVCSPGFTGQRCNI--DIDECASNPCRKGATCINGVNGF 704
Query: 2077 ECSLGYEGDGRVCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWSCRA---- 2132
C + EG + + + C H NC+ G + CL D G +C
Sbjct: 705 RC-ICPEGPHHPSCYSQVNECLSNPCI-HGNCT--GGLSGYKCLCDAGWVGINCEVDKNE 760
Query: 2133 --RNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGDGLQCLEESEPPVDRCLGQPPP 2190
NPC +G G C +N RC C G+ G Q +D C P
Sbjct: 761 CLSNPCQNG--GTCDNL-------VNGYRCTCKKGFKGYNCQV------NIDECASN--P 803
Query: 2191 CHSDAMCTD 2199
C + C D
Sbjct: 804 CLNQGTCFD 812
Score = 76.3 bits (186), Expect = 4e-13
Identities = 94/387 (24%), Positives = 132/387 (34%), Gaps = 99/387 (25%)
Query: 41 HVPCTSCAAIKKQTCPSGWLRELPDQITQDCRYE-VQLGGSMVSM-SGCRRKCRKQVVQK 98
H CT + K C +GW+ + +C Q GG+ ++ +G R C+K
Sbjct: 731 HGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKK----- 785
Query: 99 ACCPGYWGSRCH----ECPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPN 154
G+ G C EC A PC GTC D + TC C + G CQ P
Sbjct: 786 ----GFKGYNCQVNIDEC---ASNPCLNQGTCFDDIS-GYTCHCVLPYTGKNCQTVLAPC 837
Query: 155 RFGPDCQSVCSCV-----------------------------------HGVCNHGPRGDG 179
P C++ C HG+C H +G
Sbjct: 838 SPNP-CENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLC-HNTQGSY 895
Query: 180 SCLCFAGYTGPHCDQELPVCQELRCPQNTQC--SAEAPSCRCLPGYTQQGSECRAP-NPC 236
C C G++G C++++ C C C SC CLPG+T G +C+ N C
Sbjct: 896 MCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFT--GDKCQTDMNEC 953
Query: 237 WPSPCSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPK-DPCTDN--------LGGCPSNS 287
PC CS C C + DG+ C + CT++ + G S S
Sbjct: 954 LSEPCKNGGTCS-DYVNSYTCKCQAGF--DGVHCENNINECTESSCFNGGTCVDGINSFS 1010
Query: 288 TLCVYQKPGQAFC----------------TCRPGLVSINSNASAG--------CFAFCSP 323
LC G +FC TC GL + + G CS
Sbjct: 1011 CLCPVGFTG-SFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSR 1069
Query: 324 FSCDRSATCQVTADGKTSCVCRESEVG 350
C TC V ++ C+C G
Sbjct: 1070 SPCKNKGTC-VQKKAESQCLCPSGWAG 1095
Score = 75.9 bits (185), Expect = 5e-13
Identities = 73/277 (26%), Positives = 100/277 (36%), Gaps = 40/277 (14%)
Query: 100 CCPGYWGSRC----HECPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNR 155
C G+ G C +EC PC GTC D + C C++ F+G CQ D
Sbjct: 745 CDAGWVGINCEVDKNEC---LSNPCQNGGTC-DNLVNGYRCTCKKGFKGYNCQVNIDECA 800
Query: 156 FGPDCQSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQELPVCQELRCPQNTQC----S 211
P C + +C + + +C C YTG +C L C C C +
Sbjct: 801 SNP-CLNQGTCFDDISGY------TCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPN 853
Query: 212 AEAPSCRCLPGYTQQGSECRAP-NPCWPSPCSLLAQCSVSPKGQAQCHCPENYHGDGMVC 270
E+ +C C PG+ QG C + C PC C + +G C CP + GM C
Sbjct: 854 FESYTCLCAPGW--QGQRCTIDIDECISKPCMNHGLCH-NTQGSYMCECPPGF--SGMDC 908
Query: 271 LPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPGL------VSINSNASAGC--FAFCS 322
++ D L N C+ C C PG +N S C CS
Sbjct: 909 --EEDIDDCLANPCQNGGSCM-DGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCS 965
Query: 323 PFSCDRSATCQVTADG----KTSCVCRESEVGDGRAC 355
+ + CQ DG C ES +G C
Sbjct: 966 DYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTC 1002
Score = 74.3 bits (181), Expect = 1e-12
Identities = 73/288 (25%), Positives = 99/288 (34%), Gaps = 60/288 (20%)
Query: 1954 TWKPSCCPGHYGSECQAC--PGGPSSPCSDRGVCMDGMSGSGQCLCRSGFAGTACE---- 2007
+++ C G G C + P PS PC + G C + +C C GF G+ CE
Sbjct: 204 SYQCQCPQGFTGQYCDSLYVPCAPS-PCVNGGTCRQTGDFTFECNCLPGFEGSTCERNID 262
Query: 2008 ----------------------LCAPGAFGPHC---------QACRCTVHGRCDEGLGGS 2036
C P G C Q C G C GG
Sbjct: 263 DCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGY 322
Query: 2037 GSCFCDEGWTGPRCEVQLELQPVCTPPCAPEAVC---RAGNSCECSLGYEGDGRVCTVAD 2093
G C C GW+G C ++ C P + C A SC C G G +C + D
Sbjct: 323 G-CVCVNGWSGDDCSENID--DCAFASCTPGSTCIDRVASFSCMCPEGKA--GLLCHLDD 377
Query: 2094 LCQDGHGGCSEHANC--SQVGTMVTCTCLPDYEGDGWSCRARNPCTDGHRGGCSEHANCL 2151
C C + A C + + CTC Y+G + + C + C C+
Sbjct: 378 ACIS--NPCHKGALCDTNPLNGQYICTCPQGYKGADCT-EDVDECAMANSNPCEHAGKCV 434
Query: 2152 STGLNTRRCECHAGYVGDGLQCLEESEPPVDRCLGQPPPCHSDAMCTD 2199
+T CEC GY G E ++ C PC +DA C D
Sbjct: 435 NTD-GAFHCECLKGYAG------PRCEMDINEC--HSDPCQNDATCLD 473
Score = 74.3 bits (181), Expect = 1e-12
Identities = 98/354 (27%), Positives = 123/354 (34%), Gaps = 82/354 (23%)
Query: 1271 KCVNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRGCSY--TCAKKIQ--VPDCCPGFFG 1326
KCVN F C L+ C S C TC KI C PGF G
Sbjct: 432 KCVNTDGAFHCEC---LKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKG 488
Query: 1327 TLCE----PCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEV------------- 1369
CE C C +GQC D+ + +C C GF G C++
Sbjct: 489 VHCELEINECQSN---PCVNNGQCVDK-VNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNG 544
Query: 1370 -------------CELGRYGPNCTGVCD------CAHGLCQEGLQGDGSCVCNVGWQGLR 1410
C G G C D C HG CQ+G+ +C+CN G+ G
Sbjct: 545 AKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSY-TCICNPGYMGAI 603
Query: 1411 CDQKITSPQC-PRKCDPNANCVQDSAGASTCACAAGYSGNGIFCS-EVDPCAHG---HGG 1465
C +I +C C + C+ D C C G S G+ C D CA HG
Sbjct: 604 CSDQI--DECYSSPCLNDGRCI-DLVNGYQCNCQPGTS--GVNCEINFDDCASNPCIHGI 658
Query: 1466 CSPHANCTKVAPGQRTCTCQDGYMGDGELCQ-EINSCLIHHGGCHIHAECIPTGPQQVSC 1524
C N + +C C G+ G+ C +I+ C C A CI G C
Sbjct: 659 CMDGIN-------RYSCVCSPGF--TGQRCNIDIDECA--SNPCRKGATCI-NGVNGFRC 706
Query: 1525 SCREG------YSGDGIRTCELLDPCSKNN--GGCSPYATCKSTGDGQRTCTCD 1570
C EG YS + C L +PC N GG S Y G C D
Sbjct: 707 ICPEGPHHPSCYS--QVNEC-LSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVD 757
Score = 73.9 bits (180), Expect = 2e-12
Identities = 88/349 (25%), Positives = 126/349 (36%), Gaps = 73/349 (20%)
Query: 1272 CVNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRGCSY-TCAKKIQVPDCC--PGFFGTL 1328
C+N FRC + SC + S C + C + C G+ G
Sbjct: 697 CINGVNGFRCICP---EGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGIN 753
Query: 1329 CEPCPGG-LGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEV------------------ 1369
CE L C G C D + C C +GF G C+V
Sbjct: 754 CEVDKNECLSNPCQNGGTC-DNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFD 812
Query: 1370 --------CELGRYGPNCTGV--------CDCAHGLCQEGLQGDG-SCVCNVGWQGLRCD 1412
C L G NC V C+ A +C+E + +C+C GWQG RC
Sbjct: 813 DISGYTCHCVLPYTGKNCQTVLAPCSPNPCENA-AVCKESPNFESYTCLCAPGWQGQRC- 870
Query: 1413 QKITSPQCPRKCDPNANCVQDSAGASTCACAAGYSGNGIFCSE------VDPCAHGHGGC 1466
I +C K N ++ G+ C C G+S G+ C E +PC +G G C
Sbjct: 871 -TIDIDECISKPCMNHGLCHNTQGSYMCECPPGFS--GMDCEEDIDDCLANPCQNG-GSC 926
Query: 1467 SPHANCTKVAPGQRTCTCQDGYMGDGELCQ-EINSCLIHHGGCHIHAECIPTGPQQVSCS 1525
N +C C G+ GD CQ ++N CL C C +C
Sbjct: 927 MDGVNTF-------SCLCLPGFTGD--KCQTDMNECLSE--PCKNGGTC-SDYVNSYTCK 974
Query: 1526 CREGYSGDGIRTCELLDPCSKNNGGCSPYATCKSTGDGQRTCTCDTAHT 1574
C+ G+ DG+ ++ C++++ C TC G +C C T
Sbjct: 975 CQAGF--DGVHCENNINECTESS--CFNGGTCVD-GINSFSCLCPVGFT 1018
Score = 70.1 bits (170), Expect = 3e-11
Identities = 81/326 (24%), Positives = 120/326 (36%), Gaps = 80/326 (24%)
Query: 716 MEQGCCKGFFGPDCTQCPGGFS-------------NPCYGKGNCSDGIQGNGACLCFPDY 762
+ +G C G CP G++ +PC KG C + CLC +
Sbjct: 1035 LNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQK-KAESQCLCPSGW 1093
Query: 763 KGIACHICSNPNKHGEQCQEDCG------CVH-GLCDNRPGSGGVCQQGTCAPGFSGRFC 815
G C + PN + G C H G+C N G+ CQ C G++G +C
Sbjct: 1094 AGAYCDV---PNVSCDIAASRRGVLVEHLCQHSGVCINA-GNTHYCQ---CPLGYTGSYC 1146
Query: 816 NESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEG----------------DGFSC 859
E + +C + C A C G RC C+ G++G +G +C
Sbjct: 1147 EEQLDECA----SNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTC 1202
Query: 860 TP---SNPCSHPD--RG--------GCSENAECVPGS-----LGTHHCTCHKGWSGDGRV 901
CS P RG C+ C+ G +G + C C G++G+ R
Sbjct: 1203 IDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGE-RC 1261
Query: 902 CVAIDECELDMRGGCHTDALCSYVG-PGQSRCTCKLGFAGDGYQC----SPIDPCRAGNG 956
I+EC + C ++ + C C+ F G + P PC NG
Sbjct: 1262 EGDINEC---LSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCL--NG 1316
Query: 957 GCHGLATCRAVGGGQRVCTCPPGFGG 982
G +A+ G +C CPPGF G
Sbjct: 1317 GTCAVASNMPDGF---ICRCPPGFSG 1339
Score = 69.7 bits (169), Expect = 3e-11
Identities = 82/280 (29%), Positives = 106/280 (37%), Gaps = 64/280 (22%)
Query: 1319 DCCPGFFGTLCE----PCPGGL---GGVC-----SGHGQCQDRFLGS------------- 1353
+C PGF G+ CE CP GGVC + + +C ++ G
Sbjct: 247 NCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQP 306
Query: 1354 ------GECHCHEGFHGTACEVCELGRYGPNCT-GVCDCAHGLCQEGLQ-----GDGSCV 1401
G C G +G VC G G +C+ + DCA C G SC+
Sbjct: 307 NACQNGGTCANRNGGYGC---VCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCM 363
Query: 1402 CNVGWQGLRC---DQKITSPQCPRKCDPNANCVQDSA-GASTCACAAGYSGNGIFCSE-V 1456
C G GL C D I++P C A C + G C C GY G C+E V
Sbjct: 364 CPEGKAGLLCHLDDACISNP-----CHKGALCDTNPLNGQYICTCPQGYKGAD--CTEDV 416
Query: 1457 DPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQ-EINSCLIHHGGCHIHAECI 1515
D CA + HA G C C GY G C+ +IN C H C A C+
Sbjct: 417 DECAMANSNPCEHAGKCVNTDGAFHCECLKGYA--GPRCEMDINEC--HSDPCQNDATCL 472
Query: 1516 PTGPQQVSCSCREGYSGD----GIRTCELLDPCSKNNGGC 1551
+C C G+ G I C+ +PC NNG C
Sbjct: 473 DK-IGGFTCLCMPGFKGVHCELEINECQ-SNPC-VNNGQC 509
Score = 69.3 bits (168), Expect = 5e-11
Identities = 67/256 (26%), Positives = 90/256 (35%), Gaps = 51/256 (19%)
Query: 100 CCPGYWGSRC----HECPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSAC----QECQ 151
C G+ G C +EC E+ C GTC+DG++ + +C+C F GS C EC
Sbjct: 975 CQAGFDGVHCENNINEC---TESSCFNGGTCVDGIN-SFSCLCPVGFTGSFCLHEINECS 1030
Query: 152 DPNRFGPDCQSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQELPVCQELRCPQNTQCS 211
C + +CV G+ G C C GYTG +C + +C C C
Sbjct: 1031 SH-----PCLNEGTCVDGL------GTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCV 1079
Query: 212 AEAPSCRCLPGYTQQGSECRAPNPCWPSPCSL-------LAQCS---VSPKGQAQCHCPE 261
+ +CL G+ C PN S L Q S ++ C CP
Sbjct: 1080 QKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPL 1139
Query: 262 NYHGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAF-----CTCRPGLVSINSNASAG 316
Y G C + L C SN C + F C C PG +N
Sbjct: 1140 GYTG--------SYCEEQLDECASNP--CQHGATCSDFIGGYRCECVPGYQGVNCEYEVD 1189
Query: 317 CFAFCSPFSCDRSATC 332
C C TC
Sbjct: 1190 ---ECQNQPCQNGGTC 1202
Score = 54.7 bits (130), Expect = 1e-06
Identities = 60/242 (24%), Positives = 79/242 (32%), Gaps = 30/242 (12%)
Query: 1959 CCPGHYGSECQACPGGP-SSPCSDRGV--CMDGMSGSGQCLCRSGFAGTACELCAPGAFG 2015
C PG G C+ S+PCS G C+ ++ C+CRS F G CE F
Sbjct: 1252 CLPGFAGERCEGDINECLSNPCSSEGSLDCIQ-LTNDYLCVCRSAFTGRHCE-----TFV 1305
Query: 2016 PHCQACRCTVHGRC--DEGLGGSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEAVCRAG 2073
C C G C + C C G++G RC+ + CR G
Sbjct: 1306 DVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQ-----------SSCGQVKCRKG 1354
Query: 2074 NSCECSLGYEGDGRVCTVADLCQDG--HGGCSEHANC--SQVGTMVTCTCLPDYEGDGWS 2129
C + G C C+ G C +C + +C C P + G
Sbjct: 1355 EQCVHTA--SGPRCFCPSPRDCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCE 1412
Query: 2130 CRARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGDGLQCLEESEPPVDRCLGQPP 2189
P T A+ G+ C HA DG C E P C P
Sbjct: 1413 LYTAPPSTPPATCLSQYCADKARDGVCDEACNSHA-CQWDGGDCSLTMENPWANC-SSPL 1470
Query: 2190 PC 2191
PC
Sbjct: 1471 PC 1472
Score = 53.5 bits (127), Expect = 3e-06
Identities = 76/320 (23%), Positives = 93/320 (29%), Gaps = 92/320 (28%)
Query: 1320 CCPGFFGTLCEP----CPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACE------- 1368
C PG G LCE C G C GQC DR +G C C GF G CE
Sbjct: 1213 CPPGTRGLLCEENIDDC--ARGPHCLNGGQCMDR-IGGYSCRCLPGFAGERCEGDINECL 1269
Query: 1369 ---------------------VCELGRYGPNCTGVCD-CAHGLCQEG--------LQGDG 1398
VC G +C D C C G +
Sbjct: 1270 SNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGF 1329
Query: 1399 SCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTCACAAGYSGNGIFCSEVDP 1458
C C G+ G RC KC CV ++G C C + S P
Sbjct: 1330 ICRCPPGFSGARCQSSCGQV----KCRKGEQCVHTASG-PRCFCPSPRDCESGCAS--SP 1382
Query: 1459 CAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINSCLIHHGGCHIHAECIPTG 1518
C HG G C P P +C C + G E
Sbjct: 1383 CQHG-GSCHPQRQ-----PPYYSCQCAPPFSGS-------------------RCELYTAP 1417
Query: 1519 PQQVSCSCREGYSGDGIR--TCELL---DPCSKNNGGCS-----PYATCKST------GD 1562
P +C Y D R C+ C + G CS P+A C S +
Sbjct: 1418 PSTPPATCLSQYCADKARDGVCDEACNSHACQWDGGDCSLTMENPWANCSSPLPCWDYIN 1477
Query: 1563 GQRTCTCDTAHTVGDGLTCR 1582
Q C+T + D C+
Sbjct: 1478 NQCDELCNTVECLFDNFECQ 1497
Score = 43.1 bits (100), Expect = 0.004
Identities = 31/122 (25%), Positives = 44/122 (36%), Gaps = 17/122 (13%)
Query: 1459 CAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINSCLIHHGGCHIHAECIPTG 1518
C G+ C C G C C +G++ GE CQ + C C C+
Sbjct: 28 CRDGYEPCVNEGMCVTYHNGTGYCKCPEGFL--GEYCQHRDPC--EKNRCQNGGTCVAQA 83
Query: 1519 P-QQVSCSCREGYSGDGIR-----TCELLDPCSKNNGGCSPYATCKSTGDGQRTCTCDTA 1572
+ +C C G++G+ + C + PC NGG TC CTC
Sbjct: 84 MLGKATCRCASGFTGEDCQYSTSHPCFVSRPCL--NGG-----TCHMLSRDTYECTCQVG 136
Query: 1573 HT 1574
T
Sbjct: 137 FT 138
Score = 42.0 bits (97), Expect = 0.008
Identities = 44/170 (25%), Positives = 58/170 (34%), Gaps = 29/170 (17%)
Query: 666 CVDCQALNTSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKGCASYCNQTIMEQG--CCKG 723
C LN TC S D F C P G + + C S C Q +G C
Sbjct: 1308 CPQMPCLNGGTCAVASNMPDGFICRC-----PPGFSGAR--CQSSCGQVKCRKGEQCVHT 1360
Query: 724 FFGPDCTQCP-------GGFSNPCYGKGNCSDGIQGNG-ACLCFPDYKGIACHICSNPNK 775
GP C CP G S+PC G+C Q +C C P + G C + + P
Sbjct: 1361 ASGPRCF-CPSPRDCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAP-- 1417
Query: 776 HGEQCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPT 825
C+ C ++ + G C + C GDC T
Sbjct: 1418 ---PSTPPATCLSQYCADK------ARDGVCDEACNSHACQWDGGDCSLT 1458
Score = 40.0 bits (92), Expect = 0.030
Identities = 43/185 (23%), Positives = 55/185 (29%), Gaps = 50/185 (27%)
Query: 100 CCPGYWGSRCHE----CPGGAETPCNGHGTCL--DGMDRNGTCVCQENFRGSACQE---- 149
C + G C CP + PC GTC M C C F G+ CQ
Sbjct: 1292 CRSAFTGRHCETFVDVCP---QMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQ 1348
Query: 150 ------------CQDPNRFGP---DCQSVCS---CVHGVCNHGPRGDG--SCLCFAGYTG 189
P F P DC+S C+ C HG H R SC C ++G
Sbjct: 1349 VKCRKGEQCVHTASGPRCFCPSPRDCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSG 1408
Query: 190 PHCDQELP-------VCQELRCPQNTQCSAEAPSCR----------CLPGYTQQGSECRA 232
C+ C C + +C C + C +
Sbjct: 1409 SRCELYTAPPSTPPATCLSQYCADKARDGVCDEACNSHACQWDGGDCSLTMENPWANCSS 1468
Query: 233 PNPCW 237
P PCW
Sbjct: 1469 PLPCW 1473
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 105 bits (262), Expect = 6e-22
Identities = 118/379 (31%), Positives = 134/379 (35%), Gaps = 85/379 (22%)
Query: 1892 EPPCPEGSQEQGSPEACWRFYPKFWTSPPLHS-------LGLRSVWVHPSLWGRPQGLGR 1944
E CPEG G E C P + +G R V P+ W P R
Sbjct: 770 EADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTR 829
Query: 1945 GCHRN---CVTTTWKPSCCPGHYGSECQ-ACPGGPSSP-CSDRGVCMDGMSG----SGQC 1995
N C T SC PG G CQ AC G P CS C G SG C
Sbjct: 830 CSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLC 889
Query: 1996 LCRSGFAGTACE-LCAPGAFGPHC-QACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCE-- 2051
LC +G+ G CE C G FGP C Q C+C CD SG+C C GW G CE
Sbjct: 890 LCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDH---VSGACTCPAGWRGTFCEHA 946
Query: 2052 -----VQLELQPVCTPPCAPEAVCRAGN-SCECSLGYEGD-----------GRVCTVADL 2094
L+ + C C A C A N SC C G G G C+ A
Sbjct: 947 CPAGFFGLDCRSACN--CTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACA 1004
Query: 2095 CQDG------HGGCSEHANCSQVGTMVTCTCLPDYEGDG--WSCRARNPCT----DGH-- 2140
C +G HG C H +G C GD SC +N T GH
Sbjct: 1005 CFNGASCDPVHGQC--HCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCA 1062
Query: 2141 -------------------RGGCSEHANCLSTGL---NTRRCECHAGYVGDGLQ--CLEE 2176
R GC CL+ GL +T RC C AG+ GD Q CL
Sbjct: 1063 CPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRG 1122
Query: 2177 --SEPPVDRCLGQP-PPCH 2192
E RC P CH
Sbjct: 1123 WFGEACAQRCSCPPGAACH 1141
Score = 105 bits (261), Expect = 8e-22
Identities = 94/326 (28%), Positives = 125/326 (38%), Gaps = 55/326 (16%)
Query: 1272 CVNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKKIQVPDCCP--------- 1322
C + T RC GF ++C SF C+ C + P C P
Sbjct: 1140 CHHVTGACRCPPGFTGSGC-EQAC---PPGSFGEDCAQMCQCPGENPACHPATGTCSCAA 1195
Query: 1323 GFFGTLCEP-CPGGLGGV-------CSGHGQCQDRFLGSGECHCHEGFHGTACEV-CELG 1373
G+ G C+ CP G G C G C +G C C GF GT C + C G
Sbjct: 1196 GYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCD---AATGACRCPTGFLGTDCNLTCPQG 1252
Query: 1374 RYGPNCTGVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQD 1433
R+GPNCT VC C G + + G+C+C G G+RC++ + C+ +C
Sbjct: 1253 RFGPNCTHVCGCGQGAACDPV--TGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNG 1310
Query: 1434 S---AGASTCACAAGYSGN--GIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGY 1488
A +C+C G++G + C A H CS H N T P TC C G+
Sbjct: 1311 GLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNST-CEPATGTCRCGPGF 1369
Query: 1489 MGDGELCQEINSCLIHHGGCHIHAEC---IPTGPQQVSCSCREGYSGDGIRTCELLDPCS 1545
G+ C+ H GC C P P C C G+ G CE
Sbjct: 1370 Y--GQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHG---HFCE------ 1418
Query: 1546 KNNGGCSPYATCKSTGDG-QRTCTCD 1570
GC P S G+G + C CD
Sbjct: 1419 ---RGCEP----GSFGEGCHQRCDCD 1437
Score = 101 bits (251), Expect = 1e-20
Identities = 94/342 (27%), Positives = 121/342 (35%), Gaps = 79/342 (23%)
Query: 1273 VNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKKIQVPDC---CPGFFGTLC 1329
++C CT G D SC+ +G R C+ TC +C C F G C
Sbjct: 954 LDCRSACNCTAGAAC-DAVNGSCLCPAGRRGPR-CAETCPAHTYGHNCSQACACFNGASC 1011
Query: 1330 EPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTAC-EVCELGRYGPNCTGVCDCAHG 1388
+P HGQC HC G+ G +C + C G YG NC C
Sbjct: 1012 DPV----------HGQC----------HCAPGWMGPSCLQACPAGLYGDNCRHSC----- 1046
Query: 1389 LCQEGLQGD---GSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQD---SAGASTCAC 1442
LCQ G D G C C GW GL C+++ C + C+ C C
Sbjct: 1047 LCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLC 1106
Query: 1443 AAGYSGNGIFCSEVDPCAHGHGG--------CSPHANCTKVAPGQRTCTCQDGYMGD--- 1491
AG++G+ C PC G G C P A C V C C G+ G
Sbjct: 1107 PAGWTGDK--CQ--SPCLRGWFGEACAQRCSCPPGAACHHVT---GACRCPPGFTGSGCE 1159
Query: 1492 --------GELCQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLDP 1543
GE C ++ C + CH P +CSC GY G +C+ P
Sbjct: 1160 QACPPGSFGEDCAQMCQCPGENPACH---------PATGTCSCAAGYHGP---SCQQRCP 1207
Query: 1544 CSKNNGGCSPYATCKSTGD---GQRTCTCDTAHTVGD-GLTC 1581
+ GC C + G C C T D LTC
Sbjct: 1208 PGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTC 1249
Score = 100 bits (250), Expect = 1e-20
Identities = 102/368 (27%), Positives = 134/368 (36%), Gaps = 49/368 (13%)
Query: 16 CLAGFSFVRGQVLFKGCDVKTTFVTHVPCTSCAAIKKQTCP--SGWLRELPDQITQDCRY 73
C AGF +G+ + C V T V C+S + C +G R P + +DC
Sbjct: 718 CPAGF---QGEDCGQECPVGTFGVN---CSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEA 771
Query: 74 EVQLG----GSMVSMSGCRR--KCRKQVVQKACCPGYWGSRCHE-CPGGAETP-CNGHGT 125
+ G G C+ +C + C PG+ GSRC + CP G P C +
Sbjct: 772 DCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCS 831
Query: 126 CL-DGM--DRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCV--HGVCNHGPRGDGS 180
C DG G C C + G +CQ D +GPDC C+C HG C+ G
Sbjct: 832 CANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCD---AISGL 888
Query: 181 CLCFAGYTGPHCDQELPV------C-QELRCPQNTQCSAEAPSCRCLPGYTQQGSECRAP 233
CLC AGY GP C+Q+ P C Q +C C + +C C G+ E P
Sbjct: 889 CLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACP 948
Query: 234 NPCWPSPCSLLAQCSVSPKGQA---QCHCPENYHGDGMVCLPKDPCTDNLGGCPS----- 285
+ C C+ A C CP G C P C
Sbjct: 949 AGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPR--CAETCPAHTYGHNCSQACACF 1006
Query: 286 NSTLCVYQKPGQAFCTCRPGLVSINSNASAGCFAFCSPFSCDRSATCQ--VTADGKTS-C 342
N C P C C PG + + C A +C S CQ T D + C
Sbjct: 1007 NGASC---DPVHGQCHCAPGW--MGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHC 1061
Query: 343 VCRESEVG 350
C E G
Sbjct: 1062 ACPEGWAG 1069
Score = 97.8 bits (242), Expect = 1e-19
Identities = 91/320 (28%), Positives = 115/320 (35%), Gaps = 47/320 (14%)
Query: 1280 RCTQGFQLQDTPRKSCVYRSGFSFSRGCS---YTCAKKIQVPDCCPGFFGTLCE-PCPGG 1335
RC GFQ +D ++ V G + S CS C C PG G CE CP G
Sbjct: 717 RCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEG 776
Query: 1336 LGGV--------CSGHGQCQDRFLGSGECHCHEGFHGTAC-EVCELGRYGPNCTGVCDCA 1386
G+ C +C +G C C GF G+ C +VC G YGP+C C CA
Sbjct: 777 RWGLGCQEICPACQHAARCDPE---TGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCA 833
Query: 1387 H-GLCQEGLQGDGSCVCNVGWQGLRCDQKITS----PQCPRKCDPNANCVQDSAGASTCA 1441
+ G C G C C GW G C + + P C C+ +A A + C
Sbjct: 834 NDGHCH---PATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCL 890
Query: 1442 CAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQR---TCTCQDGYMGDGELCQEI 1498
C AGY G C + P H GC C A CTC G+ G C+
Sbjct: 891 CEAGYVGPR--CEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWR--GTFCE-- 944
Query: 1499 NSCLIHHGGCHIHAECIPTGPQQV-----SCSCREGYSGDGIRTCELLDPCSKNNGGCSP 1553
++C G + C T SC C G G C P CS
Sbjct: 945 HACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGP---RCAETCPAHTYGHNCSQ 1001
Query: 1554 YATCKSTGDGQRTCTCDTAH 1573
C + +CD H
Sbjct: 1002 ACACFN------GASCDPVH 1015
Score = 97.4 bits (241), Expect = 2e-19
Identities = 100/342 (29%), Positives = 121/342 (35%), Gaps = 69/342 (20%)
Query: 676 TCPPNSVKLDIFPKECVYIHDPTGLNVLKK-----GCASYCNQTIMEQGCCKGFFGPDCT 730
TCPP D F K C + C + T E GC KG++G C
Sbjct: 554 TCPP-----DTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCR 608
Query: 731 QCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQCQEDCGCVH-- 788
+ C +G C + GACLC P G CH+ P G C E+C CV
Sbjct: 609 K-----KCNCANRGRCH---RLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPH 660
Query: 789 -GLCDNRPGSGGVCQQGTCAPGFSGRFCNE--SMGDCGP-TGLAQHCHLHARCVSQEGVA 844
CD R GS C +C GF G C +G GP A C + C S G
Sbjct: 661 TQSCDKRDGS---C---SCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGEC 714
Query: 845 RCRCLDGFEGD-----------GFSCTPSNPCSHPDRGGCSENAECVPGSLGTH-HCTCH 892
RC GF+G+ G +C+ S C G + C PG G C
Sbjct: 715 GKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCP 774
Query: 893 KGWSGDG--RVCVAIDECELDMRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDP 950
+G G G +C A C A C P C C GF G Q D
Sbjct: 775 EGRWGLGCQEICPA-----------CQHAARCD---PETGACLCLPGFVGSRCQ----DV 816
Query: 951 CRAGNGGCHGLATCRAVGGGQ-----RVCTCPPGFGGDGFSC 987
C AG G C G C+C PG+ GFSC
Sbjct: 817 CPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGW--TGFSC 856
Score = 95.9 bits (237), Expect = 5e-19
Identities = 77/242 (31%), Positives = 99/242 (40%), Gaps = 48/242 (19%)
Query: 1320 CCPGFFGTLCEPC--PGGLGGVCS-------GHGQCQDRFLGSGECHCHEGFHGTACEV- 1369
C PG+ G C+ G G CS GHG C SG C C G+ G CE
Sbjct: 847 CAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAI---SGLCLCEAGYVGPRCEQQ 903
Query: 1370 CELGRYGPNCTGVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSP----QCPRKCD 1425
C G +GP C C C HG + + G+C C GW+G C+ + C C+
Sbjct: 904 CPQGHFGPGCEQRCQCQHGAACDHV--SGACTCPAGWRGTFCEHACPAGFFGLDCRSACN 961
Query: 1426 PNANCVQDSAGASTCACAAGYSGNGIFCSEVDPCAHGHG-GCSPHANCTKVA---PGQRT 1481
A D+ S C C AG G C+E P AH +G CS C A P
Sbjct: 962 CTAGAACDAVNGS-CLCPAGRRGPR--CAETCP-AHTYGHNCSQACACFNGASCDPVHGQ 1017
Query: 1482 CTCQDGYMGD-----------GELCQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGY 1530
C C G+MG G+ C+ +SCL +GG C P C+C EG+
Sbjct: 1018 CHCAPGWMGPSCLQACPAGLYGDNCR--HSCLCQNGG-----TCDPVSGH---CACPEGW 1067
Query: 1531 SG 1532
+G
Sbjct: 1068 AG 1069
Score = 95.5 bits (236), Expect = 6e-19
Identities = 94/329 (28%), Positives = 117/329 (35%), Gaps = 89/329 (27%)
Query: 717 EQGCCKGFFGPDCTQCPGGFSNPCY---GKGNCSDGIQGNGACLCFPDYKGIACHICSNP 773
++ C G +GPDC S+PC G G+C D I +G CLC Y G C
Sbjct: 857 QRACDTGHWGPDC-------SHPCNCSAGHGSC-DAI--SGLCLCEAGYVGPRCEQQCPQ 906
Query: 774 NKHGEQCQEDCGCVHGL-CDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGL----A 828
G C++ C C HG CD+ G C TC G+ G FC + G GL A
Sbjct: 907 GHFGPGCEQRCQCQHGAACDH---VSGAC---TCPAGWRGTFCEHAC-PAGFFGLDCRSA 959
Query: 829 QHCHLHARCVSQEGVARC-------RCLDGFEGDGFSCTPSNPCSHPDRGGCSE---NAE 878
+C A C + G C RC + + S C+ + C
Sbjct: 960 CNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCH 1019
Query: 879 CVPGSLG-------------------------------THHCTCHKGWSGDGRVCVAIDE 907
C PG +G + HC C +GW+G E
Sbjct: 1020 CAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAG----LACEKE 1075
Query: 908 C-ELDMRGGCHTDALCSYVG---PGQSRCTCKLGFAGDGYQCSPIDPCRAGNGG------ 957
C D+R GC C G P RC C G+ GD Q PC G G
Sbjct: 1076 CLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQ----SPCLRGWFGEACAQR 1131
Query: 958 --CHGLATCRAVGGGQRVCTCPPGFGGDG 984
C A C V G C CPPGF G G
Sbjct: 1132 CSCPPGAACHHVTGA---CRCPPGFTGSG 1157
Score = 95.1 bits (235), Expect = 8e-19
Identities = 89/318 (27%), Positives = 114/318 (35%), Gaps = 76/318 (23%)
Query: 55 CPSGWLREL------PDQITQDCRYEV--QLGGSMVSMSG-------------------- 86
CP GW + PD ++C + Q GG+ S++G
Sbjct: 542 CPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSGTNCEDGCPKG 601
Query: 87 -----CRRKC------RKQVVQKACC--PGYWGSRCH-ECPGGAETP-CNGHGTCLDGMD 131
CR+KC R + AC PG +G CH CP A P C+ C+
Sbjct: 602 YYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHT 661
Query: 132 -----RNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHGVCNHGPRGDGSCLCFAG 186
R+G+C C+ FRG CQ + FGP C C+C GV G+ C AG
Sbjct: 662 QSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAG 721
Query: 187 YTGPHCDQELPV------CQELRCPQNTQCSAEAPSCRCLPGYTQQGSECRAPNPCWPSP 240
+ G C QE PV C C CRC PG T + E P W
Sbjct: 722 FQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLG 781
Query: 241 CSLLAQCSVSPKGQAQCHC-PENYHGDGMVCLP-------KDPCTDNLGGCPSNSTLCV- 291
C + P Q C PE +CLP +D C G PS T C
Sbjct: 782 CQ-----EICPACQHAARCDPET---GACLCLPGFVGSRCQDVCPAGWYG-PSCQTRCSC 832
Query: 292 ----YQKPGQAFCTCRPG 305
+ P C+C PG
Sbjct: 833 ANDGHCHPATGHCSCAPG 850
Score = 95.1 bits (235), Expect = 8e-19
Identities = 78/262 (29%), Positives = 97/262 (37%), Gaps = 37/262 (14%)
Query: 1320 CCPGFFGTLCE-PCPG-GLGGVCSGHGQCQDRFLGS-----GECHCHEGFHGTACEV-CE 1371
C PG +G C CP G CS QC S G C C GF G C+ CE
Sbjct: 628 CDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECE 687
Query: 1372 LGRYGPNCTGVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCV 1431
LG +GP C C C G+ + + G+ C G+QG C Q+ C + +C
Sbjct: 688 LGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCG 747
Query: 1432 QDSAGAST--CACAAGYSGN-----------GIFCSEVDPCAHGHGGCSPHANCTKVAPG 1478
T C C G +G G+ C E+ P C P PG
Sbjct: 748 GAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPG 807
Query: 1479 QRTCTCQD----GYMGDGELCQEINSCLIHHGGCHI---HAECIPTGPQQVSC--SCREG 1529
CQD G+ G CQ SC + G CH H C P G SC +C G
Sbjct: 808 FVGSRCQDVCPAGWYGPS--CQTRCSC-ANDGHCHPATGHCSCAP-GWTGFSCQRACDTG 863
Query: 1530 YSGDGIRTCELLDPCSKNNGGC 1551
+ G C CS +G C
Sbjct: 864 HWGP---DCSHPCNCSAGHGSC 882
Score = 94.7 bits (234), Expect = 1e-18
Identities = 90/300 (30%), Positives = 111/300 (37%), Gaps = 78/300 (26%)
Query: 717 EQGCCKGFFGPDCTQ---CPGGFSNP-CYGKGNCSDGIQGNGACLCFPDYKGIACHICSN 772
EQ C G FG DC Q CPG NP C+ G C C Y G +C
Sbjct: 1159 EQACPPGSFGEDCAQMCQCPG--ENPACH---------PATGTCSCAAGYHGPSCQQRCP 1207
Query: 773 PNKHGEQCQEDCGCVH-GLCDNRPGSGGVCQQGTCAPGFSGRFCNES--MGDCGPT---- 825
P ++G C++ CGC++ G CD + G C+ C GF G CN + G GP
Sbjct: 1208 PGRYGPGCEQLCGCLNGGSCD---AATGACR---CPTGFLGTDCNLTCPQGRFGPNCTHV 1261
Query: 826 ---GLAQHCH-LHARCVSQEGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVP 881
G C + C+ G A RC G + F GC C
Sbjct: 1262 CGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGV------------GCEHTCSCRN 1309
Query: 882 GSL---GTHHCTCHKGWSG--------DGRVCVAIDECELDMRGGCHTDALCSYVGPGQS 930
G L C+C GW+G GR A C L+ CH ++ C P
Sbjct: 1310 GGLCHASNGSCSCGLGWTGRHCELACPPGRYGAA---CHLEC--SCHNNSTCE---PATG 1361
Query: 931 RCTCKLGFAGDGYQCSPIDPCRAG--NGGCHGL------ATCRAVGGGQRVCTCPPGFGG 982
C C GF G + PC G GC GL A C + G C CP GF G
Sbjct: 1362 TCRCGPGFYGQACE----HPCPPGFHGAGCQGLCWCQHGAPCDPISGR---CLCPAGFHG 1414
Score = 92.8 bits (229), Expect = 4e-18
Identities = 93/332 (28%), Positives = 123/332 (37%), Gaps = 72/332 (21%)
Query: 1289 DTPRKSCVYRSGFSFSRGCSY--TCAKKIQVPDCCPGFFGTLCEP-CPGGLGGV------ 1339
DT K+C SFS C TC C PG GT CE CP G G
Sbjct: 558 DTFGKNC------SFSCSCQNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKC 611
Query: 1340 -CSGHGQCQDRFLGSGECHCHEGFHGTACEV-CELGRYGPNCTGVCDCAHGLCQEGLQGD 1397
C+ G+C + G C C G +G C + C +GP C+ C C Q + D
Sbjct: 612 NCANRGRCHRLY---GACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRD 668
Query: 1398 GSCVCNVGWQGLRCDQKIT----SPQCPRKCDPNANCVQDS-AGASTCACAAGYSGN--- 1449
GSC C G++G RC + P C + C DS +G C AG+ G
Sbjct: 669 GSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCG 728
Query: 1450 --------GIFCSEVDPCAHGHGGCSPHANCTKVAPGQR----TCTCQDGYMGDGELCQE 1497
G+ CS C+ G C + PG+ C +G G G CQE
Sbjct: 729 QECPVGTFGVNCS--SSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLG--CQE 784
Query: 1498 INSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIR----------TCELLDPCSKN 1547
I H C P+ +C C G+ G + +C+ C+ N
Sbjct: 785 ICPACQHAARC---------DPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCA-N 834
Query: 1548 NGGCSP---YATCKSTGDG---QRTCTCDTAH 1573
+G C P + +C G QR CDT H
Sbjct: 835 DGHCHPATGHCSCAPGWTGFSCQR--ACDTGH 864
Score = 92.8 bits (229), Expect = 4e-18
Identities = 91/318 (28%), Positives = 116/318 (36%), Gaps = 77/318 (24%)
Query: 707 CASYCNQTIMEQGCCKGFFGPDCTQCPGGFSNPCYGKGNCSDGI---QGNGACLCFPDYK 763
C + T E C GFFG DC + C NC+ G NG+CLC +
Sbjct: 934 CPAGWRGTFCEHACPAGFFGLDC-------RSAC----NCTAGAACDAVNGSCLCPAGRR 982
Query: 764 GIACHICSNPNKHGEQCQEDCGCVHGL-CDNRPGSGGVCQQGTCAPGFSGRFCNESMGDC 822
G C + +G C + C C +G CD G Q CAPG+ G C ++
Sbjct: 983 GPRCAETCPAHTYGHNCSQACACFNGASCDPVHG------QCHCAPGWMGPSCLQAC--- 1033
Query: 823 GPTGLAQHCHLHARCVSQEG------VARCRCLDGFEGDGFSCTPSNPCSHPD-RGGCSE 875
P GL H+ C+ Q G C C +G+ G +C C D R GC
Sbjct: 1034 -PAGLYGDNCRHS-CLCQNGGTCDPVSGHCACPEGWA--GLAC--EKECLPRDVRAGCRH 1087
Query: 876 NAECVPGSLGTHH---CTCHKGWSGD-----------GRVCVAIDECELDMRGGCHTDAL 921
+ C+ G L H C C GW+GD G C R C A
Sbjct: 1088 SGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACA--------QRCSCPPGAA 1139
Query: 922 CSYVGPGQSRCTCKLGFAGDGYQ-----------CSPIDPCRAGNGGCH---GLATCRA- 966
C +V C C GF G G + C+ + C N CH G +C A
Sbjct: 1140 CHHV---TGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAG 1196
Query: 967 VGGGQRVCTCPPGFGGDG 984
G CPPG G G
Sbjct: 1197 YHGPSCQQRCPPGRYGPG 1214
Score = 91.7 bits (226), Expect = 9e-18
Identities = 78/227 (34%), Positives = 95/227 (41%), Gaps = 35/227 (15%)
Query: 786 CVHG-LCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGP-TGLAQHCHLHARCVSQEGV 843
C HG C PGS C C PGF G C + +C G QH RCV+ G
Sbjct: 133 CFHGGRCV--PGSAQPCH---CPPGFQGPRCQYDVDECRTHNGGCQH-----RCVNTPGS 182
Query: 844 ARCRCLDGF--EGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGW--SGDG 899
C C GF D +C N C+ GGC + CV ++ H C C G+ DG
Sbjct: 183 YLCECKPGFRLHTDSRTCLAINSCA-LGNGGCQHH--CVQLTITRHRCQCRPGFQLQEDG 239
Query: 900 RVCVAIDECELDMRGGCHTDALCSYVGPGQSRCTCKLGF--AGDGYQCSPIDPCRAGNGG 957
R CV C + G C C V G +RC C +G+ A DG C +D C AG
Sbjct: 240 RHCVRRSPC-ANRNGSCM--HRCQVV-RGLARCECHVGYQLAADGKACEDVDECAAGLAQ 295
Query: 958 C-HGLATCRAVGGGQRVCTCPPGF--GGDGFSCYG---DIFRELEAN 998
C HG + G C C G+ G DG CY +I EAN
Sbjct: 296 CAHGCLNTQ----GSFKCVCHAGYELGADGRQCYRIEMEIVNSCEAN 338
Score = 90.5 bits (223), Expect = 2e-17
Identities = 83/282 (29%), Positives = 105/282 (37%), Gaps = 52/282 (18%)
Query: 97 QKACCPGYWGSRCHECPGGAETPCN---GHGTCLDGMDRNGTCVCQENFRGSACQECQDP 153
Q+AC G+WG C PCN GHG+C D + +G C+C+ + G C++
Sbjct: 857 QRACDTGHWGPDCSH-------PCNCSAGHGSC-DAI--SGLCLCEAGYVGPRCEQQCPQ 906
Query: 154 NRFGPDCQSVCSCVHG-VCNHGPRGDGSCLCFAGYTGPHCDQELPV------CQE-LRCP 205
FGP C+ C C HG C+H G+C C AG+ G C+ P C+ C
Sbjct: 907 GHFGPGCEQRCQCQHGAACDH---VSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCT 963
Query: 206 QNTQCSAEAPSCRCLPGYTQQGSEC--RAPNPCWPSPCSLLAQC----SVSPKGQAQCHC 259
C A SC C G ++G C P + CS C S P QCHC
Sbjct: 964 AGAACDAVNGSCLCPAG--RRGPRCAETCPAHTYGHNCSQACACFNGASCDPV-HGQCHC 1020
Query: 260 PENYHGDGMVCLPKDPCTDNLGGCPSNSTLCVYQ---KPGQAFCTCRPGLVSINSNASAG 316
+ G CL P C +S LC P C C G A
Sbjct: 1021 APGWMGPS--CLQACPAGLYGDNC-RHSCLCQNGGTCDPVSGHCACPEGW------AGLA 1071
Query: 317 CFAFCSP----FSCDRSATC--QVTADGKTS-CVCRESEVGD 351
C C P C S C D T C+C GD
Sbjct: 1072 CEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGD 1113
Score = 87.0 bits (214), Expect = 2e-16
Identities = 108/404 (26%), Positives = 142/404 (35%), Gaps = 115/404 (28%)
Query: 1933 PSLWGRPQGLGRGCHRN--CVTTTWKPSCCPGHYGSECQ-ACPGG-------PSSPCSDR 1982
P +G+ C C + T C PG G+ C+ CP G C++R
Sbjct: 557 PDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANR 616
Query: 1983 GVCMDGMSGSGQCLCRSGFAGTACEL-CAPGAFGPHC-QACRCTV-HGR-CDEGLGGSGS 2038
G C G CLC G G C L C P AFGP C + C+C H + CD+ GS
Sbjct: 617 GRCHRLY---GACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKR---DGS 670
Query: 2039 CFCDEGWTGPRCEVQLELQPVCTPPCAPEAVCRAGNSCE---------CSLGYEGD--GR 2087
C C G+ G RC+ + EL P C C G +C+ C G++G+ G+
Sbjct: 671 CSCKAGFRGERCQAECEL-GYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQ 729
Query: 2088 VCTVADL------------------------------------CQDGHGG---------C 2102
C V C +G G C
Sbjct: 730 ECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPAC 789
Query: 2103 SEHANCS-QVGTMVTCTCLPDYEGD--------GW---SCRARNPC-TDGHRGGCSEHAN 2149
A C + G C CLP + G GW SC+ R C DGH + H +
Sbjct: 790 QHAARCDPETG---ACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCS 846
Query: 2150 CLS--TGLNTRR--------------CECHAGYVG----DGLQCLEESEPPVDRCLGQPP 2189
C TG + +R C C AG+ GL CL E+ RC Q P
Sbjct: 847 CAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGL-CLCEAGYVGPRCEQQCP 905
Query: 2190 PCHSDAMCTDLHFQEKRAGVFHLQ-ATSGPYGLNFSEAEAACEA 2232
H C + A H+ A + P G + E AC A
Sbjct: 906 QGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPA 949
Score = 87.0 bits (214), Expect = 2e-16
Identities = 84/319 (26%), Positives = 112/319 (35%), Gaps = 56/319 (17%)
Query: 53 QTCPSGWLRELPDQITQDCRYEV--QLGGSMVSMSGCRRKCRKQVVQKACCPGYWGSRCH 110
Q CP+G + +CR+ Q GG+ +SG AC G+ G C
Sbjct: 1031 QACPAGLYGD-------NCRHSCLCQNGGTCDPVSG----------HCACPEGWAGLACE 1073
Query: 111 -EC-PGGAETPCNGHGTCLDGM---DRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCS 165
EC P C G CL+G G C+C + G CQ FG C CS
Sbjct: 1074 KECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCS 1133
Query: 166 CVHGVCNHGPRGDGSCLCFAGYTGPHCDQELP-------VCQELRCP-QNTQCSAEAPSC 217
C G H G+C C G+TG C+Q P Q +CP +N C +C
Sbjct: 1134 CPPGAACH--HVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTC 1191
Query: 218 RCLPGYTQQGSECRAPNPCWPSPCSLLAQC---SVSPKGQAQCHCPENYHG-DGMVCLPK 273
C GY + R P + C L C C CP + G D + P+
Sbjct: 1192 SCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQ 1251
Query: 274 ---DPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPGLVSI-------NSNASAGCFAFCSP 323
P ++ GC + P C C PG + + GC C
Sbjct: 1252 GRFGPNCTHVCGCGQGAAC----DPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTC-- 1305
Query: 324 FSCDRSATCQVTADGKTSC 342
SC C ++G SC
Sbjct: 1306 -SCRNGGLCH-ASNGSCSC 1322
Score = 85.9 bits (211), Expect = 5e-16
Identities = 64/200 (32%), Positives = 82/200 (41%), Gaps = 21/200 (10%)
Query: 2012 GAFGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEAVCR 2071
G C A C GRC G + C C G+ GPRC+ ++ C V
Sbjct: 122 GCLSAECSASLCFHGGRCVPG--SAQPCHCPPGFQGPRCQYDVDECRTHNGGCQHRCVNT 179
Query: 2072 AGN-SCECSLGY--EGDGRVCTVADLCQDGHGGCSEHANCSQVG-TMVTCTCLPDY--EG 2125
G+ CEC G+ D R C + C G+GGC H C Q+ T C C P + +
Sbjct: 180 PGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHH--CVQLTITRHRCQCRPGFQLQE 237
Query: 2126 DGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGY--VGDGLQCLEESEPPVDR 2183
DG C R+PC +R G H + GL RCECH GY DG C + VD
Sbjct: 238 DGRHCVRRSPC--ANRNGSCMHRCQVVRGL--ARCECHVGYQLAADGKACED-----VDE 288
Query: 2184 CLGQPPPCHSDAMCTDLHFQ 2203
C C + T F+
Sbjct: 289 CAAGLAQCAHGCLNTQGSFK 308
Score = 84.0 bits (206), Expect = 2e-15
Identities = 85/274 (31%), Positives = 111/274 (40%), Gaps = 62/274 (22%)
Query: 1253 LTVGSSRCLHSHAEAL-----REKCVNCT---RRFRCTQGFQLQDTPRKSCVYRSGFSFS 1304
L S CL ++ AL + CV T R +C GFQLQ+ R CV RS +
Sbjct: 193 LHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRH-CVRRSPCANR 251
Query: 1305 RG-CSYTC--AKKIQVPDCCPGFF----GTLCEP---CPGGLGGVCSGHGQCQDRFLGSG 1354
G C + C + + +C G+ G CE C GL G Q GS
Sbjct: 252 NGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQ----GSF 307
Query: 1355 ECHCHEGFHGTACEVCELGRYGPNCTGV-------CDCAHGLCQEGLQGDGS---CVCNV 1404
+C CH G+ ELG G C + C+ +G C G + C C
Sbjct: 308 KCVCHAGY--------ELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPR 359
Query: 1405 GWQGLRCDQKIT--------SPQCPRKCDPNANCVQDSAGASTCACAAGY--SGNGIFCS 1454
G++ L DQ+ SP C + C N G C C AGY S +G C
Sbjct: 360 GYE-LDTDQRTCIDVDDCADSPCCQQVCTNNP-------GGYECGCYAGYRLSADGCGCE 411
Query: 1455 EVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGY 1488
+VD CA GGC H CT +A G C+C+ GY
Sbjct: 412 DVDECASSRGGCEHH--CTNLA-GSFQCSCEAGY 442
Score = 83.2 bits (204), Expect = 3e-15
Identities = 84/292 (28%), Positives = 109/292 (37%), Gaps = 63/292 (21%)
Query: 720 CCKGFFGPDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQ 779
C FG DC+ + C G C G+ G C C + G+ C+ P+ G+
Sbjct: 511 CLDDSFGHDCSLT----CDDCRNGGTCLLGLDG---CDCPEGWTGLICNETCPPDTFGKN 563
Query: 780 CQEDCGCVH-GLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCV 838
C C C + G CD+ G+ C+ C PG SG C + C +HC C
Sbjct: 564 CSFSCSCQNGGTCDSVTGA---CR---CPPGVSGTNCEDG---CPKGYYGKHCRKKCNCA 614
Query: 839 SQEGVAR----CRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGT-----HHC 889
++ R C C G G T P GCSE +CV + C
Sbjct: 615 NRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGP---GCSEECQCVQPHTQSCDKRDGSC 671
Query: 890 TCHKGWSGDGRVCVAIDECELDMRG-GCHTDALCSYVG------PGQSRCTCKLGFAGD- 941
+C G+ G+ C A ECEL G GC C VG G+ C GF G+
Sbjct: 672 SCKAGFRGER--CQA--ECELGYFGPGCWQACTCP-VGVACDSVSGECGKRCPAGFQGED 726
Query: 942 ----------GYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGFGGD 983
G CS C G CHG+ GQ C CPPG G+
Sbjct: 727 CGQECPVGTFGVNCS--SSCSCGGAPCHGVT-------GQ--CRCPPGRTGE 767
Score = 83.2 bits (204), Expect = 3e-15
Identities = 97/382 (25%), Positives = 117/382 (30%), Gaps = 119/382 (31%)
Query: 677 CPPNSVKLDIF-----PKECVYIHDPTGLNVLKKGCASYCNQTIMEQGCCKGFFGPDCTQ 731
CPP S D P E H TG CA+ + +Q C G +GP C Q
Sbjct: 1162 CPPGSFGEDCAQMCQCPGENPACHPATGTC----SCAAGYHGPSCQQRCPPGRYGPGCEQ 1217
Query: 732 CPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQCQEDCGC----- 786
G C G+C GAC C + G C++ + G C CGC
Sbjct: 1218 LCG-----CLNGGSCD---AATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAA 1269
Query: 787 ---VHGLCDNRPGSGGV-CQQG-----------------------------TCAPGFSGR 813
V G C PG GV C++G +C G++GR
Sbjct: 1270 CDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGR 1329
Query: 814 FCNESMGDCGPTGLAQHCHLHARC----VSQEGVARCRCLDGFEGDGFSCTPSNPCSHPD 869
C + C P CHL C + CRC GF G C HP
Sbjct: 1330 HCELA---CPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQA--------CEHPC 1378
Query: 870 RGG-----------CSENAEC--------VPGSLGTHHCT--CHKGWSGDGRVCVAIDEC 908
G C A C P H C C G G+G C
Sbjct: 1379 PPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEG----CHQRC 1434
Query: 909 ELDMRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGG--------CHG 960
+ D C PG+S TC L CR G G C G
Sbjct: 1435 DCDGGAPCDPVTGLCLCPPGRSGATCNL-------------DCRRGQFGPSCTLHCDCGG 1481
Query: 961 LATCRAVGGGQRVCTCPPGFGG 982
A C V G C C G+ G
Sbjct: 1482 GADCDPVSG---QCHCVDGYMG 1500
Score = 82.4 bits (202), Expect = 5e-15
Identities = 108/391 (27%), Positives = 136/391 (34%), Gaps = 94/391 (24%)
Query: 1959 CCPGHYGSEC-QACPGGP-SSPCSDRGVCMDGMSGS---GQCLCRSGFAGTAC-ELCAPG 2012
C G G C + CP CS C +G S GQC C G+ G +C + C G
Sbjct: 977 CPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAG 1036
Query: 2013 AFGPHCQ-ACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEAVCR 2071
+G +C+ +C C G CD SG C C EGW G CE + + V C C
Sbjct: 1037 LYGDNCRHSCLCQNGGTCDPV---SGHCACPEGWAGLACEKECLPRDV-RAGCRHSGGCL 1092
Query: 2072 AGNSCE-------CSLGYEGD-----------GRVCTVADLCQDGHGGCSEHANCSQVGT 2113
G C+ C G+ GD G C A C C A C V
Sbjct: 1093 NGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEAC--AQRC-----SCPPGAACHHV-- 1143
Query: 2114 MVTCTCLPDYEGDGWSCRARNPCTDGHRG-GCSEHANCLSTGLN------TRRCECHAGY 2166
C C P + G G C G G C++ C G N T C C AGY
Sbjct: 1144 TGACRCPPGFTGSG----CEQACPPGSFGEDCAQMCQC--PGENPACHPATGTCSCAAGY 1197
Query: 2167 VGDGLQCLEESEPPVDRCLGQPPPCHSDAMCTDLHFQEKRAGVFHLQATSGPYGLNFSEA 2226
G Q RC PP C E+ G + G + A
Sbjct: 1198 HGPSCQ---------QRC----PPGRYGPGC------EQLCGCLN--------GGSCDAA 1230
Query: 2227 EAACEAQGAVLASFPQLSAAQ-QLG---FHLCLMGWLANGSTAHPVVFPVADCGNGRVGI 2282
AC L + L+ Q + G H+C G G+ PV C GR G+
Sbjct: 1231 TGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCG---QGAACDPVT-GTCLCPPGRAGV 1286
Query: 2283 -VSLGARKNLSERWDAYCFRVQDVACRCRNG 2312
G +N R+ C + C CRNG
Sbjct: 1287 RCERGCPQN---RFGVGC----EHTCSCRNG 1310
Score = 82.4 bits (202), Expect = 5e-15
Identities = 73/251 (29%), Positives = 98/251 (39%), Gaps = 41/251 (16%)
Query: 1274 NCTRRFRCTQGFQLQDTPRKSCVYRSGFS------------FSRGCSYTCAKKIQ----- 1316
NCT C QG D +C+ G + F GC +TC+ +
Sbjct: 1257 NCTHVCGCGQGAAC-DPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHA 1315
Query: 1317 ---VPDCCPGFFGTLCEPC--PGGLGGVCSGHGQCQDRFL---GSGECHCHEGFHGTACE 1368
C G+ G CE PG G C C + +G C C GF+G ACE
Sbjct: 1316 SNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACE 1375
Query: 1369 -VCELGRYGPNCTGVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQ----CPRK 1423
C G +G C G+C C HG + + G C+C G+ G C++ C ++
Sbjct: 1376 HPCPPGFHGAGCQGLCWCQHGAPCDPISG--RCLCPAGFHGHFCERGCEPGSFGEGCHQR 1433
Query: 1424 CDPNANCVQDSAGASTCACAAGYSGN--GIFC--SEVDPCAHGHGGCSPHANCTKVAPGQ 1479
CD + D C C G SG + C + P H C A+C V+ GQ
Sbjct: 1434 CDCDGGAPCDPV-TGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVS-GQ 1491
Query: 1480 RTCTCQDGYMG 1490
C C DGYMG
Sbjct: 1492 --CHCVDGYMG 1500
Score = 81.3 bits (199), Expect = 1e-14
Identities = 99/382 (25%), Positives = 143/382 (37%), Gaps = 73/382 (19%)
Query: 1281 CTQGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKK--IQVPDCCPGFF----GTLC---EP 1331
C GFQ PR + + GC + C + +C PGF C
Sbjct: 149 CPPGFQ---GPRCQYDVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINS 205
Query: 1332 CPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCTGVCDCAH--GL 1389
C G GG C H C + C C GF +L G +C CA+ G
Sbjct: 206 CALGNGG-CQHH--CVQLTITRHRCQCRPGF--------QLQEDGRHCVRRSPCANRNGS 254
Query: 1390 CQEGLQ---GDGSCVCNVGWQGLRCDQKITSP--QCPRKCDPNANCVQDSAGASTCACAA 1444
C Q G C C+VG+Q L D K +C A+ ++ G+ C C A
Sbjct: 255 CMHRCQVVRGLARCECHVGYQ-LAADGKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHA 313
Query: 1445 GYS--GNGIFCSEVD-----PCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGE--LC 1495
GY +G C ++ C +GGCS + T P CTC GY D + C
Sbjct: 314 GYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGP---LCTCPRGYELDTDQRTC 370
Query: 1496 QEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGY--SGDGIRTCELLDPCSKNNGGCSP 1553
+++ C + P C C GY S DG CE +D C+ + GGC
Sbjct: 371 IDVDDC----ADSPCCQQVCTNNPGGYECGCYAGYRLSADGCG-CEDVDECASSRGGCEH 425
Query: 1554 YATCKSTGDGQRTCTCDTAHTVGDGLTCRARVGLELLRDKHASFFSLRLLEYKELKGDGP 1613
+ T + G C+C+ + + + R G L + +L G+ P
Sbjct: 426 HCTNLA---GSFQCSCEAGYRLHED-----RRGCSPLEEPMV-----------DLDGELP 466
Query: 1614 FTIFVPHADLMSNLSQDELARI 1635
F +PH ++ QDEL ++
Sbjct: 467 FVRPLPHIAVL----QDELPQL 484
Score = 80.9 bits (198), Expect = 2e-14
Identities = 66/210 (31%), Positives = 86/210 (40%), Gaps = 35/210 (16%)
Query: 99 ACCPGYWGSRCHECPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGP 158
AC PG +G+ CH E C+ + TC GTC C F G AC+ P G
Sbjct: 1334 ACPPGRYGAACH-----LECSCHNNSTCEPA---TGTCRCGPGFYGQACEHPCPPGFHGA 1385
Query: 159 DCQSVCSCVHGV-CNHGPRGDGSCLCFAGYTGPHCDQEL-PVCQELRCPQNTQCSAEAPS 216
CQ +C C HG C+ G CLC AG+ G C++ P C Q C AP
Sbjct: 1386 GCQGLCWCQHGAPCDPI---SGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPC 1442
Query: 217 ------CRCLPGYTQQGSECRAP---NPCWPSPCSLLAQCSVSPKGQ---AQCHCPENYH 264
C C PG + G+ C PS C+L C QCHC + Y
Sbjct: 1443 DPVTGLCLCPPG--RSGATCNLDCRRGQFGPS-CTLHCDCGGGADCDPVSGQCHCVDGYM 1499
Query: 265 G-----DGMVCLPKDP--CTDNLGGCPSNS 287
G G + LP++P + G P++S
Sbjct: 1500 GPTCREGGPLRLPENPSLAQGSAGTLPASS 1529
Score = 79.7 bits (195), Expect = 3e-14
Identities = 95/376 (25%), Positives = 123/376 (32%), Gaps = 118/376 (31%)
Query: 48 AAIKKQTCPSGWLRELPDQITQDCRYEVQLGGSMVSMSGCRRKCRKQVVQKACCPGYWGS 107
A ++ +CP G +T CR GS GC ++AC PG +G
Sbjct: 1127 ACAQRCSCPPG---AACHHVTGACRCPPGFTGS-----GC---------EQACPPGSFGE 1169
Query: 108 RCHE---CPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVC 164
C + CPG E P T GTC C + G +CQ+ P R+GP C+ +C
Sbjct: 1170 DCAQMCQCPG--ENPACHPAT--------GTCSCAAGYHGPSCQQRCPPGRYGPGCEQLC 1219
Query: 165 SCVHG-----------------------VCNHGPRG------------------DGSCLC 183
C++G C G G G+CLC
Sbjct: 1220 GCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLC 1279
Query: 184 FAGYTGPHCDQELPV------CQE-LRCPQNTQCSAEAPSCRCLPGYTQQGSECRAPNPC 236
G G C++ P C+ C C A SC C G+T + E P
Sbjct: 1280 PPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPPGR 1339
Query: 237 WPSPCSL---------------LAQCSVSPKGQAQCH-CPENYHGDGMV----CLPKDPC 276
+ + C L +C GQA H CP +HG G C PC
Sbjct: 1340 YGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPC 1399
Query: 277 TDNLGGCPSNSTLCVYQKPGQAFCT--CRPGLVSINSNASAGCFAFCSPFSCDRSATCQV 334
G C LC G FC C PG + GC C CD A C
Sbjct: 1400 DPISGRC-----LCPAGFHGH-FCERGCEPG------SFGEGCHQRC---DCDGGAPCDP 1444
Query: 335 TADGKTSCVCRESEVG 350
C+C G
Sbjct: 1445 VTG---LCLCPPGRSG 1457
Score = 79.3 bits (194), Expect = 4e-14
Identities = 93/351 (26%), Positives = 121/351 (34%), Gaps = 108/351 (30%)
Query: 720 CCKGFFG-PDCTQCPGG--FSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHI-CSNPNK 775
CC+G+ PD C ++ C+ G C G C C P ++G C
Sbjct: 110 CCRGWMQQPDEEGCLSAECSASLCFHGGRCVPG--SAQPCHCPPGFQGPRCQYDVDECRT 167
Query: 776 HGEQCQEDCGCVHG--LCDNRPG-------------------SGGV---CQQGT------ 805
H CQ C G LC+ +PG +GG C Q T
Sbjct: 168 HNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRC 227
Query: 806 -CAPGFS----GRFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFE--GDGFS 858
C PGF GR C G H RC G+ARC C G++ DG +
Sbjct: 228 QCRPGFQLQEDGRHCVRRSPCANRNGSCMH-----RCQVVRGLARCECHVGYQLAADGKA 282
Query: 859 CTPSNPCSHPDRGGCSENAECVPGSL---GTHHCTCHKGWS--GDGRVCVAID-----EC 908
C + C+ + A+C G L G+ C CH G+ DGR C I+ C
Sbjct: 283 CEDVDECA-------AGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSC 335
Query: 909 ELDMRGGC-----HTDA-----------------------------LCSYV---GPGQSR 931
E + GGC HT A C V PG
Sbjct: 336 EAN-NGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYE 394
Query: 932 CTCKLGF--AGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGF 980
C C G+ + DG C +D C + GGC T A G C+C G+
Sbjct: 395 CGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLA---GSFQCSCEAGY 442
Score = 79.0 bits (193), Expect = 6e-14
Identities = 93/346 (26%), Positives = 116/346 (33%), Gaps = 80/346 (23%)
Query: 1890 GLEPPCPEGSQEQGSPEACWRFYPKFWTSPPLHSLGLRSVWVHPSLWGR--PQGLGRGCH 1947
G E CP GS + + C P + + + PS R P G GC
Sbjct: 1157 GCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCE 1216
Query: 1948 R--------NCVTTTWKPSCCPGHYGSECQ-ACPGGPSSP-CSDRGVCMDGMSG---SGQ 1994
+ +C T C G G++C CP G P C+ C G + +G
Sbjct: 1217 QLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGT 1276
Query: 1995 CLCRSGFAGTACEL-CAPGAFGPHCQ-ACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEV 2052
CLC G AG CE C FG C+ C C G C +GSC C GWTG CE+
Sbjct: 1277 CLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCH---ASNGSCSCGLGWTGRHCEL 1333
Query: 2053 QLELQPVCTPPCAPEAVCRAGNSCECSLGYEGDGRVCTVADLCQDGHGGCSEHANCSQVG 2112
C P R G +C H CS H N +
Sbjct: 1334 ------ACPPG-------RYGAAC----------------------HLECSCHNNSTCEP 1358
Query: 2113 TMVTCTCLPDYEGDGWSCRARNPCTDGHRGG-------CSEHANC--------LSTGLNT 2157
TC C P + G +PC G G C A C G +
Sbjct: 1359 ATGTCRCGPGFYGQA----CEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHG 1414
Query: 2158 RRCE--CHAGYVGDGL--QCLEESEPPVDRCLG--QPPPCHSDAMC 2197
CE C G G+G +C + P D G PP S A C
Sbjct: 1415 HFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATC 1460
Score = 78.2 bits (191), Expect = 1e-13
Identities = 81/287 (28%), Positives = 109/287 (37%), Gaps = 51/287 (17%)
Query: 1320 CCPGFF------GTLCEPCPGGLGGVCSGHGQCQDRFLGSGE-CHCHEGFHGTACEVCEL 1372
CC G+ G L C L C G+C GS + CHC GF G C+
Sbjct: 110 CCRGWMQQPDEEGCLSAECSASL---CFHGGRCVP---GSAQPCHCPPGFQGPRCQYD-- 161
Query: 1373 GRYGPNCTGVCDCAHGLCQE---GLQGDGSCVCNVGWQGLRCDQK--ITSPQCPR-KCDP 1426
C +G CQ G C C G++ L D + + C
Sbjct: 162 -------VDECRTHNGGCQHRCVNTPGSYLCECKPGFR-LHTDSRTCLAINSCALGNGGC 213
Query: 1427 NANCVQDSAGASTCACAAGYS--GNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTC 1484
+CVQ + C C G+ +G C PCA+ +G C +V G C C
Sbjct: 214 QHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRC---QVVRGLARCEC 270
Query: 1485 QDGYM--GDGELCQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGYS--GDGIRTC-- 1538
GY DG+ C++++ C C H C+ T C C GY DG R C
Sbjct: 271 HVGYQLAADGKACEDVDECAAGLAQC-AHG-CLNT-QGSFKCVCHAGYELGADG-RQCYR 326
Query: 1539 ---ELLDPCSKNNGGCSPYATCKSTGDGQRTCTCDTAHTVG-DGLTC 1581
E+++ C NNGGCS + S G CTC + + D TC
Sbjct: 327 IEMEIVNSCEANNGGCSHGCSHTSAGP---LCTCPRGYELDTDQRTC 370
Score = 73.6 bits (179), Expect = 2e-12
Identities = 72/238 (30%), Positives = 90/238 (37%), Gaps = 55/238 (23%)
Query: 711 CNQTIMEQGCCKGFFGPDCTQC--PGGFSNPCYGKGNCSDGIQ---GNGACLCFPDYKGI 765
C+ + C G+ G C PG + C+ + +C + G C C P + G
Sbjct: 1313 CHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQ 1372
Query: 766 ACHICSNPNKHGEQCQEDCGCVHGL-CDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGP 824
AC P HG CQ C C HG CD P SG + C GF G FC C P
Sbjct: 1373 ACEHPCPPGFHGAGCQGLCWCQHGAPCD--PISG----RCLCPAGFHGHFCERG---CEP 1423
Query: 825 TGLAQHCHLHARCVSQEGVARCRCLDGFEGDGFSCTP-SNPC-SHPDRGGCSENAECVPG 882
+ CH RC C DG G C P + C P R G + N +C G
Sbjct: 1424 GSFGEGCH-----------QRCDC-DG----GAPCDPVTGLCLCPPGRSGATCNLDCRRG 1467
Query: 883 SLG---THHCTCHKGWSGDGRVCVAIDECELDMRGGCHTDALCSYVGPGQSRCTCKLG 937
G T HC C G G C + G CH + Y+GP TC+ G
Sbjct: 1468 QFGPSCTLHCDC-----GGGADCDPVS-------GQCH--CVDGYMGP-----TCREG 1506
Score = 71.6 bits (174), Expect = 9e-12
Identities = 69/246 (28%), Positives = 96/246 (39%), Gaps = 42/246 (17%)
Query: 1952 TTTWKPSCCPGHYGSECQACPGGPSSPCSDRGVCMDGMSGSGQCLCRSGFAGTAC-ELCA 2010
T T K C +G +C C + G C+ G+ G C C G+ G C E C
Sbjct: 504 TLTEKFVCLDDSFGHDCSLT----CDDCRNGGTCLLGLDG---CDCPEGWTGLICNETCP 556
Query: 2011 PGAFGPHCQ-ACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCE-------VQLELQPVCTP 2062
P FG +C +C C G CD +G+C C G +G CE + C
Sbjct: 557 PDTFGKNCSFSCSCQNGGTCD---SVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCN- 612
Query: 2063 PCAPEAVC-RAGNSCECSLGYEGDGRVCTVADLCQDGHGGCSEHANCSQVGTMV------ 2115
CA C R +C C G GR C + GCSE C Q T
Sbjct: 613 -CANRGRCHRLYGACLCDPGLY--GRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDG 669
Query: 2116 TCTCLPDYEGDGWSCRARNPCTDGHRG-GCSEHANC---LSTGLNTRRC--ECHAGYVGD 2169
+C+C + G+ R + C G+ G GC + C ++ + C C AG+ G+
Sbjct: 670 SCSCKAGFRGE----RCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGE 725
Query: 2170 --GLQC 2173
G +C
Sbjct: 726 DCGQEC 731
Score = 70.1 bits (170), Expect = 3e-11
Identities = 78/309 (25%), Positives = 104/309 (33%), Gaps = 84/309 (27%)
Query: 110 HECPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHG 169
H+C + C GTCL G+D C C E + G C E P+ FG +C CSC +G
Sbjct: 518 HDCSLTCDD-CRNGGTCLLGLDG---CDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNG 573
Query: 170 ------------------------------------VCNHGPRGD-----GSCLCFAGYT 188
CN RG G+CLC G
Sbjct: 574 GTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLY 633
Query: 189 GPHCDQELP-------VCQELRC--PQNTQCSAEAPSCRCLPGYTQQGSECRAP------ 233
G C P +E +C P C SC C G+ +G C+A
Sbjct: 634 GRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGF--RGERCQAECELGYF 691
Query: 234 -NPCWPS-PCSLLAQCSVSPKGQAQCHCPENYHGD--GMVCLPKDPCTDNLGGCPSNSTL 289
CW + C + C S G+ CP + G+ G C + C
Sbjct: 692 GPGCWQACTCPVGVACD-SVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAP 750
Query: 290 CVYQKPGQAFCTCRPGLVSINSNASA-------GCFAFCSPFSCDRSATCQVTADGKT-S 341
C + GQ C C PG + A GC C +C +A C D +T +
Sbjct: 751 C-HGVTGQ--CRCPPGRTGEDCEADCPEGRWGLGCQEICP--ACQHAARC----DPETGA 801
Query: 342 CVCRESEVG 350
C+C VG
Sbjct: 802 CLCLPGFVG 810
Score = 65.9 bits (159), Expect = 5e-10
Identities = 70/267 (26%), Positives = 100/267 (37%), Gaps = 52/267 (19%)
Query: 70 DCRYEVQLGGSMVSMSGCRRKCRKQVVQK---ACCPGYW----GSRCHECPGGAETPCNG 122
D R + + + GC+ C + + + C PG+ G C +PC
Sbjct: 196 DSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVR-----RSPC-- 248
Query: 123 HGTCLDGMDRNGTCV--CQENFRGSACQECQDPNRFGPD---CQSVCSCVHGV--CNHG- 174
+RNG+C+ CQ RG A EC + D C+ V C G+ C HG
Sbjct: 249 -------ANRNGSCMHRCQV-VRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGC 300
Query: 175 --PRGDGSCLCFAGYT----GPHCDQ-ELPVCQELR-----CPQNTQCSAEAPSCRCLPG 222
+G C+C AGY G C + E+ + C ++ P C C G
Sbjct: 301 LNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRG 360
Query: 223 YTQQGSE--CRAPNPCWPSPCSLLAQCSVSPKGQAQCHCPENYH--GDGMVCLPKDPCTD 278
Y + C + C SPC C+ +P G +C C Y DG C D C
Sbjct: 361 YELDTDQRTCIDVDDCADSPCCQQV-CTNNPGGY-ECGCYAGYRLSADGCGCEDVDECAS 418
Query: 279 NLGGCPSNSTLCVYQKPGQAFCTCRPG 305
+ GGC + T G C+C G
Sbjct: 419 SRGGCEHHCT----NLAGSFQCSCEAG 441
Score = 65.1 bits (157), Expect = 9e-10
Identities = 68/257 (26%), Positives = 90/257 (35%), Gaps = 30/257 (11%)
Query: 1340 CSGHGQCQDRFLGSGECHCHEGFHGTAC-EVCELGRYGPNCTGVCDCAHGLCQEGLQGDG 1398
C G C LG C C EG+ G C E C +G NC+ C C +G + + G
Sbjct: 527 CRNGGTC---LLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSV--TG 581
Query: 1399 SCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAG---ASTCACAAGYSGNGIFCSE 1455
+C C G G C+ + C NC C C G G FC
Sbjct: 582 ACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGR--FCHL 639
Query: 1456 VDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMG-----DGELCQEINSCLIHHGGCHI 1510
P GCS C V P ++C +DG GE CQ C + + G
Sbjct: 640 TCPPWAFGPGCSEECQC--VQPHTQSCDKRDGSCSCKAGFRGERCQA--ECELGYFGPGC 695
Query: 1511 HAECIPTGPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKSTG-DGQRTCTC 1569
C T P V+C + SG+ + C P C + G + +C+C
Sbjct: 696 WQAC--TCPVGVAC---DSVSGECGKRC----PAGFQGEDCGQECPVGTFGVNCSSSCSC 746
Query: 1570 DTAHTVGDGLTCRARVG 1586
A G CR G
Sbjct: 747 GGAPCHGVTGQCRCPPG 763
Score = 64.3 bits (155), Expect = 1e-09
Identities = 63/207 (30%), Positives = 74/207 (35%), Gaps = 53/207 (25%)
Query: 1862 QLLEPPG-LGARCDHFETRPLRLNTCSI------CG-------LEPPCPEGSQEQGSPEA 1907
+L PPG GA C H E +TC CG E PCP G G
Sbjct: 1332 ELACPPGRYGAAC-HLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGL 1390
Query: 1908 CWRFYPKFWTSPPLHSLGLRSVWVHPSLWGRPQGL-GRGCHRNCVTTTWKPSCCPGHYGS 1966
CW + P + R + P G G C R C PG +G
Sbjct: 1391 CWCQH-----GAPCDPISGRCLC--------PAGFHGHFCERGCE---------PGSFGE 1428
Query: 1967 EC-QACPGGPSSPCSDRGVCMDGMSGSGQCLCRSGFAGTACEL-CAPGAFGPHCQA-CRC 2023
C Q C +PC +G CLC G +G C L C G FGP C C C
Sbjct: 1429 GCHQRCDCDGGAPCDPV---------TGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDC 1479
Query: 2024 TVHGRCDEGLGGSGSCFCDEGWTGPRC 2050
CD SG C C +G+ GP C
Sbjct: 1480 GGGADCDPV---SGQCHCVDGYMGPTC 1503
