Guide to the Human Genome
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Search of human proteins with 5454016

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5454016 retinitis pigmentosa RP1 protein [Homo sapiens]
         (2156 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5454016 retinitis pigmentosa RP1 protein [Homo sapiens]           4312   0.0  
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]             172   2e-42
gi|30181244 doublecortin isoform c [Homo sapiens]                      96   4e-19
gi|30181242 doublecortin isoform b [Homo sapiens]                      96   4e-19
gi|30181240 doublecortin isoform c [Homo sapiens]                      96   4e-19
gi|30181246 doublecortin isoform a [Homo sapiens]                      96   4e-19
gi|156713428 doublecortin-like kinase 2 isoform a [Homo sapiens]       94   1e-18
gi|156713430 doublecortin-like kinase 2 isoform b [Homo sapiens]       94   2e-18
gi|4758128 doublecortin-like kinase 1 [Homo sapiens]                   91   2e-17
gi|117938307 doublecortin domain containing 2 [Homo sapiens]           82   6e-15
gi|150456471 doublecortin domain containing 2B [Homo sapiens]          65   7e-10
gi|239753110 PREDICTED: doublecortin domain-containing protein E...    62   8e-09
gi|239747673 PREDICTED: doublecortin domain-containing protein E...    62   8e-09
gi|239741542 PREDICTED: doublecortin domain-containing protein E...    62   8e-09
gi|71061468 centromere protein E [Homo sapiens]                        41   0.011
gi|125490370 type I hair keratin KA36 [Homo sapiens]                   39   0.055
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    39   0.072
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...    39   0.072
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho...    39   0.072
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho...    39   0.072
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho...    39   0.072
gi|4759082 serum deprivation response protein [Homo sapiens]           38   0.094
gi|151301098 zinc finger, DBF-type containing 2 [Homo sapiens]         37   0.16 
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)...    37   0.21 
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)...    37   0.21 
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)...    37   0.21 
gi|47717112 zinc finger, FYVE domain containing 9 isoform 1 [Hom...    37   0.27 
gi|47717106 zinc finger, FYVE domain containing 9 isoform 3 [Hom...    37   0.27 
gi|6552337 zinc finger, FYVE domain containing 9 isoform 2 [Homo...    37   0.27 
gi|239747116 PREDICTED: hypothetical protein XP_002343915 isofor...    36   0.47 

>gi|5454016 retinitis pigmentosa RP1 protein [Homo sapiens]
          Length = 2156

 Score = 4312 bits (11184), Expect = 0.0
 Identities = 2156/2156 (100%), Positives = 2156/2156 (100%)

Query: 1    MSDTPSTGFSIIHPTSSEGQVPPPRHLSLTHPVVAKRISFYKSGDPQFGGVRVVVNPRSF 60
            MSDTPSTGFSIIHPTSSEGQVPPPRHLSLTHPVVAKRISFYKSGDPQFGGVRVVVNPRSF
Sbjct: 1    MSDTPSTGFSIIHPTSSEGQVPPPRHLSLTHPVVAKRISFYKSGDPQFGGVRVVVNPRSF 60

Query: 61   KSFDALLDNLSRKVPLPFGVRNISTPRGRHSITRLEELEDGESYLCSHGRKVQPVDLDKA 120
            KSFDALLDNLSRKVPLPFGVRNISTPRGRHSITRLEELEDGESYLCSHGRKVQPVDLDKA
Sbjct: 61   KSFDALLDNLSRKVPLPFGVRNISTPRGRHSITRLEELEDGESYLCSHGRKVQPVDLDKA 120

Query: 121  RRRPRPWLSSRAISAHSPPHPVAVAAPGMPRPPRSLVVFRNGDPKTRRAVLLSRRVTQSF 180
            RRRPRPWLSSRAISAHSPPHPVAVAAPGMPRPPRSLVVFRNGDPKTRRAVLLSRRVTQSF
Sbjct: 121  RRRPRPWLSSRAISAHSPPHPVAVAAPGMPRPPRSLVVFRNGDPKTRRAVLLSRRVTQSF 180

Query: 181  EAFLQHLTEVMQRPVVKLYATDGRRVPSLQAVILSSGAVVAAGREPFKPGNYDIQKYLLP 240
            EAFLQHLTEVMQRPVVKLYATDGRRVPSLQAVILSSGAVVAAGREPFKPGNYDIQKYLLP
Sbjct: 181  EAFLQHLTEVMQRPVVKLYATDGRRVPSLQAVILSSGAVVAAGREPFKPGNYDIQKYLLP 240

Query: 241  ARLPGISQRVYPKGNAKSESRKISTHMSSSSRSQIYSVSSEKTHNNDCYLDYSFVPEKYL 300
            ARLPGISQRVYPKGNAKSESRKISTHMSSSSRSQIYSVSSEKTHNNDCYLDYSFVPEKYL
Sbjct: 241  ARLPGISQRVYPKGNAKSESRKISTHMSSSSRSQIYSVSSEKTHNNDCYLDYSFVPEKYL 300

Query: 301  ALEKNDSQNLPIYPSEDDIEKSIIFNQDGTMTVEMKVRFRIKEEETIKWTTTVSKTGPSN 360
            ALEKNDSQNLPIYPSEDDIEKSIIFNQDGTMTVEMKVRFRIKEEETIKWTTTVSKTGPSN
Sbjct: 301  ALEKNDSQNLPIYPSEDDIEKSIIFNQDGTMTVEMKVRFRIKEEETIKWTTTVSKTGPSN 360

Query: 361  NDEKSEMSFPGRTESRSSGLKLAACSFSADVSPMERSSNQEGSLAEEINIQMTDQVAETC 420
            NDEKSEMSFPGRTESRSSGLKLAACSFSADVSPMERSSNQEGSLAEEINIQMTDQVAETC
Sbjct: 361  NDEKSEMSFPGRTESRSSGLKLAACSFSADVSPMERSSNQEGSLAEEINIQMTDQVAETC 420

Query: 421  SSASWENATVDTDIIQGTQDQAKHRFYRPPTPGLRRVRQKKSVIGSVTLVSETEVQEKMI 480
            SSASWENATVDTDIIQGTQDQAKHRFYRPPTPGLRRVRQKKSVIGSVTLVSETEVQEKMI
Sbjct: 421  SSASWENATVDTDIIQGTQDQAKHRFYRPPTPGLRRVRQKKSVIGSVTLVSETEVQEKMI 480

Query: 481  GQFSYSEERESGENKSEYHMFTHSCSKMSSVSNKPVLVQINNNDQMEESSLERKKENSLL 540
            GQFSYSEERESGENKSEYHMFTHSCSKMSSVSNKPVLVQINNNDQMEESSLERKKENSLL
Sbjct: 481  GQFSYSEERESGENKSEYHMFTHSCSKMSSVSNKPVLVQINNNDQMEESSLERKKENSLL 540

Query: 541  KSSAISAGVIEITSQKMLEMSHNNGLPSTISNNSIVEEDVVDCVVLDNKTGIKNFKTYGN 600
            KSSAISAGVIEITSQKMLEMSHNNGLPSTISNNSIVEEDVVDCVVLDNKTGIKNFKTYGN
Sbjct: 541  KSSAISAGVIEITSQKMLEMSHNNGLPSTISNNSIVEEDVVDCVVLDNKTGIKNFKTYGN 600

Query: 601  TNDRFSPISADATHFSSNNSGTDKNISEAPASEASSTVTARIDRLINEFAQCGLTKLPKN 660
            TNDRFSPISADATHFSSNNSGTDKNISEAPASEASSTVTARIDRLINEFAQCGLTKLPKN
Sbjct: 601  TNDRFSPISADATHFSSNNSGTDKNISEAPASEASSTVTARIDRLINEFAQCGLTKLPKN 660

Query: 661  EKKILSSVASKKKKKSRQQAINSRYQDGQLATKGILNKNERINTKGRITKEMIVQDSDSP 720
            EKKILSSVASKKKKKSRQQAINSRYQDGQLATKGILNKNERINTKGRITKEMIVQDSDSP
Sbjct: 661  EKKILSSVASKKKKKSRQQAINSRYQDGQLATKGILNKNERINTKGRITKEMIVQDSDSP 720

Query: 721  LKGGILCEEDLQKSDTVIESNTFCSKSNLNSTISKNFHRNKLNTTQNSKVQGLLTKRKSR 780
            LKGGILCEEDLQKSDTVIESNTFCSKSNLNSTISKNFHRNKLNTTQNSKVQGLLTKRKSR
Sbjct: 721  LKGGILCEEDLQKSDTVIESNTFCSKSNLNSTISKNFHRNKLNTTQNSKVQGLLTKRKSR 780

Query: 781  SLNKISLGAPKKREIGQRDKVFPHNESKYCKSTFENKSLFHVFNILEQKPKDFYAPQSQA 840
            SLNKISLGAPKKREIGQRDKVFPHNESKYCKSTFENKSLFHVFNILEQKPKDFYAPQSQA
Sbjct: 781  SLNKISLGAPKKREIGQRDKVFPHNESKYCKSTFENKSLFHVFNILEQKPKDFYAPQSQA 840

Query: 841  EVASGYLRGMAKKSLVSKVTDSHITLKSQKKRKGDKVKASAILSKQHATTRANSLASLKK 900
            EVASGYLRGMAKKSLVSKVTDSHITLKSQKKRKGDKVKASAILSKQHATTRANSLASLKK
Sbjct: 841  EVASGYLRGMAKKSLVSKVTDSHITLKSQKKRKGDKVKASAILSKQHATTRANSLASLKK 900

Query: 901  PDFPEAIAHHSIQNYIQSWLQNINPYPTLKPIKSAPVCRNETSVVNCSNNSFSGNDPHTN 960
            PDFPEAIAHHSIQNYIQSWLQNINPYPTLKPIKSAPVCRNETSVVNCSNNSFSGNDPHTN
Sbjct: 901  PDFPEAIAHHSIQNYIQSWLQNINPYPTLKPIKSAPVCRNETSVVNCSNNSFSGNDPHTN 960

Query: 961  SGKISNFVMESNKHITKIAGLTGDNLCKEGDKSFIANDTGEEDLHETQVGSLNDAYLVPL 1020
            SGKISNFVMESNKHITKIAGLTGDNLCKEGDKSFIANDTGEEDLHETQVGSLNDAYLVPL
Sbjct: 961  SGKISNFVMESNKHITKIAGLTGDNLCKEGDKSFIANDTGEEDLHETQVGSLNDAYLVPL 1020

Query: 1021 HEHCTLSQSAINDHNTKSHIAAEKSGPEKKLVYQEINLARKRQSVEAAIQVDPIEEETPK 1080
            HEHCTLSQSAINDHNTKSHIAAEKSGPEKKLVYQEINLARKRQSVEAAIQVDPIEEETPK
Sbjct: 1021 HEHCTLSQSAINDHNTKSHIAAEKSGPEKKLVYQEINLARKRQSVEAAIQVDPIEEETPK 1080

