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Search of human proteins with 4507161
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4507161 SRY-box 11 [Homo sapiens]
(441 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4507161 SRY-box 11 [Homo sapiens] 885 0.0
gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens] 291 1e-78
gi|21264339 SRY (sex determining region Y)-box 12 [Homo sapiens] 223 2e-58
gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens] 139 4e-33
gi|5902108 SRY-box 21 [Homo sapiens] 134 2e-31
gi|5902106 SRY-box 15 [Homo sapiens] 124 1e-28
gi|30061556 SRY (sex determining region Y)-box 3 [Homo sapiens] 123 3e-28
gi|28195386 sex-determining region Y-box 2 [Homo sapiens] 123 4e-28
gi|4759162 SRY-box 14 [Homo sapiens] 122 5e-28
gi|13899269 SRY-box 7 [Homo sapiens] 120 3e-27
gi|30179903 SRY (sex determining region Y)-box 8 [Homo sapiens] 119 4e-27
gi|5902104 SRY (sex determining region Y)-box 10 [Homo sapiens] 115 8e-26
gi|4557853 transcription factor SOX9 [Homo sapiens] 115 1e-25
gi|11967991 SRY-box 17 [Homo sapiens] 115 1e-25
gi|8924248 SRY-box 18 [Homo sapiens] 111 1e-24
gi|41406089 SRY-box 13 [Homo sapiens] 107 2e-23
gi|30061558 SRY (sex determining region Y)-box 5 isoform c [Homo... 105 8e-23
gi|23308715 SRY (sex determining region Y)-box 5 isoform b [Homo... 105 8e-23
gi|23308713 SRY (sex determining region Y)-box 5 isoform a [Homo... 105 8e-23
gi|4507225 sex determining region Y [Homo sapiens] 105 1e-22
gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Hom... 103 4e-22
gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Hom... 103 4e-22
gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo... 103 4e-22
gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo... 103 4e-22
gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo... 86 5e-17
gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Hom... 86 5e-17
gi|112421108 capicua homolog [Homo sapiens] 70 4e-12
gi|226371627 transcription factor 7-like 2 isoform 6 [Homo sapiens] 59 7e-09
gi|226371620 transcription factor 7-like 2 isoform 3 [Homo sapiens] 59 7e-09
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ... 59 9e-09
>gi|4507161 SRY-box 11 [Homo sapiens]
Length = 441
Score = 885 bits (2287), Expect = 0.0
Identities = 441/441 (100%), Positives = 441/441 (100%)
Query: 1 MVQQAESLEAESNLPREALDTEEGEFMACSPVALDESDPDWCKTASGHIKRPMNAFMVWS 60
MVQQAESLEAESNLPREALDTEEGEFMACSPVALDESDPDWCKTASGHIKRPMNAFMVWS
Sbjct: 1 MVQQAESLEAESNLPREALDTEEGEFMACSPVALDESDPDWCKTASGHIKRPMNAFMVWS 60
Query: 61 KIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRLKHMADYPDYKYRP 120
KIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRLKHMADYPDYKYRP
Sbjct: 61 KIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRLKHMADYPDYKYRP 120
Query: 121 RKKPKMDPSAKPSASQSPEKSAAGGGGGSAGGGAGGAKTSKGSSKKCGKLKAPAAAGAKA 180
RKKPKMDPSAKPSASQSPEKSAAGGGGGSAGGGAGGAKTSKGSSKKCGKLKAPAAAGAKA
Sbjct: 121 RKKPKMDPSAKPSASQSPEKSAAGGGGGSAGGGAGGAKTSKGSSKKCGKLKAPAAAGAKA 180
Query: 181 GAGKAAQSGDYGGAGDDYVLGSLRVSGSGGGGAGKTVKCVFLDEDDDDDDDDDELQLQIK 240
GAGKAAQSGDYGGAGDDYVLGSLRVSGSGGGGAGKTVKCVFLDEDDDDDDDDDELQLQIK
Sbjct: 181 GAGKAAQSGDYGGAGDDYVLGSLRVSGSGGGGAGKTVKCVFLDEDDDDDDDDDELQLQIK 240
