Guide to the Human Genome
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Search of human proteins with 5902112

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5902112 SRY (sex determining region Y)-box 30 isoform b
[Homo sapiens]
         (501 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo...  1003   0.0  
gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Hom...   929   0.0  
gi|169168396 PREDICTED: hypothetical protein [Homo sapiens]           114   3e-25
gi|239748690 PREDICTED: hypothetical protein [Homo sapiens]           114   3e-25
gi|239742713 PREDICTED: hypothetical protein [Homo sapiens]           114   3e-25
gi|13899269 SRY-box 7 [Homo sapiens]                                   92   1e-18
gi|4759162 SRY-box 14 [Homo sapiens]                                   92   1e-18
gi|5902108 SRY-box 21 [Homo sapiens]                                   91   3e-18
gi|4507225 sex determining region Y [Homo sapiens]                     89   9e-18
gi|5902106 SRY-box 15 [Homo sapiens]                                   88   2e-17
gi|28195386 sex-determining region Y-box 2 [Homo sapiens]              87   3e-17
gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens]        87   4e-17
gi|4557853 transcription factor SOX9 [Homo sapiens]                    86   6e-17
gi|4507161 SRY-box 11 [Homo sapiens]                                   86   6e-17
gi|41406089 SRY-box 13 [Homo sapiens]                                  85   1e-16
gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens]         85   2e-16
gi|30179903 SRY (sex determining region Y)-box 8 [Homo sapiens]        84   2e-16
gi|30061556 SRY (sex determining region Y)-box 3 [Homo sapiens]        84   4e-16
gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Hom...    83   5e-16
gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Hom...    83   5e-16
gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo...    83   5e-16
gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo...    83   5e-16
gi|5902104 SRY (sex determining region Y)-box 10 [Homo sapiens]        82   9e-16
gi|21264339 SRY (sex determining region Y)-box 12 [Homo sapiens]       82   9e-16
gi|11967991 SRY-box 17 [Homo sapiens]                                  82   1e-15
gi|30061558 SRY (sex determining region Y)-box 5 isoform c [Homo...    82   1e-15
gi|23308715 SRY (sex determining region Y)-box 5 isoform b [Homo...    82   1e-15
gi|23308713 SRY (sex determining region Y)-box 5 isoform a [Homo...    82   1e-15
gi|8924248 SRY-box 18 [Homo sapiens]                                   79   1e-14
gi|226371764 transcription factor 7-like 2 isoform 1 [Homo sapiens]    71   2e-12

>gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo
           sapiens]
          Length = 501

 Score = 1003 bits (2594), Expect = 0.0
 Identities = 501/501 (100%), Positives = 501/501 (100%)

Query: 1   MERARPEPPPQPRPLRPAPPPLPVEGTSFWAAAMEPPPSSPTLSAAASATLASSCGEAVA 60
           MERARPEPPPQPRPLRPAPPPLPVEGTSFWAAAMEPPPSSPTLSAAASATLASSCGEAVA
Sbjct: 1   MERARPEPPPQPRPLRPAPPPLPVEGTSFWAAAMEPPPSSPTLSAAASATLASSCGEAVA 60

Query: 61  SGLQPAVRRLLQVKPEQVLLLPQPQAQNEEAAASSAQARLLQFRPDLRLLQPPTASDGAT 120
           SGLQPAVRRLLQVKPEQVLLLPQPQAQNEEAAASSAQARLLQFRPDLRLLQPPTASDGAT
Sbjct: 61  SGLQPAVRRLLQVKPEQVLLLPQPQAQNEEAAASSAQARLLQFRPDLRLLQPPTASDGAT 120

Query: 121 SRPELHPVQPLALHVKAKKQKLGPSLDQSVGPRGAVETGPRASRVVKLEGPGPALGYFRG 180
           SRPELHPVQPLALHVKAKKQKLGPSLDQSVGPRGAVETGPRASRVVKLEGPGPALGYFRG
Sbjct: 121 SRPELHPVQPLALHVKAKKQKLGPSLDQSVGPRGAVETGPRASRVVKLEGPGPALGYFRG 180

