Guide to the Human Genome
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Search of human proteins with 4505623

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4505623 pre-B-cell leukemia homeobox 1 [Homo sapiens]
         (430 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4505623 pre-B-cell leukemia homeobox 1 [Homo sapiens]              855   0.0  
gi|5453852 pre-B-cell leukemia homeobox 3 isoform 1 [Homo sapiens]    712   0.0  
gi|27436887 pre-B-cell leukemia homeobox 2 [Homo sapiens]             634   0.0  
gi|198041755 pre-B-cell leukemia homeobox 3 isoform 2 [Homo sapi...   630   0.0  
gi|15149472 pre-B-cell leukemia homeobox 4 [Homo sapiens]             490   e-139
gi|57863279 Meis1, myeloid ecotropic viral integration site 1 ho...    64   3e-10
gi|27502383 Meis homeobox 2 isoform h [Homo sapiens]                   63   5e-10
gi|27502381 Meis homeobox 2 isoform g [Homo sapiens]                   63   5e-10
gi|24762244 Meis homeobox 2 isoform a [Homo sapiens]                   63   5e-10
gi|24762250 Meis homeobox 2 isoform d [Homo sapiens]                   63   5e-10
gi|24762241 Meis homeobox 2 isoform c [Homo sapiens]                   63   5e-10
gi|24762246 Meis homeobox 2 isoform b [Homo sapiens]                   63   5e-10
gi|24762225 Meis homeobox 2 isoform f [Homo sapiens]                   63   5e-10
gi|4505151 Meis homeobox 1 [Homo sapiens]                              63   6e-10
gi|116812644 PBX/knotted 1 homeobox 2 [Homo sapiens]                   60   5e-09
gi|4885597 sine oculis homeobox homolog 3 [Homo sapiens]               59   1e-08
gi|28866955 PBX/knotted 1 homeobox 1 [Homo sapiens]                    59   1e-08
gi|34328941 TGFB-induced factor homeobox 2-like, X-linked [Homo ...    57   4e-08
gi|219275578 SIX homeobox 2 [Homo sapiens]                             54   2e-07
gi|21245108 TGFB-induced factor homeobox 2-like, Y-linked [Homo ...    54   4e-07
gi|28178843 TG-interacting factor isoform a [Homo sapiens]             53   5e-07
gi|4507473 TG-interacting factor isoform c [Homo sapiens]              53   5e-07
gi|28178855 TG-interacting factor isoform d [Homo sapiens]             53   5e-07
gi|28178853 TG-interacting factor isoform d [Homo sapiens]             53   5e-07
gi|28178851 TG-interacting factor isoform d [Homo sapiens]             53   5e-07
gi|28178857 TG-interacting factor isoform d [Homo sapiens]             53   5e-07
gi|28178849 TG-interacting factor isoform c [Homo sapiens]             53   5e-07
gi|28178845 TG-interacting factor isoform b [Homo sapiens]             53   5e-07
gi|11141881 TGFB-induced factor homeobox 2 [Homo sapiens]              52   1e-06
gi|5174681 SIX homeobox 1 [Homo sapiens]                               51   2e-06

>gi|4505623 pre-B-cell leukemia homeobox 1 [Homo sapiens]
          Length = 430

 Score =  855 bits (2209), Expect = 0.0
 Identities = 430/430 (100%), Positives = 430/430 (100%)

Query: 1   MDEQPRLMHSHAGVGMAGHPGLSQHLQDGAGGTEGEGGRKQDIGDILQQIMTITDQSLDE 60
           MDEQPRLMHSHAGVGMAGHPGLSQHLQDGAGGTEGEGGRKQDIGDILQQIMTITDQSLDE
Sbjct: 1   MDEQPRLMHSHAGVGMAGHPGLSQHLQDGAGGTEGEGGRKQDIGDILQQIMTITDQSLDE 60