Query: 241 QEPDEEDEEPPHQQLLQPPGQQPSQLLRRYNVAKVPASPTLSSSAESPEGASLYDEVRAG 300
QEPDEEDEEPPHQQLLQPPGQQPSQLLRRYNVAKVPASPTLSSSAESPEGASLYDEVRAG
Sbjct: 241 QEPDEEDEEPPHQQLLQPPGQQPSQLLRRYNVAKVPASPTLSSSAESPEGASLYDEVRAG 300
Query: 301 ATSGAGGGSRLYYSFKNITKQHPPPLAQPALSPASSRSVSTSSSSSSGSSSGSSGEDADD 360
ATSGAGGGSRLYYSFKNITKQHPPPLAQPALSPASSRSVSTSSSSSSGSSSGSSGEDADD
Sbjct: 301 ATSGAGGGSRLYYSFKNITKQHPPPLAQPALSPASSRSVSTSSSSSSGSSSGSSGEDADD 360
Query: 361 LMFDLSLNFSQSAHSASEQQLGGGAAAGNLSLSLVDKDLDSFSEGSLGSHFEFPDYCTPE 420
LMFDLSLNFSQSAHSASEQQLGGGAAAGNLSLSLVDKDLDSFSEGSLGSHFEFPDYCTPE
Sbjct: 361 LMFDLSLNFSQSAHSASEQQLGGGAAAGNLSLSLVDKDLDSFSEGSLGSHFEFPDYCTPE 420
Query: 421 LSEMIAGDWLEANFSDLVFTY 441
LSEMIAGDWLEANFSDLVFTY
Sbjct: 421 LSEMIAGDWLEANFSDLVFTY 441
>gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens]
Length = 474
Score = 291 bits (744), Expect = 1e-78
Identities = 209/491 (42%), Positives = 258/491 (52%), Gaps = 67/491 (13%)
Query: 1 MVQQAESLE-AESNLPREALDTEEGEFM--ACSPVALDES-------DPDWCKTASGHIK 50
MVQQ + E E+ L E+ D+ G + A SP + DP WCKT SGHIK
Sbjct: 1 MVQQTNNAENTEALLAGESSDSGAGLELGIASSPTPGSTASTGGKADDPSWCKTPSGHIK 60
Query: 51 RPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRLKHM 110
RPMNAFMVWS+IERRKIMEQSPDMHNAEISKRLGKRWK+LKDS+KIPFIREAERLRLKHM
Sbjct: 61 RPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLKDSDKIPFIREAERLRLKHM 120
Query: 111 ADYPDYKYRPRKKPK---MDPSAKPSASQSP----EKSAAGGGGGSAGGGAGGAKTSKGS 163
ADYPDYKYRPRKK K + S+ +AS P +K GGGG GGG GG+ + G
Sbjct: 121 ADYPDYKYRPRKKVKSGNANSSSSAAASSKPGEKGDKVGGSGGGGHGGGGGGGSSNAGGG 180
Query: 164 SKKCGKLKAPAAAGAKAGAGKAAQSGDYGGAGDDYVLGSLRVSGSGGGGAGKTVKCV--- 220
G + A +K K+ S GGAG ++ +GGGG GK
Sbjct: 181 ----GGGASGGGANSKPAQKKSCGSKVAGGAGGGVSKPHAKLILAGGGGGGKAAAAAAAS 236
Query: 221 FLDED---------DDDDDDDDELQLQIKQEPDEEDEEPPHQQLLQPPGQQ--PSQLLRR 269
F E D + + L PG+ ++ R
Sbjct: 237 FAAEQAGAAALLPLGAAADHHSLYKARTPSASASASSAASASAALAAPGKHLAEKKVKRV 296
Query: 270 YNVAKVPASPT----LSSSAESPEGASLYDEVRAG--------------ATSGAGGGSRL 311
Y + S + + + A+ + LY+E AG A+S A G S
Sbjct: 297 YLFGGLGTSSSPVGGVGAGADPSDPLGLYEEEGAGCSPDAPSLSGRSSAASSPAAGRSPA 356
Query: 312 -YYSFKNITKQHPPPLAQPALSPASSRSVSTSSSSSSGSSSGSSGEDADDLMFDLSLNFS 370
+ + ++ P P + P S ASS + S SSSSSS SS S E DDL L LN S
Sbjct: 357 DHRGYASLRAASPAPSSAP--SHASSSASSHSSSSSSSGSSSSDDEFEDDL---LDLNPS 411
Query: 371 QSAHSASEQQLGGGAAAGNLSLSLVDKDLDSFSEGSLGSHFEFPDYCTPELSEMIAGDWL 430
+ S S LG + S S +D+DLD E GSHFEFPDYCTPE+SEMI+GDWL
Sbjct: 412 SNFESMS---LGSFS-----SSSALDRDLDFNFEPGSGSHFEFPDYCTPEVSEMISGDWL 463
Query: 431 EANFSDLVFTY 441
E++ S+LVFTY
Sbjct: 464 ESSISNLVFTY 474
>gi|21264339 SRY (sex determining region Y)-box 12 [Homo sapiens]
Length = 315
Score = 223 bits (569), Expect = 2e-58
Identities = 156/405 (38%), Positives = 195/405 (48%), Gaps = 119/405 (29%)
Query: 38 DPDWCKTASGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIP 97
+P WCKT SGHIKRPMNAFMVWS+ ERRKIM+Q PDMHNAEISKRLG+RW++L+DSEKIP
Sbjct: 29 EPGWCKTPSGHIKRPMNAFMVWSQHERRKIMDQWPDMHNAEISKRLGRRWQLLQDSEKIP 88
Query: 98 FIREAERLRLKHMADYPDYKYRPRKKPKMDPS-AKPSASQSPEKSAAGGGGGSAGGGAGG 156
F+REAERLRLKHMADYPDYKYRPRKK K P+ A+P GG GG
Sbjct: 89 FVREAERLRLKHMADYPDYKYRPRKKSKGAPAKARPR---------------PPGGSGGG 133
Query: 157 AKTSKGSSKKCGKLKAPAAAGAKAGAGKAAQSGDYGGAGDDYVLGSLRVSGSGGGGAGKT 216
