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Search of human proteins with 57165436
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|57165436 serine/threonine kinase 16 [Homo sapiens]
(305 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|57165436 serine/threonine kinase 16 [Homo sapiens] 631 0.0
gi|157384971 cyclin G associated kinase [Homo sapiens] 120 1e-27
gi|148277037 AP2 associated kinase 1 [Homo sapiens] 112 3e-25
gi|38787935 BMP-2 inducible kinase isoform a [Homo sapiens] 108 5e-24
gi|38787904 BMP-2 inducible kinase isoform b [Homo sapiens] 108 5e-24
gi|41872673 NIMA-related kinase 1 [Homo sapiens] 102 6e-22
gi|55743134 ribosomal protein S6 kinase, 90kDa, polypeptide 1 is... 98 8e-21
gi|20149547 ribosomal protein S6 kinase, 90kDa, polypeptide 1 is... 98 8e-21
gi|148839316 NIMA-related kinase 4 [Homo sapiens] 96 3e-20
gi|55743136 ribosomal protein S6 kinase, 90kDa, polypeptide 2 is... 93 3e-19
gi|19923570 ribosomal protein S6 kinase, 90kDa, polypeptide 2 is... 93 3e-19
gi|83627721 NIMA-related kinase 5 [Homo sapiens] 92 4e-19
gi|191252782 p21-activated kinase 6 [Homo sapiens] 92 4e-19
gi|191252780 p21-activated kinase 6 [Homo sapiens] 92 4e-19
gi|9910476 p21-activated kinase 6 [Homo sapiens] 92 4e-19
gi|4759050 ribosomal protein S6 kinase, 90kDa, polypeptide 3 [Ho... 91 1e-18
gi|19424132 NIMA-related kinase 7 [Homo sapiens] 91 1e-18
gi|30039692 NIMA-related kinase 8 [Homo sapiens] 91 1e-18
gi|29826329 p21-activated kinase 7 [Homo sapiens] 90 3e-18
gi|24308191 p21-activated kinase 7 [Homo sapiens] 90 3e-18
gi|222418622 NIMA-related kinase 6 isoform 1 [Homo sapiens] 89 4e-18
gi|19923407 NIMA-related kinase 6 isoform 2 [Homo sapiens] 89 4e-18
gi|225735561 NIMA-related kinase 3 isoform b [Homo sapiens] 89 6e-18
gi|23510391 NIMA-related kinase 3 isoform a [Homo sapiens] 89 6e-18
gi|23510393 NIMA-related kinase 3 isoform a [Homo sapiens] 89 6e-18
gi|93004081 polo-like kinase 2 [Homo sapiens] 88 8e-18
gi|38327572 serine/threonine protein kinase 6 [Homo sapiens] 88 1e-17
gi|38327570 serine/threonine protein kinase 6 [Homo sapiens] 88 1e-17
gi|38327568 serine/threonine protein kinase 6 [Homo sapiens] 88 1e-17
gi|38327566 serine/threonine protein kinase 6 [Homo sapiens] 88 1e-17
>gi|57165436 serine/threonine kinase 16 [Homo sapiens]
Length = 305
Score = 631 bits (1628), Expect = 0.0
Identities = 305/305 (100%), Positives = 305/305 (100%)
Query: 1 MGHALCVCSRGTVIIDNKRYLFIQKLGEGGFSYVDLVEGLHDGHFYALKRILCHEQQDRE 60
MGHALCVCSRGTVIIDNKRYLFIQKLGEGGFSYVDLVEGLHDGHFYALKRILCHEQQDRE
Sbjct: 1 MGHALCVCSRGTVIIDNKRYLFIQKLGEGGFSYVDLVEGLHDGHFYALKRILCHEQQDRE 60
Query: 61 EAQREADMHRLFNHPNILRLVAYCLRERGAKHEAWLLLPFFKRGTLWNEIERLKDKGNFL 120
EAQREADMHRLFNHPNILRLVAYCLRERGAKHEAWLLLPFFKRGTLWNEIERLKDKGNFL
Sbjct: 61 EAQREADMHRLFNHPNILRLVAYCLRERGAKHEAWLLLPFFKRGTLWNEIERLKDKGNFL 120
Query: 121 TEDQILWLLLGICRGLEAIHAKGYAHRDLKPTNILLGDEGQPVLMDLGSMNQACIHVEGS 180
TEDQILWLLLGICRGLEAIHAKGYAHRDLKPTNILLGDEGQPVLMDLGSMNQACIHVEGS
Sbjct: 121 TEDQILWLLLGICRGLEAIHAKGYAHRDLKPTNILLGDEGQPVLMDLGSMNQACIHVEGS 180
Query: 181 RQALTLQDWAAQRCTISYRAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQ 240
RQALTLQDWAAQRCTISYRAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQ
Sbjct: 181 RQALTLQDWAAQRCTISYRAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQ 240
Query: 241 KGDSVALAVQNQLSIPQSPRHSSALRQLLNSMMTVDPHQRPHIPLLLSQLEALQPPAPGQ 300
KGDSVALAVQNQLSIPQSPRHSSALRQLLNSMMTVDPHQRPHIPLLLSQLEALQPPAPGQ
Sbjct: 241 KGDSVALAVQNQLSIPQSPRHSSALRQLLNSMMTVDPHQRPHIPLLLSQLEALQPPAPGQ 300
Query: 301 HTTQI 305
HTTQI
Sbjct: 301 HTTQI 305
>gi|157384971 cyclin G associated kinase [Homo sapiens]
Length = 1311
Score = 120 bits (301), Expect = 1e-27
Identities = 89/296 (30%), Positives = 151/296 (51%), Gaps = 25/296 (8%)
Query: 12 TVIIDNKRYLFIQKLGEGGFSYVDLVEGLHDGHFYALKRILCHEQQ-DREEAQREADMHR 70
TV + R + L EGGF++V + + G YALKR+L +E++ +R Q M +
Sbjct: 32 TVELGELRLRVRRVLAEGGFAFVYEAQDVGSGREYALKRLLSNEEEKNRAIIQEVCFMKK 91
Query: 71 LFNHPNILRLVAYCLRERGAKHEA------WLLLPFFKRGTLWNEIERLKDKGNFLTEDQ 124
L HPNI V +C K E+ +LLL +G L +++++ +G L+ D
Sbjct: 92 LSGHPNI---VQFCSAASIGKEESDTGQAEFLLLTELCKGQLVEFLKKMESRGP-LSCDT 147
Query: 125 ILWLLLGICRGLEAIHAKG--YAHRDLKPTNILLGDEGQPVLMDLGSMNQACIHVEGS-- 180
+L + CR ++ +H + HRDLK N+LL ++G L D GS + + S
Sbjct: 148 VLKIFYQTCRAVQHMHRQKPPIIHRDLKVENLLLSNQGTIKLCDFGSATTISHYPDYSWS 207
Query: 181 --RQALTLQDWAAQRCTISYRAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMV 238
R+AL +++ + T YR PE+ + S+ I E+ D+W+LGC+LY + F + P++
Sbjct: 208 AQRRAL-VEEEITRNTTPMYRTPEIIDLYSNFPIGEKQDIWALGCILYLLCFRQHPFE-- 264
Query: 239 FQKGDSVALAVQN-QLSIPQSPRHSSALRQLLNSMMTVDPHQRPHIPLLLSQLEAL 293
D L + N + SIP + L+ +M+ V+P +R I ++ QL+ +
Sbjct: 265 ----DGAKLRIVNGKYSIPPHDTQYTVFHSLIRAMLQVNPEERLSIAEVVHQLQEI 316
>gi|148277037 AP2 associated kinase 1 [Homo sapiens]
Length = 961
Score = 112 bits (281), Expect = 3e-25
Identities = 80/263 (30%), Positives = 129/263 (49%), Gaps = 15/263 (5%)
Query: 26 LGEGGFSYVDLVEGLHDGHFYALKRILCHEQQDREEAQREADMHR-LFNHPNILRLVAYC 84
L EGGF+ V LV +G ALKR+ + + D + +RE + R L H NI+ +
Sbjct: 52 LAEGGFAIVFLVR-TSNGMKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDSS 110
Query: 85 LRE--RGAKHEAWLLLPFFKRGTLWNEIERLKDKGNFLTEDQILWLLLGICRGLEAIHA- 141
+ G E +L+ F + G + N + + G TE+++L + C + +H
