Search of human proteins with 49087132

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|49087132 sal-like 2 [Homo sapiens]
         (1007 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|49087132 sal-like 2 [Homo sapiens]                                2044   0.0  
gi|154146199 sal-like 3 [Homo sapiens]                                470   e-132
gi|118442837 sal-like 1 isoform a [Homo sapiens]                      458   e-128
gi|189217876 sal-like 1 isoform b [Homo sapiens]                      424   e-118
gi|10047144 sal-like 4 [Homo sapiens]                                 350   5e-96
gi|138175817 zinc finger protein 236 [Homo sapiens]                   109   1e-23
gi|69885084 p120E4F [Homo sapiens]                                     87   6e-17
gi|74027276 zinc finger protein 226 isoform a [Homo sapiens]           84   9e-16
gi|74027274 zinc finger protein 226 isoform a [Homo sapiens]           84   9e-16
gi|239757409 PREDICTED: similar to zinc finger protein 208 [Homo...    81   4e-15
gi|239746371 PREDICTED: similar to zinc finger protein 208 [Homo...    81   4e-15
gi|153791350 replication initiator 1 isoform 1 [Homo sapiens]          79   2e-14
gi|153792539 replication initiator 1 isoform 1 [Homo sapiens]          79   2e-14
gi|153792647 replication initiator 1 isoform 3 [Homo sapiens]          79   2e-14
gi|153791994 replication initiator 1 isoform 1 [Homo sapiens]          79   2e-14
gi|170932550 FLT3-interacting zinc finger 1 [Homo sapiens]             79   2e-14
gi|189181750 human immunodeficiency virus type I enhancer bindin...    79   3e-14
gi|116089331 human immunodeficiency virus type I enhancer bindin...    79   3e-14
gi|51173737 ras responsive element binding protein 1 isoform 1 [...    77   1e-13
gi|110681708 zinc finger protein 579 [Homo sapiens]                    75   2e-13
gi|172072684 PR domain containing 1, with ZNF domain isoform 1 [...    75   3e-13
gi|33946274 PR domain containing 1, with ZNF domain isoform 2 [H...    75   3e-13
gi|156416026 zinc finger protein 219 [Homo sapiens]                    75   3e-13
gi|156415998 zinc finger protein 219 [Homo sapiens]                    75   3e-13
gi|156415996 zinc finger protein 219 [Homo sapiens]                    75   3e-13
gi|32469511 B-cell CLL/lymphoma 6, member B (zinc finger protein...    75   4e-13
gi|194018515 zinc finger protein 443 [Homo sapiens]                    73   2e-12
gi|33438586 zinc finger protein 77 [Homo sapiens]                      72   3e-12
gi|37693995 Kruppel-like factor 13 [Homo sapiens]                      72   3e-12
gi|148276990 zinc finger and BTB domain containing 38 [Homo sapi...    71   4e-12

>gi|49087132 sal-like 2 [Homo sapiens]
          Length = 1007

 Score = 2044 bits (5296), Expect = 0.0
 Identities = 1007/1007 (100%), Positives = 1007/1007 (100%)

Query: 1    MSRRKQRKPQQLISDCEGPSASENGDASEEDHPQVCAKCCAQFTDPTEFLAHQNACSTDP 60
            MSRRKQRKPQQLISDCEGPSASENGDASEEDHPQVCAKCCAQFTDPTEFLAHQNACSTDP
Sbjct: 1    MSRRKQRKPQQLISDCEGPSASENGDASEEDHPQVCAKCCAQFTDPTEFLAHQNACSTDP 60

Query: 61   PVMVIIGGQENPNNSSASSEPRPEGHNNPQVMDTEHSNPPDSGSSVPTDPTWGPERRGEE 120
            PVMVIIGGQENPNNSSASSEPRPEGHNNPQVMDTEHSNPPDSGSSVPTDPTWGPERRGEE
Sbjct: 61   PVMVIIGGQENPNNSSASSEPRPEGHNNPQVMDTEHSNPPDSGSSVPTDPTWGPERRGEE 120

Query: 121  SPGHFLVAATGTAAGGGGGLILASPKLGATPLPPESTPAPPPPPPPPPPPGVGSGHLNIP 180
            SPGHFLVAATGTAAGGGGGLILASPKLGATPLPPESTPAPPPPPPPPPPPGVGSGHLNIP
Sbjct: 121  SPGHFLVAATGTAAGGGGGLILASPKLGATPLPPESTPAPPPPPPPPPPPGVGSGHLNIP 180

Query: 181  LILEELRVLQQRQIHQMQMTEQICRQVLLLGSLGQTVGAPASPSELPGTGTASSTKPLLP 240
            LILEELRVLQQRQIHQMQMTEQICRQVLLLGSLGQTVGAPASPSELPGTGTASSTKPLLP
Sbjct: 181  LILEELRVLQQRQIHQMQMTEQICRQVLLLGSLGQTVGAPASPSELPGTGTASSTKPLLP 240

Query: 241  LFSPIKPVQTSKTLASSSSSSSSSSGAETPKQAFFHLYHPLGSQHPFSAGGVGRSHKPTP 300
            LFSPIKPVQTSKTLASSSSSSSSSSGAETPKQAFFHLYHPLGSQHPFSAGGVGRSHKPTP
Sbjct: 241  LFSPIKPVQTSKTLASSSSSSSSSSGAETPKQAFFHLYHPLGSQHPFSAGGVGRSHKPTP 300

Query: 301  APSPALPGSTDQLIASPHLAFPSTTGLLAAQCLGAARGLEATASPGLLKPKNGSGELSYG 360
            APSPALPGSTDQLIASPHLAFPSTTGLLAAQCLGAARGLEATASPGLLKPKNGSGELSYG
Sbjct: 301  APSPALPGSTDQLIASPHLAFPSTTGLLAAQCLGAARGLEATASPGLLKPKNGSGELSYG 360

Query: 361  EVMGPLEKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHF 420
            EVMGPLEKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHF
Sbjct: 361  EVMGPLEKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHF 420

Query: 421  HRHREKYPHVQMNPHPVPEHLDYVITSSGLPYGMSVPPEKAEEEAATPGGGVERKPLVAS 480
            HRHREKYPHVQMNPHPVPEHLDYVITSSGLPYGMSVPPEKAEEEAATPGGGVERKPLVAS
Sbjct: 421  HRHREKYPHVQMNPHPVPEHLDYVITSSGLPYGMSVPPEKAEEEAATPGGGVERKPLVAS 480

Query: 481  TTALSATESLTLLSTSAGTATAPGLPAFNKFVLMKAVEPKNKADENTPPGSEGSAISGVA 540
            TTALSATESLTLLSTSAGTATAPGLPAFNKFVLMKAVEPKNKADENTPPGSEGSAISGVA
Sbjct: 481  TTALSATESLTLLSTSAGTATAPGLPAFNKFVLMKAVEPKNKADENTPPGSEGSAISGVA 540

Query: 541  ESSTATRMQLSKLVTSLPSWALLTNHFKSTGSFPFPYVLEPLGASPSETSKLQQLVEKID 600
            ESSTATRMQLSKLVTSLPSWALLTNHFKSTGSFPFPYVLEPLGASPSETSKLQQLVEKID
Sbjct: 541  ESSTATRMQLSKLVTSLPSWALLTNHFKSTGSFPFPYVLEPLGASPSETSKLQQLVEKID 600

Query: 601  RQGAVAVTSAASGAPTTSAPAPSSSASSGPNQCVICLRVLSCPRALRLHYGQHGGERPFK 660
            RQGAVAVTSAASGAPTTSAPAPSSSASSGPNQCVICLRVLSCPRALRLHYGQHGGERPFK
Sbjct: 601  RQGAVAVTSAASGAPTTSAPAPSSSASSGPNQCVICLRVLSCPRALRLHYGQHGGERPFK 660

Query: 661  CKVCGRAFSTRGNLRAHFVGHKASPAARAQNSCPICQKKFTNAVTLQQHVRMHLGGQIPN 720
            CKVCGRAFSTRGNLRAHFVGHKASPAARAQNSCPICQKKFTNAVTLQQHVRMHLGGQIPN
Sbjct: 661  CKVCGRAFSTRGNLRAHFVGHKASPAARAQNSCPICQKKFTNAVTLQQHVRMHLGGQIPN 720

Query: 721  GGTALPEGGGAAQENGSEQSTVSGAGSFPQQQSQQPSPEEELSEEEEEEDEEEEEDVTDE 780
            GGTALPEGGGAAQENGSEQSTVSGAGSFPQQQSQQPSPEEELSEEEEEEDEEEEEDVTDE
Sbjct: 721  GGTALPEGGGAAQENGSEQSTVSGAGSFPQQQSQQPSPEEELSEEEEEEDEEEEEDVTDE 780

Query: 781  DSLAGRGSESGGEKAISVRGDSEEASGAEEEVGTVAAAATAGKEMDSNEKTTQQSSLPPP 840
            DSLAGRGSESGGEKAISVRGDSEEASGAEEEVGTVAAAATAGKEMDSNEKTTQQSSLPPP
Sbjct: 781  DSLAGRGSESGGEKAISVRGDSEEASGAEEEVGTVAAAATAGKEMDSNEKTTQQSSLPPP 840

Query: 841  PPPDSLDQPQPMEQGSSGVLGGKEEGGKPERSSSPASALTPEGEATSVTLVEELSLQEAM 900
            PPPDSLDQPQPMEQGSSGVLGGKEEGGKPERSSSPASALTPEGEATSVTLVEELSLQEAM
Sbjct: 841  PPPDSLDQPQPMEQGSSGVLGGKEEGGKPERSSSPASALTPEGEATSVTLVEELSLQEAM 900

Query: 901  RKEPGESSSRKACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHML 960
            RKEPGESSSRKACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHML
Sbjct: 901  RKEPGESSSRKACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHML 960

Query: 961  LAHHQVQPFAPHGPQNIAALSLVPGCSPSITSTGLSPFPRKDDPTIP 1007
            LAHHQVQPFAPHGPQNIAALSLVPGCSPSITSTGLSPFPRKDDPTIP
Sbjct: 961  LAHHQVQPFAPHGPQNIAALSLVPGCSPSITSTGLSPFPRKDDPTIP 1007


>gi|154146199 sal-like 3 [Homo sapiens]
          Length = 1300

 Score =  470 bits (1210), Expect = e-132
 Identities = 378/1165 (32%), Positives = 507/1165 (43%), Gaps = 280/1165 (24%)

Query: 1    MSRRKQRKPQQLISDCE------GPSASENGDASEE-----------DHPQVCAKCCAQF 43
            MSRRKQ KPQ L SD E       P  +  G+ +E+           +   VC KCCA+F
Sbjct: 1    MSRRKQAKPQHLKSDEELLPPDGAPEHAAPGEGAEDADSGPESRSGGEETSVCEKCCAEF 60

Query: 44   TDPTEFLAHQNACSTDPPVMVIIGGQENPNNSSASSEPRPEGHNNPQVMDTEHSNPPDSG 103
                +FL HQ +C+  PPV+++            +  P PE    P    +  S+P +  
Sbjct: 61   FKWADFLEHQRSCTKLPPVLIV---------HEDAPAPPPEDFPEP----SPASSPSERA 107

Query: 104  SSVPTDPTWGPERRGEESPGHFLVAATGTAAGGGGGLILASPKLGATPLPPESTPAPPPP 163
             S   +        GE  P                 +   +  + A P      P PPP 
Sbjct: 108  ESEAAEEAGAEGAEGEARP-----------------VEKEAEPMDAEPAGDTRAPRPPPA 150

Query: 164  PPPPPPPGVGSGHLNI------------------------------------PLILEELR 187
             P PP P  G+   N+                                    PLILE+L 
Sbjct: 151  APAPPTPAYGAPSTNVTLEALLSTKVAVAQFSQGARAAGGSGAGGGVAAAAVPLILEQLM 210

Query: 188  VLQQRQIHQMQMTEQICRQVLLLG--------SLGQTVGAPA-SPSELPGTG----TASS 234
             LQQ+QIHQ+Q+ EQI  QV L+         S      AP  +PS+LPG      +A +
Sbjct: 211  ALQQQQIHQLQLIEQIRSQVALMQRPPPRPSLSPAAAPSAPGPAPSQLPGLAALPLSAGA 270

Query: 235  TKPLLPLFSPIKPVQTSKTLASSSSSSSSSSGAETPKQAFFHLYHPLGSQHPFSAGGVGR 294
                +    P  P         +   S   SGA TP         P     P +      
Sbjct: 271  PAAAIAGSGPAAPA----AFEGAQPLSRPESGASTPGG-------PAEPSAPAAPSAAPA 319

Query: 295  SHKPTPAPSPALPGSTDQLIASPHLAFPSTTGLLAAQCLGAARGLEA-----TASPGLLK 349
               P PAP+P    S+    AS      +   L     LGAA GL +     T++ G++ 
Sbjct: 320  PAAPAPAPAPQSAASSQPQSAS------TPPALAPGSLLGAAPGLPSPLLPQTSASGVIF 373

Query: 350  P-----------------------KNGSGELSYGEVMGPLEKPGGRHKCRFCAKVFGSDS 386
            P                       K     +S  E     E P  +HKCRFCAKVFGSDS
Sbjct: 374  PNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDS 433

Query: 387  ALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPHVQMNPHPVPEHLDYVIT 446
            ALQIHLRSHTGERP+KCN+CGNRF+T+GNLKVHF RH+EKYPH+QMNP+PVPE+LD V T
Sbjct: 434  ALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEYLDNVPT 493

Query: 447  SSGLPYGMSVPPEK---------------------------------AEEEAATPGGGVE 473
             SG+PYGMS+PPEK                                 A+  +ATP     
Sbjct: 494  CSGIPYGMSLPPEKPVTTWLDSKPVLPTVPTSVGLQLPPTVPGAHGYADSPSATPASRSP 553

Query: 474  RKPLVASTTALSATESLTLLSTS-AGTATAP----GLPAFNKFVLMKAVEPKNKADENTP 528
            ++P  AS+   S +  L  + +  + TA +P    G P   K       EP +    N  
Sbjct: 554  QRPSPASSECASLSPGLNHVESGVSATAESPQSLLGGPPLTK------AEPVSLPCTNA- 606

Query: 529  PGSEGSAISGVAESSTATRMQLSKLVTSLPSWALLTNHFKSTGSFPFPYVLEPLGASPSE 588
                G A  G   S+  T +  +      P    ++  FK+   FPF  +L+ +    SE
Sbjct: 607  --RAGDAPVGAQASAAPTSVDGAPTSLGSPGLPAVSEQFKA--QFPFGGLLDSM--QTSE 660

Query: 589  TSKLQQLVEKIDRQGAVAVTSAASGAPTTSAPAPSSSASSGPNQCVICLRVLSCPRALRL 648
            TSKLQQLVE ID++                         + PNQCVIC RVLSC  AL++
Sbjct: 661  TSKLQQLVENIDKK------------------------MTDPNQCVICHRVLSCQSALKM 696

Query: 649  HYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARAQNSCPICQKKFTNAVTLQQ 708
            HY  H GERPFKCK+CGRAF+T+GNL+ HF  H+A P  R Q+SCPICQKKFTNAV LQQ
Sbjct: 697  HYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQ 756

Query: 709  HVRMHLGGQIPNGGTALPEGGGAAQENGSEQSTVSGAGSFPQQQSQQPSPEEELSEEEEE 768
            H+RMH+GGQIPN  T LPEG          Q  +    ++  + ++  S  ++  +E   
Sbjct: 757  HIRMHMGGQIPN--TPLPEG---------FQDAMDSELAYDDKNAETLSSYDDDMDENSM 805

Query: 769  EDEEEEEDVTDED-----SLAGRGSESGGEKAISVRG--------DS------------- 802
            ED+ E +D   +      S AG    S      S+          DS             
Sbjct: 806  EDDAELKDAATDPAKPLLSYAGSCPPSPPSVISSIAALENQMKMIDSVMSCQQLTGLKSV 865

Query: 803  EEASGAEEEVGTVAAAATAGKEMDS------NEKTTQQSSLPPPPPPDSLDQPQPMEQGS 856
            E  SG  + +   +++A    E  S      +E ++ Q+  P P   +S     P     
Sbjct: 866  ENGSGESDRLSNDSSSAVGDLESRSAGSPALSESSSSQALSPAPSNGESFRSKSP----- 920

Query: 857  SGVLGGKEEGG----KPERSSSPASALTPEGEATSVTLVEELSLQEA-MRKEPGESSSRK 911
               LG  EE      K ER  SPA+A    G      + EE       + +E G+  S  
Sbjct: 921  --GLGAPEEPQEIPLKTERPDSPAAAPGSGGAPGRAGIKEEAPFSLLFLSRERGKCPS-T 977

Query: 912  ACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHML---LAHHQVQP 968
             C VCG+ F  ++ALE H ++H KE P F C  CR+G      LK+H+L   L     Q 
Sbjct: 978  VCGVCGKPFACKSALEIHYRSHTKERP-FVCALCRRGCSTMGNLKQHLLTHRLKELPSQL 1036

Query: 969  FAPH---GPQNIAALSLVPGCSPSI 990
            F P+   GP   +  SL+   +P++
Sbjct: 1037 FDPNFALGPSQ-STPSLISSAAPTM 1060



 Score = 77.0 bits (188), Expect = 8e-14
 Identities = 32/59 (54%), Positives = 40/59 (67%)

Query: 365  PLEKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRH 423
            P  +   +H C+ C K F S SALQIH R+HTGE+P+ C +CG  FTT+GNLKVH   H
Sbjct: 1105 PPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 45/151 (29%), Positives = 65/151 (43%), Gaps = 22/151 (14%)

Query: 562  LLTNHFKSTGSFPFP--YVLEPLGASPSETSKLQQLVEKIDRQGAVAVTSAASGAP---- 615
            LLT+  K   S  F   + L P  ++PS  S     + K++  G     +   G P    
Sbjct: 1024 LLTHRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAG 1083

Query: 616  --------TTSAP------APSSSASSGPNQCVICLRVLSCPRALRLHYGQHGGERPFKC 661
                    T   P      AP    +   + C  C +  S   AL++H   H GE+PF C
Sbjct: 1084 VQVPAGPQTVMGPGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGC 1143

Query: 662  KVCGRAFSTRGNLRAHFVGH--KASPAARAQ 690
             +CGRAF+T+GNL+ H   H    +PA R +
Sbjct: 1144 TICGRAFTTKGNLKVHMGTHMWNNAPARRGR 1174



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 28/85 (32%), Positives = 39/85 (45%), Gaps = 5/85 (5%)

Query: 875  PASALTPEGEATSVTLVEELSLQEAMRKEPGESSSRKACEVCGQAFPSQAALEEHQKTHP 934
            PA    P G  T    V    L   +   P  +  +  C+ CG+ F S +AL+ H++TH 
Sbjct: 1081 PAGVQVPAGPQT----VMGPGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHT 1136

Query: 935  KEGPLFTCVFCRQGFLERATLKKHM 959
             E P F C  C + F  +  LK HM
Sbjct: 1137 GEKP-FGCTICGRAFTTKGNLKVHM 1160



 Score = 34.3 bits (77), Expect = 0.61
 Identities = 67/280 (23%), Positives = 112/280 (40%), Gaps = 38/280 (13%)

Query: 459  EKAEEEAATPGGGVERKPLVASTTALSATESLTLLSTSAGT-----ATAPGL--PAFNKF 511
            ++   ++++  G +E +   A + ALS + S   LS +        + +PGL  P   + 
Sbjct: 873  DRLSNDSSSAVGDLESRS--AGSPALSESSSSQALSPAPSNGESFRSKSPGLGAPEEPQE 930

Query: 512  VLMKAVEPKNKADENTPPGSEGS-AISGVAESSTATRMQLSKLVTSLPSW---------- 560
            + +K   P + A     PGS G+   +G+ E +  + + LS+     PS           
Sbjct: 931  IPLKTERPDSPA---AAPGSGGAPGRAGIKEEAPFSLLFLSRERGKCPSTVCGVCGKPFA 987

Query: 561  --ALLTNHFKS-TGSFPFPYVLEPLGASPSETSKLQQLVEKIDRQGAVAVTSAASGAPTT 617
              + L  H++S T   PF   L   G S     K   L  ++    +       +  P+ 
Sbjct: 988  CKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFDPNFALGPSQ 1047

Query: 618  SAPAPSSSASSGPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAH 677
            S P+  SSA+      +I + V    +A+ L     G   P   +V     +  G   A 
Sbjct: 1048 STPSLISSAAP----TMIKMEVNGHGKAMALG---EGPPLPAGVQVPAGPQTVMGPGLAP 1100

Query: 678  FVGHKASPAARA--QNSCPICQKKFTNAVTLQQHVRMHLG 715
             +   A P  R   Q++C  C K F++A  LQ H R H G
Sbjct: 1101 ML---APPPRRTPKQHNCQSCGKTFSSASALQIHERTHTG 1137


>gi|118442837 sal-like 1 isoform a [Homo sapiens]
          Length = 1324

 Score =  458 bits (1179), Expect = e-128
 Identities = 369/1165 (31%), Positives = 526/1165 (45%), Gaps = 220/1165 (18%)

Query: 1    MSRRKQRKPQQLISDCEGPSASENGDASEEDHPQ---------VCAKCCAQFTDPTEFLA 51
            MSRRKQ KPQ   SD E  S       +E+  P          VC +CCA+F + ++ L 
Sbjct: 1    MSRRKQAKPQHFQSDPEVASLPRRDGDTEKGQPSRPTKSKDAHVCGRCCAEFFELSDLLL 60

Query: 52   HQNACSTDPPVMVIIGGQENPNNSSASSEPRPEGHNNPQVMD--------------TEHS 97
            H+  C+ +  V+++    ENP +   +  P P   N  + M+              +EH+
Sbjct: 61   HKKNCTKNQLVLIV---NENPASPPETFSPSPPPDNPDEQMNDTVNKTDQVDCSDLSEHN 117

Query: 98   NPPDSGSSVPTDPTWGPERRGEESPGHFLVA----ATGTAAGGGGGLILASPKLGATPLP 153
                  S     P       G  S  H   A    ++ +++ GGGG          T LP
Sbjct: 118  GLDREESMEVEAPVANKSGSGTSSGSHSSTAPSSSSSSSSSSGGGGSSSTGTSAITTSLP 177

Query: 154  P----------------------ESTP-APPPPPPPPPPPGVGSGHLNIPLILEELRVLQ 190
                                   +ST  A           G   G L +P ++E+L  LQ
Sbjct: 178  QLGDLTTLGNFSVINSNVIIENLQSTKVAVAQFSQEARCGGASGGKLAVPALMEQLLALQ 237

Query: 191  QRQIHQMQMTEQICRQVLLLGSLGQTVGAPASPSELPGTGTASSTKPLLPLFSPI-KPVQ 249
            Q+QIHQ+Q+ EQI  Q+LLL S  Q    P S S   GT   +S  PL  L S + + + 
Sbjct: 238  QQQIHQLQLIEQIRHQILLLAS--QNADLPTSSSPSQGT-LRTSANPLSTLSSHLSQQLA 294

Query: 250  TSKTLASSSSSSSSS-SGA------ETPKQAFFHLYHPLGSQH-------------PFS- 288
             +  LA S +S S+S SG       + P+ +  +   P  S               P S 
Sbjct: 295  AAAGLAQSLASQSASISGVKQLPPIQLPQSSSGNTIIPSNSGSSPNMNILAAAVTTPSSE 354

Query: 289  --AGGVGRSHKPTPAPSPALPGSTDQLIASPHLAFPSTTGLLAAQCLGAA---------- 336
              A   G SH      +PA+  S+    A   L  P++  LL  Q    +          
Sbjct: 355  KVASSAGASH----VSNPAVSSSSSPAFAISSLLSPASNPLLPQQASANSVFPSPLPNIG 410

Query: 337  ------RGLEATASPGLLKPKNGSGELSYGEVMGPLEKPGGRHKCRFCAKVFGSDSALQI 390
                    L A A     KP N    ++  E     ++   +HKCRFCAKVFGSDSALQI
Sbjct: 411  TTAEDLNSLSALAQQRKSKPPN----VTAFEAKSTSDEAFFKHKCRFCAKVFGSDSALQI 466

Query: 391  HLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPHVQMNPHPVPEHLDYVITSSGL 450
            HLRSHTGERP+KCN+CGNRF+T+GNLKVHF RH+EKYPH+QMNP+PVPEHLD + TS+G+
Sbjct: 467  HLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEHLDNIPTSTGI 526

Query: 451  PYGMSVPPEKAEEE---------AATPGGGVERKPLVASTTALSATESLTLLSTSAGTAT 501
            PYGMS+PPEK               T   G+   P + S      TE    +  S    +
Sbjct: 527  PYGMSIPPEKPVTSWLDTKPVLPTLTTSVGLPLPPTLPSLIPFIKTEEPAPIPISHSATS 586

Query: 502  APGLPAFNKFVLMKAVE-----PKNKADENTPPGSEGSAISGVAESS--TATRMQLSKLV 554
             PG    +      A       P+       PP    S  SG+  +S  TA+   LS   
Sbjct: 587  PPGSVKSDSGGPESATRNLGGLPEEAEGSTLPPSGGKSEESGMVTNSVPTASSSVLSSPA 646

Query: 555  TSL-----------PSWALLTNHFKSTGSFPFPYVLEPLGASPSETSKLQQLVEKIDRQG 603
                          P   L++  FK+   FPF  +L+   A  SETSKLQQLVE ID++ 
Sbjct: 647  ADCGPAGSATTFTNPLLPLMSEQFKA--KFPFGGLLD--SAQASETSKLQQLVENIDKK- 701

Query: 604  AVAVTSAASGAPTTSAPAPSSSASSGPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKV 663
                                   ++ PN+C+IC RVLSC  AL++HY  H GERPFKCK+
Sbjct: 702  -----------------------ATDPNECIICHRVLSCQSALKMHYRTHTGERPFKCKI 738

Query: 664  CGRAFSTRGNLRAHFVGHKASPAARAQNSCPICQKKFTNAVTLQQHVRMHLGGQIPNGGT 723
            CGRAF+T+GNL+ H+  H+A P  R Q+SCPICQKKFTNAV LQQH+RMH+GGQIPN  T
Sbjct: 739  CGRAFTTKGNLKTHYSVHRAMPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPN--T 796

Query: 724  ALPEGGGAAQENGS---EQSTVSGAGSFPQQQSQQPSPEEELSEEEEEEDEEEEEDVT-- 778
             +P+    + E+ +   ++       +F   ++ +  PE  + +  +  D  ++   +  
Sbjct: 797  PVPDSYSESMESDTGSFDEKNFDDLDNF-SDENMEDCPEGSIPDTPKSADASQDSLSSSP 855

Query: 779  ---DEDSLAGRGSE-----SGGEKAISVRGDSEEASGAEEEVGTVAAAATAGKEMDS--- 827
               +  S+A   ++     +G  + +     S E    E +V T  +++  G +M+S   
Sbjct: 856  LPLEMSSIAALENQMKMINAGLAEQLQASLKSVENGSIEGDVLTNDSSSVGG-DMESQSA 914

Query: 828  -----NEKTTQQSSLPPPPPPDSLDQPQPMEQGSSGVLGGKEEGGKPERS--SSPASALT 880
                 +E T+   +L P        +   +E+             KP+R+  S  A+ L+
Sbjct: 915  GSPAISESTSSMQALSPSNSTQEFHKSPSIEE-------------KPQRAVPSEFANGLS 961

Query: 881  P---EGEATSVT------LVEELSLQEAMRKEPGESSSRKACEVCGQAFPSQAALEEHQK 931
            P    G A  +T      +++E SL               AC++CG+ F  Q+AL+ H +
Sbjct: 962  PTPVNGGALDLTSSHAEKIIKEDSLGILFPFRDRGKFKNTACDICGKTFACQSALDIHYR 1021

Query: 932  THPKEGPLFTCVFCRQGFLERATLKKHML------LAHHQVQPFAPHGPQNIAALSLVPG 985
            +H KE P F C  C +GF  +  LK+HML      L     +P +  GP   +A+     
Sbjct: 1022 SHTKERP-FICTVCNRGFSTKGNLKQHMLTHQMRDLPSQLFEPSSNLGPNQNSAVIPANS 1080

Query: 986  CSPSITS-----TGLSPFPRKDDPT 1005
             S  I +       +SP   KD PT
Sbjct: 1081 LSSLIKTEVNGFVHVSPQDSKDTPT 1105



 Score = 76.6 bits (187), Expect = 1e-13
 Identities = 31/52 (59%), Positives = 37/52 (71%)

Query: 372  RHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRH 423
            +H C  C K F S SALQIH R+HTGE+P+ C +CG  FTT+GNLKVH   H
Sbjct: 1133 QHYCNTCGKTFSSSSALQIHERTHTGEKPFACTICGRAFTTKGNLKVHMGTH 1184



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 75/311 (24%), Positives = 113/311 (36%), Gaps = 45/311 (14%)

Query: 220  PASPSELPGTGTASSTKPLLPLFSPIKPVQTSKTLASSSSSSSSSSGAETPKQAFFHLYH 279
            P +P     +  + S+ PL    S I  ++    + ++  +    +  ++ +        
Sbjct: 838  PDTPKSADASQDSLSSSPLPLEMSSIAALENQMKMINAGLAEQLQASLKSVENGSIE--- 894

Query: 280  PLGSQHPFSAGGVGRSHKPTPAPSPALPGSTDQLIA------------------SPHLAF 321
              G      +  VG   +   A SPA+  ST  + A                   P  A 
Sbjct: 895  --GDVLTNDSSSVGGDMESQSAGSPAISESTSSMQALSPSNSTQEFHKSPSIEEKPQRAV 952

Query: 322  PS--TTGLLAAQCLGAARGLEATASPGLLKPKNGSGELSYGEVMGPLEKPGG--RHKCRF 377
            PS    GL      G A  L ++ +  ++K      E S G ++ P    G      C  
Sbjct: 953  PSEFANGLSPTPVNGGALDLTSSHAEKIIK------EDSLG-ILFPFRDRGKFKNTACDI 1005

Query: 378  CAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPHVQMNPHPV 437
            C K F   SAL IH RSHT ERP+ C VC   F+T+GNLK H   H+ +          +
Sbjct: 1006 CGKTFACQSALDIHYRSHTKERPFICTVCNRGFSTKGNLKQHMLTHQMR---------DL 1056

Query: 438  PEHLDYVITSSGLPYGMSVPPEKAEEE--AATPGGGVERKPLVASTTALSATESLTLLST 495
            P  L    ++ G     +V P  +          G V   P  +  T  S   S  L S+
Sbjct: 1057 PSQLFEPSSNLGPNQNSAVIPANSLSSLIKTEVNGFVHVSPQDSKDTPTSHVPSGPLSSS 1116

Query: 496  SAGTATAPGLP 506
            +      P LP
Sbjct: 1117 ATSPVLLPALP 1127



 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 38/110 (34%), Positives = 57/110 (51%), Gaps = 17/110 (15%)

Query: 598  KIDRQGAVAVTSAAS-GAPTTSAPA-PSSSASSGP-------------NQCVICLRVLSC 642
            K +  G V V+   S   PT+  P+ P SS+++ P             + C  C +  S 
Sbjct: 1086 KTEVNGFVHVSPQDSKDTPTSHVPSGPLSSSATSPVLLPALPRRTPKQHYCNTCGKTFSS 1145

Query: 643  PRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGH--KASPAARAQ 690
              AL++H   H GE+PF C +CGRAF+T+GNL+ H   H   ++PA R +
Sbjct: 1146 SSALQIHERTHTGEKPFACTICGRAFTTKGNLKVHMGTHMWNSTPARRGR 1195



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 30/95 (31%), Positives = 43/95 (45%), Gaps = 14/95 (14%)

Query: 869  PERSSSPASALTPEG----EATSVTLVEELSLQEAMRKEPGESSSRKACEVCGQAFPSQA 924
            P+ S    ++  P G     ATS  L+  L         P  +  +  C  CG+ F S +
Sbjct: 1097 PQDSKDTPTSHVPSGPLSSSATSPVLLPAL---------PRRTPKQHYCNTCGKTFSSSS 1147

Query: 925  ALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHM 959
            AL+ H++TH  E P F C  C + F  +  LK HM
Sbjct: 1148 ALQIHERTHTGEKP-FACTICGRAFTTKGNLKVHM 1181



 Score = 38.1 bits (87), Expect = 0.042
 Identities = 30/106 (28%), Positives = 40/106 (37%), Gaps = 11/106 (10%)

Query: 614  APTTSAPAPSSSASSGPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGN 673
            +P  S   P+S   SGP        VL  P   R    QH       C  CG+ FS+   
Sbjct: 1096 SPQDSKDTPTSHVPSGPLSSSATSPVL-LPALPRRTPKQH------YCNTCGKTFSSSSA 1148

Query: 674  LRAHFVGHKASPAARAQNSCPICQKKFTNAVTLQQHVRMHLGGQIP 719
            L+ H   H          +C IC + FT    L+ H+  H+    P
Sbjct: 1149 LQIHERTHTGEKPF----ACTICGRAFTTKGNLKVHMGTHMWNSTP 1190


>gi|189217876 sal-like 1 isoform b [Homo sapiens]
          Length = 1227

 Score =  424 bits (1089), Expect = e-118
 Identities = 319/945 (33%), Positives = 451/945 (47%), Gaps = 167/945 (17%)

Query: 171  GVGSGHLNIPLILEELRVLQQRQIHQMQMTEQICRQVLLLGSLGQTVGAPASPSELPGTG 230
            G   G L +P ++E+L  LQQ+QIHQ+Q+ EQI  Q+LLL S  Q    P S S   GT 
Sbjct: 121  GASGGKLAVPALMEQLLALQQQQIHQLQLIEQIRHQILLLAS--QNADLPTSSSPSQGT- 177

Query: 231  TASSTKPLLPLFSPI-KPVQTSKTLASSSSSSSSS-SGA------ETPKQAFFHLYHPLG 282
              +S  PL  L S + + +  +  LA S +S S+S SG       + P+ +  +   P  
Sbjct: 178  LRTSANPLSTLSSHLSQQLAAAAGLAQSLASQSASISGVKQLPPIQLPQSSSGNTIIPSN 237

Query: 283  SQH-------------PFS---AGGVGRSHKPTPAPSPALPGSTDQLIASPHLAFPSTTG 326
            S               P S   A   G SH      +PA+  S+    A   L  P++  
Sbjct: 238  SGSSPNMNILAAAVTTPSSEKVASSAGASH----VSNPAVSSSSSPAFAISSLLSPASNP 293

Query: 327  LLAAQCLGAA----------------RGLEATASPGLLKPKNGSGELSYGEVMGPLEKPG 370
            LL  Q    +                  L A A     KP N    ++  E     ++  
Sbjct: 294  LLPQQASANSVFPSPLPNIGTTAEDLNSLSALAQQRKSKPPN----VTAFEAKSTSDEAF 349

Query: 371  GRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPHV 430
             +HKCRFCAKVFGSDSALQIHLRSHTGERP+KCN+CGNRF+T+GNLKVHF RH+EKYPH+
Sbjct: 350  FKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHI 409

Query: 431  QMNPHPVPEHLDYVITSSGLPYGMSVPPEKAEEE---------AATPGGGVERKPLVAST 481
            QMNP+PVPEHLD + TS+G+PYGMS+PPEK               T   G+   P + S 
Sbjct: 410  QMNPYPVPEHLDNIPTSTGIPYGMSIPPEKPVTSWLDTKPVLPTLTTSVGLPLPPTLPSL 469

Query: 482  TALSATESLTLLSTSAGTATAPGLPAFNKFVLMKAVE-----PKNKADENTPPGSEGSAI 536
                 TE    +  S    + PG    +      A       P+       PP    S  
Sbjct: 470  IPFIKTEEPAPIPISHSATSPPGSVKSDSGGPESATRNLGGLPEEAEGSTLPPSGGKSEE 529

Query: 537  SGVAESS--TATRMQLSKLVTSL-----------PSWALLTNHFKSTGSFPFPYVLEPLG 583
            SG+  +S  TA+   LS                 P   L++  FK+   FPF  +L+   
Sbjct: 530  SGMVTNSVPTASSSVLSSPAADCGPAGSATTFTNPLLPLMSEQFKA--KFPFGGLLD--S 585

Query: 584  ASPSETSKLQQLVEKIDRQGAVAVTSAASGAPTTSAPAPSSSASSGPNQCVICLRVLSCP 643
            A  SETSKLQQLVE ID++                        ++ PN+C+IC RVLSC 
Sbjct: 586  AQASETSKLQQLVENIDKK------------------------ATDPNECIICHRVLSCQ 621

Query: 644  RALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARAQNSCPICQKKFTNA 703
             AL++HY  H GERPFKCK+CGRAF+T+GNL+ H+  H+A P  R Q+SCPICQKKFTNA
Sbjct: 622  SALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHYSVHRAMPPLRVQHSCPICQKKFTNA 681

Query: 704  VTLQQHVRMHLGGQIPNGGTALPEGGGAAQENGS---EQSTVSGAGSFPQQQSQQPSPEE 760
            V LQQH+RMH+GGQIPN  T +P+    + E+ +   ++       +F   ++ +  PE 
Sbjct: 682  VVLQQHIRMHMGGQIPN--TPVPDSYSESMESDTGSFDEKNFDDLDNF-SDENMEDCPEG 738

Query: 761  ELSEEEEEEDEEEEEDVT-----DEDSLAGRGSE-----SGGEKAISVRGDSEEASGAEE 810
             + +  +  D  ++   +     +  S+A   ++     +G  + +     S E    E 
Sbjct: 739  SIPDTPKSADASQDSLSSSPLPLEMSSIAALENQMKMINAGLAEQLQASLKSVENGSIEG 798

Query: 811  EVGTVAAAATAGKEMDS--------NEKTTQQSSLPPPPPPDSLDQPQPMEQGSSGVLGG 862
            +V T  +++  G +M+S        +E T+   +L P        +   +E+        
Sbjct: 799  DVLTNDSSSVGG-DMESQSAGSPAISESTSSMQALSPSNSTQEFHKSPSIEE-------- 849

Query: 863  KEEGGKPERS--SSPASALTP---EGEATSVT------LVEELSLQEAMRKEPGESSSRK 911
                 KP+R+  S  A+ L+P    G A  +T      +++E SL               
Sbjct: 850  -----KPQRAVPSEFANGLSPTPVNGGALDLTSSHAEKIIKEDSLGILFPFRDRGKFKNT 904

Query: 912  ACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHML------LAHHQ 965
            AC++CG+ F  Q+AL+ H ++H KE P F C  C +GF  +  LK+HML      L    
Sbjct: 905  ACDICGKTFACQSALDIHYRSHTKERP-FICTVCNRGFSTKGNLKQHMLTHQMRDLPSQL 963

Query: 966  VQPFAPHGPQNIAALSLVPGCSPSITS-----TGLSPFPRKDDPT 1005
             +P +  GP   +A+      S  I +       +SP   KD PT
Sbjct: 964  FEPSSNLGPNQNSAVIPANSLSSLIKTEVNGFVHVSPQDSKDTPT 1008



 Score = 76.6 bits (187), Expect = 1e-13
 Identities = 31/52 (59%), Positives = 37/52 (71%)

Query: 372  RHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRH 423
            +H C  C K F S SALQIH R+HTGE+P+ C +CG  FTT+GNLKVH   H
Sbjct: 1036 QHYCNTCGKTFSSSSALQIHERTHTGEKPFACTICGRAFTTKGNLKVHMGTH 1087



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 75/311 (24%), Positives = 113/311 (36%), Gaps = 45/311 (14%)

Query: 220  PASPSELPGTGTASSTKPLLPLFSPIKPVQTSKTLASSSSSSSSSSGAETPKQAFFHLYH 279
            P +P     +  + S+ PL    S I  ++    + ++  +    +  ++ +        
Sbjct: 741  PDTPKSADASQDSLSSSPLPLEMSSIAALENQMKMINAGLAEQLQASLKSVENGSIE--- 797

Query: 280  PLGSQHPFSAGGVGRSHKPTPAPSPALPGSTDQLIA------------------SPHLAF 321
              G      +  VG   +   A SPA+  ST  + A                   P  A 
Sbjct: 798  --GDVLTNDSSSVGGDMESQSAGSPAISESTSSMQALSPSNSTQEFHKSPSIEEKPQRAV 855

Query: 322  PS--TTGLLAAQCLGAARGLEATASPGLLKPKNGSGELSYGEVMGPLEKPGG--RHKCRF 377
            PS    GL      G A  L ++ +  ++K      E S G ++ P    G      C  
Sbjct: 856  PSEFANGLSPTPVNGGALDLTSSHAEKIIK------EDSLG-ILFPFRDRGKFKNTACDI 908

Query: 378  CAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPHVQMNPHPV 437
            C K F   SAL IH RSHT ERP+ C VC   F+T+GNLK H   H+ +          +
Sbjct: 909  CGKTFACQSALDIHYRSHTKERPFICTVCNRGFSTKGNLKQHMLTHQMR---------DL 959

Query: 438  PEHLDYVITSSGLPYGMSVPPEKAEEE--AATPGGGVERKPLVASTTALSATESLTLLST 495
            P  L    ++ G     +V P  +          G V   P  +  T  S   S  L S+
Sbjct: 960  PSQLFEPSSNLGPNQNSAVIPANSLSSLIKTEVNGFVHVSPQDSKDTPTSHVPSGPLSSS 1019

Query: 496  SAGTATAPGLP 506
            +      P LP
Sbjct: 1020 ATSPVLLPALP 1030



 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 38/110 (34%), Positives = 57/110 (51%), Gaps = 17/110 (15%)

Query: 598  KIDRQGAVAVTSAAS-GAPTTSAPA-PSSSASSGP-------------NQCVICLRVLSC 642
            K +  G V V+   S   PT+  P+ P SS+++ P             + C  C +  S 
Sbjct: 989  KTEVNGFVHVSPQDSKDTPTSHVPSGPLSSSATSPVLLPALPRRTPKQHYCNTCGKTFSS 1048

Query: 643  PRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGH--KASPAARAQ 690
              AL++H   H GE+PF C +CGRAF+T+GNL+ H   H   ++PA R +
Sbjct: 1049 SSALQIHERTHTGEKPFACTICGRAFTTKGNLKVHMGTHMWNSTPARRGR 1098



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 30/95 (31%), Positives = 43/95 (45%), Gaps = 14/95 (14%)

Query: 869  PERSSSPASALTPEG----EATSVTLVEELSLQEAMRKEPGESSSRKACEVCGQAFPSQA 924
            P+ S    ++  P G     ATS  L+  L         P  +  +  C  CG+ F S +
Sbjct: 1000 PQDSKDTPTSHVPSGPLSSSATSPVLLPAL---------PRRTPKQHYCNTCGKTFSSSS 1050

Query: 925  ALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHM 959
            AL+ H++TH  E P F C  C + F  +  LK HM
Sbjct: 1051 ALQIHERTHTGEKP-FACTICGRAFTTKGNLKVHM 1084



 Score = 38.1 bits (87), Expect = 0.042
 Identities = 30/106 (28%), Positives = 40/106 (37%), Gaps = 11/106 (10%)

Query: 614  APTTSAPAPSSSASSGPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGN 673
            +P  S   P+S   SGP        VL  P   R    QH       C  CG+ FS+   
Sbjct: 999  SPQDSKDTPTSHVPSGPLSSSATSPVL-LPALPRRTPKQH------YCNTCGKTFSSSSA 1051

Query: 674  LRAHFVGHKASPAARAQNSCPICQKKFTNAVTLQQHVRMHLGGQIP 719
            L+ H   H          +C IC + FT    L+ H+  H+    P
Sbjct: 1052 LQIHERTHTGEKPF----ACTICGRAFTTKGNLKVHMGTHMWNSTP 1093


>gi|10047144 sal-like 4 [Homo sapiens]
          Length = 1053

 Score =  350 bits (897), Expect = 5e-96
 Identities = 310/1039 (29%), Positives = 446/1039 (42%), Gaps = 200/1039 (19%)

Query: 1   MSRRKQRKPQQLISDCE-------------------GPSASE---------NGDASEED- 31
           MSRRKQ KPQ + S+ +                    P+A E         N + + ED 
Sbjct: 1   MSRRKQAKPQHINSEEDQGEQQPQQQTPEFADAAPAAPAAGELGAPVNHPGNDEVASEDE 60

Query: 32  ---------HPQVCAKCCAQFTDPTEFLAHQNACSTDPPVMVIIGGQ-----ENPNNSSA 77
                       VC KCCA+F   +EFL H+  C+ +PPV+++   +     E+ + +  
Sbjct: 61  ATVKRLRREETHVCEKCCAEFFSISEFLEHKKNCTKNPPVLIMNDSEGPVPSEDFSGAVL 120

Query: 78  SSEPRPEG----HNNPQVMDTEHSNPPDSGSSV--PTDPTWGPERRGEESPGHFLVAATG 131
           S +P   G    H        +    PD+ S V   T+    P      +P      A G
Sbjct: 121 SHQPTSPGSKDCHRENGGSSEDMKEKPDAESVVYLKTETALPP------TPQDISYLAKG 174

Query: 132 TAAGGGGGL-ILASPKLGATPLPPESTPAPPPPPPPPPPPGVGSGHLNIPLILEELRVLQ 190
             A     L  L   K+       ++ PAP P            G  +IP +LE++  LQ
Sbjct: 175 KVANTNVTLQALRGTKVAVNQRSADALPAPVP------------GANSIPWVLEQILCLQ 222

Query: 191 QRQIHQMQMTEQICRQVLLLGSLGQTVGAPASPSELPGTGTASSTKPLLPLFSPIKPVQT 250
           Q+Q+ Q+Q+TEQI  QV +  S             L  +G  + T  L  L S +    +
Sbjct: 223 QQQLQQIQLTEQIRIQVNMWAS-----------HALHSSGAGADT--LKTLGSHMSQQVS 269

Query: 251 SKTLASSSSSSSSSSGAETPKQAFFHLYHPLGSQHPFSAGGVGRSHKPTPAPSPALPGST 310
           +     S  + S     +  KQA     +   +    S G    + KP    +  LP   
Sbjct: 270 AAVALLSQKAGSQGLSLDALKQAKLPHANIPSATSSLSPGLAPFTLKPD--GTRVLPNVM 327

Query: 311 DQLIASPHLAFPSTTGLLAAQCLGAARGLEATASPGLLKPKNGSGELSYGEVMGPLEKPG 370
            +L   P    P   G +  Q   +   L+ T+  G  KP N    +S  +V    E   
Sbjct: 328 SRL---PSALLPQAPGSVLFQSPFSTVALD-TSKKGKGKPPN----ISAVDVKPKDEAAL 379

Query: 371 GRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPHV 430
            +HKC++C+KVFG+DS+LQIHLRSHTGERP+ C+VCG+RFTT+GNLKVHFHRH    P V
Sbjct: 380 YKHKCKYCSKVFGTDSSLQIHLRSHTGERPFVCSVCGHRFTTKGNLKVHFHRH----PQV 435

Query: 431 QMNPHPVPEHLDYVITSSGLPYGMSVPPEKAEEEAATPGGGVERKPLVASTTALSATESL 490
           + NP    E  D V   +G+PY +SVP    E     P   ++ KP++  TT++   ++L
Sbjct: 436 KANPQLFAEFQDKVAAGNGIPYALSVPDPIDE-----PSLSLDSKPVLV-TTSVGLPQNL 489

Query: 491 TLLSTSAGTATAPGLPAFNKFVLMKAVEPKNKADENTPPGSEGSAISGVAESSTATRMQL 550
                S+GT         N   L     P +     +P    G  + GV  +  + R   
Sbjct: 490 -----SSGT---------NPKDLTGGSLPGDLQPGPSPESEGGPTLPGVGPNYNSPR--- 532

Query: 551 SKLVTSLPSWALLTNHFKSTGSFPFPYVLEPLGASPSETSKLQQLVEKIDRQGAVAVTSA 610
                           F+ +G+ P P          SET KLQQLVE ID+         
Sbjct: 533 -------------AGGFQGSGT-PEP---------GSETLKLQQLVENIDK--------- 560

Query: 611 ASGAPTTSAPAPSSSASSGPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFST 670
                          A++ PN+C+IC RVLSC  +L++HY  H GERPF+CK+CGRAFST
Sbjct: 561 ---------------ATTDPNECLICHRVLSCQSSLKMHYRTHTGERPFQCKICGRAFST 605

Query: 671 RGNLRAHFVGHKASPAARAQNSCPICQKKFTNAVTLQQHVRMHLGGQIPNGGTALPEGGG 730
           +GNL+ H   H+ + + + Q+SCPICQKKFTNAV LQQH+RMH+GGQIPN  T LPE   
Sbjct: 606 KGNLKTHLGVHRTNTSIKTQHSCPICQKKFTNAVMLQQHIRMHMGGQIPN--TPLPE--N 661

Query: 731 AAQENGSEQSTV---SGAGSFPQQQSQQPSPEEELSEEEEEEDEEEEEDVTDE------- 780
                GSE  TV      G+       +    EE+S +E      +              
Sbjct: 662 PCDFTGSEPMTVGENGSTGAICHDDVIESIDVEEVSSQEAPSSSSKVPTPLPSIHSASPT 721

Query: 781 ------DSLAGRGSESGGEKAISVRGDSEEASGAEEEVGTVAAAATAGKEMDSN-----E 829
                  SL   G        +  +G  E  S   + +   +++    +E  S      E
Sbjct: 722 LGFAMMASLDAPGKVGPAPFNLQRQGSRENGSVESDGLTNDSSSLMGDQEYQSRSPDILE 781

Query: 830 KTTQQSSLPPPPPPDSLDQPQPMEQGSSGVLGGKEEGGKPERSSSPASALTPEGEATSV- 888
            T+ Q+  P     +S+    P + GS              RSS P++ +        V 
Sbjct: 782 TTSFQALSPANSQAESIKSKSP-DAGSKAESSENSRTEMEGRSSLPSTFIRAPPTYVKVE 840

Query: 889 ---TLVEELSLQEAM----RKEPGESSSRKACEVCGQAFPSQAALEEHQKTHPKEGPLFT 941
              T V   +L   M      +P   + +  C  CG+ F S +AL+ H++TH  E P F 
Sbjct: 841 VPGTFVGPSTLSPGMTPLLAAQPRRQAKQHGCTRCGKNFSSASALQIHERTHTGEKP-FV 899

Query: 942 CVFCRQGFLERATLKKHML 960
           C  C + F  +  LK H +
Sbjct: 900 CNICGRAFTTKGNLKVHYM 918



 Score =  104 bits (260), Expect = 4e-22
 Identities = 97/389 (24%), Positives = 161/389 (41%), Gaps = 61/389 (15%)

