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Search of human proteins with 4758508
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4758508 transmembrane protease, serine 11D [Homo sapiens]
(418 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4758508 transmembrane protease, serine 11D [Homo sapiens] 850 0.0
gi|167466252 transmembrane protease, serine 11A isoform 2 [Homo ... 354 9e-98
gi|167466250 transmembrane protease, serine 11A isoform 1 [Homo ... 350 2e-96
gi|194018492 transmembrane protease, serine 11F [Homo sapiens] 333 1e-91
gi|40254871 transmembrane protease, serine 11E [Homo sapiens] 330 1e-90
gi|153791781 transmembrane protease, serine 11E2 [Homo sapiens] 330 1e-90
gi|187761337 transmembrane protease, serine 11B [Homo sapiens] 315 6e-86
gi|33695155 hepsin [Homo sapiens] 213 3e-55
gi|4504481 hepsin [Homo sapiens] 213 3e-55
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap... 210 2e-54
gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo sa... 209 3e-54
gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo sap... 209 4e-54
gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo sa... 204 1e-52
gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo sa... 204 1e-52
gi|205360905 testis-specific serine protease 1 [Homo sapiens] 197 2e-50
gi|170932492 transmembrane protease, serine 5 [Homo sapiens] 194 1e-49
gi|11415040 matriptase [Homo sapiens] 194 2e-49
gi|33667063 transmembrane protease, serine 9 [Homo sapiens] 194 2e-49
gi|223942069 enterokinase precursor [Homo sapiens] 191 1e-48
gi|23957702 transmembrane protease, serine 6 [Homo sapiens] 191 1e-48
gi|148613878 acrosin precursor [Homo sapiens] 189 4e-48
gi|21614531 testisin isoform 2 [Homo sapiens] 188 7e-48
gi|78191798 plasma kallikrein B1 precursor [Homo sapiens] 187 2e-47
gi|5803197 testisin isoform 1 [Homo sapiens] 186 3e-47
gi|4506153 prostasin preproprotein [Homo sapiens] 186 4e-47
gi|116256363 transmembrane protease, serine 13 [Homo sapiens] 185 6e-47
gi|4503627 coagulation factor XI precursor [Homo sapiens] 184 1e-46
gi|32698940 transmembrane protease, serine 12 [Homo sapiens] 184 1e-46
gi|117956391 protease, serine, 33 [Homo sapiens] 182 4e-46
gi|110815798 ovochymase 1 [Homo sapiens] 182 6e-46
>gi|4758508 transmembrane protease, serine 11D [Homo sapiens]
Length = 418
Score = 850 bits (2197), Expect = 0.0
Identities = 418/418 (100%), Positives = 418/418 (100%)
Query: 1 MYRPARVTSTSRFLNPYVVCFIVVAGVVILAVTIALLVYFLAFDQKSYFYRSSFQLLNVE 60
MYRPARVTSTSRFLNPYVVCFIVVAGVVILAVTIALLVYFLAFDQKSYFYRSSFQLLNVE
Sbjct: 1 MYRPARVTSTSRFLNPYVVCFIVVAGVVILAVTIALLVYFLAFDQKSYFYRSSFQLLNVE 60
Query: 61 YNSQLNSPATQEYRTLSGRIESLITKTFKESNLRNQFIRAHVAKLRQDGSGVRADVVMKF 120
YNSQLNSPATQEYRTLSGRIESLITKTFKESNLRNQFIRAHVAKLRQDGSGVRADVVMKF
Sbjct: 61 YNSQLNSPATQEYRTLSGRIESLITKTFKESNLRNQFIRAHVAKLRQDGSGVRADVVMKF 120
Query: 121 QFTRNNNGASMKSRIESVLRQMLNNSGNLEINPSTEITSLTDQAAANWLINECGAGPDLI 180
QFTRNNNGASMKSRIESVLRQMLNNSGNLEINPSTEITSLTDQAAANWLINECGAGPDLI
Sbjct: 121 QFTRNNNGASMKSRIESVLRQMLNNSGNLEINPSTEITSLTDQAAANWLINECGAGPDLI 180
Query: 181 TLSEQRILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCFRSNSNPRDWIA 240
TLSEQRILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCFRSNSNPRDWIA
Sbjct: 181 TLSEQRILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCFRSNSNPRDWIA 240
Query: 241 TSGISTTFPKLRMRVRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSVCLPAATQNI 300
TSGISTTFPKLRMRVRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSVCLPAATQNI
Sbjct: 241 TSGISTTFPKLRMRVRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSVCLPAATQNI 300
Query: 301 PPGSTAYVTGWGAQEYAGHTVPELRQGQVRIISNDVCNAPHSYNGAILSGMLCAGVPQGG 360
PPGSTAYVTGWGAQEYAGHTVPELRQGQVRIISNDVCNAPHSYNGAILSGMLCAGVPQGG
Sbjct: 301 PPGSTAYVTGWGAQEYAGHTVPELRQGQVRIISNDVCNAPHSYNGAILSGMLCAGVPQGG 360
Query: 361 VDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQCGLPDKPGVYTRVTAYLDWIRQQTGI 418
VDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQCGLPDKPGVYTRVTAYLDWIRQQTGI
Sbjct: 361 VDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQCGLPDKPGVYTRVTAYLDWIRQQTGI 418
>gi|167466252 transmembrane protease, serine 11A isoform 2 [Homo
sapiens]
Length = 418
Score = 354 bits (908), Expect = 9e-98
Identities = 168/418 (40%), Positives = 250/418 (59%), Gaps = 1/418 (0%)
Query: 1 MYRPARVTSTSRFLNPYVVCFIVVAGVVILAVTIALLVYFLAFDQKSYFYRSSFQLLNVE 60
MYR + SR L P+++ ++V + ++AVTI LLV+FL FDQK +Y SF++L+ +
Sbjct: 2 MYRTVGFGTRSRNLKPWMIAVLIVLSLTVVAVTIGLLVHFLVFDQKKEYYHGSFKILDPQ 61
Query: 61 YNSQLNSPATQEYRTLSGRIESLITKTFKESNLRNQFIRAHVAKLRQDGSGVRADVVMKF 120
N+ T + + L E+L+ + F +S + +I+ V +L + GV+ DV+M F
Sbjct: 62 INNNFGQSNTYQLKDLRETTENLVDEIFIDSAWKKNYIKNQVVRLTPEEDGVKVDVIMVF 121
Query: 121 QFTRNNNGASMKSRIESVLRQMLNNSGNLEINPSTEITSLTDQAAANWLINECGAGPDLI 180
QF A + +I+S+L Q + N L IN S+ + + + + G ++
Sbjct: 122 QFPSTEQRAVREKKIQSILNQKIRNLRALPINASSVQVNAMSSSTGELTV-QASCGKRVV 180
Query: 181 TLSEQRILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCFRSNSNPRDWIA 240
L+ RI G A + +WPWQ SL+ +N H CG +LI+N W++TAAHCF+ NP W
Sbjct: 181 PLNVNRIASGVIAPKAAWPWQASLQYDNIHQCGATLISNTWLVTAAHCFQKYKNPHQWTV 240
Query: 241 TSGISTTFPKLRMRVRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSVCLPAATQNI 300
+ G P ++ VR +IH Y+SA E DIA+V++ + VTF+ DI +CLP A+ +
Sbjct: 241 SFGTKINPPLMKRNVRRFIIHEKYRSAAREYDIAVVQVSSRVTFSDDIRQICLPEASASF 300
Query: 301 PPGSTAYVTGWGAQEYAGHTVPELRQGQVRIISNDVCNAPHSYNGAILSGMLCAGVPQGG 360
P T ++TG+GA Y G + +LR+ +V+IIS+DVC P Y I GM CAG +G
Sbjct: 301 QPNLTVHITGFGALYYGGESQNDLREARVKIISDDVCKQPQVYGNDIKPGMFCAGYMEGI 360
Query: 361 VDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQCGLPDKPGVYTRVTAYLDWIRQQTGI 418
DAC+GDSGGPLV D + W+++GIVSWGD CG DKPGVYT+VT Y +WI +TGI