Query: 1081 DLLPVLMLHQLQASVPGIHKTQNGVVQMPGSLAGVPFHSAICNSSTNLLLAWLLVLNLKG 1140
            DLLPVLMLHQLQASVPGIHKTQNGVVQMPGSLAGVPFHSAICNSSTNLLLAWLLVLNLKG
Sbjct: 1081 DLLPVLMLHQLQASVPGIHKTQNGVVQMPGSLAGVPFHSAICNSSTNLLLAWLLVLNLKG 1140

Query: 1141 SMNSFCQVDAHKATNKSSETLALLEILKHIAITEEADDLKAAVANLVESTTSHFGLSEKE 1200
            SMNSFCQVDAHKATNKSSETLALLEILKHIAITEEADDLKAAVANLVESTTSHFGLSEKE
Sbjct: 1141 SMNSFCQVDAHKATNKSSETLALLEILKHIAITEEADDLKAAVANLVESTTSHFGLSEKE 1200

Query: 1201 QDMVPIDLSANCSTVNIQSVPKCSENERTQGISSLDGGCSASEACAPEVCVLEVTCSPCE 1260
            QDMVPIDLSANCSTVNIQSVPKCSENERTQGISSLDGGCSASEACAPEVCVLEVTCSPCE
Sbjct: 1201 QDMVPIDLSANCSTVNIQSVPKCSENERTQGISSLDGGCSASEACAPEVCVLEVTCSPCE 1260

Query: 1261 MCTVNKAYSPKETCNPSDTFFPSDGYGVDQTSMNKACFLGEVCSLTDTVFSDKACAQKEN 1320
            MCTVNKAYSPKETCNPSDTFFPSDGYGVDQTSMNKACFLGEVCSLTDTVFSDKACAQKEN
Sbjct: 1261 MCTVNKAYSPKETCNPSDTFFPSDGYGVDQTSMNKACFLGEVCSLTDTVFSDKACAQKEN 1320

Query: 1321 HTYEGACPIDETYVPVNVCNTIDFLNSKENTYTDNLDSTEELERGDDIQKDLNILTDPEY 1380
            HTYEGACPIDETYVPVNVCNTIDFLNSKENTYTDNLDSTEELERGDDIQKDLNILTDPEY
Sbjct: 1321 HTYEGACPIDETYVPVNVCNTIDFLNSKENTYTDNLDSTEELERGDDIQKDLNILTDPEY 1380

Query: 1381 KNGFNTLVSHQNVSNLSSCGLCLSEKEAELDKKHSSLDDFENCSLRKFQDENAYTSFDME 1440
            KNGFNTLVSHQNVSNLSSCGLCLSEKEAELDKKHSSLDDFENCSLRKFQDENAYTSFDME
Sbjct: 1381 KNGFNTLVSHQNVSNLSSCGLCLSEKEAELDKKHSSLDDFENCSLRKFQDENAYTSFDME 1440

Query: 1441 EPRTSEEPGSITNSMTSSERNISELESFEELENHDTDIFNTVVNGGEQATEELIQEEVEA 1500
            EPRTSEEPGSITNSMTSSERNISELESFEELENHDTDIFNTVVNGGEQATEELIQEEVEA
Sbjct: 1441 EPRTSEEPGSITNSMTSSERNISELESFEELENHDTDIFNTVVNGGEQATEELIQEEVEA 1500

Query: 1501 SKTLELIDISSKNIMEEKRMNGIIYEIISKRLATPPSLDFCYDSKQNSEKETNEGETKMV 1560
            SKTLELIDISSKNIMEEKRMNGIIYEIISKRLATPPSLDFCYDSKQNSEKETNEGETKMV
Sbjct: 1501 SKTLELIDISSKNIMEEKRMNGIIYEIISKRLATPPSLDFCYDSKQNSEKETNEGETKMV 1560

Query: 1561 KMMVKTMETGSYSESSPDLKKCIKSPVTSDWSDYRPDSDSEQPYKTSSDDPNDSGELTQE 1620
            KMMVKTMETGSYSESSPDLKKCIKSPVTSDWSDYRPDSDSEQPYKTSSDDPNDSGELTQE
Sbjct: 1561 KMMVKTMETGSYSESSPDLKKCIKSPVTSDWSDYRPDSDSEQPYKTSSDDPNDSGELTQE 1620

Query: 1621 KEYNIGFVKRAIEKLYGKADIIKPSFFPGSTRKSQVCPYNSVEFQCSRKASLYDSEGQSF 1680
            KEYNIGFVKRAIEKLYGKADIIKPSFFPGSTRKSQVCPYNSVEFQCSRKASLYDSEGQSF
Sbjct: 1621 KEYNIGFVKRAIEKLYGKADIIKPSFFPGSTRKSQVCPYNSVEFQCSRKASLYDSEGQSF 1680

Query: 1681 GSSEQVSSSSSMLQEFQEERQDKCDVSAVRDNYCRGDIVEPGTKQNDDSRILTDIEEGVL 1740
            GSSEQVSSSSSMLQEFQEERQDKCDVSAVRDNYCRGDIVEPGTKQNDDSRILTDIEEGVL
Sbjct: 1681 GSSEQVSSSSSMLQEFQEERQDKCDVSAVRDNYCRGDIVEPGTKQNDDSRILTDIEEGVL 1740

Query: 1741 IDKGKWLLKENHLLRMSSENPGMCGNADTTSVDTLLDNNSSEVPYSHFGNLAPGPTMDEL 1800
            IDKGKWLLKENHLLRMSSENPGMCGNADTTSVDTLLDNNSSEVPYSHFGNLAPGPTMDEL
Sbjct: 1741 IDKGKWLLKENHLLRMSSENPGMCGNADTTSVDTLLDNNSSEVPYSHFGNLAPGPTMDEL 1800

Query: 1801 SSSELEELTQPLELKCNYFNMPHGSDSEPFHEDLLDVRNETCAKERIANHHTEEKGSHQS 1860
            SSSELEELTQPLELKCNYFNMPHGSDSEPFHEDLLDVRNETCAKERIANHHTEEKGSHQS
Sbjct: 1801 SSSELEELTQPLELKCNYFNMPHGSDSEPFHEDLLDVRNETCAKERIANHHTEEKGSHQS 1860

Query: 1861 ERVCTSVTHSFISAGNKVYPVSDDAIKNQPLPGSNMIHGTLQEADSLDKLYALCGQHCPI 1920
            ERVCTSVTHSFISAGNKVYPVSDDAIKNQPLPGSNMIHGTLQEADSLDKLYALCGQHCPI
Sbjct: 1861 ERVCTSVTHSFISAGNKVYPVSDDAIKNQPLPGSNMIHGTLQEADSLDKLYALCGQHCPI 1920

Query: 1921 LTVIIQPMNEEDRGFAYRKESDIENFLGFYLWMKIHPYLLQTDKNVFREENNKASMRQNL 1980
            LTVIIQPMNEEDRGFAYRKESDIENFLGFYLWMKIHPYLLQTDKNVFREENNKASMRQNL
Sbjct: 1921 LTVIIQPMNEEDRGFAYRKESDIENFLGFYLWMKIHPYLLQTDKNVFREENNKASMRQNL 1980

Query: 1981 IDNAIGDIFDQFYFSNTFDLMGKRRKQKRINFLGLEEEGNLKKFQPDLKERFCMNFLHTS 2040
            IDNAIGDIFDQFYFSNTFDLMGKRRKQKRINFLGLEEEGNLKKFQPDLKERFCMNFLHTS
Sbjct: 1981 IDNAIGDIFDQFYFSNTFDLMGKRRKQKRINFLGLEEEGNLKKFQPDLKERFCMNFLHTS 2040

Query: 2041 LLVVGNVDSNTQDLSGQTNEIFKAVDENNNLLNNRFQGSRTNLNQVVRENINCHYFFEML 2100
            LLVVGNVDSNTQDLSGQTNEIFKAVDENNNLLNNRFQGSRTNLNQVVRENINCHYFFEML
Sbjct: 2041 LLVVGNVDSNTQDLSGQTNEIFKAVDENNNLLNNRFQGSRTNLNQVVRENINCHYFFEML 2100

Query: 2101 GQACLLDICQVETSLNISNRNILELCMFEGENLFIWEEEDILNLTDLESSREQEDL 2156
            GQACLLDICQVETSLNISNRNILELCMFEGENLFIWEEEDILNLTDLESSREQEDL
Sbjct: 2101 GQACLLDICQVETSLNISNRNILELCMFEGENLFIWEEEDILNLTDLESSREQEDL 2156


>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
          Length = 2400

 Score =  172 bits (437), Expect = 2e-42
 Identities = 107/328 (32%), Positives = 176/328 (53%), Gaps = 8/328 (2%)

Query: 28  SLTHPVVAKRISFYKSGDPQFGGVRVVVNPRSFKSFDALLDNLSRKVPLPFGVRNISTPR 87
           S+T    AK+I+F K GDP+F GVR+ V+ R+FK+F AL+D LS++VPL FGVR+++TPR
Sbjct: 26  SVTKVTPAKKITFLKRGDPRFAGVRLAVHQRAFKTFSALMDELSQRVPLSFGVRSVTTPR 85

Query: 88  GRHSITRLEELEDGESYLCSHGRKVQPVDLDKARRRPRPWLSSRAISAHSPPHPVAVAAP 147
           G HS++ LE+LEDG  YLCS  +  +        +   P              P   ++ 
Sbjct: 86  GLHSLSALEQLEDGGCYLCSDKKPPKTPSGPGRPQERNPTAQQLRDVEGQREAPGTSSSR 145

Query: 148 GMPRPPRSLVVFRNGDPKTRRAVLLSRRVTQSFEAFLQHLTEVMQRPVVKLYATDGRRVP 207
              + PR +++ +N DP+ ++ V+LS R T++  AFL   +++++ PV +LY T G++V 
Sbjct: 146 KSLKTPRRILLIKNMDPRLQQTVVLSHRNTRNLAAFLGKASDLLRFPVKQLYTTSGKKVD 205

Query: 208 SLQAVILSSGAVVAAGREPFKPGNYDIQKYLLPARLPGISQRVYPKGNAKSESRKISTHM 267
           SLQA++ S   +V AG E F+       +      L G++ R   K  +     K S   
Sbjct: 206 SLQALLHSPSVLVCAGHEAFRTPAMKNARRSEAETLSGLTSR--NKNGSWGPKTKPSVIH 263

Query: 268 SSSSRSQIYSVSSEKTHNNDCYLDYSFVPEKYLALEKNDSQNLPIYPSEDDIEKSIIFNQ 327
           S S       +      +N         P      +   +Q+ P+  + DD++K +  N+
Sbjct: 264 SRSPPGSTPRLPERPGPSNP-----PVGPAPGRHPQDTPAQSGPLV-AGDDMKKKVRMNE 317

Query: 328 DGTMTVEMKVRFRIKEEETIKWTTTVSK 355
           DG+++VEMKVRF +  E+T+ W+  + +
Sbjct: 318 DGSLSVEMKVRFHLVGEDTLLWSRRMGR 345