++ G + P G +A G GGG A
Sbjct: 134 SRLKPGP-------QLPGRGGRRAAGGPL-----------------------GGGAAA-- 161
Query: 217 VKCVFLDEDDDDDDDDDELQLQIKQEPDEEDEEPPHQQLLQPPGQQPSQLLRRYNVAKVP 276
EDDD+DDD++ L++ +L++ PG++ ++ VP
Sbjct: 162 ------PEDDDEDDDEELLEV----------------RLVETPGRELWRM--------VP 191
Query: 277 ASPTLSSSAESPEGASLYDEVRAGATSGAGGGSRLYYSFKNITKQHPPPLAQPALSPASS 336
A AE RA SG G A A SP S
Sbjct: 192 AGRAARGQAE-----------RAQGPSGEGAA------------------AAAAASPTPS 222
Query: 337 RSVSTSSSSSSGSSSGSSGEDADDLMFDLSLNFSQSAHSASEQQLGGGAAAGNLSLSLVD 396
+++ GE+ + SL F +L G A L S +D
Sbjct: 223 EDEEPEEEEEE-AAAAEEGEEETVASGEESLGFL--------SRLPPGPA--GLDCSALD 271
Query: 397 KDLDSFSEGSLGSHFEFPDYCTPELSEMIAGDWLEANFSDLVFTY 441
+D D S SHFEFPDYCTPE++EMIAGDW ++ +DLVFTY
Sbjct: 272 RDPD-LQPPSGTSHFEFPDYCTPEVTEMIAGDWRPSSIADLVFTY 315
>gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens]
Length = 391
Score = 139 bits (351), Expect = 4e-33
Identities = 104/322 (32%), Positives = 140/322 (43%), Gaps = 52/322 (16%)
Query: 43 KTASGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREA 102
K +KRPMNAFMVWS+ +RRK+ +++P MHN+EISKRLG WK++ ++EK PFI EA
Sbjct: 45 KANQDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFIDEA 104
Query: 103 ERLRLKHMADYPDYKYRPRKKPKMDPSAKPSASQSPEKSAAGGGGGSAGGGAGGAKTSKG 162
+RLR HM ++PDYKYRPR+K K +K + GG +AG G GGA + G
Sbjct: 105 KRLRALHMKEHPDYKYRPRRKTK--------TLLKKDKYSLAGGLLAAGAGGGGAAVAMG 156
Query: 163 SSKKCGKLKAPAAAGAKAGAGKAAQSGDYGGAGDDYVLGSLRVSGSGGGGAGKTVKCVFL 222
GA A + G G G +V G + G A +
Sbjct: 157 ---------VGVGVGAAAVGQRLESPGGAAGGGYAHVNGWANGAYPGSVAAAAAAAAMM- 206
Query: 223 DEDDDDDDDDDELQLQIKQEPDEEDEEP--------PHQQLLQPPGQQPSQLLRRYNVAK 274
E QL Q P P PH P QP + RY++
Sbjct: 207 ----------QEAQLAYGQHPGAGGAHPHAHPAHPHPHHPHAHPHNPQP---MHRYDMGA 253
Query: 275 VPASPTLSSS---AESPEGASLYDEVRAGATSGAGGGSRLYYSFKNITKQHPPPLAQPAL 331
+ SP +S + SP G A A + A GG+ Q+ A A
Sbjct: 254 LQYSPISNSQGYMSASPSGYGGLPYGAAAAAAAAAGGAH----------QNSAVAAAAAA 303
Query: 332 SPASSRSVSTSSSSSSGSSSGS 353
+ ASS ++ S SGS
Sbjct: 304 AAASSGALGALGSLVKSEPSGS 325
Score = 36.6 bits (83), Expect = 0.047
Identities = 15/35 (42%), Positives = 20/35 (57%)
Query: 132 PSASQSPEKSAAGGGGGSAGGGAGGAKTSKGSSKK 166
P+ P + GGGGG GGG GGAK ++ K+
Sbjct: 19 PTNLSGPAGAGGGGGGGGGGGGGGGAKANQDRVKR 53
>gi|5902108 SRY-box 21 [Homo sapiens]
Length = 276
Score = 134 bits (337), Expect = 2e-31
Identities = 73/161 (45%), Positives = 97/161 (60%), Gaps = 19/161 (11%)
Query: 48 HIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRL 107
H+KRPMNAFMVWS+ +RRK+ +++P MHN+EISKRLG WK+L +SEK PFI EA+RLR
Sbjct: 7 HVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRA 66
Query: 108 KHMADYPDYKYRPRKKP----KMDPSAKP--------SASQSPEKSAAGGGGGSAGGG-- 153
HM ++PDYKYRPR+KP K D A P + ++ P A G AGGG
Sbjct: 67 MHMKEHPDYKYRPRRKPKTLLKKDKFAFPVPYGLGGVADAEHPALKAGAGLHAGAGGGLV 126
Query: 154 -----AGGAKTSKGSSKKCGKLKAPAAAGAKAGAGKAAQSG 189
A K + ++ ++ P +A A A A AA +G
Sbjct: 127 PESLLANPEKAAAAAAAAAARVFFPQSAAAAAAAAAAAAAG 167
>gi|5902106 SRY-box 15 [Homo sapiens]
Length = 233
Score = 124 bits (312), Expect = 1e-28
Identities = 60/114 (52%), Positives = 79/114 (69%), Gaps = 10/114 (8%)
Query: 49 IKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRLK 108