Sbjct: 361 YDACRGDSGGPLVTRDLKDTWYLIGIVSWGDNCGQKDKPGVYTQVTYYRNWIASKTGI 418
>gi|167466250 transmembrane protease, serine 11A isoform 1 [Homo
sapiens]
Length = 421
Score = 350 bits (897), Expect = 2e-96
Identities = 168/421 (39%), Positives = 251/421 (59%), Gaps = 4/421 (0%)
Query: 1 MYRPARVTSTSRFLNPYVVCFIVVAGVVILAVTIALLVYFLAFDQKSYFYRSSFQLLNVE 60
MYR + SR L P+++ ++V + ++AVTI LLV+FL FDQK +Y SF++L+ +
Sbjct: 2 MYRTVGFGTRSRNLKPWMIAVLIVLSLTVVAVTIGLLVHFLVFDQKKEYYHGSFKILDPQ 61
Query: 61 YNSQLNSPATQEYRTLSGRIESLITKT---FKESNLRNQFIRAHVAKLRQDGSGVRADVV 117
N+ T + + L E+L+++ F +S + +I+ V +L + GV+ DV+
Sbjct: 62 INNNFGQSNTYQLKDLRETTENLVSQVDEIFIDSAWKKNYIKNQVVRLTPEEDGVKVDVI 121
Query: 118 MKFQFTRNNNGASMKSRIESVLRQMLNNSGNLEINPSTEITSLTDQAAANWLINECGAGP 177
M FQF A + +I+S+L Q + N L IN S+ + + + + G
Sbjct: 122 MVFQFPSTEQRAVREKKIQSILNQKIRNLRALPINASSVQVNAMSSSTGELTV-QASCGK 180
Query: 178 DLITLSEQRILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCFRSNSNPRD 237
++ L+ RI G A + +WPWQ SL+ +N H CG +LI+N W++TAAHCF+ NP
Sbjct: 181 RVVPLNVNRIASGVIAPKAAWPWQASLQYDNIHQCGATLISNTWLVTAAHCFQKYKNPHQ 240
Query: 238 WIATSGISTTFPKLRMRVRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSVCLPAAT 297
W + G P ++ VR +IH Y+SA E DIA+V++ + VTF+ DI +CLP A+
Sbjct: 241 WTVSFGTKINPPLMKRNVRRFIIHEKYRSAAREYDIAVVQVSSRVTFSDDIRQICLPEAS 300
Query: 298 QNIPPGSTAYVTGWGAQEYAGHTVPELRQGQVRIISNDVCNAPHSYNGAILSGMLCAGVP 357
+ P T ++TG+GA Y G + +LR+ +V+IIS+DVC P Y I GM CAG
Sbjct: 301 ASFQPNLTVHITGFGALYYGGESQNDLREARVKIISDDVCKQPQVYGNDIKPGMFCAGYM 360
Query: 358 QGGVDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQCGLPDKPGVYTRVTAYLDWIRQQTG 417
+G DAC+GDSGGPLV D + W+++GIVSWGD CG DKPGVYT+VT Y +WI +TG
Sbjct: 361 EGIYDACRGDSGGPLVTRDLKDTWYLIGIVSWGDNCGQKDKPGVYTQVTYYRNWIASKTG 420
Query: 418 I 418
I
Sbjct: 421 I 421
>gi|194018492 transmembrane protease, serine 11F [Homo sapiens]
Length = 438
Score = 333 bits (855), Expect = 1e-91
Identities = 175/417 (41%), Positives = 254/417 (60%), Gaps = 11/417 (2%)
Query: 12 RFLNPYVVCFIVVAGVVILAVTIALLVYFLAFDQKSYFYRSSFQLLNVEYNSQLNSPATQ 71
+F + + +A V I+ + I ++ +F+ D KS++Y +SF++ N++Y +++
Sbjct: 23 QFWDSVRLALFTLAIVAIIGIAIGIVTHFVVEDDKSFYYLASFKVTNIKYKENYGIRSSR 82
Query: 72 EYRTLSGRIESLITKTFKESNLRNQFIRAHVAKLRQDGSGVRADVVMKFQFTRNNNGASM 131
E+ S +IE ++++ F+ S++ +FI++HV KL D GV +V+ F++ ++ +
Sbjct: 83 EFIERSHQIERMMSRIFRHSSVGGRFIKSHVIKLSPDEQGVDILIVLIFRYPSTDSAEQI 142
Query: 132 KSRIESVLRQMLNNSG-NLEIN-PSTEITSLTDQAAANWLINECGAG------PDLITLS 183
K +IE L Q L +L IN PS +T + + N L + CG P + S
Sbjct: 143 KKKIEKALYQSLKTKQLSLTINKPSFRLTPIDSKKMRNLLNSRCGIRMTSSNMPLPASSS 202
Query: 184 EQRILGGTE-AEEGSWPWQVSLRL-NNAHHCGGSLINNMWILTAAHCFRSNSNPRDWIAT 241
QRI+ G E A EG WPWQ SL+L + H CG SLI+N W+LTAAHCF N +P WIAT
Sbjct: 203 TQRIVQGRETAMEGEWPWQASLQLIGSGHQCGASLISNTWLLTAAHCFWKNKDPTQWIAT 262
Query: 242 SGISTTFPKLRMRVRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSVCLPAATQNIP 301
G + T P ++ VR I++H NY T+ENDIALV+L V F+ + VCLP ++ +P
Sbjct: 263 FGATITPPAVKRNVRKIILHENYHRETNENDIALVQLSTGVEFSNIVQRVCLPDSSIKLP 322
Query: 302 PGSTAYVTGWGAQEYAGHTVPELRQGQVRIISNDVCNAPHSYNGAILSGMLCAGVPQGGV 361
P ++ +VTG+G+ G LRQ +V IS DVCN Y+G I GMLCAG +G +
Sbjct: 323 PKTSVFVTGFGSIVDDGPIQNTLRQARVETISTDVCNRKDVYDGLITPGMLCAGFMEGKI 382
Query: 362 DACQGDSGGPLVQEDSRRLWFIVGIVSWGDQCGLPDKPGVYTRVTAYLDWIRQQTGI 418
DAC+GDSGGPLV D+ +W+IVGIVSWG C LP KPGVYTRVT Y DWI +TG+
Sbjct: 383 DACKGDSGGPLVY-DNHDIWYIVGIVSWGQSCALPKKPGVYTRVTKYRDWIASKTGM 438
>gi|40254871 transmembrane protease, serine 11E [Homo sapiens]
Length = 423
Score = 330 bits (847), Expect = 1e-90
Identities = 164/422 (38%), Positives = 252/422 (59%), Gaps = 4/422 (0%)
Query: 1 MYRPARVTSTSRFL-NPYVVCFIVVAGVVILAVTIALLVYFLAFDQK-SYFYRSSFQLLN 58
MYRP V + R P+V+ ++ +++LAV I L V+++ ++QK +Y Y S+
Sbjct: 2 MYRPDVVRARKRVCWEPWVIGLVIFISLIVLAVCIGLTVHYVRYNQKKTYNYYSTLSFTT 61
Query: 59 VEYNSQLNSPATQEYRTLSGRIESLITKTFKESNLRNQFIRAHVAKLRQDGSGVRADVVM 118
+ ++ A+ + +S R+ES++ F +S LR +F+++ V K Q GV A +++
Sbjct: 62 DKLYAEFGREASNNFTEMSQRLESMVKNAFYKSPLREEFVKSQVIKFSQQKHGVLAHMLL 121
Query: 119 KFQFTRNNNGASMKSRIESVLRQMLNNS-GNLEINP-STEITSLTDQAAANWLINECGAG 176
+F + ++ ++ VL + L ++ G +++P S +I + ++L + CG
Sbjct: 122 ICRFHSTEDPETVDKIVQLVLHEKLQDAVGPPKVDPHSVKIKKINKTETDSYLNHCCGTR 181
Query: 177 PDLITLSEQRILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCFRSNSNPR 236
RI+GGTE EEG WPWQ SL+ + +H CG +LIN W+++AAHCF + NP
Sbjct: 182 RSKTLGQSLRIVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCFTTYKNPA 241
Query: 237 DWIATSGISTTFPKLRMRVRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSVCLPAA 296
W A+ G++ K++ +R I++H YK +H+ DI+L L + V +T +H VCLP A
Sbjct: 242 RWTASFGVTIKPSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDA 301
Query: 297 TQNIPPGSTAYVTGWGAQEYAGHTVPELRQGQVRIISNDVCNAPHSYNGAILSGMLCAGV 356
+ PG +VTG+GA + G++ LRQ QV +I CN P +YN AI MLCAG
Sbjct: 302 SYEFQPGDVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAYNDAITPRMLCAGS 361
Query: 357 PQGGVDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQCGLPDKPGVYTRVTAYLDWIRQQT 416
+G DACQGDSGGPLV D+R +W++ GIVSWGD+C P+KPGVYTRVTA DWI +T
Sbjct: 362 LEGKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKPGVYTRVTALRDWITSKT 421
Query: 417 GI 418
GI
Sbjct: 422 GI 423
>gi|153791781 transmembrane protease, serine 11E2 [Homo sapiens]
Length = 423
Score = 330 bits (847), Expect = 1e-90
Identities = 164/422 (38%), Positives = 252/422 (59%), Gaps = 4/422 (0%)
Query: 1 MYRPARVTSTSRFL-NPYVVCFIVVAGVVILAVTIALLVYFLAFDQK-SYFYRSSFQLLN 58
MYRP V + R P+V+ ++ +++LAV I L V+++ ++QK +Y Y S+
Sbjct: 2 MYRPDVVRARKRVCWEPWVIGLVIFISLIVLAVCIGLTVHYVRYNQKKTYNYYSTLSFTT 61
Query: 59 VEYNSQLNSPATQEYRTLSGRIESLITKTFKESNLRNQFIRAHVAKLRQDGSGVRADVVM 118
+ ++ A+ + +S R+ES++ F +S LR +F+++ V K Q GV A +++