Query: 181 DEKGKLEAEEVMRDSMQGGAGKSPAAIREGVIKTEEPERLLEDCRLGAEPASNGLVHGSA 240
           DEKGKLEAEEVMRDSMQGGAGKSPAAIREGVIKTEEPERLLEDCRLGAEPASNGLVHGSA
Sbjct: 181 DEKGKLEAEEVMRDSMQGGAGKSPAAIREGVIKTEEPERLLEDCRLGAEPASNGLVHGSA 240

Query: 241 EVILAPTSGAFGPHQQDLRIPLTLHTVPPGARIQFQGAPPSELIRLTKVPLTPVPTKMQS 300
           EVILAPTSGAFGPHQQDLRIPLTLHTVPPGARIQFQGAPPSELIRLTKVPLTPVPTKMQS
Sbjct: 241 EVILAPTSGAFGPHQQDLRIPLTLHTVPPGARIQFQGAPPSELIRLTKVPLTPVPTKMQS 300

Query: 301 LLEPSVKIETKDVPLTVLPSDAGIPDTPFSKDRNGHVKRPMNAFMVWARIHRPALAKANP 360
           LLEPSVKIETKDVPLTVLPSDAGIPDTPFSKDRNGHVKRPMNAFMVWARIHRPALAKANP
Sbjct: 301 LLEPSVKIETKDVPLTVLPSDAGIPDTPFSKDRNGHVKRPMNAFMVWARIHRPALAKANP 360

Query: 361 AANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKEKHREEFPGWVYQPRPGKRKRFPLSV 420
           AANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKEKHREEFPGWVYQPRPGKRKRFPLSV
Sbjct: 361 AANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKEKHREEFPGWVYQPRPGKRKRFPLSV 420

Query: 421 SNVFSGTTQNIISTNPTTVYPYRSPTYSVVIPSLQNPITHPVVHALTVGLPLAMEIFRVQ 480
           SNVFSGTTQNIISTNPTTVYPYRSPTYSVVIPSLQNPITHPVVHALTVGLPLAMEIFRVQ
Sbjct: 421 SNVFSGTTQNIISTNPTTVYPYRSPTYSVVIPSLQNPITHPVVHALTVGLPLAMEIFRVQ 480

Query: 481 CQNALVIMKTGTQNMRVSFQL 501
           CQNALVIMKTGTQNMRVSFQL
Sbjct: 481 CQNALVIMKTGTQNMRVSFQL 501


>gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Homo
           sapiens]
          Length = 753

 Score =  929 bits (2400), Expect = 0.0
 Identities = 462/462 (100%), Positives = 462/462 (100%)

Query: 1   MERARPEPPPQPRPLRPAPPPLPVEGTSFWAAAMEPPPSSPTLSAAASATLASSCGEAVA 60
           MERARPEPPPQPRPLRPAPPPLPVEGTSFWAAAMEPPPSSPTLSAAASATLASSCGEAVA
Sbjct: 1   MERARPEPPPQPRPLRPAPPPLPVEGTSFWAAAMEPPPSSPTLSAAASATLASSCGEAVA 60

Query: 61  SGLQPAVRRLLQVKPEQVLLLPQPQAQNEEAAASSAQARLLQFRPDLRLLQPPTASDGAT 120
           SGLQPAVRRLLQVKPEQVLLLPQPQAQNEEAAASSAQARLLQFRPDLRLLQPPTASDGAT
Sbjct: 61  SGLQPAVRRLLQVKPEQVLLLPQPQAQNEEAAASSAQARLLQFRPDLRLLQPPTASDGAT 120

Query: 121 SRPELHPVQPLALHVKAKKQKLGPSLDQSVGPRGAVETGPRASRVVKLEGPGPALGYFRG 180
           SRPELHPVQPLALHVKAKKQKLGPSLDQSVGPRGAVETGPRASRVVKLEGPGPALGYFRG
Sbjct: 121 SRPELHPVQPLALHVKAKKQKLGPSLDQSVGPRGAVETGPRASRVVKLEGPGPALGYFRG 180