Query: 61  AQARKHALNCHRMKPALFNVLCEIKEKTVLSIRGAQEEEPTDPQLMRLDNMLLAEGVAGP 120
           AQARKHALNCHRMKPALFNVLCEIKEKTVLSIRGAQEEEPTDPQLMRLDNMLLAEGVAGP
Sbjct: 61  AQARKHALNCHRMKPALFNVLCEIKEKTVLSIRGAQEEEPTDPQLMRLDNMLLAEGVAGP 120

Query: 121 EKGGGSAAAAAAAAASGGAGSDNSVEHSDYRAKLSQIRQIYHTELEKYEQACNEFTTHVM 180
           EKGGGSAAAAAAAAASGGAGSDNSVEHSDYRAKLSQIRQIYHTELEKYEQACNEFTTHVM
Sbjct: 121 EKGGGSAAAAAAAAASGGAGSDNSVEHSDYRAKLSQIRQIYHTELEKYEQACNEFTTHVM 180

Query: 181 NLLREQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNF 240
           NLLREQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNF
Sbjct: 181 NLLREQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNF 240

Query: 241 NKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQE 300
           NKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQE
Sbjct: 241 NKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQE 300

Query: 301 EANIYAAKTAVTATNVSAHGSQANSPSTPNSAGSSSSFNMSNSGDLFMSVQSLNGDSYQG 360
           EANIYAAKTAVTATNVSAHGSQANSPSTPNSAGSSSSFNMSNSGDLFMSVQSLNGDSYQG
Sbjct: 301 EANIYAAKTAVTATNVSAHGSQANSPSTPNSAGSSSSFNMSNSGDLFMSVQSLNGDSYQG 360

Query: 361 AQVGANVQSQVDTLRHVISQTGGYSDGLAASQMYSPQGISANGGWQDATTPSSVTSPTEG 420
           AQVGANVQSQVDTLRHVISQTGGYSDGLAASQMYSPQGISANGGWQDATTPSSVTSPTEG
Sbjct: 361 AQVGANVQSQVDTLRHVISQTGGYSDGLAASQMYSPQGISANGGWQDATTPSSVTSPTEG 420

Query: 421 PGSVHSDTSN 430
           PGSVHSDTSN
Sbjct: 421 PGSVHSDTSN 430


>gi|5453852 pre-B-cell leukemia homeobox 3 isoform 1 [Homo sapiens]
          Length = 434

 Score =  712 bits (1838), Expect = 0.0
 Identities = 366/440 (83%), Positives = 396/440 (90%), Gaps = 16/440 (3%)

Query: 1   MDEQPRLMHSHAGVGMAGHP---GLS----QHLQDGAGGTEGEGGRKQDIGDILQQIMTI 53
           MD+Q R++ + AGV +AGH    G++     H  +GA G     GRKQDIGDIL QIMTI
Sbjct: 1   MDDQSRMLQTLAGVNLAGHSVQGGMALPPPPHGHEGADGD----GRKQDIGDILHQIMTI 56

Query: 54  TDQSLDEAQARKHALNCHRMKPALFNVLCEIKEKTVLSIRGAQEEEPTDPQLMRLDNMLL 113
           TDQSLDEAQA+KHALNCHRMKPALF+VLCEIKEKT LSIRGAQEE+P DPQLMRLDNMLL
Sbjct: 57  TDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRGAQEEDPPDPQLMRLDNMLL 116

Query: 114 AEGVAGPEKGGGSAAAAAAAAASGGAGSDNSVEHSDYRAKLSQIRQIYHTELEKYEQACN 173
           AEGV+GPEKGGGSAAAAAAAAASGG+ SDNS+EHSDYRAKL+QIRQIYHTELEKYEQACN
Sbjct: 117 AEGVSGPEKGGGSAAAAAAAAASGGS-SDNSIEHSDYRAKLTQIRQIYHTELEKYEQACN 175

Query: 174 EFTTHVMNLLREQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSRFLDA 233
           EFTTHVMNLLREQSRTRPISPKEIERMV IIHRKFSSIQMQLKQSTCEAVMILRSRFLDA
Sbjct: 176 EFTTHVMNLLREQSRTRPISPKEIERMVGIIHRKFSSIQMQLKQSTCEAVMILRSRFLDA 235