Sbjct: 62 DKLYAEFGREASNNFTEMSQRLESMVKNAFYKSPLREEFVKSQVIKFSQQKHGVLAHMLL 121
Query: 119 KFQFTRNNNGASMKSRIESVLRQMLNNS-GNLEINP-STEITSLTDQAAANWLINECGAG 176
+F + ++ ++ VL + L ++ G +++P S +I + ++L + CG
Sbjct: 122 ICRFHSTEDPETVDKIVQLVLHEKLQDAVGPPKVDPQSVKIKKINKTETDSYLNHCCGTR 181
Query: 177 PDLITLSEQRILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCFRSNSNPR 236
RI+GGTE EEG WPWQ SL+ + +H CG +LIN W+++AAHCF + NP
Sbjct: 182 RSKTLGQSLRIVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCFTTYKNPA 241
Query: 237 DWIATSGISTTFPKLRMRVRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSVCLPAA 296
W A+ G++ K++ +R I++H YK +H+ DI+L L + V +T +H VCLP A
Sbjct: 242 RWTASFGVTIKPSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDA 301
Query: 297 TQNIPPGSTAYVTGWGAQEYAGHTVPELRQGQVRIISNDVCNAPHSYNGAILSGMLCAGV 356
+ PG +VTG+GA + G++ LRQ QV +I CN P +YN AI MLCAG
Sbjct: 302 SYEFQPGDVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAYNDAITPRMLCAGS 361
Query: 357 PQGGVDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQCGLPDKPGVYTRVTAYLDWIRQQT 416
+G DACQGDSGGPLV D+R +W++ GIVSWGD+C P+KPGVYTRVTA DWI +T
Sbjct: 362 LEGKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKPGVYTRVTALRDWITSKT 421
Query: 417 GI 418
GI
Sbjct: 422 GI 423
>gi|187761337 transmembrane protease, serine 11B [Homo sapiens]
Length = 416
Score = 315 bits (806), Expect = 6e-86
Identities = 165/420 (39%), Positives = 242/420 (57%), Gaps = 6/420 (1%)
Query: 1 MYRPARVTSTSRFLNPYVVCFIVVAGVVILAVTIALLVYFLAFDQKSYFYRSSFQLLNVE 60
MYR S+ R + FI + IL VTI LLV+FLA + K+Y+Y+ F + V
Sbjct: 1 MYRHG--ISSQRSWPLWTTIFIFLGVAAILGVTIGLLVHFLAVE-KTYYYQGDFHISGVT 57
Query: 61 YNSQLNSPATQEYRTLSGRIESLITKTFKESNLRNQFIRAHVAKLRQDGSGVRADVVMKF 120
YN + A+Q LS IE+ + F+ S++ +++++ V KL + +G + +KF
Sbjct: 58 YNDNCENAASQASTNLSKDIETKMLNAFQNSSIYKEYVKSEVIKLLPNANGSNVQLQLKF 117
Query: 121 QFTRNNNGASMKSRIESVLRQML-NNSGNLEINPSTEITSLTDQAAANWLINEC-GAGPD 178
+F G SM+++I++ L QML NN + P++ +AA+ L N C G
Sbjct: 118 KFPPAE-GVSMRTKIKAKLHQMLKNNMASWNAVPASIKLMEISKAASEMLTNNCCGRQVA 176
Query: 179 LITLSEQRILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCFRSNSNPRDW 238
++ +I+ G + EG+WPWQ S++ H+CG SLI++ W+L+AAHCF +N +DW
Sbjct: 177 NSIITGNKIVNGKSSLEGAWPWQASMQWKGRHYCGASLISSRWLLSAAHCFAKKNNSKDW 236
Query: 239 IATSGISTTFPKLRMRVRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSVCLPAATQ 298
GI P + +V+NI+ H NY S +DIALV+L V+FT+ I +CLP A
Sbjct: 237 TVNFGIVVNKPYMTRKVQNIIFHENYSSPGLHDDIALVQLAEEVSFTEYIRKICLPEAKM 296
Query: 299 NIPPGSTAYVTGWGAQEYAGHTVPELRQGQVRIISNDVCNAPHSYNGAILSGMLCAGVPQ 358
+ VTGWG G L++ ++II N +CNA ++Y+G + MLCAG
Sbjct: 297 KLSENDNVVVTGWGTLYMNGSFPVILQEDFLKIIDNKICNASYAYSGFVTDTMLCAGFMS 356
Query: 359 GGVDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQCGLPDKPGVYTRVTAYLDWIRQQTGI 418
G DACQ DSGGPL DSR +W +VGIVSWGD CG +KPGVYTRVT+Y +WI +TG+
Sbjct: 357 GEADACQNDSGGPLAYPDSRNIWHLVGIVSWGDGCGKKNKPGVYTRVTSYRNWITSKTGL 416
>gi|33695155 hepsin [Homo sapiens]
Length = 417
Score = 213 bits (541), Expect = 3e-55
Identities = 113/245 (46%), Positives = 144/245 (58%), Gaps = 12/245 (4%)
Query: 182 LSEQRILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCF--RSNSNPRDWI 239
L RI+GG + G WPWQVSLR + AH CGGSL++ W+LTAAHCF R+ R +
Sbjct: 158 LPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRV 217
Query: 240 ATSGISTTFPK-LRMRVRNILIHNNY------KSATHENDIALVRLENSVTFTKDIHSVC 292
++ P L++ V+ ++ H Y S + NDIALV L + + T+ I VC
Sbjct: 218 FAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVC 277
Query: 293 LPAATQNIPPGSTAYVTGWGAQEYAGHTVPELRQGQVRIISNDVCNAPHSYNGAILSGML 352
LPAA Q + G VTGWG +Y G L++ +V IISNDVCN Y I M
Sbjct: 278 LPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMF 337
Query: 353 CAGVPQGGVDACQGDSGGPLVQEDS---RRLWFIVGIVSWGDQCGLPDKPGVYTRVTAYL 409
CAG P+GG+DACQGDSGGP V EDS W + GIVSWG C L KPGVYT+V+ +
Sbjct: 338 CAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFR 397
Query: 410 DWIRQ 414
+WI Q
Sbjct: 398 EWIFQ 402
>gi|4504481 hepsin [Homo sapiens]
Length = 417
Score = 213 bits (541), Expect = 3e-55
Identities = 113/245 (46%), Positives = 144/245 (58%), Gaps = 12/245 (4%)
Query: 182 LSEQRILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCF--RSNSNPRDWI 239
L RI+GG + G WPWQVSLR + AH CGGSL++ W+LTAAHCF R+ R +
Sbjct: 158 LPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRV 217
Query: 240 ATSGISTTFPK-LRMRVRNILIHNNY------KSATHENDIALVRLENSVTFTKDIHSVC 292
++ P L++ V+ ++ H Y S + NDIALV L + + T+ I VC
Sbjct: 218 FAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVC 277
Query: 293 LPAATQNIPPGSTAYVTGWGAQEYAGHTVPELRQGQVRIISNDVCNAPHSYNGAILSGML 352
LPAA Q + G VTGWG +Y G L++ +V IISNDVCN Y I M
Sbjct: 278 LPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMF 337
Query: 353 CAGVPQGGVDACQGDSGGPLVQEDS---RRLWFIVGIVSWGDQCGLPDKPGVYTRVTAYL 409
CAG P+GG+DACQGDSGGP V EDS W + GIVSWG C L KPGVYT+V+ +
Sbjct: 338 CAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFR 397
Query: 410 DWIRQ 414
+WI Q
Sbjct: 398 EWIFQ 402
>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo
sapiens]
Length = 454
Score = 210 bits (535), Expect = 2e-54
Identities = 143/413 (34%), Positives = 206/413 (49%), Gaps = 35/413 (8%)
Query: 22 IVVAGVV--ILAVTIALLVYFLAFDQKSYFYRSSFQLLNVEYNSQLNSPATQ---EYRTL 76
I+V G++ ILA+ I L ++F + Y RSSF+ + + S EYR +
Sbjct: 51 IIVIGIIALILALAIGLGIHFDCSGK--YRCRSSFKCIELIARCDGVSDCKDGEDEYRCV 108
Query: 77 SGRIESLITKTFKESNLRNQFIRAHVAKLRQDGSGVRADVVMKFQFTRNNNGASMKSRIE 136
++ + + F ++ + D G A+V Q + +S R+
Sbjct: 109 RVGGQNAVLQVFTAASWKTM--------CSDDWKGHYANVACA-QLGFPSYVSSDNLRVS 159
Query: 137 SVLRQMLNNSGNLE-INPSTEITSLTDQAAANWLINECGAGPDLITLS----------EQ 185
S+ Q +++ + P ++T+L + E A ++TL
Sbjct: 160 SLEGQFREEFVSIDHLLPDDKVTALHHSV----YVREGCASGHVVTLQCTACGHRRGYSS 215