>gi|30181244 doublecortin isoform c [Homo sapiens]
          Length = 360

 Score = 95.9 bits (237), Expect = 4e-19
 Identities = 68/215 (31%), Positives = 108/215 (50%), Gaps = 15/215 (6%)

Query: 28  SLTHPVVAKRISFYKSGDPQFGGVRVVVNPRSFKSFDALLDNLSRK----VPLPFGVRNI 83
           +L++   AK++ FY++GD  F G+   V+   F+SFDALL +L+R     + LP GVR I
Sbjct: 45  ALSNEKKAKKVRFYRNGDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQGVRYI 104

Query: 84  STPRGRHSITRLEELEDGESYLCSHGRKVQPVDLDKARRRPRPWLSSRAISAHSPPHPVA 143
            T  G   I  ++ELE+GESY+CS     + V+  K    P   ++ +  +    P  +A
Sbjct: 105 YTIDGSRKIGSMDELEEGESYVCSSDNFFKKVEYTK-NVNPNWSVNVKTSANMKAPQSLA 163

Query: 144 VAAPGMPRP------PRSLVVFRNG-DPKTRRAVLLSRRVTQSFEAFLQHLTEVMQRP-- 194
            +     R       P+ + + R+G  P+    VLL+++   SFE  L  +TE ++    
Sbjct: 164 SSNSAQARENKDFVRPKLVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETG 223

Query: 195 -VVKLYATDGRRVPSLQAVILSSGAVVAAGREPFK 228
            V KLY  DG++V  L          +A G E F+
Sbjct: 224 VVKKLYTLDGKQVTCLHDFFGDDDVFIACGPEKFR 258


>gi|30181242 doublecortin isoform b [Homo sapiens]
          Length = 365

 Score = 95.9 bits (237), Expect = 4e-19
 Identities = 68/215 (31%), Positives = 108/215 (50%), Gaps = 15/215 (6%)

Query: 28  SLTHPVVAKRISFYKSGDPQFGGVRVVVNPRSFKSFDALLDNLSRK----VPLPFGVRNI 83
           +L++   AK++ FY++GD  F G+   V+   F+SFDALL +L+R     + LP GVR I
Sbjct: 45  ALSNEKKAKKVRFYRNGDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQGVRYI 104

Query: 84  STPRGRHSITRLEELEDGESYLCSHGRKVQPVDLDKARRRPRPWLSSRAISAHSPPHPVA 143
            T  G   I  ++ELE+GESY+CS     + V+  K    P   ++ +  +    P  +A
Sbjct: 105 YTIDGSRKIGSMDELEEGESYVCSSDNFFKKVEYTK-NVNPNWSVNVKTSANMKAPQSLA 163

Query: 144 VAAPGMPRP------PRSLVVFRNG-DPKTRRAVLLSRRVTQSFEAFLQHLTEVMQRP-- 194
            +     R       P+ + + R+G  P+    VLL+++   SFE  L  +TE ++    
Sbjct: 164 SSNSAQARENKDFVRPKLVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETG 223

Query: 195 -VVKLYATDGRRVPSLQAVILSSGAVVAAGREPFK 228
            V KLY  DG++V  L          +A G E F+
Sbjct: 224 VVKKLYTLDGKQVTCLHDFFGDDDVFIACGPEKFR 258


>gi|30181240 doublecortin isoform c [Homo sapiens]
          Length = 360

 Score = 95.9 bits (237), Expect = 4e-19
 Identities = 68/215 (31%), Positives = 108/215 (50%), Gaps = 15/215 (6%)

Query: 28  SLTHPVVAKRISFYKSGDPQFGGVRVVVNPRSFKSFDALLDNLSRK----VPLPFGVRNI 83
           +L++   AK++ FY++GD  F G+   V+   F+SFDALL +L+R     + LP GVR I
Sbjct: 45  ALSNEKKAKKVRFYRNGDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQGVRYI 104

Query: 84  STPRGRHSITRLEELEDGESYLCSHGRKVQPVDLDKARRRPRPWLSSRAISAHSPPHPVA 143
            T  G   I  ++ELE+GESY+CS     + V+  K    P   ++ +  +    P  +A
Sbjct: 105 YTIDGSRKIGSMDELEEGESYVCSSDNFFKKVEYTK-NVNPNWSVNVKTSANMKAPQSLA 163

Query: 144 VAAPGMPRP------PRSLVVFRNG-DPKTRRAVLLSRRVTQSFEAFLQHLTEVMQRP-- 194
            +     R       P+ + + R+G  P+    VLL+++   SFE  L  +TE ++    
Sbjct: 164 SSNSAQARENKDFVRPKLVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETG 223

Query: 195 -VVKLYATDGRRVPSLQAVILSSGAVVAAGREPFK 228
            V KLY  DG++V  L          +A G E F+
Sbjct: 224 VVKKLYTLDGKQVTCLHDFFGDDDVFIACGPEKFR 258


>gi|30181246 doublecortin isoform a [Homo sapiens]
          Length = 441

 Score = 95.9 bits (237), Expect = 4e-19
 Identities = 68/215 (31%), Positives = 108/215 (50%), Gaps = 15/215 (6%)

Query: 28  SLTHPVVAKRISFYKSGDPQFGGVRVVVNPRSFKSFDALLDNLSRK----VPLPFGVRNI 83
           +L++   AK++ FY++GD  F G+   V+   F+SFDALL +L+R     + LP GVR I
Sbjct: 126 ALSNEKKAKKVRFYRNGDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQGVRYI 185

Query: 84  STPRGRHSITRLEELEDGESYLCSHGRKVQPVDLDKARRRPRPWLSSRAISAHSPPHPVA 143
            T  G   I  ++ELE+GESY+CS     + V+  K    P   ++ +  +    P  +A
Sbjct: 186 YTIDGSRKIGSMDELEEGESYVCSSDNFFKKVEYTK-NVNPNWSVNVKTSANMKAPQSLA 244

Query: 144 VAAPGMPRP------PRSLVVFRNG-DPKTRRAVLLSRRVTQSFEAFLQHLTEVMQRP-- 194
            +     R       P+ + + R+G  P+    VLL+++   SFE  L  +TE ++    
Sbjct: 245 SSNSAQARENKDFVRPKLVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETG 304

Query: 195 -VVKLYATDGRRVPSLQAVILSSGAVVAAGREPFK 228
            V KLY  DG++V  L          +A G E F+
Sbjct: 305 VVKKLYTLDGKQVTCLHDFFGDDDVFIACGPEKFR 339


>gi|156713428 doublecortin-like kinase 2 isoform a [Homo sapiens]
          Length = 766

 Score = 94.4 bits (233), Expect = 1e-18
 Identities = 93/344 (27%), Positives = 145/344 (42%), Gaps = 34/344 (9%)

Query: 6   STGFSIIHPTSSEGQVPPPRHLS------------LTHPVVAKRISFYKSGDPQFGGVRV 53
           S+G S        G +P P H +            L+    AK+  FY++GD  F G+  
Sbjct: 30  SSGGSSSSGPKGNGLIPSPAHSAHCSFYRTRTLQALSSEKKAKKARFYRNGDRYFKGLVF 89

Query: 54  VVNPRSFKSFDALLDNLSRK----VPLPFGVRNISTPRGRHSITRLEELEDGESYLCSHG 109
            ++   F+SFDALL  L+R     V LP GVR I T  G   +T L+EL +GESY+C+  
Sbjct: 90  AISSDRFRSFDALLIELTRSLSDNVNLPQGVRTIYTIDGSRKVTSLDELLEGESYVCASN 149

Query: 110 RKVQPVDLDKARRRPRPWL------SSRAISAHSPPHPVAVAAPGMPRPPRSLVVFRNGD 163
              + VD  K    P  W       +SRA++A S        +    +P    V+     
Sbjct: 150 EPFRKVDYTK-NINPN-WSVNIKGGTSRALAAASSVKSEVKESKDFIKPKLVTVIRSGVK 207

Query: 164 PKTRRAVLLSRRVTQSFEAFLQHLTEVMQRP---VVKLYATDGRRVPSLQAVILSSGAVV 220
           P+    +LL+++   SFE  L  +TE ++     V +L   DG++V  LQ         +
Sbjct: 208 PRKAVRILLNKKTAHSFEQVLTDITEAIKLDSGVVKRLCTLDGKQVTCLQDFFGDDDVFI 267

Query: 221 AAGREPFKPGNYDI-----QKYLLPARLPGISQRVYPKGNAKSESR--KISTHMSSSSRS 273
           A G E F+    D      +  +L +     S   Y    +   SR  K    ++ +  S
Sbjct: 268 ACGPEKFRYAQDDFVLDHSECRVLKSSYSRSSAVKYSGSKSPGPSRRSKSPASVNGTPSS 327

Query: 274 QIYSVSSEKTHNNDCYLDYSFVPEKYLALEKNDSQNLPIYPSED 317
           Q+ +  S K+ ++      SF   K ++     S N+   P  D
Sbjct: 328 QLSTPKSTKSSSSSPTSPGSFRGLKQISAHGRSSSNVNGGPELD 371


>gi|156713430 doublecortin-like kinase 2 isoform b [Homo sapiens]
          Length = 765

 Score = 93.6 bits (231), Expect = 2e-18
 Identities = 84/293 (28%), Positives = 128/293 (43%), Gaps = 30/293 (10%)

Query: 6   STGFSIIHPTSSEGQVPPPRHLS------------LTHPVVAKRISFYKSGDPQFGGVRV 53
           S+G S        G +P P H +            L+    AK+  FY++GD  F G+  
Sbjct: 30  SSGGSSSSGPKGNGLIPSPAHSAHCSFYRTRTLQALSSEKKAKKARFYRNGDRYFKGLVF 89

Query: 54  VVNPRSFKSFDALLDNLSRK----VPLPFGVRNISTPRGRHSITRLEELEDGESYLCSHG 109
            ++   F+SFDALL  L+R     V LP GVR I T  G   +T L+EL +GESY+C+  
Sbjct: 90  AISSDRFRSFDALLIELTRSLSDNVNLPQGVRTIYTIDGSRKVTSLDELLEGESYVCASN 149

Query: 110 RKVQPVDLDKARRRPRPWL------SSRAISAHSPPHPVAVAAPGMPRPPRSLVVFRNGD 163
              + VD  K    P  W       +SRA++A S        +    +P    V+     
Sbjct: 150 EPFRKVDYTK-NINPN-WSVNIKGGTSRALAAASSVKSEVKESKDFIKPKLVTVIRSGVK 207

Query: 164 PKTRRAVLLSRRVTQSFEAFLQHLTEVMQRP---VVKLYATDGRRVPSLQAVILSSGAVV 220
           P+    +LL+++   SFE  L  +TE ++     V +L   DG++V  LQ         +
Sbjct: 208 PRKAVRILLNKKTAHSFEQVLTDITEAIKLDSGVVKRLCTLDGKQVTCLQDFFGDDDVFI 267