+KRPMNAFMVWS +RR++ +Q+P MHN+EISKRLG +WK+L + EK PF+ EA+RLR +
Sbjct: 49 VKRPMNAFMVWSSAQRRQMAQQNPKMHNSEISKRLGAQWKLLDEDEKRPFVEEAKRLRAR 108
Query: 109 HMADYPDYKYRPRKKPKMDPSAKPSASQSPEKSAAGGGGGSAGG---GAGGAKT 159
H+ DYPDYKYRPR+K K S+ P + G G ++GG G G A T
Sbjct: 109 HLRDYPDYKYRPRRKAK-------SSGAGPSRCGQGRGNLASGGPLWGPGYATT 155
>gi|30061556 SRY (sex determining region Y)-box 3 [Homo sapiens]
Length = 446
Score = 123 bits (309), Expect = 3e-28
Identities = 101/316 (31%), Positives = 138/316 (43%), Gaps = 85/316 (26%)
Query: 44 TASGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAE 103
T +KRPMNAFMVWS+ +RRK+ ++P MHN+EISKRLG WK+L D+EK PFI EA+
Sbjct: 134 TDQDRVKRPMNAFMVWSRGQRRKMALENPKMHNSEISKRLGADWKLLTDAEKRPFIDEAK 193
Query: 104 RLRLKHMADYPDYKYRPRKKP----KMDPSAKPSASQSPEKSAAGGGGGSAGGGAGGAKT 159
RLR HM +YPDYKYRPR+K K D + PS P G +A A A
Sbjct: 194 RLRAVHMKEYPDYKYRPRRKTKTLLKKDKYSLPSGLLPP--------GAAAAAAAAAA-- 243
Query: 160 SKGSSKKCGKLKAPAAAGAKAGAGKAAQSGDYGGAGDDYVLGSLRVSGSGGGGAGKTVKC 219
A AAA + G G+ D Y V+G G
Sbjct: 244 ------------AAAAASSPVGVGQRL---------DTYT----HVNGWANGAYSLV--- 275
Query: 220 VFLDEDDDDDDDDDELQLQIKQEPDEEDEEPPHQQLLQPPGQQPSQLLRRYNVAKVPASP 279
+ QL Q P P PP P + RY++A + SP
Sbjct: 276 --------------QEQLGYAQPPSMSSPPP-------PPALPP---MHRYDMAGLQYSP 311
Query: 280 TLSSSAESPEGASLYDEVRAGATSGAGGGSRLYYSFKNITKQHPPPLAQPALSPASSRSV 339
+ P GA Y V A A + +G G P A A + A +
Sbjct: 312 MM------PPGAQSYMNVAAAAAAASGYGGM-------------APSATAAAAAAYGQQP 352
Query: 340 STSSSSSSGSSSGSSG 355
+T++++++ +++ S G
Sbjct: 353 ATAAAAAAAAAAMSLG 368
Score = 32.3 bits (72), Expect = 0.88
Identities = 24/59 (40%), Positives = 27/59 (45%), Gaps = 14/59 (23%)
Query: 142 AAGGGGGSAGGGAGGAKTSKGSSKKCGKLKAPAAAGAKAGAGKA-AQSGDYGGAGDDYV 199
AAG GG +A GGA GK A AA GA +G G + SG GG D V
Sbjct: 94 AAGTGGPAAPGGA-------------GKSSANAAGGANSGGGSSGGASGGGGGTDQDRV 139
Score = 29.6 bits (65), Expect = 5.7
Identities = 21/69 (30%), Positives = 27/69 (39%), Gaps = 8/69 (11%)
Query: 124 PKMDPSAKPSASQSPEKSAAGGGGGSAGGGAGGAKTSKGSSKKCGKLKAPAAAGAKAGAG 183
P M P A+ + + +AA G GG A A + G + PA A A A A
Sbjct: 311 PMMPPGAQSYMNVAAAAAAASGYGGMAPSATAAAAAAYG--------QQPATAAAAAAAA 362
Query: 184 KAAQSGDYG 192
A G G
Sbjct: 363 AAMSLGPMG 371
>gi|28195386 sex-determining region Y-box 2 [Homo sapiens]
Length = 317
Score = 123 bits (308), Expect = 4e-28
Identities = 63/118 (53%), Positives = 80/118 (67%), Gaps = 5/118 (4%)
Query: 43 KTASGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREA 102
K + +KRPMNAFMVWS+ +RRK+ +++P MHN+EISKRLG WK+L ++EK PFI EA
Sbjct: 35 KNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEA 94
Query: 103 ERLRLKHMADYPDYKYRPRKKP----KMDPSAKPSASQSP-EKSAAGGGGGSAGGGAG 155
+RLR HM ++PDYKYRPR+K K D P +P S A G G AG GAG
Sbjct: 95 KRLRALHMKEHPDYKYRPRRKTKTLMKKDKYTLPGGLLAPGGNSMASGVGVGAGLGAG 152
>gi|4759162 SRY-box 14 [Homo sapiens]
Length = 240
Score = 122 bits (307), Expect = 5e-28
Identities = 53/80 (66%), Positives = 69/80 (86%)
Query: 46 SGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERL 105
S HIKRPMNAFMVWS+ +RRK+ +++P MHN+EISKRLG WK+L ++EK P+I EA+RL
Sbjct: 5 SDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKRL 64
Query: 106 RLKHMADYPDYKYRPRKKPK 125
R +HM ++PDYKYRPR+KPK