Query: 186 RILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCFRSNSNPRDWIATSGIS 245
RI+GG + WPWQ SL+ H CGGS+I +WI+TAAHC P+ W G+
Sbjct: 216 RIVGGNMSLLSQWPWQASLQFQGYHLCGGSVITPLWIITAAHCVYDLYLPKSWTIQVGLV 275
Query: 246 TTF--PKLRMRVRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSVCLPAATQNIPPG 303
+ P V I+ H+ YK NDIAL++L +TF + I VCLP + +N P G
Sbjct: 276 SLLDNPAPSHLVEKIVYHSKYKPKRLGNDIALMKLAGPLTFNEMIQPVCLPNSEENFPDG 335
Query: 304 STAYVTGWGAQEY-AGHTVPELRQGQVRIISNDVCNAPHSYNGAILSGMLCAGVPQGGVD 362
+ +GWGA E AG P L V +ISN +CN Y G I MLCAG GGVD
Sbjct: 336 KVCWTSGWGATEDGAGDASPVLNHAAVPLISNKICNHRDVYGGIISPSMLCAGYLTGGVD 395
Query: 363 ACQGDSGGPLVQEDSRRLWFIVGIVSWGDQCGLPDKPGVYTRVTAYLDWIRQQ 415
+CQGDSGGPLV ++ RRLW +VG S+G C +KPGVYTRVT++LDWI +Q
Sbjct: 396 SCQGDSGGPLVCQE-RRLWKLVGATSFGIGCAEVNKPGVYTRVTSFLDWIHEQ 447
>gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo
sapiens]
Length = 432
Score = 209 bits (533), Expect = 3e-54
Identities = 136/417 (32%), Positives = 214/417 (51%), Gaps = 47/417 (11%)
Query: 16 PYVVCFIVVAGVVILAVTIALLV---YFLAFDQKSYFYRSSFQLLNVEYNSQLNSPATQE 72
P ++ + +A ++I+ V I +++ YFL + R QL + E + L
Sbjct: 35 PIIIALLSLASIIIVVVLIKVILDKYYFLCGQPLHFIPRK--QLCDGELDCPL------- 85
Query: 73 YRTLSGRIESLITKTFKESNLRNQFIRAHVAKLRQDGSGVRA-DVVMKFQFTRNNNGASM 131
G E K+F E A +L +D S ++ D F+ + +
Sbjct: 86 -----GEDEEHCVKSFPEGP-------AVAVRLSKDRSTLQVLDSATGNWFSACFDNFT- 132
Query: 132 KSRIESVLRQMLNNSGNLEINPSTEITSLTDQAAANWLINECGAGPDLI----------- 180
++ E+ RQM S +EI P ++ + + L +GP L
Sbjct: 133 EALAETACRQM-GYSRAVEIGPDQDLDVVEITENSQELRMRNSSGPCLSGSLVSLHCLAC 191
Query: 181 --TLSEQRILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCFRSNSNPRDW 238
+L R++GG EA SWPWQVS++ + H CGGS+++ W+LTAAHCFR +++ +W
Sbjct: 192 GKSLKTPRVVGGEEASVDSWPWQVSIQYDKQHVCGGSILDPHWVLTAAHCFRKHTDVFNW 251
Query: 239 IATSGIST--TFPKLRMRVRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSVCLPAA 296
+G +FP L V I+I +NDIAL++L+ +TF+ + +CLP
Sbjct: 252 KVRAGSDKLGSFPSL--AVAKIIIIEFNPMYPKDNDIALMKLQFPLTFSGTVRPICLPFF 309
Query: 297 TQNIPPGSTAYVTGWGAQEYAGHTVPE-LRQGQVRIISNDVCNAPHSYNGAILSGMLCAG 355
+ + P + ++ GWG + G + + L Q V++I + CNA +Y G + M+CAG
Sbjct: 310 DEELTPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNADDAYQGEVTEKMMCAG 369
Query: 356 VPQGGVDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQCGLPDKPGVYTRVTAYLDWI 412
+P+GGVD CQGDSGGPL+ + + W +VGIVSWG CG P PGVYT+V+AYL+WI
Sbjct: 370 IPEGGVDTCQGDSGGPLMYQSDQ--WHVVGIVSWGYGCGGPSTPGVYTKVSAYLNWI 424
>gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo
sapiens]
Length = 437
Score = 209 bits (532), Expect = 4e-54
Identities = 100/235 (42%), Positives = 148/235 (62%), Gaps = 7/235 (2%)
Query: 181 TLSEQRILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCFRSNSNPRDWIA 240
+L R++GG EA SWPWQVS++ + H CGGS+++ W+LTAAHCFR +++ +W
Sbjct: 199 SLKTPRVVGGEEASVDSWPWQVSIQYDKQHVCGGSILDPHWVLTAAHCFRKHTDVFNWKV 258
Query: 241 TSGIST--TFPKLRMRVRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSVCLPAATQ 298
+G +FP L V I+I +NDIAL++L+ +TF+ + +CLP +
Sbjct: 259 RAGSDKLGSFPSL--AVAKIIIIEFNPMYPKDNDIALMKLQFPLTFSGTVRPICLPFFDE 316
Query: 299 NIPPGSTAYVTGWGAQEYAGHTVPE-LRQGQVRIISNDVCNAPHSYNGAILSGMLCAGVP 357
+ P + ++ GWG + G + + L Q V++I + CNA +Y G + M+CAG+P
Sbjct: 317 ELTPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNADDAYQGEVTEKMMCAGIP 376
Query: 358 QGGVDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQCGLPDKPGVYTRVTAYLDWI 412
+GGVD CQGDSGGPL+ + + W +VGIVSWG CG P PGVYT+V+AYL+WI
Sbjct: 377 EGGVDTCQGDSGGPLMYQSDQ--WHVVGIVSWGYGCGGPSTPGVYTKVSAYLNWI 429
>gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo
sapiens]
Length = 529
Score = 204 bits (519), Expect = 1e-52
Identities = 103/244 (42%), Positives = 139/244 (56%), Gaps = 5/244 (2%)
Query: 176 GPDLITLSEQRILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCFRSN-SN 234
G +L + + RI+GG A G+WPWQVSL + N H CGGS+I WI+TAAHC +N
Sbjct: 282 GVNLNSSRQSRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEKPLNN 341
Query: 235 PRDWIATSGI---STTFPKLRMRVRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSV 291
P W A +GI S F +V ++ H NY S T NDIAL++L+ +TF + V
Sbjct: 342 PWHWTAFAGILRQSFMFYGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPV 401
Query: 292 CLPAATQNIPPGSTAYVTGWGAQEYAGHTVPELRQGQVRIISNDVCNAPHSYNGAILSGM 351
CLP + P +++GWGA E G T L +V +I CN+ + Y+ I M
Sbjct: 402 CLPNPGMMLQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLITPAM 461
Query: 352 LCAGVPQGGVDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQCGLPDKPGVYTRVTAYLDW 411
+CAG QG VD+CQGDSGGPLV +W+++G SWG C +PGVY V + DW
Sbjct: 462 ICAGFLQGNVDSCQGDSGGPLV-TSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDW 520
Query: 412 IRQQ 415
I +Q
Sbjct: 521 IYRQ 524
>gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo
sapiens]
Length = 492
Score = 204 bits (519), Expect = 1e-52
Identities = 103/244 (42%), Positives = 139/244 (56%), Gaps = 5/244 (2%)
Query: 176 GPDLITLSEQRILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCFRSN-SN 234
G +L + + RI+GG A G+WPWQVSL + N H CGGS+I WI+TAAHC +N
Sbjct: 245 GVNLNSSRQSRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEKPLNN 304
Query: 235 PRDWIATSGI---STTFPKLRMRVRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSV 291
P W A +GI S F +V ++ H NY S T NDIAL++L+ +TF + V
Sbjct: 305 PWHWTAFAGILRQSFMFYGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPV 364
Query: 292 CLPAATQNIPPGSTAYVTGWGAQEYAGHTVPELRQGQVRIISNDVCNAPHSYNGAILSGM 351
CLP + P +++GWGA E G T L +V +I CN+ + Y+ I M
Sbjct: 365 CLPNPGMMLQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLITPAM 424
Query: 352 LCAGVPQGGVDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQCGLPDKPGVYTRVTAYLDW 411
+CAG QG VD+CQGDSGGPLV +W+++G SWG C +PGVY V + DW