Sbjct: 111 INNVSSGDVWEVLILMDFCRGGQVVNLMNQRLQTG--FTENEVLQIFCDTCEAVARLHQC 168
Query: 142 -KGYAHRDLKPTNILLGDEGQPVLMDLGSMNQACIHVEGSRQALTLQDWAAQRCTISYRA 200
HRDLK NILL D G VL D GS + + + ++D + T+SYRA
Sbjct: 169 KTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQ-TEGVNAVEDEIKKYTTLSYRA 227
Query: 201 PELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQKGDSVALAVQNQLSIPQSPR 260
PE+ ++ S +I + D+W+LGC+LY + + P+ G+S +IP + R
Sbjct: 228 PEMVNLYSGKIITTKADIWALGCLLYKLCYFTLPF------GESQVAICDGNFTIPDNSR 281
Query: 261 HSSALRQLLNSMMTVDPHQRPHI 283
+S + L+ M+ DP +RP I
Sbjct: 282 YSQDMHCLIRYMLEPDPDKRPDI 304
>gi|38787935 BMP-2 inducible kinase isoform a [Homo sapiens]
Length = 1161
Score = 108 bits (271), Expect = 5e-24
Identities = 79/264 (29%), Positives = 124/264 (46%), Gaps = 14/264 (5%)
Query: 24 QKLGEGGFSYVDLVEGLHDGHFYALKRILCHEQQDREEAQREAD-MHRLFNHPNILRLVA 82
+ L EGGFS V LV H G ALKR+ + D +RE M L H NI+ +
Sbjct: 55 ESLAEGGFSTVFLVR-THGGIRCALKRMYVNNMPDLNVCKREITIMKELSGHKNIVGYLD 113
Query: 83 YCLRERGAK-HEAWLLLPFFKRGTLWNEIERLKDKGNFLTEDQILWLLLGICRGLEAIHA 141
+ E +L+ + + G + N++ + G TE ++L + C + +H
Sbjct: 114 CAVNSISDNVWEVLILMEYCRAGQVVNQMNKKLQTG--FTEPEVLQIFCDTCEAVARLHQ 171
Query: 142 --KGYAHRDLKPTNILLGDEGQPVLMDLGSMNQACIHVEGSRQALTLQDWAAQRCTISYR 199
HRDLK NILL D G VL D GS ++ + + +++ + T+SYR
Sbjct: 172 CKTPIIHRDLKVENILLNDGGNYVLCDFGSATNKFLNPQKDGVNV-VEEEIKKYTTLSYR 230
Query: 200 APELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQKGDSVALAVQNQLSIPQSP 259
APE+ ++ I + D+W+LGC+LY + F P+ G+S +IP +
Sbjct: 231 APEMINLYGGKPITTKADIWALGCLLYKLCFFTLPF------GESQVAICDGNFTIPDNS 284
Query: 260 RHSSALRQLLNSMMTVDPHQRPHI 283
R+S + L+ M+ DP RP I
Sbjct: 285 RYSRNIHCLIRFMLEPDPEHRPDI 308
>gi|38787904 BMP-2 inducible kinase isoform b [Homo sapiens]
Length = 662
Score = 108 bits (271), Expect = 5e-24
Identities = 79/264 (29%), Positives = 124/264 (46%), Gaps = 14/264 (5%)
Query: 24 QKLGEGGFSYVDLVEGLHDGHFYALKRILCHEQQDREEAQREAD-MHRLFNHPNILRLVA 82
+ L EGGFS V LV H G ALKR+ + D +RE M L H NI+ +
Sbjct: 55 ESLAEGGFSTVFLVR-THGGIRCALKRMYVNNMPDLNVCKREITIMKELSGHKNIVGYLD 113
Query: 83 YCLRERGAK-HEAWLLLPFFKRGTLWNEIERLKDKGNFLTEDQILWLLLGICRGLEAIHA 141
+ E +L+ + + G + N++ + G TE ++L + C + +H
Sbjct: 114 CAVNSISDNVWEVLILMEYCRAGQVVNQMNKKLQTG--FTEPEVLQIFCDTCEAVARLHQ 171
Query: 142 --KGYAHRDLKPTNILLGDEGQPVLMDLGSMNQACIHVEGSRQALTLQDWAAQRCTISYR 199
HRDLK NILL D G VL D GS ++ + + +++ + T+SYR
Sbjct: 172 CKTPIIHRDLKVENILLNDGGNYVLCDFGSATNKFLNPQKDGVNV-VEEEIKKYTTLSYR 230
Query: 200 APELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQKGDSVALAVQNQLSIPQSP 259
APE+ ++ I + D+W+LGC+LY + F P+ G+S +IP +
Sbjct: 231 APEMINLYGGKPITTKADIWALGCLLYKLCFFTLPF------GESQVAICDGNFTIPDNS 284
Query: 260 RHSSALRQLLNSMMTVDPHQRPHI 283
R+S + L+ M+ DP RP I
Sbjct: 285 RYSRNIHCLIRFMLEPDPEHRPDI 308
>gi|41872673 NIMA-related kinase 1 [Homo sapiens]
Length = 1258
Score = 102 bits (253), Expect = 6e-22
Identities = 77/274 (28%), Positives = 132/274 (48%), Gaps = 22/274 (8%)
Query: 18 KRYLFIQKLGEGGFSYVDLVEGLHDGHFYALKRILCHEQ--QDREEAQREADMHRLFNHP 75
++Y+ +QK+GEG F LV+ DG Y +K I ++REE++RE + HP
Sbjct: 2 EKYVRLQKIGEGSFGKAILVKSTEDGRQYVIKEINISRMSSKEREESRREVAVLANMKHP 61
Query: 76 NILRLVAYCLRERGAKHEAWLLLPFFKRGTLWNEIERLKDKGNFLTEDQILWLLLGICRG 135
NI++ E G+ ++++ + + G L+ I KG EDQIL + IC
Sbjct: 62 NIVQY-RESFEENGS---LYIVMDYCEGGDLFKRINA--QKGVLFQEDQILDWFVQICLA 115
Query: 136 LEAIHAKGYAHRDLKPTNILLGDEGQPVLMDLGSMNQACIHVEGSRQALTLQDWAAQRCT 195
L+ +H + HRD+K NI L +G L D G VE +R + T
Sbjct: 116 LKHVHDRKILHRDIKSQNIFLTKDGTVQLGDFGIARVLNSTVELARTCIG---------T 166
Query: 196 ISYRAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQKGDSVALAVQNQLSI 255
Y +PE+ + + + ++D+W+LGCVLY + + ++ K ++ L + +
Sbjct: 167 PYYLSPEICENKPY---NNKSDIWALGCVLYELCTLKHAFEAGSMK--NLVLKIISGSFP 221
Query: 256 PQSPRHSSALRQLLNSMMTVDPHQRPHIPLLLSQ 289
P S +S LR L++ + +P RP + +L +
Sbjct: 222 PVSLHYSYDLRSLVSQLFKRNPRDRPSVNSILEK 255
>gi|55743134 ribosomal protein S6 kinase, 90kDa, polypeptide 1
isoform b [Homo sapiens]
Length = 744
Score = 98.2 bits (243), Expect = 8e-21
Identities = 79/276 (28%), Positives = 135/276 (48%), Gaps = 30/276 (10%)
Query: 11 GTVIIDNKRYLFIQKLGEGGFSYVDLVEGL---HDGHFYALKRI--LCHEQQDREEAQRE 65
G+ D + ++ LG+G F V LV + GH YA+K + + +DR + E
Sbjct: 62 GSEKADPSHFELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVRDRVRTKME 121
Query: 66 ADMHRLFNHPNILRLVAYCLRERGAKHEAWLLLPFFKRGTLWNEIERLKDKGNFLTEDQI 125
D+ NHP +++L Y + G + +L+L F + G L+ + K TE+ +
Sbjct: 122 RDILADVNHPFVVKL-HYAFQTEG---KLYLILDFLRGGDLFTRLS----KEVMFTEEDV 173
Query: 126 LWLLLGICRGLEAIHAKGYAHRDLKPTNILLGDEGQPVLMDLGSMNQACIHVEGSRQALT 185
+ L + GL+ +H+ G +RDLKP NILL +EG L D G S++A+
Sbjct: 174 KFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGL----------SKEAID 223
Query: 186 LQDWAAQRC-TISYRAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQKGDS 244
+ A C T+ Y APE+ + Q H D WS G +++ M+ G P+ +K ++
Sbjct: 224 HEKKAYSFCGTVEYMAPEVVNRQGH---SHSADWWSYGVLMFEMLTGSLPFQGKDRK-ET 279
Query: 245 VALAVQNQLSIPQSPRHSSALRQLLNSMMTVDPHQR 280
+ L ++ +L +PQ S+ + LL ++ +P R
Sbjct: 280 MTLILKAKLGMPQF--LSTEAQSLLRALFKRNPANR 313
Score = 76.6 bits (187), Expect = 2e-14
Identities = 82/303 (27%), Positives = 136/303 (44%), Gaps = 39/303 (12%)
Query: 3 HALCVCSRGTVIIDNKRYLFIQKLGEGGFSYVDLVEGLHDGHFYALKRILCHEQQDREEA 62