Query: 181 DEKGKLEAEEVMRDSMQGGAGKSPAAIREGVIKTEEPERLLEDCRLGAEPASNGLVHGSA 240
           DEKGKLEAEEVMRDSMQGGAGKSPAAIREGVIKTEEPERLLEDCRLGAEPASNGLVHGSA
Sbjct: 181 DEKGKLEAEEVMRDSMQGGAGKSPAAIREGVIKTEEPERLLEDCRLGAEPASNGLVHGSA 240

Query: 241 EVILAPTSGAFGPHQQDLRIPLTLHTVPPGARIQFQGAPPSELIRLTKVPLTPVPTKMQS 300
           EVILAPTSGAFGPHQQDLRIPLTLHTVPPGARIQFQGAPPSELIRLTKVPLTPVPTKMQS
Sbjct: 241 EVILAPTSGAFGPHQQDLRIPLTLHTVPPGARIQFQGAPPSELIRLTKVPLTPVPTKMQS 300

Query: 301 LLEPSVKIETKDVPLTVLPSDAGIPDTPFSKDRNGHVKRPMNAFMVWARIHRPALAKANP 360
           LLEPSVKIETKDVPLTVLPSDAGIPDTPFSKDRNGHVKRPMNAFMVWARIHRPALAKANP
Sbjct: 301 LLEPSVKIETKDVPLTVLPSDAGIPDTPFSKDRNGHVKRPMNAFMVWARIHRPALAKANP 360

Query: 361 AANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKEKHREEFPGWVYQPRPGKRKRFPLSV 420
           AANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKEKHREEFPGWVYQPRPGKRKRFPLSV
Sbjct: 361 AANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKEKHREEFPGWVYQPRPGKRKRFPLSV 420

Query: 421 SNVFSGTTQNIISTNPTTVYPYRSPTYSVVIPSLQNPITHPV 462
           SNVFSGTTQNIISTNPTTVYPYRSPTYSVVIPSLQNPITHPV
Sbjct: 421 SNVFSGTTQNIISTNPTTVYPYRSPTYSVVIPSLQNPITHPV 462


>gi|169168396 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 134

 Score =  114 bits (284), Expect = 3e-25
 Identities = 63/95 (66%), Positives = 71/95 (74%), Gaps = 5/95 (5%)

Query: 1  MERARPEPPPQPRPLRPAPPPLPVEGTSFWAAAMEPPPSSPTLSAAASATLASSCGEAVA 60
          MERAR EPPPQP PL PAP  LPVEGTSFWAAA++ PPS P L AAA AT+ASSC E   
Sbjct: 1  MERARLEPPPQPHPLSPAPSLLPVEGTSFWAAAVKTPPSPPMLCAAAIATVASSCRE--- 57

Query: 61 SGLQP-AVRRLLQVKPEQVLLLPQPQAQNEEAAAS 94
           GL P A ++LL+VK EQVLLLPQP    + AA+S
Sbjct: 58 -GLVPCAAQQLLEVKLEQVLLLPQPHVPGKGAASS 91


>gi|239748690 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 134

 Score =  114 bits (284), Expect = 3e-25
 Identities = 63/95 (66%), Positives = 71/95 (74%), Gaps = 5/95 (5%)

Query: 1  MERARPEPPPQPRPLRPAPPPLPVEGTSFWAAAMEPPPSSPTLSAAASATLASSCGEAVA 60
          MERAR EPPPQP PL PAP  LPVEGTSFWAAA++ PPS P L AAA AT+ASSC E   
Sbjct: 1  MERARLEPPPQPHPLSPAPSLLPVEGTSFWAAAVKTPPSPPMLCAAAIATVASSCRE--- 57

Query: 61 SGLQP-AVRRLLQVKPEQVLLLPQPQAQNEEAAAS 94
           GL P A ++LL+VK EQVLLLPQP    + AA+S
Sbjct: 58 -GLVPCAAQQLLEVKLEQVLLLPQPHVPGKGAASS 91


>gi|239742713 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 134

 Score =  114 bits (284), Expect = 3e-25
 Identities = 63/95 (66%), Positives = 71/95 (74%), Gaps = 5/95 (5%)