Sbjct: 425 ICAGFLQGNVDSCQGDSGGPLV-TSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDW 483
Query: 412 IRQQ 415
I +Q
Sbjct: 484 IYRQ 487
>gi|205360905 testis-specific serine protease 1 [Homo sapiens]
Length = 318
Score = 197 bits (500), Expect = 2e-50
Identities = 103/242 (42%), Positives = 138/242 (57%), Gaps = 16/242 (6%)
Query: 187 ILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCFRSNSNPRDWIATSGIST 246
+ GG E+ G WPWQ SLRL H CGGSL++ W+L+AAHCF+ + P +W G T
Sbjct: 55 VAGGVESARGRWPWQASLRLRRRHRCGGSLLSRRWVLSAAHCFQKHYYPSEWTVQLGELT 114
Query: 247 TFP--------KLRMRVRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSVCLPAATQ 298
+ P R +V++I++ N NDIAL+RL +SVT+ I +C+ ++T
Sbjct: 115 SRPTPWNLRAYSSRYKVQDIIV-NPDALGVLRNDIALLRLASSVTYNAYIQPICIESSTF 173
Query: 299 NIPPGSTAYVTGWGAQEYAGHTVP---ELRQGQVRIISNDVCN---APHSYNGAILSGML 352
N +VTGWG +G +P LR+ QV I++N CN S I M
Sbjct: 174 NFVHRPDCWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRCNYLFEQPSSRSMIWDSMF 233
Query: 353 CAGVPQGGVDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQCGLPDKPGVYTRVTAYLDWI 412
CAG G VD C+GDSGGPLV D LW+ VGIVSWG CG P++PGVYT ++ Y WI
Sbjct: 234 CAGAEDGSVDTCKGDSGGPLVC-DKDGLWYQVGIVSWGMDCGQPNRPGVYTNISVYFHWI 292
Query: 413 RQ 414
R+
Sbjct: 293 RR 294
>gi|170932492 transmembrane protease, serine 5 [Homo sapiens]
Length = 457
Score = 194 bits (494), Expect = 1e-49
Identities = 104/249 (41%), Positives = 139/249 (55%), Gaps = 14/249 (5%)
Query: 171 NECGAGPDLITLSEQRILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCFR 230
+ECGA P RI+GG G WPWQ S+ L H CGGS++ W++TAAHC
Sbjct: 207 SECGARP-----LASRIVGGQSVAPGRWPWQASVALGFRHTCGGSVLAPRWVVTAAHCMH 261
Query: 231 SNSNPR--DWIATSGI---STTFPKLRMRVRNILIHNNYKSATHENDIALVRLENSVTFT 285
S R W +G+ S P V I+ H Y + H+ D+AL+RL+ ++ F+
Sbjct: 262 SFRLARLSSWRVHAGLVSHSAVRPHQGALVERIIPHPLYSAQNHDYDVALLRLQTALNFS 321
Query: 286 KDIHSVCLPAATQNIPPGSTAYVTGWGAQEYAGHTVPE--LRQGQVRIISNDVCNAPHSY 343
+ +VCLPA Q+ P GS +V+GWG + HT L+ V + S +CN+ Y
Sbjct: 322 DTVGAVCLPAKEQHFPKGSRCWVSGWG-HTHPSHTYSSDMLQDTVVPLFSTQLCNSSCVY 380
Query: 344 NGAILSGMLCAGVPQGGVDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQCGLPDKPGVYT 403
+GA+ MLCAG G DACQGDSGGPLV D W +VG+VSWG C P+ PGVY
Sbjct: 381 SGALTPRMLCAGYLDGRADACQGDSGGPLVCPDG-DTWRLVGVVSWGRGCAEPNHPGVYA 439
Query: 404 RVTAYLDWI 412
+V +LDWI
Sbjct: 440 KVAEFLDWI 448
>gi|11415040 matriptase [Homo sapiens]
Length = 855
Score = 194 bits (492), Expect = 2e-49
Identities = 103/285 (36%), Positives = 155/285 (54%), Gaps = 21/285 (7%)
Query: 145 NSGNLEINPSTEITSLTDQAAANWLINECGAGPDLITLSEQRILGGTEAEEGSWPWQVSL 204
+ GN E + + + +D+ +C G T + R++GGT+A+EG WPWQVSL
Sbjct: 581 SKGNPECDGKEDCSDGSDE-------KDCDCGLRSFT-RQARVVGGTDADEGEWPWQVSL 632
Query: 205 R-LNNAHHCGGSLINNMWILTAAHCFRSN-----SNPRDWIATSGISTTFPKL-----RM 253
L H CG SLI+ W+++AAHC+ + S+P W A G+ +
Sbjct: 633 HALGQGHICGASLISPNWLVSAAHCYIDDRGFRYSDPTQWTAFLGLHDQSQRSAPGVQER 692
Query: 254 RVRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSVCLPAATQNIPPGSTAYVTGWGA 313
R++ I+ H + T + DIAL+ LE ++ + +CLP A+ P G +VTGWG
Sbjct: 693 RLKRIISHPFFNDFTFDYDIALLELEKPAEYSSMVRPICLPDASHVFPAGKAIWVTGWGH 752
Query: 314 QEYAGHTVPELRQGQVRIISNDVCNAPHSYNGAILSGMLCAGVPQGGVDACQGDSGGPLV 373
+Y G L++G++R+I+ C + I M+C G GGVD+CQGDSGGPL
Sbjct: 753 TQYGGTGALILQKGEIRVINQTTCE--NLLPQQITPRMMCVGFLSGGVDSCQGDSGGPLS 810
Query: 374 QEDSRRLWFIVGIVSWGDQCGLPDKPGVYTRVTAYLDWIRQQTGI 418
++ F G+VSWGD C +KPGVYTR+ + DWI++ TG+
Sbjct: 811 SVEADGRIFQAGVVSWGDGCAQRNKPGVYTRLPLFRDWIKENTGV 855
>gi|33667063 transmembrane protease, serine 9 [Homo sapiens]
Length = 1059
Score = 194 bits (492), Expect = 2e-49
Identities = 135/424 (31%), Positives = 208/424 (49%), Gaps = 41/424 (9%)
Query: 20 CFIVVAGVVILAVTIALLVYFLAF-DQKSYFYRSSFQLLNVEYNSQLNSPATQEYRTLSG 78
C GVV ++ + L LAF + + + +L + + S L + +RTL+
Sbjct: 26 CRAASIGVVATSLVVLTLGVLLAFLSTQGFHVDHTAELRGIRWTSSLRRETSDYHRTLTP 85
Query: 79 RIESLITKTFK---------ESNLRNQFIRAHVAKLRQDGSGVRA-DVVMKFQFTRNNNG 128
+E+L+ + E L + IRA +LR+ G + A ++ + T + G
Sbjct: 86 TLEALLHFLLRPLQTLSLGLEEELLQRGIRA---RLREHGISLAAYGTIVSAELTGRHKG 142
Query: 129 ASMKSRIESVLRQMLNNS---GNLE----INPSTE----ITSLTDQAAANWLINECGAGP 177
+ +S + NS GN + +NP + + +D+A ECG P
Sbjct: 143 PLAERDFKS--GRCPGNSFSCGNSQCVTKVNPECDDQEDCSDGSDEAHC-----ECGLQP 195
Query: 178 DLITLSEQRILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCFRSNSNPRD 237
RI+GG EA G +PWQ SLR N H CG ++IN W+++AAHCF +P
Sbjct: 196 AWRMAG--RIVGGMEASPGEFPWQASLRENKEHFCGAAIINARWLVSAAHCFNEFQDPTK 253
Query: 238 WIATSGIS----TTFPKLRMRVRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSVCL 293
W+A G + + +R +V I+ H Y + T + D+A++ L + + F + I VCL
Sbjct: 254 WVAYVGATYLSGSEASTVRAQVVQIVKHPLYNADTADFDVAVLELTSPLPFGRHIQPVCL 313
Query: 294 PAATQNIPPGSTAYVTGWGAQEYAGHTVPE-LRQGQVRIISNDVCNAPHSYNGAILSGML 352
PAAT PP ++GWG + PE L++ V ++ +C + Y ++ M+
Sbjct: 314 PAATHIFPPSKKCLISGWGYLKEDFLVKPEVLQKATVELLDQALCAS--LYGHSLTDRMV 371
Query: 353 CAGVPQGGVDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQCGLPDKPGVYTRVTAYLDWI 412
CAG G VD+CQGDSGGPLV E+ +F+ GIVSWG C +PGVY RVT DWI
Sbjct: 372 CAGYLDGKVDSCQGDSGGPLVCEEPSGRFFLAGIVSWGIGCAEARRPGVYARVTRLRDWI 431
Query: 413 RQQT 416
+ T
Sbjct: 432 LEAT 435
Score = 188 bits (478), Expect = 7e-48
Identities = 102/256 (39%), Positives = 136/256 (53%), Gaps = 11/256 (4%)
Query: 163 QAAANWLINECGAGPDLITLSEQRILGGTEAEEGSWPWQVSLRLNNAHH-CGGSLINNMW 221
+A + + +CG P +T RI+GG+ A G WPWQVSL L H CG L+ W
Sbjct: 807 EATTHTQLPDCGLAPAALT----RIVGGSAAGRGEWPWQVSLWLRRREHRCGAVLVAERW 862
Query: 222 ILTAAHCFRSNSNPRDWIATSG---ISTTFPKLRMRVRNILIHNNYKSATHENDIALVRL 278
+L+AAHCF +P+ W A G +S +L RV I H Y T + D+AL+ L
Sbjct: 863 LLSAAHCFDVYGDPKQWAAFLGTPFLSGAEGQLE-RVARIYKHPFYNLYTLDYDVALLEL 921