Score = 62.4 bits (150), Expect = 6e-09
Identities = 58/205 (28%), Positives = 74/205 (36%), Gaps = 29/205 (14%)
Query: 1369 VCELGRYGPNCTGVCD-CAHG-LCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDP 1426
VC +G +C+ CD C +G C GL G C C GW GL C++ + C
Sbjct: 510 VCLDDSFGHDCSLTCDDCRNGGTCLLGLDG---CDCPEGWTGLICNETCPPDTFGKNCSF 566
Query: 1427 NANCVQDSAGAS---TCACAAGYSGNGIFCSEVDPCAHGHGG--CSPHANCTKVAPGQR- 1480
+ +C S C C G SG C D C G+ G C NC R
Sbjct: 567 SCSCQNGGTCDSVTGACRCPPGVSGTN--CE--DGCPKGYYGKHCRKKCNCANRGRCHRL 622
Query: 1481 --TCTCQDGYMGDGELCQEINSCLIHHGGCHIHAECIPTGPQQV-----SCSCREGYSGD 1533
C C G G C GC +C+ Q SCSC+ G+ G+
Sbjct: 623 YGACLCDPGLY--GRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGE 680
Query: 1534 GIRT-CELLDPCSKNNGGCSPYATC 1557
+ CEL GC TC
Sbjct: 681 RCQAECEL----GYFGPGCWQACTC 701
Score = 60.8 bits (146), Expect = 2e-08
Identities = 85/309 (27%), Positives = 106/309 (34%), Gaps = 74/309 (23%)
Query: 1945 GCHRNCVTTTWKPSCCPGHYGSECQACPG----GPSSPCSDRGVCMDGMSGSG------- 1993
GC CV T PG Y EC+ PG S C C G G
Sbjct: 171 GCQHRCVNT-------PGSYLCECK--PGFRLHTDSRTCLAINSCALGNGGCQHHCVQLT 221
Query: 1994 ----QCLCRSGFA----GTACELCAPGAFGPHCQACRCTVHGRCDEGLGGSGSCFCDEGW 2045
+C CR GF G C +P A RC V + G C C G+
Sbjct: 222 ITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQV-------VRGLARCECHVGY 274
Query: 2046 T----GPRCEVQLELQPVCTPPCAPEAVCRAGN-SCECSLGYE--GDGRVC-----TVAD 2093
G CE ++ CA + G+ C C GYE DGR C + +
Sbjct: 275 QLAADGKACE-DVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVN 333
Query: 2094 LCQDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWSCRARNPCTDGHRGGCSEHANCLST 2153
C+ +GGCS CS CTC YE D + C D C++ C
Sbjct: 334 SCEANNGGCSH--GCSHTSAGPLCTCPRGYELD----TDQRTCID--VDDCADSPCCQQV 385
Query: 2154 GLNT---RRCECHAGY--VGDGLQCLEESEPPVDRCLGQPPPCHSDAMCTDLHFQEKRAG 2208
N C C+AGY DG C + VD C C + CT+L AG
Sbjct: 386 CTNNPGGYECGCYAGYRLSADGCGCED-----VDECASSRGGC--EHHCTNL------AG 432
Query: 2209 VFHLQATSG 2217
F +G
Sbjct: 433 SFQCSCEAG 441
Score = 58.5 bits (140), Expect = 8e-08
Identities = 51/178 (28%), Positives = 61/178 (34%), Gaps = 60/178 (33%)
Query: 1310 TCAKKIQVPDCCPGFFGTLCE-PCPGGLGGV-CSG-----HGQCQDRFLGSGECHCHEGF 1362
TC C PGF+G CE PCP G G C G HG D SG C C GF
Sbjct: 1355 TCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPI--SGRCLCPAGF 1412
Query: 1363 HGTACEV--------------------------------------------CELGRYGPN 1378
HG CE C G++GP+
Sbjct: 1413 HGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGPS 1472
Query: 1379 CTGVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAG 1436
CT CDC G + + G C C G+ G C + P + N + Q SAG
Sbjct: 1473 CTLHCDCGGGADCDPV--SGQCHCVDGYMGPTCRE-----GGPLRLPENPSLAQGSAG 1523
Score = 57.4 bits (137), Expect = 2e-07
Identities = 68/268 (25%), Positives = 106/268 (39%), Gaps = 48/268 (17%)
Query: 706 GCASYCNQTIMEQGCCKGFFGPDCTQCPGGFS-----NPCYGKGNCSDGIQGNGACL--C 758
GC +C Q + + C QC GF C + C++ NG+C+ C
Sbjct: 212 GCQHHCVQLTITRHRC---------QCRPGFQLQEDGRHCVRRSPCANR---NGSCMHRC 259
Query: 759 FPDYKGIA---CHICSNPNKHGEQCQE--DCG-----CVHGLCDNRPGSGGVCQQGTCAP 808
+G+A CH+ G+ C++ +C C HG + + VC G
Sbjct: 260 -QVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGY-EL 317
Query: 809 GFSGRFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGDGFSCTPSNPCSHP 868
G GR C + + A + C C C G+E D T C
Sbjct: 318 GADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELD----TDQRTCIDV 373
Query: 869 DRGGCSENAEC---VPGSLGTHHCTCHKGW--SGDGRVCVAIDECELDMRGGCHTDALCS 923
D C+++ C + G + C C+ G+ S DG C +DEC RGGC + C+
Sbjct: 374 D--DCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDEC-ASSRGGC--EHHCT 428
Query: 924 YVGPGQSRCTCKLGFA--GDGYQCSPID 949
+ G +C+C+ G+ D CSP++
Sbjct: 429 NLA-GSFQCSCEAGYRLHEDRRGCSPLE 455
Score = 57.4 bits (137), Expect = 2e-07
Identities = 44/141 (31%), Positives = 57/141 (40%), Gaps = 24/141 (17%)
Query: 97 QKACCPGYWGSRCHE---CPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDP 153
++ C PG +G CH+ C GGA PC+ G C+C G+ C
Sbjct: 1418 ERGCEPGSFGEGCHQRCDCDGGA--PCD---------PVTGLCLCPPGRSGATCNLDCRR 1466
Query: 154 NRFGPDCQSVCSCVHGV-CNHGPRGDGSCLCFAGYTGPHCDQELPVCQELRCPQNTQCSA 212
+FGP C C C G C+ G C C GY GP C + P LR P+N S
Sbjct: 1467 GQFGPSCTLHCDCGGGADCDPV---SGQCHCVDGYMGPTCREGGP----LRLPENP--SL 1517
Query: 213 EAPSCRCLPGYTQQGSECRAP 233
S LP ++ S P
Sbjct: 1518 AQGSAGTLPASSRPTSRSGGP 1538
Score = 56.6 bits (135), Expect = 3e-07
Identities = 54/218 (24%), Positives = 75/218 (34%), Gaps = 20/218 (9%)
Query: 151 QDPNRFGPDCQSVCSCVHGVCNHG----PRGDGSCLCFAGYTGPHCDQELPVCQELR--C 204
Q P+ G C S C +C HG P C C G+ GP C ++ C+ C
Sbjct: 116 QQPDEEG--CLSA-ECSASLCFHGGRCVPGSAQPCHCPPGFQGPRCQYDVDECRTHNGGC 172
Query: 205 PQNTQCSAEAPSCRCLPGYT--QQGSECRAPNPCWPSPCSLLAQCSVSPKGQAQCHCPEN 262
+ + C C PG+ C A N C C + +C C
Sbjct: 173 QHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPG 232
Query: 263 Y--HGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPGLVSINSNASAGCFAF 320
+ DG C+ + PC + G C + G A C C G +
Sbjct: 233 FQLQEDGRHCVRRSPCANRNGSCMHRCQVV----RGLARCECHVGYQLAADGKACEDVDE 288
Query: 321 CSPFSCDRSATCQVTADGKTSCVCRES-EVG-DGRACY 356
C+ + C + G CVC E+G DGR CY
Sbjct: 289 CAAGLAQCAHGC-LNTQGSFKCVCHAGYELGADGRQCY 325
Score = 53.9 bits (128), Expect = 2e-06
Identities = 57/209 (27%), Positives = 68/209 (32%), Gaps = 50/209 (23%)
Query: 2008 LCAPGAFGPHCQAC--RCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPVCTPP-- 2063
+C +FG C C G C GL G C C EGWTG C C P
Sbjct: 510 VCLDDSFGHDCSLTCDDCRNGGTCLLGLDG---CDCPEGWTGLIC------NETCPPDTF 560
Query: 2064 ---CAPEAVCRAGNSCE-------CSLGYEGDGRVCTVADLCQDGHGG--CSEHANCSQV 2111
C+ C+ G +C+ C G G D C G+ G C + NC+
Sbjct: 561 GKNCSFSCSCQNGGTCDSVTGACRCPPGVSG----TNCEDGCPKGYYGKHCRKKCNCANR 616
Query: 2112 G----TMVTCTCLPDYEGD-----------GWSCRARNPCTDGHRGGCSEHANCLS--TG 2154
G C C P G G C C H C + S G
Sbjct: 617 GRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAG 676
Query: 2155 LNTRRC--ECHAGYVGDGLQCLEESEPPV 2181
RC EC GY G G C + PV
Sbjct: 677 FRGERCQAECELGYFGPG--CWQACTCPV 703
>gi|56237021 fibrillin 3 precursor [Homo sapiens]
Length = 2809
Score = 105 bits (261), Expect = 8e-22
Identities = 89/362 (24%), Positives = 141/362 (38%), Gaps = 47/362 (12%)
Query: 1242 PGRSLIGLSGVLTVGSSRCLHSHAEALREKCVNCTRRFRCTQGFQLQDTP-RKSCVYRSG 1300
PG L G C S +CVN F+C+ Q TP R+ CV +
Sbjct: 1100 PGHELTA-KGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINE 1158
Query: 1301 FSFSRG-CSYTCAKKIQVPDCCPGFFGTLCEPCPGGLGGVCSGHGQCQDR---------- 1349
G C C C G +L G C+ +C++
Sbjct: 1159 CRVQNGGCDVHCINTEGSYRCSCGQGYSLMPD-----GRACADVDECEENPRVCDQGHCT 1213
Query: 1350 -FLGSGECHCHEGFHGTA-------CEVCELGRYGPNCTGVCDCAHGLCQEGLQGDGSCV 1401
G C C++GF T + C+L + C HG C E +G C
Sbjct: 1214 NMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPH--------ICLHGDC-ENTKGSFVCH 1264
Query: 1402 CNVGWQGLR----CDQKITSPQCPRKCDPNANCVQDSAGASTCACAAGYSGNGIFCSEVD 1457
C +G+ + C CD +A+C+ + G+ +C C G+ G+G C ++D
Sbjct: 1265 CQLGYMVRKGATGCSDVDECEVGGHNCDSHASCL-NIPGSFSCRCLPGWVGDGFECHDLD 1323
Query: 1458 PCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINSCLIHHGGCHIHAECIPT 1517
C CSP +C V PG CTC+ G+ GDG C++ + C + C + +C+
Sbjct: 1324 ECVSQEHRCSPRGDCLNV-PGSYRCTCRQGFAGDGFFCEDRDECAENVDLCD-NGQCL-N 1380
Query: 1518 GPQQVSCSCREGYS-GDGIRTCELLDPCSKNNGGCSPYATCKSTGDGQRTCTCDTAHTVG 1576
P C C G+ + R C+ +D C++ G + +C++ G C C+ + +
Sbjct: 1381 APGGYRCECEMGFDPTEDHRACQDVDECAQ--GNLCAFGSCENL-PGMFRCICNGGYELD 1437
Query: 1577 DG 1578
G
Sbjct: 1438 RG 1439
Score = 102 bits (253), Expect = 6e-21
Identities = 109/402 (27%), Positives = 151/402 (37%), Gaps = 80/402 (19%)
Query: 1241 APGRSLIGLSGVLTVGSSRCLHSHAEALREKCVNCTRRFRCT--QGFQLQDTPRKSCVYR 1298
A R ++GV + C +CVN FRC +G L + R R
Sbjct: 854 ACARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVR 913
Query: 1299 SGFSFSRG----CSYTCAKKIQVPDCCPGF---FGTLCEPCPG------------GLG-- 1337
F R C T K ++ CC +G CE CP GLG
Sbjct: 914 LEPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFA 973
Query: 1338 ---------------------GVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYG 1376
G+C+ HG C++ +GS C C GF A E
Sbjct: 974 SRDFLSGRPFYKDVNECKVFPGLCT-HGTCRNT-VGSFHCACAGGFALDAQE-------- 1023
Query: 1377 PNCTGVCDC--AHGLCQEGL----QGDGSCVCNVGWQG--LRCDQKITSPQCPRKCDP-- 1426
NCT + +C + LC +G G C C G++ + + +C R DP
Sbjct: 1024 RNCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECAR--DPLL 1081
Query: 1427 -NANCVQDSAGASTCACAAGY--SGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCT 1483
++ G+ C C G+ + G C ++D C+ G C PH C V G C+
Sbjct: 1082 CRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLC-PHGQCVNVI-GAFQCS 1139
Query: 1484 CQDGYMG--DGELCQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGYS--GDGIRTCE 1539
C G+ D + C +IN C + +GGC +H CI T CSC +GYS DG R C
Sbjct: 1140 CHAGFQSTPDRQGCVDINECRVQNGGCDVH--CINT-EGSYRCSCGQGYSLMPDG-RACA 1195
Query: 1540 LLDPCSKNNGGCSPYATCKSTGDGQRTCTCDTAHTVGDGLTC 1581
+D C +N C C + G R D D TC
Sbjct: 1196 DVDECEENPRVCD-QGHCTNMPGGHRCLCYDGFMATPDMRTC 1236
Score = 97.1 bits (240), Expect = 2e-19
Identities = 97/350 (27%), Positives = 136/350 (38%), Gaps = 57/350 (16%)
Query: 664 GSCVDCQALNTSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKGCASYCNQTIMEQGCCKG 723
G+CV+ C P + K C+ + + +L +G G C
Sbjct: 1042 GTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRG------------GTCTN 1089
Query: 724 FFGPDCTQCPGGFSNPCYGKG-------NCSDGIQGNGACLCFPDYKGIACH--ICSNPN 774
G QCP G G + SDG+ +G C+ +CH S P+
Sbjct: 1090 TDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPD 1149
Query: 775 KHGEQCQEDCGCVHGLCD----NRPGSGGVCQQGTCAPGFS----GRFCNESMGDCGPTG 826
+ G +C +G CD N GS + +C G+S GR C + + +C
Sbjct: 1150 RQGCVDINECRVQNGGCDVHCINTEGS----YRCSCGQGYSLMPDGRACAD-VDECEEN- 1203
Query: 827 LAQHCHLHARCVSQEGVARCRCLDGFEG--DGFSCTPSNPCS---HPDRGGCSENAECVP 881
+ C C + G RC C DGF D +C + C H G EN +
Sbjct: 1204 -PRVCD-QGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTK--- 1258
Query: 882 GSLGTHHCTCHKGWS--GDGRVCVAIDECELDMRGG--CHTDALCSYVGPGQSRCTCKLG 937
G+ C C G+ C +DECE+ GG C + A C + PG C C G
Sbjct: 1259 ---GSFVCHCQLGYMVRKGATGCSDVDECEV---GGHNCDSHASCLNI-PGSFSCRCLPG 1311
Query: 938 FAGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGFGGDGFSC 987
+ GDG++C +D C + C C V G R CTC GF GDGF C
Sbjct: 1312 WVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYR-CTCRQGFAGDGFFC 1360
Score = 96.3 bits (238), Expect = 3e-19
Identities = 79/267 (29%), Positives = 110/267 (41%), Gaps = 40/267 (14%)
Query: 738 NPCYGKGNCSDGIQGNGACLCFPDY----KGIACHICSNPNKHGEQCQEDCG-CVHGLCD 792
+P +G G+ C C P + KG AC ++C G C HG C
Sbjct: 1078 DPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDI-------DECSLSDGLCPHGQCV 1130
Query: 793 NRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQH-CHLHARCVSQEGVARCRCLDG 851
N G+ Q +C GF + D + C +H C++ EG RC C G
Sbjct: 1131 NVIGAF----QCSCHAGFQSTPDRQGCVDINECRVQNGGCDVH--CINTEGSYRCSCGQG 1184
Query: 852 FE--GDGFSCTPSNPCSHP----DRGGCSENAECVPGSLGTHHCTCHKGWSG--DGRVCV 903
+ DG +C + C D+G C+ +PG H C C+ G+ D R CV
Sbjct: 1185 YSLMPDGRACADVDECEENPRVCDQGHCTN----MPGG---HRCLCYDGFMATPDMRTCV 1237
Query: 904 AIDECELDMRGGCHTDALCSYVGPGQSRCTCKLGFA--GDGYQCSPIDPCRAGNGGCHGL 961
+DEC+L+ H D C G C C+LG+ CS +D C G C
Sbjct: 1238 DVDECDLNPHICLHGD--CENT-KGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSH 1294
Query: 962 ATCRAVGGGQRVCTCPPGFGGDGFSCY 988
A+C + G C C PG+ GDGF C+
Sbjct: 1295 ASCLNIPGSFS-CRCLPGWVGDGFECH 1320
Score = 84.3 bits (207), Expect = 1e-15
Identities = 80/295 (27%), Positives = 115/295 (38%), Gaps = 68/295 (23%)
Query: 1950 CVTT--TWKPSCCPGH-YGSECQACPGGPSSPCSDRGVCMDGMS----GSGQCLCRSGFA 2002
C T ++K C PGH ++ AC SD G+C G G+ QC C +GF
Sbjct: 1087 CTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSD-GLCPHGQCVNVIGAFQCSCHAGFQ 1145
Query: 2003 GT-----------------ACEL------------CAPG-AFGPHCQAC----RCTVHGR 2028
T C++ C G + P +AC C + R
Sbjct: 1146 STPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPR 1205
Query: 2029 -CDEG----LGGSGSCFCDEGWTG-PRCEVQLELQPVCTPPCAPEAVCRAGNS------- 2075
CD+G + G C C +G+ P +++ P +C G+
Sbjct: 1206 VCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNP----HICLHGDCENTKGSF 1261
Query: 2076 -CECSLGY--EGDGRVCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWSCRA 2132
C C LGY C+ D C+ G C HA+C + +C CLP + GDG+ C
Sbjct: 1262 VCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHD 1321
Query: 2133 RNPC-TDGHRGGCSEHANCLSTGLNTRRCECHAGYVGDGLQCLEESE--PPVDRC 2184
+ C + HR CS +CL+ + RC C G+ GDG C + E VD C
Sbjct: 1322 LDECVSQEHR--CSPRGDCLNVP-GSYRCTCRQGFAGDGFFCEDRDECAENVDLC 1373
Score = 82.8 bits (203), Expect = 4e-15
Identities = 93/377 (24%), Positives = 137/377 (36%), Gaps = 68/377 (18%)
Query: 1242 PGRSLIGLSGVLTVGSSRCLHSHAEALREKCVNCTRRFRCT--QGFQLQDTPRKSCVYRS 1299
PG + SG + C + +CVN FRC +GFQ T + R
Sbjct: 2238 PGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQ 2297
Query: 1300 GFSFSRGCSYTC------AKKIQVPDCCPGF---FGTLCEPCP------------GGLGG 1338
G F+ C ++ + +CC G +G CE CP G G
Sbjct: 2298 GPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGY 2357
Query: 1339 VCSG--------------HGQCQDRFLGSGECHCHEGFH----GTAC-EVCELGRYGPNC 1379
G HG+C + LGS CHC G+ T C ++ E + C
Sbjct: 2358 TAEGRDVDECRMLAHLCAHGECINS-LGSFRCHCQAGYTPDATATTCLDMDECSQVPKPC 2416
Query: 1380 TGVCDCAHGLCQEGLQGDGSCVCNVGW----QGLRCDQKITSPQCPRKCDPNANCVQDSA 1435
T +C + +G C C G+ G C C CV ++
Sbjct: 2417 TFLC--------KNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQ--FLCV-NTV 2465
Query: 1436 GASTCACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGY--MGDGE 1493
GA TC C G++ + C + D C+ G C H +C PG C C G+ + G
Sbjct: 2466 GAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHN-TPGSFRCECHQGFTLVSSGH 2524
Query: 1494 LCQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDG-IRTCELLDPCSKNNGGCS 1552
C+++N C G H CSC +G++ C + C+ + C
Sbjct: 2525 GCEDVNEC----DGPHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCG 2580
Query: 1553 PYATCKSTGDGQRTCTC 1569
A+C++T G R C C
Sbjct: 2581 S-ASCRNTLGGFR-CVC 2595
Score = 79.0 bits (193), Expect = 6e-14
Identities = 83/333 (24%), Positives = 129/333 (38%), Gaps = 39/333 (11%)
Query: 32 CDVKTTFVTHVPCTSCAAIKKQTCPSGWLRELPDQITQDCRYEVQLGGSMVSMSGCRRKC 91
C + H C + + +C +G+ + PD+ Q C V + V GC C
Sbjct: 1117 CSLSDGLCPHGQCVNVIGAFQCSCHAGF-QSTPDR--QGC---VDINECRVQNGGCDVHC 1170
Query: 92 --RKQVVQKACCPGYW----GSRCHECPGGAETP--CN-GHGTCLDGMDRNGTCVCQENF 142
+ + +C GY G C + E P C+ GH T + G R C+C + F
Sbjct: 1171 INTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHR---CLCYDGF 1227
Query: 143 RGSA-CQECQDPNRFGPDCQ-SVCSCVHGVCNHGPRGDGSCLCFAGYT---GPHCDQELP 197
+ + C D + +C + C+HG C + +G C C GY G ++
Sbjct: 1228 MATPDMRTCVDVD----ECDLNPHICLHGDCEN-TKGSFVCHCQLGYMVRKGATGCSDVD 1282
Query: 198 VCQE--LRCPQNTQCS--AEAPSCRCLPGYTQQGSECRAPNPCWPSP--CSLLAQCSVSP 251
C+ C + C + SCRCLPG+ G EC + C CS C P
Sbjct: 1283 ECEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVP 1342
Query: 252 KGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPGLVSINS 311
G +C C + + GDG C +D C +N+ C + L PG C C G
Sbjct: 1343 -GSYRCTCRQGFAGDGFFCEDRDECAENVDLCDNGQCL---NAPGGYRCECEMGFDPTED 1398
Query: 312 NASAGCFAFCSPFSCDRSATCQVTADGKTSCVC 344
+ + C+ + +C+ G C+C
Sbjct: 1399 HRACQDVDECAQGNLCAFGSCE-NLPGMFRCIC 1430
Score = 78.2 bits (191), Expect = 1e-13
Identities = 99/375 (26%), Positives = 141/375 (37%), Gaps = 88/375 (23%)
Query: 664 GSCVDCQALNTSTCPPNSVKLDIFPKECVYIH-DPTGLNVLKKGCA-SYCNQTIMEQGCC 721
G CV+ CP + LD + CV + +P L + C + + M+ CC
Sbjct: 883 GRCVNTAGSFRCECP-EGLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCC 941
Query: 722 K--GFFGPDCTQCPGG----FSNPC-YGKGNCS-DGIQGNGACLCFPDYKGIACHICSNP 773
+G +C CP F++ C G G S D + G P YK +
Sbjct: 942 SIGAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGR------PFYKDV-------- 987
Query: 774 NKHGEQCQEDCG-CVHGLCDNRPGS------GG---------------------VCQQGT 805
+C+ G C HG C N GS GG +C QGT
Sbjct: 988 ----NECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGT 1043
Query: 806 CA-----------PGFSGRFCNESMGDCGPTGLAQHCHLHAR---CVSQEGVARCRCLDG 851
C PG+ F M +C L R C + +G +C+C G
Sbjct: 1044 CVNTPGSFECECFPGYESGFM--LMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPG 1101
Query: 852 FE--GDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSG--DGRVCVAIDE 907
E G +C + CS D G + +CV +G C+CH G+ D + CV I+E
Sbjct: 1102 HELTAKGTACEDIDECSLSD--GLCPHGQCV-NVIGAFQCSCHAGFQSTPDRQGCVDINE 1158
Query: 908 CELDMRGGCHTDALCSYVGPGQSRCTCKLGFA--GDGYQCSPIDPCRAGNGGCHGLATCR 965
C + GGC + + G RC+C G++ DG C+ +D C C C
Sbjct: 1159 CRV-QNGGCDVHCINT---EGSYRCSCGQGYSLMPDGRACADVDECEENPRVC-DQGHCT 1213
Query: 966 AVGGGQRVCTCPPGF 980
+ GG R C C GF
Sbjct: 1214 NMPGGHR-CLCYDGF 1227
Score = 76.6 bits (187), Expect = 3e-13
Identities = 68/239 (28%), Positives = 92/239 (38%), Gaps = 27/239 (11%)
Query: 1945 GCHRNCVTT--TWKPSCCPGHY----GSECQACPGGPSSP-CSDRGVCMDGMSGSGQCLC 1997
GC +C+ T +++ SC G+ G C +P D+G C + M G +CLC
Sbjct: 1165 GCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTN-MPGGHRCLC 1223
Query: 1998 RSGFAGT----ACELCAPGAFGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWT---GPRC 2050
GF T C PH +HG C E GS C C G+ G
Sbjct: 1224 YDGFMATPDMRTCVDVDECDLNPHI-----CLHGDC-ENTKGSFVCHCQLGYMVRKGATG 1277
Query: 2051 EVQLELQPVCTPPCAPEAVCR---AGNSCECSLGYEGDGRVCTVADLCQDGHGGCSEHAN 2107
++ V C A C SC C G+ GDG C D C CS +
Sbjct: 1278 CSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGD 1337
Query: 2108 CSQVGTMVTCTCLPDYEGDGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGY 2166
C V CTC + GDG+ C R+ C + ++ CL+ RCEC G+
Sbjct: 1338 CLNVPGSYRCTCRQGFAGDGFFCEDRDECAE--NVDLCDNGQCLNAP-GGYRCECEMGF 1393
Score = 75.1 bits (183), Expect = 8e-13
Identities = 69/240 (28%), Positives = 92/240 (38%), Gaps = 32/240 (13%)
Query: 1272 CVNCTRRFRCT--QGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKKIQVPDC-CPGFFGTL 1328
C N F C+ +G+ L++ R S C + C + C CP F
Sbjct: 2420 CKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQH 2479
Query: 1329 CEPC-----PGGLGGVCSGHGQCQDRFLGSGECHCHEGF----HGTACEVCELGRYGPNC 1379
+ C G C HG C + GS C CH+GF G CE C
Sbjct: 2480 HQACFDNDECSAQPGPCGAHGHCHNT-PGSFRCECHQGFTLVSSGHGCEDVN------EC 2532
Query: 1380 TGVCDCAHGLCQEGLQGDGSCVCNVGW----QGLRCDQKITSPQCPRKCDPNANCVQDSA 1435
G C HG CQ L G C C G+ Q +C + P C +A+C +++
Sbjct: 2533 DGPHRCQHG-CQNQL-GGYRCSCPQGFTQHSQWAQCVDENECALSPPTCG-SASC-RNTL 2588
Query: 1436 GASTCACAAGYSGNGIF--CSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGE 1493
G C C +G+ + C EVD CA G CS +C PG C C GY G+
Sbjct: 2589 GGFRCVCPSGFDFDQALGGCQEVDECAGRRGPCS--YSCAN-TPGGFLCGCPQGYFRAGQ 2645
Score = 71.2 bits (173), Expect = 1e-11
Identities = 82/302 (27%), Positives = 110/302 (36%), Gaps = 50/302 (16%)
Query: 715 IMEQGCCKGFFGPDCTQCPGGFS------------------NPCYGKGNCSDGIQGNGAC 756
I G C G +CP GF+ +PC +C + I G+ C
Sbjct: 1731 ICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCIN-IPGSYRC 1789
Query: 757 LCFPDYKGIACHICSNPNKHGEQCQEDCG-CVHGLCDNRPGSGG-VCQQGTCAPGFSGRF 814
C YK C N +C+E C HG C + GS +C +G A
Sbjct: 1790 KCTRGYKLSPGGACVGRN----ECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLC 1845
Query: 815 CNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGF----EGDGFSCTPSNPCSHPDR 870
+ D P G + C + G C C GF GD C + C+
Sbjct: 1846 MDIDECDRQPCG-------NGTCKNIIGSYNCLCFPGFVVTHNGD---CVDFDECTTLVG 1895
Query: 871 GGCSENAECVPGSLGTHHCTCHKGW--SGDGRVCVAIDECELDMRGGCHTDALCSYVGPG 928
C C+ + G+ HC C G+ + DG+ CV +EC L + G C C + G
Sbjct: 1896 QVC-RFGHCL-NTAGSFHCLCQDGFELTADGKNCVDTNEC-LSLAGTC-LPGTCQNL-EG 1950
Query: 929 QSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGF--GGDGFS 986
RC C GF C ID C C TC G + C CPPGF +G
Sbjct: 1951 SFRCICPPGFQVQSDHCIDIDECSEEPNLCL-FGTCTNSPGSFQ-CLCPPGFVLSDNGHR 2008
Query: 987 CY 988
C+
Sbjct: 2009 CF 2010
Score = 70.1 bits (170), Expect = 3e-11
Identities = 89/364 (24%), Positives = 130/364 (35%), Gaps = 80/364 (21%)
Query: 654 CSEEQHKIVAGSCVDCQALNTSTCP-------PNSVKLDIFP--------KECVYIHDPT 698
C+ + V G C+D +S C P + +P + CV + +
Sbjct: 435 CNVGYTQDVRGECIDVDECTSSPCHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDE-- 492
Query: 699 GLNVLKKGCASYCNQTIMEQG-----CCKGF-FGPDCTQCPGGFSNPCYGKGNCSDGI-- 750
+ G + + + +G C GF PD C N C C +G+
Sbjct: 493 ---CIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVD--HNECATSTMCVNGVCL 547
Query: 751 --QGNGACLCFPDYK-GIACHICSNPNKHGEQCQEDCGCVHGLCDNRPGSGGVCQQGTCA 807
G+ +CLC P + H C + ++CQ CV+G C N GS G A
Sbjct: 548 NEDGSFSCLCKPGFLLAPGGHYCMDI----DECQTPGICVNGHCTNTEGSFRCQCLGGLA 603
Query: 808 PGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGDGFSCTPSN-PCS 866
G GR C ++ H R + + C F G + T S C+
Sbjct: 604 VGTDGRVCVDT---------------HVRSTCYGAIEKGSCARPFPG---TVTKSECCCA 645
Query: 867 HPDRGGCSENAECVPGSLGTHH---CTCHKGWSGDGRVCVAIDECELDMRGGCHTDALCS 923
+PD G E + P C+ G + DGR I+EC LD + +C
Sbjct: 646 NPDH-GFGEPCQLCPAKDSAEFQALCSSGLGITTDGR---DINECALDPE--VCANGVCE 699
Query: 924 YVGPGQSRCTCKLGF--AGDGYQCSPIDPCR-----AGNGGCHGLATCRAVGGGQRVCTC 976
+ G RC C LG+ G C+ +D C NG C G C+C
Sbjct: 700 NL-RGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQN-------SPGSYSCSC 751
Query: 977 PPGF 980
PPGF
Sbjct: 752 PPGF 755
Score = 70.1 bits (170), Expect = 3e-11
Identities = 67/239 (28%), Positives = 96/239 (40%), Gaps = 32/239 (13%)
Query: 1352 GSGECHCHEGFH---GTACEVCELGRYGPNCTGVCDCAHGLCQEGLQGDGSCVCNVGWQG 1408
GS C C G+ G AC R PN C+HG C + +G C+C+ G+Q
Sbjct: 1785 GSYRCKCTRGYKLSPGGACVGRNECREIPNV-----CSHGDCMD-TEGSYMCLCHRGFQA 1838
Query: 1409 LRCDQKITSP--QCPRKCDPNANCVQDSAGASTCACAAGY--SGNGIFCSEVDPCAHGHG 1464
DQ + +C R+ N C ++ G+ C C G+ + NG C + D C G
Sbjct: 1839 -SADQTLCMDIDECDRQPCGNGTC-KNIIGSYNCLCFPGFVVTHNGD-CVDFDECTTLVG 1895
Query: 1465 GCSPHANCTKVAPGQRTCTCQDGY--MGDGELCQEINSCLIHHGGCHIHAECIPTGPQQV 1522
+C A G C CQDG+ DG+ C + N CL + C+P Q +
Sbjct: 1896 QVCRFGHCLNTA-GSFHCLCQDGFELTADGKNCVDTNECL------SLAGTCLPGTCQNL 1948
Query: 1523 S----CSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKSTGDGQRTCTCDTAHTVGD 1577
C C G+ C +D CS+ C + TC + G C C + D
Sbjct: 1949 EGSFRCICPPGFQVQSDH-CIDIDECSEEPNLCL-FGTC-TNSPGSFQCLCPPGFVLSD 2004
Score = 69.3 bits (168), Expect = 5e-11
Identities = 99/396 (25%), Positives = 147/396 (37%), Gaps = 83/396 (20%)
Query: 1252 VLTVGSSRCLHSHAEALR---EKCVN---CTRRFRCTQGFQLQDTPRKSCVYRSGFSFSR 1305
V T GS +C+ + L + CV+ C C G L + SC+ + GF +
Sbjct: 506 VNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAP 565
Query: 1306 GCSYTC-AKKIQVPDCCPGFFGTLCE-----PCPGGL-----GGVCSG------------ 1342
G Y + Q P C T E C GGL G VC
Sbjct: 566 GGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIE 625
Query: 1343 HGQCQDRFLGS---GECHCHEGFHGTA--CEVC---ELGRYGPNCT---GVCD------- 1384
G C F G+ EC C HG C++C + + C+ G+
Sbjct: 626 KGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKDSAEFQALCSSGLGITTDGRDINE 685
Query: 1385 -------CAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITS-PQCPRK---CDPNANCVQD 1433
CA+G+C E L+G CVCN+G++ + T +C CD N C Q+
Sbjct: 686 CALDPEVCANGVC-ENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCD-NGWC-QN 742
Query: 1434 SAGASTCACAAGYS--GNGIFCSEVD-----PCAHGHGGCSPHANCTKVAPGQRT----C 1482
S G+ +C+C G+ + C +VD PC G + K PG R
Sbjct: 743 SPGSYSCSCPPGFHFWQDTEICKDVDECLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGT 802
Query: 1483 TCQDGYMGDGELCQEINSCLIHHGGCHIHAECI---------PTGPQQVSCSCREGYSGD 1533
C D G L + + C ++ G + +EC P ++ +C G++
Sbjct: 803 FCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFARM 862
Query: 1534 GIRTCELLDPCSKNNGGCSPYATCKSTGDGQRTCTC 1569
TC+ ++ C G C P C +T G C C
Sbjct: 863 TGVTCDDVNECESFPGVC-PNGRCVNTA-GSFRCEC 896
Score = 68.9 bits (167), Expect = 6e-11
Identities = 91/353 (25%), Positives = 117/353 (33%), Gaps = 88/353 (24%)
Query: 654 CSEEQHKIVAGSCVDCQALNTSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKGCASYCNQ 713
CSEE + + G+C + CPP V D C S+C
Sbjct: 1973 CSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSD-NGHRCFDTRQ------------SFC-F 2018
Query: 714 TIMEQGCCK--GFFGPDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICS 771
T E G C F T+C C G G G C +C
Sbjct: 2019 TRFEAGKCSVPKAFNTTKTRC-------------CCSKRPGEG--------WGDPCELC- 2056
Query: 772 NPNKHGEQCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHC 831
P + QE C HG S + C E+ G C
Sbjct: 2057 -PQEGSAAFQELCPFGHGAVPGPDDSREDVNE-----------CAENPGVC--------- 2095
Query: 832 HLHARCVSQEGVARCRCLDGFEGD--GFSCTPSNPCS--HPDRGGCSENAECVPGSLGTH 887
+ CV+ +G RC C G+ D G +C ++ CS HP G N +G
Sbjct: 2096 -TNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGTCTNV------IGGF 2148
Query: 888 HCTCHKGWS-GDGRVCVAIDECELDMRGGCHTDALCSY---VGPGQSRCTCKLGFA--GD 941
C C G+ G C IDEC L+ LC++ G CTC G+ D
Sbjct: 2149 ECACADGFEPGLMMTCEDIDECSLN-------PLLCAFRCHNTEGSYLCTCPAGYTLRED 2201
Query: 942 GYQCSPIDPCRAGNGGCHGLA-TCRAVGGGQRVCTCPPG---FGGDGFSCYGD 990
G C +D C G CH C+ + G C CPPG G G C D
Sbjct: 2202 GAMCRDVDECADGQQDCHARGMECKNL-IGTFACVCPPGMRPLPGSGEGCTDD 2253
Score = 68.6 bits (166), Expect = 8e-11
Identities = 84/314 (26%), Positives = 111/314 (35%), Gaps = 70/314 (22%)
Query: 1272 CVNCTRRFRCT--QGFQLQDTPRKSCVYRSGFSFSR----GCSYTCAKKIQVPDCC---- 1321
C N F+C GF L D + R F F+R CS A CC
Sbjct: 1985 CTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKR 2044
Query: 1322 PGF-FGTLCEPCPG------------GLG-------------------GVCSGHGQCQDR 1349
PG +G CE CP G G GVC+ +G C +
Sbjct: 2045 PGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCT-NGVCVNT 2103
Query: 1350 FLGSGECHCHEGFHGTACEVCELGRYGPNCTGVCDCAHGL-CQEG----LQGDGSCVCNV 1404
GS C C G+ L G NC +C+ G C +G + G C C
Sbjct: 2104 D-GSFRCECPFGY--------SLDFTGINCVDTDECSVGHPCGQGTCTNVIGGFECACAD 2154
Query: 1405 GWQG---LRCDQKITSPQCPRKCDPNANCVQDSAGASTCACAAGYS--GNGIFCSEVDPC 1459
G++ + C+ P C A ++ G+ C C AGY+ +G C +VD C
Sbjct: 2155 GFEPGLMMTCEDIDECSLNPLLC---AFRCHNTEGSYLCTCPAGYTLREDGAMCRDVDEC 2211
Query: 1460 AHGHGGCSPHANCTKVAPGQRTCTCQDGYM---GDGELCQEINSCLIHHGGCHIHAECIP 1516
A G C K G C C G G GE C + N C C ++ C+
Sbjct: 2212 ADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLC-VNGRCVN 2270
Query: 1517 TGPQQVSCSCREGY 1530
T C C EG+
Sbjct: 2271 TA-GSFRCDCDEGF 2283
Score = 68.6 bits (166), Expect = 8e-11
Identities = 74/286 (25%), Positives = 97/286 (33%), Gaps = 61/286 (21%)
Query: 721 CKGFFGPDCTQCPGGFSNPCYGKGNCSD----------GIQGNGACLCFPDY----KGIA 766
C+ + PD T + C CS +G+ C C Y G
Sbjct: 2390 CQAGYTPDAT------ATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRT 2443
Query: 767 CHICSNPNKHGEQCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRF--------CNES 818
C CQ LC N G+ C+ C PGF+ C+
Sbjct: 2444 CKDLDECTSRQHNCQF-------LCVNTVGAF-TCR---CPPGFTQHHQACFDNDECSAQ 2492
Query: 819 MGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFE--GDGFSCTPSNPCSHPDRGGCSEN 876
G CG G HCH + G RC C GF G C N C P R C
Sbjct: 2493 PGPCGAHG---HCH------NTPGSFRCECHQGFTLVSSGHGCEDVNECDGPHR--CQHG 2541
Query: 877 AECVPGSLGTHHCTCHKGWSGDGRVCVAIDECELDMRGGCHTDALCSYVGPGQSRCTCKL 936
+ LG + C+C +G++ + +DE E + A C G RC C
Sbjct: 2542 CQ---NQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNT-LGGFRCVCPS 2597
Query: 937 GFAGDGY--QCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGF 980
GF D C +D C G C +C GG +C CP G+
Sbjct: 2598 GFDFDQALGGCQEVDECAGRRGPCS--YSCANTPGG-FLCGCPQGY 2640
Score = 66.6 bits (161), Expect = 3e-10
Identities = 77/307 (25%), Positives = 112/307 (36%), Gaps = 58/307 (18%)
Query: 61 RELPDQITQDCRYEVQLGGSMVSMSGCRRKCRK--QVVQKACCPGYWGSRCHECPGGAET 118
RE P Q DC + + GS R KC + ++ C G + C E P
Sbjct: 1770 RESPCQQNADC---INIPGSY------RCKCTRGYKLSPGGACVGR--NECREIPNVCS- 1817
Query: 119 PCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHGVCNHGPR-- 176
HG C+D + + C+C F+ SA Q C + C C +G
Sbjct: 1818 ----HGDCMD-TEGSYMCLCHRGFQASADQTL---------CMDIDECDRQPCGNGTCKN 1863
Query: 177 --GDGSCLCFAGYTGPHCDQ--ELPVCQEL--RCPQNTQCSAEAPS--CRCLPGY--TQQ 226
G +CLCF G+ H + C L + + C A S C C G+ T
Sbjct: 1864 IIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTAD 1923
Query: 227 GSECRAPNPCWPSPCSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPSN 286
G C N C + L + +G +C CP + C+ D C++
Sbjct: 1924 GKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSDHCIDIDECSE-------E 1976
Query: 287 STLCVY----QKPGQAFCTCRPGLVSINSNASAGCF----AFC-SPFSCDRSATCQVTAD 337
LC++ PG C C PG V S+ CF +FC + F + + +
Sbjct: 1977 PNLCLFGTCTNSPGSFQCLCPPGFVL--SDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNT 2034
Query: 338 GKTSCVC 344
KT C C
Sbjct: 2035 TKTRCCC 2041
Score = 65.9 bits (159), Expect = 5e-10
Identities = 80/322 (24%), Positives = 108/322 (33%), Gaps = 52/322 (16%)
Query: 1272 CVNCTRRFRCT--QGFQLQDTPR-----KSCVYRSGFSFSRGCSYTCAKKIQVPDCCPGF 1324
CVN F+C G+ L + R C SG C P C
Sbjct: 1579 CVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSGI---------CG-----PGTCYNT 1624
Query: 1325 FGTLCEPCPGGLGGVCSGHGQCQDRFLG------SGECHCHEGFHGTACEVCELGRYGPN 1378
G CP V +G C D +G C F+ T C G
Sbjct: 1625 LGNYTCVCPAEYLQV-NGGNNCMDMRKSVCFRHYNGTCQNELAFNVTRKMCCCSYNIGQA 1683
Query: 1379 CTGVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSP-------QCPRKCDPNANCV 1431
C+ C + D +C G D P + P C N C+
Sbjct: 1684 WNRPCEA----CPTPISPDYQILCGNQAPGFLTDIHTGKPLDIDECGEIPAIC-ANGICI 1738
Query: 1432 QDSAGASTCACAAGYSGNGIF--CSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGY- 1488
+ G+ C C AG++ N I C +VD C C +A+C + PG C C GY
Sbjct: 1739 -NQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINI-PGSYRCKCTRGYK 1796
Query: 1489 MGDGELCQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRT-CELLDPCSKN 1547
+ G C N C C H +C+ T + C C G+ +T C +D C +
Sbjct: 1797 LSPGGACVGRNECREIPNVCS-HGDCMDTEGSYM-CLCHRGFQASADQTLCMDIDECDRQ 1854
Query: 1548 NGGCSPYATCKSTGDGQRTCTC 1569
G TCK+ G C C
Sbjct: 1855 PCG---NGTCKNI-IGSYNCLC 1872
Score = 65.1 bits (157), Expect = 9e-10
Identities = 73/298 (24%), Positives = 100/298 (33%), Gaps = 31/298 (10%)
Query: 697 PTGLNVLK---KGCAS----YCNQTIMEQGCCKGFFGPDCTQCPGGFSNPCYGKGNCSDG 749
P G+ L +GC + + G C G C GF P C D
Sbjct: 2237 PPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQ-PSPTLTECHDI 2295
Query: 750 IQGNGACLCFPDYKGIACHICSNPNKHGEQCQEDCGCVHGL---CDNRPGSGGVCQQGTC 806
QG CF + C S+ ++ + + CG G C+ P G + C
Sbjct: 2296 RQGP----CFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLC 2351
Query: 807 APGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGD--GFSCTPSNP 864
G + +C + H H C++ G RC C G+ D +C +
Sbjct: 2352 PHGSGYTAEGRDVDECR---MLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDE 2408
Query: 865 CSHPDRGGCSENAECVPGSLGTHHCTCHKGW--SGDGRVCVAIDECELDMRGGCHTDALC 922
CS + C+ + GS C+C +G+ DGR C +DEC H
Sbjct: 2409 CSQVPK-PCTFLCKNTKGSF---LCSCPRGYLLEEDGRTCKDLDECTSRQ----HNCQFL 2460
Query: 923 SYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGF 980
G C C GF C D C A G C C G R C C GF
Sbjct: 2461 CVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFR-CECHQGF 2517
Score = 64.7 bits (156), Expect = 1e-09
Identities = 93/386 (24%), Positives = 132/386 (34%), Gaps = 69/386 (17%)
Query: 10 LCLLAFCLAGFSFVRGQVLFKG---CDVKTTFVTHVPCTSCAAIKKQTCPSGWLRELPDQ 66
LC A F+ G+ +K C V TH C + C G+ + ++
Sbjct: 965 LCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQER 1024
Query: 67 ITQD---CRYEVQL--GGSMVSMSGCRRKCRKQVVQKACCPGYWGS-----RCHECPGGA 116
D CR L G+ V+ G + C PGY C + A
Sbjct: 1025 NCTDIDECRISPDLCGQGTCVNTPGS--------FECECFPGYESGFMLMKNCMDVDECA 1076
Query: 117 ETP--CNGHGTCLDGMDRNGTCVCQENF----RGSACQECQDPNRFGPDCQSVCSCVHGV 170
P C G GTC + D + C C +G+AC++ + CS G+
Sbjct: 1077 RDPLLCRG-GTCTN-TDGSYKCQCPPGHELTAKGTACEDIDE-----------CSLSDGL 1123
Query: 171 CNHGPR----GDGSCLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAPS------CRCL 220
C HG G C C AG+ Q E R QN C + C C
Sbjct: 1124 CPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRV-QNGGCDVHCINTEGSYRCSCG 1182
Query: 221 PGYT--QQGSECRAPNPCWPSP--CSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPC 276
GY+ G C + C +P C C+ P G +C C DG + P
Sbjct: 1183 QGYSLMPDGRACADVDECEENPRVCDQ-GHCTNMPGGH-RCLCY-----DGFMATPDMRT 1235
Query: 277 TDNLGGCPSNSTLCVY----QKPGQAFCTCRPGLVSINSNASAGCFAFCSP--FSCDRSA 330
++ C N +C++ G C C+ G + C +CD A
Sbjct: 1236 CVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHA 1295
Query: 331 TCQVTADGKTSCVCRESEVGDGRACY 356
+C + G SC C VGDG C+
Sbjct: 1296 SC-LNIPGSFSCRCLPGWVGDGFECH 1320
Score = 64.3 bits (155), Expect = 1e-09
Identities = 101/392 (25%), Positives = 140/392 (35%), Gaps = 97/392 (24%)
Query: 1255 VGSSRCLHSHAEALREKCVNCTRRFRCT-------QGFQLQDTPRKSCVYRSGFSFSRGC 1307
VG C SHA C+N F C GF+ D CV + RG
Sbjct: 1286 VGGHNC-DSHAS-----CLNIPGSFSCRCLPGWVGDGFECHDLDE--CVSQEHRCSPRG- 1336
Query: 1308 SYTCAKKIQVPDCC--PGFFGTLCEPCPGGLGGVCSGHGQCQDR--FLGSGECHCHEGFH 1363
DC PG + C G G C +C + +G+C G
Sbjct: 1337 -----------DCLNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLCDNGQCLNAPG-- 1383
Query: 1364 GTACEVCELGRYGPN-----CTGVCDCAHG-LCQ----EGLQGDGSCVCNVGWQGLRCDQ 1413
G CE CE+G + P C V +CA G LC E L G C+CN G++ R
Sbjct: 1384 GYRCE-CEMG-FDPTEDHRACQDVDECAQGNLCAFGSCENLPGMFRCICNGGYELDRGGG 1441
Query: 1414 KITSPQCPRKCDPNANCVQ----DSAGASTCACAAGYSGN--GIFCSE-------VDPCA 1460
T +C NC+ ++ G+ C+C + N G+ C + ++
Sbjct: 1442 NCTDIN---ECADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCVDTRAGNCFLETHD 1498
Query: 1461 HGHGGCSPHANCTKVAPGQRTCTCQDG--YMGDGELC----------------------- 1495
G G S A V + +C C G + ELC
Sbjct: 1499 RGDSGISCSAEIG-VGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLCPGGEGFQPNRI 1557
Query: 1496 ----QEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGYS-GDGIRTCELLDPCSKNNGG 1550
++I+ C G C +C+ T C C GY + R CE +D CS ++G
Sbjct: 1558 TVILEDIDECQELPGLCQ-GGDCVNTFGS-FQCECPPGYHLSEHTRICEDIDECSTHSGI 1615
Query: 1551 CSPYATCKSTGDGQRTCTCDTAH-TVGDGLTC 1581
C P TC +T G TC C + V G C
Sbjct: 1616 CGP-GTCYNT-LGNYTCVCPAEYLQVNGGNNC 1645
Score = 61.6 bits (148), Expect = 1e-08
Identities = 82/323 (25%), Positives = 114/323 (35%), Gaps = 69/323 (21%)
Query: 707 CASYCNQTIMEQGC-CKGFFGPDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGI 765
C T+ E G C+ D +C G C+ +G + G AC+C P + +
Sbjct: 2190 CTCPAGYTLREDGAMCR-----DVDECADG-QQDCHARGMECKNLIGTFACVCPPGMRPL 2243
Query: 766 ACHICSNPNKHGEQCQED--CG-----CVHGLCDNRPGSGGV-CQQGTCAPGFSGRFCNE 817
GE C +D C CV+G C N GS C +G P + C++
Sbjct: 2244 P--------GSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGF-QPSPTLTECHD 2294
Query: 818 -SMGDCGPTGLAQHCHLHARCVSQEGVARCRCL-DGFEGDGFSCT----PSNP-----CS 866
G C L C + S E V R C G G G C P C
Sbjct: 2295 IRQGPCFAEVLQTMCR--SLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCP 2352
Query: 867 HP--------DRGGCS------ENAECVPGSLGTHHCTCHKGWSGDGRV--CVAIDECEL 910
H D C + EC+ SLG+ C C G++ D C+ +DEC
Sbjct: 2353 HGSGYTAEGRDVDECRMLAHLCAHGECI-NSLGSFRCHCQAGYTPDATATTCLDMDECS- 2410
Query: 911 DMRGGCHTDALCSYV---GPGQSRCTCKLGFA--GDGYQCSPIDPCRAGNGGCHGLATCR 965
C+++ G C+C G+ DG C +D C + C L
Sbjct: 2411 ------QVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNT 2464
Query: 966 AVGGGQRVCTCPPGFGGDGFSCY 988
G C CPPGF +C+
Sbjct: 2465 V---GAFTCRCPPGFTQHHQACF 2484
Score = 60.1 bits (144), Expect = 3e-08
Identities = 93/349 (26%), Positives = 126/349 (36%), Gaps = 91/349 (26%)
Query: 1255 VGSSRCLHSHAEALREKCVNCTRRFRCT--QGFQLQDTPRKSCVYRSGFSFSRG-CSY-T 1310
V ++ CL L C N FRC GFQ+Q C+ S C + T
Sbjct: 1928 VDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSD---HCIDIDECSEEPNLCLFGT 1984
Query: 1311 CAKKIQVPDCCPGFFGTLCEPCPGGLGGVCSGHGQ---------CQDRFLGSGECHCHEG 1361
C PG F LC P G V S +G C RF +G+C +
Sbjct: 1985 CTNS-------PGSFQCLCPP-----GFVLSDNGHRCFDTRQSFCFTRF-EAGKCSVPKA 2031
Query: 1362 FHGTACEVCELGRYGPNCTGVCDCAHGLCQEGLQGDGSCVCNVGWQGLRC--DQKITSPQ 1419
F+ T C R G C+ LC + +C G + D + +
Sbjct: 2032 FNTTKTRCCCSKRPGEGWGDPCE----LCPQEGSAAFQELCPFGHGAVPGPDDSREDVNE 2087
Query: 1420 C---PRKCDPNANCVQDSAGASTCACAAGYSGN--GIFCSEVDPCAHGHGGCSPHANCTK 1474
C P C N CV ++ G+ C C GYS + GI C + D C+ GH C
Sbjct: 2088 CAENPGVCT-NGVCV-NTDGSFRCECPFGYSLDFTGINCVDTDECSVGHP-------C-- 2136
Query: 1475 VAPGQRTCTCQDGYMGDGELCQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDG 1534
GQ TCT +G E C+C +G+
Sbjct: 2137 ---GQGTCT---NVIGGFE------------------------------CACADGFEPGL 2160
Query: 1535 IRTCELLDPCSKNNGGCSPYATCKSTGDGQRTCTCDTAHTV-GDGLTCR 1582
+ TCE +D CS N C+ C +T +G CTC +T+ DG CR
Sbjct: 2161 MMTCEDIDECSLNPLLCA--FRCHNT-EGSYLCTCPAGYTLREDGAMCR 2206
Score = 58.9 bits (141), Expect = 6e-08
Identities = 84/295 (28%), Positives = 105/295 (35%), Gaps = 72/295 (24%)
Query: 1959 CCP--GHYGSECQACPGGPS---SPCSDRGV---CMDGMSG-------------SGQC-- 1995
CC +G EC+ACP S + RG+ D +SG G C
Sbjct: 940 CCSIGAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTH 999
Query: 1996 -LCRSGFAGTACELCAPGAFGPHCQACRCTVHGRC--DEGLGGSGSCFCDEGWTGPRC-- 2050
CR+ C CA G F Q CT C L G G+C G C
Sbjct: 1000 GTCRNTVGSFHC-ACA-GGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECECFP 1057
Query: 2051 --EVQLELQPVC--TPPCAPE-AVCRAGN--------SCECSLGYE--GDGRVCTVADLC 2095
E L C CA + +CR G C+C G+E G C D C
Sbjct: 1058 GYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDEC 1117
Query: 2096 QDGHGGCSEHANCSQVGTMVTCTC------LPDYEG--DGWSCRARNPCTDGHRGGCSEH 2147
G C H C V C+C PD +G D CR +N GGC H
Sbjct: 1118 SLSDGLC-PHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQN-------GGCDVH 1169
Query: 2148 ANCLSTGLNTRRCECHAGY--VGDGLQCLEESEPPVDRCLGQPPPCHSDAMCTDL 2200
C++T + RC C GY + DG C + VD C P C CT++
Sbjct: 1170 --CINTE-GSYRCSCGQGYSLMPDGRACAD-----VDECEENPRVC-DQGHCTNM 1215
Score = 58.9 bits (141), Expect = 6e-08
Identities = 88/353 (24%), Positives = 126/353 (35%), Gaps = 53/353 (15%)
Query: 32 CDVKTTFVTHVPCTSCAAIKKQTCPSGWLRELPDQITQDCRYEVQLGGSM--VSMSGCRR 89
C + + C + A + C G+ P +C ++++ G V + CR
Sbjct: 2256 CHAQPDLCVNGRCVNTAGSFRCDCDEGFQ---PSPTLTEC-HDIRQGPCFAEVLQTMCRS 2311
Query: 90 --KCRKQVVQKACCPGY---WGSRCHECP----GGAETPC-NGHGTCLDGMD-------- 131
+ V + CC G WG RC CP C +G G +G D
Sbjct: 2312 LSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLA 2371
Query: 132 ---RNGTCVCQENFRGSACQECQDPNRFGPDCQSV--CSCVHGVCNH---GPRGDGSCLC 183
+G C+ CQ P+ C + CS V C +G C C
Sbjct: 2372 HLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSC 2431
Query: 184 FAGYT----GPHCDQELPVC--QELRCPQNTQCSAEAPSCRCLPGYTQQGSECRAPNPC- 236
GY G C ++L C ++ C + A +CRC PG+TQ C + C
Sbjct: 2432 PRGYLLEEDGRTC-KDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDECS 2490
Query: 237 -WPSPCSLLAQCSVSPKGQAQCHCPENYH--GDGMVCLPKDPCTDNLGGCPSNSTLCVYQ 293
P PC C +P G +C C + + G C + C D C C Q
Sbjct: 2491 AQPGPCGAHGHCHNTP-GSFRCECHQGFTLVSSGHGCEDVNEC-DGPHRCQHG---CQNQ 2545
Query: 294 KPGQAFCTCRPGLVSINSNASAGCFAFC--SPFSCDRSATCQVTADGKTSCVC 344
G C+C G + A C SP +C SA+C+ T G CVC
Sbjct: 2546 LGGYR-CSCPQGFTQHSQWAQCVDENECALSPPTCG-SASCRNTLGG-FRCVC 2595
Score = 57.0 bits (136), Expect = 2e-07
Identities = 48/159 (30%), Positives = 63/159 (39%), Gaps = 28/159 (17%)
Query: 833 LHARCVSQEGVARCRCLDGFEG-------DGFSCTPSNPCSHPDRGGCSENAECVPGSLG 885
L+ RC+ RC C G+ D CT S+PC H D CV G
Sbjct: 420 LNGRCLPTPSSYRCECNVGYTQDVRGECIDVDECT-SSPCHHGD---------CV-NIPG 468
Query: 886 THHCTCHKGWSG--DGRVCVAIDECELDMRGGCHTDALCSYVGPGQSRCTCKLGF--AGD 941
T+HC C+ G+ + CV +DEC + G CH + G Q C C GF + D
Sbjct: 469 TYHCRCYPGFQATPTRQACVDVDEC-IVSGGLCHLGRCVNTEGSFQ--CVCNAGFELSPD 525
Query: 942 GYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGF 980
G C + C +G+ G C C PGF
Sbjct: 526 GKNCVDHNECATSTMCVNGVCLNE---DGSFSCLCKPGF 561
Score = 57.0 bits (136), Expect = 2e-07
Identities = 108/420 (25%), Positives = 137/420 (32%), Gaps = 118/420 (28%)
Query: 1966 SECQACPGGPSSPCSDRGVCMDGMSGSGQCLCRSGFAGTACELCAPGAFGPHCQACRCTV 2025
+EC+ PG G C + + GS C C GFA A E + C
Sbjct: 988 NECKVFPG-----LCTHGTCRNTV-GSFHCACAGGFALDAQE-----------RNCTDID 1030
Query: 2026 HGRCDEGLGGSGSCFCDEGWTGPRC----EVQLELQPVC--TPPCAPEAV-CRAGN---- 2074
R L G G+C G C E L C CA + + CR G
Sbjct: 1031 ECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNT 1090
Query: 2075 ----SCECSLGYE--GDGRVCTVADLCQDGHGGCSEHANCSQVGTMVTCTC------LPD 2122
C+C G+E G C D C G C H C V C+C PD
Sbjct: 1091 DGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCP-HGQCVNVIGAFQCSCHAGFQSTPD 1149
Query: 2123 YEG--DGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGY--VGDGLQCLE--- 2175
+G D CR +N GGC H C++T + RC C GY + DG C +
Sbjct: 1150 RQGCVDINECRVQN-------GGCDVH--CINTE-GSYRCSCGQGYSLMPDGRACADVDE 1199
Query: 2176 -ESEPPV---DRCLGQPPP----CHSDAMCTD------------------LHFQ---EKR 2206
E P V C P C+ M T LH K
Sbjct: 1200 CEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKG 1259
Query: 2207 AGVFHLQ----ATSGPYGLN-FSEAEAA---CEAQGAVLASFPQLSAAQQLGFHLCLMGW 2258
+ V H Q G G + E E C++ + L S CL GW
Sbjct: 1260 SFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCR-------CLPGW 1312
Query: 2259 LANGSTAHPVVFPVADCGNGRVGIVSLGARKNLSERWDAYCFRVQ-DVACRCRNGFVGDG 2317
+ +G H + +C + S R D C V C CR GF GDG
Sbjct: 1313 VGDGFECHDL----DEC---------VSQEHRCSPRGD--CLNVPGSYRCTCRQGFAGDG 1357
Score = 55.5 bits (132), Expect = 7e-07
Identities = 78/316 (24%), Positives = 100/316 (31%), Gaps = 93/316 (29%)
Query: 1941 GLGRGCHRNCVTTTWKPSCCPGHYGSECQACPGGPSSPCSDRGVCMDGMSGSGQC---LC 1997
G GR R P+ C + + C CPG + P G QC +C
Sbjct: 41 GPGRVRRRGSPGILQGPNVCGSRFHAYC--CPGWRTFP------------GRSQCVVPIC 86
Query: 1998 RSGFAGTACE-----LCAPGAFGPHCQACR---CTVHGRCDEGLGGSGSCFCDEGWTGPR 2049
R C CA G P C R C+V + G SC C +G+TG
Sbjct: 87 RRACGEGFCSQPNLCTCADGTLAPSCGVSRGSGCSV-SCMNGGTCRGASCLCQKGYTGTV 145
Query: 2050 CEVQLELQPVCTPPCAPEAVCRAGNSCECSLGYEG---DGRVCTVADLCQDGHGGCSEHA 2106
C QP+C C C N C C G+ G + T Q G GC +H
Sbjct: 146 CG-----QPICDRGCHNGGRCIGPNRCACVYGFMGPQCERDYRTGPCFGQVGPEGC-QHQ 199
Query: 2107 NCSQVGTMVTCTCLPDYEGDGWS-----CRAR-NPCTDG-----HRGGCSEHANCLSTGL 2155
V T C G W C A+ +PC G H G C +
Sbjct: 200 LTGLVCTKALCCAT---VGRAWGLPCELCPAQPHPCRRGFIPNIHTGACQD--------- 247
Query: 2156 NTRRCECHAGYVGDGLQCLEESEPPVDRCLGQPPPCHSDAMCTDLHFQEKRAGVFHLQAT 2215
VD C P C + C ++ G FH +
Sbjct: 248 -------------------------VDECQAVPGLCQGGS-CVNM------VGSFHCRC- 274
Query: 2216 SGPYGLNFSEAEAACE 2231
P G S++ AACE
Sbjct: 275 --PVGHRLSDSSAACE 288
Score = 55.1 bits (131), Expect = 9e-07
Identities = 82/336 (24%), Positives = 105/336 (31%), Gaps = 76/336 (22%)
Query: 1940 QGLGRGCHRNCVTTTWKPSCCPGH--YGSECQACPGGPSSPCSDRGVCMDGMS----GSG 1993
Q + R + T CC G +G C+ CP +S + R +C G G
Sbjct: 2306 QTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTS--AYRKLCPHGSGYTAEGRD 2363
Query: 1994 QCLCRSGFAGTACELCAPG-------AFGPHCQA--------CRCTVHGRCDE------- 2031
CR LCA G +F HCQA C C +
Sbjct: 2364 VDECRM-----LAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTF 2418
Query: 2032 ---GLGGSGSCFCDEGWT----GPRCEVQLEL---QPVCTPPCAPEAVCRAGNSCECSLG 2081
GS C C G+ G C+ E Q C C +C C G
Sbjct: 2419 LCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTV---GAFTCRCPPG 2475
Query: 2082 YEGDGRVCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPDYE--GDGWSCRARNPCTDG 2139
+ + C D C G C H +C C C + G C N C
Sbjct: 2476 FTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDGP 2535
Query: 2140 HR--GGCSEHANCLSTGLNTRRCECHAGYV--GDGLQCLEESEPPVDRCLGQPPPCHSDA 2195
HR GC L RC C G+ QC++E+E C PP C S A
Sbjct: 2536 HRCQHGCQNQ-------LGGYRCSCPQGFTQHSQWAQCVDENE-----CALSPPTCGS-A 2582
Query: 2196 MCTDLHFQEKRAGVFHLQATSGPYGLNFSEAEAACE 2231
C G F P G +F +A C+
Sbjct: 2583 SC------RNTLGGFRCVC---PSGFDFDQALGGCQ 2609
Score = 54.3 bits (129), Expect = 2e-06
Identities = 60/220 (27%), Positives = 80/220 (36%), Gaps = 60/220 (27%)
Query: 1943 GRGC--HRNCVTT--TWKPSCCPGHYGS--ECQACPGGPSSP--CSDRGVCMDGMSGSGQ 1994
G C H +C+ ++ C PG G EC S CS RG C++ + GS +
Sbjct: 1288 GHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLN-VPGSYR 1346
Query: 1995 CLCRSGFAGTACELCAPGAFGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQL 2054
C CR GFAG G F C C E + CD G
Sbjct: 1347 CTCRQGFAGD-------GFF--------CEDRDECAENVD-----LCDNG---------- 1376
Query: 2055 ELQPVCTPPCAPEAVCRAGNSCECSLGYE--GDGRVCTVADLCQDGHGGCSEHANCSQVG 2112
Q + P G CEC +G++ D R C D C G +C +
Sbjct: 1377 --QCLNAP---------GGYRCECEMGFDPTEDHRACQDVDEC--AQGNLCAFGSCENLP 1423
Query: 2113 TMVTCTCLPDYEGDGWSCRARNPCTDGHRGGCSEHANCLS 2152
M C C YE D R CTD + C++ NC++
Sbjct: 1424 GMFRCICNGGYELD----RGGGNCTDINE--CADPVNCIN 1457
Score = 52.8 bits (125), Expect = 4e-06
Identities = 74/291 (25%), Positives = 99/291 (34%), Gaps = 63/291 (21%)
Query: 720 CCKGFFG-PDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGE 778
CC G+ P +QC G+G CS C C +C + G
Sbjct: 68 CCPGWRTFPGRSQCVVPICRRACGEGFCSQP----NLCTCADGTLAPSCGV-----SRGS 118
Query: 779 QCQEDCGCVHGLCDNRPGSGGVCQQGTCA--PGFSGRFCNESMGDCGPTGLAQHCHLHAR 836
C C +GG C+ +C G++G C + + D G CH R
Sbjct: 119 GCSVSCM-----------NGGTCRGASCLCQKGYTGTVCGQPICDRG-------CHNGGR 160
Query: 837 CVSQEGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWS 896
C+ G RC C+ GF G C R G C G +G C
Sbjct: 161 CI---GPNRCACVYGFMGP--------QCERDYRTG-----PCF-GQVGPEGCQHQL--- 200
Query: 897 GDGRVCVAIDECELDMRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQ--CSPIDPCRAG 954
G VC C R LC P Q C+ GF + + C +D C+A
Sbjct: 201 -TGLVCTKALCCATVGRAWGLPCELC----PAQPH-PCRRGFIPNIHTGACQDVDECQAV 254
Query: 955 NGGCHGLATCRAVGGGQRVCTCPPGFGGDGFSCYGDIFRELEANAHFSIFY 1005
G C G + VG C CP G S + +R A A FS+ +
Sbjct: 255 PGLCQGGSCVNMVGSFH--CRCPVGHRLSDSSAACEDYR---AGACFSVLF 300
Score = 52.4 bits (124), Expect = 6e-06
Identities = 53/205 (25%), Positives = 73/205 (35%), Gaps = 17/205 (8%)
Query: 1385 CAHGLCQEGLQGDGSCVCNVGWQG----LRCDQKITSPQCPRKCDPNANCVQDSAGASTC 1440
CA+G+C + G C C G+ L C+ C NA+C+ + G+ C
Sbjct: 1732 CANGICINQI-GSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCI-NIPGSYRC 1789
Query: 1441 ACAAGYS-GNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMG--DGELCQE 1497
C GY G C + C CS H +C G C C G+ D LC +
Sbjct: 1790 KCTRGYKLSPGGACVGRNECREIPNVCS-HGDCMDTE-GSYMCLCHRGFQASADQTLCMD 1847
Query: 1498 INSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATC 1557
I+ C G I + +C C G+ C D C+ G + C
Sbjct: 1848 IDECDRQPCGNGTCKNIIGS----YNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHC 1903
Query: 1558 KSTGDGQRTCTC-DTAHTVGDGLTC 1581
+T G C C D DG C
Sbjct: 1904 LNTA-GSFHCLCQDGFELTADGKNC 1927
Score = 52.4 bits (124), Expect = 6e-06
Identities = 85/343 (24%), Positives = 123/343 (35%), Gaps = 59/343 (17%)
Query: 666 CVDCQALNTSTCPPNSVKLDIFPKECV----YIHDPTGLNVLKKGCASYCNQTIMEQGCC 721
C+D + C + K I C+ ++ G V C + Q + G C
Sbjct: 1845 CMDIDECDRQPCGNGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQ-VCRFGHC 1903
Query: 722 KGFFGPDCTQCPGGFSNPCYGK------------GNCSDG----IQGNGACLCFPDYKGI 765
G C GF GK G C G ++G+ C+C P ++
Sbjct: 1904 LNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQ 1963
Query: 766 ACHICSNPNKHGEQCQEDCG-CVHGLCDNRPGSGGVCQQGTCAPGF----SGRFCNESMG 820
+ H ++C E+ C+ G C N PGS Q C PGF +G C ++
Sbjct: 1964 SDHCIDI-----DECSEEPNLCLFGTCTNSPGSF----QCLCPPGFVLSDNGHRCFDTRQ 2014
Query: 821 D-CGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAEC 879
C A C + + + RC C G+G+ +PC + G + E
Sbjct: 2015 SFCFTRFEAGKCSVPKAFNTTK--TRC-CCSKRPGEGWG----DPCELCPQEGSAAFQEL 2067
Query: 880 VPGSLGTHHCTCHKGWSGDGRVCVAIDECELDMRGGCHTDALCSYVGPGQSRCTCKLGFA 939
P H G ++EC + G C T+ +C G RC C G++
Sbjct: 2068 CPFG--------HGAVPGPDDSREDVNECA-ENPGVC-TNGVCVNTD-GSFRCECPFGYS 2116
Query: 940 GD--GYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGF 980
D G C D C G+ C G TC V GG C C GF
Sbjct: 2117 LDFTGINCVDTDECSVGH-PC-GQGTCTNVIGGFE-CACADGF 2156
Score = 51.2 bits (121), Expect = 1e-05
Identities = 65/260 (25%), Positives = 90/260 (34%), Gaps = 57/260 (21%)
Query: 1954 TWKPSCC----PGH-YGSECQACPG------------------GPS------SPCSDR-G 1983
T K CC PG +G C+ CP GP + C++ G
Sbjct: 2034 TTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPG 2093
Query: 1984 VCMDGM----SGSGQCLCRSG----FAGTACELCAPGAFGPHCQACRCTVHGRCDEGLGG 2035
VC +G+ GS +C C G F G C + G C G C +GG
Sbjct: 2094 VCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCG------QGTCTNVIGG 2147
Query: 2036 SGSCFCDEGWTGPRCEVQLELQPVCTPP--CAPEAVCRAGNS-CECSLGY--EGDGRVCT 2090
C C +G+ ++ P CA G+ C C GY DG +C
Sbjct: 2148 F-ECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCR 2206
Query: 2091 VADLCQDGHGGC-SEHANCSQVGTMVTCTCLPDYE---GDGWSCRARNPCTDGHRGGCSE 2146
D C DG C + C + C C P G G C N C +
Sbjct: 2207 DVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNEC--HAQPDLCV 2264
Query: 2147 HANCLSTGLNTRRCECHAGY 2166
+ C++T + RC+C G+
Sbjct: 2265 NGRCVNTA-GSFRCDCDEGF 2283
Score = 50.8 bits (120), Expect = 2e-05
Identities = 57/250 (22%), Positives = 88/250 (35%), Gaps = 30/250 (12%)
Query: 1957 PSCCPGHYGSECQACP-------GGPSSPCSDRGVCMDGMSGSGQCLCRSGFAGT----A 2005
P C G+ CP GG + + VC +G+ C F T
Sbjct: 1618 PGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGT--CQNELAFNVTRKMCC 1675
Query: 2006 CELCAPGAFGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQL--ELQPVCTPP 2063
C A+ C+AC + G F + TG ++ E+ +C
Sbjct: 1676 CSYNIGQAWNRPCEACPTPISPDYQILCGNQAPGFLTDIHTGKPLDIDECGEIPAICANG 1735
Query: 2064 CAPEAVCRAGNSCECSLGYEGDGRV--CTVADLCQDGHGGCSEHANCSQVGTMVTCTCLP 2121
+ CEC G+ + + C D C C ++A+C + C C
Sbjct: 1736 ICINQI--GSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTR 1793
Query: 2122 DYE-GDGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGY--VGDGLQCLEESE 2178
Y+ G +C RN C + CS H +C+ T + C CH G+ D C++
Sbjct: 1794 GYKLSPGGACVGRNECRE-IPNVCS-HGDCMDTE-GSYMCLCHRGFQASADQTLCMD--- 1847
Query: 2179 PPVDRCLGQP 2188
+D C QP
Sbjct: 1848 --IDECDRQP 1855
Score = 50.4 bits (119), Expect = 2e-05
Identities = 70/273 (25%), Positives = 88/273 (32%), Gaps = 54/273 (19%)
Query: 1315 IQVPDCCPGFFGTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGF--HGTACEVCEL 1372
+Q P+ C F C CPG G QC C EGF C C
Sbjct: 54 LQGPNVCGSRFHAYC--CPGWR--TFPGRSQCVVPICRRA---CGEGFCSQPNLC-TCAD 105
Query: 1373 GRYGPNCTGVC---DCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNAN 1429
G P+C GV C+ G SC+C G+ G C Q P C R C
Sbjct: 106 GTLAPSC-GVSRGSGCSVSCMNGGTCRGASCLCQKGYTGTVCGQ----PICDRGCHNGGR 160
Query: 1430 CVQDSAGASTCACAAGYSGNGIFCS---EVDPCAHGHGGCSPHANCTKVAPGQRTCTCQD 1486
C+ G + CAC G+ G C PC G P CQ
Sbjct: 161 CI----GPNRCACVYGFMGPQ--CERDYRTGPC---FGQVGPEG-------------CQ- 197
Query: 1487 GYMGDGELCQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRT--CELLDPC 1544
+ G +C + C + E P P CR G+ I T C+ +D C
Sbjct: 198 -HQLTGLVCTKALCCATVGRAWGLPCELCPAQPH----PCRRGFI-PNIHTGACQDVDEC 251
Query: 1545 SKNNGGCSPYATCKSTGDGQRTCTCDTAHTVGD 1577
G C + G C C H + D
Sbjct: 252 QAVPGLCQGGSCVNMVGSFH--CRCPVGHRLSD 282
Score = 49.7 bits (117), Expect = 4e-05
Identities = 79/327 (24%), Positives = 117/327 (35%), Gaps = 43/327 (13%)
Query: 1272 CVNCTRRF--RCTQGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKKI-----QVPDCCPGF 1324
CVN F RC G +L D+ YR+G FS CA + + CC
Sbjct: 263 CVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAGDLAGHYTRRQCCCDRG 322
Query: 1325 FGTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGR--YGPNCTGV 1382
P P +C G + + L + G G + G GP
Sbjct: 323 RCWAAGPVPE----LCPPRGSNEFQQLCAQRLPLLPGHPGLFPGLLGFGSNGMGPPLGPA 378
Query: 1383 CDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTCAC 1442
HG G+ G N+G L +Q I + N C+ + + C C
Sbjct: 379 RLNPHGSDARGIPSLGPGNSNIGTATL--NQTIDICRHFTNLCLNGRCLP-TPSSYRCEC 435
Query: 1443 AAGYSGNGIF-CSEVDPCAHGHGGCSP--HANCTKVAPGQRTCTCQDGYMGDG--ELCQE 1497
GY+ + C +VD C SP H +C + PG C C G+ + C +
Sbjct: 436 NVGYTQDVRGECIDVDECTS-----SPCHHGDCVNI-PGTYHCRCYPGFQATPTRQACVD 489
Query: 1498 INSCLIHHGGCHIHAECIPTGPQQVSCSCREGY--SGDGIRTCELLDPCSKN----NGGC 1551
++ C++ G CH+ C+ T C C G+ S DG + C + C+ + NG C
Sbjct: 490 VDECIVSGGLCHL-GRCVNT-EGSFQCVCNAGFELSPDG-KNCVDHNECATSTMCVNGVC 546
Query: 1552 SPYATCKSTGDGQRTCTCDTAHTVGDG 1578
DG +C C + G
Sbjct: 547 -------LNEDGSFSCLCKPGFLLAPG 566
Score = 48.1 bits (113), Expect = 1e-04
Identities = 84/347 (24%), Positives = 114/347 (32%), Gaps = 120/347 (34%)
Query: 31 GCDVKTTFVTHVPCTSCAAIKKQTCPSGWLRELPDQITQDCRYEVQLGGSMVSMSGCRRK 90
G D + THV T AI+K +C R P +T+
Sbjct: 605 GTDGRVCVDTHVRSTCYGAIEKGSC----ARPFPGTVTK--------------------- 639
Query: 91 CRKQVVQKACC--PGY-WGSRCHECPG--GAETPC---NGHGTCLDGMD----------- 131
+ CC P + +G C CP AE +G G DG D
Sbjct: 640 ------SECCCANPDHGFGEPCQLCPAKDSAEFQALCSSGLGITTDGRDINECALDPEVC 693
Query: 132 RNGTCVCQENFRGS---ACQECQDPNRFGPDCQSVCSCV-------HGVCNHGPRGDGSC 181
NG C EN RGS C + G DC V C +G C + P G SC
Sbjct: 694 ANGVC---ENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSP-GSYSC 749
Query: 182 LCFAGYTGPHCDQELPVCQELRCPQNTQC-------SAEAPSCRCLPG------------ 222
C G+ H Q+ +C+++ ++ C A + +C+C PG
Sbjct: 750 SCPPGF---HFWQDTEICKDVDECLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLD 806
Query: 223 ----------------YTQQG----SECRAP-NPCWPSPCSLLAQCSVSPKGQAQCHCPE 261
QG SEC A W SPC +C + P C
Sbjct: 807 STKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGSPCE---RCEIDPA------CAR 857
Query: 262 NY-HGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPGLV 307
+ G+ C + C G CP+ CV G C C GL+
Sbjct: 858 GFARMTGVTCDDVNECESFPGVCPNGR--CV-NTAGSFRCECPEGLM 901
Score = 47.8 bits (112), Expect = 1e-04
Identities = 36/117 (30%), Positives = 50/117 (42%), Gaps = 13/117 (11%)
Query: 876 NAECVPGSLGTHHCTCHKGWSGDGR-VCVAIDECELDMRGGCHTDALCSYVGPGQSRCTC 934
N C+P + ++ C C+ G++ D R C+ +DEC CH + PG C C
Sbjct: 421 NGRCLP-TPSSYRCECNVGYTQDVRGECIDVDECT---SSPCHHGDCVNI--PGTYHCRC 474
Query: 935 KLGFAGDGYQ--CSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGF--GGDGFSC 987
GF + C +D C G CH L C G + C C GF DG +C
Sbjct: 475 YPGFQATPTRQACVDVDECIVSGGLCH-LGRCVNTEGSFQ-CVCNAGFELSPDGKNC 529
Score = 47.0 bits (110), Expect = 2e-04
Identities = 70/256 (27%), Positives = 80/256 (31%), Gaps = 65/256 (25%)
Query: 102 PGYWGSRCHE--CPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPN----- 154
P GSR H CPG P G C+ + R C E F C PN
Sbjct: 57 PNVCGSRFHAYCCPGWRTFP--GRSQCVVPICRRA---CGEGF-------CSQPNLCTCA 104
Query: 155 --RFGPDC--QSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQELPVCQE-----LRCP 205
P C C N G SCLC GYTG C Q P+C RC
Sbjct: 105 DGTLAPSCGVSRGSGCSVSCMNGGTCRGASCLCQKGYTGTVCGQ--PICDRGCHNGGRCI 162
Query: 206 QNTQCSA----EAPSC----RCLPGYTQQGSE----------------CRAPNPCWPSPC 241
+C+ P C R P + Q G E C W PC
Sbjct: 163 GPNRCACVYGFMGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPC 222
Query: 242 SLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCT 301
L C P + P + G C D C G C S CV G C
Sbjct: 223 EL---CPAQPHPCRRGFIPNIHTG---ACQDVDECQAVPGLCQGGS--CV-NMVGSFHCR 273
Query: 302 CRPGLVSINSNASAGC 317
C G S++SA C
Sbjct: 274 CPVG--HRLSDSSAAC 287
Score = 47.0 bits (110), Expect = 2e-04
Identities = 70/287 (24%), Positives = 97/287 (33%), Gaps = 43/287 (14%)
Query: 712 NQTIMEQGCCKGFFGPDCTQCPGGFS-----NPCYGKGNCSDG-IQGNGACLCFPDYKGI 765
N + + G C G +C GF C C+ G + G+C P
Sbjct: 1369 NVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLPGMFRC 1428
Query: 766 ACHICSNPNKHG------EQCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESM 819
C+ ++ G +C + C++G+C N PGS +C +C F N S
Sbjct: 1429 ICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGS-YLC---SCPQDFE---LNPSG 1481
Query: 820 GDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGDGFSCTPS------NPCSHPDRGGC 873
C T A +C L G++ C G SC S NPC
Sbjct: 1482 VGCVDT-RAGNCFLETHDRGDSGIS-CSAEIGVGVTRASCCCSLGRAWGNPCELCPMANT 1539
Query: 874 SENAECVPGSLGTHHCTCHKGWSGDGRVCVA---IDECELDMRGGCHTDALCSYVGPGQS 930
+E PG G R+ V IDEC+ ++ G C + G Q
Sbjct: 1540 TEYRTLCPGGEGFQ----------PNRITVILEDIDECQ-ELPGLCQGGDCVNTFGSFQC 1588
Query: 931 RCTCKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCP 977
C + C ID C +G C G TC G C CP
Sbjct: 1589 ECPPGYHLSEHTRICEDIDECSTHSGIC-GPGTCYNTLGNY-TCVCP 1633
Score = 45.4 bits (106), Expect = 7e-04
Identities = 82/322 (25%), Positives = 100/322 (31%), Gaps = 87/322 (27%)
Query: 1948 RNCVTT--------TWKPSCCPGHYGSECQACPGG---PSSPCSDRGVCMD--------- 1987