Query: 234 RRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKK 293
           RRKRRNF+KQATEILNEYFYSHLSNPYPSEEAKEELAKKC ITVSQVSNWFGNKRIRYKK
Sbjct: 236 RRKRRNFSKQATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQVSNWFGNKRIRYKK 295

Query: 294 NIGKFQEEANIYAAKTAVTATNVSA---HGSQANSPSTPNSAGSSSSFNMSNSGDLFMSV 350
           NIGKFQEEAN+YAAKTAVTA +  A     +Q NSP+TPNS GSS SFN+ NSGD+FM++
Sbjct: 296 NIGKFQEEANLYAAKTAVTAAHAVAAAVQNNQTNSPTTPNS-GSSGSFNLPNSGDMFMNM 354

Query: 351 QSLNGDSYQGAQVGANVQSQVDTLRHVISQTGGYSDGLAASQMYSPQGISANGGWQDATT 410
           QSLNGDSYQG+QVGANVQSQVDTLRHVI+QTGGYSDGL  + +YSP  ++ANGGWQDATT
Sbjct: 355 QSLNGDSYQGSQVGANVQSQVDTLRHVINQTGGYSDGLGGNSLYSPHNLNANGGWQDATT 414

Query: 411 PSSVTSPTEGPGSVHSDTSN 430
           PSSVTSPTEGPGSVHSDTSN
Sbjct: 415 PSSVTSPTEGPGSVHSDTSN 434


>gi|27436887 pre-B-cell leukemia homeobox 2 [Homo sapiens]
          Length = 430

 Score =  634 bits (1634), Expect = 0.0
 Identities = 330/419 (78%), Positives = 359/419 (85%), Gaps = 14/419 (3%)

Query: 15  GMAGHPGLSQHLQDGAGGTEG-EGGR-KQDIGDILQQIMTITDQSLDEAQARKHALNCHR 72
           G  G PG      D  GG+ G  GGR KQDIGDILQQIMTITDQSLDEAQA+KHALNCHR
Sbjct: 23  GEPGGPGEPPGGGDPGGGSGGVPGGRGKQDIGDILQQIMTITDQSLDEAQAKKHALNCHR 82

Query: 73  MKPALFNVLCEIKEKTVLSIRGAQEEEPTDPQLMRLDNMLLAEGVAGPEKGGGSAAAAAA 132
           MKPALF+VLCEIKEKT LSIR +QEEEP DPQLMRLDNMLLAEGVAGPEKGGGSAAAAAA
Sbjct: 83  MKPALFSVLCEIKEKTGLSIRSSQEEEPVDPQLMRLDNMLLAEGVAGPEKGGGSAAAAAA 142

Query: 133 AAASGGAGS-DNSVEHSDYRAKLSQIRQIYHTELEKYEQACNEFTTHVMNLLREQSRTRP 191
           AAASGG  S DNS+EHSDYR+KL+QIR IYH+ELEKYEQACNEFTTHVMNLLREQSRTRP
Sbjct: 143 AAASGGGVSPDNSIEHSDYRSKLAQIRHIYHSELEKYEQACNEFTTHVMNLLREQSRTRP 202

Query: 192 ISPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFNKQATEILNEY 251
           ++PKE+ERMVSIIHRKFS+IQMQLKQSTCEAVMILRSRFLDARRKRRNF+KQATE+LNEY
Sbjct: 203 VAPKEMERMVSIIHRKFSAIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATEVLNEY 262

Query: 252 FYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQEEANIYAAKTAV 311
           FYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQEEANIYA KTAV
Sbjct: 263 FYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQEEANIYAVKTAV 322