Query: 350 PKNGSGELSYGEVMGPLEKPG-GRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGN 408
           P+ GS  L   +++  ++K     ++C  C +V    S+L++H R+HTGERP++C +CG 
Sbjct: 542 PEPGSETLKLQQLVENIDKATTDPNECLICHRVLSCQSSLKMHYRTHTGERPFQCKICGR 601

Query: 409 RFTTRGNLKVHFHRHR---------------EKYPHVQMNPHPVPEHLDYVITSSGLPYG 453
            F+T+GNLK H   HR               +K+ +  M    +  H+   I ++ LP  
Sbjct: 602 AFSTKGNLKTHLGVHRTNTSIKTQHSCPICQKKFTNAVMLQQHIRMHMGGQIPNTPLPEN 661

Query: 454 MSVPPEKAEEEAATPG-----GGVERKPLVASTTALSATESLTLLSTSAGTATAPGLPAF 508
              P +    E  T G     G +    ++ S      +      S+S      P + + 
Sbjct: 662 ---PCDFTGSEPMTVGENGSTGAICHDDVIESIDVEEVSSQEAPSSSSKVPTPLPSIHSA 718

Query: 509 NK---FVLMKAVEPKNKADENTPPGS---EGSAISGVAESSTATRMQLSKL----VTSLP 558
           +    F +M +++   K      P +   +GS  +G  ES   T    S +      S  
Sbjct: 719 SPTLGFAMMASLDAPGKV--GPAPFNLQRQGSRENGSVESDGLTNDSSSLMGDQEYQSRS 776

Query: 559 SWALLTNHFKSTGSFPFPYVLEPLGA-SPSETSKLQQLVE-KIDRQGAVAVTSAASGAPT 616
              L T  F++    P     E + + SP   SK +     + + +G  ++ S    AP 
Sbjct: 777 PDILETTSFQALS--PANSQAESIKSKSPDAGSKAESSENSRTEMEGRSSLPSTFIRAPP 834

Query: 617 TSAPAPSSSASSGPNQ---------------------CVICLRVLSCPRALRLHYGQHGG 655
           T           GP+                      C  C +  S   AL++H   H G
Sbjct: 835 TYVKVEVPGTFVGPSTLSPGMTPLLAAQPRRQAKQHGCTRCGKNFSSASALQIHERTHTG 894

Query: 656 ERPFKCKVCGRAFSTRGNLRAHFVGHKAS 684
           E+PF C +CGRAF+T+GNL+ H++ H A+
Sbjct: 895 EKPFVCNICGRAFTTKGNLKVHYMTHGAN 923



 Score = 77.8 bits (190), Expect = 5e-14
 Identities = 55/175 (31%), Positives = 79/175 (45%), Gaps = 10/175 (5%)

Query: 372  RHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPHVQ 431
            +H C  C K F S SALQIH R+HTGE+P+ CN+CG  FTT+GNLKVH+  H       +
Sbjct: 869  QHGCTRCGKNFSSASALQIHERTHTGEKPFVCNICGRAFTTKGNLKVHYMTHGANNNSAR 928

Query: 432  MNPHPVPEHLDYVITSSGLPYGMSVPPEKAEEEAATPGGGVERKPLVASTTALSATESLT 491
                   E+   ++ + G       P     +E   P   V+  P+V +         L 
Sbjct: 929  RGRKLAIENTMALLGTDGKRVSEIFP-----KEILAPSVNVD--PVVWNQYTSMLNGGLA 981

Query: 492  LLSTSAGTATAPGLPAFNKFVLMKAVEPKNKADENTPPGSEGSAISGVAESSTAT 546
            + +       + G+P     V + A    N A  +   GS+ S IS   E  +AT
Sbjct: 982  VKTNEISVIQSGGVPTLP--VSLGATSVVNNATVSKMDGSQ-SGISADVEKPSAT 1033


>gi|138175817 zinc finger protein 236 [Homo sapiens]
          Length = 1845

 Score =  109 bits (272), Expect = 1e-23
 Identities = 149/658 (22%), Positives = 239/658 (36%), Gaps = 117/658 (17%)

Query: 373  HKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRH--------- 423
            +KC +C + +     L+ H+RSHTGE+P+KC+ CG  F + G LK H   H         
Sbjct: 657  YKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCL 716

Query: 424  -------------REKYPHVQMNPHPVPEHLDYVITSSGLP-------YGMSVPPEKAEE 463
                         R    H  + P+  P       TS           Y ++   ++ ++
Sbjct: 717  ICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQQ 776

Query: 464  EAATPGGGVERKPLVASTTALSATESLTLLSTSAGTATAPG--LPAFNKFVL-------- 513
             A+     V+++ + AST      ES  L  T+   A  P   L    + V+        
Sbjct: 777  AASIDDSTVDQQSMQASTQMQVEIESDELPQTAEVVAANPEAMLDLEPQHVVGTEEAGLG 836

Query: 514  MKAVEPKNKADENTPPGSEGSAISGVAESSTATRMQLSKLVTSLPSWALLTNHFKSTGSF 573
             +  +   +ADE+     +      V +    +  Q S     LP    +T+ +     F
Sbjct: 837  QQLADQPLEADEDGFVAPQDPLRGHVDQFEEQSPAQQSFEPAGLPQGFTVTDTYHQQPQF 896

Query: 574  PFPYVLEPLGASPSETSKLQQLVEKIDRQGAVAVTSAASGAPTTSAPAPSS--------- 624
            P    L+      S T + Q L     +Q  +   S+     TT     SS         
Sbjct: 897  PPVQQLQ-----DSSTLESQALSTSFHQQSLLQAPSSDGMNVTTRLIQESSQEELDLQAQ 951

Query: 625  ---------SASSGPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLR 675
                       S    +C  C +       L+ H   H GE+P+KCK+CGR F + G L+
Sbjct: 952  GSQFLEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLK 1011

Query: 676  AHFVGHKASPAARAQNSCPICQKKFTNAVTLQQHVRMHLGGQIPNGGTALPEGGGAAQEN 735
            +H   H    A     SC +C   FT   +L +H+  H+  + P       EG       
Sbjct: 1012 SHEKTHTGVKAF----SCSVCNASFTTNGSLTRHMATHMSMK-PYKCPFCEEG------- 1059

Query: 736  GSEQSTVSGAGSFPQQQSQQPSPEEELSEEEEEEDEEEEEDVTDEDSLAGRGSESGGEKA 795
               ++TV       + Q+   +       E  +   EEEE+ +D ++             
Sbjct: 1060 --FRTTVHCKKHMKRHQTVPSAVSATGETEGGDICMEEEEEHSDRNA------------- 1104

Query: 796  ISVRGDSEEASGAEEEVGTVAAAATAGKEMDSNEKTTQQSSLPPPPPPDSLDQPQPMEQG 855
             S +   E  +  EEE   +A      +    +EK   QS+                E+ 
Sbjct: 1105 -SRKSRPEVITFTEEETAQLAKIRPQ-ESATVSEKVLVQSA---------------AEKD 1147

Query: 856  SSGVLGGKEEGGKPERSSSPASALTPEGEATSVTLVEELSLQEAMRKEPGESSSRKACEV 915
                L  K+   + E   +      P+       LV        +R   GE   +  C+ 
Sbjct: 1148 RISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRH------VRIHTGEKPYK--CDE 1199

Query: 916  CGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAHHQVQPF-APH 972
            CG++F  ++ L+ H KTH  +  LF+C  C   F  + +LK HM L H   +PF  PH
Sbjct: 1200 CGKSFTVKSTLDCHVKTHTGQ-KLFSCHVCSNAFSTKGSLKVHMRL-HTGAKPFKCPH 1255



 Score =  103 bits (258), Expect = 6e-22
 Identities = 99/385 (25%), Positives = 152/385 (39%), Gaps = 47/385 (12%)

Query: 366 LEKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHRE 425
           +++ G  + C  C K F   S L  H+R HTGERP+KC+ CG  F  +G L+ H  +H  
Sbjct: 190 IDRSGFTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTG 249

Query: 426 KYP------------------HVQMNPHPVPEHLDYVITSSGLPYGMSVPPEKAEEEAAT 467
           + P                  HVQ     V     Y  T     +  S+           
Sbjct: 250 EKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVF-KSLGSLNTHISKMH 308

Query: 468 PGGGVERKPLVASTTALSAT--ESLTLLSTSAGTATAPGLPAFNKF-----VLMKAVEPK 520
            GG         +   L+AT  ++L L  T A   +A   P+          L++  EP 
Sbjct: 309 MGGPQNSTSSTETAHVLTATLFQTLPLQQTEAQATSASSQPSSQAVSDVIQQLLELSEPA 368

Query: 521 NKADENTP-PGSEGSAISGVAESSTATRMQLSKLVTSLPSWALLTNHFKSTGSFPF---P 576
                 +P PG + S   G+ +      ++ S L +S+P+ A   +   +  S P    P
Sbjct: 369 PVESGQSPQPGQQLSITVGINQDILQQALENSGL-SSIPAAAHPNDSCHAKTSAPHAQNP 427

Query: 577 YVL----EPLGASPSETSKLQQLVEKIDRQGAVAVTSAASGAPTTSAPAPSSSASSGP-- 630
            V     E    + +E  K Q+  EK+D++    +   +   P       S    +G   
Sbjct: 428 DVSSVSNEQTDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLP------GSIREENGVRW 481

Query: 631 NQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARAQ 690
           + C  C +    P  L  H   H  E+PFKC  C RAF+ +  L AH   H    A +  
Sbjct: 482 HVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGIKAFK-- 539

Query: 691 NSCPICQKKFTNAVTLQQHVRMHLG 715
             C  C K F+ + +L+ H+R+H G
Sbjct: 540 --CQYCMKSFSTSGSLKVHIRLHTG 562



 Score = 83.6 bits (205), Expect = 9e-16
 Identities = 95/380 (25%), Positives = 150/380 (39%), Gaps = 48/380 (12%)

Query: 633 CVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARAQNS 692
           C  C +    P  L  H   H GERPFKC  CG+AF+ +G L+ H + H         ++
Sbjct: 199 CPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKH----TGEKPHA 254

Query: 693 CPICQKKFTNAVTLQQHV-RMHLGGQIPNGGT---------------------ALPEGGG 730
           C  C   F+    LQ HV R+H   ++ NG T                      +  GG 
Sbjct: 255 CAFCPAAFSQKGNLQSHVQRVH--SEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGP 312

Query: 731 AAQENGSEQSTVSGAGSF-----PQQQSQQPSPEEELSEEEEEEDEEEEEDVTDEDSL-A 784
               + +E + V  A  F      Q ++Q  S   + S +   +  ++  ++++   + +
Sbjct: 313 QNSTSSTETAHVLTATLFQTLPLQQTEAQATSASSQPSSQAVSDVIQQLLELSEPAPVES 372

Query: 785 GRGSESGGEKAISVRGDSEEASGAEEEVGTVAAAATAGKEMDSNEKTTQQSSLPPP---- 840
           G+  + G + +I+V  + +    A E  G  +  A A      + KT+   +  P     
Sbjct: 373 GQSPQPGQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSV 432

Query: 841 --PPPDSLDQPQPMEQGSSGVLGGKEEGGKPERSS-SPASALTPEGEATSVT--LVEELS 895
                D  D  Q  EQ S   L  KE+    ++S   P S     G    V     +E  
Sbjct: 433 SNEQTDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFR 492

Query: 896 LQEAMRKEPGESSSRK--ACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERA 953
               + +     +  K   C  C +AF  ++ L  H KTH      F C +C + F    
Sbjct: 493 KPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTHTGI-KAFKCQYCMKSFSTSG 551

Query: 954 TLKKHMLLAHHQVQPFA-PH 972
           +LK H+ L H  V+PFA PH
Sbjct: 552 SLKVHIRL-HTGVRPFACPH 570



 Score = 82.8 bits (203), Expect = 1e-15
 Identities = 89/412 (21%), Positives = 145/412 (35%), Gaps = 88/412 (21%)

Query: 630  PNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARA 689
            P +C  C R       L+ H   H GE+PFKC  CGR F + G L+AH   H    + + 
Sbjct: 656  PYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKC 715

Query: 690  ------------------------QNSCPICQKKFTNAVTLQQHVRMHLGGQIPNGGTAL 725
                                       CP CQK F  ++  ++H++ H            
Sbjct: 716  LICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYE--------- 766

Query: 726  PEGGGAAQENGSEQSTVSGAGSFPQQQSQQPSPEEELSEEEEEEDEEEEEDVTDEDSLAG 785
                  AQ+    Q   S   S   QQS Q S + ++  E +E  +  E    + +++  
Sbjct: 767  -----LAQQLQQHQQAASIDDSTVDQQSMQASTQMQVEIESDELPQTAEVVAANPEAMLD 821

Query: 786  RGSES--GGEKAISVRGDSEEASGAEEEVGTVAAAATAGKEMDSNEKTTQQSSLPPPPPP 843
               +   G E+A   +  +++   A+E+          G      E++  Q S  P   P
Sbjct: 822  LEPQHVVGTEEAGLGQQLADQPLEADEDGFVAPQDPLRGHVDQFEEQSPAQQSFEPAGLP 881

Query: 844  DSL-------DQPQ--PMEQGSSGVLGGKEEGGKPERSSSPASALTPEGEATSVTLVEEL 894
                       QPQ  P++Q         +         S   A + +G   +  L++E 
Sbjct: 882  QGFTVTDTYHQQPQFPPVQQLQDSSTLESQALSTSFHQQSLLQAPSSDGMNVTTRLIQES 941

Query: 895  SLQE-------AMRKEPGESSSRKA------------------------------CEVCG 917
            S +E       +   E  E  SR++                              C++CG
Sbjct: 942  SQEELDLQAQGSQFLEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCG 1001

Query: 918  QAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAHHQVQPF 969
            + F S   L+ H+KTH      F+C  C   F    +L +HM   H  ++P+
Sbjct: 1002 RGFVSSGVLKSHEKTHTGV-KAFSCSVCNASFTTNGSLTRHM-ATHMSMKPY 1051



 Score = 75.5 bits (184), Expect = 2e-13
 Identities = 102/448 (22%), Positives = 157/448 (35%), Gaps = 52/448 (11%)

Query: 353  GSGELSYGEVMGPLEKPGG--RHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRF 410
            G G +S G +   +    G    KC  C   F +  +L+ H+  H   RPY C  C   F
Sbjct: 691  GRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTF 750

Query: 411  TTRGNLKVHFHRHREKYPHVQMNPHPVPEHLD---------YVITSSGLPYGMSVPPEKA 461
             T  N K H   HR +    Q+  H     +D            T   +       P+ A
Sbjct: 751  KTSLNCKKHMKTHRYELAQ-QLQQHQQAASIDDSTVDQQSMQASTQMQVEIESDELPQTA 809

Query: 462  EEEAATPGGGVERKPL-VASTTALSATESLT--LLSTSAGTATAPGLPAFNKFVLMKAVE 518
            E  AA P   ++ +P  V  T      + L    L        AP  P        +   
Sbjct: 810  EVVAANPEAMLDLEPQHVVGTEEAGLGQQLADQPLEADEDGFVAPQDPLRGHVDQFEEQS 869

Query: 519  PKNKADENTPPG-SEGSAISG----------VAESSTATRMQLSKLVTSLPSWALLTNHF 567
            P  ++ E  P G  +G  ++           V +   ++ ++   L TS    +LL    
Sbjct: 870  PAQQSFE--PAGLPQGFTVTDTYHQQPQFPPVQQLQDSSTLESQALSTSFHQQSLL---- 923

Query: 568  KSTGSFPFPYVLEPLGASPSETSKLQ----QLVEKIDRQG--AVAVTSAASGAPTTSAPA 621
            ++  S         +  S  E   LQ    Q +E  + Q   +        G   +S   
Sbjct: 924  QAPSSDGMNVTTRLIQESSQEELDLQAQGSQFLEDNEDQSRRSYRCDYCNKGFKKSSHLK 983

Query: 622  PSSSASSG--PNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFV 679
                + +G  P +C +C R       L+ H   H G + F C VC  +F+T G+L  H  
Sbjct: 984  QHVRSHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCSVCNASFTTNGSLTRHMA 1043

Query: 680  GHKASPAARAQNSCPICQKKFTNAVTLQQHVRMHLGGQIPNGGTALPEGGGAAQENGSEQ 739
             H +    +    CP C++ F   V  ++H++ H         T   EGG    E   E 
Sbjct: 1044 THMSMKPYK----CPFCEEGFRTTVHCKKHMKRHQTVPSAVSATGETEGGDICMEEEEEH 1099

Query: 740  STVSGAGSFPQQQSQQPSPEEELSEEEE 767
            S         +  S++  PE     EEE
Sbjct: 1100 S--------DRNASRKSRPEVITFTEEE 1119



 Score = 67.8 bits (164), Expect = 5e-11
 Identities = 125/612 (20%), Positives = 219/612 (35%), Gaps = 94/612 (15%)

Query: 375  CRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPHVQMNP 434
            C  C+  F +  +L++H+R HTG +P+KC  C  RF T G  K H   H +  P     P
Sbjct: 1225 CHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDPKKARKP 1284

Query: 435  HPVP-----EHLDYVITSSGLP----YGMSVPPEKAEEEAATPGGGVERKPLVASTTALS 485
                     + ++ + +SS  P       SV   + ++    PG  V +  L AS   +S
Sbjct: 1285 MTRSSSEGLQPVNLLNSSSTDPNVFIMNNSVLTGQFDQNLLQPGL-VGQAILPAS---VS 1340

Query: 486  ATESLTLLSTSAGTATAPGLPAFNKFVLMKAVEPKNKADENTPPGSEGSAISGVAESSTA 545
            A   LT+  T    AT  G+      +    V P  +       G + ++I+ +      
Sbjct: 1341 AGGDLTVSLTDGSLATLEGIQLQ---LAANLVGPNVQIS-----GIDAASINNITLQIDP 1392

Query: 546  TRMQ--------LSKLVTSLPSWALLTNHFKSTGS-FPFPYVLEP---LGASPSETSKLQ 593
            + +Q        L++ +T  P  A   +  +++ S  P   V++P   L   P+ TS   
Sbjct: 1393 SILQQTLQQGNLLAQQLTGEPGLAPQNSSLQTSDSTVPASVVIQPISGLSLQPTVTSA-N 1451

Query: 594  QLVEKIDRQGAVAVTSAASGAPTTSAPAPSS--SASSGPNQCVICLRVLSCPRALRLHYG 651
              +  +  Q +V  T+++     T         S S GP++  + +   S  + L     
Sbjct: 1452 LTIGPLSEQDSVLTTNSSGTQDLTQVMTSQGLVSPSGGPHEITLTINNSSLSQVL----- 1506

Query: 652  QHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARAQNSCPICQKKFTNAVTLQQHVR 711
                                           A P A + +  P         +TL     
Sbjct: 1507 ----------------------------AQAAGPTATSSSGSP-------QEITLTISEL 1531

Query: 712  MHLGGQIPNGGTALPEGGGAAQENGSEQSTVSGAGS----FPQQQSQQPSPEEELSEEEE 767
                G +P+  T +     + Q      S V G  S        Q       + ++    
Sbjct: 1532 NTTSGSLPST-TPMSPSAISTQNLVMSSSGVGGDASVTLTLADTQGMLSGGLDTVTLNIT 1590

Query: 768  EEDEEEEEDVTDEDSLAGRGSESGGEKAISVRGDSEEASGAEEEVGTVAAAATAGKEMDS 827
             + ++    +TD  SL+G+G  +G  + I V    + AS A EE+     A  +G     
Sbjct: 1591 SQGQQFPALLTDP-SLSGQGG-AGSPQVILVSHTPQSASAACEEIA-YQVAGVSGNLAPG 1647

Query: 828  NEKTTQQSSLPPPPPPDSLDQPQPMEQGSSGVLGGKEEGGKPERSSSPASALTPEGEATS 887
            N+   +  +         L+  +     +  +   KE  G+      P      +    +
Sbjct: 1648 NQPEKEGRA------HQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCR---KAFKRA 1698

Query: 888  VTLVEELSLQEAMRKEPGESSSRKACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQ 947
              L E +   +A      +      C+ C +AF   + LE H + H  E P F C  C +
Sbjct: 1699 THLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERP-FHCTLCEK 1757

Query: 948  GFLERATLKKHM 959
             F +++ L+ HM
Sbjct: 1758 AFNQKSALQVHM 1769



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 25/48 (52%), Positives = 31/48 (64%)

Query: 375  CRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHR 422
            C  C K F   SALQ+H++ HTGERPYKC  C   FT + N+K+H  R
Sbjct: 1752 CTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMKR 1799



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 53/176 (30%), Positives = 80/176 (45%), Gaps = 39/176 (22%)

Query: 367  EKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREK 426
            EKP   +KC  C K F   S L  H+++HTG++ + C+VC N F+T+G+LKVH       
Sbjct: 1192 EKP---YKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRL---- 1244

Query: 427  YPHVQMNPHPVPEHLDYVITSSG-----LPYGMSVPPEKAEEEAATPGGGVERKPLVAST 481
              H    P   P H +    +SG     + +     P+KA            RKP+  S+
Sbjct: 1245 --HTGAKPFKCP-HCELRFRTSGRRKTHMQFHYKPDPKKA------------RKPMTRSS 1289

Query: 482  TALSATESLTLLSTSAGTATAPGLPAFNKFVLMKAVEPKNKADEN-TPPGSEGSAI 536
            +     + + LL++S   +T P +   N  VL        + D+N   PG  G AI
Sbjct: 1290 S--EGLQPVNLLNSS---STDPNVFIMNNSVL------TGQFDQNLLQPGLVGQAI 1334



 Score = 57.0 bits (136), Expect = 9e-08
 Identities = 24/57 (42%), Positives = 32/57 (56%)

Query: 367  EKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRH 423
            ++P   + C +C K F   S L  H+R HTGE+PYKC+ CG  FT +  L  H   H
Sbjct: 1161 DEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTH 1217



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 21/50 (42%), Positives = 31/50 (62%)

Query: 374 KCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRH 423
           KC++C K F +  +L++H+R HTG RP+ C  C  +F T G+ K H   H
Sbjct: 539 KCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASH 588



 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 23/56 (41%), Positives = 31/56 (55%)

Query: 374  KCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPH 429
            KC  C K F   S L+ H R HTGERP+ C +C   F  +  L+VH  +H  + P+
Sbjct: 1723 KCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERPY 1778



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 23/81 (28%), Positives = 39/81 (48%)

Query: 633 CVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARAQNS 692
           C +C +  S   +L+ H   H  E    C  CG  F+ +  L  H   H+   A   Q++
Sbjct: 95  CPVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQHA 154

Query: 693 CPICQKKFTNAVTLQQHVRMH 713
           C  C+K+F  +  L++H++ H
Sbjct: 155 CKACKKEFETSSELKEHMKTH 175



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 25/84 (29%), Positives = 41/84 (48%), Gaps = 4/84 (4%)

Query: 630  PNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARA 689
            P +C  C +  +    L  H   H G++ F C VC  AFST+G+L+ H   H  +   + 
Sbjct: 1194 PYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFK- 1252

Query: 690  QNSCPICQKKFTNAVTLQQHVRMH 713
               CP C+ +F  +   + H++ H
Sbjct: 1253 ---CPHCELRFRTSGRRKTHMQFH 1273



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 30/109 (27%), Positives = 47/109 (43%), Gaps = 9/109 (8%)

Query: 632  QCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARAQN 691
            +C  C +  + P  L  H   H GERPF C +C +AF+ +  L+ H   H          
Sbjct: 1723 KCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKH----TGERPY 1778

Query: 692  SCPICQKKFTNAVTLQQHVRMHLGGQIPNGGTALPEGGGAAQENGSEQS 740
             C  C   FT    ++ H++     +  +   AL E  G  +++G E S
Sbjct: 1779 KCAYCVMGFTQKSNMKLHMK-----RAHSYAGALQESAGHPEQDGEELS 1822



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 78/408 (19%), Positives = 125/408 (30%), Gaps = 82/408 (20%)

Query: 633 CVICLRVLSCPRALRLHYGQH----GGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAAR 688
           C  C    +    L +H  +H     G R   CK C + F T   L+ H   H     + 
Sbjct: 123 CSECGDEFTLQSQLAVHMEEHRQELAGTRQHACKACKKEFETSSELKEHMKTHYKIRVSS 182

Query: 689 AQN------------SCPICQKKFTNAVTLQQHVRMHLGG---QIPNGGTALPEGGGAAQ 733
            ++            SCP C K F     L +H+R+H G    +    G A  + G    
Sbjct: 183 TRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQT 242

Query: 734 ENGSEQSTVSGAGSF-PQQQSQQPSPEEELSEEEEEEDEEEEEDVTDEDSL-AGRGSESG 791
                      A +F P   SQ+ + +  +     E       + T+   +    GS + 
Sbjct: 243 HMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNT 302

Query: 792 GEKAISVRGDSEEASGAEE------------EVGTVAAAATAGKEMDSNEKTT----QQS 835
               + + G     S  E              +    A AT+     S++  +    Q  
Sbjct: 303 HISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQTEAQATSASSQPSSQAVSDVIQQLL 362

Query: 836 SLPPPPPPDSLDQPQPMEQ-------------------GSSGVLGGKEEGGKPERSSSPA 876
            L  P P +S   PQP +Q                   G S +             +S  
Sbjct: 363 ELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKTSAP 422

Query: 877 SALTPEGEATSVTLVEELSLQEAMRKEPGESSSRK------------------------- 911
            A  P+  + S    +    ++   +E  E   +K                         
Sbjct: 423 HAQNPDVSSVSNEQTDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWH 482

Query: 912 ACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHM 959
            C  C + F   + L  H + H  E P F C  C + F  ++TL  H+
Sbjct: 483 VCPYCAKEFRKPSDLVRHIRIHTHEKP-FKCPQCFRAFAVKSTLTAHI 529



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 23/84 (27%), Positives = 38/84 (45%), Gaps = 6/84 (7%)

Query: 631 NQCVICLRVLSCPRALRLHYGQHG-GERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARA 689
           ++C ICL         + H   H   ++P +C  C + F+   NL  H   H        
Sbjct: 37  HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP--- 93

Query: 690 QNSCPICQKKFTNAVTLQQHVRMH 713
             +CP+C KKF+   +L+ H+ +H
Sbjct: 94  --TCPVCNKKFSRVASLKAHIMLH 115



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 26/72 (36%), Positives = 39/72 (54%), Gaps = 4/72 (5%)

Query: 913  CEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAHH---QVQPF 969
            C +C +AF  ++AL+ H K H  E P + C +C  GF +++ +K HM  AH     +Q  
Sbjct: 1752 CTLCEKAFNQKSALQVHMKKHTGERP-YKCAYCVMGFTQKSNMKLHMKRAHSYAGALQES 1810

Query: 970  APHGPQNIAALS 981
            A H  Q+   LS
Sbjct: 1811 AGHPEQDGEELS 1822



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 17/48 (35%), Positives = 28/48 (58%)

Query: 630  PNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAH 677
            P  C +C +  +   AL++H  +H GERP+KC  C   F+ + N++ H
Sbjct: 1749 PFHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLH 1796



 Score = 43.9 bits (102), Expect = 8e-04
 Identities = 17/50 (34%), Positives = 26/50 (52%)

Query: 632 QCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGH 681
           +C  C++  S   +L++H   H G RPF C  C + F T G+ + H   H
Sbjct: 539 KCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASH 588



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 18/52 (34%), Positives = 27/52 (51%)

Query: 375 CRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREK 426
           C  C K F   ++L+ H+  H  E    C+ CG+ FT +  L VH   HR++
Sbjct: 95  CPVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQE 146



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 19/57 (33%), Positives = 28/57 (49%), Gaps = 1/57 (1%)

Query: 373 HKCRFCAKVFGSDSALQIHLRSH-TGERPYKCNVCGNRFTTRGNLKVHFHRHREKYP 428
           HKC  C   F  +S  Q H+R H   ++P++C+ C   F    NL +H   H  + P
Sbjct: 37  HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP 93



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 63/295 (21%), Positives = 97/295 (32%), Gaps = 70/295 (23%)

Query: 170  PGVGSGHLNIPLILEELRVLQQRQIHQMQMTEQICRQVLLL--------------GSLGQ 215
            P V S +L I  + E+  VL         +T+ +  Q L+                SL Q
Sbjct: 1445 PTVTSANLTIGPLSEQDSVLTTNSSGTQDLTQVMTSQGLVSPSGGPHEITLTINNSSLSQ 1504

Query: 216  TVGAPASPSELPGTGTA----------SSTKPLLPLFSPIKP--VQTSKTLASSSSSSSS 263
             +   A P+    +G+           ++T   LP  +P+ P  + T   + SSS     
Sbjct: 1505 VLAQAAGPTATSSSGSPQEITLTISELNTTSGSLPSTTPMSPSAISTQNLVMSSSGVGGD 1564

Query: 264  SSGAETPKQAFFHLYHPLGSQHPFSAGGVGR---------SHKPTPAPSPALPGS----T 310
            +S   T           L       +GG+              P     P+L G     +
Sbjct: 1565 ASVTLT-----------LADTQGMLSGGLDTVTLNITSQGQQFPALLTDPSLSGQGGAGS 1613

Query: 311  DQLIASPHLAFPSTTGLLAAQCLGAARGLEATASPGLLKPKNGSGELSYGEVMGPLEKPG 370
             Q+I   H   P +      +      G+    +PG                    EK G
Sbjct: 1614 PQVILVSHT--PQSASAACEEIAYQVAGVSGNLAPG-----------------NQPEKEG 1654

Query: 371  GRHKCRFCAKVFGSDSALQIHLRS-HTGERPYKCNVCGNRFTTRGNLKVHFHRHR 424
              H+C  C + F S + L  H +  H  ER + C VC   F    +LK H   H+
Sbjct: 1655 RAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQ 1709



 Score = 38.9 bits (89), Expect = 0.025
 Identities = 57/243 (23%), Positives = 81/243 (33%), Gaps = 51/243 (20%)

Query: 775  EDVTDEDSLAGRGSESGGEKAISVRGDSEEASGAEEEVGTVAAAATAGKEMDS----NEK 830
            +D+T   +  G  S SGG   I++  ++   S    +     A +++G   +     +E 
Sbjct: 1472 QDLTQVMTSQGLVSPSGGPHEITLTINNSSLSQVLAQAAGPTATSSSGSPQEITLTISEL 1531

Query: 831  TTQQSSLPPPPPPD-SLDQPQPMEQGSSGVLG------------GKEEGG---------- 867
             T   SLP   P   S    Q +   SSGV G            G   GG          
Sbjct: 1532 NTTSGSLPSTTPMSPSAISTQNLVMSSSGVGGDASVTLTLADTQGMLSGGLDTVTLNITS 1591

Query: 868  ----------KPERSS-----SPASALTPEGEATSVTLVEELSLQEA-------MRKEPG 905
                       P  S      SP   L      ++    EE++ Q A          +P 
Sbjct: 1592 QGQQFPALLTDPSLSGQGGAGSPQVILVSHTPQSASAACEEIAYQVAGVSGNLAPGNQPE 1651

Query: 906  ESSSRKACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAHHQ 965
            +      C  C +AF S A L  H K       +  C  CR+ F     LK+HM    HQ
Sbjct: 1652 KEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHM--QTHQ 1709

Query: 966  VQP 968
              P
Sbjct: 1710 AGP 1712



 Score = 37.7 bits (86), Expect = 0.055
 Identities = 24/78 (30%), Positives = 35/78 (44%), Gaps = 3/78 (3%)

Query: 884 EATSVTLVEELSLQEAMRKEPGESSSRKACEVCGQAFPSQAALEEHQKTHPKEGPLFTCV 943
           E   ++  +E   Q  MR         + C+ C Q F  +  L  H+ TH  E P  TC 
Sbjct: 40  EICLLSFPKESQFQRHMRDHERNDKPHR-CDQCPQTFNVEFNLTLHKCTHSGEDP--TCP 96

Query: 944 FCRQGFLERATLKKHMLL 961
            C + F   A+LK H++L
Sbjct: 97  VCNKKFSRVASLKAHIML 114



 Score = 37.4 bits (85), Expect = 0.072
 Identities = 23/96 (23%), Positives = 44/96 (45%), Gaps = 16/96 (16%)

Query: 889 TLVEELSLQEAMRKEPGESSSRKACEVCGQAFPSQAALEEHQKTHPK------------- 935
           TL  +L++     ++    + + AC+ C + F + + L+EH KTH K             
Sbjct: 131 TLQSQLAVHMEEHRQELAGTRQHACKACKKEFETSSELKEHMKTHYKIRVSSTRSYNRNI 190

Query: 936 --EGPLFTCVFCRQGFLERATLKKHMLLAHHQVQPF 969
              G  ++C  C + F + + L +H+ + H   +PF
Sbjct: 191 DRSGFTYSCPHCGKTFQKPSQLTRHIRI-HTGERPF 225



 Score = 37.4 bits (85), Expect = 0.072
 Identities = 28/85 (32%), Positives = 35/85 (41%), Gaps = 12/85 (14%)

Query: 895 SLQEAMRKEPGESSSRKACEVCGQAFPSQAALEEH-QKTHP--KEGPLFTCVFCRQGFLE 951
           +LQ  M K  GE     AC  C  AF  +  L+ H Q+ H   K GP + C  C   F  
Sbjct: 239 ALQTHMIKHTGEKPH--ACAFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKS 296

Query: 952 RATLKKHMLLAHHQVQPFAPHGPQN 976
             +L  H+   H         GPQN
Sbjct: 297 LGSLNTHISKMH-------MGGPQN 314



 Score = 36.2 bits (82), Expect = 0.16
 Identities = 23/83 (27%), Positives = 35/83 (42%), Gaps = 9/83 (10%)

Query: 886 TSVTLVEELSLQEAMRKEPGESSSRK--------ACEVCGQAFPSQAALEEHQKTHPKEG 937
           TS  L E +     +R     S +R         +C  CG+ F   + L  H + H  E 
Sbjct: 164 TSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIRIHTGER 223

Query: 938 PLFTCVFCRQGFLERATLKKHML 960
           P F C  C + F ++  L+ HM+
Sbjct: 224 P-FKCSECGKAFNQKGALQTHMI 245



 Score = 32.0 bits (71), Expect = 3.0
 Identities = 16/59 (27%), Positives = 23/59 (38%), Gaps = 1/59 (1%)

Query: 913 CEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAHHQVQPFAP 971
           CE+C  +FP ++  + H + H +      C  C Q F     L  H    H    P  P
Sbjct: 39  CEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHK-CTHSGEDPTCP 96



 Score = 30.4 bits (67), Expect = 8.7
 Identities = 18/53 (33%), Positives = 23/53 (43%), Gaps = 1/53 (1%)

Query: 907 SSSRKACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHM 959
           S     C VC + F   A+L+ H   H KE  L  C  C   F  ++ L  HM
Sbjct: 89  SGEDPTCPVCNKKFSRVASLKAHIMLHEKEENLI-CSECGDEFTLQSQLAVHM 140


>gi|69885084 p120E4F [Homo sapiens]
          Length = 784

 Score = 87.4 bits (215), Expect = 6e-17
 Identities = 105/422 (24%), Positives = 169/422 (40%), Gaps = 60/422 (14%)

Query: 327 LLAAQC-LGAARGLEATASPGLLKPKNGSGELSYGEV--MGPLEKPGGRHKCRFCAKVFG 383
           ++AA+  LG     EA  SP     + G G    GE   +  L    GR+ C  C K F 
Sbjct: 147 IVAAEAELGDGEMAEAPGSPR----QQGLGLAGEGEQAQVKLLVNKDGRYVCALCHKTFK 202

Query: 384 SDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPH-------VQMNPHP 436
           + S L+ H+ +H+  + ++C +CG  F T+G+L  H  RH ++ P+              
Sbjct: 203 TGSILKAHMVTHSSRKDHECKLCGASFRTKGSLIRHHRRHTDERPYKCSKCGKSFRESGA 262

Query: 437 VPEHLDYVI-TSSGLPYGMSVPPEKAEEEAATPGGGVERKPLVASTTA-----LSATESL 490
           +  HL  +   +  + + +S     ++E+A   G G     L  +T++     +  +  +
Sbjct: 263 LTRHLKSLTPCTEKIRFSVSKDVVVSKEDARA-GSGAGAAGLGTATSSVTGEPIETSPVI 321

Query: 491 TLLSTSAGTATAPGLPAFNKFVL-MKAVEPKNKADENTPPGSEGSAISGVAESSTATRMQ 549
            L++ + GT          +  L MKA+ P+    +  P  SEGS      E+     MQ
Sbjct: 322 HLVTDAKGTVIHEVHVQMQELSLGMKALAPEPPVSQELPCSSEGS-----RENLLHQAMQ 376

Query: 550 LSKLVTSLPSWAL-LTNHFKSTGSFPFPYVLEPLGASPSETSKLQQLVEKIDRQGAVAVT 608
            S +V    +          + GS P     +PL  +  +   L+  V+ ++ Q    V 
Sbjct: 377 NSGIVLERAAGEEGALEPAPAAGSSP-----QPLAVAAPQLPVLE--VQPLETQ----VA 425

Query: 609 SAASGAPTTSAPAPSSSAS--------------SGPN--QCVICLRVLSCPRALRLHYGQ 652
           S AS  P T  P P  S +              +GP    C  C +       L+ H   
Sbjct: 426 SEASAVPRTH-PCPQCSETFPTAATLEAHKRGHTGPRPFACAQCGKAFPKAYLLKKHQEV 484

Query: 653 HGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARAQNSCPICQKKFTNAVTLQQHVRM 712
           H  ER F+C  CG+ + T     AH  GH+   +      CP C K++      Q H R 
Sbjct: 485 HVRERRFRCGDCGKLYKT----IAHVRGHRRVHSDERPYPCPKCGKRYKTKNAQQVHFRT 540

Query: 713 HL 714
           HL
Sbjct: 541 HL 542



 Score = 57.8 bits (138), Expect = 5e-08
 Identities = 24/59 (40%), Positives = 36/59 (61%)

Query: 372 RHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPHV 430
           R +C  C K++ + + ++ H R H+ ERPY C  CG R+ T+   +VHF  H E+ PHV
Sbjct: 490 RFRCGDCGKLYKTIAHVRGHRRVHSDERPYPCPKCGKRYKTKNAQQVHFRTHLEEKPHV 548



 Score = 57.0 bits (136), Expect = 9e-08
 Identities = 88/396 (22%), Positives = 143/396 (36%), Gaps = 64/396 (16%)

Query: 626 ASSGPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASP 685
           +S   ++C +C        +L  H+ +H  ERP+KC  CG++F   G L  H        
Sbjct: 215 SSRKDHECKLCGASFRTKGSLIRHHRRHTDERPYKCSKCGKSFRESGALTRHL------- 267

Query: 686 AARAQNSCPICQKKF-----TNAVTLQQHVRMHLGGQIPNGGTALPEGGGAAQENGSEQS 740
                 S   C +K       + V  ++  R   G      GTA     G   E      
Sbjct: 268 -----KSLTPCTEKIRFSVSKDVVVSKEDARAGSGAGAAGLGTATSSVTGEPIETSPVIH 322

Query: 741 TVSGA-GSFPQQ---QSQQPS-------PEEELSEEEEEEDEEEEEDVTDEDSLAGRGSE 789
            V+ A G+   +   Q Q+ S       PE  +S+E     E   E++  +   A + S 
Sbjct: 323 LVTDAKGTVIHEVHVQMQELSLGMKALAPEPPVSQELPCSSEGSRENLLHQ---AMQNSG 379

Query: 790 SGGEKAISVRGDSEEASGAEEEVGTVAAAATAGKEMDSNEKTTQQSS--------LPPPP 841
              E+A    G  E A  A      +A AA     ++     TQ +S         P P 
Sbjct: 380 IVLERAAGEEGALEPAPAAGSSPQPLAVAAPQLPVLEVQPLETQVASEASAVPRTHPCPQ 439

Query: 842 PPDSLDQPQPMEQGSSGVLGGKEEGGKPERSSSPASALTPEGEATSV-----------TL 890
             ++      +E    G  G +         + P + L  + +   V            L
Sbjct: 440 CSETFPTAATLEAHKRGHTGPRPFACAQCGKAFPKAYLLKKHQEVHVRERRFRCGDCGKL 499

Query: 891 VEELSLQEAMRKEPGESSSRKACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFL 950
            + ++     R+   +      C  CG+ + ++ A + H +TH +E P   C FC +GF 
Sbjct: 500 YKTIAHVRGHRRVHSDERP-YPCPKCGKRYKTKNAQQVHFRTHLEEKP-HVCQFCSRGFR 557

Query: 951 ERATLKKHMLLAHHQVQP----------FAPHGPQN 976
           E+ +L +H  + HH  +           FA HG  N
Sbjct: 558 EKGSLVRH--VRHHTGEKPFKCYKCGRGFAEHGTLN 591



 Score = 54.3 bits (129), Expect = 6e-07
 Identities = 24/53 (45%), Positives = 31/53 (58%), Gaps = 3/53 (5%)

Query: 367 EKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVH 419
           EKP   H C+FC++ F    +L  H+R HTGE+P+KC  CG  F   G L  H
Sbjct: 544 EKP---HVCQFCSRGFREKGSLVRHVRHHTGEKPFKCYKCGRGFAEHGTLNRH 593



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 18/56 (32%), Positives = 29/56 (51%)

Query: 373 HKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYP 428
           + C  C K + + +A Q+H R+H  E+P+ C  C   F  +G+L  H   H  + P
Sbjct: 519 YPCPKCGKRYKTKNAQQVHFRTHLEEKPHVCQFCSRGFREKGSLVRHVRHHTGEKP 574



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 20/48 (41%), Positives = 24/48 (50%)

Query: 630 PNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAH 677
           P+ C  C R      +L  H   H GE+PFKC  CGR F+  G L  H
Sbjct: 546 PHVCQFCSRGFREKGSLVRHVRHHTGEKPFKCYKCGRGFAEHGTLNRH 593



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 23/82 (28%), Positives = 35/82 (42%), Gaps = 4/82 (4%)

Query: 630 PNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARA 689
           P  C  C +      A ++H+  H  E+P  C+ C R F  +G+L  H   H      + 
Sbjct: 518 PYPCPKCGKRYKTKNAQQVHFRTHLEEKPHVCQFCSRGFREKGSLVRHVRHHTGEKPFK- 576

Query: 690 QNSCPICQKKFTNAVTLQQHVR 711
              C  C + F    TL +H+R
Sbjct: 577 ---CYKCGRGFAEHGTLNRHLR 595



 Score = 40.0 bits (92), Expect = 0.011
 Identities = 17/47 (36%), Positives = 25/47 (53%), Gaps = 1/47 (2%)

Query: 913 CEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHM 959
           C+ C + F  + +L  H + H  E P F C  C +GF E  TL +H+
Sbjct: 549 CQFCSRGFREKGSLVRHVRHHTGEKP-FKCYKCGRGFAEHGTLNRHL 594



 Score = 31.6 bits (70), Expect = 3.9
 Identities = 17/38 (44%), Positives = 21/38 (55%), Gaps = 4/38 (10%)

Query: 28 SEEDHPQV--CAKCCAQFTDPTEFLAH--QNACSTDPP 61
          SEED   V  C +C A+FT   +F+ H  Q AC   PP
Sbjct: 50 SEEDEDDVHRCGRCQAEFTALEDFVQHKIQKACQRAPP 87


>gi|74027276 zinc finger protein 226 isoform a [Homo sapiens]
          Length = 803

 Score = 83.6 bits (205), Expect = 9e-16
 Identities = 86/352 (24%), Positives = 130/352 (36%), Gaps = 19/352 (5%)

Query: 367 EKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREK 426
           EKP   + C  C + F   S LQ H R HTGE+P+KC+ CG  F+   +L+ H      +
Sbjct: 360 EKP---YNCEECGRAFSQASHLQDHQRLHTGEKPFKCDACGKSFSRNSHLQSH------Q 410

Query: 427 YPHVQMNPHPVPEHLDYVITSSGLPYGMSVPPEKAEEEAATPGGGVER-KPLVASTTALS 485
             H    P+   E     I SS L     V   +   +    G G  R   L A     +
Sbjct: 411 RVHTGEKPYKCEECGKGFICSSNLYIHQRVHTGEKPYKCEECGKGFSRPSSLQAHQGVHT 470

Query: 486 ATESLTLLSTSAGTATAPGLPAFNKFVLMKAVEPKNKADENTPPGSEGSAISGVAESSTA 545
             +S        G   +  L A  +    +     N+  ++    S       V      
Sbjct: 471 GEKSYICTVCGKGFTLSSNLQAHQRVHTGEKPYKCNECGKSFRRNSHYQVHLVVHTGEKP 530

Query: 546 TRMQLSKLVTSLPSWALLTNHFKSTGSFPFPYVLEPLGASPSETSKLQ--QLVEKIDRQG 603
            + ++     S  S+  L  H K+  S   P+  E  G   +++S+LQ  QL+   ++  
Sbjct: 531 YKCEICGKGFSQSSY--LQIHQKA-HSIEKPFKCEECGQGFNQSSRLQIHQLIHTGEKPY 587

Query: 604 AVAVTSAASGAPTTSAPAPSSSASSGPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKV 663
                                     P  C  C +V      L  H   H GE+PFKC+ 
Sbjct: 588 KCEECGKGFSRRADLKIHCRIHTGEKPYNCEECGKVFRQASNLLAHQRVHSGEKPFKCEE 647

Query: 664 CGRAFSTRGNLRAHFVGHKASPAARAQNSCPICQKKFTNAVTLQQHVRMHLG 715
           CG++F    +L+AH   H      +    C  C K F  ++ L  H R+H G
Sbjct: 648 CGKSFGRSAHLQAHQKVHTGDKPYK----CDECGKGFKWSLNLDMHQRVHTG 695



 Score = 67.8 bits (164), Expect = 5e-11
 Identities = 31/57 (54%), Positives = 35/57 (61%), Gaps = 3/57 (5%)

Query: 367 EKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRH 423
           EKP   +KC  C KVF   S LQ H R HTGE+PYKC +CG  F+ R NL VH   H
Sbjct: 724 EKP---YKCDVCGKVFSRSSQLQSHQRVHTGEKPYKCEICGKSFSWRSNLTVHHRIH 777



 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 80/350 (22%), Positives = 129/350 (36%), Gaps = 43/350 (12%)

Query: 630 PNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARA 689
           P +C  C +  S P +L+ H G H GE+ + C VCG+ F+   NL+AH   H      + 
Sbjct: 446 PYKCEECGKGFSRPSSLQAHQGVHTGEKSYICTVCGKGFTLSSNLQAHQRVHTGEKPYK- 504

Query: 690 QNSCPICQKKFTNAVTLQQHVRMHLGGQIPNGGTALPEGGGAAQENGSEQSTVSGAGSFP 749
              C  C K F      Q H+ +H  G+ P       +G   +      Q   S    F 
Sbjct: 505 ---CNECGKSFRRNSHYQVHLVVHT-GEKPYKCEICGKGFSQSSYLQIHQKAHSIEKPFK 560

Query: 750 QQQSQQPSPEEELSEEEEEEDEEEEEDVTDEDSLAGRGSESGGEKAISVRGDSEEASGAE 809
            ++  Q   +    +  +     E+    +E    G+G     +  I  R  + E     
Sbjct: 561 CEECGQGFNQSSRLQIHQLIHTGEKPYKCEE---CGKGFSRRADLKIHCRIHTGEKPYNC 617

Query: 810 EEVGTVAAAAT---AGKEMDSNEKTTQ----------QSSLPPPPPPDSLDQPQPMEQGS 856
           EE G V   A+   A + + S EK  +           + L       + D+P   ++  
Sbjct: 618 EECGKVFRQASNLLAHQRVHSGEKPFKCEECGKSFGRSAHLQAHQKVHTGDKPYKCDECG 677

Query: 857 SGVLGGKE--------EGGKPERSSSPASALTPEGEATSVTLVEELSLQEAMRKEPGESS 908
            G               G KP +        +   +A+S+ L + +   E   K      
Sbjct: 678 KGFKWSLNLDMHQRVHTGEKPYKCGECGKYFS---QASSLQLHQSVHTGEKPYK------ 728

Query: 909 SRKACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKH 958
               C+VCG+ F   + L+ HQ+ H  E P + C  C + F  R+ L  H
Sbjct: 729 ----CDVCGKVFSRSSQLQSHQRVHTGEKP-YKCEICGKSFSWRSNLTVH 773



 Score = 64.3 bits (155), Expect = 5e-10
 Identities = 60/233 (25%), Positives = 86/233 (36%), Gaps = 10/233 (4%)

Query: 485 SATESLTLLSTSAGTATAPGLPAFNKFVLMKAVEPKNKADENTPPGSEGSAISGVAESST 544
           S  +SLT +    G   +P LP   K      V  K K DE     S+G+ +    +   
Sbjct: 275 SGEKSLTCVERGKGFCYSPVLPVHQKV----HVGEKLKCDECGKEFSQGAHLQTHQKVHV 330

Query: 545 ATRMQLSKLVTSLPSWALLTNHFKSTGSFPFPYVLEPLGASPSETSKLQQLVEKIDRQGA 604
             +    K      S     N      +   PY  E  G + S+ S LQ        +  
Sbjct: 331 IEKPYKCKQCGKGFSRRSALNVHCKVHTAEKPYNCEECGRAFSQASHLQDHQRLHTGEKP 390

Query: 605 VAVTSAASGAPTTSAPAPSSSASSG--PNQCVICLRVLSCPRALRLHYGQHGGERPFKCK 662
               +        S         +G  P +C  C +   C   L +H   H GE+P+KC+
Sbjct: 391 FKCDACGKSFSRNSHLQSHQRVHTGEKPYKCEECGKGFICSSNLYIHQRVHTGEKPYKCE 450

Query: 663 VCGRAFSTRGNLRAHFVGHKASPAARAQNSCPICQKKFTNAVTLQQHVRMHLG 715
            CG+ FS   +L+AH   H           C +C K FT +  LQ H R+H G
Sbjct: 451 ECGKGFSRPSSLQAHQGVH----TGEKSYICTVCGKGFTLSSNLQAHQRVHTG 499



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 29/64 (45%), Positives = 37/64 (57%), Gaps = 3/64 (4%)

Query: 366 LEKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHRE 425
           +EKP    KC  C + F   S LQIH   HTGE+PYKC  CG  F+ R +LK+H   H  
Sbjct: 555 IEKP---FKCEECGQGFNQSSRLQIHQLIHTGEKPYKCEECGKGFSRRADLKIHCRIHTG 611

Query: 426 KYPH 429
           + P+
Sbjct: 612 EKPY 615



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 35/113 (30%), Positives = 54/113 (47%), Gaps = 8/113 (7%)

Query: 630 PNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARA 689
           P +C  C +  S   +L+LH   H GE+P+KC VCG+ FS    L++H   H      + 
Sbjct: 698 PYKCGECGKYFSQASSLQLHQSVHTGEKPYKCDVCGKVFSRSSQLQSHQRVHTGEKPYK- 756