+NCV T T P C GS CP G S C D C +
Sbjct: 1925 KNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSDHCIDIDECSEEPNLCLFGT 1984
Query: 1988 --GMSGSGQCLCRSGFA----GTACELCAPGAFGPHCQACRCTVHGRCDEGLGGSGSCFC 2041
GS QCLC GF G C +A +C+V + C C
Sbjct: 1985 CTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTT---KTRCCC 2041
Query: 2042 D----EGWTGPRCEV-----QLELQPVC----------------------TPPCAPEAVC 2070
EGW P CE+ Q +C P VC
Sbjct: 2042 SKRPGEGWGDP-CELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTNGVC 2100
Query: 2071 RAGNS---CECSLGYEGD--GRVCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPDYE- 2124
+ CEC GY D G C D C GH C + C+ V C C +E
Sbjct: 2101 VNTDGSFRCECPFGYSLDFTGINCVDTDECSVGH-PCGQ-GTCTNVIGGFECACADGFEP 2158
Query: 2125 GDGWSCRARNPCTDGHRGGCSEHANCLSTGLNTR---RCECHAGYV--GDGLQCLEESEP 2179
G +C + C+ C NT C C AGY DG C +
Sbjct: 2159 GLMMTCEDIDECS-------LNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRD---- 2207
Query: 2180 PVDRCLGQPPPCHSDAM-CTDL 2200
VD C CH+ M C +L
Sbjct: 2208 -VDECADGQQDCHARGMECKNL 2228
Score = 45.4 bits (106), Expect = 7e-04
Identities = 55/231 (23%), Positives = 76/231 (32%), Gaps = 50/231 (21%)
Query: 98 KACC---PGY-WGSRCHECPGGAETPCNGHGTCLDGMDRNGTCVCQE--NFRGSACQECQ 151
+ CC PG WG C CP + G+ QE F A
Sbjct: 2038 RCCCSKRPGEGWGDPCELCP------------------QEGSAAFQELCPFGHGAVPGPD 2079
Query: 152 DPNRFGPDC-QSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQELPVCQELRCPQNTQC 210
D +C ++ C +GVC + G C C GY+ + C +C
Sbjct: 2080 DSREDVNECAENPGVCTNGVCVNTD-GSFRCECPFGYSLDFTG--------INCVDTDEC 2130
Query: 211 SAEAPSCRCLPGYTQQGSECRAPNPCWPS---PCSLLAQCSVSP----------KGQAQC 257
S P + G EC + P C + +CS++P +G C
Sbjct: 2131 SVGHPCGQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLC 2190
Query: 258 HCPENY--HGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPGL 306
CP Y DG +C D C D C + C G C C PG+
Sbjct: 2191 TCPAGYTLREDGAMCRDVDECADGQQDCHARGMEC-KNLIGTFACVCPPGM 2240
Score = 44.7 bits (104), Expect = 0.001
Identities = 55/230 (23%), Positives = 80/230 (34%), Gaps = 43/230 (18%)
Query: 1979 CSDRGVCMDGMSGSGQCLCRSGFAGTACELCA---------PGAF-----------GPHC 2018
C DRG C +G LC + +LCA PG F GP
Sbjct: 318 CCDRGRCW--AAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGLFPGLLGFGSNGMGPPL 375
Query: 2019 QACRCTVHGRCDEGLG--GSGSCFCDEGWTGPRCEVQLELQPVC-TPPCAPEAVCRAGNS 2075
R HG G+ G G+ ++ +C C P +
Sbjct: 376 GPARLNPHGSDARGIPSLGPGNSNIGTATLNQTIDICRHFTNLCLNGRCLPTP---SSYR 432
Query: 2076 CECSLGYEGDGR-VCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWSCRARN 2134
CEC++GY D R C D C H +C + C C P ++ + R
Sbjct: 433 CECNVGYTQDVRGECIDVDECTSSP---CHHGDCVNIPGTYHCRCYPGFQ----ATPTRQ 485
Query: 2135 PCTDGHR----GGCSEHANCLSTGLNTRRCECHAGY--VGDGLQCLEESE 2178
C D GG C++T + +C C+AG+ DG C++ +E
Sbjct: 486 ACVDVDECIVSGGLCHLGRCVNTE-GSFQCVCNAGFELSPDGKNCVDHNE 534
Score = 44.7 bits (104), Expect = 0.001
Identities = 45/179 (25%), Positives = 62/179 (34%), Gaps = 25/179 (13%)
Query: 135 TCVCQENF--RGSACQECQDPNRFGPDCQSVCSCVHGVCNHGPRGDGSCLCFAGYT---- 188
TC C F AC + + + C + HG C++ P G C C G+T
Sbjct: 2469 TCRCPPGFTQHHQACFDNDECSAQPGPCGA-----HGHCHNTP-GSFRCECHQGFTLVSS 2522
Query: 189 GPHCDQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQ--QGSECRAPNPCWPSPCSLLAQ 246
G C+ RC Q C C G+TQ Q ++C N C SP + +
Sbjct: 2523 GHGCEDVNECDGPHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSA 2582
Query: 247 CSVSPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPG 305
+ G +C CP + D LGGC + P C PG
Sbjct: 2583 SCRNTLGGFRCVCPSGFDFD-----------QALGGCQEVDECAGRRGPCSYSCANTPG 2630
Score = 43.9 bits (102), Expect = 0.002
Identities = 80/339 (23%), Positives = 105/339 (30%), Gaps = 80/339 (23%)
Query: 712 NQTIMEQGCCKGFFGPDCTQCPGGF----------------SNPCYGKGNCSDGIQGNGA 755
N + + G C+ G CP GF S+PC G C + + G+
Sbjct: 731 NSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSPCVS-GVCRN-LAGSYT 788
Query: 756 CLCFP----DYKGIACHICSNP-------------NKHGEQCQEDCGCVHGLCDNRPGSG 798
C C P D G C + N G + +C G P
Sbjct: 789 CKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGSPCER 848
Query: 799 GVCQ-QGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDG--FEGD 855
C+ CA GF+ R + D + RCV+ G RC C +G +
Sbjct: 849 --CEIDPACARGFA-RMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDAS 905
Query: 856 GFSCTP--SNPCSHPDRGGCSENAECVPGSLGTHHCTCHKG--WSGDGRVC---VAIDEC 908
G C PC R E +PG C C G W + C +++
Sbjct: 906 GRLCVDVRLEPCFL--RWDEDECGVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFA 963
Query: 909 ELDMRG-------------------------GCHTDALCSYVGPGQSRCTCKLGFAGDGY 943
L RG G T C G C C GFA D
Sbjct: 964 SLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGTCRNT-VGSFHCACAGGFALDAQ 1022
Query: 944 Q--CSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGF 980
+ C+ ID CR C G TC G C C PG+
Sbjct: 1023 ERNCTDIDECRISPDLC-GQGTCVNTPGSFE-CECFPGY 1059
Score = 43.5 bits (101), Expect = 0.003
Identities = 44/170 (25%), Positives = 61/170 (35%), Gaps = 32/170 (18%)
Query: 111 ECPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHGV 170
EC G PC G GTC + + C C + F C+D + CS +
Sbjct: 2129 ECSVGH--PC-GQGTCTNVIG-GFECACADGFEPGLMMTCEDIDE--------CSLNPLL 2176
Query: 171 CN---HGPRGDGSCLCFAGYTGPHCDQELPVCQEL-RCPQNTQ-CSAEAPSCR------- 218
C H G C C AGYT ++ +C+++ C Q C A C+
Sbjct: 2177 CAFRCHNTEGSYLCTCPAGYT---LREDGAMCRDVDECADGQQDCHARGMECKNLIGTFA 2233
Query: 219 --CLPGYTQ---QGSECRAPNPCWPSPCSLLAQCSVSPKGQAQCHCPENY 263
C PG G C N C P + V+ G +C C E +
Sbjct: 2234 CVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGF 2283
Score = 42.4 bits (98), Expect = 0.006
Identities = 81/354 (22%), Positives = 111/354 (31%), Gaps = 104/354 (29%)
Query: 1943 GRGC--HRNCVTTTWKPS-CCPGHYGS-ECQACPGGPSSP----------CSDRGVCMDG 1988
G+ C H C T+T + C GS C PG +P C G+C++G
Sbjct: 526 GKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNG 585
Query: 1989 ----MSGSGQCLCRSGFA-GTACELCAPGAFGPHCQACRCTVHGRCDEGLGGS---GSCF 2040
GS +C C G A GT +C C G C G+ C
Sbjct: 586 HCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGA--IEKGSCARPFPGTVTKSECC 643
Query: 2041 C---DEGWTGPRCEV-----QLELQPVCT------------------PPCAPEAVC---R 2071
C D G+ P C++ E Q +C+ P VC R
Sbjct: 644 CANPDHGFGEP-CQLCPAKDSAEFQALCSSGLGITTDGRDINECALDPEVCANGVCENLR 702
Query: 2072 AGNSCECSLGYEG--DGRVCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPDYE--GDG 2127
C C+LGYE G+ CT D C C ++ C +C+C P + D
Sbjct: 703 GSYRCVCNLGYEAGASGKDCTDVDECALNSLLC-DNGWCQNSPGSYSCSCPPGFHFWQDT 761
Query: 2128 WSCRARNPCTDGH--RGGCSEHANCLSTGLNTRRCECHAGYVGDGLQCLEESEPPVDRCL 2185
C+ + C G C A + C+C G +P
Sbjct: 762 EICKDVDECLSSPCVSGVCRNLAGSYT-------CKCGPG---------SRLDP------ 799
Query: 2186 GQPPPCHSDAMCTDLHFQEKRAGVFHLQATSGPYGLNFSEAEAACEAQGAVLAS 2239
+G F L +T G L E+ QGA L S
Sbjct: 800 ---------------------SGTFCLDSTKGTCWLKIQESRCEVNLQGASLRS 832
Score = 40.4 bits (93), Expect = 0.023
Identities = 70/288 (24%), Positives = 107/288 (37%), Gaps = 56/288 (19%)
Query: 1942 LGRGCHRNC-----VTTTWKPSCCPGHYGSECQACPGGPSSPCSDRGVCMD--GMSGSGQ 1994
LGR C TT + CPG G + P + D C + G+ G
Sbjct: 1523 LGRAWGNPCELCPMANTTEYRTLCPGGEGFQ----PNRITVILEDIDECQELPGLCQGGD 1578
Query: 1995 CLCRSGFAGTACELCAPGA-FGPHCQACR----CTVHGRCDEGLGGSGSCFCDEGWTGPR 2049
C+ + F CE C PG H + C C+ H G+ G G+C+ G
Sbjct: 1579 CV--NTFGSFQCE-CPPGYHLSEHTRICEDIDECSTHS----GICGPGTCYNTLGNYTCV 1631
Query: 2050 CEVQLELQPVCTPPCAP--EAVC--RAGNSCECSLGYEGDGRVCTVADLCQDGHGGCSEH 2105
C + LQ C ++VC +C+ L + ++C C + G + +
Sbjct: 1632 CPAEY-LQVNGGNNCMDMRKSVCFRHYNGTCQNELAFNVTRKMC-----CCSYNIGQAWN 1685
Query: 2106 ANCSQVGTMVTCTCLPDYEGDGWSCRARNP--CTDGHRGG------CSEHANCLSTGL-- 2155
C T ++ PDY+ C + P TD H G C E + G+
Sbjct: 1686 RPCEACPTPIS----PDYQ---ILCGNQAPGFLTDIHTGKPLDIDECGEIPAICANGICI 1738
Query: 2156 ---NTRRCECHAGYVGDGLQCLEESEPPVDRCLGQPPPCHSDAMCTDL 2200
+ RCEC AG+ + + E VD C + PC +A C ++
Sbjct: 1739 NQIGSFRCECPAGFNYNSILLACED---VDECGSRESPCQQNADCINI 1783
Score = 39.7 bits (91), Expect = 0.039
Identities = 61/262 (23%), Positives = 85/262 (32%), Gaps = 41/262 (15%)
Query: 55 CPSGWLRELPDQITQDCRYEVQL---GGSMVSMSGCRRKCRKQVVQKACCPGYWGSRCHE 111
C G LP C +L GG+ ++ C C GS
Sbjct: 1414 CAFGSCENLPGMFRCICNGGYELDRGGGNCTDINECADPVN---CINGVCINTPGSYLCS 1470
Query: 112 CPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHGVC 171
CP E +G G C+D R G C + + RG + C G S C C
Sbjct: 1471 CPQDFELNPSGVG-CVD--TRAGNCFLETHDRGDSGISCSAEIGVGVTRASCC------C 1521
Query: 172 NHGPRGDGSC-LCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQGSEC 230
+ G C LC T + P + + + T + C+ LPG Q G +C
Sbjct: 1522 SLGRAWGNPCELCPMANTTEYRTL-CPGGEGFQPNRITVILEDIDECQELPGLCQ-GGDC 1579
Query: 231 RAPNPCWPSPCSLLAQCSVSPKGQAQCHCPENYH--GDGMVCLPKDPCTDNLGGCPSNST 288
V+ G QC CP YH +C D C+ + G C +
Sbjct: 1580 ------------------VNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSGICGPGT- 1620
Query: 289 LCVYQKPGQAFCTCRPGLVSIN 310
Y G C C + +N
Sbjct: 1621 --CYNTLGNYTCVCPAEYLQVN 1640
Score = 37.7 bits (86), Expect = 0.15
Identities = 65/254 (25%), Positives = 92/254 (36%), Gaps = 65/254 (25%)
Query: 1983 GVCMDGMSGSGQCLCRSGFAGTACELCAPGAFGPHCQACRCTVHGRCDEG----LGGSGS 2038
G C++ +GS CLC+ GF EL A G C ++ G C G L GS
Sbjct: 1901 GHCLN-TAGSFHCLCQDGF-----ELTADGKNCVDTNEC-LSLAGTCLPGTCQNLEGSFR 1953
Query: 2039 CFCDEGWTGPRCEVQLELQPVCTPPCAPEA-VCRAGN--------SCECSLGY--EGDGR 2087
C C G+ +VQ + + C+ E +C G C C G+ +G
Sbjct: 1954 CICPPGF-----QVQSD-HCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGH 2007
Query: 2088 VC--TVADLC--QDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGW-----------SCRA 2132
C T C + G CS + T C+ P G+GW S
Sbjct: 2008 RCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRP---GEGWGDPCELCPQEGSAAF 2064
Query: 2133 RNPCTDGHR------------GGCSEHANCLSTGL-----NTRRCECHAGYVGD--GLQC 2173
+ C GH C+E+ + G+ + RCEC GY D G+ C
Sbjct: 2065 QELCPFGHGAVPGPDDSREDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINC 2124
Query: 2174 LEESEPPVDRCLGQ 2187
++ E V GQ
Sbjct: 2125 VDTDECSVGHPCGQ 2138
>gi|14192943 multiple EGF-like-domains 10 [Homo sapiens]
Length = 1140
Score = 103 bits (256), Expect = 3e-21
Identities = 96/313 (30%), Positives = 124/313 (39%), Gaps = 63/313 (20%)
Query: 1257 SSRCLHSHAEALREKCVNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRGC----SYTCA 1312
+ RC SHA+ C T RC G+ R G + S C +C+
Sbjct: 539 AERCDCSHADG----CHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCS 594
Query: 1313 KKIQVPDCCPGFFGTLCEPC--PGGLGGVCSGHGQCQDRFLGSGECH-------CHEGFH 1363
+ +C PGF GT C+ PG G CS C SG CH C GF
Sbjct: 595 PDDGICECAPGFRGTTCQRICSPGFYGHRCSQ--TCPQCVHSSGPCHHITGLCDCLPGFT 652
Query: 1364 GTAC-EVCELGRYGPNCTGVCDCA-HGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCP 1421
G C EVC GR+G NC G+C C +G C D SC C GW G C Q
Sbjct: 653 GALCNEVCPSGRFGKNCAGICTCTNNGTCN---PIDRSCQCYPGWIGSDCSQPCPPAHWG 709
Query: 1422 RKCDPNANCVQD---SAGASTCACAAGYSGNGIFCSEVDPCAHGHGG--------CSPHA 1470
C NC SA C C G++ G++C++ C G G C A
Sbjct: 710 PNCIHTCNCHNGAFCSAYDGECKCTPGWT--GLYCTQ--RCPLGFYGKDCALICQCQNGA 765
Query: 1471 NCTKVAPGQRTCTCQDGYMGD-----------GELCQEINSCLIHHGGCHIHAECIPTGP 1519
+C ++ GQ CTC+ G+MG G C++I CL + HI TG
Sbjct: 766 DCDHIS-GQ--CTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHI------TG- 815
Query: 1520 QQVSCSCREGYSG 1532
+C C G+ G
Sbjct: 816 ---TCYCSPGWKG 825
Score = 102 bits (254), Expect = 5e-21
Identities = 103/401 (25%), Positives = 142/401 (35%), Gaps = 101/401 (25%)
Query: 1247 IGLSGVLTVGSSRCLHSHAEALREKCVNCTRRFRCTQGFQLQDTPRKSC---VYRSGFSF 1303
+G GVL + +C++ KC + + C GF + + C +Y G
Sbjct: 313 VGTYGVLCAETCQCVNGG------KCYHVSGACLCEAGFAGERCEARLCPEGLY--GIKC 364
Query: 1304 SRGC------SYTCAKKIQVPDCCPGFFGTLC-EPC-PGGLGGVCSGHGQCQ---DRFLG 1352
+ C +++C C PG+ G C E C PG G C CQ D
Sbjct: 365 DKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSV 424
Query: 1353 SGECHCHEGFHGTACEV-CELGRYGPNCTGVCDCAHGLCQEGLQGDGSCVCNVGWQGLRC 1411
+G+C C GF G C C LG YG NC+ C C + + DGSC C GW G+ C
Sbjct: 425 TGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPV--DGSCTCKAGWHGVDC 482
Query: 1412 DQKITSPQCPRKCDPNANCVQDSAGAS---TCACAAGYSGN-----------GIFCSEVD 1457
+ S C+ C+ A + TC CA G+ G G+ C+E
Sbjct: 483 SIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERC 542
Query: 1458 PCAHGHG------------------------------------------GCSPHANCTKV 1475
C+H G CSP +
Sbjct: 543 DCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICEC 602
Query: 1476 APGQRTCTCQ----DGYMGDGELCQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGYS 1531
APG R TCQ G+ G Q C+ G CH H TG C C G++
Sbjct: 603 APGFRGTTCQRICSPGFYGH-RCSQTCPQCVHSSGPCH-HI----TG----LCDCLPGFT 652
Query: 1532 GDGIRTCELLDPCSKNNGGCSPYATCKSTGDG---QRTCTC 1569
G C + P + C+ TC + G R+C C
Sbjct: 653 G---ALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQC 690
Score = 101 bits (252), Expect = 8e-21
Identities = 104/365 (28%), Positives = 142/365 (38%), Gaps = 71/365 (19%)
Query: 653 HCSEEQHKIVAGSCVDCQALNTSTCPP--------NSVKLDIFPKECVYIHDPTGLNVLK 704
HC++ K V G C+ A NT C P ++ D + C T K
Sbjct: 108 HCAD---KCVHGRCI---APNTCQCEPGWGGTNCSSACDGDHWGPHC------TSRCQCK 155
Query: 705 KGCASYCNQTIMEQGCCKGFFGPDCT-QCPGG-FSNPCYGKGNCSDGIQGN---GACLCF 759
G + CN C GF G C +C G + N C+ + C +G + G C C
Sbjct: 156 NG--ALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGECRCP 213
Query: 760 PDYKGIACHICSNPNKHGEQCQEDCGCVHGLCDNRPGSGGVCQQGT----CAPGFSGRFC 815
P Y G C P KHG QC++ C C +GGVC T C G+ G C
Sbjct: 214 PGYTGAFCEDLCPPGKHGPQCEQRCPC---------QNGGVCHHVTGECSCPSGWMGTVC 264
Query: 816 NESMGDCGPTG--LAQHCHLHARCVSQEGVARCRCLDGFEGDGFSCTPSNPCSHPDRGG- 872
+ + G G +Q C H +C C G+ G+ C + C G
Sbjct: 265 GQPCPE-GRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGE--RC--QDECPVGTYGVL 319
Query: 873 CSENAECVPGSLGTH---HCTCHKGWSG---DGRVC-VAIDECELDMRGGCHTDALCSYV 925
C+E +CV G H C C G++G + R+C + + D R CH + S
Sbjct: 320 CAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHS-C 378
Query: 926 GPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGG--------CHGLATCRAVGGGQRVCTCP 977
P C CK G++ G C+ + C G G C A C +V G CTC
Sbjct: 379 HPMSGECACKPGWS--GLYCN--ETCSPGFYGEACQQICSCQNGADCDSVTG---KCTCA 431
Query: 978 PGFGG 982
PGF G
Sbjct: 432 PGFKG 436
Score = 98.2 bits (243), Expect = 9e-20
Identities = 86/304 (28%), Positives = 115/304 (37%), Gaps = 52/304 (17%)
Query: 1320 CCPGFFGTLCEP-CPGGL-GGVCSGHGQCQDRFLG---SGECHCHEGFHGTACE-VCELG 1373
C GF G CE C G G C QCQ+ +GEC C G+ G CE +C G
Sbjct: 169 CAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGYTGAFCEDLCPPG 228
Query: 1374 RYGPNCTGVCDCAH-GLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQ 1432
++GP C C C + G+C G C C GW G C Q + + C C
Sbjct: 229 KHGPQCEQRCPCQNGGVCH---HVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHN 285
Query: 1433 D---SAGASTCACAAGYSGN-----------GIFCSEVDPCAHGHGGCSPHANCTKVAPG 1478
A C C+ GY+G G+ C+E C +G C V+
Sbjct: 286 GGTCDAATGQCHCSPGYTGERCQDECPVGTYGVLCAETCQCVNG-------GKCYHVS-- 336
Query: 1479 QRTCTCQDGYMG---DGELCQEINSCLIHHGGCHIHAECIPT-GPQQVSCSCREGYSGDG 1534
C C+ G+ G + LC E + C H E + P C+C+ G+S G
Sbjct: 337 -GACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGECACKPGWS--G 393
Query: 1535 IRTCELLDP----------CSKNNGGCSPYATCKST-GDGQRTCTCDTAHTVGD-GLTCR 1582
+ E P CS NG T K T G + C T +G G+ C
Sbjct: 394 LYCNETCSPGFYGEACQQICSCQNGADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCS 453
Query: 1583 ARVG 1586
+R G
Sbjct: 454 SRCG 457
Score = 97.1 bits (240), Expect = 2e-19
Identities = 91/348 (26%), Positives = 126/348 (36%), Gaps = 67/348 (19%)
Query: 1262 HSHAEALREKCVNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKKIQVPDCC 1321
H + C + F+CT R YR+ + Y +K Q CC
Sbjct: 50 HPFDQIYYTSCTDILNWFKCT---------RHRVSYRTAYRHGEKTMYR--RKSQ---CC 95
Query: 1322 PGFF--GTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACE-VCELGRYGPN 1378
PGF+ G +C P C HG+C + C C G+ GT C C+ +GP+
Sbjct: 96 PGFYESGEMCVP---HCADKCV-HGRC----IAPNTCQCEPGWGGTNCSSACDGDHWGPH 147
Query: 1379 CTGVCDCAHG-LCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSA-- 1435
CT C C +G LC G+C C G++G RC+ + C C +
Sbjct: 148 CTSRCQCKNGALCN---PITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCD 204
Query: 1436 -GASTCACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRT---CTCQDGYMGD 1491
C C GY+ G FC ++ P C C C+C G+MG
Sbjct: 205 HVTGECRCPPGYT--GAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMGT 262
Query: 1492 --GELCQE-------INSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLD 1542
G+ C E C H+GG A TG C C GY+G+ C+ D
Sbjct: 263 VCGQPCPEGRFGKNCSQECQCHNGGTCDAA----TG----QCHCSPGYTGE---RCQ--D 309
Query: 1543 PCSKNNGGCSPYATCKSTGDGQ-----RTCTCDTAHTVGDGLTCRARV 1585
C G TC+ G+ C C+ G C AR+
Sbjct: 310 ECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFA---GERCEARL 354
Score = 94.7 bits (234), Expect = 1e-18
Identities = 79/278 (28%), Positives = 107/278 (38%), Gaps = 51/278 (18%)
Query: 100 CCPGYWGSRCHE-CPGGAE-TPCNGHGTCLDGMDRN---GTCVCQENFRGSACQECQDPN 154
C G+ G RC + C G C+ C +G + G C C + G+ C++ P
Sbjct: 169 CAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGYTGAFCEDLCPPG 228
Query: 155 RFGPDCQSVCSCVH-GVCNHGPRGDGSCLCFAGYTGPHCDQELP-------VCQELRCPQ 206
+ GP C+ C C + GVC+H G C C +G+ G C Q P QE +C
Sbjct: 229 KHGPQCEQRCPCQNGGVCHH---VTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHN 285
Query: 207 NTQCSAEAPSCRCLPGYTQQGSECRAPNPCWPSPCSLLAQCSVSPK-----GQAQCH--- 258
C A C C PGYT + + P + C+ QC K G C
Sbjct: 286 GGTCDAATGQCHCSPGYTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGF 345
Query: 259 ---------CPENYHGDGMVCLPKDPC-TDNLGGCPSNSTLCVYQKPGQA--FC--TCRP 304
CPE + G+ C + PC +N C S C KPG + +C TC P
Sbjct: 346 AGERCEARLCPEGLY--GIKCDKRCPCHLENTHSCHPMSGECAC-KPGWSGLYCNETCSP 402
Query: 305 GLVSINSNASAGCFAFCSPFSCDRSATCQVTADGKTSC 342
G C C SC A C + GK +C
Sbjct: 403 GFY------GEACQQIC---SCQNGADCD-SVTGKCTC 430
Score = 94.7 bits (234), Expect = 1e-18
Identities = 102/368 (27%), Positives = 123/368 (33%), Gaps = 108/368 (29%)
Query: 654 CSEEQHKIVAGSCVDCQALNTSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKGCASYCNQ 713
C E + I C NT +C P S EC +GL YCN+
Sbjct: 355 CPEGLYGIKCDKRCPCHLENTHSCHPMS-------GECACKPGWSGL---------YCNE 398
Query: 714 TIMEQGCCKGFFGPDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNP 773
T C GF+G C Q C +C D + G C C P +KGI C
Sbjct: 399 T-----CSPGFYGEACQQICS-----CQNGADC-DSVTGK--CTCAPGFKGIDCSTPCPL 445
Query: 774 NKHGEQCQEDCGC--------VHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPT 825
+G C CGC V G C + G GV C G G CN
Sbjct: 446 GTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCN--------- 496
Query: 826 GLAQHCHLHARCVSQEGVARCRCLDGFEGD-----------GFSCTPSNPCSHPDRGGCS 874
L C C + +G C C G+ G+ G +C CSH D GC
Sbjct: 497 -LTCQCLNGGACNTLDGT--CTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHAD--GCH 551
Query: 875 ENAECVPGSLGTHHCTCHKGWSGDGRVCVAIDECELDMRGG--------CHTDALCSYVG 926
T HC C GWSG V D + R G C A CS
Sbjct: 552 PT---------TGHCRCLPGWSG-----VHCDSVCAEGRWGPNCSLPCYCKNGASCS--- 594
Query: 927 PGQSRCTCKLGFAGD-----------GYQCSPIDP-CRAGNGGCHGLATCRAVGGGQRVC 974
P C C GF G G++CS P C +G CH + +C
Sbjct: 595 PDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHIT---------GLC 645
Query: 975 TCPPGFGG 982
C PGF G
Sbjct: 646 DCLPGFTG 653
Score = 94.0 bits (232), Expect = 2e-18
Identities = 74/260 (28%), Positives = 95/260 (36%), Gaps = 51/260 (19%)
Query: 87 CRRKCRKQVVQKACCPGYWGSRCHE-CPGGAET--PCNGHGTCLDGMDRNGTCVCQENFR 143
C R Q+ C PG++G RC + CP + PC+ H T G C C F
Sbjct: 602 CAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCH-HIT--------GLCDCLPGFT 652
Query: 144 GSACQECQDPNRFGPDCQSVCSCVH-GVCNHGPRGDGSCLCFAGYTGPHCDQELPVCQ-- 200
G+ C E RFG +C +C+C + G CN R SC C+ G+ G C Q P
Sbjct: 653 GALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDR---SCQCYPGWIGSDCSQPCPPAHWG 709
Query: 201 -----ELRCPQNTQCSAEAPSCRCLPGYTQQGSECRAPNPCWPSPCSLLAQCSVSP---- 251
C CSA C+C PG+T R P + C+L+ QC
Sbjct: 710 PNCIHTCNCHNGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDH 769
Query: 252 -KGQAQCH-----------CPENYHGDG----MVCLPKDPCTDNLGGCPSNSTLCVYQKP 295
GQ C CP +G G CL C G C Y P
Sbjct: 770 ISGQCTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHITGTC--------YCSP 821
Query: 296 GQAFCTCRPGLVSINSNASA 315
G C V I N ++
Sbjct: 822 GWKGARCDQAGVIIVGNLNS 841
Score = 90.5 bits (223), Expect = 2e-17
Identities = 117/466 (25%), Positives = 151/466 (32%), Gaps = 138/466 (29%)
Query: 1943 GRGCHRNCVT--------TTWKPSCCPGHYGSECQ-ACPGGPSSP-CSDRGVCMDG---M 1989
G CH+ C T + C PG+ G+ C+ CP G P C R C +G
Sbjct: 188 GNDCHQRCQCQNGATCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCH 247
Query: 1990 SGSGQCLCRSGFAGTAC-ELCAPGAFGPHC-QACRCTVHGRCDEGLGG------------ 2035
+G+C C SG+ GT C + C G FG +C Q C+C G CD G
Sbjct: 248 HVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGERC 307
Query: 2036 ----------------------------SGSCFCDEGWTGPRCEVQLELQPVCTPPCAPE 2067
SG+C C+ G+ G RCE +L + + C
Sbjct: 308 QDECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKR 367
Query: 2068 AVCRAGNS---------CECSLGYEGDGRVCTVADLCQDGHGG--------CSEHANCSQ 2110
C N+ C C G+ G C + C G G C A+C
Sbjct: 368 CPCHLENTHSCHPMSGECACKPGW--SGLYCN--ETCSPGFYGEACQQICSCQNGADCDS 423
Query: 2111 VGTMVTCTCLPDYEGDGWSCRARNPCTDGHRG-GCSEHANCLSTGLNT---RRCECHAGY 2166
V CTC P ++G S PC G G CS C + + + C C AG+
Sbjct: 424 V--TGKCTCAPGFKGIDCS----TPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGW 477
Query: 2167 VGDGLQCLEESEPP--------VDRCLGQPPPCHSDAMCTDLHFQEKRAGVFHLQATSGP 2218
G+ C +CL D CT R L G
Sbjct: 478 --HGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCA--PGWRGEKCELPCQDGT 533
Query: 2219 YGLNFSEAEAACEAQGAVLASFPQLSAAQQLGFHLCLMGWLANGSTAHPVVFPVADCGNG 2278
YGLN +E A G G CL GW +G V C G
Sbjct: 534 YGLNCAERCDCSHADG----------CHPTTGHCRCLPGW--SGVHCDSV------CAEG 575
Query: 2279 RVGIVSLGARKNLSERWDAYCFRVQDVACRCRNG---FVGDGISTC 2321
RW C + C C+NG DGI C
Sbjct: 576 ---------------RWGPNC----SLPCYCKNGASCSPDDGICEC 602
Score = 85.5 bits (210), Expect = 6e-16
Identities = 73/238 (30%), Positives = 95/238 (39%), Gaps = 41/238 (17%)
Query: 1956 KPSCCPGHYGSECQACPGGPSSPCSDRGVCMDGMS-GSGQCLCRSGFAGTACELCAPGA- 2013
K CCPG Y S P C+D+ C+ G C C G+ GT C G
Sbjct: 91 KSQCCPGFYESGEMCVPH-----CADK--CVHGRCIAPNTCQCEPGWGGTNCSSACDGDH 143
Query: 2014 FGPHCQA-CRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEAVCRA 2072
+GPHC + C+C C+ +G+C C G+ G RCE + E Q C C+
Sbjct: 144 WGPHCTSRCQCKNGALCNPI---TGACHCAAGFRGWRCEDRCE-QGTYGNDCHQRCQCQN 199
Query: 2073 GNSCE-------CSLGYEGDGRVCTVADLCQDGHGG--CSEHANCSQVGTM--VT--CTC 2119
G +C+ C GY G DLC G G C + C G VT C+C
Sbjct: 200 GATCDHVTGECRCPPGYTG----AFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSC 255
Query: 2120 LPDYEGDGW-SCRARNPCTDGHRG-GCSEHANCLSTG---LNTRRCECHAGYVGDGLQ 2172
GW PC +G G CS+ C + G T +C C GY G+ Q
Sbjct: 256 -----PSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGERCQ 308
Score = 84.7 bits (208), Expect = 1e-15
Identities = 80/332 (24%), Positives = 114/332 (34%), Gaps = 73/332 (21%)
Query: 711 CNQTIMEQGCCKGFFGPDCT-QCPGG-FSNPCYGKGNCS--DGIQGN-GACLCFPDYKGI 765
CN C G+ G C C G + C + +CS DG G C C P + G+
Sbjct: 507 CNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGV 566
Query: 766 ACHICSNPNKHGEQCQEDCGCVHG--------LCDNRPGSGGVCQQGTCAPGFSGRFCNE 817
C + G C C C +G +C+ PG G Q C+PGF G C++
Sbjct: 567 HCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQ 626
Query: 818 SMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCS--- 874
+ C + H H+ C G C + F + C+ + G C+
Sbjct: 627 TCPQCVHSSGPCH-HITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPID 685
Query: 875 ENAECVPGSLGT----------------HHCTCHK---------------GWSGDGRVCV 903
+ +C PG +G+ H C CH GW+G
Sbjct: 686 RSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGECKCTPGWTG----LY 741
Query: 904 AIDECELDMRG-------GCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNG 956
C L G C A C ++ +CTC+ GF G C P
Sbjct: 742 CTQRCPLGFYGKDCALICQCQNGADCDHI---SGQCTCRTGFM--GRHCEQKCPSGTYGY 796
Query: 957 GCHGL------ATCRAVGGGQRVCTCPPGFGG 982
GC + +TC + G C C PG+ G
Sbjct: 797 GCRQICDCLNNSTCDHITG---TCYCSPGWKG 825
Score = 84.3 bits (207), Expect = 1e-15
Identities = 74/278 (26%), Positives = 104/278 (37%), Gaps = 38/278 (13%)
Query: 54 TCPSGWLRELPDQITQDCRYEVQLGGSMVSMSGCRRKCRKQVVQKACCPGYWGSRCH-EC 112
+CPSGW+ + Q + R+ +G C Q C PGY G RC EC
Sbjct: 254 SCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNG--GTCDAATGQCHCSPGYTGERCQDEC 311
Query: 113 PGG------AET-PCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDP-NRFGPDCQSVC 164
P G AET C G C +G C+C+ F G C+ P +G C C
Sbjct: 312 PVGTYGVLCAETCQCVNGGKC---YHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRC 368
Query: 165 SCVHGVCNHGPRGDGSCLCFAGYTGPHCDQEL------PVCQEL-RCPQNTQCSAEAPSC 217
C + G C C G++G +C++ CQ++ C C + C
Sbjct: 369 PCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGKC 428
Query: 218 RCLPGYTQQGSECRAPNPCWPSPCSLLAQC-----SVSPKGQAQCHCPENYHGDGMVCLP 272
C PG+ +G +C P P + ++C +V C C +H G+ C
Sbjct: 429 TCAPGF--KGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWH--GVDCSI 484
Query: 273 KDPCTDNLGGCPSNSTLCVYQKPG-----QAFCTCRPG 305
+ C G N T C G CTC PG
Sbjct: 485 R--CPSGTWGFGCNLT-CQCLNGGACNTLDGTCTCAPG 519
Score = 80.5 bits (197), Expect = 2e-14
Identities = 81/322 (25%), Positives = 118/322 (36%), Gaps = 88/322 (27%)
Query: 1949 NCVTTTWKPSCCPGHYGSECQA-CPGGPSS-PCSDRGVCMDGMSGS---GQCLCRSGFAG 2003
+C + T K +C PG G +C CP G CS R C + S G C C++G+ G
Sbjct: 420 DCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHG 479
Query: 2004 TACEL-CAPGAFGPHCQ-ACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQ-------- 2053
C + C G +G C C+C G C+ G+C C GW G +CE+
Sbjct: 480 VDCSIRCPSGTWGFGCNLTCQCLNGGACNTL---DGTCTCAPGWRGEKCELPCQDGTYGL 536
Query: 2054 -----------------------------LELQPVCT-----PPCAPEAVCRAGNS---- 2075
+ VC P C+ C+ G S
Sbjct: 537 NCAERCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPD 596
Query: 2076 ---CECSLGYEGDGRVCTVADLCQDGHGG--CSE------HAN--CSQVGTMVTCTCLPD 2122
CEC+ G+ G T +C G G CS+ H++ C + + C CLP
Sbjct: 597 DGICECAPGFRG----TTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGL--CDCLPG 650
Query: 2123 YEGDGWSCRARNPCTDGHRG-GCSEHANCLSTGLNT---RRCECHAGYVGDGLQCLEESE 2178
+ G C G G C+ C + G R C+C+ G++G C +
Sbjct: 651 FTG----ALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGS--DCSQPCP 704
Query: 2179 PP--VDRCLGQPPPCHSDAMCT 2198
P C+ CH+ A C+
Sbjct: 705 PAHWGPNCI-HTCNCHNGAFCS 725
Score = 80.5 bits (197), Expect = 2e-14
Identities = 73/242 (30%), Positives = 92/242 (38%), Gaps = 51/242 (21%)
Query: 1953 TTWKPSCCPGHYGSEC-QACPG--GPSSPCSDRGVCMDGMSGSGQCLCRSGFAGTAC-EL 2008
TT + C PG YG C Q CP S PC +G C C GF G C E+
Sbjct: 609 TTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHI---------TGLCDCLPGFTGALCNEV 659
Query: 2009 CAPGAFGPHCQA-CRCTVHGRCDEGLGGSGSCFCDEGWTGPRCE---VQLELQPVC--TP 2062
C G FG +C C CT +G C+ SC C GW G C P C T
Sbjct: 660 CPSGRFGKNCAGICTCTNNGTCNP---IDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTC 716
Query: 2063 PCAPEAVCRA-GNSCECSLGYEG-----------DGRVCTVADLCQDGHGGCSEHANCSQ 2110
C A C A C+C+ G+ G G+ C + CQ+G A+C
Sbjct: 717 NCHNGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNG-------ADCDH 769
Query: 2111 VGTMVTCTCLPDYEGDGWSCRARNPCTDGHRG-GCSEHANCLSTGL---NTRRCECHAGY 2166
+ CTC + G C G G GC + +CL+ T C C G+
Sbjct: 770 ISGQ--CTCRTGFMGR----HCEQKCPSGTYGYGCRQICDCLNNSTCDHITGTCYCSPGW 823
Query: 2167 VG 2168
G
Sbjct: 824 KG 825
Score = 80.1 bits (196), Expect = 3e-14
Identities = 89/315 (28%), Positives = 113/315 (35%), Gaps = 61/315 (19%)
Query: 70 DCRYEVQLGGSMVSMS---GCRRKCRKQVVQKAC-CPGYW-GSRCH-ECPGGA-ETPCNG 122
DC LG ++ S GC+ V +C C W G C CP G CN
Sbjct: 438 DCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNL 497
Query: 123 HGTCLDGMDRN---GTCVCQENFRGSACQ-ECQDPNRFGPDCQSVCSCVHGVCNHGPRGD 178
CL+G N GTC C +RG C+ CQD +G +C C C H H
Sbjct: 498 TCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQD-GTYGLNCAERCDCSHADGCHPT--T 554
Query: 179 GSCLCFAGYTGPHCDQELPVCQELR----------CPQNTQCSAEAPSCRCLPGYTQQGS 228
G C C G++G HCD VC E R C CS + C C PG+ +G+
Sbjct: 555 GHCRCLPGWSGVHCDS---VCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGF--RGT 609
Query: 229 ECRAPNPCWPS----PCSLLAQCSVSPKGQAQ-----CHCPENYHGD--GMVCLPKDPCT 277
C+ C P CS V G C C + G VC P
Sbjct: 610 TCQ--RICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVC-PSGRFG 666
Query: 278 DNLGG---CPSNSTLCVYQKPGQAFCTCRPGLVSIN-------SNASAGCFAFCSPFSCD 327
N G C +N T P C C PG + + ++ C C +C
Sbjct: 667 KNCAGICTCTNNGTC----NPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTC---NCH 719
Query: 328 RSATCQVTADGKTSC 342
A C DG+ C
Sbjct: 720 NGAFCS-AYDGECKC 733
Score = 79.0 bits (193), Expect = 6e-14
Identities = 72/276 (26%), Positives = 96/276 (34%), Gaps = 45/276 (16%)
Query: 100 CCPGYWGSRCHECPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPD 159
CCPG++ S C C HG C+ TC C+ + G+ C D + +GP
Sbjct: 94 CCPGFYESG-EMCVPHCADKCV-HGRCI----APNTCQCEPGWGGTNCSSACDGDHWGPH 147
Query: 160 CQSVCSCVHG-VCNHGPRGDGSCLCFAGYTGPHCDQEL-------PVCQELRCPQNTQCS 211
C S C C +G +CN G+C C AG+ G C+ Q +C C
Sbjct: 148 CTSRCQCKNGALCN---PITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCD 204
Query: 212 AEAPSCRCLPGYTQQGSECRAPNPCWPSPCSLLAQC---SVSPKGQAQCHCPENYHGDGM 268
CRC PGYT E P C C V +C CP + G
Sbjct: 205 HVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWM--GT 262
Query: 269 VCLPKDPCTDNLGG------CPSNSTLCVYQKPGQAFCTCRPGLVS--INSNASAGCFAF 320
VC PC + G C ++ GQ C C PG G +
Sbjct: 263 VC--GQPCPEGRFGKNCSQECQCHNGGTCDAATGQ--CHCSPGYTGERCQDECPVGTYGV 318
Query: 321 CSPFSCDRSATCQVTADGKT-----SCVCRESEVGD 351
+ TCQ GK +C+C G+
Sbjct: 319 LC------AETCQCVNGGKCYHVSGACLCEAGFAGE 348
Score = 75.5 bits (184), Expect = 6e-13
Identities = 85/332 (25%), Positives = 109/332 (32%), Gaps = 85/332 (25%)
Query: 91 CRKQVVQKACCPGYWGSRCHEC--PGGAETPCNGHGTCLDGMDRN---GTCVCQENFRGS 145
C + AC PG+ G C+E PG C +C +G D + G C C F+G
Sbjct: 378 CHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGKCTCAPGFKGI 437
Query: 146 ACQECQDPNRFGPDCQSVCSC--------VHGVCN-----HG-------PRG-------- 177
C +G +C S C C V G C HG P G
Sbjct: 438 DCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNL 497
Query: 178 -------------DGSCLCFAGYTGPHCDQELPVCQE----LRCPQNTQCS------AEA 214
DG+C C G+ G C ELP CQ+ L C + CS
Sbjct: 498 TCQCLNGGACNTLDGTCTCAPGWRGEKC--ELP-CQDGTYGLNCAERCDCSHADGCHPTT 554
Query: 215 PSCRCLPGYTQQGSECRAPNPCWPSPCSLLAQC----SVSPKGQAQCHCPENYHGD--GM 268
CRCLPG++ + W CSL C S SP C C + G
Sbjct: 555 GHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSP-DDGICECAPGFRGTTCQR 613
Query: 269 VCLP---KDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPGLVSINSNA-------SAGCF 318
+C P C+ C +S C + C C PG N C
Sbjct: 614 ICSPGFYGHRCSQTCPQCVHSSGPCHHI---TGLCDCLPGFTGALCNEVCPSGRFGKNCA 670
Query: 319 AFCSPFSCDRSATCQVTADGKTSCVCRESEVG 350
C +C + TC SC C +G
Sbjct: 671 GIC---TCTNNGTCNPI---DRSCQCYPGWIG 696
Score = 74.3 bits (181), Expect = 1e-12
Identities = 47/143 (32%), Positives = 59/143 (41%), Gaps = 35/143 (24%)
Query: 1939 PQGLGRGCHRNCVTTTWKPSC---CPGH-------YGSECQACPGGPSSPCSDRGVCMDG 1988
P +G C + C W P+C C H Y EC+ PG C+ R C G
Sbjct: 692 PGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGECKCTPGWTGLYCTQR--CPLG 749
Query: 1989 MSG------------------SGQCLCRSGFAGTACE-LCAPGAFGPHC-QACRCTVHGR 2028
G SGQC CR+GF G CE C G +G C Q C C +
Sbjct: 750 FYGKDCALICQCQNGADCDHISGQCTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLNNST 809
Query: 2029 CDEGLGGSGSCFCDEGWTGPRCE 2051
CD +G+C+C GW G RC+
Sbjct: 810 CDH---ITGTCYCSPGWKGARCD 829
Score = 71.2 bits (173), Expect = 1e-11
Identities = 41/100 (41%), Positives = 52/100 (52%), Gaps = 8/100 (8%)
Query: 1320 CCPGFFGTLC-EPCPGGLGGV-CSGHGQCQ---DRFLGSGECHCHEGFHGTACEV-CELG 1373
C PG+ G C + CP G G C+ QCQ D SG+C C GF G CE C G
Sbjct: 733 CTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQCTCRTGFMGRHCEQKCPSG 792
Query: 1374 RYGPNCTGVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQ 1413
YG C +CDC + + + G +C C+ GW+G RCDQ
Sbjct: 793 TYGYGCRQICDCLNNSTCDHITG--TCYCSPGWKGARCDQ 830
>gi|110347437 latent transforming growth factor beta binding protein 4
isoform c [Homo sapiens]
Length = 1557
Score = 100 bits (248), Expect = 2e-20
Identities = 86/284 (30%), Positives = 114/284 (40%), Gaps = 49/284 (17%)
Query: 1320 CCPGFFGTLCE-----------PCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFH----G 1364
C GF G+ CE PC G G+C D GS C C GF G
Sbjct: 631 CPAGFRGSACEEDVDECAQEPPPC---------GPGRC-DNTAGSFHCACPAGFRSRGPG 680
Query: 1365 TACE-VCELGRYGPNCTGVCDCAHGLCQEGLQGDGSCVCNVGWQ----GLRCDQKITSPQ 1419
C+ V E R P CT +G C E +G CVC +G+Q G C+ + +
Sbjct: 681 APCQDVDECARSPPPCT------YGRC-ENTEGSFQCVCPMGFQPNTAGSECED-VDECE 732
Query: 1420 CPRKCDPNANCVQDSAGASTCACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQ 1479
C P CV C +G+ + C++VD C+ G C PH +CT G
Sbjct: 733 NHLAC-PGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTN-TEGS 790
Query: 1480 RTCTCQDGY---MGDGELCQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGY-SGDGI 1535
C+C GY G C ++N CL C H EC+ T +C+C GY G
Sbjct: 791 FRCSCAPGYRAPSGRPGPCADVNECL-EGDFCFPHGECLNT-DGSFACTCAPGYRPGPRG 848
Query: 1536 RTCELLDPCSKNNGGCSPYATCKSTGDGQRTCTCDTAHTVGDGL 1579
+C +D CS+ + C +T DG C C H G L
Sbjct: 849 ASCLDVDECSEED--LCQSGICTNT-DGSFECICPPGHRAGPDL 889
Score = 77.8 bits (190), Expect = 1e-13
Identities = 74/261 (28%), Positives = 99/261 (37%), Gaps = 52/261 (19%)
Query: 739 PCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQCQE--DCG-----CVHGLC 791
PC G C + G+ C+C Y+ HG CQ+ +C C G C
Sbjct: 572 PC-DLGRC-ENTPGSFLCVCPAGYQAAP---------HGASCQDVDECTQSPGLCGRGAC 620
Query: 792 DNRPGSGGVCQQGTCAPGFSGRFCNESMGDCG----PTGLAQHCHLHARCVSQEGVARCR 847
N PGS + C GF G C E + +C P G RC + G C
Sbjct: 621 KNLPGSF----RCVCPAGFRGSACEEDVDECAQEPPPCG-------PGRCDNTAGSFHCA 669
Query: 848 CLDGFE--GDGFSCTPSNPCSH---PDRGGCSENAECVPGSLGTHHCTCHKGWSGD--GR 900
C GF G G C + C+ P G EN E G+ C C G+ + G
Sbjct: 670 CPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTE------GSFQCVCPMGFQPNTAGS 723
Query: 901 VCVAIDECELDMRGGCHTDALCSYVGPGQSRC-TCKLGFAGDGYQCSPIDPCRAGNGGCH 959
C +DECE + C + PG +C TC G +C+ +D C +G C
Sbjct: 724 ECEDVDECENHL--ACPGQECVN--SPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCG 779
Query: 960 GLATCRAVGGGQRVCTCPPGF 980
C G R C+C PG+
Sbjct: 780 PHGHCTNTEGSFR-CSCAPGY 799
Score = 76.6 bits (187), Expect = 3e-13
Identities = 92/319 (28%), Positives = 115/319 (36%), Gaps = 79/319 (24%)
Query: 1946 CHR--------NCVTTTWKPSC-CPGHY-----GSECQACPGGPSSP-CSDRGVCMDGMS 1990
CHR C T C CP Y G+ CQ SP RG C + +
Sbjct: 566 CHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKN-LP 624
Query: 1991 GSGQCLCRSGFAGTACEL-----------CAPG-----AFGPHCQA------------CR 2022
GS +C+C +GF G+ACE C PG A HC C+
Sbjct: 625 GSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQ 684
Query: 2023 -----------CTVHGRCDEGLGGSGSCFCDEGW----TGPRCEVQLELQPVCTPPCAPE 2067
CT +GRC E GS C C G+ G CE E + P E
Sbjct: 685 DVDECARSPPPCT-YGRC-ENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACP-GQE 741
Query: 2068 AVCRAGN-SCE-CSLGYEGDGRVCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPDY-- 2123
V G+ C C G+ CT D C G C H +C+ C+C P Y
Sbjct: 742 CVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRA 801
Query: 2124 -EGDGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGD--GLQCLEESEPP 2180
G C N C +G C H CL+T + C C GY G CL+
Sbjct: 802 PSGRPGPCADVNECLEG--DFCFPHGECLNTD-GSFACTCAPGYRPGPRGASCLD----- 853
Query: 2181 VDRCLGQPPPCHSDAMCTD 2199
VD C + C S +CT+
Sbjct: 854 VDEC-SEEDLCQS-GICTN 870
Score = 75.5 bits (184), Expect = 6e-13
Identities = 79/285 (27%), Positives = 109/285 (38%), Gaps = 49/285 (17%)
Query: 722 KGFFGPDCT---QCPGGFSNPCYGKGNCSDG-----------IQGNGACLCFPDYK---- 763
+G F C + P G PC C +G G+ AC C P Y+
Sbjct: 788 EGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPR 847
Query: 764 GIACHICSNPNKHGEQCQEDCGCVHGLCDNRPGSGG-VCQQGTCA-PGFSGRFCNESMGD 821
G +C ++C E+ C G+C N GS +C G A P + + +
Sbjct: 848 GASC-------LDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRE 900
Query: 822 CGPTGLAQHCHLHARCVSQEGVARC--RCLDGFE-GDGFSCTPSNPCSHPDRGGC-SENA 877
GP RC + G RC C G+ G +C + C C ++
Sbjct: 901 RGPALCGSQ-----RCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRC 955
Query: 878 ECVPGSLGTHHCT--CHKGWSGD-GRVCVAIDECELDMRGGCHTDALCSYVGPGQSRCTC 934
E PGS + CT C G+ G C +DEC R C A+C + PG +C C
Sbjct: 956 ENTPGS---YRCTPACDPGYQPTPGGGCQDVDECR--NRSFCGAHAVCQNL-PGSFQCLC 1009
Query: 935 KLGFAG--DGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCP 977
G+ G DG C ++ C G C G A C V G +C CP
Sbjct: 1010 DQGYEGARDGRHCVDVNECETLQGVC-GAALCENV-EGSFLCVCP 1052
Score = 71.2 bits (173), Expect = 1e-11
Identities = 81/312 (25%), Positives = 107/312 (34%), Gaps = 90/312 (28%)
Query: 719 GCCKGFFGPDCTQCPGGFSN-----PCYGKGNCS-----------DGIQGNGACLCFPDY 762
G C G CP GF + PC C+ + +G+ C+C +
Sbjct: 657 GRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGF 716
Query: 763 KGIACHICSNPNKHGEQCQEDCGCVHGL------CDNRPGSGGVCQQGTCAPGFS---GR 813
+ PN G +C++ C + L C N PGS Q TC G GR
Sbjct: 717 Q---------PNTAGSECEDVDECENHLACPGQECVNSPGS---FQCRTCPSGHHLHRGR 764
Query: 814 F-----CNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGDGFSCTPSNPCSHP 868
C+ CGP H C + EG RC C G+ P P
Sbjct: 765 CTDVDECSSGAPPCGP---------HGHCTNTEGSFRCSCAPGYRA---------PSGRP 806
Query: 869 DRGGCSENAECVPGSL-----------GTHHCTCHKGW--SGDGRVCVAIDEC---ELDM 912
G C++ EC+ G G+ CTC G+ G C+ +DEC +L
Sbjct: 807 --GPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQ 864
Query: 913 RGGC-HTDALCSYVGPGQSRCTCKLGFAG--DGYQCSPIDPCRAGNGGCHGLATCRAVGG 969
G C +TD G C C G D C +D CR G C G
Sbjct: 865 SGICTNTD--------GSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPG 916
Query: 970 GQR-VCTCPPGF 980
R V C PG+
Sbjct: 917 SYRCVRDCDPGY 928
Score = 70.9 bits (172), Expect = 2e-11
Identities = 81/318 (25%), Positives = 108/318 (33%), Gaps = 87/318 (27%)
Query: 1263 SHAEALREKCVNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRG-CSYTCAKKIQVPDCC 1321
+H ++CVN F+C ++C SG RG C+ P C
Sbjct: 733 NHLACPGQECVNSPGSFQC-----------RTCP--SGHHLHRGRCTDVDECSSGAPPCG 779
Query: 1322 P--------GFFGTLCEP---CPGGLGGVCSGHGQCQ--DRFLGSGECHCHEGFHGTACE 1368
P G F C P P G G C+ +C D GEC +G C
Sbjct: 780 PHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCA 839
Query: 1369 V-CELGRYGPNCTGVCDCAH-GLCQEGL----QGDGSCVCNVGWQG-------------- 1408
G G +C V +C+ LCQ G+ G C+C G +
Sbjct: 840 PGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECR 899
Query: 1409 ---------LRCDQKITSPQCPRKCDPN------------------------ANCVQDSA 1435
RC+ S +C R CDP A +++
Sbjct: 900 ERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTP 959
Query: 1436 GASTC--ACAAGYSGN-GIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMG-- 1490
G+ C AC GY G C +VD C + C HA C + PG C C GY G
Sbjct: 960 GSYRCTPACDPGYQPTPGGGCQDVDECRN-RSFCGAHAVCQNL-PGSFQCLCDQGYEGAR 1017
Query: 1491 DGELCQEINSCLIHHGGC 1508
DG C ++N C G C
Sbjct: 1018 DGRHCVDVNECETLQGVC 1035
Score = 65.1 bits (157), Expect = 9e-10
Identities = 74/268 (27%), Positives = 100/268 (37%), Gaps = 41/268 (15%)
Query: 100 CCPGYW----GSRCHECPGGAETP--CNGHGTCLDGMDRNGTCVCQENFRGSACQE---- 149
C GY G+ C + ++P C G G C + + + CVC FRGSAC+E
Sbjct: 589 CPAGYQAAPHGASCQDVDECTQSPGLC-GRGACKN-LPGSFRCVCPAGFRGSACEEDVDE 646
Query: 150 -CQDPNRFGPD-CQSVCSCVHGVCNHGPRGDG-SCLCFAGYTGPHCDQELPVCQELRCPQ 206
Q+P GP C + H C G R G C C + P C RC +
Sbjct: 647 CAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPC---QDVDECARSPPPCTYGRC-E 702
Query: 207 NTQCSAEAPSCRCLPGY--TQQGSECRAPNPCWPSPCSLLAQCSVSPKGQAQCH-CPENY 263
NT+ S + C C G+ GSEC + C +C SP G QC CP +
Sbjct: 703 NTEGSFQ---CVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSP-GSFQCRTCPSGH 758
Query: 264 HGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPGLVSINSNASAGCFAFCSP 323
H C D C+ C + G C+C PG A +G C+
Sbjct: 759 HLHRGRCTDVDECSSGAPPCGPHGHCT--NTEGSFRCSCAPGY-----RAPSGRPGPCAD 811
Query: 324 FS-------CDRSATCQVTADGKTSCVC 344
+ C C + DG +C C
Sbjct: 812 VNECLEGDFCFPHGEC-LNTDGSFACTC 838
Score = 54.3 bits (129), Expect = 2e-06
Identities = 64/221 (28%), Positives = 73/221 (33%), Gaps = 35/221 (15%)
Query: 783 DCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMG-DCGPTGL----AQHCH----- 832
+ G G+C P VC G C SG C G P G C
Sbjct: 474 ESGPSSGMCQRNPQ---VCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPP 530
Query: 833 -LHARCVSQEGVARCRCLDGFEGD--GFSCTPSNPCSHP----DRGGCSENAECVPGSLG 885
RC + G RC C GF C + C D G C E PGS
Sbjct: 531 CAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRC----ENTPGSF- 585
Query: 886 THHCTCHKGWSG--DGRVCVAIDECELDMRGGCHTDALCSYVGPGQSRCTCKLGFAGDGY 943
C C G+ G C +DEC G C A C + PG RC C GF G
Sbjct: 586 --LCVCPAGYQAAPHGASCQDVDECT-QSPGLCGRGA-CKNL-PGSFRCVCPAGFRGSAC 640
Query: 944 QCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGFGGDG 984
+ +D C C G C G C CP GF G
Sbjct: 641 E-EDVDECAQEPPPC-GPGRCDNTAGSFH-CACPAGFRSRG 678
Score = 54.3 bits (129), Expect = 2e-06
Identities = 64/257 (24%), Positives = 83/257 (32%), Gaps = 72/257 (28%)
Query: 1945 GCHRNCVTT--TWKPSCCPGHYGSECQACPGGPSSPCSDRGVCMDG--MSGSGQCLCRSG 2000
G H +C T +++ SC PG+ P G PC+D C++G G+CL G
Sbjct: 779 GPHGHCTNTEGSFRCSCAPGY------RAPSGRPGPCADVNECLEGDFCFPHGECLNTDG 832
Query: 2001 -FAGTACELCAPGAFGPHC-QACRCTVHGRCDEGL----GGSGSCFCDEGW-TGPRCEVQ 2053
FA T PG G C C+ C G+ GS C C G GP
Sbjct: 833 SFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASC 892
Query: 2054 LELQPV---------------------CTPPC------APEAVCRAGNSCE--------- 2077
L++ C C PE C + C+
Sbjct: 893 LDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGA 952
Query: 2078 ---------------CSLGYEGD-GRVCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLP 2121
C GY+ G C D C++ C HA C + C C
Sbjct: 953 QRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRN-RSFCGAHAVCQNLPGSFQCLCDQ 1011
Query: 2122 DYEG--DGWSCRARNPC 2136
YEG DG C N C
Sbjct: 1012 GYEGARDGRHCVDVNEC 1028
Score = 52.8 bits (125), Expect = 4e-06
Identities = 45/154 (29%), Positives = 66/154 (42%), Gaps = 13/154 (8%)
Query: 1421 PRKCDPNANCVQDSAGASTCACAAGY--SGNGIFCSEVDPCAHGHGGCSPHANCTKVAPG 1478
P+ C P C+ +G TCAC +G+ S G C +VD C C+P C +PG
Sbjct: 486 PQVCGPG-RCISRPSGY-TCACDSGFRLSPQGTRCIDVDECRRVPPPCAP-GRCEN-SPG 541
Query: 1479 QRTCTCQDGYMGDGEL--CQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGY-SGDGI 1535
C C G+ C +++ C C + C T P C C GY +
Sbjct: 542 SFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDL-GRCENT-PGSFLCVCPAGYQAAPHG 599
Query: 1536 RTCELLDPCSKNNGGCSPYATCKSTGDGQRTCTC 1569
+C+ +D C+++ G C A CK+ G C C
Sbjct: 600 ASCQDVDECTQSPGLCGRGA-CKNL-PGSFRCVC 631
Score = 45.8 bits (107), Expect = 5e-04
Identities = 67/266 (25%), Positives = 91/266 (34%), Gaps = 57/266 (21%)
Query: 654 CSEEQHKIVAGSCVDCQALNTSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKGCASYCNQ 713
C E G C++ TC P Y P G + L S +
Sbjct: 815 CLEGDFCFPHGECLNTDGSFACTCAPG------------YRPGPRGASCLDVDECS--EE 860
Query: 714 TIMEQGCCKGFFGP-DCTQCPGGFSNP----------CYGKGNCSDGIQ------GNGAC 756
+ + G C G +C PG + P C +G G Q G+ C
Sbjct: 861 DLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRC 920
Query: 757 L--CFPDYKGIACHICSNPNKHGEQCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFS--- 811
+ C P Y C + ++ E E CG C+N PGS C PG+
Sbjct: 921 VRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQR--CENTPGSYRCTP--ACDPGYQPTP 976
Query: 812 GRFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEG--DGFSCTPSNPCSHPD 869
G C + + +C C HA C + G +C C G+EG DG C N C
Sbjct: 977 GGGCQD-VDECRNRSF---CGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNEC-ETL 1031
Query: 870 RGGCS----ENAECVPGSLGTHHCTC 891
+G C EN E G+ C C
Sbjct: 1032 QGVCGAALCENVE------GSFLCVC 1051
Score = 39.7 bits (91), Expect = 0.039
Identities = 33/117 (28%), Positives = 45/117 (38%), Gaps = 26/117 (22%)
Query: 1442 CAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINSC 1501
C G+ C +VD CA G G C H C G TC C DG++ D +SC
Sbjct: 277 CPTGFERVNGSCEDVDECATG-GRCQ-HGECANTRGGY-TCVCPDGFLLDSSR----SSC 329
Query: 1502 LIHH---------------GGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLDP 1543
+ H GGC + + +Q+ C R G + R C+L P
Sbjct: 330 ISQHVISEAKGPCFRVLRDGGCSL--PILRNITKQICCCSRVGKAWG--RGCQLCPP 382
Score = 37.0 bits (84), Expect = 0.25
Identities = 56/227 (24%), Positives = 79/227 (34%), Gaps = 41/227 (18%)
Query: 749 GIQGNGACLCFPDYKGIACHICSNPNKHGEQCQEDCGCVHGLCDNRPGSGGVCQQGTCAP 808
G G+G C+ D A C N QE C C G G C+ C
Sbjct: 1107 GPVGSGRRECYFDTA--APDACDNILARNVTWQECC------CTVGEGWGSGCRIQQCPG 1158
Query: 809 GFSGRF---CNESMGDCGPTGL------AQHCHLHARCVSQEGVA-------RCRCLDGF 852
+ + C G P+G C L V + GV C C +G+
Sbjct: 1159 TETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGY 1218
Query: 853 --EGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDG--RVCVAIDEC 908
C ++ C+ D E CV ++G++HCTC DG R CV+ +
Sbjct: 1219 YYHTQRLECIDNDECA--DEEPACEGGRCV-NTVGSYHCTCEPPLVLDGSQRRCVSNESQ 1275
Query: 909 ELDMRGG-----CHTDALCSYVGPGQ----SRCTCKLGFAGDGYQCS 946
LD G D +CS+ + + C C G A G C+
Sbjct: 1276 SLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYGEAW-GMDCA 1321
Score = 36.6 bits (83), Expect = 0.33
Identities = 27/90 (30%), Positives = 35/90 (38%), Gaps = 16/90 (17%)
Query: 1939 PQGLGRGCHRNCVTTTWKPSCCPGHYGSECQACPGG--PSSP----------CSDRGVCM 1986
P G C + P+C P + S PGG P P C + GVC+
Sbjct: 38 PVVCGLRCVHGPTGSRCTPTCAPRNATSVDSGAPGGAAPGGPGFRAFLCPLICHNGGVCV 97
Query: 1987 DGMSGSGQCLCRSGFAGTACELCAPGAFGP 2016
+CLC FAG C+L + GA P
Sbjct: 98 K----PDRCLCPPDFAGKFCQLHSSGARPP 123
Score = 36.6 bits (83), Expect = 0.33
Identities = 48/169 (28%), Positives = 68/169 (40%), Gaps = 20/169 (11%)
Query: 855 DGFS-CTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGRVCVAIDECELDMR 913
DG+S + C RGG E A +PG L T C G G + + +C+L
Sbjct: 211 DGYSDASGFGYCFRELRGG--ECASPLPG-LRTQEVCCR----GAG-LAWGVHDCQLCSE 262
Query: 914 GGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRV 973
+++ + + GP C GF C +D C G HG C GG
Sbjct: 263 RLGNSERVSAPDGP------CPTGFERVNGSCEDVDECATGGRCQHG--ECANTRGGY-T 313
Query: 974 CTCPPGFGGDGFSCYGDIFRELEANAHFSIFYQWLKSAGITLPADRRVT 1022
C CP GF D S I + + + A F + L+ G +LP R +T
Sbjct: 314 CVCPDGFLLDS-SRSSCISQHVISEAKGPCF-RVLRDGGCSLPILRNIT 360
Score = 36.2 bits (82), Expect = 0.43
Identities = 26/92 (28%), Positives = 38/92 (41%), Gaps = 9/92 (9%)
Query: 778 EQCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFS---GRFCNESMGDCGPTGLAQHCHLH 834
E+C GC +G C P G C+ C G+ R + +C A ++
Sbjct: 1468 EECGILDGCTNGRCVRVP-EGFTCR---CFDGYRLDMTRMACVDINECDEAEAASPLCVN 1523
Query: 835 ARCVSQEGVARCRCLDGF--EGDGFSCTPSNP 864
ARC++ +G RC C GF C P+ P
Sbjct: 1524 ARCLNTDGSFRCICRPGFAPTHQPHHCAPARP 1555
Score = 35.0 bits (79), Expect = 0.95
Identities = 44/169 (26%), Positives = 58/169 (34%), Gaps = 27/169 (15%)
Query: 753 NGACLCFPDYKGIACHICSNPNKHGEQCQEDCGCVHG-----LCDNRPGSGG--VCQQGT 805
+G CF + +G C + E C G G LC R G+ G
Sbjct: 217 SGFGYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGP 276
Query: 806 CAPGFS--GRFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGF--EGDGFSCTP 861
C GF C E + +C G QH C + G C C DGF + SC
Sbjct: 277 CPTGFERVNGSC-EDVDECATGGRCQH----GECANTRGGYTCVCPDGFLLDSSRSSCIS 331
Query: 862 SN-------PCSHPDR-GGCSENAECVPGSLGTHHCTCHKGWSGDGRVC 902
+ PC R GGCS + ++ C C + GR C
Sbjct: 332 QHVISEAKGPCFRVLRDGGCSLP---ILRNITKQICCCSRVGKAWGRGC 377
Score = 34.3 bits (77), Expect = 1.6
Identities = 28/91 (30%), Positives = 35/91 (38%), Gaps = 6/91 (6%)
Query: 896 SGDGRVCVAIDECELDMRGGCHTDALCSYVGPGQSRCTCKLGFA--GDGYQCSPIDPCRA 953
SGD + +DEC+L C + +C PG S C C G+ +C D C
Sbjct: 1178 SGDLSLRRDVDECQLFRDQVCKS-GVCVNTAPGYS-CYCSNGYYYHTQRLECIDNDECAD 1235
Query: 954 GNGGCHGLATCRAVGGGQRVCTCPPGFGGDG 984
C G VG CTC P DG
Sbjct: 1236 EEPACEGGRCVNTVGSYH--CTCEPPLVLDG 1264
Score = 32.7 bits (73), Expect = 4.7
Identities = 18/53 (33%), Positives = 21/53 (39%), Gaps = 5/53 (9%)
Query: 257 CHCPENY--HGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPGLV 307
C+C Y H + C+ D C D C CV G CTC P LV
Sbjct: 1212 CYCSNGYYYHTQRLECIDNDECADEEPACEGGR--CV-NTVGSYHCTCEPPLV 1261
Score = 32.0 bits (71), Expect = 8.1
Identities = 28/84 (33%), Positives = 36/84 (42%), Gaps = 8/84 (9%)
Query: 872 GCSENAECVPGSLGTHHCTCHKGWSGD--GRVCVAIDEC-ELDMRGGCHTDALCSYVGPG 928
GC+ N CV G C C G+ D CV I+EC E + +A C G
Sbjct: 1475 GCT-NGRCVRVPEG-FTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTD-G 1531
Query: 929 QSRCTCKLGFA--GDGYQCSPIDP 950
RC C+ GFA + C+P P
Sbjct: 1532 SFRCICRPGFAPTHQPHHCAPARP 1555
>gi|110347412 latent transforming growth factor beta binding protein 4
isoform b [Homo sapiens]
Length = 1587
Score = 100 bits (248), Expect = 2e-20
Identities = 86/284 (30%), Positives = 114/284 (40%), Gaps = 49/284 (17%)
Query: 1320 CCPGFFGTLCE-----------PCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFH----G 1364
C GF G+ CE PC G G+C D GS C C GF G
Sbjct: 661 CPAGFRGSACEEDVDECAQEPPPC---------GPGRC-DNTAGSFHCACPAGFRSRGPG 710
Query: 1365 TACE-VCELGRYGPNCTGVCDCAHGLCQEGLQGDGSCVCNVGWQ----GLRCDQKITSPQ 1419
C+ V E R P CT +G C E +G CVC +G+Q G C+ + +
Sbjct: 711 APCQDVDECARSPPPCT------YGRC-ENTEGSFQCVCPMGFQPNTAGSECED-VDECE 762
Query: 1420 CPRKCDPNANCVQDSAGASTCACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQ 1479
C P CV C +G+ + C++VD C+ G C PH +CT G
Sbjct: 763 NHLAC-PGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTN-TEGS 820
Query: 1480 RTCTCQDGY---MGDGELCQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGY-SGDGI 1535
C+C GY G C ++N CL C H EC+ T +C+C GY G
Sbjct: 821 FRCSCAPGYRAPSGRPGPCADVNECL-EGDFCFPHGECLNT-DGSFACTCAPGYRPGPRG 878
Query: 1536 RTCELLDPCSKNNGGCSPYATCKSTGDGQRTCTCDTAHTVGDGL 1579
+C +D CS+ + C +T DG C C H G L
Sbjct: 879 ASCLDVDECSEED--LCQSGICTNT-DGSFECICPPGHRAGPDL 919
Score = 77.8 bits (190), Expect = 1e-13
Identities = 74/261 (28%), Positives = 99/261 (37%), Gaps = 52/261 (19%)
Query: 739 PCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQCQE--DCG-----CVHGLC 791
PC G C + G+ C+C Y+ HG CQ+ +C C G C
Sbjct: 602 PC-DLGRC-ENTPGSFLCVCPAGYQAAP---------HGASCQDVDECTQSPGLCGRGAC 650
Query: 792 DNRPGSGGVCQQGTCAPGFSGRFCNESMGDCG----PTGLAQHCHLHARCVSQEGVARCR 847
N PGS + C GF G C E + +C P G RC + G C
Sbjct: 651 KNLPGSF----RCVCPAGFRGSACEEDVDECAQEPPPCG-------PGRCDNTAGSFHCA 699
Query: 848 CLDGFE--GDGFSCTPSNPCSH---PDRGGCSENAECVPGSLGTHHCTCHKGWSGD--GR 900
C GF G G C + C+ P G EN E G+ C C G+ + G
Sbjct: 700 CPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTE------GSFQCVCPMGFQPNTAGS 753
Query: 901 VCVAIDECELDMRGGCHTDALCSYVGPGQSRC-TCKLGFAGDGYQCSPIDPCRAGNGGCH 959
C +DECE + C + PG +C TC G +C+ +D C +G C
Sbjct: 754 ECEDVDECENHL--ACPGQECVN--SPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCG 809
Query: 960 GLATCRAVGGGQRVCTCPPGF 980
C G R C+C PG+
Sbjct: 810 PHGHCTNTEGSFR-CSCAPGY 829
Score = 76.6 bits (187), Expect = 3e-13
Identities = 92/319 (28%), Positives = 115/319 (36%), Gaps = 79/319 (24%)
Query: 1946 CHR--------NCVTTTWKPSC-CPGHY-----GSECQACPGGPSSP-CSDRGVCMDGMS 1990
CHR C T C CP Y G+ CQ SP RG C + +
Sbjct: 596 CHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKN-LP 654
Query: 1991 GSGQCLCRSGFAGTACEL-----------CAPG-----AFGPHCQA------------CR 2022
GS +C+C +GF G+ACE C PG A HC C+
Sbjct: 655 GSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQ 714
Query: 2023 -----------CTVHGRCDEGLGGSGSCFCDEGW----TGPRCEVQLELQPVCTPPCAPE 2067
CT +GRC E GS C C G+ G CE E + P E
Sbjct: 715 DVDECARSPPPCT-YGRC-ENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACP-GQE 771
Query: 2068 AVCRAGN-SCE-CSLGYEGDGRVCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPDY-- 2123
V G+ C C G+ CT D C G C H +C+ C+C P Y
Sbjct: 772 CVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRA 831
Query: 2124 -EGDGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGD--GLQCLEESEPP 2180
G C N C +G C H CL+T + C C GY G CL+
Sbjct: 832 PSGRPGPCADVNECLEG--DFCFPHGECLNTD-GSFACTCAPGYRPGPRGASCLD----- 883
Query: 2181 VDRCLGQPPPCHSDAMCTD 2199
VD C + C S +CT+
Sbjct: 884 VDEC-SEEDLCQS-GICTN 900
Score = 75.5 bits (184), Expect = 6e-13
Identities = 79/285 (27%), Positives = 109/285 (38%), Gaps = 49/285 (17%)
Query: 722 KGFFGPDCT---QCPGGFSNPCYGKGNCSDG-----------IQGNGACLCFPDYK---- 763
+G F C + P G PC C +G G+ AC C P Y+
Sbjct: 818 EGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPR 877
Query: 764 GIACHICSNPNKHGEQCQEDCGCVHGLCDNRPGSGG-VCQQGTCA-PGFSGRFCNESMGD 821
G +C ++C E+ C G+C N GS +C G A P + + +
Sbjct: 878 GASC-------LDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRE 930
Query: 822 CGPTGLAQHCHLHARCVSQEGVARC--RCLDGFE-GDGFSCTPSNPCSHPDRGGC-SENA 877
GP RC + G RC C G+ G +C + C C ++
Sbjct: 931 RGPALCGSQ-----RCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRC 985
Query: 878 ECVPGSLGTHHCT--CHKGWSGD-GRVCVAIDECELDMRGGCHTDALCSYVGPGQSRCTC 934
E PGS + CT C G+ G C +DEC R C A+C + PG +C C
Sbjct: 986 ENTPGS---YRCTPACDPGYQPTPGGGCQDVDECR--NRSFCGAHAVCQNL-PGSFQCLC 1039
Query: 935 KLGFAG--DGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCP 977
G+ G DG C ++ C G C G A C V G +C CP
Sbjct: 1040 DQGYEGARDGRHCVDVNECETLQGVC-GAALCENV-EGSFLCVCP 1082
Score = 71.2 bits (173), Expect = 1e-11
Identities = 81/312 (25%), Positives = 107/312 (34%), Gaps = 90/312 (28%)
Query: 719 GCCKGFFGPDCTQCPGGFSN-----PCYGKGNCS-----------DGIQGNGACLCFPDY 762
G C G CP GF + PC C+ + +G+ C+C +
Sbjct: 687 GRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGF 746
Query: 763 KGIACHICSNPNKHGEQCQEDCGCVHGL------CDNRPGSGGVCQQGTCAPGFS---GR 813
+ PN G +C++ C + L C N PGS Q TC G GR
Sbjct: 747 Q---------PNTAGSECEDVDECENHLACPGQECVNSPGS---FQCRTCPSGHHLHRGR 794
Query: 814 F-----CNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGDGFSCTPSNPCSHP 868
C+ CGP H C + EG RC C G+ P P
Sbjct: 795 CTDVDECSSGAPPCGP---------HGHCTNTEGSFRCSCAPGYRA---------PSGRP 836
Query: 869 DRGGCSENAECVPGSL-----------GTHHCTCHKGW--SGDGRVCVAIDEC---ELDM 912
G C++ EC+ G G+ CTC G+ G C+ +DEC +L
Sbjct: 837 --GPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQ 894
Query: 913 RGGC-HTDALCSYVGPGQSRCTCKLGFAG--DGYQCSPIDPCRAGNGGCHGLATCRAVGG 969
G C +TD G C C G D C +D CR G C G
Sbjct: 895 SGICTNTD--------GSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPG 946
Query: 970 GQR-VCTCPPGF 980
R V C PG+
Sbjct: 947 SYRCVRDCDPGY 958
Score = 70.9 bits (172), Expect = 2e-11
Identities = 81/318 (25%), Positives = 108/318 (33%), Gaps = 87/318 (27%)
Query: 1263 SHAEALREKCVNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRG-CSYTCAKKIQVPDCC 1321
+H ++CVN F+C ++C SG RG C+ P C
Sbjct: 763 NHLACPGQECVNSPGSFQC-----------RTCP--SGHHLHRGRCTDVDECSSGAPPCG 809
Query: 1322 P--------GFFGTLCEP---CPGGLGGVCSGHGQCQ--DRFLGSGECHCHEGFHGTACE 1368
P G F C P P G G C+ +C D GEC +G C
Sbjct: 810 PHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCA 869
Query: 1369 V-CELGRYGPNCTGVCDCAH-GLCQEGL----QGDGSCVCNVGWQG-------------- 1408
G G +C V +C+ LCQ G+ G C+C G +
Sbjct: 870 PGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECR 929
Query: 1409 ---------LRCDQKITSPQCPRKCDPN------------------------ANCVQDSA 1435
RC+ S +C R CDP A +++
Sbjct: 930 ERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTP 989
Query: 1436 GASTC--ACAAGYSGN-GIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMG-- 1490
G+ C AC GY G C +VD C + C HA C + PG C C GY G
Sbjct: 990 GSYRCTPACDPGYQPTPGGGCQDVDECRN-RSFCGAHAVCQNL-PGSFQCLCDQGYEGAR 1047
Query: 1491 DGELCQEINSCLIHHGGC 1508
DG C ++N C G C
Sbjct: 1048 DGRHCVDVNECETLQGVC 1065
Score = 65.1 bits (157), Expect = 9e-10
Identities = 74/268 (27%), Positives = 100/268 (37%), Gaps = 41/268 (15%)
Query: 100 CCPGYW----GSRCHECPGGAETP--CNGHGTCLDGMDRNGTCVCQENFRGSACQE---- 149
C GY G+ C + ++P C G G C + + + CVC FRGSAC+E
Sbjct: 619 CPAGYQAAPHGASCQDVDECTQSPGLC-GRGACKN-LPGSFRCVCPAGFRGSACEEDVDE 676