Query: 312 TATNVSAHGSQANSPSTPNSAGSSSSFNMSNSGDLFMSVQSLNGDSYQGAQVGANVQSQV 371
           + T    H S+ +SP+ P+SAGS  SFN+S SGD+F+ +  LNGDSY          SQV
Sbjct: 323 SVTQ-GGH-SRTSSPTPPSSAGSGGSFNLSGSGDMFLGMPGLNGDSYSA--------SQV 372

Query: 372 DTLRHVISQTGGYSDGLAASQMYSPQGISANGGWQDATTPSSVTSPTEGPGSVHSDTSN 430
           ++LRH +   GGY D L   QMYSP+ + ANG WQ+A TPSSVTSPTEGPGSVHSDTSN
Sbjct: 373 ESLRHSMG-PGGYGDNLGGGQMYSPREMRANGSWQEAVTPSSVTSPTEGPGSVHSDTSN 430


>gi|198041755 pre-B-cell leukemia homeobox 3 isoform 2 [Homo
           sapiens]
          Length = 359

 Score =  630 bits (1624), Expect = 0.0
 Identities = 318/361 (88%), Positives = 339/361 (93%), Gaps = 5/361 (1%)

Query: 73  MKPALFNVLCEIKEKTVLSIRGAQEEEPTDPQLMRLDNMLLAEGVAGPEKGGGSAAAAAA 132
           MKPALF+VLCEIKEKT LSIRGAQEE+P DPQLMRLDNMLLAEGV+GPEKGGGSAAAAAA
Sbjct: 1   MKPALFSVLCEIKEKTGLSIRGAQEEDPPDPQLMRLDNMLLAEGVSGPEKGGGSAAAAAA 60

Query: 133 AAASGGAGSDNSVEHSDYRAKLSQIRQIYHTELEKYEQACNEFTTHVMNLLREQSRTRPI 192
           AAASGG+ SDNS+EHSDYRAKL+QIRQIYHTELEKYEQACNEFTTHVMNLLREQSRTRPI
Sbjct: 61  AAASGGS-SDNSIEHSDYRAKLTQIRQIYHTELEKYEQACNEFTTHVMNLLREQSRTRPI 119

Query: 193 SPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFNKQATEILNEYF 252
           SPKEIERMV IIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNF+KQATEILNEYF
Sbjct: 120 SPKEIERMVGIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATEILNEYF 179

Query: 253 YSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQEEANIYAAKTAVT 312
           YSHLSNPYPSEEAKEELAKKC ITVSQVSNWFGNKRIRYKKNIGKFQEEAN+YAAKTAVT
Sbjct: 180 YSHLSNPYPSEEAKEELAKKCSITVSQVSNWFGNKRIRYKKNIGKFQEEANLYAAKTAVT 239

Query: 313 ATNVSA---HGSQANSPSTPNSAGSSSSFNMSNSGDLFMSVQSLNGDSYQGAQVGANVQS 369
           A +  A     +Q NSP+TPNS GSS SFN+ NSGD+FM++QSLNGDSYQG+QVGANVQS
Sbjct: 240 AAHAVAAAVQNNQTNSPTTPNS-GSSGSFNLPNSGDMFMNMQSLNGDSYQGSQVGANVQS 298

Query: 370 QVDTLRHVISQTGGYSDGLAASQMYSPQGISANGGWQDATTPSSVTSPTEGPGSVHSDTS 429
           QVDTLRHVI+QTGGYSDGL  + +YSP  ++ANGGWQDATTPSSVTSPTEGPGSVHSDTS
Sbjct: 299 QVDTLRHVINQTGGYSDGLGGNSLYSPHNLNANGGWQDATTPSSVTSPTEGPGSVHSDTS 358

Query: 430 N 430
           N
Sbjct: 359 N 359


>gi|15149472 pre-B-cell leukemia homeobox 4 [Homo sapiens]
          Length = 374

 Score =  490 bits (1262), Expect = e-139
 Identities = 259/393 (65%), Positives = 294/393 (74%), Gaps = 34/393 (8%)