Query: 690 QNSCPICQKKFTNAVTLQQHVRMHLGGQIPNGGTALPEGGGAAQENGSEQSTV 742
              C IC K F+    L  H R+H+G +          GG   +E+  E+ ++
Sbjct: 757 ---CEICGKSFSWRSNLTVHHRIHVGDKSYKSN----RGGKNIRESTQEKKSI 802



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 28/63 (44%), Positives = 37/63 (58%), Gaps = 3/63 (4%)

Query: 367 EKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREK 426
           EKP   +KC  C K F   S+LQ+H   HTGE+PYKC+VCG  F+    L+ H   H  +
Sbjct: 696 EKP---YKCGECGKYFSQASSLQLHQSVHTGEKPYKCDVCGKVFSRSSQLQSHQRVHTGE 752

Query: 427 YPH 429
            P+
Sbjct: 753 KPY 755



 Score = 57.4 bits (137), Expect = 7e-08
 Identities = 30/77 (38%), Positives = 38/77 (49%), Gaps = 3/77 (3%)

Query: 352 NGSGELSYGEVMGPLEKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFT 411
           N S  L   +++   EKP   +KC  C K F   + L+IH R HTGE+PY C  CG  F 
Sbjct: 569 NQSSRLQIHQLIHTGEKP---YKCEECGKGFSRRADLKIHCRIHTGEKPYNCEECGKVFR 625

Query: 412 TRGNLKVHFHRHREKYP 428
              NL  H   H  + P
Sbjct: 626 QASNLLAHQRVHSGEKP 642



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 27/63 (42%), Positives = 35/63 (55%), Gaps = 3/63 (4%)

Query: 367 EKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREK 426
           EKP    KC  C K FG  + LQ H + HTG++PYKC+ CG  F    NL +H   H  +
Sbjct: 640 EKP---FKCEECGKSFGRSAHLQAHQKVHTGDKPYKCDECGKGFKWSLNLDMHQRVHTGE 696

Query: 427 YPH 429
            P+
Sbjct: 697 KPY 699



 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 25/63 (39%), Positives = 35/63 (55%), Gaps = 3/63 (4%)

Query: 366 LEKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHRE 425
           +EKP   +KC+ C K F   SAL +H + HT E+PY C  CG  F+   +L+ H   H  
Sbjct: 331 IEKP---YKCKQCGKGFSRRSALNVHCKVHTAEKPYNCEECGRAFSQASHLQDHQRLHTG 387

Query: 426 KYP 428
           + P
Sbjct: 388 EKP 390



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 24/60 (40%), Positives = 31/60 (51%)

Query: 370 GGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPH 429
           G + KC  C K F   + LQ H + H  E+PYKC  CG  F+ R  L VH   H  + P+
Sbjct: 304 GEKLKCDECGKEFSQGAHLQTHQKVHVIEKPYKCKQCGKGFSRRSALNVHCKVHTAEKPY 363



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 23/57 (40%), Positives = 32/57 (56%)

Query: 373 HKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPH 429
           +KC  C K F     L +H R HTGE+PYKC  CG  F+   +L++H   H  + P+
Sbjct: 671 YKCDECGKGFKWSLNLDMHQRVHTGEKPYKCGECGKYFSQASSLQLHQSVHTGEKPY 727



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 23/57 (40%), Positives = 33/57 (57%), Gaps = 2/57 (3%)

Query: 913 CEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAHHQVQPF 969
           CE+CG+ F   + L+ HQK H  E P F C  C QGF + + L+ H L+ H   +P+
Sbjct: 533 CEICGKGFSQSSYLQIHQKAHSIEKP-FKCEECGQGFNQSSRLQIHQLI-HTGEKPY 587



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 21/63 (33%), Positives = 33/63 (52%), Gaps = 3/63 (4%)

Query: 896 LQEAMRKEPGESSSRKACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATL 955
           LQ+  R   GE   +  C+ CG++F   + L+ HQ+ H  E P + C  C +GF+  + L
Sbjct: 378 LQDHQRLHTGEKPFK--CDACGKSFSRNSHLQSHQRVHTGEKP-YKCEECGKGFICSSNL 434

Query: 956 KKH 958
             H
Sbjct: 435 YIH 437



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 19/46 (41%), Positives = 25/46 (54%), Gaps = 1/46 (2%)

Query: 913 CEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKH 958
           C+ CG+ F   A L+ HQK H  E P + C  C +GF  R+ L  H
Sbjct: 309 CDECGKEFSQGAHLQTHQKVHVIEKP-YKCKQCGKGFSRRSALNVH 353



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 18/46 (39%), Positives = 26/46 (56%), Gaps = 1/46 (2%)

Query: 913 CEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKH 958
           CE CG+AF   + L++HQ+ H  E P F C  C + F   + L+ H
Sbjct: 365 CEECGRAFSQASHLQDHQRLHTGEKP-FKCDACGKSFSRNSHLQSH 409



 Score = 38.5 bits (88), Expect = 0.032
 Identities = 22/63 (34%), Positives = 31/63 (49%), Gaps = 3/63 (4%)

Query: 896 LQEAMRKEPGESSSRKACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATL 955
           LQ   R   GE   +  CE CG+ F   + L  HQ+ H  E P + C  C +GF   ++L
Sbjct: 406 LQSHQRVHTGEKPYK--CEECGKGFICSSNLYIHQRVHTGEKP-YKCEECGKGFSRPSSL 462

Query: 956 KKH 958
           + H
Sbjct: 463 QAH 465



 Score = 38.1 bits (87), Expect = 0.042
 Identities = 20/57 (35%), Positives = 30/57 (52%), Gaps = 2/57 (3%)

Query: 913 CEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAHHQVQPF 969
           C+ CG+ F  ++AL  H K H  E P + C  C + F + + L+ H  L H   +PF
Sbjct: 337 CKQCGKGFSRRSALNVHCKVHTAEKP-YNCEECGRAFSQASHLQDHQRL-HTGEKPF 391



 Score = 37.4 bits (85), Expect = 0.072
 Identities = 24/75 (32%), Positives = 35/75 (46%), Gaps = 4/75 (5%)

Query: 895 SLQEAMRKEPGESSSRKACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERAT 954
           SLQ       GE S    C VCG+ F   + L+ HQ+ H  E P + C  C + F   + 
Sbjct: 461 SLQAHQGVHTGEKSY--ICTVCGKGFTLSSNLQAHQRVHTGEKP-YKCNECGKSFRRNSH 517

Query: 955 LKKHMLLAHHQVQPF 969
            + H L+ H   +P+
Sbjct: 518 YQVH-LVVHTGEKPY 531



 Score = 36.2 bits (82), Expect = 0.16
 Identities = 17/38 (44%), Positives = 21/38 (55%), Gaps = 3/38 (7%)

Query: 367 EKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCN 404
           EKP   +KC  C K F   S L +H R H G++ YK N
Sbjct: 752 EKP---YKCEICGKSFSWRSNLTVHHRIHVGDKSYKSN 786



 Score = 34.3 bits (77), Expect = 0.61
 Identities = 19/57 (33%), Positives = 29/57 (50%), Gaps = 2/57 (3%)

Query: 913 CEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAHHQVQPF 969
           CE CG+ F  +A L+ H + H  E P + C  C + F + + L  H  + H   +PF
Sbjct: 589 CEECGKGFSRRADLKIHCRIHTGEKP-YNCEECGKVFRQASNLLAHQRV-HSGEKPF 643



 Score = 33.5 bits (75), Expect = 1.0
 Identities = 22/83 (26%), Positives = 32/83 (38%), Gaps = 5/83 (6%)

Query: 632 QCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARAQN 691
           QC  C +  S   +  LH     GE+   C   G+ F     L  H   H        + 
Sbjct: 253 QCNECKKPFSDLSSFDLHQQLQSGEKSLTCVERGKGFCYSPVLPVHQKVHVGE-----KL 307

Query: 692 SCPICQKKFTNAVTLQQHVRMHL 714
            C  C K+F+    LQ H ++H+
Sbjct: 308 KCDECGKEFSQGAHLQTHQKVHV 330


>gi|74027274 zinc finger protein 226 isoform a [Homo sapiens]
          Length = 803

 Score = 83.6 bits (205), Expect = 9e-16
 Identities = 86/352 (24%), Positives = 130/352 (36%), Gaps = 19/352 (5%)

Query: 367 EKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREK 426
           EKP   + C  C + F   S LQ H R HTGE+P+KC+ CG  F+   +L+ H      +
Sbjct: 360 EKP---YNCEECGRAFSQASHLQDHQRLHTGEKPFKCDACGKSFSRNSHLQSH------Q 410

Query: 427 YPHVQMNPHPVPEHLDYVITSSGLPYGMSVPPEKAEEEAATPGGGVER-KPLVASTTALS 485
             H    P+   E     I SS L     V   +   +    G G  R   L A     +
Sbjct: 411 RVHTGEKPYKCEECGKGFICSSNLYIHQRVHTGEKPYKCEECGKGFSRPSSLQAHQGVHT 470

Query: 486 ATESLTLLSTSAGTATAPGLPAFNKFVLMKAVEPKNKADENTPPGSEGSAISGVAESSTA 545
             +S        G   +  L A  +    +     N+  ++    S       V      
Sbjct: 471 GEKSYICTVCGKGFTLSSNLQAHQRVHTGEKPYKCNECGKSFRRNSHYQVHLVVHTGEKP 530

Query: 546 TRMQLSKLVTSLPSWALLTNHFKSTGSFPFPYVLEPLGASPSETSKLQ--QLVEKIDRQG 603
            + ++     S  S+  L  H K+  S   P+  E  G   +++S+LQ  QL+   ++  
Sbjct: 531 YKCEICGKGFSQSSY--LQIHQKA-HSIEKPFKCEECGQGFNQSSRLQIHQLIHTGEKPY 587

Query: 604 AVAVTSAASGAPTTSAPAPSSSASSGPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKV 663
                                     P  C  C +V      L  H   H GE+PFKC+ 
Sbjct: 588 KCEECGKGFSRRADLKIHCRIHTGEKPYNCEECGKVFRQASNLLAHQRVHSGEKPFKCEE 647

Query: 664 CGRAFSTRGNLRAHFVGHKASPAARAQNSCPICQKKFTNAVTLQQHVRMHLG 715
           CG++F    +L+AH   H      +    C  C K F  ++ L  H R+H G
Sbjct: 648 CGKSFGRSAHLQAHQKVHTGDKPYK----CDECGKGFKWSLNLDMHQRVHTG 695



 Score = 67.8 bits (164), Expect = 5e-11
 Identities = 31/57 (54%), Positives = 35/57 (61%), Gaps = 3/57 (5%)

Query: 367 EKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRH 423
           EKP   +KC  C KVF   S LQ H R HTGE+PYKC +CG  F+ R NL VH   H
Sbjct: 724 EKP---YKCDVCGKVFSRSSQLQSHQRVHTGEKPYKCEICGKSFSWRSNLTVHHRIH 777



 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 80/350 (22%), Positives = 129/350 (36%), Gaps = 43/350 (12%)

Query: 630 PNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARA 689
           P +C  C +  S P +L+ H G H GE+ + C VCG+ F+   NL+AH   H      + 
Sbjct: 446 PYKCEECGKGFSRPSSLQAHQGVHTGEKSYICTVCGKGFTLSSNLQAHQRVHTGEKPYK- 504

Query: 690 QNSCPICQKKFTNAVTLQQHVRMHLGGQIPNGGTALPEGGGAAQENGSEQSTVSGAGSFP 749
              C  C K F      Q H+ +H  G+ P       +G   +      Q   S    F 
Sbjct: 505 ---CNECGKSFRRNSHYQVHLVVHT-GEKPYKCEICGKGFSQSSYLQIHQKAHSIEKPFK 560

Query: 750 QQQSQQPSPEEELSEEEEEEDEEEEEDVTDEDSLAGRGSESGGEKAISVRGDSEEASGAE 809
            ++  Q   +    +  +     E+    +E    G+G     +  I  R  + E     
Sbjct: 561 CEECGQGFNQSSRLQIHQLIHTGEKPYKCEE---CGKGFSRRADLKIHCRIHTGEKPYNC 617

Query: 810 EEVGTVAAAAT---AGKEMDSNEKTTQ----------QSSLPPPPPPDSLDQPQPMEQGS 856
           EE G V   A+   A + + S EK  +           + L       + D+P   ++  
Sbjct: 618 EECGKVFRQASNLLAHQRVHSGEKPFKCEECGKSFGRSAHLQAHQKVHTGDKPYKCDECG 677

Query: 857 SGVLGGKE--------EGGKPERSSSPASALTPEGEATSVTLVEELSLQEAMRKEPGESS 908
            G               G KP +        +   +A+S+ L + +   E   K      
Sbjct: 678 KGFKWSLNLDMHQRVHTGEKPYKCGECGKYFS---QASSLQLHQSVHTGEKPYK------ 728

Query: 909 SRKACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKH 958
               C+VCG+ F   + L+ HQ+ H  E P + C  C + F  R+ L  H
Sbjct: 729 ----CDVCGKVFSRSSQLQSHQRVHTGEKP-YKCEICGKSFSWRSNLTVH 773



 Score = 64.3 bits (155), Expect = 5e-10
 Identities = 60/233 (25%), Positives = 86/233 (36%), Gaps = 10/233 (4%)

Query: 485 SATESLTLLSTSAGTATAPGLPAFNKFVLMKAVEPKNKADENTPPGSEGSAISGVAESST 544
           S  +SLT +    G   +P LP   K      V  K K DE     S+G+ +    +   
Sbjct: 275 SGEKSLTCVERGKGFCYSPVLPVHQKV----HVGEKLKCDECGKEFSQGAHLQTHQKVHV 330

Query: 545 ATRMQLSKLVTSLPSWALLTNHFKSTGSFPFPYVLEPLGASPSETSKLQQLVEKIDRQGA 604
             +    K      S     N      +   PY  E  G + S+ S LQ        +  
Sbjct: 331 IEKPYKCKQCGKGFSRRSALNVHCKVHTAEKPYNCEECGRAFSQASHLQDHQRLHTGEKP 390

Query: 605 VAVTSAASGAPTTSAPAPSSSASSG--PNQCVICLRVLSCPRALRLHYGQHGGERPFKCK 662
               +        S         +G  P +C  C +   C   L +H   H GE+P+KC+
Sbjct: 391 FKCDACGKSFSRNSHLQSHQRVHTGEKPYKCEECGKGFICSSNLYIHQRVHTGEKPYKCE 450

Query: 663 VCGRAFSTRGNLRAHFVGHKASPAARAQNSCPICQKKFTNAVTLQQHVRMHLG 715
            CG+ FS   +L+AH   H           C +C K FT +  LQ H R+H G
Sbjct: 451 ECGKGFSRPSSLQAHQGVH----TGEKSYICTVCGKGFTLSSNLQAHQRVHTG 499



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 29/64 (45%), Positives = 37/64 (57%), Gaps = 3/64 (4%)

Query: 366 LEKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHRE 425
           +EKP    KC  C + F   S LQIH   HTGE+PYKC  CG  F+ R +LK+H   H  
Sbjct: 555 IEKP---FKCEECGQGFNQSSRLQIHQLIHTGEKPYKCEECGKGFSRRADLKIHCRIHTG 611

Query: 426 KYPH 429
           + P+
Sbjct: 612 EKPY 615



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 35/113 (30%), Positives = 54/113 (47%), Gaps = 8/113 (7%)

Query: 630 PNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARA 689
           P +C  C +  S   +L+LH   H GE+P+KC VCG+ FS    L++H   H      + 
Sbjct: 698 PYKCGECGKYFSQASSLQLHQSVHTGEKPYKCDVCGKVFSRSSQLQSHQRVHTGEKPYK- 756

Query: 690 QNSCPICQKKFTNAVTLQQHVRMHLGGQIPNGGTALPEGGGAAQENGSEQSTV 742
              C IC K F+    L  H R+H+G +          GG   +E+  E+ ++
Sbjct: 757 ---CEICGKSFSWRSNLTVHHRIHVGDKSYKSN----RGGKNIRESTQEKKSI 802



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 28/63 (44%), Positives = 37/63 (58%), Gaps = 3/63 (4%)

Query: 367 EKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREK 426
           EKP   +KC  C K F   S+LQ+H   HTGE+PYKC+VCG  F+    L+ H   H  +
Sbjct: 696 EKP---YKCGECGKYFSQASSLQLHQSVHTGEKPYKCDVCGKVFSRSSQLQSHQRVHTGE 752

Query: 427 YPH 429
            P+
Sbjct: 753 KPY 755



 Score = 57.4 bits (137), Expect = 7e-08
 Identities = 30/77 (38%), Positives = 38/77 (49%), Gaps = 3/77 (3%)

Query: 352 NGSGELSYGEVMGPLEKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFT 411
           N S  L   +++   EKP   +KC  C K F   + L+IH R HTGE+PY C  CG  F 
Sbjct: 569 NQSSRLQIHQLIHTGEKP---YKCEECGKGFSRRADLKIHCRIHTGEKPYNCEECGKVFR 625

Query: 412 TRGNLKVHFHRHREKYP 428
              NL  H   H  + P
Sbjct: 626 QASNLLAHQRVHSGEKP 642



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 27/63 (42%), Positives = 35/63 (55%), Gaps = 3/63 (4%)

Query: 367 EKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREK 426
           EKP    KC  C K FG  + LQ H + HTG++PYKC+ CG  F    NL +H   H  +
Sbjct: 640 EKP---FKCEECGKSFGRSAHLQAHQKVHTGDKPYKCDECGKGFKWSLNLDMHQRVHTGE 696

Query: 427 YPH 429
            P+
Sbjct: 697 KPY 699



 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 25/63 (39%), Positives = 35/63 (55%), Gaps = 3/63 (4%)

Query: 366 LEKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHRE 425
           +EKP   +KC+ C K F   SAL +H + HT E+PY C  CG  F+   +L+ H   H  
Sbjct: 331 IEKP---YKCKQCGKGFSRRSALNVHCKVHTAEKPYNCEECGRAFSQASHLQDHQRLHTG 387

Query: 426 KYP 428
           + P
Sbjct: 388 EKP 390



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 24/60 (40%), Positives = 31/60 (51%)

Query: 370 GGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPH 429
           G + KC  C K F   + LQ H + H  E+PYKC  CG  F+ R  L VH   H  + P+
Sbjct: 304 GEKLKCDECGKEFSQGAHLQTHQKVHVIEKPYKCKQCGKGFSRRSALNVHCKVHTAEKPY 363



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 23/57 (40%), Positives = 32/57 (56%)

Query: 373 HKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPH 429
           +KC  C K F     L +H R HTGE+PYKC  CG  F+   +L++H   H  + P+
Sbjct: 671 YKCDECGKGFKWSLNLDMHQRVHTGEKPYKCGECGKYFSQASSLQLHQSVHTGEKPY 727



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 23/57 (40%), Positives = 33/57 (57%), Gaps = 2/57 (3%)

Query: 913 CEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAHHQVQPF 969
           CE+CG+ F   + L+ HQK H  E P F C  C QGF + + L+ H L+ H   +P+
Sbjct: 533 CEICGKGFSQSSYLQIHQKAHSIEKP-FKCEECGQGFNQSSRLQIHQLI-HTGEKPY 587



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 21/63 (33%), Positives = 33/63 (52%), Gaps = 3/63 (4%)

Query: 896 LQEAMRKEPGESSSRKACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATL 955
           LQ+  R   GE   +  C+ CG++F   + L+ HQ+ H  E P + C  C +GF+  + L
Sbjct: 378 LQDHQRLHTGEKPFK--CDACGKSFSRNSHLQSHQRVHTGEKP-YKCEECGKGFICSSNL 434

Query: 956 KKH 958
             H
Sbjct: 435 YIH 437



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 19/46 (41%), Positives = 25/46 (54%), Gaps = 1/46 (2%)

Query: 913 CEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKH 958
           C+ CG+ F   A L+ HQK H  E P + C  C +GF  R+ L  H
Sbjct: 309 CDECGKEFSQGAHLQTHQKVHVIEKP-YKCKQCGKGFSRRSALNVH 353



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 18/46 (39%), Positives = 26/46 (56%), Gaps = 1/46 (2%)

Query: 913 CEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKH 958
           CE CG+AF   + L++HQ+ H  E P F C  C + F   + L+ H
Sbjct: 365 CEECGRAFSQASHLQDHQRLHTGEKP-FKCDACGKSFSRNSHLQSH 409



 Score = 38.5 bits (88), Expect = 0.032
 Identities = 22/63 (34%), Positives = 31/63 (49%), Gaps = 3/63 (4%)

Query: 896 LQEAMRKEPGESSSRKACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATL 955
           LQ   R   GE   +  CE CG+ F   + L  HQ+ H  E P + C  C +GF   ++L
Sbjct: 406 LQSHQRVHTGEKPYK--CEECGKGFICSSNLYIHQRVHTGEKP-YKCEECGKGFSRPSSL 462

Query: 956 KKH 958
           + H
Sbjct: 463 QAH 465



 Score = 38.1 bits (87), Expect = 0.042
 Identities = 20/57 (35%), Positives = 30/57 (52%), Gaps = 2/57 (3%)

Query: 913 CEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAHHQVQPF 969
           C+ CG+ F  ++AL  H K H  E P + C  C + F + + L+ H  L H   +PF
Sbjct: 337 CKQCGKGFSRRSALNVHCKVHTAEKP-YNCEECGRAFSQASHLQDHQRL-HTGEKPF 391



 Score = 37.4 bits (85), Expect = 0.072
 Identities = 24/75 (32%), Positives = 35/75 (46%), Gaps = 4/75 (5%)

Query: 895 SLQEAMRKEPGESSSRKACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERAT 954
           SLQ       GE S    C VCG+ F   + L+ HQ+ H  E P + C  C + F   + 
Sbjct: 461 SLQAHQGVHTGEKSY--ICTVCGKGFTLSSNLQAHQRVHTGEKP-YKCNECGKSFRRNSH 517

Query: 955 LKKHMLLAHHQVQPF 969
            + H L+ H   +P+
Sbjct: 518 YQVH-LVVHTGEKPY 531



 Score = 36.2 bits (82), Expect = 0.16
 Identities = 17/38 (44%), Positives = 21/38 (55%), Gaps = 3/38 (7%)

Query: 367 EKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCN 404
           EKP   +KC  C K F   S L +H R H G++ YK N
Sbjct: 752 EKP---YKCEICGKSFSWRSNLTVHHRIHVGDKSYKSN 786



 Score = 34.3 bits (77), Expect = 0.61
 Identities = 19/57 (33%), Positives = 29/57 (50%), Gaps = 2/57 (3%)

Query: 913 CEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAHHQVQPF 969
           CE CG+ F  +A L+ H + H  E P + C  C + F + + L  H  + H   +PF
Sbjct: 589 CEECGKGFSRRADLKIHCRIHTGEKP-YNCEECGKVFRQASNLLAHQRV-HSGEKPF 643



 Score = 33.5 bits (75), Expect = 1.0
 Identities = 22/83 (26%), Positives = 32/83 (38%), Gaps = 5/83 (6%)

Query: 632 QCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARAQN 691
           QC  C +  S   +  LH     GE+   C   G+ F     L  H   H        + 
Sbjct: 253 QCNECKKPFSDLSSFDLHQQLQSGEKSLTCVERGKGFCYSPVLPVHQKVHVGE-----KL 307

Query: 692 SCPICQKKFTNAVTLQQHVRMHL 714
            C  C K+F+    LQ H ++H+
Sbjct: 308 KCDECGKEFSQGAHLQTHQKVHV 330


>gi|239757409 PREDICTED: similar to zinc finger protein 208 [Homo
           sapiens]
          Length = 1059

 Score = 81.3 bits (199), Expect = 4e-15
 Identities = 149/636 (23%), Positives = 221/636 (34%), Gaps = 83/636 (13%)

Query: 113 GPERRGEESPGHFLVAATGTAAGGGGGLILASPKLGATPLPP----ESTPAPPPPPPPPP 168
           GP + G   P   L A   +AA       ++S    ATP+ P    + + AP     PPP
Sbjct: 283 GPPQPGPHLPPLGLPAPAASAATAAAPSTVSSGP-PATPVAPAPSADGSAAPAGVGVPPP 341

Query: 169 PPGVGSGHLNIPLILEELRVLQQRQIHQMQMTEQICRQVLLLGSLGQTVGAPASPSELPG 228
             G G G    PL  +  +       HQ+  T +   +        ++     S      
Sbjct: 342 ATGGGDGPFACPLCWKVFKKPSHLHQHQIIHTGE---KPFSCSVCSKSFNRRESLKRHVK 398

Query: 229 TGTASSTKPLLPLFSPIKPVQTSKTLASSSSSSSSSSGAETPKQAF-------------F 275
           T +A   +  LP     K  + +  L    ++ + + GA  P+  +              
Sbjct: 399 THSADLLR--LPCGICGKAFRDASYLLKHQAAHAGA-GAGGPRPVYPCDLCGKSYSAPQS 455

Query: 276 HLYHPLGSQHPFSAGGVGRSHKPT-PAPSPALPGSTDQLIASPHLAFPSTTGLLAAQCL- 333
            L H      P +A    +    + P P P  P     L   P           AA  + 
Sbjct: 456 LLRHKAAHAPPAAAAEAPKDGAASAPQPPPTFPPGPYLLPPDPPTTDSEKAAAAAAAVVY 515

Query: 334 GAARGLEATASPGLLKPKNGSGELSYGEVMGPLEKPGGRHKCRFCAKVFGSDSALQIHLR 393
           GA       A P LL     SG    G  +     PG    C  C + FG    L+ H R
Sbjct: 516 GAVPVPLLGAHPLLLGGAGTSGAGGSGASV-----PGKTFCCGICGRGFGRRETLKRHER 570

Query: 394 SHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPH-------VQMNPHPVPEH--LDYV 444
            HTGE+P++C VCG RF    +L  H   H  + P+       V   P  +  H  +  +
Sbjct: 571 IHTGEKPHQCPVCGKRFRESFHLSKHHVVHTRERPYKCELCGKVFGYPQSLTRHRQVHRL 630

Query: 445 ITSSGLPYGMSVPPEKAEEEAATPGGGVERKPLVASTTALSATESLTLLSTSAGTATAPG 504
                L     +P  +    A  PG         AS T+   T+ L+   +  G      
Sbjct: 631 QLPCALAGAAGLPSTQGTPGACGPG---------ASGTSAGPTDGLSYACSDCG----EH 677

Query: 505 LPAFNKFVLMKAVEPKNKADENTPPGSEGSAIS-GVAESSTATRMQLSKLVTSLPSWALL 563
            P     +  K V    K     P G +    + G  E+     +   KLV       LL
Sbjct: 678 FPDLFHVMSHKEVHMAEK-----PYGCDACGKTFGFIEN-----LMWHKLVHQAAPERLL 727

Query: 564 TNHFKSTGSFPFPYVLEPL-GASPSETSKLQQLVEKIDRQGAVAVTSAASGAPTTSAPAP 622
                     P P  L+P  G+S ++ + +       +   AVA  +  SG       A 
Sbjct: 728 P---------PAPGGLQPPDGSSGTDAASVLDNGLAGEVGAAVAALAGVSGGEDAGGAAV 778

Query: 623 SSS---ASSGPNQ--CVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAH 677
           + +   ASSGP +  C  C +       L  H   H   R   C +CG++F+   +L  H
Sbjct: 779 AGAGGGASSGPERFSCATCGQSFKHFLGLVTHKYVHLVRRTLGCGLCGQSFAGAYDLLLH 838

Query: 678 FVGHKASPAARAQNSCPICQKKFTNAVTLQQHVRMH 713
              H+     R    CP+C K+F  A  L +H R H
Sbjct: 839 RRSHRQKRGFR----CPVCGKRFWEAALLMRHQRCH 870



 Score = 70.5 bits (171), Expect = 8e-12
 Identities = 44/129 (34%), Positives = 60/129 (46%), Gaps = 20/129 (15%)

Query: 604 AVAVTSAASGAPTTS-APAPSSSASS----------------GPNQCVICLRVLSCPRAL 646
           A A ++ +SG P T  APAPS+  S+                GP  C +C +V   P  L
Sbjct: 306 AAAPSTVSSGPPATPVAPAPSADGSAAPAGVGVPPPATGGGDGPFACPLCWKVFKKPSHL 365

Query: 647 RLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARAQNSCPICQKKFTNAVTL 706
             H   H GE+PF C VC ++F+ R +L+ H   H A      +  C IC K F +A  L
Sbjct: 366 HQHQIIHTGEKPFSCSVCSKSFNRRESLKRHVKTHSAD---LLRLPCGICGKAFRDASYL 422

Query: 707 QQHVRMHLG 715
            +H   H G
Sbjct: 423 LKHQAAHAG 431



 Score = 64.7 bits (156), Expect = 4e-10
 Identities = 110/432 (25%), Positives = 154/432 (35%), Gaps = 80/432 (18%)

Query: 574 PFPYVLEPLGASPSETSKLQQLVEKIDRQGAVAVTSAAS------GAPTTSAPAPSSSAS 627
           P PY+L P    P+  S+           GAV V    +      GA T+ A    +S  
Sbjct: 489 PGPYLLPP--DPPTTDSEKAAAAAAAVVYGAVPVPLLGAHPLLLGGAGTSGAGGSGASVP 546

Query: 628 SGPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAA 687
                C IC R       L+ H   H GE+P +C VCG+ F    +L  H V H      
Sbjct: 547 GKTFCCGICGRGFGRRETLKRHERIHTGEKPHQCPVCGKRFRESFHLSKHHVVHTRERPY 606

Query: 688 RAQNSCPICQKKFTNAVTLQQHVRMHLGGQIP---NGGTALPEGGGAAQENGSEQSTVSG 744
           +    C +C K F    +L +H ++H   Q+P    G   LP          S Q T   
Sbjct: 607 K----CELCGKVFGYPQSLTRHRQVHRL-QLPCALAGAAGLP----------STQGTPGA 651

Query: 745 AGSFPQQQSQQPSPEEELSEEEEEEDEEEEEDVTDEDSLAGRGSESGGEKAISVRGDS-E 803
            G      S  P+                       D L+   S+ G          S +
Sbjct: 652 CGPGASGTSAGPT-----------------------DGLSYACSDCGEHFPDLFHVMSHK 688

Query: 804 EASGAEEEVGTVAAAATAGK-EMDSNEKTTQQSS----LPPPP----PPDS--------- 845
           E   AE+  G  A   T G  E     K   Q++    LPP P    PPD          
Sbjct: 689 EVHMAEKPYGCDACGKTFGFIENLMWHKLVHQAAPERLLPPAPGGLQPPDGSSGTDAASV 748

Query: 846 LDQPQPMEQGSS-----GVLGGKEEGGKPERSSSPASALTPEGEATSVTLVEELS--LQE 898
           LD     E G++     GV GG++ GG     +   ++  PE   +  T  +     L  
Sbjct: 749 LDNGLAGEVGAAVAALAGVSGGEDAGGAAVAGAGGGASSGPE-RFSCATCGQSFKHFLGL 807

Query: 899 AMRKEPGESSSRKACEVCGQAFPSQAALEEHQKTH-PKEGPLFTCVFCRQGFLERATLKK 957
              K          C +CGQ+F     L  H+++H  K G  F C  C + F E A L +
Sbjct: 808 VTHKYVHLVRRTLGCGLCGQSFAGAYDLLLHRRSHRQKRG--FRCPVCGKRFWEAALLMR 865

Query: 958 HMLLAHHQVQPF 969
           H    H + +P+
Sbjct: 866 HQ-RCHTEQRPY 876



 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 70/274 (25%), Positives = 97/274 (35%), Gaps = 63/274 (22%)

Query: 242 FSPIKPVQTSKTLASSSSSSSSSSGAETPKQAFFHLYHPLGSQHPFSAGGVGRSHKPTPA 301
           F P   V +S + +SSSSSSSSSS +                    S+    ++ KP P 
Sbjct: 85  FKPKAEVPSSSSSSSSSSSSSSSSSSS-------------------SSSSSSQAKKPDPP 125

Query: 302 PSPAL----PGSTDQLIASPHLAFPSTTGLLAAQCLGAARGLEATASPGLLKPKNGSGEL 357
             PA     P   D    +P       +G       G  +     + PG+  P  G+   
Sbjct: 126 LPPAFGAPPPPLFDAAFPTPQWGIVDLSG--HQHLFGNLKRGGPASGPGVT-PGLGAPAG 182

Query: 358 SYGEVMGPLEKPGG--------------------------RHKCRFCAKVFGSDSALQIH 391
           + G +  P + P G                          R  C  C K F   S L  H
Sbjct: 183 APGPLPAPSQTPPGPPAAAACDPTKDDKGYFRRLKYLMERRFPCGVCQKSFKQSSHLVQH 242

Query: 392 LRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPHVQMNPHPVPEHLDYVITSSGLP 451
           +  H+GERPY+C VCG  +    +L  H   H++  P     P P P HL         P
Sbjct: 243 MLVHSGERPYECGVCGRTYNHVSSLIRHRRCHKDVPPAAGGPPQPGP-HLP--------P 293

Query: 452 YGMSVPPEKAEEEAA--TPGGGVERKPLVASTTA 483
            G+  P   A   AA  T   G    P+  + +A
Sbjct: 294 LGLPAPAASAATAAAPSTVSSGPPATPVAPAPSA 327



 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 92/407 (22%), Positives = 145/407 (35%), Gaps = 49/407 (12%)

Query: 333  LGAARGLEAT-ASPGLLKPKNGSGELSYGEVMGPLEKPGGRHKCRFCAKVFGSDSALQIH 391
            L  A GL +T  +PG   P       + G   GP +  G  + C  C + F     +  H
Sbjct: 636  LAGAAGLPSTQGTPGACGPG------ASGTSAGPTD--GLSYACSDCGEHFPDLFHVMSH 687

Query: 392  LRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPHVQMNPHPVPEHLDYVITSSGLP 451
               H  E+PY C+ CG  F    NL  H   H+             PE L         P
Sbjct: 688  KEVHMAEKPYGCDACGKTFGFIENLMWHKLVHQA-----------APERL-----LPPAP 731

Query: 452  YGMSVPPEKAEEEAATP---GGGVERKPLVASTTALSATESL---TLLSTSAGTATAPGL 505
             G+  P   +  +AA+    G   E    VA+   +S  E      +     G ++ P  
Sbjct: 732  GGLQPPDGSSGTDAASVLDNGLAGEVGAAVAALAGVSGGEDAGGAAVAGAGGGASSGPER 791

Query: 506  -------PAFNKFVLMKAVEPKNKADENTPPGSEGSAISGVAESSTATRMQLSKLVTSLP 558
                    +F  F+ +   +  +        G  G + +G  +     R    K     P
Sbjct: 792  FSCATCGQSFKHFLGLVTHKYVHLVRRTLGCGLCGQSFAGAYDLLLHRRSHRQKRGFRCP 851

Query: 559  S-----W--ALLTNHFKS-TGSFPFPYVLEPLGASPSETSKLQQLVEKIDRQGAVAVTSA 610
                  W  ALL  H +  T   P+   +   G   S   +  ++V   +R     V + 
Sbjct: 852  VCGKRFWEAALLMRHQRCHTEQRPYRCGVCGRGFLRSWYLRQHRVVHTGERAFKCGVCAK 911

Query: 611  ASGAPTTSAPAPSSSASSGPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFST 670
                 ++ A      A + P +C  C +       L  H   H GER ++C+ CG+ F  
Sbjct: 912  RFAQSSSLAEHRRLHAVARPQRCSACGKTFRYRSNLLEHQRLHLGERAYRCEHCGKGFFY 971

Query: 671  RGNLRAHFVGHKASPAARAQNSCPICQKKFTNAVTLQQHVRMHLGGQ 717
              ++  H    +A    RA+  CP C K F +    ++H+  H GG+
Sbjct: 972  LSSVLRH---QRAHEPPRAELRCPACLKAFKDPGYFRKHLAAHQGGR 1015



 Score = 58.2 bits (139), Expect = 4e-08
 Identities = 101/431 (23%), Positives = 143/431 (33%), Gaps = 113/431 (26%)

Query: 46  PTEFLAHQNACSTDPPVMVIIGGQENPNNSSASSEPRPEGHNNPQVMDTEHSNPPDSGSS 105
           P +FL   N    +P  +    G+     ++    P P     PQ    ++  PP S   
Sbjct: 30  PFDFLEFLNHQRFEPMELY---GEHAKAVAALPCAPGPPPQPPPQPPPPQYDYPPQS--- 83

Query: 106 VPTDPTWGPERRGEESPGHFLVAATGTAAGGGGGLILASPKLGATPLPPESTPAPPPP-- 163
                T+ P+     S      +++ +++        +S      P  P +  APPPP  
Sbjct: 84  -----TFKPKAEVPSSSSSSSSSSSSSSSSSSSSSSSSSQAKKPDPPLPPAFGAPPPPLF 138

Query: 164 --PPPPPPPGVG--SGHLNIPLILEELRVLQQRQIHQMQMTEQICRQVLLLGSLGQTVGA 219
               P P  G+   SGH +                              L G+L +  G 
Sbjct: 139 DAAFPTPQWGIVDLSGHQH------------------------------LFGNLKR--GG 166

Query: 220 PAS-PSELPGTGTASSTKPLLPLFSPIKPVQTSKTLASSSSSSSSSSG------------ 266
           PAS P   PG G  +     LP  S   P       A++   +    G            
Sbjct: 167 PASGPGVTPGLGAPAGAPGPLPAPSQTPP---GPPAAAACDPTKDDKGYFRRLKYLMERR 223

Query: 267 ------AETPKQAFFHLYHPL--GSQHPFSAGGVGRS-------------HKPTPA---- 301
                  ++ KQ+   + H L    + P+  G  GR+             HK  P     
Sbjct: 224 FPCGVCQKSFKQSSHLVQHMLVHSGERPYECGVCGRTYNHVSSLIRHRRCHKDVPPAAGG 283

Query: 302 ---PSPALP--GSTDQLIASPHLAFPST--TGLLAAQCLGA--ARGLEATASPGLLKPKN 352
              P P LP  G      ++   A PST  +G  A     A  A G  A A  G+  P  
Sbjct: 284 PPQPGPHLPPLGLPAPAASAATAAAPSTVSSGPPATPVAPAPSADGSAAPAGVGVPPPAT 343

Query: 353 GSGELSYGEVMGPLEKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTT 412
           G G+              G   C  C KVF   S L  H   HTGE+P+ C+VC   F  
Sbjct: 344 GGGD--------------GPFACPLCWKVFKKPSHLHQHQIIHTGEKPFSCSVCSKSFNR 389

Query: 413 RGNLKVHFHRH 423
           R +LK H   H
Sbjct: 390 RESLKRHVKTH 400



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 20/52 (38%), Positives = 26/52 (50%)

Query: 632  QCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKA 683
            +C  CL+    P   R H   H G RPF+C  CG  F+    L+ H + HKA
Sbjct: 990  RCPACLKAFKDPGYFRKHLAAHQGGRPFRCSSCGEGFANTYGLKKHRLAHKA 1041



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 20/58 (34%), Positives = 27/58 (46%)

Query: 367  EKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHR 424
            E P    +C  C K F      + HL +H G RP++C+ CG  F     LK H   H+
Sbjct: 983  EPPRAELRCPACLKAFKDPGYFRKHLAAHQGGRPFRCSSCGEGFANTYGLKKHRLAHK 1040



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 29/103 (28%), Positives = 42/103 (40%), Gaps = 18/103 (17%)

Query: 603 GAVAVTSAASGAPTTSAPAPSSSASSGPNQ------------------CVICLRVLSCPR 644
           GA A       AP+ + P P ++A+  P +                  C +C +      
Sbjct: 178 GAPAGAPGPLPAPSQTPPGPPAAAACDPTKDDKGYFRRLKYLMERRFPCGVCQKSFKQSS 237

Query: 645 ALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAA 687
            L  H   H GERP++C VCGR ++   +L  H   HK  P A
Sbjct: 238 HLVQHMLVHSGERPYECGVCGRTYNHVSSLIRHRRCHKDVPPA 280



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 50/236 (21%), Positives = 80/236 (33%), Gaps = 46/236 (19%)

Query: 816  AAAATAGKEMDSNEKTTQQSSLPPP--------PPPDSLDQPQPMEQ-------GSSGVL 860
            ++++++     S+  ++ Q+  P P        PPP   D   P  Q       G   + 
Sbjct: 100  SSSSSSSSSSSSSSSSSSQAKKPDPPLPPAFGAPPPPLFDAAFPTPQWGIVDLSGHQHLF 159

Query: 861  GGKEEGGKPE--------------RSSSPASALTPEGEATSVTLVEELSLQEAMRKEPGE 906
            G  + GG                     PA + TP G   +         +   R+    
Sbjct: 160  GNLKRGGPASGPGVTPGLGAPAGAPGPLPAPSQTPPGPPAAAACDPTKDDKGYFRRLKYL 219

Query: 907  SSSRKACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAHHQV 966
               R  C VC ++F   + L +H   H  E P + C  C + +   ++L +H    H  V
Sbjct: 220  MERRFPCGVCQKSFKQSSHLVQHMLVHSGERP-YECGVCGRTYNHVSSLIRHR-RCHKDV 277

Query: 967  QPFAPHGPQ----------NIAALSLVPGCSPSITSTG-----LSPFPRKDDPTIP 1007
             P A   PQ             A S     +PS  S+G     ++P P  D    P
Sbjct: 278  PPAAGGPPQPGPHLPPLGLPAPAASAATAAAPSTVSSGPPATPVAPAPSADGSAAP 333



 Score = 38.1 bits (87), Expect = 0.042
 Identities = 24/75 (32%), Positives = 35/75 (46%), Gaps = 3/75 (4%)

Query: 895  SLQEAMRKEPGESSSRKACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERAT 954
            +L E  R   GE + R  CE CG+ F   +++  HQ+ H        C  C + F +   
Sbjct: 946  NLLEHQRLHLGERAYR--CEHCGKGFFYLSSVLRHQRAHEPPRAELRCPACLKAFKDPGY 1003

Query: 955  LKKHMLLAHHQVQPF 969
             +KH L AH   +PF
Sbjct: 1004 FRKH-LAAHQGGRPF 1017



 Score = 37.0 bits (84), Expect = 0.093
 Identities = 41/161 (25%), Positives = 65/161 (40%), Gaps = 28/161 (17%)

Query: 816 AAAATAGKEMDSNEKTTQQSSLPPP--PPPDSLDQPQPMEQGSSGVLGGKEEGGKPERSS 873
           AAAA A K+  ++      +  PPP  PP   L  P P    S             E+++
Sbjct: 467 AAAAEAPKDGAAS------APQPPPTFPPGPYLLPPDPPTTDS-------------EKAA 507

Query: 874 SPASALTPEGEATSVTLVEELSLQEAMRKEPGESSSRK-----ACEVCGQAFPSQAALEE 928
           + A+A+        +     L L  A     G S +        C +CG+ F  +  L+ 
Sbjct: 508 AAAAAVVYGAVPVPLLGAHPLLLGGAGTSGAGGSGASVPGKTFCCGICGRGFGRRETLKR 567

Query: 929 HQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAHHQVQPF 969
           H++ H  E P   C  C + F E   L KH ++ H + +P+
Sbjct: 568 HERIHTGEKP-HQCPVCGKRFRESFHLSKHHVV-HTRERPY 606



 Score = 36.6 bits (83), Expect = 0.12
 Identities = 41/192 (21%), Positives = 71/192 (36%), Gaps = 21/192 (10%)

Query: 812 VGTVAAAATAGKEMDSNEKTTQQSSLPPPPPPDSLDQPQPMEQGSSGVLGGKEEGG---- 867
           +G  A AA+A      +  ++   + P  P P +     P   G      G  +G     
Sbjct: 294 LGLPAPAASAATAAAPSTVSSGPPATPVAPAPSADGSAAPAGVGVPPPATGGGDGPFACP 353

Query: 868 -------KPERSSSPASALTPEGEATSVTLVEELSLQEAMRKEPGESSS---RKACEVCG 917
                  KP          T E   +     +  + +E++++     S+   R  C +CG
Sbjct: 354 LCWKVFKKPSHLHQHQIIHTGEKPFSCSVCSKSFNRRESLKRHVKTHSADLLRLPCGICG 413

Query: 918 QAFPSQAALEEHQKTHPKEG-----PLFTCVFCRQGFLERATLKKHMLLAHHQVQPFAPH 972
           +AF   + L +HQ  H   G     P++ C  C + +    +L +H   A H     A  
Sbjct: 414 KAFRDASYLLKHQAAHAGAGAGGPRPVYPCDLCGKSYSAPQSLLRHK--AAHAPPAAAAE 471

Query: 973 GPQNIAALSLVP 984
            P++ AA +  P
Sbjct: 472 APKDGAASAPQP 483



 Score = 33.5 bits (75), Expect = 1.0
 Identities = 15/46 (32%), Positives = 25/46 (54%), Gaps = 1/46 (2%)

Query: 913 CEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKH 958
           C  CG+ F  ++ L EHQ+ H  E   + C  C +GF   +++ +H
Sbjct: 934 CSACGKTFRYRSNLLEHQRLHLGE-RAYRCEHCGKGFFYLSSVLRH 978



 Score = 33.1 bits (74), Expect = 1.3
 Identities = 21/65 (32%), Positives = 26/65 (40%), Gaps = 3/65 (4%)

Query: 896  LQEAMRKEPGESSSRKACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATL 955
            L+     EP  +  R  C  C +AF       +H   H    P F C  C +GF     L
Sbjct: 976  LRHQRAHEPPRAELR--CPACLKAFKDPGYFRKHLAAHQGGRP-FRCSSCGEGFANTYGL 1032

Query: 956  KKHML 960
            KKH L
Sbjct: 1033 KKHRL 1037



 Score = 32.0 bits (71), Expect = 3.0
 Identities = 16/49 (32%), Positives = 24/49 (48%), Gaps = 1/49 (2%)

Query: 913 CEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLL 961
           C VC + F   ++L EH++ H    P   C  C + F  R+ L +H  L
Sbjct: 906 CGVCAKRFAQSSSLAEHRRLHAVARPQ-RCSACGKTFRYRSNLLEHQRL 953



 Score = 31.6 bits (70), Expect = 3.9
 Identities = 22/67 (32%), Positives = 31/67 (46%), Gaps = 4/67 (5%)

Query: 912 ACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLL---AHHQVQP 968
           AC  CG+ FP    +  H++ H  E P + C  C + F     L  H L+   A  ++ P
Sbjct: 670 ACSDCGEHFPDLFHVMSHKEVHMAEKP-YGCDACGKTFGFIENLMWHKLVHQAAPERLLP 728

Query: 969 FAPHGPQ 975
            AP G Q
Sbjct: 729 PAPGGLQ 735



 Score = 31.6 bits (70), Expect = 3.9
 Identities = 16/49 (32%), Positives = 24/49 (48%), Gaps = 1/49 (2%)

Query: 913 CEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLL 961
           C VCG+ F     L +H+  H  E   F C  C + F + ++L +H  L
Sbjct: 878 CGVCGRGFLRSWYLRQHRVVHTGE-RAFKCGVCAKRFAQSSSLAEHRRL 925


>gi|239746371 PREDICTED: similar to zinc finger protein 208 [Homo
           sapiens]
          Length = 1059

 Score = 81.3 bits (199), Expect = 4e-15
 Identities = 149/636 (23%), Positives = 221/636 (34%), Gaps = 83/636 (13%)

Query: 113 GPERRGEESPGHFLVAATGTAAGGGGGLILASPKLGATPLPP----ESTPAPPPPPPPPP 168
           GP + G   P   L A   +AA       ++S    ATP+ P    + + AP     PPP
Sbjct: 283 GPPQPGPHLPPLGLPAPAASAATAAAPSTVSSGP-PATPVAPAPSADGSAAPAGVGVPPP 341

Query: 169 PPGVGSGHLNIPLILEELRVLQQRQIHQMQMTEQICRQVLLLGSLGQTVGAPASPSELPG 228
             G G G    PL  +  +       HQ+  T +   +        ++     S      
Sbjct: 342 ATGGGDGPFACPLCWKVFKKPSHLHQHQIIHTGE---KPFSCSVCSKSFNRRESLKRHVK 398

Query: 229 TGTASSTKPLLPLFSPIKPVQTSKTLASSSSSSSSSSGAETPKQAF-------------F 275
           T +A   +  LP     K  + +  L    ++ + + GA  P+  +              
Sbjct: 399 THSADLLR--LPCGICGKAFRDASYLLKHQAAHAGA-GAGGPRPVYPCDLCGKSYSAPQS 455

Query: 276 HLYHPLGSQHPFSAGGVGRSHKPT-PAPSPALPGSTDQLIASPHLAFPSTTGLLAAQCL- 333
            L H      P +A    +    + P P P  P     L   P           AA  + 
Sbjct: 456 LLRHKAAHAPPAAAAEAPKDGAASAPQPPPTFPPGPYLLPPDPPTTDSEKAAAAAAAVVY 515

Query: 334 GAARGLEATASPGLLKPKNGSGELSYGEVMGPLEKPGGRHKCRFCAKVFGSDSALQIHLR 393
           GA       A P LL     SG    G  +     PG    C  C + FG    L+ H R
Sbjct: 516 GAVPVPLLGAHPLLLGGAGTSGAGGSGASV-----PGKTFCCGICGRGFGRRETLKRHER 570

Query: 394 SHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPH-------VQMNPHPVPEH--LDYV 444
            HTGE+P++C VCG RF    +L  H   H  + P+       V   P  +  H  +  +
Sbjct: 571 IHTGEKPHQCPVCGKRFRESFHLSKHHVVHTRERPYKCELCGKVFGYPQSLTRHRQVHRL 630

Query: 445 ITSSGLPYGMSVPPEKAEEEAATPGGGVERKPLVASTTALSATESLTLLSTSAGTATAPG 504
                L     +P  +    A  PG         AS T+   T+ L+   +  G      
Sbjct: 631 QLPCALAGAAGLPSTQGTPGACGPG---------ASGTSAGPTDGLSYACSDCG----EH 677

Query: 505 LPAFNKFVLMKAVEPKNKADENTPPGSEGSAIS-GVAESSTATRMQLSKLVTSLPSWALL 563
            P     +  K V    K     P G +    + G  E+     +   KLV       LL
Sbjct: 678 FPDLFHVMSHKEVHMAEK-----PYGCDACGKTFGFIEN-----LMWHKLVHQAAPERLL 727

Query: 564 TNHFKSTGSFPFPYVLEPL-GASPSETSKLQQLVEKIDRQGAVAVTSAASGAPTTSAPAP 622
                     P P  L+P  G+S ++ + +       +   AVA  +  SG       A 
Sbjct: 728 P---------PAPGGLQPPDGSSGTDAASVLDNGLAGEVGAAVAALAGVSGGEDAGGAAV 778