Query: 221 AAGREPFKPGNYDIQKYLLPARLPGISQRVYPKGNAKSESRKISTHMSSSSRS 273
           A G E F+   Y    ++L      + +  Y + +A   S   S   S  S+S
Sbjct: 268 ACGPEKFR---YAQDDFVLDHSECRVLKSSYSRSSAVKYSGSKSPGPSRRSKS 317


>gi|4758128 doublecortin-like kinase 1 [Homo sapiens]
          Length = 729

 Score = 90.5 bits (223), Expect = 2e-17
 Identities = 95/389 (24%), Positives = 157/389 (40%), Gaps = 45/389 (11%)

Query: 35  AKRISFYKSGDPQFGGVRVVVNPRSFKSFDALLDNLSR----KVPLPFGVRNISTPRGRH 90
           AK++ FY++GD  F G+   ++P  F+SF+ALL +L+R     V LP GVR I T  G  
Sbjct: 56  AKKVRFYRNGDRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGVRTIYTIDGLK 115

Query: 91  SITRLEELEDGESYLCSHGRKVQPVDLDKARRRPRP-WLSSRAISAHSPPHPVAVAAPGM 149
            I+ L++L +GESY+C     ++P    +  +   P W  +   ++ S        A G 
Sbjct: 116 KISSLDQLVEGESYVCG---SIEPFKKLEYTKNVNPNWSVNVKTTSASRAVSSLATAKGS 172

Query: 150 PRP---------PRSLVVFRNG-DPKTRRAVLLSRRVTQSFEAFLQHLTEVMQRP---VV 196
           P           P+ + + R+G  P+    +LL+++   SFE  L  +T+ ++     V 
Sbjct: 173 PSEVRENKDFIRPKLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVK 232

Query: 197 KLYATDGRRVPSLQAVILSSGAVVAAGREPFKPGNYDIQKYLLPARLPGISQRVYPKGNA 256
           +LY  DG++V  LQ         +A G E F+   Y     L  +    +    Y K   
Sbjct: 233 RLYTLDGKQVMCLQDFFGDDDIFIACGPEKFR---YQDDFLLDESECRVVKSTSYTK--I 287

Query: 257 KSESRKISTHMSSSSRSQIYSVSSEKTHNNDCYLDYSFVPEKYLALEKNDSQNLPIYPSE 316
            S SR+ +T     SR      S+   +           P   L+  ++     P   S 
Sbjct: 288 ASSSRRSTTKSPGPSRRSKSPASTSSVNG---------TPGSQLSTPRSGKSPSPSPTSP 338

Query: 317 DDIEKSIIFNQDGTMTVEMKVRFRIKEEETIKWTTTVSKTGPSNNDEKSEMSFPGR-TES 375
             + K       G+ T     +     +E           GP     +     P   TE 
Sbjct: 339 GSLRKQRSSQHGGSSTSLASTKVCSSMDE---------NDGPGEEVSEEGFQIPATITER 389

Query: 376 RSSGLKLAACSFSADVSPMERSSNQEGSL 404
              G  +   +F+     +ERS+ +E +L
Sbjct: 390 YKVGRTIGDGNFAVVKECVERSTAREYAL 418


>gi|117938307 doublecortin domain containing 2 [Homo sapiens]
          Length = 476

 Score = 82.0 bits (201), Expect = 6e-15
 Identities = 63/214 (29%), Positives = 110/214 (51%), Gaps = 14/214 (6%)

Query: 25  RHLSLTHPVVAKRISFYKSGDPQFGGVRVVVNPRSFKSFDALLDNLSRKVPLPFG-VRNI 83
           R   L+ PVV K +  Y++GDP + G RVV++ +   SF+  L  ++  V  PFG VRNI
Sbjct: 7   RSSHLSQPVV-KSVLVYRNGDPFYAGRRVVIHEKKVSSFEVFLKEVTGGVQAPFGAVRNI 65

Query: 84  STPRGRHSITRLEELEDGESYLCSHG---RKVQPVDLDKARRRPRPWLSSRAISAHSPPH 140
            TPR  H I +L++++ G +Y+       +K+  +D+ + ++RP   +++          
Sbjct: 66  YTPRTGHRIRKLDQIQSGGNYVAGGQEAFKKLNYLDIGEIKKRPMEVVNTEVKPVIHSRI 125

Query: 141 PVAVAAPGMPRPPRSLVVFRNGD---PKTRRAVLLSRRVTQSFEAFLQHLTE---VMQRP 194
            V+       + P ++ +  NGD   P +R  +L+ R+    ++  LQ +TE   +    
Sbjct: 126 NVSARFRKPLQEPCTIFLIANGDLINPASR--LLIPRKTLNQWDHVLQMVTEKITLRSGA 183

Query: 195 VVKLYATDGRRVPSLQAVILSSGAVVAAGREPFK 228
           V +LY  +G+ V S  A + +    VA GR+ FK
Sbjct: 184 VHRLYTLEGKLVES-GAELENGQFYVAVGRDKFK 216


>gi|150456471 doublecortin domain containing 2B [Homo sapiens]
          Length = 349

 Score = 65.1 bits (157), Expect = 7e-10
 Identities = 61/207 (29%), Positives = 96/207 (46%), Gaps = 21/207 (10%)

Query: 35  AKRISFYKSGDPQFGGVRVVVNPRSFKSFDALLDNLSRKVPLPFGVRNISTPRGRHSITR 94
           AKR+  Y++GDP F G ++VV  R F + +A L  ++  V  P  VR + TP   H +T 
Sbjct: 8   AKRVVVYRNGDPFFPGSQLVVTQRRFPTMEAFLCEVTSAVQAPLAVRALYTPCHGHPVTN 67

Query: 95  LEELEDGESYLCSHGRKVQPVDLDKARRRPRPWLSSRAISAHSPP--HPVAVAAPGMPRP 152
           L +L++   Y+ +   +   +     R +     S R      PP    +   A G   P
Sbjct: 68  LADLKNRGQYVAAGFERFHKLHYLPHRGKDPGGKSCR---LQGPPVTRHLCDGAIGRQLP 124

Query: 153 ---PRSLVVFRNGD-PKTRRAVLLSRRVTQSFEAFLQHLTEVMQRPVVKLYATDGRRVPS 208
              P  + VFRNGD      ++ LS+  +Q +E  L+ LTE      VKL +    ++ +
Sbjct: 125 AGAPSYIHVFRNGDLVSPPFSLKLSQAASQDWETVLKLLTE-----KVKLQSGAVCKLCT 179

Query: 209 LQAVILSSGA-------VVAAGREPFK 228
           L+ + LS+G         VA G + FK
Sbjct: 180 LEGLPLSAGKELVTGHYYVAVGEDEFK 206


>gi|239753110 PREDICTED: doublecortin domain-containing protein
           ENSP00000382097-like [Homo sapiens]
          Length = 530

 Score = 61.6 bits (148), Expect = 8e-09
 Identities = 41/132 (31%), Positives = 65/132 (49%), Gaps = 6/132 (4%)

Query: 35  AKRISFYKSGDPQFGGVRVVVNPRSFKSFDALLDNLSRKVPLPFGVRNISTPRGRHSITR 94
           AK I  Y++GDP + G + V++ R   +F+ALL+ L+ +V +PFGVR + TP   H +  
Sbjct: 85  AKTIVVYRNGDPFYVGKKFVLSRRRAATFEALLEQLTEQVDVPFGVRRLFTPTRGHRVLG 144

Query: 95  LEELEDGESYLCSHGRKVQPVDLDKARRRPRPWLSSRAISAHSPPHPVAVAAPG----MP 150
           L+ L+ G  Y+ +   + +  +LD     PR     R +    P     +  P       
Sbjct: 145 LDALQAGGKYVAAGRERFK--ELDYIHIVPRKPAKIRKLKEIKPVVHCDINVPSKWQTYH 202

Query: 151 RPPRSLVVFRNG 162
           R  R + VF NG
Sbjct: 203 RISRHINVFTNG 214



 Score = 56.6 bits (135), Expect = 3e-07
 Identities = 40/92 (43%), Positives = 55/92 (59%), Gaps = 5/92 (5%)

Query: 145 AAPGMPRPPRSLVVFRNGDP-KTRRAVLLSRRVTQSFEAFLQHLTEVMQRP--VVKLYA- 200
           +AP    P +++VV+RNGDP    +  +LSRR   +FEA L+ LTE +  P  V +L+  
Sbjct: 77  SAPVDTTPAKTIVVYRNGDPFYVGKKFVLSRRRAATFEALLEQLTEQVDVPFGVRRLFTP 136

Query: 201 TDGRRVPSLQAVILSSGAVVAAGREPFKPGNY 232
           T G RV  L A + + G  VAAGRE FK  +Y
Sbjct: 137 TRGHRVLGLDA-LQAGGKYVAAGRERFKELDY 167


>gi|239747673 PREDICTED: doublecortin domain-containing protein
           ENSP00000382097-like [Homo sapiens]
          Length = 714

 Score = 61.6 bits (148), Expect = 8e-09
 Identities = 41/132 (31%), Positives = 65/132 (49%), Gaps = 6/132 (4%)

Query: 35  AKRISFYKSGDPQFGGVRVVVNPRSFKSFDALLDNLSRKVPLPFGVRNISTPRGRHSITR 94
           AK I  Y++GDP + G + V++ R   +F+ALL+ L+ +V +PFGVR + TP   H +  
Sbjct: 191 AKTIVVYRNGDPFYVGKKFVLSRRRAATFEALLEQLTEQVDVPFGVRRLFTPTRGHRVLG 250

Query: 95  LEELEDGESYLCSHGRKVQPVDLDKARRRPRPWLSSRAISAHSPPHPVAVAAPG----MP 150
           L+ L+ G  Y+ +   + +  +LD     PR     R +    P     +  P       
Sbjct: 251 LDALQAGGKYVAAGRERFK--ELDYIHIVPRKPAKIRKLKEIKPVVHCDINVPSKWQTYH 308

Query: 151 RPPRSLVVFRNG 162
           R  R + VF NG
Sbjct: 309 RISRHINVFTNG 320



 Score = 56.6 bits (135), Expect = 3e-07
 Identities = 40/92 (43%), Positives = 55/92 (59%), Gaps = 5/92 (5%)

Query: 145 AAPGMPRPPRSLVVFRNGDP-KTRRAVLLSRRVTQSFEAFLQHLTEVMQRP--VVKLYA- 200
           +AP    P +++VV+RNGDP    +  +LSRR   +FEA L+ LTE +  P  V +L+  
Sbjct: 183 SAPVDTTPAKTIVVYRNGDPFYVGKKFVLSRRRAATFEALLEQLTEQVDVPFGVRRLFTP 242

Query: 201 TDGRRVPSLQAVILSSGAVVAAGREPFKPGNY 232
           T G RV  L A + + G  VAAGRE FK  +Y
Sbjct: 243 TRGHRVLGLDA-LQAGGKYVAAGRERFKELDY 273


>gi|239741542 PREDICTED: doublecortin domain-containing protein
           ENSP00000382097-like [Homo sapiens]
          Length = 510