Query: 279 ENSVTFTKDIHSVCLPAATQNIPPGSTAYVTGWGAQEYAGHTVPELRQGQVRIISNDVCN 338
V ++ + +CLP P G+ +TGWG+ G +L++ VR++S C
Sbjct: 922 AGPVRRSRLVRPICLPEPAPRPPDGTRCVITGWGSVREGGSMARQLQKAAVRLLSEQTCR 981
Query: 339 APHSYNGAILSGMLCAGVPQGGVDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQCGLPDK 398
Y I S MLCAG PQGGVD+C GD+GGPL + W + G+ SWG CG P
Sbjct: 982 --RFYPVQISSRMLCAGFPQGGVDSCSGDAGGPLACREPSGRWVLTGVTSWGYGCGRPHF 1039
Query: 399 PGVYTRVTAYLDWIRQ 414
PGVYTRV A WI Q
Sbjct: 1040 PGVYTRVAAVRGWIGQ 1055
Score = 175 bits (444), Expect = 6e-44
Identities = 93/247 (37%), Positives = 137/247 (55%), Gaps = 8/247 (3%)
Query: 170 INECGAGPDLITLSEQRILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCF 229
+ ECGA P + R++GG A G PWQVSL+ + H CG +++ + W+L+AAHCF
Sbjct: 489 LQECGARPAME--KPTRVVGGFGAASGEVPWQVSLKEGSRHFCGATVVGDRWLLSAAHCF 546
Query: 230 RSNS--NPRDWIATSGI-STTFPKLRMRVRNILIHNNYKSATHENDIALVRLENSVTFTK 286
R + T+ + +++ +R +++H Y + D+A++ L + + F K
Sbjct: 547 NHTKVEQVRAHLGTASLLGLGGSPVKIGLRRVVLHPLYNPGILDFDLAVLELASPLAFNK 606
Query: 287 DIHSVCLPAATQNIPPGSTAYVTGWGAQEYAGHTVPELRQ-GQVRIISNDVCNAPHSYNG 345
I VCLP A Q P G ++GWG + T PEL Q V II C+ YN
Sbjct: 607 YIQPVCLPLAIQKFPVGRKCMISGWGNTQEGNATKPELLQKASVGIIDQKTCSV--LYNF 664
Query: 346 AILSGMLCAGVPQGGVDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQCGLPDKPGVYTRV 405
++ M+CAG +G VD+CQGDSGGPL E++ ++++ GIVSWG C KPGVYTR+
Sbjct: 665 SLTDRMICAGFLEGKVDSCQGDSGGPLACEEAPGVFYLAGIVSWGIGCAQVKKPGVYTRI 724
Query: 406 TAYLDWI 412
T WI
Sbjct: 725 TRLKGWI 731
>gi|223942069 enterokinase precursor [Homo sapiens]
Length = 1019
Score = 191 bits (484), Expect = 1e-48
Identities = 118/354 (33%), Positives = 180/354 (50%), Gaps = 54/354 (15%)
Query: 107 QDGSGVRADVVMKFQFTRNNNGASMKSRIESVLRQMLNNSGNLEINPSTEITSLTDQAAA 166
+DGS AD V F T NNNG ++ RI+S+ + +I S ++ L +
Sbjct: 669 EDGSD-EADCVRFFNGTTNNNGL-VRFRIQSIWHTACAENWTTQI--SNDVCQLLGLGSG 724
Query: 167 NWL-------------INECGAGPDLITLSEQ---------------------------R 186
N +N G ++T S+Q +
Sbjct: 725 NSSKPIFSTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPK 784
Query: 187 ILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHC-FRSNSNPRDWIATSGI- 244
I+GG+ A+EG+WPW V L CG SL+++ W+++AAHC + N P W A G+
Sbjct: 785 IVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLH 844
Query: 245 ---STTFPKLRMR-VRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSVCLPAATQNI 300
+ T P+ R + I+I+ +Y +NDIA++ LE V +T I +CLP Q
Sbjct: 845 MKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVF 904
Query: 301 PPGSTAYVTGWGAQEYAGHTVPELRQGQVRIISNDVCNAP-HSYNGAILSGMLCAGVPQG 359
PPG + GWG Y G T L++ V ++SN+ C YN I M+CAG +G
Sbjct: 905 PPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYN--ITENMICAGYEEG 962
Query: 360 GVDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQCGLPDKPGVYTRVTAYLDWIR 413
G+D+CQGDSGGPL+ +++ R WF+ G+ S+G +C LP++PGVY RV+ + +WI+
Sbjct: 963 GIDSCQGDSGGPLMCQENNR-WFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQ 1015
Score = 35.0 bits (79), Expect = 0.13
Identities = 23/113 (20%), Positives = 57/113 (50%), Gaps = 10/113 (8%)
Query: 7 VTSTSRFLNPYVVCFIVVAGVVILAVTIALLVYFLAFDQ--------KSYFYRSSFQLLN 58
++S L+ Y + F + ++++ + V L + +S+ R++F++ +
Sbjct: 7 ISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITS 66
Query: 59 -VEYNSQLNSPATQEYRTLSGRIESLITKTFKESNLRNQFIRAHVAKLRQDGS 110
V YN L + +++ L+ ++ +I + F SNL+N++ + V + ++GS
Sbjct: 67 GVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQF-ENGS 118
>gi|23957702 transmembrane protease, serine 6 [Homo sapiens]
Length = 811
Score = 191 bits (484), Expect = 1e-48
Identities = 93/235 (39%), Positives = 139/235 (59%), Gaps = 8/235 (3%)
Query: 186 RILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCFRSNSNPRDWIATSGIS 245
RI+GG + EG WPWQ SL++ H CGG+LI + W++TAAHCF+ +S + T +
Sbjct: 576 RIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCFQEDSMASTVLWTVFLG 635
Query: 246 TTFPKLR------MRVRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSVCLPAATQN 299
+ R +V +L+H ++ +H+ D+AL++L++ V + + VCLPA +
Sbjct: 636 KVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHPVVRSAAVRPVCLPARSHF 695
Query: 300 IPPGSTAYVTGWGAQEYAGHTVPELRQGQVRIISNDVCNAPHSYNGAILSGMLCAGVPQG 359
PG ++TGWGA G L++ V++I D+C+ + Y + MLCAG +G
Sbjct: 696 FEPGLHCWITGWGALREGGPISNALQKVDVQLIPQDLCSEVYRYQ--VTPRMLCAGYRKG 753
Query: 360 GVDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQCGLPDKPGVYTRVTAYLDWIRQ 414
DACQGDSGGPLV + WF+ G+VSWG CG P+ GVYTR+T + WI+Q
Sbjct: 754 KKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVYTRITGVISWIQQ 808
>gi|148613878 acrosin precursor [Homo sapiens]
Length = 421
Score = 189 bits (480), Expect = 4e-48
Identities = 101/249 (40%), Positives = 137/249 (55%), Gaps = 17/249 (6%)
Query: 186 RILGGTEAEEGSWPWQVSLRL-----NNAHHCGGSLINNMWILTAAHCFRSNSNPRDWIA 240
RI+GG A+ G+WPW VSL++ + H CGGSL+N+ W+LTAAHCF +N DW
Sbjct: 42 RIVGGKAAQHGAWPWMVSLQIFTYNSHRYHTCGGSLLNSRWVLTAAHCFVGKNNVHDWRL 101
Query: 241 TSGIS---------TTFPKLRMRVRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSV 291
G P V I+IH Y SAT NDIALV + ++ + I
Sbjct: 102 VFGAKEITYGNNKPVKAPLQERYVEKIIIHEKYNSATEGNDIALVEITPPISCGRFIGPG 161
Query: 292 CLPAATQNIPPGS-TAYVTGWG-AQEYAGHTVPELRQGQVRIISNDVCNAPHSYNGAILS 349
CLP +P GS + +V GWG +E A L + +V +I D+CN+ YNG +
Sbjct: 162 CLPHFKAGLPRGSQSCWVAGWGYIEEKAPRPSSILMEARVDLIDLDLCNSTQWYNGRVQP 221
Query: 350 GMLCAGVPQGGVDACQGDSGGPLVQEDSRR-LWFIVGIVSWGDQCGLPDKPGVYTRVTAY 408
+CAG P G +D CQGDSGGPL+ +DS+ + +VGI SWG C +PG+YT Y
Sbjct: 222 TNVCAGYPVGKIDTCQGDSGGPLMCKDSKESAYVVVGITSWGVGCARAKRPGIYTATWPY 281
Query: 409 LDWIRQQTG 417
L+WI + G
Sbjct: 282 LNWIASKIG 290
>gi|21614531 testisin isoform 2 [Homo sapiens]
Length = 312
Score = 188 bits (478), Expect = 7e-48
Identities = 106/254 (41%), Positives = 149/254 (58%), Gaps = 16/254 (6%)