Query: 623 SSS---ASSGPNQ--CVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAH 677
           + +   ASSGP +  C  C +       L  H   H   R   C +CG++F+   +L  H
Sbjct: 779 AGAGGGASSGPERFSCATCGQSFKHFLGLVTHKYVHLVRRTLGCGLCGQSFAGAYDLLLH 838

Query: 678 FVGHKASPAARAQNSCPICQKKFTNAVTLQQHVRMH 713
              H+     R    CP+C K+F  A  L +H R H
Sbjct: 839 RRSHRQKRGFR----CPVCGKRFWEAALLMRHQRCH 870



 Score = 70.5 bits (171), Expect = 8e-12
 Identities = 39/113 (34%), Positives = 54/113 (47%), Gaps = 4/113 (3%)

Query: 604 AVAVTSAASGAPT-TSAPAPSSSASSGPNQCVICLRVLSCPRALRLHYGQHGGERPFKCK 662
           A A ++  S AP     P P++    GP  C +C +V   P  L  H   H GE+PF C 
Sbjct: 322 APAPSADGSAAPAGVGVPPPATGGGDGPFACPLCWKVFKKPSHLHQHQIIHTGEKPFSCS 381

Query: 663 VCGRAFSTRGNLRAHFVGHKASPAARAQNSCPICQKKFTNAVTLQQHVRMHLG 715
           VC ++F+ R +L+ H   H A      +  C IC K F +A  L +H   H G
Sbjct: 382 VCSKSFNRRESLKRHVKTHSAD---LLRLPCGICGKAFRDASYLLKHQAAHAG 431



 Score = 64.7 bits (156), Expect = 4e-10
 Identities = 110/432 (25%), Positives = 154/432 (35%), Gaps = 80/432 (18%)

Query: 574 PFPYVLEPLGASPSETSKLQQLVEKIDRQGAVAVTSAAS------GAPTTSAPAPSSSAS 627
           P PY+L P    P+  S+           GAV V    +      GA T+ A    +S  
Sbjct: 489 PGPYLLPP--DPPTTDSEKAAAAAAAVVYGAVPVPLLGAHPLLLGGAGTSGAGGSGASVP 546

Query: 628 SGPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAA 687
                C IC R       L+ H   H GE+P +C VCG+ F    +L  H V H      
Sbjct: 547 GKTFCCGICGRGFGRRETLKRHERIHTGEKPHQCPVCGKRFRESFHLSKHHVVHTRERPY 606

Query: 688 RAQNSCPICQKKFTNAVTLQQHVRMHLGGQIP---NGGTALPEGGGAAQENGSEQSTVSG 744
           +    C +C K F    +L +H ++H   Q+P    G   LP          S Q T   
Sbjct: 607 K----CELCGKVFGYPQSLTRHRQVHRL-QLPCALAGAAGLP----------STQGTPGA 651

Query: 745 AGSFPQQQSQQPSPEEELSEEEEEEDEEEEEDVTDEDSLAGRGSESGGEKAISVRGDS-E 803
            G      S  P+                       D L+   S+ G          S +
Sbjct: 652 CGPGASGTSAGPT-----------------------DGLSYACSDCGEHFPDLFHVMSHK 688

Query: 804 EASGAEEEVGTVAAAATAGK-EMDSNEKTTQQSS----LPPPP----PPDS--------- 845
           E   AE+  G  A   T G  E     K   Q++    LPP P    PPD          
Sbjct: 689 EVHMAEKPYGCDACGKTFGFIENLMWHKLVHQAAPERLLPPAPGGLQPPDGSSGTDAASV 748

Query: 846 LDQPQPMEQGSS-----GVLGGKEEGGKPERSSSPASALTPEGEATSVTLVEELS--LQE 898
           LD     E G++     GV GG++ GG     +   ++  PE   +  T  +     L  
Sbjct: 749 LDNGLAGEVGAAVAALAGVSGGEDAGGAAVAGAGGGASSGPE-RFSCATCGQSFKHFLGL 807

Query: 899 AMRKEPGESSSRKACEVCGQAFPSQAALEEHQKTH-PKEGPLFTCVFCRQGFLERATLKK 957
              K          C +CGQ+F     L  H+++H  K G  F C  C + F E A L +
Sbjct: 808 VTHKYVHLVRRTLGCGLCGQSFAGAYDLLLHRRSHRQKRG--FRCPVCGKRFWEAALLMR 865

Query: 958 HMLLAHHQVQPF 969
           H    H + +P+
Sbjct: 866 HQ-RCHTEQRPY 876



 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 70/274 (25%), Positives = 97/274 (35%), Gaps = 63/274 (22%)

Query: 242 FSPIKPVQTSKTLASSSSSSSSSSGAETPKQAFFHLYHPLGSQHPFSAGGVGRSHKPTPA 301
           F P   V +S + +SSSSSSSSSS +                    S+    ++ KP P 
Sbjct: 85  FKPKAEVPSSSSSSSSSSSSSSSSSSS-------------------SSSSSSQAKKPDPP 125

Query: 302 PSPAL----PGSTDQLIASPHLAFPSTTGLLAAQCLGAARGLEATASPGLLKPKNGSGEL 357
             PA     P   D    +P       +G       G  +     + PG+  P  G+   
Sbjct: 126 LPPAFGAPPPPLFDAAFPTPQWGIVDLSG--HQHLFGNLKRGGPASGPGVT-PGLGAPAG 182

Query: 358 SYGEVMGPLEKPGG--------------------------RHKCRFCAKVFGSDSALQIH 391
           + G +  P + P G                          R  C  C K F   S L  H
Sbjct: 183 APGPLPAPSQTPPGPPAAAACDPTKDDKGYFRRLKYLMERRFPCGVCQKSFKQSSHLVQH 242

Query: 392 LRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPHVQMNPHPVPEHLDYVITSSGLP 451
           +  H+GERPY+C VCG  +    +L  H   H++  P     P P P HL         P
Sbjct: 243 MLVHSGERPYECGVCGRTYNHVSSLIRHRRCHKDVPPAAGGPPQPGP-HLP--------P 293

Query: 452 YGMSVPPEKAEEEAA--TPGGGVERKPLVASTTA 483
            G+  P   A   AA  T   G    P+  + +A
Sbjct: 294 LGLPAPAASAATAAAPSTVSSGPPATPVAPAPSA 327



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 91/407 (22%), Positives = 144/407 (35%), Gaps = 49/407 (12%)

Query: 333  LGAARGLEAT-ASPGLLKPKNGSGELSYGEVMGPLEKPGGRHKCRFCAKVFGSDSALQIH 391
            L  A GL +T  +PG   P       + G   GP +  G  + C  C + F     +  H
Sbjct: 636  LAGAAGLPSTQGTPGACGPG------ASGTSAGPTD--GLSYACSDCGEHFPDLFHVMSH 687

Query: 392  LRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPHVQMNPHPVPEHLDYVITSSGLP 451
               H  E+PY C+ CG  F    NL  H   H+             PE L         P
Sbjct: 688  KEVHMAEKPYGCDACGKTFGFIENLMWHKLVHQA-----------APERL-----LPPAP 731

Query: 452  YGMSVPPEKAEEEAATP---GGGVERKPLVASTTALSATESL---TLLSTSAGTATAPGL 505
             G+  P   +  +AA+    G   E    VA+   +S  E      +     G ++ P  
Sbjct: 732  GGLQPPDGSSGTDAASVLDNGLAGEVGAAVAALAGVSGGEDAGGAAVAGAGGGASSGPER 791

Query: 506  -------PAFNKFVLMKAVEPKNKADENTPPGSEGSAISGVAESSTATRMQLSKLVTSLP 558
                    +F  F+ +   +  +        G  G + +G  +     R    K     P
Sbjct: 792  FSCATCGQSFKHFLGLVTHKYVHLVRRTLGCGLCGQSFAGAYDLLLHRRSHRQKRGFRCP 851

Query: 559  S-----W--ALLTNHFKS-TGSFPFPYVLEPLGASPSETSKLQQLVEKIDRQGAVAVTSA 610
                  W  ALL  H +  T   P+   +   G   S   +  ++V   +R     V + 
Sbjct: 852  VCGKRFWEAALLMRHQRCHTEQRPYRCGVCGRGFLRSWYLRQHRVVHTGERAFKCGVCAK 911

Query: 611  ASGAPTTSAPAPSSSASSGPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFST 670
                 ++ A      A + P +C  C +       L  H   H GER ++C+ CG+ F  
Sbjct: 912  RFAQSSSLAEHRRLHAVARPQRCSACGKTFRYRSNLLEHQRLHLGERAYRCEHCGKGFFY 971

Query: 671  RGNLRAHFVGHKASPAARAQNSCPICQKKFTNAVTLQQHVRMHLGGQ 717
              ++  H    +A    R +  CP C K F +    ++H+  H GG+
Sbjct: 972  LSSVLRH---QRAHEPPRPELRCPACLKAFKDPGYFRKHLAAHQGGR 1015



 Score = 58.2 bits (139), Expect = 4e-08
 Identities = 101/431 (23%), Positives = 143/431 (33%), Gaps = 113/431 (26%)

Query: 46  PTEFLAHQNACSTDPPVMVIIGGQENPNNSSASSEPRPEGHNNPQVMDTEHSNPPDSGSS 105
           P +FL   N    +P  +    G+     ++    P P     PQ    ++  PP S   
Sbjct: 30  PFDFLEFLNHQRFEPMELY---GEHAKAVAALPCAPGPPPQPPPQPPPPQYDYPPQS--- 83

Query: 106 VPTDPTWGPERRGEESPGHFLVAATGTAAGGGGGLILASPKLGATPLPPESTPAPPPP-- 163
                T+ P+     S      +++ +++        +S      P  P +  APPPP  
Sbjct: 84  -----TFKPKAEVPSSSSSSSSSSSSSSSSSSSSSSSSSQAKKPDPPLPPAFGAPPPPLF 138

Query: 164 --PPPPPPPGVG--SGHLNIPLILEELRVLQQRQIHQMQMTEQICRQVLLLGSLGQTVGA 219
               P P  G+   SGH +                              L G+L +  G 
Sbjct: 139 DAAFPTPQWGIVDLSGHQH------------------------------LFGNLKR--GG 166

Query: 220 PAS-PSELPGTGTASSTKPLLPLFSPIKPVQTSKTLASSSSSSSSSSG------------ 266
           PAS P   PG G  +     LP  S   P       A++   +    G            
Sbjct: 167 PASGPGVTPGLGAPAGAPGPLPAPSQTPP---GPPAAAACDPTKDDKGYFRRLKYLMERR 223

Query: 267 ------AETPKQAFFHLYHPL--GSQHPFSAGGVGRS-------------HKPTPA---- 301
                  ++ KQ+   + H L    + P+  G  GR+             HK  P     
Sbjct: 224 FPCGVCQKSFKQSSHLVQHMLVHSGERPYECGVCGRTYNHVSSLIRHRRCHKDVPPAAGG 283

Query: 302 ---PSPALP--GSTDQLIASPHLAFPST--TGLLAAQCLGA--ARGLEATASPGLLKPKN 352
              P P LP  G      ++   A PST  +G  A     A  A G  A A  G+  P  
Sbjct: 284 PPQPGPHLPPLGLPAPAASAATAAAPSTVSSGPPATPVAPAPSADGSAAPAGVGVPPPAT 343

Query: 353 GSGELSYGEVMGPLEKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTT 412
           G G+              G   C  C KVF   S L  H   HTGE+P+ C+VC   F  
Sbjct: 344 GGGD--------------GPFACPLCWKVFKKPSHLHQHQIIHTGEKPFSCSVCSKSFNR 389

Query: 413 RGNLKVHFHRH 423
           R +LK H   H
Sbjct: 390 RESLKRHVKTH 400



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 20/52 (38%), Positives = 26/52 (50%)

Query: 632  QCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKA 683
            +C  CL+    P   R H   H G RPF+C  CG  F+    L+ H + HKA
Sbjct: 990  RCPACLKAFKDPGYFRKHLAAHQGGRPFRCSSCGEGFANTYGLKKHRLAHKA 1041



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 29/103 (28%), Positives = 42/103 (40%), Gaps = 18/103 (17%)

Query: 603 GAVAVTSAASGAPTTSAPAPSSSASSGPNQ------------------CVICLRVLSCPR 644
           GA A       AP+ + P P ++A+  P +                  C +C +      
Sbjct: 178 GAPAGAPGPLPAPSQTPPGPPAAAACDPTKDDKGYFRRLKYLMERRFPCGVCQKSFKQSS 237

Query: 645 ALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAA 687
            L  H   H GERP++C VCGR ++   +L  H   HK  P A
Sbjct: 238 HLVQHMLVHSGERPYECGVCGRTYNHVSSLIRHRRCHKDVPPA 280



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 20/58 (34%), Positives = 27/58 (46%)

Query: 367  EKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHR 424
            E P    +C  C K F      + HL +H G RP++C+ CG  F     LK H   H+
Sbjct: 983  EPPRPELRCPACLKAFKDPGYFRKHLAAHQGGRPFRCSSCGEGFANTYGLKKHRLAHK 1040



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 25/75 (33%), Positives = 36/75 (48%), Gaps = 3/75 (4%)

Query: 895  SLQEAMRKEPGESSSRKACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERAT 954
            +L E  R   GE + R  CE CG+ F   +++  HQ+ H    P   C  C + F +   
Sbjct: 946  NLLEHQRLHLGERAYR--CEHCGKGFFYLSSVLRHQRAHEPPRPELRCPACLKAFKDPGY 1003

Query: 955  LKKHMLLAHHQVQPF 969
             +KH L AH   +PF
Sbjct: 1004 FRKH-LAAHQGGRPF 1017



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 50/236 (21%), Positives = 80/236 (33%), Gaps = 46/236 (19%)

Query: 816  AAAATAGKEMDSNEKTTQQSSLPPP--------PPPDSLDQPQPMEQ-------GSSGVL 860
            ++++++     S+  ++ Q+  P P        PPP   D   P  Q       G   + 
Sbjct: 100  SSSSSSSSSSSSSSSSSSQAKKPDPPLPPAFGAPPPPLFDAAFPTPQWGIVDLSGHQHLF 159

Query: 861  GGKEEGGKPE--------------RSSSPASALTPEGEATSVTLVEELSLQEAMRKEPGE 906
            G  + GG                     PA + TP G   +         +   R+    
Sbjct: 160  GNLKRGGPASGPGVTPGLGAPAGAPGPLPAPSQTPPGPPAAAACDPTKDDKGYFRRLKYL 219

Query: 907  SSSRKACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAHHQV 966
               R  C VC ++F   + L +H   H  E P + C  C + +   ++L +H    H  V
Sbjct: 220  MERRFPCGVCQKSFKQSSHLVQHMLVHSGERP-YECGVCGRTYNHVSSLIRHR-RCHKDV 277

Query: 967  QPFAPHGPQ----------NIAALSLVPGCSPSITSTG-----LSPFPRKDDPTIP 1007
             P A   PQ             A S     +PS  S+G     ++P P  D    P
Sbjct: 278  PPAAGGPPQPGPHLPPLGLPAPAASAATAAAPSTVSSGPPATPVAPAPSADGSAAP 333



 Score = 37.0 bits (84), Expect = 0.093
 Identities = 41/161 (25%), Positives = 65/161 (40%), Gaps = 28/161 (17%)

Query: 816 AAAATAGKEMDSNEKTTQQSSLPPP--PPPDSLDQPQPMEQGSSGVLGGKEEGGKPERSS 873
           AAAA A K+  ++      +  PPP  PP   L  P P    S             E+++
Sbjct: 467 AAAAEAPKDGAAS------APQPPPTFPPGPYLLPPDPPTTDS-------------EKAA 507

Query: 874 SPASALTPEGEATSVTLVEELSLQEAMRKEPGESSSRK-----ACEVCGQAFPSQAALEE 928
           + A+A+        +     L L  A     G S +        C +CG+ F  +  L+ 
Sbjct: 508 AAAAAVVYGAVPVPLLGAHPLLLGGAGTSGAGGSGASVPGKTFCCGICGRGFGRRETLKR 567

Query: 929 HQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAHHQVQPF 969
           H++ H  E P   C  C + F E   L KH ++ H + +P+
Sbjct: 568 HERIHTGEKP-HQCPVCGKRFRESFHLSKHHVV-HTRERPY 606



 Score = 36.6 bits (83), Expect = 0.12
 Identities = 41/192 (21%), Positives = 71/192 (36%), Gaps = 21/192 (10%)

Query: 812 VGTVAAAATAGKEMDSNEKTTQQSSLPPPPPPDSLDQPQPMEQGSSGVLGGKEEGG---- 867
           +G  A AA+A      +  ++   + P  P P +     P   G      G  +G     
Sbjct: 294 LGLPAPAASAATAAAPSTVSSGPPATPVAPAPSADGSAAPAGVGVPPPATGGGDGPFACP 353

Query: 868 -------KPERSSSPASALTPEGEATSVTLVEELSLQEAMRKEPGESSS---RKACEVCG 917
                  KP          T E   +     +  + +E++++     S+   R  C +CG
Sbjct: 354 LCWKVFKKPSHLHQHQIIHTGEKPFSCSVCSKSFNRRESLKRHVKTHSADLLRLPCGICG 413

Query: 918 QAFPSQAALEEHQKTHPKEG-----PLFTCVFCRQGFLERATLKKHMLLAHHQVQPFAPH 972
           +AF   + L +HQ  H   G     P++ C  C + +    +L +H   A H     A  
Sbjct: 414 KAFRDASYLLKHQAAHAGAGAGGPRPVYPCDLCGKSYSAPQSLLRHK--AAHAPPAAAAE 471

Query: 973 GPQNIAALSLVP 984
            P++ AA +  P
Sbjct: 472 APKDGAASAPQP 483



 Score = 34.7 bits (78), Expect = 0.46
 Identities = 18/56 (32%), Positives = 29/56 (51%), Gaps = 2/56 (3%)

Query: 913 CEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAHHQVQP 968
           C  CG+ F  ++ L EHQ+ H  E   + C  C +GF   +++ +H   AH   +P
Sbjct: 934 CSACGKTFRYRSNLLEHQRLHLGE-RAYRCEHCGKGFFYLSSVLRHQ-RAHEPPRP 987



 Score = 32.3 bits (72), Expect = 2.3
 Identities = 17/48 (35%), Positives = 20/48 (41%), Gaps = 1/48 (2%)

Query: 913  CEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHML 960
            C  C +AF       +H   H    P F C  C +GF     LKKH L
Sbjct: 991  CPACLKAFKDPGYFRKHLAAHQGGRP-FRCSSCGEGFANTYGLKKHRL 1037



 Score = 32.0 bits (71), Expect = 3.0
 Identities = 16/49 (32%), Positives = 24/49 (48%), Gaps = 1/49 (2%)

Query: 913 CEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLL 961
           C VC + F   ++L EH++ H    P   C  C + F  R+ L +H  L
Sbjct: 906 CGVCAKRFAQSSSLAEHRRLHAVARPQ-RCSACGKTFRYRSNLLEHQRL 953



 Score = 31.6 bits (70), Expect = 3.9
 Identities = 22/67 (32%), Positives = 31/67 (46%), Gaps = 4/67 (5%)

Query: 912 ACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLL---AHHQVQP 968
           AC  CG+ FP    +  H++ H  E P + C  C + F     L  H L+   A  ++ P
Sbjct: 670 ACSDCGEHFPDLFHVMSHKEVHMAEKP-YGCDACGKTFGFIENLMWHKLVHQAAPERLLP 728

Query: 969 FAPHGPQ 975
            AP G Q
Sbjct: 729 PAPGGLQ 735



 Score = 31.6 bits (70), Expect = 3.9
 Identities = 16/49 (32%), Positives = 24/49 (48%), Gaps = 1/49 (2%)

Query: 913 CEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLL 961
           C VCG+ F     L +H+  H  E   F C  C + F + ++L +H  L
Sbjct: 878 CGVCGRGFLRSWYLRQHRVVHTGE-RAFKCGVCAKRFAQSSSLAEHRRL 925



 Score = 31.6 bits (70), Expect = 3.9
 Identities = 17/57 (29%), Positives = 25/57 (43%), Gaps = 1/57 (1%)

Query: 373  HKCRFCAKVFGSDSALQIHLRSHTGERP-YKCNVCGNRFTTRGNLKVHFHRHREKYP 428
            ++C  C K F   S++  H R+H   RP  +C  C   F   G  + H   H+   P
Sbjct: 960  YRCEHCGKGFFYLSSVLRHQRAHEPPRPELRCPACLKAFKDPGYFRKHLAAHQGGRP 1016


>gi|153791350 replication initiator 1 isoform 1 [Homo sapiens]
          Length = 567

 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 101/429 (23%), Positives = 149/429 (34%), Gaps = 64/429 (14%)

Query: 294 RSHKPTPAPSPALPGSTDQLIASPHLAFPSTTGLLAAQCLGAARGLEATASPGLLKPKNG 353
           R H P P   P + G+  +       +F     L+A + +  A  LE  A+  L      
Sbjct: 166 RCHPPAPEARPFICGNCGR-------SFAQWDQLVAHKRVHVAEALEEAAAKAL------ 212

Query: 354 SGELSYGEVMGPLEKPGGR-----HKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGN 408
            G    G       +PGG       +C  C K F     L  H R HTGERP++C  CG 
Sbjct: 213 -GPRPRGRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPNLIAHRRVHTGERPHQCPECGK 271

Query: 409 RFTTRGNLKVHFHRHREKYPHVQMNPHPVPEHLDYVITSSGLPYGMSVPPEKAEEEA-AT 467
           RFT +  L  H   H  + P+          H   +++ S +        +++E  A A 
Sbjct: 272 RFTNKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIH-------KRSEGSAQAA 324

Query: 468 PGGGVERKPLVASTTALSATESLTLLSTSAGTATAPGLPAFNKFVLMKAVEPKNKADENT 527
           PG G  + P     +A   T ++ L          PG P            P++  D   
Sbjct: 325 PGPGSPQLPAGPQESAAEPTPAVPL---KPAQEPPPGAP------------PEHPQDPIE 369

Query: 528 PPGSEGSAISGVAESSTATRMQLSKLVTSLPSWALLTNHFKSTGSFPFPYVLEPLGASPS 587
            P S  S              +L +         L  +  + TG  PF       G +  
Sbjct: 370 APPSLYSC------DDCGRSFRLERF--------LRAHQRQHTGERPF--TCAECGKNFG 413

Query: 588 ETSKL--QQLVEKIDRQGAVAVTSAASGAPTTSAPAPSSSASSGPNQCVICLRVLSCPRA 645
           + + L     V   +R  A           +  A      A   P  C  C +       
Sbjct: 414 KKTHLVAHSRVHSGERPFACEECGRRFSQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPY 473

Query: 646 LRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARAQNSCPICQKKFTNAVT 705
           L  H   H GE+P+ C  CG+AFS + NL    V H+         +CP C + F+    
Sbjct: 474 LAAHRRIHTGEKPYVCPDCGKAFSQKSNL----VSHRRIHTGERPYACPDCDRSFSQKSN 529

Query: 706 LQQHVRMHL 714
           L  H + H+
Sbjct: 530 LITHRKSHI 538



 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 86/381 (22%), Positives = 136/381 (35%), Gaps = 56/381 (14%)

Query: 591 KLQQLVEKIDRQGAVAVTSAASGAPTTSAPAPSSSASSGPNQCVICLRVLSCPRALRLHY 650
           K   + E ++   A A+     G P  +AP P   A   P QC  C +       L  H 
Sbjct: 196 KRVHVAEALEEAAAKALGPRPRGRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPNLIAHR 255

Query: 651 GQHGGERPFKCKVCGRAFSTRGNLRAH---FVGHKASPAARAQNSCPICQKKFTNAVTLQ 707
             H GERP +C  CG+ F+ +  L +H     G K  P       C  C ++F +   L 
Sbjct: 256 RVHTGERPHQCPECGKRFTNKPYLTSHRRIHTGEKPYP-------CKECGRRFRHKPNLL 308

Query: 708 QHVRMHLGGQIPNGGTALPEGGGAAQENGSEQSTVSGAGSFPQQQSQQPSPEEELSEEEE 767
            H ++H   +            G+AQ      S    AG  PQ+ + +P+P   L   +E
Sbjct: 309 SHSKIHKRSE------------GSAQAAPGPGSPQLPAG--PQESAAEPTPAVPLKPAQE 354

Query: 768 EEDEEEEEDVTDEDSLAGRGSESGGEKAISVRGDSEEASGAEEEVGTVA-AAATAGKEMD 826
                  E   D    A     S  +   S R +    +   +  G      A  GK   
Sbjct: 355 PPPGAPPEHPQDPIE-APPSLYSCDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFG 413

Query: 827 SNEKTTQQSSLPPPPPPDSLDQ-PQPMEQGSSGVLGGKEEGGKPERSSSPASALTPEGEA 885
                   S +     P + ++  +   QGS   L        P+R       + P+   
Sbjct: 414 KKTHLVAHSRVHSGERPFACEECGRRFSQGSH--LAAHRRDHAPDRPF-----VCPD--- 463

Query: 886 TSVTLVEELSLQEAMRKEPGESSSRK--------ACEVCGQAFPSQAALEEHQKTHPKEG 937
                       +A R +P  ++ R+         C  CG+AF  ++ L  H++ H  E 
Sbjct: 464 ----------CGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAFSQKSNLVSHRRIHTGER 513

Query: 938 PLFTCVFCRQGFLERATLKKH 958
           P + C  C + F +++ L  H
Sbjct: 514 P-YACPDCDRSFSQKSNLITH 533



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 82/358 (22%), Positives = 116/358 (32%), Gaps = 65/358 (18%)

Query: 375 CRFCAKVFGSDSALQIHLRSHTG-ERPYKCNVCGNRFTTRGNLKVHFHRHREKYPHVQMN 433
           C  C + F    AL +HLR+H+  +RP  C  C  RF  R  L+ H  R           
Sbjct: 118 CHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWRRKQLRAHLRRCHP-------- 169

Query: 434 PHPVPEHLDYVITSSGLPYGM--------SVPPEKAEEEAATPGGGVERKPLVASTTALS 485
             P PE   ++  + G  +           V   +A EEAA    G   +          
Sbjct: 170 --PAPEARPFICGNCGRSFAQWDQLVAHKRVHVAEALEEAAAKALGPRPR---------- 217

Query: 486 ATESLTLLSTSAGTATAPGLPAFNKFVLMKAVEPKNKADENTPPGSEGSAISGVAESSTA 545
                      A TA  PG  A ++         + +   N         +       T 
Sbjct: 218 --------GRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPN---------LIAHRRVHTG 260

Query: 546 TR----MQLSKLVTSLPSWALLTNHFK-STGSFPFPYVLEPLGASPSETSKLQQLVEKID 600
            R     +  K  T+ P    LT+H +  TG  P+P   +  G        L    +   
Sbjct: 261 ERPHQCPECGKRFTNKP---YLTSHRRIHTGEKPYP--CKECGRRFRHKPNLLSHSKIHK 315

Query: 601 RQGAVAVTSAASGAPTTSAPAPSSSASSGPNQCVICLRVLSCPRALRLHYGQHGGERP-- 658
           R    A  +   G+P    PA    +++ P   V        P      + Q   E P  
Sbjct: 316 RSEGSAQAAPGPGSP--QLPAGPQESAAEPTPAVPLKPAQEPPPGAPPEHPQDPIEAPPS 373

Query: 659 -FKCKVCGRAFSTRGNLRAHFVGHKASPAARAQNSCPICQKKFTNAVTLQQHVRMHLG 715
            + C  CGR+F     LRAH   H          +C  C K F     L  H R+H G
Sbjct: 374 LYSCDDCGRSFRLERFLRAHQRQH----TGERPFTCAECGKNFGKKTHLVAHSRVHSG 427



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 4/84 (4%)

Query: 630 PNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARA 689
           P  C  C +  S    L  H   H GERP+ C  C R+FS + NL    + H+ S     
Sbjct: 486 PYVCPDCGKAFSQKSNLVSHRRIHTGERPYACPDCDRSFSQKSNL----ITHRKSHIRDG 541

Query: 690 QNSCPICQKKFTNAVTLQQHVRMH 713
              C IC + F +   L  H + H
Sbjct: 542 AFCCAICGQTFDDEERLLAHQKKH 565



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 32/120 (26%), Positives = 50/120 (41%), Gaps = 14/120 (11%)

Query: 863 KEEGGKPERSSSPASALTPEG-EATSVTLVEELSLQEAMRKEPGESS-----------SR 910
           K   G  + +  P S   P G + ++      + L+ A    PG              S 
Sbjct: 315 KRSEGSAQAAPGPGSPQLPAGPQESAAEPTPAVPLKPAQEPPPGAPPEHPQDPIEAPPSL 374

Query: 911 KACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAHHQVQPFA 970
            +C+ CG++F  +  L  HQ+ H  E P FTC  C + F ++  L  H  + H   +PFA
Sbjct: 375 YSCDDCGRSFRLERFLRAHQRQHTGERP-FTCAECGKNFGKKTHLVAHSRV-HSGERPFA 432



 Score = 39.3 bits (90), Expect = 0.019
 Identities = 21/69 (30%), Positives = 27/69 (39%)

Query: 367 EKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREK 426
           + PG  H+C  C + F    AL +H R      P  C  CG RF     L +H   H   
Sbjct: 51  QAPGRAHRCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALHRQVHAAA 110

Query: 427 YPHVQMNPH 435
            P +    H
Sbjct: 111 TPDLGFACH 119



 Score = 39.3 bits (90), Expect = 0.019
 Identities = 26/85 (30%), Positives = 36/85 (42%), Gaps = 6/85 (7%)

Query: 630 PNQCVICLRVLSCPRALRLHYGQHGGERP---FKCKVCGRAFSTRGNLRAHFVGHKASPA 686
           P  C  C R       L LH   H    P   F C +CG++F     L  H   H A   
Sbjct: 84  PLPCPECGRRFRHAPFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSA--- 140

Query: 687 ARAQNSCPICQKKFTNAVTLQQHVR 711
           A+   +CP C+++F     L+ H+R
Sbjct: 141 AKRPIACPKCERRFWRRKQLRAHLR 165



 Score = 38.9 bits (89), Expect = 0.025
 Identities = 29/103 (28%), Positives = 39/103 (37%), Gaps = 1/103 (0%)

Query: 617 TSAPAPSSSASSGPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRA 676
           TS     + A    ++C  C R      AL LH  +     P  C  CGR F     L  
Sbjct: 43  TSVAQSGAQAPGRAHRCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLAL 102

Query: 677 HFVGHKASPAARAQNSCPICQKKFTNAVTLQQHVRMHLGGQIP 719
           H   H A+       +C +C + F   V L  H+R H   + P
Sbjct: 103 HRQVH-AAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRP 144



 Score = 37.0 bits (84), Expect = 0.093
 Identities = 17/52 (32%), Positives = 23/52 (44%)

Query: 912 ACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAH 963
           AC +CGQ+F    AL  H + H        C  C + F  R  L+ H+   H
Sbjct: 117 ACHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWRRKQLRAHLRRCH 168



 Score = 36.2 bits (82), Expect = 0.16
 Identities = 25/85 (29%), Positives = 28/85 (32%), Gaps = 31/85 (36%)

Query: 367 EKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCN---------------------- 404
           EKP   + C  C K F   S L  H R HTGERPY C                       
Sbjct: 484 EKP---YVCPDCGKAFSQKSNLVSHRRIHTGERPYACPDCDRSFSQKSNLITHRKSHIRD 540

Query: 405 ------VCGNRFTTRGNLKVHFHRH 423
                 +CG  F     L  H  +H
Sbjct: 541 GAFCCAICGQTFDDEERLLAHQKKH 565



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 2/58 (3%)

Query: 913 CEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAHHQVQPFA 970
           C  CG+AF  +  L  H++ H  E P + C  C + F +++ L  H  + H   +P+A
Sbjct: 461 CPDCGKAFRHKPYLAAHRRIHTGEKP-YVCPDCGKAFSQKSNLVSHRRI-HTGERPYA 516



 Score = 33.9 bits (76), Expect = 0.79
 Identities = 16/47 (34%), Positives = 25/47 (53%), Gaps = 1/47 (2%)

Query: 912 ACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKH 958
           AC  C ++F  ++ L  H+K+H ++G  F C  C Q F +   L  H
Sbjct: 516 ACPDCDRSFSQKSNLITHRKSHIRDG-AFCCAICGQTFDDEERLLAH 561



 Score = 33.1 bits (74), Expect = 1.3
 Identities = 22/77 (28%), Positives = 31/77 (40%), Gaps = 11/77 (14%)

Query: 913 CEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLL----------A 962
           C  CG+ F ++  L  H++ H  E P + C  C + F  +  L  H  +          A
Sbjct: 266 CPECGKRFTNKPYLTSHRRIHTGEKP-YPCKECGRRFRHKPNLLSHSKIHKRSEGSAQAA 324

Query: 963 HHQVQPFAPHGPQNIAA 979
                P  P GPQ  AA
Sbjct: 325 PGPGSPQLPAGPQESAA 341


>gi|153792539 replication initiator 1 isoform 1 [Homo sapiens]
          Length = 567

 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 101/429 (23%), Positives = 149/429 (34%), Gaps = 64/429 (14%)

Query: 294 RSHKPTPAPSPALPGSTDQLIASPHLAFPSTTGLLAAQCLGAARGLEATASPGLLKPKNG 353
           R H P P   P + G+  +       +F     L+A + +  A  LE  A+  L      
Sbjct: 166 RCHPPAPEARPFICGNCGR-------SFAQWDQLVAHKRVHVAEALEEAAAKAL------ 212

Query: 354 SGELSYGEVMGPLEKPGGR-----HKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGN 408
            G    G       +PGG       +C  C K F     L  H R HTGERP++C  CG 
Sbjct: 213 -GPRPRGRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPNLIAHRRVHTGERPHQCPECGK 271

Query: 409 RFTTRGNLKVHFHRHREKYPHVQMNPHPVPEHLDYVITSSGLPYGMSVPPEKAEEEA-AT 467
           RFT +  L  H   H  + P+          H   +++ S +        +++E  A A 
Sbjct: 272 RFTNKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIH-------KRSEGSAQAA 324

Query: 468 PGGGVERKPLVASTTALSATESLTLLSTSAGTATAPGLPAFNKFVLMKAVEPKNKADENT 527
           PG G  + P     +A   T ++ L          PG P            P++  D   
Sbjct: 325 PGPGSPQLPAGPQESAAEPTPAVPL---KPAQEPPPGAP------------PEHPQDPIE 369

Query: 528 PPGSEGSAISGVAESSTATRMQLSKLVTSLPSWALLTNHFKSTGSFPFPYVLEPLGASPS 587
            P S  S              +L +         L  +  + TG  PF       G +  
Sbjct: 370 APPSLYSC------DDCGRSFRLERF--------LRAHQRQHTGERPF--TCAECGKNFG 413

Query: 588 ETSKL--QQLVEKIDRQGAVAVTSAASGAPTTSAPAPSSSASSGPNQCVICLRVLSCPRA 645
           + + L     V   +R  A           +  A      A   P  C  C +       
Sbjct: 414 KKTHLVAHSRVHSGERPFACEECGRRFSQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPY 473

Query: 646 LRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARAQNSCPICQKKFTNAVT 705
           L  H   H GE+P+ C  CG+AFS + NL    V H+         +CP C + F+    
Sbjct: 474 LAAHRRIHTGEKPYVCPDCGKAFSQKSNL----VSHRRIHTGERPYACPDCDRSFSQKSN 529

Query: 706 LQQHVRMHL 714
           L  H + H+
Sbjct: 530 LITHRKSHI 538



 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 86/381 (22%), Positives = 136/381 (35%), Gaps = 56/381 (14%)

Query: 591 KLQQLVEKIDRQGAVAVTSAASGAPTTSAPAPSSSASSGPNQCVICLRVLSCPRALRLHY 650
           K   + E ++   A A+     G P  +AP P   A   P QC  C +       L  H 
Sbjct: 196 KRVHVAEALEEAAAKALGPRPRGRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPNLIAHR 255

Query: 651 GQHGGERPFKCKVCGRAFSTRGNLRAH---FVGHKASPAARAQNSCPICQKKFTNAVTLQ 707
             H GERP +C  CG+ F+ +  L +H     G K  P       C  C ++F +   L 
Sbjct: 256 RVHTGERPHQCPECGKRFTNKPYLTSHRRIHTGEKPYP-------CKECGRRFRHKPNLL 308

Query: 708 QHVRMHLGGQIPNGGTALPEGGGAAQENGSEQSTVSGAGSFPQQQSQQPSPEEELSEEEE 767
            H ++H   +            G+AQ      S    AG  PQ+ + +P+P   L   +E
Sbjct: 309 SHSKIHKRSE------------GSAQAAPGPGSPQLPAG--PQESAAEPTPAVPLKPAQE 354

Query: 768 EEDEEEEEDVTDEDSLAGRGSESGGEKAISVRGDSEEASGAEEEVGTVA-AAATAGKEMD 826
                  E   D    A     S  +   S R +    +   +  G      A  GK   
Sbjct: 355 PPPGAPPEHPQDPIE-APPSLYSCDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFG 413

Query: 827 SNEKTTQQSSLPPPPPPDSLDQ-PQPMEQGSSGVLGGKEEGGKPERSSSPASALTPEGEA 885
                   S +     P + ++  +   QGS   L        P+R       + P+   
Sbjct: 414 KKTHLVAHSRVHSGERPFACEECGRRFSQGSH--LAAHRRDHAPDRPF-----VCPD--- 463

Query: 886 TSVTLVEELSLQEAMRKEPGESSSRK--------ACEVCGQAFPSQAALEEHQKTHPKEG 937
                       +A R +P  ++ R+         C  CG+AF  ++ L  H++ H  E 
Sbjct: 464 ----------CGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAFSQKSNLVSHRRIHTGER 513

Query: 938 PLFTCVFCRQGFLERATLKKH 958
           P + C  C + F +++ L  H
Sbjct: 514 P-YACPDCDRSFSQKSNLITH 533



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 82/358 (22%), Positives = 116/358 (32%), Gaps = 65/358 (18%)

Query: 375 CRFCAKVFGSDSALQIHLRSHTG-ERPYKCNVCGNRFTTRGNLKVHFHRHREKYPHVQMN 433
           C  C + F    AL +HLR+H+  +RP  C  C  RF  R  L+ H  R           
Sbjct: 118 CHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWRRKQLRAHLRRCHP-------- 169

Query: 434 PHPVPEHLDYVITSSGLPYGM--------SVPPEKAEEEAATPGGGVERKPLVASTTALS 485
             P PE   ++  + G  +           V   +A EEAA    G   +          
Sbjct: 170 --PAPEARPFICGNCGRSFAQWDQLVAHKRVHVAEALEEAAAKALGPRPR---------- 217

Query: 486 ATESLTLLSTSAGTATAPGLPAFNKFVLMKAVEPKNKADENTPPGSEGSAISGVAESSTA 545
                      A TA  PG  A ++         + +   N         +       T 
Sbjct: 218 --------GRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPN---------LIAHRRVHTG 260

Query: 546 TR----MQLSKLVTSLPSWALLTNHFK-STGSFPFPYVLEPLGASPSETSKLQQLVEKID 600
            R     +  K  T+ P    LT+H +  TG  P+P   +  G        L    +   
Sbjct: 261 ERPHQCPECGKRFTNKP---YLTSHRRIHTGEKPYP--CKECGRRFRHKPNLLSHSKIHK 315

Query: 601 RQGAVAVTSAASGAPTTSAPAPSSSASSGPNQCVICLRVLSCPRALRLHYGQHGGERP-- 658
           R    A  +   G+P    PA    +++ P   V        P      + Q   E P  
Sbjct: 316 RSEGSAQAAPGPGSP--QLPAGPQESAAEPTPAVPLKPAQEPPPGAPPEHPQDPIEAPPS 373

Query: 659 -FKCKVCGRAFSTRGNLRAHFVGHKASPAARAQNSCPICQKKFTNAVTLQQHVRMHLG 715
            + C  CGR+F     LRAH   H          +C  C K F     L  H R+H G
Sbjct: 374 LYSCDDCGRSFRLERFLRAHQRQH----TGERPFTCAECGKNFGKKTHLVAHSRVHSG 427



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 4/84 (4%)

Query: 630 PNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARA 689
           P  C  C +  S    L  H   H GERP+ C  C R+FS + NL    + H+ S     
Sbjct: 486 PYVCPDCGKAFSQKSNLVSHRRIHTGERPYACPDCDRSFSQKSNL----ITHRKSHIRDG 541

Query: 690 QNSCPICQKKFTNAVTLQQHVRMH 713
              C IC + F +   L  H + H
Sbjct: 542 AFCCAICGQTFDDEERLLAHQKKH 565



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 32/120 (26%), Positives = 50/120 (41%), Gaps = 14/120 (11%)

Query: 863 KEEGGKPERSSSPASALTPEG-EATSVTLVEELSLQEAMRKEPGESS-----------SR 910
           K   G  + +  P S   P G + ++      + L+ A    PG              S 
Sbjct: 315 KRSEGSAQAAPGPGSPQLPAGPQESAAEPTPAVPLKPAQEPPPGAPPEHPQDPIEAPPSL 374

Query: 911 KACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAHHQVQPFA 970
            +C+ CG++F  +  L  HQ+ H  E P FTC  C + F ++  L  H  + H   +PFA
Sbjct: 375 YSCDDCGRSFRLERFLRAHQRQHTGERP-FTCAECGKNFGKKTHLVAHSRV-HSGERPFA 432



 Score = 39.3 bits (90), Expect = 0.019
 Identities = 21/69 (30%), Positives = 27/69 (39%)

Query: 367 EKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREK 426
           + PG  H+C  C + F    AL +H R      P  C  CG RF     L +H   H   
Sbjct: 51  QAPGRAHRCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALHRQVHAAA 110

Query: 427 YPHVQMNPH 435
            P +    H
Sbjct: 111 TPDLGFACH 119



 Score = 39.3 bits (90), Expect = 0.019
 Identities = 26/85 (30%), Positives = 36/85 (42%), Gaps = 6/85 (7%)

Query: 630 PNQCVICLRVLSCPRALRLHYGQHGGERP---FKCKVCGRAFSTRGNLRAHFVGHKASPA 686
           P  C  C R       L LH   H    P   F C +CG++F     L  H   H A   
Sbjct: 84  PLPCPECGRRFRHAPFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSA--- 140

Query: 687 ARAQNSCPICQKKFTNAVTLQQHVR 711
           A+   +CP C+++F     L+ H+R
Sbjct: 141 AKRPIACPKCERRFWRRKQLRAHLR 165



 Score = 38.9 bits (89), Expect = 0.025
 Identities = 29/103 (28%), Positives = 39/103 (37%), Gaps = 1/103 (0%)

Query: 617 TSAPAPSSSASSGPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRA 676
           TS     + A    ++C  C R      AL LH  +     P  C  CGR F     L  
Sbjct: 43  TSVAQSGAQAPGRAHRCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLAL 102

Query: 677 HFVGHKASPAARAQNSCPICQKKFTNAVTLQQHVRMHLGGQIP 719
           H   H A+       +C +C + F   V L  H+R H   + P
Sbjct: 103 HRQVH-AAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRP 144



 Score = 37.0 bits (84), Expect = 0.093
 Identities = 17/52 (32%), Positives = 23/52 (44%)

Query: 912 ACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAH 963
           AC +CGQ+F    AL  H + H        C  C + F  R  L+ H+   H
Sbjct: 117 ACHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWRRKQLRAHLRRCH 168



 Score = 36.2 bits (82), Expect = 0.16
 Identities = 25/85 (29%), Positives = 28/85 (32%), Gaps = 31/85 (36%)

Query: 367 EKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCN---------------------- 404
           EKP   + C  C K F   S L  H R HTGERPY C                       
Sbjct: 484 EKP---YVCPDCGKAFSQKSNLVSHRRIHTGERPYACPDCDRSFSQKSNLITHRKSHIRD 540

Query: 405 ------VCGNRFTTRGNLKVHFHRH 423
                 +CG  F     L  H  +H
Sbjct: 541 GAFCCAICGQTFDDEERLLAHQKKH 565



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 2/58 (3%)

Query: 913 CEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAHHQVQPFA 970
           C  CG+AF  +  L  H++ H  E P + C  C + F +++ L  H  + H   +P+A
Sbjct: 461 CPDCGKAFRHKPYLAAHRRIHTGEKP-YVCPDCGKAFSQKSNLVSHRRI-HTGERPYA 516



 Score = 33.9 bits (76), Expect = 0.79
 Identities = 16/47 (34%), Positives = 25/47 (53%), Gaps = 1/47 (2%)

Query: 912 ACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKH 958
           AC  C ++F  ++ L  H+K+H ++G  F C  C Q F +   L  H
Sbjct: 516 ACPDCDRSFSQKSNLITHRKSHIRDG-AFCCAICGQTFDDEERLLAH 561



 Score = 33.1 bits (74), Expect = 1.3
 Identities = 22/77 (28%), Positives = 31/77 (40%), Gaps = 11/77 (14%)

Query: 913 CEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLL----------A 962
           C  CG+ F ++  L  H++ H  E P + C  C + F  +  L  H  +          A
Sbjct: 266 CPECGKRFTNKPYLTSHRRIHTGEKP-YPCKECGRRFRHKPNLLSHSKIHKRSEGSAQAA 324

Query: 963 HHQVQPFAPHGPQNIAA 979
                P  P GPQ  AA
Sbjct: 325 PGPGSPQLPAGPQESAA 341


>gi|153792647 replication initiator 1 isoform 3 [Homo sapiens]
          Length = 624

 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 101/429 (23%), Positives = 149/429 (34%), Gaps = 64/429 (14%)

Query: 294 RSHKPTPAPSPALPGSTDQLIASPHLAFPSTTGLLAAQCLGAARGLEATASPGLLKPKNG 353
           R H P P   P + G+  +       +F     L+A + +  A  LE  A+  L      
Sbjct: 223 RCHPPAPEARPFICGNCGR-------SFAQWDQLVAHKRVHVAEALEEAAAKAL------ 269

Query: 354 SGELSYGEVMGPLEKPGGR-----HKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGN 408
            G    G       +PGG       +C  C K F     L  H R HTGERP++C  CG 
Sbjct: 270 -GPRPRGRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPNLIAHRRVHTGERPHQCPECGK 328

Query: 409 RFTTRGNLKVHFHRHREKYPHVQMNPHPVPEHLDYVITSSGLPYGMSVPPEKAEEEA-AT 467
           RFT +  L  H   H  + P+          H   +++ S +        +++E  A A 
Sbjct: 329 RFTNKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIH-------KRSEGSAQAA 381

Query: 468 PGGGVERKPLVASTTALSATESLTLLSTSAGTATAPGLPAFNKFVLMKAVEPKNKADENT 527
           PG G  + P     +A   T ++ L          PG P            P++  D   
Sbjct: 382 PGPGSPQLPAGPQESAAEPTPAVPL---KPAQEPPPGAP------------PEHPQDPIE 426

Query: 528 PPGSEGSAISGVAESSTATRMQLSKLVTSLPSWALLTNHFKSTGSFPFPYVLEPLGASPS 587
            P S  S              +L +         L  +  + TG  PF       G +  
Sbjct: 427 APPSLYSC------DDCGRSFRLERF--------LRAHQRQHTGERPF--TCAECGKNFG 470

Query: 588 ETSKL--QQLVEKIDRQGAVAVTSAASGAPTTSAPAPSSSASSGPNQCVICLRVLSCPRA 645
           + + L     V   +R  A           +  A      A   P  C  C +       
Sbjct: 471 KKTHLVAHSRVHSGERPFACEECGRRFSQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPY 530

Query: 646 LRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARAQNSCPICQKKFTNAVT 705
           L  H   H GE+P+ C  CG+AFS + NL    V H+         +CP C + F+    
Sbjct: 531 LAAHRRIHTGEKPYVCPDCGKAFSQKSNL----VSHRRIHTGERPYACPDCDRSFSQKSN 586

Query: 706 LQQHVRMHL 714
           L  H + H+
Sbjct: 587 LITHRKSHI 595



 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 86/381 (22%), Positives = 136/381 (35%), Gaps = 56/381 (14%)

Query: 591 KLQQLVEKIDRQGAVAVTSAASGAPTTSAPAPSSSASSGPNQCVICLRVLSCPRALRLHY 650
           K   + E ++   A A+     G P  +AP P   A   P QC  C +       L  H 
Sbjct: 253 KRVHVAEALEEAAAKALGPRPRGRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPNLIAHR 312

Query: 651 GQHGGERPFKCKVCGRAFSTRGNLRAH---FVGHKASPAARAQNSCPICQKKFTNAVTLQ 707
             H GERP +C  CG+ F+ +  L +H     G K  P       C  C ++F +   L 
Sbjct: 313 RVHTGERPHQCPECGKRFTNKPYLTSHRRIHTGEKPYP-------CKECGRRFRHKPNLL 365

Query: 708 QHVRMHLGGQIPNGGTALPEGGGAAQENGSEQSTVSGAGSFPQQQSQQPSPEEELSEEEE 767
            H ++H   +            G+AQ      S    AG  PQ+ + +P+P   L   +E
Sbjct: 366 SHSKIHKRSE------------GSAQAAPGPGSPQLPAG--PQESAAEPTPAVPLKPAQE 411

Query: 768 EEDEEEEEDVTDEDSLAGRGSESGGEKAISVRGDSEEASGAEEEVGTVA-AAATAGKEMD 826
                  E   D    A     S  +   S R +    +   +  G      A  GK   
Sbjct: 412 PPPGAPPEHPQDPIE-APPSLYSCDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFG 470

Query: 827 SNEKTTQQSSLPPPPPPDSLDQ-PQPMEQGSSGVLGGKEEGGKPERSSSPASALTPEGEA 885
                   S +     P + ++  +   QGS   L        P+R       + P+   
Sbjct: 471 KKTHLVAHSRVHSGERPFACEECGRRFSQGSH--LAAHRRDHAPDRPF-----VCPD--- 520

Query: 886 TSVTLVEELSLQEAMRKEPGESSSRK--------ACEVCGQAFPSQAALEEHQKTHPKEG 937
                       +A R +P  ++ R+         C  CG+AF  ++ L  H++ H  E 
Sbjct: 521 ----------CGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAFSQKSNLVSHRRIHTGER 570

Query: 938 PLFTCVFCRQGFLERATLKKH 958
           P + C  C + F +++ L  H
Sbjct: 571 P-YACPDCDRSFSQKSNLITH 590



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 82/358 (22%), Positives = 116/358 (32%), Gaps = 65/358 (18%)