Query: 1  MERARPEPPPQPRPLRPAPPPLPVEGTSFWAAAMEPPPSSPTLSAAASATLASSCGEAVA 60
          MERAR EPPPQP PL PAP  LPVEGTSFWAAA++ PPS P L AAA AT+ASSC E   
Sbjct: 1  MERARLEPPPQPHPLSPAPSLLPVEGTSFWAAAVKTPPSPPMLCAAAIATVASSCRE--- 57

Query: 61 SGLQP-AVRRLLQVKPEQVLLLPQPQAQNEEAAAS 94
           GL P A ++LL+VK EQVLLLPQP    + AA+S
Sbjct: 58 -GLVPCAAQQLLEVKLEQVLLLPQPHVPGKGAASS 91


>gi|13899269 SRY-box 7 [Homo sapiens]
          Length = 388

 Score = 92.0 bits (227), Expect = 1e-18
 Identities = 42/104 (40%), Positives = 63/104 (60%)

Query: 312 DVPLTVLPSDAGIPDTPFSKDRNGHVKRPMNAFMVWARIHRPALAKANPAANNAEISVQL 371
           D  L+   S   +P  P  K     ++RPMNAFMVWA+  R  LA  NP  +NAE+S  L
Sbjct: 20  DAELSDGQSPPAVPRPPGDKGSESRIRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKML 79

Query: 372 GLEWNKLSEEQKKPYYDEAQKIKEKHREEFPGWVYQPRPGKRKR 415
           G  W  L+  QK+PY DEA++++ +H +++P + Y+PR  K+ +
Sbjct: 80  GKSWKALTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRRKKQAK 123


>gi|4759162 SRY-box 14 [Homo sapiens]
          Length = 240

 Score = 92.0 bits (227), Expect = 1e-18
 Identities = 39/74 (52%), Positives = 56/74 (75%)

Query: 336 HVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKE 395
           H+KRPMNAFMVW+R  R  +A+ NP  +N+EIS +LG EW  LSE +K+PY DEA++++ 
Sbjct: 7   HIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKRLRA 66

Query: 396 KHREEFPGWVYQPR 409
           +H +E P + Y+PR
Sbjct: 67  QHMKEHPDYKYRPR 80


>gi|5902108 SRY-box 21 [Homo sapiens]
          Length = 276

 Score = 90.5 bits (223), Expect = 3e-18
 Identities = 38/74 (51%), Positives = 55/74 (74%)

Query: 336 HVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKE 395
           HVKRPMNAFMVW+R  R  +A+ NP  +N+EIS +LG EW  L+E +K+P+ DEA++++ 
Sbjct: 7   HVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRA 66

Query: 396 KHREEFPGWVYQPR 409
            H +E P + Y+PR
Sbjct: 67  MHMKEHPDYKYRPR 80


>gi|4507225 sex determining region Y [Homo sapiens]
          Length = 204

 Score = 89.0 bits (219), Expect = 9e-18
 Identities = 42/85 (49%), Positives = 58/85 (68%), Gaps = 1/85 (1%)

Query: 337 VKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKEK 396
           VKRPMNAF+VW+R  R  +A  NP   N+EIS QLG +W  L+E +K P++ EAQK++  
Sbjct: 60  VKRPMNAFIVWSRDQRRKMALENPRMRNSEISKQLGYQWKMLTEAEKWPFFQEAQKLQAM 119

Query: 397 HREEFPGWVYQPRPGKRKRFPLSVS 421
           HRE++P + Y+PR  K K  P + S
Sbjct: 120 HREKYPNYKYRPR-RKAKMLPKNCS 143


>gi|5902106 SRY-box 15 [Homo sapiens]
          Length = 233

 Score = 88.2 bits (217), Expect = 2e-17
 Identities = 44/121 (36%), Positives = 71/121 (58%), Gaps = 9/121 (7%)

Query: 337 VKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKEK 396
           VKRPMNAFMVW+   R  +A+ NP  +N+EIS +LG +W  L E++K+P+ +EA++++ +
Sbjct: 49  VKRPMNAFMVWSSAQRRQMAQQNPKMHNSEISKRLGAQWKLLDEDEKRPFVEEAKRLRAR 108