Sbjct: 65 RAQHMKEHPDYKYRPRRKPK 84
>gi|13899269 SRY-box 7 [Homo sapiens]
Length = 388
Score = 120 bits (300), Expect = 3e-27
Identities = 74/180 (41%), Positives = 96/180 (53%), Gaps = 41/180 (22%)
Query: 18 ALDTEEGEFMACSPVALDESDPDWCKTASGHIKRPMNAFMVWSKIERRKIMEQSPDMHNA 77
ALD E + SP A+ D K + I+RPMNAFMVW+K ER+++ Q+PD+HNA
Sbjct: 18 ALDAELSDGQ--SPPAVPRPPGD--KGSESRIRRPMNAFMVWAKDERKRLAVQNPDLHNA 73
Query: 78 EISKRLGKRWKMLKDSEKIPFIREAERLRLKHMADYPDYKYRPRKK-------PKMDP-- 128
E+SK LGK WK L S+K P++ EAERLRL+HM DYP+YKYRPR+K ++DP
Sbjct: 74 ELSKMLGKSWKALTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRRKKQAKRLCKRVDPGF 133
Query: 129 ---SAKPSASQSPEKSAAGGGG-------------------------GSAGGGAGGAKTS 160
S + PEK + G G AGGG GG +S
Sbjct: 134 LLSSLSRDQNALPEKRSGSRGALGEKEDRGEYSPGTALPSLRGCYHEGPAGGGGGGTPSS 193
>gi|30179903 SRY (sex determining region Y)-box 8 [Homo sapiens]
Length = 446
Score = 119 bits (299), Expect = 4e-27
Identities = 64/149 (42%), Positives = 84/149 (56%), Gaps = 27/149 (18%)
Query: 45 ASGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAER 104
A H+KRPMNAFMVW++ RRK+ +Q P +HNAE+SK LGK W++L +SEK PF+ EAER
Sbjct: 98 AKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAER 157
Query: 105 LRLKHMADYPDYKYRPRKKPKMDPSAKPSASQSPEKSAAGGGGGSAGGGAGGAKTSKGSS 164
LR++H D+PDYKY+PR++ KSA G S G G G+
Sbjct: 158 LRVQHKKDHPDYKYQPRRR----------------KSAKAGHSDSDSGAELGPHPGGGAV 201
Query: 165 KKCGKLKAPAAAGAKAGAGKAAQSGDYGG 193
K A+AG G GD+ G
Sbjct: 202 YK-----------AEAGLGDGHHHGDHTG 219
>gi|5902104 SRY (sex determining region Y)-box 10 [Homo sapiens]
Length = 466
Score = 115 bits (288), Expect = 8e-26
Identities = 52/99 (52%), Positives = 72/99 (72%), Gaps = 2/99 (2%)
Query: 48 HIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRL 107
H+KRPMNAFMVW++ RRK+ +Q P +HNAE+SK LGK W++L +S+K PFI EAERLR+
Sbjct: 103 HVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESDKRPFIEEAERLRM 162
Query: 108 KHMADYPDYKYRPRKKPKMDPSAKPSASQSPEKSAAGGG 146
+H D+PDYKY+PR+ + + A ++ P A GG
Sbjct: 163 QHKKDHPDYKYQPRR--RKNGKAAQGEAECPGGEAEQGG 199
>gi|4557853 transcription factor SOX9 [Homo sapiens]
Length = 509
Score = 115 bits (287), Expect = 1e-25
Identities = 50/94 (53%), Positives = 73/94 (77%), Gaps = 1/94 (1%)
Query: 48 HIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRL 107
H+KRPMNAFMVW++ RRK+ +Q P +HNAE+SK LGK W++L +SEK PF+ EAERLR+
Sbjct: 104 HVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRV 163
Query: 108 KHMADYPDYKYRPRKKPKMDPSAKPSASQSPEKS 141
+H D+PDYKY+PR++ K + + A ++ E++
Sbjct: 164 QHKKDHPDYKYQPRRR-KSVKNGQAEAEEATEQT 196
>gi|11967991 SRY-box 17 [Homo sapiens]
Length = 414
Score = 115 bits (287), Expect = 1e-25
Identities = 53/105 (50%), Positives = 75/105 (71%), Gaps = 5/105 (4%)
Query: 49 IKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRLK 108
I+RPMNAFMVW+K ER+++ +Q+PD+HNAE+SK LGK WK L +EK PF+ EAERLR++
Sbjct: 68 IRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWKALTLAEKRPFVEEAERLRVQ 127
Query: 109 HMADYPDYKYRPRKKPKMDPSAKPSAS-----QSPEKSAAGGGGG 148
HM D+P+YKYRPR++ ++ + P+ +A G GG
Sbjct: 128 HMQDHPNYKYRPRRRKQVKRLKRVEGGFLHGLAEPQAAALGPEGG 172
>gi|8924248 SRY-box 18 [Homo sapiens]
Length = 384
Score = 111 bits (278), Expect = 1e-24