H++ G ++ + Y+ + +G G +S YA+K I ++ R+ +
Sbjct: 410 HSVVQQLHGKNLVFSDGYVVKETIGVGSYSECKRCVHKATNMEYAVKVI---DKSKRDPS 466
Query: 63 QREADMHRLFNHPNILRLVAYCLRERGAKHEAWLLLPFFKRGTLWNEIERLKDKGNFLTE 122
+ + R HPNI+ L KH +L+ + G L ++I R K F +E
Sbjct: 467 EEIEILLRYGQHPNIITLKDVY---DDGKH-VYLVTELMRGGELLDKILRQK----FFSE 518
Query: 123 DQILWLLLGICRGLEAIHAKGYAHRDLKPTNILLGDEGQPVLMDLGSMNQACIHV--EGS 180
+ ++L I + +E +H++G HRDLKP+NIL DE S N C+ + G
Sbjct: 519 REASFVLHTIGKTVEYLHSQGVVHRDLKPSNILYVDE---------SGNPECLRICDFGF 569
Query: 181 RQALTLQDWAAQR--CTISYRAPELFSVQSHCVIDERTDVWSLGCVLYAMM-----FGEG 233
+ L ++ T ++ APE+ Q + DE D+WSLG +LY M+ F G
Sbjct: 570 AKQLRAENGLLMTPCYTANFVAPEVLKRQGY---DEGCDIWSLGILLYTMLAGYTPFANG 626
Query: 234 PYDMVFQKGDSVALAVQNQLSIPQSPRHSSALRQLLNSMMTVDPHQRPHIPLLLSQLEAL 293
P D + + + + LS S + L++ M+ VDPHQR L+ + L
Sbjct: 627 PSDTPEEILTRIG-SGKFTLSGGNWNTVSETAKDLVSKMLHVDPHQR------LTAKQVL 679
Query: 294 QPP 296
Q P
Sbjct: 680 QHP 682
>gi|20149547 ribosomal protein S6 kinase, 90kDa, polypeptide 1
isoform a [Homo sapiens]
Length = 735
Score = 98.2 bits (243), Expect = 8e-21
Identities = 79/276 (28%), Positives = 135/276 (48%), Gaps = 30/276 (10%)
Query: 11 GTVIIDNKRYLFIQKLGEGGFSYVDLVEGL---HDGHFYALKRI--LCHEQQDREEAQRE 65
G+ D + ++ LG+G F V LV + GH YA+K + + +DR + E
Sbjct: 53 GSEKADPSHFELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVRDRVRTKME 112
Query: 66 ADMHRLFNHPNILRLVAYCLRERGAKHEAWLLLPFFKRGTLWNEIERLKDKGNFLTEDQI 125
D+ NHP +++L Y + G + +L+L F + G L+ + K TE+ +
Sbjct: 113 RDILADVNHPFVVKL-HYAFQTEG---KLYLILDFLRGGDLFTRLS----KEVMFTEEDV 164
Query: 126 LWLLLGICRGLEAIHAKGYAHRDLKPTNILLGDEGQPVLMDLGSMNQACIHVEGSRQALT 185
+ L + GL+ +H+ G +RDLKP NILL +EG L D G S++A+
Sbjct: 165 KFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGL----------SKEAID 214
Query: 186 LQDWAAQRC-TISYRAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQKGDS 244
+ A C T+ Y APE+ + Q H D WS G +++ M+ G P+ +K ++
Sbjct: 215 HEKKAYSFCGTVEYMAPEVVNRQGH---SHSADWWSYGVLMFEMLTGSLPFQGKDRK-ET 270
Query: 245 VALAVQNQLSIPQSPRHSSALRQLLNSMMTVDPHQR 280
+ L ++ +L +PQ S+ + LL ++ +P R
Sbjct: 271 MTLILKAKLGMPQF--LSTEAQSLLRALFKRNPANR 304
Score = 76.6 bits (187), Expect = 2e-14
Identities = 82/303 (27%), Positives = 136/303 (44%), Gaps = 39/303 (12%)
Query: 3 HALCVCSRGTVIIDNKRYLFIQKLGEGGFSYVDLVEGLHDGHFYALKRILCHEQQDREEA 62
H++ G ++ + Y+ + +G G +S YA+K I ++ R+ +
Sbjct: 401 HSVVQQLHGKNLVFSDGYVVKETIGVGSYSECKRCVHKATNMEYAVKVI---DKSKRDPS 457
Query: 63 QREADMHRLFNHPNILRLVAYCLRERGAKHEAWLLLPFFKRGTLWNEIERLKDKGNFLTE 122
+ + R HPNI+ L KH +L+ + G L ++I R K F +E
Sbjct: 458 EEIEILLRYGQHPNIITLKDVY---DDGKH-VYLVTELMRGGELLDKILRQK----FFSE 509
Query: 123 DQILWLLLGICRGLEAIHAKGYAHRDLKPTNILLGDEGQPVLMDLGSMNQACIHV--EGS 180
+ ++L I + +E +H++G HRDLKP+NIL DE S N C+ + G
Sbjct: 510 REASFVLHTIGKTVEYLHSQGVVHRDLKPSNILYVDE---------SGNPECLRICDFGF 560
Query: 181 RQALTLQDWAAQR--CTISYRAPELFSVQSHCVIDERTDVWSLGCVLYAMM-----FGEG 233
+ L ++ T ++ APE+ Q + DE D+WSLG +LY M+ F G
Sbjct: 561 AKQLRAENGLLMTPCYTANFVAPEVLKRQGY---DEGCDIWSLGILLYTMLAGYTPFANG 617
Query: 234 PYDMVFQKGDSVALAVQNQLSIPQSPRHSSALRQLLNSMMTVDPHQRPHIPLLLSQLEAL 293
P D + + + + LS S + L++ M+ VDPHQR L+ + L
Sbjct: 618 PSDTPEEILTRIG-SGKFTLSGGNWNTVSETAKDLVSKMLHVDPHQR------LTAKQVL 670
Query: 294 QPP 296
Q P
Sbjct: 671 QHP 673
>gi|148839316 NIMA-related kinase 4 [Homo sapiens]
Length = 841
Score = 96.3 bits (238), Expect = 3e-20
Identities = 76/274 (27%), Positives = 133/274 (48%), Gaps = 25/274 (9%)
Query: 20 YLFIQKLGEGGFSYVDLVEGLHDGHFYALKRILCHEQQDREE--AQREADMHRLFNHPNI 77
Y +++ +G+G + V LV+ DG Y +K++ RE A++EA + HPNI
Sbjct: 6 YCYLRVVGKGSYGEVTLVKHRRDGKQYVIKKLNLRNASSRERRAAEQEAQLLSQLKHPNI 65
Query: 78 LRLVAYCLRERGAKHEAWLLLPFFKRGTLWNEIERLKDKGNFLTEDQILWLLLGICRGLE 137
V Y G ++++ F + G L+ +++ + KG L E+Q++ + I L+
Sbjct: 66 ---VTYKESWEGGDGLLYIVMGFCEGGDLYRKLK--EQKGQLLPENQVVEWFVQIAMALQ 120
Query: 138 AIHAKGYAHRDLKPTNILLGDEGQPVLMDLGSMNQACIHVEGSRQALTLQDWAAQRCTIS 197
+H K HRDLK N+ L + ++ +G + A + A TL T
Sbjct: 121 YLHEKHILHRDLKTQNVFL---TRTNIIKVGDLGIARVLENHCDMASTLIG------TPY 171
Query: 198 YRAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQKGDSVALAVQ-NQLSIP 256
Y +PELFS + + + ++DVW+LGC +Y M F D +L + + +P
Sbjct: 172 YMSPELFSNKPY---NYKSDVWALGCCVYEM----ATLKHAFNAKDMNSLVYRIIEGKLP 224
Query: 257 QSPR-HSSALRQLLNSMMTVDPHQRPHIPLLLSQ 289
PR +S L +L+ +M++ P +RP + +L Q
Sbjct: 225 PMPRDYSPELAELIRTMLSKRPEERPSVRSILRQ 258
>gi|55743136 ribosomal protein S6 kinase, 90kDa, polypeptide 2
isoform b [Homo sapiens]
Length = 741
Score = 93.2 bits (230), Expect = 3e-19
Identities = 76/260 (29%), Positives = 130/260 (50%), Gaps = 28/260 (10%)
Query: 16 DNKRYLFIQKLGEGGFSYVDLV---EGLHDGHFYALKRI--LCHEQQDREEAQREADMHR 70
D ++ ++ LG+G + V LV +G G YA+K + + +DR ++ E D+
Sbjct: 63 DPSQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILA 122
Query: 71 LFNHPNILRLVAYCLRERGAKHEAWLLLPFFKRGTLWNEIERLKDKGNFLTEDQILWLLL 130
NHP I++L Y + G + +L+L F + G L+ + K TE+ + + L
Sbjct: 123 EVNHPFIVKL-HYAFQTEG---KLYLILDFLRGGDLFTRLS----KEVMFTEEDVKFYLA 174
Query: 131 GICRGLEAIHAKGYAHRDLKPTNILLGDEGQPVLMDLGSMNQACIHVEGSRQALTLQDWA 190
+ L+ +H+ G +RDLKP NILL +EG + D G +A H ++A +
Sbjct: 175 ELALALDHLHSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDH---DKRAYSFCG-- 229
Query: 191 AQRCTISYRAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQKGDSVALAVQ 250