Query: 150 -CQDPNRFGPD-CQSVCSCVHGVCNHGPRGDG-SCLCFAGYTGPHCDQELPVCQELRCPQ 206
Q+P GP C + H C G R G C C + P C RC +
Sbjct: 677 CAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPC---QDVDECARSPPPCTYGRC-E 732
Query: 207 NTQCSAEAPSCRCLPGY--TQQGSECRAPNPCWPSPCSLLAQCSVSPKGQAQCH-CPENY 263
NT+ S + C C G+ GSEC + C +C SP G QC CP +
Sbjct: 733 NTEGSFQ---CVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSP-GSFQCRTCPSGH 788
Query: 264 HGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPGLVSINSNASAGCFAFCSP 323
H C D C+ C + G C+C PG A +G C+
Sbjct: 789 HLHRGRCTDVDECSSGAPPCGPHGHCT--NTEGSFRCSCAPGY-----RAPSGRPGPCAD 841
Query: 324 FS-------CDRSATCQVTADGKTSCVC 344
+ C C + DG +C C
Sbjct: 842 VNECLEGDFCFPHGEC-LNTDGSFACTC 868
Score = 54.3 bits (129), Expect = 2e-06
Identities = 64/221 (28%), Positives = 73/221 (33%), Gaps = 35/221 (15%)
Query: 783 DCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMG-DCGPTGL----AQHCH----- 832
+ G G+C P VC G C SG C G P G C
Sbjct: 504 ESGPSSGMCQRNPQ---VCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPP 560
Query: 833 -LHARCVSQEGVARCRCLDGFEGD--GFSCTPSNPCSHP----DRGGCSENAECVPGSLG 885
RC + G RC C GF C + C D G C E PGS
Sbjct: 561 CAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRC----ENTPGSF- 615
Query: 886 THHCTCHKGWSG--DGRVCVAIDECELDMRGGCHTDALCSYVGPGQSRCTCKLGFAGDGY 943
C C G+ G C +DEC G C A C + PG RC C GF G
Sbjct: 616 --LCVCPAGYQAAPHGASCQDVDECT-QSPGLCGRGA-CKNL-PGSFRCVCPAGFRGSAC 670
Query: 944 QCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGFGGDG 984
+ +D C C G C G C CP GF G
Sbjct: 671 E-EDVDECAQEPPPC-GPGRCDNTAGSFH-CACPAGFRSRG 708
Score = 54.3 bits (129), Expect = 2e-06
Identities = 64/257 (24%), Positives = 83/257 (32%), Gaps = 72/257 (28%)
Query: 1945 GCHRNCVTT--TWKPSCCPGHYGSECQACPGGPSSPCSDRGVCMDG--MSGSGQCLCRSG 2000
G H +C T +++ SC PG+ P G PC+D C++G G+CL G
Sbjct: 809 GPHGHCTNTEGSFRCSCAPGY------RAPSGRPGPCADVNECLEGDFCFPHGECLNTDG 862
Query: 2001 -FAGTACELCAPGAFGPHC-QACRCTVHGRCDEGL----GGSGSCFCDEGW-TGPRCEVQ 2053
FA T PG G C C+ C G+ GS C C G GP
Sbjct: 863 SFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASC 922
Query: 2054 LELQPV---------------------CTPPC------APEAVCRAGNSCE--------- 2077
L++ C C PE C + C+
Sbjct: 923 LDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGA 982
Query: 2078 ---------------CSLGYEGD-GRVCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLP 2121
C GY+ G C D C++ C HA C + C C
Sbjct: 983 QRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRN-RSFCGAHAVCQNLPGSFQCLCDQ 1041
Query: 2122 DYEG--DGWSCRARNPC 2136
YEG DG C N C
Sbjct: 1042 GYEGARDGRHCVDVNEC 1058
Score = 52.8 bits (125), Expect = 4e-06
Identities = 45/154 (29%), Positives = 66/154 (42%), Gaps = 13/154 (8%)
Query: 1421 PRKCDPNANCVQDSAGASTCACAAGY--SGNGIFCSEVDPCAHGHGGCSPHANCTKVAPG 1478
P+ C P C+ +G TCAC +G+ S G C +VD C C+P C +PG
Sbjct: 516 PQVCGPG-RCISRPSGY-TCACDSGFRLSPQGTRCIDVDECRRVPPPCAP-GRCEN-SPG 571
Query: 1479 QRTCTCQDGYMGDGEL--CQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGY-SGDGI 1535
C C G+ C +++ C C + C T P C C GY +
Sbjct: 572 SFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDL-GRCENT-PGSFLCVCPAGYQAAPHG 629
Query: 1536 RTCELLDPCSKNNGGCSPYATCKSTGDGQRTCTC 1569
+C+ +D C+++ G C A CK+ G C C
Sbjct: 630 ASCQDVDECTQSPGLCGRGA-CKNL-PGSFRCVC 661
Score = 45.8 bits (107), Expect = 5e-04
Identities = 67/266 (25%), Positives = 91/266 (34%), Gaps = 57/266 (21%)
Query: 654 CSEEQHKIVAGSCVDCQALNTSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKGCASYCNQ 713
C E G C++ TC P Y P G + L S +
Sbjct: 845 CLEGDFCFPHGECLNTDGSFACTCAPG------------YRPGPRGASCLDVDECS--EE 890
Query: 714 TIMEQGCCKGFFGP-DCTQCPGGFSNP----------CYGKGNCSDGIQ------GNGAC 756
+ + G C G +C PG + P C +G G Q G+ C
Sbjct: 891 DLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRC 950
Query: 757 L--CFPDYKGIACHICSNPNKHGEQCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFS--- 811
+ C P Y C + ++ E E CG C+N PGS C PG+
Sbjct: 951 VRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQR--CENTPGSYRCTP--ACDPGYQPTP 1006
Query: 812 GRFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEG--DGFSCTPSNPCSHPD 869
G C + + +C C HA C + G +C C G+EG DG C N C
Sbjct: 1007 GGGCQD-VDECRNRSF---CGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNEC-ETL 1061
Query: 870 RGGCS----ENAECVPGSLGTHHCTC 891
+G C EN E G+ C C
Sbjct: 1062 QGVCGAALCENVE------GSFLCVC 1081
Score = 39.7 bits (91), Expect = 0.039
Identities = 33/117 (28%), Positives = 45/117 (38%), Gaps = 26/117 (22%)
Query: 1442 CAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINSC 1501
C G+ C +VD CA G G C H C G TC C DG++ D +SC
Sbjct: 307 CPTGFERVNGSCEDVDECATG-GRCQ-HGECANTRGGY-TCVCPDGFLLDSSR----SSC 359
Query: 1502 LIHH---------------GGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLDP 1543
+ H GGC + + +Q+ C R G + R C+L P
Sbjct: 360 ISQHVISEAKGPCFRVLRDGGCSL--PILRNITKQICCCSRVGKAWG--RGCQLCPP 412
Score = 37.0 bits (84), Expect = 0.25
Identities = 56/227 (24%), Positives = 79/227 (34%), Gaps = 41/227 (18%)
Query: 749 GIQGNGACLCFPDYKGIACHICSNPNKHGEQCQEDCGCVHGLCDNRPGSGGVCQQGTCAP 808
G G+G C+ D A C N QE C C G G C+ C
Sbjct: 1137 GPVGSGRRECYFDTA--APDACDNILARNVTWQECC------CTVGEGWGSGCRIQQCPG 1188
Query: 809 GFSGRF---CNESMGDCGPTGL------AQHCHLHARCVSQEGVA-------RCRCLDGF 852
+ + C G P+G C L V + GV C C +G+
Sbjct: 1189 TETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGY 1248
Query: 853 --EGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDG--RVCVAIDEC 908
C ++ C+ D E CV ++G++HCTC DG R CV+ +
Sbjct: 1249 YYHTQRLECIDNDECA--DEEPACEGGRCV-NTVGSYHCTCEPPLVLDGSQRRCVSNESQ 1305
Query: 909 ELDMRGG-----CHTDALCSYVGPGQ----SRCTCKLGFAGDGYQCS 946
LD G D +CS+ + + C C G A G C+
Sbjct: 1306 SLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYGEAW-GMDCA 1351
Score = 36.6 bits (83), Expect = 0.33
Identities = 48/169 (28%), Positives = 68/169 (40%), Gaps = 20/169 (11%)
Query: 855 DGFS-CTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGRVCVAIDECELDMR 913
DG+S + C RGG E A +PG L T C G G + + +C+L
Sbjct: 241 DGYSDASGFGYCFRELRGG--ECASPLPG-LRTQEVCCR----GAG-LAWGVHDCQLCSE 292
Query: 914 GGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRV 973
+++ + + GP C GF C +D C G HG C GG
Sbjct: 293 RLGNSERVSAPDGP------CPTGFERVNGSCEDVDECATGGRCQHG--ECANTRGGY-T 343
Query: 974 CTCPPGFGGDGFSCYGDIFRELEANAHFSIFYQWLKSAGITLPADRRVT 1022
C CP GF D S I + + + A F + L+ G +LP R +T
Sbjct: 344 CVCPDGFLLDS-SRSSCISQHVISEAKGPCF-RVLRDGGCSLPILRNIT 390
Score = 36.2 bits (82), Expect = 0.43
Identities = 26/92 (28%), Positives = 38/92 (41%), Gaps = 9/92 (9%)
Query: 778 EQCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFS---GRFCNESMGDCGPTGLAQHCHLH 834
E+C GC +G C P G C+ C G+ R + +C A ++
Sbjct: 1498 EECGILDGCTNGRCVRVP-EGFTCR---CFDGYRLDMTRMACVDINECDEAEAASPLCVN 1553
Query: 835 ARCVSQEGVARCRCLDGF--EGDGFSCTPSNP 864
ARC++ +G RC C GF C P+ P
Sbjct: 1554 ARCLNTDGSFRCICRPGFAPTHQPHHCAPARP 1585
Score = 35.0 bits (79), Expect = 0.95
Identities = 44/169 (26%), Positives = 58/169 (34%), Gaps = 27/169 (15%)
Query: 753 NGACLCFPDYKGIACHICSNPNKHGEQCQEDCGCVHG-----LCDNRPGSGG--VCQQGT 805
+G CF + +G C + E C G G LC R G+ G
Sbjct: 247 SGFGYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGP 306
Query: 806 CAPGFS--GRFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGF--EGDGFSCTP 861
C GF C E + +C G QH C + G C C DGF + SC
Sbjct: 307 CPTGFERVNGSC-EDVDECATGGRCQH----GECANTRGGYTCVCPDGFLLDSSRSSCIS 361
Query: 862 SN-------PCSHPDR-GGCSENAECVPGSLGTHHCTCHKGWSGDGRVC 902
+ PC R GGCS + ++ C C + GR C
Sbjct: 362 QHVISEAKGPCFRVLRDGGCSLP---ILRNITKQICCCSRVGKAWGRGC 407
Score = 34.3 bits (77), Expect = 1.6
Identities = 28/91 (30%), Positives = 35/91 (38%), Gaps = 6/91 (6%)
Query: 896 SGDGRVCVAIDECELDMRGGCHTDALCSYVGPGQSRCTCKLGFA--GDGYQCSPIDPCRA 953
SGD + +DEC+L C + +C PG S C C G+ +C D C
Sbjct: 1208 SGDLSLRRDVDECQLFRDQVCKS-GVCVNTAPGYS-CYCSNGYYYHTQRLECIDNDECAD 1265
Query: 954 GNGGCHGLATCRAVGGGQRVCTCPPGFGGDG 984
C G VG CTC P DG
Sbjct: 1266 EEPACEGGRCVNTVGSYH--CTCEPPLVLDG 1294
Score = 32.7 bits (73), Expect = 4.7
Identities = 18/53 (33%), Positives = 21/53 (39%), Gaps = 5/53 (9%)
Query: 257 CHCPENY--HGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPGLV 307
C+C Y H + C+ D C D C CV G CTC P LV
Sbjct: 1242 CYCSNGYYYHTQRLECIDNDECADEEPACEGGR--CV-NTVGSYHCTCEPPLV 1291
Score = 32.0 bits (71), Expect = 8.1
Identities = 28/84 (33%), Positives = 36/84 (42%), Gaps = 8/84 (9%)
Query: 872 GCSENAECVPGSLGTHHCTCHKGWSGD--GRVCVAIDEC-ELDMRGGCHTDALCSYVGPG 928
GC+ N CV G C C G+ D CV I+EC E + +A C G
Sbjct: 1505 GCT-NGRCVRVPEG-FTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTD-G 1561
Query: 929 QSRCTCKLGFA--GDGYQCSPIDP 950
RC C+ GFA + C+P P
Sbjct: 1562 SFRCICRPGFAPTHQPHHCAPARP 1585
>gi|110347431 latent transforming growth factor beta binding protein 4
isoform a [Homo sapiens]
Length = 1624
Score = 100 bits (248), Expect = 2e-20
Identities = 86/284 (30%), Positives = 114/284 (40%), Gaps = 49/284 (17%)
Query: 1320 CCPGFFGTLCE-----------PCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFH----G 1364
C GF G+ CE PC G G+C D GS C C GF G
Sbjct: 698 CPAGFRGSACEEDVDECAQEPPPC---------GPGRC-DNTAGSFHCACPAGFRSRGPG 747
Query: 1365 TACE-VCELGRYGPNCTGVCDCAHGLCQEGLQGDGSCVCNVGWQ----GLRCDQKITSPQ 1419
C+ V E R P CT +G C E +G CVC +G+Q G C+ + +
Sbjct: 748 APCQDVDECARSPPPCT------YGRC-ENTEGSFQCVCPMGFQPNTAGSECED-VDECE 799
Query: 1420 CPRKCDPNANCVQDSAGASTCACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQ 1479
C P CV C +G+ + C++VD C+ G C PH +CT G
Sbjct: 800 NHLAC-PGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTN-TEGS 857
Query: 1480 RTCTCQDGY---MGDGELCQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGY-SGDGI 1535
C+C GY G C ++N CL C H EC+ T +C+C GY G
Sbjct: 858 FRCSCAPGYRAPSGRPGPCADVNECL-EGDFCFPHGECLNT-DGSFACTCAPGYRPGPRG 915
Query: 1536 RTCELLDPCSKNNGGCSPYATCKSTGDGQRTCTCDTAHTVGDGL 1579
+C +D CS+ + C +T DG C C H G L
Sbjct: 916 ASCLDVDECSEED--LCQSGICTNT-DGSFECICPPGHRAGPDL 956
Score = 77.8 bits (190), Expect = 1e-13
Identities = 74/261 (28%), Positives = 99/261 (37%), Gaps = 52/261 (19%)
Query: 739 PCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQCQE--DCG-----CVHGLC 791
PC G C + G+ C+C Y+ HG CQ+ +C C G C
Sbjct: 639 PC-DLGRC-ENTPGSFLCVCPAGYQAAP---------HGASCQDVDECTQSPGLCGRGAC 687
Query: 792 DNRPGSGGVCQQGTCAPGFSGRFCNESMGDCG----PTGLAQHCHLHARCVSQEGVARCR 847
N PGS + C GF G C E + +C P G RC + G C
Sbjct: 688 KNLPGSF----RCVCPAGFRGSACEEDVDECAQEPPPCG-------PGRCDNTAGSFHCA 736
Query: 848 CLDGFE--GDGFSCTPSNPCSH---PDRGGCSENAECVPGSLGTHHCTCHKGWSGD--GR 900
C GF G G C + C+ P G EN E G+ C C G+ + G
Sbjct: 737 CPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTE------GSFQCVCPMGFQPNTAGS 790
Query: 901 VCVAIDECELDMRGGCHTDALCSYVGPGQSRC-TCKLGFAGDGYQCSPIDPCRAGNGGCH 959
C +DECE + C + PG +C TC G +C+ +D C +G C
Sbjct: 791 ECEDVDECENHL--ACPGQECVN--SPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCG 846
Query: 960 GLATCRAVGGGQRVCTCPPGF 980
C G R C+C PG+
Sbjct: 847 PHGHCTNTEGSFR-CSCAPGY 866
Score = 76.6 bits (187), Expect = 3e-13
Identities = 92/319 (28%), Positives = 115/319 (36%), Gaps = 79/319 (24%)
Query: 1946 CHR--------NCVTTTWKPSC-CPGHY-----GSECQACPGGPSSP-CSDRGVCMDGMS 1990
CHR C T C CP Y G+ CQ SP RG C + +
Sbjct: 633 CHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKN-LP 691
Query: 1991 GSGQCLCRSGFAGTACEL-----------CAPG-----AFGPHCQA------------CR 2022
GS +C+C +GF G+ACE C PG A HC C+
Sbjct: 692 GSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQ 751
Query: 2023 -----------CTVHGRCDEGLGGSGSCFCDEGW----TGPRCEVQLELQPVCTPPCAPE 2067
CT +GRC E GS C C G+ G CE E + P E
Sbjct: 752 DVDECARSPPPCT-YGRC-ENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACP-GQE 808
Query: 2068 AVCRAGN-SCE-CSLGYEGDGRVCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPDY-- 2123
V G+ C C G+ CT D C G C H +C+ C+C P Y
Sbjct: 809 CVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRA 868
Query: 2124 -EGDGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGD--GLQCLEESEPP 2180
G C N C +G C H CL+T + C C GY G CL+
Sbjct: 869 PSGRPGPCADVNECLEG--DFCFPHGECLNTD-GSFACTCAPGYRPGPRGASCLD----- 920
Query: 2181 VDRCLGQPPPCHSDAMCTD 2199
VD C + C S +CT+
Sbjct: 921 VDEC-SEEDLCQS-GICTN 937
Score = 75.5 bits (184), Expect = 6e-13
Identities = 79/285 (27%), Positives = 109/285 (38%), Gaps = 49/285 (17%)
Query: 722 KGFFGPDCT---QCPGGFSNPCYGKGNCSDG-----------IQGNGACLCFPDYK---- 763
+G F C + P G PC C +G G+ AC C P Y+
Sbjct: 855 EGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPR 914
Query: 764 GIACHICSNPNKHGEQCQEDCGCVHGLCDNRPGSGG-VCQQGTCA-PGFSGRFCNESMGD 821
G +C ++C E+ C G+C N GS +C G A P + + +
Sbjct: 915 GASC-------LDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRE 967
Query: 822 CGPTGLAQHCHLHARCVSQEGVARC--RCLDGFE-GDGFSCTPSNPCSHPDRGGC-SENA 877
GP RC + G RC C G+ G +C + C C ++
Sbjct: 968 RGPALCGSQ-----RCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRC 1022
Query: 878 ECVPGSLGTHHCT--CHKGWSGD-GRVCVAIDECELDMRGGCHTDALCSYVGPGQSRCTC 934
E PGS + CT C G+ G C +DEC R C A+C + PG +C C
Sbjct: 1023 ENTPGS---YRCTPACDPGYQPTPGGGCQDVDECR--NRSFCGAHAVCQNL-PGSFQCLC 1076
Query: 935 KLGFAG--DGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCP 977
G+ G DG C ++ C G C G A C V G +C CP
Sbjct: 1077 DQGYEGARDGRHCVDVNECETLQGVC-GAALCENV-EGSFLCVCP 1119
Score = 71.2 bits (173), Expect = 1e-11
Identities = 81/312 (25%), Positives = 107/312 (34%), Gaps = 90/312 (28%)
Query: 719 GCCKGFFGPDCTQCPGGFSN-----PCYGKGNCS-----------DGIQGNGACLCFPDY 762
G C G CP GF + PC C+ + +G+ C+C +
Sbjct: 724 GRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGF 783
Query: 763 KGIACHICSNPNKHGEQCQEDCGCVHGL------CDNRPGSGGVCQQGTCAPGFS---GR 813
+ PN G +C++ C + L C N PGS Q TC G GR
Sbjct: 784 Q---------PNTAGSECEDVDECENHLACPGQECVNSPGS---FQCRTCPSGHHLHRGR 831
Query: 814 F-----CNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGDGFSCTPSNPCSHP 868
C+ CGP H C + EG RC C G+ P P
Sbjct: 832 CTDVDECSSGAPPCGP---------HGHCTNTEGSFRCSCAPGYRA---------PSGRP 873
Query: 869 DRGGCSENAECVPGSL-----------GTHHCTCHKGW--SGDGRVCVAIDEC---ELDM 912
G C++ EC+ G G+ CTC G+ G C+ +DEC +L
Sbjct: 874 --GPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQ 931
Query: 913 RGGC-HTDALCSYVGPGQSRCTCKLGFAG--DGYQCSPIDPCRAGNGGCHGLATCRAVGG 969
G C +TD G C C G D C +D CR G C G
Sbjct: 932 SGICTNTD--------GSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPG 983
Query: 970 GQR-VCTCPPGF 980
R V C PG+
Sbjct: 984 SYRCVRDCDPGY 995
Score = 70.9 bits (172), Expect = 2e-11
Identities = 81/318 (25%), Positives = 108/318 (33%), Gaps = 87/318 (27%)
Query: 1263 SHAEALREKCVNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRG-CSYTCAKKIQVPDCC 1321
+H ++CVN F+C ++C SG RG C+ P C
Sbjct: 800 NHLACPGQECVNSPGSFQC-----------RTCP--SGHHLHRGRCTDVDECSSGAPPCG 846
Query: 1322 P--------GFFGTLCEP---CPGGLGGVCSGHGQCQ--DRFLGSGECHCHEGFHGTACE 1368
P G F C P P G G C+ +C D GEC +G C
Sbjct: 847 PHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCA 906
Query: 1369 V-CELGRYGPNCTGVCDCAH-GLCQEGL----QGDGSCVCNVGWQG-------------- 1408
G G +C V +C+ LCQ G+ G C+C G +
Sbjct: 907 PGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECR 966
Query: 1409 ---------LRCDQKITSPQCPRKCDPN------------------------ANCVQDSA 1435
RC+ S +C R CDP A +++
Sbjct: 967 ERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTP 1026
Query: 1436 GASTC--ACAAGYSGN-GIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMG-- 1490
G+ C AC GY G C +VD C + C HA C + PG C C GY G
Sbjct: 1027 GSYRCTPACDPGYQPTPGGGCQDVDECRN-RSFCGAHAVCQNL-PGSFQCLCDQGYEGAR 1084
Query: 1491 DGELCQEINSCLIHHGGC 1508
DG C ++N C G C
Sbjct: 1085 DGRHCVDVNECETLQGVC 1102
Score = 65.1 bits (157), Expect = 9e-10
Identities = 74/268 (27%), Positives = 100/268 (37%), Gaps = 41/268 (15%)
Query: 100 CCPGYW----GSRCHECPGGAETP--CNGHGTCLDGMDRNGTCVCQENFRGSACQE---- 149
C GY G+ C + ++P C G G C + + + CVC FRGSAC+E
Sbjct: 656 CPAGYQAAPHGASCQDVDECTQSPGLC-GRGACKN-LPGSFRCVCPAGFRGSACEEDVDE 713
Query: 150 -CQDPNRFGPD-CQSVCSCVHGVCNHGPRGDG-SCLCFAGYTGPHCDQELPVCQELRCPQ 206
Q+P GP C + H C G R G C C + P C RC +
Sbjct: 714 CAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPC---QDVDECARSPPPCTYGRC-E 769
Query: 207 NTQCSAEAPSCRCLPGY--TQQGSECRAPNPCWPSPCSLLAQCSVSPKGQAQCH-CPENY 263
NT+ S + C C G+ GSEC + C +C SP G QC CP +
Sbjct: 770 NTEGSFQ---CVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSP-GSFQCRTCPSGH 825
Query: 264 HGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPGLVSINSNASAGCFAFCSP 323
H C D C+ C + G C+C PG A +G C+
Sbjct: 826 HLHRGRCTDVDECSSGAPPCGPHGHCT--NTEGSFRCSCAPGY-----RAPSGRPGPCAD 878
Query: 324 FS-------CDRSATCQVTADGKTSCVC 344
+ C C + DG +C C
Sbjct: 879 VNECLEGDFCFPHGEC-LNTDGSFACTC 905
Score = 54.3 bits (129), Expect = 2e-06
Identities = 64/221 (28%), Positives = 73/221 (33%), Gaps = 35/221 (15%)
Query: 783 DCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMG-DCGPTGL----AQHCH----- 832
+ G G+C P VC G C SG C G P G C
Sbjct: 541 ESGPSSGMCQRNPQ---VCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPP 597
Query: 833 -LHARCVSQEGVARCRCLDGFEGD--GFSCTPSNPCSHP----DRGGCSENAECVPGSLG 885
RC + G RC C GF C + C D G C E PGS
Sbjct: 598 CAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRC----ENTPGSF- 652
Query: 886 THHCTCHKGWSG--DGRVCVAIDECELDMRGGCHTDALCSYVGPGQSRCTCKLGFAGDGY 943
C C G+ G C +DEC G C A C + PG RC C GF G
Sbjct: 653 --LCVCPAGYQAAPHGASCQDVDECT-QSPGLCGRGA-CKNL-PGSFRCVCPAGFRGSAC 707
Query: 944 QCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGFGGDG 984
+ +D C C G C G C CP GF G
Sbjct: 708 E-EDVDECAQEPPPC-GPGRCDNTAGSFH-CACPAGFRSRG 745
Score = 54.3 bits (129), Expect = 2e-06
Identities = 64/257 (24%), Positives = 83/257 (32%), Gaps = 72/257 (28%)
Query: 1945 GCHRNCVTT--TWKPSCCPGHYGSECQACPGGPSSPCSDRGVCMDG--MSGSGQCLCRSG 2000
G H +C T +++ SC PG+ P G PC+D C++G G+CL G
Sbjct: 846 GPHGHCTNTEGSFRCSCAPGY------RAPSGRPGPCADVNECLEGDFCFPHGECLNTDG 899
Query: 2001 -FAGTACELCAPGAFGPHC-QACRCTVHGRCDEGL----GGSGSCFCDEGW-TGPRCEVQ 2053
FA T PG G C C+ C G+ GS C C G GP
Sbjct: 900 SFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASC 959
Query: 2054 LELQPV---------------------CTPPC------APEAVCRAGNSCE--------- 2077
L++ C C PE C + C+
Sbjct: 960 LDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGA 1019
Query: 2078 ---------------CSLGYEGD-GRVCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLP 2121
C GY+ G C D C++ C HA C + C C
Sbjct: 1020 QRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRN-RSFCGAHAVCQNLPGSFQCLCDQ 1078
Query: 2122 DYEG--DGWSCRARNPC 2136
YEG DG C N C
Sbjct: 1079 GYEGARDGRHCVDVNEC 1095
Score = 52.8 bits (125), Expect = 4e-06
Identities = 45/154 (29%), Positives = 66/154 (42%), Gaps = 13/154 (8%)
Query: 1421 PRKCDPNANCVQDSAGASTCACAAGY--SGNGIFCSEVDPCAHGHGGCSPHANCTKVAPG 1478
P+ C P C+ +G TCAC +G+ S G C +VD C C+P C +PG
Sbjct: 553 PQVCGPG-RCISRPSGY-TCACDSGFRLSPQGTRCIDVDECRRVPPPCAP-GRCEN-SPG 608
Query: 1479 QRTCTCQDGYMGDGEL--CQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGY-SGDGI 1535
C C G+ C +++ C C + C T P C C GY +
Sbjct: 609 SFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDL-GRCENT-PGSFLCVCPAGYQAAPHG 666
Query: 1536 RTCELLDPCSKNNGGCSPYATCKSTGDGQRTCTC 1569
+C+ +D C+++ G C A CK+ G C C
Sbjct: 667 ASCQDVDECTQSPGLCGRGA-CKNL-PGSFRCVC 698
Score = 45.8 bits (107), Expect = 5e-04
Identities = 67/266 (25%), Positives = 91/266 (34%), Gaps = 57/266 (21%)
Query: 654 CSEEQHKIVAGSCVDCQALNTSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKGCASYCNQ 713
C E G C++ TC P Y P G + L S +
Sbjct: 882 CLEGDFCFPHGECLNTDGSFACTCAPG------------YRPGPRGASCLDVDECS--EE 927
Query: 714 TIMEQGCCKGFFGP-DCTQCPGGFSNP----------CYGKGNCSDGIQ------GNGAC 756
+ + G C G +C PG + P C +G G Q G+ C
Sbjct: 928 DLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRC 987
Query: 757 L--CFPDYKGIACHICSNPNKHGEQCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFS--- 811
+ C P Y C + ++ E E CG C+N PGS C PG+
Sbjct: 988 VRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQR--CENTPGSYRCTP--ACDPGYQPTP 1043
Query: 812 GRFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEG--DGFSCTPSNPCSHPD 869
G C + + +C C HA C + G +C C G+EG DG C N C
Sbjct: 1044 GGGCQD-VDECRNRSF---CGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNEC-ETL 1098
Query: 870 RGGCS----ENAECVPGSLGTHHCTC 891
+G C EN E G+ C C
Sbjct: 1099 QGVCGAALCENVE------GSFLCVC 1118
Score = 39.7 bits (91), Expect = 0.039
Identities = 33/117 (28%), Positives = 45/117 (38%), Gaps = 26/117 (22%)
Query: 1442 CAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINSC 1501
C G+ C +VD CA G G C H C G TC C DG++ D +SC
Sbjct: 344 CPTGFERVNGSCEDVDECATG-GRCQ-HGECANTRGGY-TCVCPDGFLLDSSR----SSC 396
Query: 1502 LIHH---------------GGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLDP 1543
+ H GGC + + +Q+ C R G + R C+L P
Sbjct: 397 ISQHVISEAKGPCFRVLRDGGCSL--PILRNITKQICCCSRVGKAWG--RGCQLCPP 449
Score = 37.0 bits (84), Expect = 0.25
Identities = 56/227 (24%), Positives = 79/227 (34%), Gaps = 41/227 (18%)
Query: 749 GIQGNGACLCFPDYKGIACHICSNPNKHGEQCQEDCGCVHGLCDNRPGSGGVCQQGTCAP 808
G G+G C+ D A C N QE C C G G C+ C
Sbjct: 1174 GPVGSGRRECYFDTA--APDACDNILARNVTWQECC------CTVGEGWGSGCRIQQCPG 1225
Query: 809 GFSGRF---CNESMGDCGPTGL------AQHCHLHARCVSQEGVA-------RCRCLDGF 852
+ + C G P+G C L V + GV C C +G+
Sbjct: 1226 TETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGY 1285
Query: 853 --EGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDG--RVCVAIDEC 908
C ++ C+ D E CV ++G++HCTC DG R CV+ +
Sbjct: 1286 YYHTQRLECIDNDECA--DEEPACEGGRCV-NTVGSYHCTCEPPLVLDGSQRRCVSNESQ 1342
Query: 909 ELDMRGG-----CHTDALCSYVGPGQ----SRCTCKLGFAGDGYQCS 946
LD G D +CS+ + + C C G A G C+
Sbjct: 1343 SLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYGEAW-GMDCA 1388
Score = 36.6 bits (83), Expect = 0.33
Identities = 48/169 (28%), Positives = 68/169 (40%), Gaps = 20/169 (11%)
Query: 855 DGFS-CTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGRVCVAIDECELDMR 913
DG+S + C RGG E A +PG L T C G G + + +C+L
Sbjct: 278 DGYSDASGFGYCFRELRGG--ECASPLPG-LRTQEVCCR----GAG-LAWGVHDCQLCSE 329
Query: 914 GGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRV 973
+++ + + GP C GF C +D C G HG C GG
Sbjct: 330 RLGNSERVSAPDGP------CPTGFERVNGSCEDVDECATGGRCQHG--ECANTRGGY-T 380
Query: 974 CTCPPGFGGDGFSCYGDIFRELEANAHFSIFYQWLKSAGITLPADRRVT 1022
C CP GF D S I + + + A F + L+ G +LP R +T
Sbjct: 381 CVCPDGFLLDS-SRSSCISQHVISEAKGPCF-RVLRDGGCSLPILRNIT 427
Score = 36.2 bits (82), Expect = 0.43
Identities = 26/92 (28%), Positives = 38/92 (41%), Gaps = 9/92 (9%)
Query: 778 EQCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFS---GRFCNESMGDCGPTGLAQHCHLH 834
E+C GC +G C P G C+ C G+ R + +C A ++
Sbjct: 1535 EECGILDGCTNGRCVRVP-EGFTCR---CFDGYRLDMTRMACVDINECDEAEAASPLCVN 1590
Query: 835 ARCVSQEGVARCRCLDGF--EGDGFSCTPSNP 864
ARC++ +G RC C GF C P+ P
Sbjct: 1591 ARCLNTDGSFRCICRPGFAPTHQPHHCAPARP 1622
Score = 35.0 bits (79), Expect = 0.95
Identities = 44/169 (26%), Positives = 58/169 (34%), Gaps = 27/169 (15%)
Query: 753 NGACLCFPDYKGIACHICSNPNKHGEQCQEDCGCVHG-----LCDNRPGSGG--VCQQGT 805
+G CF + +G C + E C G G LC R G+ G
Sbjct: 284 SGFGYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGP 343
Query: 806 CAPGFS--GRFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGF--EGDGFSCTP 861
C GF C E + +C G QH C + G C C DGF + SC
Sbjct: 344 CPTGFERVNGSC-EDVDECATGGRCQH----GECANTRGGYTCVCPDGFLLDSSRSSCIS 398
Query: 862 SN-------PCSHPDR-GGCSENAECVPGSLGTHHCTCHKGWSGDGRVC 902
+ PC R GGCS + ++ C C + GR C
Sbjct: 399 QHVISEAKGPCFRVLRDGGCSLP---ILRNITKQICCCSRVGKAWGRGC 444
Score = 34.3 bits (77), Expect = 1.6
Identities = 28/91 (30%), Positives = 35/91 (38%), Gaps = 6/91 (6%)
Query: 896 SGDGRVCVAIDECELDMRGGCHTDALCSYVGPGQSRCTCKLGFA--GDGYQCSPIDPCRA 953
SGD + +DEC+L C + +C PG S C C G+ +C D C
Sbjct: 1245 SGDLSLRRDVDECQLFRDQVCKS-GVCVNTAPGYS-CYCSNGYYYHTQRLECIDNDECAD 1302
Query: 954 GNGGCHGLATCRAVGGGQRVCTCPPGFGGDG 984
C G VG CTC P DG
Sbjct: 1303 EEPACEGGRCVNTVGSYH--CTCEPPLVLDG 1331
Score = 32.7 bits (73), Expect = 4.7
Identities = 18/53 (33%), Positives = 21/53 (39%), Gaps = 5/53 (9%)
Query: 257 CHCPENY--HGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPGLV 307
C+C Y H + C+ D C D C CV G CTC P LV
Sbjct: 1279 CYCSNGYYYHTQRLECIDNDECADEEPACEGGR--CV-NTVGSYHCTCEPPLV 1328
Score = 32.0 bits (71), Expect = 8.1
Identities = 28/84 (33%), Positives = 36/84 (42%), Gaps = 8/84 (9%)
Query: 872 GCSENAECVPGSLGTHHCTCHKGWSGD--GRVCVAIDEC-ELDMRGGCHTDALCSYVGPG 928
GC+ N CV G C C G+ D CV I+EC E + +A C G
Sbjct: 1542 GCT-NGRCVRVPEG-FTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTD-G 1598
Query: 929 QSRCTCKLGFA--GDGYQCSPIDP 950
RC C+ GFA + C+P P
Sbjct: 1599 SFRCICRPGFAPTHQPHHCAPARP 1622
>gi|144953895 nidogen 2 precursor [Homo sapiens]
Length = 1375
Score = 99.4 bits (246), Expect = 4e-20
Identities = 58/168 (34%), Positives = 75/168 (44%), Gaps = 13/168 (7%)
Query: 831 CHLHARCVSQEGVA-RCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHC 889
C ARC GV C C G++GDG +C N C+ C N+ C+ G++ C
Sbjct: 770 CDTTARCHPGTGVDYTCECASGYQGDGRNCVDENECATGFHR-CGPNSVCI-NLPGSYRC 827
Query: 890 TCHKGW--SGDGRVCVAIDECELDMRGGCHT-----DALCSYVGPGQSRCTCKLGFAGDG 942
C G+ + D C+ I G HT A C + G C C G+AGDG
Sbjct: 828 ECRSGYEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYAGDG 887
Query: 943 YQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGFGGDGFSCYGD 990
+QC+ +D C CH ATC G C C PG+ GDGF C D
Sbjct: 888 HQCTDVDEC--SENRCHPAATCYNTPGSFS-CRCQPGYYGDGFQCIPD 932
Score = 97.1 bits (240), Expect = 2e-19
Identities = 58/170 (34%), Positives = 80/170 (47%), Gaps = 22/170 (12%)
Query: 1424 CDPNANCVQDSAGASTCACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCT 1483
CD A C + TC CA+GY G+G C + + CA G C P++ C + PG C
Sbjct: 770 CDTTARCHPGTGVDYTCECASGYQGDGRNCVDENECATGFHRCGPNSVCINL-PGSYRCE 828
Query: 1484 CQDGYMGDGELCQEINSCLI-------HHGGCHI-----HAECIPTGPQQVSCSCREGYS 1531
C+ GY E + ++C++ G H A C+ G SC+C GY+
Sbjct: 829 CRSGY----EFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYA 884
Query: 1532 GDGIRTCELLDPCSKNNGGCSPYATCKSTGDGQRTCTCDTAHTVGDGLTC 1581
GDG C +D CS+N C P ATC +T G +C C + GDG C
Sbjct: 885 GDG-HQCTDVDECSENR--CHPAATCYNT-PGSFSCRCQPGY-YGDGFQC 929
Score = 87.0 bits (214), Expect = 2e-16
Identities = 51/136 (37%), Positives = 65/136 (47%), Gaps = 11/136 (8%)
Query: 860 TPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGRVCVAIDECELDMRGGCHTD 919
TP NPC + C A C PG+ + C C G+ GDGR CV +EC C +
Sbjct: 758 TPGNPC-YDGSHMCDTTARCHPGTGVDYTCECASGYQGDGRNCVDENECATGFH-RCGPN 815
Query: 920 ALCSYVGPGQSRCTCKLG--FAGDGYQC----SPIDPCRAGNGGC--HGLATCRAVGGGQ 971
++C + PG RC C+ G FA D + C P +PC G+ C G A C GG
Sbjct: 816 SVCINL-PGSYRCECRSGYEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGST 874
Query: 972 RVCTCPPGFGGDGFSC 987
C C PG+ GDG C
Sbjct: 875 FSCACLPGYAGDGHQC 890
Score = 82.4 bits (202), Expect = 5e-15
Identities = 55/176 (31%), Positives = 73/176 (41%), Gaps = 19/176 (10%)
Query: 2023 CTVHGRCDEGLGGSGSCFCDEGWTGP--RCEVQLELQPVCTPPCAPEAVC---RAGNSCE 2077
C RC G G +C C G+ G C + E C P +VC CE
Sbjct: 770 CDTTARCHPGTGVDYTCECASGYQGDGRNCVDENECA-TGFHRCGPNSVCINLPGSYRCE 828
Query: 2078 CSLGYE--GDGRVCTV----ADLCQDGHGGCSEHANCSQV---GTMVTCTCLPDYEGDGW 2128
C GYE D C + A+ C+DG C+ V G+ +C CLP Y GDG
Sbjct: 829 CRSGYEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYAGDGH 888
Query: 2129 SCRARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGDGLQCLEESEPPVDRC 2184
C + C++ C A C +T + C C GY GDG QC+ +S + C
Sbjct: 889 QCTDVDECSENR---CHPAATCYNTP-GSFSCRCQPGYYGDGFQCIPDSTSSLTPC 940
Score = 80.5 bits (197), Expect = 2e-14
Identities = 53/179 (29%), Positives = 74/179 (41%), Gaps = 19/179 (10%)
Query: 1382 VCDCAHGLCQEGLQGDGSCVCNVGWQ--GLRCDQKITSPQCPRKCDPNANCVQDSAGAST 1439
+CD C G D +C C G+Q G C + +C PN+ C+ + G+
Sbjct: 769 MCDTT-ARCHPGTGVDYTCECASGYQGDGRNCVDENECATGFHRCGPNSVCI-NLPGSYR 826
Query: 1440 CACAAGYSGNG------IFCSEVDPCAHGHGGCSP--HANCTKVAPGQRTCTCQDGYMGD 1491
C C +GY + +PC G C+P A C +C C GY GD
Sbjct: 827 CECRSGYEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYAGD 886
Query: 1492 GELCQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIR----TCELLDPCSK 1546
G C +++ C CH A C T P SC C+ GY GDG + + L PC +
Sbjct: 887 GHQCTDVDEC--SENRCHPAATCYNT-PGSFSCRCQPGYYGDGFQCIPDSTSSLTPCEQ 942
Score = 79.3 bits (194), Expect = 4e-14
Identities = 56/171 (32%), Positives = 70/171 (40%), Gaps = 24/171 (14%)
Query: 2064 CAPEAVCRAGN----SCECSLGYEGDGRVCTVADLCQDGHGGCSEHANCSQVGTMVTCTC 2119
C A C G +CEC+ GY+GDGR C + C G C ++ C + C C
Sbjct: 770 CDTTARCHPGTGVDYTCECASGYQGDGRNCVDENECATGFHRCGPNSVCINLPGSYRCEC 829
Query: 2120 LPDYE--GDGWSC----RARNPCTDG-HRGGCSEHANCLSTGLNTRRCECHAGYVGDGLQ 2172
YE D +C NPC DG H + A C+ G +T C C GY GDG Q
Sbjct: 830 RSGYEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYAGDGHQ 889
Query: 2173 CLEESEPPVDRCLGQPPPCHSDAMCTDLHFQEKRAGVFHLQATSGPYGLNF 2223
C + VD C CH A C + G F + G YG F
Sbjct: 890 CTD-----VDEC--SENRCHPAATCYN------TPGSFSCRCQPGYYGDGF 927
Score = 68.2 bits (165), Expect = 1e-10
Identities = 43/132 (32%), Positives = 53/132 (40%), Gaps = 9/132 (6%)
Query: 1457 DPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINSCLIHHGGCHIHAECIP 1516
+PC G C A C TC C GY GDG C + N C C ++ CI
Sbjct: 761 NPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGDGRNCVDENECATGFHRCGPNSVCIN 820
Query: 1517 TGPQQVSCSCREGYS-GDGIRTCELL----DPCSKNNGGCSP--YATCKSTGDGQRTCTC 1569
P C CR GY D TC L+ +PC + C+P A C G +C C
Sbjct: 821 L-PGSYRCECRSGYEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCAC 879
Query: 1570 DTAHTVGDGLTC 1581
+ GDG C
Sbjct: 880 LPGY-AGDGHQC 890
Score = 65.9 bits (159), Expect = 5e-10
Identities = 60/229 (26%), Positives = 82/229 (35%), Gaps = 42/229 (18%)
Query: 120 CNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPN-------RFGPDCQSVCSCVHGVCN 172
C+ C G + TC C ++G + C D N R GP+ VC
Sbjct: 770 CDTTARCHPGTGVDYTCECASGYQGDG-RNCVDENECATGFHRCGPN---------SVCI 819
Query: 173 HGPRGDGSCLCFAGY------------TGPH--CDQELPVCQELRCPQNTQCSAEAPSCR 218
+ P G C C +GY T P C+ C + SC
Sbjct: 820 NLP-GSYRCECRSGYEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCA 878
Query: 219 CLPGYTQQGSECRAPNPCWPSPCSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTD 278
CLPGY G +C + C + C A C +P G C C Y+GDG C+P T
Sbjct: 879 CLPGYAGDGHQCTDVDECSENRCHPAATCYNTP-GSFSCRCQPGYYGDGFQCIPDS--TS 935
Query: 279 NLGGCPSNS--TLCVYQKPGQAF----CTCRPGLVSINSNASAGCFAFC 321
+L C Y PG F C + + + + S G F +C
Sbjct: 936 SLTPCEQQQRHAQAQYAYPGARFHIPQCDEQGNFLPLQCHGSTG-FCWC 983
Score = 58.5 bits (140), Expect = 8e-08
Identities = 44/149 (29%), Positives = 54/149 (36%), Gaps = 13/149 (8%)
Query: 216 SCRCLPGYTQQGSECRAPNPCWPS--PCSLLAQCSVSPKGQAQCHCPENYH--GDGMVCL 271
+C C GY G C N C C + C P G +C C Y D C+
Sbjct: 785 TCECASGYQGDGRNCVDENECATGFHRCGPNSVCINLP-GSYRCECRSGYEFADDRHTCI 843
Query: 272 ----PKDPCTDNLGGC-PSNSTLCVYQKPGQAFCTCRPGLVSINSNASAGCFAFCSPFSC 326
P +PC D C P+ CV+ C C PG + CS C
Sbjct: 844 LITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYAGDGHQCTD--VDECSENRC 901
Query: 327 DRSATCQVTADGKTSCVCRESEVGDGRAC 355
+ATC T G SC C+ GDG C
Sbjct: 902 HPAATCYNTP-GSFSCRCQPGYYGDGFQC 929
Score = 55.5 bits (132), Expect = 7e-07
Identities = 39/147 (26%), Positives = 53/147 (36%), Gaps = 18/147 (12%)
Query: 222 GYTQQGSECRAPNPCWPSP--CSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTDN 279
G ++ S+ NPC+ C A+C C C Y GDG C+ ++ C
Sbjct: 749 GPVKEDSDPTPGNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGDGRNCVDENECATG 808
Query: 280 LGGCPSNSTLCVYQKPGQAFCTCRPG-----------LVSINSNASAGCFAFCSPFSCDR 328
C NS +C+ PG C CR G L++ +N C+P
Sbjct: 809 FHRCGPNS-VCI-NLPGSYRCECRSGYEFADDRHTCILITPPANPCEDGSHTCAPAG--- 863
Query: 329 SATCQVTADGKTSCVCRESEVGDGRAC 355
A C SC C GDG C
Sbjct: 864 QARCVHHGGSTFSCACLPGYAGDGHQC 890
Score = 52.4 bits (124), Expect = 6e-06
Identities = 55/208 (26%), Positives = 72/208 (34%), Gaps = 51/208 (24%)
Query: 696 DPTGLNVLKKGCASYCNQTIMEQGCCKGFFGPDCT-QCPGGFSNP---CYGKGNCSDGIQ 751
DPT N G + C+ T C G D T +C G+ C + C+ G
Sbjct: 756 DPTPGNPCYDG-SHMCDTTAR----CHPGTGVDYTCECASGYQGDGRNCVDENECATGFH 810
Query: 752 G---NGACLCFPDYKGIAC----------HIC------SNPNKHGEQCQEDCG---CVHG 789
N C+ P C H C +NP + G G CVH
Sbjct: 811 RCGPNSVCINLPGSYRCECRSGYEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVH- 869
Query: 790 LCDNRPGSGGVCQQGTCAPGFSG--RFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCR 847
GG C PG++G C + + +C CH A C + G CR
Sbjct: 870 -------HGGSTFSCACLPGYAGDGHQCTD-VDECSEN----RCHPAATCYNTPGSFSCR 917
Query: 848 CLDGFEGDGFSCTPSN-----PCSHPDR 870
C G+ GDGF C P + PC R
Sbjct: 918 CQPGYYGDGFQCIPDSTSSLTPCEQQQR 945
Score = 49.7 bits (117), Expect = 4e-05
Identities = 49/166 (29%), Positives = 58/166 (34%), Gaps = 32/166 (19%)
Query: 1950 CVTTTWKPSCCPG---HYGSECQACPGGPSSPCSDRGVCMDG------------MSGSGQ 1994
C TT C PG Y EC + G C D C G + GS +
Sbjct: 770 CDTTA---RCHPGTGVDYTCECASGYQGDGRNCVDENECATGFHRCGPNSVCINLPGSYR 826
Query: 1995 CLCRSGFAGT----ACELCAPGA----FGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWT 2046
C CRSG+ C L P A G H C RC G + SC C G+
Sbjct: 827 CECRSGYEFADDRHTCILITPPANPCEDGSH--TCAPAGQARCVHHGGSTFSCACLPGYA 884
Query: 2047 GPRCEVQLELQPVCTPPCAPEAVC---RAGNSCECSLGYEGDGRVC 2089
G + ++ C P A C SC C GY GDG C
Sbjct: 885 GDGHQC-TDVDECSENRCHPAATCYNTPGSFSCRCQPGYYGDGFQC 929
Score = 38.1 bits (87), Expect = 0.11
Identities = 17/39 (43%), Positives = 21/39 (53%), Gaps = 1/39 (2%)
Query: 1457 DPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELC 1495
+ C H H CS HA CT A G C CQ + G+G+ C
Sbjct: 486 ETCEHNHRQCSRHAFCTDYATG-FCCHCQSKFYGNGKHC 523
Score = 37.0 bits (84), Expect = 0.25
Identities = 24/79 (30%), Positives = 34/79 (43%), Gaps = 5/79 (6%)
Query: 2093 DLCQDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWSCRARNPCTDGHR--GGCSEHANC 2150
+ C+ H CS HA C+ T C C + G+G C P HR G S H +
Sbjct: 486 ETCEHNHRQCSRHAFCTDYATGFCCHCQSKFYGNGKHCL---PEGAPHRVNGKVSGHLHV 542
Query: 2151 LSTGLNTRRCECHAGYVGD 2169
T ++ + HA VG+
Sbjct: 543 GHTPVHFTDVDLHAYIVGN 561
Score = 35.0 bits (79), Expect = 0.95
Identities = 17/55 (30%), Positives = 25/55 (45%)
Query: 933 TCKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGFGGDGFSC 987
T ++G + +P +PC G+ C A C G C C G+ GDG +C
Sbjct: 745 TNQIGPVKEDSDPTPGNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGDGRNC 799
Score = 32.3 bits (72), Expect = 6.2
Identities = 18/49 (36%), Positives = 23/49 (46%), Gaps = 6/49 (12%)
Query: 2133 RNPCTDGHRGGCSEHANCL--STGLNTRRCECHAGYVGDGLQCLEESEP 2179
+ C HR CS HA C +TG C C + + G+G CL E P
Sbjct: 485 KETCEHNHRQ-CSRHAFCTDYATGFC---CHCQSKFYGNGKHCLPEGAP 529
>gi|55770876 notch4 preproprotein [Homo sapiens]
Length = 2003
Score = 99.0 bits (245), Expect = 5e-20
Identities = 105/357 (29%), Positives = 138/357 (38%), Gaps = 71/357 (19%)
Query: 1220 FYNHSGQPEVNHVPLEGPMLEAPGRSLIGLSGVLTVGSSRCLHSHAEALREKCVNCTRRF 1279
F H+ + +VN + PG G S T+GS +CL
Sbjct: 186 FEGHACERDVNEC------FQDPGPCPKGTSCHNTLGSFQCL------------------ 221
Query: 1280 RCTQGFQLQDTPRKSCVYRSGFSFSRGCSY--TCAKKIQVPD------CCPGFFGTLCEP 1331
C G Q+ PR C R+G RGCS TC + C PGF G CE
Sbjct: 222 -CPVG---QEGPR--CELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEV 275
Query: 1332 CPGG-LGGVCSGHGQCQDRFLGSGECHCHEGFHGTAC--EVCELGRYGPNCTGVCDCAHG 1388
P + C G CQD L + C C E + G C +V E GP C +G
Sbjct: 276 NPDNCVSHQCQNGGTCQDG-LDTYTCLCPETWTGWDCSEDVDECETQGPP-----HCRNG 329
Query: 1389 LCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTCACAAGYSG 1448
+ G CVC GW G C++ + C P + C+ D G+ +C C G +
Sbjct: 330 GTCQNSAGSFHCVCVSGWGGTSCEENL-DDCIAATCAPGSTCI-DRVGSFSCLCPPGRT- 386
Query: 1449 NGIFCSEVDPC----AHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELC-QEINSCLI 1503
G+ C D C HG CS T G C CQ GY G C Q+++ CL+
Sbjct: 387 -GLLCHLEDMCLSQPCHGDAQCS-----TNPLTGSTLCLCQPGY--SGPTCHQDLDECLM 438
Query: 1504 HHGG---CHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATC 1557
G C C+ T P +C C GY+G CE D + C P +TC
Sbjct: 439 AQQGPSPCEHGGSCLNT-PGSFNCLCPPGYTGS---RCE-ADHNECLSQPCHPGSTC 490
Score = 97.8 bits (242), Expect = 1e-19
Identities = 101/348 (29%), Positives = 122/348 (35%), Gaps = 92/348 (26%)
Query: 1959 CCPGHYGSECQA-CPGGPSSPCSDRGVCMDGMSGSGQCLCRSGFAGTACE--LCAPGAFG 2015
C PG G CQ S PC C+D + G+ CLC SGF G CE LCAP
Sbjct: 577 CLPGFEGPRCQTEVDECLSDPCPVGASCLD-LPGAFFCLCPSGFTGQLCEVPLCAPNLCQ 635
Query: 2016 PHCQACR-----------------------CTVH-GRCDEGLGGSGSCFCDEGWTGPRCE 2051
P Q C+ CT H G C SC CD GWTGP CE
Sbjct: 636 PK-QICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRS-----SCVCDVGWTGPECE 689
Query: 2052 VQLELQPVCTPPCAPEAVC---RAGNSCECSLGYEG------------------------ 2084
EL + PCA C +G +C C GY G
Sbjct: 690 A--ELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPS 747
Query: 2085 -DGRVCT-----VADLCQDGHGGCSEHANCSQVGTMV------TCTCLPDYEGDGWSCRA 2132
G CT CQ C A C GT V +C C ++G +
Sbjct: 748 PGGYYCTCPPSHTGPQCQTSTDYCVS-APCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKL 806
Query: 2133 RNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGDGLQCLEESEPPVDRCLGQPPPCH 2192
R C D C A C + RC C GY G Q L +D C +P P +
Sbjct: 807 RPSCAD---SPCRNRATCQDSPQGP-RCLCPTGYTGGSCQTL------MDLCAQKPCPRN 856
Query: 2193 SDAMCTDLHFQEKRAGVFHLQATSGPY-GLNFSEAEAACEAQGAVLAS 2239
S + T F LQ +GP L S + A +QG ++S
Sbjct: 857 SHCLQTGPSFH-----CLCLQGWTGPLCNLPLSSCQKAALSQGIDVSS 899
Score = 97.8 bits (242), Expect = 1e-19
Identities = 84/312 (26%), Positives = 107/312 (34%), Gaps = 76/312 (24%)
Query: 100 CCPGYWGSRCHEC--PGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFG 157
C G+ G RC P A++PC TC D + C+C + G +CQ D
Sbjct: 793 CAMGFQGPRCEGKLRPSCADSPCRNRATCQDS-PQGPRCLCPTGYTGGSCQTLMDLCAQK 851
Query: 158 PDCQSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQELPVCQELR----------CPQN 207
P C C+ GP CLC G+TGP C+ L CQ+ C
Sbjct: 852 P-CPRNSHCLQT----GP--SFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNG 904
Query: 208 TQCSAEAPS--CRCLPGYTQQGSECRAP-NPCWPSPCSLLAQCSVSPKGQAQCHCPENYH 264
C PS C C PG+ QGS C+ NPC PC A C P G C C Y
Sbjct: 905 GLCVDSGPSYFCHCPPGF--QGSLCQDHVNPCESRPCQNGATCMAQPSGYL-CQCAPGYD 961
Query: 265 GDGMVCLPKDPCTDNLGGCPS----NSTLCVYQKPGQAFCTCRPGLVSI----------- 309
G C+ L C S N C KPG C C PG V +
Sbjct: 962 GQN--------CSKELDACQSQPCHNHGTCT-PKPGGFHCACPPGFVGLRCEGDVDECLD 1012
Query: 310 ---NSNASAGCFAFCSPFSCD-----------------------RSATCQVTADGKTSCV 343
+ +A C + + F C TC+ TA +
Sbjct: 1013 QPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFI 1072
Query: 344 CRESEVGDGRAC 355
C + +G C
Sbjct: 1073 CHCPKGFEGPTC 1084
Score = 96.7 bits (239), Expect = 3e-19
Identities = 71/251 (28%), Positives = 102/251 (40%), Gaps = 23/251 (9%)
Query: 114 GGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQ---ECQDPN--RFGPDCQSVCSCVH 168
G PC GTCL GTC C F G CQ CQ+ + G CQ++
Sbjct: 29 GSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPL 88
Query: 169 GVCNHGPRGDGS--CLCFAGYTGPHCDQEL-PVCQELRCPQNTQCSAEA---PSCRCLPG 222
G+ + S C C G+TG C +L C C + +C +A P C C+PG
Sbjct: 89 GLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPG 148
Query: 223 YTQQGSECRAPNPCWPSPCSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGG 282
+T G +C+ + C +PC C ++ Q QCHCP + G + C + G
Sbjct: 149 WT--GEQCQLRDFCSANPCVNGGVC-LATYPQIQCHCPPGFEGHACE-RDVNECFQDPGP 204
Query: 283 CPSNSTLCVYQKPGQAFCTCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVTADGKTS- 341
CP ++ + G C C G AG C P C TCQ+ + ++
Sbjct: 205 CPKGTS--CHNTLGSFQCLCPVGQEGPRCELRAGP---CPPRGCSNGGTCQLMPEKDSTF 259
Query: 342 --CVCRESEVG 350
C+C +G
Sbjct: 260 HLCLCPPGFIG 270
Score = 95.1 bits (235), Expect = 8e-19
Identities = 85/316 (26%), Positives = 111/316 (35%), Gaps = 50/316 (15%)
Query: 54 TCPSGWLRELPDQITQDCRYEVQLGGSMVSMSGCRRKCRKQVVQKACCPGYWGSRCHECP 113
TCP+G+ + C L G + S C C P + G +C
Sbjct: 716 TCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYC-------TCPPSHTGPQCQTST 768
Query: 114 GGA-ETPCNGHGTCLDGMDRNGT--CVCQENFRGSACQECQDPNRFGPDCQSVCSCVHGV 170
PC GTC++ R GT C+C F+G C+ + P C
Sbjct: 769 DYCVSAPCFNGGTCVN---RPGTFSCLCAMGFQGPRCE-----GKLRPSCADSPCRNRAT 820
Query: 171 CNHGPRGDGSCLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAPS--CRCLPGYTQQGS 228
C P+G CLC GYTG C + +C + CP+N+ C PS C CL G+T G
Sbjct: 821 CQDSPQGP-RCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWT--GP 877
Query: 229 ECRAP-NPCWPSPCSLLAQCS---------VSPKGQAQCHCPENYHGDGMVCLPKDPCTD 278
C P + C + S S V CHCP + G C D
Sbjct: 878 LCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQG--------SLCQD 929
Query: 279 NLGGCPS----NSTLCVYQKPGQAFCTCRPGLVSINSNASAGCFAFCSPFSCDRSATCQV 334
++ C S N C+ Q P C C PG N + C C TC
Sbjct: 930 HVNPCESRPCQNGATCMAQ-PSGYLCQCAPGYDGQNCSKELDA---CQSQPCHNHGTC-T 984
Query: 335 TADGKTSCVCRESEVG 350
G C C VG
Sbjct: 985 PKPGGFHCACPPGFVG 1000
Score = 95.1 bits (235), Expect = 8e-19
Identities = 90/327 (27%), Positives = 120/327 (36%), Gaps = 73/327 (22%)
Query: 720 CCKGFFGPDCTQ-CPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGE 778
C G+ GP C++ S PC G+C+ G C C P + G C + +
Sbjct: 717 CPTGYTGPTCSEEMTACHSGPCLNGGSCNPS-PGGYYCTCPPSHTGPQCQTST------D 769
Query: 779 QCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCV 838
C G C NRPG+ CA GF G C G P+ C A C
Sbjct: 770 YCVSAPCFNGGTCVNRPGTFSCL----CAMGFQGPRCE---GKLRPSCADSPCRNRATCQ 822
Query: 839 SQEGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGD 898
RC C G+ G G T + C+ C N+ C+ + HC C +GW+G
Sbjct: 823 DSPQGPRCLCPTGYTG-GSCQTLMDLCAQKP---CPRNSHCLQTG-PSFHCLCLQGWTGP 877
Query: 899 GRVC-VAIDECE-------LDMRGGCHTDALCSYVGPGQSRCTCKLGFAGD--------- 941
+C + + C+ +D+ CH LC GP C C GF G
Sbjct: 878 --LCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYF-CHCPPGFQGSLCQDHVNPC 934
Query: 942 ----------------GY--QCSP----------IDPCRAGNGGCHGLATCRAVGGGQRV 973
GY QC+P +D C++ CH TC GG
Sbjct: 935 ESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQP--CHNHGTCTPKPGGFH- 991
Query: 974 CTCPPGFGGDGFSCYGDIFRELEANAH 1000
C CPPGF G C GD+ L+ H
Sbjct: 992 CACPPGF--VGLRCEGDVDECLDQPCH 1016
Score = 94.7 bits (234), Expect = 1e-18
Identities = 88/295 (29%), Positives = 116/295 (39%), Gaps = 64/295 (21%)
Query: 1936 WGRPQGLGRGCHRN---CVTTTWKP-SCCPGHYGSECQACPGGP------------SSPC 1979
WG G C N C+ T P S C GS CP G S PC
Sbjct: 347 WG-----GTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPC 401
Query: 1980 SDRGVCMDG-MSGSGQCLCRSGFAGTAC----ELCAPGAFGPH-CQACRCTVHGRCDEGL 2033
C ++GS CLC+ G++G C + C GP C+ HG
Sbjct: 402 HGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCE------HGGSCLNT 455
Query: 2034 GGSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEAVC---RAGNSCECSLGYEGDGRVCT 2090
GS +C C G+TG RCE + + PC P + C A C C G E G++C
Sbjct: 456 PGSFNCLCPPGYTGSRCEA--DHNECLSQPCHPGSTCLDLLATFHCLCPPGLE--GQLCE 511
Query: 2091 VADLCQDGHGGCSEHANCSQVGTMVTCTCLPDYEG-----DGWSCRARNPCTDGHRGGCS 2145
V + + C HA+C + C CLP + G D CR+ +PC +G G C
Sbjct: 512 V-ETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRS-SPCANG--GQCQ 567
Query: 2146 EHANCLSTGLNTRRCECHAGYVGDGLQCLEESEPPVDRCLGQPPPCHSDAMCTDL 2200
+ C+C G+ +G +C E VD CL PC A C DL
Sbjct: 568 DQPGAF-------HCKCLPGF--EGPRCQTE----VDECLSD--PCPVGASCLDL 607
Score = 94.4 bits (233), Expect = 1e-18
Identities = 104/385 (27%), Positives = 137/385 (35%), Gaps = 85/385 (22%)
Query: 654 CSEEQHKIVAGSCVDCQALNTS------TCPPNSVKLDIFPKECVYIHDPT---GLNVLK 704
CSEE +G C++ + N S TCPP+ + P G V +
Sbjct: 726 CSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNR 785
Query: 705 KGCASYCNQTIMEQGCCKGFFGPDCTQC--PGGFSNPCYGKGNCSDGIQGNGACLCFPDY 762
G S C GF GP C P +PC + C D QG CLC Y
Sbjct: 786 PGTFSCL--------CAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGP-RCLCPTGY 836
Query: 763 KGIACH----ICSN-PNKHGEQCQED-----CGCVHG----LCDNRPGS----------- 797
G +C +C+ P C + C C+ G LC N P S
Sbjct: 837 TGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLC-NLPLSSCQKAALSQGI 895
Query: 798 --------GGVCQQGT------CAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQEGV 843
GG+C C PGF G C + + C ++ C A C++Q
Sbjct: 896 DVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCE----SRPCQNGATCMAQPSG 951
Query: 844 ARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSG---DGR 900
C+C G++G S S P C + C P G HC C G+ G +G
Sbjct: 952 YLCQCAPGYDGQNCSKELDACQSQP----CHNHGTCTPKP-GGFHCACPPGFVGLRCEGD 1006
Query: 901 VCVAIDE-CELDMRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCH 959
V +D+ C CH+ A Y C C G G + IDPC + C
Sbjct: 1007 VDECLDQPCHPTGTAACHSLANAFY-------CQCLPGHTGQWCEVE-IDPCHSQP--CF 1056
Query: 960 GLATCRAVGGGQR--VCTCPPGFGG 982
TC A G +C CP GF G
Sbjct: 1057 HGGTCEATAGSPLGFICHCPKGFEG 1081
Score = 92.0 bits (227), Expect = 7e-18
Identities = 107/408 (26%), Positives = 142/408 (34%), Gaps = 66/408 (16%)
Query: 1865 EPPGLGARCDHFETRPLRLNTCSICGLEPPCPEGSQEQGSPEACWRFYPKFWTSPPLHSL 1924
+P G C T P + C PC G SP + T PP H+
Sbjct: 709 QPSGYNCTCPTGYTGPTCSEEMTACH-SGPCLNGGSCNPSPGGY------YCTCPPSHT- 760
Query: 1925 GLRSVWVHPSLWGRPQGLGRGCHRNCVTTTWKPSCCPGHYGSECQAC--PGGPSSPCSDR 1982
G + P G C T+ C G G C+ P SPC +R
Sbjct: 761 GPQCQTSTDYCVSAPCFNGGTCVNR--PGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNR 818
Query: 1983 GVCMDGMSGSGQCLCRSGFAGTACELCAPGAFGPHCQACRCTVHGRCDEGLGGSGSCFCD 2042
C D G +CLC +G+ G +C+ C C + C + G S C C
Sbjct: 819 ATCQDSPQGP-RCLCPTGYTGGSCQTLMD-----LCAQKPCPRNSHCLQ-TGPSFHCLCL 871
Query: 2043 EGWTGPRCEVQLEL--QPVCTPPCAPEAVCRAGNSC---------ECSLGYEGDGRVCTV 2091
+GWTGP C + L + + ++C G C C G++G
Sbjct: 872 QGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGS------ 925
Query: 2092 ADLCQDGHGGCSEH-----ANCSQVGTMVTCTCLPDYEGDGWSCRARNPCTDGHRGGCSE 2146
LCQD C A C + C C P Y+G S + + C C
Sbjct: 926 --LCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCS-KELDAC---QSQPCHN 979
Query: 2147 HANCLSTGLNTRRCECHAGYVGDGLQCLEESEPPVDRCLGQPPPCH--SDAMCTDLHFQE 2204
H C + C C G+V GL+C E VD CL Q PCH A C L
Sbjct: 980 HGTC-TPKPGGFHCACPPGFV--GLRC----EGDVDECLDQ--PCHPTGTAACHSL---- 1026
Query: 2205 KRAGVFHLQATSGPYGLNFSEAEA-ACEAQGAVLASFPQLSAAQQLGF 2251
A F+ Q G G + E E C +Q + +A LGF
Sbjct: 1027 --ANAFYCQCLPGHTG-QWCEVEIDPCHSQPCFHGGTCEATAGSPLGF 1071
Score = 91.7 bits (226), Expect = 9e-18
Identities = 79/252 (31%), Positives = 100/252 (39%), Gaps = 34/252 (13%)
Query: 737 SNPCYGKGNCSDG-IQGNGACLCFPDYKGIACHICSNPNKHGEQC----QEDCGCVH-GL 790
S PC+G CS + G+ CLC P Y G CH + ++C Q C H G
Sbjct: 398 SQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCH------QDLDECLMAQQGPSPCEHGGS 451
Query: 791 CDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLD 850
C N PGS C PG++G C +C L+Q CH + C+ C C
Sbjct: 452 CLNTPGSFNC----LCPPGYTGSRCEADHNEC----LSQPCHPGSTCLDLLATFHCLCPP 503
Query: 851 GFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGRVCVAIDECEL 910
G EG + S P C +A+C L C C G+SG R IDEC
Sbjct: 504 GLEGQLCEVETNECASAP----CLNHADC-HDLLNGFQCICLPGFSGT-RCEEDIDECR- 556
Query: 911 DMRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRAVGGG 970
C C PG C C GF G Q + +D C + C A+C + G
Sbjct: 557 --SSPCANGGQCQ-DQPGAFHCKCLPGFEGPRCQ-TEVDECL--SDPCPVGASCLDLPGA 610
Query: 971 QRVCTCPPGFGG 982
C CP GF G
Sbjct: 611 -FFCLCPSGFTG 621
Score = 90.9 bits (224), Expect = 1e-17
Identities = 71/244 (29%), Positives = 91/244 (37%), Gaps = 28/244 (11%)
Query: 100 CCPGYWGSRCHECPGGAET-PCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGP 158
C PG+ G C P + C GTC DG+D TC+C E + G C E D
Sbjct: 264 CPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTY-TCLCPETWTGWDCSEDVDEC---- 318
Query: 159 DCQSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQELPVCQELRCPQNTQC--SAEAPS 216
+ Q C +G G C+C +G+ G C++ L C C + C + S
Sbjct: 319 ETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFS 378
Query: 217 CRCLPGYTQQGSECRAPNPCWPSPCSLLAQCSVSP-KGQAQCHCPENYHG-------DGM 268
C C PG T G C + C PC AQCS +P G C C Y G D
Sbjct: 379 CLCPPGRT--GLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDEC 436
Query: 269 VCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPGLVSINSNASAGCFAFCSPFSCDR 328
+ + P GG N+ PG C C PG A C C
Sbjct: 437 LMAQQGPSPCEHGGSCLNT-------PGSFNCLCPPGYTGSRCEADHN---ECLSQPCHP 486
Query: 329 SATC 332
+TC
Sbjct: 487 GSTC 490
Score = 90.5 bits (223), Expect = 2e-17
Identities = 89/353 (25%), Positives = 122/353 (34%), Gaps = 58/353 (16%)
Query: 32 CDVKTTFVTHVPCTSCAAIK------KQTCPSGWLRELPDQITQDCRYEVQLGGSMVSMS 85
C+V+T PC + A + C G+ ++ +CR G
Sbjct: 510 CEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQ 569
Query: 86 GCRRKCRKQVVQKACCPGYWGSRCH-ECPGGAETPCNGHGTCLDGMDRNGTCVCQENFRG 144
C+ C PG+ G RC E PC +CLD + C+C F G
Sbjct: 570 PGAFHCK-------CLPGFEGPRCQTEVDECLSDPCPVGASCLD-LPGAFFCLCPSGFTG 621
Query: 145 SACQE-------CQDPNRFGPDCQSVCSCV-------------HGVCNHGPRGDGSCLCF 184
C+ CQ P + D + +C+ + C+HG SC+C
Sbjct: 622 QLCEVPLCAPNLCQ-PKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCD 680
Query: 185 AGYTGPHCDQELPVCQELRCPQNTQCSAEAP--SCRCLPGYTQQGSEC-RAPNPCWPSPC 241
G+TGP C+ EL C C C + +C C GYT G C C PC
Sbjct: 681 VGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYT--GPTCSEEMTACHSGPC 738
Query: 242 SLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPS----NSTLCVYQKPGQ 297
C+ SP G C CP ++ G C + C S N CV +PG
Sbjct: 739 LNGGSCNPSPGGY-YCTCPPSHTG--------PQCQTSTDYCVSAPCFNGGTCV-NRPGT 788
Query: 298 AFCTCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVTADGKTSCVCRESEVG 350
C C G C+ C ATCQ + G C+C G
Sbjct: 789 FSCLCAMGFQ--GPRCEGKLRPSCADSPCRNRATCQDSPQG-PRCLCPTGYTG 838
Score = 89.4 bits (220), Expect = 4e-17
Identities = 85/280 (30%), Positives = 110/280 (39%), Gaps = 53/280 (18%)
Query: 720 CCKGFFGPDCTQCPGG-FSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGE 778
C GF GPDC P S+ C G C DG+ CLC + G C ++ +
Sbjct: 264 CPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLD-TYTCLCPETWTGWDC------SEDVD 316
Query: 779 QCQEDCGCVHGLCDNRPGSGGVCQQG------TCAPGFSGRFCNESMGDCGPTGLAQHCH 832
+C E G H C N GG CQ C G+ G C E++ DC +A C
Sbjct: 317 EC-ETQGPPH--CRN----GGTCQNSAGSFHCVCVSGWGGTSCEENLDDC----IAATCA 365
Query: 833 LHARCVSQEGVARCRCLDGFEGDGFSCTPSNPC-SHPDRGGCSENAECVPGSL-GTHHCT 890
+ C+ + G C C G G C + C S P C +A+C L G+ C
Sbjct: 366 PGSTCIDRVGSFSCLCPPG--RTGLLCHLEDMCLSQP----CHGDAQCSTNPLTGSTLCL 419
Query: 891 CHKGWSGDGRVC-VAIDECELDMRG--GCHTDALCSYVGPGQSRCTCKLGFAG-----DG 942
C G+SG C +DEC + +G C C PG C C G+ G D
Sbjct: 420 CQPGYSGP--TCHQDLDECLMAQQGPSPCEHGGSCLNT-PGSFNCLCPPGYTGSRCEADH 476
Query: 943 YQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGFGG 982
+C PC G+ LAT C CPPG G
Sbjct: 477 NECLS-QPCHPGSTCLDLLATFH--------CLCPPGLEG 507
Score = 87.4 bits (215), Expect = 2e-16
Identities = 85/270 (31%), Positives = 106/270 (39%), Gaps = 52/270 (19%)
Query: 1320 CCPGFFGTLCEPCPGGLGGV-CSGHGQCQDRFLGSGECHCHEGFHGTACEV-CELGRYGP 1377
C PG G LCE C H C D L +C C GF GT CE + R P
Sbjct: 501 CPPGLEGQLCEVETNECASAPCLNHADCHD-LLNGFQCICLPGFSGTRCEEDIDECRSSP 559
Query: 1378 NCTGVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQC-PRKCDPNANCVQDSAG 1436
G G CQ+ G C C G++G RC ++ +C C A+C+ D G
Sbjct: 560 CANG------GQCQD-QPGAFHCKCLPGFEGPRCQTEV--DECLSDPCPVGASCL-DLPG 609
Query: 1437 ASTCACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQ 1496
A C C +G++G EV CA C P C K + C C DG G
Sbjct: 610 AFFCLCPSGFTGQ---LCEVPLCAPNL--CQPKQIC-KDQKDKANCLCPDGSPG---CAP 660
Query: 1497 EINSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGC--SPY 1554
++C HHG C Q+ SC C G++G C GGC +P
Sbjct: 661 PEDNCTCHHGHC-----------QRSSCVCDVGWTG---------PECEAELGGCISAPC 700
Query: 1555 A---TCKSTGDGQRTCTCDTAHTVGDGLTC 1581
A TC G CTC T +T G TC
Sbjct: 701 AHGGTCYPQPSGY-NCTCPTGYT---GPTC 726
Score = 87.0 bits (214), Expect = 2e-16
Identities = 93/363 (25%), Positives = 118/363 (32%), Gaps = 121/363 (33%)
Query: 720 CCKGFFGPDCTQ------CPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHI---- 769
C G+ GP C Q +PC G+C + G+ CLC P Y G C
Sbjct: 420 CQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLN-TPGSFNCLCPPGYTGSRCEADHNE 478
Query: 770 -CSNPNKHGEQCQEDCGCVHGLCDNRPG-SGGVCQQGT---------------------- 805
S P G C + H LC PG G +C+ T
Sbjct: 479 CLSQPCHPGSTCLDLLATFHCLCP--PGLEGQLCEVETNECASAPCLNHADCHDLLNGFQ 536
Query: 806 --CAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEG--------- 854
C PGFSG C E + +C + C +C Q G C+CL GFEG
Sbjct: 537 CICLPGFSGTRCEEDIDECR----SSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDE 592
Query: 855 ------------------------DGFS-------------CTPSNPC-SHPDRGGC--- 873
GF+ C P C D+ C
Sbjct: 593 CLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCP 652
Query: 874 ---------SENAECVPGSLGTHHCTCHKGWSGDGRVCVAIDECELDMRGGCHTDALCSY 924
+N C G C C GW+G ECE ++ GGC A C++
Sbjct: 653 DGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTG--------PECEAEL-GGC-ISAPCAH 702
Query: 925 VG-----PGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPG 979
G P CTC G+ G CS + +G C +C GG CTCPP
Sbjct: 703 GGTCYPQPSGYNCTCPTGYTGP--TCSE-EMTACHSGPCLNGGSCNPSPGGY-YCTCPPS 758
Query: 980 FGG 982
G
Sbjct: 759 HTG 761
Score = 85.9 bits (211), Expect = 5e-16
Identities = 75/261 (28%), Positives = 97/261 (37%), Gaps = 42/261 (16%)
Query: 1326 GTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEV------CELGRYGPNC 1379
G+ EPC G G C LG G C C GF G C+ +L + G +C
Sbjct: 29 GSFPEPCANG--------GTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSC 80
Query: 1380 TGVCDCAHGL--CQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGA 1437
+ GL L C C G+ G RC K+ P P C C ++G
Sbjct: 81 QALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGR 140
Query: 1438 STCACAAGYSGNGI----FCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGE 1493
C+C G++G FCS +PC +G C P Q C C G+ +G
Sbjct: 141 PQCSCMPGWTGEQCQLRDFCS-ANPCVNG-------GVCLATYP-QIQCHCPPGF--EGH 189
Query: 1494 LCQ-EINSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCEL-LDPCSKNNGGC 1551
C+ ++N C G C C T C C G G CEL PC GC
Sbjct: 190 ACERDVNECFQDPGPCPKGTSCHNT-LGSFQCLCPVGQEGP---RCELRAGPCPPR--GC 243
Query: 1552 SPYATCKSTGDGQRT---CTC 1569
S TC+ + T C C
Sbjct: 244 SNGGTCQLMPEKDSTFHLCLC 264
Score = 85.9 bits (211), Expect = 5e-16
Identities = 94/340 (27%), Positives = 117/340 (34%), Gaps = 96/340 (28%)
Query: 1939 PQGLGRGCHRNCVTTTWKPSCCPGHYGSECQACPGGPSSP--CSDRGVCMDGMSGSGQCL 1996
P LG + +T ++ +C PG G CQA P P CS RG C SG QC
Sbjct: 85 PAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCS 144
Query: 1997 CRSGFAGTACEL-------------------------CAPGAFGPHCQACRCTVH----- 2026
C G+ G C+L C PG G AC V+
Sbjct: 145 CMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEG---HACERDVNECFQD 201
Query: 2027 -GRCDEGLG-----GSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEAVCRAGNSCECSL 2080
G C +G GS C C G GPRCE++ PC P C G +C+
Sbjct: 202 PGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELR-------AGPCPPRG-CSNGGTCQLMP 253
Query: 2081 GYEGDGRVCT-----VADLCQDGHGGCSEHANCSQVGT----MVTCTCLPDYEGDGWSC- 2130
+ +C + C+ C H C GT + T TCL GW C
Sbjct: 254 EKDSTFHLCLCPPGFIGPDCEVNPDNCVSH-QCQNGGTCQDGLDTYTCLCPETWTGWDCS 312
Query: 2131 ------------RARNPCTDGHRGGCSEHANCLSTGLNTRRCE-----CHAGYVGDGLQC 2173
RN T + G S H C+S G CE C A G C
Sbjct: 313 EDVDECETQGPPHCRNGGTCQNSAG-SFHCVCVS-GWGGTSCEENLDDCIAATCAPGSTC 370
Query: 2174 LEESE------PP---------VDRCLGQPPPCHSDAMCT 2198
++ PP D CL Q PCH DA C+
Sbjct: 371 IDRVGSFSCLCPPGRTGLLCHLEDMCLSQ--PCHGDAQCS 408
Score = 85.1 bits (209), Expect = 8e-16
Identities = 111/452 (24%), Positives = 140/452 (30%), Gaps = 134/452 (29%)
Query: 1973 GGPSSPCSDRGVCMDGMSGSGQCLCRSGFAGTACEL------------------------ 2008
G PC++ G C+ G G C C GF G C+
Sbjct: 29 GSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPL 88
Query: 2009 ----------------CAPGAFGPHCQA--------CRCTVHGRCDEGLGGSGSCFCDEG 2044
C PG G CQA C+ GRC G C C G
