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Search of human proteins with 40807489
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40807489 egf-like module containing, mucin-like, hormone
receptor-like sequence 1 [Homo sapiens]
(886 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40807489 egf-like module containing, mucin-like, hormone rece... 1850 0.0
gi|23397681 egf-like module containing, mucin-like, hormone rece... 486 e-137
gi|23397689 egf-like module containing, mucin-like, hormone rece... 477 e-134
gi|23397683 egf-like module containing, mucin-like, hormone rece... 459 e-129
gi|133930786 egf-like module-containing mucin-like receptor 3 [H... 453 e-127
gi|23397691 egf-like module containing, mucin-like, hormone rece... 450 e-126
gi|17978491 CD97 antigen isoform 1 precursor [Homo sapiens] 437 e-122
gi|23397685 egf-like module containing, mucin-like, hormone rece... 431 e-120
gi|23397693 egf-like module containing, mucin-like, hormone rece... 422 e-118
gi|68508955 CD97 antigen isoform 3 precursor [Homo sapiens] 412 e-115
gi|23397687 egf-like module containing, mucin-like, hormone rece... 387 e-107
gi|17978489 CD97 antigen isoform 2 precursor [Homo sapiens] 380 e-105
gi|148806925 EGF, latrophilin and seven transmembrane domain con... 291 2e-78
gi|163792198 latrophilin 3 precursor [Homo sapiens] 262 9e-70
gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens] 254 2e-67
gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens] 254 2e-67
gi|6912464 latrophilin 2 precursor [Homo sapiens] 251 2e-66
gi|45433552 G protein-coupled receptor 133 [Homo sapiens] 203 7e-52
gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo s... 189 1e-47
gi|110347437 latent transforming growth factor beta binding prot... 188 2e-47
gi|110347412 latent transforming growth factor beta binding prot... 188 2e-47
gi|110347431 latent transforming growth factor beta binding prot... 188 2e-47
gi|194328809 latent transforming growth factor beta binding prot... 174 2e-43
gi|18497288 latent transforming growth factor beta binding prote... 174 2e-43
gi|4557733 latent transforming growth factor beta binding protei... 173 6e-43
gi|56237021 fibrillin 3 precursor [Homo sapiens] 171 2e-42
gi|24430141 fibrillin 1 precursor [Homo sapiens] 171 4e-42
gi|66346695 fibrillin 2 precursor [Homo sapiens] 171 4e-42
gi|46249414 latent transforming growth factor beta binding prote... 170 6e-42
gi|46249412 latent transforming growth factor beta binding prote... 170 6e-42
>gi|40807489 egf-like module containing, mucin-like, hormone
receptor-like sequence 1 [Homo sapiens]
Length = 886
Score = 1850 bits (4793), Expect = 0.0
Identities = 886/886 (100%), Positives = 886/886 (100%)
Query: 1 MRGFNLLLFWGCCVMHSWEGHIRPTRKPNTKGNNCRDSTLCPAYATCTNTVDSYYCACKQ 60
MRGFNLLLFWGCCVMHSWEGHIRPTRKPNTKGNNCRDSTLCPAYATCTNTVDSYYCACKQ