TI Y APE+ + + H + D WS G +++ M+ G P+ +K +++AL ++
Sbjct: 230 ----TIEYMAPEVVNRRGH---TQSADWWSFGVLMFEMLTGSLPFQGKDRK-ETMALILK 281
Query: 251 NQLSIPQ--SPRHSSALRQL 268
+L +PQ S S LR L
Sbjct: 282 AKLGMPQFLSGEAQSLLRAL 301
Score = 68.2 bits (165), Expect = 9e-12
Identities = 73/262 (27%), Positives = 122/262 (46%), Gaps = 43/262 (16%)
Query: 46 YALKRILCHEQQDREEAQREADMHRLFNHPNILRLVAYCLRERGAKHEAWLLLPFFKRGT 105
YA+K I ++ R+ ++ + R HPNI+ L + + G +L++ + G
Sbjct: 449 YAVKII---DKSKRDPSEEIEILLRYGQHPNIITLKD--VYDDGKF--VYLVMELMRGGE 501
Query: 106 LWNEIERLKDKGNFLTEDQILWLLLGICRGLEAIHAKGYAHRDLKPTNILLGDE-GQPVL 164
L + I R + + +E + +L I + ++ +H++G HRDLKP+NIL DE G P
Sbjct: 502 LLDRILRQR----YFSEREASDVLCTITKTMDYLHSQGVVHRDLKPSNILYRDESGSPES 557
Query: 165 MDLGSMNQACIHVEGSRQALTLQDWAAQRCTISYRAPELFSVQSHCVIDERTDVWSLGCV 224
+ + A G+ +T T ++ APE+ Q + D D+WSLG +
Sbjct: 558 IRVCDFGFAKQLRAGNGLLMT------PCYTANFVAPEVLKRQGY---DAACDIWSLGIL 608
Query: 225 LYAMM-----FGEGPYD-----MVFQKGDSVALAVQNQLSIPQSPRHSSALRQLLNSMMT 274
LY M+ F GP D + AL+ N SI S A + +++ M+
Sbjct: 609 LYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSI------SDAAKDVVSKMLH 662
Query: 275 VDPHQRPHIPLLLSQLEALQPP 296
VDPHQR L+ ++ L+ P
Sbjct: 663 VDPHQR------LTAMQVLKHP 678
>gi|19923570 ribosomal protein S6 kinase, 90kDa, polypeptide 2
isoform a [Homo sapiens]
Length = 733
Score = 93.2 bits (230), Expect = 3e-19
Identities = 76/260 (29%), Positives = 130/260 (50%), Gaps = 28/260 (10%)
Query: 16 DNKRYLFIQKLGEGGFSYVDLV---EGLHDGHFYALKRI--LCHEQQDREEAQREADMHR 70
D ++ ++ LG+G + V LV +G G YA+K + + +DR ++ E D+
Sbjct: 55 DPSQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILA 114
Query: 71 LFNHPNILRLVAYCLRERGAKHEAWLLLPFFKRGTLWNEIERLKDKGNFLTEDQILWLLL 130
NHP I++L Y + G + +L+L F + G L+ + K TE+ + + L
Sbjct: 115 EVNHPFIVKL-HYAFQTEG---KLYLILDFLRGGDLFTRLS----KEVMFTEEDVKFYLA 166
Query: 131 GICRGLEAIHAKGYAHRDLKPTNILLGDEGQPVLMDLGSMNQACIHVEGSRQALTLQDWA 190
+ L+ +H+ G +RDLKP NILL +EG + D G +A H ++A +
Sbjct: 167 ELALALDHLHSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDH---DKRAYSFCG-- 221
Query: 191 AQRCTISYRAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQKGDSVALAVQ 250
TI Y APE+ + + H + D WS G +++ M+ G P+ +K +++AL ++
Sbjct: 222 ----TIEYMAPEVVNRRGH---TQSADWWSFGVLMFEMLTGSLPFQGKDRK-ETMALILK 273
Query: 251 NQLSIPQ--SPRHSSALRQL 268
+L +PQ S S LR L
Sbjct: 274 AKLGMPQFLSGEAQSLLRAL 293
Score = 68.2 bits (165), Expect = 9e-12
Identities = 73/262 (27%), Positives = 122/262 (46%), Gaps = 43/262 (16%)
Query: 46 YALKRILCHEQQDREEAQREADMHRLFNHPNILRLVAYCLRERGAKHEAWLLLPFFKRGT 105
YA+K I ++ R+ ++ + R HPNI+ L + + G +L++ + G
Sbjct: 441 YAVKII---DKSKRDPSEEIEILLRYGQHPNIITLKD--VYDDGKF--VYLVMELMRGGE 493
Query: 106 LWNEIERLKDKGNFLTEDQILWLLLGICRGLEAIHAKGYAHRDLKPTNILLGDE-GQPVL 164
L + I R + + +E + +L I + ++ +H++G HRDLKP+NIL DE G P
Sbjct: 494 LLDRILRQR----YFSEREASDVLCTITKTMDYLHSQGVVHRDLKPSNILYRDESGSPES 549
Query: 165 MDLGSMNQACIHVEGSRQALTLQDWAAQRCTISYRAPELFSVQSHCVIDERTDVWSLGCV 224
+ + A G+ +T T ++ APE+ Q + D D+WSLG +
Sbjct: 550 IRVCDFGFAKQLRAGNGLLMT------PCYTANFVAPEVLKRQGY---DAACDIWSLGIL 600
Query: 225 LYAMM-----FGEGPYD-----MVFQKGDSVALAVQNQLSIPQSPRHSSALRQLLNSMMT 274
LY M+ F GP D + AL+ N SI S A + +++ M+
Sbjct: 601 LYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSI------SDAAKDVVSKMLH 654
Query: 275 VDPHQRPHIPLLLSQLEALQPP 296
VDPHQR L+ ++ L+ P
Sbjct: 655 VDPHQR------LTAMQVLKHP 670
>gi|83627721 NIMA-related kinase 5 [Homo sapiens]
Length = 708
Score = 92.4 bits (228), Expect = 4e-19
Identities = 80/283 (28%), Positives = 128/283 (45%), Gaps = 27/283 (9%)
Query: 19 RYLFIQKLGEGGFSYVDLVEGLHDGHFYALKRILCHEQ--QDREEAQREADMHRLFNHPN 76
+Y I+ +G+G F L +G D +K I + Q++E +++E + HPN
Sbjct: 3 KYDVIKAIGQGAFGKAYLAKGKSDSKHCVIKEINFEKMPIQEKEASKKEVILLEKMKHPN 62
Query: 77 ILRLVAYCLRERGAKHEAWLLLPFFKRGTLWNEIERLKDKGNFLTEDQILWLLLGICRGL 136
I+ +E G ++++ + G L I R +G +EDQIL + I GL
Sbjct: 63 IVAFFN-SFQENG---RLFIVMEYCDGGDLMKRINR--QRGVLFSEDQILGWFVQISLGL 116
Query: 137 EAIHAKGYAHRDLKPTNILLGDEGQPVLMDLGSMNQACIHVEGSRQALTLQDWAAQRC-- 194
+ IH + HRD+K NI L G ++ LG G + L A+ C
Sbjct: 117 KHIHDRKILHRDIKAQNIFLSKNG--MVAKLGDF--------GIARVLNNSMELARTCIG 166
Query: 195 TISYRAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQKGDSVALAVQNQLS 254
T Y +PE+ + + + +TD+WSLGCVLY + + P++ + L +
Sbjct: 167 TPYYLSPEICQNKPY---NNKTDIWSLGCVLYELCTLKHPFE--GNNLQQLVLKICQAHF 221
Query: 255 IPQSPRHSSALRQLLNSMMTVDPHQRPHIPLLLSQ--LEALQP 295
P SP S L L++ + V P RP I +L + LE L P
Sbjct: 222 APISPGFSRELHSLISQLFQVSPRDRPSINSILKRPFLENLIP 264
>gi|191252782 p21-activated kinase 6 [Homo sapiens]
Length = 681
Score = 92.4 bits (228), Expect = 4e-19
Identities = 80/280 (28%), Positives = 122/280 (43%), Gaps = 33/280 (11%)
Query: 25 KLGEGGFSYVDLVEGLHDGHFYALKRILCHEQQDREEAQREADMHRLFNHPNILRLV-AY 83
K+GEG V L H G A+K + +QQ RE E + R + H N++ + +Y
Sbjct: 412 KIGEGSTGIVCLAREKHSGRQVAVKMMDLRKQQRRELLFNEVVIMRDYQHFNVVEMYKSY 471
Query: 84 CLRERGAKHEAWLLLPFFKRGTLWNEIERLKDKGNFLTEDQILWLLLGICRGLEAIHAKG 143
+ E E W+L+ F + G L + + +++ L E+QI + + + L +HA+G
Sbjct: 472 LVGE-----ELWVLMEFLQGGALTDIVSQVR-----LNEEQIATVCEAVLQALAYLHAQG 521
Query: 144 YAHRDLKPTNILLGDEGQPVLMDLGSMNQACIHVEGSRQALTLQDWAAQRCTISYRAPEL 203
HRD+K +ILL +G+ L D G Q V + + W APE+