Sbjct: 89 GLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPG 148
Query: 2045 WTGPRCEVQLELQPVCTP-PCAPEAVCRAGN---SCECSLGYEGDGRVCTVADLCQDGHG 2100
WTG +C +L+ C+ PC VC A C C G+EG V + QD G
Sbjct: 149 WTGEQC----QLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQD-PG 203
Query: 2101 GCSEHANCSQVGTMVTCTCLPDYEGDGWSCRARNPCTDGHRGGCSEHANCL---STGLNT 2157
C + +C C C EG RA PC GCS C
Sbjct: 204 PCPKGTSCHNTLGSFQCLCPVGQEGPRCELRA-GPCPP---RGCSNGGTCQLMPEKDSTF 259
Query: 2158 RRCECHAGYVG----------------------DGLQ-----CLE-----ESEPPVDRCL 2185
C C G++G DGL C E + VD C
Sbjct: 260 HLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECE 319
Query: 2186 GQ-PPPCHSDAMCTDLHFQEKRAGVFHLQATSGPYGLNFSEAEAACEAQGAVLASFPQLS 2244
Q PP C + C + AG FH SG G + E C A P +
Sbjct: 320 TQGPPHCRNGGTC------QNSAGSFHCVCVSGWGGTSCEENLDDCIAATCA----PGST 369
Query: 2245 AAQQLGFHLCLMGWLANGSTAHPVVFPVADCGNGRVGIVSLGARKNLSE--RWDAYCFR- 2301
++G CL C GR G++ LS+ DA C
Sbjct: 370 CIDRVGSFSCL-------------------CPPGRTGLLCHLEDMCLSQPCHGDAQCSTN 410
Query: 2302 --VQDVACRCRNGFVGDGISTCNGKLLDVLAA 2331
C C+ G+ G TC+ L + L A
Sbjct: 411 PLTGSTLCLCQPGYSG---PTCHQDLDECLMA 439
Score = 84.7 bits (208), Expect = 1e-15
Identities = 86/311 (27%), Positives = 114/311 (36%), Gaps = 67/311 (21%)
Query: 720 CCKGFFGPDCTQCPGG-FSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGE 778
C G+ GP+C GG S PC G C G C C Y G C ++
Sbjct: 679 CDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYN-CTCPTGYTGPTC------SEEMT 731
Query: 779 QCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCV 838
C G C+ PG G C TC P +G C S C ++ C CV
Sbjct: 732 ACHSGPCLNGGSCNPSPG-GYYC---TCPPSHTGPQCQTSTDYC----VSAPCFNGGTCV 783
Query: 839 SQEGVARCRCLDGFEGDGF------SC-------------TPSNP---CSHPDRGG---- 872
++ G C C GF+G SC +P P C GG
Sbjct: 784 NRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQT 843
Query: 873 ---------CSENAECVPGSLGTHHCTCHKGWSGDGRVC-VAIDECE-------LDMRGG 915
C N+ C+ + HC C +GW+G +C + + C+ +D+
Sbjct: 844 LMDLCAQKPCPRNSHCLQTG-PSFHCLCLQGWTGP--LCNLPLSSCQKAALSQGIDVSSL 900
Query: 916 CHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCT 975
CH LC GP C C GF G Q ++PC + C ATC A G +C
Sbjct: 901 CHNGGLCVDSGPSYF-CHCPPGFQGSLCQ-DHVNPCE--SRPCQNGATCMAQPSGY-LCQ 955
Query: 976 CPPGFGGDGFS 986
C PG+ G S
Sbjct: 956 CAPGYDGQNCS 966
Score = 81.6 bits (200), Expect = 9e-15
Identities = 91/338 (26%), Positives = 122/338 (36%), Gaps = 60/338 (17%)
Query: 1281 CTQGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKKIQVPDCCPGFFGTLCEPCPGGLGGVC 1340
C G P +C G C C P+C G + PC G G C
Sbjct: 651 CPDGSPGCAPPEDNCTCHHGHCQRSSC--VCDVGWTGPECEAELGGCISAPCAHG--GTC 706
Query: 1341 ----SGHG-QCQDRFLGSG------ECHCHEGFHGTACEVCELGRY--------GPNCTG 1381
SG+ C + G CH +G +C G Y GP C
Sbjct: 707 YPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQT 766
Query: 1382 VCD-CAHGLCQEG-----LQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSA 1435
D C C G G SC+C +G+QG RC+ K+ C A C QDS
Sbjct: 767 STDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATC-QDSP 825
Query: 1436 GASTCACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMG----- 1490
C C GY+G G + +D CA C +++C + P C C G+ G
Sbjct: 826 QGPRCLCPTGYTG-GSCQTLMDLCA--QKPCPRNSHCLQTGPSFH-CLCLQGWTGPLCNL 881
Query: 1491 ------DGELCQEIN-SCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLDP 1543
L Q I+ S L H+GG C+ +GP C C G+ G + + ++P
Sbjct: 882 PLSSCQKAALSQGIDVSSLCHNGGL-----CVDSGPSYF-CHCPPGFQGSLCQ--DHVNP 933
Query: 1544 CSKNNGGCSPYATCKSTGDGQRTCTCDTAHTVGDGLTC 1581
C C ATC + G C C + DG C
Sbjct: 934 CESR--PCQNGATCMAQPSGY-LCQCAPGY---DGQNC 965
Score = 80.9 bits (198), Expect = 2e-14
Identities = 94/320 (29%), Positives = 122/320 (38%), Gaps = 51/320 (15%)
Query: 1281 CTQGFQ--LQDTPRKSCVYRSGFSFSRGCSYTCAKKIQVPDCCPGFFGTLCEPCPGGLGG 1338
C QG+ L + P SC ++ S S C D P +F C PG G
Sbjct: 870 CLQGWTGPLCNLPLSSC-QKAALSQGIDVSSLCHNGGLCVDSGPSYF---CHCPPGFQGS 925
Query: 1339 VCSGH-GQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCTGVCDCA-------HGLC 1390
+C H C+ R +G C G C+ C G G NC+ D HG C
Sbjct: 926 LCQDHVNPCESRPCQNGAT-CMAQPSGYLCQ-CAPGYDGQNCSKELDACQSQPCHNHGTC 983
Query: 1391 QEGLQGDGSCVCNVGWQGLRCDQKITSPQC-PRKCDPNANCVQDS-AGASTCACAAGYSG 1448
G C C G+ GLRC+ + +C + C P S A A C C G++G
Sbjct: 984 TPK-PGGFHCACPPGFVGLRCEGDV--DECLDQPCHPTGTAACHSLANAFYCQCLPGHTG 1040
Query: 1449 NGIFCS-EVDPCAHG----HGGCSPHANCTKVAPGQRTCTCQDGYMGDGELC-QEINSCL 1502
+C E+DPC H HGG T +P C C G+ +G C SC
Sbjct: 1041 Q--WCEVEIDPC-HSQPCFHGGT---CEATAGSPLGFICHCPKGF--EGPTCSHRAPSCG 1092
Query: 1503 IHHGGCHIHAECIPTGPQ--QVSCSCREGYSGDGIRT------CELLDPCSKNNGGCSPY 1554
HH CH C+P+ C+C GY G T C PC NG CS
Sbjct: 1093 FHH--CHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPC-LYNGSCS-- 1147
Query: 1555 ATCKSTGDGQRTCTCDTAHT 1574
++TG G C H+
Sbjct: 1148 ---ETTGLGGPGFRCSCPHS 1164
Score = 80.1 bits (196), Expect = 3e-14
Identities = 87/352 (24%), Positives = 117/352 (33%), Gaps = 71/352 (20%)
Query: 44 CTSCAAIKKQTCPSGWLRELPDQITQDCRYEVQLGGSMVSMSGCRRKCRKQVVQKACC-- 101
C + A C SGW ++ DC GS C +V +C
Sbjct: 332 CQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGST---------CIDRVGSFSCLCP 382
Query: 102 PGYWGSRCHECPGGAETPCNGHGTCLDGMDRNGT-CVCQENFRGSACQECQDPNRFGPDC 160
PG G CH PC+G C T C+CQ + G C + D
Sbjct: 383 PGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQ-- 440
Query: 161 QSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQELPVCQELRCPQNTQC---------- 210
Q C HG G +CLC GYTG C+ + C C + C
Sbjct: 441 QGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCL 500
Query: 211 ----------------SAEAP--------------SCRCLPGYTQQGSECRAP-NPCWPS 239
A AP C CLPG++ G+ C + C S
Sbjct: 501 CPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFS--GTRCEEDIDECRSS 558
Query: 240 PCSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPK-DPCTDNLGGCPSNSTLCVYQKPGQA 298
PC+ QC P G C C + +G C + D C + CP ++ C+ PG
Sbjct: 559 PCANGGQCQDQP-GAFHCKCLPGF--EGPRCQTEVDECLSD--PCPVGAS-CL-DLPGAF 611
Query: 299 FCTCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVTADGKTSCVCRESEVG 350
FC C G C+P C C+ D K +C+C + G
Sbjct: 612 FCLCPSGFTGQLCEV-----PLCAPNLCQPKQICKDQKD-KANCLCPDGSPG 657
Score = 79.3 bits (194), Expect = 4e-14
Identities = 89/341 (26%), Positives = 110/341 (32%), Gaps = 51/341 (14%)
Query: 10 LCLLAF----CLAGFSFVRGQVLFKGCDVKTTFVTHVPCTSCAAIKKQTCPSGWLRELPD 65
LCL + C S + L +G DV + C CP G+ L
Sbjct: 869 LCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQ 928
Query: 66 QITQDCRYEVQLGGSMVSMSGCRRKCRKQVVQKACCPGYWGSRCH-ECPGGAETPCNGHG 124
C G+ C+ C PGY G C E PC+ HG
Sbjct: 929 DHVNPCESRPCQNGATCMAQPSGYLCQ-------CAPGYDGQNCSKELDACQSQPCHNHG 981
Query: 125 TCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHGVCNHGPRGDGSCLCF 184
TC C C F G C+ D P + + H + N C C
Sbjct: 982 TCTP-KPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAF-----YCQCL 1035
Query: 185 AGYTGPHCDQELPVCQELRCPQNTQCSAEAPS-----CRCLPGYTQQGSECRAPNPCWPS 239
G+TG C+ E+ C C C A A S C C G+ RAP+ C
Sbjct: 1036 PGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPS-CGFH 1094
Query: 240 PCSLLAQCSVSPKG--QAQCHCPENYHGDGMV-------CLPKDPC--------TDNLGG 282
C C SPK +C C Y G + C P PC T LGG
Sbjct: 1095 HCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGG 1154
Query: 283 ------CPSNSTLCVYQKPGQAFCTCRPGLVSINSNASAGC 317
CP +S QKPG C R G + AGC
Sbjct: 1155 PGFRCSCPHSSPGPRCQKPGAKGCEGRSG----DGACDAGC 1191
Score = 78.6 bits (192), Expect = 8e-14
Identities = 72/262 (27%), Positives = 100/262 (38%), Gaps = 33/262 (12%)
Query: 734 GGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQCQEDCGCVHGL--- 790
G F PC G C G G C C P + G C +P ++ + CQ C L
Sbjct: 29 GSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQF-PDPCQNAQLCQNGGSCQALLPAP 87
Query: 791 --CDNRPGSGGVCQQGTCAPGFSGRFCNESMGD-CGPTGLAQHCHLHARC-VSQEGVARC 846
+ P TC PGF+G C + D C P+ C RC + G +C
Sbjct: 88 LGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPS----FCSKRGRCHIQASGRPQC 143
Query: 847 RCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGRVCVA-I 905
C+ G+ G+ C + CS C C+ + C C G+ +G C +
Sbjct: 144 SCMPGWTGE--QCQLRDFCS---ANPCVNGGVCL-ATYPQIQCHCPPGF--EGHACERDV 195
Query: 906 DECELDMRGGCHTDALCSYVGPGQSRCTCKLGFAGD--GYQCSPIDPCRAGNGGCHGLAT 963
+EC D G C C + G +C C +G G + P P NGG T
Sbjct: 196 NECFQD-PGPCPKGTSC-HNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGG-----T 248
Query: 964 CRAV---GGGQRVCTCPPGFGG 982
C+ + +C CPPGF G
Sbjct: 249 CQLMPEKDSTFHLCLCPPGFIG 270
Score = 78.2 bits (191), Expect = 1e-13
Identities = 101/379 (26%), Positives = 129/379 (34%), Gaps = 91/379 (24%)
Query: 665 SCVDCQALNTSTCPPNSVKLDIFPKECVYIHDPTG--LNVLKKGCA-------SYCNQT- 714
SC D N +TC + C+ TG L CA S+C QT
Sbjct: 809 SCADSPCRNRATCQDSPQG-----PRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTG 863
Query: 715 -IMEQGCCKGFFGPDC----TQCPGG-------FSNPCYGKGNCSDGIQGNGACLCFPDY 762
C +G+ GP C + C S+ C+ G C D + C C P +
Sbjct: 864 PSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDS-GPSYFCHCPPGF 922
Query: 763 KGIACHICSNPNKHGEQCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDC 822
+G C NP + CQ C+ SG +CQ CAPG+ G+ C++ + C
Sbjct: 923 QGSLCQDHVNPCE-SRPCQNGATCM------AQPSGYLCQ---CAPGYDGQNCSKELDAC 972
Query: 823 GPTGLAQHCHLHARCVSQEGVARCRCLDGF-----EGDGFSCTPSNPCSHPDRGGCSENA 877
+Q CH H C + G C C GF EGD C PC C A
Sbjct: 973 Q----SQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECL-DQPCHPTGTAACHSLA 1027
Query: 878 -----ECVPGSLG----THHCTCHKGWSGDGRVCVA--------IDECELDMRG------ 914
+C+PG G CH G C A I C G
Sbjct: 1028 NAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHR 1087
Query: 915 -------GCHTDALC-SYVGPG-QSRCTCKLGFAGDG-------YQCSPIDPCRAGNGGC 958
CH LC PG RC C G+ G C P PC NG C
Sbjct: 1088 APSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPC-LYNGSC 1146
Query: 959 HGLATCRAVGGGQRVCTCP 977
+ +GG C+CP
Sbjct: 1147 ---SETTGLGGPGFRCSCP 1162
Score = 77.4 bits (189), Expect = 2e-13
Identities = 75/265 (28%), Positives = 91/265 (34%), Gaps = 24/265 (9%)
Query: 720 CCKGFFGPDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQ 779
C G+ G C +NPC G C C C P ++G AC + +
Sbjct: 145 CMPGWTGEQCQLRDFCSANPCVNGGVCL-ATYPQIQCHCPPGFEGHAC------ERDVNE 197
Query: 780 CQEDCG-CVHGL-CDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARC 837
C +D G C G C N GS Q C G G C G C P G +
Sbjct: 198 CFQDPGPCPKGTSCHNTLGS----FQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMP 253
Query: 838 VSQEGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSG 897
C C GF G P N SH C C G L T+ C C + W+G
Sbjct: 254 EKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQ----CQNGGTCQDG-LDTYTCLCPETWTG 308
Query: 898 DGRVCVAIDECELDMRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGG 957
+DECE C C G C C G+ G + +D C A
Sbjct: 309 -WDCSEDVDECETQGPPHCRNGGTCQN-SAGSFHCVCVSGWGGTSCE-ENLDDCIAAT-- 363
Query: 958 CHGLATCRAVGGGQRVCTCPPGFGG 982
C +TC G C CPPG G
Sbjct: 364 CAPGSTC-IDRVGSFSCLCPPGRTG 387
Score = 73.9 bits (180), Expect = 2e-12
Identities = 90/347 (25%), Positives = 110/347 (31%), Gaps = 93/347 (26%)
Query: 720 CCKGFFGPDCTQ-----CPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHI---CS 771
C GF G C CP F C +G C G C C P + G C + CS
Sbjct: 105 CLPGFTGERCQAKLEDPCPPSF---CSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFCS 161
Query: 772 -NPNKHGEQC-----QEDCGCVHGL-----------CDNRPGSGGVCQQGT--------- 805
NP +G C Q C C G C PG C +GT
Sbjct: 162 ANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGP---CPKGTSCHNTLGSF 218
Query: 806 ---CAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGDGFSCTPS 862
C G G C G C P G + C C GF G P
Sbjct: 219 QCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPD 278
Query: 863 NPCSHPDRGG----------------------CSENAE---------CVPG-----SLGT 886
N SH + G CSE+ + C G S G+
Sbjct: 279 NCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGS 338
Query: 887 HHCTCHKGWSGDGRVCVA-IDECELDMRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQC 945
HC C GW G C +D+C + C + C G C C G G C
Sbjct: 339 FHCVCVSGWGGTS--CEENLDDC---IAATCAPGSTC-IDRVGSFSCLCPPG--RTGLLC 390
Query: 946 SPIDPCRAGNGGCHGLATCRAVG-GGQRVCTCPPGFGGDGFSCYGDI 991
D C + CHG A C G +C C PG+ G +C+ D+
Sbjct: 391 HLEDMCL--SQPCHGDAQCSTNPLTGSTLCLCQPGYSGP--TCHQDL 433
Score = 66.6 bits (161), Expect = 3e-10
Identities = 78/331 (23%), Positives = 107/331 (32%), Gaps = 80/331 (24%)
Query: 97 QKACCPGYWGSRCHECPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQ----EC-Q 151
Q +C PG+ G +C + PC G CL + C C F G AC+ EC Q
Sbjct: 142 QCSCMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQI-QCHCPPGFEGHACERDVNECFQ 200
Query: 152 DPN----------------------RFGPDCQ---SVC---SCVHG-VCNHGPRGDGS-- 180
DP + GP C+ C C +G C P D +
Sbjct: 201 DPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFH 260
Query: 181 -CLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQGSECRAP-NPC-- 236
CLC G+ GP C+ C +C C + CL T G +C + C
Sbjct: 261 LCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECET 320
Query: 237 -WPSPCSLLAQCSVSPKGQAQCHCPENYHGD----------GMVCLPKDPCTDNLGG--- 282
P C C S G C C + G C P C D +G
Sbjct: 321 QGPPHCRNGGTCQNS-AGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSC 379
Query: 283 -CPSNST--------LCVYQK------------PGQAFCTCRPGL--VSINSNASAGCFA 319
CP T +C+ Q G C C+PG + + + A
Sbjct: 380 LCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMA 439
Query: 320 FCSPFSCDRSATCQVTADGKTSCVCRESEVG 350
P C+ +C + G +C+C G
Sbjct: 440 QQGPSPCEHGGSC-LNTPGSFNCLCPPGYTG 469
Score = 62.8 bits (151), Expect = 4e-09
Identities = 78/279 (27%), Positives = 95/279 (34%), Gaps = 78/279 (27%)
Query: 1959 CCPGHYGSECQA-CPGGPSSPCSDRGVCMDGMSGSGQ---CLCRSGFAGTACE------- 2007
C PGH G C+ S PC G C + +GS C C GF G C
Sbjct: 1034 CLPGHTGQWCEVEIDPCHSQPCFHGGTC-EATAGSPLGFICHCPKGFEGPTCSHRAPSCG 1092
Query: 2008 --------LCAP--------------GAFGPHC------QAC----RCTVHGRCDE--GL 2033
LC P G GP C + C C +G C E GL
Sbjct: 1093 FHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGL 1152
Query: 2034 GGSG-SCFCDEGWTGPRCEVQLELQPVCTPPCAPEAVCRAGNSCECSLGYEG-----DGR 2087
GG G C C GPRC+ P A R+G+ C G G DG
Sbjct: 1153 GGPGFRCSCPHSSPGPRCQ----------KPGAKGCEGRSGDGA-CDAGCSGPGGNWDGG 1201
Query: 2088 VCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPDYEG---DGWSCRARNPCTDGHRGGC 2144
C++ D GC H+ C + C D E DG+ C CT + C
Sbjct: 1202 DCSLG--VPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECLFDGYDCETPPACTPAYDQYC 1259
Query: 2145 SEH---ANCLSTGLNTRRCECHAGYVGDGLQCLEESEPP 2180
+H +C G NT C G+ DG C E P
Sbjct: 1260 HDHFHNGHC-EKGCNTAEC----GW--DGGDCRPEDGDP 1291
Score = 62.8 bits (151), Expect = 4e-09
Identities = 75/273 (27%), Positives = 96/273 (35%), Gaps = 72/273 (26%)
Query: 1320 CCPGFFGTLCE----PC---PGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCEL 1372
C PG G CE PC P GG C F+ CHC +GF G C
Sbjct: 1034 CLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFI----CHCPKGFEGPTC----- 1084
Query: 1373 GRYGPNCTGVCDCAH-GLCQEGLQG--DGSCVCNVGWQGLRCDQKITSPQCPRKCDPNAN 1429
P+C G C H GLC + C C G+ G C +P P+ C P +
Sbjct: 1085 SHRAPSC-GFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDC----LTPPAPKGCGPPSP 1139
Query: 1430 CVQDSAGASTCACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYM 1489
C+ + +C+ G G G CS C H SP C K PG + C +G
Sbjct: 1140 CLYN----GSCSETTGLGGPGFRCS----CPHS----SPGPRCQK--PGAKGC---EGRS 1182
Query: 1490 GDGELCQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLDPCSKNNG 1549
GDG +C CS G G + + DP
Sbjct: 1183 GDG-------AC-------------------DAGCSGPGGNWDGGDCSLGVPDPWK---- 1212
Query: 1550 GCSPYATC-KSTGDGQRTCTCDTAHTVGDGLTC 1581
GC ++ C DGQ CD+ + DG C
Sbjct: 1213 GCPSHSRCWLLFRDGQCHPQCDSEECLFDGYDC 1245
Score = 48.9 bits (115), Expect = 6e-05
Identities = 36/122 (29%), Positives = 48/122 (39%), Gaps = 15/122 (12%)
Query: 873 CSENAECVPGSLGTHHCTCHKGWSGDGRVCVAIDECE---LDMRGGCHTDALCSYVGPGQ 929
C+ C+ SLG C C G+ G+ C D C+ L GG L + +G
Sbjct: 35 CANGGTCLSLSLGQGTCQCAPGFLGE--TCQFPDPCQNAQLCQNGGSCQALLPAPLGLPS 92
Query: 930 SR--------CTCKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGFG 981
S CTC GF G+ Q DPC C C G+ C+C PG+
Sbjct: 93 SPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSF--CSKRGRCHIQASGRPQCSCMPGWT 150
Query: 982 GD 983
G+
Sbjct: 151 GE 152
Score = 48.9 bits (115), Expect = 6e-05
Identities = 56/194 (28%), Positives = 71/194 (36%), Gaps = 44/194 (22%)
Query: 720 CCKGFFGPDCTQCPG----GFSNPCYGKGNCSD--GIQGNG-ACLCFPDYKGIACHICSN 772
C G+ GPDC P G +PC G+CS+ G+ G G C C G C
Sbjct: 1116 CLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQ---K 1172
Query: 773 PNKHGEQCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDC--GPTGLAQH 830
P G C+ R G G C G SG N GDC G +
Sbjct: 1173 PGAKG-------------CEGRSGDGA------CDAGCSGPGGNWDGGDCSLGVPDPWKG 1213
Query: 831 CHLHARC--VSQEGVARCRCLDGFE--GDGFSCTPSNPCSHPDRGGCSE---NAECVPGS 883
C H+RC + ++G +C D E DG+ C C+ C + N C G
Sbjct: 1214 CPSHSRCWLLFRDGQCHPQC-DSEECLFDGYDCETPPACTPAYDQYCHDHFHNGHCEKG- 1271
Query: 884 LGTHHCTCHKGWSG 897
T C GW G
Sbjct: 1272 CNTAEC----GWDG 1281
Score = 47.4 bits (111), Expect = 2e-04
Identities = 33/126 (26%), Positives = 45/126 (35%), Gaps = 15/126 (11%)
Query: 237 WPSPCSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTD-----NLGGCPS--NSTL 289
+P PC+ C GQ C C + G+ C DPC + N G C + + L
Sbjct: 31 FPEPCANGGTCLSLSLGQGTCQCAPGFLGE--TCQFPDPCQNAQLCQNGGSCQALLPAPL 88
Query: 290 CVYQKPGQA----FCTCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVTADGKTSCVCR 345
+ P CTC PG A C P C + C + A G+ C C
Sbjct: 89 GLPSSPSPLTPSFLCTCLPGFTG--ERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCM 146
Query: 346 ESEVGD 351
G+
Sbjct: 147 PGWTGE 152
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 97.8 bits (242), Expect = 1e-19
Identities = 66/256 (25%), Positives = 96/256 (37%), Gaps = 31/256 (12%)
Query: 99 ACCPGYWGSRCHE----CPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPN 154
AC PG+ G C E CPG C G C+DG++ C C + G C E D
Sbjct: 244 ACLPGFTGQNCEENIDDCPGNN---CKNGGACVDGVNTYN-CRCPPEWTGQYCTEDVDEC 299
Query: 155 RFGPDCQSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEA 214
+ P+ +C +G H G +C+C G+TG C + + C C C
Sbjct: 300 QLMPN-----ACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRV 354
Query: 215 PSCRCLPGYTQQGSECRAPNPCWPSPCSLLAQCSVSP-KGQAQCHCPENYHGDGMVCLPK 273
S C + + G C + C +PC+ + C +P G+A C CP Y G
Sbjct: 355 ASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPA------ 408
Query: 274 DPCTDNLGGCPSNSTLCVY-----QKPGQAFCTCRPGLVSINSNASAGCFAFCSPFSCDR 328
C+ ++ C + C + G C C G C C
Sbjct: 409 --CSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVN---ECVSNPCQN 463
Query: 329 SATCQVTADGKTSCVC 344
ATC + G+ C+C
Sbjct: 464 DATC-LDQIGEFQCIC 478
Score = 92.8 bits (229), Expect = 4e-18
Identities = 86/309 (27%), Positives = 122/309 (39%), Gaps = 35/309 (11%)
Query: 1275 CTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRGC-SYTCAKKIQVPDCC--PGFFGTLC-- 1329
C R F L+ T +C S C S TC KI +C PG+ G++C
Sbjct: 618 CQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNI 677
Query: 1330 --EPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCTGVCDCAH 1387
+ C G C G C+D G C C EG+H C + E+ N C H
Sbjct: 678 NIDECAGN---PCHNGGTCEDGINGF-TCRCPEGYHDPTC-LSEVNECNSN-----PCVH 727
Query: 1388 GLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTCACAAGYS 1447
G C++ L G C C+ GW G CD I + +C N +D C C G+S
Sbjct: 728 GACRDSLNGY-KCDCDPGWSGTNCD--INNNECESNPCVNGGTCKDMTSGYVCTCREGFS 784
Query: 1448 GNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINSCLIHHGG 1507
G + ++ CA C C G + C C Y G C E+
Sbjct: 785 GPNC-QTNINECA--SNPCLNQGTCIDDVAGYK-CNCLLPY--TGATC-EVVLAPCAPSP 837
Query: 1508 CHIHAECIPTGP-QQVSCSCREGYSGDGIRTCEL-LDPCSKNNGGCSPYATCKSTGDGQR 1565
C EC + + SC C G+ G +TCE+ ++ C + C A+C++T G R
Sbjct: 838 CRNGGECRQSEDYESFSCVCPTGWQG---QTCEVDINECVLS--PCRHGASCQNTHGGYR 892
Query: 1566 TCTCDTAHT 1574
C C ++
Sbjct: 893 -CHCQAGYS 900
Score = 92.0 bits (227), Expect = 7e-18
Identities = 80/322 (24%), Positives = 117/322 (36%), Gaps = 60/322 (18%)
Query: 67 ITQDCRYEVQLGGSMVSMSGCRRKCRKQVVQKACCPGYWGSRCHECPGGAETPCNGHGTC 126
+T CR GG+ ++ KCR C PG+ G C + A PC G C
Sbjct: 107 LTNPCRN----GGTCDLLTLTEYKCR-------CPPGWSGKSCQQADPCASNPCANGGQC 155
Query: 127 LDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHGVCNHGPRGDGSCLCFAG 186
L + + C C +F G C+ QD N G Q C HG H G C+C A
Sbjct: 156 LP-FEASYICHCPPSFHGPTCR--QDVNECG---QKPGLCRHGGTCHNEVGSYRCVCRAT 209
Query: 187 YTGPHCDQELPVCQELRCPQNTQCSAEAP---SCRCLPGYTQQGSE-------------- 229
+TGP+C++ C C C C CLPG+T Q E
Sbjct: 210 HTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNG 269
Query: 230 -----------CRAPNPCWPSPCSL--LAQCSVSPKG-QAQCHCPENYHGDGMVCL---P 272
CR P P W + +C + P Q C + G VC+
Sbjct: 270 GACVDGVNTYNCRCP-PEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWT 328
Query: 273 KDPCTDNLGGCPSNSTL---CVYQKPGQAFCTCRPGLVSINSNASAGCFAFCSPFSCDRS 329
+ C++N+ C S + + + +C C G + + + C + +P C+
Sbjct: 329 GEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACIS--NP--CNEG 384
Query: 330 ATCQVT-ADGKTSCVCRESEVG 350
+ C +GK C C G
Sbjct: 385 SNCDTNPVNGKAICTCPSGYTG 406
Score = 91.7 bits (226), Expect = 9e-18
Identities = 90/304 (29%), Positives = 117/304 (38%), Gaps = 65/304 (21%)
Query: 717 EQGCCKGFFGPDCT----QCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIAC----- 767
E C G+ G C +C G NPC+ G C DGI G C C Y C
Sbjct: 663 ECACEPGYTGSMCNINIDECAG---NPCHNGGTCEDGING-FTCRCPEGYHDPTCLSEVN 718
Query: 768 HICSNPNKHGEQCQED-----CGCVHGL-----------CDNRP-GSGGVCQQ------G 804
SNP HG C++ C C G C++ P +GG C+
Sbjct: 719 ECNSNPCVHG-ACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVC 777
Query: 805 TCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGDGFS-----C 859
TC GFSG C ++ +C + C C+ +C CL + G C
Sbjct: 778 TCREGFSGPNCQTNINECA----SNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPC 833
Query: 860 TPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGRVC-VAIDECELDMRGGCHT 918
PS PC + SE+ E + C C GW G+ C V I+EC L C
Sbjct: 834 APS-PCRNGGECRQSEDYE-------SFSCVCPTGW--QGQTCEVDINECVL---SPCRH 880
Query: 919 DALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPP 978
A C G RC C+ G++G + + ID CR CH +C G C C P
Sbjct: 881 GASCQNTHGGY-RCHCQAGYSGRNCE-TDIDDCRP--NPCHNGGSC-TDGINTAFCDCLP 935
Query: 979 GFGG 982
GF G
Sbjct: 936 GFRG 939
Score = 90.9 bits (224), Expect = 1e-17
Identities = 83/311 (26%), Positives = 117/311 (37%), Gaps = 43/311 (13%)
Query: 55 CPSGWLRELPDQITQDCRYEVQLGGSMVSMSGCRRKCRKQVVQKACCPGYWGSRCH-ECP 113
CP+GW + + +C G+ + +C C GY G C +
Sbjct: 857 CPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCH-------CQAGYSGRNCETDID 909
Query: 114 GGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPD-CQSVCSCVHGVCN 172
PC+ G+C DG++ C C FRG+ C+E D N D C++ +C V +
Sbjct: 910 DCRPNPCHNGGSCTDGIN-TAFCDCLPGFRGTFCEE--DINECASDPCRNGANCTDCVDS 966
Query: 173 HGPRGDGSCLCFAGYTGPHCDQELPVCQELRCPQNTQC--SAEAPSCRCLPGYTQQGSEC 230
+ +C C AG++G HC+ P C E C C + +C C PG+T GS C
Sbjct: 967 Y------TCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFT--GSYC 1018
Query: 231 RAP-NPCWPSPCSLLAQCSVSPKGQAQCHCPENYHGDGMVCL----PKDPCTDNLGGCPS 285
+ N C PC C G +C CP+ Y G L PC N G C
Sbjct: 1019 QHDVNECDSQPCLHGGTCQ-DGCGSYRCTCPQGYTGPNCQNLVHWCDSSPC-KNGGKC-- 1074
Query: 286 NSTLCVYQKPGQAFCTCRPGLVSINSNA-SAGCFAFCSPFSCDRSATCQ-----VTADGK 339
+Q Q C C G + + S C D + CQ V A
Sbjct: 1075 ------WQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNT 1128
Query: 340 TSCVCRESEVG 350
C C+ G
Sbjct: 1129 HHCRCQAGYTG 1139
Score = 90.5 bits (223), Expect = 2e-17
Identities = 88/312 (28%), Positives = 110/312 (35%), Gaps = 81/312 (25%)
Query: 90 KCRKQVVQKAC-CP-GYWGSRCH----ECPGGAETPCNGHGTCLDGMDRNGTCVCQENFR 143
+C ++ + C CP G+ G C EC A TPC CLDG + TCVC E +
Sbjct: 504 RCLDKINEFQCECPTGFTGHLCQYDVDEC---ASTPCKNGAKCLDGPNTY-TCVCTEGYT 559
Query: 144 GSACQECQDPNRFGPDCQSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQELPVCQELR 203
G+ C+ D + PD SC GV +CLC GYTG HC+ + C
Sbjct: 560 GTHCEV--DIDECDPDPCHYGSCKDGVATF------TCLCRPGYTGHHCETNINECSSQP 611
Query: 204 CPQNTQCS--------------------------AEAP-------------SCRCLPGYT 224
C C A +P C C PGYT
Sbjct: 612 CRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYT 671
Query: 225 QQGSECRAP-NPCWPSPCSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKDP-CTDNLGG 282
GS C + C +PC C G C CPE YH DP C +
Sbjct: 672 --GSMCNINIDECAGNPCHNGGTCEDGING-FTCRCPEGYH---------DPTCLSEVNE 719
Query: 283 CPSNSTLCVYQKPGQAF----CTCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVTADG 338
C NS CV+ + C C PG N + + C C TC+ G
Sbjct: 720 C--NSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNN---ECESNPCVNGGTCKDMTSG 774
Query: 339 KTSCVCRESEVG 350
C CRE G
Sbjct: 775 YV-CTCREGFSG 785
Score = 90.1 bits (222), Expect = 2e-17
Identities = 109/410 (26%), Positives = 146/410 (35%), Gaps = 88/410 (21%)
Query: 1949 NCVTTTWKPSC-CP-GHYGSECQA-CPGGPSSPCSDRGVCMDGMSGSGQCLCRSGFAGTA 2005
NC +C CP G G C+ P S C + G C+DG++ S CLC GF G+
Sbjct: 959 NCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGIN-SFTCLCPPGFTGSY 1017
Query: 2006 CELCAPGAFGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPVC-TPPC 2064
C+ C + C G C +G G S C C +G+TGP C+ L C + PC
Sbjct: 1018 CQHDVN-----ECDSQPCLHGGTCQDGCG-SYRCTCPQGYTGPNCQ---NLVHWCDSSPC 1068
Query: 2065 APEAVCRAGNS---CECSLGYEG--------------DGRVCTVADLCQDGHGGCSEHAN 2107
C ++ CEC G+ G + VA LCQ HGG
Sbjct: 1069 KNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQ--HGGL----- 1121
Query: 2108 CSQVGTMVTCTCLPDYEG----DGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRCECH 2163
C G C C Y G D + +PC +G C+++ L C+C
Sbjct: 1122 CVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNG--ATCTDY-------LGGYSCKCV 1172
Query: 2164 AGYVGDGLQCLEESEPPVDRCLGQPPPCHSDAMCTDLHFQEKRAGVFHLQATSGPYG--- 2220
AGY G+ C EE +D CL PC + C DL + G G
Sbjct: 1173 AGY--HGVNCSEE----IDECLSH--PCQNGGTCLDL------PNTYKCSCPRGTQGVHC 1218
Query: 2221 -LNFSEAEAACEAQGAVLASFPQLSAAQQLGFHLCLMGWLANGSTAHPVVFPVADCGNGR 2279
+N + + F + Q+G + C P G
Sbjct: 1219 EINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSC--------------TCPPGFVGERC 1264
Query: 2280 VGIVSLGARKNLSERWDAYCF-RVQDVACRCRNGFVG----DGISTCNGK 2324
G V+ R C RV D C CR G G I+ C GK
Sbjct: 1265 EGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGK 1314
Score = 89.4 bits (220), Expect = 4e-17
Identities = 89/348 (25%), Positives = 123/348 (35%), Gaps = 99/348 (28%)
Query: 708 ASYCNQTI--MEQGCCKGFFGPDC----TQCPGGFSNPCYGKGNCSDGIQGNGACLCFPD 761
A C T+ E C +G+ GP C +C SNPC C D I G C+C P
Sbjct: 426 AGKCINTLGSFECQCLQGYTGPRCEIDVNEC---VSNPCQNDATCLDQI-GEFQCICMPG 481
Query: 762 YKGIAC-----------------------------------HIC--------SNPNKHGE 778
Y+G+ C H+C S P K+G
Sbjct: 482 YEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGA 541
Query: 779 QCQED-----CGCVHGL-----------CDNRPGSGGVCQQGT------CAPGFSGRFCN 816
+C + C C G CD P G C+ G C PG++G C
Sbjct: 542 KCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCE 601
Query: 817 ESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGDGFSCTPSNPCSHP-DRGGCSE 875
++ +C +Q C C ++ C CL G G + S P D G C +
Sbjct: 602 TNINECS----SQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLD 657
Query: 876 NAECVPGSLGTHHCTCHKGWSGDGRVC-VAIDECELDMRGGCHTDALCSYVGPGQSRCTC 934
+ + C C G++G +C + IDEC CH C G C C
Sbjct: 658 -------KIDGYECACEPGYTGS--MCNINIDEC---AGNPCHNGGTCE-DGINGFTCRC 704
Query: 935 KLGFAGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGFGG 982
G+ D S ++ C + N HG CR G + C C PG+ G
Sbjct: 705 PEGY-HDPTCLSEVNECNS-NPCVHG--ACRDSLNGYK-CDCDPGWSG 747
Score = 89.0 bits (219), Expect = 6e-17
Identities = 92/340 (27%), Positives = 120/340 (35%), Gaps = 104/340 (30%)
Query: 720 CCKGFFGPDC-TQCPGGFSNPCYGKGNCSDGIQG-------------------------- 752
C +GF GP+C T SNPC +G C D + G
Sbjct: 779 CREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPC 838
Query: 753 -NG------------ACLCFPDYKGIACHICSN-----PNKHGEQCQEDCG--------- 785
NG +C+C ++G C + N P +HG CQ G
Sbjct: 839 RNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAG 898
Query: 786 -----CVHGLCDNRPG---SGGVCQQGT------CAPGFSGRFCNESMGDCGPTGLAQHC 831
C + D RP +GG C G C PGF G FC E + +C + C
Sbjct: 899 YSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECA----SDPC 954
Query: 832 HLHARCVSQEGVARCRCLDGFEGDGFSCTPSNP-CSHPDRGGCSENAECVPGSLGTHHCT 890
A C C C GF G C + P C+ C CV G + + C
Sbjct: 955 RNGANCTDCVDSYTCTCPAGF--SGIHCENNTPDCT---ESSCFNGGTCVDG-INSFTCL 1008
Query: 891 CHKGWSGDGRVCV-AIDECELD--MRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQ--- 944
C G++G C ++EC+ + GG D G G RCTC G+ G Q
Sbjct: 1009 CPPGFTGS--YCQHDVNECDSQPCLHGGTCQD------GCGSYRCTCPQGYTGPNCQNLV 1060
Query: 945 --CSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGFGG 982
C PC+ G G C T Q C CP G+ G
Sbjct: 1061 HWCDS-SPCKNG-GKCWQTHT-------QYRCECPSGWTG 1091
Score = 88.6 bits (218), Expect = 7e-17
Identities = 84/335 (25%), Positives = 116/335 (34%), Gaps = 61/335 (18%)
Query: 55 CPSGWLRELPDQITQDCRYEVQLGGSMVSMSGCRRKCRKQVVQKAC-CP-GYWGSRCHEC 112
C +GW E + DC G+ C +V C CP G G CH
Sbjct: 323 CVNGWTGEDCSENIDDCASAACFHGAT---------CHDRVASFYCECPHGRTGLLCHLN 373
Query: 113 PGGAETPCNGHGTC-LDGMDRNGTCVCQENFRGSACQECQDPNRFGPD-CQSVCSCVHGV 170
PCN C + ++ C C + G AC + D G + C+ C++ +
Sbjct: 374 DACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTL 433
Query: 171 CNHGPRGDGSCLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAP--SCRCLPGYTQQGS 228
G C C GYTGP C+ ++ C C + C + C C+PGY +G
Sbjct: 434 ------GSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGY--EGV 485
Query: 229 ECRA-PNPCWPSPCSLLAQCSVSPKGQAQCHCPENYHG----------------DGMVCL 271
C + C SPC +C + + QC CP + G +G CL
Sbjct: 486 HCEVNTDECASSPCLHNGRC-LDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCL 544
Query: 272 PKD-----PCTDNLGGCPSNSTL-------CVYQ--KPGQA--FCTCRPGLVSINSNASA 315
CT+ G + C Y K G A C CRPG + +
Sbjct: 545 DGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNI 604
Query: 316 GCFAFCSPFSCDRSATCQVTADGKTSCVCRESEVG 350
CS C TCQ D C C + G
Sbjct: 605 N---ECSSQPCRHGGTCQ-DRDNAYLCFCLKGTTG 635
Score = 88.6 bits (218), Expect = 7e-17
Identities = 95/329 (28%), Positives = 121/329 (36%), Gaps = 64/329 (19%)
Query: 1272 CVNCTRRFRCT--QGFQ-------LQDTPRKSCVYRSGFSFSRGCSYTCAKKIQVPDCCP 1322
C +C + CT GF D SC + G S+TC C P
Sbjct: 960 CTDCVDSYTCTCPAGFSGIHCENNTPDCTESSC-FNGGTCVDGINSFTCL-------CPP 1011
Query: 1323 GFFGTLCEPCPGGLGGV-CSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCTG 1381
GF G+ C+ C G CQD GS C C +G+ G C+ N
Sbjct: 1012 GFTGSYCQHDVNECDSQPCLHGGTCQDG-CGSYRCTCPQGYTGPNCQ---------NLVH 1061
Query: 1382 VCD---CAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQC-----------PRKCDPN 1427
CD C +G C C GW GL CD + S C R C
Sbjct: 1062 WCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCD--VPSVSCEVAAQRQGVDVARLCQHG 1119
Query: 1428 ANCVQDSAGASTCACAAGYSGNGIFCSE-VDPCAHGHGGCSPHANCTKVAPGQRTCTCQD 1486
CV D+ C C AGY+G+ +C + VD C+ C A CT G +C C
Sbjct: 1120 GLCV-DAGNTHHCRCQAGYTGS--YCEDLVDECS--PSPCQNGATCTDYLGGY-SCKCVA 1173
Query: 1487 GYMGDGELCQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCEL-LDPCS 1545
GY G +EI+ CL H C C+ P CSC G G CE+ +D C+
Sbjct: 1174 GYHG-VNCSEEIDECLSH--PCQNGGTCLDL-PNTYKCSCPRGTQG---VHCEINVDDCN 1226
Query: 1546 KNNGGCSPYATCKSTGD-----GQRTCTC 1569
S C + G G +CTC
Sbjct: 1227 PPVDPVSRSPKCFNNGTCVDQVGGYSCTC 1255
Score = 86.3 bits (212), Expect = 4e-16
Identities = 99/370 (26%), Positives = 132/370 (35%), Gaps = 79/370 (21%)
Query: 1937 GRPQGL---GRGCHRNCVTTTWKPSCCPGHYGSECQA--CPGGPSSPCSDRGVCMDGMSG 1991
G+ GL G CH +++ C H G C+ P PS PC + G C
Sbjct: 183 GQKPGLCRHGGTCHNE--VGSYRCVCRATHTGPNCERPYVPCSPS-PCQNGGTCRPTGDV 239
Query: 1992 SGQCLCRSGFAGTACE--------------------------LCAPGAFGPHC----QAC 2021
+ +C C GF G CE C P G +C C
Sbjct: 240 THECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDEC 299
Query: 2022 R-----CTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEAVCR---AG 2073
+ C G C GG +C C GWTG C ++ + C A C A
Sbjct: 300 QLMPNACQNGGTCHNTHGGY-NCVCVNGWTGEDCSENID--DCASAACFHGATCHDRVAS 356
Query: 2074 NSCECSLGYEGDGRVCTVADLCQDGHGGCSEHANC--SQVGTMVTCTCLPDYEGDGWSCR 2131
CEC G G +C + D C C+E +NC + V CTC Y G S +
Sbjct: 357 FYCECPHG--RTGLLCHLNDACIS--NPCNEGSNCDTNPVNGKAICTCPSGYTGPACS-Q 411
Query: 2132 ARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGDGLQCLEESEPPVDRCLGQPPPC 2191
+ C+ G C C++T L + C+C GY G E V+ C+ PC
Sbjct: 412 DVDECSLG-ANPCEHAGKCINT-LGSFECQCLQGYTG------PRCEIDVNECVSN--PC 461
Query: 2192 HSDAMCTDLHFQEKRAGVFHLQATSGPYG----LNFSE-AEAACEAQGAVLASFPQLSAA 2246
+DA C D + G F G G +N E A + C G L +
Sbjct: 462 QNDATCLD------QIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCE 515
Query: 2247 QQLGF--HLC 2254
GF HLC
Sbjct: 516 CPTGFTGHLC 525
Score = 85.9 bits (211), Expect = 5e-16
Identities = 76/296 (25%), Positives = 101/296 (34%), Gaps = 60/296 (20%)
Query: 1320 CCPGFFGTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACE----------- 1368
C PG+ G C+ C+ GQC F S CHC FHG C
Sbjct: 129 CPPGWSGKSCQQADPCASNPCANGGQCLP-FEASYICHCPPSFHGPTCRQDVNECGQKPG 187
Query: 1369 -----------------VCELGRYGPNC-TGVCDCAHGLCQEG----LQGD--GSCVCNV 1404
VC GPNC C+ CQ G GD C C
Sbjct: 188 LCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLP 247
Query: 1405 GWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTCACAAGYSGNGIFCSE-VDPCAHGH 1463
G+ G C++ I CP N D C C ++G +C+E VD C
Sbjct: 248 GFTGQNCEENI--DDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQ--YCTEDVDECQLMP 303
Query: 1464 GGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINSC----LIHHGGCHIHAECIPTGP 1519
C C G C C +G+ G+ + + I+ C H CH
Sbjct: 304 NACQNGGTCHNTHGGY-NCVCVNGWTGE-DCSENIDDCASAACFHGATCHDRV------- 354
Query: 1520 QQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKSTG-DGQRTCTCDTAHT 1574
C C G +G C L D C N C+ + C + +G+ CTC + +T
Sbjct: 355 ASFYCECPHGRTG---LLCHLNDACISN--PCNEGSNCDTNPVNGKAICTCPSGYT 405
Score = 85.9 bits (211), Expect = 5e-16
Identities = 87/313 (27%), Positives = 112/313 (35%), Gaps = 82/313 (26%)
Query: 100 CCPGYWGSRC-HECPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGP 158
C G+ G C + P E+ C GTC+DG++ + TC+C F GS CQ D N
Sbjct: 971 CPAGFSGIHCENNTPDCTESSCFNGGTCVDGIN-SFTCLCPPGFTGSYCQH--DVN---- 1023
Query: 159 DCQSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQELPVCQELRCPQ-------NTQCS 211
+C S C+HG G C C GYTGP+C + C C +TQ
Sbjct: 1024 ECDSQ-PCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYR 1082
Query: 212 AEAPS-------------------------------------------CRCLPGYTQQGS 228
E PS CRC GYT GS
Sbjct: 1083 CECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYT--GS 1140
Query: 229 ECR-APNPCWPSPCSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPS-- 285
C + C PSPC A C+ G C C YHG C++ + C S
Sbjct: 1141 YCEDLVDECSPSPCQNGATCT-DYLGGYSCKCVAGYHGVN--------CSEEIDECLSHP 1191
Query: 286 --NSTLCVYQKPGQAFCTCRPGLVSINSNASA-GCFAFCSPFS----CDRSATCQVTADG 338
N C+ P C+C G ++ + C P S C + TC V G
Sbjct: 1192 CQNGGTCL-DLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTC-VDQVG 1249
Query: 339 KTSCVCRESEVGD 351
SC C VG+
Sbjct: 1250 GYSCTCPPGFVGE 1262
Score = 85.1 bits (209), Expect = 8e-16
Identities = 84/302 (27%), Positives = 116/302 (38%), Gaps = 66/302 (21%)
Query: 711 CNQTIMEQGCCKGFFGPDC--------TQCPGG------------FSNPCYGKGNC-SDG 749
C++ I + F G C +CP G SNPC NC ++
Sbjct: 332 CSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNP 391
Query: 750 IQGNGACLCFPDYKGIACHICSNPNKHGEQCQEDCG-CVH-GLCDNRPGSGGVCQQGTCA 807
+ G C C Y G AC ++ ++C C H G C N GS CQ C
Sbjct: 392 VNGKAICTCPSGYTGPAC------SQDVDECSLGANPCEHAGKCINTLGSFE-CQ---CL 441
Query: 808 PGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGDGFSCTPSNPCSH 867
G++G C + +C ++ C A C+ Q G +C C+ G+EG S
Sbjct: 442 QGYTGPRCEIDVNEC----VSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASS 497
Query: 868 PDRGGCSENAECVPGSLGTHHCTCHKGWSGDGRVC-VAIDECELDMRGGCHTDALCSYVG 926
P C N C+ + C C G++ G +C +DEC C A C G
Sbjct: 498 P----CLHNGRCL-DKINEFQCECPTGFT--GHLCQYDVDEC---ASTPCKNGAKC-LDG 546
Query: 927 PGQSRCTCKLGFAG-----DGYQCSPIDPCRAGNGGC-HGLATCRAVGGGQRVCTCPPGF 980
P C C G+ G D +C P DPC G+ C G+AT C C PG+
Sbjct: 547 PNTYTCVCTEGYTGTHCEVDIDECDP-DPCHYGS--CKDGVATF--------TCLCRPGY 595
Query: 981 GG 982
G
Sbjct: 596 TG 597
Score = 84.7 bits (208), Expect = 1e-15
Identities = 107/415 (25%), Positives = 144/415 (34%), Gaps = 114/415 (27%)
Query: 665 SCVDCQALNTSTCPP--NSVKLDIFPKECVYIHDPTGLNVLKKG-CASYCNQTIMEQGCC 721
+C DC T TCP + + + +C T + G C N C
Sbjct: 959 NCTDCVDSYTCTCPAGFSGIHCENNTPDC------TESSCFNGGTCVDGINSFTCL--CP 1010
Query: 722 KGFFGPDC----TQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIAC----HIC-SN 772
GF G C +C S PC G C DG G+ C C Y G C H C S+
Sbjct: 1011 PGFTGSYCQHDVNECD---SQPCLHGGTCQDGC-GSYRCTCPQGYTGPNCQNLVHWCDSS 1066
Query: 773 PNKHGEQC-----QEDCGCVHG----LCD----------NRPG--------SGGVCQQG- 804
P K+G +C Q C C G CD R G GG+C
Sbjct: 1067 PCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAG 1126
Query: 805 -----TCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGDGFSC 859
C G++G +C + + +C P+ C A C G C+C+ G+ G S
Sbjct: 1127 NTHHCRCQAGYTGSYCEDLVDECSPSP----CQNGATCTDYLGGYSCKCVAGYHGVNCSE 1182
Query: 860 TPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGRVCVAIDECE-----LDMRG 914
SHP C C+ T+ C+C +G G + +D+C +
Sbjct: 1183 EIDECLSHP----CQNGGTCL-DLPNTYKCSCPRGTQG-VHCEINVDDCNPPVDPVSRSP 1236
Query: 915 GCHTDALCSYVGPGQSRCTCKLGFA-----GDGYQC--SPID----------------PC 951
C + C G S CTC GF GD +C +P D C
Sbjct: 1237 KCFNNGTCVDQVGGYS-CTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCEC 1295
Query: 952 RAGNGG--------------CHGLATCRAVGGGQR--VCTCPPGFGGDGFSCYGD 990
RAG+ G C TC R +C CP GF +G +C D
Sbjct: 1296 RAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGF--EGATCEND 1348
Score = 84.0 bits (206), Expect = 2e-15
Identities = 77/261 (29%), Positives = 107/261 (40%), Gaps = 43/261 (16%)
Query: 1951 VTTTWKPSCCPGHYGSECQACPGG-PSSPCSDRGVCMDGMSGSGQCLCRSGFAGTACELC 2009
+T+ + +C G G CQ S+PC ++G C+D ++G +C C + G CE+
Sbjct: 771 MTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGY-KCNCLLPYTGATCEVV 829
Query: 2010 -APGAFGPHCQACRCTVHGRCDEGLG-GSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPE 2067
AP A P C G C + S SC C GW G CEV ++ PC
Sbjct: 830 LAPCAPSP------CRNGGECRQSEDYESFSCVCPTGWQGQTCEV--DINECVLSPCRHG 881
Query: 2068 AVCR---AGNSCECSLGYEGDGRVC-TVADLCQDGHGGCSEHANCSQVGTMVTCTCLPDY 2123
A C+ G C C GY GR C T D C+ C +C+ C CLP +
Sbjct: 882 ASCQNTHGGYRCHCQAGY--SGRNCETDIDDCRP--NPCHNGGSCTDGINTAFCDCLPGF 937
Query: 2124 EG-----DGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGDGLQCLEESE 2178
G D C A +PC +G ANC +++ C C AG+ G+ C E +
Sbjct: 938 RGTFCEEDINEC-ASDPCRNG--------ANCTDC-VDSYTCTCPAGF--SGIHC-ENNT 984
Query: 2179 PPVDRCLGQPPPCHSDAMCTD 2199
P C + C D
Sbjct: 985 PDCTE-----SSCFNGGTCVD 1000
Score = 84.0 bits (206), Expect = 2e-15
Identities = 93/357 (26%), Positives = 114/357 (31%), Gaps = 65/357 (18%)
Query: 44 CTSCAAIKKQTCPSGWLRELPDQITQDCRYEVQLGGSMVSMSGCRRKCRKQVVQKACCPG 103
CT C TCP+G+ + T DC G C C PG
Sbjct: 960 CTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTC-------LCPPG 1012
Query: 104 YWGSRC-HECPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQEC-----QDPNRFG 157
+ GS C H+ PC GTC DG + C C + + G CQ P + G
Sbjct: 1013 FTGSYCQHDVNECDSQPCLHGGTCQDGCG-SYRCTCPQGYTGPNCQNLVHWCDSSPCKNG 1071
Query: 158 PDC-----QSVCSCVHG--------------------------VCNHG-----PRGDGSC 181
C Q C C G +C HG C
Sbjct: 1072 GKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHC 1131
Query: 182 LCFAGYTGPHCDQELPVCQELRCPQNTQCS--AEAPSCRCLPGYTQQGSECRAP-NPCWP 238
C AGYTG +C+ + C C C+ SC+C+ GY G C + C
Sbjct: 1132 RCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGY--HGVNCSEEIDECLS 1189
Query: 239 SPCSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKD--PCTDNLGGCPS--NSTLCVYQK 294
PC C P +C CP G D P D + P N+ CV Q
Sbjct: 1190 HPCQNGGTCLDLP-NTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQV 1248
Query: 295 PGQAFCTCRPGLVSINSNASAGCFAFCSPFSCDRSATCQ-VTADGKTSCVCRESEVG 350
G + CTC PG V G C CD T V C CR G
Sbjct: 1249 GGYS-CTCPPGFV---GERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTG 1301
Score = 82.8 bits (203), Expect = 4e-15
Identities = 77/288 (26%), Positives = 101/288 (35%), Gaps = 63/288 (21%)
Query: 99 ACCPGYWGSRCH----ECPGGAETPCNGHGTCLDGMDRNG-TCVCQENFRGSACQE---- 149
AC PGY GS C+ EC G PC+ GTC DG+ NG TC C E + C
Sbjct: 665 ACEPGYTGSMCNINIDECAGN---PCHNGGTCEDGI--NGFTCRCPEGYHDPTCLSEVNE 719
Query: 150 ----------CQDP-NRFGPDCQ-----SVCSCVHGVCNHGPRGDGS----------CLC 183
C+D N + DC + C + C P +G C C
Sbjct: 720 CNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTC 779
Query: 184 FAGYTGPHCDQELPVCQELRCPQNTQCSAEAP--SCRCLPGYTQQGSECRAP-NPCWPSP 240
G++GP+C + C C C + C CL YT G+ C PC PSP
Sbjct: 780 REGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYT--GATCEVVLAPCAPSP 837
Query: 241 CSLLAQCSVSPKGQA-QCHCPENYHGDGMVCLPKDPCTDNLGGC---PSNSTLCVYQKPG 296
C +C S ++ C CP + G C ++ C P G
Sbjct: 838 CRNGGECRQSEDYESFSCVCPTGWQG--------QTCEVDINECVLSPCRHGASCQNTHG 889
Query: 297 QAFCTCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVTADGKTSCVC 344
C C+ G N C P C +C DG + C
Sbjct: 890 GYRCHCQAGYSGRNCETD---IDDCRPNPCHNGGSC---TDGINTAFC 931
Score = 82.0 bits (201), Expect = 7e-15
Identities = 67/249 (26%), Positives = 91/249 (36%), Gaps = 39/249 (15%)
Query: 1959 CCPGHYGSECQACPGG-PSSPCSDRGVCMDGMSGSGQCLCRSGFAGTACELCAPGAFGPH 2017
C PG+ G C+ SSPC G C+D ++ QC C +GF G C+
Sbjct: 478 CMPGYEGVHCEVNTDECASSPCLHNGRCLDKIN-EFQCECPTGFTGHLCQYDV-----DE 531
Query: 2018 CQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEAVCRAG---N 2074
C + C +C +G + +C C EG+TG CEV ++ C P C+ G
Sbjct: 532 CASTPCKNGAKCLDG-PNTYTCVCTEGYTGTHCEVDID---ECDPDPCHYGSCKDGVATF 587
Query: 2075 SCECSLGYEGDGRVCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWSCR--- 2131
+C C GY G + + C C C CL G
Sbjct: 588 TCLCRPGYTGHHCETNINECSSQ---PCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDD 644
Query: 2132 -ARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGDGLQCLEESEPPVDRCLGQPPP 2190
A +PC G CL ++ C C GY G C +D C G P
Sbjct: 645 CASSPCDSG---------TCLDK-IDGYECACEPGYTGS--MC----NINIDECAGN--P 686
Query: 2191 CHSDAMCTD 2199
CH+ C D
Sbjct: 687 CHNGGTCED 695
Score = 81.3 bits (199), Expect = 1e-14
Identities = 77/299 (25%), Positives = 102/299 (34%), Gaps = 49/299 (16%)
Query: 720 CCKGFFGPDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPN----- 774
C G+ G C Q SNPC G C + + C C P + G C N
Sbjct: 129 CPPGWSGKSCQQADPCASNPCANGGQCLP-FEASYICHCPPSFHGPTCRQDVNECGQKPG 187
Query: 775 --KHGEQCQEDCGCVHGLCDNR-----------PGSGGVCQQG-------------TCAP 808
+HG C + G +C P S CQ G C P
Sbjct: 188 LCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLP 247
Query: 809 GFSGRFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGDGFSCTPSNPCSHP 868
GF+G+ C E++ DC +C CV CRC E G CT
Sbjct: 248 GFTGQNCEENIDDCP----GNNCKNGGACVDGVNTYNCRCPP--EWTGQYCTEDVDECQL 301
Query: 869 DRGGCSENAECVPGSLGTHHCTCHKGWSGDGRVCVAIDECELDMRGGCHTDALCSYVGPG 928
C C + G ++C C GW+G+ ID+C C A C +
Sbjct: 302 MPNACQNGGTC-HNTHGGYNCVCVNGWTGED-CSENIDDC---ASAACFHGATC-HDRVA 355
Query: 929 QSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRA-VGGGQRVCTCPPGFGGDGFS 986
C C G G C D C + C+ + C G+ +CTCP G+ G S
Sbjct: 356 SFYCECPHG--RTGLLCHLNDACI--SNPCNEGSNCDTNPVNGKAICTCPSGYTGPACS 410
Score = 81.3 bits (199), Expect = 1e-14
Identities = 88/317 (27%), Positives = 122/317 (38%), Gaps = 57/317 (17%)
Query: 1272 CVNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKKIQVPDCCPGFFGTLCEP 1331
CVN C++ + D +C + R S+ C +C G G LC
Sbjct: 323 CVNGWTGEDCSEN--IDDCASAAC-FHGATCHDRVASFYC-------ECPHGRTGLLCHL 372
Query: 1332 CPGGLGGVCSGHGQCQDRFL-GSGECHCHEGFHGTAC----EVCELGRYGPNCTGVCDCA 1386
+ C+ C + G C C G+ G AC + C LG C
Sbjct: 373 NDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGAN--------PCE 424
Query: 1387 H-GLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQC-PRKCDPNANCVQDSAGASTCACAA 1444
H G C L G C C G+ G RC+ + +C C +A C+ D G C C
Sbjct: 425 HAGKCINTL-GSFECQCLQGYTGPRCEIDVN--ECVSNPCQNDATCL-DQIGEFQCICMP 480
Query: 1445 GYSG-----NGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQ-EI 1498
GY G N C+ PC H +G C N + C C G+ G LCQ ++
Sbjct: 481 GYEGVHCEVNTDECAS-SPCLH-NGRCLDKIN-------EFQCECPTGFTG--HLCQYDV 529
Query: 1499 NSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCEL-LDPCSKNNGGCSPYATC 1557
+ C C A+C+ GP +C C EGY+G CE+ +D C + Y +C
Sbjct: 530 DECA--STPCKNGAKCLD-GPNTYTCVCTEGYTG---THCEVDIDECDPDP---CHYGSC 580
Query: 1558 KSTGDGQRTCTCDTAHT 1574
K G TC C +T
Sbjct: 581 KD-GVATFTCLCRPGYT 596
Score = 81.3 bits (199), Expect = 1e-14
Identities = 89/306 (29%), Positives = 117/306 (38%), Gaps = 81/306 (26%)
Query: 1319 DCCPGFFGTLCE---------PCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACE- 1368
DC PG+ GT C+ PC G G C+D G C C EGF G C+
Sbjct: 740 DCDPGWSGTNCDINNNECESNPCVNG--------GTCKDMTSGY-VCTCREGFSGPNCQT 790
Query: 1369 ----------------VCELGRYGPNC----TGV-CD-----CAHGLCQEGLQ------- 1395
+ ++ Y NC TG C+ CA C+ G +
Sbjct: 791 NINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDY 850
Query: 1396 GDGSCVCNVGWQGLRCDQKITSPQCP-RKCDPNANCVQDSAGASTCACAAGYSGNGIFCS 1454
SCVC GWQG C+ I +C C A+C Q++ G C C AGYSG +
Sbjct: 851 ESFSCVCPTGWQGQTCEVDIN--ECVLSPCRHGASC-QNTHGGYRCHCQAGYSGRNCE-T 906
Query: 1455 EVDPC----AHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQE-INSCLIHHGGCH 1509
++D C H G C+ N C C G+ G C+E IN C C
Sbjct: 907 DIDDCRPNPCHNGGSCTDGINTA-------FCDCLPGFR--GTFCEEDINECA--SDPCR 955
Query: 1510 IHAECIPTGPQQVSCSCREGYSGDGIRTCELLDP-CSKNNGGCSPYATCKSTGDGQRTCT 1568
A C +C+C G+SG CE P C++++ C TC G TC
Sbjct: 956 NGANCTDC-VDSYTCTCPAGFSG---IHCENNTPDCTESS--CFNGGTCVD-GINSFTCL 1008
Query: 1569 CDTAHT 1574
C T
Sbjct: 1009 CPPGFT 1014
Score = 80.5 bits (197), Expect = 2e-14
Identities = 81/307 (26%), Positives = 105/307 (34%), Gaps = 61/307 (19%)
Query: 720 CCKGFFGPDCTQCPGGFSNPCYGKG---------------NCSDGIQG-------NGACL 757
C F GP C S PC G +C+ G G + ACL
Sbjct: 48 CGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACL 107
Query: 758 CFPDYKGIACHICS--------NPNKHGEQCQEDCGCVHGLCDNRPGSGGVCQQGT---- 805
P G C + + P G+ CQ+ C C N GG C
Sbjct: 108 TNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCAN----GGQCLPFEASYI 163
Query: 806 --CAPGFSGRFCNESMGDCG-PTGLAQHCHLHARCVSQEGVARCRCLDGFEGDGFSCTPS 862
C P F G C + + +CG GL +H C ++ G RC C G P
Sbjct: 164 CHCPPSFHGPTCRQDVNECGQKPGLCRH---GGTCHNEVGSYRCVCRATHTGPNCE-RPY 219
Query: 863 NPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGRVCVA-IDECELD--MRGGCHTD 919
PCS C C P TH C C G++G C ID+C + GG D
Sbjct: 220 VPCS---PSPCQNGGTCRPTGDVTHECACLPGFTGQN--CEENIDDCPGNNCKNGGACVD 274
Query: 920 ALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPG 979
+ +Y C C + G Y +D C+ C TC GG C C G
Sbjct: 275 GVNTY------NCRCPPEWTGQ-YCTEDVDECQLMPNACQNGGTCHNTHGGYN-CVCVNG 326
Query: 980 FGGDGFS 986
+ G+ S
Sbjct: 327 WTGEDCS 333
Score = 79.3 bits (194), Expect = 4e-14
Identities = 95/366 (25%), Positives = 131/366 (35%), Gaps = 89/366 (24%)
Query: 1254 TVGSSRCLHSHAEALREKCVNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRGCSYTCAK 1313
++G++ C H+ KC+N F C Q Q PR C S C
Sbjct: 417 SLGANPCEHAG------KCINTLGSFEC-QCLQGYTGPR--CEIDVNECVSNPCQNDATC 467
Query: 1314 KIQVPD----CCPGFFGTLCEPCPGGLGGV-CSGHGQCQDRFLGSGECHCHEGFHGTACE 1368
Q+ + C PG+ G CE C +G+C D+ + +C C GF G C+
Sbjct: 468 LDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDK-INEFQCECPTGFTGHLCQ 526
Query: 1369 VCELGRYGPNCTGVCDCAHGLCQEGLQG-DG----SCVCNVGWQGLRCDQKITSPQCPRK 1423
V +CA C+ G + DG +CVC G+ G C+ I +
Sbjct: 527 Y-----------DVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDID------E 569
Query: 1424 CDPNA---NCVQDSAGASTCACAAGYSG-----NGIFCSEVDPCAHGHGGCSPHAN---- 1471
CDP+ +D TC C GY+G N CS PC HG G C N
Sbjct: 570 CDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNINECSS-QPCRHG-GTCQDRDNAYLC 627
Query: 1472 -CTKVAPGQR-------------------------TCTCQDGYMGDGELCQ-EINSCLIH 1504
C K G C C+ GY G +C I+ C
Sbjct: 628 FCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGY--TGSMCNINIDECA-- 683
Query: 1505 HGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKSTGDGQ 1564
CH C G +C C EGY TC L ++ N + C+ + +G
Sbjct: 684 GNPCHNGGTC-EDGINGFTCRCPEGYHDP---TC--LSEVNECNSNPCVHGACRDSLNGY 737
Query: 1565 RTCTCD 1570
+ C CD
Sbjct: 738 K-CDCD 742
Score = 77.8 bits (190), Expect = 1e-13
Identities = 79/313 (25%), Positives = 105/313 (33%), Gaps = 69/313 (22%)
Query: 90 KCRKQVVQKACCPG--YWGSRCHECPGGAETPCNGHGTCLDGMDRNG----TCVCQENFR 143
KC +AC G + G RC + TPC GTC +DR G C C F
Sbjct: 36 KCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTC-HVVDRRGVADYACSCALGFS 94
Query: 144 GSAC----------QECQD-----------------PNRFGPDCQSVCSCVHGVCNHGPR 176
G C C++ P G CQ C C +G +
Sbjct: 95 GPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQ 154
Query: 177 -----GDGSCLCFAGYTGPHCDQELPVCQEL--RCPQNTQCSAEAPSCRCLPGYTQQGSE 229
C C + GP C Q++ C + C C E S RC+ T G
Sbjct: 155 CLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPN 214
Query: 230 CRAPN-PCWPSPCSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPSNST 288
C P PC PSPC C + +C C + G C +N+ CP N+
Sbjct: 215 CERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQN--------CEENIDDCPGNNC 266
Query: 289 LCVYQKPGQAFCTCRPGLVSINSNASAGCFA-FCS---------PFSCDRSATCQVTADG 338
K G A C G+ + N +C+ P +C TC T G
Sbjct: 267 -----KNGGA---CVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNT-HG 317
Query: 339 KTSCVCRESEVGD 351
+CVC G+
Sbjct: 318 GYNCVCVNGWTGE 330
Score = 75.1 bits (183), Expect = 8e-13
Identities = 80/317 (25%), Positives = 104/317 (32%), Gaps = 100/317 (31%)
Query: 1959 CCPGHYGSECQA-CPGGPSSPCSDRGVCMDGMSGSGQCLCRSGFAGTACE---------- 2007
C G G CQ S+PC + C+DG + + C+C G+ GT CE
Sbjct: 516 CPTGFTGHLCQYDVDECASTPCKNGAKCLDGPN-TYTCVCTEGYTGTHCEVDIDECDPDP 574
Query: 2008 ---------------LCAPGAFGPHC---------QACRCTVHGRCDEGLGGSGSCFCDE 2043
LC PG G HC Q CR HG + + CFC +
Sbjct: 575 CHYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCR---HGGTCQDRDNAYLCFCLK 631
Query: 2044 GWTGPRCEVQLELQPVCTPPCAPEAVCR---AGNSCECSLGYEGD----------GRVCT 2090
G TGP CE+ L+ + PC C G C C GY G G C
Sbjct: 632 GTTGPNCEINLD--DCASSPC-DSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCH 688
Query: 2091 VADLCQDGHGG----CSE--------------------HANCSQVGTMVTCTCLPDYEGD 2126
C+DG G C E H C C C P + G
Sbjct: 689 NGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGT 748
Query: 2127 GWSCR----ARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGDGLQCLEESEPPVD 2182
NPC +G G C + +++G C C G+ G Q ++
Sbjct: 749 NCDINNNECESNPCVNG--GTCKD----MTSGY---VCTCREGFSGPNCQ------TNIN 793
Query: 2183 RCLGQPPPCHSDAMCTD 2199
C PC + C D
Sbjct: 794 ECASN--PCLNQGTCID 808
Score = 75.1 bits (183), Expect = 8e-13
Identities = 81/316 (25%), Positives = 102/316 (32%), Gaps = 79/316 (25%)
Query: 720 CCKGFFGPDCTQCPGGFS-NPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGE 778
C G+ G C S +PC C+D + G +C C Y G+ C E
Sbjct: 1133 CQAGYTGSYCEDLVDECSPSPCQNGATCTDYL-GGYSCKCVAGYHGVNC---------SE 1182
Query: 779 QCQEDCGCVHGLCDNRPGSGGVC------QQGTCAPGFSGRFCNESMGDCGP----TGLA 828
+ E C+ C N GG C + +C G G C ++ DC P +
Sbjct: 1183 EIDE---CLSHPCQN----GGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRS 1235
Query: 829 QHCHLHARCVSQEGVARCRCLDGF-----EGDGFSCTPSNPCSHPDRGGCSENAECVPGS 883
C + CV Q G C C GF EGD C SNPC C +
Sbjct: 1236 PKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECL-SNPCDARGTQNCVQR------- 1287
Query: 884 LGTHHCTCHKGWSG----------------DGRVCVA--------IDECELDMRGG-CHT 918
+ HC C G +G +G C I +C G C
Sbjct: 1288 VNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCEN 1347
Query: 919 DA-LCSYV----------GPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRAV 967
DA C + GP C C F G Q PC GN C+ TC
Sbjct: 1348 DARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGN-PCYNQGTCEPT 1406
Query: 968 GGGQRV-CTCPPGFGG 982
C CP F G
Sbjct: 1407 SESPFYRCLCPAKFNG 1422
Score = 74.3 bits (181), Expect = 1e-12
Identities = 73/268 (27%), Positives = 97/268 (36%), Gaps = 70/268 (26%)
Query: 1281 CTQGFQLQDTPRK-SCVYRSGFSFSRGCSYTCAKKIQVPDCCPGFFGTLCEPCPGGLGGV 1339
C G Q+T C ++G+S R C + + DC P PC G
Sbjct: 878 CRHGASCQNTHGGYRCHCQAGYS-GRNC------ETDIDDCRPN-------PCHNG---- 919
Query: 1340 CSGHGQCQDRFLGSGECHCHEGFHGTACE------VCELGRYGPNCTGVCDCAHGLCQEG 1393
G C D + + C C GF GT CE + R G NCT DC
Sbjct: 920 ----GSCTDG-INTAFCDCLPGFRGTFCEEDINECASDPCRNGANCT---DCVDSY---- 967
Query: 1394 LQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTCACAAGYSGNGIFC 1453
+C C G+ G+ C+ +P C N D + TC C G++G+ +C
Sbjct: 968 -----TCTCPAGFSGIHCENN--TPDCTESSCFNGGTCVDGINSFTCLCPPGFTGS--YC 1018
Query: 1454 S------EVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINSCLIH--- 1504
+ PC HG G C G CTC GY G CQ L+H
Sbjct: 1019 QHDVNECDSQPCLHG-GTCQDGC-------GSYRCTCPQGYTGPN--CQN----LVHWCD 1064
Query: 1505 HGGCHIHAECIPTGPQQVSCSCREGYSG 1532
C +C T Q C C G++G
Sbjct: 1065 SSPCKNGGKCWQT-HTQYRCECPSGWTG 1091
Score = 72.0 bits (175), Expect = 7e-12
Identities = 71/263 (26%), Positives = 88/263 (33%), Gaps = 38/263 (14%)
Query: 1950 CVTTTWKPSC-CPGHY-GSECQACPGGPSSPCSDRGVCMDGMSGSGQCLCRSGFAGTACE 2007
C +C C G + G CQ S+PC + G C + R G A AC
Sbjct: 37 CEAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTC--------HVVDRRGVADYACS 88
Query: 2008 LCAPGAFGPHC-----QAC---RCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPV 2059
CA G GP C AC C G CD C C GW+G C+ + P
Sbjct: 89 -CALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQ---QADPC 144
Query: 2060 CTPPCAPEAVC---RAGNSCECSLGYEGDGRVCTVADLCQDGHGGCSEHANCSQVGTMVT 2116
+ PCA C A C C + G V + C G C C
Sbjct: 145 ASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNE-CGQKPGLCRHGGTCHNEVGSYR 203
Query: 2117 CTCLPDYEGDGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGDGLQCLEE 2176
C C + G R PC+ C C TG T C C G+ G +
Sbjct: 204 CVCRATHTGPNCE-RPYVPCSP---SPCQNGGTCRPTGDVTHECACLPGFTG------QN 253
Query: 2177 SEPPVDRCLGQPPPCHSDAMCTD 2199
E +D C G C + C D
Sbjct: 254 CEENIDDCPGN--NCKNGGACVD 274
Score = 71.6 bits (174), Expect = 9e-12
Identities = 78/293 (26%), Positives = 107/293 (36%), Gaps = 61/293 (20%)
Query: 1959 CCPGHYGSEC-QACPGGPSSPCSDRGVCMDGMSGSGQCLCRSGFAGTACEL----CAPGA 2013
C G++G C + S PC + G C+D + + +C C G G CE+ C P
Sbjct: 1171 CVAGYHGVNCSEEIDECLSHPCQNGGTCLD-LPNTYKCSCPRGTQGVHCEINVDDCNPPV 1229
Query: 2014 FGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLE--LQPVCTPPCAPEAVCR 2071
P ++ +C +G C + +GG SC C G+ G RCE + L C V R
Sbjct: 1230 -DPVSRSPKCFNNGTCVDQVGGY-SCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQR 1287
Query: 2072 AGN-SCECSLGYEG----------------DGRVCTVAD--------LCQDGHGG--CSE 2104
+ CEC G+ G +G C VA C G G C
Sbjct: 1288 VNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCEN 1347
Query: 2105 HA------NCSQVGTMV------TCTCLPDYEGDGWSCRARNPCTDGHRGGCSEHANCLS 2152
A C GT + TC CL + G A +PC G+ C C
Sbjct: 1348 DARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGN--PCYNQGTCEP 1405
Query: 2153 TGLNT-RRCECHAGYVGDGLQCLEES---------EPPVDRCLGQPPPCHSDA 2195
T + RC C A + G L+ S PP+ + P C DA
Sbjct: 1406 TSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDIPPPLIEEACELPECQEDA 1458
Score = 70.1 bits (170), Expect = 3e-11
Identities = 69/256 (26%), Positives = 91/256 (35%), Gaps = 42/256 (16%)
Query: 1331 PCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCTGVCDCAHGLC 1390
P G CS G+ L G+C E +GT VC GP C C C
Sbjct: 15 PALAARGPRCSQPGET---CLNGGKC---EAANGTEACVCGGAFVGPRCQDPNPCLSTPC 68
Query: 1391 QEGLQ---------GDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTCA 1441
+ D +C C +G+ G C + + C C + C
Sbjct: 69 KNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCR 128