Identities = 47/75 (62%), Positives = 64/75 (85%)
Query: 49 IKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRLK 108
I+RPMNAFMVW+K ER+++ +Q+PD+HNA +SK LGK WK L +EK PF+ EAERLR++
Sbjct: 85 IRRPMNAFMVWAKDERKRLAQQNPDLHNAVLSKMLGKAWKELNAAEKRPFVEEAERLRVQ 144
Query: 109 HMADYPDYKYRPRKK 123
H+ D+P+YKYRPR+K
Sbjct: 145 HLRDHPNYKYRPRRK 159
>gi|41406089 SRY-box 13 [Homo sapiens]
Length = 622
Score = 107 bits (268), Expect = 2e-23
Identities = 48/78 (61%), Positives = 58/78 (74%)
Query: 46 SGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERL 105
S HIKRPMNAFMVW+K ERRKI++ PDMHN+ ISK LG RWK + + EK P+ E RL
Sbjct: 421 SSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQARL 480
Query: 106 RLKHMADYPDYKYRPRKK 123
+H+ YPDYKY+PR K
Sbjct: 481 SRQHLEKYPDYKYKPRPK 498
>gi|30061558 SRY (sex determining region Y)-box 5 isoform c [Homo
sapiens]
Length = 377
Score = 105 bits (262), Expect = 8e-23
Identities = 47/76 (61%), Positives = 57/76 (75%)
Query: 48 HIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRL 107
HIKRPMNAFMVW+K ERRKI++ PDMHN+ ISK LG RWK + + EK P+ E RL
Sbjct: 169 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSK 228
Query: 108 KHMADYPDYKYRPRKK 123
+H+ YPDYKY+PR K
Sbjct: 229 QHLEKYPDYKYKPRPK 244
>gi|23308715 SRY (sex determining region Y)-box 5 isoform b [Homo
sapiens]
Length = 750
Score = 105 bits (262), Expect = 8e-23
Identities = 47/76 (61%), Positives = 57/76 (75%)
Query: 48 HIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRL 107
HIKRPMNAFMVW+K ERRKI++ PDMHN+ ISK LG RWK + + EK P+ E RL
Sbjct: 542 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSK 601
Query: 108 KHMADYPDYKYRPRKK 123
+H+ YPDYKY+PR K
Sbjct: 602 QHLEKYPDYKYKPRPK 617
>gi|23308713 SRY (sex determining region Y)-box 5 isoform a [Homo
sapiens]
Length = 763
Score = 105 bits (262), Expect = 8e-23
Identities = 47/76 (61%), Positives = 57/76 (75%)
Query: 48 HIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRL 107
HIKRPMNAFMVW+K ERRKI++ PDMHN+ ISK LG RWK + + EK P+ E RL
Sbjct: 555 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSK 614
Query: 108 KHMADYPDYKYRPRKK 123
+H+ YPDYKY+PR K
Sbjct: 615 QHLEKYPDYKYKPRPK 630
>gi|4507225 sex determining region Y [Homo sapiens]
Length = 204
Score = 105 bits (261), Expect = 1e-22
Identities = 46/80 (57%), Positives = 64/80 (80%)
Query: 49 IKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRLK 108
+KRPMNAF+VWS+ +RRK+ ++P M N+EISK+LG +WKML ++EK PF +EA++L+
Sbjct: 60 VKRPMNAFIVWSRDQRRKMALENPRMRNSEISKQLGYQWKMLTEAEKWPFFQEAQKLQAM 119
Query: 109 HMADYPDYKYRPRKKPKMDP 128
H YP+YKYRPR+K KM P
Sbjct: 120 HREKYPNYKYRPRRKAKMLP 139
>gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Homo
sapiens]
Length = 841
Score = 103 bits (256), Expect = 4e-22
Identities = 46/76 (60%), Positives = 56/76 (73%)
Query: 48 HIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRL 107
HIKRPMNAFMVW+K ERRKI++ PDMHN+ ISK LG RWK + + EK P+ E RL
Sbjct: 633 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSK 692
Query: 108 KHMADYPDYKYRPRKK 123
H+ YP+YKY+PR K
Sbjct: 693 IHLEKYPNYKYKPRPK 708
>gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Homo
sapiens]
Length = 801
Score = 103 bits (256), Expect = 4e-22
Identities = 46/76 (60%), Positives = 56/76 (73%)