Query: 397 HREEFPGWVYQPRPGKR------KRFPLSVSNVFSGTT---QNIISTNPTTVYPYRSPTY 447
           H  ++P + Y+PR   +       R      N+ SG         +T P+  + YR P+Y
Sbjct: 109 HLRDYPDYKYRPRRKAKSSGAGPSRCGQGRGNLASGGPLWGPGYATTQPSRGFGYRPPSY 168

Query: 448 S 448
           S
Sbjct: 169 S 169


>gi|28195386 sex-determining region Y-box 2 [Homo sapiens]
          Length = 317

 Score = 87.4 bits (215), Expect = 3e-17
 Identities = 39/79 (49%), Positives = 56/79 (70%)

Query: 331 KDRNGHVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDEA 390
           K+    VKRPMNAFMVW+R  R  +A+ NP  +N+EIS +LG EW  LSE +K+P+ DEA
Sbjct: 35  KNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEA 94

Query: 391 QKIKEKHREEFPGWVYQPR 409
           ++++  H +E P + Y+PR
Sbjct: 95  KRLRALHMKEHPDYKYRPR 113


>gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens]
          Length = 391

 Score = 87.0 bits (214), Expect = 4e-17
 Identities = 38/80 (47%), Positives = 56/80 (70%)

Query: 330 SKDRNGHVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDE 389
           +K     VKRPMNAFMVW+R  R  +A+ NP  +N+EIS +LG EW  +SE +K+P+ DE
Sbjct: 44  AKANQDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFIDE 103

Query: 390 AQKIKEKHREEFPGWVYQPR 409
           A++++  H +E P + Y+PR
Sbjct: 104 AKRLRALHMKEHPDYKYRPR 123


>gi|4557853 transcription factor SOX9 [Homo sapiens]
          Length = 509

 Score = 86.3 bits (212), Expect = 6e-17
 Identities = 44/106 (41%), Positives = 63/106 (59%), Gaps = 2/106 (1%)

Query: 330 SKDRNGHVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDE 389
           S     HVKRPMNAFMVWA+  R  LA   P  +NAE+S  LG  W  L+E +K+P+ +E
Sbjct: 98  SSKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEE 157

Query: 390 AQKIKEKHREEFPGWVYQPRPGKRKRFPLSVSNVFSGTTQNIISTN 435
           A++++ +H+++ P + YQPR  +RK      +     T Q  IS N
Sbjct: 158 AERLRVQHKKDHPDYKYQPR--RRKSVKNGQAEAEEATEQTHISPN 201



 Score = 31.2 bits (69), Expect = 2.3
 Identities = 25/84 (29%), Positives = 33/84 (39%), Gaps = 3/84 (3%)

Query: 2   ERARPEPPPQPRPLRPAP--PPLPVEGTSFWAAAMEPPPSSPTLSAAASATLASSCGEAV 59
           ++A P PP QP    PAP  PP P        AA    P + TL+  +S    S      
Sbjct: 339 QQAPPPPPQQPPQAPPAPQAPPQPQAAPPQQPAAPPQQPQAHTLTTLSSEPGQSQRTHIK 398

Query: 60  ASGLQPA-VRRLLQVKPEQVLLLP 82
              L P+      Q  P+Q+   P
Sbjct: 399 TEQLSPSHYSEQQQHSPQQIAYSP 422


>gi|4507161 SRY-box 11 [Homo sapiens]
          Length = 441

 Score = 86.3 bits (212), Expect = 6e-17
 Identities = 36/84 (42%), Positives = 57/84 (67%)

Query: 326 DTPFSKDRNGHVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKP 385
           D  + K  +GH+KRPMNAFMVW++I R  + + +P  +NAEIS +LG  W  L + +K P
Sbjct: 38  DPDWCKTASGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIP 97

Query: 386 YYDEAQKIKEKHREEFPGWVYQPR 409
           +  EA++++ KH  ++P + Y+PR
Sbjct: 98  FIREAERLRLKHMADYPDYKYRPR 121


>gi|41406089 SRY-box 13 [Homo sapiens]
          Length = 622

 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 40/95 (42%), Positives = 60/95 (63%), Gaps = 8/95 (8%)

Query: 329 FSKDRNG-HVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYY 387
           F + RN  H+KRPMNAFMVWA+  R  + +A P  +N+ IS  LG  W  ++ ++K+PYY
Sbjct: 415 FPESRNSSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYY 474