Sbjct: 1 MRGFNLLLFWGCCVMHSWEGHIRPTRKPNTKGNNCRDSTLCPAYATCTNTVDSYYCACKQ 60
Query: 61 GFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDW 120
GFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDW
Sbjct: 61 GFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDW 120
Query: 121 VPGKPGNFSCTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGFISRNSTCEDVDECADPR 180
VPGKPGNFSCTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGFISRNSTCEDVDECADPR
Sbjct: 121 VPGKPGNFSCTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGFISRNSTCEDVDECADPR 180
Query: 181 ACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTEMCPINSTCTNTPG 240
ACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTEMCPINSTCTNTPG
Sbjct: 181 ACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTEMCPINSTCTNTPG 240
Query: 241 SYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGF 300
SYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGF
Sbjct: 241 SYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGF 300
Query: 301 HPNPEGSQKDGNFSCQRVLFKCKEDVIPDNKQIQQCQEGTAVKPAYVSFCAQINNIFSVL 360
HPNPEGSQKDGNFSCQRVLFKCKEDVIPDNKQIQQCQEGTAVKPAYVSFCAQINNIFSVL
Sbjct: 301 HPNPEGSQKDGNFSCQRVLFKCKEDVIPDNKQIQQCQEGTAVKPAYVSFCAQINNIFSVL 360
Query: 361 DKVCENKTTVVSLKNTTESFVPVLKQISTWTKFTKEETSSLATVFLESVESMTLASFWKP 420
DKVCENKTTVVSLKNTTESFVPVLKQISTWTKFTKEETSSLATVFLESVESMTLASFWKP
Sbjct: 361 DKVCENKTTVVSLKNTTESFVPVLKQISTWTKFTKEETSSLATVFLESVESMTLASFWKP 420
Query: 421 SANITPAVRTEYLDIESKVINKECSEENVTLDLVAKGDKMKIGCSTIEESESTETTGVAF 480
SANITPAVRTEYLDIESKVINKECSEENVTLDLVAKGDKMKIGCSTIEESESTETTGVAF
Sbjct: 421 SANITPAVRTEYLDIESKVINKECSEENVTLDLVAKGDKMKIGCSTIEESESTETTGVAF 480
Query: 481 VSFVGMESVLNERFFKDHQAPLTTSEIKLKMNSRVVGGIMTGEKKDGFSDPIIYTLENIQ 540
VSFVGMESVLNERFFKDHQAPLTTSEIKLKMNSRVVGGIMTGEKKDGFSDPIIYTLENIQ
Sbjct: 481 VSFVGMESVLNERFFKDHQAPLTTSEIKLKMNSRVVGGIMTGEKKDGFSDPIIYTLENIQ 540
Query: 541 PKQKFERPICVSWSTDVKGGRWTSFGCVILEASETYTICSCNQMANLAVIMASGELTMDF 600
PKQKFERPICVSWSTDVKGGRWTSFGCVILEASETYTICSCNQMANLAVIMASGELTMDF
Sbjct: 541 PKQKFERPICVSWSTDVKGGRWTSFGCVILEASETYTICSCNQMANLAVIMASGELTMDF 600
Query: 601 SLYIISHVGIIISLVCLVLAIATFLLCRSIRNHNTYLHLHLCVCLLLAKTLFLAGIHKTD 660
SLYIISHVGIIISLVCLVLAIATFLLCRSIRNHNTYLHLHLCVCLLLAKTLFLAGIHKTD
Sbjct: 601 SLYIISHVGIIISLVCLVLAIATFLLCRSIRNHNTYLHLHLCVCLLLAKTLFLAGIHKTD 660
Query: 661 NKMGCAIIAGFLHYLFLACFFWMLVEAVILFLMVRNLKVVNYFSSRNIKMLHICAFGYGL 720
NKMGCAIIAGFLHYLFLACFFWMLVEAVILFLMVRNLKVVNYFSSRNIKMLHICAFGYGL
Sbjct: 661 NKMGCAIIAGFLHYLFLACFFWMLVEAVILFLMVRNLKVVNYFSSRNIKMLHICAFGYGL 720
Query: 721 PMLVVVISASVQPQGYGMHNRCWLNTETGFIWSFLGPVCTVIVINSLLLTWTLWILRQRL 780
PMLVVVISASVQPQGYGMHNRCWLNTETGFIWSFLGPVCTVIVINSLLLTWTLWILRQRL
Sbjct: 721 PMLVVVISASVQPQGYGMHNRCWLNTETGFIWSFLGPVCTVIVINSLLLTWTLWILRQRL 780
Query: 781 SSVNAEVSTLKDTRLLTFKAFAQLFILGCSWVLGIFQIGPVAGVMAYLFTIINSLQGAFI 840
SSVNAEVSTLKDTRLLTFKAFAQLFILGCSWVLGIFQIGPVAGVMAYLFTIINSLQGAFI