Query: 39  RKQDIGDILQQIMTITDQSLDEAQARKHALNCHRMKPALFNVLCEIKEKTVLSIRGAQEE 98
           R+ D  D+LQQIM ITDQSLDEAQARKHALNCHRMKPALF+VLCEIKEKTV+SIRG Q+E
Sbjct: 15  RRLDTSDVLQQIMAITDQSLDEAQARKHALNCHRMKPALFSVLCEIKEKTVVSIRGIQDE 74

Query: 99  EPTDPQLMRLDNMLLAEGVAGPEKGG-GSAAAAAAAAASGGAGSDNSVEHSDYRAKLSQI 157
           +P D QL+RLDNMLLAEGV  PEK G G A A A  A  GG  +DNS+EHSDYRAKLSQI
Sbjct: 75  DPPDAQLLRLDNMLLAEGVCRPEKRGRGGAVARAGTATPGGCPNDNSIEHSDYRAKLSQI 134

Query: 158 RQIYHTELEKYEQACNEFTTHVMNLLREQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQ 217
           RQIYH+ELEKYEQAC EFTTHV NLL+EQSR RP+SPKEIERMV  IH KFS+IQMQLKQ
Sbjct: 135 RQIYHSELEKYEQACREFTTHVTNLLQEQSRMRPVSPKEIERMVGAIHGKFSAIQMQLKQ 194

Query: 218 STCEAVMILRSRFLDARRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITV 277
           STCEAVM LRSR LDARRKRRNF+KQATE+LNEYFYSHL+NPYPSEEAKEELA+K G+T+
Sbjct: 195 STCEAVMTLRSRLLDARRKRRNFSKQATEVLNEYFYSHLNNPYPSEEAKEELARKGGLTI 254

Query: 278 SQVSNWFGNKRIRYKKNIGKFQEEANIYAAKTAVTATNVSAHGSQANSPSTPNSAGSSSS 337
           SQVSNWFGNKRIRYKKN+GKFQEEA IY  KTAV  T V   G+ A+  STP S+GSS  
Sbjct: 255 SQVSNWFGNKRIRYKKNMGKFQEEATIYTGKTAVDTTEVGVPGNHASCLSTP-SSGSSGP 313

Query: 338 FNMSNSGDLFMSVQSLNGDSYQGAQVGANVQSQVDTLRHVISQTGGYSDGLAASQMYSPQ 397
           F + ++GD F+++++L   S Q    G  +QSQ                           
Sbjct: 314 FPLPSAGDAFLTLRTL--ASLQPPPGGGCLQSQ--------------------------- 344

Query: 398 GISANGGWQDATTPSSVTSPTEGPGSVHSDTSN 430
              A G WQ AT   +  SP   PGS++S TSN
Sbjct: 345 ---AQGSWQGATPQPATASPAGDPGSINSSTSN 374


>gi|57863279 Meis1, myeloid ecotropic viral integration site 1
           homolog 3 isoform 2 [Homo sapiens]
          Length = 358

 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 29/56 (51%), Positives = 40/56 (71%)

Query: 235 RKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIR 290
           +KR  F K AT I+  + + HLS+PYPSEE K++LA+  G+T+ QV+NWF N R R
Sbjct: 247 KKRGIFPKVATNIMRAWLFQHLSHPYPSEEQKKQLAQDTGLTILQVNNWFINARRR 302


>gi|27502383 Meis homeobox 2 isoform h [Homo sapiens]
          Length = 306

 Score = 63.2 bits (152), Expect = 5e-10
 Identities = 28/57 (49%), Positives = 41/57 (71%)

Query: 234 RRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIR 290
           ++KR  F K AT I+  + + HL++PYPSEE K++LA+  G+T+ QV+NWF N R R
Sbjct: 189 QKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRR 245


>gi|27502381 Meis homeobox 2 isoform g [Homo sapiens]
          Length = 388

 Score = 63.2 bits (152), Expect = 5e-10
 Identities = 28/57 (49%), Positives = 41/57 (71%)