Sbjct: 522 VIHRDIKSDSILLTLDGRVKLSDFGFCAQISKDVPKRKSLVGTPYW---------MAPEV 572
Query: 204 FSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQKGDSVALAVQNQLSIP-----QS 258
S + D+WSLG ++ M+ GE PY DS A++ P S
Sbjct: 573 ISRSLYAT---EVDIWSLGIMVIEMVDGEPPY-----FSDSPVQAMKRLRDSPPPKLKNS 624
Query: 259 PRHSSALRQLLNSMMTVDPHQRPHIPLLLSQLEALQPPAP 298
+ S LR L M+ DP +R LL LQ P
Sbjct: 625 HKVSPVLRDFLERMLVRDPQERATAQELLDHPFLLQTGLP 664
>gi|191252780 p21-activated kinase 6 [Homo sapiens]
Length = 681
Score = 92.4 bits (228), Expect = 4e-19
Identities = 80/280 (28%), Positives = 122/280 (43%), Gaps = 33/280 (11%)
Query: 25 KLGEGGFSYVDLVEGLHDGHFYALKRILCHEQQDREEAQREADMHRLFNHPNILRLV-AY 83
K+GEG V L H G A+K + +QQ RE E + R + H N++ + +Y
Sbjct: 412 KIGEGSTGIVCLAREKHSGRQVAVKMMDLRKQQRRELLFNEVVIMRDYQHFNVVEMYKSY 471
Query: 84 CLRERGAKHEAWLLLPFFKRGTLWNEIERLKDKGNFLTEDQILWLLLGICRGLEAIHAKG 143
+ E E W+L+ F + G L + + +++ L E+QI + + + L +HA+G
Sbjct: 472 LVGE-----ELWVLMEFLQGGALTDIVSQVR-----LNEEQIATVCEAVLQALAYLHAQG 521
Query: 144 YAHRDLKPTNILLGDEGQPVLMDLGSMNQACIHVEGSRQALTLQDWAAQRCTISYRAPEL 203
HRD+K +ILL +G+ L D G Q V + + W APE+
Sbjct: 522 VIHRDIKSDSILLTLDGRVKLSDFGFCAQISKDVPKRKSLVGTPYW---------MAPEV 572
Query: 204 FSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQKGDSVALAVQNQLSIP-----QS 258
S + D+WSLG ++ M+ GE PY DS A++ P S
Sbjct: 573 ISRSLYAT---EVDIWSLGIMVIEMVDGEPPY-----FSDSPVQAMKRLRDSPPPKLKNS 624
Query: 259 PRHSSALRQLLNSMMTVDPHQRPHIPLLLSQLEALQPPAP 298
+ S LR L M+ DP +R LL LQ P
Sbjct: 625 HKVSPVLRDFLERMLVRDPQERATAQELLDHPFLLQTGLP 664
>gi|9910476 p21-activated kinase 6 [Homo sapiens]
Length = 681
Score = 92.4 bits (228), Expect = 4e-19
Identities = 80/280 (28%), Positives = 122/280 (43%), Gaps = 33/280 (11%)
Query: 25 KLGEGGFSYVDLVEGLHDGHFYALKRILCHEQQDREEAQREADMHRLFNHPNILRLV-AY 83
K+GEG V L H G A+K + +QQ RE E + R + H N++ + +Y
Sbjct: 412 KIGEGSTGIVCLAREKHSGRQVAVKMMDLRKQQRRELLFNEVVIMRDYQHFNVVEMYKSY 471
Query: 84 CLRERGAKHEAWLLLPFFKRGTLWNEIERLKDKGNFLTEDQILWLLLGICRGLEAIHAKG 143
+ E E W+L+ F + G L + + +++ L E+QI + + + L +HA+G
Sbjct: 472 LVGE-----ELWVLMEFLQGGALTDIVSQVR-----LNEEQIATVCEAVLQALAYLHAQG 521
Query: 144 YAHRDLKPTNILLGDEGQPVLMDLGSMNQACIHVEGSRQALTLQDWAAQRCTISYRAPEL 203
HRD+K +ILL +G+ L D G Q V + + W APE+
Sbjct: 522 VIHRDIKSDSILLTLDGRVKLSDFGFCAQISKDVPKRKSLVGTPYW---------MAPEV 572
Query: 204 FSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQKGDSVALAVQNQLSIP-----QS 258
S + D+WSLG ++ M+ GE PY DS A++ P S
Sbjct: 573 ISRSLYAT---EVDIWSLGIMVIEMVDGEPPY-----FSDSPVQAMKRLRDSPPPKLKNS 624
Query: 259 PRHSSALRQLLNSMMTVDPHQRPHIPLLLSQLEALQPPAP 298
+ S LR L M+ DP +R LL LQ P
Sbjct: 625 HKVSPVLRDFLERMLVRDPQERATAQELLDHPFLLQTGLP 664
>gi|4759050 ribosomal protein S6 kinase, 90kDa, polypeptide 3 [Homo
sapiens]
Length = 740
Score = 91.3 bits (225), Expect = 1e-18
Identities = 75/261 (28%), Positives = 129/261 (49%), Gaps = 30/261 (11%)
Query: 16 DNKRYLFIQKLGEGGFSYVDLVE---GLHDGHFYALKRI--LCHEQQDREEAQREADMHR 70
D ++ ++ LG+G F V LV+ G YA+K + + +DR + E D+
Sbjct: 64 DPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDILV 123
Query: 71 LFNHPNILRLVAYCLRERGAKHEAWLLLPFFKRGTLWNEIERLKDKGNFLTEDQILWLLL 130
NHP I++L Y + G + +L+L F + G L+ + K TE+ + + L
Sbjct: 124 EVNHPFIVKL-HYAFQTEG---KLYLILDFLRGGDLFTRLS----KEVMFTEEDVKFYLA 175
Query: 131 GICRGLEAIHAKGYAHRDLKPTNILLGDEGQPVLMDLGSMNQACIHVEGSRQALTLQDWA 190
+ L+ +H+ G +RDLKP NILL +EG L D G S++++ + A
Sbjct: 176 ELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGL----------SKESIDHEKKA 225
Query: 191 AQRC-TISYRAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQKGDSVALAV 249
C T+ Y APE+ + + H + D WS G +++ M+ G P+ +K +++ + +
Sbjct: 226 YSFCGTVEYMAPEVVNRRGH---TQSADWWSFGVLMFEMLTGTLPFQGKDRK-ETMTMIL 281
Query: 250 QNQLSIPQ--SPRHSSALRQL 268
+ +L +PQ SP S LR L
Sbjct: 282 KAKLGMPQFLSPEAQSLLRML 302
Score = 69.3 bits (168), Expect = 4e-12
Identities = 68/239 (28%), Positives = 106/239 (44%), Gaps = 24/239 (10%)
Query: 55 EQQDREEAQREADMHRLFNHPNILRLVAYCLRERGAKHEAWLLLPFFKRGTLWNEIERLK 114
++ R+ + + R HPNI+ L + + G +++ K G L ++I R K
Sbjct: 454 DKSKRDPTEEIEILLRYGQHPNIITLKD--VYDDGKY--VYVVTELMKGGELLDKILRQK 509
Query: 115 DKGNFLTEDQILWLLLGICRGLEAIHAKGYAHRDLKPTNILLGDE-GQPVLMDLGSMNQA 173
F +E + +L I + +E +HA+G HRDLKP+NIL DE G P + + A
Sbjct: 510 ----FFSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNILYVDESGNPESIRICDFGFA 565
Query: 174 CIHVEGSRQALTLQDWAAQRC-TISYRAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGE 232
+Q C T ++ APE+ Q + D D+WSLG +LY M+ G
Sbjct: 566 -------KQLRAENGLLMTPCYTANFVAPEVLKRQGY---DAACDIWSLGVLLYTMLTGY 615
Query: 233 GPYDMVFQKGDSVALAVQNQLSIPQSPRH----SSALRQLLNSMMTVDPHQRPHIPLLL 287
P+ LA S + S + L++ M+ VDPHQR L+L
Sbjct: 616 TPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDLVSKMLHVDPHQRLTAALVL 674
>gi|19424132 NIMA-related kinase 7 [Homo sapiens]
Length = 302
Score = 91.3 bits (225), Expect = 1e-18
Identities = 76/275 (27%), Positives = 121/275 (44%), Gaps = 42/275 (15%)
Query: 24 QKLGEGGFSYVDLVEGLHDGHFYALKRILCHEQQD---REEAQREADMHRLFNHPNILRL 80
+K+G G FS V L DG ALK++ + D R + +E D+ + NHPN+++
Sbjct: 38 KKIGRGQFSEVYRAACLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKY 97
Query: 81 VAYCLRERGAKHEAWLLLPFFKRGTLWNEIERLKDKGNFLTEDQILWLLLGICRGLEAIH 140
A + + +E ++L G L I+ K + + E + + +C LE +H
Sbjct: 98 YASFIED----NELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCSALEHMH 153