Query: 48 HIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRL 107
HIKRPMNAFMVW+K ERRKI++ PDMHN+ ISK LG RWK + + EK P+ E RL
Sbjct: 593 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSK 652
Query: 108 KHMADYPDYKYRPRKK 123
H+ YP+YKY+PR K
Sbjct: 653 IHLEKYPNYKYKPRPK 668
>gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo
sapiens]
Length = 804
Score = 103 bits (256), Expect = 4e-22
Identities = 46/76 (60%), Positives = 56/76 (73%)
Query: 48 HIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRL 107
HIKRPMNAFMVW+K ERRKI++ PDMHN+ ISK LG RWK + + EK P+ E RL
Sbjct: 596 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSK 655
Query: 108 KHMADYPDYKYRPRKK 123
H+ YP+YKY+PR K
Sbjct: 656 IHLEKYPNYKYKPRPK 671
>gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo
sapiens]
Length = 808
Score = 103 bits (256), Expect = 4e-22
Identities = 46/76 (60%), Positives = 56/76 (73%)
Query: 48 HIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRL 107
HIKRPMNAFMVW+K ERRKI++ PDMHN+ ISK LG RWK + + EK P+ E RL
Sbjct: 600 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSK 659
Query: 108 KHMADYPDYKYRPRKK 123
H+ YP+YKY+PR K
Sbjct: 660 IHLEKYPNYKYKPRPK 675
>gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo
sapiens]
Length = 501
Score = 86.3 bits (212), Expect = 5e-17
Identities = 36/84 (42%), Positives = 57/84 (67%)
Query: 38 DPDWCKTASGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIP 97
D + K +GH+KRPMNAFMVW++I R + + +P +NAEIS +LG W L + +K P
Sbjct: 326 DTPFSKDRNGHVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKP 385
Query: 98 FIREAERLRLKHMADYPDYKYRPR 121
+ EA++++ KH ++P + Y+PR
Sbjct: 386 YYDEAQKIKEKHREEFPGWVYQPR 409
>gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Homo
sapiens]
Length = 753
Score = 86.3 bits (212), Expect = 5e-17
Identities = 36/84 (42%), Positives = 57/84 (67%)
Query: 38 DPDWCKTASGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIP 97
D + K +GH+KRPMNAFMVW++I R + + +P +NAEIS +LG W L + +K P
Sbjct: 326 DTPFSKDRNGHVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKP 385
Query: 98 FIREAERLRLKHMADYPDYKYRPR 121
+ EA++++ KH ++P + Y+PR
Sbjct: 386 YYDEAQKIKEKHREEFPGWVYQPR 409
>gi|112421108 capicua homolog [Homo sapiens]
Length = 1608
Score = 70.1 bits (170), Expect = 4e-12
Identities = 96/407 (23%), Positives = 153/407 (37%), Gaps = 88/407 (21%)
Query: 43 KTASGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREA 102
K HI+RPMNAFM++SK R + ++ P+ N +SK LG+ W L EK + A
Sbjct: 194 KREKDHIRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLA 253
Query: 103 ERLRLKHMADYPDYKYRPRKKPKMDPSAKPSA-------SQSPEKSAAGGGGGSAGGGAG 155
+++ H +PD+K+ + + K AKP++ ++ E+S + G +A G +
Sbjct: 254 FQVKEAHFKAHPDWKWCNKDRKKSSSEAKPTSLGLAGGHKETRERSMSETGTAAAPGVSS 313
Query: 156 -----------GAKTSKGSSKKCG-----KLKAPAAAGAKAGAGKAAQSGDYGGAGDDYV 199
+ T S CG + P +A +A + S D GG D
Sbjct: 314 ELLSVAAQTLLSSDTKAPGSSSCGAERLHTVGGPGSARPRAFSHSGVHSLD-GGEVDSQA 372
Query: 200 LGSLRVSGSG------------------------GGGAGKTVKCVFL-------DEDDDD 228
L L SG GG T + L +
Sbjct: 373 LQELTQMVSGPASYSGPKPSTQYGAPGPFAAPGEGGALAATGRPPLLPTRASRSQRAASE 432
Query: 229 DDDDDELQLQIKQEPDEEDEEPPHQQLLQPPGQQPSQLLRRYNVAKVPASPTLSSSAESP 288
D DE ++ I +E ++D ++ G + + + +V S + SS E P