Query: 234 RRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIR 290
           ++KR  F K AT I+  + + HL++PYPSEE K++LA+  G+T+ QV+NWF N R R
Sbjct: 264 QKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRR 320


>gi|24762244 Meis homeobox 2 isoform a [Homo sapiens]
          Length = 401

 Score = 63.2 bits (152), Expect = 5e-10
 Identities = 28/57 (49%), Positives = 41/57 (71%)

Query: 234 RRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIR 290
           ++KR  F K AT I+  + + HL++PYPSEE K++LA+  G+T+ QV+NWF N R R
Sbjct: 277 QKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRR 333


>gi|24762250 Meis homeobox 2 isoform d [Homo sapiens]
          Length = 470

 Score = 63.2 bits (152), Expect = 5e-10
 Identities = 28/57 (49%), Positives = 41/57 (71%)

Query: 234 RRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIR 290
           ++KR  F K AT I+  + + HL++PYPSEE K++LA+  G+T+ QV+NWF N R R
Sbjct: 277 QKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRR 333


>gi|24762241 Meis homeobox 2 isoform c [Homo sapiens]
          Length = 477

 Score = 63.2 bits (152), Expect = 5e-10
 Identities = 28/57 (49%), Positives = 41/57 (71%)

Query: 234 RRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIR 290
           ++KR  F K AT I+  + + HL++PYPSEE K++LA+  G+T+ QV+NWF N R R
Sbjct: 277 QKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRR 333


>gi|24762246 Meis homeobox 2 isoform b [Homo sapiens]
          Length = 394

 Score = 63.2 bits (152), Expect = 5e-10
 Identities = 28/57 (49%), Positives = 41/57 (71%)

Query: 234 RRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIR 290
           ++KR  F K AT I+  + + HL++PYPSEE K++LA+  G+T+ QV+NWF N R R
Sbjct: 277 QKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRR 333


>gi|24762225 Meis homeobox 2 isoform f [Homo sapiens]
          Length = 381

 Score = 63.2 bits (152), Expect = 5e-10
 Identities = 28/57 (49%), Positives = 41/57 (71%)

Query: 234 RRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIR 290
           ++KR  F K AT I+  + + HL++PYPSEE K++LA+  G+T+ QV+NWF N R R
Sbjct: 264 QKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRR 320


>gi|4505151 Meis homeobox 1 [Homo sapiens]
          Length = 390

 Score = 62.8 bits (151), Expect = 6e-10
 Identities = 28/56 (50%), Positives = 40/56 (71%)

Query: 235 RKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIR 290
           +KR  F K AT I+  + + HL++PYPSEE K++LA+  G+T+ QV+NWF N R R
Sbjct: 274 KKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRR 329


>gi|116812644 PBX/knotted 1 homeobox 2 [Homo sapiens]
          Length = 472

 Score = 59.7 bits (143), Expect = 5e-09
 Identities = 28/81 (34%), Positives = 47/81 (58%)

Query: 210 SIQMQLKQSTCEAVMILRSRFLDARRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEEL 269
           +IQ+Q  Q   +   +L +    ++ KR    K AT I+  + + HL +PYP+E+ K ++
Sbjct: 265 AIQIQNTQVNLDLTSLLDNEDKKSKNKRGVLPKHATNIMRSWLFQHLMHPYPTEDEKRQI 324

Query: 270 AKKCGITVSQVSNWFGNKRIR 290
           A +  +T+ QV+NWF N R R
Sbjct: 325 AAQTNLTLLQVNNWFINARRR 345


>gi|4885597 sine oculis homeobox homolog 3 [Homo sapiens]
          Length = 332

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 41/129 (31%), Positives = 64/129 (49%), Gaps = 8/129 (6%)

Query: 232 DARRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRY 291
           D  +K   F ++   +L E++   L +PYP+   K ELA+  G+T +QV NWF N+R R 
Sbjct: 205 DGEQKTHCFKERTRSLLREWY---LQDPYPNPSKKRELAQATGLTPTQVGNWFKNRRQRD 261