Query: 388 DEAQKIKEKHREEFPGWVYQPRP-------GKRKR 415
           +E  ++  +H E++P + Y+PRP       GKR R
Sbjct: 475 EEQARLSRQHLEKYPDYKYKPRPKRTCIVEGKRLR 509


>gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens]
          Length = 474

 Score = 84.7 bits (208), Expect = 2e-16
 Identities = 39/91 (42%), Positives = 59/91 (64%), Gaps = 1/91 (1%)

Query: 320 SDAGIPDTP-FSKDRNGHVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKL 378
           S  G  D P + K  +GH+KRPMNAFMVW++I R  + + +P  +NAEIS +LG  W  L
Sbjct: 41  STGGKADDPSWCKTPSGHIKRPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLL 100

Query: 379 SEEQKKPYYDEAQKIKEKHREEFPGWVYQPR 409
            +  K P+  EA++++ KH  ++P + Y+PR
Sbjct: 101 KDSDKIPFIREAERLRLKHMADYPDYKYRPR 131


>gi|30179903 SRY (sex determining region Y)-box 8 [Homo sapiens]
          Length = 446

 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 38/77 (49%), Positives = 54/77 (70%)

Query: 336 HVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKE 395
           HVKRPMNAFMVWA+  R  LA   P  +NAE+S  LG  W  LSE +K+P+ +EA++++ 
Sbjct: 101 HVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRV 160

Query: 396 KHREEFPGWVYQPRPGK 412
           +H+++ P + YQPR  K
Sbjct: 161 QHKKDHPDYKYQPRRRK 177


>gi|30061556 SRY (sex determining region Y)-box 3 [Homo sapiens]
          Length = 446

 Score = 83.6 bits (205), Expect = 4e-16
 Identities = 35/73 (47%), Positives = 54/73 (73%)

Query: 337 VKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKEK 396
           VKRPMNAFMVW+R  R  +A  NP  +N+EIS +LG +W  L++ +K+P+ DEA++++  
Sbjct: 139 VKRPMNAFMVWSRGQRRKMALENPKMHNSEISKRLGADWKLLTDAEKRPFIDEAKRLRAV 198

Query: 397 HREEFPGWVYQPR 409
           H +E+P + Y+PR
Sbjct: 199 HMKEYPDYKYRPR 211



 Score = 33.9 bits (76), Expect = 0.35
 Identities = 39/146 (26%), Positives = 58/146 (39%), Gaps = 26/146 (17%)

Query: 7   EPPPQPRPLRPAPPPLP----VEGTSFWAAAMEPPPSSPTLSAAASATLASSCG------ 56
           +PP    P  P PP LP     +      + M PP +   ++ AA+A  AS  G      
Sbjct: 283 QPPSMSSP--PPPPALPPMHRYDMAGLQYSPMMPPGAQSYMNVAAAAAAASGYGGMAPSA 340

Query: 57  ---EAVASGLQP-------AVRRLLQVKPEQVLLLPQPQAQNEEAAASSAQARLLQFRPD 106
               A A G QP       A    + + P   ++  +P +     A+ S +A L   R  
Sbjct: 341 TAAAAAAYGQQPATAAAAAAAAAAMSLGPMGSVVKSEPSSPPPAIASHSQRACLGDLRDM 400

Query: 107 LRLLQPP--TASDGATSRP--ELHPV 128
           + +  PP   A+D A+  P   LH V
Sbjct: 401 ISMYLPPGGDAADAASPLPGGRLHGV 426


>gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Homo
           sapiens]
          Length = 841

 Score = 83.2 bits (204), Expect = 5e-16
 Identities = 34/75 (45%), Positives = 52/75 (69%)

Query: 336 HVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKE 395
           H+KRPMNAFMVWA+  R  + +A P  +N+ IS  LG  W  +S ++K+PYY+E  ++ +
Sbjct: 633 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSK 692

Query: 396 KHREEFPGWVYQPRP 410
            H E++P + Y+PRP
Sbjct: 693 IHLEKYPNYKYKPRP 707


>gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Homo
           sapiens]
          Length = 801