Query: 375 CRFCAKVFGSDSALQIHLRSHTG-ERPYKCNVCGNRFTTRGNLKVHFHRHREKYPHVQMN 433
           C  C + F    AL +HLR+H+  +RP  C  C  RF  R  L+ H  R           
Sbjct: 175 CHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWRRKQLRAHLRRCHP-------- 226

Query: 434 PHPVPEHLDYVITSSGLPYGM--------SVPPEKAEEEAATPGGGVERKPLVASTTALS 485
             P PE   ++  + G  +           V   +A EEAA    G   +          
Sbjct: 227 --PAPEARPFICGNCGRSFAQWDQLVAHKRVHVAEALEEAAAKALGPRPR---------- 274

Query: 486 ATESLTLLSTSAGTATAPGLPAFNKFVLMKAVEPKNKADENTPPGSEGSAISGVAESSTA 545
                      A TA  PG  A ++         + +   N         +       T 
Sbjct: 275 --------GRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPN---------LIAHRRVHTG 317

Query: 546 TR----MQLSKLVTSLPSWALLTNHFK-STGSFPFPYVLEPLGASPSETSKLQQLVEKID 600
            R     +  K  T+ P    LT+H +  TG  P+P   +  G        L    +   
Sbjct: 318 ERPHQCPECGKRFTNKP---YLTSHRRIHTGEKPYP--CKECGRRFRHKPNLLSHSKIHK 372

Query: 601 RQGAVAVTSAASGAPTTSAPAPSSSASSGPNQCVICLRVLSCPRALRLHYGQHGGERP-- 658
           R    A  +   G+P    PA    +++ P   V        P      + Q   E P  
Sbjct: 373 RSEGSAQAAPGPGSP--QLPAGPQESAAEPTPAVPLKPAQEPPPGAPPEHPQDPIEAPPS 430

Query: 659 -FKCKVCGRAFSTRGNLRAHFVGHKASPAARAQNSCPICQKKFTNAVTLQQHVRMHLG 715
            + C  CGR+F     LRAH   H          +C  C K F     L  H R+H G
Sbjct: 431 LYSCDDCGRSFRLERFLRAHQRQH----TGERPFTCAECGKNFGKKTHLVAHSRVHSG 484



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 4/84 (4%)

Query: 630 PNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARA 689
           P  C  C +  S    L  H   H GERP+ C  C R+FS + NL    + H+ S     
Sbjct: 543 PYVCPDCGKAFSQKSNLVSHRRIHTGERPYACPDCDRSFSQKSNL----ITHRKSHIRDG 598

Query: 690 QNSCPICQKKFTNAVTLQQHVRMH 713
              C IC + F +   L  H + H
Sbjct: 599 AFCCAICGQTFDDEERLLAHQKKH 622



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 32/120 (26%), Positives = 50/120 (41%), Gaps = 14/120 (11%)

Query: 863 KEEGGKPERSSSPASALTPEG-EATSVTLVEELSLQEAMRKEPGESS-----------SR 910
           K   G  + +  P S   P G + ++      + L+ A    PG              S 
Sbjct: 372 KRSEGSAQAAPGPGSPQLPAGPQESAAEPTPAVPLKPAQEPPPGAPPEHPQDPIEAPPSL 431

Query: 911 KACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAHHQVQPFA 970
            +C+ CG++F  +  L  HQ+ H  E P FTC  C + F ++  L  H  + H   +PFA
Sbjct: 432 YSCDDCGRSFRLERFLRAHQRQHTGERP-FTCAECGKNFGKKTHLVAHSRV-HSGERPFA 489



 Score = 39.3 bits (90), Expect = 0.019
 Identities = 21/69 (30%), Positives = 27/69 (39%)

Query: 367 EKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREK 426
           + PG  H+C  C + F    AL +H R      P  C  CG RF     L +H   H   
Sbjct: 108 QAPGRAHRCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALHRQVHAAA 167

Query: 427 YPHVQMNPH 435
            P +    H
Sbjct: 168 TPDLGFACH 176



 Score = 39.3 bits (90), Expect = 0.019
 Identities = 26/85 (30%), Positives = 36/85 (42%), Gaps = 6/85 (7%)

Query: 630 PNQCVICLRVLSCPRALRLHYGQHGGERP---FKCKVCGRAFSTRGNLRAHFVGHKASPA 686
           P  C  C R       L LH   H    P   F C +CG++F     L  H   H A   
Sbjct: 141 PLPCPECGRRFRHAPFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSA--- 197

Query: 687 ARAQNSCPICQKKFTNAVTLQQHVR 711
           A+   +CP C+++F     L+ H+R
Sbjct: 198 AKRPIACPKCERRFWRRKQLRAHLR 222



 Score = 38.9 bits (89), Expect = 0.025
 Identities = 29/103 (28%), Positives = 39/103 (37%), Gaps = 1/103 (0%)

Query: 617 TSAPAPSSSASSGPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRA 676
           TS     + A    ++C  C R      AL LH  +     P  C  CGR F     L  
Sbjct: 100 TSVAQSGAQAPGRAHRCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLAL 159

Query: 677 HFVGHKASPAARAQNSCPICQKKFTNAVTLQQHVRMHLGGQIP 719
           H   H A+       +C +C + F   V L  H+R H   + P
Sbjct: 160 HRQVH-AAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRP 201



 Score = 37.0 bits (84), Expect = 0.093
 Identities = 17/52 (32%), Positives = 23/52 (44%)

Query: 912 ACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAH 963
           AC +CGQ+F    AL  H + H        C  C + F  R  L+ H+   H
Sbjct: 174 ACHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWRRKQLRAHLRRCH 225



 Score = 36.2 bits (82), Expect = 0.16
 Identities = 25/85 (29%), Positives = 28/85 (32%), Gaps = 31/85 (36%)

Query: 367 EKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCN---------------------- 404
           EKP   + C  C K F   S L  H R HTGERPY C                       
Sbjct: 541 EKP---YVCPDCGKAFSQKSNLVSHRRIHTGERPYACPDCDRSFSQKSNLITHRKSHIRD 597

Query: 405 ------VCGNRFTTRGNLKVHFHRH 423
                 +CG  F     L  H  +H
Sbjct: 598 GAFCCAICGQTFDDEERLLAHQKKH 622



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 2/58 (3%)

Query: 913 CEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAHHQVQPFA 970
           C  CG+AF  +  L  H++ H  E P + C  C + F +++ L  H  + H   +P+A
Sbjct: 518 CPDCGKAFRHKPYLAAHRRIHTGEKP-YVCPDCGKAFSQKSNLVSHRRI-HTGERPYA 573



 Score = 33.9 bits (76), Expect = 0.79
 Identities = 16/47 (34%), Positives = 25/47 (53%), Gaps = 1/47 (2%)

Query: 912 ACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKH 958
           AC  C ++F  ++ L  H+K+H ++G  F C  C Q F +   L  H
Sbjct: 573 ACPDCDRSFSQKSNLITHRKSHIRDG-AFCCAICGQTFDDEERLLAH 618



 Score = 33.1 bits (74), Expect = 1.3
 Identities = 22/77 (28%), Positives = 31/77 (40%), Gaps = 11/77 (14%)

Query: 913 CEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLL----------A 962
           C  CG+ F ++  L  H++ H  E P + C  C + F  +  L  H  +          A
Sbjct: 323 CPECGKRFTNKPYLTSHRRIHTGEKP-YPCKECGRRFRHKPNLLSHSKIHKRSEGSAQAA 381

Query: 963 HHQVQPFAPHGPQNIAA 979
                P  P GPQ  AA
Sbjct: 382 PGPGSPQLPAGPQESAA 398


>gi|153791994 replication initiator 1 isoform 1 [Homo sapiens]
          Length = 567

 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 101/429 (23%), Positives = 149/429 (34%), Gaps = 64/429 (14%)

Query: 294 RSHKPTPAPSPALPGSTDQLIASPHLAFPSTTGLLAAQCLGAARGLEATASPGLLKPKNG 353
           R H P P   P + G+  +       +F     L+A + +  A  LE  A+  L      
Sbjct: 166 RCHPPAPEARPFICGNCGR-------SFAQWDQLVAHKRVHVAEALEEAAAKAL------ 212

Query: 354 SGELSYGEVMGPLEKPGGR-----HKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGN 408
            G    G       +PGG       +C  C K F     L  H R HTGERP++C  CG 
Sbjct: 213 -GPRPRGRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPNLIAHRRVHTGERPHQCPECGK 271

Query: 409 RFTTRGNLKVHFHRHREKYPHVQMNPHPVPEHLDYVITSSGLPYGMSVPPEKAEEEA-AT 467
           RFT +  L  H   H  + P+          H   +++ S +        +++E  A A 
Sbjct: 272 RFTNKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIH-------KRSEGSAQAA 324

Query: 468 PGGGVERKPLVASTTALSATESLTLLSTSAGTATAPGLPAFNKFVLMKAVEPKNKADENT 527
           PG G  + P     +A   T ++ L          PG P            P++  D   
Sbjct: 325 PGPGSPQLPAGPQESAAEPTPAVPL---KPAQEPPPGAP------------PEHPQDPIE 369

Query: 528 PPGSEGSAISGVAESSTATRMQLSKLVTSLPSWALLTNHFKSTGSFPFPYVLEPLGASPS 587
            P S  S              +L +         L  +  + TG  PF       G +  
Sbjct: 370 APPSLYSC------DDCGRSFRLERF--------LRAHQRQHTGERPF--TCAECGKNFG 413

Query: 588 ETSKL--QQLVEKIDRQGAVAVTSAASGAPTTSAPAPSSSASSGPNQCVICLRVLSCPRA 645
           + + L     V   +R  A           +  A      A   P  C  C +       
Sbjct: 414 KKTHLVAHSRVHSGERPFACEECGRRFSQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPY 473

Query: 646 LRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARAQNSCPICQKKFTNAVT 705
           L  H   H GE+P+ C  CG+AFS + NL    V H+         +CP C + F+    
Sbjct: 474 LAAHRRIHTGEKPYVCPDCGKAFSQKSNL----VSHRRIHTGERPYACPDCDRSFSQKSN 529

Query: 706 LQQHVRMHL 714
           L  H + H+
Sbjct: 530 LITHRKSHI 538



 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 86/381 (22%), Positives = 136/381 (35%), Gaps = 56/381 (14%)

Query: 591 KLQQLVEKIDRQGAVAVTSAASGAPTTSAPAPSSSASSGPNQCVICLRVLSCPRALRLHY 650
           K   + E ++   A A+     G P  +AP P   A   P QC  C +       L  H 
Sbjct: 196 KRVHVAEALEEAAAKALGPRPRGRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPNLIAHR 255

Query: 651 GQHGGERPFKCKVCGRAFSTRGNLRAH---FVGHKASPAARAQNSCPICQKKFTNAVTLQ 707
             H GERP +C  CG+ F+ +  L +H     G K  P       C  C ++F +   L 
Sbjct: 256 RVHTGERPHQCPECGKRFTNKPYLTSHRRIHTGEKPYP-------CKECGRRFRHKPNLL 308

Query: 708 QHVRMHLGGQIPNGGTALPEGGGAAQENGSEQSTVSGAGSFPQQQSQQPSPEEELSEEEE 767
            H ++H   +            G+AQ      S    AG  PQ+ + +P+P   L   +E
Sbjct: 309 SHSKIHKRSE------------GSAQAAPGPGSPQLPAG--PQESAAEPTPAVPLKPAQE 354

Query: 768 EEDEEEEEDVTDEDSLAGRGSESGGEKAISVRGDSEEASGAEEEVGTVA-AAATAGKEMD 826
                  E   D    A     S  +   S R +    +   +  G      A  GK   
Sbjct: 355 PPPGAPPEHPQDPIE-APPSLYSCDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFG 413

Query: 827 SNEKTTQQSSLPPPPPPDSLDQ-PQPMEQGSSGVLGGKEEGGKPERSSSPASALTPEGEA 885
                   S +     P + ++  +   QGS   L        P+R       + P+   
Sbjct: 414 KKTHLVAHSRVHSGERPFACEECGRRFSQGSH--LAAHRRDHAPDRPF-----VCPD--- 463

Query: 886 TSVTLVEELSLQEAMRKEPGESSSRK--------ACEVCGQAFPSQAALEEHQKTHPKEG 937
                       +A R +P  ++ R+         C  CG+AF  ++ L  H++ H  E 
Sbjct: 464 ----------CGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAFSQKSNLVSHRRIHTGER 513

Query: 938 PLFTCVFCRQGFLERATLKKH 958
           P + C  C + F +++ L  H
Sbjct: 514 P-YACPDCDRSFSQKSNLITH 533



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 82/358 (22%), Positives = 116/358 (32%), Gaps = 65/358 (18%)

Query: 375 CRFCAKVFGSDSALQIHLRSHTG-ERPYKCNVCGNRFTTRGNLKVHFHRHREKYPHVQMN 433
           C  C + F    AL +HLR+H+  +RP  C  C  RF  R  L+ H  R           
Sbjct: 118 CHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWRRKQLRAHLRRCHP-------- 169

Query: 434 PHPVPEHLDYVITSSGLPYGM--------SVPPEKAEEEAATPGGGVERKPLVASTTALS 485
             P PE   ++  + G  +           V   +A EEAA    G   +          
Sbjct: 170 --PAPEARPFICGNCGRSFAQWDQLVAHKRVHVAEALEEAAAKALGPRPR---------- 217

Query: 486 ATESLTLLSTSAGTATAPGLPAFNKFVLMKAVEPKNKADENTPPGSEGSAISGVAESSTA 545
                      A TA  PG  A ++         + +   N         +       T 
Sbjct: 218 --------GRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPN---------LIAHRRVHTG 260

Query: 546 TR----MQLSKLVTSLPSWALLTNHFK-STGSFPFPYVLEPLGASPSETSKLQQLVEKID 600
            R     +  K  T+ P    LT+H +  TG  P+P   +  G        L    +   
Sbjct: 261 ERPHQCPECGKRFTNKP---YLTSHRRIHTGEKPYP--CKECGRRFRHKPNLLSHSKIHK 315

Query: 601 RQGAVAVTSAASGAPTTSAPAPSSSASSGPNQCVICLRVLSCPRALRLHYGQHGGERP-- 658
           R    A  +   G+P    PA    +++ P   V        P      + Q   E P  
Sbjct: 316 RSEGSAQAAPGPGSP--QLPAGPQESAAEPTPAVPLKPAQEPPPGAPPEHPQDPIEAPPS 373

Query: 659 -FKCKVCGRAFSTRGNLRAHFVGHKASPAARAQNSCPICQKKFTNAVTLQQHVRMHLG 715
            + C  CGR+F     LRAH   H          +C  C K F     L  H R+H G
Sbjct: 374 LYSCDDCGRSFRLERFLRAHQRQH----TGERPFTCAECGKNFGKKTHLVAHSRVHSG 427



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 4/84 (4%)

Query: 630 PNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARA 689
           P  C  C +  S    L  H   H GERP+ C  C R+FS + NL    + H+ S     
Sbjct: 486 PYVCPDCGKAFSQKSNLVSHRRIHTGERPYACPDCDRSFSQKSNL----ITHRKSHIRDG 541

Query: 690 QNSCPICQKKFTNAVTLQQHVRMH 713
              C IC + F +   L  H + H
Sbjct: 542 AFCCAICGQTFDDEERLLAHQKKH 565



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 32/120 (26%), Positives = 50/120 (41%), Gaps = 14/120 (11%)

Query: 863 KEEGGKPERSSSPASALTPEG-EATSVTLVEELSLQEAMRKEPGESS-----------SR 910
           K   G  + +  P S   P G + ++      + L+ A    PG              S 
Sbjct: 315 KRSEGSAQAAPGPGSPQLPAGPQESAAEPTPAVPLKPAQEPPPGAPPEHPQDPIEAPPSL 374

Query: 911 KACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAHHQVQPFA 970
            +C+ CG++F  +  L  HQ+ H  E P FTC  C + F ++  L  H  + H   +PFA
Sbjct: 375 YSCDDCGRSFRLERFLRAHQRQHTGERP-FTCAECGKNFGKKTHLVAHSRV-HSGERPFA 432



 Score = 39.3 bits (90), Expect = 0.019
 Identities = 21/69 (30%), Positives = 27/69 (39%)

Query: 367 EKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREK 426
           + PG  H+C  C + F    AL +H R      P  C  CG RF     L +H   H   
Sbjct: 51  QAPGRAHRCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALHRQVHAAA 110

Query: 427 YPHVQMNPH 435
            P +    H
Sbjct: 111 TPDLGFACH 119



 Score = 39.3 bits (90), Expect = 0.019
 Identities = 26/85 (30%), Positives = 36/85 (42%), Gaps = 6/85 (7%)

Query: 630 PNQCVICLRVLSCPRALRLHYGQHGGERP---FKCKVCGRAFSTRGNLRAHFVGHKASPA 686
           P  C  C R       L LH   H    P   F C +CG++F     L  H   H A   
Sbjct: 84  PLPCPECGRRFRHAPFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSA--- 140

Query: 687 ARAQNSCPICQKKFTNAVTLQQHVR 711
           A+   +CP C+++F     L+ H+R
Sbjct: 141 AKRPIACPKCERRFWRRKQLRAHLR 165



 Score = 38.9 bits (89), Expect = 0.025
 Identities = 29/103 (28%), Positives = 39/103 (37%), Gaps = 1/103 (0%)

Query: 617 TSAPAPSSSASSGPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRA 676
           TS     + A    ++C  C R      AL LH  +     P  C  CGR F     L  
Sbjct: 43  TSVAQSGAQAPGRAHRCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLAL 102

Query: 677 HFVGHKASPAARAQNSCPICQKKFTNAVTLQQHVRMHLGGQIP 719
           H   H A+       +C +C + F   V L  H+R H   + P
Sbjct: 103 HRQVH-AAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRP 144



 Score = 37.0 bits (84), Expect = 0.093
 Identities = 17/52 (32%), Positives = 23/52 (44%)

Query: 912 ACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAH 963
           AC +CGQ+F    AL  H + H        C  C + F  R  L+ H+   H
Sbjct: 117 ACHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWRRKQLRAHLRRCH 168



 Score = 36.2 bits (82), Expect = 0.16
 Identities = 25/85 (29%), Positives = 28/85 (32%), Gaps = 31/85 (36%)

Query: 367 EKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCN---------------------- 404
           EKP   + C  C K F   S L  H R HTGERPY C                       
Sbjct: 484 EKP---YVCPDCGKAFSQKSNLVSHRRIHTGERPYACPDCDRSFSQKSNLITHRKSHIRD 540

Query: 405 ------VCGNRFTTRGNLKVHFHRH 423
                 +CG  F     L  H  +H
Sbjct: 541 GAFCCAICGQTFDDEERLLAHQKKH 565



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 2/58 (3%)

Query: 913 CEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAHHQVQPFA 970
           C  CG+AF  +  L  H++ H  E P + C  C + F +++ L  H  + H   +P+A
Sbjct: 461 CPDCGKAFRHKPYLAAHRRIHTGEKP-YVCPDCGKAFSQKSNLVSHRRI-HTGERPYA 516



 Score = 33.9 bits (76), Expect = 0.79
 Identities = 16/47 (34%), Positives = 25/47 (53%), Gaps = 1/47 (2%)

Query: 912 ACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKH 958
           AC  C ++F  ++ L  H+K+H ++G  F C  C Q F +   L  H
Sbjct: 516 ACPDCDRSFSQKSNLITHRKSHIRDG-AFCCAICGQTFDDEERLLAH 561



 Score = 33.1 bits (74), Expect = 1.3
 Identities = 22/77 (28%), Positives = 31/77 (40%), Gaps = 11/77 (14%)

Query: 913 CEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLL----------A 962
           C  CG+ F ++  L  H++ H  E P + C  C + F  +  L  H  +          A
Sbjct: 266 CPECGKRFTNKPYLTSHRRIHTGEKP-YPCKECGRRFRHKPNLLSHSKIHKRSEGSAQAA 324

Query: 963 HHQVQPFAPHGPQNIAA 979
                P  P GPQ  AA
Sbjct: 325 PGPGSPQLPAGPQESAA 341


>gi|170932550 FLT3-interacting zinc finger 1 [Homo sapiens]
          Length = 496

 Score = 79.0 bits (193), Expect = 2e-14
 Identities = 104/416 (25%), Positives = 139/416 (33%), Gaps = 58/416 (13%)

Query: 302 PSPALPGSTDQLIASPHLAFPSTTGLLAAQCLGAARGLEATASPGLLKPKNGSGELSYGE 361
           PSP  PG        P L+ P +       C     G  A    G      G G     E
Sbjct: 135 PSPLQPGP-----GLPALSAPCSVCCNVGPC-SVCGGSGAGGGEGPEGAGAGLGSWGLAE 188

Query: 362 VMGPLEKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFH 421
                        C  CA+ F     L  H  +HT  +P+KC  C   F     L+ H  
Sbjct: 189 AAAAAAASLPPFACGACARRFDHGRELAAHWAAHTDVKPFKCPRCERDFNAPALLERH-- 246

Query: 422 RHREKYPHVQMNPHPVPEHLDYVITSSGLPYGMSVPPEKAEEEAATPGGGVERKPLVAST 481
               K  H    P   P        +     G    PE A E  A   G     PL    
Sbjct: 247 ----KLTHDLQGPGAPP--------AQAWAAGPGAGPETAGEGTAAEAGDA---PL---- 287

Query: 482 TALSATESLTLLSTSAGTATAPGLPAFNKFVLMKAVEPKNKADENTPPGSEGSAISGVAE 541
               A++   LL  + G     G+P     +      P+         G E  A +  AE
Sbjct: 288 ----ASDRRLLLGPAGG-----GVPKLGGLL------PEG--------GGEAPAPAAAAE 324

Query: 542 SSTATRMQLSKLVTSLPSWALLTNHFKSTGSFPFPYVLEPLGASPSETSKLQQ--LVEKI 599
            S  T  Q     T   S A L +H ++  S P  Y     GA  +  + L++   V   
Sbjct: 325 PSEDTLYQCD-CGTFFASAAALASHLEAH-SGPATYGCGHCGALYAALAALEEHRRVSHG 382

Query: 600 DRQGAVAVTSAASGAPTTSAPAPSSSASSGPNQCVICLRVLSCPRALRLHYGQHGGERPF 659
           +  G  A T+A    P +  P   S        C  C ++   PR L  H   H GE+PF
Sbjct: 383 EGGGEEAATAAREREPASGEPPSGSGRGKKIFGCSECEKLFRSPRDLERHVLVHTGEKPF 442

Query: 660 KCKVCGRAFSTRGNLRAHFVGHKASPAARAQNSCPICQKKFTNAVTLQQHVRMHLG 715
            C  CG+ F     L+ H + H           C IC K F     L +H+++H G
Sbjct: 443 PCLECGKFFRHECYLKRHRLLH----GTERPFPCHICGKGFITLSNLSRHLKLHRG 494



 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 90/377 (23%), Positives = 129/377 (34%), Gaps = 89/377 (23%)

Query: 610 AASGAPTTSAPAPSSSASSGPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFS 669
           A  G+   +  A +++AS  P  C  C R     R L  H+  H   +PFKC  C R F+
Sbjct: 179 AGLGSWGLAEAAAAAAASLPPFACGACARRFDHGRELAAHWAAHTDVKPFKCPRCERDFN 238

Query: 670 TRGNLRAHFVGHK----ASPAARAQNSCPICQKKFTNAVT--------LQQHVRMHLG-- 715
               L  H + H      +P A+A  + P    +     T        L    R+ LG  
Sbjct: 239 APALLERHKLTHDLQGPGAPPAQAWAAGPGAGPETAGEGTAAEAGDAPLASDRRLLLGPA 298

Query: 716 -GQIPNGGTALPEGGGAAQENGSEQSTVSGAGSFPQQQSQQPSPEEELSEEEEEEDEEEE 774
            G +P  G  LPEGGG                       + P+P    +  E  ED   +
Sbjct: 299 GGGVPKLGGLLPEGGG-----------------------EAPAPA---AAAEPSEDTLYQ 332

Query: 775 EDVTDEDSLAGRGSESGGEKAISVRGDSEEASGAEEEVGTVAAAATAGKEMDSNEKTTQQ 834
            D        G    S    A  +   S  A+      G + AA  A             
Sbjct: 333 CD-------CGTFFASAAALASHLEAHSGPATYGCGHCGALYAALAA------------- 372

Query: 835 SSLPPPPPPDSLDQPQPMEQGSSGVLGGKEEGGKPERSSSPASALTPEGEATSVTLV--- 891
                      L++ + +  G     GG EE     R   PAS   P G      +    
Sbjct: 373 -----------LEEHRRVSHGE----GGGEEAATAAREREPASGEPPSGSGRGKKIFGCS 417

Query: 892 --EEL-----SLQEAMRKEPGESSSRKACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVF 944
             E+L      L+  +    GE      C  CG+ F  +  L+ H+  H  E P F C  
Sbjct: 418 ECEKLFRSPRDLERHVLVHTGEKPF--PCLECGKFFRHECYLKRHRLLHGTERP-FPCHI 474

Query: 945 CRQGFLERATLKKHMLL 961
           C +GF+  + L +H+ L
Sbjct: 475 CGKGFITLSNLSRHLKL 491



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 105/462 (22%), Positives = 161/462 (34%), Gaps = 72/462 (15%)

Query: 298 PTPAPSPALPGSTDQLIASPHLAFPSTTGLLAAQCLGAARGLEA--TASPGLLKPKNGSG 355
           P P P+PA P +     A+P + F  +    + +     R   A  TA      P+ G G
Sbjct: 5   PAPTPAPAPPAA-----AAPRVPFHCSECGKSFRYRSDLRRHFARHTALKPHACPRCGKG 59

Query: 356 ELSYGEVMGPLEKPGGR--HKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTR 413
                 +   L    G   ++C  C K F   + L  H   HTGE+PY C VC  RF++R
Sbjct: 60  FKHSFNLANHLRSHTGERPYRCSACPKGFRDSTGLLHHQVVHTGEKPYCCLVCELRFSSR 119

Query: 414 GNLKVHFHRHREKYPHVQMNPHPVPEHLDYVITSSGLPYGMSVPPEKAEEEAATPGG-GV 472
            +L  H  R      H  + P P+         S+      +V P      +   GG G 
Sbjct: 120 SSLGRHLKRQ-----HRGVLPSPLQPGPGLPALSAPCSVCCNVGPCSVCGGSGAGGGEGP 174

Query: 473 ERKPLVASTTALSATESLTLLSTSAGTATAPGLPAFNKFVLMKAVEPKNKADENTPPGSE 532
           E       +  L+           A  A A  LP F      +      + D      + 
Sbjct: 175 EGAGAGLGSWGLA----------EAAAAAAASLPPFACGACAR------RFDHGRELAAH 218

Query: 533 GSAISGVAESSTATRMQLSKLVTSLPSWALLTNHFKSTGSFPFPYVLEPLGASPSETSKL 592
            +A + V +     R +      +L     LT+  +  G+ P        GA P ET+  
Sbjct: 219 WAAHTDV-KPFKCPRCERDFNAPALLERHKLTHDLQGPGAPPAQAWAAGPGAGP-ETAGE 276

Query: 593 QQLVEKIDRQGA----VAVTSAASGAPTT-------SAPAPSSSASSGPNQCVI----CL 637
               E  D   A    + +  A  G P            AP+ +A++ P++  +    C 
Sbjct: 277 GTAAEAGDAPLASDRRLLLGPAGGGVPKLGGLLPEGGGEAPAPAAAAEPSEDTLYQCDCG 336

Query: 638 RVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAH-------FVGHKASPAARAQ 690
              +   AL  H   H G   + C  CG  ++    L  H         G +A+ AAR +
Sbjct: 337 TFFASAAALASHLEAHSGPATYGCGHCGALYAALAALEEHRRVSHGEGGGEEAATAARER 396

Query: 691 N-----------------SCPICQKKFTNAVTLQQHVRMHLG 715
                              C  C+K F +   L++HV +H G
Sbjct: 397 EPASGEPPSGSGRGKKIFGCSECEKLFRSPRDLERHVLVHTG 438



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 26/87 (29%), Positives = 36/87 (41%), Gaps = 3/87 (3%)

Query: 895 SLQEAMRKEPGESSSRKACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERAT 954
           +L   +R   GE   R  C  C + F     L  HQ  H  E P + C+ C   F  R++
Sbjct: 65  NLANHLRSHTGERPYR--CSACPKGFRDSTGLLHHQVVHTGEKP-YCCLVCELRFSSRSS 121

Query: 955 LKKHMLLAHHQVQPFAPHGPQNIAALS 981
           L +H+   H  V P        + ALS
Sbjct: 122 LGRHLKRQHRGVLPSPLQPGPGLPALS 148



 Score = 37.4 bits (85), Expect = 0.072
 Identities = 36/137 (26%), Positives = 51/137 (37%), Gaps = 21/137 (15%)

Query: 624 SSASSGPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGH-- 681
           S     P +C  C +       L  H   H GE+P+ C VC   FS+R +L  H      
Sbjct: 72  SHTGERPYRCSACPKGFRDSTGLLHHQVVHTGEKPYCCLVCELRFSSRSSLGRHLKRQHR 131

Query: 682 -------KASPAARAQNS-CPICQKKFTNAVTLQQHVRMHLGGQIPNGGTALPEGGGAAQ 733
                  +  P   A ++ C +C      +V          GG    GG   PEG GA  
Sbjct: 132 GVLPSPLQPGPGLPALSAPCSVCCNVGPCSV---------CGGSGAGGGEG-PEGAGAGL 181

Query: 734 EN-GSEQSTVSGAGSFP 749
            + G  ++  + A S P
Sbjct: 182 GSWGLAEAAAAAAASLP 198



 Score = 33.9 bits (76), Expect = 0.79
 Identities = 18/58 (31%), Positives = 28/58 (48%), Gaps = 2/58 (3%)

Query: 912 ACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAHHQVQPF 969
           AC  CG+ F     L  H ++H  E P + C  C +GF +   L  H ++ H   +P+
Sbjct: 52  ACPRCGKGFKHSFNLANHLRSHTGERP-YRCSACPKGFRDSTGLLHHQVV-HTGEKPY 107



 Score = 31.2 bits (69), Expect = 5.1
 Identities = 31/106 (29%), Positives = 44/106 (41%), Gaps = 18/106 (16%)

Query: 859 VLGGKEEGGKPERSSSPASALTPEGEATSVTLVEELSLQEAMRKEPGESSSRKACEVCGQ 918
           +L G   GG P+        L PEG   +           A   EP E +  + C+ CG 
Sbjct: 293 LLLGPAGGGVPK-----LGGLLPEGGGEAPA--------PAAAAEPSEDTLYQ-CD-CGT 337

Query: 919 AFPSQAALEEHQKTHPKEGP-LFTCVFCRQGFLERATLKKHMLLAH 963
            F S AAL  H + H   GP  + C  C   +   A L++H  ++H
Sbjct: 338 FFASAAALASHLEAH--SGPATYGCGHCGALYAALAALEEHRRVSH 381


>gi|189181750 human immunodeficiency virus type I enhancer binding
           protein 3 b [Homo sapiens]
          Length = 2405

 Score = 78.6 bits (192), Expect = 3e-14
 Identities = 116/429 (27%), Positives = 171/429 (39%), Gaps = 103/429 (24%)

Query: 205 RQVLLLGSLGQTVGAPASPSELPGTGTASSTK-PLLPLFSPIKPVQTSKTLASSSSSSSS 263
           R+ L  G   QT  + + P   PG+GTA++ + P   L +P +P     ++    S   +
Sbjct: 18  RKRLTKGEAIQTSVSSSVP--YPGSGTAATQESPAQELLAP-QPFPGPSSVLREGSQEKT 74

Query: 264 SSGAETPK----QAFFHLYHPLGSQHPFSAGGVGRSHKPTPA------PSPALPGSTDQL 313
               + PK    +A  H+     SQ P         H  TPA      P   L GST QL
Sbjct: 75  GQQQKPPKRPPIEASVHI-----SQLP--------QHPLTPAFMSPGKPEHLLEGSTWQL 121

Query: 314 I-----------ASPHL-----AFPSTTGLLAAQCL-GAARGLEATASPGLLKPKNGSGE 356
           +            +P L       PS   ++  + L G  +      S   LKP     E
Sbjct: 122 VDPMRPGPSGSFVAPGLHPQSQLLPSHASIIPPEDLPGVPKVFVPRPSQVSLKPT----E 177

Query: 357 LSYGEVMGPLEKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNL 416
            ++ +   P +KPG ++ C++C++     S LQ H+RSHTGERPY C  CG  F T+ NL
Sbjct: 178 EAHKKERKP-QKPG-KYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNL 235

Query: 417 KVH--FHRHR-----------EKYPH-VQMNPHPVPEHLDYVITSSGLPYGMSVPPEKAE 462
             H   H HR           E YPH ++M   P  E  +     S          +  E
Sbjct: 236 YKHRKSHAHRIKAGLASGMGGEMYPHGLEMERIPGEEFEEPTEGES---------TDSEE 286

Query: 463 EEAATPGGGVE-----RKPLVASTTALSATESLT----LLSTSAGTATAPGLPAF----- 508
           E +AT G   E     ++PL++S    S + S +     LS S+   +    P F     
Sbjct: 287 ETSATSGHPAELSPRPKQPLLSSGLYSSGSHSSSHERCSLSQSSTAQSLEDPPPFVEPSS 346

Query: 509 --------------NKFVLMKAVEPKNKADENT--PPGSEGSAISGVAESSTATRMQLSK 552
                          + + ++  E K   DE     PGS+GS  SG    S +   Q+S 
Sbjct: 347 EHPLSHKPEDTHTIKQKLALRLSERKKVIDEQAFLSPGSKGSTESGYFSRSESAEQQVSP 406

Query: 553 LVTSLPSWA 561
             T+  S+A
Sbjct: 407 PNTNAKSYA 415



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 20/49 (40%), Positives = 25/49 (51%)

Query: 633 CVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGH 681
           C  C R  + P  L+ H   H GERP+ C  CG +F T+ NL  H   H
Sbjct: 194 CQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSH 242



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 61/249 (24%), Positives = 86/249 (34%), Gaps = 41/249 (16%)

Query: 643  PRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARAQNSCPICQKKFTN 702
            P  L+ H   H   RP+ CK C  AF T+GNL  H      S             KK   
Sbjct: 1766 PSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHS-------------KKCQE 1812

Query: 703  AVTLQQHVRMHLGGQIPNGGTALPEGGGAAQENGSEQSTVSGAGSFPQQQSQQPSPEEEL 762
               L++                L    G + +   +     G+ +  + Q       +  
Sbjct: 1813 TGVLEE----------------LEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSD 1856

Query: 763  SEEEEEEDEEEEEDVTDEDSLAGRGSES---GGEKAISVRGDSEEASGAE-EEVGTVAAA 818
            S+ +E+EDE+EEE    +D L+   SE+   G   A+  R DS    G +  +       
Sbjct: 1857 SDLDEDEDEDEEE---SQDELSRPSSEAPPPGPPHAL--RADSSPILGPQPPDAPASGTE 1911

Query: 819  ATAGKEMDSNEKTTQQSSLPPPPPPDSLDQPQPMEQGSSGVLGGKEEGGKPERSSSPASA 878
            AT G  +   E+ T  S          L    P   GS     G     KP    SP   
Sbjct: 1912 ATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKP---VSPRRP 1968

Query: 879  LTPEGEATS 887
             +P  EA S
Sbjct: 1969 WSPSKEAGS 1977



 Score = 43.9 bits (102), Expect = 8e-04
 Identities = 20/49 (40%), Positives = 26/49 (53%)

Query: 371  GRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVH 419
            G++ C  C       S L+ H+R+HT  RPY C  C   F T+GNL  H
Sbjct: 1752 GKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKH 1800



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 40/136 (29%), Positives = 58/136 (42%), Gaps = 21/136 (15%)

Query: 760  EELSEEEEEEDEEEEEDVTDEDSLAGRGSESGGEKAISVRGDSEEASGAEEEVGTVAAAA 819
            +E    EE E EE   D   +DS    GSE+  E   S   DS+  S  +E+        
Sbjct: 1811 QETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDE----- 1865

Query: 820  TAGKEMDSNEKTTQQSSLPPPPPPDSLDQPQPMEQGSSGVLGGKEEGGKPERSSSPASAL 879
                E +S ++ ++ SS  PPP P     P  +   SS +LG       P+   +PAS  
Sbjct: 1866 ---DEEESQDELSRPSSEAPPPGP-----PHALRADSSPILG-------PQPPDAPASG- 1909

Query: 880  TPEGEATSVTLVEELS 895
            T     +SV+  E L+
Sbjct: 1910 TEATRGSSVSEAERLT 1925



 Score = 38.9 bits (89), Expect = 0.025
 Identities = 109/442 (24%), Positives = 159/442 (35%), Gaps = 78/442 (17%)

Query: 518 EPKNKADENTPPGSEGSAISGVAESSTATRMQLSKLVTSLPSWA--LLTNHFKSTGSFPF 575
           EP +   E T P  E S +S     STA  + L +   S+PS A  + T H    GS+ F
Sbjct: 507 EPLSSHSEKTKP--EQSLLSLQHPPSTAPPVPLLRS-HSMPSAACTISTPHHPFRGSYSF 563

Query: 576 PYVLEPLGASPSETSKLQQLVEKIDRQGAVAVTSAASGAPTTSAPAPSSS-ASSGPNQCV 634
              +    A    +         + RQ A+ +     G  ++  P PSS   +S P+  V
Sbjct: 564 DDHITDSEALSHSSHVFTSHPRMLKRQPAIELP--LGGEYSSEEPGPSSKDTASKPSDEV 621

Query: 635 ICLRVLSCPRALRLHYGQHGGERP----FKCKVCGRAFSTRGNLRAHFVGH-----KASP 685
                   P+   L      G +     ++C +CG  +  R N  AH   +      A P
Sbjct: 622 E-------PKESELTKKTKKGLKTKGVIYECNICGARYKKRDNYEAHKKYYCSELQIAKP 674

Query: 686 AARAQNSCPICQKKFTNAVTLQQHVRMHLGGQI---PNGGTALPEGGGAAQENGSEQSTV 742
            +   ++ P  +K         Q +   LG  +   P       +  G  +E  + +ST 
Sbjct: 675 ISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLELTPLRKRRKEKSLGDEEEPPAFESTK 734

Query: 743 SGAGSFPQQQSQQPSPEEELSEEEEEEDE----EEEEDVTDEDSLAGRGSESGGE----- 793
           S  GS     + +  P E      E        E            G GSESG E     
Sbjct: 735 SQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKPGSGSESGKERRTTS 794

Query: 794 KAISV--------RGDS-EEASGAEEEVGTVA-----AAATAGKEMDS-NEKTTQQSSL- 837
           K ISV        + DS E+ SG E E   +A       A  G+   S   K  +Q ++ 
Sbjct: 795 KEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPPPAPHGRSAHSLQPKLVRQPNIQ 854

Query: 838 -------PPPPPPDSLDQPQPMEQGSSGVLGGKEEGGKPERSSS----PASALTPEGEAT 886
                    P  PD+  +P P E   +      EE   P+RS +    PA  L P+    
Sbjct: 855 VPEILVTEEPDRPDTEPEPPPKEPEKT------EEFQWPQRSQTLAQLPAEKLPPK---- 904

Query: 887 SVTLVEELSLQEAMRKEPGESS 908
                + L L E M +  GESS
Sbjct: 905 ----KKRLRLAE-MAQSSGESS 921



 Score = 38.9 bits (89), Expect = 0.025
 Identities = 41/158 (25%), Positives = 66/158 (41%), Gaps = 13/158 (8%)

Query: 810  EEVGTVAAAA--TAGKEMDSNEKTTQQSSLPPPPPPDSLDQPQPMEQGSSGVLGGKEEGG 867
            +E  T+A A    AG+ + S+ +  + + +  P    SL  P+  ++  + V   +E  G
Sbjct: 1659 KETYTMATAPHPEAGRLVPSSSRKPRMTEVHLP----SLVSPEG-QKDLARVEKEEERRG 1713

Query: 868  KPERSSSPASALTPEGEATSVTLVEE-LSLQEAMRKEPGESSSRKACEVCGQAFPSQAAL 926
            +PE  + PAS     GE   + + E      E      G    +  CE CG      + L
Sbjct: 1714 EPEEDA-PASQ---RGEPARIKIFEGGYKSNEEYVYVRGRGRGKYVCEECGIRCKKPSML 1769

Query: 927  EEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAHH 964
            ++H +TH    P + C  C   F  +  L KHM    H
Sbjct: 1770 KKHIRTHTDVRP-YVCKHCHFAFKTKGNLTKHMKSKAH 1806



 Score = 36.6 bits (83), Expect = 0.12
 Identities = 23/99 (23%), Positives = 41/99 (41%), Gaps = 5/99 (5%)

Query: 869 PERSSSPASALTPEGEATSVTLVEELSLQEAMRKEPGESSSRKACEVCGQAFPSQAALEE 928
           PE          P     S+   EE   +E   ++PG    +  C+ C +     + L++
Sbjct: 154 PEDLPGVPKVFVPRPSQVSLKPTEEAHKKERKPQKPG----KYICQYCSRPCAKPSVLQK 209

Query: 929 HQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAHHQVQ 967
           H ++H  E P + C  C   F  ++ L KH     H+++
Sbjct: 210 HIRSHTGERP-YPCGPCGFSFKTKSNLYKHRKSHAHRIK 247



 Score = 35.4 bits (80), Expect = 0.27
 Identities = 60/260 (23%), Positives = 92/260 (35%), Gaps = 55/260 (21%)

Query: 103  GSSVPTDPTWGPERRGEES----------PGHFLVAATGTAAGGGGG------------- 139
            G++ P  P + P RR              PG + +A  G+ + G  G             
Sbjct: 2057 GTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPP 2116

Query: 140  ------LILASPKLGATPLPPES-----TPAPPPPPPPPPPPGVGSGHLNIPLILEELRV 188
                  L+  SP+  A+P   ES     +P P  P    P   +   H +I    EE  +
Sbjct: 2117 APLPHKLLSRSPETCASPWKAESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEE-NI 2175

Query: 189  LQQRQIHQMQMTEQICRQVLLLGSLGQTVGAP-ASPSELPG------TGTASSTKPLLPL 241
                 +H   +T   C  ++ +G +      P A P+ LPG      +G +     L   
Sbjct: 2176 FSHLPLHSQHLTRAPC-PLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGGGSDLTGA 2234

Query: 242  FSPIKPVQTSKTLASSSSSS-----------SSSSGAETPKQAFFHLYHPLGSQHPFSAG 290
                +  + S T +SS+S S           S   G + PK+       P G    ++  
Sbjct: 2235 REAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGP-GRPPDWTPH 2293

Query: 291  GVGRSHKPTPAPSPALPGST 310
            G G   +PTP  SP  P  T
Sbjct: 2294 GTGAPAEPTPTHSPCTPPDT 2313



 Score = 31.2 bits (69), Expect = 5.1
 Identities = 36/159 (22%), Positives = 58/159 (36%), Gaps = 22/159 (13%)

Query: 693 CPICQKKFTNAVTLQQHVRMHLGGQ-IPNG--GTALPEGGGAAQENGSEQSTV-----SG 744
           C  C +       LQ+H+R H G +  P G  G +        +   S    +     SG
Sbjct: 194 CQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSHAHRIKAGLASG 253

Query: 745 AGS--FPQQQSQQPSPEEELSEEEEEEDEEEEEDVTDEDSLAGRGSESGGEKAISVRGDS 802
            G   +P     +  P EE  E  E E  + EE+ +         + SG    +S R   
Sbjct: 254 MGGEMYPHGLEMERIPGEEFEEPTEGESTDSEEETS---------ATSGHPAELSPRPKQ 304

Query: 803 EEASGAEEEVGTVAAAATAGKEMDSNEKTTQQSSLPPPP 841
              S      G   + +++ +    ++ +T QS   PPP
Sbjct: 305 PLLSSGLYSSG---SHSSSHERCSLSQSSTAQSLEDPPP 340


>gi|116089331 human immunodeficiency virus type I enhancer binding
           protein 3 [Homo sapiens]
          Length = 2406

 Score = 78.6 bits (192), Expect = 3e-14
 Identities = 116/429 (27%), Positives = 171/429 (39%), Gaps = 103/429 (24%)

Query: 205 RQVLLLGSLGQTVGAPASPSELPGTGTASSTK-PLLPLFSPIKPVQTSKTLASSSSSSSS 263
           R+ L  G   QT  + + P   PG+GTA++ + P   L +P +P     ++    S   +
Sbjct: 18  RKRLTKGEAIQTSVSSSVP--YPGSGTAATQESPAQELLAP-QPFPGPSSVLREGSQEKT 74

Query: 264 SSGAETPK----QAFFHLYHPLGSQHPFSAGGVGRSHKPTPA------PSPALPGSTDQL 313
               + PK    +A  H+     SQ P         H  TPA      P   L GST QL
Sbjct: 75  GQQQKPPKRPPIEASVHI-----SQLP--------QHPLTPAFMSPGKPEHLLEGSTWQL 121

Query: 314 I-----------ASPHL-----AFPSTTGLLAAQCL-GAARGLEATASPGLLKPKNGSGE 356
           +            +P L       PS   ++  + L G  +      S   LKP     E
Sbjct: 122 VDPMRPGPSGSFVAPGLHPQSQLLPSHASIIPPEDLPGVPKVFVPRPSQVSLKPT----E 177

Query: 357 LSYGEVMGPLEKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNL 416
            ++ +   P +KPG ++ C++C++     S LQ H+RSHTGERPY C  CG  F T+ NL
Sbjct: 178 EAHKKERKP-QKPG-KYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNL 235

Query: 417 KVH--FHRHR-----------EKYPH-VQMNPHPVPEHLDYVITSSGLPYGMSVPPEKAE 462
             H   H HR           E YPH ++M   P  E  +     S          +  E
Sbjct: 236 YKHRKSHAHRIKAGLASGMGGEMYPHGLEMERIPGEEFEEPTEGES---------TDSEE 286

Query: 463 EEAATPGGGVE-----RKPLVASTTALSATESLT----LLSTSAGTATAPGLPAF----- 508
           E +AT G   E     ++PL++S    S + S +     LS S+   +    P F     
Sbjct: 287 ETSATSGHPAELSPRPKQPLLSSGLYSSGSHSSSHERCSLSQSSTAQSLEDPPPFVEPSS 346

Query: 509 --------------NKFVLMKAVEPKNKADENT--PPGSEGSAISGVAESSTATRMQLSK 552
                          + + ++  E K   DE     PGS+GS  SG    S +   Q+S 
Sbjct: 347 EHPLSHKPEDTHTIKQKLALRLSERKKVIDEQAFLSPGSKGSTESGYFSRSESAEQQVSP 406

Query: 553 LVTSLPSWA 561
             T+  S+A
Sbjct: 407 PNTNAKSYA 415



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 20/49 (40%), Positives = 25/49 (51%)

Query: 633 CVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGH 681
           C  C R  + P  L+ H   H GERP+ C  CG +F T+ NL  H   H
Sbjct: 194 CQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSH 242



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 61/249 (24%), Positives = 86/249 (34%), Gaps = 41/249 (16%)

Query: 643  PRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARAQNSCPICQKKFTN 702
            P  L+ H   H   RP+ CK C  AF T+GNL  H      S             KK   
Sbjct: 1766 PSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHS-------------KKCQE 1812

Query: 703  AVTLQQHVRMHLGGQIPNGGTALPEGGGAAQENGSEQSTVSGAGSFPQQQSQQPSPEEEL 762
               L++                L    G + +   +     G+ +  + Q       +  
Sbjct: 1813 TGVLEE----------------LEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSD 1856

Query: 763  SEEEEEEDEEEEEDVTDEDSLAGRGSES---GGEKAISVRGDSEEASGAE-EEVGTVAAA 818
            S+ +E+EDE+EEE    +D L+   SE+   G   A+  R DS    G +  +       
Sbjct: 1857 SDLDEDEDEDEEE---SQDELSRPSSEAPPPGPPHAL--RADSSPILGPQPPDAPASGTE 1911

Query: 819  ATAGKEMDSNEKTTQQSSLPPPPPPDSLDQPQPMEQGSSGVLGGKEEGGKPERSSSPASA 878
            AT G  +   E+ T  S          L    P   GS     G     KP    SP   
Sbjct: 1912 ATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKP---VSPRRP 1968

Query: 879  LTPEGEATS 887
             +P  EA S
Sbjct: 1969 WSPSKEAGS 1977



 Score = 43.9 bits (102), Expect = 8e-04
 Identities = 20/49 (40%), Positives = 26/49 (53%)

Query: 371  GRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVH 419
            G++ C  C       S L+ H+R+HT  RPY C  C   F T+GNL  H
Sbjct: 1752 GKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKH 1800



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 40/136 (29%), Positives = 58/136 (42%), Gaps = 21/136 (15%)

Query: 760  EELSEEEEEEDEEEEEDVTDEDSLAGRGSESGGEKAISVRGDSEEASGAEEEVGTVAAAA 819
            +E    EE E EE   D   +DS    GSE+  E   S   DS+  S  +E+        
Sbjct: 1811 QETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDE----- 1865

Query: 820  TAGKEMDSNEKTTQQSSLPPPPPPDSLDQPQPMEQGSSGVLGGKEEGGKPERSSSPASAL 879
                E +S ++ ++ SS  PPP P     P  +   SS +LG       P+   +PAS  
Sbjct: 1866 ---DEEESQDELSRPSSEAPPPGP-----PHALRADSSPILG-------PQPPDAPASG- 1909

Query: 880  TPEGEATSVTLVEELS 895
            T     +SV+  E L+
Sbjct: 1910 TEATRGSSVSEAERLT 1925



 Score = 38.9 bits (89), Expect = 0.025
 Identities = 109/442 (24%), Positives = 159/442 (35%), Gaps = 78/442 (17%)

Query: 518 EPKNKADENTPPGSEGSAISGVAESSTATRMQLSKLVTSLPSWA--LLTNHFKSTGSFPF 575
           EP +   E T P  E S +S     STA  + L +   S+PS A  + T H    GS+ F
Sbjct: 507 EPLSSHSEKTKP--EQSLLSLQHPPSTAPPVPLLRS-HSMPSAACTISTPHHPFRGSYSF 563

Query: 576 PYVLEPLGASPSETSKLQQLVEKIDRQGAVAVTSAASGAPTTSAPAPSSS-ASSGPNQCV 634
              +    A    +         + RQ A+ +     G  ++  P PSS   +S P+  V
Sbjct: 564 DDHITDSEALSHSSHVFTSHPRMLKRQPAIELP--LGGEYSSEEPGPSSKDTASKPSDEV 621

Query: 635 ICLRVLSCPRALRLHYGQHGGERP----FKCKVCGRAFSTRGNLRAHFVGH-----KASP 685
                   P+   L      G +     ++C +CG  +  R N  AH   +      A P
Sbjct: 622 E-------PKESELTKKTKKGLKTKGVIYECNICGARYKKRDNYEAHKKYYCSELQIAKP 674