Query: 1442 CAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELC-QEINS 1500
C G+SG C + DPCA +P AN + P + + C G C Q++N
Sbjct: 129 CPPGWSGKS--CQQADPCA-----SNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNE 181
Query: 1501 C-----LIHHGG-CHIHAECIPTGPQQVSCSCREGYSGDGIRTCEL-LDPCSKNNGGCSP 1553
C L HGG CH C CR ++G CE PCS + C
Sbjct: 182 CGQKPGLCRHGGTCHNEV-------GSYRCVCRATHTGP---NCERPYVPCSPS--PCQN 229
Query: 1554 YATCKSTGDGQRTCTC 1569
TC+ TGD C C
Sbjct: 230 GGTCRPTGDVTHECAC 245
Score = 70.1 bits (170), Expect = 3e-11
Identities = 69/264 (26%), Positives = 97/264 (36%), Gaps = 51/264 (19%)
Query: 1339 VCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCTGVCDCAHGLCQEGLQ--- 1395
+C G C D + C C G+ G+ CE V +C+ CQ G
Sbjct: 1115 LCQHGGLCVDAG-NTHHCRCQAGYTGSYCEDL-----------VDECSPSPCQNGATCTD 1162
Query: 1396 --GDGSCVCNVGWQGLRCDQKITSPQC-PRKCDPNANCVQDSAGASTCACAAGYSGNGIF 1452
G SC C G+ G+ C ++I +C C C+ D C+C G G+
Sbjct: 1163 YLGGYSCKCVAGYHGVNCSEEI--DECLSHPCQNGGTCL-DLPNTYKCSCPRG--TQGVH 1217
Query: 1453 CS-EVDPC------AHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQ-EINSCLIH 1504
C VD C C + C G +CTC G++ GE C+ ++N CL +
Sbjct: 1218 CEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGY-SCTCPPGFV--GERCEGDVNECLSN 1274
Query: 1505 HGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKSTGDGQ 1564
C+ C CR G++G R CE + GC CK+ G
Sbjct: 1275 PCDARGTQNCVQR-VNDFHCECRAGHTG---RRCESV------INGCKG-KPCKNGG--- 1320
Query: 1565 RTCTCDTAHTVGDGLTCRARVGLE 1588
TC A G C+ G E
Sbjct: 1321 ---TCAVASNTARGFICKCPAGFE 1341
Score = 69.7 bits (169), Expect = 3e-11
Identities = 60/231 (25%), Positives = 81/231 (35%), Gaps = 32/231 (13%)
Query: 1975 PSSPCSDRGVCMDGMSGSGQCLCRSGFAGTACELCAPGAFGPHCQACRCTVHGRC---DE 2031
P C + G C + +G+ C+C F G C+ P C + C G C D
Sbjct: 27 PGETCLNGGKC-EAANGTEACVCGGAFVGPRCQDPNP------CLSTPCKNAGTCHVVDR 79
Query: 2032 GLGGSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEAVC----RAGNSCECSLGYEGDGR 2087
+C C G++GP C L+ T PC C C C G+ G+
Sbjct: 80 RGVADYACSCALGFSGPLCLTPLD-NACLTNPCRNGGTCDLLTLTEYKCRCPPGW--SGK 136
Query: 2088 VCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWSCRAR-NPCTDGHRGGCSE 2146
C AD C C+ C C C P + G +CR N C G + G
Sbjct: 137 SCQQADPC--ASNPCANGGQCLPFEASYICHCPPSFHGP--TCRQDVNEC--GQKPGLCR 190
Query: 2147 HANCLSTGLNTRRCECHAGYVGDGLQCLEESEPPVDRCLGQPPPCHSDAMC 2197
H + + RC C A + G E P C P PC + C
Sbjct: 191 HGGTCHNEVGSYRCVCRATHTG------PNCERPYVPC--SPSPCQNGGTC 233
Score = 68.6 bits (166), Expect = 8e-11
Identities = 75/284 (26%), Positives = 97/284 (34%), Gaps = 68/284 (23%)
Query: 1953 TTWKPSCCPGHYGSECQACPGGPSSPCSDRGVCMDGMSGSGQCLCRSGFAGTACELCAPG 2012
T +K C PG G CQ S+PC++ G C+ S C C F G C
Sbjct: 123 TEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLP-FEASYICHCPPSFHGPTCRQDV-N 180
Query: 2013 AFGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEAVCRA 2072
G CR HG GS C C TGP CE +P PC+P
Sbjct: 181 ECGQKPGLCR---HGGTCHNEVGSYRCVCRATHTGPNCE-----RPYV--PCSPSP---- 226
Query: 2073 GNSCECSLGYEGDGRVCTVADLCQDGHGGCSEHANCSQVGTMV-TCTCLPDYEGDGWSCR 2131
CQ+G C G + C CLP + G +C
Sbjct: 227 ----------------------CQNG-------GTCRPTGDVTHECACLPGFTGQ--NCE 255
Query: 2132 ARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGDGLQCLEESEPPVDRCLGQPPPC 2191
G+ C C+ G+NT C C + G C E+ VD C P C
Sbjct: 256 ENIDDCPGN--NCKNGGACVD-GVNTYNCRCPPEWTGQ--YCTED----VDECQLMPNAC 306
Query: 2192 HSDAMCTDLHFQEKRAGVFHLQATSGPYGLNFSE-----AEAAC 2230
+ C + H G ++ +G G + SE A AAC
Sbjct: 307 QNGGTCHNTH------GGYNCVCVNGWTGEDCSENIDDCASAAC 344
Score = 68.2 bits (165), Expect = 1e-10
Identities = 53/178 (29%), Positives = 81/178 (45%), Gaps = 22/178 (12%)
Query: 100 CCPGYWGSRC----HECPGGAETPCNGHGT--CLDGMDRNGTCVCQENFRGSACQECQDP 153
C PG+ G RC +EC PC+ GT C+ ++ + C C+ G C+ +
Sbjct: 1255 CPPGFVGERCEGDVNEC---LSNPCDARGTQNCVQRVN-DFHCECRAGHTGRRCESVING 1310
Query: 154 NRFGPDCQSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQELPVCQELRCPQNTQC--S 211
+ G C++ +C V ++ RG C C AG+ G C+ + C LRC C
Sbjct: 1311 CK-GKPCKNGGTCA--VASNTARGF-ICKCPAGFEGATCENDARTCGSLRCLNGGTCISG 1366
Query: 212 AEAPSCRCLPGYTQQGSECRAP--NPC-WPSPCSLLAQCS-VSPKGQAQCHCPENYHG 265
+P+C CL +T G EC+ P +PC +PC C S +C CP ++G
Sbjct: 1367 PRSPTCLCLGPFT--GPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNG 1422
Score = 66.6 bits (161), Expect = 3e-10
Identities = 54/240 (22%), Positives = 77/240 (32%), Gaps = 67/240 (27%)
Query: 157 GPDC-QSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQELPVCQELRCPQNTQC----- 210
GP C Q +C++G G +C+C + GP C P C C C
Sbjct: 21 GPRCSQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQDPNP-CLSTPCKNAGTCHVVDR 79
Query: 211 -----------------------------------------SAEAPSCRCLPGYTQQGSE 229
+ CRC PG++ G
Sbjct: 80 RGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWS--GKS 137
Query: 230 CRAPNPCWPSPCSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPSNSTL 289
C+ +PC +PC+ QC + + CHCP ++HG C ++ C L
Sbjct: 138 CQQADPCASNPCANGGQC-LPFEASYICHCPPSFHG--------PTCRQDVNECGQKPGL 188
Query: 290 C-----VYQKPGQAFCTCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVTADGKTSCVC 344
C + + G C CR N + CSP C TC+ T D C C
Sbjct: 189 CRHGGTCHNEVGSYRCVCRATHTGPNCERP---YVPCSPSPCQNGGTCRPTGDVTHECAC 245
Score = 65.1 bits (157), Expect = 9e-10
Identities = 69/267 (25%), Positives = 92/267 (34%), Gaps = 43/267 (16%)
Query: 100 CCPGYWGSRC-HECPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQ----ECQ--- 151
C GY G C E PC GTCLD + C C +G C+ +C
Sbjct: 1171 CVAGYHGVNCSEEIDECLSHPCQNGGTCLD-LPNTYKCSCPRGTQGVHCEINVDDCNPPV 1229
Query: 152 DPNRFGPDCQSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQELPVCQELRC----PQN 207
DP P C + +CV V G SC C G+ G C+ ++ C C QN
Sbjct: 1230 DPVSRSPKCFNNGTCVDQV------GGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQN 1283
Query: 208 TQCSAEAPSCRCLPGYTQQGSECRAP-NPCWPSPCSLLAQCSVSPKGQAQ--CHCPENYH 264
C C G+T G C + N C PC C+V+ C CP +
Sbjct: 1284 CVQRVNDFHCECRAGHT--GRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFE 1341
Query: 265 GDGMVCLPKDPCTDNLGGCPS----NSTLCVYQKPGQAFCTCRPGLVSINSN--ASAGCF 318
G C ++ C S N C+ P C C AS+ C
Sbjct: 1342 G--------ATCENDARTCGSLRCLNGGTCI-SGPRSPTCLCLGPFTGPECQFPASSPCL 1392
Query: 319 AFCSPFSCDRSATCQVTADGK-TSCVC 344
C TC+ T++ C+C
Sbjct: 1393 ---GGNPCYNQGTCEPTSESPFYRCLC 1416
Score = 60.8 bits (146), Expect = 2e-08
Identities = 87/352 (24%), Positives = 121/352 (34%), Gaps = 60/352 (17%)
Query: 1272 CVNCTRRFRC-----TQGFQLQDT-----PRKSCVYRSGFSFSRGCSYTCAKKIQVPDCC 1321
C++ ++C TQG + P V RS F+ G TC ++ C
Sbjct: 1198 CLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNG---TCVDQVGGYSCT 1254
Query: 1322 --PGFFGTLCE-PCPGGLGGVCSGHG--QCQDRFLGSGECHCHEGFHGTACEVCELGRYG 1376
PGF G CE L C G C R + C C G G CE G G
Sbjct: 1255 CPPGFVGERCEGDVNECLSNPCDARGTQNCVQR-VNDFHCECRAGHTGRRCESVINGCKG 1313
Query: 1377 PNCT--GVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDS 1434
C G C A + + C C G++G C+ + R C C+
Sbjct: 1314 KPCKNGGTCAVASNTARGFI-----CKCPAGFEGATCENDARTCGSLR-CLNGGTCI-SG 1366
Query: 1435 AGASTCACAAGYSGNGIFCSEVDPCAHGH-----GGCSPHANCTKVAPGQRTCTCQDGYM 1489
+ TC C ++G PC G+ G C P T +P R C C +
Sbjct: 1367 PRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEP----TSESPFYR-CLCPAKF- 1420
Query: 1490 GDGELCQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELL---DPCSK 1546
+G LC ++ GG IP + +C E G + C L C
Sbjct: 1421 -NGLLCHILDYSF--GGGA---GRDIPPPLIEEACELPECQEDAGNKVCSLQCNNHACGW 1474
Query: 1547 NNGGCS-----PYATC-------KSTGDGQRTCTCDTAHTVGDGLTCRARVG 1586
+ G CS P+ C K DG C++A + DG C+ G
Sbjct: 1475 DGGDCSLNFNDPWKNCTQSLQCWKYFSDGHCDSQCNSAGCLFDGFDCQRAEG 1526
Score = 50.8 bits (120), Expect = 2e-05
Identities = 63/273 (23%), Positives = 85/273 (31%), Gaps = 70/273 (25%)
Query: 1958 SCCPGHYGSECQACPGGP-SSPCSDRGV--CMDGMSGSGQCLCRSGFAGTACELCAPGAF 2014
+C PG G C+ S+PC RG C+ ++ C CR+G G CE G
Sbjct: 1254 TCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDF-HCECRAGHTGRRCESVINGCK 1312
Query: 2015 GPHCQ---------------ACRCTV---HGRCDEGLGGSGSCFCDEGWT---GPRCEVQ 2053
G C+ C+C C+ GS C G T GPR
Sbjct: 1313 GKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTC 1372
Query: 2054 LELQPVCTPPC--APEAVCRAGNSC---------------ECSLGYEGDGRVCTVADLCQ 2096
L L P P C + C GN C C + +G +C + D
Sbjct: 1373 LCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSF 1432
Query: 2097 DGHGG----------CSEHANCSQVGTMVTCTCLPDYEGDGW--------------SCRA 2132
G G E C + C+ + GW +C
Sbjct: 1433 GGGAGRDIPPPLIEEACELPECQEDAGNKVCSLQCNNHACGWDGGDCSLNFNDPWKNCTQ 1492
Query: 2133 RNPC----TDGHRGGCSEHANCLSTGLNTRRCE 2161
C +DGH A CL G + +R E
Sbjct: 1493 SLQCWKYFSDGHCDSQCNSAGCLFDGFDCQRAE 1525
Score = 47.4 bits (111), Expect = 2e-04
Identities = 57/208 (27%), Positives = 74/208 (35%), Gaps = 42/208 (20%)
Query: 189 GPHCDQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQGSECRAPNPCWPSPCSLLAQCS 248
GP C Q C +C A + C+ G G C+ PNPC +PC C
Sbjct: 21 GPRCSQPGETCLN-----GGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCH 75
Query: 249 -VSPKGQAQCHCPENYHGDGMVCL-PKD------PCTDNLGGCPSNSTLCVYQKPGQAFC 300
V +G A C G +CL P D PC + GG TL Y+ C
Sbjct: 76 VVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRN--GGTCDLLTLTEYK------C 127
Query: 301 TCRPGLVSINSNASAGCFA-------FCSPFSCDRSATCQVTADGKTSCVCRE--SEVGD 351
C PG + + C + C PF C + G T CR+ +E G
Sbjct: 128 RCPPGWSGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPT---CRQDVNECGQ 184
Query: 352 --GRACYGHLLHE-------VQKATQTG 370
G +G H V +AT TG
Sbjct: 185 KPGLCRHGGTCHNEVGSYRCVCRATHTG 212
Score = 46.2 bits (108), Expect = 4e-04
Identities = 58/239 (24%), Positives = 77/239 (32%), Gaps = 63/239 (26%)
Query: 664 GSCVDCQALNTSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKGCASYCNQTIMEQGCCKG 723
G+CVD + TCPP V C+G
Sbjct: 1242 GTCVDQVGGYSCTCPPGFV-----------------------------------GERCEG 1266
Query: 724 FFGPDCTQCPGGFSNPCYGKG--NCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQCQ 781
D +C SNPC +G NC + + C C + G C N K G+ C+
Sbjct: 1267 ----DVNEC---LSNPCDARGTQNCVQRV-NDFHCECRAGHTGRRCESVINGCK-GKPCK 1317
Query: 782 EDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQE 841
C + G +C+ C GF G C CG + C C+S
Sbjct: 1318 NGGTCA---VASNTARGFICK---CPAGFEGATCENDARTCG----SLRCLNGGTCISGP 1367
Query: 842 GVARCRCLDGFEGDGFSCTPSNPCSHPDRGG--CSENAECVPGSLGT-HHCTCHKGWSG 897
C CL F G S+PC GG C C P S + C C ++G
Sbjct: 1368 RSPTCLCLGPFTGPECQFPASSPC----LGGNPCYNQGTCEPTSESPFYRCLCPAKFNG 1422
Score = 42.7 bits (99), Expect = 0.005
Identities = 53/195 (27%), Positives = 71/195 (36%), Gaps = 49/195 (25%)
Query: 720 CCKGFFGPDC-----TQCPGGFSNPCYGKGNCSDGIQGNG-ACLCFPDYKGIACHICSNP 773
C F GP+C + C GG NPCY +G C + CLC + G+ CHI
Sbjct: 1374 CLGPFTGPECQFPASSPCLGG--NPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYS 1431
Query: 774 NKHG----------------EQCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFC-- 815
G +CQED G + +C + C C G+ G C
Sbjct: 1432 FGGGAGRDIPPPLIEEACELPECQEDAG--NKVCSLQ------CNNHAC--GWDGGDCSL 1481
Query: 816 --NESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFE---GDGFSCTP--SNPC-SH 867
N+ +C + C SQ A C DGF+ +G C P C H
Sbjct: 1482 NFNDPWKNCTQSLQCWKYFSDGHCDSQCNSAGC-LFDGFDCQRAEG-QCNPLYDQYCKDH 1539
Query: 868 PDRGGCSE---NAEC 879
G C + +AEC
Sbjct: 1540 FSDGHCDQGCNSAEC 1554
Score = 42.0 bits (97), Expect = 0.008
Identities = 39/127 (30%), Positives = 51/127 (40%), Gaps = 24/127 (18%)
Query: 865 CSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGRVCVAIDECELDMRGGCHTDALCSY 924
CS P C +C + GT C C G + G C + C + C C
Sbjct: 24 CSQPGET-CLNGGKCEAAN-GTEACVC--GGAFVGPRCQDPNPC---LSTPCKNAGTCHV 76
Query: 925 V---GPGQSRCTCKLGFAGDGYQCSPID------PCRAGNGGCHGLATCRAVGGGQRVCT 975
V G C+C LGF+G +P+D PCR NGG TC + + C
Sbjct: 77 VDRRGVADYACSCALGFSGP-LCLTPLDNACLTNPCR--NGG-----TCDLLTLTEYKCR 128
Query: 976 CPPGFGG 982
CPPG+ G
Sbjct: 129 CPPGWSG 135
Score = 40.8 bits (94), Expect = 0.017
Identities = 67/299 (22%), Positives = 89/299 (29%), Gaps = 59/299 (19%)
Query: 1319 DCCPGFFGTLCEPCPGGLGGV-CSGHGQCQ--DRFLGSGECHCHEGFHGTACEVCELGRY 1375
+C G G CE G G C G C C C GF G CE
Sbjct: 1294 ECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCE-----ND 1348
Query: 1376 GPNCTGVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQC--PRKCDPNANCVQD 1433
C + G C G + +C+C + G C +SP C C C
Sbjct: 1349 ARTCGSLRCLNGGTCISGPRSP-TCLCLGPFTGPECQFPASSP-CLGGNPCYNQGTCEPT 1406
Query: 1434 SAGA-STCACAAGYSGNGIFCSEVDPCAHGHGG----------------CSPHA------ 1470
S C C A + NG+ C +D G G C A
Sbjct: 1407 SESPFYRCLCPAKF--NGLLCHILDYSFGGGAGRDIPPPLIEEACELPECQEDAGNKVCS 1464
Query: 1471 -NCTKVAPGQRTCTCQDGYMGDGELCQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREG 1529
C A G C + + C + C + H ++C G +G
Sbjct: 1465 LQCNNHACGWDGGDCSLNFNDPWKNCTQSLQCWKYFSDGHCDSQCNSAG------CLFDG 1518
Query: 1530 YSGDGIRTCELLDPCSKNNGGCSPY--ATCKS-TGDGQRTCTCDTAHTVGDGLTCRARV 1585
+ C + G C+P CK DG C++A DGL C V
Sbjct: 1519 FD------------CQRAEGQCNPLYDQYCKDHFSDGHCDQGCNSAECEWDGLDCAEHV 1565
>gi|188528675 slit homolog 1 [Homo sapiens]
Length = 1534
Score = 97.1 bits (240), Expect = 2e-19
Identities = 79/256 (30%), Positives = 102/256 (39%), Gaps = 23/256 (8%)
Query: 1951 VTTTWKPSCCPGHYGSECQA-CPGGPSSPCSDRGVCMDGMSGSGQCLCRSGFAGTACELC 2009
+TT K C G QA C SSPC ++G C + +C C SG+ G CE+
Sbjct: 905 LTTPAKKFECQGPPTLAVQAKCDLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVS 964
Query: 2010 APGAFGPHCQACRCTVHGRC--DEGLGGSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPE 2067
C + C G C EG +C C G+ GP C V + CA
Sbjct: 965 LDS-----CSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVNTD--DCVDHACANG 1017
Query: 2068 AVCRAG---NSCECSLGYEGDGRVC-TVADLCQDGHGGCSEHANCSQVGTMVTCTCLPDY 2123
VC G +C+C L YE G+ C + DLC C A C C C+P Y
Sbjct: 1018 GVCVDGVGNYTCQCPLQYE--GKACEQLVDLCSPDLNPCQHEAQCVGTPDGPRCECMPGY 1075
Query: 2124 EGDGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGDGLQCLEESEPPVDR 2183
GD S ++ C D HR C A C+ +N+ C C GY G + P
Sbjct: 1076 AGDNCS-ENQDDCRD-HR--CQNGAQCMDE-VNSYSCLCAEGYSGQLCEIPPHLPAPKSP 1130
Query: 2184 CLGQPPPCHSDAMCTD 2199
C G C + A C D
Sbjct: 1131 CEG--TECQNGANCVD 1144
Score = 85.1 bits (209), Expect = 8e-16
Identities = 75/252 (29%), Positives = 94/252 (37%), Gaps = 35/252 (13%)
Query: 1329 CEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCTGVCDCAHG 1388
C+ C L C G C + L C C G+ G CEV +G C+ G
Sbjct: 926 CDLC---LSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEV----SLDSCSSGPCENG-G 977
Query: 1389 LC--QEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTCACAAGY 1446
C QEG +C C G++G C + + C N D G TC C Y
Sbjct: 978 TCHAQEGEDAPFTCSCPTGFEGPTCG--VNTDDCVDHACANGGVCVDGVGNYTCQCPLQY 1035
Query: 1447 SGNGIFCSE-VDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQE-INSCLIH 1504
G C + VD C+ C A C G R C C GY GD C E + C H
Sbjct: 1036 EGKA--CEQLVDLCSPDLNPCQHEAQCVGTPDGPR-CECMPGYAGDN--CSENQDDCRDH 1090
Query: 1505 HGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCEL-------LDPCSKNNGGCSPYATC 1557
C A+C+ SC C EGYSG + CE+ PC C A C
Sbjct: 1091 R--CQNGAQCMDE-VNSYSCLCAEGYSG---QLCEIPPHLPAPKSPCEGTE--CQNGANC 1142
Query: 1558 KSTGDGQRTCTC 1569
G+ + C C
Sbjct: 1143 VDQGN-RPVCQC 1153
Score = 80.5 bits (197), Expect = 2e-14
Identities = 76/266 (28%), Positives = 100/266 (37%), Gaps = 45/266 (16%)
Query: 731 QCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQCQEDCGCVHGL 790
+C S+PC +G C + C C YKG C + + C G
Sbjct: 925 KCDLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLD------------SCSSGP 972
Query: 791 CDNRPGSGGVC--QQG-------TCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQE 841
C+N GG C Q+G +C GF G C + DC + C CV
Sbjct: 973 CEN----GGTCHAQEGEDAPFTCSCPTGFEGPTCGVNTDDC----VDHACANGGVCVDGV 1024
Query: 842 GVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGRV 901
G C+C +EG +C PD C A+CV G+ C C G++GD
Sbjct: 1025 GNYTCQCPLQYEGK--ACEQLVDLCSPDLNPCQHEAQCV-GTPDGPRCECMPGYAGDN-C 1080
Query: 902 CVAIDECELDMRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQC-----SPIDPCRAGNG 956
D+C D R C A C S C C G++G + +P PC
Sbjct: 1081 SENQDDCR-DHR--CQNGAQCMDEVNSYS-CLCAEGYSGQLCEIPPHLPAPKSPCEGTE- 1135
Query: 957 GCHGLATCRAVGGGQRVCTCPPGFGG 982
C A C G + VC C PGFGG
Sbjct: 1136 -CQNGANC-VDQGNRPVCQCLPGFGG 1159
Score = 74.7 bits (182), Expect = 1e-12
Identities = 63/230 (27%), Positives = 84/230 (36%), Gaps = 60/230 (26%)
Query: 1946 CHRNCVTTTWKPSCCPGHYGSECQACPGGPSS-PCSDRGVC--MDGMSGSGQCLCRSGFA 2002
CH N ++ +C G+ G +C+ SS PC + G C +G C C +GF
Sbjct: 940 CH-NDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDAPFTCSCPTGFE 998
Query: 2003 GTACELCAPGAFGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPVCTP 2062
G C G C C G C +G+G +C C + G CE +L +C+P
Sbjct: 999 GPTC-----GVNTDDCVDHACANGGVCVDGVGNY-TCQCPLQYEGKACE---QLVDLCSP 1049
Query: 2063 ---PCAPEAVCRA---GNSCECSLGYEGDG---------------------RVCTVADLC 2095
PC EA C G CEC GY GD V + + LC
Sbjct: 1050 DLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEVNSYSCLC 1109
Query: 2096 QDGHGG--------------------CSEHANCSQVGTMVTCTCLPDYEG 2125
+G+ G C ANC G C CLP + G
Sbjct: 1110 AEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPVCQCLPGFGG 1159
Score = 74.7 bits (182), Expect = 1e-12
Identities = 65/228 (28%), Positives = 86/228 (37%), Gaps = 37/228 (16%)
Query: 55 CPSGWLRELPDQITQDCRYEVQLGGSMVSMSG--CRRKCRKQVVQKACCP-GYWGSRC-- 109
CPSG+ +DC + S +G C + + CP G+ G C
Sbjct: 952 CPSGYKG-------RDCEVSLDSCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGV 1004
Query: 110 --HECPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPD---CQSVC 164
+C A C G C+DG+ N TC C + G AC++ D PD CQ
Sbjct: 1005 NTDDCVDHA---CANGGVCVDGVG-NYTCQCPLQYEGKACEQLVD--LCSPDLNPCQHEA 1058
Query: 165 SCVHGVCNHGPRGDGSCLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAPSCRCLPGYT 224
CV GPR C C GY G +C + C++ RC QC E S CL
Sbjct: 1059 QCVG--TPDGPR----CECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEVNSYSCLCAEG 1112
Query: 225 QQGSECRAP-------NPCWPSPCSLLAQCSVSPKGQAQCHCPENYHG 265
G C P +PC + C A C V + C C + G
Sbjct: 1113 YSGQLCEIPPHLPAPKSPCEGTECQNGANC-VDQGNRPVCQCLPGFGG 1159
Score = 69.3 bits (168), Expect = 5e-11
Identities = 66/245 (26%), Positives = 85/245 (34%), Gaps = 58/245 (23%)
Query: 107 SRCHECPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGP-------- 158
++C C +PC GTC + C C ++G C+ D GP
Sbjct: 924 AKCDLC---LSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCH 980
Query: 159 -----DCQSVCSCV-----------------HGVCNHGPRGDG----SCLCFAGYTGPHC 192
D CSC H N G DG +C C Y G C
Sbjct: 981 AQEGEDAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKAC 1040
Query: 193 DQELPVCQ-ELR-CPQNTQC--SAEAPSCRCLPGYTQQGSEC-RAPNPCWPSPCSLLAQC 247
+Q + +C +L C QC + + P C C+PGY G C + C C AQC
Sbjct: 1041 EQLVDLCSPDLNPCQHEAQCVGTPDGPRCECMPGYA--GDNCSENQDDCRDHRCQNGAQC 1098
Query: 248 SVSPKGQAQCHCPENYHGDGMVC-------LPKDPCTDNLGGCPSNSTLCVYQKPGQAFC 300
+ C C E Y G +C PK PC G N CV Q + C
Sbjct: 1099 -MDEVNSYSCLCAEGY--SGQLCEIPPHLPAPKSPCE---GTECQNGANCVDQ-GNRPVC 1151
Query: 301 TCRPG 305
C PG
Sbjct: 1152 QCLPG 1156
Score = 68.9 bits (167), Expect = 6e-11
Identities = 40/121 (33%), Positives = 52/121 (42%), Gaps = 12/121 (9%)
Query: 1385 CAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTCACAA 1444
C HG+CQ C C GW GL CDQ P KC + CV A + +C C
Sbjct: 1347 CLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHKC-VHGQCVPLDALSYSCQCQD 1405
Query: 1445 GYSGNGIFCSE----VDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINS 1500
GYS G C++ +PC G H +C C C G+ GELC++ +
Sbjct: 1406 GYS--GALCNQAGALAEPC---RGLQCLHGHCQASGTKGAHCVCDPGF--SGELCEQESE 1458
Query: 1501 C 1501
C
Sbjct: 1459 C 1459
Score = 63.2 bits (152), Expect = 3e-09
Identities = 59/213 (27%), Positives = 76/213 (35%), Gaps = 21/213 (9%)
Query: 149 ECQDPNRFGPD-----CQSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQELPVCQELR 203
ECQ P C S G C++ P C C +GY G C+ L C
Sbjct: 913 ECQGPPTLAVQAKCDLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGP 972
Query: 204 CPQNTQCSA----EAP-SCRCLPGYTQQGSECRA-PNPCWPSPCSLLAQCSVSPKGQAQC 257
C C A +AP +C C G+ +G C + C C+ C V G C
Sbjct: 973 CENGGTCHAQEGEDAPFTCSCPTGF--EGPTCGVNTDDCVDHACANGGVC-VDGVGNYTC 1029
Query: 258 HCPENYHGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPGLVSINSNASAGC 317
CP Y G L D C+ +L C + CV G C C PG N + +
Sbjct: 1030 QCPLQYEGKACEQL-VDLCSPDLNPC-QHEAQCVGTPDGPR-CECMPGYAGDNCSENQD- 1085
Query: 318 FAFCSPFSCDRSATCQVTADGKTSCVCRESEVG 350
C C A C + SC+C E G
Sbjct: 1086 --DCRDHRCQNGAQCMDEVN-SYSCLCAEGYSG 1115
Score = 56.2 bits (134), Expect = 4e-07
Identities = 38/122 (31%), Positives = 52/122 (42%), Gaps = 9/122 (7%)
Query: 1320 CCPGFFGTLCE-PCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPN 1378
C G+ G C+ P G G HGQC S C C +G+ G C + G
Sbjct: 1364 CEAGWVGLHCDQPADGPCHGHKCVHGQCVPLDALSYSCQCQDGYSGALCN--QAGALAEP 1421
Query: 1379 CTGVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGAS 1438
C G+ C HG CQ CVC+ G+ G C+Q+ +C + DP + Q G +
Sbjct: 1422 CRGL-QCLHGHCQASGTKGAHCVCDPGFSGELCEQE---SEC--RGDPVRDFHQVQRGYA 1475
Query: 1439 TC 1440
C
Sbjct: 1476 IC 1477
Score = 55.5 bits (132), Expect = 7e-07
Identities = 36/128 (28%), Positives = 56/128 (43%), Gaps = 14/128 (10%)
Query: 786 CVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNE-SMGDCGPTGLAQHCHLHARCVSQEGVA 844
C+HG+C G +C C G+ G C++ + G C H +H +CV + ++
Sbjct: 1347 CLHGICQPNATPGPMCH---CEAGWVGLHCDQPADGPC-----HGHKCVHGQCVPLDALS 1398
Query: 845 -RCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGRVCV 903
C+C DG+ G C + + P RG + C HC C G+SG+ +C
Sbjct: 1399 YSCQCQDGY--SGALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSGE--LCE 1454
Query: 904 AIDECELD 911
EC D
Sbjct: 1455 QESECRGD 1462
Score = 54.3 bits (129), Expect = 2e-06
Identities = 68/267 (25%), Positives = 87/267 (32%), Gaps = 63/267 (23%)
Query: 1935 LWGRPQGLG-RGCHRNC---------VTTTWKPSCCPGHYGSECQACPGGPSSPCSDRGV 1984
LW G G GC RN T KP PG C+ C C G+
Sbjct: 1301 LWQILNGTGFHGCIRNLYINNELQDFTKTQMKPGVVPG-----CEPCR---KLYCL-HGI 1351
Query: 1985 CMDGMSGSGQCLCRSGFAGTACELCAPGAFGPHCQACRCTVHGRCDEGLGGSGSCFCDEG 2044
C + C C +G+ G C+ A G C +C VHG+C S SC C +G
Sbjct: 1352 CQPNATPGPMCHCEAGWVGLHCDQPADGP----CHGHKC-VHGQCVPLDALSYSCQCQDG 1406
Query: 2045 WTGPRCEVQLELQPVCTPPCAPEAVCRA----GNSCECSLGYEGDGRVCTVADLC----- 2095
++G C L C C+A G C C G+ G+ +C C
Sbjct: 1407 YSGALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSGE--LCEQESECRGDPV 1464
Query: 2096 QDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWSCRARNPCTDGHRGGCSEHANCLSTGL 2155
+D H +A C + C RG C C L
Sbjct: 1465 RDFHQVQRGYAICQTTRPLSWVEC---------------------RGSCPGQGCCQGLRL 1503
Query: 2156 NTRR--CECHAGYVGDGLQCLEESEPP 2180
R+ EC DG EE E P
Sbjct: 1504 KRRKFTFEC-----SDGTSFAEEVEKP 1525
Score = 51.6 bits (122), Expect = 1e-05
Identities = 37/119 (31%), Positives = 49/119 (41%), Gaps = 14/119 (11%)
Query: 166 CVHGVCNHGPRGDGSCLCFAGYTGPHCDQELP-VCQELRCPQNTQC---SAEAPSCRCLP 221
C+HG+C C C AG+ G HCDQ C +C QC A + SC+C
Sbjct: 1347 CLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHKCVHG-QCVPLDALSYSCQCQD 1405
Query: 222 GYTQQGSECR----APNPCWPSPCSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPC 276
GY+ G+ C PC C L C S A C C + G+ +C + C
Sbjct: 1406 GYS--GALCNQAGALAEPCRGLQC-LHGHCQASGTKGAHCVCDPGFSGE--LCEQESEC 1459
Score = 51.2 bits (121), Expect = 1e-05
Identities = 37/123 (30%), Positives = 49/123 (39%), Gaps = 17/123 (13%)
Query: 1424 CDPNANCVQDSAGASTCACAAGYSGNGIFCSE-VDPCAHGHGGCSPHANCTKVAPGQRTC 1482
C PNA C C AG+ G + C + D HGH H C + +C
Sbjct: 1352 CQPNAT------PGPMCHCEAGWVG--LHCDQPADGPCHGHK--CVHGQCVPLDALSYSC 1401
Query: 1483 TCQDGYMGDGELCQEINSCLIHHGGCH-IHAECIPTGPQQVSCSCREGYSGDGIRTCELL 1541
CQDGY G LC + + G +H C +G + C C G+SG+ CE
Sbjct: 1402 QCQDGY--SGALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSGE---LCEQE 1456
Query: 1542 DPC 1544
C
Sbjct: 1457 SEC 1459
Score = 49.7 bits (117), Expect = 4e-05
Identities = 41/144 (28%), Positives = 53/144 (36%), Gaps = 19/144 (13%)
Query: 1318 PDCCPGFFGTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGP 1377
P PG CEPC + HG CQ CHC G+ G C+ G
Sbjct: 1333 PGVVPG-----CEPCRK----LYCLHGICQPNATPGPMCHCEAGWVGLHCDQPADG---- 1379
Query: 1378 NCTGVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQ--KITSPQCPRKCDPNANCVQDSA 1435
C G C HG C SC C G+ G C+Q + P +C + +C
Sbjct: 1380 PCHG-HKCVHGQCVPLDALSYSCQCQDGYSGALCNQAGALAEPCRGLQC-LHGHCQASGT 1437
Query: 1436 GASTCACAAGYSGNGIFCSEVDPC 1459
+ C C G+SG C + C
Sbjct: 1438 KGAHCVCDPGFSGE--LCEQESEC 1459
Score = 48.5 bits (114), Expect = 8e-05
Identities = 41/145 (28%), Positives = 58/145 (40%), Gaps = 11/145 (7%)
Query: 843 VARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGRVC 902
V RC C G++G + + S P G + +A+ G C+C G+ +G C
Sbjct: 947 VYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQ--EGEDAPFTCSCPTGF--EGPTC 1002
Query: 903 -VAIDECELDMRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHGL 961
V D+C + C +C G G C C L + G + +D C C
Sbjct: 1003 GVNTDDC---VDHACANGGVC-VDGVGNYTCQCPLQYEGKACE-QLVDLCSPDLNPCQHE 1057
Query: 962 ATCRAVGGGQRVCTCPPGFGGDGFS 986
A C G R C C PG+ GD S
Sbjct: 1058 AQCVGTPDGPR-CECMPGYAGDNCS 1081
Score = 48.1 bits (113), Expect = 1e-04
Identities = 35/112 (31%), Positives = 46/112 (41%), Gaps = 8/112 (7%)
Query: 1950 CVTTTWKP--SCCPGHYGSECQACPGG-PSSPCSDRGVCMDGMSGSGQCLCRSGFAGTAC 2006
CV T P C PG+ G C C + CMD ++ S CLC G++G C
Sbjct: 1060 CVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEVN-SYSCLCAEGYSGQLC 1118
Query: 2007 ELCA--PGAFGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLEL 2056
E+ P P C+ C C + G C C G+ GP CE L +
Sbjct: 1119 EIPPHLPAPKSP-CEGTECQNGANCVDQ-GNRPVCQCLPGFGGPECEKLLSV 1168
Score = 48.1 bits (113), Expect = 1e-04
Identities = 33/109 (30%), Positives = 48/109 (44%), Gaps = 13/109 (11%)
Query: 1463 HGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINSCLIHHGGCHIHAECIPTGPQQV 1522
HG C P+A PG C C+ G++G C + H C +H +C+P
Sbjct: 1349 HGICQPNAT-----PGPM-CHCEAGWVGLH--CDQPADGPCHGHKC-VHGQCVPLDALSY 1399
Query: 1523 SCSCREGYSGDGIRTC-ELLDPCSKNNGGCSPYATCKSTGDGQRTCTCD 1570
SC C++GYSG L +PC G + C+++G C CD
Sbjct: 1400 SCQCQDGYSGALCNQAGALAEPC---RGLQCLHGHCQASGTKGAHCVCD 1445
Score = 47.0 bits (110), Expect = 2e-04
Identities = 31/110 (28%), Positives = 48/110 (43%), Gaps = 23/110 (20%)
Query: 100 CCPGYWGSRCHECPGGA-ETPCNGHGTCLDGMDRNGTCVCQENFRGSACQ---------- 148
C PGY G C E + C C+D ++ + +C+C E + G C+
Sbjct: 1071 CMPGYAGDNCSENQDDCRDHRCQNGAQCMDEVN-SYSCLCAEGYSGQLCEIPPHLPAPKS 1129
Query: 149 ECQDPNRFGPDCQSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQELPV 198
C+ G +CQ+ +CV + G R C C G+ GP C++ L V
Sbjct: 1130 PCE-----GTECQNGANCV----DQGNRP--VCQCLPGFGGPECEKLLSV 1168
Score = 47.0 bits (110), Expect = 2e-04
Identities = 38/119 (31%), Positives = 50/119 (42%), Gaps = 17/119 (14%)
Query: 123 HGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHGVCNHGPRGDGSCL 182
HG C C C+ + G C + D GP C CVHG C SC
Sbjct: 1349 HGICQPNATPGPMCHCEAGWVGLHCDQPAD----GP-CHG-HKCVHGQCVPLDALSYSCQ 1402
Query: 183 CFAGYTGPHCDQE---LPVCQELRCPQNTQCSA---EAPSCRCLPGYT----QQGSECR 231
C GY+G C+Q C+ L+C + C A + C C PG++ +Q SECR
Sbjct: 1403 CQDGYSGALCNQAGALAEPCRGLQC-LHGHCQASGTKGAHCVCDPGFSGELCEQESECR 1460
Score = 46.2 bits (108), Expect = 4e-04
Identities = 34/122 (27%), Positives = 46/122 (37%), Gaps = 12/122 (9%)
Query: 744 GNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQCQEDCGCVHGLCDNRPGSGGVCQQ 803
G C C C + G+ C ++ HG +C VHG C CQ
Sbjct: 1350 GICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHKC------VHGQCVPLDALSYSCQ- 1402
Query: 804 GTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGDGFSCTPSN 863
C G+SG CN++ P Q H H + +G A C C GF G+ C +
Sbjct: 1403 --CQDGYSGALCNQAGALAEPCRGLQCLHGHCQASGTKG-AHCVCDPGFSGE--LCEQES 1457
Query: 864 PC 865
C
Sbjct: 1458 EC 1459
Score = 42.4 bits (98), Expect = 0.006
Identities = 33/110 (30%), Positives = 44/110 (40%), Gaps = 17/110 (15%)
Query: 55 CPSGWLRELPDQITQD-CRYEVQLGGSMVSMSGCRRKCRKQVVQKACCPGYWGSRCHECP 113
C +GW+ DQ C + G V + C+ C GY G+ C++
Sbjct: 1364 CEAGWVGLHCDQPADGPCHGHKCVHGQCVPLDALSYSCQ-------CQDGYSGALCNQAG 1416
Query: 114 GGAETPCNG----HGTCLDGMDRNGTCVCQENFRGSACQ---ECQ-DPNR 155
AE PC G HG C + CVC F G C+ EC+ DP R
Sbjct: 1417 ALAE-PCRGLQCLHGHCQASGTKGAHCVCDPGFSGELCEQESECRGDPVR 1465
Score = 40.4 bits (93), Expect = 0.023
Identities = 41/140 (29%), Positives = 52/140 (37%), Gaps = 30/140 (21%)
Query: 865 CSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGRVCVAIDECELDMRGGCH----TDA 920
C H G C NA PG + C C GW G C+ G CH
Sbjct: 1347 CLH---GICQPNA--TPGPM----CHCEAGWVGL--------HCDQPADGPCHGHKCVHG 1389
Query: 921 LCSYVGPGQSRCTCKLGFAGD--GYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPP 978
C + C C+ G++G + +PCR G HG C+A G C C P
Sbjct: 1390 QCVPLDALSYSCQCQDGYSGALCNQAGALAEPCR-GLQCLHG--HCQASGTKGAHCVCDP 1446
Query: 979 GFGGD----GFSCYGDIFRE 994
GF G+ C GD R+
Sbjct: 1447 GFSGELCEQESECRGDPVRD 1466
Score = 37.7 bits (86), Expect = 0.15
Identities = 29/107 (27%), Positives = 39/107 (36%), Gaps = 8/107 (7%)
Query: 846 CRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGRVCVAI 905
C C G+ G C P P G + +CVP ++ C C G+S G +C
Sbjct: 1362 CHCEAGWVG--LHC--DQPADGPCHGHKCVHGQCVPLDALSYSCQCQDGYS--GALCNQA 1415
Query: 906 DECELDMRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCR 952
RG C G + C C GF+G+ C CR
Sbjct: 1416 GALAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSGE--LCEQESECR 1460
>gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]
Length = 4242
Score = 95.9 bits (237), Expect = 5e-19
Identities = 106/381 (27%), Positives = 140/381 (36%), Gaps = 114/381 (29%)
Query: 1275 CTRRFRCTQGFQLQDTPRKSCVYRSGFSF----SRGCSYTCAKKIQVPD----CCPGFFG 1326
C++R RC G CV G++ +R C + C + + D C PG+ G
Sbjct: 315 CSQRGRCKDG---------RCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTG 365
Query: 1327 TLCEP--CPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEV------------CEL 1372
C CP C G G+C+D GEC C G+ G C V CE
Sbjct: 366 EDCSTRTCPRD----CRGRGRCED-----GECICDTGYSGDDCGVRSCPGDCNQRGRCED 416
Query: 1373 GRY--GPNCTGVCDCAHGLCQEGLQG-----DGSCVCNVGWQGLRCDQKITSPQCPRKCD 1425
GR P TG DC C +G +G CVCN G+ G C + CP C
Sbjct: 417 GRCVCWPGYTGT-DCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVR----SCPGDCR 471
Query: 1426 PNANCVQDSAGASTCACAAGYSGNGI-------FCSEVDPCAHGHGGCSP---HANC-TK 1474
C + C C GY+G C C G C+P +C ++
Sbjct: 472 GRGRC-----ESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSR 526
Query: 1475 VAPG---------QRTCTCQDGYMGDGELCQEINSCLIHHGGCHIHAECIPTGPQQVSCS 1525
PG C C GY GE C SC GGC +C+ C
Sbjct: 527 RCPGDCRGHGLCEDGVCVCDAGY--SGEDC-STRSC---PGGCRGRGQCL-----DGRCV 575
Query: 1526 CREGYSGD--GIRTCELLDPCSKN----NGGC----------SPYATCKSTGDG-----Q 1564
C +GYSG+ G+R C + CS++ +G C TC S G +
Sbjct: 576 CEDGYSGEDCGVRQCP--NDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEE 633
Query: 1565 RTCTCDTAHTVGDGLTCRARV 1585
C CD +T G TC R+
Sbjct: 634 GRCLCDPGYT---GPTCATRM 651
Score = 93.2 bits (230), Expect = 3e-18
Identities = 88/311 (28%), Positives = 110/311 (35%), Gaps = 76/311 (24%)
Query: 1274 NCTRRFRCTQGFQLQDTPRKSCVYRSGFS----FSRGCSYTCAKKIQVPD----CCPGFF 1325
+C R RC QG CV R+GFS R C C+++ + C PG+
Sbjct: 221 DCQGRGRCVQGV---------CVCRAGFSGPDCSQRSCPRGCSQRGRCEGGRCVCDPGYT 271
Query: 1326 GTLC--EPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCTGVC 1383
G C CP G CS G+C++ G C C+ G+ G C GV
Sbjct: 272 GDDCGMRSCPRG----CSQRGRCEN-----GRCVCNPGYTGEDC-------------GVR 309
Query: 1384 DCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTCACA 1443
C G Q G DG CVC+ G+ G C + CP C CV C C
Sbjct: 310 SCPRGCSQRGRCKDGRCVCDPGYTGEDCGTR----SCPWDCGEGGRCVD-----GRCVCW 360
Query: 1444 AGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINSCLI 1503
GY+G G G C C C GY GD C + SC
Sbjct: 361 PGYTGEDCSTRTCPRDCRGRGRCE-----------DGECICDTGYSGDD--C-GVRSC-- 404
Query: 1504 HHGGCHIHAECIPTGPQQVSCSCREGYSGD--GIRTC--ELLDPCSKNNGGCSPYATCKS 1559
G C+ C + C C GY+G G R C + NG C A
Sbjct: 405 -PGDCNQRGRC-----EDGRCVCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSG 458
Query: 1560 TGDGQRTCTCD 1570
G R+C D
Sbjct: 459 EDCGVRSCPGD 469
Score = 92.8 bits (229), Expect = 4e-18
Identities = 91/320 (28%), Positives = 114/320 (35%), Gaps = 105/320 (32%)
Query: 1274 NCTRRFRCTQGFQLQDTPRKSCVYRSGFSF----SRGCSYTCAKKIQVPD----CCPGFF 1325
+C R RC G C+ G++ +R C C + + D C PGF
Sbjct: 469 DCRGRGRCESG---------RCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFT 519
Query: 1326 GTLC--EPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACE--------------- 1368
G C CPG C GHG C+D G C C G+ G C
Sbjct: 520 GEDCGSRRCPGD----CRGHGLCED-----GVCVCDAGYSGEDCSTRSCPGGCRGRGQCL 570
Query: 1369 ----VCELGRYGPNCTGVCDCAHGLCQEGLQGDGSCVCNVGWQG---------------- 1408
VCE G G +C GV C + Q G+ DG C+C W+G
Sbjct: 571 DGRCVCEDGYSGEDC-GVRQCPNDCSQHGVCQDGVCIC---WEGYVSEDCSIRTCPSNCH 626
Query: 1409 ---------LRCDQKITSP-----QCPRKCDPNANCVQDSAGASTCACAAGYSGNGIFCS 1454
CD T P CP C CVQ C C GY G C
Sbjct: 627 GRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQ-----GVCLCHVGYGGED--CG 679
Query: 1455 EVDPCAHG-HGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINSCLIHHGGCHIHAE 1513
+ +P A GGC P C GQ C C +G+ G C I +C G C E
Sbjct: 680 QEEPPASACPGGCGPRELC---RAGQ--CVCVEGFRGPD--C-AIQTC---PGDCRGRGE 728
Query: 1514 CIPTGPQQVSCSCREGYSGD 1533
C SC C++GY+G+
Sbjct: 729 C-----HDGSCVCKDGYAGE 743
Score = 90.9 bits (224), Expect = 1e-17
Identities = 93/324 (28%), Positives = 114/324 (35%), Gaps = 86/324 (26%)
Query: 1274 NCTRRFRCTQGFQLQDTPRKSCVYRSGFSFS----RGCSYTCAKKIQVPD----CCPGFF 1325
+C R RC G CV +G+S R C C + + C PG+
Sbjct: 438 DCRGRGRCENGV---------CVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPGYT 488
Query: 1326 GTLC--EPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCTGVC 1383
G C CPG C G G+C D G C C+ GF G C C G C
Sbjct: 489 GRDCGTRACPGD----CRGRGRCVD-----GRCVCNPGFTGEDCG-------SRRCPGDC 532
Query: 1384 DCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTCACA 1443
HGLC+ DG CVC+ G+ G C + CP C C+ C C
Sbjct: 533 R-GHGLCE-----DGVCVCDAGYSGEDCSTR----SCPGGCRGRGQCLD-----GRCVCE 577
Query: 1444 AGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINSCLI 1503
GYSG C V C + CS H C C C +GY+ + + S
Sbjct: 578 DGYSGED--CG-VRQCPND---CSQHGVCQ-----DGVCICWEGYVSEDCSIRTCPSNCH 626
Query: 1504 HHGGCHI-HAECIP--TGPQ-----------------QVSCSCREGYSGDGIRTCELLDP 1543
G C C P TGP Q C C GY G+ E P
Sbjct: 627 GRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEE--PP 684
Query: 1544 CSKNNGGCSPYATCKSTGDGQRTC 1567
S GGC P C++ GQ C
Sbjct: 685 ASACPGGCGPRELCRA---GQCVC 705
Score = 89.4 bits (220), Expect = 4e-17
Identities = 75/259 (28%), Positives = 96/259 (37%), Gaps = 84/259 (32%)
Query: 1959 CCPGHYGSECQACPGGPSSP--CSDRGVCMDGMSGSGQCLCRSGFAGTAC--ELCAPGAF 2014
C PG+ G C G PS P C RG C+ G+ C+CR+GF+G C C G
Sbjct: 204 CFPGYTGPSC----GWPSCPGDCQGRGRCVQGV-----CVCRAGFSGPDCSQRSCPRG-- 252
Query: 2015 GPHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEAVCRAGN 2074
C+ GRC+ G C CD G+TG C ++ C C+ C G
Sbjct: 253 --------CSQRGRCE-----GGRCVCDPGYTGDDCGMR-----SCPRGCSQRGRCENGR 294
Query: 2075 SCECSLGYEGDG-------RVCTVADLCQDGHGGC------------SEHANCSQVGTMV 2115
C C+ GY G+ R C+ C+DG C S +C + G V
Sbjct: 295 -CVCNPGYTGEDCGVRSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCV 353
Query: 2116 --TCTCLPDYEGDGWS-------CRARNPCTDGH-----------------RGGCSEHAN 2149
C C P Y G+ S CR R C DG G C++
Sbjct: 354 DGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGR 413
Query: 2150 CLSTGLNTRRCECHAGYVG 2168
C RC C GY G
Sbjct: 414 C-----EDGRCVCWPGYTG 427
Score = 87.4 bits (215), Expect = 2e-16
Identities = 76/245 (31%), Positives = 99/245 (40%), Gaps = 54/245 (22%)
Query: 1959 CCPGHYGSEC--QACPGGPSSPCSDRGVCMDGMSGSGQCLCRSGFAGTACELCAPGAFGP 2016
C PG+ G +C +ACPG C RG C+DG +C+C GF G C G
Sbjct: 483 CWPGYTGRDCGTRACPGD----CRGRGRCVDG-----RCVCNPGFTGEDC--------GS 525
Query: 2017 HCQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEAVCRAGNSC 2076
C HG C++G+ C CD G++G C + C C C G C
Sbjct: 526 RRCPGDCRGHGLCEDGV-----CVCDAGYSGEDCSTR-----SCPGGCRGRGQCLDGR-C 574
Query: 2077 ECSLGYEGDG-------RVCTVADLCQDGHGGCSE---HANCSQVGTMVTCTCLPDYEGD 2126
C GY G+ C+ +CQDG C E +CS TC + G
Sbjct: 575 VCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCS------IRTCPSNCHGR 628
Query: 2127 GWSCRARNPCTDGHRG-GCSEH---ANCLSTGLNTRR-CECHAGYVGDGLQCLEESEPPV 2181
G R C G+ G C+ A+C G + C CH GY G+ C +E EPP
Sbjct: 629 GRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGE--DCGQE-EPPA 685
Query: 2182 DRCLG 2186
C G
Sbjct: 686 SACPG 690
Score = 85.1 bits (209), Expect = 8e-16
Identities = 87/323 (26%), Positives = 114/323 (35%), Gaps = 95/323 (29%)
Query: 691 CVYIHDPTGLNVLKKGCASYCN-QTIMEQGCC---KGFFGPDC--TQCPGGFSNPCYGKG 744
CV TG + + C C + E G C G+ G DC CPG C G+G
Sbjct: 419 CVCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGD----CRGRG 474
Query: 745 NCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQCQEDCGCVHGLCDNRPGSGGVCQQG 804
C +G C+C+P Y G C + P C+ CV G C
Sbjct: 475 RCE-----SGRCMCWPGYTGRDCGTRACPG----DCRGRGRCVDGRC------------- 512
Query: 805 TCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGDGFSCTPSNP 864
C PGF+G DCG C H C ++GV C C G+ G+ S T S P
Sbjct: 513 VCNPGFTGE-------DCGSRRCPGDCRGHGLC--EDGV--CVCDAGYSGEDCS-TRSCP 560
Query: 865 CSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDG------------------RVCVA-- 904
GGC +C+ G C C G+SG+ VC+
Sbjct: 561 ------GGCRGRGQCLDG-----RCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWE 609
Query: 905 ---IDECEL-DMRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHG 960
++C + CH C + RC C G+ G P R C G
Sbjct: 610 GYVSEDCSIRTCPSNCHGRGRCE-----EGRCLCDPGYTG------PTCATRMCPADCRG 658
Query: 961 LATCRAVGGGQRVCTCPPGFGGD 983
C Q VC C G+GG+
Sbjct: 659 RGRCV-----QGVCLCHVGYGGE 676
Score = 83.2 bits (204), Expect = 3e-15
Identities = 100/387 (25%), Positives = 128/387 (33%), Gaps = 109/387 (28%)
Query: 651 PKHCSEEQHKIVAGSCVDCQALNTSTCPPNSVKLDI------FPKECVYIHDPTGLNVLK 704
P+ CS+ + + G CV C S D CV TG +
Sbjct: 312 PRGCSQ-RGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCST 370
Query: 705 KGCASYCN-QTIMEQG---CCKGFFGPDC--TQCPGGFSNPCYGKGNCSDGIQGNGACLC 758
+ C C + E G C G+ G DC CPG C +G C DG C+C
Sbjct: 371 RTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGD----CNQRGRCEDG-----RCVC 421
Query: 759 FPDYKGIAC--HICSNPNKHGEQCQ------------EDCG--CVHGLCDNRPGSGGVCQ 802
+P Y G C C + +C+ EDCG G C R G C+
Sbjct: 422 WPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGR----GRCE 477
Query: 803 QGTCA--PGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGDGFSCT 860
G C PG++GR DCG C RCV RC C GF G+
Sbjct: 478 SGRCMCWPGYTGR-------DCGTRACPGDCRGRGRCVD----GRCVCNPGFTGEDCG-- 524
Query: 861 PSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGRVCVAIDECELDMRGGCHTDA 920
S C G C + C G C C G+SG+ D GGC
Sbjct: 525 -SRRCP----GDCRGHGLCEDGV-----CVCDAGYSGE-------DCSTRSCPGGCRGRG 567
Query: 921 LCSYVGPGQSRCTCKLGFAGDG-------YQCSPIDPCRAG------------------N 955
C RC C+ G++G+ CS C+ G
Sbjct: 568 QCL-----DGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCP 622
Query: 956 GGCHGLATCRAVGGGQRVCTCPPGFGG 982
CHG C + C C PG+ G
Sbjct: 623 SNCHGRGRCE-----EGRCLCDPGYTG 644
Score = 81.6 bits (200), Expect = 9e-15
Identities = 85/269 (31%), Positives = 100/269 (37%), Gaps = 68/269 (25%)
Query: 1328 LCEPCPGGL--GGVCSGHGQCQDRFLGSGECHCHEGFHGTACEV-CELGRYGPNCTGVCD 1384
L E C GG +G GQ R L C H F + C CE G GP C+ D
Sbjct: 117 LKEQCTGGCCPASAQAGTGQTDVRTL----CSLHGVFDLSRCTCSCEPGWGGPTCSDPTD 172
Query: 1385 C---------AHGLCQEGLQGDGSCV-----CNVGWQGLRCDQKITSPQCPRKCDPNANC 1430
A G C + G CV C G+ G C P CP C C
Sbjct: 173 AEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCGW----PSCPGDCQGRGRC 228
Query: 1431 VQDSAGASTCACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMG 1490
VQ C C AG+SG CS+ C G CS C G R C C GY G
Sbjct: 229 VQ-----GVCVCRAGFSGPD--CSQRS-CPRG---CSQRGRCE----GGR-CVCDPGYTG 272
Query: 1491 DGELCQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGD--GIRTCELLDPCSKNN 1548
D C + SC GC C + C C GY+G+ G+R+C
Sbjct: 273 DD--CG-MRSC---PRGCSQRGRC-----ENGRCVCNPGYTGEDCGVRSCP--------- 312
Query: 1549 GGCSPYATCKSTGDGQRTCTCDTAHTVGD 1577
GCS CK DG+ C CD +T D
Sbjct: 313 RGCSQRGRCK---DGR--CVCDPGYTGED 336
Score = 81.3 bits (199), Expect = 1e-14
Identities = 86/295 (29%), Positives = 105/295 (35%), Gaps = 69/295 (23%)
Query: 720 CCKGFFGPDC---TQCPGGFSNPCYGKGNCSDGI--QGN---GACLCFPDYKGIACHICS 771
C G+ GP C T S+P G+C D QG G C+CFP Y G +C S
Sbjct: 158 CEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCGWPS 217
Query: 772 NPNKHGEQCQEDCGCVHGLCDNRPG-SGGVCQQGTCAPGFSGR--------FCNESM--G 820
P CQ CV G+C R G SG C Q +C G S R C+
Sbjct: 218 CPG----DCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQRGRCEGGRCVCDPGYTGD 273
Query: 821 DCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGD--GFSCTPSNPCSHPDRGGCSENAE 878
DCG + C RC + RC C G+ G+ G P GCS+
Sbjct: 274 DCGMRSCPRGCSQRGRCEN----GRCVCNPGYTGEDCGVRSCPR---------GCSQRGR 320
Query: 879 CVPGSLGTHHCTCHKGWSGDGRVCVAIDECELDMRGGCHTDALCSYVGPGQSRCTCKLGF 938
C G C C G++G+ C D C C RC C G+
Sbjct: 321 CKDG-----RCVCDPGYTGED---CGTRSCPWD----CGEGGRCV-----DGRCVCWPGY 363
Query: 939 AGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGFGGDGF---SCYGD 990
G+ CS R C G C C C G+ GD SC GD
Sbjct: 364 TGE--DCS----TRTCPRDCRGRGRCE-----DGECICDTGYSGDDCGVRSCPGD 407
Score = 80.9 bits (198), Expect = 2e-14
Identities = 85/318 (26%), Positives = 105/318 (33%), Gaps = 105/318 (33%)
Query: 1944 RGCHRNCVTTTWKPSCCPGHYGSEC--QACPGGPSSPCSDRGVCMDGMSGSGQCLCRSGF 2001
RGC + + C PG+ G +C ++CP G CS RG C D G+C+C G+
Sbjct: 282 RGCSQRGRCENGRCVCNPGYTGEDCGVRSCPRG----CSQRGRCKD-----GRCVCDPGY 332
Query: 2002 AGTACE-------------------LCAPGAFGPHC--QAC--RCTVHGRCDEGLGGSGS 2038
G C +C PG G C + C C GRC++ G
Sbjct: 333 TGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCED-----GE 387
Query: 2039 CFCDEGWTGPRCEVQLELQPVCTPPCAPEAVCRAGNSCECSLGYEGDG-------RVCTV 2091
C CD G++G C V+ C C C G C C GY G R C
Sbjct: 388 CICDTGYSGDDCGVR-----SCPGDCNQRGRCEDGR-CVCWPGYTGTDCGSRACPRDCRG 441
Query: 2092 ADLCQDG------------------HGGCSEHANCSQVGTMVTCTCLPDYEGDG------ 2127
C++G G C C C C P Y G
Sbjct: 442 RGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCES----GRCMCWPGYTGRDCGTRAC 497
Query: 2128 -WSCRARNPCTDGH-----------------RGGCSEHANCLSTGLNTRRCECHAGYVGD 2169
CR R C DG G C H C G+ C C AGY G+
Sbjct: 498 PGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLC-EDGV----CVCDAGYSGE 552
Query: 2170 GLQCLEESEPPVDRCLGQ 2187
C S P R GQ
Sbjct: 553 --DCSTRSCPGGCRGRGQ 568
Score = 79.3 bits (194), Expect = 4e-14
Identities = 74/269 (27%), Positives = 97/269 (36%), Gaps = 74/269 (27%)
Query: 1944 RGCHRNCVTTTWKPSCCPGHYGSEC--QACPGGPSSPCSDRGVCMDGMSGSGQCLCRSGF 2001
RGC + + C PG+ G +C ++CP G CS RG C +G+C+C G+
Sbjct: 251 RGCSQRGRCEGGRCVCDPGYTGDDCGMRSCPRG----CSQRGRC-----ENGRCVCNPGY 301
Query: 2002 AGTACE-------------------LCAPGAFGPHC--QAC--RCTVHGRCDEGLGGSGS 2038
G C +C PG G C ++C C GRC + G
Sbjct: 302 TGEDCGVRSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVD-----GR 356
Query: 2039 CFCDEGWTGPRCEVQLELQPVCTPPCAPEAVCRAGNSCECSLGYEGDGRVCTVADLCQDG 2098
C C G+TG C + C C C G C C GY GD C V +
Sbjct: 357 CVCWPGYTGEDCSTR-----TCPRDCRGRGRCEDG-ECICDTGYSGDD--CGV----RSC 404
Query: 2099 HGGCSEHANCSQVGTMVTCTCLPDYEGDGW-------SCRARNPCTDG----HRGGCSEH 2147
G C++ C C C P Y G CR R C +G + G E
Sbjct: 405 PGDCNQRGRCED----GRCVCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGED 460
Query: 2148 -------ANCLSTG-LNTRRCECHAGYVG 2168
+C G + RC C GY G
Sbjct: 461 CGVRSCPGDCRGRGRCESGRCMCWPGYTG 489
Score = 75.5 bits (184), Expect = 6e-13
Identities = 74/269 (27%), Positives = 97/269 (36%), Gaps = 84/269 (31%)
Query: 1959 CCPGHYGSEC--QACPGGPSSPCSDRGVCMDGMSGSGQCLCRSGFAGTACE--------- 2007
C G+ G +C ++CPG C+ RG C DG +C+C G+ GT C
Sbjct: 390 CDTGYSGDDCGVRSCPGD----CNQRGRCEDG-----RCVCWPGYTGTDCGSRACPRDCR 440
Query: 2008 ----------LCAPGAFGPHC--QAC--RCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQ 2053
+C G G C ++C C GRC+ SG C C G+TG C +
Sbjct: 441 GRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCE-----SGRCMCWPGYTGRDCGTR 495
Query: 2054 LELQPVCTPPCAPEAVCRAGNSCECSLGYEGD---GRVCTVADLCQDGHGGCSEHANCSQ 2110
C C C G C C+ G+ G+ R C G C H C
Sbjct: 496 -----ACPGDCRGRGRCVDGR-CVCNPGFTGEDCGSRRCP---------GDCRGHGLCED 540
Query: 2111 VGTMVTCTCLPDYEGDGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGDG 2170
C C Y G+ S R+ C GGC CL RC C GY G+
Sbjct: 541 ----GVCVCDAGYSGEDCSTRS---CP----GGCRGRGQCLD-----GRCVCEDGYSGE- 583
Query: 2171 LQCLEESEPPVDRCLGQPPPCHSDAMCTD 2199
+ V +C P C +C D
Sbjct: 584 -------DCGVRQC---PNDCSQHGVCQD 602
Score = 75.5 bits (184), Expect = 6e-13
Identities = 95/377 (25%), Positives = 128/377 (33%), Gaps = 100/377 (26%)
Query: 87 CRRKCRKQVVQKACCPGYWGSRC--HECPGGAETPCNGHGTCLDGMDRNGTCVCQENFRG 144
CR + R + + C PGY G C CPG C G G C+DG CVC F G
Sbjct: 470 CRGRGRCESGRCMCWPGYTGRDCGTRACPGD----CRGRGRCVDGR-----CVCNPGFTG 520
Query: 145 SACQECQDPNRFGPDCQSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQELPVCQELRC 204
C + P DC+ HG+C DG C+C AGY+G C C
Sbjct: 521 EDCGSRRCPG----DCRG-----HGLCE-----DGVCVCDAGYSGEDCSTR-------SC 559
Query: 205 PQNTQCSAEAPSCRCLPGYTQQGSEC---RAPNPCWPSPCSLLAQCSVSPKGQAQC---- 257
P + + RC+ G +C + PN C +Q V G C
Sbjct: 560 PGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDC--------SQHGVCQDGVCICWEGY 611
Query: 258 --------HCPENYHGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPG-----QAFCTCRP 304
CP N HG G + C G + +C G Q C C
Sbjct: 612 VSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHV 671
Query: 305 GL----VSINSNASAGCFAFCSPFSCDRSATCQVTADG---------------------- 338
G ++ C C P R+ C V +G
Sbjct: 672 GYGGEDCGQEEPPASACPGGCGPRELCRAGQC-VCVEGFRGPDCAIQTCPGDCRGRGECH 730
Query: 339 KTSCVCRESEVGDG-----RACYGHLLHEVQKATQTGRVFLQLRVAVAMMD-QGCREILT 392
SCVC++ G+ G +H +++ T V + A +D + I T
Sbjct: 731 DGSCVCKDGYAGEDCGEEVPTIEGMRMHLLEETT----VRTEWTPAPGPVDAYEIQFIPT 786
Query: 393 TAG---PFTVLVPSVSS 406
T G PFT VPS +S
Sbjct: 787 TEGASPPFTARVPSSAS 803
Score = 75.1 bits (183), Expect = 8e-13
Identities = 75/279 (26%), Positives = 95/279 (34%), Gaps = 69/279 (24%)
Query: 86 GCRRKCRKQVVQKACCPGYWGSRC--HECPGGAETPCNGHGTCLDGMDRNGTCVCQENFR 143
GC ++ R + + C PGY G C CP G C+ G C NG CVC +
Sbjct: 252 GCSQRGRCEGGRCVCDPGYTGDDCGMRSCPRG----CSQRGRC-----ENGRCVCNPGYT 302
Query: 144 GSACQECQDPNRFGPDCQSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQELPVCQELR 203
G C V SC G G DG C+C GYTG C
Sbjct: 303 GEDC--------------GVRSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTR---SCPWD 345
Query: 204 CPQNTQCSAEAPSCRCLPGYTQQGSECRAPNPCWPSPCSLLAQCSVSPKGQAQCHCPENY 263
C + +C C C PGYT G +C + C P C +C +C C Y
Sbjct: 346 CGEGGRC--VDGRCVCWPGYT--GEDC-STRTC-PRDCRGRGRCE-----DGECICDTGY 394
Query: 264 HGD--GMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPGLVSINSNASAGCFAFC 321
GD G+ P D + G C C C PG + C +
Sbjct: 395 SGDDCGVRSCPGD--CNQRGRCEDGR------------CVCWPGYTGTD------CGSRA 434
Query: 322 SPFSCDRSATCQVTADGKTSCVCRESEVGDG---RACYG 357
P C C+ CVC G+ R+C G
Sbjct: 435 CPRDCRGRGRCE-----NGVCVCNAGYSGEDCGVRSCPG 468
Score = 75.1 bits (183), Expect = 8e-13
Identities = 64/231 (27%), Positives = 85/231 (36%), Gaps = 61/231 (26%)
Query: 1937 GRPQGLGRGCHRNCVTTTWKPSCCPGHYGSEC--QACPGGPSSPCSDRGVCMDGMSGSGQ 1994
G +G G+ CV C G+ G +C + CP + CS GVC DG+
Sbjct: 561 GGCRGRGQCLDGRCV-------CEDGYSGEDCGVRQCP----NDCSQHGVCQDGV----- 604
Query: 1995 CLCRSGFAGTACE-------------------LCAPGAFGPHCQACRCTV----HGRCDE 2031
C+C G+ C LC PG GP C C GRC +
Sbjct: 605 CICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQ 664
Query: 2032 GLGGSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEAVCRAGNSCECSLGYEG-DGRVCT 2090
G+ C C G+ G C + C C P +CRAG C C G+ G D + T
Sbjct: 665 GV-----CLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAG-QCVCVEGFRGPDCAIQT 718
Query: 2091 VADLCQDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWSCRARNPCTDGHR 2141
C+ G G C + +C C Y G+ C P +G R
Sbjct: 719 CPGDCR-GRGECHDG----------SCVCKDGYAGE--DCGEEVPTIEGMR 756
Score = 67.4 bits (163), Expect = 2e-10
Identities = 75/303 (24%), Positives = 103/303 (33%), Gaps = 74/303 (24%)
Query: 87 CRRKCRKQVVQKACCPGYWGSRC--HECPGGAETPCNGHGTCLDGMDRNGTCVCQENFRG 144
CR + R + + C GY G C CPG CN G C DG CVC + G
Sbjct: 377 CRGRGRCEDGECICDTGYSGDDCGVRSCPGD----CNQRGRCEDGR-----CVCWPGYTG 427
Query: 145 SACQECQDPNRFGPDCQSVCSCVHGVC--NHGPRGD-------------------GSCLC 183
+ C P DC+ C +GVC N G G+ G C+C
Sbjct: 428 TDCGSRACPR----DCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMC 483
Query: 184 FAGYTGPHCDQELPVCQELRCPQNTQCSAEAPS--CRCLPGYTQQG-------SECRAPN 234
+ GYTG C CP + + C C PG+T + +CR
Sbjct: 484 WPGYTGRDCGTR-------ACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHG 536
Query: 235 PCWPSPCSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGG-------CPSNS 287
C C + S + + CP G G + C D G CP++
Sbjct: 537 LCEDGVC--VCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDC 594
Query: 288 TLCVYQKPGQAFCTCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVTADGKTSCVCRES 347
+ + G C C G V S C P +C C+ +G+ C+C
Sbjct: 595 SQHGVCQDG--VCICWEGYV------SEDCSIRTCPSNCHGRGRCE---EGR--CLCDPG 641
Query: 348 EVG 350
G
Sbjct: 642 YTG 644
Score = 62.4 bits (150), Expect = 6e-09
Identities = 57/225 (25%), Positives = 81/225 (36%), Gaps = 72/225 (32%)
Query: 691 CVYIHDPTGLNVLKKGCASYCNQT-IMEQGCC---KGFFGPDCT--QCPGGFSNPCYGKG 744
CV +G + + C + C+Q + + G C +G+ DC+ CP C+G+G
Sbjct: 574 CVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSN----CHGRG 629
Query: 745 NCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQCQEDC----GCVHGLCDNRPGSGGV 800
C +G CLC P Y G C C DC CV G+C
Sbjct: 630 RCEEG-----RCLCDPGYTGPTCAT--------RMCPADCRGRGRCVQGVC--------- 667
Query: 801 CQQGTCAPGFSGRFCNES-------MGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFE 853
C G+ G C + G CGP L + +C C++GF
Sbjct: 668 ----LCHVGYGGEDCGQEEPPASACPGGCGPRELCR-------------AGQCVCVEGFR 710
Query: 854 GDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGD 898
G + C G C EC GS C C G++G+
Sbjct: 711 GPDCAI---QTCP----GDCRGRGECHDGS-----CVCKDGYAGE 743
Score = 61.2 bits (147), Expect = 1e-08
Identities = 82/340 (24%), Positives = 110/340 (32%), Gaps = 85/340 (25%)
Query: 43 PCTSCAAIKKQTCPSGWLRELPDQITQDCRYEVQLGGSMVSMSGCRRKCRKQVVQKACCP 102
P T C CP G + Q R +++ +V G + +C CCP
Sbjct: 81 PSTGCG------CPPGTEPPVLASEVQALRVRLEILEELVK--GLKEQCTG-----GCCP 127
Query: 103 GYWGSRCHECPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQECQD---PNRFGPD 159
++ T C+ HG + R TC C+ + G C + D P P
Sbjct: 128 A--SAQAGTGQTDVRTLCSLHGVF--DLSRC-TCSCEPGWGGPTCSDPTDAEIPPSSPPS 182
Query: 160 CQSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQEL----------------------- 196
SC + G G C+CF GYTGP C
Sbjct: 183 ASG--SCPDDCNDQGRCVRGRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFS 240
Query: 197 -PVCQELRCPQNTQCS----AEAPSCRCLPGYTQQGSECRAPNPCWPSPCSLLAQCSVSP 251
P C + CP+ CS E C C PGYT G +C C P CS +C
Sbjct: 241 GPDCSQRSCPRG--CSQRGRCEGGRCVCDPGYT--GDDC-GMRSC-PRGCSQRGRCE--- 291
Query: 252 KGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPGLVSINS 311
+C C Y G+ + CP + K G+ C C PG
Sbjct: 292 --NGRCVCNPGYTGEDC----------GVRSCPRGCSQRGRCKDGR--CVCDPGY----- 332
Query: 312 NASAGCFAFCSPFSCDRSATCQVTADGKTSCVCRESEVGD 351
C P+ C C DG+ CVC G+
Sbjct: 333 -TGEDCGTRSCPWDCGEGGRC---VDGR--CVCWPGYTGE 366
Score = 59.7 bits (143), Expect = 4e-08
Identities = 55/198 (27%), Positives = 72/198 (36%), Gaps = 47/198 (23%)
Query: 2003 GTACELCAPGAFGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQ-PVCT 2061
G C A G C++HG D +C C+ GW GP C + + P +
Sbjct: 123 GGCCPASAQAGTGQTDVRTLCSLHGVFDLS---RCTCSCEPGWGGPTCSDPTDAEIPPSS 179
Query: 2062 PP---------CAPEAVCRAGNSCECSLGY--------------EGDGRVCTVADLCQDG 2098
PP C + C G C C GY +G GR +C+ G
Sbjct: 180 PPSASGSCPDDCNDQGRCVRGR-CVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAG 238
Query: 2099 HGG--CSEHA---NCSQVGTMV--TCTCLPDYEGDGWSCRARNPCTDGHRGGCSEHANCL 2151
G CS+ + CSQ G C C P Y GD R+ C GCS+ C
Sbjct: 239 FSGPDCSQRSCPRGCSQRGRCEGGRCVCDPGYTGDDCGMRS---CP----RGCSQRGRC- 290
Query: 2152 STGLNTRRCECHAGYVGD 2169
RC C+ GY G+
Sbjct: 291 ----ENGRCVCNPGYTGE 304
Score = 58.2 bits (139), Expect = 1e-07
Identities = 42/143 (29%), Positives = 58/143 (40%), Gaps = 33/143 (23%)
Query: 85 SGCRRKCRKQVVQKACCPGYWGSRC--HECPGGAETPCNGHGTCLDGMDRNGTCVCQENF 142
S C + R + + C PGY G C CP C G G C+ G+ C+C +
Sbjct: 623 SNCHGRGRCEEGRCLCDPGYTGPTCATRMCPAD----CRGRGRCVQGV-----CLCHVGY 673
Query: 143 RGSACQECQDPNRFGPD-------CQS-VCSCVHG---------VCNHGPRG-----DGS 180
G C + + P P C++ C CV G C RG DGS
Sbjct: 674 GGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGDCRGRGECHDGS 733
Query: 181 CLCFAGYTGPHCDQELPVCQELR 203
C+C GY G C +E+P + +R
Sbjct: 734 CVCKDGYAGEDCGEEVPTIEGMR 756
Score = 48.9 bits (115), Expect = 6e-05
Identities = 46/153 (30%), Positives = 59/153 (38%), Gaps = 38/153 (24%)
Query: 1274 NCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKKIQVPD----CCPGFFGTLC 1329
NC R RC +G L D Y +R C C + + C G+ G C
Sbjct: 624 NCHGRGRCEEGRCLCDPG-----YTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDC 678
Query: 1330 ---EP----CPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCTGV 1382
EP CPGG C C+ +G+C C EGF G C + C G
Sbjct: 679 GQEEPPASACPGG----CGPRELCR-----AGQCVCVEGFRGPDCAI-------QTCPGD 722
Query: 1383 CDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKI 1415
C G C DGSCVC G+ G C +++
Sbjct: 723 CR-GRGECH-----DGSCVCKDGYAGEDCGEEV 749
Score = 34.7 bits (78), Expect = 1.2
Identities = 37/124 (29%), Positives = 47/124 (37%), Gaps = 35/124 (28%)
Query: 889 CTCHKGWSGDGRVCVAIDECEL------DMRGGCHTDALCSYVGP-GQSRCTCKLGFAGD 941
C+C GW G C + E+ G C D C+ G + RC C G+ G
Sbjct: 156 CSCEPGWGGP--TCSDPTDAEIPPSSPPSASGSCPDD--CNDQGRCVRGRCVCFPGYTGP 211
Query: 942 --GYQCSPIDPCRAGNGGC-HGLATCRAVGGG----QRV---------------CTCPPG 979
G+ P D C+ G G C G+ CRA G QR C C PG
Sbjct: 212 SCGWPSCPGD-CQ-GRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQRGRCEGGRCVCDPG 269
Query: 980 FGGD 983
+ GD
Sbjct: 270 YTGD 273
>gi|222352164 nel-like 1 isoform 1 precursor [Homo sapiens]
Length = 810
Score = 95.5 bits (236), Expect = 6e-19
Identities = 104/353 (29%), Positives = 141/353 (39%), Gaps = 79/353 (22%)
Query: 653 HCSEEQHKIVAGSC--VDCQALNTSTCPPNSVKLDIFPK-------ECVYIHDPTGLNVL 703
HC K A C + C LN C P+S+ + I + +C+Y G VL
Sbjct: 291 HCRNCTCKSGAVECRRMSCPPLN---CSPDSLPVHIAGQCCKVCRPKCIY-----GGKVL 342
Query: 704 KKGCASYCNQTIMEQGC--CKGFFGPDCTQ-CPGGFSNPCYGKGNCS--DGIQGNGACLC 758
+G Q I+ + C C+G T+ CP NCS D I C
Sbjct: 343 AEG------QRILTKSCRECRGGVLVKITEMCP---------PLNCSEKDHILPENQC-- 385
Query: 759 FPDYKGIACHICSNPN--KHGEQCQEDCGCVH----GLCDNRPGSGGVCQQGTCAPGFSG 812
C +C N G +C E+ C + C+ + SG + QG A
Sbjct: 386 --------CRVCRGHNFCAEGPKCGENSECKNWNTKATCECK--SGYISVQGDSA----- 430
Query: 813 RFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGF-EGDGFSCTPSNPCSHPDRG 871
+C E + +C +CH + CV+ G+ RC C+ G+ D FSCT + C
Sbjct: 431 -YC-EDIDECAAK--MHYCHANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHN 486
Query: 872 GCSENAECVPGSLGTHHCTCHKGWSGDGRVCVAIDECELDMRGGCHTDALCSYVGPGQSR 931
C ENA C G H CTC G+ G+G +C A CE GC C V P ++
Sbjct: 487 -CDENAICTNTVQG-HSCTCKPGYVGNGTICRAF--CE----EGCRYGGTC--VAP--NK 534
Query: 932 CTCKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGFGGDG 984
C C GF G + ID C G CH + C + G C C GF DG
Sbjct: 535 CVCPSGFTGSHCE-KDIDECSEGIIECHNHSRCVNLPGWYH-CECRSGFHDDG 585
Score = 75.5 bits (184), Expect = 6e-13
Identities = 89/342 (26%), Positives = 118/342 (34%), Gaps = 75/342 (21%)
Query: 1293 KSCVYRSGFSFSRGCSYTCAKKIQVPDCCPGFF-GTLCEPCPGGL--GGVCSGHGQCQDR 1349
++C +SG R S C PD P G C+ C GG GQ R