 Score = 83.2 bits (204), Expect = 5e-16
 Identities = 34/75 (45%), Positives = 52/75 (69%)

Query: 336 HVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKE 395
           H+KRPMNAFMVWA+  R  + +A P  +N+ IS  LG  W  +S ++K+PYY+E  ++ +
Sbjct: 593 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSK 652

Query: 396 KHREEFPGWVYQPRP 410
            H E++P + Y+PRP
Sbjct: 653 IHLEKYPNYKYKPRP 667


>gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo
           sapiens]
          Length = 804

 Score = 83.2 bits (204), Expect = 5e-16
 Identities = 34/75 (45%), Positives = 52/75 (69%)

Query: 336 HVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKE 395
           H+KRPMNAFMVWA+  R  + +A P  +N+ IS  LG  W  +S ++K+PYY+E  ++ +
Sbjct: 596 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSK 655

Query: 396 KHREEFPGWVYQPRP 410
            H E++P + Y+PRP
Sbjct: 656 IHLEKYPNYKYKPRP 670


>gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo
           sapiens]
          Length = 808

 Score = 83.2 bits (204), Expect = 5e-16
 Identities = 34/75 (45%), Positives = 52/75 (69%)

Query: 336 HVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKE 395
           H+KRPMNAFMVWA+  R  + +A P  +N+ IS  LG  W  +S ++K+PYY+E  ++ +
Sbjct: 600 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSK 659

Query: 396 KHREEFPGWVYQPRP 410
            H E++P + Y+PRP
Sbjct: 660 IHLEKYPNYKYKPRP 674


>gi|5902104 SRY (sex determining region Y)-box 10 [Homo sapiens]
          Length = 466

 Score = 82.4 bits (202), Expect = 9e-16
 Identities = 37/77 (48%), Positives = 53/77 (68%)

Query: 336 HVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKE 395
           HVKRPMNAFMVWA+  R  LA   P  +NAE+S  LG  W  L+E  K+P+ +EA++++ 
Sbjct: 103 HVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESDKRPFIEEAERLRM 162

Query: 396 KHREEFPGWVYQPRPGK 412
           +H+++ P + YQPR  K
Sbjct: 163 QHKKDHPDYKYQPRRRK 179


>gi|21264339 SRY (sex determining region Y)-box 12 [Homo sapiens]
          Length = 315

 Score = 82.4 bits (202), Expect = 9e-16
 Identities = 36/91 (39%), Positives = 58/91 (63%)

Query: 319 PSDAGIPDTPFSKDRNGHVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKL 378
           P++ G  +  + K  +GH+KRPMNAFMVW++  R  +    P  +NAEIS +LG  W  L
Sbjct: 22  PAEEGAREPGWCKTPSGHIKRPMNAFMVWSQHERRKIMDQWPDMHNAEISKRLGRRWQLL 81

Query: 379 SEEQKKPYYDEAQKIKEKHREEFPGWVYQPR 409
            + +K P+  EA++++ KH  ++P + Y+PR
Sbjct: 82  QDSEKIPFVREAERLRLKHMADYPDYKYRPR 112


>gi|11967991 SRY-box 17 [Homo sapiens]
          Length = 414

 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 36/96 (37%), Positives = 62/96 (64%), Gaps = 1/96 (1%)

Query: 319 PSDAGIPDTPFSKDRN-GHVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNK 377
           P+++G P     + +    ++RPMNAFMVWA+  R  LA+ NP  +NAE+S  LG  W  
Sbjct: 49  PANSGAPAGAAGRAKGESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWKA 108

Query: 378 LSEEQKKPYYDEAQKIKEKHREEFPGWVYQPRPGKR 413
           L+  +K+P+ +EA++++ +H ++ P + Y+PR  K+
Sbjct: 109 LTLAEKRPFVEEAERLRVQHMQDHPNYKYRPRRRKQ 144


>gi|30061558 SRY (sex determining region Y)-box 5 isoform c [Homo
           sapiens]
          Length = 377

 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 36/95 (37%), Positives = 60/95 (63%), Gaps = 6/95 (6%)