 Score = 61.6 bits (148), Expect = 8e-09
 Identities = 41/132 (31%), Positives = 65/132 (49%), Gaps = 6/132 (4%)

Query: 35  AKRISFYKSGDPQFGGVRVVVNPRSFKSFDALLDNLSRKVPLPFGVRNISTPRGRHSITR 94
           AK I  Y++GDP + G + V++ R   +F+ALL+ L+ +V +PFGVR + TP   H +  
Sbjct: 191 AKTIVVYRNGDPFYVGKKFVLSRRRAATFEALLEQLTEQVDVPFGVRRLFTPTRGHRVLG 250

Query: 95  LEELEDGESYLCSHGRKVQPVDLDKARRRPRPWLSSRAISAHSPPHPVAVAAPG----MP 150
           L+ L+ G  Y+ +   + +  +LD     PR     R +    P     +  P       
Sbjct: 251 LDALQAGGKYVAAGRERFK--ELDYIHIVPRKPAKIRKLKEIKPVVHCDINVPSKWQTYH 308

Query: 151 RPPRSLVVFRNG 162
           R  R + VF NG
Sbjct: 309 RISRHINVFTNG 320



 Score = 56.6 bits (135), Expect = 3e-07
 Identities = 40/92 (43%), Positives = 55/92 (59%), Gaps = 5/92 (5%)

Query: 145 AAPGMPRPPRSLVVFRNGDP-KTRRAVLLSRRVTQSFEAFLQHLTEVMQRP--VVKLYA- 200
           +AP    P +++VV+RNGDP    +  +LSRR   +FEA L+ LTE +  P  V +L+  
Sbjct: 183 SAPVDTTPAKTIVVYRNGDPFYVGKKFVLSRRRAATFEALLEQLTEQVDVPFGVRRLFTP 242

Query: 201 TDGRRVPSLQAVILSSGAVVAAGREPFKPGNY 232
           T G RV  L A + + G  VAAGRE FK  +Y
Sbjct: 243 TRGHRVLGLDA-LQAGGKYVAAGRERFKELDY 273


>gi|71061468 centromere protein E [Homo sapiens]
          Length = 2701

 Score = 41.2 bits (95), Expect = 0.011
 Identities = 47/216 (21%), Positives = 99/216 (45%), Gaps = 24/216 (11%)

Query: 631  ASEASSTVTARIDRL--INEFAQCGLTKLPKNEKKILSSVASKKKKKSRQQAINSRYQDG 688
            + E   ++T   D L  I E  +    +L ++ ++ L+ +   + K+  +Q++N + +D 
Sbjct: 1340 SQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQ--EQSLNMKEKDN 1397

Query: 689  QLATKGILNKNERINTKG----RITKEMI-----VQDSDSPLKGGILCEEDLQKSDTVIE 739
            +  T  I+++ E+   K     RI  EM+     +Q+S   +K     ++DLQ+   V++
Sbjct: 1398 E--TTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQ 1455

Query: 740  SNTFCSKSNLNSTISKNFHRNKLNTTQNSKVQGLLTKRKSRSLNKISLG-APKKREIGQR 798
            S +   K N+   ++K+     L T +  KV     K +  ++N++ +  + K+ EI   
Sbjct: 1456 SESDQLKENIKEIVAKH-----LETEEELKVAHCCLKEQEETINELRVNLSEKETEISTI 1510

Query: 799  DKVFPHNESKY---CKSTFENKSLFHVFNILEQKPK 831
             K       K     +  +E +  F++  I E + K
Sbjct: 1511 QKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEK 1546



 Score = 34.3 bits (77), Expect = 1.4
 Identities = 81/439 (18%), Positives = 172/439 (39%), Gaps = 33/439 (7%)

Query: 372 RTESRSSGLKLAACSFSADVSPMERSS--NQEGSLAEEI-NIQMTDQVAETCSSASWENA 428
           RTE     LKL   +   +   +ER +  +QE  L  EI N++   + AE  +       
Sbjct: 518 RTEKEEMELKLKEKNDLDEFEALERKTKKDQEMQLIHEISNLKNLVKHAEVYNQDLENEL 577

Query: 429 TVDTDIIQGTQDQAKHRFYRPPTPGLRRVRQKKSVIGSVTLVSETEVQEKMIGQ---FSY 485
           +   ++++  +DQ K       +  L  ++   S   S+  + + +  ++ +      + 
Sbjct: 578 SSKVELLREKEDQIKKLQEYIDSQKLENIKMDLSY--SLESIEDPKQMKQTLFDAETVAL 635

Query: 486 SEERESGENKSEYHMFTHSCSKMSSVSNKPVLVQINNNDQMEESSLERKKENSLLKSSAI 545
             +RES   +SE         ++++        Q+ N+ Q+ +S LE KK+  +     +
Sbjct: 636 DAKRESAFLRSENLELKEKMKELATTYK-----QMENDIQLYQSQLEAKKKMQVDLEKEL 690

Query: 546 SAGVIEITSQKMLEMSHNNGLPSTISNNSIVEEDVVDCVVLDNKTGIKNFKTYGNTNDRF 605
            +   EIT    L    +  +P  +  N  +E  + D     NK   +N           
Sbjct: 691 QSAFNEITKLTSLI---DGKVPKDLLCNLELEGKITDLQKELNKEVEENEALREEVI--- 744

Query: 606 SPISADATHFSSNNSGTDKNISEAPASEASSTVTARIDRLINEFA------QCGLTKLPK 659
             + ++     S      K I +   SE    +T+  D+L +E        Q  L ++ K
Sbjct: 745 --LLSELKSLPSEVERLRKEIQDK--SEELHIITSEKDKLFSEVVHKESRVQGLLEEIGK 800

Query: 660 NEKKILSSVASKKKKKSRQQAINSRYQDGQLATKGILNKNERINTK-GRITKEMIVQDSD 718
            +  + ++ ++ K      Q   + + D +   K +L +NER+N +   ++KE   Q  D
Sbjct: 801 TKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKE--AQKFD 858

Query: 719 SPLKGGILCEEDLQKSDTVIESNTFCSKSNLNSTISKNFHRNKLNTTQNSKVQGLLTKRK 778
           S L G +  E   +  +   ++     + N    + +             + + L+T++ 
Sbjct: 859 SSL-GALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKL 917

Query: 779 SRSLNKISLGAPKKREIGQ 797
            ++L ++     +K ++ Q
Sbjct: 918 QQTLEEVKTLTQEKDDLKQ 936


>gi|125490370 type I hair keratin KA36 [Homo sapiens]
          Length = 431

 Score = 38.9 bits (89), Expect = 0.055
 Identities = 50/194 (25%), Positives = 75/194 (38%), Gaps = 32/194 (16%)

Query: 1239 CSASEACAPEVCVLEVTCSPCEMCTVNKAYSPKETCNPSDTFFPSDGYGVDQTSMNKACF 1298
            CS++  C+PE C     C+P   C+V  A  P  TC  S    PS              F
Sbjct: 5    CSSTH-CSPESCGTASGCAPASSCSVETACLP-GTCATSRCQTPS--------------F 48

Query: 1299 LGEVCSLTDTVFSDKACAQKENHTYEGACP-IDETYVPVNVCNTIDFLNSKENTYTDNLD 1357
            L     LT  +          +    G C   ++     N   T+ FLN +  +Y + + 
Sbjct: 49   LSRSRGLTGCLLPCYFTGSCNSPCLVGNCAWCEDGVFTSNEKETMQFLNDRLASYLEKVR 108

Query: 1358 STE----ELERGDDIQKDLNI-LTDPEYKNGFNTLVSHQNVSNLSSCGLCL----SEKEA 1408
            S E    ELE     Q + +I +  P+Y+  FNT      + +L    LC     S    
Sbjct: 109  SLEETNAELESRIQEQCEQDIPMVCPDYQRYFNT------IEDLQQKILCTKAENSRLAV 162

Query: 1409 ELDKKHSSLDDFEN 1422
            +LD    + DDF++
Sbjct: 163  QLDNCKLATDDFKS 176


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 38.5 bits (88), Expect = 0.072
 Identities = 67/394 (17%), Positives = 139/394 (35%), Gaps = 18/394 (4%)

Query: 1346 NSKENTYTDNLDSTEELERGDDIQKDLNILTDPEYKNGFNTLVSHQNVSNLSSCGLCLSE 1405
            +S  +  +D+ DS++  +   D  K  +  +D + K+  +   S  +  N  S     S 
Sbjct: 604  SSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSS 663

Query: 1406 KEAELDKKHSSLD-----DFENCSLRKFQDENAYTSFDMEEPRTSEEPGSITNSMTSSER 1460
              ++      S D     D  N S      +++ +S   +   +S+   S  +S  SS  
Sbjct: 664  NSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSS--DSSDSSNS 721

Query: 1461 NISELESFEELENHDTDIFNTVVNGGEQATEELIQEEVEASKTLELIDISSKNIMEEKRM 1520
            N S+ +S    ++ D+   +   +  + +      +  ++S + +  D S  +   +   
Sbjct: 722  NSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN 781

Query: 1521 NGIIYEIISKRLATPPSLDFCYDSKQNSEKETNEGETKMVKMMVKTMETGSYSESSPDLK 1580
            +    +  +   ++        DS  +S+   +   +             S S +S D  
Sbjct: 782  SSDSNDSSNSSDSS--------DSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSS 833

Query: 1581 KCIKSPVTSDWSDYRPDSDSEQPYKTSSDDPNDSGELTQEKEYNIGFVKRAIEKLYGKAD 1640
                S  +SD SD    SDS+   ++ S + +DS + +     +         +    +D
Sbjct: 834  DSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSD 893

Query: 1641 IIKPSFFPGSTRKSQVCPYNSVEFQCSRKASLYDSEGQSFGSSEQVSSSSSMLQEFQEER 1700
                S    S+        NS +   S  +S       S  +S    SS+S       + 
Sbjct: 894  SSDSS---NSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDS 950

Query: 1701 QDKCDVSAVRDNYCRGDIVEPGTKQNDDSRILTD 1734
             +  D S   D+    D  +  +  + DS   +D
Sbjct: 951  SNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSD 984



 Score = 38.1 bits (87), Expect = 0.094
 Identities = 71/428 (16%), Positives = 159/428 (37%), Gaps = 14/428 (3%)

Query: 1189 STTSHFGLSEKEQDMVPIDLSANCSTVNIQSVPKCSENERTQGISSLDGGCSASEACAPE 1248
            S +S    S    D    + S+N S  +  S    S+++ +   +S D   S++ + + E
Sbjct: 868  SDSSDSSNSSDSSDSSDSNESSNSSDSSDSS--NSSDSDSSDSSNSSDSSDSSNSSDSSE 925

Query: 1249 VCVLEVTCSPCEMCTVNKAYSPKETCNPSDTFFPSDGYGVDQTSMNKACFLGEVCSLTDT 1308
                    +  +    + +    ++ N SD+   SD      +S + +    +  + +D+
Sbjct: 926  SSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDS 985