Sbjct: 293 RNCTCKSGAVECRRMS--CPPLNCSPDSLPVHIAGQCCKVCRPKCIYGGKVLAEGQ---R 347
Query: 1350 FLGSGECHCHEGFHGTACEVC------ELGRYGPN--CTGVCDCAHGLCQEGLQ-GDGS- 1399
L C G E+C E P C VC H C EG + G+ S
Sbjct: 348 ILTKSCRECRGGVLVKITEMCPPLNCSEKDHILPENQCCRVCR-GHNFCAEGPKCGENSE 406
Query: 1400 ---------CVCNVGWQGLRCDQKITSP--QCPRK---CDPNANCVQDSAGASTCACAAG 1445
C C G+ ++ D +C K C N CV + G C C G
Sbjct: 407 CKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCV-NLPGLYRCDCVPG 465
Query: 1446 YSGNGIF-CSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEI------ 1498
Y F C+E D C G C +A CT G +CTC+ GY+G+G +C+
Sbjct: 466 YIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGH-SCTCKPGYVGNGTICRAFCEEGCR 524
Query: 1499 --------NSCLIHHG------------------GCHIHAECIPTGPQQVSCSCREGYSG 1532
N C+ G CH H+ C+ P C CR G+
Sbjct: 525 YGGTCVAPNKCVCPSGFTGSHCEKDIDECSEGIIECHNHSRCVNL-PGWYHCECRSGFHD 583
Query: 1533 DGI-----RTCELLDPCSKNNGGCSPYATCKSTGDGQRTCTC 1569
DG +C +D C+ C + C + G C C
Sbjct: 584 DGTYSLSGESCIDIDECALRTHTCWNDSACINLAGG-FDCLC 624
Score = 73.6 bits (179), Expect = 2e-12
Identities = 86/339 (25%), Positives = 112/339 (33%), Gaps = 80/339 (23%)
Query: 1946 CHR-NCVTTTWKPSCCPGHYGSECQACPGGPSSPCSDRGVCMDGMSGSGQCL-------C 1997
C R +C P P H +C C + + + GQ + C
Sbjct: 304 CRRMSCPPLNCSPDSLPVHIAGQC-------CKVCRPKCIYGGKVLAEGQRILTKSCREC 356
Query: 1998 RSGFAGTACELCAP------GAFGPHCQACR-CTVHGRCDEGLGGSGSCFCDEGWTGPRC 2050
R G E+C P P Q CR C H C EG + C T C
Sbjct: 357 RGGVLVKITEMCPPLNCSEKDHILPENQCCRVCRGHNFCAEGPKCGENSECKNWNTKATC 416
Query: 2051 EVQLELQPV------CTP--PCAPEA-VCRAGN---------SCECSLGY-EGDGRVCTV 2091
E + V C CA + C A C+C GY D CT
Sbjct: 417 ECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDDFSCTE 476
Query: 2092 ADLCQDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWSCRA----------------RNP 2135
D C G C E+A C+ +CTC P Y G+G CRA +
Sbjct: 477 HDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGTICRAFCEEGCRYGGTCVAPNKCV 536
Query: 2136 CTDGHRGG---------------CSEHANCLSTGLNTRRCECHAGYVGDGLQCLE-ESEP 2179
C G G C H+ C++ CEC +G+ DG L ES
Sbjct: 537 CPSGFTGSHCEKDIDECSEGIIECHNHSRCVNLP-GWYHCECRSGFHDDGTYSLSGESCI 595
Query: 2180 PVDRCLGQPPPCHSDAMCTDLHFQEKRAGVFHLQATSGP 2218
+D C + C +D+ C +L AG F SGP
Sbjct: 596 DIDECALRTHTCWNDSACINL------AGGFDCLCPSGP 628
Score = 72.8 bits (177), Expect = 4e-12
Identities = 68/237 (28%), Positives = 90/237 (37%), Gaps = 36/237 (15%)
Query: 777 GEQCQEDCGCVHGLCDNRPGSGGVCQQGTCAPG-----FSGRFCNESMGDC--------- 822
G+ C+ +C C G + R S C C+P +G+ C C
Sbjct: 289 GDHCR-NCTCKSGAVECRRMS---CPPLNCSPDSLPVHIAGQCCKVCRPKCIYGGKVLAE 344
Query: 823 GPTGLAQHCHLHARCVSQEGVARCRCLDGFEGDGFSCTPSNPCSHPDRGG--------CS 874
G L + C V + C L+ E D P N C RG C
Sbjct: 345 GQRILTKSCRECRGGVLVKITEMCPPLNCSEKDHI--LPENQCCRVCRGHNFCAEGPKCG 402
Query: 875 ENAECVPGSLGTHHCTCHKGW---SGDGRVCVAIDECELDMRGGCHTDALCSYVGPGQSR 931
EN+EC + C C G+ GD C IDEC M CH + +C + PG R
Sbjct: 403 ENSECKNWNTKAT-CECKSGYISVQGDSAYCEDIDECAAKMHY-CHANTVCVNL-PGLYR 459
Query: 932 CTCKLGFAG-DGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGFGGDGFSC 987
C C G+ D + C+ D C +G C A C G CTC PG+ G+G C
Sbjct: 460 CDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHS-CTCKPGYVGNGTIC 515
Score = 64.7 bits (156), Expect = 1e-09
Identities = 55/196 (28%), Positives = 77/196 (39%), Gaps = 41/196 (20%)
Query: 720 CCKGFFGPD---CTQ---CPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNP 773
C G+ D CT+ C G N C C++ +QG+ +C C P Y G
Sbjct: 462 CVPGYIRVDDFSCTEHDECGSGQHN-CDENAICTNTVQGH-SCTCKPGYVG--------- 510
Query: 774 NKHGEQCQEDC--GCVHGLCDNRPGSGGVC---QQGTCAPGFSGRFCNESMGDCGPTGLA 828
+G C+ C GC +G G C + C GF+G C + + +C G+
Sbjct: 511 --NGTICRAFCEEGCRYG---------GTCVAPNKCVCPSGFTGSHCEKDIDECSE-GII 558
Query: 829 QHCHLHARCVSQEGVARCRCLDGFEGDGFSCTPSNPCSHPDRGG-----CSENAECVPGS 883
+ CH H+RCV+ G C C GF DG C D C ++ C+
Sbjct: 559 E-CHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACI-NL 616
Query: 884 LGTHHCTCHKGWSGDG 899
G C C G S G
Sbjct: 617 AGGFDCLCPSGPSCSG 632
Score = 61.6 bits (148), Expect = 1e-08
Identities = 53/196 (27%), Positives = 77/196 (39%), Gaps = 32/196 (16%)
Query: 1352 GSGECHCHEG------FHGTACEVCELGRYGPNCTGVCDCAHGLCQEGLQGDGSCVCNVG 1405
G C C G F T + C G++ CD + +C +QG SC C G
Sbjct: 456 GLYRCDCVPGYIRVDDFSCTEHDECGSGQHN------CD-ENAICTNTVQGH-SCTCKPG 507
Query: 1406 WQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTCACAAGYSGNGIFCS-EVDPCAHGHG 1464
+ G + I C C CV + C C +G++G+ C ++D C+ G
Sbjct: 508 YVG---NGTICRAFCEEGCRYGGTCV----APNKCVCPSGFTGS--HCEKDIDECSEGII 558
Query: 1465 GCSPHANCTKVAPGQRTCTCQDGYMGD------GELCQEINSCLIHHGGCHIHAECIPTG 1518
C H+ C + PG C C+ G+ D GE C +I+ C + C + CI
Sbjct: 559 ECHNHSRCVNL-PGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLA 617
Query: 1519 PQQVSCSCREGYSGDG 1534
C C G S G
Sbjct: 618 -GGFDCLCPSGPSCSG 632
Score = 60.5 bits (145), Expect = 2e-08
Identities = 46/163 (28%), Positives = 64/163 (39%), Gaps = 19/163 (11%)
Query: 198 VCQELRCPQNTQCSAEAPSCRCLPGYTQQGSECRAPNPCWPSP-CSLLAQCSVSPKGQAQ 256
+C L C + E CR CR N C P C ++C + +A
Sbjct: 367 MCPPLNCSEKDHILPENQCCRV----------CRGHNFCAEGPKCGENSECK-NWNTKAT 415
Query: 257 CHCPENY---HGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPGLVSINS-N 312
C C Y GD C D C + C +N T+CV PG C C PG + ++ +
Sbjct: 416 CECKSGYISVQGDSAYCEDIDECAAKMHYCHAN-TVCV-NLPGLYRCDCVPGYIRVDDFS 473
Query: 313 ASAGCFAFCSPFSCDRSATCQVTADGKTSCVCRESEVGDGRAC 355
+ +CD +A C T G SC C+ VG+G C
Sbjct: 474 CTEHDECGSGQHNCDENAICTNTVQGH-SCTCKPGYVGNGTIC 515
Score = 60.5 bits (145), Expect = 2e-08
Identities = 61/265 (23%), Positives = 101/265 (38%), Gaps = 64/265 (24%)
Query: 100 CCPGY-----WGSRCHECPGGAETPCNGHGTCLDGMDRNGTCVCQENF--RGSACQE-CQ 151
C PGY + H+ G + C+ + C + + + +C C+ + G+ C+ C+
Sbjct: 462 CVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGH-SCTCKPGYVGNGTICRAFCE 520
Query: 152 DPNRFGPDCQSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQELPVCQE--LRCPQNTQ 209
+ R+G C + C+C +G+TG HC++++ C E + C +++
Sbjct: 521 EGCRYGGTCVA---------------PNKCVCPSGFTGSHCEKDIDECSEGIIECHNHSR 565
Query: 210 CSAEAPS---CRCLPGYTQQGS------------ECR-APNPCW-PSPCSLLAQCSVSPK 252
C P C C G+ G+ EC + CW S C LA
Sbjct: 566 C-VNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLA------- 617
Query: 253 GQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPGLVSINSN 312
G C CP G C P + GG N + ++ + C+C+ G +
Sbjct: 618 GGFDCLCP-----SGPSCSGDCP---HEGGLKHNGQVWTLKEDRCSVCSCKDGKIFCRRT 669
Query: 313 A----SAGCFAFCSPFSCDRSATCQ 333
A + FC P CD T Q
Sbjct: 670 ACDCQNPSADLFCCP-ECDTRVTSQ 693
Score = 53.9 bits (128), Expect = 2e-06
Identities = 89/366 (24%), Positives = 120/366 (32%), Gaps = 90/366 (24%)
Query: 657 EQHKIVAGSCVDCQA----LNTSTCPPN--SVKLDIFPK-ECVYIHDPTGLNVLKKGCAS 709
E +I+ SC +C+ T CPP S K I P+ +C + G N +G
Sbjct: 344 EGQRILTKSCRECRGGVLVKITEMCPPLNCSEKDHILPENQCCRVC--RGHNFCAEG--P 399
Query: 710 YCNQTIMEQGCCKGFFGPDCTQCPGGFSNPCYGKGNCSD------------------GIQ 751
C E CK + +C G+ + C D +
Sbjct: 400 KCG----ENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLP 455
Query: 752 GNGACLCFPDYKGIACHICSNPNKHGE---QCQEDCGCVHGLCDNRPGSGGVCQQGTCAP 808
G C C P Y + C+ ++ G C E+ C + + G C TC P
Sbjct: 456 GLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTV------QGHSC---TCKP 506
Query: 809 GFSGR------FCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGDGFSCTPS 862
G+ G FC E C CV+ +C C GF G C
Sbjct: 507 GYVGNGTICRAFCEEG------------CRYGGTCVAPN---KCVCPSGFTGS--HCEKD 549
Query: 863 NPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGD------GRVCVAIDECELDMRGGC 916
C ++ CV G +HC C G+ D G C+ IDEC L C
Sbjct: 550 IDECSEGIIECHNHSRCV-NLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTH-TC 607
Query: 917 HTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAG---NGGCHGLATCRAVGGGQRV 973
D+ C + G C C G CS P G NG L R V
Sbjct: 608 WNDSACINLAGGFD-CLCP-----SGPSCSGDCPHEGGLKHNGQVWTLKEDRC-----SV 656
Query: 974 CTCPPG 979
C+C G
Sbjct: 657 CSCKDG 662
Score = 39.3 bits (90), Expect = 0.051
Identities = 57/206 (27%), Positives = 68/206 (33%), Gaps = 51/206 (24%)
Query: 1953 TTWKPSCCPGHYGSECQACPGGPSSPCSDRGVCMDGMSGSGQ-----------CLCRSG- 2000
T W S C G CP GPS CS G+ +GQ C C+ G
Sbjct: 606 TCWNDSACINLAGGFDCLCPSGPS--CSGDCPHEGGLKHNGQVWTLKEDRCSVCSCKDGK 663
Query: 2001 --FAGTACELCAPGAFGPHCQACRCTVHGRC------------DEGLGGSGSCFCDEG-- 2044
TAC+ P A C C V +C D C C EG
Sbjct: 664 IFCRRTACDCQNPSADLFCCPECDTRVTSQCLDQNGHKLYRSGDNWTHSCQQCRCLEGEV 723
Query: 2045 --W--TGPR--CEVQLELQPVCTPPCAPEAVCRAGN-------SCECSLGYEG-DGRVCT 2090
W T P CE L+ C P C + C A N +C S G G V T
Sbjct: 724 DCWPLTCPNLSCEYTAILEGECCPRCVSDP-CLADNITYDIRKTCLDSYGVSRLSGSVWT 782
Query: 2091 VAD------LCQDGHGGCSEHANCSQ 2110
+A C++G CS C Q
Sbjct: 783 MAGSPCTTCKCKNGRVCCSVDFECLQ 808
>gi|115298674 nidogen 1 precursor [Homo sapiens]
Length = 1247
Score = 95.1 bits (235), Expect = 8e-19
Identities = 68/208 (32%), Positives = 90/208 (43%), Gaps = 16/208 (7%)
Query: 1424 CDPNANCVQDSAGASTCACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCT 1483
CD NA C TC C+ G+ G+G C ++D C+ C H C PG C
Sbjct: 679 CDTNAACRPGPRTQFTCECSIGFRGDGRTCYDIDECSEQPSVCGSHTICNN-HPGTFRCE 737
Query: 1484 CQDGY-MGDGELC------QEINSCLIHHGGCHI--HAECIPTGPQQVSCSCREGYSGDG 1534
C +GY D C + IN C C I A+CI TG +CSC G+SGDG
Sbjct: 738 CVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLPGFSGDG 797
Query: 1535 IRTCELLDPCSKNNGGCSPYATCKSTGDGQRTCTCDTAHTVGDGLTCRARVGLELLRDKH 1594
+ C+ +D C + C P A C +T G TC C + GDG C +E R +H
Sbjct: 798 -QACQDVDECQPSR--CHPDAFCYNT-PGSFTCQCKPGYQ-GDGFRC-VPGEVEKTRCQH 851
Query: 1595 ASFFSLRLLEYKELKGDGPFTIFVPHAD 1622
L + + P +FVP D
Sbjct: 852 EREHILGAAGATDPQRPIPPGLFVPECD 879
Score = 89.0 bits (219), Expect = 6e-17
Identities = 66/231 (28%), Positives = 91/231 (39%), Gaps = 56/231 (24%)
Query: 726 GPDCTQCPGGFSNPCY-GKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQCQEDC 784
GP P NPCY G C N AC + G + Q C
Sbjct: 658 GPVREGSPDALQNPCYIGTHGCDT----NAAC------------------RPGPRTQFTC 695
Query: 785 GCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQEGVA 844
C G G G C + C+E CG H C + G
Sbjct: 696 ECSIGF----RGDGRTC--------YDIDECSEQPSVCGS---------HTICNNHPGTF 734
Query: 845 RCRCLDGF----EGDGFSCTPSNPCSHPDRG--GCS--ENAECVPGSLGTHHCTCHKGWS 896
RC C++G+ EG + P ++ + G C + A+C+ ++ C+C G+S
Sbjct: 735 RCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLPGFS 794
Query: 897 GDGRVCVAIDECELDMRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSP 947
GDG+ C +DEC+ CH DA C Y PG C CK G+ GDG++C P
Sbjct: 795 GDGQACQDVDECQPSR---CHPDAFC-YNTPGSFTCQCKPGYQGDGFRCVP 841
Score = 87.0 bits (214), Expect = 2e-16
Identities = 52/149 (34%), Positives = 66/149 (44%), Gaps = 19/149 (12%)
Query: 2061 TPPCAPEAVCRAGN----SCECSLGYEGDGRVCTVADLCQDGHGGCSEHANCSQVGTMVT 2116
T C A CR G +CECS+G+ GDGR C D C + C H C+
Sbjct: 676 THGCDTNAACRPGPRTQFTCECSIGFRGDGRTCYDIDECSEQPSVCGSHTICNNHPGTFR 735
Query: 2117 CTCLPDYE-GDGWSC------RARNPCTDG-HRGGCSEHANCLSTGLNTRRCECHAGYVG 2168
C C+ Y+ D +C R N C G H + A C+ TG ++ C C G+ G
Sbjct: 736 CECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLPGFSG 795
Query: 2169 DGLQCLEESEPPVDRCLGQPPPCHSDAMC 2197
DG C + VD C QP CH DA C
Sbjct: 796 DGQACQD-----VDEC--QPSRCHPDAFC 817
Score = 82.0 bits (201), Expect = 7e-15
Identities = 53/151 (35%), Positives = 65/151 (43%), Gaps = 15/151 (9%)
Query: 846 CRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWS-GDGRVCVA 904
C C GF GDG +C + CS C + C GT C C +G+ D CVA
Sbjct: 695 CECSIGFRGDGRTCYDIDECSEQP-SVCGSHTIC-NNHPGTFRCECVEGYQFSDEGTCVA 752
Query: 905 ------IDECELDMRGGCHTD--ALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNG 956
I+ CE + C A C Y G C+C GF+GDG C +D C+
Sbjct: 753 VVDQRPINYCETGLHN-CDIPQRAQCIYTGGSSYTCSCLPGFSGDGQACQDVDECQPSR- 810
Query: 957 GCHGLATCRAVGGGQRVCTCPPGFGGDGFSC 987
CH A C G C C PG+ GDGF C
Sbjct: 811 -CHPDAFCYNT-PGSFTCQCKPGYQGDGFRC 839
Score = 81.3 bits (199), Expect = 1e-14
Identities = 50/134 (37%), Positives = 60/134 (44%), Gaps = 12/134 (8%)
Query: 863 NPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGRVCVAIDECELDMRGGCHTDALC 922
NPC + GC NA C PG C C G+ GDGR C IDEC + C + +C
Sbjct: 670 NPC-YIGTHGCDTNAACRPGPRTQFTCECSIGFRGDGRTCYDIDECS-EQPSVCGSHTIC 727
Query: 923 SYVGPGQSRCTCKLGFA-GDGYQC------SPIDPCRAGNGGCH--GLATCRAVGGGQRV 973
+ PG RC C G+ D C PI+ C G C A C GG
Sbjct: 728 NN-HPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYT 786
Query: 974 CTCPPGFGGDGFSC 987
C+C PGF GDG +C
Sbjct: 787 CSCLPGFSGDGQAC 800
Score = 76.6 bits (187), Expect = 3e-13
Identities = 53/171 (30%), Positives = 69/171 (40%), Gaps = 26/171 (15%)
Query: 120 CNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHGVCNHGPRGDG 179
C+ + C G TC C FRG + C D + SVC H +CN+ P G
Sbjct: 679 CDTNAACRPGPRTQFTCECSIGFRGDG-RTCYDIDECSEQ-PSVCGS-HTICNNHP-GTF 734
Query: 180 SCLCFAGYTGP---------------HCDQELPVCQELRCPQNTQC---SAEAPSCRCLP 221
C C GY +C+ L C PQ QC + +C CLP
Sbjct: 735 RCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCD---IPQRAQCIYTGGSSYTCSCLP 791
Query: 222 GYTQQGSECRAPNPCWPSPCSLLAQCSVSPKGQAQCHCPENYHGDGMVCLP 272
G++ G C+ + C PS C A C +P G C C Y GDG C+P
Sbjct: 792 GFSGDGQACQDVDECQPSRCHPDAFCYNTP-GSFTCQCKPGYQGDGFRCVP 841
Score = 63.9 bits (154), Expect = 2e-09
Identities = 57/217 (26%), Positives = 75/217 (34%), Gaps = 40/217 (18%)
Query: 1979 CSDRGVCMDGMSGSGQCLCRSGFAGTA-----CELCA--PGAFGPH--CQACRCTVHGRC 2029
C C G C C GF G + C+ P G H C T C
Sbjct: 679 CDTNAACRPGPRTQFTCECSIGFRGDGRTCYDIDECSEQPSVCGSHTICNNHPGTFRCEC 738
Query: 2030 DEGLGGSGSCFCDEGWTGPRCEVQLELQPV---------CTPPCAPEAVCRAGNS--CEC 2078
EG F DEG C ++ +P+ C P + + G+S C C
Sbjct: 739 VEGYQ-----FSDEG----TCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSC 789
Query: 2079 SLGYEGDGRVCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWSC------RA 2132
G+ GDG+ C D CQ C A C TC C P Y+GDG+ C +
Sbjct: 790 LPGFSGDGQACQDVDECQPSR--CHPDAFCYNTPGSFTCQCKPGYQGDGFRCVPGEVEKT 847
Query: 2133 RNPCTDGH---RGGCSEHANCLSTGLNTRRCECHAGY 2166
R H G ++ + GL C+ H Y
Sbjct: 848 RCQHEREHILGAAGATDPQRPIPPGLFVPECDAHGHY 884
Score = 58.5 bits (140), Expect = 8e-08
Identities = 41/145 (28%), Positives = 56/145 (38%), Gaps = 13/145 (8%)
Query: 222 GYTQQGSECRAPNPCWPSP--CSLLAQCSVSPKGQAQCHCPENYHGDGMVCLPKDPCTDN 279
G ++GS NPC+ C A C P+ Q C C + GDG C D C++
Sbjct: 658 GPVREGSPDALQNPCYIGTHGCDTNAACRPGPRTQFTCECSIGFRGDGRTCYDIDECSEQ 717
Query: 280 LGGCPSNSTLCVYQKPGQAFCTCRPGLVSINSNASAGC-----FAFCSP--FSCD--RSA 330
C S+ T+C PG C C G + +C +CD + A
Sbjct: 718 PSVCGSH-TIC-NNHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRA 775
Query: 331 TCQVTADGKTSCVCRESEVGDGRAC 355
C T +C C GDG+AC
Sbjct: 776 QCIYTGGSSYTCSCLPGFSGDGQAC 800
Score = 57.4 bits (137), Expect = 2e-07
Identities = 50/202 (24%), Positives = 75/202 (37%), Gaps = 36/202 (17%)
Query: 729 CTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQCQEDCGCVH 788
C PG F C SD G C+ D + I + C H + C++
Sbjct: 727 CNNHPGTFRCECVEGYQFSD----EGTCVAVVDQRPI--NYCET-GLHNCDIPQRAQCIY 779
Query: 789 GLCDNRPGSGGVCQQGTCAPGFSG--RFCNESMGDCGPTGLAQHCHLHARCVSQEGVARC 846
+GG +C PGFSG + C + + +C P+ CH A C + G C
Sbjct: 780 --------TGGSSYTCSCLPGFSGDGQACQD-VDECQPS----RCHPDAFCYNTPGSFTC 826
Query: 847 RCLDGFEGDGFSCTP----SNPCSHP-----DRGGCSENAECVPGSLGTHHCTCHKGWS- 896
+C G++GDGF C P C H G ++ +P L C H ++
Sbjct: 827 QCKPGYQGDGFRCVPGEVEKTRCQHEREHILGAAGATDPQRPIPPGLFVPECDAHGHYAP 886
Query: 897 ----GDGRVCVAIDECELDMRG 914
G C +D ++ G
Sbjct: 887 TQCHGSTGYCWCVDRDGREVEG 908
Score = 52.0 bits (123), Expect = 8e-06
Identities = 43/152 (28%), Positives = 54/152 (35%), Gaps = 18/152 (11%)
Query: 216 SCRCLPGYTQQGSECRAPNPC--WPSPCSLLAQCSVSPKGQAQCHCPENYH-GDGMVCL- 271
+C C G+ G C + C PS C C+ P G +C C E Y D C+
Sbjct: 694 TCECSIGFRGDGRTCYDIDECSEQPSVCGSHTICNNHP-GTFRCECVEGYQFSDEGTCVA 752
Query: 272 -----PKDPCTDNLGGCP-SNSTLCVYQKPGQAFCTCRPGLVSINSNASAGCFAF--CSP 323
P + C L C C+Y C+C PG S C C P
Sbjct: 753 VVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLPGF----SGDGQACQDVDECQP 808
Query: 324 FSCDRSATCQVTADGKTSCVCRESEVGDGRAC 355
C A C T G +C C+ GDG C
Sbjct: 809 SRCHPDAFCYNTP-GSFTCQCKPGYQGDGFRC 839
Score = 50.8 bits (120), Expect = 2e-05
Identities = 52/209 (24%), Positives = 72/209 (34%), Gaps = 49/209 (23%)
Query: 2133 RNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGDGLQCLEESEPPVDRCLGQPPPCH 2192
+NPC G G C +A C CEC G+ GDG C + +D C QP C
Sbjct: 669 QNPCYIGTHG-CDTNAACRPGPRTQFTCECSIGFRGDGRTCYD-----IDECSEQPSVCG 722
Query: 2193 SDAMCTDLHFQEKRAGVFHLQATSGPYGLNFSEAEAACEA-----------QGAVLASFP 2241
S +C + G F + G FS+ E C A G P
Sbjct: 723 SHTICNN------HPGTFRCECVE---GYQFSD-EGTCVAVVDQRPINYCETGLHNCDIP 772
Query: 2242 QLSAAQQLGFH----LCLMGWLANGSTAHPVVFPVADCGNGRVGIVSLGARKNLSERWDA 2297
Q + G CL G+ +G V +C R DA
Sbjct: 773 QRAQCIYTGGSSYTCSCLPGFSGDGQACQ----DVDECQPSRC-------------HPDA 815
Query: 2298 YCFRVQ-DVACRCRNGFVGDGISTCNGKL 2325
+C+ C+C+ G+ GDG G++
Sbjct: 816 FCYNTPGSFTCQCKPGYQGDGFRCVPGEV 844
Score = 40.0 bits (92), Expect = 0.030
Identities = 18/40 (45%), Positives = 20/40 (50%)
Query: 949 DPCRAGNGGCHGLATCRAVGGGQRVCTCPPGFGGDGFSCY 988
+PC G GC A CR Q C C GF GDG +CY
Sbjct: 670 NPCYIGTHGCDTNAACRPGPRTQFTCECSIGFRGDGRTCY 709
Score = 38.1 bits (87), Expect = 0.11
Identities = 21/50 (42%), Positives = 27/50 (54%), Gaps = 6/50 (12%)
Query: 2132 ARNPCTDGHRGGCSEHANC--LSTGLNTRRCECHAGYVGDGLQCLEESEP 2179
+R C + +R CS HA C +TG C C AGY G+G QC+ E P
Sbjct: 386 SRQTCAN-NRHQCSVHAECRDYATGFC---CSCVAGYTGNGRQCVAEGSP 431
Score = 35.0 bits (79), Expect = 0.95
Identities = 14/38 (36%), Positives = 18/38 (47%)
Query: 2095 CQDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWSCRA 2132
C + CS HA C T C+C+ Y G+G C A
Sbjct: 390 CANNRHQCSVHAECRDYATGFCCSCVAGYTGNGRQCVA 427
Score = 35.0 bits (79), Expect = 0.95
Identities = 16/37 (43%), Positives = 19/37 (51%), Gaps = 1/37 (2%)
Query: 1459 CAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELC 1495
CA+ CS HA C A G C+C GY G+G C
Sbjct: 390 CANNRHQCSVHAECRDYATG-FCCSCVAGYTGNGRQC 425
Score = 33.5 bits (75), Expect = 2.8
Identities = 16/42 (38%), Positives = 22/42 (52%), Gaps = 1/42 (2%)
Query: 1412 DQKITSPQCPRKCDPNANCVQDSAGASTCACAAGYSGNGIFC 1453
D + T +C +A C +D A C+C AGY+GNG C
Sbjct: 385 DSRQTCANNRHQCSVHAEC-RDYATGFCCSCVAGYTGNGRQC 425
Score = 32.7 bits (73), Expect = 4.7
Identities = 18/45 (40%), Positives = 25/45 (55%), Gaps = 1/45 (2%)
Query: 860 TPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGRVCVA 904
T S +R CS +AEC + G C+C G++G+GR CVA
Sbjct: 384 TDSRQTCANNRHQCSVHAECRDYATG-FCCSCVAGYTGNGRQCVA 427
>gi|46249414 latent transforming growth factor beta binding protein 1
isoform LTBP-1L [Homo sapiens]
Length = 1722
Score = 94.7 bits (234), Expect = 1e-18
Identities = 95/351 (27%), Positives = 129/351 (36%), Gaps = 63/351 (17%)
Query: 652 KHCSEEQHKIVAGSCVDC-QALNTSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKGCASY 710
++C G C D + LN STCP +CV
Sbjct: 983 EYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCV------------------ 1024
Query: 711 CNQTIMEQGCCKGFFG--PDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACH 768
C +GF G C G+CS+ ++G+ C C Y H
Sbjct: 1025 --------PCTEGFRGWNGQCLDVDECLEPNVCANGDCSN-LEGSYMCSCHKGYTRTPDH 1075
Query: 769 ICSNPNKHG---EQCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPT 825
KH ++CQ+ CV+G C N GS + TC G+ + + C
Sbjct: 1076 ------KHCRDIDECQQGNLCVNGQCKNTEGS----FRCTCGQGYQ---LSAAKDQCEDI 1122
Query: 826 GLAQHCHL--HARCVSQEGVARCRCLDGFEGDGFS--CTPSNPCSHPDRGGCSENAECVP 881
QH HL H +C + EG +C C G+ G C N C D+ C + +C+
Sbjct: 1123 DECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLE-DKSVC-QRGDCI- 1179
Query: 882 GSLGTHHCTCHKGWS-GDGRVCVAIDECELDMRGGCHTDALCSYVGPGQSRCTCKLGF-- 938
+ G++ CTC G+ D + C I+ECE G C C G C C+ GF
Sbjct: 1180 NTAGSYDCTCPDGFQLDDNKTCQDINECE--HPGLCGPQGECLNT-EGSFHCVCQQGFSI 1236
Query: 939 AGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGFGG--DGFSC 987
+ DG C ID C N C C G R C C GF DG C
Sbjct: 1237 SADGRTCEDIDEC-VNNTVCDSHGFCDNTAGSFR-CLCYQGFQAPQDGQGC 1285
Score = 92.0 bits (227), Expect = 7e-18
Identities = 97/345 (28%), Positives = 135/345 (39%), Gaps = 44/345 (12%)
Query: 1269 REKCVN---CTR-RFRCTQGFQLQDTPRKSCVYRSGFSFSR-GCSYTCAKKIQVPDCCP- 1322
+ KCV+ CT+ + C+QG C+ +GF S G + + PD C
Sbjct: 911 QRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGE 970
Query: 1323 -------GFFGTLCEPCPGGLGGVCSGHGQCQDRFLGSGEC---HCHEGFHGTACEVCEL 1372
G F CE C G G + D L C C C C
Sbjct: 971 GHCVNTVGAFR--CEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTE 1028
Query: 1373 GRYGPN--CTGVCDCAH-GLCQEG----LQGDGSCVCNVGWQGLRCDQK----ITSPQCP 1421
G G N C V +C +C G L+G C C+ G+ D K I Q
Sbjct: 1029 GFRGWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTP-DHKHCRDIDECQQG 1087
Query: 1422 RKCDPNANCVQDSAGASTCACAAGY--SGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQ 1479
C N C +++ G+ C C GY S C ++D C H H H C G
Sbjct: 1088 NLC-VNGQC-KNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRH--LCAHGQCRNTE-GS 1142
Query: 1480 RTCTCQDGYM--GDGELCQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRT 1537
C C GY G G+ C++IN CL C +CI T C+C +G+ D +T
Sbjct: 1143 FQCVCDQGYRASGLGDHCEDINECLEDKSVCQ-RGDCINTAGSY-DCTCPDGFQLDDNKT 1200
Query: 1538 CELLDPCSKNNGGCSPYATCKSTGDGQRTCTCDTAHTV-GDGLTC 1581
C+ ++ C ++ G C P C +T +G C C ++ DG TC
Sbjct: 1201 CQDINEC-EHPGLCGPQGECLNT-EGSFHCVCQQGFSISADGRTC 1243
Score = 73.2 bits (178), Expect = 3e-12
Identities = 82/335 (24%), Positives = 122/335 (36%), Gaps = 50/335 (14%)
Query: 1281 CTQGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKKIQVPDC-----------CPGFFGTLC 1329
C G + R +C+ G+ FS K + + +C C G+
Sbjct: 885 CGAGHCINLPVRYTCICYEGYRFSE----QQRKCVDIDECTQVQHLCSQGRCENTEGSFL 940
Query: 1330 EPCPGGL-----GGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCTGVCD 1384
CP G G C +C + GE HC CE C+ G Y G C+
Sbjct: 941 CICPAGFMASEEGTNCIDVDECLRPDV-CGEGHCVNTVGAFRCEYCDSG-YRMTQRGRCE 998
Query: 1385 CAHGLCQEGLQGDGSCV----------CNVGWQGLRCDQKITSPQC--PRKCDPNANCVQ 1432
D CV C G++G Q + +C P C N +C
Sbjct: 999 DIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWN-GQCLDVDECLEPNVC-ANGDC-S 1055
Query: 1433 DSAGASTCACAAGYSG--NGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMG 1490
+ G+ C+C GY+ + C ++D C G+ + C K G CTC GY
Sbjct: 1056 NLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGN--LCVNGQC-KNTEGSFRCTCGQGYQL 1112
Query: 1491 DG--ELCQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRT-CELLDPCSKN 1547
+ C++I+ C H H +C T C C +GY G+ CE ++ C ++
Sbjct: 1113 SAAKDQCEDIDEC--QHRHLCAHGQCRNT-EGSFQCVCDQGYRASGLGDHCEDINECLED 1169
Query: 1548 NGGCSPYATCKSTGDGQRTCTCDTAHTVGDGLTCR 1582
C C +T G CTC + D TC+
Sbjct: 1170 KSVCQR-GDCINTA-GSYDCTCPDGFQLDDNKTCQ 1202
Score = 64.7 bits (156), Expect = 1e-09
Identities = 88/355 (24%), Positives = 119/355 (33%), Gaps = 63/355 (17%)
Query: 663 AGSCVDCQALNTSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKGCASYCNQTIMEQGCCK 722
AG C++ T C + ++CV I + T + Q + QG C+
Sbjct: 887 AGHCINLPVRYTCICY-EGYRFSEQQRKCVDIDECTQV------------QHLCSQGRCE 933
Query: 723 GFFGPDCTQCPGGFSNPCYGKGNCSD-------GIQGNGACLCFPDYKGIACHICSNPNK 775
G CP GF G NC D + G G C+ C C + +
Sbjct: 934 NTEGSFLCICPAGFMASEEGT-NCIDVDECLRPDVCGEGHCV--NTVGAFRCEYCDSGYR 990
Query: 776 HGE--------QCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTG- 826
+ +C C C N PGS Q C GF G G C
Sbjct: 991 MTQRGRCEDIDECLNPSTCPDEQCVNSPGS---YQCVPCTEGFRGW-----NGQCLDVDE 1042
Query: 827 -LAQHCHLHARCVSQEGVARCRCLDGFEG--DGFSCTPSNPCSHPDRGGCSENAECVPGS 883
L + + C + EG C C G+ D C + C +G N +C +
Sbjct: 1043 CLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQ---QGNLCVNGQC-KNT 1098
Query: 884 LGTHHCTCHKGW--SGDGRVCVAIDECE---LDMRGGCHTDALCSYVGPGQSRCTCKLGF 938
G+ CTC +G+ S C IDEC+ L G C G +C C G+
Sbjct: 1099 EGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTE-------GSFQCVCDQGY 1151
Query: 939 --AGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGFGGDGFSCYGDI 991
+G G C I+ C C G CTCP GF D DI
Sbjct: 1152 RASGLGDHCEDINECLEDKSVCQRGDCINTAGSYD--CTCPDGFQLDDNKTCQDI 1204
Score = 55.1 bits (131), Expect = 9e-07
Identities = 60/237 (25%), Positives = 82/237 (34%), Gaps = 53/237 (22%)
Query: 786 CVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQEGVAR 845
C G C N P V C G+ D QH RC + EG
Sbjct: 885 CGAGHCINLP----VRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFL 940
Query: 846 CRCLDGF--EGDGFSCTPSNPCSHPD---------------------------RGGCSEN 876
C C GF +G +C + C PD RG C +
Sbjct: 941 CICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDI 1000
Query: 877 AECV----------PGSLGTHHCT-CHKGWSGDGRVCVAIDECELDMRGGCHTDALCSYV 925
EC+ S G++ C C +G+ G C+ +DEC + + CS +
Sbjct: 1001 DECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDEC---LEPNVCANGDCSNL 1057
Query: 926 GPGQSRCTCKLGF--AGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGF 980
G C+C G+ D C ID C+ GN +G C+ G R CTC G+
Sbjct: 1058 -EGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNG--QCKNTEGSFR-CTCGQGY 1110
Score = 50.8 bits (120), Expect = 2e-05
Identities = 86/368 (23%), Positives = 132/368 (35%), Gaps = 93/368 (25%)
Query: 1258 SRCLHSHAEALREKCVNCTRRFRCT--QGFQLQDT----------------PRKSCVYRS 1299
+ CL + R C+N + CT GFQL D P+ C+
Sbjct: 1164 NECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTE 1223
Query: 1300 GFSFSRGCSYTCAKKIQVPDCCPGFF----GTLCEPCPGGLGG-VCSGHGQCQDRFLGSG 1354
G S+ C C GF G CE + VC HG C D GS
Sbjct: 1224 G-------SFHCV-------CQQGFSISADGRTCEDIDECVNNTVCDSHGFC-DNTAGSF 1268
Query: 1355 ECHCHEGFHGTACEVCELGRYGPNCTGV--CDCAHGLCQ----EGLQGDGSCVC---NVG 1405
C C++GF + + G C V C+ G+C E ++G CVC N
Sbjct: 1269 RCLCYQGF--------QAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQE 1320
Query: 1406 WQGL--RC--------DQKITSPQCPRK-----------CDPNANCVQDSAGASTCACAA 1444
+ + +C D + P+ +K CD N + + C C +
Sbjct: 1321 YSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCD---NVLAPNVTKQECCCTS 1377
Query: 1445 GYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQR--TCTCQDGYMGDGELCQEINSCL 1502
G +G G C E+ PC A T++ P + + GE ++ + CL
Sbjct: 1378 G-AGWGDNC-EIFPCP-----VLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECL 1430
Query: 1503 IHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIR-TCELLDPCSKNNGGCSPYATCKSTG 1561
+ + C+ T P C C++G D ++ C +D C ++ C C +T
Sbjct: 1431 LFGQEICKNGFCLNTRP-GYECYCKQGTYYDPVKLQCFDMDEC-QDPSSCID-GQCVNT- 1486
Query: 1562 DGQRTCTC 1569
+G C C
Sbjct: 1487 EGSYNCFC 1494
Score = 48.5 bits (114), Expect = 8e-05
Identities = 64/244 (26%), Positives = 91/244 (37%), Gaps = 44/244 (18%)
Query: 122 GHGTCLDGMDRNGTCVCQENFRGSACQ-ECQDPNRFGPDCQSVCSCVHGVCNHG----PR 176
G G C++ + TC+C E +R S Q +C D + C+ V +C+ G
Sbjct: 886 GAGHCIN-LPVRYTCICYEGYRFSEQQRKCVDIDE--------CTQVQHLCSQGRCENTE 936
Query: 177 GDGSCLCFAGYT----GPHC---DQEL--PVCQELRCPQNTQCSAEAPSCRCLPGYTQQG 227
G C+C AG+ G +C D+ L VC E C NT + C TQ+G
Sbjct: 937 GSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCV-NTVGAFRCEYCDSGYRMTQRG 995
Query: 228 -----SECRAPNPCWPSPCSLLAQCSVSPKGQAQC-HCPENYHGDGMVCLPKDPCTD-NL 280
EC P+ C C V+ G QC C E + G CL D C + N+
Sbjct: 996 RCEDIDECLNPSTCPDEQC-------VNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNV 1048
Query: 281 GGCPSNSTLCVYQKPGQAFCTCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVTADGKT 340
S L G C+C G + C + + C+ T +G
Sbjct: 1049 CANGDCSNL-----EGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNT-EGSF 1102
Query: 341 SCVC 344
C C
Sbjct: 1103 RCTC 1106
Score = 41.2 bits (95), Expect = 0.013
Identities = 41/165 (24%), Positives = 57/165 (34%), Gaps = 26/165 (15%)
Query: 758 CFPDYKGIACHICSNPNKHGEQCQEDCGCVHGL-----CDNRPGSGGVCQQGTCAPGF-- 810
CF + G C E C G G C +P G Q C PG+
Sbjct: 559 CFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKR 618
Query: 811 -SGRFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGDG--FSCTPSNPCSH 867
+ FC + + +C G+ + C++ G RC C GF D SC P P
Sbjct: 619 VNNTFCQD-INECQLQGVCPN----GECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVIS 673
Query: 868 PDRGGC----SENAECVPGSLGTH------HCTCHKGWSGDGRVC 902
++G C S +C+ L H C+ K W C
Sbjct: 674 EEKGPCYRLVSSGRQCM-HPLSVHLTKQLCCCSVGKAWGPHCEKC 717
Score = 40.8 bits (94), Expect = 0.017
Identities = 45/173 (26%), Positives = 62/173 (35%), Gaps = 45/173 (26%)
Query: 93 KQVVQKACCPGYWGSRCHECPGG--------------AETP--CNGHGTCLDGMDRNGTC 136
K V Q+ C GS CP G E P C G CL+ + + C
Sbjct: 1170 KSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLN-TEGSFHC 1228
Query: 137 VCQENFRGSACQECQDPNRFGPDCQSVCSCV-------HGVCNHGPRGDGSCLCFAGYTG 189
VCQ+ F SA G C+ + CV HG C++ G CLC+ G+
Sbjct: 1229 VCQQGFSISAD---------GRTCEDIDECVNNTVCDSHGFCDN-TAGSFRCLCYQGFQA 1278
Query: 190 P----------HCDQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQGSECRA 232
P C+ VC E C +N + S Y+ +CR+
Sbjct: 1279 PQDGQGCVDVNECELLSGVCGEAFC-ENVEGSFLCVCADENQEYSPMTGQCRS 1330
Score = 39.3 bits (90), Expect = 0.051
Identities = 59/266 (22%), Positives = 82/266 (30%), Gaps = 48/266 (18%)
Query: 1938 RPQGLGRGCHRNCVTTTWKPSCCPGHYGSECQACPGGPSSPCSDRGVCMD----GMSGSG 1993
RP G G N V C G+ ++ C C + C D GS
Sbjct: 964 RPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCED--IDECLNPSTCPDEQCVNSPGSY 1021
Query: 1994 QCL-CRSGFAGTACELCAPGAFGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEV 2052
QC+ C GF G + C +G C L GS C C +G+T
Sbjct: 1022 QCVPCTEGFRGWNGQCLDVD----ECLEPNVCANGDCSN-LEGSYMCSCHKGYTR----- 1071
Query: 2053 QLELQPVCTPP---CAPEAVCRAGN--------------SCECSLGYEGDGRVCTVADLC 2095
TP C C+ GN C C GY+ D+
Sbjct: 1072 --------TPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDID 1123
Query: 2096 QDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWS--CRARNPCTDGHRGGCSEHANCLST 2153
+ H H C C C Y G C N C + + +C++T
Sbjct: 1124 ECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDK--SVCQRGDCINT 1181
Query: 2154 GLNTRRCECHAGY-VGDGLQCLEESE 2178
+ C C G+ + D C + +E
Sbjct: 1182 A-GSYDCTCPDGFQLDDNKTCQDINE 1206
Score = 39.3 bits (90), Expect = 0.051
Identities = 50/207 (24%), Positives = 70/207 (33%), Gaps = 67/207 (32%)
Query: 1946 CHR-NCVTTTWKPSC-CPGHYG----------SECQACPGGPSSPCSDRGVCMDGMSGSG 1993
C R +C+ T C CP + +EC+ PG C +G C++ GS
Sbjct: 1173 CQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEH-PG----LCGPQGECLN-TEGSF 1226
Query: 1994 QCLCRSGFAGTACELCAPGAFGPHCQAC----RCTVHGRCDEGLGGSGSCFCDEGWTGPR 2049
C+C+ GF+ + A G C C HG CD GS C C +G+ P+
Sbjct: 1227 HCVCQQGFS-----ISADGRTCEDIDECVNNTVCDSHGFCD-NTAGSFRCLCYQGFQAPQ 1280
Query: 2050 CEVQLELQPVCTPPCAPEAVCRAGNSCECSLGYEGDGRVCTVADLCQDGHGGCSEHANCS 2109
DG+ C + C+ G C E A C
Sbjct: 1281 -----------------------------------DGQGCVDVNECELLSGVCGE-AFCE 1304
Query: 2110 QVGTMVTCTCL---PDYEGDGWSCRAR 2133
V C C +Y CR+R
Sbjct: 1305 NVEGSFLCVCADENQEYSPMTGQCRSR 1331
Score = 34.3 bits (77), Expect = 1.6
Identities = 30/106 (28%), Positives = 43/106 (40%), Gaps = 22/106 (20%)
Query: 861 PSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGRVCVAIDECELDMRGGCHTDA 920
P P H G ++ EC+PG ++ C I+EC+L +G C
Sbjct: 598 PKKPSYH----GYNQMMECLPGYKRVNNTFCQD-----------INECQL--QGVCPNGE 640
Query: 921 LCSYVGPGQSRCTCKLGFAGDG--YQCSPIDP-CRAGNGGCHGLAT 963
+ +G RCTCK+GF D C P P G C+ L +
Sbjct: 641 CLNTMG--SYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVS 684
Score = 32.3 bits (72), Expect = 6.2
Identities = 25/99 (25%), Positives = 41/99 (41%), Gaps = 13/99 (13%)
Query: 774 NKHGEQCQEDCGCVHGLCDN----RPGSGGVCQQGTCAPGF---SGRFCNESMGDCGPTG 826
N E E+CG ++G C+N R G C C G+ + + + +C
Sbjct: 1616 NSFEELQAEECGILNG-CENGRCVRVQEGYTCD---CFDGYHLDTAKMTCVDVNECDELN 1671
Query: 827 LAQHCHLHARCVSQEGVARCRCLDGF--EGDGFSCTPSN 863
+A+C++ +G +C CL G+ CTP N
Sbjct: 1672 NRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLN 1710
>gi|46249412 latent transforming growth factor beta binding protein
1 isoform LTBP-1S [Homo sapiens]
Length = 1396
Score = 94.7 bits (234), Expect = 1e-18
Identities = 95/351 (27%), Positives = 129/351 (36%), Gaps = 63/351 (17%)
Query: 652 KHCSEEQHKIVAGSCVDC-QALNTSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKGCASY 710
++C G C D + LN STCP +CV
Sbjct: 657 EYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCV------------------ 698
Query: 711 CNQTIMEQGCCKGFFG--PDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACH 768
C +GF G C G+CS+ ++G+ C C Y H
Sbjct: 699 --------PCTEGFRGWNGQCLDVDECLEPNVCANGDCSN-LEGSYMCSCHKGYTRTPDH 749
Query: 769 ICSNPNKHG---EQCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPT 825
KH ++CQ+ CV+G C N GS + TC G+ + + C
Sbjct: 750 ------KHCRDIDECQQGNLCVNGQCKNTEGS----FRCTCGQGYQ---LSAAKDQCEDI 796
Query: 826 GLAQHCHL--HARCVSQEGVARCRCLDGFEGDGFS--CTPSNPCSHPDRGGCSENAECVP 881
QH HL H +C + EG +C C G+ G C N C D+ C + +C+
Sbjct: 797 DECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLE-DKSVC-QRGDCI- 853
Query: 882 GSLGTHHCTCHKGWS-GDGRVCVAIDECELDMRGGCHTDALCSYVGPGQSRCTCKLGF-- 938
+ G++ CTC G+ D + C I+ECE G C C G C C+ GF
Sbjct: 854 NTAGSYDCTCPDGFQLDDNKTCQDINECE--HPGLCGPQGECLNT-EGSFHCVCQQGFSI 910
Query: 939 AGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGFGG--DGFSC 987
+ DG C ID C N C C G R C C GF DG C
Sbjct: 911 SADGRTCEDIDEC-VNNTVCDSHGFCDNTAGSFR-CLCYQGFQAPQDGQGC 959
Score = 92.0 bits (227), Expect = 7e-18
Identities = 97/345 (28%), Positives = 135/345 (39%), Gaps = 44/345 (12%)
Query: 1269 REKCVN---CTR-RFRCTQGFQLQDTPRKSCVYRSGFSFSR-GCSYTCAKKIQVPDCCP- 1322
+ KCV+ CT+ + C+QG C+ +GF S G + + PD C
Sbjct: 585 QRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGE 644
Query: 1323 -------GFFGTLCEPCPGGLGGVCSGHGQCQDRFLGSGEC---HCHEGFHGTACEVCEL 1372
G F CE C G G + D L C C C C
Sbjct: 645 GHCVNTVGAFR--CEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTE 702
Query: 1373 GRYGPN--CTGVCDCAH-GLCQEG----LQGDGSCVCNVGWQGLRCDQK----ITSPQCP 1421
G G N C V +C +C G L+G C C+ G+ D K I Q
Sbjct: 703 GFRGWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTP-DHKHCRDIDECQQG 761
Query: 1422 RKCDPNANCVQDSAGASTCACAAGY--SGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQ 1479
C N C +++ G+ C C GY S C ++D C H H H C G
Sbjct: 762 NLC-VNGQC-KNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRH--LCAHGQCRNTE-GS 816
Query: 1480 RTCTCQDGYM--GDGELCQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRT 1537
C C GY G G+ C++IN CL C +CI T C+C +G+ D +T
Sbjct: 817 FQCVCDQGYRASGLGDHCEDINECLEDKSVCQ-RGDCINTAGSY-DCTCPDGFQLDDNKT 874
Query: 1538 CELLDPCSKNNGGCSPYATCKSTGDGQRTCTCDTAHTV-GDGLTC 1581
C+ ++ C ++ G C P C +T +G C C ++ DG TC
Sbjct: 875 CQDINEC-EHPGLCGPQGECLNT-EGSFHCVCQQGFSISADGRTC 917
Score = 73.2 bits (178), Expect = 3e-12
Identities = 82/335 (24%), Positives = 122/335 (36%), Gaps = 50/335 (14%)
Query: 1281 CTQGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKKIQVPDC-----------CPGFFGTLC 1329
C G + R +C+ G+ FS K + + +C C G+
Sbjct: 559 CGAGHCINLPVRYTCICYEGYRFSE----QQRKCVDIDECTQVQHLCSQGRCENTEGSFL 614
Query: 1330 EPCPGGL-----GGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCTGVCD 1384
CP G G C +C + GE HC CE C+ G Y G C+
Sbjct: 615 CICPAGFMASEEGTNCIDVDECLRPDV-CGEGHCVNTVGAFRCEYCDSG-YRMTQRGRCE 672
Query: 1385 CAHGLCQEGLQGDGSCV----------CNVGWQGLRCDQKITSPQC--PRKCDPNANCVQ 1432
D CV C G++G Q + +C P C N +C
Sbjct: 673 DIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWN-GQCLDVDECLEPNVC-ANGDC-S 729
Query: 1433 DSAGASTCACAAGYSG--NGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMG 1490
+ G+ C+C GY+ + C ++D C G+ + C K G CTC GY
Sbjct: 730 NLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGN--LCVNGQC-KNTEGSFRCTCGQGYQL 786
Query: 1491 DG--ELCQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRT-CELLDPCSKN 1547
+ C++I+ C H H +C T C C +GY G+ CE ++ C ++
Sbjct: 787 SAAKDQCEDIDEC--QHRHLCAHGQCRNT-EGSFQCVCDQGYRASGLGDHCEDINECLED 843
Query: 1548 NGGCSPYATCKSTGDGQRTCTCDTAHTVGDGLTCR 1582
C C +T G CTC + D TC+
Sbjct: 844 KSVCQR-GDCINTA-GSYDCTCPDGFQLDDNKTCQ 876
Score = 64.7 bits (156), Expect = 1e-09
Identities = 88/355 (24%), Positives = 119/355 (33%), Gaps = 63/355 (17%)
Query: 663 AGSCVDCQALNTSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKGCASYCNQTIMEQGCCK 722
AG C++ T C + ++CV I + T + Q + QG C+
Sbjct: 561 AGHCINLPVRYTCICY-EGYRFSEQQRKCVDIDECTQV------------QHLCSQGRCE 607
Query: 723 GFFGPDCTQCPGGFSNPCYGKGNCSD-------GIQGNGACLCFPDYKGIACHICSNPNK 775
G CP GF G NC D + G G C+ C C + +
Sbjct: 608 NTEGSFLCICPAGFMASEEGT-NCIDVDECLRPDVCGEGHCV--NTVGAFRCEYCDSGYR 664
Query: 776 HGE--------QCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTG- 826
+ +C C C N PGS Q C GF G G C
Sbjct: 665 MTQRGRCEDIDECLNPSTCPDEQCVNSPGS---YQCVPCTEGFRGW-----NGQCLDVDE 716
Query: 827 -LAQHCHLHARCVSQEGVARCRCLDGFEG--DGFSCTPSNPCSHPDRGGCSENAECVPGS 883
L + + C + EG C C G+ D C + C +G N +C +
Sbjct: 717 CLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQ---QGNLCVNGQC-KNT 772
Query: 884 LGTHHCTCHKGW--SGDGRVCVAIDECE---LDMRGGCHTDALCSYVGPGQSRCTCKLGF 938
G+ CTC +G+ S C IDEC+ L G C G +C C G+
Sbjct: 773 EGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTE-------GSFQCVCDQGY 825
Query: 939 --AGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGFGGDGFSCYGDI 991
+G G C I+ C C G CTCP GF D DI
Sbjct: 826 RASGLGDHCEDINECLEDKSVCQRGDCINTAGSYD--CTCPDGFQLDDNKTCQDI 878
Score = 55.1 bits (131), Expect = 9e-07
Identities = 60/237 (25%), Positives = 82/237 (34%), Gaps = 53/237 (22%)
Query: 786 CVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQEGVAR 845
C G C N P V C G+ D QH RC + EG
Sbjct: 559 CGAGHCINLP----VRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFL 614
Query: 846 CRCLDGF--EGDGFSCTPSNPCSHPD---------------------------RGGCSEN 876
C C GF +G +C + C PD RG C +
Sbjct: 615 CICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDI 674
Query: 877 AECV----------PGSLGTHHCT-CHKGWSGDGRVCVAIDECELDMRGGCHTDALCSYV 925
EC+ S G++ C C +G+ G C+ +DEC + + CS +
Sbjct: 675 DECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDEC---LEPNVCANGDCSNL 731
Query: 926 GPGQSRCTCKLGF--AGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGF 980
G C+C G+ D C ID C+ GN +G C+ G R CTC G+
Sbjct: 732 -EGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNG--QCKNTEGSFR-CTCGQGY 784
Score = 50.8 bits (120), Expect = 2e-05
Identities = 86/368 (23%), Positives = 132/368 (35%), Gaps = 93/368 (25%)
Query: 1258 SRCLHSHAEALREKCVNCTRRFRCT--QGFQLQDT----------------PRKSCVYRS 1299
+ CL + R C+N + CT GFQL D P+ C+
Sbjct: 838 NECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTE 897
Query: 1300 GFSFSRGCSYTCAKKIQVPDCCPGFF----GTLCEPCPGGLGG-VCSGHGQCQDRFLGSG 1354
G S+ C C GF G CE + VC HG C D GS
Sbjct: 898 G-------SFHCV-------CQQGFSISADGRTCEDIDECVNNTVCDSHGFC-DNTAGSF 942
Query: 1355 ECHCHEGFHGTACEVCELGRYGPNCTGV--CDCAHGLCQ----EGLQGDGSCVC---NVG 1405
C C++GF + + G C V C+ G+C E ++G CVC N
Sbjct: 943 RCLCYQGF--------QAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQE 994
Query: 1406 WQGL--RC--------DQKITSPQCPRK-----------CDPNANCVQDSAGASTCACAA 1444
+ + +C D + P+ +K CD N + + C C +
Sbjct: 995 YSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCD---NVLAPNVTKQECCCTS 1051
Query: 1445 GYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQR--TCTCQDGYMGDGELCQEINSCL 1502
G +G G C E+ PC A T++ P + + GE ++ + CL
Sbjct: 1052 G-AGWGDNC-EIFPCP-----VLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECL 1104
Query: 1503 IHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIR-TCELLDPCSKNNGGCSPYATCKSTG 1561
+ + C+ T P C C++G D ++ C +D C ++ C C +T
Sbjct: 1105 LFGQEICKNGFCLNTRP-GYECYCKQGTYYDPVKLQCFDMDEC-QDPSSCID-GQCVNT- 1160
Query: 1562 DGQRTCTC 1569
+G C C
Sbjct: 1161 EGSYNCFC 1168
Score = 48.5 bits (114), Expect = 8e-05
Identities = 64/244 (26%), Positives = 91/244 (37%), Gaps = 44/244 (18%)
Query: 122 GHGTCLDGMDRNGTCVCQENFRGSACQ-ECQDPNRFGPDCQSVCSCVHGVCNHG----PR 176
G G C++ + TC+C E +R S Q +C D + C+ V +C+ G
Sbjct: 560 GAGHCIN-LPVRYTCICYEGYRFSEQQRKCVDIDE--------CTQVQHLCSQGRCENTE 610
Query: 177 GDGSCLCFAGYT----GPHC---DQEL--PVCQELRCPQNTQCSAEAPSCRCLPGYTQQG 227
G C+C AG+ G +C D+ L VC E C NT + C TQ+G
Sbjct: 611 GSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCV-NTVGAFRCEYCDSGYRMTQRG 669
Query: 228 -----SECRAPNPCWPSPCSLLAQCSVSPKGQAQC-HCPENYHGDGMVCLPKDPCTD-NL 280
EC P+ C C V+ G QC C E + G CL D C + N+
Sbjct: 670 RCEDIDECLNPSTCPDEQC-------VNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNV 722
Query: 281 GGCPSNSTLCVYQKPGQAFCTCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVTADGKT 340
S L G C+C G + C + + C+ T +G
Sbjct: 723 CANGDCSNL-----EGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNT-EGSF 776
Query: 341 SCVC 344
C C
Sbjct: 777 RCTC 780
Score = 41.2 bits (95), Expect = 0.013
Identities = 41/165 (24%), Positives = 57/165 (34%), Gaps = 26/165 (15%)
Query: 758 CFPDYKGIACHICSNPNKHGEQCQEDCGCVHGL-----CDNRPGSGGVCQQGTCAPGF-- 810
CF + G C E C G G C +P G Q C PG+
Sbjct: 233 CFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKR 292
Query: 811 -SGRFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGDG--FSCTPSNPCSH 867
+ FC + + +C G+ + C++ G RC C GF D SC P P
Sbjct: 293 VNNTFCQD-INECQLQGVCPN----GECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVIS 347
Query: 868 PDRGGC----SENAECVPGSLGTH------HCTCHKGWSGDGRVC 902
++G C S +C+ L H C+ K W C
Sbjct: 348 EEKGPCYRLVSSGRQCM-HPLSVHLTKQLCCCSVGKAWGPHCEKC 391
Score = 40.8 bits (94), Expect = 0.017
Identities = 45/173 (26%), Positives = 62/173 (35%), Gaps = 45/173 (26%)
Query: 93 KQVVQKACCPGYWGSRCHECPGG--------------AETP--CNGHGTCLDGMDRNGTC 136
K V Q+ C GS CP G E P C G CL+ + + C
Sbjct: 844 KSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLN-TEGSFHC 902
Query: 137 VCQENFRGSACQECQDPNRFGPDCQSVCSCV-------HGVCNHGPRGDGSCLCFAGYTG 189
VCQ+ F SA G C+ + CV HG C++ G CLC+ G+
Sbjct: 903 VCQQGFSISAD---------GRTCEDIDECVNNTVCDSHGFCDN-TAGSFRCLCYQGFQA 952
Query: 190 P----------HCDQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQGSECRA 232
P C+ VC E C +N + S Y+ +CR+
Sbjct: 953 PQDGQGCVDVNECELLSGVCGEAFC-ENVEGSFLCVCADENQEYSPMTGQCRS 1004
Score = 39.3 bits (90), Expect = 0.051
Identities = 59/266 (22%), Positives = 82/266 (30%), Gaps = 48/266 (18%)
Query: 1938 RPQGLGRGCHRNCVTTTWKPSCCPGHYGSECQACPGGPSSPCSDRGVCMD----GMSGSG 1993
RP G G N V C G+ ++ C C + C D GS
Sbjct: 638 RPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCED--IDECLNPSTCPDEQCVNSPGSY 695
Query: 1994 QCL-CRSGFAGTACELCAPGAFGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEV 2052
QC+ C GF G + C +G C L GS C C +G+T
Sbjct: 696 QCVPCTEGFRGWNGQCLDVD----ECLEPNVCANGDCSN-LEGSYMCSCHKGYTR----- 745
Query: 2053 QLELQPVCTPP---CAPEAVCRAGN--------------SCECSLGYEGDGRVCTVADLC 2095
TP C C+ GN C C GY+ D+
Sbjct: 746 --------TPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDID 797
Query: 2096 QDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWS--CRARNPCTDGHRGGCSEHANCLST 2153
+ H H C C C Y G C N C + + +C++T
Sbjct: 798 ECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDK--SVCQRGDCINT 855
Query: 2154 GLNTRRCECHAGY-VGDGLQCLEESE 2178
+ C C G+ + D C + +E
Sbjct: 856 A-GSYDCTCPDGFQLDDNKTCQDINE 880
Score = 39.3 bits (90), Expect = 0.051
Identities = 50/207 (24%), Positives = 70/207 (33%), Gaps = 67/207 (32%)
Query: 1946 CHR-NCVTTTWKPSC-CPGHYG----------SECQACPGGPSSPCSDRGVCMDGMSGSG 1993
C R +C+ T C CP + +EC+ PG C +G C++ GS
Sbjct: 847 CQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEH-PG----LCGPQGECLN-TEGSF 900
Query: 1994 QCLCRSGFAGTACELCAPGAFGPHCQAC----RCTVHGRCDEGLGGSGSCFCDEGWTGPR 2049
C+C+ GF+ + A G C C HG CD GS C C +G+ P+
Sbjct: 901 HCVCQQGFS-----ISADGRTCEDIDECVNNTVCDSHGFCD-NTAGSFRCLCYQGFQAPQ 954
Query: 2050 CEVQLELQPVCTPPCAPEAVCRAGNSCECSLGYEGDGRVCTVADLCQDGHGGCSEHANCS 2109
DG+ C + C+ G C E A C
Sbjct: 955 -----------------------------------DGQGCVDVNECELLSGVCGE-AFCE 978
Query: 2110 QVGTMVTCTCL---PDYEGDGWSCRAR 2133
V C C +Y CR+R
Sbjct: 979 NVEGSFLCVCADENQEYSPMTGQCRSR 1005
Score = 34.3 bits (77), Expect = 1.6
Identities = 30/106 (28%), Positives = 43/106 (40%), Gaps = 22/106 (20%)
Query: 861 PSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGRVCVAIDECELDMRGGCHTDA 920
P P H G ++ EC+PG ++ C I+EC+L +G C
Sbjct: 272 PKKPSYH----GYNQMMECLPGYKRVNNTFCQD-----------INECQL--QGVCPNGE 314
Query: 921 LCSYVGPGQSRCTCKLGFAGDG--YQCSPIDP-CRAGNGGCHGLAT 963
+ +G RCTCK+GF D C P P G C+ L +
Sbjct: 315 CLNTMG--SYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVS 358
Score = 32.3 bits (72), Expect = 6.2
Identities = 25/99 (25%), Positives = 41/99 (41%), Gaps = 13/99 (13%)
Query: 774 NKHGEQCQEDCGCVHGLCDN----RPGSGGVCQQGTCAPGF---SGRFCNESMGDCGPTG 826
N E E+CG ++G C+N R G C C G+ + + + +C
Sbjct: 1290 NSFEELQAEECGILNG-CENGRCVRVQEGYTCD---CFDGYHLDTAKMTCVDVNECDELN 1345
Query: 827 LAQHCHLHARCVSQEGVARCRCLDGF--EGDGFSCTPSN 863
+A+C++ +G +C CL G+ CTP N
Sbjct: 1346 NRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLN 1384
>gi|9506545 delta-like 4 protein precursor [Homo sapiens]
Length = 685
Score = 94.7 bits (234), Expect = 1e-18
Identities = 87/297 (29%), Positives = 112/297 (37%), Gaps = 40/297 (13%)
Query: 56 PSGWLRELPDQITQDCRYEVQLGGSMVSMSGCRRKCRKQVVQKACCPGYWGSRCHECPGG 115
P G L LP + C+ + L G C + + C PG+ G C+EC
Sbjct: 202 PDGNLSCLPGWTGEYCQQPICLSGCHEQNGYCSKPA-----ECLCRPGWQGRLCNEC--- 253
Query: 116 AETPCNG--HGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHGV-CN 172
P NG HGTC C C E + G C QD N C C +G C+
Sbjct: 254 --IPHNGCRHGTCSTPWQ----CTCDEGWGGLFCD--QDLNY----CTHHSPCKNGATCS 301
Query: 173 HGPRGDGSCLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAPS--CRCLPGYTQQGSEC 230
+ + +C C GYTG C+ EL C C C + C C PGY G C
Sbjct: 302 NSGQRSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPPGY--YGLHC 359
Query: 231 -RAPNPCWPSPCSLLAQCSVSPKG-QAQCHCPENYHGDGMVCLPK-DPCTDNLGGCPSNS 287
+ C SPC C +G C CP N+ G C K D CT N C +N
Sbjct: 360 EHSTLSCADSPCFNGGSCRERNQGANYACECPPNFTGSN--CEKKVDRCTSN--PC-ANG 414
Query: 288 TLCVYQKPGQAFCTCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVTADGKTSCVC 344
C+ + P + C CRPG + C+ C TC +G C C
Sbjct: 415 GQCLNRGPSR-MCRCRPGFTGTYCELHV---SDCARNPCAHGGTCHDLENG-LMCTC 466
Score = 91.7 bits (226), Expect = 9e-18
Identities = 114/434 (26%), Positives = 156/434 (35%), Gaps = 98/434 (22%)
Query: 1205 GGHRNSLLGPAHWIVFYNHSGQPEVNHVPLEGPMLEA-PGRSLIG---LSGVLTVGSSRC 1260
GG RN L P ++ S E H P + EA P +LI + G L VG +
Sbjct: 97 GGGRNPLQLPFNFTWPGTFSLIIEAWHAPGDDLRPEALPPDALISKIAIQGSLAVGQNWL 156
Query: 1261 LHSHAEALREKCVNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKK------ 1314
L L + + R C+ + + CS C K+
Sbjct: 157 LDEQTSTLTR--LRYSYRVICSDNY-----------------YGDNCSRLCKKRNDHFGH 197
Query: 1315 -IQVPD----CCPGFFGTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEV 1369
+ PD C PG+ G C+ P L G +G C EC C G+ G C
Sbjct: 198 YVCQPDGNLSCLPGWTGEYCQQ-PICLSGCHEQNGYCSK----PAECLCRPGWQGRLCNE 252
Query: 1370 CELGRYGPNCTGVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNAN 1429
C + G C HG C Q C C+ GW GL CDQ + C A
Sbjct: 253 C-IPHNG--------CRHGTCSTPWQ----CTCDEGWGGLFCDQDLNYCTHHSPCKNGAT 299
Query: 1430 CVQDSAGASTCACAAGYSGNG--IFCSEVD--PCAHGHGGCSP-----HANCTKVAPG-- 1478
C + TC C GY+G + SE D PC +G G C H C G
Sbjct: 300 CSNSGQRSYTCTCRPGYTGVDCELELSECDSNPCRNG-GSCKDQEDGYHCLCPPGYYGLH 358
Query: 1479 --QRTCTCQDGYMGDGELCQEIN-------SCLIHHGG--------------CHIHAECI 1515
T +C D +G C+E N C + G C +C+
Sbjct: 359 CEHSTLSCADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCL 418
Query: 1516 PTGPQQVSCSCREGYSGDGIRTCEL-LDPCSKNNGGCSPYATCKSTGDGQRTCTCDTAHT 1574
GP ++ C CR G++G CEL + C++N C+ TC +G CTC +
Sbjct: 419 NRGPSRM-CRCRPGFTG---TYCELHVSDCARN--PCAHGGTCHDLENG-LMCTCPAGFS 471
Query: 1575 VGDGLTCRARVGLE 1588
G C R ++
Sbjct: 472 ---GRRCEVRTSID 482
Score = 84.7 bits (208), Expect = 1e-15
Identities = 91/332 (27%), Positives = 118/332 (35%), Gaps = 56/332 (16%)
Query: 1945 GCHRNCVTTTWKPSCCPGHYGSECQA----CPGGPSSPCSDRGVCMDGMSGSGQCLCRSG 2000
GC +T W+ +C G G C C SPC + C + S C CR G
Sbjct: 258 GCRHGTCSTPWQCTCDEGWGGLFCDQDLNYCTH--HSPCKNGATCSNSGQRSYTCTCRPG 315
Query: 2001 FAGTACELCAPGAFGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPVC 2060
+ G CEL C + C G C + G C C G+ G CE
Sbjct: 316 YTGVDCELEL-----SECDSNPCRNGGSCKDQEDGY-HCLCPPGYYGLHCE--HSTLSCA 367
Query: 2061 TPPCAPEAVCRAGN-----SCECSLGYEGDGRVCTVADLCQDGHGGCSEHANCSQVGTMV 2115
PC CR N +CEC + G V D C C+ C G
Sbjct: 368 DSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKV-DRCTS--NPCANGGQCLNRGPSR 424
Query: 2116 TCTCLPDYEGDGWSCR----ARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGDGL 2171
C C P + G ARNPC H G C + N L C C AG+ G
Sbjct: 425 MCRCRPGFTGTYCELHVSDCARNPC--AHGGTCHDLENGL-------MCTCPAGF--SGR 473
Query: 2172 QCLEESEPPVDRCLGQPPPCHSDAMC-TDLHFQEKRAGVFHLQATSGPYGLNFSEAEAAC 2230
+C E +D C PC + A C TDL + PYG + C
Sbjct: 474 RC--EVRTSIDACASS--PCFNRATCYTDLSTD--------TFVCNCPYGF----VGSRC 517
Query: 2231 EAQGAVLASFPQLSAAQQLGFH--LCLMGWLA 2260
E + SFP ++ + +G L L+G +A
Sbjct: 518 EFPVGLPPSFPWVAVSLGVGLAVLLVLLGMVA 549
Score = 82.0 bits (201), Expect = 7e-15
Identities = 78/251 (31%), Positives = 91/251 (36%), Gaps = 51/251 (20%)
Query: 1958 SCCPGHYGSECQACPGGPSSPCSDRGVCMDGMSGSGQCLCRSGFAGTACELCAPGAFGPH 2017
SC PG G CQ P S G C S +CLCR G+ G C C P
Sbjct: 207 SCLPGWTGEYCQQ-PICLSGCHEQNGYC----SKPAECLCRPGWQGRLCNECIPH----- 256
Query: 2018 CQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPVCT--PPCAPEAVC----R 2071
CR HG C C CDEGW G C+ L CT PC A C +
Sbjct: 257 -NGCR---HGTCST----PWQCTCDEGWGGLFCDQDLN---YCTHHSPCKNGATCSNSGQ 305
Query: 2072 AGNSCECSLGYEGDGRVCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPDYEG-----D 2126
+C C GY G V +L + C +C C C P Y G
Sbjct: 306 RSYTCTCRPGYTG---VDCELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHS 362
Query: 2127 GWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGDGLQCLEESEPPVDRCLG 2186
SC A +PC +G G C E + G N CEC + G E VDRC
Sbjct: 363 TLSC-ADSPCFNG--GSCRER----NQGAN-YACECPPNFTG------SNCEKKVDRCTS 408
Query: 2187 QPPPCHSDAMC 2197
PC + C
Sbjct: 409 N--PCANGGQC 417
Score = 77.0 bits (188), Expect = 2e-13
Identities = 82/304 (26%), Positives = 109/304 (35%), Gaps = 71/304 (23%)
Query: 711 CNQTIMEQGC----CKGFFGPDCTQCPGGF-----------SNPCYGKGNCSDGIQGNGA 755
CN+ I GC C + C + GG +PC CS+ Q +
Sbjct: 250 CNECIPHNGCRHGTCSTPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYT 309
Query: 756 CLCFPDYKGIACHI----C-SNPNKHGEQCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGF 810
C C P Y G+ C + C SNP ++G C++ H LC PG+
Sbjct: 310 CTCRPGYTGVDCELELSECDSNPCRNGGSCKDQEDGYHCLCP---------------PGY 354
Query: 811 SGRFCNESMGDCGPTGLAQHCHLHARCVSQEGVAR--CRCLDGFEGDGFS-----CTPSN 863
G C S C + C C + A C C F G CT SN
Sbjct: 355 YGLHCEHSTLSCADSP----CFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRCT-SN 409
Query: 864 PCSHPDR---GGCSENAECVPGSLGTHHCTCHKGWSGDGRVCVAIDECELDMRGGCHTDA 920
PC++ + G S C PG GT+ C H + +C R C
Sbjct: 410 PCANGGQCLNRGPSRMCRCRPGFTGTY-CELH------------VSDCA---RNPCAHGG 453
Query: 921 LCSYVGPGQSRCTCKLGFAGDGYQC-SPIDPCRAGNGGCHGLATCRA-VGGGQRVCTCPP 978
C + G CTC GF+G + + ID C + C ATC + VC CP
Sbjct: 454 TCHDLENGLM-CTCPAGFSGRRCEVRTSIDAC--ASSPCFNRATCYTDLSTDTFVCNCPY 510
Query: 979 GFGG 982
GF G
Sbjct: 511 GFVG 514
Score = 75.1 bits (183), Expect = 8e-13
Identities = 82/305 (26%), Positives = 109/305 (35%), Gaps = 45/305 (14%)
Query: 693 YIHDPTG-LNVLKKGCASYCNQTIMEQGCCK--GFFGP--DCTQCPGG---FSNPCYGKG 744
Y+ P G L+ L YC Q I GC + G+ +C PG N C
Sbjct: 198 YVCQPDGNLSCLPGWTGEYCQQPICLSGCHEQNGYCSKPAECLCRPGWQGRLCNECIPHN 257
Query: 745 NCSDGIQGNG-ACLCFPDYKGIACHICSNPNKHGEQCQEDCGCVHGLCDNRPGSGGVCQQ 803
C G C C + G+ C N H C+ C + SG
Sbjct: 258 GCRHGTCSTPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSN--------SGQRSYT 309
Query: 804 GTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEG-----DGFS 858
TC PG++G C + +C + C C QE C C G+ G S
Sbjct: 310 CTCRPGYTGVDCELELSECD----SNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLS 365
Query: 859 CTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGRVCVA-IDECELDMRGGCH 917
C S PC + G C E + + C C ++G C +D C + C
Sbjct: 366 CADS-PCFNG--GSCRERNQGA-----NYACECPPNFTGSN--CEKKVDRCTSNP---CA 412
Query: 918 TDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCP 977
C GP + C C+ GF G + D R N HG TC + G +CTCP
Sbjct: 413 NGGQCLNRGPSRM-CRCRPGFTGTYCELHVSDCAR--NPCAHG-GTCHDLENGL-MCTCP 467
Query: 978 PGFGG 982
GF G
Sbjct: 468 AGFSG 472
Score = 70.1 bits (170), Expect = 3e-11
Identities = 85/305 (27%), Positives = 119/305 (39%), Gaps = 62/305 (20%)
Query: 1306 GCSY-TCAKKIQVPDCCPGFFGTLCE----------PCPGGLGGVCSGHGQCQDRFLGSG 1354
GC + TC+ Q C G+ G C+ PC G CS GQ S
Sbjct: 258 GCRHGTCSTPWQCT-CDEGWGGLFCDQDLNYCTHHSPCKNG--ATCSNSGQ------RSY 308
Query: 1355 ECHCHEGFHGTACEVCELGRYGPNCTGVCDCAHG-LCQEGLQGDG-SCVCNVGWQGLRCD 1412
C C G+ G CE+ EL N C +G C++ Q DG C+C G+ GL C+
Sbjct: 309 TCTCRPGYTGVDCEL-ELSECDSN-----PCRNGGSCKD--QEDGYHCLCPPGYYGLHCE 360
Query: 1413 QKITSPQCPRKCDPNANCVQDSAGAS-TCACAAGYSGNGIFCSEVDPCAHGHGGCSPHAN 1471
S C +C + + GA+ C C ++G+ +VD C C+
Sbjct: 361 HSTLSC-ADSPCFNGGSCRERNQGANYACECPPNFTGSNCE-KKVDRCTSNP--CANGGQ 416
Query: 1472 CTKVAPGQRTCTCQDGYMGDGELCQ-EINSCL----IHHGGCHIHAECIPTGPQQVSCSC 1526
C P R C C+ G+ G C+ ++ C H G CH + G + C+C
Sbjct: 417 CLNRGPS-RMCRCRPGFTGT--YCELHVSDCARNPCAHGGTCHD----LENG---LMCTC 466
Query: 1527 REGYSGDGIRTCEL---LDPCSKNNGGCSPYATC-KSTGDGQRTCTCDTAHTVGDGLTCR 1582
G+SG R CE+ +D C+ + C ATC C C G C
Sbjct: 467 PAGFSG---RRCEVRTSIDACA--SSPCFNRATCYTDLSTDTFVCNCPYGFV---GSRCE 518
Query: 1583 ARVGL 1587
VGL
Sbjct: 519 FPVGL 523
Score = 69.3 bits (168), Expect = 5e-11
Identities = 68/230 (29%), Positives = 92/230 (40%), Gaps = 63/230 (27%)
Query: 769 ICSNPNKHGEQCQEDCGCVHGLCDNRPGSGG--VCQQG---TCAPGFSGRFCNESMGDCG 823
ICS+ N +G+ C LC R G VCQ +C PG++G +C + + G
Sbjct: 174 ICSD-NYYGDNCSR-------LCKKRNDHFGHYVCQPDGNLSCLPGWTGEYCQQPICLSG 225
Query: 824 PTGLAQHCHLHARCVSQEGVARCRCLDGFEGDGFS-CTPSNPCSHPDRGGCSENAECVPG 882
CH S+ A C C G++G + C P N C H G CS
Sbjct: 226 -------CHEQNGYCSKP--AECLCRPGWQGRLCNECIPHNGCRH---GTCST------- 266
Query: 883 SLGTHHCTCHKGWSGDGRVCVAIDECELDM-----RGGCHTDALCSYVGPGQSRCTCKLG 937
CTC +GW G C+ D+ C A CS G CTC+ G
Sbjct: 267 ---PWQCTCDEGWGG--------LFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPG 315
Query: 938 FAG-----DGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGFGG 982
+ G + +C +PCR NGG +C+ G C CPPG+ G
Sbjct: 316 YTGVDCELELSECDS-NPCR--NGG-----SCKDQEDGYH-CLCPPGYYG 356
Score = 68.9 bits (167), Expect = 6e-11
Identities = 45/148 (30%), Positives = 59/148 (39%), Gaps = 13/148 (8%)
Query: 1943 GRGCHRNCVTTTWKPSCCPGHYGSECQA-CPGGPSSPCSDRGVCMDGMSGSGQCLCRSGF 2001
G C + C P GS C+ S+PC++ G C++ S C CR GF
Sbjct: 374 GGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLN-RGPSRMCRCRPGF 432
Query: 2002 AGTACELCAPGAFGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPVCT 2061
GT CEL C C G C + L C C G++G RCEV+ + +
Sbjct: 433 TGTYCELHVSD-----CARNPCAHGGTCHD-LENGLMCTCPAGFSGRRCEVRTSIDACAS 486
Query: 2062 PPCAPEAVCRAGNS-----CECSLGYEG 2084
PC A C S C C G+ G
Sbjct: 487 SPCFNRATCYTDLSTDTFVCNCPYGFVG 514
Score = 65.5 bits (158), Expect = 7e-10
Identities = 64/248 (25%), Positives = 85/248 (34%), Gaps = 42/248 (16%)
Query: 32 CDVKTTFVTH-VPCTSCAAIKKQTCPSGWLRELPDQITQDCRYEVQLGGSMVSMSGCRRK 90
CD + TH PC + A S P DC E+ S +G K
Sbjct: 281 CDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCK 340
Query: 91 CRKQVVQKACCPGYWGSRC-HECPGGAETPCNGHGTCLD-GMDRNGTCVCQENFRGSACQ 148
++ C PGY+G C H A++PC G+C + N C C NF GS C+
Sbjct: 341 DQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGANYACECPPNFTGSNCE 400
Query: 149 ECQD-------------------------PNRFGPDCQ---SVCS---CVHGVCNHGPRG 177
+ D P G C+ S C+ C HG H
Sbjct: 401 KKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDCARNPCAHGGTCHDLEN 460
Query: 178 DGSCLCFAGYTGPHCD--QELPVCQELRCPQNTQC----SAEAPSCRCLPGYTQQGSECR 231
C C AG++G C+ + C C C S + C C G+ GS C
Sbjct: 461 GLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFV--GSRCE 518