Query: 686 AARAQNSCPICQKKFTNAVTLQQHVRMHLGGQI---PNGGTALPEGGGAAQENGSEQSTV 742
            +   ++ P  +K         Q +   LG  +   P       +  G  +E  + +ST 
Sbjct: 675 ISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLELTPLRKRRKEKSLGDEEEPPAFESTK 734

Query: 743 SGAGSFPQQQSQQPSPEEELSEEEEEEDE----EEEEDVTDEDSLAGRGSESGGE----- 793
           S  GS     + +  P E      E        E            G GSESG E     
Sbjct: 735 SQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKPGSGSESGKERRTTS 794

Query: 794 KAISV--------RGDS-EEASGAEEEVGTVA-----AAATAGKEMDS-NEKTTQQSSL- 837
           K ISV        + DS E+ SG E E   +A       A  G+   S   K  +Q ++ 
Sbjct: 795 KEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPPPAPHGRSAHSLQPKLVRQPNIQ 854

Query: 838 -------PPPPPPDSLDQPQPMEQGSSGVLGGKEEGGKPERSSS----PASALTPEGEAT 886
                    P  PD+  +P P E   +      EE   P+RS +    PA  L P+    
Sbjct: 855 VPEILVTEEPDRPDTEPEPPPKEPEKT------EEFQWPQRSQTLAQLPAEKLPPK---- 904

Query: 887 SVTLVEELSLQEAMRKEPGESS 908
                + L L E M +  GESS
Sbjct: 905 ----KKRLRLAE-MAQSSGESS 921



 Score = 38.9 bits (89), Expect = 0.025
 Identities = 41/158 (25%), Positives = 66/158 (41%), Gaps = 13/158 (8%)

Query: 810  EEVGTVAAAA--TAGKEMDSNEKTTQQSSLPPPPPPDSLDQPQPMEQGSSGVLGGKEEGG 867
            +E  T+A A    AG+ + S+ +  + + +  P    SL  P+  ++  + V   +E  G
Sbjct: 1659 KETYTMATAPHPEAGRLVPSSSRKPRMTEVHLP----SLVSPEG-QKDLARVEKEEERRG 1713

Query: 868  KPERSSSPASALTPEGEATSVTLVEE-LSLQEAMRKEPGESSSRKACEVCGQAFPSQAAL 926
            +PE  + PAS     GE   + + E      E      G    +  CE CG      + L
Sbjct: 1714 EPEEDA-PASQ---RGEPARIKIFEGGYKSNEEYVYVRGRGRGKYVCEECGIRCKKPSML 1769

Query: 927  EEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAHH 964
            ++H +TH    P + C  C   F  +  L KHM    H
Sbjct: 1770 KKHIRTHTDVRP-YVCKHCHFAFKTKGNLTKHMKSKAH 1806



 Score = 36.6 bits (83), Expect = 0.12
 Identities = 23/99 (23%), Positives = 41/99 (41%), Gaps = 5/99 (5%)

Query: 869 PERSSSPASALTPEGEATSVTLVEELSLQEAMRKEPGESSSRKACEVCGQAFPSQAALEE 928
           PE          P     S+   EE   +E   ++PG    +  C+ C +     + L++
Sbjct: 154 PEDLPGVPKVFVPRPSQVSLKPTEEAHKKERKPQKPG----KYICQYCSRPCAKPSVLQK 209

Query: 929 HQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAHHQVQ 967
           H ++H  E P + C  C   F  ++ L KH     H+++
Sbjct: 210 HIRSHTGERP-YPCGPCGFSFKTKSNLYKHRKSHAHRIK 247



 Score = 34.3 bits (77), Expect = 0.61
 Identities = 59/261 (22%), Positives = 91/261 (34%), Gaps = 56/261 (21%)

Query: 103  GSSVPTDPTWGPERRGEES----------PGHFLVAATGTAAGGGGG------------- 139
            G++ P  P + P RR              PG + +A  G+ + G  G             
Sbjct: 2057 GTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPP 2116

Query: 140  ------LILASPKLGATPLP------PESTPAPPPPPPPPPPPGVGSGHLNIPLILEELR 187
                  L+  SP+  A+P        P  +P P  P    P   +   H +I    EE  
Sbjct: 2117 APLPHKLLSRSPETCASPWQKAESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEE-N 2175

Query: 188  VLQQRQIHQMQMTEQICRQVLLLGSLGQTVGAP-ASPSELPG------TGTASSTKPLLP 240
            +     +H   +T   C  ++ +G +      P A P+ LPG      +G +     L  
Sbjct: 2176 IFSHLPLHSQHLTRAPC-PLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGGGSDLTG 2234

Query: 241  LFSPIKPVQTSKTLASSSSSS-----------SSSSGAETPKQAFFHLYHPLGSQHPFSA 289
                 +  + S T +SS+S S           S   G + PK+       P G    ++ 
Sbjct: 2235 AREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGP-GRPPDWTP 2293

Query: 290  GGVGRSHKPTPAPSPALPGST 310
             G G   +PTP  SP  P  T
Sbjct: 2294 HGTGAPAEPTPTHSPCTPPDT 2314



 Score = 31.2 bits (69), Expect = 5.1
 Identities = 36/159 (22%), Positives = 58/159 (36%), Gaps = 22/159 (13%)

Query: 693 CPICQKKFTNAVTLQQHVRMHLGGQ-IPNG--GTALPEGGGAAQENGSEQSTV-----SG 744
           C  C +       LQ+H+R H G +  P G  G +        +   S    +     SG
Sbjct: 194 CQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSHAHRIKAGLASG 253

Query: 745 AGS--FPQQQSQQPSPEEELSEEEEEEDEEEEEDVTDEDSLAGRGSESGGEKAISVRGDS 802
            G   +P     +  P EE  E  E E  + EE+ +         + SG    +S R   
Sbjct: 254 MGGEMYPHGLEMERIPGEEFEEPTEGESTDSEEETS---------ATSGHPAELSPRPKQ 304

Query: 803 EEASGAEEEVGTVAAAATAGKEMDSNEKTTQQSSLPPPP 841
              S      G   + +++ +    ++ +T QS   PPP
Sbjct: 305 PLLSSGLYSSG---SHSSSHERCSLSQSSTAQSLEDPPP 340


>gi|51173737 ras responsive element binding protein 1 isoform 1 [Homo
            sapiens]
          Length = 1742

 Score = 76.6 bits (187), Expect = 1e-13
 Identities = 126/605 (20%), Positives = 210/605 (34%), Gaps = 84/605 (13%)

Query: 424  REKYPHVQMNPHPVPEHLDYVITSSGLPYGMSVPPEKAEEEAATPGGGVERKPLVASTTA 483
            R K P +   P PV E L  + + + +   +S  P   + + A PG         AS + 
Sbjct: 1046 RPKPPLLLPKP-PVTEELPPLASIAQIISSVSSAPTLLKTKVADPGPASTGSNTTASDSL 1104

Query: 484  LSATESLTLLSTSAGTATAPGLPAFNKFVLMKAVEPKNKADENTPPGS-EGSAISGVAES 542
              +       +T A T +                 PK  ++   P  S E ++ +    +
Sbjct: 1105 GGSVPKAATTATPAATTS-----------------PKESSEPPAPASSPEAASPTEQGPA 1147

Query: 543  STATRMQLSKLVTSLPSWALLTNHFKSTGSFPFPYVLEPLGASPSETSKLQQLVEKID-- 600
             T+ +    + + S P          S+G F     +E + A+ ++T+K    ++  +  
Sbjct: 1148 GTSKKRGRKRGMRSRPRANSGGVDLDSSGEFAS---IEKMLAT-TDTNKFSPFLQTAEDN 1203

Query: 601  RQGAVAVTSAASGAPTTS---APAPSSSASSGPNQCVICLRVLSCPR---------ALRL 648
             Q  VA   A    P+     +P       +  N    CL+ ++CP          +L+ 
Sbjct: 1204 TQDEVAGAPADHHGPSDEEQGSPPEDKLLRAKRNSYTNCLQKITCPHCPRVFPWASSLQR 1263

Query: 649  HYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARAQNSCPICQKKFTNAVTLQQ 708
            H   H G++PF C+ C   FST+ N   H +          + +  I Q K ++  +   
Sbjct: 1264 HMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTCSLRRNGLIPQSKESDVGSHDS 1323

Query: 709  HVRMHLGGQIPNGGTAL---PEGGGAAQENGSEQSTVSGAGSFPQQQSQQPSPEEELSEE 765
                         G  L           E  +E   V+G     Q  ++  SP       
Sbjct: 1324 TDSQSDAETAAAAGEVLDLTSRDREQPSEGATELRQVAGDAPVEQATAETASPVHREEHG 1383

Query: 766  EEEEDEEEEEDVTDEDSLAGRGSESGGEKAISV--------------RGDSEEASG--AE 809
              E  E EEE  T+E +    G+E       S+               GD E  +G  A 
Sbjct: 1384 RGESHEPEEEHGTEESTGDADGAEEDASSNQSLDLDFATKLMDFKLAEGDGEAGAGGAAS 1443

Query: 810  EE--------------VGTVAAAATA-GKEMDSNEKTTQQSSLPPPPPPDSLDQPQPMEQ 854
            +E              +GT++    A G++   +EK    S+    P P    + +P E 
Sbjct: 1444 QEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQEEKPPET 1503

Query: 855  GSSGVLGGKEEGGKPERSSSPASALTPEGEATSVTLVEELSLQEAMRKEPGESS------ 908
             +  V      G  P    +  +    +GE+ +     E S  +   K     S      
Sbjct: 1504 PAEVVESAPGAGEAPAEKLAEETEGPSDGESAAEKRSSEKSDDDKKPKTDSPKSVASKAD 1563

Query: 909  -SRKACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAHHQVQ 967
              +K C VC + F S   L  H ++H  E P + C  C     ER    KH L+ H ++ 
Sbjct: 1564 KRKKVCSVCNKRFWSLQDLTRHMRSHTGERP-YKCQTC-----ERTFTLKHSLVRHQRIH 1617

Query: 968  PFAPH 972
              A H
Sbjct: 1618 QKARH 1622



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 30/60 (50%), Positives = 35/60 (58%), Gaps = 1/60 (1%)

Query: 370 GGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPH 429
           G  H C  C K   S S+L  H+  H+GERPYKC VCG  FTT GN+  H   H EK P+
Sbjct: 94  GADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIH-EKDPN 152



 Score = 58.2 bits (139), Expect = 4e-08
 Identities = 41/209 (19%), Positives = 84/209 (40%), Gaps = 22/209 (10%)

Query: 581 PLGASPSETSKLQQLVEKIDRQGAVAVTSAASGAPTTSAPAPSSSASSGPNQ-------- 632
           P G   S+ S +  ++  +   G V     +     + +  P  +     NQ        
Sbjct: 6   PAGLEGSDLSSINTMMSAVMSVGKVTENGGSPQGIKSPSKPPGPNRIGRRNQETKEEKSS 65

Query: 633 --CVICLRVLSCPRALRLHYGQHG---GERPFKCKVCGRAFSTRGNLRAHFVGHKASPAA 687
             C +C ++ +    L +H  QH    G     C +CG++ S+  +L  H + H      
Sbjct: 66  YNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPY 125

Query: 688 RAQNSCPICQKKFTNAVTLQQHVRMHLGGQIPNGGTALPEGGGAAQENGSEQSTVSGAGS 747
           +    C +C + FT    + +H+++H   + PN  TA        +   S +  +S    
Sbjct: 126 K----CTVCGQSFTTNGNMHRHMKIH--EKDPNSATATAPPSPLKRRRLSSKRKLSHDA- 178

Query: 748 FPQQQSQQPSPEEELSEEEEEEDEEEEED 776
             + + + P+P +++ E+ +  D E++ D
Sbjct: 179 --ESEREDPAPAKKMVEDGQSGDLEKKAD 205



 Score = 57.0 bits (136), Expect = 9e-08
 Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 9/84 (10%)

Query: 356 ELSYGEVMGPLEKPGGR---------HKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVC 406
           E++ GE+   +  PGG+         + CRFC +VF     L+ H+RSH G  PY+CN+C
Sbjct: 617 EITEGELKAFMTAPGGKKTPAMRKVLYPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNIC 676

Query: 407 GNRFTTRGNLKVHFHRHREKYPHV 430
                 +  L  H   H  + P++
Sbjct: 677 DYIAADKAALIRHLRTHSGERPYI 700



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 44/150 (29%), Positives = 61/150 (40%), Gaps = 7/150 (4%)

Query: 282  GSQHPFSAGGVGRSH-----KPTPAPSPALPGSTDQLIASPHLAFPSTTGLLAAQCLGAA 336
            G Q P    G G S      +P P      P +  +++ S   A  +    LA +  G +
Sbjct: 1471 GRQEPKDEKGDGASTAEEGPQPAPEQEEKPPETPAEVVESAPGAGEAPAEKLAEETEGPS 1530

Query: 337  RGLEATASPGLLKPKNGSGELSYGEVMGPLEKPGGRHK-CRFCAKVFGSDSALQIHLRSH 395
             G E+ A     +  +   +           K   R K C  C K F S   L  H+RSH
Sbjct: 1531 DG-ESAAEKRSSEKSDDDKKPKTDSPKSVASKADKRKKVCSVCNKRFWSLQDLTRHMRSH 1589

Query: 396  TGERPYKCNVCGNRFTTRGNLKVHFHRHRE 425
            TGERPYKC  C   FT + +L  H   H++
Sbjct: 1590 TGERPYKCQTCERTFTLKHSLVRHQRIHQK 1619



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 23/76 (30%), Positives = 42/76 (55%), Gaps = 5/76 (6%)

Query: 373 HKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPHVQM 432
           ++C  C  +    +AL  HLR+H+GERPY C +C   FT + N + H  +      H++ 
Sbjct: 671 YQCNICDYIAADKAALIRHLRTHSGERPYICKICHYPFTVKANCERHLRK-----KHLKA 725

Query: 433 NPHPVPEHLDYVITSS 448
               + ++++YV +S+
Sbjct: 726 TRKDIEKNIEYVSSSA 741



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 85/324 (26%), Positives = 126/324 (38%), Gaps = 64/324 (19%)

Query: 141  ILASPKLGATPLPPESTPAPPPPPPPPP---------------PPGVGSGHL-NIPLILE 184
            IL SP   A    P +TP PP  P   P               PP VGS  L +   +L 
Sbjct: 988  ILESPMAPA----PAATPEPPAQPLQGPVQLAVPIYSSALVSSPPLVGSSALLSGTALLR 1043

Query: 185  ELRVLQQRQIHQMQMTEQICRQVLLLGSLGQTVGAPASPSEL-------PG-TGTASSTK 236
             LR      + +  +TE++      L S+ Q + + +S   L       PG   T S+T 
Sbjct: 1044 PLRPKPPLLLPKPPVTEELPP----LASIAQIISSVSSAPTLLKTKVADPGPASTGSNTT 1099

Query: 237  PLLPLFSPIKPVQTSKTLASSSSSSSSS---SGAETPKQAFFHLYHPLG----------- 282
                L   +    T+ T A+++S   SS   + A +P+ A      P G           
Sbjct: 1100 ASDSLGGSVPKAATTATPAATTSPKESSEPPAPASSPEAASPTEQGPAGTSKKRGRKRGM 1159

Query: 283  -SQHPFSAGGVGRSHKPTPAPSPALPGSTDQLIASPHL--AFPSTTGLLA-AQCLGAARG 338
             S+   ++GGV        A    +  +TD    SP L  A  +T   +A A        
Sbjct: 1160 RSRPRANSGGVDLDSSGEFASIEKMLATTDTNKFSPFLQTAEDNTQDEVAGAPADHHGPS 1219

Query: 339  LEATASPG---LLKPKNGSGELSYGEVMGPLEKPGGRHKCRFCAKVFGSDSALQIHLRSH 395
             E   SP    LL+ K  S    Y   +  +        C  C +VF   S+LQ H+ +H
Sbjct: 1220 DEEQGSPPEDKLLRAKRNS----YTNCLQKIT-------CPHCPRVFPWASSLQRHMLTH 1268

Query: 396  TGERPYKCNVCGNRFTTRGNLKVH 419
            TG++P+ C  C   F+T+ N + H
Sbjct: 1269 TGQKPFPCQKCDAFFSTKSNCERH 1292



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 30/114 (26%), Positives = 47/114 (41%), Gaps = 22/114 (19%)

Query: 630 PNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHF----------- 678
           P QC IC  + +   AL  H   H GERP+ CK+C   F+ + N   H            
Sbjct: 670 PYQCNICDYIAADKAALIRHLRTHSGERPYICKICHYPFTVKANCERHLRKKHLKATRKD 729

Query: 679 ----VGHKASPAARAQNS-------CPICQKKFTNAVTLQQHVRMHLGGQIPNG 721
               + + +S AA   ++       C +C +   +   L+ H+R H G  +  G
Sbjct: 730 IEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDLKHYRALRIHMRTHCGRGLGGG 783



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 23/75 (30%), Positives = 37/75 (49%), Gaps = 1/75 (1%)

Query: 615  PTTSAP-APSSSASSGPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGN 673
            P T +P + +S A      C +C +     + L  H   H GERP+KC+ C R F+ + +
Sbjct: 1550 PKTDSPKSVASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHS 1609

Query: 674  LRAHFVGHKASPAAR 688
            L  H   H+ +  A+
Sbjct: 1610 LVRHQRIHQKARHAK 1624



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 27/95 (28%), Positives = 39/95 (41%), Gaps = 8/95 (8%)

Query: 912  ACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAHHQVQP--- 968
            +C +CG++  S ++L+ H   H  E P + C  C Q F     + +HM +  H+  P   
Sbjct: 98   SCSICGKSLSSASSLDRHMLVHSGERP-YKCTVCGQSFTTNGNMHRHMKI--HEKDPNSA 154

Query: 969  --FAPHGPQNIAALSLVPGCSPSITSTGLSPFPRK 1001
               AP  P     LS     S    S    P P K
Sbjct: 155  TATAPPSPLKRRRLSSKRKLSHDAESEREDPAPAK 189



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 53/240 (22%), Positives = 87/240 (36%), Gaps = 33/240 (13%)

Query: 475 KPLVASTTALSATESLTLLSTSAGT--ATAPGLPAFNKFVLMKAVEPKNKADE-NTPPGS 531
           KPLV   T ++ +    L++    +    +P LP     +L  +VE  + A    +  G+
Sbjct: 510 KPLVTPRTVVATSTPPPLINAQQASPGCISPSLPPPPLKLLKGSVEAASNAHLLQSKSGT 569

Query: 532 EGSAISGVAESSTATRMQLSKLVTSLPSWALLTNHFKSTGSFPFPYVLEPLGASPSETSK 591
           +  A         ATR+ L +    LP    +    +         ++E L     E   
Sbjct: 570 QPHA---------ATRLSLQQPRAELPGQPEMKTQLEQDS------IIEALLPLSMEAKI 614

Query: 592 LQQLVEKIDRQGAVAVTSAASGAPTTSAPAPSSSASSGPNQCVICLRVLSCPRALRLHYG 651
            Q++ E     G +     A G   T    P+      P  C  C +V +    LR H  
Sbjct: 615 KQEITE-----GELKAFMTAPGGKKT----PAMRKVLYP--CRFCNQVFAFSGVLRAHVR 663

Query: 652 QHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARAQNSCPICQKKFTNAVTLQQHVR 711
            H G  P++C +C    + +  L  H   H    +      C IC   FT     ++H+R
Sbjct: 664 SHLGISPYQCNICDYIAADKAALIRHLRTH----SGERPYICKICHYPFTVKANCERHLR 719



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 24/111 (21%), Positives = 45/111 (40%), Gaps = 4/111 (3%)

Query: 323 STTGLLAAQCLGAARGLEATASP-GLLKPKNGSGELSYGEVMGPLEKPGGRHKCRFCAKV 381
           S+   + +  +   +  E   SP G+  P    G    G      ++    + C  C K+
Sbjct: 15  SSINTMMSAVMSVGKVTENGGSPQGIKSPSKPPGPNRIGRRNQETKEEKSSYNCPLCEKI 74

Query: 382 FGSDSALQIHLRSH---TGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPH 429
             +   L +H+R H   TG   + C++CG   ++  +L  H   H  + P+
Sbjct: 75  CTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPY 125



 Score = 38.1 bits (87), Expect = 0.042
 Identities = 20/56 (35%), Positives = 27/56 (48%), Gaps = 9/56 (16%)

Query: 633 CVICLRVLSCPRALRLHY---------GQHGGERPFKCKVCGRAFSTRGNLRAHFV 679
           C +C   L   RALR+H          G H G +PF+CK C  AF+ + N   H +
Sbjct: 755 CRLCGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHIL 810



 Score = 37.0 bits (84), Expect = 0.093
 Identities = 28/104 (26%), Positives = 43/104 (41%), Gaps = 22/104 (21%)

Query: 375 CRFCAKVFGSDSALQIHLRS---------HTGERPYKCNVCGNRFTTRGNLKVHFHRHRE 425
           CR C +      AL+IH+R+         H G +P++C  C   F  + N     H   +
Sbjct: 755 CRLCGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNC---IHHILK 811

Query: 426 KYPHVQMNPHPVPEHLDYVITSSGLPYGMSVPPEKAEEEAATPG 469
           ++ HV     P  +   YV+ + GL      P E    EA+  G
Sbjct: 812 QHLHV-----PEQDIESYVLAADGLG-----PAEAPAAEASGRG 845



 Score = 35.4 bits (80), Expect = 0.27
 Identities = 16/51 (31%), Positives = 24/51 (47%), Gaps = 1/51 (1%)

Query: 913 CEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAH 963
           C +C      +AAL  H +TH  E P + C  C   F  +A  ++H+   H
Sbjct: 673 CNICDYIAADKAALIRHLRTHSGERP-YICKICHYPFTVKANCERHLRKKH 722



 Score = 34.7 bits (78), Expect = 0.46
 Identities = 18/54 (33%), Positives = 25/54 (46%), Gaps = 2/54 (3%)

Query: 633 CVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFST-RGNLRAHFVGHKASP 685
           C +C +   C   L  H   H  + P +C +C   F T RG LR + + HK  P
Sbjct: 210 CPVCFKEFVCKYGLETHMETHS-DNPLRCDICCVTFRTHRGLLRHNALVHKQLP 262



 Score = 33.5 bits (75), Expect = 1.0
 Identities = 22/68 (32%), Positives = 30/68 (44%), Gaps = 8/68 (11%)

Query: 913 CEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAHHQV------ 966
           C VC + F  +  LE H +TH  + PL  C  C   F     L +H  L H Q+      
Sbjct: 210 CPVCFKEFVCKYGLETHMETH-SDNPL-RCDICCVTFRTHRGLLRHNALVHKQLPRDAMG 267

Query: 967 QPFAPHGP 974
           +PF  + P
Sbjct: 268 RPFIQNNP 275



 Score = 33.1 bits (74), Expect = 1.3
 Identities = 83/384 (21%), Positives = 130/384 (33%), Gaps = 71/384 (18%)

Query: 372 RHKCRFCAKVFGSDSALQIHLRSHTG-----ERPYKCNVCGNRFTTRGNLKVHFHRHREK 426
           R  C  C K F    +L +H ++H       E+P    + G+    +G L +   +H + 
Sbjct: 315 RFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKPQATPLPGDALDQKGFLALLGLQHTK- 373

Query: 427 YPHVQMNPHPVPEHLDYVITSSGLPYGMSVPPEKAEEEAATPGGGVERKPLVASTTALSA 486
                + P P  E L               P +    +  T    + + P   +  +LS 
Sbjct: 374 ----DVRPAPAEEPL---------------PDDNQAIQLQTLKCQLPQDPGCTNLLSLSP 414

Query: 487 TESLTLLSTSAGTATAPGLPAFNKFVLMKAVEPKNKADENTPPGS-EGSAISGVAESSTA 545
            E+ +L     G+ T   LPA    +   +++P  K     P  S     ISG +    A
Sbjct: 415 FEAASL----GGSLTV--LPATKDSIKHLSLQPFQKGFIIQPDSSIVVKPISGESAIELA 468

Query: 546 TRMQLSKLVTSLPSWALLTNHFKSTGSFPFPYVLE---PLGASPSETSKLQQLVEKIDRQ 602
              Q+ K+  S P    L    K+  + P   + +   PL   P  T +   +V      
Sbjct: 469 DIQQILKMAASAPPQISLPPFSKAPAA-PLQAIFKHMPPLKPKPLVTPRT--VVATSTPP 525

Query: 603 GAVAVTSAASGAPTTSAPAPSSSASSGPNQCVICLRVLSCPR------ALRLHYGQHGGE 656
             +    A+ G  + S P P      G  +      +L          A RL   Q   E
Sbjct: 526 PLINAQQASPGCISPSLPPPPLKLLKGSVEAASNAHLLQSKSGTQPHAATRLSLQQPRAE 585

Query: 657 RP----------------------FKCKVCGRAFSTRGNLRAHFV--GHKASPAAR-AQN 691
            P                       + K+  +   T G L+A     G K +PA R    
Sbjct: 586 LPGQPEMKTQLEQDSIIEALLPLSMEAKI--KQEITEGELKAFMTAPGGKKTPAMRKVLY 643

Query: 692 SCPICQKKFTNAVTLQQHVRMHLG 715
            C  C + F  +  L+ HVR HLG
Sbjct: 644 PCRFCNQVFAFSGVLRAHVRSHLG 667



 Score = 31.6 bits (70), Expect = 3.9
 Identities = 39/152 (25%), Positives = 52/152 (34%), Gaps = 13/152 (8%)

Query: 824 EMDSNEKTTQQSSLPPPPPPDSLDQPQPMEQGSSGVLGGKEEGGKPERSSSPASALTPEG 883
           E  SN    Q  S   P     L   QP  +     L G+ E        S   AL P  
Sbjct: 555 EAASNAHLLQSKSGTQPHAATRLSLQQPRAE-----LPGQPEMKTQLEQDSIIEALLPLS 609

Query: 884 -EATSVTLVEELSLQEAM-----RKEPGESSSRKACEVCGQAFPSQAALEEHQKTHPKEG 937
            EA     + E  L+  M     +K P        C  C Q F     L  H ++H    
Sbjct: 610 MEAKIKQEITEGELKAFMTAPGGKKTPAMRKVLYPCRFCNQVFAFSGVLRAHVRSHLGIS 669

Query: 938 PLFTCVFCRQGFLERATLKKHMLLAHHQVQPF 969
           P + C  C     ++A L +H L  H   +P+
Sbjct: 670 P-YQCNICDYIAADKAALIRH-LRTHSGERPY 699



 Score = 30.8 bits (68), Expect = 6.7
 Identities = 21/69 (30%), Positives = 28/69 (40%), Gaps = 3/69 (4%)

Query: 895 SLQEAMRKEPGESSSRKACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERAT 954
           SL   M    GE   +  C VCGQ+F +   +  H K H K+ P           L+R  
Sbjct: 111 SLDRHMLVHSGERPYK--CTVCGQSFTTNGNMHRHMKIHEKD-PNSATATAPPSPLKRRR 167

Query: 955 LKKHMLLAH 963
           L     L+H
Sbjct: 168 LSSKRKLSH 176



 Score = 30.4 bits (67), Expect = 8.7
 Identities = 24/90 (26%), Positives = 34/90 (37%), Gaps = 9/90 (10%)

Query: 913 CEVCGQAFPSQAALEEHQKTHPKEG--------PLFTCVFCRQGFLERATLKKHMLLAHH 964
           C +CG+      AL  H +TH   G          F C  C   F  +     H+L  H 
Sbjct: 755 CRLCGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHL 814

Query: 965 QVQPFAPHGPQNIAALSLVPGCSPSITSTG 994
            V P        +AA  L P  +P+  ++G
Sbjct: 815 HV-PEQDIESYVLAADGLGPAEAPAAEASG 843


>gi|110681708 zinc finger protein 579 [Homo sapiens]
          Length = 562

 Score = 75.5 bits (184), Expect = 2e-13
 Identities = 106/427 (24%), Positives = 147/427 (34%), Gaps = 100/427 (23%)

Query: 624 SSASSGPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKA 683
           + A   P  C  C R+   P  L  H   H G RP  C +C +AF    +L  H  GH  
Sbjct: 37  AGAPRAPLPCPTCGRLFRFPYYLSRHRLSHSGLRPHACPLCPKAFRRPAHLSRHLRGHGP 96

Query: 684 SPAARAQNSCPICQKKFTNAVTLQQHV-RMHLGGQIPNG------GTALPEGGGAAQENG 736
            P  R    C  C + F     L++H+ + H GG++          TA P  G   Q+ G
Sbjct: 97  QPPLR----CAACPRTFPEPAQLRRHLAQEHAGGEVELAIERVAKETAEPSWG--PQDEG 150

Query: 737 SEQSTVSGAGSFPQQ---------------QSQQPSPEEELSEEEEEEDEEEEEDVTDED 781
           SE  T + AG+  ++                   P+   E  E E EE E    ++  E 
Sbjct: 151 SEPPTTAAAGATEEEAVAAWPETWPAGEPSTLAAPTSAAEPRESESEEAEAGAAELRAEL 210

Query: 782 SLAGRGSESGGEKAISVRGD-------SEEASGAEEEVGTVAAAATAGKEMDSNEKTTQQ 834
           +LA    E   EK + ++ D         EA   + E+         G+         Q+
Sbjct: 211 ALAAGRQE---EKQVLLQADWTLLCLRCREAFATKGELKAHPCLRPEGE---------QE 258

Query: 835 SSLPPPPPP------------------------DSLDQP------------------QPM 852
               PPP P                         S D+P                     
Sbjct: 259 GEGGPPPRPKRHQCSICLKAFARPWSLSRHRLVHSTDRPFVCPDCGLAFRLASYLRQHRR 318

Query: 853 EQGSSGVLGGKEEGGKPERSSSPA--SALTPE-GEATSVTLVEE----LSLQEAMRKEPG 905
             G   +L      GK +  +S A  SA  PE GE        E     +  +A    P 
Sbjct: 319 VHGPLSLLAPLPAAGKKDDKASGARNSAKGPEGGEGAECGGASEGGEGQNGGDAAPARPP 378

Query: 906 ESSSRKACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAHHQ 965
               R  C  CG+ F  +A L +H  TH    P F CV C++ F   A L +H  +  H 
Sbjct: 379 AGEPRFWCPECGKGFRRRAHLRQHGVTHSGARP-FQCVRCQREFKRLADLARHAQV--HA 435

Query: 966 VQPFAPH 972
             P APH
Sbjct: 436 GGP-APH 441



 Score = 70.1 bits (170), Expect = 1e-11
 Identities = 110/483 (22%), Positives = 159/483 (32%), Gaps = 88/483 (18%)

Query: 360 GEVMGPLEKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVH 419
           G   G    P     C  C ++F     L  H  SH+G RP+ C +C   F    +L  H
Sbjct: 31  GRGRGGAGAPRAPLPCPTCGRLFRFPYYLSRHRLSHSGLRPHACPLCPKAFRRPAHLSRH 90

Query: 420 FHRHREKYP---HVQMNPHPVPEHLDYVITSSGLPYGMSVPPEKAEEEAATPGGGVERKP 476
              H  + P          P P  L   +        + +  E+  +E A P  G + + 
Sbjct: 91  LRGHGPQPPLRCAACPRTFPEPAQLRRHLAQEHAGGEVELAIERVAKETAEPSWGPQDEG 150

Query: 477 LVASTTALS-ATESLTLLSTSAGTATAPGLPAFNKFVLMKAVEPKNKADENTPPGSEGSA 535
               TTA + ATE   +   +A   T P            A EP+    E     +E  A
Sbjct: 151 SEPPTTAAAGATEEEAV---AAWPETWPAGEPSTLAAPTSAAEPRESESEE----AEAGA 203

Query: 536 ISGVAESSTATRMQLSKLVTSLPSWALLT----NHFKSTGSFPFPYVLEPLGASPSE--- 588
               AE + A   Q  K V     W LL       F + G       L P G    E   
Sbjct: 204 AELRAELALAAGRQEEKQVLLQADWTLLCLRCREAFATKGELKAHPCLRPEGEQEGEGGP 263

Query: 589 --------------------TSKLQQLVEKIDRQGAVAVTSAA-------------SGAP 615
                               +    +LV   DR         A              G  
Sbjct: 264 PPRPKRHQCSICLKAFARPWSLSRHRLVHSTDRPFVCPDCGLAFRLASYLRQHRRVHGPL 323

Query: 616 TTSAPAPSS-----------SASSGPNQCVICLRVLSCPRALRLHYGQHGGE----RP-- 658
           +  AP P++           +++ GP           C  A     GQ+GG+    RP  
Sbjct: 324 SLLAPLPAAGKKDDKASGARNSAKGPEGG----EGAECGGASEGGEGQNGGDAAPARPPA 379

Query: 659 ----FKCKVCGRAFSTRGNLRAHFVGHKASPAARAQNSCPICQKKFTNAVTLQQHVRMHL 714
               F C  CG+ F  R +LR H V H  +   +    C  CQ++F     L +H ++H 
Sbjct: 380 GEPRFWCPECGKGFRRRAHLRQHGVTHSGARPFQ----CVRCQREFKRLADLARHAQVHA 435

Query: 715 GGQIPNGGTALPEGGGAA----QENGSEQSTVSGAGSFPQQQSQQPS----PEEELSEEE 766
           GG  P+     P     A    +     ++ +  A +    Q+Q P+    P   L  E+
Sbjct: 436 GGPAPHPCPRCPRRFSRAYSLLRHQRCHRAELERAAALQALQAQAPTSPPPPPPPLKAEQ 495

Query: 767 EEE 769
           EEE
Sbjct: 496 EEE 498



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 46/163 (28%), Positives = 61/163 (37%), Gaps = 24/163 (14%)

Query: 646 LRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARAQNSCPICQKKFTNAVT 705
           LR H   H G RPF+C  C R F    +L  H   H   P   A + CP C ++F+ A +
Sbjct: 399 LRQHGVTHSGARPFQCVRCQREFKRLADLARHAQVHAGGP---APHPCPRCPRRFSRAYS 455

Query: 706 LQQHVRMH------------LGGQIPNGGTALPEGGGAAQENGSEQSTVSGAGSFPQQ-- 751
           L +H R H            L  Q P      P    A QE       ++     P    
Sbjct: 456 LLRHQRCHRAELERAAALQALQAQAPTSPPPPPPPLKAEQEEEGLPLPLANIKEEPPSPG 515

Query: 752 --QSQQPSPEEELS-----EEEEEEDEEEEEDVTDEDSLAGRG 787
                 P+P   LS      ++    E EEE+V  +  L G G
Sbjct: 516 TPPQSPPAPPVFLSASCFDSQDHSAFEMEEEEVDSKAHLRGLG 558



 Score = 47.4 bits (111), Expect = 7e-05
 Identities = 99/436 (22%), Positives = 131/436 (30%), Gaps = 92/436 (21%)

Query: 33  PQVCAKCCAQFTDPTEFLAHQNACSTDPPVMVIIGGQENPNNSSASSEPRPEGHNNPQVM 92
           P  C  C   F  P     H       PP+             +A     PE     + +
Sbjct: 71  PHACPLCPKAFRRPAHLSRHLRGHGPQPPL-----------RCAACPRTFPEPAQLRRHL 119

Query: 93  DTEHSNPP-----DSGSSVPTDPTWGPERRGEESPGHFLVAATGTAA--------GGGGG 139
             EH+        +  +    +P+WGP+  G E P      AT   A          G  
Sbjct: 120 AQEHAGGEVELAIERVAKETAEPSWGPQDEGSEPPTTAAAGATEEEAVAAWPETWPAGEP 179

Query: 140 LILASPKLGATPLPPESTPAPPPPPPPPPPPGVGSGHLNIPLILEELRVLQQRQIHQMQM 199
             LA+P   A P   ES  A             G+  L   L L   R  +++ + Q   
Sbjct: 180 STLAAPTSAAEPRESESEEAE-----------AGAAELRAELALAAGRQEEKQVLLQADW 228

Query: 200 TEQICRQVLLLGSLGQTVGAPASPSELPGTGTASSTKPLLPLFSPIKPVQTSKTLASSSS 259
           T    R      + G+    P    E  G        P  P     K  Q S  L + + 
Sbjct: 229 TLLCLRCREAFATKGELKAHPCLRPE--GEQEGEGGPPPRP-----KRHQCSICLKAFAR 281

Query: 260 SSSSSSGAETPKQAFFHLYHPLGSQHPFSAGGVG-------------RSHKPTP--APSP 304
             S S            L H   +  PF     G             R H P    AP P
Sbjct: 282 PWSLSR---------HRLVH--STDRPFVCPDCGLAFRLASYLRQHRRVHGPLSLLAPLP 330

Query: 305 ALPGSTDQLIASPHLAFPSTTGLLAAQCLGAARGLEATASPGLLKPKNGSGELSYGEVMG 364
           A  G  D   +    +     G   A+C GA+ G                GE   G    
Sbjct: 331 AA-GKKDDKASGARNSAKGPEGGEGAECGGASEG----------------GEGQNGGDAA 373

Query: 365 PLEKPGG--RHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHR 422
           P   P G  R  C  C K F   + L+ H  +H+G RP++C  C   F    +L  H   
Sbjct: 374 PARPPAGEPRFWCPECGKGFRRRAHLRQHGVTHSGARPFQCVRCQREFKRLADLARHAQV 433

Query: 423 HREKYPHVQMNPHPVP 438
           H          PHP P
Sbjct: 434 HAG-----GPAPHPCP 444


>gi|172072684 PR domain containing 1, with ZNF domain isoform 1
           [Homo sapiens]
          Length = 825

 Score = 75.1 bits (183), Expect = 3e-13
 Identities = 92/365 (25%), Positives = 140/365 (38%), Gaps = 76/365 (20%)

Query: 77  ASSEPRPEGHNNPQVM---DTEHSNPPDSGSSVPTDPTWGPERRGEESPGHFLVAATGTA 133
           +S+ P P   ++P       + HS+P ++ S V      GP  +       +L A+ GT 
Sbjct: 331 SSTTPSPSARSSPDQSLKSSSPHSSPGNTVSPV------GPGSQEHRDSYAYLNASYGTE 384

Query: 134 AGGGGGLILASPKLGATP-LPPESTPAPPPPPPP--PPPPGVGSGHLNIPLILEELRVLQ 190
             G      + P     P LPP   P+     P    PP G+    L+         V  
Sbjct: 385 GLG------SYPGYAPLPHLPPAFIPSYNAHYPKFLLPPYGMNCNGLSA--------VSS 430

Query: 191 QRQIHQMQMTEQIC---RQVLLLGSLGQTVGAPAS-PSELPGTGTASSTKPLLPLFSPIK 246
              I+   +  ++C     +L  GSL   +  P S PS LP  G     +P  P      
Sbjct: 431 MNGINNFGLFPRLCPVYSNLLGGGSLPHPMLNPTSLPSSLPSDGARRLLQPEHP------ 484

Query: 247 PVQTSKTLASSSSSSSSSSGAETPKQAFFHLYHPLGSQHPFSAGGVGRSHKPTPAPSPAL 306
                + L  +  S+ S +GA                    +A    ++  PT     A 
Sbjct: 485 ----REVLVPAPHSAFSFTGA--------------------AASMKDKACSPTSGSPTAG 520

Query: 307 PGSTDQLIASPHLAFPSTTGLLAAQCLGAARGLEATASPGLLKPKNGSGELSYGEVMGPL 366
             +T + +  P     +T+  +AA     A  L           KN      Y  +  PL
Sbjct: 521 TAATAEHVVQPK----ATSAAMAAPSSDEAMNLI----------KNKRNMTGYKTLPYPL 566

Query: 367 EKPGGR--HKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHR 424
           +K  G+  ++C  CAK FG  S L++HLR H+GERP+KC  C   FT   +L+ H+  H 
Sbjct: 567 KKQNGKIKYECNVCAKTFGQLSNLKVHLRVHSGERPFKCQTCNKGFTQLAHLQKHYLVHT 626

Query: 425 EKYPH 429
            + PH
Sbjct: 627 GEKPH 631



 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 26/84 (30%), Positives = 46/84 (54%), Gaps = 4/84 (4%)

Query: 632 QCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARAQN 691
           +C +C +       L++H   H GERPFKC+ C + F+   +L+ H++ H         +
Sbjct: 576 ECNVCAKTFGQLSNLKVHLRVHSGERPFKCQTCNKGFTQLAHLQKHYLVH----TGEKPH 631

Query: 692 SCPICQKKFTNAVTLQQHVRMHLG 715
            C +C K+F++   L+ H+R+H G
Sbjct: 632 ECQVCHKRFSSTSNLKTHLRLHSG 655



 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 33/75 (44%), Positives = 43/75 (57%), Gaps = 3/75 (4%)

Query: 367 EKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREK 426
           EKP   H+C+ C K F S S L+ HLR H+GE+PY+C VC  +FT   +LK+H   H  +
Sbjct: 628 EKP---HECQVCHKRFSSTSNLKTHLRLHSGEKPYQCKVCPAKFTQFVHLKLHKRLHTRE 684

Query: 427 YPHVQMNPHPVPEHL 441
            PH     H    HL
Sbjct: 685 RPHKCSQCHKNYIHL 699



 Score = 58.2 bits (139), Expect = 4e-08
 Identities = 29/84 (34%), Positives = 43/84 (51%), Gaps = 4/84 (4%)

Query: 630 PNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARA 689
           P +C  C +  +    L+ HY  H GE+P +C+VC + FS+  NL+ H   H    +   
Sbjct: 602 PFKCQTCNKGFTQLAHLQKHYLVHTGEKPHECQVCHKRFSSTSNLKTHLRLH----SGEK 657

Query: 690 QNSCPICQKKFTNAVTLQQHVRMH 713
              C +C  KFT  V L+ H R+H
Sbjct: 658 PYQCKVCPAKFTQFVHLKLHKRLH 681



 Score = 50.4 bits (119), Expect = 8e-06
 Identities = 23/82 (28%), Positives = 41/82 (50%), Gaps = 4/82 (4%)

Query: 630 PNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARA 689
           P++C +C +  S    L+ H   H GE+P++CKVC   F+   +L+     HK       
Sbjct: 630 PHECQVCHKRFSSTSNLKTHLRLHSGEKPYQCKVCPAKFTQFVHLKL----HKRLHTRER 685

Query: 690 QNSCPICQKKFTNAVTLQQHVR 711
            + C  C K + +  +L+ H++
Sbjct: 686 PHKCSQCHKNYIHLCSLKVHLK 707



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 21/53 (39%), Positives = 30/53 (56%), Gaps = 3/53 (5%)

Query: 367 EKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVH 419
           EKP   ++C+ C   F     L++H R HT ERP+KC+ C   +    +LKVH
Sbjct: 656 EKP---YQCKVCPAKFTQFVHLKLHKRLHTRERPHKCSQCHKNYIHLCSLKVH 705



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 30/121 (24%), Positives = 48/121 (39%), Gaps = 18/121 (14%)

Query: 609 SAASGAPTTSA---------PAPSSSASSGPNQ-----CVICLRVLSCPRALRLHYGQHG 654
           S  SG+PT            P  +S+A + P+       +   R ++  + L     +  
Sbjct: 511 SPTSGSPTAGTAATAEHVVQPKATSAAMAAPSSDEAMNLIKNKRNMTGYKTLPYPLKKQN 570

Query: 655 GERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARAQNSCPICQKKFTNAVTLQQHVRMHL 714
           G+  ++C VC + F    NL+ H   H      +    C  C K FT    LQ+H  +H 
Sbjct: 571 GKIKYECNVCAKTFGQLSNLKVHLRVHSGERPFK----CQTCNKGFTQLAHLQKHYLVHT 626

Query: 715 G 715
           G
Sbjct: 627 G 627



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 22/67 (32%), Positives = 36/67 (53%), Gaps = 3/67 (4%)

Query: 895 SLQEAMRKEPGESSSRKACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERAT 954
           +L   ++K+ G+   +  C VC + F   + L+ H + H  E P F C  C +GF + A 
Sbjct: 561 TLPYPLKKQNGKI--KYECNVCAKTFGQLSNLKVHLRVHSGERP-FKCQTCNKGFTQLAH 617

Query: 955 LKKHMLL 961
           L+KH L+
Sbjct: 618 LQKHYLV 624



 Score = 35.8 bits (81), Expect = 0.21
 Identities = 22/75 (29%), Positives = 35/75 (46%), Gaps = 4/75 (5%)

Query: 895 SLQEAMRKEPGESSSRKACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERAT 954
           +L+  +R   GE   +  C+ C + F   A L++H   H  E P   C  C + F   + 
Sbjct: 589 NLKVHLRVHSGERPFK--CQTCNKGFTQLAHLQKHYLVHTGEKP-HECQVCHKRFSSTSN 645

Query: 955 LKKHMLLAHHQVQPF 969
           LK H+ L H   +P+
Sbjct: 646 LKTHLRL-HSGEKPY 659



 Score = 35.8 bits (81), Expect = 0.21
 Identities = 19/58 (32%), Positives = 28/58 (48%)

Query: 630 PNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAA 687
           P QC +C    +    L+LH   H  ERP KC  C + +    +L+ H  G+ A+  A
Sbjct: 658 PYQCKVCPAKFTQFVHLKLHKRLHTRERPHKCSQCHKNYIHLCSLKVHLKGNCAAAPA 715



 Score = 33.1 bits (74), Expect = 1.3
 Identities = 18/65 (27%), Positives = 32/65 (49%), Gaps = 3/65 (4%)

Query: 895 SLQEAMRKEPGESSSRKACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERAT 954
           +L+  +R   GE   +  C+VC   F     L+ H++ H +E P   C  C + ++   +
Sbjct: 645 NLKTHLRLHSGEKPYQ--CKVCPAKFTQFVHLKLHKRLHTRERP-HKCSQCHKNYIHLCS 701

Query: 955 LKKHM 959
           LK H+
Sbjct: 702 LKVHL 706


>gi|33946274 PR domain containing 1, with ZNF domain isoform 2 [Homo
           sapiens]
          Length = 691

 Score = 75.1 bits (183), Expect = 3e-13
 Identities = 92/365 (25%), Positives = 140/365 (38%), Gaps = 76/365 (20%)

Query: 77  ASSEPRPEGHNNPQVM---DTEHSNPPDSGSSVPTDPTWGPERRGEESPGHFLVAATGTA 133
           +S+ P P   ++P       + HS+P ++ S V      GP  +       +L A+ GT 
Sbjct: 197 SSTTPSPSARSSPDQSLKSSSPHSSPGNTVSPV------GPGSQEHRDSYAYLNASYGTE 250

Query: 134 AGGGGGLILASPKLGATP-LPPESTPAPPPPPPP--PPPPGVGSGHLNIPLILEELRVLQ 190
             G      + P     P LPP   P+     P    PP G+    L+         V  
Sbjct: 251 GLG------SYPGYAPLPHLPPAFIPSYNAHYPKFLLPPYGMNCNGLSA--------VSS 296

Query: 191 QRQIHQMQMTEQIC---RQVLLLGSLGQTVGAPAS-PSELPGTGTASSTKPLLPLFSPIK 246
              I+   +  ++C     +L  GSL   +  P S PS LP  G     +P  P      
Sbjct: 297 MNGINNFGLFPRLCPVYSNLLGGGSLPHPMLNPTSLPSSLPSDGARRLLQPEHP------ 350

Query: 247 PVQTSKTLASSSSSSSSSSGAETPKQAFFHLYHPLGSQHPFSAGGVGRSHKPTPAPSPAL 306
                + L  +  S+ S +GA                    +A    ++  PT     A 
Sbjct: 351 ----REVLVPAPHSAFSFTGA--------------------AASMKDKACSPTSGSPTAG 386

Query: 307 PGSTDQLIASPHLAFPSTTGLLAAQCLGAARGLEATASPGLLKPKNGSGELSYGEVMGPL 366
             +T + +  P     +T+  +AA     A  L           KN      Y  +  PL
Sbjct: 387 TAATAEHVVQPK----ATSAAMAAPSSDEAMNLI----------KNKRNMTGYKTLPYPL 432

Query: 367 EKPGGR--HKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHR 424
           +K  G+  ++C  CAK FG  S L++HLR H+GERP+KC  C   FT   +L+ H+  H 
Sbjct: 433 KKQNGKIKYECNVCAKTFGQLSNLKVHLRVHSGERPFKCQTCNKGFTQLAHLQKHYLVHT 492

Query: 425 EKYPH 429
            + PH
Sbjct: 493 GEKPH 497



 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 26/84 (30%), Positives = 46/84 (54%), Gaps = 4/84 (4%)

Query: 632 QCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARAQN 691
           +C +C +       L++H   H GERPFKC+ C + F+   +L+ H++ H         +
Sbjct: 442 ECNVCAKTFGQLSNLKVHLRVHSGERPFKCQTCNKGFTQLAHLQKHYLVH----TGEKPH 497

Query: 692 SCPICQKKFTNAVTLQQHVRMHLG 715
            C +C K+F++   L+ H+R+H G
Sbjct: 498 ECQVCHKRFSSTSNLKTHLRLHSG 521



 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 33/75 (44%), Positives = 43/75 (57%), Gaps = 3/75 (4%)

Query: 367 EKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREK 426
           EKP   H+C+ C K F S S L+ HLR H+GE+PY+C VC  +FT   +LK+H   H  +
Sbjct: 494 EKP---HECQVCHKRFSSTSNLKTHLRLHSGEKPYQCKVCPAKFTQFVHLKLHKRLHTRE 550

Query: 427 YPHVQMNPHPVPEHL 441
            PH     H    HL
Sbjct: 551 RPHKCSQCHKNYIHL 565



 Score = 58.2 bits (139), Expect = 4e-08
 Identities = 29/84 (34%), Positives = 43/84 (51%), Gaps = 4/84 (4%)

Query: 630 PNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARA 689
           P +C  C +  +    L+ HY  H GE+P +C+VC + FS+  NL+ H   H    +   
Sbjct: 468 PFKCQTCNKGFTQLAHLQKHYLVHTGEKPHECQVCHKRFSSTSNLKTHLRLH----SGEK 523

Query: 690 QNSCPICQKKFTNAVTLQQHVRMH 713
              C +C  KFT  V L+ H R+H
Sbjct: 524 PYQCKVCPAKFTQFVHLKLHKRLH 547



 Score = 50.4 bits (119), Expect = 8e-06
 Identities = 23/82 (28%), Positives = 41/82 (50%), Gaps = 4/82 (4%)

Query: 630 PNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARA 689
           P++C +C +  S    L+ H   H GE+P++CKVC   F+   +L+     HK       
Sbjct: 496 PHECQVCHKRFSSTSNLKTHLRLHSGEKPYQCKVCPAKFTQFVHLKL----HKRLHTRER 551