Query: 1309 VFSDKACAQKENHTYEGACPIDETYVPVNVCNTIDFLNSKENTYT-DNLDSTEELERGDD 1367
              S  +    ++     +    ++    +  N+ D  NS +++ + D+ DS++  +  D 
Sbjct: 986  SDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDS 1045

Query: 1368 IQKDLNILTDPEYKNGFNTLVSHQNVSNLSSCGLCLSEKEAELDKKHSSLDDFENCSLRK 1427
                 +  +     +  ++  S  + S+ SS     SE     D  +SS     + S   
Sbjct: 1046 SDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDS 1105

Query: 1428 FQDENAYTSFDMEEPRTSEEPGSITNSMTSSERNISELESFEELENHDTDIFNTVVNGGE 1487
                ++  S D  +   S +    ++S  SS+ + S  +S +  E+ D+   +   +  +
Sbjct: 1106 SDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSS-DSSDSSESSDSSDSSDSSDSSD 1164

Query: 1488 QATEELIQEEVEASKTLELIDISSKNIMEEKRMNGIIYEIISKRLATPPSLDFCYDSKQN 1547
             +      +  ++S + +  D S  +   +           S    +  S D    S  +
Sbjct: 1165 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSDS----------SDSSDSSDSSDSSDSSDSS 1214

Query: 1548 SEKETNEGETKMVKMMVKTMETGSYSESSPDLKKCIKSPVTSDWSDYRPDSDSEQPYKTS 1607
               ++++                S S  S D      S  +SD SD   DS+ E   ++ 
Sbjct: 1215 DSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSK 1274

Query: 1608 SDDPNDSG 1615
            S + N++G
Sbjct: 1275 SGNGNNNG 1282



 Score = 34.3 bits (77), Expect = 1.4
 Identities = 67/383 (17%), Positives = 137/383 (35%), Gaps = 31/383 (8%)

Query: 255  NAKSESRKISTHMSSSSRSQIYSVSSEKTHNNDCYLDYSFVPEKYLALEKNDSQNLPIYP 314
            N+ S     S++ S SS S   S SS  + +++   D S   +   + E +DS +     
Sbjct: 653  NSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSS-DSSDSSDSSNSSESSDSSDSSDSD 711

Query: 315  SEDDIEKSIIFNQDGTMTVEMKVRFRIKEEETIKWTTTVSKTGPSNNDEKSEMSFPGRTE 374
            S D  + S   + D   +                   +   +  SN+ + S+ S    + 
Sbjct: 712  SSDSSDSSNSNSSDSDSS------------------NSSDSSDSSNSSDSSDSSDSSNSS 753

Query: 375  SRSSGLKLAACSFSADVSPMERSSNQEGSLAEEINIQMTDQVAETCSSASWENATVDTDI 434
              S     +  S S+D S    SS+   S     +   +D  +++ +S+   N++  +D 
Sbjct: 754  DSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDS-SDSSNSSDSSNSSDSSDS 812

Query: 435  IQGTQDQAKHRFYRPPTPGLRRVRQKKSVIGSVTLVSETEVQEKMIGQFSYSEERESGEN 494
               +   + +                     S      ++  +   G  S S  R    N
Sbjct: 813  SDSSDSDSSNS---------SDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSN 863

Query: 495  KSEYHMFTHSCSKMSSVSNKPVLVQINNNDQMEESSLERKKENSLLKSSAISAGVIEITS 554
             S+    + S +   S  +       N++D  + S+      +    SS  S       S
Sbjct: 864  SSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDS 923

Query: 555  QKMLEMSHNNGLPSTISNNSIVEEDVVDCVVLDNKTGIKNFKTYGNTNDRFSPISADATH 614
             +    S N+   S+ S+NS    D  D     + +   +     +++D  S  S+D+++
Sbjct: 924  SESSNSSDNSN--SSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSN 981

Query: 615  FSSNNSGTDKNISEAPASEASST 637
             S ++  +D + S   +  ++S+
Sbjct: 982  SSDSSDSSDSSDSSDSSDSSNSS 1004



 Score = 32.3 bits (72), Expect = 5.2
 Identities = 67/368 (18%), Positives = 126/368 (34%), Gaps = 9/368 (2%)

Query: 1346 NSKENTYTDNLDSTEELERGDDIQKDLNILTDPEYKNGFNTLVSHQNVSNLSSCGLCLSE 1405
            NS ++  +++ DS++     D      +  +     +  ++  S  + S+ SS     S 
Sbjct: 722  NSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN 781

Query: 1406 KEAELDKKHSSLDDFENCSLRKFQDENAYTSFDMEEPRTSEEPGSITNSMTSSERNISEL 1465
                 D  +SS     + S       ++  S D  +  +S    S  +S +S   N S+ 
Sbjct: 782  SSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDS 841

Query: 1466 -ESFEELENHDTDIFNTVVNGGEQATEELIQEEVEASKTLELIDISSKNIMEEKRMNGII 1524
             +S +  +  D+D  N      + +      +  ++S + +  D S  N  E    +   
Sbjct: 842  SDSSDSSDGSDSDSSNR----SDSSNSSDSSDSSDSSNSSDSSDSSDSN--ESSNSSDSS 895

Query: 1525 YEIISKRLATPPSLDFCYDSKQNSEKETNEGETKMVKMMVKTMETGSYSESSPDLKKCIK 1584
                S    +  S +    S  ++  +++E                S S  S D      
Sbjct: 896  DSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSD 955

Query: 1585 SPVTSDWSDYRPDSDSEQPYKTSSDDPNDSGELTQEKEYNIGFVKRAIEKLYGKADIIKP 1644
            S  +SD S+    SDS     + S + +DS + +   + +              +D    
Sbjct: 956  SSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1015

Query: 1645 SFFPGSTRKSQVCPYNSVEFQCSRKASLYDSEGQSFGSSEQVSSSSSMLQEFQEERQDKC 1704
            S    S+  S     NS +   S  +S       S  SS+  +SS S       +  D  
Sbjct: 1016 SNSSDSSNSSD--SSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 1073

Query: 1705 DVSAVRDN 1712
            D S   D+
Sbjct: 1074 DSSDSSDS 1081


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
            sapiens]
          Length = 1972

 Score = 38.5 bits (88), Expect = 0.072
 Identities = 48/255 (18%), Positives = 105/255 (41%), Gaps = 22/255 (8%)

Query: 1330 DETYVPVNVCNTIDFLNSKENTYTDNLDSTEELERGDDIQKDLNILTDPEYKNGFNTLVS 1389
            +ET   +NV   +  L  + N+  D LD  EE+E   ++++ ++ L             S
Sbjct: 1326 EETRQKLNVSTKLRQLEEERNSLQDQLD--EEMEAKQNLERHISTL-------NIQLSDS 1376

Query: 1390 HQNVSNLSSCGLCLSEKEAELDKKHSSLDDFENCSLRKFQDENAYTSFDMEEPRTSEEPG 1449
             + + + +S    L E +    K      + EN + +  +   AY   +  + R  +E  
Sbjct: 1377 KKKLQDFASTVEALEEGKKRFQK------EIENLTQQYEEKAAAYDKLEKTKNRLQQELD 1430

Query: 1450 SITNSMTSSERNISELE----SFEELENHDTDIFNTVVNGGEQATEELIQEEVEASKTLE 1505
             +   + +  + +S LE     F++L   + +I +   +  ++A  E  ++E +A     
Sbjct: 1431 DLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLAR 1490

Query: 1506 LIDISSKNIMEEKRMNGIIYEIISKRLATPPSLDFCYDSKQNSEKETNEGETKMVKMMVK 1565
             ++ + +   E +R N ++   +   ++   S D    +    EK     ET+M +M  +
Sbjct: 1491 ALEEALEAKEELERTNKMLKAEMEDLVS---SKDDVGKNVHELEKSKRALETQMEEMKTQ 1547

Query: 1566 TMETGSYSESSPDLK 1580
              E     +++ D K
Sbjct: 1548 LEELEDELQATEDAK 1562


>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
            sapiens]
          Length = 1979

 Score = 38.5 bits (88), Expect = 0.072
 Identities = 48/255 (18%), Positives = 105/255 (41%), Gaps = 22/255 (8%)

Query: 1330 DETYVPVNVCNTIDFLNSKENTYTDNLDSTEELERGDDIQKDLNILTDPEYKNGFNTLVS 1389
            +ET   +NV   +  L  + N+  D LD  EE+E   ++++ ++ L             S
Sbjct: 1333 EETRQKLNVSTKLRQLEEERNSLQDQLD--EEMEAKQNLERHISTL-------NIQLSDS 1383

Query: 1390 HQNVSNLSSCGLCLSEKEAELDKKHSSLDDFENCSLRKFQDENAYTSFDMEEPRTSEEPG 1449
             + + + +S    L E +    K      + EN + +  +   AY   +  + R  +E  
Sbjct: 1384 KKKLQDFASTVEALEEGKKRFQK------EIENLTQQYEEKAAAYDKLEKTKNRLQQELD 1437

Query: 1450 SITNSMTSSERNISELE----SFEELENHDTDIFNTVVNGGEQATEELIQEEVEASKTLE 1505
             +   + +  + +S LE     F++L   + +I +   +  ++A  E  ++E +A     
Sbjct: 1438 DLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLAR 1497

Query: 1506 LIDISSKNIMEEKRMNGIIYEIISKRLATPPSLDFCYDSKQNSEKETNEGETKMVKMMVK 1565
             ++ + +   E +R N ++   +   ++   S D    +    EK     ET+M +M  +
Sbjct: 1498 ALEEALEAKEELERTNKMLKAEMEDLVS---SKDDVGKNVHELEKSKRALETQMEEMKTQ 1554

Query: 1566 TMETGSYSESSPDLK 1580
              E     +++ D K
Sbjct: 1555 LEELEDELQATEDAK 1569


>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
            sapiens]
          Length = 1945

 Score = 38.5 bits (88), Expect = 0.072
 Identities = 48/255 (18%), Positives = 105/255 (41%), Gaps = 22/255 (8%)

Query: 1330 DETYVPVNVCNTIDFLNSKENTYTDNLDSTEELERGDDIQKDLNILTDPEYKNGFNTLVS 1389
            +ET   +NV   +  L  + N+  D LD  EE+E   ++++ ++ L             S
Sbjct: 1333 EETRQKLNVSTKLRQLEEERNSLQDQLD--EEMEAKQNLERHISTL-------NIQLSDS 1383

Query: 1390 HQNVSNLSSCGLCLSEKEAELDKKHSSLDDFENCSLRKFQDENAYTSFDMEEPRTSEEPG 1449
             + + + +S    L E +    K      + EN + +  +   AY   +  + R  +E  
Sbjct: 1384 KKKLQDFASTVEALEEGKKRFQK------EIENLTQQYEEKAAAYDKLEKTKNRLQQELD 1437

Query: 1450 SITNSMTSSERNISELE----SFEELENHDTDIFNTVVNGGEQATEELIQEEVEASKTLE 1505
             +   + +  + +S LE     F++L   + +I +   +  ++A  E  ++E +A     
Sbjct: 1438 DLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLAR 1497