Query: 175 AGPDLITLSEQRILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCFRSN-S 233
+GP + RI+GG +AE G WPWQ SLRL ++H CG SL+++ W LTAAHCF ++ S
Sbjct: 30 SGPCGRRVITSRIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETDLS 89
Query: 234 NPRDWIATSGISTTFPKL--------RMRVRNILIHNNYKSATHENDIALVRLENSVTFT 285
+P W+ G T+ P R V NI + Y DIALV+L VT+T
Sbjct: 90 DPSGWMVQFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRY-LGNSPYDIALVKLSAPVTYT 148
Query: 286 KDIHSVCLPAATQNIPPGSTAYVTGWG--AQEYAGHTVPELRQGQVRIISNDVCN---AP 340
K I +CL A+T + +VTGWG ++ A + L++ QV II+N +CN
Sbjct: 149 KHIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLK 208
Query: 341 HSYNGAILSGMLCAGVPQGGVDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQCGLPDKPG 400
+S+ I M+CAG QGG DAC GDSGGPL + LW+ +G+VSWG CG P++PG
Sbjct: 209 YSFRKDIFGDMVCAGNAQGGKDACFGDSGGPLAC-NKNGLWYQIGVVSWGVGCGRPNRPG 267
Query: 401 VYTRVTAYLDWIRQ 414
VYT ++ + +WI++
Sbjct: 268 VYTNISHHFEWIQK 281
>gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
Length = 638
Score = 187 bits (475), Expect = 2e-47
Identities = 98/263 (37%), Positives = 151/263 (57%), Gaps = 11/263 (4%)
Query: 163 QAAANWLINECGAGPDLI--TLSEQRILGGTEAEEGSWPWQVSLRLN---NAHHCGGSLI 217
Q ++ + + C G + + T + RI+GGT + G WPWQVSL++ H CGGSLI
Sbjct: 365 QGSSGYSLRLCNTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLI 424
Query: 218 NNMWILTAAHCFRSNSNPRDWIATSGI----STTFPKLRMRVRNILIHNNYKSATHENDI 273
+ W+LTAAHCF W SGI T +++ I+IH NYK + +DI
Sbjct: 425 GHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDI 484
Query: 274 ALVRLENSVTFTKDIHSVCLPAATQNIPPGSTAYVTGWGAQEYAGHTVPELRQGQVRIIS 333
AL++L+ + +T+ +CLP+ + +VTGWG + G L++ + +++
Sbjct: 485 ALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVT 544
Query: 334 NDVCNAPHSYNGAILSGMLCAGVPQGGVDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQC 393
N+ C + + I M+CAG +GG DAC+GDSGGPLV + + +W +VGI SWG+ C
Sbjct: 545 NEECQKRYQ-DYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHN-GMWRLVGITSWGEGC 602
Query: 394 GLPDKPGVYTRVTAYLDWIRQQT 416
++PGVYT+V Y+DWI ++T
Sbjct: 603 ARREQPGVYTKVAEYMDWILEKT 625
>gi|5803197 testisin isoform 1 [Homo sapiens]
Length = 314
Score = 186 bits (473), Expect = 3e-47
Identities = 106/256 (41%), Positives = 148/256 (57%), Gaps = 18/256 (7%)
Query: 175 AGPDLITLSEQRILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCFRSN-- 232
+GP + RI+GG +AE G WPWQ SLRL ++H CG SL+++ W LTAAHCF +
Sbjct: 30 SGPCGRRVITSRIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETYSD 89
Query: 233 -SNPRDWIATSGISTTFPKL--------RMRVRNILIHNNYKSATHENDIALVRLENSVT 283
S+P W+ G T+ P R V NI + Y DIALV+L VT
Sbjct: 90 LSDPSGWMVQFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRY-LGNSPYDIALVKLSAPVT 148
Query: 284 FTKDIHSVCLPAATQNIPPGSTAYVTGWG--AQEYAGHTVPELRQGQVRIISNDVCN--- 338
+TK I +CL A+T + +VTGWG ++ A + L++ QV II+N +CN
Sbjct: 149 YTKHIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLF 208
Query: 339 APHSYNGAILSGMLCAGVPQGGVDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQCGLPDK 398
+S+ I M+CAG QGG DAC GDSGGPL + LW+ +G+VSWG CG P++
Sbjct: 209 LKYSFRKDIFGDMVCAGNAQGGKDACFGDSGGPLAC-NKNGLWYQIGVVSWGVGCGRPNR 267
Query: 399 PGVYTRVTAYLDWIRQ 414
PGVYT ++ + +WI++
Sbjct: 268 PGVYTNISHHFEWIQK 283
>gi|4506153 prostasin preproprotein [Homo sapiens]
Length = 343
Score = 186 bits (471), Expect = 4e-47
Identities = 99/255 (38%), Positives = 141/255 (55%), Gaps = 19/255 (7%)
Query: 173 CGAGPDLITLSEQRILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCFRSN 232
CG P + RI GG+ A G WPWQVS+ H CGGSL++ W+L+AAHCF S
Sbjct: 37 CGVAP------QARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSE 90
Query: 233 SNPRDWIATSGI----STTFPKLRMRVRNILIHNNYKSATHENDIALVRLENSVTFTKDI 288
+ + G S + +++I+ H +Y + DIAL++L +TF++ I
Sbjct: 91 HHKEAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYI 150
Query: 289 HSVCLPAATQNIPPGSTAYVTGWG--AQEYAGHTVPELRQGQVRIISNDVCNAPHSYNGA 346
+CLPAA + P G VTGWG A + T L+Q +V +IS + CN ++ +
Sbjct: 151 RPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAK 210
Query: 347 ------ILSGMLCAGVPQGGVDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQCGLPDKPG 400
+ M+CAG +GG DACQGDSGGPL LW++ GIVSWGD CG ++PG
Sbjct: 211 PEEPHFVQEDMVCAGYVEGGKDACQGDSGGPL-SCPVEGLWYLTGIVSWGDACGARNRPG 269
Query: 401 VYTRVTAYLDWIRQQ 415
VYT ++Y WI+ +
Sbjct: 270 VYTLASSYASWIQSK 284
>gi|116256363 transmembrane protease, serine 13 [Homo sapiens]
Length = 567
Score = 185 bits (470), Expect = 6e-47
Identities = 99/232 (42%), Positives = 131/232 (56%), Gaps = 7/232 (3%)
Query: 186 RILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCFRSNSNP--RDWIATSG 243
RI+GG A + WPWQVSL H CGG+LI+ W+LTAAHCF W +G
Sbjct: 325 RIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEGWKVYAG 384
Query: 244 IST--TFPKLRMRVRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSVCLPAATQNIP 301
S P+ + I+I++NY + DIAL+RL +T + IH CLP Q
Sbjct: 385 TSNLHQLPE-AASIAEIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPACLPMHGQTFS 443
Query: 302 PGSTAYVTGWG-AQEYAGHTVPELRQGQVRIISNDVCNAPHSYNGAILSGMLCAGVPQGG 360
T ++TG+G +E T P LR+ QV +I CN Y+ + M+CAG +GG
Sbjct: 444 LNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAGDLRGG 503
Query: 361 VDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQCGLPDKPGVYTRVTAYLDWI 412
D+CQGDSGGPLV E + R W++ G+ SWG CG +KPGVYT+VT L WI
Sbjct: 504 RDSCQGDSGGPLVCEQNNR-WYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWI 554
>gi|4503627 coagulation factor XI precursor [Homo sapiens]
Length = 625
Score = 184 bits (467), Expect = 1e-46
Identities = 100/263 (38%), Positives = 147/263 (55%), Gaps = 19/263 (7%)
Query: 166 ANWLINECGAGPDLITLSEQRILGGTEAEEGSWPWQVSLRLNNA---HHCGGSLINNMWI 222
+ + + C + T + RI+GGT + G WPWQV+L + H CGGS+I N WI