Sbjct: 433 DMTSDEERMVICEEEGDDD-------VIADDGFGTTDIDLKCK-ERVTDSESGDSSGEDP 484
Query: 289 EGASLYDEVRAGATSGAGGGSRLY-----YSFKNITKQHPPPLAQPALSPASSRSVSTSS 343
EG G G +++ SF + P P P + S+
Sbjct: 485 EG-------------NKGFGRKVFSPVIRSSFTHCRPPLDPEPPGPPDPPVAFGKGYGSA 531
Query: 344 SSSSGSSSGSSGEDADDLMFDLSLNFSQSAHSASEQQLGGGAAAGNL 390
SSS SS SS A + +FS + + Q+ G G+ AG L
Sbjct: 532 PSSSASSPASSSASA-------ATSFSLGSGTFKAQESGQGSTAGPL 571
>gi|226371627 transcription factor 7-like 2 isoform 6 [Homo sapiens]
Length = 442
Score = 59.3 bits (142), Expect = 7e-09
Identities = 33/97 (34%), Positives = 51/97 (52%), Gaps = 2/97 (2%)
Query: 48 HIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRL 107
HIK+P+NAFM++ K R K++ + +A I++ LG+RW L E+ + A + R
Sbjct: 326 HIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQ 385
Query: 108 KHMADYPDYKYRPR--KKPKMDPSAKPSASQSPEKSA 142
HM YP + R KK K +P + +KSA
Sbjct: 386 LHMQLYPGWSARDNYGKKKKRKRDKQPGETNGEKKSA 422
>gi|226371620 transcription factor 7-like 2 isoform 3 [Homo sapiens]
Length = 489
Score = 59.3 bits (142), Expect = 7e-09
Identities = 33/97 (34%), Positives = 51/97 (52%), Gaps = 2/97 (2%)
Query: 48 HIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRL 107
HIK+P+NAFM++ K R K++ + +A I++ LG+RW L E+ + A + R
Sbjct: 373 HIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQ 432
Query: 108 KHMADYPDYKYRPR--KKPKMDPSAKPSASQSPEKSA 142
HM YP + R KK K +P + +KSA
Sbjct: 433 LHMQLYPGWSARDNYGKKKKRKRDKQPGETNGEKKSA 469
>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2
[Homo sapiens]
Length = 2191
Score = 58.9 bits (141), Expect = 9e-09
Identities = 72/253 (28%), Positives = 93/253 (36%), Gaps = 32/253 (12%)
Query: 142 AAGGGGGSAGGGAGGAKTSKGSSKKCGKLKAPAAAGAKAGAGKAA---QSGDYGGAGDDY 198
A GGGGG GGG G G G A A A A A A AA G YGG+ Y
Sbjct: 248 AGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGY 307
Query: 199 -VLGSLR------VSGSGGGGAGKTVKCVFLDEDDDDDDDDDELQLQIKQEPDEEDEEPP 251
VL S R + G GGGGA K Q Q P
Sbjct: 308 GVLSSPRQQGGGMMMGPGGGGAASLSKAA-------AGSAAGGFQRFAGQNQHPSGATPT 360
Query: 252 HQQLLQPPGQQPSQLLRRYNVAKVPASPTLSSSAESPEGASLYDEVRAGATSGAGGGSRL 311
QLL PS ++R Y + P SS + P S + +A A A GG +
Sbjct: 361 LNQLL----TSPSPMMRSYG----GSYPEYSSPSAPPPPPS-QPQSQAAAAGAAAGGQQA 411
Query: 312 YYSF---KNITKQHPPPLAQPALSPASSRSVSTSSSSSSGSSSG-SSGEDADDLMFDLSL 367
K++ Q+ A PA + A RS S + G + G S G D ++
Sbjct: 412 AAGMGLGKDMGAQY--AAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQ 469
Query: 368 NFSQSAHSASEQQ 380
+ ++ S+ Q
Sbjct: 470 LYGMGSNPHSQPQ 482
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.127 0.364
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,932,622
Number of Sequences: 37866
Number of extensions: 1125830
Number of successful extensions: 24123
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 638
Number of HSP's successfully gapped in prelim test: 628
Number of HSP's that attempted gapping in prelim test: 11900
Number of HSP's gapped (non-prelim): 7512
length of query: 441
length of database: 18,247,518
effective HSP length: 105
effective length of query: 336
effective length of database: 14,271,588
effective search space: 4795253568
effective search space used: 4795253568
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.