Query: 1506 LIDISSKNIMEEKRMNGIIYEIISKRLATPPSLDFCYDSKQNSEKETNEGETKMVKMMVK 1565
             ++ + +   E +R N ++   +   ++   S D    +    EK     ET+M +M  +
Sbjct: 1498 ALEEALEAKEELERTNKMLKAEMEDLVS---SKDDVGKNVHELEKSKRALETQMEEMKTQ 1554

Query: 1566 TMETGSYSESSPDLK 1580
              E     +++ D K
Sbjct: 1555 LEELEDELQATEDAK 1569


>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
            sapiens]
          Length = 1938

 Score = 38.5 bits (88), Expect = 0.072
 Identities = 48/255 (18%), Positives = 105/255 (41%), Gaps = 22/255 (8%)

Query: 1330 DETYVPVNVCNTIDFLNSKENTYTDNLDSTEELERGDDIQKDLNILTDPEYKNGFNTLVS 1389
            +ET   +NV   +  L  + N+  D LD  EE+E   ++++ ++ L             S
Sbjct: 1326 EETRQKLNVSTKLRQLEEERNSLQDQLD--EEMEAKQNLERHISTL-------NIQLSDS 1376

Query: 1390 HQNVSNLSSCGLCLSEKEAELDKKHSSLDDFENCSLRKFQDENAYTSFDMEEPRTSEEPG 1449
             + + + +S    L E +    K      + EN + +  +   AY   +  + R  +E  
Sbjct: 1377 KKKLQDFASTVEALEEGKKRFQK------EIENLTQQYEEKAAAYDKLEKTKNRLQQELD 1430

Query: 1450 SITNSMTSSERNISELE----SFEELENHDTDIFNTVVNGGEQATEELIQEEVEASKTLE 1505
             +   + +  + +S LE     F++L   + +I +   +  ++A  E  ++E +A     
Sbjct: 1431 DLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLAR 1490

Query: 1506 LIDISSKNIMEEKRMNGIIYEIISKRLATPPSLDFCYDSKQNSEKETNEGETKMVKMMVK 1565
             ++ + +   E +R N ++   +   ++   S D    +    EK     ET+M +M  +
Sbjct: 1491 ALEEALEAKEELERTNKMLKAEMEDLVS---SKDDVGKNVHELEKSKRALETQMEEMKTQ 1547

Query: 1566 TMETGSYSESSPDLK 1580
              E     +++ D K
Sbjct: 1548 LEELEDELQATEDAK 1562


>gi|4759082 serum deprivation response protein [Homo sapiens]
          Length = 425

 Score = 38.1 bits (87), Expect = 0.094
 Identities = 46/180 (25%), Positives = 77/180 (42%), Gaps = 19/180 (10%)

Query: 1460 RNISELESFEELENHDTDIF-NTVVNGGEQATEELIQEEVEASKTLELIDISS------- 1511
            RN  ++  F+E       +F    V+G  +  EEL  E     +TL  +D+SS       
Sbjct: 152  RNHFKVLIFQEENEIPASVFVKQPVSGAVEGKEELPDENKSLEETLHTVDLSSDDDLPHD 211

Query: 1512 ----KNIMEEKRMNGIIYEIISKRLATPPSLDFCYDSKQNSEKETNEGETKMVKM----M 1563
                ++  EEK       +I    L    SL   + S+QN EK+ N+  TK+V +     
Sbjct: 212  EEALEDSAEEKVEESRAEKIKRSSLKKVDSLKKAF-SRQNIEKKMNKLGTKIVSVERREK 270

Query: 1564 VKTMETGSYSESSPDLKKCIK-SPVTSDWSDYRPDSDSEQPYKTSSDDPNDSGELTQEKE 1622
            +K   T ++ + S       K SP+T      R + +S    +T S+D   S ++  ++E
Sbjct: 271  IKKSLTSNHQKISSGKSSPFKVSPLTFGRKKVR-EGESHAENETKSEDLPSSEQMPNDQE 329


>gi|151301098 zinc finger, DBF-type containing 2 [Homo sapiens]
          Length = 2354

 Score = 37.4 bits (85), Expect = 0.16
 Identities = 173/821 (21%), Positives = 297/821 (36%), Gaps = 133/821 (16%)

Query: 374  ESRSSGLKLAACSFSADVSPMERSSNQEGSLAEEINIQMTDQVAETCSSASWENATVDTD 433
            E RS     +  +F +D  P   S  ++  L  E   +  D   E+C S S E  T D+D
Sbjct: 739  EVRSYDCSSSELTFDSD--PPLLSVTEQSHLDAEGKERHIDLEDESCESDSSE-ITFDSD 795

Query: 434  I-IQGTQDQAKHRFYRPPTPGLRRVRQKKSVIGSVTLVSETEVQ----------EKMIGQ 482
            I +    DQ +   Y   T  L   +  +S +  +T  S+  +           +++I +
Sbjct: 796  IPLYSVIDQPEVAVYEEETVDLES-KSNESCVSEITFDSDIPLHSGNDHPEVAVKEVIQK 854

Query: 483  FSYSEERESGENKSEYHMFTHSCSKMSSVSNKPVLVQINNNDQMEESSLERKKENSLLKS 542
              Y       +  S   + + S + + SV+N P +     N Q EE      KEN  + S
Sbjct: 855  EEYIHLERKNDEPSGSEISSDSHAPLHSVTNSPEVAVKKLNPQKEEQVHLENKENEPIDS 914

Query: 543  ------SAISAGVIEITSQKMLEMSHNNGLPSTISNNSIVEEDVVDCVVLDNKTGIKN-- 594
                  + I   V   +   + E+S +      + N S+ E  +   V L   T      
Sbjct: 915  EVSLDYNIIFHSVTGRSEDPIKEISLHTKEHMYLENKSVFETSLDSDVPLQAATHKPEVI 974

Query: 595  FKTYGNTNDRFSPISADATHFSSNNSGTDKNISEAPASEASSTVTARIDR-----LINEF 649
             K      ++ +     +T FS + +  D  +     +E    V  +I+R     L N+ 
Sbjct: 975  VKETWLQREKHAEFQGRSTEFSGSKTSLDSGVPHYSVTEPQVAVN-KINRKKQYVLENKN 1033

Query: 650  AQCGLTKL------PKNEKKILSSVASKKKKKSRQQAINSRYQDGQL---------ATKG 694
             +C  +++      P         +A  K+K    +  NS+  D ++         A K 
Sbjct: 1034 DKCSGSEIILDSNVPPQSMTDQPQLAFLKEKHVNLKDKNSKSGDSKITFDSEQLQEAVKK 1093

Query: 695  ILN-KNERINTKGRITK----------EMIVQD-SDSP---LKGGILCEEDLQKSDTVIE 739
            I   K E I  K +I +          ++ VQ  +D P   +K   L  E+    + V  
Sbjct: 1094 IDQWKEEVIGLKNKINEPSTYKLIHHPDVSVQSVADQPKVAIKHVNLGNENHMYLE-VKN 1152

Query: 740  SNTFCSKSNLNS-------------TISKNFH---RNKLNTTQNSKVQ-------GLLTK 776
            S   CS+ NL+S             TI +  H     K N    S+V          +  
Sbjct: 1153 SQYSCSEMNLDSGFLGQSIVNRPQITILEQEHIELEGKHNQCCGSEVSFDSDDPLQSVAD 1212

Query: 777  RKSRSLNKISLGAPKKREIGQRDKVFPHNESKYCKSTFENKSLFHVFNILEQKPKDFYAP 836
            R   ++ +ISL   K  E+   D+    NE+K  +  +++  L  V    E+  K+    
Sbjct: 1213 RLRETVKEISLW--KDEEVDTEDR---RNEAKGFEIMYDSDVLQPVAGQPEEVVKEVSLW 1267

Query: 837  QSQAEVASGYLRGMAKKSLVSKVT-DSHITLKSQKKRKGDKVKASAILSKQHATTRANSL 895
            +   +     L     K   S++  DSH  L+S   +     K   +L ++H        
Sbjct: 1268 KEHVD-----LENKIVKPTDSRINFDSHEPLQSVTNKIPGANKEINLLREEHVCLDDKGY 1322

Query: 896  ASLKKPDFPEAIAHHSIQNYIQSWLQNINPYPTLKPIKSAPVCRNE-TSVVNCSNNSFSG 954
                 P   E I           ++ NI   P    IK   +   E  S+ + S+NS+S 
Sbjct: 1323 V----PSDSEII-----------YVSNI---PLQSVIKQPHILEEEHASLEDKSSNSYSP 1364

Query: 955  NDPHTNSGKISNFVMESNKHITKIAGLTGDNLCKEGDKSFIANDTGEEDLHETQVGSLND 1014
             +   ++        E  K + +I     D++  E DKS+   D          V  + D
Sbjct: 1365 EESSDSNDSFQAAADELQKPVKEINLWKEDHIYLE-DKSYKLGDFDVSYASHIPVQFVTD 1423

Query: 1015 AYLVPLHE--------------HCTLSQSAINDHNTKSHIAAEKSGPEKKLVYQEINLAR 1060
               VP+ E              +C +  S I  H+   H+ +E   P+  + Y+E +L +
Sbjct: 1424 QSSVPVKEINLQKKDHNDLENKNCEVCGSEIKCHSC-VHLQSEVDQPQ--VSYKEADLQK 1480

Query: 1061 KRQSV--EAAIQVDPIEEETPKDLLPVLMLHQLQASVPGIH 1099
            +   V  E   Q    E     D+   ++++Q   SV   H
Sbjct: 1481 EEHVVMEEKTDQPSDSEMMYDSDVPFQIVVNQFPGSVKETH 1521


>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 37.0 bits (84), Expect = 0.21
 Identities = 76/336 (22%), Positives = 122/336 (36%), Gaps = 66/336 (19%)

Query: 1418 DDFENCSLRKFQDENAYTSFDMEEPRTSEEPGSITNSMTSSER----NISELESFEELEN 1473
            DD    S +K + E   T  D++E    +E     N   S E+      +EL+S EE  +
Sbjct: 1320 DDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPS 1379

Query: 1474 HDTDIFNTVVNGGE-------QATEELI----QEEVEASK-TLELIDISSKNIMEEKRMN 1521
            HDT + +  + G E          EELI    +EE+  S+  LE +        EE   +
Sbjct: 1380 HDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEH 1439

Query: 1522 GIIYEIISKRLATPPSL---------------DFCYDSKQNS-----EKETNEGETKMVK 1561
               Y+   + LA   +L               + C+ S+ NS     +   ++    +  
Sbjct: 1440 EGAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVRSVSS 1499

Query: 1562 MMVKTMETGSYSESSPD----LKKCIKSPVTSDWSDYRPDSDSEQPYKTSSDDPNDSGEL 1617
              V  +E+G Y++ SP+        +++  TS   D    SD  Q    S      S E 
Sbjct: 1500 PNVPALESG-YTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIES 1558