Query: 292 KKNIGK--FQEEANIYAAKTAVTATNVSAHGSQANSPSTPNS--AGSSSSFNMSNSGDLF 347
           +    K   Q +A   +   ++       HGS A SPST  S     SS    +++G   
Sbjct: 262 RAAAAKNRLQHQAIGPSGMRSLAEPGCPTHGS-AESPSTAASPTTSVSSLTERADTGTSI 320

Query: 348 MSVQSLNGD 356
           +SV S + +
Sbjct: 321 LSVTSSDSE 329


>gi|28866955 PBX/knotted 1 homeobox 1 [Homo sapiens]
          Length = 436

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 28/82 (34%), Positives = 48/82 (58%), Gaps = 4/82 (4%)

Query: 209 SSIQMQLKQSTCEAVMILRSRFLDARRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEE 268
           S +Q+QL Q     + IL      ++ KR    K AT ++  + + H+ +PYP+E+ K++
Sbjct: 239 SQLQLQLNQD----LSILHQDDGSSKNKRGVLPKHATNVMRSWLFQHIGHPYPTEDEKKQ 294

Query: 269 LAKKCGITVSQVSNWFGNKRIR 290
           +A +  +T+ QV+NWF N R R
Sbjct: 295 IAAQTNLTLLQVNNWFINARRR 316


>gi|34328941 TGFB-induced factor homeobox 2-like, X-linked [Homo
           sapiens]
          Length = 241

 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 28/100 (28%), Positives = 53/100 (53%)

Query: 234 RRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKK 293
           ++++ N   ++ +IL ++ Y H    YPSEE K+ L++K  +++ Q+SNWF N R R   
Sbjct: 51  KKRKGNLPAESVKILRDWMYKHRFKAYPSEEEKQMLSEKTNLSLLQISNWFINARRRILP 110

Query: 294 NIGKFQEEANIYAAKTAVTATNVSAHGSQANSPSTPNSAG 333
           ++ + +    I   KT   A       ++A+ P+    +G
Sbjct: 111 DMLQQRRNDPIIGHKTGKDAHATHLQSTEASVPAKSGPSG 150


>gi|219275578 SIX homeobox 2 [Homo sapiens]
          Length = 291

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 41/119 (34%), Positives = 64/119 (53%), Gaps = 8/119 (6%)

Query: 240 FNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQ 299
           F +++  +L E+ Y+H  NPYPS   K ELA+  G+T +QVSNWF N+R R +    K +
Sbjct: 131 FKEKSRSVLREW-YAH--NPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKER 187

Query: 300 E--EANIYAAKTAVTATNVSAHGSQAN--SPS-TPNSAGSSSSFNMSNSGDLFMSVQSL 353
           E  E +   +   +  +  S  GS  +  +PS TP+ + SS +  +S       S+ SL
Sbjct: 188 ENNENSNSNSHNPLNGSGKSVLGSSEDEKTPSGTPDHSSSSPALLLSPPPPGLPSLHSL 246


>gi|21245108 TGFB-induced factor homeobox 2-like, Y-linked [Homo
           sapiens]
          Length = 185

 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 26/94 (27%), Positives = 51/94 (54%)

Query: 234 RRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKK 293
           ++++ N   ++ +IL ++ Y H    YPSEE K+ L++K  +++ ++SNWF N R R   
Sbjct: 51  KKRKGNLPAESVKILRDWMYKHRFKAYPSEEEKQMLSEKTNLSLLRISNWFINARRRILP 110

Query: 294 NIGKFQEEANIYAAKTAVTATNVSAHGSQANSPS 327
           ++ + +    I   KT   A       ++A+ P+
Sbjct: 111 DMLQQRRNDPIIGHKTGKDAHATHLQSTEASVPA 144


>gi|28178843 TG-interacting factor isoform a [Homo sapiens]
          Length = 401

 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 24/57 (42%), Positives = 36/57 (63%)

Query: 234 RRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIR 290
           RR+R N  K++ +IL ++ Y H  N YPSE+ K  L+++  ++  QV NWF N R R
Sbjct: 165 RRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRR 221