Query: 232 APNPCWPS 239
P PS
Sbjct: 519 FPVGLPPS 526
Score = 62.8 bits (151), Expect = 4e-09
Identities = 46/154 (29%), Positives = 61/154 (39%), Gaps = 27/154 (17%)
Query: 1304 SRGCSYTCAKKIQVPDCCPGFFGTLCEP-CPGGLGGVCSGHGQCQDRFLGSGECHCHEGF 1362
++G +Y C +C P F G+ CE C+ GQC +R S C C GF
Sbjct: 381 NQGANYAC-------ECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRG-PSRMCRCRPGF 432
Query: 1363 HGTACEVCELGRYGPNCTGVCDCAHGLCQEG-----LQGDGSCVCNVGWQGLRCDQKITS 1417
GT CE+ V DCA C G L+ C C G+ G RC+ + +
Sbjct: 433 TGTYCEL-----------HVSDCARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSI 481
Query: 1418 PQCPRK-CDPNANCVQD-SAGASTCACAAGYSGN 1449
C C A C D S C C G+ G+
Sbjct: 482 DACASSPCFNRATCYTDLSTDTFVCNCPYGFVGS 515
Score = 51.2 bits (121), Expect = 1e-05
Identities = 54/221 (24%), Positives = 71/221 (32%), Gaps = 83/221 (37%)
Query: 137 VCQENFRGSACQE-CQDPN-RFGPDCQSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQ 194
+C +N+ G C C+ N FG H VC + DG+ C G+TG +C Q
Sbjct: 174 ICSDNYYGDNCSRLCKKRNDHFG----------HYVC----QPDGNLSCLPGWTGEYCQQ 219
Query: 195 ELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQG---SECRAPNPCWPSPCSLLAQCSVSP 251
P+C QN CS A C C PG+ QG +EC N C CS QC+
Sbjct: 220 --PICLSGCHEQNGYCSKPA-ECLCRPGW--QGRLCNECIPHNGCRHGTCSTPWQCT--- 271
Query: 252 KGQAQCHCPENYHGDGMVCLPKDPCTDNLGG--CPSNSTLCVYQKPGQAFCTCRPGLVSI 309
C + GG C + C + P
Sbjct: 272 ------------------------CDEGWGGLFCDQDLNYCTHHSP-------------- 293
Query: 310 NSNASAGCFAFCSPFSCDRSATCQVTADGKTSCVCRESEVG 350
C ATC + +C CR G
Sbjct: 294 ----------------CKNGATCSNSGQRSYTCTCRPGYTG 318
>gi|75709198 nephronectin [Homo sapiens]
Length = 565
Score = 94.7 bits (234), Expect = 1e-18
Identities = 71/220 (32%), Positives = 93/220 (42%), Gaps = 32/220 (14%)
Query: 779 QCQEDCG--CVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHAR 836
QCQ C C HG C + C PG++G+ CN+ + +CG L H R
Sbjct: 55 QCQPVCQPRCKHGECIGP-------NKCKCHPGYAGKTCNQDLNECG---LKPRPCKH-R 103
Query: 837 CVSQEGVARCRCLDGFE--GDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKG 894
C++ G +C CL+G+ DG SC+ + CS C + V G + C C
Sbjct: 104 CMNTYGSYKCYCLNGYMLMPDG-SCSSALTCS---MANCQYGCDVVKGQI---RCQCPSP 156
Query: 895 W---SGDGRVCVAIDECELDMRGGCHTDALCSYVGPGQSRCTCKLGF----AGDGYQCSP 947
+ DGR CV +DEC R C C G C C GF G YQC
Sbjct: 157 GLQLAPDGRTCVDVDECATG-RASCPRFRQCVNTF-GSYICKCHKGFDLMYIGGKYQCHD 214
Query: 948 IDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGFGGDGFSC 987
ID C G C A C + G + C C G+ GDG +C
Sbjct: 215 IDECSLGQYQCSSFARCYNIRGSYK-CKCKEGYQGDGLTC 253
Score = 77.0 bits (188), Expect = 2e-13
Identities = 65/208 (31%), Positives = 75/208 (36%), Gaps = 22/208 (10%)
Query: 160 CQSVCS--CVHGVCNHGPRGDGSCLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAPS- 216
CQ VC C HG C G C C GY G C+Q+L C P +C S
Sbjct: 56 CQPVCQPRCKHGECI----GPNKCKCHPGYAGKTCNQDLNECGLKPRPCKHRCMNTYGSY 111
Query: 217 -CRCLPGY-TQQGSECRAPNPCWPSPCSLLAQCSVSPKGQAQCHCPE---NYHGDGMVCL 271
C CL GY C + C + C C V KGQ +C CP DG C+
Sbjct: 112 KCYCLNGYMLMPDGSCSSALTCSMANCQY--GCDV-VKGQIRCQCPSPGLQLAPDGRTCV 168
Query: 272 PKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPG--LVSINSNASAGCFAFCS--PFSCD 327
D C CP CV G C C G L+ I CS + C
Sbjct: 169 DVDECATGRASCP-RFRQCV-NTFGSYICKCHKGFDLMYIGGKYQCHDIDECSLGQYQCS 226
Query: 328 RSATCQVTADGKTSCVCRESEVGDGRAC 355
A C G C C+E GDG C
Sbjct: 227 SFARC-YNIRGSYKCKCKEGYQGDGLTC 253
Score = 75.9 bits (185), Expect = 5e-13
Identities = 67/235 (28%), Positives = 85/235 (36%), Gaps = 39/235 (16%)
Query: 1319 DCCPGFFGTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTAC--EVCELGRYG 1376
DCC G+ C C HG+C +G +C CH G+ G C ++ E G
Sbjct: 43 DCCWGWARQSWGQCQPVCQPRCK-HGEC----IGPNKCKCHPGYAGKTCNQDLNECGLKP 97
Query: 1377 PNCTGVCDCAHG----LCQEG--LQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANC 1430
C C +G C G L DGSC L C C CD
Sbjct: 98 RPCKHRCMNTYGSYKCYCLNGYMLMPDGSCS-----SALTCSMA----NCQYGCDV---- 144
Query: 1431 VQDSAGASTCACAAG---YSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDG 1487
G C C + + +G C +VD CA G C C G C C G
Sbjct: 145 ---VKGQIRCQCPSPGLQLAPDGRTCVDVDECATGRASCPRFRQCVNTF-GSYICKCHKG 200
Query: 1488 ----YMGDGELCQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTC 1538
Y+G C +I+ C + C A C C C+EGY GDG+ TC
Sbjct: 201 FDLMYIGGKYQCHDIDECSLGQYQCSSFARCYNIRGSY-KCKCKEGYQGDGL-TC 253
Score = 75.9 bits (185), Expect = 5e-13
Identities = 62/218 (28%), Positives = 86/218 (39%), Gaps = 35/218 (16%)
Query: 1379 CTGVCD--CAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAG 1436
C VC C HG C G C C+ G+ G C+Q + +C K P + ++ G
Sbjct: 56 CQPVCQPRCKHGECI----GPNKCKCHPGYAGKTCNQDLN--ECGLKPRPCKHRCMNTYG 109
Query: 1437 ASTCACAAGY----SGNGIFCSEVDPCAHGHGGCSPHANCT---KVAPGQRTCTCQDGYM 1489
+ C C GY G+ CS C+ ANC V GQ C C +
Sbjct: 110 SYKCYCLNGYMLMPDGS---CSSALTCSM--------ANCQYGCDVVKGQIRCQCPSPGL 158
Query: 1490 G---DGELCQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSG---DGIRTCELLDP 1543
DG C +++ C C +C+ T + C C +G+ G C +D
Sbjct: 159 QLAPDGRTCVDVDECATGRASCPRFRQCVNTFGSYI-CKCHKGFDLMYIGGKYQCHDIDE 217
Query: 1544 CSKNNGGCSPYATCKSTGDGQRTCTCDTAHTVGDGLTC 1581
CS CS +A C + G C C + GDGLTC
Sbjct: 218 CSLGQYQCSSFARCYNI-RGSYKCKCKEGYQ-GDGLTC 253
Score = 61.2 bits (147), Expect = 1e-08
Identities = 63/232 (27%), Positives = 82/232 (35%), Gaps = 36/232 (15%)
Query: 1964 YGSECQACPG------GPSSP-CSDRGVCMDGMS-GSGQCLCRSGFAGTAC--ELCAPGA 2013
YG C G G P C R C G G +C C G+AG C +L G
Sbjct: 38 YGGRIDCCWGWARQSWGQCQPVCQPR--CKHGECIGPNKCKCHPGYAGKTCNQDLNECGL 95
Query: 2014 FGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWT---GPRCEVQLELQPV-CTPPCAPEAV 2069
C+ RC GS C+C G+ C L C C V
Sbjct: 96 KPRPCKH-RCM-------NTYGSYKCYCLNGYMLMPDGSCSSALTCSMANCQYGCD---V 144
Query: 2070 CRAGNSCEC---SLGYEGDGRVCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPDYE-- 2124
+ C+C L DGR C D C G C C C C ++
Sbjct: 145 VKGQIRCQCPSPGLQLAPDGRTCVDVDECATGRASCPRFRQCVNTFGSYICKCHKGFDLM 204
Query: 2125 --GDGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGDGLQCL 2174
G + C + C+ G + CS A C + + +C+C GY GDGL C+
Sbjct: 205 YIGGKYQCHDIDECSLG-QYQCSSFARCYNI-RGSYKCKCKEGYQGDGLTCV 254
Score = 59.3 bits (142), Expect = 5e-08
Identities = 64/237 (27%), Positives = 88/237 (37%), Gaps = 51/237 (21%)
Query: 720 CCKGFFGPDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSN------- 772
CC G+ QC C G C G C C P Y G C+ N
Sbjct: 44 CCWGWARQSWGQCQPVCQPRCK-HGECI----GPNKCKCHPGYAGKTCNQDLNECGLKPR 98
Query: 773 PNKHGEQCQED-----CGCVHG---LCDNRPGSGGVCQQGTC----------------AP 808
P KH +C C C++G + D S C C +P
Sbjct: 99 PCKH--RCMNTYGSYKCYCLNGYMLMPDGSCSSALTCSMANCQYGCDVVKGQIRCQCPSP 156
Query: 809 GFS----GRFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFE----GDGFSCT 860
G GR C + + +C TG A C +CV+ G C+C GF+ G + C
Sbjct: 157 GLQLAPDGRTCVD-VDECA-TGRAS-CPRFRQCVNTFGSYICKCHKGFDLMYIGGKYQCH 213
Query: 861 PSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGRVCVAIDECELDMRGGCH 917
+ CS + CS A C G++ C C +G+ GDG CV I + ++ G H
Sbjct: 214 DIDECSL-GQYQCSSFARCY-NIRGSYKCKCKEGYQGDGLTCVYIPKVMIEPSGPIH 268
Score = 47.8 bits (112), Expect = 1e-04
Identities = 59/240 (24%), Positives = 83/240 (34%), Gaps = 52/240 (21%)
Query: 55 CPSGWLRELPDQITQDCRYEVQLGGSMVSMSGCRRKCRKQVVQKACCPGYWGSRCH---- 110
C GW R+ Q C+ + G + + C+ C PGY G C+
Sbjct: 44 CCWGWARQSWGQCQPVCQPRCK-HGECIGPNKCK-----------CHPGYAGKTCNQDLN 91
Query: 111 ECPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPD--CQSVCSCVH 168
EC G PC C + C C + PD C S +C
Sbjct: 92 EC-GLKPRPCKHR--------------CMNTYGSYKCY-CLNGYMLMPDGSCSSALTCSM 135
Query: 169 GVCNHG---PRGDGSCLCFA-----GYTGPHC-DQELPVCQELRCPQNTQCSAEAPS--C 217
C +G +G C C + G C D + CP+ QC S C
Sbjct: 136 ANCQYGCDVVKGQIRCQCPSPGLQLAPDGRTCVDVDECATGRASCPRFRQCVNTFGSYIC 195
Query: 218 RCLPG----YTQQGSECRAPNPC--WPSPCSLLAQCSVSPKGQAQCHCPENYHGDGMVCL 271
+C G Y +C + C CS A+C + +G +C C E Y GDG+ C+
Sbjct: 196 KCHKGFDLMYIGGKYQCHDIDECSLGQYQCSSFARC-YNIRGSYKCKCKEGYQGDGLTCV 254
Score = 45.4 bits (106), Expect = 7e-04
Identities = 50/188 (26%), Positives = 71/188 (37%), Gaps = 30/188 (15%)
Query: 1388 GLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTCACAAGYS 1447
GLC+ G G C GW Q P C +C + C+ G + C C GY+
Sbjct: 34 GLCRYG----GRIDCCWGWARQSWGQ--CQPVCQPRCK-HGECI----GPNKCKCHPGYA 82
Query: 1448 GNGIFCSE-VDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYM--GDGELCQEINSCLIH 1504
G C++ ++ C C T G C C +GYM DG C +C +
Sbjct: 83 GKT--CNQDLNECGLKPRPCKHRCMNTY---GSYKCYCLNGYMLMPDGS-CSSALTCSM- 135
Query: 1505 HGGCHIHAECIPTGPQQVSCSCREG---YSGDGIRTCELLDPCSKNNGGCSPYATCKSTG 1561
C + + Q+ C C + DG RTC +D C+ C + C +T
Sbjct: 136 -ANCQYGCDVVKG---QIRCQCPSPGLQLAPDG-RTCVDVDECATGRASCPRFRQCVNT- 189
Query: 1562 DGQRTCTC 1569
G C C
Sbjct: 190 FGSYICKC 197
Score = 41.6 bits (96), Expect = 0.010
Identities = 54/199 (27%), Positives = 76/199 (38%), Gaps = 47/199 (23%)
Query: 711 CNQTIMEQGC--------CKGFFGPDCTQCPGGFSNPCYGKGNCSDGIQGNGA-CLCFPD 761
CNQ + E G C +G C G+ G+CS + + A C D
Sbjct: 86 CNQDLNECGLKPRPCKHRCMNTYGSYKCYCLNGYM--LMPDGSCSSALTCSMANCQYGCD 143
Query: 762 Y-KG-IACHICSNPNKH----GEQCQEDCGCVHGL--------CDNRPGSGGVCQQGTCA 807
KG I C C +P G C + C G C N GS +C+ C
Sbjct: 144 VVKGQIRCQ-CPSPGLQLAPDGRTCVDVDECATGRASCPRFRQCVNTFGSY-ICK---CH 198
Query: 808 PGFS-----GRFCNESMGDCGPTGLAQH-CHLHARCVSQEGVARCRCLDGFEGDGFSCT- 860
GF G++ + +C L Q+ C ARC + G +C+C +G++GDG +C
Sbjct: 199 KGFDLMYIGGKYQCHDIDECS---LGQYQCSSFARCYNIRGSYKCKCKEGYQGDGLTCVY 255
Query: 861 -------PSNPCSHPDRGG 872
PS P P G
Sbjct: 256 IPKVMIEPSGPIHVPKGNG 274
>gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo
sapiens]
Length = 3118
Score = 93.6 bits (231), Expect = 2e-18
Identities = 128/493 (25%), Positives = 170/493 (34%), Gaps = 129/493 (26%)
Query: 1851 PFEGGLAYGIDQLLEPPGL-GARCDHFETRPLRLNTCSICGLEPPCPEGSQEQGSPEACW 1909
P +G +A ++ PPG G+ C+ R R+N G+ PC Q G E+C
Sbjct: 712 PTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPC----QCFGHAESCD 767
Query: 1910 RFYPKFWTSPPLHSLGLRSVWVHPSLWGRP-QGLGRGCHR-----NCVTTTWKPSC---- 1959
+ H+ G P +G P +G C N + + P+C
Sbjct: 768 DVTGECLNCKD-HTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDR 826
Query: 1960 --------CP-GHYGSECQAC----------PGGPSSPCSDRGVCMDGM---------SG 1991
CP G+ G C+ C PGG PC C D + S
Sbjct: 827 SLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQ----CNDNLDFSIPGSCDSL 882
Query: 1992 SGQCL-CRSGFAGTACELCAPGAFG-----PHCQACRCTVHGRCDEGL-GGSGSCFCDEG 2044
SG CL C+ G G CELCA G FG +CQ CRC G E +G C C
Sbjct: 883 SGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRAN 942
Query: 2045 WTGPRCE------VQLELQPVCTPPC------APEAVCRAGNSCECSLGYEGDGRVCTVA 2092
G RC+ L+ C PC + C C C G G+ C
Sbjct: 943 VQGQRCDKCKAGTFGLQSARGCV-PCNCNSFGSKSFDCEESGQCWCQPGV--TGKKC--- 996
Query: 2093 DLCQDGH-----GGCSEHANCSQVGTMV-----TCTCLPDYEGDGWSCRARNPCTDGH-- 2140
D C G+ GGC+ CS +G C C P+ G+ C P T GH
Sbjct: 997 DRCAHGYFNFQEGGCTA-CECSHLGNNCDPKTGRCICPPNTIGE--KCSKCAPNTWGHSI 1053
Query: 2141 RGGCSEHANCLSTG-------LNTRRCECHAGYVGDGLQCLE------------------ 2175
GC + NC + G +NT +C CH + G +C E
Sbjct: 1054 TTGC-KACNCSTVGSLDFQCNVNTGQCNCHPKF--SGAKCTECSRGHWNYPRCNLCDCFL 1110
Query: 2176 --------ESEPPVDRCLGQPPPCHSDAMCTDLHFQEKRAGVFHLQATSGPYGLN----F 2223
+SE C Q C +H R G F L A P G + F
Sbjct: 1111 PGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDA-KNPLGCSSCYCF 1169
Query: 2224 SEAEAACEAQGAV 2236
EA+G +
Sbjct: 1170 GTTTQCSEAKGLI 1182
Score = 68.9 bits (167), Expect = 6e-11
Identities = 76/277 (27%), Positives = 96/277 (34%), Gaps = 49/277 (17%)
Query: 100 CCPGYWGSRCHEC-----------PGGAETPCNGHGTCLDGMDRNGTCV-CQENFRGSAC 147
C PGY GS C C GG PC G D G C+ C+++ G C
Sbjct: 726 CPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLNCKDHTGGPYC 785
Query: 148 QECQDPNRFG-------PDCQSVCSCVHGVCN-------HGPRGDGSCL--CFAGYTGPH 191
+C P +G DCQ C+C + + H R G C GYTGP
Sbjct: 786 DKCL-PGFYGEPTKGTSEDCQP-CACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPR 843
Query: 192 CDQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQGSECRAPNPCWPSPCSLLAQCSVSP 251
C+ RC + P C P + P C S L C
Sbjct: 844 CE---------RCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLI-CKPGT 893
Query: 252 KGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPGLVSIN- 310
G+ C + Y GD + PC N GG S S +C + + GQ C CR +
Sbjct: 894 TGRYCELCADGYFGDAVDAKNCQPCRCNAGG--SFSEVC-HSQTGQ--CECRANVQGQRC 948
Query: 311 SNASAGCFAFCSPFSCDRSATCQVTADGKTSCVCRES 347
AG F S C C + G S C ES
Sbjct: 949 DKCKAGTFGLQSARGC---VPCNCNSFGSKSFDCEES 982
Score = 64.7 bits (156), Expect = 1e-09
Identities = 67/291 (23%), Positives = 92/291 (31%), Gaps = 52/291 (17%)
Query: 53 QTCPSGWLRELPD-QITQDCRYEVQLGGSMVSMSGCRRKCRKQVVQKACCPGYWGSRCHE 111
+ C G+ + D + Q CR GGS + C Q Q C G RC +
Sbjct: 899 ELCADGYFGDAVDAKNCQPCRCNA--GGSFSEV------CHSQTGQCECRANVQGQRCDK 950
Query: 112 CPGGA----------ETPCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPN-RFGPDC 160
C G CN G+ + +G C CQ G C C F
Sbjct: 951 CKAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGG 1010
Query: 161 QSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQELP---------VCQELRCPQ----N 207
+ C C H N P+ G C+C G C + P C+ C +
Sbjct: 1011 CTACECSHLGNNCDPK-TGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLD 1069
Query: 208 TQCSAEAPSCRCLPGYTQQGSEC-RAPNPCWPSPCSLLAQCSVSPKGQAQCHCPENYHGD 266
QC+ C C P ++ G++C W P L C + C
Sbjct: 1070 FQCNVNTGQCNCHPKFS--GAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETK---- 1123
Query: 267 GMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPGLVSINSNASAGC 317
K C+D G C C G CRPG +++ GC
Sbjct: 1124 ------KCSCSDQTGQC-----TCKVNVEGIHCDRCRPGKFGLDAKNPLGC 1163
Score = 63.5 bits (153), Expect = 3e-09
Identities = 79/289 (27%), Positives = 101/289 (34%), Gaps = 60/289 (20%)
Query: 1312 AKKIQVPDCCPGFFGTLCEPC------PGG--LGGVCS-----GHGQ-CQDRFLGSGEC- 1356
A ++V C PG+ G+ CE C G GG+C GH + C D +GEC
Sbjct: 718 AAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDD---VTGECL 774
Query: 1357 HCHEGFHGTACEVCELGRYGPNCTGVC-DCAHGLCQEGLQGDG-SCVCNVGWQ-GLRCD- 1412
+C + G C+ C G YG G DC C + + S C++ GL CD
Sbjct: 775 NCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDG 834
Query: 1413 --QKITSPQCPRKCDPNANCVQDSAGASTCACAAGYSGN-GIFCSEVDPCAHGH------ 1463
T P+C R CA GY G + PC
Sbjct: 835 CPVGYTGPRCER-------------------CAEGYFGQPSVPGGSCQPCQCNDNLDFSI 875
Query: 1464 -GGC-SPHANCTKVAPGQ--RTC-TCQDGYMGDGELCQEINSCLIHHGGCHIHAECIPTG 1518
G C S +C PG R C C DGY GD + C + GG TG
Sbjct: 876 PGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTG 935
Query: 1519 PQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKSTGDGQRTC 1567
C CR G C+ ++ GC P C S G C
Sbjct: 936 ----QCECRANVQGQRCDKCKAGTFGLQSARGCVP-CNCNSFGSKSFDC 979
Score = 62.0 bits (149), Expect = 7e-09
Identities = 92/368 (25%), Positives = 124/368 (33%), Gaps = 90/368 (24%)
Query: 1264 HAEALRE---KCVNCTRRF------RCTQGFQLQDTPRKS-----CVYRSGF---SFSRG 1306
HAE+ + +C+NC +C GF + T S C +FS
Sbjct: 762 HAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPT 821
Query: 1307 CSYTCAKKIQVPDCCPGFFGTLCEPCPGGLGGVCSGHG------QCQDR--FLGSGECH- 1357
C + + C G+ G CE C G G S G QC D F G C
Sbjct: 822 CHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDS 881
Query: 1358 -------CHEGFHGTACEVCELGRYG-----PNCTGV-CDCAHGLCQEGLQGDGSCVCNV 1404
C G G CE+C G +G NC C+ + G C C
Sbjct: 882 LSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRA 941
Query: 1405 GWQGLRCDQKITSP---QCPRKCDPNANCVQ------DSAGASTCACAAGYSGNGIFCSE 1455
QG RCD+ Q R C P NC D + C C G +G +
Sbjct: 942 NVQGQRCDKCKAGTFGLQSARGCVP-CNCNSFGSKSFDCEESGQCWCQPGVTG-----KK 995
Query: 1456 VDPCAHGH-----GGCSPHANCTKVA----PGQRTCTCQDGYMGDGELCQEINSCLIHHG 1506
D CAHG+ GGC+ C+ + P C C +G ++ + C +
Sbjct: 996 CDRCAHGYFNFQEGGCTA-CECSHLGNNCDPKTGRCICPPNTIG-----EKCSKCAPNTW 1049
Query: 1507 GCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLD-PCSKNNGGCSPYATCKSTGDGQR 1565
G I TG + +CS T LD C+ N G C+ C G +
Sbjct: 1050 G-----HSITTGCKACNCS-----------TVGSLDFQCNVNTGQCN----CHPKFSGAK 1089
Query: 1566 TCTCDTAH 1573
C H
Sbjct: 1090 CTECSRGH 1097
Score = 61.2 bits (147), Expect = 1e-08
Identities = 69/260 (26%), Positives = 82/260 (31%), Gaps = 59/260 (22%)
Query: 756 CLCFPDYKGIACHICSNPNKHG---------EQCQ-----EDCGCVHGLCDNRPGSGGVC 801
C C P Y G +C C ++ E CQ E C V G C N G
Sbjct: 724 CQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLNCKDHTGGP 783
Query: 802 QQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGDGFSCTP 861
C PGF G + DC P C C + FS
Sbjct: 784 YCDKCLPGFYGEPTKGTSEDCQP---------------------CACPLNIPSNNFS--- 819
Query: 862 SNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGRV-------CVAIDECELDMRG 914
P H DR C G G C +G+ G V C D + + G
Sbjct: 820 --PTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPG 877
Query: 915 GCHT-DALCSYVGPGQSRCTCKL---GFAGDGYQCSPIDPCRAGNGG-----CH---GLA 962
C + C PG + C+L G+ GD PCR GG CH G
Sbjct: 878 SCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQC 937
Query: 963 TCRAVGGGQRVCTCPPGFGG 982
CRA GQR C G G
Sbjct: 938 ECRANVQGQRCDKCKAGTFG 957
Score = 60.5 bits (145), Expect = 2e-08
Identities = 78/304 (25%), Positives = 99/304 (32%), Gaps = 90/304 (29%)
Query: 719 GCCKGFFGPDCTQC----------PGGFSNPCYGKGNCSDGIQG-----NGACL-CFPDY 762
GC G+ GP C +C PGG PC N I G +G+CL C P
Sbjct: 834 GCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGT 893
Query: 763 KGIACHICSN----PNKHGEQCQEDCGCVHG-----LCDNRPGSGGVCQQGTCAPGFSGR 813
G C +C++ + CQ C C G +C ++ G Q C G+
Sbjct: 894 TGRYCELCADGYFGDAVDAKNCQ-PCRCNAGGSFSEVCHSQTG------QCECRANVQGQ 946
Query: 814 FCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGC 873
C++ G GL S G C C + F F C S C
Sbjct: 947 RCDKC--KAGTFGLQ----------SARGCVPCNC-NSFGSKSFDCEESGQC-------- 985
Query: 874 SENAECVPGSLGTHHCTCHKGWSGDGRVCVAIDECELDMRGGCHTDALCSYVG----PGQ 929
C PG G C G+ GGC T CS++G P
Sbjct: 986 ----WCQPGVTGKKCDRCAHGYFN-------------FQEGGC-TACECSHLGNNCDPKT 1027
Query: 930 SRCTCKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRA-----------VGGGQRVCTCPP 978
RC C G+ +CS P G+ G C V GQ C C P
Sbjct: 1028 GRCICPPNTIGE--KCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQ--CNCHP 1083
Query: 979 GFGG 982
F G
Sbjct: 1084 KFSG 1087
Score = 54.7 bits (130), Expect = 1e-06
Identities = 36/112 (32%), Positives = 50/112 (44%), Gaps = 13/112 (11%)
Query: 1949 NCVTTT---WKPSCCPGHYGSECQACPGGPSSPCSDRGVCMDGMSGS------GQCLCRS 1999
NC T T ++P +Y CQ C P ++ VC+ + G C C++
Sbjct: 389 NCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNE--VCVKDEKHARRGLAPGSCHCKT 446
Query: 2000 GFAGTACELCAPGAFG-PHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRC 2050
GF G +C+ CA G G P C+AC C+ G +E G C C E G C
Sbjct: 447 GFGGVSCDRCARGYTGYPDCKACNCSGLGSKNED-PCFGPCICKENVEGGDC 497
Score = 50.4 bits (119), Expect = 2e-05
Identities = 36/111 (32%), Positives = 46/111 (41%), Gaps = 21/111 (18%)
Query: 1959 CCPGHYG------SECQ--ACPGGPSSPCSDRGVCMDGMSGSGQCLCRSGFAGTACELCA 2010
C G+YG ++CQ ACP SS +G+ C G+ G CE CA
Sbjct: 1451 CALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRGYEGQYCERCA 1510
Query: 2011 PGAFGP------HCQACRCTVHGR----CDEGLGGSGSCFCDEGWTGPRCE 2051
PG G CQ C C +G CD +G C C G TG +C+
Sbjct: 1511 PGYTGSPGNPGGSCQECECDPYGSLPVPCDP---VTGFCTCRPGATGRKCD 1558
Score = 49.7 bits (117), Expect = 4e-05
Identities = 57/241 (23%), Positives = 83/241 (34%), Gaps = 51/241 (21%)
Query: 1250 SGVLTVGSSR-CLHSHAEALREKCVNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRG-- 1306
+G + S+R C+ + + K +C +C + C + F+F G
Sbjct: 953 AGTFGLQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAH-GYFNFQEGGC 1011
Query: 1307 ----CSY---TCAKKIQVPDCCPGFFGTLCEPCPGGLGG--VCSGHGQCQDRFLGS---- 1353
CS+ C K C P G C C G + +G C +GS
Sbjct: 1012 TACECSHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQ 1071
Query: 1354 -----GECHCHEGFHGTACEVCELGRYG-PNCTGVCDC-----AHGLCQEGLQ------G 1396
G+C+CH F G C C G + P C +CDC C +
Sbjct: 1072 CNVNTGQCNCHPKFSGAKCTECSRGHWNYPRC-NLCDCFLPGTDATTCDSETKKCSCSDQ 1130
Query: 1397 DGSCVCNVGWQGLRCDQKITSPQCPRKCDPN--ANCVQDSAGASTCACAAGYSGNGIFCS 1454
G C C V +G+ CD +C P ++ G S+C C G CS
Sbjct: 1131 TGQCTCKVNVEGIHCD----------RCRPGKFGLDAKNPLGCSSCYC----FGTTTQCS 1176
Query: 1455 E 1455
E
Sbjct: 1177 E 1177
Score = 49.3 bits (116), Expect = 5e-05
Identities = 34/113 (30%), Positives = 45/113 (39%), Gaps = 15/113 (13%)
Query: 1315 IQVPDCCPGFFGTL---------CEPCP----GGLGGVCSGHGQCQDRFLGSGECHCHEG 1361
I C GFF C+PC G L VC + R L G CHC G
Sbjct: 388 INCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTG 447
Query: 1362 FHGTACEVCELGRYG-PNCTGVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQ 1413
F G +C+ C G G P+C C+C+ + G C+C +G C +
Sbjct: 448 FGGVSCDRCARGYTGYPDCK-ACNCSGLGSKNEDPCFGPCICKENVEGGDCSR 499
Score = 48.1 bits (113), Expect = 1e-04
Identities = 63/225 (28%), Positives = 79/225 (35%), Gaps = 63/225 (28%)
Query: 95 VVQKACCP-GYWGSRCHEC-PG--------GAETPCNGHGTCLDGMDRNGTCVCQENFRG 144
+++K CP GY G C C PG G TP GTC+ CQ N
Sbjct: 1376 LIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVP---------CQCNGHS 1426
Query: 145 SACQECQDPNRFGPDCQSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQELPV-CQELR 203
S C DP S+C C H GD C GY G + LP CQ+
Sbjct: 1427 SLC----DPET------SICQN----CQHHTAGDFCERCALGYYG--IVKGLPNDCQQCA 1470
Query: 204 CPQNTQCSAEAPSCRC--LPGYTQQGSECRAPNPCWPSPCSLLAQCSVSPKGQAQCHCPE 261
CP + + +PSC L Y +C+ P+G +C
Sbjct: 1471 CPLISSSNNFSPSCVAEGLDDY----------------------RCTACPRGYEGQYCER 1508
Query: 262 NYHG-DGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPG 305
G G P C + C +L V P FCTCRPG
Sbjct: 1509 CAPGYTGSPGNPGGSCQEC--ECDPYGSLPVPCDPVTGFCTCRPG 1551
Score = 47.4 bits (111), Expect = 2e-04
Identities = 29/94 (30%), Positives = 38/94 (40%), Gaps = 18/94 (19%)
Query: 100 CCPGYWG-SRCHEC----PGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPN 154
C G+W RC+ C PG T C+ D+ G C C+ N G C C+ P
Sbjct: 1093 CSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCR-PG 1151
Query: 155 RFGPDCQSVCSCVHGVCNHGPRGDGSCLCFAGYT 188
+FG D ++ P G SC CF T
Sbjct: 1152 KFGLDAKN------------PLGCSSCYCFGTTT 1173
Score = 44.7 bits (104), Expect = 0.001
Identities = 63/274 (22%), Positives = 89/274 (32%), Gaps = 98/274 (35%)
Query: 1960 CPGHYGSECQACPGGPSSPCSDRGVCMDGMSGSGQCLCRSGFAGTACELCAPG------- 2012
C GH +ACP +D + +C C G +C+ C PG
Sbjct: 289 CYGH----ARACP-------------LDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWR 331
Query: 2013 ----AFGPHCQACRCTVHGRCDE-------------------GLGGSGSCFCDEGWTGPR 2049
C+AC C HG+ +E +GG C + G
Sbjct: 332 AGTFLTKTECEACNC--HGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGIN 389
Query: 2050 CEVQLE-------LQPVCTPPCAP---------EAVC----------RAGNSCECSLGYE 2083
CE + + P PC P VC A SC C G+
Sbjct: 390 CETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFG 449
Query: 2084 GDGRVCTVADLCQDGHGGCSE--HANCSQVGT------MVTCTCLPDYEGDGWS-CRAR- 2133
G D C G+ G + NCS +G+ C C + EG S C++
Sbjct: 450 G-----VSCDRCARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGF 504
Query: 2134 -NPCTDGHRGGCSEHANCLSTGLNTRRCECHAGY 2166
N D + GC E C +G++ R C + Y
Sbjct: 505 FNLQEDNWK-GCDE---CFCSGVSNR---CQSSY 531
Score = 42.4 bits (98), Expect = 0.006
Identities = 53/197 (26%), Positives = 67/197 (34%), Gaps = 51/197 (25%)
Query: 1312 AKKIQVPDCCPGFFGTLCEPC----------PGG------LGGV----CSGHGQCQDRFL 1351
A I+ DC G+ G CE C PGG LG C+GH D
Sbjct: 1374 ADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPET 1433
Query: 1352 GSGECHCHEGFHGTACEVCELGRYG-----PNCTGVCDC---------AHGLCQEGLQGD 1397
+ +C G CE C LG YG PN C C + EGL
Sbjct: 1434 SICQ-NCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDY 1492
Query: 1398 GSCVCNVGWQGLRCDQ----KITSPQCPR------KCDPNANC-VQDSAGASTCACAAGY 1446
C G++G C++ SP P +CDP + V C C G
Sbjct: 1493 RCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGA 1552
Query: 1447 SGNGIFCSEVDPCAHGH 1463
+G + D C H H
Sbjct: 1553 TGR-----KCDGCKHWH 1564
Score = 40.8 bits (94), Expect = 0.017
Identities = 61/254 (24%), Positives = 87/254 (34%), Gaps = 56/254 (22%)
Query: 1336 LGGVCSGHGQCQ----DRFLGSGECHCHEGFHGTACEVCELG------RYGPNCTGV--- 1382
+GG+C +G + D C C G +C+ C G R G T
Sbjct: 283 VGGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECE 342
Query: 1383 -CDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQK---ITSPQCPRKCDPNANCVQDSAGAS 1438
C+C HG +E + NV + L + + I C NC Q++AG +
Sbjct: 343 ACNC-HGKAEECYYDE-----NVARRNLSLNIRGKYIGGGVC-------INCTQNTAGIN 389
Query: 1439 TCACAAG-YSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQE 1497
C G + G+ + PC H C P + +V C + + G
Sbjct: 390 CETCTDGFFRPKGVSPNYPRPCQPCH--CDPIGSLNEV------CVKDEKHARRG----- 436
Query: 1498 INSCLIHHGGCHIHAECIPTGPQQVSCS-CREGYSG-DGIRTCELLDPCSKNNGGCSPYA 1555
+ G CH TG VSC C GY+G + C SKN C
Sbjct: 437 -----LAPGSCH-----CKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKNEDPCFGPC 486
Query: 1556 TCKSTGDGQRTCTC 1569
CK +G C
Sbjct: 487 ICKENVEGGDCSRC 500
Score = 39.7 bits (91), Expect = 0.039
Identities = 40/179 (22%), Positives = 57/179 (31%), Gaps = 50/179 (27%)
Query: 654 CSEEQHKIVAGSCVDCQALNTST----------CPPNSVKLDIFPKECVYIHDPTGLNVL 703
C+ G C C+ + CPPN++ ++C T + +
Sbjct: 999 CAHGYFNFQEGGCTACECSHLGNNCDPKTGRCICPPNTIG-----EKCSKCAPNTWGHSI 1053
Query: 704 KKGCAS-----------YCNQTIMEQGCCKGFFGPDCTQCPGGFSN-------PCYGKG- 744
GC + CN + C F G CT+C G N C+ G
Sbjct: 1054 TTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGT 1113
Query: 745 ------------NCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQCQEDCGCVHGLC 791
+CSD G C C + +GI C C P K G + GC C
Sbjct: 1114 DATTCDSETKKCSCSD---QTGQCTCKVNVEGIHCDRC-RPGKFGLDAKNPLGCSSCYC 1168
Score = 39.7 bits (91), Expect = 0.039
Identities = 46/203 (22%), Positives = 62/203 (30%), Gaps = 76/203 (37%)
Query: 1994 QCLCRSGFAGTACELCAPGAF-----------GP---HCQACRCTVHGR-CDEGLGGSGS 2038
+C C G++G +CE C PG + GP C C+C H CD +
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN 1438
Query: 2039 C-------FCDE---GWTG--------------PRCEVQLELQPVCTPPCAPEAVCRAGN 2074
C FC+ G+ G P P C + C A
Sbjct: 1439 CQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTA-- 1496
Query: 2075 SCECSLGYEGDGRVCTVADLCQDGH-------GGCSEHANCSQVGTMVT--------CTC 2119
C GYEG + C G+ GG + C G++ CTC
Sbjct: 1497 ---CPRGYEGQ-----YCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTC 1548
Query: 2120 LPDYEG------------DGWSC 2130
P G +GW C
Sbjct: 1549 RPGATGRKCDGCKHWHAREGWEC 1571
Score = 39.3 bits (90), Expect = 0.051
Identities = 46/181 (25%), Positives = 63/181 (34%), Gaps = 50/181 (27%)
Query: 1355 ECHCHEGFHGTACEVCELGRY-----------GP--------NCTG---VCDCAHGL--- 1389
+C C G+ G +CE C G Y GP C G +CD +
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN 1438
Query: 1390 CQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNAN-----CVQDSAGASTC-ACA 1443
CQ GD C +G+ G+ QC ++N CV + C AC
Sbjct: 1439 CQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACP 1498
Query: 1444 AGYSGNGIFCSEVDPCAHGHGG-------------CSPHANC-TKVAPGQRTCTCQDGYM 1489
GY G +C + CA G+ G C P+ + P CTC+ G
Sbjct: 1499 RGYEGQ--YC---ERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGAT 1553
Query: 1490 G 1490
G
Sbjct: 1554 G 1554
Score = 38.1 bits (87), Expect = 0.11
Identities = 63/257 (24%), Positives = 84/257 (32%), Gaps = 72/257 (28%)
Query: 120 CNGHGTC--LDGMDRNGTCVCQENFRGSACQEC-----QDPNRFG-----PDCQSVCSCV 167
C GH LD C C+ N G +C +C Q P R G +C++ C+C
Sbjct: 289 CYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEA-CNC- 346
Query: 168 HGVC------NHGPRGDGSCLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAPSCRCLP 221
HG + R + S Y G VC + C QNT A C
Sbjct: 347 HGKAEECYYDENVARRNLSLNIRGKYIGG------GVC--INCTQNT---AGINCETCTD 395
Query: 222 GYTQ-QGSECRAPNPCWPSPC----SLLAQCSVSPK------GQAQCHCPENYHG----- 265
G+ + +G P PC P C SL C K CHC + G
Sbjct: 396 GFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDR 455
Query: 266 ----------------DGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPGLVSI 309
G+ +DPC G C +C G C+ G ++
Sbjct: 456 CARGYTGYPDCKACNCSGLGSKNEDPC---FGPC-----ICKENVEGGDCSRCKSGFFNL 507
Query: 310 NSNASAGC-FAFCSPFS 325
+ GC FCS S
Sbjct: 508 QEDNWKGCDECFCSGVS 524
Score = 37.7 bits (86), Expect = 0.15
Identities = 44/175 (25%), Positives = 58/175 (33%), Gaps = 53/175 (30%)
Query: 664 GSCVDCQAL-NTSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKGCASYCNQTIMEQGCCK 722
G+CV CQ ++S C P + N +C + C
Sbjct: 1415 GTCVPCQCNGHSSLCDPETSICQ---------------NCQHHTAGDFCER------CAL 1453
Query: 723 GFFG------PDCTQCP-------GGFSNPCYGKG-------NCSDGIQGNGACLCFPDY 762
G++G DC QC FS C +G C G +G C P Y
Sbjct: 1454 GYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRGYEGQYCERCAPGY 1513
Query: 763 KGIACHICSNPNKHGEQCQE-DCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCN 816
G +P G CQE +C L G C TC PG +GR C+
Sbjct: 1514 TG-------SPGNPGGSCQECECDPYGSLPVPCDPVTGFC---TCRPGATGRKCD 1558
Score = 35.8 bits (81), Expect = 0.56
Identities = 37/131 (28%), Positives = 54/131 (41%), Gaps = 20/131 (15%)
Query: 661 IVAGSCVDCQ----ALNTSTCP-----PNSVKLDIFPKECVYIH-DPTG-LNVLKKGCAS 709
I G C++C +N TC P V + +P+ C H DP G LN +
Sbjct: 373 IGGGVCINCTQNTAGINCETCTDGFFRPKGVSPN-YPRPCQPCHCDPIGSLNEVCVKDEK 431
Query: 710 YCNQTIMEQGC-CK-GFFGPDCTQCPGGFSN-PCYGKGNCSDGIQGN-----GACLCFPD 761
+ + + C CK GF G C +C G++ P NCS N G C+C +
Sbjct: 432 HARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKEN 491
Query: 762 YKGIACHICSN 772
+G C C +
Sbjct: 492 VEGGDCSRCKS 502
Score = 35.4 bits (80), Expect = 0.73
Identities = 39/159 (24%), Positives = 53/159 (33%), Gaps = 29/159 (18%)
Query: 1272 CVNCTRRF------RCTQGFQ------LQDTPRKSC-VYRSGFSFSRGCSYTCAKKIQVP 1318
C NC RC G+ D + +C + S +FS C +
Sbjct: 1436 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCT 1495
Query: 1319 DCCPGFFGTLCEPC-PGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGP 1377
C G+ G CE C PG G + G CQ EC C +G+ C+
Sbjct: 1496 ACPRGYEGQYCERCAPGYTGSPGNPGGSCQ-------ECECDP--YGSLPVPCD------ 1540
Query: 1378 NCTGVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKIT 1416
TG C C G G GW+ + C + T
Sbjct: 1541 PVTGFCTCRPGATGRKCDGCKHWHAREGWECVFCGDECT 1579
Score = 35.0 bits (79), Expect = 0.95
Identities = 30/116 (25%), Positives = 40/116 (34%), Gaps = 30/116 (25%)
Query: 100 CCPGYWG------SRCHECPGGAETPCNGHG-TCL-DGMDRNGTCVCQENFRGSACQECQ 151
C GY+G + C +C + N +C+ +G+D C + G C+ C
Sbjct: 1451 CALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRGYEGQYCERCA 1510
Query: 152 -----DPNRFGPDCQSVCSCVHGVCNHGPRGD---------GSCLCFAGYTGPHCD 193
P G CQ C C P G G C C G TG CD
Sbjct: 1511 PGYTGSPGNPGGSCQE-CEC-------DPYGSLPVPCDPVTGFCTCRPGATGRKCD 1558
Score = 34.7 bits (78), Expect = 1.2
Identities = 28/98 (28%), Positives = 36/98 (36%), Gaps = 6/98 (6%)
Query: 134 GTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVH-GVCNHGPRGDGSCLCFAGYTG--- 189
G+C C+ F G +C C PDC++ C+C G N P G C+C G
Sbjct: 440 GSCHCKTGFGGVSCDRCARGYTGYPDCKA-CNCSGLGSKNEDP-CFGPCICKENVEGGDC 497
Query: 190 PHCDQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQG 227
C QE +C S RC Y G
Sbjct: 498 SRCKSGFFNLQEDNWKGCDECFCSGVSNRCQSSYWTYG 535
Score = 32.3 bits (72), Expect = 6.2
Identities = 20/69 (28%), Positives = 29/69 (42%), Gaps = 14/69 (20%)
Query: 1955 WKPSCCP-GHYGSECQAC-PGGPSSPCSDRGVCMDGMSG------------SGQCLCRSG 2000
++ + CP G+ G C+ C PG SP + G C + +G C CR G
Sbjct: 1492 YRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPG 1551
Query: 2001 FAGTACELC 2009
G C+ C
Sbjct: 1552 ATGRKCDGC 1560
Score = 32.0 bits (71), Expect = 8.1
Identities = 28/101 (27%), Positives = 34/101 (33%), Gaps = 15/101 (14%)
Query: 1320 CCPGFFGTLCEPCPGGLGGV-------CSGHGQCQDRFLGSGECHCHEGFHGTACEVCEL 1372
C GF G C+ C G G CSG G ++ G C C E G C C+
Sbjct: 444 CKTGFGGVSCDRCARGYTGYPDCKACNCSGLGS-KNEDPCFGPCICKENVEGGDCSRCKS 502
Query: 1373 GRYG---PNCTGVCDC----AHGLCQEGLQGDGSCVCNVGW 1406
G + N G +C CQ G GW
Sbjct: 503 GFFNLQEDNWKGCDECFCSGVSNRCQSSYWTYGKIQDMSGW 543
Score = 32.0 bits (71), Expect = 8.1
Identities = 26/99 (26%), Positives = 34/99 (34%), Gaps = 25/99 (25%)
Query: 205 PQNTQCSAEAPSCRCLPGYTQQGSECRAPNPCWP--------------SPCSLLAQCSVS 250
P + +A C+C PGYT GS C + CWP PC
Sbjct: 712 PTDGSIAAAVEVCQCPPGYT--GSSCES---CWPRHRRVNGTIFGGICEPCQCFGHAESC 766
Query: 251 PKGQAQC-HCPENYHGDGMVCLPKDPCTDNLGGCPSNST 288
+C +C + H G C D C G P+ T
Sbjct: 767 DDVTGECLNCKD--HTGGPYC---DKCLPGFYGEPTKGT 800
>gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo
sapiens]
Length = 3122
Score = 93.6 bits (231), Expect = 2e-18
Identities = 128/493 (25%), Positives = 170/493 (34%), Gaps = 129/493 (26%)
Query: 1851 PFEGGLAYGIDQLLEPPGL-GARCDHFETRPLRLNTCSICGLEPPCPEGSQEQGSPEACW 1909
P +G +A ++ PPG G+ C+ R R+N G+ PC Q G E+C
Sbjct: 712 PTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPC----QCFGHAESCD 767
Query: 1910 RFYPKFWTSPPLHSLGLRSVWVHPSLWGRP-QGLGRGCHR-----NCVTTTWKPSC---- 1959
+ H+ G P +G P +G C N + + P+C
Sbjct: 768 DVTGECLNCKD-HTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDR 826
Query: 1960 --------CP-GHYGSECQAC----------PGGPSSPCSDRGVCMDGM---------SG 1991
CP G+ G C+ C PGG PC C D + S
Sbjct: 827 SLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQ----CNDNLDFSIPGSCDSL 882
Query: 1992 SGQCL-CRSGFAGTACELCAPGAFG-----PHCQACRCTVHGRCDEGL-GGSGSCFCDEG 2044
SG CL C+ G G CELCA G FG +CQ CRC G E +G C C
Sbjct: 883 SGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRAN 942
Query: 2045 WTGPRCE------VQLELQPVCTPPC------APEAVCRAGNSCECSLGYEGDGRVCTVA 2092
G RC+ L+ C PC + C C C G G+ C
Sbjct: 943 VQGQRCDKCKAGTFGLQSARGCV-PCNCNSFGSKSFDCEESGQCWCQPGV--TGKKC--- 996
Query: 2093 DLCQDGH-----GGCSEHANCSQVGTMV-----TCTCLPDYEGDGWSCRARNPCTDGH-- 2140
D C G+ GGC+ CS +G C C P+ G+ C P T GH
Sbjct: 997 DRCAHGYFNFQEGGCTA-CECSHLGNNCDPKTGRCICPPNTIGE--KCSKCAPNTWGHSI 1053
Query: 2141 RGGCSEHANCLSTG-------LNTRRCECHAGYVGDGLQCLE------------------ 2175
GC + NC + G +NT +C CH + G +C E
Sbjct: 1054 TTGC-KACNCSTVGSLDFQCNVNTGQCNCHPKF--SGAKCTECSRGHWNYPRCNLCDCFL 1110
Query: 2176 --------ESEPPVDRCLGQPPPCHSDAMCTDLHFQEKRAGVFHLQATSGPYGLN----F 2223
+SE C Q C +H R G F L A P G + F
Sbjct: 1111 PGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDA-KNPLGCSSCYCF 1169
Query: 2224 SEAEAACEAQGAV 2236
EA+G +
Sbjct: 1170 GTTTQCSEAKGLI 1182
Score = 68.9 bits (167), Expect = 6e-11
Identities = 76/277 (27%), Positives = 96/277 (34%), Gaps = 49/277 (17%)
Query: 100 CCPGYWGSRCHEC-----------PGGAETPCNGHGTCLDGMDRNGTCV-CQENFRGSAC 147
C PGY GS C C GG PC G D G C+ C+++ G C
Sbjct: 726 CPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLNCKDHTGGPYC 785
Query: 148 QECQDPNRFG-------PDCQSVCSCVHGVCN-------HGPRGDGSCL--CFAGYTGPH 191
+C P +G DCQ C+C + + H R G C GYTGP
Sbjct: 786 DKCL-PGFYGEPTKGTSEDCQP-CACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPR 843
Query: 192 CDQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQGSECRAPNPCWPSPCSLLAQCSVSP 251
C+ RC + P C P + P C S L C
Sbjct: 844 CE---------RCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLI-CKPGT 893
Query: 252 KGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPGLVSIN- 310
G+ C + Y GD + PC N GG S S +C + + GQ C CR +
Sbjct: 894 TGRYCELCADGYFGDAVDAKNCQPCRCNAGG--SFSEVC-HSQTGQ--CECRANVQGQRC 948
Query: 311 SNASAGCFAFCSPFSCDRSATCQVTADGKTSCVCRES 347
AG F S C C + G S C ES
Sbjct: 949 DKCKAGTFGLQSARGC---VPCNCNSFGSKSFDCEES 982
Score = 64.7 bits (156), Expect = 1e-09
Identities = 67/291 (23%), Positives = 92/291 (31%), Gaps = 52/291 (17%)
Query: 53 QTCPSGWLRELPD-QITQDCRYEVQLGGSMVSMSGCRRKCRKQVVQKACCPGYWGSRCHE 111
+ C G+ + D + Q CR GGS + C Q Q C G RC +
Sbjct: 899 ELCADGYFGDAVDAKNCQPCRCNA--GGSFSEV------CHSQTGQCECRANVQGQRCDK 950
Query: 112 CPGGA----------ETPCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPN-RFGPDC 160
C G CN G+ + +G C CQ G C C F
Sbjct: 951 CKAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGG 1010
Query: 161 QSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQELP---------VCQELRCPQ----N 207
+ C C H N P+ G C+C G C + P C+ C +
Sbjct: 1011 CTACECSHLGNNCDPK-TGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLD 1069
Query: 208 TQCSAEAPSCRCLPGYTQQGSEC-RAPNPCWPSPCSLLAQCSVSPKGQAQCHCPENYHGD 266
QC+ C C P ++ G++C W P L C + C
Sbjct: 1070 FQCNVNTGQCNCHPKFS--GAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETK---- 1123
Query: 267 GMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPGLVSINSNASAGC 317
K C+D G C C G CRPG +++ GC
Sbjct: 1124 ------KCSCSDQTGQC-----TCKVNVEGIHCDRCRPGKFGLDAKNPLGC 1163
Score = 63.5 bits (153), Expect = 3e-09
Identities = 79/289 (27%), Positives = 101/289 (34%), Gaps = 60/289 (20%)
Query: 1312 AKKIQVPDCCPGFFGTLCEPC------PGG--LGGVCS-----GHGQ-CQDRFLGSGEC- 1356
A ++V C PG+ G+ CE C G GG+C GH + C D +GEC
Sbjct: 718 AAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDD---VTGECL 774
Query: 1357 HCHEGFHGTACEVCELGRYGPNCTGVC-DCAHGLCQEGLQGDG-SCVCNVGWQ-GLRCD- 1412
+C + G C+ C G YG G DC C + + S C++ GL CD
Sbjct: 775 NCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDG 834
Query: 1413 --QKITSPQCPRKCDPNANCVQDSAGASTCACAAGYSGN-GIFCSEVDPCAHGH------ 1463
T P+C R CA GY G + PC
Sbjct: 835 CPVGYTGPRCER-------------------CAEGYFGQPSVPGGSCQPCQCNDNLDFSI 875
Query: 1464 -GGC-SPHANCTKVAPGQ--RTC-TCQDGYMGDGELCQEINSCLIHHGGCHIHAECIPTG 1518
G C S +C PG R C C DGY GD + C + GG TG
Sbjct: 876 PGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTG 935
Query: 1519 PQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKSTGDGQRTC 1567
C CR G C+ ++ GC P C S G C
Sbjct: 936 ----QCECRANVQGQRCDKCKAGTFGLQSARGCVP-CNCNSFGSKSFDC 979
Score = 62.0 bits (149), Expect = 7e-09
Identities = 92/368 (25%), Positives = 124/368 (33%), Gaps = 90/368 (24%)
Query: 1264 HAEALRE---KCVNCTRRF------RCTQGFQLQDTPRKS-----CVYRSGF---SFSRG 1306
HAE+ + +C+NC +C GF + T S C +FS
Sbjct: 762 HAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPT 821
Query: 1307 CSYTCAKKIQVPDCCPGFFGTLCEPCPGGLGGVCSGHG------QCQDR--FLGSGECH- 1357
C + + C G+ G CE C G G S G QC D F G C
Sbjct: 822 CHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDS 881
Query: 1358 -------CHEGFHGTACEVCELGRYG-----PNCTGV-CDCAHGLCQEGLQGDGSCVCNV 1404
C G G CE+C G +G NC C+ + G C C
Sbjct: 882 LSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRA 941
Query: 1405 GWQGLRCDQKITSP---QCPRKCDPNANCVQ------DSAGASTCACAAGYSGNGIFCSE 1455
QG RCD+ Q R C P NC D + C C G +G +
Sbjct: 942 NVQGQRCDKCKAGTFGLQSARGCVP-CNCNSFGSKSFDCEESGQCWCQPGVTG-----KK 995
Query: 1456 VDPCAHGH-----GGCSPHANCTKVA----PGQRTCTCQDGYMGDGELCQEINSCLIHHG 1506
D CAHG+ GGC+ C+ + P C C +G ++ + C +
Sbjct: 996 CDRCAHGYFNFQEGGCTA-CECSHLGNNCDPKTGRCICPPNTIG-----EKCSKCAPNTW 1049
Query: 1507 GCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLD-PCSKNNGGCSPYATCKSTGDGQR 1565
G I TG + +CS T LD C+ N G C+ C G +
Sbjct: 1050 G-----HSITTGCKACNCS-----------TVGSLDFQCNVNTGQCN----CHPKFSGAK 1089
Query: 1566 TCTCDTAH 1573
C H
Sbjct: 1090 CTECSRGH 1097
Score = 61.2 bits (147), Expect = 1e-08
Identities = 69/260 (26%), Positives = 82/260 (31%), Gaps = 59/260 (22%)
Query: 756 CLCFPDYKGIACHICSNPNKHG---------EQCQ-----EDCGCVHGLCDNRPGSGGVC 801
C C P Y G +C C ++ E CQ E C V G C N G
Sbjct: 724 CQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLNCKDHTGGP 783
Query: 802 QQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGDGFSCTP 861
C PGF G + DC P C C + FS
Sbjct: 784 YCDKCLPGFYGEPTKGTSEDCQP---------------------CACPLNIPSNNFS--- 819
Query: 862 SNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGRV-------CVAIDECELDMRG 914
P H DR C G G C +G+ G V C D + + G
Sbjct: 820 --PTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPG 877
Query: 915 GCHT-DALCSYVGPGQSRCTCKL---GFAGDGYQCSPIDPCRAGNGG-----CH---GLA 962
C + C PG + C+L G+ GD PCR GG CH G
Sbjct: 878 SCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQC 937
Query: 963 TCRAVGGGQRVCTCPPGFGG 982
CRA GQR C G G
Sbjct: 938 ECRANVQGQRCDKCKAGTFG 957
Score = 60.5 bits (145), Expect = 2e-08
Identities = 78/304 (25%), Positives = 99/304 (32%), Gaps = 90/304 (29%)
Query: 719 GCCKGFFGPDCTQC----------PGGFSNPCYGKGNCSDGIQG-----NGACL-CFPDY 762
GC G+ GP C +C PGG PC N I G +G+CL C P
Sbjct: 834 GCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGT 893
Query: 763 KGIACHICSN----PNKHGEQCQEDCGCVHG-----LCDNRPGSGGVCQQGTCAPGFSGR 813
G C +C++ + CQ C C G +C ++ G Q C G+
Sbjct: 894 TGRYCELCADGYFGDAVDAKNCQ-PCRCNAGGSFSEVCHSQTG------QCECRANVQGQ 946
Query: 814 FCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGC 873
C++ G GL S G C C + F F C S C
Sbjct: 947 RCDKC--KAGTFGLQ----------SARGCVPCNC-NSFGSKSFDCEESGQC-------- 985
Query: 874 SENAECVPGSLGTHHCTCHKGWSGDGRVCVAIDECELDMRGGCHTDALCSYVG----PGQ 929
C PG G C G+ GGC T CS++G P
Sbjct: 986 ----WCQPGVTGKKCDRCAHGYFN-------------FQEGGC-TACECSHLGNNCDPKT 1027
Query: 930 SRCTCKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRA-----------VGGGQRVCTCPP 978
RC C G+ +CS P G+ G C V GQ C C P
Sbjct: 1028 GRCICPPNTIGE--KCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQ--CNCHP 1083
Query: 979 GFGG 982
F G
Sbjct: 1084 KFSG 1087
Score = 54.7 bits (130), Expect = 1e-06
Identities = 36/112 (32%), Positives = 50/112 (44%), Gaps = 13/112 (11%)
Query: 1949 NCVTTT---WKPSCCPGHYGSECQACPGGPSSPCSDRGVCMDGMSGS------GQCLCRS 1999
NC T T ++P +Y CQ C P ++ VC+ + G C C++
Sbjct: 389 NCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNE--VCVKDEKHARRGLAPGSCHCKT 446
Query: 2000 GFAGTACELCAPGAFG-PHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRC 2050
GF G +C+ CA G G P C+AC C+ G +E G C C E G C
Sbjct: 447 GFGGVSCDRCARGYTGYPDCKACNCSGLGSKNED-PCFGPCICKENVEGGDC 497
Score = 50.4 bits (119), Expect = 2e-05
Identities = 36/111 (32%), Positives = 46/111 (41%), Gaps = 21/111 (18%)
Query: 1959 CCPGHYG------SECQ--ACPGGPSSPCSDRGVCMDGMSGSGQCLCRSGFAGTACELCA 2010
C G+YG ++CQ ACP SS +G+ C G+ G CE CA
Sbjct: 1451 CALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRGYEGQYCERCA 1510
Query: 2011 PGAFGP------HCQACRCTVHGR----CDEGLGGSGSCFCDEGWTGPRCE 2051
PG G CQ C C +G CD +G C C G TG +C+
Sbjct: 1511 PGYTGSPGNPGGSCQECECDPYGSLPVPCDP---VTGFCTCRPGATGRKCD 1558
Score = 49.7 bits (117), Expect = 4e-05
Identities = 57/241 (23%), Positives = 83/241 (34%), Gaps = 51/241 (21%)
Query: 1250 SGVLTVGSSR-CLHSHAEALREKCVNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRG-- 1306
+G + S+R C+ + + K +C +C + C + F+F G
Sbjct: 953 AGTFGLQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAH-GYFNFQEGGC 1011
Query: 1307 ----CSY---TCAKKIQVPDCCPGFFGTLCEPCPGGLGG--VCSGHGQCQDRFLGS---- 1353
CS+ C K C P G C C G + +G C +GS
Sbjct: 1012 TACECSHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQ 1071
Query: 1354 -----GECHCHEGFHGTACEVCELGRYG-PNCTGVCDC-----AHGLCQEGLQ------G 1396
G+C+CH F G C C G + P C +CDC C +
Sbjct: 1072 CNVNTGQCNCHPKFSGAKCTECSRGHWNYPRC-NLCDCFLPGTDATTCDSETKKCSCSDQ 1130
Query: 1397 DGSCVCNVGWQGLRCDQKITSPQCPRKCDPN--ANCVQDSAGASTCACAAGYSGNGIFCS 1454
G C C V +G+ CD +C P ++ G S+C C G CS
Sbjct: 1131 TGQCTCKVNVEGIHCD----------RCRPGKFGLDAKNPLGCSSCYC----FGTTTQCS 1176
Query: 1455 E 1455
E
Sbjct: 1177 E 1177
Score = 49.3 bits (116), Expect = 5e-05
Identities = 34/113 (30%), Positives = 45/113 (39%), Gaps = 15/113 (13%)
Query: 1315 IQVPDCCPGFFGTL---------CEPCP----GGLGGVCSGHGQCQDRFLGSGECHCHEG 1361
I C GFF C+PC G L VC + R L G CHC G
Sbjct: 388 INCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTG 447
Query: 1362 FHGTACEVCELGRYG-PNCTGVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQ 1413
F G +C+ C G G P+C C+C+ + G C+C +G C +
Sbjct: 448 FGGVSCDRCARGYTGYPDCK-ACNCSGLGSKNEDPCFGPCICKENVEGGDCSR 499
Score = 48.1 bits (113), Expect = 1e-04
Identities = 63/225 (28%), Positives = 79/225 (35%), Gaps = 63/225 (28%)
Query: 95 VVQKACCP-GYWGSRCHEC-PG--------GAETPCNGHGTCLDGMDRNGTCVCQENFRG 144
+++K CP GY G C C PG G TP GTC+ CQ N
Sbjct: 1376 LIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVP---------CQCNGHS 1426
Query: 145 SACQECQDPNRFGPDCQSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQELPV-CQELR 203
S C DP S+C C H GD C GY G + LP CQ+
Sbjct: 1427 SLC----DPET------SICQN----CQHHTAGDFCERCALGYYG--IVKGLPNDCQQCA 1470
Query: 204 CPQNTQCSAEAPSCRC--LPGYTQQGSECRAPNPCWPSPCSLLAQCSVSPKGQAQCHCPE 261
CP + + +PSC L Y +C+ P+G +C
Sbjct: 1471 CPLISSSNNFSPSCVAEGLDDY----------------------RCTACPRGYEGQYCER 1508
Query: 262 NYHG-DGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPG 305
G G P C + C +L V P FCTCRPG
Sbjct: 1509 CAPGYTGSPGNPGGSCQEC--ECDPYGSLPVPCDPVTGFCTCRPG 1551
Score = 47.4 bits (111), Expect = 2e-04
Identities = 29/94 (30%), Positives = 38/94 (40%), Gaps = 18/94 (19%)
Query: 100 CCPGYWG-SRCHEC----PGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPN 154
C G+W RC+ C PG T C+ D+ G C C+ N G C C+ P
Sbjct: 1093 CSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCR-PG 1151
Query: 155 RFGPDCQSVCSCVHGVCNHGPRGDGSCLCFAGYT 188
+FG D ++ P G SC CF T
Sbjct: 1152 KFGLDAKN------------PLGCSSCYCFGTTT 1173
Score = 44.7 bits (104), Expect = 0.001
Identities = 63/274 (22%), Positives = 89/274 (32%), Gaps = 98/274 (35%)
Query: 1960 CPGHYGSECQACPGGPSSPCSDRGVCMDGMSGSGQCLCRSGFAGTACELCAPG------- 2012
C GH +ACP +D + +C C G +C+ C PG
Sbjct: 289 CYGH----ARACP-------------LDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWR 331
Query: 2013 ----AFGPHCQACRCTVHGRCDE-------------------GLGGSGSCFCDEGWTGPR 2049
C+AC C HG+ +E +GG C + G
Sbjct: 332 AGTFLTKTECEACNC--HGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGIN 389
Query: 2050 CEVQLE-------LQPVCTPPCAP---------EAVC----------RAGNSCECSLGYE 2083
CE + + P PC P VC A SC C G+
Sbjct: 390 CETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFG 449
Query: 2084 GDGRVCTVADLCQDGHGGCSE--HANCSQVGT------MVTCTCLPDYEGDGWS-CRAR- 2133
G D C G+ G + NCS +G+ C C + EG S C++
Sbjct: 450 G-----VSCDRCARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGF 504
Query: 2134 -NPCTDGHRGGCSEHANCLSTGLNTRRCECHAGY 2166
N D + GC E C +G++ R C + Y
Sbjct: 505 FNLQEDNWK-GCDE---CFCSGVSNR---CQSSY 531
Score = 42.4 bits (98), Expect = 0.006
Identities = 53/197 (26%), Positives = 67/197 (34%), Gaps = 51/197 (25%)
Query: 1312 AKKIQVPDCCPGFFGTLCEPC----------PGG------LGGV----CSGHGQCQDRFL 1351
A I+ DC G+ G CE C PGG LG C+GH D
Sbjct: 1374 ADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPET 1433
Query: 1352 GSGECHCHEGFHGTACEVCELGRYG-----PNCTGVCDC---------AHGLCQEGLQGD 1397
+ +C G CE C LG YG PN C C + EGL
Sbjct: 1434 SICQ-NCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDY 1492
Query: 1398 GSCVCNVGWQGLRCDQ----KITSPQCPR------KCDPNANC-VQDSAGASTCACAAGY 1446
C G++G C++ SP P +CDP + V C C G
Sbjct: 1493 RCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGA 1552
Query: 1447 SGNGIFCSEVDPCAHGH 1463
+G + D C H H
Sbjct: 1553 TGR-----KCDGCKHWH 1564
Score = 40.8 bits (94), Expect = 0.017
Identities = 61/254 (24%), Positives = 87/254 (34%), Gaps = 56/254 (22%)
Query: 1336 LGGVCSGHGQCQ----DRFLGSGECHCHEGFHGTACEVCELG------RYGPNCTGV--- 1382
+GG+C +G + D C C G +C+ C G R G T
Sbjct: 283 VGGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECE 342
Query: 1383 -CDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQK---ITSPQCPRKCDPNANCVQDSAGAS 1438
C+C HG +E + NV + L + + I C NC Q++AG +
Sbjct: 343 ACNC-HGKAEECYYDE-----NVARRNLSLNIRGKYIGGGVC-------INCTQNTAGIN 389
Query: 1439 TCACAAG-YSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQE 1497
C G + G+ + PC H C P + +V C + + G
Sbjct: 390 CETCTDGFFRPKGVSPNYPRPCQPCH--CDPIGSLNEV------CVKDEKHARRG----- 436
Query: 1498 INSCLIHHGGCHIHAECIPTGPQQVSCS-CREGYSG-DGIRTCELLDPCSKNNGGCSPYA 1555
+ G CH TG VSC C GY+G + C SKN C
Sbjct: 437 -----LAPGSCH-----CKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKNEDPCFGPC 486
Query: 1556 TCKSTGDGQRTCTC 1569
CK +G C
Sbjct: 487 ICKENVEGGDCSRC 500
Score = 39.7 bits (91), Expect = 0.039
Identities = 40/179 (22%), Positives = 57/179 (31%), Gaps = 50/179 (27%)
Query: 654 CSEEQHKIVAGSCVDCQALNTST----------CPPNSVKLDIFPKECVYIHDPTGLNVL 703
C+ G C C+ + CPPN++ ++C T + +
Sbjct: 999 CAHGYFNFQEGGCTACECSHLGNNCDPKTGRCICPPNTIG-----EKCSKCAPNTWGHSI 1053
Query: 704 KKGCAS-----------YCNQTIMEQGCCKGFFGPDCTQCPGGFSN-------PCYGKG- 744
GC + CN + C F G CT+C G N C+ G
Sbjct: 1054 TTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGT 1113
Query: 745 ------------NCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQCQEDCGCVHGLC 791
+CSD G C C + +GI C C P K G + GC C
Sbjct: 1114 DATTCDSETKKCSCSD---QTGQCTCKVNVEGIHCDRC-RPGKFGLDAKNPLGCSSCYC 1168
Score = 39.7 bits (91), Expect = 0.039
Identities = 46/203 (22%), Positives = 62/203 (30%), Gaps = 76/203 (37%)
Query: 1994 QCLCRSGFAGTACELCAPGAF-----------GP---HCQACRCTVHGR-CDEGLGGSGS 2038
+C C G++G +CE C PG + GP C C+C H CD +
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN 1438
Query: 2039 C-------FCDE---GWTG--------------PRCEVQLELQPVCTPPCAPEAVCRAGN 2074
C FC+ G+ G P P C + C A
Sbjct: 1439 CQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTA-- 1496
Query: 2075 SCECSLGYEGDGRVCTVADLCQDGH-------GGCSEHANCSQVGTMVT--------CTC 2119
C GYEG + C G+ GG + C G++ CTC
Sbjct: 1497 ---CPRGYEGQ-----YCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTC 1548
Query: 2120 LPDYEG------------DGWSC 2130
P G +GW C
Sbjct: 1549 RPGATGRKCDGCKHWHAREGWEC 1571
Score = 39.3 bits (90), Expect = 0.051
Identities = 46/181 (25%), Positives = 63/181 (34%), Gaps = 50/181 (27%)
Query: 1355 ECHCHEGFHGTACEVCELGRY-----------GP--------NCTG---VCDCAHGL--- 1389
+C C G+ G +CE C G Y GP C G +CD +
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN 1438
Query: 1390 CQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNAN-----CVQDSAGASTC-ACA 1443
CQ GD C +G+ G+ QC ++N CV + C AC
Sbjct: 1439 CQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACP 1498
Query: 1444 AGYSGNGIFCSEVDPCAHGHGG-------------CSPHANC-TKVAPGQRTCTCQDGYM 1489
GY G +C + CA G+ G C P+ + P CTC+ G
Sbjct: 1499 RGYEGQ--YC---ERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGAT 1553
Query: 1490 G 1490
G
Sbjct: 1554 G 1554
Score = 38.1 bits (87), Expect = 0.11
Identities = 63/257 (24%), Positives = 84/257 (32%), Gaps = 72/257 (28%)
Query: 120 CNGHGTC--LDGMDRNGTCVCQENFRGSACQEC-----QDPNRFG-----PDCQSVCSCV 167
C GH LD C C+ N G +C +C Q P R G +C++ C+C
Sbjct: 289 CYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEA-CNC- 346
Query: 168 HGVC------NHGPRGDGSCLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAPSCRCLP 221
HG + R + S Y G VC + C QNT A C
Sbjct: 347 HGKAEECYYDENVARRNLSLNIRGKYIGG------GVC--INCTQNT---AGINCETCTD 395
Query: 222 GYTQ-QGSECRAPNPCWPSPC----SLLAQCSVSPK------GQAQCHCPENYHG----- 265
G+ + +G P PC P C SL C K CHC + G
Sbjct: 396 GFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDR 455
Query: 266 ----------------DGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPGLVSI 309
G+ +DPC G C +C G C+ G ++
Sbjct: 456 CARGYTGYPDCKACNCSGLGSKNEDPC---FGPC-----ICKENVEGGDCSRCKSGFFNL 507
Query: 310 NSNASAGC-FAFCSPFS 325
+ GC FCS S
Sbjct: 508 QEDNWKGCDECFCSGVS 524
Score = 37.7 bits (86), Expect = 0.15
Identities = 44/175 (25%), Positives = 58/175 (33%), Gaps = 53/175 (30%)
Query: 664 GSCVDCQAL-NTSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKGCASYCNQTIMEQGCCK 722
G+CV CQ ++S C P + N +C + C
Sbjct: 1415 GTCVPCQCNGHSSLCDPETSICQ---------------NCQHHTAGDFCER------CAL 1453
Query: 723 GFFG------PDCTQCP-------GGFSNPCYGKG-------NCSDGIQGNGACLCFPDY 762
G++G DC QC FS C +G C G +G C P Y
Sbjct: 1454 GYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRGYEGQYCERCAPGY 1513
Query: 763 KGIACHICSNPNKHGEQCQE-DCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCN 816
G +P G CQE +C L G C TC PG +GR C+
Sbjct: 1514 TG-------SPGNPGGSCQECECDPYGSLPVPCDPVTGFC---TCRPGATGRKCD 1558
Score = 35.8 bits (81), Expect = 0.56
Identities = 37/131 (28%), Positives = 54/131 (41%), Gaps = 20/131 (15%)
Query: 661 IVAGSCVDCQ----ALNTSTCP-----PNSVKLDIFPKECVYIH-DPTG-LNVLKKGCAS 709
I G C++C +N TC P V + +P+ C H DP G LN +
Sbjct: 373 IGGGVCINCTQNTAGINCETCTDGFFRPKGVSPN-YPRPCQPCHCDPIGSLNEVCVKDEK 431
Query: 710 YCNQTIMEQGC-CK-GFFGPDCTQCPGGFSN-PCYGKGNCSDGIQGN-----GACLCFPD 761
+ + + C CK GF G C +C G++ P NCS N G C+C +
Sbjct: 432 HARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKEN 491
Query: 762 YKGIACHICSN 772
+G C C +
Sbjct: 492 VEGGDCSRCKS 502
Score = 35.4 bits (80), Expect = 0.73
Identities = 39/159 (24%), Positives = 53/159 (33%), Gaps = 29/159 (18%)
Query: 1272 CVNCTRRF------RCTQGFQ------LQDTPRKSC-VYRSGFSFSRGCSYTCAKKIQVP 1318
C NC RC G+ D + +C + S +FS C +
Sbjct: 1436 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCT 1495
Query: 1319 DCCPGFFGTLCEPC-PGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGP 1377
C G+ G CE C PG G + G CQ EC C +G+ C+
Sbjct: 1496 ACPRGYEGQYCERCAPGYTGSPGNPGGSCQ-------ECECDP--YGSLPVPCD------ 1540
Query: 1378 NCTGVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKIT 1416
TG C C G G GW+ + C + T
Sbjct: 1541 PVTGFCTCRPGATGRKCDGCKHWHAREGWECVFCGDECT 1579
Score = 35.0 bits (79), Expect = 0.95
Identities = 30/116 (25%), Positives = 40/116 (34%), Gaps = 30/116 (25%)
Query: 100 CCPGYWG------SRCHECPGGAETPCNGHG-TCL-DGMDRNGTCVCQENFRGSACQECQ 151
C GY+G + C +C + N +C+ +G+D C + G C+ C
Sbjct: 1451 CALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRGYEGQYCERCA 1510
Query: 152 -----DPNRFGPDCQSVCSCVHGVCNHGPRGD---------GSCLCFAGYTGPHCD 193
P G CQ C C P G G C C G TG CD
Sbjct: 1511 PGYTGSPGNPGGSCQE-CEC-------DPYGSLPVPCDPVTGFCTCRPGATGRKCD 1558
Score = 34.7 bits (78), Expect = 1.2
Identities = 28/98 (28%), Positives = 36/98 (36%), Gaps = 6/98 (6%)
Query: 134 GTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVH-GVCNHGPRGDGSCLCFAGYTG--- 189
G+C C+ F G +C C PDC++ C+C G N P G C+C G
Sbjct: 440 GSCHCKTGFGGVSCDRCARGYTGYPDCKA-CNCSGLGSKNEDP-CFGPCICKENVEGGDC 497
Query: 190 PHCDQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQG 227
C QE +C S RC Y G
Sbjct: 498 SRCKSGFFNLQEDNWKGCDECFCSGVSNRCQSSYWTYG 535
Score = 32.3 bits (72), Expect = 6.2
Identities = 20/69 (28%), Positives = 29/69 (42%), Gaps = 14/69 (20%)
Query: 1955 WKPSCCP-GHYGSECQAC-PGGPSSPCSDRGVCMDGMSG------------SGQCLCRSG 2000
++ + CP G+ G C+ C PG SP + G C + +G C CR G
Sbjct: 1492 YRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPG 1551
Query: 2001 FAGTACELC 2009
G C+ C
Sbjct: 1552 ATGRKCDGC 1560
Score = 32.0 bits (71), Expect = 8.1
Identities = 28/101 (27%), Positives = 34/101 (33%), Gaps = 15/101 (14%)
Query: 1320 CCPGFFGTLCEPCPGGLGGV-------CSGHGQCQDRFLGSGECHCHEGFHGTACEVCEL 1372
C GF G C+ C G G CSG G ++ G C C E G C C+
Sbjct: 444 CKTGFGGVSCDRCARGYTGYPDCKACNCSGLGS-KNEDPCFGPCICKENVEGGDCSRCKS 502
Query: 1373 GRYG---PNCTGVCDC----AHGLCQEGLQGDGSCVCNVGW 1406
G + N G +C CQ G GW
Sbjct: 503 GFFNLQEDNWKGCDECFCSGVSNRCQSSYWTYGKIQDMSGW 543
Score = 32.0 bits (71), Expect = 8.1
Identities = 26/99 (26%), Positives = 34/99 (34%), Gaps = 25/99 (25%)
Query: 205 PQNTQCSAEAPSCRCLPGYTQQGSECRAPNPCWP--------------SPCSLLAQCSVS 250
P + +A C+C PGYT GS C + CWP PC
Sbjct: 712 PTDGSIAAAVEVCQCPPGYT--GSSCES---CWPRHRRVNGTIFGGICEPCQCFGHAESC 766
Query: 251 PKGQAQC-HCPENYHGDGMVCLPKDPCTDNLGGCPSNST 288
+C +C + H G C D C G P+ T
Sbjct: 767 DDVTGECLNCKD--HTGGPYC---DKCLPGFYGEPTKGT 800
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.139 0.466
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 123,303,364
Number of Sequences: 37866
Number of extensions: 6975475
Number of successful extensions: 31951
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 173
Number of HSP's successfully gapped in prelim test: 324
Number of HSP's that attempted gapping in prelim test: 15317
Number of HSP's gapped (non-prelim): 7235
length of query: 2570
length of database: 18,247,518
effective HSP length: 119
effective length of query: 2451
effective length of database: 13,741,464
effective search space: 33680328264
effective search space used: 33680328264
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.