Query: 322 AGIPDTPFSKDRNG------HVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEW 375
           AG+ ++   ++  G      H+KRPMNAFMVWA+  R  + +A P  +N+ IS  LG  W
Sbjct: 149 AGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRW 208

Query: 376 NKLSEEQKKPYYDEAQKIKEKHREEFPGWVYQPRP 410
             ++  +K+PYY+E  ++ ++H E++P + Y+PRP
Sbjct: 209 KAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRP 243


>gi|23308715 SRY (sex determining region Y)-box 5 isoform b [Homo
           sapiens]
          Length = 750

 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 36/95 (37%), Positives = 60/95 (63%), Gaps = 6/95 (6%)

Query: 322 AGIPDTPFSKDRNG------HVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEW 375
           AG+ ++   ++  G      H+KRPMNAFMVWA+  R  + +A P  +N+ IS  LG  W
Sbjct: 522 AGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRW 581

Query: 376 NKLSEEQKKPYYDEAQKIKEKHREEFPGWVYQPRP 410
             ++  +K+PYY+E  ++ ++H E++P + Y+PRP
Sbjct: 582 KAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRP 616


>gi|23308713 SRY (sex determining region Y)-box 5 isoform a [Homo
           sapiens]
          Length = 763

 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 36/95 (37%), Positives = 60/95 (63%), Gaps = 6/95 (6%)

Query: 322 AGIPDTPFSKDRNG------HVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEW 375
           AG+ ++   ++  G      H+KRPMNAFMVWA+  R  + +A P  +N+ IS  LG  W
Sbjct: 535 AGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRW 594

Query: 376 NKLSEEQKKPYYDEAQKIKEKHREEFPGWVYQPRP 410
             ++  +K+PYY+E  ++ ++H E++P + Y+PRP
Sbjct: 595 KAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRP 629


>gi|8924248 SRY-box 18 [Homo sapiens]
          Length = 384

 Score = 79.0 bits (193), Expect = 1e-14
 Identities = 33/79 (41%), Positives = 54/79 (68%)

Query: 337 VKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKEK 396
           ++RPMNAFMVWA+  R  LA+ NP  +NA +S  LG  W +L+  +K+P+ +EA++++ +
Sbjct: 85  IRRPMNAFMVWAKDERKRLAQQNPDLHNAVLSKMLGKAWKELNAAEKRPFVEEAERLRVQ 144

Query: 397 HREEFPGWVYQPRPGKRKR 415
           H  + P + Y+PR  K+ R
Sbjct: 145 HLRDHPNYKYRPRRKKQAR 163


>gi|226371764 transcription factor 7-like 2 isoform 1 [Homo sapiens]
          Length = 602

 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 47/182 (25%), Positives = 83/182 (45%), Gaps = 14/182 (7%)

Query: 235 LVHGSAEVILAPTSGAFG-PHQQDLRIPLTLHTVPPGARIQFQGAPPSELIRLTKVPLTP 293
           LV    + +   T+G F  P+   L +  ++   PP         PP   +  T +P   
Sbjct: 260 LVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHM------VPPHHTLHTTGIPHPA 313

Query: 294 VPTKMQSLLEPSVKIETKDVPLTVLPSDAGIPDTPFSKDRNGHVKRPMNAFMVWARIHRP 353
           + T       P+VK E+    +  L S          + +  H+K+P+NAFM++ +  R 
Sbjct: 314 IVT-------PTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRA 366

Query: 354 ALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKEKHREEFPGWVYQPRPGKR 413
            +        +A I+  LG  W+ LS E++  YY+ A+K ++ H + +PGW  +   GK+
Sbjct: 367 KVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKK 426

Query: 414 KR 415
           K+
Sbjct: 427 KK 428


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.132    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,064,474
Number of Sequences: 37866
Number of extensions: 1395820
Number of successful extensions: 11695
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 252
Number of HSP's successfully gapped in prelim test: 447
Number of HSP's that attempted gapping in prelim test: 7894
Number of HSP's gapped (non-prelim): 3003
length of query: 501
length of database: 18,247,518
effective HSP length: 106
effective length of query: 395
effective length of database: 14,233,722
effective search space: 5622320190
effective search space used: 5622320190
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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