>gi|4507473 TG-interacting factor isoform c [Homo sapiens]
          Length = 272

 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 24/57 (42%), Positives = 36/57 (63%)

Query: 234 RRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIR 290
           RR+R N  K++ +IL ++ Y H  N YPSE+ K  L+++  ++  QV NWF N R R
Sbjct: 36  RRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRR 92


>gi|28178855 TG-interacting factor isoform d [Homo sapiens]
          Length = 252

 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 24/57 (42%), Positives = 36/57 (63%)

Query: 234 RRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIR 290
           RR+R N  K++ +IL ++ Y H  N YPSE+ K  L+++  ++  QV NWF N R R
Sbjct: 16  RRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRR 72


>gi|28178853 TG-interacting factor isoform d [Homo sapiens]
          Length = 252

 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 24/57 (42%), Positives = 36/57 (63%)

Query: 234 RRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIR 290
           RR+R N  K++ +IL ++ Y H  N YPSE+ K  L+++  ++  QV NWF N R R
Sbjct: 16  RRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRR 72


>gi|28178851 TG-interacting factor isoform d [Homo sapiens]
          Length = 252

 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 24/57 (42%), Positives = 36/57 (63%)

Query: 234 RRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIR 290
           RR+R N  K++ +IL ++ Y H  N YPSE+ K  L+++  ++  QV NWF N R R
Sbjct: 16  RRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRR 72


>gi|28178857 TG-interacting factor isoform d [Homo sapiens]
          Length = 252

 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 24/57 (42%), Positives = 36/57 (63%)

Query: 234 RRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIR 290
           RR+R N  K++ +IL ++ Y H  N YPSE+ K  L+++  ++  QV NWF N R R
Sbjct: 16  RRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRR 72


>gi|28178849 TG-interacting factor isoform c [Homo sapiens]
          Length = 272

 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 24/57 (42%), Positives = 36/57 (63%)

Query: 234 RRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIR 290
           RR+R N  K++ +IL ++ Y H  N YPSE+ K  L+++  ++  QV NWF N R R
Sbjct: 36  RRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRR 92


>gi|28178845 TG-interacting factor isoform b [Homo sapiens]
          Length = 286

 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 24/57 (42%), Positives = 36/57 (63%)

Query: 234 RRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIR 290
           RR+R N  K++ +IL ++ Y H  N YPSE+ K  L+++  ++  QV NWF N R R
Sbjct: 50  RRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRR 106


>gi|11141881 TGFB-induced factor homeobox 2 [Homo sapiens]
          Length = 237

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 23/57 (40%), Positives = 36/57 (63%)

Query: 234 RRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIR 290
           R++R N  K++ +IL ++ Y H  N YPSE+ K  L+ +  ++V Q+ NWF N R R
Sbjct: 19  RKRRGNLPKESVKILRDWLYLHRYNAYPSEQEKLSLSGQTNLSVLQICNWFINARRR 75


>gi|5174681 SIX homeobox 1 [Homo sapiens]
          Length = 284

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 27/61 (44%), Positives = 39/61 (63%), Gaps = 3/61 (4%)

Query: 240 FNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQ 299
           F +++  +L E+ Y+H  NPYPS   K ELA+  G+T +QVSNWF N+R R +    K +
Sbjct: 131 FKEKSRGVLREW-YAH--NPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKER 187

Query: 300 E 300
           E
Sbjct: 188 E 188


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.125    0.352 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,470,044
Number of Sequences: 37866
Number of extensions: 730859
Number of successful extensions: 5621
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 238
Number of HSP's successfully gapped in prelim test: 121
Number of HSP's that attempted gapping in prelim test: 4838
Number of HSP's gapped (non-prelim): 823
length of query: 430
length of database: 18,247,518
effective HSP length: 105
effective length of query: 325
effective length of database: 14,271,588
effective search space: 4638266100
effective search space used: 4638266100
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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