Query: 1618 TQEKEYNIGFVKRAIEKLYGKADIIKPSFFPGSTRKSQVCPYNSVEFQC-----SRKASL 1672
            T E   N                   PS +  ST    +C  +S +  C     S  +SL
Sbjct: 1559 TTENYEN-------------------PSSY-DSTMGGSICGNSSSQSSCSYGGLSSSSSL 1598

Query: 1673 YDSEGQSFGSSEQVSSSSSMLQEFQEERQDKCDVSA 1708
              S          + SS SM+Q+   +    C + +
Sbjct: 1599 TQSSCVVTQQMASMGSSCSMMQQSSVQPAANCSIKS 1634


>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 37.0 bits (84), Expect = 0.21
 Identities = 76/336 (22%), Positives = 122/336 (36%), Gaps = 66/336 (19%)

Query: 1418 DDFENCSLRKFQDENAYTSFDMEEPRTSEEPGSITNSMTSSER----NISELESFEELEN 1473
            DD    S +K + E   T  D++E    +E     N   S E+      +EL+S EE  +
Sbjct: 1320 DDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPS 1379

Query: 1474 HDTDIFNTVVNGGE-------QATEELI----QEEVEASK-TLELIDISSKNIMEEKRMN 1521
            HDT + +  + G E          EELI    +EE+  S+  LE +        EE   +
Sbjct: 1380 HDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEH 1439

Query: 1522 GIIYEIISKRLATPPSL---------------DFCYDSKQNS-----EKETNEGETKMVK 1561
               Y+   + LA   +L               + C+ S+ NS     +   ++    +  
Sbjct: 1440 EGAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVRSVSS 1499

Query: 1562 MMVKTMETGSYSESSPD----LKKCIKSPVTSDWSDYRPDSDSEQPYKTSSDDPNDSGEL 1617
              V  +E+G Y++ SP+        +++  TS   D    SD  Q    S      S E 
Sbjct: 1500 PNVPALESG-YTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIES 1558

Query: 1618 TQEKEYNIGFVKRAIEKLYGKADIIKPSFFPGSTRKSQVCPYNSVEFQC-----SRKASL 1672
            T E   N                   PS +  ST    +C  +S +  C     S  +SL
Sbjct: 1559 TTENYEN-------------------PSSY-DSTMGGSICGNSSSQSSCSYGGLSSSSSL 1598

Query: 1673 YDSEGQSFGSSEQVSSSSSMLQEFQEERQDKCDVSA 1708
              S          + SS SM+Q+   +    C + +
Sbjct: 1599 TQSSCVVTQQMASMGSSCSMMQQSSVQPAANCSIKS 1634


>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 37.0 bits (84), Expect = 0.21
 Identities = 76/336 (22%), Positives = 122/336 (36%), Gaps = 66/336 (19%)

Query: 1418 DDFENCSLRKFQDENAYTSFDMEEPRTSEEPGSITNSMTSSER----NISELESFEELEN 1473
            DD    S +K + E   T  D++E    +E     N   S E+      +EL+S EE  +
Sbjct: 1320 DDGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPS 1379

Query: 1474 HDTDIFNTVVNGGE-------QATEELI----QEEVEASK-TLELIDISSKNIMEEKRMN 1521
            HDT + +  + G E          EELI    +EE+  S+  LE +        EE   +
Sbjct: 1380 HDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEH 1439

Query: 1522 GIIYEIISKRLATPPSL---------------DFCYDSKQNS-----EKETNEGETKMVK 1561
               Y+   + LA   +L               + C+ S+ NS     +   ++    +  
Sbjct: 1440 EGAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVRSVSS 1499

Query: 1562 MMVKTMETGSYSESSPD----LKKCIKSPVTSDWSDYRPDSDSEQPYKTSSDDPNDSGEL 1617
              V  +E+G Y++ SP+        +++  TS   D    SD  Q    S      S E 
Sbjct: 1500 PNVPALESG-YTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIES 1558

Query: 1618 TQEKEYNIGFVKRAIEKLYGKADIIKPSFFPGSTRKSQVCPYNSVEFQC-----SRKASL 1672
            T E   N                   PS +  ST    +C  +S +  C     S  +SL
Sbjct: 1559 TTENYEN-------------------PSSY-DSTMGGSICGNSSSQSSCSYGGLSSSSSL 1598

Query: 1673 YDSEGQSFGSSEQVSSSSSMLQEFQEERQDKCDVSA 1708
              S          + SS SM+Q+   +    C + +
Sbjct: 1599 TQSSCVVTQQMASMGSSCSMMQQSSVQPAANCSIKS 1634


>gi|47717112 zinc finger, FYVE domain containing 9 isoform 1 [Homo
            sapiens]
          Length = 1366

 Score = 36.6 bits (83), Expect = 0.27
 Identities = 43/173 (24%), Positives = 72/173 (41%), Gaps = 26/173 (15%)

Query: 1330 DETYVPVNVCNTIDFLNSKENTYTDNLDSTE----ELERGDDIQKDLNILTDPEYKNGFN 1385
            +E Y       T +FLN  E+ ++++ D T     +L   +D Q +       E K  F 
Sbjct: 372  NEGYEHEETLGTTEFLNMTEH-FSESQDMTNWKLTKLNEMNDSQVN-------EEKEKF- 422

Query: 1386 TLVSHQNVSNLSSCGLCLSEKEAELDKKHSSLDDFENCSLRKFQD-------ENAYTSFD 1438
              +S    +N  S G C+   +A LD K + + + E C      D        N   S+ 
Sbjct: 423  LQISQPEDTNGDSGGQCVGLADAGLDLKGTCISESEECDFSTVIDTPAANYLSNGCDSYG 482

Query: 1439 MEEPRTSEEPGSITNSMTSSERNISELESFEELENHDTDIFNTVVNGGEQATE 1491
            M++P  S  P     ++ S E +++E +  EE ++      N     G +ATE
Sbjct: 483  MQDPGVSFVP----KTLPSKEDSVTEEKEIEESKSECYS--NIYEQRGNEATE 529


>gi|47717106 zinc finger, FYVE domain containing 9 isoform 3 [Homo
            sapiens]
          Length = 1425

 Score = 36.6 bits (83), Expect = 0.27
 Identities = 43/173 (24%), Positives = 72/173 (41%), Gaps = 26/173 (15%)

Query: 1330 DETYVPVNVCNTIDFLNSKENTYTDNLDSTE----ELERGDDIQKDLNILTDPEYKNGFN 1385
            +E Y       T +FLN  E+ ++++ D T     +L   +D Q +       E K  F 
Sbjct: 372  NEGYEHEETLGTTEFLNMTEH-FSESQDMTNWKLTKLNEMNDSQVN-------EEKEKF- 422

Query: 1386 TLVSHQNVSNLSSCGLCLSEKEAELDKKHSSLDDFENCSLRKFQD-------ENAYTSFD 1438
              +S    +N  S G C+   +A LD K + + + E C      D        N   S+ 
Sbjct: 423  LQISQPEDTNGDSGGQCVGLADAGLDLKGTCISESEECDFSTVIDTPAANYLSNGCDSYG 482

Query: 1439 MEEPRTSEEPGSITNSMTSSERNISELESFEELENHDTDIFNTVVNGGEQATE 1491
            M++P  S  P     ++ S E +++E +  EE ++      N     G +ATE
Sbjct: 483  MQDPGVSFVP----KTLPSKEDSVTEEKEIEESKSECYS--NIYEQRGNEATE 529


>gi|6552337 zinc finger, FYVE domain containing 9 isoform 2 [Homo
            sapiens]
          Length = 762

 Score = 36.6 bits (83), Expect = 0.27
 Identities = 43/173 (24%), Positives = 72/173 (41%), Gaps = 26/173 (15%)

Query: 1330 DETYVPVNVCNTIDFLNSKENTYTDNLDSTE----ELERGDDIQKDLNILTDPEYKNGFN 1385
            +E Y       T +FLN  E+ ++++ D T     +L   +D Q +       E K  F 
Sbjct: 372  NEGYEHEETLGTTEFLNMTEH-FSESQDMTNWKLTKLNEMNDSQVN-------EEKEKF- 422

Query: 1386 TLVSHQNVSNLSSCGLCLSEKEAELDKKHSSLDDFENCSLRKFQD-------ENAYTSFD 1438
              +S    +N  S G C+   +A LD K + + + E C      D        N   S+ 
Sbjct: 423  LQISQPEDTNGDSGGQCVGLADAGLDLKGTCISESEECDFSTVIDTPAANYLSNGCDSYG 482

Query: 1439 MEEPRTSEEPGSITNSMTSSERNISELESFEELENHDTDIFNTVVNGGEQATE 1491
            M++P  S  P     ++ S E +++E +  EE ++      N     G +ATE
Sbjct: 483  MQDPGVSFVP----KTLPSKEDSVTEEKEIEESKSECYS--NIYEQRGNEATE 529


>gi|239747116 PREDICTED: hypothetical protein XP_002343915 isoform 2
           [Homo sapiens]
          Length = 551

 Score = 35.8 bits (81), Expect = 0.47
 Identities = 47/220 (21%), Positives = 80/220 (36%), Gaps = 20/220 (9%)

Query: 359 SNNDEKSEMSFPGRTESRSSGLKLAACSFSADVSPMERSSNQEGSLAEEINIQMTDQVAE 418
           S+  EK  +       +    LKL +   S  +   E S  ++ S   EIN     +V E
Sbjct: 325 SDYKEKQMLKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPEINKDCDREVEE 384

Query: 419 TCSSASWENATVDTDIIQGTQDQAKHRFYRPPTPGLRRVRQKKSVIGSVTLVSETEVQEK 478
                      +  ++  G           P     RR R+ ++     T   E    E+
Sbjct: 385 EIKKHGSNPVGLPENLTNGASAGNGDDGLIPQ----RRSRKPENQQFPDTENEEYHSDEQ 440

Query: 479 MIGQFSYSEERESGENKSEYHMFTHSCSKMSSVSNKPVLVQINNNDQMEESSLERKKENS 538
              +   SEE+ +G ++ E             ++NK   +++       E SL  KKE  
Sbjct: 441 NDTRKQLSEEQNTGISQDEI------------LTNKQKQIEVAEQKMNSELSLSHKKEED 488

Query: 539 LLKSSAISAGVIEITSQKMLEMSHNNGLPSTISNNSIVEE 578
           LL+ +++    I +   ++ E  H N L      N I+EE
Sbjct: 489 LLRENSVLQEEIAVLRLELDETKHQNQL----RENKILEE 524


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.128    0.363 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 82,822,396
Number of Sequences: 37866
Number of extensions: 3867487
Number of successful extensions: 10358
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 75
Number of HSP's that attempted gapping in prelim test: 10091
Number of HSP's gapped (non-prelim): 281
length of query: 2156
length of database: 18,247,518
effective HSP length: 118
effective length of query: 2038
effective length of database: 13,779,330
effective search space: 28082274540
effective search space used: 28082274540
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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