Query: 690 QNSCPICQKKFTNAVTLQQHVR 711
            + C  C K + +  +L+ H++
Sbjct: 552 PHKCSQCHKNYIHLCSLKVHLK 573



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 21/53 (39%), Positives = 30/53 (56%), Gaps = 3/53 (5%)

Query: 367 EKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVH 419
           EKP   ++C+ C   F     L++H R HT ERP+KC+ C   +    +LKVH
Sbjct: 522 EKP---YQCKVCPAKFTQFVHLKLHKRLHTRERPHKCSQCHKNYIHLCSLKVH 571



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 30/121 (24%), Positives = 48/121 (39%), Gaps = 18/121 (14%)

Query: 609 SAASGAPTTSA---------PAPSSSASSGPNQ-----CVICLRVLSCPRALRLHYGQHG 654
           S  SG+PT            P  +S+A + P+       +   R ++  + L     +  
Sbjct: 377 SPTSGSPTAGTAATAEHVVQPKATSAAMAAPSSDEAMNLIKNKRNMTGYKTLPYPLKKQN 436

Query: 655 GERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARAQNSCPICQKKFTNAVTLQQHVRMHL 714
           G+  ++C VC + F    NL+ H   H      +    C  C K FT    LQ+H  +H 
Sbjct: 437 GKIKYECNVCAKTFGQLSNLKVHLRVHSGERPFK----CQTCNKGFTQLAHLQKHYLVHT 492

Query: 715 G 715
           G
Sbjct: 493 G 493



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 22/67 (32%), Positives = 36/67 (53%), Gaps = 3/67 (4%)

Query: 895 SLQEAMRKEPGESSSRKACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERAT 954
           +L   ++K+ G+   +  C VC + F   + L+ H + H  E P F C  C +GF + A 
Sbjct: 427 TLPYPLKKQNGKI--KYECNVCAKTFGQLSNLKVHLRVHSGERP-FKCQTCNKGFTQLAH 483

Query: 955 LKKHMLL 961
           L+KH L+
Sbjct: 484 LQKHYLV 490



 Score = 35.8 bits (81), Expect = 0.21
 Identities = 22/75 (29%), Positives = 35/75 (46%), Gaps = 4/75 (5%)

Query: 895 SLQEAMRKEPGESSSRKACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERAT 954
           +L+  +R   GE   +  C+ C + F   A L++H   H  E P   C  C + F   + 
Sbjct: 455 NLKVHLRVHSGERPFK--CQTCNKGFTQLAHLQKHYLVHTGEKP-HECQVCHKRFSSTSN 511

Query: 955 LKKHMLLAHHQVQPF 969
           LK H+ L H   +P+
Sbjct: 512 LKTHLRL-HSGEKPY 525



 Score = 35.8 bits (81), Expect = 0.21
 Identities = 19/58 (32%), Positives = 28/58 (48%)

Query: 630 PNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAA 687
           P QC +C    +    L+LH   H  ERP KC  C + +    +L+ H  G+ A+  A
Sbjct: 524 PYQCKVCPAKFTQFVHLKLHKRLHTRERPHKCSQCHKNYIHLCSLKVHLKGNCAAAPA 581



 Score = 33.1 bits (74), Expect = 1.3
 Identities = 18/65 (27%), Positives = 32/65 (49%), Gaps = 3/65 (4%)

Query: 895 SLQEAMRKEPGESSSRKACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERAT 954
           +L+  +R   GE   +  C+VC   F     L+ H++ H +E P   C  C + ++   +
Sbjct: 511 NLKTHLRLHSGEKPYQ--CKVCPAKFTQFVHLKLHKRLHTRERP-HKCSQCHKNYIHLCS 567

Query: 955 LKKHM 959
           LK H+
Sbjct: 568 LKVHL 572


>gi|156416026 zinc finger protein 219 [Homo sapiens]
          Length = 722

 Score = 75.1 bits (183), Expect = 3e-13
 Identities = 89/363 (24%), Positives = 136/363 (37%), Gaps = 36/363 (9%)

Query: 145 PKLGATPLPPESTPAPPPPPPPPPPPGVGSGHLNIPLILEELRVLQQRQIHQMQMTEQIC 204
           P+  ATP P  + P  PP PP       G        +   +R  +    H   +  +  
Sbjct: 252 PEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCF 311

Query: 205 RQVLLLGSLGQTVGAPASPSELPGTGTASSTKPLLPLFSPI--KPVQTSKTLASSSSSSS 262
           ++   L +  +   +   P   PG  +  +  P  P    +  +P+  +  LA + + + 
Sbjct: 312 KEPWFLKNHMKVHASKLGPLRAPGPASGPARAPQPPDLGLLAYEPLGPALLLAPAPTPAE 371

Query: 263 SSSGAETPKQAFFHLYHPLGSQHPFSAG---GVGRSH---KPTPAPSPAL--------PG 308
                  P     +L    G   P   G   G GRS    +P  +  PA         P 
Sbjct: 372 RRE----PPSLLGYLSLRAGEGRPNGEGAEPGPGRSFGGFRPLSSALPARARRHRAEEPE 427

Query: 309 STDQLIASPHLAFPS--TTGLLAAQCLGAARGLEATASPGLLKPKNGSGELSYGEVMGPL 366
             ++++ +    +    + G LA+       G   +AS    + ++ + +   G ++G  
Sbjct: 428 EEEEVVEAEEETWARGRSLGSLASLHPRPGEGPGHSASAAGAQARSTATQEENGLLVGGT 487

Query: 367 EKPGGR----HKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHR 422
              GGR      C FC K F S   L++HLR HTGERPYKC  C    T  G+LK H  R
Sbjct: 488 RPEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQR 547

Query: 423 HREKYPHVQMNPHPVPEHLDYVITSSGLPYGMSVPPEKAE--EEAATP-------GGGVE 473
           H  +       P P PE        S    G    P+ A   E A++P       G G  
Sbjct: 548 HHRE-QRSGAGPGPPPEPPPPSQRGSAPQSGAKPSPQPATWVEGASSPRPPSSGAGPGSR 606

Query: 474 RKP 476
           RKP
Sbjct: 607 RKP 609



 Score = 68.2 bits (165), Expect = 4e-11
 Identities = 86/334 (25%), Positives = 128/334 (38%), Gaps = 65/334 (19%)

Query: 659 FKCKVCGRAFSTRGNLRAHFVGHKASPAARAQNSCPICQKKFTNAVTLQQHVRMH----- 713
           F+C+VCG++F+    L+ H   HKAS      ++CP+C + F     L+ H+++H     
Sbjct: 274 FRCQVCGQSFTQSWFLKGHMRKHKAS----FDHACPVCGRCFKEPWFLKNHMKVHASKLG 329

Query: 714 -LGGQIPNGGTAL----PEGGGAAQENGSEQSTVSGAGSFPQQQSQQPSPEEELSEEEEE 768
            L    P  G A     P+ G  A E       ++ A + P ++ + PS    LS    E
Sbjct: 330 PLRAPGPASGPARAPQPPDLGLLAYEPLGPALLLAPAPT-PAERREPPSLLGYLSLRAGE 388

Query: 769 EDEEEEEDVTDEDSLAGRGSESGGEKAISV-------RGDSEEASGAEEEVGTVAAAATA 821
                      E +  G G   GG + +S        R  +EE    EE V         
Sbjct: 389 GRPN------GEGAEPGPGRSFGGFRPLSSALPARARRHRAEEPEEEEEVVEAEEETWAR 442

Query: 822 GKEMDSNEKTTQQSSLPPPPPPDSLDQPQPMEQGSSGVLGGKEEGGKPERSSSPASALTP 881
           G+ + S       +SL P P                        G  P  S+S A A   
Sbjct: 443 GRSLGS------LASLHPRP------------------------GEGPGHSASAAGA--- 469

Query: 882 EGEATSVTLVEELSLQEA-MRKEPGESSSRKACEVCGQAFPSQAALEEHQKTHPKEGPLF 940
             +A S    EE  L     R E G  ++ K C  CG++F S   L+ H + H  E P +
Sbjct: 470 --QARSTATQEENGLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERP-Y 526

Query: 941 TCVFCRQGFLERATLKKHMLLAHHQVQPFAPHGP 974
            C  C     +  +LK H+   H + +  A  GP
Sbjct: 527 KCPHCDYAGTQSGSLKYHLQRHHREQRSGAGPGP 560



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 85/337 (25%), Positives = 117/337 (34%), Gaps = 70/337 (20%)

Query: 655 GERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARAQNSCPICQKKFTNAVTLQQHVRMHL 714
           GER F C VCG+ F     L  H   H  + A +    CP C  +      L+ H+R H 
Sbjct: 53  GERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQ----CPHCGHRAAQRALLRSHLRTHQ 108

Query: 715 GGQIPNGGTA-----LPEGG-------GAAQENGSEQSTVSGAG-SFPQQQSQQ----PS 757
             + P    A     L E         G A+ +G  Q+T +  G + PQ  S      P 
Sbjct: 109 PER-PRSPAARLLLELEERALLREARLGRARSSGGMQATPATEGLARPQAPSSSAFRCPY 167

Query: 758 PEEELSEEEEEEDEEEEEDVTDEDSLAGRGSESGGEKAISVRGDSEEASGAEEEVGTVAA 817
            + +     E E          +  L   GS    E    +   S  A GA E      +
Sbjct: 168 CKGKFRTSAERERHLHILHRPWKCGLCSFGSSQEEE----LLHHSLTAHGAPERPLAATS 223

Query: 818 AATAGKEMDSNEKTTQQSSLPPPPPPDSLDQPQPMEQGSSGVLGGKEEGGKPERSSSPAS 877
           AA   +          Q   PP P P S+ QP+P  +              PER ++P  
Sbjct: 224 AAPPPQP---------QPQPPPQPEPRSVPQPEPEPE--------------PEREATPTP 260

Query: 878 ALTPEGEATSVTLVEELSLQEAMRKEPGESSSRKACEVCGQAFPSQAALEEHQKTHPKEG 937
           A                    A  + P     R  C+VCGQ+F     L+ H + H K  
Sbjct: 261 A------------------PAAPEEPPAPPEFR--CQVCGQSFTQSWFLKGHMRKH-KAS 299

Query: 938 PLFTCVFCRQGFLERATLKKHMLLAHHQVQPFAPHGP 974
               C  C + F E   LK HM +   ++ P    GP
Sbjct: 300 FDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPGP 336



 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 103/492 (20%), Positives = 146/492 (29%), Gaps = 67/492 (13%)

Query: 374 KCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKY-----P 428
           +C+ C + F     L+ H+R H     + C VCG  F     LK H   H  K      P
Sbjct: 275 RCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAP 334

Query: 429 HVQMNPHPVPEHLDYVITSSGLPYGMSVPPEKAEEEAATPGGGVERKPLVASTTALSATE 488
                P   P+  D      GL     + P      A TP    E  P +    +L A E
Sbjct: 335 GPASGPARAPQPPDL-----GLLAYEPLGPALLLAPAPTPAERRE-PPSLLGYLSLRAGE 388

Query: 489 SLTLLSTSAGTATAPGLPAFNKFVLMKAVEPKNKADENTPPGSEGSAISGVAESSTATRM 548
                    G    PG  +F  F  + +  P            E   +    E + A   
Sbjct: 389 GRP---NGEGAEPGPGR-SFGGFRPLSSALPARARRHRAEEPEEEEEVVEAEEETWARGR 444

Query: 549 QLSKLVTSLPSWALLTNHFKSTGSFPFPYVLEPLGASPSETSKLQQLVEKIDRQGAVAVT 608
            L  L +  P       H  S             GA    T+  ++              
Sbjct: 445 SLGSLASLHPRPGEGPGHSASAA-----------GAQARSTATQEE-------------- 479

Query: 609 SAASGAPTTSAPAPSSSASSGPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAF 668
                        P     +    C  C +       L++H   H GERP+KC  C  A 
Sbjct: 480 ----NGLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAG 535

Query: 669 STRGNLRAHFVGHKASPAARAQNSCPICQKKFTNAVTLQQHVRMHLGGQIPNGGTALPEG 728
           +  G+L+ H   H     + A    P             +       G  P  G A P  
Sbjct: 536 TQSGSLKYHLQRHHREQRSGAGPGPP------------PEPPPPSQRGSAPQSG-AKPSP 582

Query: 729 GGAAQENGSEQSTVSGAGSFPQQQSQQPSPEEELSEEEEEEDEEEEEDVTDEDSLAGRGS 788
             A    G+       +G+ P  + +  SP   L      E E       D    AG G 
Sbjct: 583 QPATWVEGASSPRPPSSGAGPGSRRKPASPGRTLRNGRGGEAEP-----LDLSLRAGPGG 637

Query: 789 ESGGEKAISVRGDSEEASGAEEEVGTVAAAATAGKEMDSNEKTTQQSSLPPP--PPPDSL 846
           E+G   A+        A+GA E    +A          +  +   Q+   PP    P   
Sbjct: 638 EAGPGGALHRCLFCPFATGAPE---LMALHLQVHHSRRARGRRPPQADASPPYARVPSGE 694

Query: 847 DQPQPMEQGSSG 858
             P P ++G  G
Sbjct: 695 TPPSPSQEGEEG 706



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 27/80 (33%), Positives = 39/80 (48%), Gaps = 1/80 (1%)

Query: 350 PKNGSGELSYGEVMGPLEKPGGRH-KCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGN 408
           P   +G L  G V     + G R   C  C K F  +S L +HLR+H G + ++C  CG+
Sbjct: 33  PAVSAGSLGMGAVSWSESRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGH 92

Query: 409 RFTTRGNLKVHFHRHREKYP 428
           R   R  L+ H   H+ + P
Sbjct: 93  RAAQRALLRSHLRTHQPERP 112



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 104/447 (23%), Positives = 146/447 (32%), Gaps = 57/447 (12%)

Query: 394 SHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPHVQ--MNPHPVPEHLDYVITSSGLP 451
           S  GER + C VCG RF     L +H   H    P  Q    PH         +  S L 
Sbjct: 50  SRAGERRFPCPVCGKRFRFNSILALHLRAH----PGAQAFQCPHCGHRAAQRALLRSHL- 104

Query: 452 YGMSVPPEKAEEEAATPGGGVERKPLVASTTALSATESLTLLSTSAGTATA-PGLPAFNK 510
              +  PE+    AA     +E + L+       A  S  + +T A    A P  P+ + 
Sbjct: 105 --RTHQPERPRSPAARLLLELEERALLREARLGRARSSGGMQATPATEGLARPQAPSSSA 162

Query: 511 FVLMKAVEPKNKADENTPPGSEGSAI-------SGVAESSTATRMQLSKLVTSLPSWALL 563
           F       P  K    T    E            G+    ++   +L  L  SL +    
Sbjct: 163 FRC-----PYCKGKFRTSAERERHLHILHRPWKCGLCSFGSSQEEEL--LHHSLTAHGAP 215

Query: 564 TNHFKSTGSFPFPYVLEPLGASPSETSKLQQLVEKIDRQGAVAVTSAASGAPTTSAPAPS 623
                +T + P P         P   S  Q   E    + A          PT +  AP 
Sbjct: 216 ERPLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEPEREAT---------PTPAPAAPE 266

Query: 624 SSASSGPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGH-- 681
              +    +C +C +  +    L+ H  +H       C VCGR F     L+ H   H  
Sbjct: 267 EPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHAS 326

Query: 682 ---------KASPAARAQNSCP---ICQKKFTNAVTLQQHVRMHLGGQIPN--GGTALPE 727
                     AS  ARA        +  +    A+ L          + P+  G  +L  
Sbjct: 327 KLGPLRAPGPASGPARAPQPPDLGLLAYEPLGPALLLAPAPTPAERREPPSLLGYLSLRA 386

Query: 728 GGGAAQENGSEQSTVSGAGSFPQQQSQQPSPEEELSEEEEEEDEEEEEDVTDEDSLAGRG 787
           G G     G+E       G F    S  P+          EE EEEEE V  E+    RG
Sbjct: 387 GEGRPNGEGAEPGPGRSFGGFRPLSSALPA---RARRHRAEEPEEEEEVVEAEEETWARG 443

Query: 788 SESGGEKAISVR-----GDSEEASGAE 809
              G   ++  R     G S  A+GA+
Sbjct: 444 RSLGSLASLHPRPGEGPGHSASAAGAQ 470



 Score = 36.6 bits (83), Expect = 0.12
 Identities = 42/152 (27%), Positives = 56/152 (36%), Gaps = 27/152 (17%)

Query: 868  KPERSSSPASALTPE------------GEATSVTLVEELSLQEAMRKEPGESSSRKACEV 915
            +PER  SPA+ L  E            G A S   ++     E + +    SSS   C  
Sbjct: 108  QPERPRSPAARLLLELEERALLREARLGRARSSGGMQATPATEGLARPQAPSSSAFRCPY 167

Query: 916  CGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAHHQVQPFAPHGPQ 975
            C   F + A  E H   H    P + C  C  G  +   L  H L AH      AP  P 
Sbjct: 168  CKGKFRTSAERERH--LHILHRP-WKCGLCSFGSSQEEELLHHSLTAHG-----APERP- 218

Query: 976  NIAALSLVPGCSPSITSTGLSPFPRKDDPTIP 1007
             +AA S  P   P        P P+ +  ++P
Sbjct: 219  -LAATSAAPPPQPQ-----PQPPPQPEPRSVP 244



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 43/134 (32%), Positives = 53/134 (39%), Gaps = 16/134 (11%)

Query: 278 YHPLGSQHPFSAGGVGRSHKPTPAPSPALPGSTDQLIASPHLAFPSTTGLLAAQ----CL 333
           YH L   H     G G    P P P P+  GS  Q  A P    P+T    A+       
Sbjct: 543 YH-LQRHHREQRSGAGPGPPPEPPP-PSQRGSAPQSGAKPSPQ-PATWVEGASSPRPPSS 599

Query: 334 GAARGLEAT-ASPGLLKPKNGSG------ELSYGEVMGPLEKPGGR-HKCRFCAKVFGSD 385
           GA  G     ASPG    +NG G      +LS     G    PGG  H+C FC    G+ 
Sbjct: 600 GAGPGSRRKPASPGRTL-RNGRGGEAEPLDLSLRAGPGGEAGPGGALHRCLFCPFATGAP 658

Query: 386 SALQIHLRSHTGER 399
             + +HL+ H   R
Sbjct: 659 ELMALHLQVHHSRR 672


>gi|156415998 zinc finger protein 219 [Homo sapiens]
          Length = 722

 Score = 75.1 bits (183), Expect = 3e-13
 Identities = 89/363 (24%), Positives = 136/363 (37%), Gaps = 36/363 (9%)

Query: 145 PKLGATPLPPESTPAPPPPPPPPPPPGVGSGHLNIPLILEELRVLQQRQIHQMQMTEQIC 204
           P+  ATP P  + P  PP PP       G        +   +R  +    H   +  +  
Sbjct: 252 PEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCF 311

Query: 205 RQVLLLGSLGQTVGAPASPSELPGTGTASSTKPLLPLFSPI--KPVQTSKTLASSSSSSS 262
           ++   L +  +   +   P   PG  +  +  P  P    +  +P+  +  LA + + + 
Sbjct: 312 KEPWFLKNHMKVHASKLGPLRAPGPASGPARAPQPPDLGLLAYEPLGPALLLAPAPTPAE 371

Query: 263 SSSGAETPKQAFFHLYHPLGSQHPFSAG---GVGRSH---KPTPAPSPAL--------PG 308
                  P     +L    G   P   G   G GRS    +P  +  PA         P 
Sbjct: 372 RRE----PPSLLGYLSLRAGEGRPNGEGAEPGPGRSFGGFRPLSSALPARARRHRAEEPE 427

Query: 309 STDQLIASPHLAFPS--TTGLLAAQCLGAARGLEATASPGLLKPKNGSGELSYGEVMGPL 366
             ++++ +    +    + G LA+       G   +AS    + ++ + +   G ++G  
Sbjct: 428 EEEEVVEAEEETWARGRSLGSLASLHPRPGEGPGHSASAAGAQARSTATQEENGLLVGGT 487

Query: 367 EKPGGR----HKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHR 422
              GGR      C FC K F S   L++HLR HTGERPYKC  C    T  G+LK H  R
Sbjct: 488 RPEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQR 547

Query: 423 HREKYPHVQMNPHPVPEHLDYVITSSGLPYGMSVPPEKAE--EEAATP-------GGGVE 473
           H  +       P P PE        S    G    P+ A   E A++P       G G  
Sbjct: 548 HHRE-QRSGAGPGPPPEPPPPSQRGSAPQSGAKPSPQPATWVEGASSPRPPSSGAGPGSR 606

Query: 474 RKP 476
           RKP
Sbjct: 607 RKP 609



 Score = 68.2 bits (165), Expect = 4e-11
 Identities = 86/334 (25%), Positives = 128/334 (38%), Gaps = 65/334 (19%)

Query: 659 FKCKVCGRAFSTRGNLRAHFVGHKASPAARAQNSCPICQKKFTNAVTLQQHVRMH----- 713
           F+C+VCG++F+    L+ H   HKAS      ++CP+C + F     L+ H+++H     
Sbjct: 274 FRCQVCGQSFTQSWFLKGHMRKHKAS----FDHACPVCGRCFKEPWFLKNHMKVHASKLG 329

Query: 714 -LGGQIPNGGTAL----PEGGGAAQENGSEQSTVSGAGSFPQQQSQQPSPEEELSEEEEE 768
            L    P  G A     P+ G  A E       ++ A + P ++ + PS    LS    E
Sbjct: 330 PLRAPGPASGPARAPQPPDLGLLAYEPLGPALLLAPAPT-PAERREPPSLLGYLSLRAGE 388

Query: 769 EDEEEEEDVTDEDSLAGRGSESGGEKAISV-------RGDSEEASGAEEEVGTVAAAATA 821
                      E +  G G   GG + +S        R  +EE    EE V         
Sbjct: 389 GRPN------GEGAEPGPGRSFGGFRPLSSALPARARRHRAEEPEEEEEVVEAEEETWAR 442

Query: 822 GKEMDSNEKTTQQSSLPPPPPPDSLDQPQPMEQGSSGVLGGKEEGGKPERSSSPASALTP 881
           G+ + S       +SL P P                        G  P  S+S A A   
Sbjct: 443 GRSLGS------LASLHPRP------------------------GEGPGHSASAAGA--- 469

Query: 882 EGEATSVTLVEELSLQEA-MRKEPGESSSRKACEVCGQAFPSQAALEEHQKTHPKEGPLF 940
             +A S    EE  L     R E G  ++ K C  CG++F S   L+ H + H  E P +
Sbjct: 470 --QARSTATQEENGLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERP-Y 526

Query: 941 TCVFCRQGFLERATLKKHMLLAHHQVQPFAPHGP 974
            C  C     +  +LK H+   H + +  A  GP
Sbjct: 527 KCPHCDYAGTQSGSLKYHLQRHHREQRSGAGPGP 560



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 85/337 (25%), Positives = 117/337 (34%), Gaps = 70/337 (20%)

Query: 655 GERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARAQNSCPICQKKFTNAVTLQQHVRMHL 714
           GER F C VCG+ F     L  H   H  + A +    CP C  +      L+ H+R H 
Sbjct: 53  GERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQ----CPHCGHRAAQRALLRSHLRTHQ 108

Query: 715 GGQIPNGGTA-----LPEGG-------GAAQENGSEQSTVSGAG-SFPQQQSQQ----PS 757
             + P    A     L E         G A+ +G  Q+T +  G + PQ  S      P 
Sbjct: 109 PER-PRSPAARLLLELEERALLREARLGRARSSGGMQATPATEGLARPQAPSSSAFRCPY 167

Query: 758 PEEELSEEEEEEDEEEEEDVTDEDSLAGRGSESGGEKAISVRGDSEEASGAEEEVGTVAA 817
            + +     E E          +  L   GS    E    +   S  A GA E      +
Sbjct: 168 CKGKFRTSAERERHLHILHRPWKCGLCSFGSSQEEE----LLHHSLTAHGAPERPLAATS 223

Query: 818 AATAGKEMDSNEKTTQQSSLPPPPPPDSLDQPQPMEQGSSGVLGGKEEGGKPERSSSPAS 877
           AA   +          Q   PP P P S+ QP+P  +              PER ++P  
Sbjct: 224 AAPPPQP---------QPQPPPQPEPRSVPQPEPEPE--------------PEREATPTP 260

Query: 878 ALTPEGEATSVTLVEELSLQEAMRKEPGESSSRKACEVCGQAFPSQAALEEHQKTHPKEG 937
           A                    A  + P     R  C+VCGQ+F     L+ H + H K  
Sbjct: 261 A------------------PAAPEEPPAPPEFR--CQVCGQSFTQSWFLKGHMRKH-KAS 299

Query: 938 PLFTCVFCRQGFLERATLKKHMLLAHHQVQPFAPHGP 974
               C  C + F E   LK HM +   ++ P    GP
Sbjct: 300 FDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPGP 336



 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 103/492 (20%), Positives = 146/492 (29%), Gaps = 67/492 (13%)

Query: 374 KCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKY-----P 428
           +C+ C + F     L+ H+R H     + C VCG  F     LK H   H  K      P
Sbjct: 275 RCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAP 334

Query: 429 HVQMNPHPVPEHLDYVITSSGLPYGMSVPPEKAEEEAATPGGGVERKPLVASTTALSATE 488
                P   P+  D      GL     + P      A TP    E  P +    +L A E
Sbjct: 335 GPASGPARAPQPPDL-----GLLAYEPLGPALLLAPAPTPAERRE-PPSLLGYLSLRAGE 388

Query: 489 SLTLLSTSAGTATAPGLPAFNKFVLMKAVEPKNKADENTPPGSEGSAISGVAESSTATRM 548
                    G    PG  +F  F  + +  P            E   +    E + A   
Sbjct: 389 GRP---NGEGAEPGPGR-SFGGFRPLSSALPARARRHRAEEPEEEEEVVEAEEETWARGR 444

Query: 549 QLSKLVTSLPSWALLTNHFKSTGSFPFPYVLEPLGASPSETSKLQQLVEKIDRQGAVAVT 608
            L  L +  P       H  S             GA    T+  ++              
Sbjct: 445 SLGSLASLHPRPGEGPGHSASAA-----------GAQARSTATQEE-------------- 479

Query: 609 SAASGAPTTSAPAPSSSASSGPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAF 668
                        P     +    C  C +       L++H   H GERP+KC  C  A 
Sbjct: 480 ----NGLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAG 535

Query: 669 STRGNLRAHFVGHKASPAARAQNSCPICQKKFTNAVTLQQHVRMHLGGQIPNGGTALPEG 728
           +  G+L+ H   H     + A    P             +       G  P  G A P  
Sbjct: 536 TQSGSLKYHLQRHHREQRSGAGPGPP------------PEPPPPSQRGSAPQSG-AKPSP 582

Query: 729 GGAAQENGSEQSTVSGAGSFPQQQSQQPSPEEELSEEEEEEDEEEEEDVTDEDSLAGRGS 788
             A    G+       +G+ P  + +  SP   L      E E       D    AG G 
Sbjct: 583 QPATWVEGASSPRPPSSGAGPGSRRKPASPGRTLRNGRGGEAEP-----LDLSLRAGPGG 637

Query: 789 ESGGEKAISVRGDSEEASGAEEEVGTVAAAATAGKEMDSNEKTTQQSSLPPP--PPPDSL 846
           E+G   A+        A+GA E    +A          +  +   Q+   PP    P   
Sbjct: 638 EAGPGGALHRCLFCPFATGAPE---LMALHLQVHHSRRARGRRPPQADASPPYARVPSGE 694

Query: 847 DQPQPMEQGSSG 858
             P P ++G  G
Sbjct: 695 TPPSPSQEGEEG 706



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 27/80 (33%), Positives = 39/80 (48%), Gaps = 1/80 (1%)

Query: 350 PKNGSGELSYGEVMGPLEKPGGRH-KCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGN 408
           P   +G L  G V     + G R   C  C K F  +S L +HLR+H G + ++C  CG+
Sbjct: 33  PAVSAGSLGMGAVSWSESRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGH 92

Query: 409 RFTTRGNLKVHFHRHREKYP 428
           R   R  L+ H   H+ + P
Sbjct: 93  RAAQRALLRSHLRTHQPERP 112



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 104/447 (23%), Positives = 146/447 (32%), Gaps = 57/447 (12%)

Query: 394 SHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPHVQ--MNPHPVPEHLDYVITSSGLP 451
           S  GER + C VCG RF     L +H   H    P  Q    PH         +  S L 
Sbjct: 50  SRAGERRFPCPVCGKRFRFNSILALHLRAH----PGAQAFQCPHCGHRAAQRALLRSHL- 104

Query: 452 YGMSVPPEKAEEEAATPGGGVERKPLVASTTALSATESLTLLSTSAGTATA-PGLPAFNK 510
              +  PE+    AA     +E + L+       A  S  + +T A    A P  P+ + 
Sbjct: 105 --RTHQPERPRSPAARLLLELEERALLREARLGRARSSGGMQATPATEGLARPQAPSSSA 162

Query: 511 FVLMKAVEPKNKADENTPPGSEGSAI-------SGVAESSTATRMQLSKLVTSLPSWALL 563
           F       P  K    T    E            G+    ++   +L  L  SL +    
Sbjct: 163 FRC-----PYCKGKFRTSAERERHLHILHRPWKCGLCSFGSSQEEEL--LHHSLTAHGAP 215

Query: 564 TNHFKSTGSFPFPYVLEPLGASPSETSKLQQLVEKIDRQGAVAVTSAASGAPTTSAPAPS 623
                +T + P P         P   S  Q   E    + A          PT +  AP 
Sbjct: 216 ERPLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEPEREAT---------PTPAPAAPE 266

Query: 624 SSASSGPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGH-- 681
              +    +C +C +  +    L+ H  +H       C VCGR F     L+ H   H  
Sbjct: 267 EPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHAS 326

Query: 682 ---------KASPAARAQNSCP---ICQKKFTNAVTLQQHVRMHLGGQIPN--GGTALPE 727
                     AS  ARA        +  +    A+ L          + P+  G  +L  
Sbjct: 327 KLGPLRAPGPASGPARAPQPPDLGLLAYEPLGPALLLAPAPTPAERREPPSLLGYLSLRA 386

Query: 728 GGGAAQENGSEQSTVSGAGSFPQQQSQQPSPEEELSEEEEEEDEEEEEDVTDEDSLAGRG 787
           G G     G+E       G F    S  P+          EE EEEEE V  E+    RG
Sbjct: 387 GEGRPNGEGAEPGPGRSFGGFRPLSSALPA---RARRHRAEEPEEEEEVVEAEEETWARG 443

Query: 788 SESGGEKAISVR-----GDSEEASGAE 809
              G   ++  R     G S  A+GA+
Sbjct: 444 RSLGSLASLHPRPGEGPGHSASAAGAQ 470



 Score = 36.6 bits (83), Expect = 0.12
 Identities = 42/152 (27%), Positives = 56/152 (36%), Gaps = 27/152 (17%)

Query: 868  KPERSSSPASALTPE------------GEATSVTLVEELSLQEAMRKEPGESSSRKACEV 915
            +PER  SPA+ L  E            G A S   ++     E + +    SSS   C  
Sbjct: 108  QPERPRSPAARLLLELEERALLREARLGRARSSGGMQATPATEGLARPQAPSSSAFRCPY 167

Query: 916  CGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAHHQVQPFAPHGPQ 975
            C   F + A  E H   H    P + C  C  G  +   L  H L AH      AP  P 
Sbjct: 168  CKGKFRTSAERERH--LHILHRP-WKCGLCSFGSSQEEELLHHSLTAHG-----APERP- 218

Query: 976  NIAALSLVPGCSPSITSTGLSPFPRKDDPTIP 1007
             +AA S  P   P        P P+ +  ++P
Sbjct: 219  -LAATSAAPPPQPQ-----PQPPPQPEPRSVP 244



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 43/134 (32%), Positives = 53/134 (39%), Gaps = 16/134 (11%)

Query: 278 YHPLGSQHPFSAGGVGRSHKPTPAPSPALPGSTDQLIASPHLAFPSTTGLLAAQ----CL 333
           YH L   H     G G    P P P P+  GS  Q  A P    P+T    A+       
Sbjct: 543 YH-LQRHHREQRSGAGPGPPPEPPP-PSQRGSAPQSGAKPSPQ-PATWVEGASSPRPPSS 599

Query: 334 GAARGLEAT-ASPGLLKPKNGSG------ELSYGEVMGPLEKPGGR-HKCRFCAKVFGSD 385
           GA  G     ASPG    +NG G      +LS     G    PGG  H+C FC    G+ 
Sbjct: 600 GAGPGSRRKPASPGRTL-RNGRGGEAEPLDLSLRAGPGGEAGPGGALHRCLFCPFATGAP 658

Query: 386 SALQIHLRSHTGER 399
             + +HL+ H   R
Sbjct: 659 ELMALHLQVHHSRR 672


>gi|156415996 zinc finger protein 219 [Homo sapiens]
          Length = 722

 Score = 75.1 bits (183), Expect = 3e-13
 Identities = 89/363 (24%), Positives = 136/363 (37%), Gaps = 36/363 (9%)

Query: 145 PKLGATPLPPESTPAPPPPPPPPPPPGVGSGHLNIPLILEELRVLQQRQIHQMQMTEQIC 204
           P+  ATP P  + P  PP PP       G        +   +R  +    H   +  +  
Sbjct: 252 PEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCF 311

Query: 205 RQVLLLGSLGQTVGAPASPSELPGTGTASSTKPLLPLFSPI--KPVQTSKTLASSSSSSS 262
           ++   L +  +   +   P   PG  +  +  P  P    +  +P+  +  LA + + + 
Sbjct: 312 KEPWFLKNHMKVHASKLGPLRAPGPASGPARAPQPPDLGLLAYEPLGPALLLAPAPTPAE 371

Query: 263 SSSGAETPKQAFFHLYHPLGSQHPFSAG---GVGRSH---KPTPAPSPAL--------PG 308
                  P     +L    G   P   G   G GRS    +P  +  PA         P 
Sbjct: 372 RRE----PPSLLGYLSLRAGEGRPNGEGAEPGPGRSFGGFRPLSSALPARARRHRAEEPE 427

Query: 309 STDQLIASPHLAFPS--TTGLLAAQCLGAARGLEATASPGLLKPKNGSGELSYGEVMGPL 366
             ++++ +    +    + G LA+       G   +AS    + ++ + +   G ++G  
Sbjct: 428 EEEEVVEAEEETWARGRSLGSLASLHPRPGEGPGHSASAAGAQARSTATQEENGLLVGGT 487

Query: 367 EKPGGR----HKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHR 422
              GGR      C FC K F S   L++HLR HTGERPYKC  C    T  G+LK H  R
Sbjct: 488 RPEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQR 547

Query: 423 HREKYPHVQMNPHPVPEHLDYVITSSGLPYGMSVPPEKAE--EEAATP-------GGGVE 473
           H  +       P P PE        S    G    P+ A   E A++P       G G  
Sbjct: 548 HHRE-QRSGAGPGPPPEPPPPSQRGSAPQSGAKPSPQPATWVEGASSPRPPSSGAGPGSR 606

Query: 474 RKP 476
           RKP
Sbjct: 607 RKP 609



 Score = 68.2 bits (165), Expect = 4e-11
 Identities = 86/334 (25%), Positives = 128/334 (38%), Gaps = 65/334 (19%)

Query: 659 FKCKVCGRAFSTRGNLRAHFVGHKASPAARAQNSCPICQKKFTNAVTLQQHVRMH----- 713
           F+C+VCG++F+    L+ H   HKAS      ++CP+C + F     L+ H+++H     
Sbjct: 274 FRCQVCGQSFTQSWFLKGHMRKHKAS----FDHACPVCGRCFKEPWFLKNHMKVHASKLG 329

Query: 714 -LGGQIPNGGTAL----PEGGGAAQENGSEQSTVSGAGSFPQQQSQQPSPEEELSEEEEE 768
            L    P  G A     P+ G  A E       ++ A + P ++ + PS    LS    E
Sbjct: 330 PLRAPGPASGPARAPQPPDLGLLAYEPLGPALLLAPAPT-PAERREPPSLLGYLSLRAGE 388

Query: 769 EDEEEEEDVTDEDSLAGRGSESGGEKAISV-------RGDSEEASGAEEEVGTVAAAATA 821
                      E +  G G   GG + +S        R  +EE    EE V         
Sbjct: 389 GRPN------GEGAEPGPGRSFGGFRPLSSALPARARRHRAEEPEEEEEVVEAEEETWAR 442

Query: 822 GKEMDSNEKTTQQSSLPPPPPPDSLDQPQPMEQGSSGVLGGKEEGGKPERSSSPASALTP 881
           G+ + S       +SL P P                        G  P  S+S A A   
Sbjct: 443 GRSLGS------LASLHPRP------------------------GEGPGHSASAAGA--- 469

Query: 882 EGEATSVTLVEELSLQEA-MRKEPGESSSRKACEVCGQAFPSQAALEEHQKTHPKEGPLF 940
             +A S    EE  L     R E G  ++ K C  CG++F S   L+ H + H  E P +
Sbjct: 470 --QARSTATQEENGLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERP-Y 526

Query: 941 TCVFCRQGFLERATLKKHMLLAHHQVQPFAPHGP 974
            C  C     +  +LK H+   H + +  A  GP
Sbjct: 527 KCPHCDYAGTQSGSLKYHLQRHHREQRSGAGPGP 560



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 85/337 (25%), Positives = 117/337 (34%), Gaps = 70/337 (20%)

Query: 655 GERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARAQNSCPICQKKFTNAVTLQQHVRMHL 714
           GER F C VCG+ F     L  H   H  + A +    CP C  +      L+ H+R H 
Sbjct: 53  GERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQ----CPHCGHRAAQRALLRSHLRTHQ 108

Query: 715 GGQIPNGGTA-----LPEGG-------GAAQENGSEQSTVSGAG-SFPQQQSQQ----PS 757
             + P    A     L E         G A+ +G  Q+T +  G + PQ  S      P 
Sbjct: 109 PER-PRSPAARLLLELEERALLREARLGRARSSGGMQATPATEGLARPQAPSSSAFRCPY 167

Query: 758 PEEELSEEEEEEDEEEEEDVTDEDSLAGRGSESGGEKAISVRGDSEEASGAEEEVGTVAA 817
            + +     E E          +  L   GS    E    +   S  A GA E      +
Sbjct: 168 CKGKFRTSAERERHLHILHRPWKCGLCSFGSSQEEE----LLHHSLTAHGAPERPLAATS 223

Query: 818 AATAGKEMDSNEKTTQQSSLPPPPPPDSLDQPQPMEQGSSGVLGGKEEGGKPERSSSPAS 877
           AA   +          Q   PP P P S+ QP+P  +              PER ++P  
Sbjct: 224 AAPPPQP---------QPQPPPQPEPRSVPQPEPEPE--------------PEREATPTP 260

Query: 878 ALTPEGEATSVTLVEELSLQEAMRKEPGESSSRKACEVCGQAFPSQAALEEHQKTHPKEG 937
           A                    A  + P     R  C+VCGQ+F     L+ H + H K  
Sbjct: 261 A------------------PAAPEEPPAPPEFR--CQVCGQSFTQSWFLKGHMRKH-KAS 299

Query: 938 PLFTCVFCRQGFLERATLKKHMLLAHHQVQPFAPHGP 974
               C  C + F E   LK HM +   ++ P    GP
Sbjct: 300 FDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPGP 336



 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 103/492 (20%), Positives = 146/492 (29%), Gaps = 67/492 (13%)

Query: 374 KCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKY-----P 428
           +C+ C + F     L+ H+R H     + C VCG  F     LK H   H  K      P
Sbjct: 275 RCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAP 334

Query: 429 HVQMNPHPVPEHLDYVITSSGLPYGMSVPPEKAEEEAATPGGGVERKPLVASTTALSATE 488
                P   P+  D      GL     + P      A TP    E  P +    +L A E
Sbjct: 335 GPASGPARAPQPPDL-----GLLAYEPLGPALLLAPAPTPAERRE-PPSLLGYLSLRAGE 388

Query: 489 SLTLLSTSAGTATAPGLPAFNKFVLMKAVEPKNKADENTPPGSEGSAISGVAESSTATRM 548
                    G    PG  +F  F  + +  P            E   +    E + A   
Sbjct: 389 GRP---NGEGAEPGPGR-SFGGFRPLSSALPARARRHRAEEPEEEEEVVEAEEETWARGR 444

Query: 549 QLSKLVTSLPSWALLTNHFKSTGSFPFPYVLEPLGASPSETSKLQQLVEKIDRQGAVAVT 608
            L  L +  P       H  S             GA    T+  ++              
Sbjct: 445 SLGSLASLHPRPGEGPGHSASAA-----------GAQARSTATQEE-------------- 479

Query: 609 SAASGAPTTSAPAPSSSASSGPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAF 668
                        P     +    C  C +       L++H   H GERP+KC  C  A 
Sbjct: 480 ----NGLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAG 535

Query: 669 STRGNLRAHFVGHKASPAARAQNSCPICQKKFTNAVTLQQHVRMHLGGQIPNGGTALPEG 728
           +  G+L+ H   H     + A    P             +       G  P  G A P  
Sbjct: 536 TQSGSLKYHLQRHHREQRSGAGPGPP------------PEPPPPSQRGSAPQSG-AKPSP 582

Query: 729 GGAAQENGSEQSTVSGAGSFPQQQSQQPSPEEELSEEEEEEDEEEEEDVTDEDSLAGRGS 788
             A    G+       +G+ P  + +  SP   L      E E       D    AG G 
Sbjct: 583 QPATWVEGASSPRPPSSGAGPGSRRKPASPGRTLRNGRGGEAEP-----LDLSLRAGPGG 637

Query: 789 ESGGEKAISVRGDSEEASGAEEEVGTVAAAATAGKEMDSNEKTTQQSSLPPP--PPPDSL 846
           E+G   A+        A+GA E    +A          +  +   Q+   PP    P   
Sbjct: 638 EAGPGGALHRCLFCPFATGAPE---LMALHLQVHHSRRARGRRPPQADASPPYARVPSGE 694

Query: 847 DQPQPMEQGSSG 858
             P P ++G  G
Sbjct: 695 TPPSPSQEGEEG 706



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 27/80 (33%), Positives = 39/80 (48%), Gaps = 1/80 (1%)

Query: 350 PKNGSGELSYGEVMGPLEKPGGRH-KCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGN 408
           P   +G L  G V     + G R   C  C K F  +S L +HLR+H G + ++C  CG+
Sbjct: 33  PAVSAGSLGMGAVSWSESRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGH 92

Query: 409 RFTTRGNLKVHFHRHREKYP 428
           R   R  L+ H   H+ + P
Sbjct: 93  RAAQRALLRSHLRTHQPERP 112



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 104/447 (23%), Positives = 146/447 (32%), Gaps = 57/447 (12%)

Query: 394 SHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPHVQ--MNPHPVPEHLDYVITSSGLP 451
           S  GER + C VCG RF     L +H   H    P  Q    PH         +  S L 
Sbjct: 50  SRAGERRFPCPVCGKRFRFNSILALHLRAH----PGAQAFQCPHCGHRAAQRALLRSHL- 104

Query: 452 YGMSVPPEKAEEEAATPGGGVERKPLVASTTALSATESLTLLSTSAGTATA-PGLPAFNK 510
              +  PE+    AA     +E + L+       A  S  + +T A    A P  P+ + 
Sbjct: 105 --RTHQPERPRSPAARLLLELEERALLREARLGRARSSGGMQATPATEGLARPQAPSSSA 162

Query: 511 FVLMKAVEPKNKADENTPPGSEGSAI-------SGVAESSTATRMQLSKLVTSLPSWALL 563
           F       P  K    T    E            G+    ++   +L  L  SL +    
Sbjct: 163 FRC-----PYCKGKFRTSAERERHLHILHRPWKCGLCSFGSSQEEEL--LHHSLTAHGAP 215

Query: 564 TNHFKSTGSFPFPYVLEPLGASPSETSKLQQLVEKIDRQGAVAVTSAASGAPTTSAPAPS 623
                +T + P P         P   S  Q   E    + A          PT +  AP 
Sbjct: 216 ERPLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEPEREAT---------PTPAPAAPE 266

Query: 624 SSASSGPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGH-- 681
              +    +C +C +  +    L+ H  +H       C VCGR F     L+ H   H  
Sbjct: 267 EPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHAS 326

Query: 682 ---------KASPAARAQNSCP---ICQKKFTNAVTLQQHVRMHLGGQIPN--GGTALPE 727
                     AS  ARA        +  +    A+ L          + P+  G  +L  
Sbjct: 327 KLGPLRAPGPASGPARAPQPPDLGLLAYEPLGPALLLAPAPTPAERREPPSLLGYLSLRA 386

Query: 728 GGGAAQENGSEQSTVSGAGSFPQQQSQQPSPEEELSEEEEEEDEEEEEDVTDEDSLAGRG 787
           G G     G+E       G F    S  P+          EE EEEEE V  E+    RG
Sbjct: 387 GEGRPNGEGAEPGPGRSFGGFRPLSSALPA---RARRHRAEEPEEEEEVVEAEEETWARG 443

Query: 788 SESGGEKAISVR-----GDSEEASGAE 809
              G   ++  R     G S  A+GA+
Sbjct: 444 RSLGSLASLHPRPGEGPGHSASAAGAQ 470



 Score = 36.6 bits (83), Expect = 0.12
 Identities = 42/152 (27%), Positives = 56/152 (36%), Gaps = 27/152 (17%)

Query: 868  KPERSSSPASALTPE------------GEATSVTLVEELSLQEAMRKEPGESSSRKACEV 915
            +PER  SPA+ L  E            G A S   ++     E + +    SSS   C  
Sbjct: 108  QPERPRSPAARLLLELEERALLREARLGRARSSGGMQATPATEGLARPQAPSSSAFRCPY 167

Query: 916  CGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAHHQVQPFAPHGPQ 975
            C   F + A  E H   H    P + C  C  G  +   L  H L AH      AP  P 
Sbjct: 168  CKGKFRTSAERERH--LHILHRP-WKCGLCSFGSSQEEELLHHSLTAHG-----APERP- 218

Query: 976  NIAALSLVPGCSPSITSTGLSPFPRKDDPTIP 1007
             +AA S  P   P        P P+ +  ++P
Sbjct: 219  -LAATSAAPPPQPQ-----PQPPPQPEPRSVP 244



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 43/134 (32%), Positives = 53/134 (39%), Gaps = 16/134 (11%)

Query: 278 YHPLGSQHPFSAGGVGRSHKPTPAPSPALPGSTDQLIASPHLAFPSTTGLLAAQ----CL 333
           YH L   H     G G    P P P P+  GS  Q  A P    P+T    A+       
Sbjct: 543 YH-LQRHHREQRSGAGPGPPPEPPP-PSQRGSAPQSGAKPSPQ-PATWVEGASSPRPPSS 599

Query: 334 GAARGLEAT-ASPGLLKPKNGSG------ELSYGEVMGPLEKPGGR-HKCRFCAKVFGSD 385
           GA  G     ASPG    +NG G      +LS     G    PGG  H+C FC    G+ 
Sbjct: 600 GAGPGSRRKPASPGRTL-RNGRGGEAEPLDLSLRAGPGGEAGPGGALHRCLFCPFATGAP 658

Query: 386 SALQIHLRSHTGER 399
             + +HL+ H   R
Sbjct: 659 ELMALHLQVHHSRR 672


>gi|32469511 B-cell CLL/lymphoma 6, member B (zinc finger protein)
           [Homo sapiens]
          Length = 480

 Score = 74.7 bits (182), Expect = 4e-13
 Identities = 83/288 (28%), Positives = 107/288 (37%), Gaps = 45/288 (15%)

Query: 147 LGATPLPPESTPAPPPPPPPPPPPGVGSGHLNIPLILEELRVLQQRQIHQMQMTEQICR- 205
           LG +  P E+ P  PP  PPP  P    GH + P    E R   Q          + C  
Sbjct: 138 LGISLRPLEAEPPTPPTAPPPGSPRRSEGHPDPPT---ESRSCSQGPPSPASPDPKACNW 194

Query: 206 ---QVLLLGSLGQTVGAPASPSELPGTGTASSTKPLLPLFSPIKPVQTSKTLASSSSSSS 262
              + ++L S     G+          G  SS +P      P   + +    +SSSSSSS
Sbjct: 195 KKYKYIVLNSQASQAGSLV--------GERSSGQPC-----PQARLPSGDEASSSSSSSS 241

Query: 263 SSSGAETPKQAFFHLYHPLGSQHPFSAGGVGRSHKPTPAPSPALPGSTDQ-LIASPHLAF 321
           SSS  E P         P  +   F  G         PA +P L  S  Q    SP    
Sbjct: 242 SSSSEEGPIPGPQSRLSPTAATVQFKCGA--------PASTPYLLTSQAQDTSGSPSERA 293

Query: 322 PSTTGLLAAQCLGAARGLEATASPGLLKPKNGSGELSYGEVMGPLEKPGGRHKCRFCAKV 381
               G     C    +  EA A        +G   L    V G  +KP   +KC+ C   
Sbjct: 294 RPLPGSEFFSC----QNCEAVAGCS-----SGLDSL----VPGDEDKP---YKCQLCRSS 337

Query: 382 FGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPH 429
           F     L  H   HTGE+PY C++CG RF    NLK H   H  + P+
Sbjct: 338 FRYKGNLASHRTVHTGEKPYHCSICGARFNRPANLKTHSRIHSGEKPY 385



 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 61/215 (28%), Positives = 83/215 (38%), Gaps = 32/215 (14%)

Query: 528 PPGSEGSAISGVAESSTATRMQLSKLVTSLPSWALLTNHFKSTGSFPFPYVL----EPLG 583
           P G E S+ S  + SS++    +    + L   A  T  FK       PY+L    +   
Sbjct: 228 PSGDEASSSSSSSSSSSSEEGPIPGPQSRLSPTAA-TVQFKCGAPASTPYLLTSQAQDTS 286

Query: 584 ASPSETSKLQQLVEKIDRQGAVAVTSAASGA----------PTTSAPAPSSSASSG---- 629
            SPSE ++     E    Q   AV   +SG           P       SS    G    
Sbjct: 287 GSPSERARPLPGSEFFSCQNCEAVAGCSSGLDSLVPGDEDKPYKCQLCRSSFRYKGNLAS 346

Query: 630 ---------PNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVG 680
                    P  C IC    + P  L+ H   H GE+P+KC+ CG  F    +LRAH + 
Sbjct: 347 HRTVHTGEKPYHCSICGARFNRPANLKTHSRIHSGEKPYKCETCGSRFVQVAHLRAHVLI 406