Sbjct: 367 SGYTLRLCKMDNECTTKIKPRIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWI 426
Query: 223 LTAAHCFRSNSNPRDWIATSGI--------STTFPKLRMRVRNILIHNNYKSATHENDIA 274
LTAAHCF +P+ SGI T+F V+ I+IH+ YK A DIA
Sbjct: 427 LTAAHCFYGVESPKILRVYSGILNQSEIKEDTSF----FGVQEIIIHDQYKMAESGYDIA 482
Query: 275 LVRLENSVTFTKDIHSVCLPAATQNIPPGSTAYVTGWGAQEYAGHTVPELRQGQVRIISN 334
L++LE +V +T +CLP+ + +VTGWG ++ L++ ++ +++N
Sbjct: 483 LLKLETTVNYTDSQRPICLPSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTN 542
Query: 335 DVCNAPHSYNG-AILSGMLCAGVPQGGVDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQC 393
+ C Y G I M+CAG +GG DAC+GDSGGPL + + +W +VGI SWG+ C
Sbjct: 543 EECQ--KRYRGHKITHKMICAGYREGGKDACKGDSGGPLSCKHN-EVWHLVGITSWGEGC 599
Query: 394 GLPDKPGVYTRVTAYLDWIRQQT 416
++PGVYT V Y+DWI ++T
Sbjct: 600 AQRERPGVYTNVVEYVDWILEKT 622
>gi|32698940 transmembrane protease, serine 12 [Homo sapiens]
Length = 348
Score = 184 bits (467), Expect = 1e-46
Identities = 103/290 (35%), Positives = 154/290 (53%), Gaps = 21/290 (7%)
Query: 146 SGNLEINPSTEITSLTDQAAA-----------NWLINECGAGPDLITLSEQRILGGTEAE 194
SG + PS E + + QA A +CG P L RI+GGTEA+
Sbjct: 26 SGRHRLGPSPEPAASSQQAEAVRKRLRRRREGGAHAKDCGTAPLKDVLQGSRIIGGTEAQ 85
Query: 195 EGSWPWQVSLRLNNA----HHCGGSLINNMWILTAAHCFRSNSNPRDW---IATSGISTT 247
G+WPW VSL++ H CGG+L+ W+LTAAHC + S+P W I T+ I
Sbjct: 86 AGAWPWVVSLQIKYGRVLVHVCGGTLVRERWVLTAAHCTKDASDPLMWTAVIGTNNIHGR 145
Query: 248 FPKLR-MRVRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSVCLPAATQNIPPGST- 305
+P + ++++ I+IH N+ ++ NDIAL L+ +V + I +CLP I G+T
Sbjct: 146 YPHTKKIKIKAIIIHPNFILESYVNDIALFHLKKAVRYNDYIQPICLPFDVFQILDGNTK 205
Query: 306 AYVTGWGAQEYAGHTVPELRQGQVRIISNDVCNAPHSYNGAILSGMLCAGVPQGGVDACQ 365
+++GWG + G+ L+ +V IS ++CN+ SY G I + CAG G D C+
Sbjct: 206 CFISGWGRTKEEGNATNILQDAEVHYISREMCNSERSYGGIIPNTSFCAGDEDGAFDTCR 265
Query: 366 GDSGGPLV-QEDSRRLWFIVGIVSWGDQCGLPDKPGVYTRVTAYLDWIRQ 414
GDSGGPL+ + +F++GI S+G CG PGVY + Y W+ +
Sbjct: 266 GDSGGPLMCYLPEYKRFFVMGITSYGHGCGRRGFPGVYIGPSFYQKWLTE 315
>gi|117956391 protease, serine, 33 [Homo sapiens]
Length = 280
Score = 182 bits (463), Expect = 4e-46
Identities = 100/242 (41%), Positives = 136/242 (56%), Gaps = 16/242 (6%)
Query: 186 RILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCFRSNSNPRDWIATSG-- 243
RI+GG + +G WPWQ S++ AH CGGSLI W+LTAAHCF + P ++ G
Sbjct: 36 RIVGGRDGRDGEWPWQASIQHRGAHVCGGSLIAPQWVLTAAHCFPRRALPAEYRVRLGAL 95
Query: 244 -ISTTFPK-LRMRVRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSVCLPAATQNIP 301
+ +T P+ L + VR +L+ +Y D+AL++L V + + VCLP P
Sbjct: 96 RLGSTSPRTLSVPVRRVLLPPDYSEDGARGDLALLQLRRPVPLSARVQPVCLPVPGARPP 155
Query: 302 PGSTAYVTGWGAQEYAGHTVPELR--QG-QVRIISNDVCNAPHSYNG-------AILSGM 351
PG+ VTGWG+ G +PE R QG +V ++ + C+ + +L G
Sbjct: 156 PGTPCRVTGWGSLR-PGVPLPEWRPLQGVRVPLLDSRTCDGLYHVGADVPQAERIVLPGS 214
Query: 352 LCAGVPQGGVDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQCGLPDKPGVYTRVTAYLDW 411
LCAG PQG DACQGDSGGPL S W +VG+VSWG C LP++PGVYT V Y W
Sbjct: 215 LCAGYPQGHKDACQGDSGGPLTCLQSGS-WVLVGVVSWGKGCALPNRPGVYTSVATYSPW 273
Query: 412 IR 413
I+
Sbjct: 274 IQ 275
>gi|110815798 ovochymase 1 [Homo sapiens]
Length = 1134
Score = 182 bits (461), Expect = 6e-46
Identities = 94/251 (37%), Positives = 141/251 (56%), Gaps = 9/251 (3%)
Query: 173 CGAGPDLITLSEQRILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCFRSN 232
CG P +RI GG EA WPWQV LR + CGG++IN +WILTAAHC +
Sbjct: 561 CGIPPFSPQWLSRRIAGGEEACPHCWPWQVGLRFLGDYQCGGAIINPVWILTAAHCVQLK 620
Query: 233 SNPRDWIATSG-----ISTTFPKLRMRVRNILIHNNYKSATHENDIALVRLENSVTFTKD 287
+NP W +G + + ++R R ++I++H ++ + ++++DIAL++L + + +
Sbjct: 621 NNPLSWTIIAGDHDRNLKESTEQVR-RAKHIIVHEDFNTLSYDSDIALIQLSSPLEYNSV 679
Query: 288 IHSVCLPAATQNIPPGSTAYVTGWGAQEYAGHTVPELRQGQVRIISNDVCNAPH--SYNG 345
+ VCLP + + + VTGWG+ G L+Q QV ++ +VC + ++ G
Sbjct: 680 VRPVCLPHSAEPLFSSEICAVTGWGSISADGGLASRLQQIQVHVLEREVCEHTYYSAHPG 739
Query: 346 AILSGMLCAG-VPQGGVDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQCGLPDKPGVYTR 404
I M+CAG G D CQGDSGGPLV + + GIVSWG C P KPGV+ R
Sbjct: 740 GITEKMICAGFAASGEKDFCQGDSGGPLVCRHENGPFVLYGIVSWGAGCVQPWKPGVFAR 799
Query: 405 VTAYLDWIRQQ 415
V +LDWI+ +
Sbjct: 800 VMIFLDWIQSK 810
Score = 130 bits (327), Expect = 2e-30
Identities = 83/235 (35%), Positives = 118/235 (50%), Gaps = 19/235 (8%)
Query: 199 PWQVSLRLNNAHHCGGSLINNMWILTAAHCFRSNSNP--RDWIATSGISTTFPKLRMR-- 254
PWQVSL+ + H CGGSLI ++TAAHC S S ++ TSG + F K +
Sbjct: 59 PWQVSLKSDEHHFCGGSLIQEDRVVTAAHCLDSLSEKQLKNITVTSGEYSLFQKDKQEQN 118
Query: 255 --VRNILIHNNYKSATHEN-DIALVRLENSVTFTKDIHSVCLPAATQNIPPGSTAYVTGW 311
V I+ H Y S + + DIAL+ L++ V F + +CLP + + PG +GW
Sbjct: 119 IPVSKIITHPEYNSREYMSPDIALLYLKHKVKFGNAVQPICLPDSDDKVEPGILCLSSGW 178
Query: 312 GAQEYAGHTVPELRQGQVRIISNDVCNAP-HSYNGAILSG-MLCAGVPQGGVDACQGDSG 369
G L++ ++ I+ + CN S N L MLCAG P G+DACQGDSG
Sbjct: 179 GKISKTSEYSNVLQEMELPIMDDRACNTVLKSMNLPPLGRTMLCAGFPDWGMDACQGDSG 238
Query: 370 GPLVQEDSRRLWFIVGIVSWGDQCGLPDKP----------GVYTRVTAYLDWIRQ 414
GPLV +W + GI SW C P G++++V+ +D+I Q
Sbjct: 239 GPLVCRRGGGIWILAGITSWVAGCAGGSVPVRNNHVKASLGIFSKVSELMDFITQ 293
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.134 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,549,986
Number of Sequences: 37866
Number of extensions: 675493
Number of successful extensions: 2096
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 168
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1409
Number of HSP's gapped (non-prelim): 195
length of query: 418
length of database: 18,247,518
effective HSP length: 105
effective length of query: 313
effective length of database: 14,271,588
effective search space: 4467007044
effective search space used: 4467007044
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.