Query: 141 AKGYAHRDLKPTNILLGDEGQPVLMDLG------SMNQACIHVEGSRQALTLQDWAAQRC 194
++ HRD+KP N+ + G L DLG S A + G
Sbjct: 154 SRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVG--------------- 198
Query: 195 TISYRAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQKGDSVAL----AVQ 250
T Y +PE + + ++D+WSLGC+LY M + P+ GD + L
Sbjct: 199 TPYYMSPERIHENGY---NFKSDIWSLGCLLYEMAALQSPF-----YGDKMNLYSLCKKI 250
Query: 251 NQLSIPQSP--RHSSALRQLLNSMMTVDPHQRPHI 283
Q P P +S LRQL+N + DP +RP +
Sbjct: 251 EQCDYPPLPSDHYSEELRQLVNMCINPDPEKRPDV 285
>gi|30039692 NIMA-related kinase 8 [Homo sapiens]
Length = 692
Score = 90.9 bits (224), Expect = 1e-18
Identities = 73/274 (26%), Positives = 135/274 (49%), Gaps = 22/274 (8%)
Query: 18 KRYLFIQKLGEGGFSYVDLVEGLHDGHFYALKRILCHE--QQDREEAQREADMHRLFNHP 75
++Y I+ +G G F V L D +K+I + +++R+ AQ E + +L NHP
Sbjct: 2 EKYERIRVVGRGAFGIVHLCLRKADQKLVIIKQIPVEQMTKEERQAAQNECQVLKLLNHP 61
Query: 76 NILRLVAYCLRERGAKHEAWLLLPFFKRGTLWNEIERLKDKGNFLTEDQILWLLLGICRG 135
N++ L ++ + + + GTL I+ K + L E+ IL + I
Sbjct: 62 NVIEYYENFLEDKALM----IAMEYAPGGTLAEFIQ--KRCNSLLEEETILHFFVQILLA 115
Query: 136 LEAIHAKGYAHRDLKPTNILLGDEGQPVLMDLGSMNQACIHVEGSRQALTLQDWAAQRCT 195
L +H HRDLK NILL + +++ +G + I + +A T+ T
Sbjct: 116 LHHVHTHLILHRDLKTQNILL--DKHRMVVKIGDFGISKI-LSSKSKAYTVVG------T 166
Query: 196 ISYRAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQKGDSVALAVQNQLSI 255
Y +PEL + + ++++D+W+LGCVLY + + ++ ++ L + +
Sbjct: 167 PCYISPELCEGKPY---NQKSDIWALGCVLYELASLKRAFEAA--NLPALVLKIMSGTFA 221
Query: 256 PQSPRHSSALRQLLNSMMTVDPHQRPHIPLLLSQ 289
P S R+S LRQL+ S+++++P QRP + +++Q
Sbjct: 222 PISDRYSPELRQLVLSLLSLEPAQRPPLSHIMAQ 255
>gi|29826329 p21-activated kinase 7 [Homo sapiens]
Length = 719
Score = 89.7 bits (221), Expect = 3e-18
Identities = 83/289 (28%), Positives = 130/289 (44%), Gaps = 32/289 (11%)
Query: 16 DNKRYL--FIQKLGEGGFSYVDLVEGLHDGHFYALKRILCHEQQDREEAQREADMHRLFN 73
D + YL FI K+GEG V + H G A+K++ +QQ RE E + R ++
Sbjct: 444 DPREYLANFI-KIGEGSTGIVCIATEKHTGKQVAVKKMDLRKQQRRELLFNEVVIMRDYH 502
Query: 74 HPNILRLVAYCLRERGAKHEAWLLLPFFKRGTLWNEIERLKDKGNFLTEDQILWLLLGIC 133
H N++ + + L E W+++ F + G L + + + + E+QI + L +
Sbjct: 503 HDNVVDMYSSYL----VGDELWVVMEFLEGGALTDIVTHTR-----MNEEQIATVCLSVL 553
Query: 134 RGLEAIHAKGYAHRDLKPTNILLGDEGQPVLMDLGSMNQACIHVEGSRQALTLQDWAAQR 193
R L +H +G HRD+K +ILL +G+ L D G Q V + + W
Sbjct: 554 RALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKRKSLVGTPYW---- 609
Query: 194 CTISYRAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQKGDSVAL-AVQNQ 252
APE V S D+WSLG ++ M+ GE PY F + A+ +++
Sbjct: 610 -----MAPE---VISRLPYGTEVDIWSLGIMVIEMIDGEPPY---FNEPPLQAMRRIRDS 658
Query: 253 LSIPQSPRH--SSALRQLLNSMMTVDPHQRPHIPLLLSQ--LEALQPPA 297
L H SS LR L+ M+ +P QR LL L+ PP+
Sbjct: 659 LPPRVKDLHKVSSVLRGFLDLMLVREPSQRATAQELLGHPFLKLAGPPS 707
>gi|24308191 p21-activated kinase 7 [Homo sapiens]
Length = 719
Score = 89.7 bits (221), Expect = 3e-18
Identities = 83/289 (28%), Positives = 130/289 (44%), Gaps = 32/289 (11%)
Query: 16 DNKRYL--FIQKLGEGGFSYVDLVEGLHDGHFYALKRILCHEQQDREEAQREADMHRLFN 73
D + YL FI K+GEG V + H G A+K++ +QQ RE E + R ++
Sbjct: 444 DPREYLANFI-KIGEGSTGIVCIATEKHTGKQVAVKKMDLRKQQRRELLFNEVVIMRDYH 502
Query: 74 HPNILRLVAYCLRERGAKHEAWLLLPFFKRGTLWNEIERLKDKGNFLTEDQILWLLLGIC 133
H N++ + + L E W+++ F + G L + + + + E+QI + L +
Sbjct: 503 HDNVVDMYSSYL----VGDELWVVMEFLEGGALTDIVTHTR-----MNEEQIATVCLSVL 553
Query: 134 RGLEAIHAKGYAHRDLKPTNILLGDEGQPVLMDLGSMNQACIHVEGSRQALTLQDWAAQR 193
R L +H +G HRD+K +ILL +G+ L D G Q V + + W
Sbjct: 554 RALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKRKSLVGTPYW---- 609
Query: 194 CTISYRAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQKGDSVAL-AVQNQ 252
APE V S D+WSLG ++ M+ GE PY F + A+ +++
Sbjct: 610 -----MAPE---VISRLPYGTEVDIWSLGIMVIEMIDGEPPY---FNEPPLQAMRRIRDS 658
Query: 253 LSIPQSPRH--SSALRQLLNSMMTVDPHQRPHIPLLLSQ--LEALQPPA 297
L H SS LR L+ M+ +P QR LL L+ PP+
Sbjct: 659 LPPRVKDLHKVSSVLRGFLDLMLVREPSQRATAQELLGHPFLKLAGPPS 707
>gi|222418622 NIMA-related kinase 6 isoform 1 [Homo sapiens]
Length = 347
Score = 89.4 bits (220), Expect = 4e-18
Identities = 72/269 (26%), Positives = 119/269 (44%), Gaps = 30/269 (11%)
Query: 24 QKLGEGGFSYVDLVEGLHDGHFYALKRILCHEQQD---REEAQREADMHRLFNHPNILRL 80
+K+G G FS V L D ALK++ E D R++ +E + + NHPNI++
Sbjct: 83 KKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNIIKY 142
Query: 81 VAYCLRERGAKHEAWLLLPFFKRGTLWNEIERLKDKGNFLTEDQILWLLLGICRGLEAIH 140
+ + + +E ++L G L I+ K + + E + + +C +E +H
Sbjct: 143 LDSFIED----NELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMH 198
Query: 141 AKGYAHRDLKPTNILLGDEGQPVLMDLGSMNQACIHVEGSRQALTLQDWAAQRCTISYRA 200
++ HRD+KP N+ + G L DLG + + T Y +
Sbjct: 199 SRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSETTAAHSLVG---------TPYYMS 249
Query: 201 PELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQKGDSVAL----AVQNQLSIP 256
PE + + ++D+WSLGC+LY M + P+ GD + L Q P
Sbjct: 250 PERIHENGY---NFKSDIWSLGCLLYEMAALQSPF-----YGDKMNLFSLCQKIEQCDYP 301
Query: 257 QSP--RHSSALRQLLNSMMTVDPHQRPHI 283
P +S LR+L++ + DPHQRP I
Sbjct: 302 PLPGEHYSEKLRELVSMCICPDPHQRPDI 330
>gi|19923407 NIMA-related kinase 6 isoform 2 [Homo sapiens]
Length = 313
Score = 89.4 bits (220), Expect = 4e-18
Identities = 72/269 (26%), Positives = 119/269 (44%), Gaps = 30/269 (11%)