Query: 681 HKASPAARAQNSCPICQKKFTNAVTLQQHVRMHLG 715
           H           CP C  +F +  TL+ HVR+H G
Sbjct: 407 H----TGEKPYPCPTCGTRFRHLQTLKSHVRIHTG 437



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 22/69 (31%), Positives = 35/69 (50%), Gaps = 3/69 (4%)

Query: 367 EKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREK 426
           EKP   + C  C   F     L+ H+R HTGE+PY C+ CG  F  +  L++H  +    
Sbjct: 410 EKP---YPCPTCGTRFRHLQTLKSHVRIHTGEKPYHCDPCGLHFRHKSQLRLHLRQKHGA 466

Query: 427 YPHVQMNPH 435
             + +++ H
Sbjct: 467 ATNTKVHYH 475



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 19/66 (28%), Positives = 29/66 (43%), Gaps = 2/66 (3%)

Query: 904 PGESSSRKACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAH 963
           PG+      C++C  +F  +  L  H+  H  E P + C  C   F   A LK H  + H
Sbjct: 322 PGDEDKPYKCQLCRSSFRYKGNLASHRTVHTGEKP-YHCSICGARFNRPANLKTHSRI-H 379

Query: 964 HQVQPF 969
              +P+
Sbjct: 380 SGEKPY 385



 Score = 34.3 bits (77), Expect = 0.61
 Identities = 20/57 (35%), Positives = 25/57 (43%), Gaps = 2/57 (3%)

Query: 913 CEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAHHQVQPF 969
           CE CG  F   A L  H   H  E P + C  C   F    TLK H+ + H   +P+
Sbjct: 387 CETCGSRFVQVAHLRAHVLIHTGEKP-YPCPTCGTRFRHLQTLKSHVRI-HTGEKPY 441



 Score = 34.3 bits (77), Expect = 0.61
 Identities = 16/48 (33%), Positives = 21/48 (43%)

Query: 630 PNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAH 677
           P  C  C       + L+ H   H GE+P+ C  CG  F  +  LR H
Sbjct: 412 PYPCPTCGTRFRHLQTLKSHVRIHTGEKPYHCDPCGLHFRHKSQLRLH 459


>gi|194018515 zinc finger protein 443 [Homo sapiens]
          Length = 671

 Score = 72.8 bits (177), Expect = 2e-12
 Identities = 31/86 (36%), Positives = 47/86 (54%), Gaps = 4/86 (4%)

Query: 628 SGPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAA 687
           +GP++C IC +   CP +L+ H   H GE+P++CK CG+A S R + R+H + H      
Sbjct: 362 NGPHKCKICGKGFDCPSSLQSHERTHTGEKPYECKQCGKALSHRSSFRSHMIMHTGD--- 418

Query: 688 RAQNSCPICQKKFTNAVTLQQHVRMH 713
              + C +C K F      Q+H R H
Sbjct: 419 -GPHKCKVCGKAFVYPSVFQRHERTH 443



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 26/59 (44%), Positives = 34/59 (57%)

Query: 371 GRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPH 429
           G HKC+ C K F   S+LQ H R+HTGE+PY+C  CG   + R + + H   H    PH
Sbjct: 363 GPHKCKICGKGFDCPSSLQSHERTHTGEKPYECKQCGKALSHRSSFRSHMIMHTGDGPH 421



 Score = 60.5 bits (145), Expect = 8e-09
 Identities = 27/63 (42%), Positives = 38/63 (60%), Gaps = 3/63 (4%)

Query: 367 EKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREK 426
           EKP   +KC+ C+K F   S+  IH R+HTGE+PY C  CG  F+  G+L+ H   H  +
Sbjct: 278 EKP---YKCKQCSKAFPDSSSCLIHERTHTGEKPYTCKQCGKAFSVSGSLQRHETTHSAE 334

Query: 427 YPH 429
            P+
Sbjct: 335 KPY 337



 Score = 57.4 bits (137), Expect = 7e-08
 Identities = 28/86 (32%), Positives = 43/86 (50%), Gaps = 4/86 (4%)

Query: 630 PNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARA 689
           P +C  C +      +  +H   H GE+P+ CK CG+AFS  G+L+ H   H    +A  
Sbjct: 280 PYKCKQCSKAFPDSSSCLIHERTHTGEKPYTCKQCGKAFSVSGSLQRHETTH----SAEK 335

Query: 690 QNSCPICQKKFTNAVTLQQHVRMHLG 715
             +C  C K F +  + Q+H+  H G
Sbjct: 336 PYACQQCGKAFHHLGSFQRHMIRHTG 361



 Score = 57.4 bits (137), Expect = 7e-08
 Identities = 24/59 (40%), Positives = 32/59 (54%)

Query: 371 GRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPH 429
           G HKC+ C K F   S  Q H R+HT E+PYKC  CG  +    +L+ H   H  + P+
Sbjct: 419 GPHKCKVCGKAFVYPSVFQRHERTHTAEKPYKCKQCGKAYRISSSLRRHETTHTGEKPY 477



 Score = 57.0 bits (136), Expect = 9e-08
 Identities = 30/110 (27%), Positives = 43/110 (39%), Gaps = 23/110 (20%)

Query: 629 GPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAH----------- 677
           GP++C +C +    P   + H   H  E+P+KCK CG+A+    +LR H           
Sbjct: 419 GPHKCKVCGKAFVYPSVFQRHERTHTAEKPYKCKQCGKAYRISSSLRRHETTHTGEKPYK 478

Query: 678 ------------FVGHKASPAARAQNSCPICQKKFTNAVTLQQHVRMHLG 715
                       F  HK +        C  C K F+    L +H R H G
Sbjct: 479 CKLGKAFIDFCSFQNHKTTHTGEKPYECKECGKAFSRFRYLSRHKRTHTG 528



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 4/87 (4%)

Query: 629 GPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAAR 688
           GP +C +C +    P  L +H   H GE+P++CK C +AFS      + ++ H+ +    
Sbjct: 195 GPYKCKLCGKAFFWPSLLHMHERTHTGEKPYECKQCSKAFS----FYSSYLRHERTHTGE 250

Query: 689 AQNSCPICQKKFTNAVTLQQHVRMHLG 715
               C  C K F    +  +H R H G
Sbjct: 251 KPYECKQCSKAFPFYSSYLRHERTHTG 277



 Score = 54.3 bits (129), Expect = 6e-07
 Identities = 26/63 (41%), Positives = 34/63 (53%), Gaps = 3/63 (4%)

Query: 367 EKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREK 426
           EKP   ++C+ C K F     L  H R+HTGE+PY+C  C   F    NLKVH   H  +
Sbjct: 501 EKP---YECKECGKAFSRFRYLSRHKRTHTGEKPYECKTCRKAFGHYDNLKVHERIHSGE 557

Query: 427 YPH 429
            P+
Sbjct: 558 KPY 560



 Score = 53.9 bits (128), Expect = 7e-07
 Identities = 32/110 (29%), Positives = 44/110 (40%), Gaps = 24/110 (21%)

Query: 630 PNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAH------------ 677
           P +C  C +  S  R L  H   H GE+P++CK C +AF    NL+ H            
Sbjct: 503 PYECKECGKAFSRFRYLSRHKRTHTGEKPYECKTCRKAFGHYDNLKVHERIHSGEKPYEC 562

Query: 678 ------------FVGHKASPAARAQNSCPICQKKFTNAVTLQQHVRMHLG 715
                       F+ H+          CP C K FT++  LQ H + H G
Sbjct: 563 KECGKAFSWLTCFLRHERIHMREKSYECPQCGKAFTHSRFLQGHEKTHTG 612



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 22/64 (34%), Positives = 35/64 (54%)

Query: 366 LEKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHRE 425
           +++  G +KC+ C K F   S L +H R+HTGE+PY+C  C   F+   +   H   H  
Sbjct: 190 VQRGDGPYKCKLCGKAFFWPSLLHMHERTHTGEKPYECKQCSKAFSFYSSYLRHERTHTG 249

Query: 426 KYPH 429
           + P+
Sbjct: 250 EKPY 253



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 24/63 (38%), Positives = 32/63 (50%), Gaps = 3/63 (4%)

Query: 367 EKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREK 426
           EKP   + C+ C K F    +LQ H  +H+ E+PY C  CG  F   G+ + H  RH   
Sbjct: 306 EKP---YTCKQCGKAFSVSGSLQRHETTHSAEKPYACQQCGKAFHHLGSFQRHMIRHTGN 362

Query: 427 YPH 429
            PH
Sbjct: 363 GPH 365



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 26/83 (31%), Positives = 41/83 (49%), Gaps = 1/83 (1%)

Query: 632 QCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGH-KASPAARAQ 690
           +C  C +  +  R L+ H   H GE P++CK CG+AF++  +L  H   H K +      
Sbjct: 589 ECPQCGKAFTHSRFLQGHEKTHTGENPYECKECGKAFASLSSLHRHKKTHWKKTHTGENP 648

Query: 691 NSCPICQKKFTNAVTLQQHVRMH 713
             C  C K F +  +L +H + H
Sbjct: 649 YECKECGKAFASLSSLHRHKKTH 671



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 26/76 (34%), Positives = 36/76 (47%), Gaps = 3/76 (3%)

Query: 354 SGELSYGEVMGPLEKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTR 413
           SG L   E     EKP   + C+ C K F    + Q H+  HTG  P+KC +CG  F   
Sbjct: 321 SGSLQRHETTHSAEKP---YACQQCGKAFHHLGSFQRHMIRHTGNGPHKCKICGKGFDCP 377

Query: 414 GNLKVHFHRHREKYPH 429
            +L+ H   H  + P+
Sbjct: 378 SSLQSHERTHTGEKPY 393



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 38/150 (25%), Positives = 60/150 (40%), Gaps = 6/150 (4%)

Query: 568 KSTGSFPFPYVLEPLGASPSETSKLQQLVEKIDRQGAVAVTSAASGAPTTSAPAPSSSAS 627
           ++T S   PY  +  G +       Q+ + +    G         G    S+        
Sbjct: 328 ETTHSAEKPYACQQCGKAFHHLGSFQRHMIRHTGNGPHKCKICGKGFDCPSSLQSHERTH 387

Query: 628 SG--PNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASP 685
           +G  P +C  C + LS   + R H   H G+ P KCKVCG+AF       + F  H+ + 
Sbjct: 388 TGEKPYECKQCGKALSHRSSFRSHMIMHTGDGPHKCKVCGKAFV----YPSVFQRHERTH 443

Query: 686 AARAQNSCPICQKKFTNAVTLQQHVRMHLG 715
            A     C  C K +  + +L++H   H G
Sbjct: 444 TAEKPYKCKQCGKAYRISSSLRRHETTHTG 473



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 26/70 (37%), Positives = 36/70 (51%), Gaps = 7/70 (10%)

Query: 373 HKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHRE---KYPH 429
           ++C  C K F     LQ H ++HTGE PY+C  CG  F +  +L    HRH++   K  H
Sbjct: 588 YECPQCGKAFTHSRFLQGHEKTHTGENPYECKECGKAFASLSSL----HRHKKTHWKKTH 643

Query: 430 VQMNPHPVPE 439
              NP+   E
Sbjct: 644 TGENPYECKE 653



 Score = 50.4 bits (119), Expect = 8e-06
 Identities = 23/63 (36%), Positives = 34/63 (53%), Gaps = 3/63 (4%)

Query: 367 EKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREK 426
           EKP   ++C+ C+K F   S+   H R+HTGE+PYKC  C   F    +  +H   H  +
Sbjct: 250 EKP---YECKQCSKAFPFYSSYLRHERTHTGEKPYKCKQCSKAFPDSSSCLIHERTHTGE 306

Query: 427 YPH 429
            P+
Sbjct: 307 KPY 309



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 24/78 (30%), Positives = 36/78 (46%), Gaps = 4/78 (5%)

Query: 638 RVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARAQNSCPICQ 697
           +  S   + + H   H G++P+ CK CG++FS+ GNL+ H    +          C +C 
Sbjct: 148 KAFSYHNSFQTHERLHTGKKPYDCKECGKSFSSLGNLQRHMAVQRGD----GPYKCKLCG 203

Query: 698 KKFTNAVTLQQHVRMHLG 715
           K F     L  H R H G
Sbjct: 204 KAFFWPSLLHMHERTHTG 221



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 20/45 (44%), Positives = 29/45 (64%), Gaps = 3/45 (6%)

Query: 367 EKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFT 411
           EKP   ++C+ C K FG    L++H R H+GE+PY+C  CG  F+
Sbjct: 529 EKP---YECKTCRKAFGHYDNLKVHERIHSGEKPYECKECGKAFS 570



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 26/63 (41%), Positives = 34/63 (53%), Gaps = 3/63 (4%)

Query: 367 EKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREK 426
           EKP   HK R   K F   ++ Q H R HTG++PY C  CG  F++ GNL+ H    R  
Sbjct: 138 EKPD-THKQR--GKAFSYHNSFQTHERLHTGKKPYDCKECGKSFSSLGNLQRHMAVQRGD 194

Query: 427 YPH 429
            P+
Sbjct: 195 GPY 197



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 22/60 (36%), Positives = 34/60 (56%), Gaps = 9/60 (15%)

Query: 373 HKCRFCAKVFGSDSALQIHLRSH-----TGERPYKCNVCGNRFTTRGNLKVHFHRHREKY 427
           ++C+ C K F S S+L  H ++H     TGE PY+C  CG  F +  +L    HRH++ +
Sbjct: 616 YECKECGKAFASLSSLHRHKKTHWKKTHTGENPYECKECGKAFASLSSL----HRHKKTH 671



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 22/63 (34%), Positives = 33/63 (52%), Gaps = 3/63 (4%)

Query: 367 EKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREK 426
           EKP   ++C+ C+K F   S+   H R+HTGE+PY+C  C   F    +   H   H  +
Sbjct: 222 EKP---YECKQCSKAFSFYSSYLRHERTHTGEKPYECKQCSKAFPFYSSYLRHERTHTGE 278

Query: 427 YPH 429
            P+
Sbjct: 279 KPY 281



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 20/57 (35%), Positives = 28/57 (49%)

Query: 373 HKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPH 429
           + C+ C K F S   LQ H+    G+ PYKC +CG  F     L +H   H  + P+
Sbjct: 169 YDCKECGKSFSSLGNLQRHMAVQRGDGPYKCKLCGKAFFWPSLLHMHERTHTGEKPY 225



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 24/84 (28%), Positives = 36/84 (42%), Gaps = 4/84 (4%)

Query: 630 PNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARA 689
           P +C  C +      +   H   H GE+P+KCK C +AF    +   H   H        
Sbjct: 252 PYECKQCSKAFPFYSSYLRHERTHTGEKPYKCKQCSKAFPDSSSCLIHERTH----TGEK 307

Query: 690 QNSCPICQKKFTNAVTLQQHVRMH 713
             +C  C K F+ + +LQ+H   H
Sbjct: 308 PYTCKQCGKAFSVSGSLQRHETTH 331



 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 23/63 (36%), Positives = 35/63 (55%), Gaps = 4/63 (6%)

Query: 367 EKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREK 426
           EKP   +KC+ C K +   S+L+ H  +HTGE+PYKC + G  F    + + H   H  +
Sbjct: 446 EKP---YKCKQCGKAYRISSSLRRHETTHTGEKPYKCKL-GKAFIDFCSFQNHKTTHTGE 501

Query: 427 YPH 429
            P+
Sbjct: 502 KPY 504



 Score = 43.9 bits (102), Expect = 8e-04
 Identities = 26/86 (30%), Positives = 35/86 (40%), Gaps = 4/86 (4%)

Query: 630 PNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARA 689
           P  C  C +  S    L+ H     G+ P+KCK+CG+AF     L  H   H        
Sbjct: 168 PYDCKECGKSFSSLGNLQRHMAVQRGDGPYKCKLCGKAFFWPSLLHMHERTH----TGEK 223

Query: 690 QNSCPICQKKFTNAVTLQQHVRMHLG 715
              C  C K F+   +  +H R H G
Sbjct: 224 PYECKQCSKAFSFYSSYLRHERTHTG 249



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 19/67 (28%), Positives = 36/67 (53%), Gaps = 3/67 (4%)

Query: 895 SLQEAMRKEPGESSSRKACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERAT 954
           S Q  M +  G    +  C++CG+ F   ++L+ H++TH  E P + C  C +    R++
Sbjct: 351 SFQRHMIRHTGNGPHK--CKICGKGFDCPSSLQSHERTHTGEKP-YECKQCGKALSHRSS 407

Query: 955 LKKHMLL 961
            + HM++
Sbjct: 408 FRSHMIM 414



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 23/63 (36%), Positives = 32/63 (50%), Gaps = 4/63 (6%)

Query: 367 EKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREK 426
           EKP   +KC+   K F    + Q H  +HTGE+PY+C  CG  F+    L  H   H  +
Sbjct: 474 EKP---YKCKL-GKAFIDFCSFQNHKTTHTGEKPYECKECGKAFSRFRYLSRHKRTHTGE 529

Query: 427 YPH 429
            P+
Sbjct: 530 KPY 532



 Score = 39.7 bits (91), Expect = 0.014
 Identities = 19/58 (32%), Positives = 32/58 (55%), Gaps = 2/58 (3%)

Query: 913 CEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHMLLAHHQVQPFA 970
           C+ C +AFP  ++   H++TH  E P +TC  C + F    +L++H    H   +P+A
Sbjct: 283 CKQCSKAFPDSSSCLIHERTHTGEKP-YTCKQCGKAFSVSGSLQRHE-TTHSAEKPYA 338



 Score = 39.7 bits (91), Expect = 0.014
 Identities = 16/48 (33%), Positives = 27/48 (56%), Gaps = 1/48 (2%)

Query: 913 CEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHML 960
           C+ CG+AF    +L+ H+ TH  E P + C  C + F    + ++HM+
Sbjct: 311 CKQCGKAFSVSGSLQRHETTHSAEKP-YACQQCGKAFHHLGSFQRHMI 357



 Score = 39.3 bits (90), Expect = 0.019
 Identities = 21/63 (33%), Positives = 30/63 (47%), Gaps = 3/63 (4%)

Query: 367 EKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREK 426
           EKP   ++C+ C K F   +    H R H  E+ Y+C  CG  FT    L+ H   H  +
Sbjct: 557 EKP---YECKECGKAFSWLTCFLRHERIHMREKSYECPQCGKAFTHSRFLQGHEKTHTGE 613

Query: 427 YPH 429
            P+
Sbjct: 614 NPY 616



 Score = 38.5 bits (88), Expect = 0.032
 Identities = 15/46 (32%), Positives = 28/46 (60%), Gaps = 1/46 (2%)

Query: 913 CEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKH 958
           C+VCG+AF   +  + H++TH  E P + C  C + +   ++L++H
Sbjct: 423 CKVCGKAFVYPSVFQRHERTHTAEKP-YKCKQCGKAYRISSSLRRH 467



 Score = 38.5 bits (88), Expect = 0.032
 Identities = 17/46 (36%), Positives = 25/46 (54%), Gaps = 1/46 (2%)

Query: 913 CEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKH 958
           C  CG+AF     L+ H+KTH  E P + C  C + F   ++L +H
Sbjct: 590 CPQCGKAFTHSRFLQGHEKTHTGENP-YECKECGKAFASLSSLHRH 634



 Score = 37.4 bits (85), Expect = 0.072
 Identities = 19/51 (37%), Positives = 29/51 (56%), Gaps = 6/51 (11%)

Query: 913 CEVCGQAFPSQAALEEHQKTHPK-----EGPLFTCVFCRQGFLERATLKKH 958
           C+ CG+AF S ++L  H+KTH K     E P + C  C + F   ++L +H
Sbjct: 618 CKECGKAFASLSSLHRHKKTHWKKTHTGENP-YECKECGKAFASLSSLHRH 667



 Score = 37.0 bits (84), Expect = 0.093
 Identities = 18/46 (39%), Positives = 24/46 (52%), Gaps = 1/46 (2%)

Query: 913 CEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKH 958
           C+ CG+AF     L  H++TH  E P + C  CR+ F     LK H
Sbjct: 506 CKECGKAFSRFRYLSRHKRTHTGEKP-YECKTCRKAFGHYDNLKVH 550



 Score = 35.8 bits (81), Expect = 0.21
 Identities = 26/94 (27%), Positives = 42/94 (44%), Gaps = 5/94 (5%)

Query: 869 PERSSSPASALTPEGEA--TSVTLVEELSLQEAMRKEPGESSSRK--ACEVCGQAFPSQA 924
           P+ SS      T  GE   T     +  S+  ++++     S+ K  AC+ CG+AF    
Sbjct: 291 PDSSSCLIHERTHTGEKPYTCKQCGKAFSVSGSLQRHETTHSAEKPYACQQCGKAFHHLG 350

Query: 925 ALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKH 958
           + + H   H   GP   C  C +GF   ++L+ H
Sbjct: 351 SFQRHMIRHTGNGP-HKCKICGKGFDCPSSLQSH 383



 Score = 34.7 bits (78), Expect = 0.46
 Identities = 19/64 (29%), Positives = 34/64 (53%), Gaps = 3/64 (4%)

Query: 895 SLQEAMRKEPGESSSRKACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERAT 954
           +LQ  M  + G+   +  C++CG+AF   + L  H++TH  E P + C  C + F   ++
Sbjct: 183 NLQRHMAVQRGDGPYK--CKLCGKAFFWPSLLHMHERTHTGEKP-YECKQCSKAFSFYSS 239

Query: 955 LKKH 958
             +H
Sbjct: 240 YLRH 243



 Score = 33.5 bits (75), Expect = 1.0
 Identities = 18/64 (28%), Positives = 29/64 (45%), Gaps = 3/64 (4%)

Query: 895 SLQEAMRKEPGESSSRKACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERAT 954
           SLQ   R   GE      C+ CG+A   +++   H   H  +GP   C  C + F+  + 
Sbjct: 379 SLQSHERTHTGEKPYE--CKQCGKALSHRSSFRSHMIMHTGDGP-HKCKVCGKAFVYPSV 435

Query: 955 LKKH 958
            ++H
Sbjct: 436 FQRH 439



 Score = 32.7 bits (73), Expect = 1.8
 Identities = 14/46 (30%), Positives = 25/46 (54%), Gaps = 1/46 (2%)

Query: 913 CEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKH 958
           C+ C +AFP  ++   H++TH  E P + C  C + F + ++   H
Sbjct: 255 CKQCSKAFPFYSSYLRHERTHTGEKP-YKCKQCSKAFPDSSSCLIH 299



 Score = 31.6 bits (70), Expect = 3.9
 Identities = 14/46 (30%), Positives = 22/46 (47%), Gaps = 1/46 (2%)

Query: 913 CEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKH 958
           C+ CG++F S   L+ H      +GP + C  C + F   + L  H
Sbjct: 171 CKECGKSFSSLGNLQRHMAVQRGDGP-YKCKLCGKAFFWPSLLHMH 215



 Score = 30.8 bits (68), Expect = 6.7
 Identities = 18/61 (29%), Positives = 28/61 (45%), Gaps = 4/61 (6%)

Query: 655 GERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARAQNSCPICQKKFTNAVTLQQHVRMHL 714
           GE+P   K  G+AFS   + + H   H      +    C  C K F++   LQ+H+ +  
Sbjct: 137 GEKPDTHKQRGKAFSYHNSFQTHERLH----TGKKPYDCKECGKSFSSLGNLQRHMAVQR 192

Query: 715 G 715
           G
Sbjct: 193 G 193



 Score = 30.8 bits (68), Expect = 6.7
 Identities = 11/21 (52%), Positives = 16/21 (76%)

Query: 913 CEVCGQAFPSQAALEEHQKTH 933
           C+ CG+AF S ++L  H+KTH
Sbjct: 651 CKECGKAFASLSSLHRHKKTH 671


>gi|33438586 zinc finger protein 77 [Homo sapiens]
          Length = 545

 Score = 71.6 bits (174), Expect = 3e-12
 Identities = 39/105 (37%), Positives = 52/105 (49%), Gaps = 4/105 (3%)

Query: 611 ASGAPTTSAPAPSSSASSGPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFST 670
           A G PT       + +   P QC  C +  S   +LR+H   H GE+PF+CK CG+AFS 
Sbjct: 388 AFGCPTYFRRHVKTHSGVKPYQCKECGKAYSFSSSLRIHVRTHTGEKPFECKHCGKAFSC 447

Query: 671 RGNLRAHFVGHKASPAARAQNSCPICQKKFTNAVTLQQHVRMHLG 715
             +LR H   H    +      C  C K F++A   Q+HVR H G
Sbjct: 448 HSSLREHVRTH----SGEKPYECNQCGKAFSHAQYFQKHVRSHSG 488



 Score = 63.5 bits (153), Expect = 9e-10
 Identities = 31/86 (36%), Positives = 43/86 (50%), Gaps = 4/86 (4%)

Query: 630 PNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARA 689
           P +C  C +  SCP   R H   H GE+P++CK CG++FS   + R H   H      + 
Sbjct: 267 PYECKECGKAFSCPSYFREHVRTHTGEKPYECKHCGKSFSCYSSFRDHVRTHTGEKPCQ- 325

Query: 690 QNSCPICQKKFTNAVTLQQHVRMHLG 715
              C  C K FT   +L++H R H G
Sbjct: 326 ---CKHCGKAFTCYSSLREHGRTHSG 348



 Score = 61.2 bits (147), Expect = 5e-09
 Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 4/86 (4%)

Query: 630 PNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARA 689
           P  C  C +   CP   R H   H G +P++CK CG+A+S   +LR H   H        
Sbjct: 379 PYVCKQCGKAFGCPTYFRRHVKTHSGVKPYQCKECGKAYSFSSSLRIHVRTH----TGEK 434

Query: 690 QNSCPICQKKFTNAVTLQQHVRMHLG 715
              C  C K F+   +L++HVR H G
Sbjct: 435 PFECKHCGKAFSCHSSLREHVRTHSG 460



 Score = 60.5 bits (145), Expect = 8e-09
 Identities = 31/86 (36%), Positives = 42/86 (48%), Gaps = 4/86 (4%)

Query: 630 PNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARA 689
           P QC  C +  +C  +LR H   H GE+P++CK CG+AF    +LRAH   H        
Sbjct: 323 PCQCKHCGKAFTCYSSLREHGRTHSGEKPYECKECGKAFRYPSSLRAHMRMH----TGEK 378

Query: 690 QNSCPICQKKFTNAVTLQQHVRMHLG 715
              C  C K F      ++HV+ H G
Sbjct: 379 PYVCKQCGKAFGCPTYFRRHVKTHSG 404



 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 21/57 (36%), Positives = 37/57 (64%)

Query: 373 HKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPH 429
           ++C+ C K +   S+L+IH+R+HTGE+P++C  CG  F+   +L+ H   H  + P+
Sbjct: 408 YQCKECGKAYSFSSSLRIHVRTHTGEKPFECKHCGKAFSCHSSLREHVRTHSGEKPY 464



 Score = 57.8 bits (138), Expect = 5e-08
 Identities = 21/51 (41%), Positives = 32/51 (62%)

Query: 373 HKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRH 423
           ++C  C K +   S+L++H+R+HTGERPY+C  CG  F    +L+ H   H
Sbjct: 492 YECTECGKAYSCSSSLRVHVRTHTGERPYECKQCGKTFRYLASLQAHVRTH 542



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 28/86 (32%), Positives = 39/86 (45%), Gaps = 4/86 (4%)

Query: 630 PNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARA 689
           P +C  C +  S  +  + H   H G +P++C  CG+A+S   +LR H   H        
Sbjct: 463 PYECNQCGKAFSHAQYFQKHVRSHSGVKPYECTECGKAYSCSSSLRVHVRTH----TGER 518

Query: 690 QNSCPICQKKFTNAVTLQQHVRMHLG 715
              C  C K F    +LQ HVR H G
Sbjct: 519 PYECKQCGKTFRYLASLQAHVRTHAG 544



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 22/57 (38%), Positives = 34/57 (59%)

Query: 374 KCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPHV 430
           +C+ C K F   S+L+ H R+H+GE+PY+C  CG  F    +L+ H   H  + P+V
Sbjct: 325 QCKHCGKAFTCYSSLREHGRTHSGEKPYECKECGKAFRYPSSLRAHMRMHTGEKPYV 381



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 24/63 (38%), Positives = 36/63 (57%), Gaps = 3/63 (4%)

Query: 367 EKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREK 426
           EKP    +C+ C K F   S+L+ H+R+H+GE+PY+CN CG  F+     + H   H   
Sbjct: 433 EKP---FECKHCGKAFSCHSSLREHVRTHSGEKPYECNQCGKAFSHAQYFQKHVRSHSGV 489

Query: 427 YPH 429
            P+
Sbjct: 490 KPY 492



 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 24/63 (38%), Positives = 37/63 (58%), Gaps = 3/63 (4%)

Query: 367 EKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREK 426
           EKP   ++C+ C K F   S+ + H+R+HTGE+P +C  CG  FT   +L+ H   H  +
Sbjct: 293 EKP---YECKHCGKSFSCYSSFRDHVRTHTGEKPCQCKHCGKAFTCYSSLREHGRTHSGE 349

Query: 427 YPH 429
            P+
Sbjct: 350 KPY 352



 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 23/63 (36%), Positives = 35/63 (55%), Gaps = 3/63 (4%)

Query: 367 EKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREK 426
           EKP   ++C  C K F      Q H+RSH+G +PY+C  CG  ++   +L+VH   H  +
Sbjct: 461 EKP---YECNQCGKAFSHAQYFQKHVRSHSGVKPYECTECGKAYSCSSSLRVHVRTHTGE 517

Query: 427 YPH 429
            P+
Sbjct: 518 RPY 520



 Score = 54.3 bits (129), Expect = 6e-07
 Identities = 22/57 (38%), Positives = 31/57 (54%)

Query: 373 HKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPH 429
           H C+ C K F   S L  H+R+HTGE+PY+C  CG  F+     + H   H  + P+
Sbjct: 240 HACKVCGKTFMYYSYLTRHVRTHTGEKPYECKECGKAFSCPSYFREHVRTHTGEKPY 296



 Score = 54.3 bits (129), Expect = 6e-07
 Identities = 23/62 (37%), Positives = 35/62 (56%), Gaps = 3/62 (4%)

Query: 367 EKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREK 426
           EKP   ++C+ C K F   S  + H+R+HTGE+PY+C  CG  F+   + + H   H  +
Sbjct: 265 EKP---YECKECGKAFSCPSYFREHVRTHTGEKPYECKHCGKSFSCYSSFRDHVRTHTGE 321

Query: 427 YP 428
            P
Sbjct: 322 KP 323



 Score = 53.9 bits (128), Expect = 7e-07
 Identities = 30/100 (30%), Positives = 40/100 (40%), Gaps = 4/100 (4%)

Query: 616 TTSAPAPSSSASSGPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLR 675
           T S     S +S    +C  C +   CP + R H   H G++   CKVCG+ F     L 
Sbjct: 197 TASVTYVKSLSSKKSYECQKCGKAFICPSSFRGHVNSHHGQKTHACKVCGKTFMYYSYLT 256

Query: 676 AHFVGHKASPAARAQNSCPICQKKFTNAVTLQQHVRMHLG 715
            H   H           C  C K F+     ++HVR H G
Sbjct: 257 RHVRTH----TGEKPYECKECGKAFSCPSYFREHVRTHTG 292



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 20/62 (32%), Positives = 36/62 (58%), Gaps = 3/62 (4%)

Query: 367 EKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREK 426
           EKP   + C+ C K FG  +  + H+++H+G +PY+C  CG  ++   +L++H   H  +
Sbjct: 377 EKP---YVCKQCGKAFGCPTYFRRHVKTHSGVKPYQCKECGKAYSFSSSLRIHVRTHTGE 433

Query: 427 YP 428
            P
Sbjct: 434 KP 435



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 24/63 (38%), Positives = 33/63 (52%), Gaps = 3/63 (4%)

Query: 367 EKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREK 426
           EKP   ++C+ C K F   S+L+ H+R HTGE+PY C  CG  F      + H   H   
Sbjct: 349 EKP---YECKECGKAFRYPSSLRAHMRMHTGEKPYVCKQCGKAFGCPTYFRRHVKTHSGV 405

Query: 427 YPH 429
            P+
Sbjct: 406 KPY 408



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 18/57 (31%), Positives = 29/57 (50%)

Query: 373 HKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPH 429
           ++C+ C K F   S+ + H+ SH G++ + C VCG  F     L  H   H  + P+
Sbjct: 212 YECQKCGKAFICPSSFRGHVNSHHGQKTHACKVCGKTFMYYSYLTRHVRTHTGEKPY 268



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 24/75 (32%), Positives = 41/75 (54%), Gaps = 4/75 (5%)

Query: 895 SLQEAMRKEPGESSSRKACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERAT 954
           S ++ +R   GE   +  C+ CG+AF   ++L EH +TH  E P + C  C + F   ++
Sbjct: 310 SFRDHVRTHTGEKPCQ--CKHCGKAFTCYSSLREHGRTHSGEKP-YECKECGKAFRYPSS 366

Query: 955 LKKHMLLAHHQVQPF 969
           L+ HM + H   +P+
Sbjct: 367 LRAHMRM-HTGEKPY 380



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 25/75 (33%), Positives = 39/75 (52%), Gaps = 4/75 (5%)

Query: 895 SLQEAMRKEPGESSSRKACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERAT 954
           SL+  +R   GE      C+ CG+AF   ++L EH +TH  E P + C  C + F     
Sbjct: 422 SLRIHVRTHTGEKPFE--CKHCGKAFSCHSSLREHVRTHSGEKP-YECNQCGKAFSHAQY 478

Query: 955 LKKHMLLAHHQVQPF 969
            +KH + +H  V+P+
Sbjct: 479 FQKH-VRSHSGVKPY 492



 Score = 37.0 bits (84), Expect = 0.093
 Identities = 16/47 (34%), Positives = 28/47 (59%), Gaps = 1/47 (2%)

Query: 913 CEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHM 959
           C+ CG+A+   ++L  H +TH  E P F C  C + F   ++L++H+
Sbjct: 410 CKECGKAYSFSSSLRIHVRTHTGEKP-FECKHCGKAFSCHSSLREHV 455



 Score = 34.7 bits (78), Expect = 0.46
 Identities = 18/62 (29%), Positives = 32/62 (51%), Gaps = 3/62 (4%)

Query: 897 QEAMRKEPGESSSRKACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLK 956
           +E +R   GE      C+ CG++F   ++  +H +TH  E P   C  C + F   ++L+
Sbjct: 284 REHVRTHTGEKPYE--CKHCGKSFSCYSSFRDHVRTHTGEKPC-QCKHCGKAFTCYSSLR 340

Query: 957 KH 958
           +H
Sbjct: 341 EH 342



 Score = 34.3 bits (77), Expect = 0.61
 Identities = 15/47 (31%), Positives = 25/47 (53%), Gaps = 1/47 (2%)

Query: 913 CEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHM 959
           C+ CG+AF   +   EH +TH  E P + C  C + F   ++ + H+
Sbjct: 270 CKECGKAFSCPSYFREHVRTHTGEKP-YECKHCGKSFSCYSSFRDHV 315



 Score = 34.3 bits (77), Expect = 0.61
 Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 1/47 (2%)

Query: 913 CEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHM 959
           C  CG+A+   ++L  H +TH  E P + C  C + F   A+L+ H+
Sbjct: 494 CTECGKAYSCSSSLRVHVRTHTGERP-YECKQCGKTFRYLASLQAHV 539



 Score = 33.9 bits (76), Expect = 0.79
 Identities = 16/48 (33%), Positives = 26/48 (54%), Gaps = 1/48 (2%)

Query: 912 ACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHM 959
           AC+VCG+ F   + L  H +TH  E P + C  C + F   +  ++H+
Sbjct: 241 ACKVCGKTFMYYSYLTRHVRTHTGEKP-YECKECGKAFSCPSYFREHV 287



 Score = 33.9 bits (76), Expect = 0.79
 Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 4/75 (5%)

Query: 895 SLQEAMRKEPGESSSRKACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERAT 954
           SL+  MR   GE      C+ CG+AF        H KTH    P + C  C + +   ++
Sbjct: 366 SLRAHMRMHTGEKPY--VCKQCGKAFGCPTYFRRHVKTHSGVKP-YQCKECGKAYSFSSS 422

Query: 955 LKKHMLLAHHQVQPF 969
           L+ H +  H   +PF
Sbjct: 423 LRIH-VRTHTGEKPF 436


>gi|37693995 Kruppel-like factor 13 [Homo sapiens]
          Length = 288

 Score = 71.6 bits (174), Expect = 3e-12
 Identities = 47/136 (34%), Positives = 59/136 (43%), Gaps = 23/136 (16%)

Query: 298 PTPAPSPALPGSTDQLIASPHLAFPSTTGLLAAQCLGAARGLEATASPGLLKPKNGSGE- 356
           P PAP P  PG+     A P  A+                GLE    PG      GSGE 
Sbjct: 99  PPPAPEPTSPGAEGAAAAPPSPAWSEPE---------PEAGLEPEREPG----PAGSGEP 145

Query: 357 -----LSYGEVMGPLEKPGGRHKCRF--CAKVFGSDSALQIHLRSHTGERPYKCN--VCG 407
                +  G     LE P  +HKC +  C KV+G  S L+ HLR+HTGERP+ C+   C 
Sbjct: 146 GLRQRVRRGRSRADLESPQRKHKCHYAGCEKVYGKSSHLKAHLRTHTGERPFACSWQDCN 205

Query: 408 NRFTTRGNLKVHFHRH 423
            +F     L  H+  H
Sbjct: 206 KKFARSDELARHYRTH 221



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 33/107 (30%), Positives = 48/107 (44%), Gaps = 9/107 (8%)

Query: 636 CLRVLSCPRALRLHYGQHGGERPFKC--KVCGRAFSTRGNLRAHFVGHKASPAARAQNSC 693
           C +V      L+ H   H GERPF C  + C + F+    L  H+  H        + SC
Sbjct: 174 CEKVYGKSSHLKAHLRTHTGERPFACSWQDCNKKFARSDELARHYRTH----TGEKKFSC 229

Query: 694 PICQKKFTNAVTLQQHVRMHLGGQIPNGGTALPEGGGAAQENGSEQS 740
           PIC+K+F  +  L +H R H      + G     GGG+   + S+ S
Sbjct: 230 PICEKRFMRSDHLTKHARRHANF---HPGMLQRRGGGSRTGSLSDYS 273


>gi|148276990 zinc finger and BTB domain containing 38 [Homo sapiens]
          Length = 1195

 Score = 71.2 bits (173), Expect = 4e-12
 Identities = 35/94 (37%), Positives = 48/94 (51%), Gaps = 4/94 (4%)

Query: 622  PSSSASSGPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGH 681
            P    +S P  C +C +    P  L++H   H GE+P++CK CGR FS +GNL+ H   H
Sbjct: 1001 PHRHLTSRPYACELCAKQFQSPSTLKMHMRCHTGEKPYQCKTCGRCFSVQGNLQKHERIH 1060

Query: 682  KASPAARAQNSCPICQKKFTNAVTLQQHVRMHLG 715
                    +  C  C K FT   TL+ H R+H G
Sbjct: 1061 ----LGLKEFVCQYCNKAFTLNETLKIHERIHTG 1090



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 25/51 (49%), Positives = 34/51 (66%)

Query: 373  HKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRH 423
            + C  CAK F S S L++H+R HTGE+PY+C  CG  F+ +GNL+ H   H
Sbjct: 1010 YACELCAKQFQSPSTLKMHMRCHTGEKPYQCKTCGRCFSVQGNLQKHERIH 1060



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 135/638 (21%), Positives = 223/638 (34%), Gaps = 93/638 (14%)

Query: 373  HKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVH---FHR--HR--- 424
            + C +C KVF        H   HTGER Y+C  C   F T   LK H   FH   HR   
Sbjct: 488  YPCHYCNKVFALAEYRTRHEIWHTGERRYQCIFCLETFMTYYILKNHQKSFHAIDHRLSI 547

Query: 425  -EKYPHVQMNPHPVPEHLDYVITSS--GLPY------GMSVPPEKAEEEAATPGGGVERK 475
             +K  +  + P   P  L  ++       PY            E ++   + PG  V + 
Sbjct: 548  SKKTANGGLKPSVYPYKLYRLLPMKCKRAPYKSYRNSSYENARENSQMNESAPGTYVVQN 607

Query: 476  PLVASTTALSATESLTLLSTSAGTATAPGLPAFNKFVLMKAVEPKNKADENTPPGSEGSA 535
            P  +    L+  +++  L+ S      P +P               +  E T  G E   
Sbjct: 608  PHSSELPTLNFQDTVNTLTNS------PAIPLETSACQDIPTSANVQNAEGTKWGEEALK 661

Query: 536  I--------SGVAESSTATRMQLSKLVTSLPSWALLTNHFKSTGSFPFPYVLEPLGASPS 587
            +        + V+ SST   +        +P  +L +N  ++  S     V+   G++PS
Sbjct: 662  MDLDNNFYSTEVSVSSTENAVSSDLRAGDVPVLSL-SNSSENAAS-----VISYSGSAPS 715

Query: 588  ETSKLQQLVEKIDRQGAVA-VTSAASGAPTTSAPAPSSSASSGPNQCVICLRVLSCPRAL 646
                  Q    I    A+A +TS+   A +  A + S    S P    +  R  S P+++
Sbjct: 716  VIVHSSQFSSVIMHSNAIAAMTSSNHRAFSDPAVSQSLKDDSKPEPDKVG-RFASRPKSI 774

Query: 647  RLHY---GQHGGERPFKCKVC---GRAFSTRGNLRAH------FVGHKASPAARAQ-NSC 693
            +          GE P +       G + S   N+         ++   A P      N  
Sbjct: 775  KEKKKTTSHTRGEIPEESNYVADPGGSLSKTTNIAEETSKIETYIAKPALPGTSTNSNVA 834

Query: 694  PICQ--KKFTNAVTLQQHVRMHLGGQIPNGGTALPEGGGAAQENGSEQSTVSGAGSFPQQ 751
            P+CQ   K  N   +++H+          G     + G   +    E+    G    P  
Sbjct: 835  PLCQITVKIGNEAIVKRHIL---------GSKLFYKRGRRPKYQMQEEPLPQGNDPEPSG 885

Query: 752  QSQQPSPEEELSEEEEEEDEEEEEDVTDED-------SLAGRGSESGGEKAISVRGDSEE 804
             S     + E  E  E  D+  ++D TD+            +  +    + ++ R +   
Sbjct: 886  DSPLGLCQSECMEMSEVFDDASDQDSTDKPWRPYYNYKPKKKSRQLKKMRKVNWRKEHGN 945

Query: 805  ASGAEEEVGTVAAAATAGKEMDSNEKTTQQSSLPPPPPPDSLDQPQPMEQGSSGVLGGKE 864
             S + +           GK         +++   P    +  D       G   V  G +
Sbjct: 946  RSPSHKCKYPAELDCAVGKAPQDKPFEEEETKEMPKLQCELCD-------GDKAVGAGNQ 998

Query: 865  EGGKPER--SSSPASALTPEGEATSVTLVEELSLQEAMRKEPGESSSRKACEVCGQAFPS 922
              G+P R  +S P +      E  +       +L+  MR   GE   +  C+ CG+ F  
Sbjct: 999  --GRPHRHLTSRPYAC-----ELCAKQFQSPSTLKMHMRCHTGEKPYQ--CKTCGRCFSV 1049

Query: 923  QAALEEHQKTH--PKEGPLFTCVFCRQGFLERATLKKH 958
            Q  L++H++ H   KE   F C +C + F    TLK H
Sbjct: 1050 QGNLQKHERIHLGLKE---FVCQYCNKAFTLNETLKIH 1084



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 20/49 (40%), Positives = 26/49 (53%)

Query: 375  CRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRH 423
            C++C K F  +  L+IH R HTGE+ Y C  C  RF      + H  RH
Sbjct: 1068 CQYCNKAFTLNETLKIHERIHTGEKRYHCQFCFQRFLYLSTKRNHEQRH 1116



 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 24/66 (36%), Positives = 31/66 (46%), Gaps = 4/66 (6%)

Query: 367  EKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHR-E 425
            EKP   ++C+ C + F     LQ H R H G + + C  C   FT    LK+H   H  E
Sbjct: 1035 EKP---YQCKTCGRCFSVQGNLQKHERIHLGLKEFVCQYCNKAFTLNETLKIHERIHTGE 1091

Query: 426  KYPHVQ 431
            K  H Q
Sbjct: 1092 KRYHCQ 1097



 Score = 38.9 bits (89), Expect = 0.025
 Identities = 46/188 (24%), Positives = 72/188 (38%), Gaps = 34/188 (18%)

Query: 252 KTLASSSSSSSSSSGAETPKQAFFHLYHPLGSQHPFSAGGVGRSH------KPTPAPSP- 304
           +TLA  S + SS + A        +   P+      S G  G+ +      KP     P 
Sbjct: 216 RTLAEHSYAVSSVAEA--------YRSQPVREHDGSSPGNTGKENCEALAAKPKTCRKPK 267

Query: 305 --ALPGSTDQLIASPHLAFPSTTGLLAAQCLGAARGLEATASPGLLKPKNGSGELSYG-- 360
             ++P  +D   A+ ++  P  + L   Q     R  +  A     K  N  G++ +   
Sbjct: 268 TFSIPQDSDS--ATENIPPPPVSNLEVNQ----ERSPQPAAVLTRSKSPNNEGDVHFSRE 321

Query: 361 ------EVMGP--LEKPGGRHKCRFCAKVFGSDSALQIHLRSH-TGERPYKCNVCGNRFT 411
                 +V GP   E P   + C  C+K F S + L  H++ H   + P  C  C  +FT
Sbjct: 322 DENQSSDVPGPPAAEVPPLVYNCSCCSKAFDSSTLLSAHMQLHKPTQEPLVCKYCNKQFT 381

Query: 412 TRGNLKVH 419
           T   L  H
Sbjct: 382 TLNRLDRH 389



 Score = 36.6 bits (83), Expect = 0.12
 Identities = 23/98 (23%), Positives = 35/98 (35%), Gaps = 12/98 (12%)

Query: 633 CVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARAQNS 692
           CV+C R      +LR H   H   R + C  C + F+       H + H        +  
Sbjct: 462 CVVCKRSYVTLSSLRRHANVHSWRRTYPCHYCNKVFALAEYRTRHEIWH----TGERRYQ 517

Query: 693 CPICQKKFTNAVTLQQHV--------RMHLGGQIPNGG 722
           C  C + F     L+ H         R+ +  +  NGG
Sbjct: 518 CIFCLETFMTYYILKNHQKSFHAIDHRLSISKKTANGG 555



 Score = 35.8 bits (81), Expect = 0.21
 Identities = 21/82 (25%), Positives = 32/82 (39%), Gaps = 1/82 (1%)

Query: 633  CVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARAQNS 692
            C  C +  +    L++H   H GE+ + C+ C + F      R H   H      +   +
Sbjct: 1068 CQYCNKAFTLNETLKIHERIHTGEKRYHCQFCFQRFLYLSTKRNHEQRHIREHNGKGY-A 1126

Query: 693  CPICQKKFTNAVTLQQHVRMHL 714
            C  C K    A  L  H + HL
Sbjct: 1127 CFQCPKICKTAAALGMHQKKHL 1148



 Score = 35.4 bits (80), Expect = 0.27
 Identities = 36/144 (25%), Positives = 50/144 (34%), Gaps = 27/144 (18%)

Query: 839 PPPPPDSLDQPQPMEQGSSGVLGGKEEGGKPERSSSPASALTPEGEATSVTLVEELSLQE 898
           PPPP  +L+  Q                   ERS  PA+ LT      +   V      E
Sbjct: 283 PPPPVSNLEVNQ-------------------ERSPQPAAVLTRSKSPNNEGDVHFSREDE 323

Query: 899 AMRKE-PGESSSRKA-----CEVCGQAFPSQAALEEHQKTH-PKEGPLFTCVFCRQGFLE 951
               + PG  ++        C  C +AF S   L  H + H P + PL  C +C + F  
Sbjct: 324 NQSSDVPGPPAAEVPPLVYNCSCCSKAFDSSTLLSAHMQLHKPTQEPL-VCKYCNKQFTT 382

Query: 952 RATLKKHMLLAHHQVQPFAPHGPQ 975
              L +H  +         P G Q
Sbjct: 383 LNRLDRHEQICMRSSHMPIPGGNQ 406



 Score = 35.4 bits (80), Expect = 0.27
 Identities = 33/128 (25%), Positives = 45/128 (35%), Gaps = 22/128 (17%)

Query: 659 FKCKVCGRAFSTRGNLRAHFVGHKASPAARAQNSCPICQKKFTNAVTLQQHVRMHLGGQ- 717
           + C  C +AF +   L AH   HK +        C  C K+FT    L +H ++ +    
Sbjct: 342 YNCSCCSKAFDSSTLLSAHMQLHKPTQEPLV---CKYCNKQFTTLNRLDRHEQICMRSSH 398

Query: 718 --IPNGGTALPEGGGAAQENGSEQSTVSGAGSFPQQQSQQPSPEEELSEEEEEEDEEEEE 775
             IP G     E      +NG         GSF         PE  LSE    E      
Sbjct: 399 MPIPGGNQRFLENYPTIGQNG---------GSF-------TGPEPLLSENRIGEFSSTGS 442

Query: 776 DVTDEDSL 783
            + D D +
Sbjct: 443 TLPDTDHM 450



 Score = 34.3 bits (77), Expect = 0.61
 Identities = 16/46 (34%), Positives = 24/46 (52%), Gaps = 1/46 (2%)

Query: 913  CEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKH 958
            C+ C +AF     L+ H++ H  E   + C FC Q FL  +T + H
Sbjct: 1068 CQYCNKAFTLNETLKIHERIHTGE-KRYHCQFCFQRFLYLSTKRNH 1112



 Score = 31.2 bits (69), Expect = 5.1
 Identities = 19/61 (31%), Positives = 26/61 (42%), Gaps = 4/61 (6%)

Query: 655 GERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARAQNSCPICQKKFTNAVTLQQHVRMHL 714
           G+  + C VC R++ T  +LR H   H    + R    C  C K F  A    +H   H 
Sbjct: 456 GQMLYSCVVCKRSYVTLSSLRRHANVH----SWRRTYPCHYCNKVFALAEYRTRHEIWHT 511

Query: 715 G 715
           G
Sbjct: 512 G 512


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.128    0.377 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 52,528,851
Number of Sequences: 37866
Number of extensions: 3361631
Number of successful extensions: 114579
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1938
Number of HSP's successfully gapped in prelim test: 1207
Number of HSP's that attempted gapping in prelim test: 31707
Number of HSP's gapped (non-prelim): 52175
length of query: 1007
length of database: 18,247,518
effective HSP length: 112
effective length of query: 895
effective length of database: 14,006,526
effective search space: 12535840770
effective search space used: 12535840770
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.