Query: 24 QKLGEGGFSYVDLVEGLHDGHFYALKRILCHEQQD---REEAQREADMHRLFNHPNILRL 80
+K+G G FS V L D ALK++ E D R++ +E + + NHPNI++
Sbjct: 49 KKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNIIKY 108
Query: 81 VAYCLRERGAKHEAWLLLPFFKRGTLWNEIERLKDKGNFLTEDQILWLLLGICRGLEAIH 140
+ + + +E ++L G L I+ K + + E + + +C +E +H
Sbjct: 109 LDSFIED----NELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMH 164
Query: 141 AKGYAHRDLKPTNILLGDEGQPVLMDLGSMNQACIHVEGSRQALTLQDWAAQRCTISYRA 200
++ HRD+KP N+ + G L DLG + + T Y +
Sbjct: 165 SRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSETTAAHSLVG---------TPYYMS 215
Query: 201 PELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQKGDSVAL----AVQNQLSIP 256
PE + + ++D+WSLGC+LY M + P+ GD + L Q P
Sbjct: 216 PERIHENGY---NFKSDIWSLGCLLYEMAALQSPF-----YGDKMNLFSLCQKIEQCDYP 267
Query: 257 QSP--RHSSALRQLLNSMMTVDPHQRPHI 283
P +S LR+L++ + DPHQRP I
Sbjct: 268 PLPGEHYSEKLRELVSMCICPDPHQRPDI 296
>gi|225735561 NIMA-related kinase 3 isoform b [Homo sapiens]
Length = 489
Score = 88.6 bits (218), Expect = 6e-18
Identities = 75/275 (27%), Positives = 121/275 (44%), Gaps = 29/275 (10%)
Query: 20 YLFIQKLGEGGFSYVDLVEGLHDGHFYALKRI-LCHEQQDREEAQREADMHRLFNHPNIL 78
Y+ ++ +GEG F LV+ +A+K I L + + +++EA + HPNI+
Sbjct: 4 YMVLRMIGEGSFGRALLVQHESSNQMFAMKEIRLPKSFSNTQNSRKEAVLLAKMKHPNIV 63
Query: 79 RLVAYCLRERGAKHEAWLLLPFFKRGTLWNEIERLKDKGNFLTEDQILWLLLGICRGLEA 138
A+ ++++ + G L +I++ KG ED IL +C G+
Sbjct: 64 AFK----ESFEAEGHLYIVMEYCDGGDLMQKIKQ--QKGKLFPEDMILNWFTQMCLGVNH 117
Query: 139 IHAKGYAHRDLKPTNILLGDEGQPVLMDLGSMNQACIHVEGSRQALTLQDWAAQRCTI-- 196
IH K HRD+K NI L G+ L D GS A L + A CT
Sbjct: 118 IHKKRVLHRDIKSKNIFLTQNGKVKLGDFGS-------------ARLLSNPMAFACTYVG 164
Query: 197 --SYRAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQKGDSVALAVQNQLS 254
Y PE++ + + ++D+WSLGC+LY + + P+ K ++ L V
Sbjct: 165 TPYYVPPEIW---ENLPYNNKSDIWSLGCILYELCTLKHPFQANSWK--NLILKVCQGCI 219
Query: 255 IPQSPRHSSALRQLLNSMMTVDPHQRPHIPLLLSQ 289
P +S L+ L+ M +P RP LLS+
Sbjct: 220 SPLPSHYSYELQFLVKQMFKRNPSHRPSATTLLSR 254
>gi|23510391 NIMA-related kinase 3 isoform a [Homo sapiens]
Length = 506
Score = 88.6 bits (218), Expect = 6e-18
Identities = 75/275 (27%), Positives = 121/275 (44%), Gaps = 29/275 (10%)
Query: 20 YLFIQKLGEGGFSYVDLVEGLHDGHFYALKRI-LCHEQQDREEAQREADMHRLFNHPNIL 78
Y+ ++ +GEG F LV+ +A+K I L + + +++EA + HPNI+
Sbjct: 4 YMVLRMIGEGSFGRALLVQHESSNQMFAMKEIRLPKSFSNTQNSRKEAVLLAKMKHPNIV 63
Query: 79 RLVAYCLRERGAKHEAWLLLPFFKRGTLWNEIERLKDKGNFLTEDQILWLLLGICRGLEA 138
A+ ++++ + G L +I++ KG ED IL +C G+
Sbjct: 64 AFK----ESFEAEGHLYIVMEYCDGGDLMQKIKQ--QKGKLFPEDMILNWFTQMCLGVNH 117
Query: 139 IHAKGYAHRDLKPTNILLGDEGQPVLMDLGSMNQACIHVEGSRQALTLQDWAAQRCTI-- 196
IH K HRD+K NI L G+ L D GS A L + A CT
Sbjct: 118 IHKKRVLHRDIKSKNIFLTQNGKVKLGDFGS-------------ARLLSNPMAFACTYVG 164
Query: 197 --SYRAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQKGDSVALAVQNQLS 254
Y PE++ + + ++D+WSLGC+LY + + P+ K ++ L V
Sbjct: 165 TPYYVPPEIW---ENLPYNNKSDIWSLGCILYELCTLKHPFQANSWK--NLILKVCQGCI 219
Query: 255 IPQSPRHSSALRQLLNSMMTVDPHQRPHIPLLLSQ 289
P +S L+ L+ M +P RP LLS+
Sbjct: 220 SPLPSHYSYELQFLVKQMFKRNPSHRPSATTLLSR 254
>gi|23510393 NIMA-related kinase 3 isoform a [Homo sapiens]
Length = 506
Score = 88.6 bits (218), Expect = 6e-18
Identities = 75/275 (27%), Positives = 121/275 (44%), Gaps = 29/275 (10%)
Query: 20 YLFIQKLGEGGFSYVDLVEGLHDGHFYALKRI-LCHEQQDREEAQREADMHRLFNHPNIL 78
Y+ ++ +GEG F LV+ +A+K I L + + +++EA + HPNI+
Sbjct: 4 YMVLRMIGEGSFGRALLVQHESSNQMFAMKEIRLPKSFSNTQNSRKEAVLLAKMKHPNIV 63
Query: 79 RLVAYCLRERGAKHEAWLLLPFFKRGTLWNEIERLKDKGNFLTEDQILWLLLGICRGLEA 138
A+ ++++ + G L +I++ KG ED IL +C G+
Sbjct: 64 AFK----ESFEAEGHLYIVMEYCDGGDLMQKIKQ--QKGKLFPEDMILNWFTQMCLGVNH 117
Query: 139 IHAKGYAHRDLKPTNILLGDEGQPVLMDLGSMNQACIHVEGSRQALTLQDWAAQRCTI-- 196
IH K HRD+K NI L G+ L D GS A L + A CT
Sbjct: 118 IHKKRVLHRDIKSKNIFLTQNGKVKLGDFGS-------------ARLLSNPMAFACTYVG 164
Query: 197 --SYRAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQKGDSVALAVQNQLS 254
Y PE++ + + ++D+WSLGC+LY + + P+ K ++ L V
Sbjct: 165 TPYYVPPEIW---ENLPYNNKSDIWSLGCILYELCTLKHPFQANSWK--NLILKVCQGCI 219
Query: 255 IPQSPRHSSALRQLLNSMMTVDPHQRPHIPLLLSQ 289
P +S L+ L+ M +P RP LLS+
Sbjct: 220 SPLPSHYSYELQFLVKQMFKRNPSHRPSATTLLSR 254
>gi|93004081 polo-like kinase 2 [Homo sapiens]
Length = 685
Score = 88.2 bits (217), Expect = 8e-18
Identities = 73/282 (25%), Positives = 136/282 (48%), Gaps = 39/282 (13%)
Query: 13 VIID---NKRYLFIQKLGEGGFSYVDLVEGLHDGHFYALKRILCHEQ----QDREEAQRE 65
+I+D KRY + LG+GGF+ + L + YA K I+ H + RE+ +E
Sbjct: 72 IIVDPTTGKRYCRGKVLGKGGFAKCYEMTDLTNNKVYAAK-IIPHSRVAKPHQREKIDKE 130
Query: 66 ADMHRLFNHPNILRLVAYCLRERGAKHEAWLLLPFFKRGTLWNEIERLKDKGNFLTEDQI 125
++HR+ +H ++++ Y K ++LL + R ++ + ++ K LTE ++
Sbjct: 131 IELHRILHHKHVVQFYHYF----EDKENIYILLEYCSRRSMAHILKARK----VLTEPEV 182
Query: 126 LWLLLGICRGLEAIHAKGYAHRDLKPTNILLGDEGQPVLMDLGSMNQACIHVEGSRQALT 185
+ L I GL+ +H + HRDLK N + + + + D G A
Sbjct: 183 RYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGL-------------AAR 229
Query: 186 LQDWAAQRCTI----SYRAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQK 241
L+ +R TI +Y +PE+ + Q H +D+W+LGCV+Y M+ G P++ K
Sbjct: 230 LEPLEHRRRTICGTPNYLSPEVLNKQGHGC---ESDIWALGCVMYTMLLGRPPFETTNLK 286
Query: 242 GDSVALAVQNQLSIPQSPRHSSALRQLLNSMMTVDPHQRPHI 283
++ + + ++P S + + L+ SM++ +P RP +
Sbjct: 287 -ETYRCIREARYTMPSS--LLAPAKHLIASMLSKNPEDRPSL 325
>gi|38327572 serine/threonine protein kinase 6 [Homo sapiens]
Length = 403
Score = 87.8 bits (216), Expect = 1e-17
Identities = 71/264 (26%), Positives = 120/264 (45%), Gaps = 38/264 (14%)
Query: 26 LGEGGFSYVDLVEGLHDGHFYALKRILCHEQQDR----EEAQREADMHRLFNHPNILRLV 81
LG+G F V L ALK +L Q ++ + +RE ++ HPNILRL
Sbjct: 139 LGKGKFGNVYLAREKQSKFILALK-VLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLY 197
Query: 82 AYCLRERGAKHEA---WLLLPFFKRGTLWNEIERLKDKGNFLTEDQILWLLLGICRGLEA 138
Y H+A +L+L + GT++ E+++L E + + + L
Sbjct: 198 GYF-------HDATRVYLILEYAPLGTVYRELQKLSK----FDEQRTATYITELANALSY 246
Query: 139 IHAKGYAHRDLKPTNILLGDEGQPVLMDLGSMNQACIHVEGSRQALTLQDWAAQRCTISY 198
H+K HRD+KP N+LLG G+ + D G +H SR+ T+ Y
Sbjct: 247 CHSKRVIHRDIKPENLLLGSAGELKIADFG----WSVHAPSSRRTTLCG-------TLDY 295
Query: 199 RAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDM-VFQKGDSVALAVQNQLSIPQ 257
PE+ + H DE+ D+WSLG + Y + G+ P++ +Q ++ + + + P
Sbjct: 296 LPPEMIEGRMH---DEKVDLWSLGVLCYEFLVGKPPFEANTYQ--ETYKRISRVEFTFPD 350
Query: 258 SPRHSSALRQLLNSMMTVDPHQRP 281
+ R L++ ++ +P QRP
Sbjct: 351 FV--TEGARDLISRLLKHNPSQRP 372
>gi|38327570 serine/threonine protein kinase 6 [Homo sapiens]
Length = 403
Score = 87.8 bits (216), Expect = 1e-17
Identities = 71/264 (26%), Positives = 120/264 (45%), Gaps = 38/264 (14%)
Query: 26 LGEGGFSYVDLVEGLHDGHFYALKRILCHEQQDR----EEAQREADMHRLFNHPNILRLV 81
LG+G F V L ALK +L Q ++ + +RE ++ HPNILRL
Sbjct: 139 LGKGKFGNVYLAREKQSKFILALK-VLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLY 197
Query: 82 AYCLRERGAKHEA---WLLLPFFKRGTLWNEIERLKDKGNFLTEDQILWLLLGICRGLEA 138
Y H+A +L+L + GT++ E+++L E + + + L
Sbjct: 198 GYF-------HDATRVYLILEYAPLGTVYRELQKLSK----FDEQRTATYITELANALSY 246
Query: 139 IHAKGYAHRDLKPTNILLGDEGQPVLMDLGSMNQACIHVEGSRQALTLQDWAAQRCTISY 198
H+K HRD+KP N+LLG G+ + D G +H SR+ T+ Y
Sbjct: 247 CHSKRVIHRDIKPENLLLGSAGELKIADFG----WSVHAPSSRRTTLCG-------TLDY 295
Query: 199 RAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDM-VFQKGDSVALAVQNQLSIPQ 257
PE+ + H DE+ D+WSLG + Y + G+ P++ +Q ++ + + + P
Sbjct: 296 LPPEMIEGRMH---DEKVDLWSLGVLCYEFLVGKPPFEANTYQ--ETYKRISRVEFTFPD 350
Query: 258 SPRHSSALRQLLNSMMTVDPHQRP 281
+ R L++ ++ +P QRP
Sbjct: 351 FV--TEGARDLISRLLKHNPSQRP 372
>gi|38327568 serine/threonine protein kinase 6 [Homo sapiens]
Length = 403
Score = 87.8 bits (216), Expect = 1e-17
Identities = 71/264 (26%), Positives = 120/264 (45%), Gaps = 38/264 (14%)
Query: 26 LGEGGFSYVDLVEGLHDGHFYALKRILCHEQQDR----EEAQREADMHRLFNHPNILRLV 81
LG+G F V L ALK +L Q ++ + +RE ++ HPNILRL
Sbjct: 139 LGKGKFGNVYLAREKQSKFILALK-VLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLY 197
Query: 82 AYCLRERGAKHEA---WLLLPFFKRGTLWNEIERLKDKGNFLTEDQILWLLLGICRGLEA 138
Y H+A +L+L + GT++ E+++L E + + + L
Sbjct: 198 GYF-------HDATRVYLILEYAPLGTVYRELQKLSK----FDEQRTATYITELANALSY 246
Query: 139 IHAKGYAHRDLKPTNILLGDEGQPVLMDLGSMNQACIHVEGSRQALTLQDWAAQRCTISY 198
H+K HRD+KP N+LLG G+ + D G +H SR+ T+ Y
Sbjct: 247 CHSKRVIHRDIKPENLLLGSAGELKIADFG----WSVHAPSSRRTTLCG-------TLDY 295
Query: 199 RAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDM-VFQKGDSVALAVQNQLSIPQ 257
PE+ + H DE+ D+WSLG + Y + G+ P++ +Q ++ + + + P
Sbjct: 296 LPPEMIEGRMH---DEKVDLWSLGVLCYEFLVGKPPFEANTYQ--ETYKRISRVEFTFPD 350
Query: 258 SPRHSSALRQLLNSMMTVDPHQRP 281
+ R L++ ++ +P QRP
Sbjct: 351 FV--TEGARDLISRLLKHNPSQRP 372
>gi|38327566 serine/threonine protein kinase 6 [Homo sapiens]
Length = 403
Score = 87.8 bits (216), Expect = 1e-17
Identities = 71/264 (26%), Positives = 120/264 (45%), Gaps = 38/264 (14%)
Query: 26 LGEGGFSYVDLVEGLHDGHFYALKRILCHEQQDR----EEAQREADMHRLFNHPNILRLV 81
LG+G F V L ALK +L Q ++ + +RE ++ HPNILRL
Sbjct: 139 LGKGKFGNVYLAREKQSKFILALK-VLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLY 197
Query: 82 AYCLRERGAKHEA---WLLLPFFKRGTLWNEIERLKDKGNFLTEDQILWLLLGICRGLEA 138
Y H+A +L+L + GT++ E+++L E + + + L
Sbjct: 198 GYF-------HDATRVYLILEYAPLGTVYRELQKLSK----FDEQRTATYITELANALSY 246
Query: 139 IHAKGYAHRDLKPTNILLGDEGQPVLMDLGSMNQACIHVEGSRQALTLQDWAAQRCTISY 198
H+K HRD+KP N+LLG G+ + D G +H SR+ T+ Y
Sbjct: 247 CHSKRVIHRDIKPENLLLGSAGELKIADFG----WSVHAPSSRRTTLCG-------TLDY 295
Query: 199 RAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDM-VFQKGDSVALAVQNQLSIPQ 257
PE+ + H DE+ D+WSLG + Y + G+ P++ +Q ++ + + + P
Sbjct: 296 LPPEMIEGRMH---DEKVDLWSLGVLCYEFLVGKPPFEANTYQ--ETYKRISRVEFTFPD 350
Query: 258 SPRHSSALRQLLNSMMTVDPHQRP 281
+ R L++ ++ +P QRP
Sbjct: 351 FV--TEGARDLISRLLKHNPSQRP 372
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.139 0.437
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,646,525
Number of Sequences: 37866
Number of extensions: 558865
Number of successful extensions: 3486
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 626
Number of HSP's successfully gapped in prelim test: 164
Number of HSP's that attempted gapping in prelim test: 1645
Number of HSP's gapped (non-prelim): 909
length of query: 305
length of database: 18,247,518
effective HSP length: 102
effective length of query: 203
effective length of database: 14,385,186
effective search space: 2920192758
effective search space used: 2920192758
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.