Sbjct: 781 SSVNAEVSTLKDTRLLTFKAFAQLFILGCSWVLGIFQIGPVAGVMAYLFTIINSLQGAFI 840
Query: 841 FLIHCLLNGQVREEYKRWITGKTKPSSQSQTSRILLSSMPSASKTG 886
FLIHCLLNGQVREEYKRWITGKTKPSSQSQTSRILLSSMPSASKTG
Sbjct: 841 FLIHCLLNGQVREEYKRWITGKTKPSSQSQTSRILLSSMPSASKTG 886
>gi|23397681 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform a [Homo sapiens]
Length = 823
Score = 486 bits (1251), Expect = e-137
Identities = 313/853 (36%), Positives = 442/853 (51%), Gaps = 95/853 (11%)
Query: 74 PGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDI 133
PG +D C++ C +SSC N + C C GFSS + P + +C DI
Sbjct: 19 PGAETQDSRGCARW---CPQDSSCVNATA---CRCNPGFSSFSEIITTPME----TCDDI 68
Query: 134 NECLTSSV--CPEHSDCVNSMGSYSCSCQVGFI----------SRNSTCEDVDECA-DPR 180
NEC T S C + SDC N+ GSY C C G+ +TC+DVDEC +PR
Sbjct: 69 NECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPR 128
Query: 181 ACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTE---MCPINSTCTN 237
C + TC NT+G+Y+C C PGF+ C D++ECT C ++ C N
Sbjct: 129 LCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKL------CTDVNECTSGQNPCHSSTHCLN 182
Query: 238 TPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCI 297
GSY C C PG+ P G N + V C D+DEC C +++C N +GSYSC C
Sbjct: 183 NVGSYQCRCRPGWQPIPGSPNGPNNTV-CEDVDECSSGQHQCDSSTVCFNTVGSYSCRCR 241
Query: 298 AGFHPNPEGSQKDGNFSCQRVLFKCKEDVIPDNKQ-----IQQCQE-GTAVKPAYVSFCA 351
G+ P + C+ + F + Q + Q+ G KP +
Sbjct: 242 PGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDYKPGLAN--N 299
Query: 352 QINNIFSVLDKVCENKTTVVSLKNTTESFVPVLKQISTWTKFTKEETSSLATVFLESVES 411
I +I LD++ E + +L P L+Q +A+ L+ +E
Sbjct: 300 TIQSILQALDELLEAPGDLETL--------PRLQQ------------HCVASHLLDGLED 339
Query: 412 MTLASFWKPSAN-----ITPAVRTEYLDIESKVINKECSEENVTLDLVAKGDKMKIGCST 466
+ L K +N PA L+++ +V +N + M++ +
Sbjct: 340 V-LRGLSKNLSNGLLNFSYPAGTELSLEVQKQVDRSVTLRQNQAV--------MQLDWNQ 390
Query: 467 IEESESTETTGVAFVSFVGMESVLNER-----------FFKDHQAPLTTSEIKLKMNSRV 515
++S + V VS GM +L E + HQ L L S V
Sbjct: 391 AQKSGDPGPSVVGLVSIPGMGKLLAEAPLVLEPEKQMLLHETHQGLLQDGSPILL--SDV 448
Query: 516 VGGIMTGEKKDGFSDPIIYTLEN--IQPKQKFERPICVSWSTDVKG-GRWTSFGCVILEA 572
+ ++ S P+ +T + + P+QK +CV W G G W + GC +
Sbjct: 449 ISAFLSNNDTQNLSSPVTFTFSHRSVIPRQKV---LCVFWEHGQNGCGHWATTGCSTIGT 505
Query: 573 SETYTICSCNQMANLAVIMASGELTM-DFSLYIISHVGIIISLVCLVLAIATFLLCRSIR 631
+T TIC C +++ AV+MA ++ D L +I+++G+ +SL+CL+LA TFLLC++I+
Sbjct: 506 RDTSTICRCTHLSSFAVLMAHYDVQEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQ 565
Query: 632 NHNTYLHLHLCVCLLLAKTLFLAGIHKTDNKMGCAIIAGFLHYLFLACFFWMLVEAVILF 691
N +T LHL L +CL LA LFL I +T +K+ C+IIAG LHYL+LA WML+EA+ LF
Sbjct: 566 NTSTSLHLQLSLCLFLAHLLFLVAIDQTGHKVLCSIIAGTLHYLYLATLTWMLLEALYLF 625
Query: 692 LMVRNLKVVNYFSSRNIKMLHICAFGYGLPMLVVVISASVQPQGYGMHNRCWLNTETGFI 751
L RNL VVNY S + GYG+P + V ISA+ +P YG +RCWL E GFI
Sbjct: 626 LTARNLTVVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFI 685
Query: 752 WSFLGPVCTVIVINSLLLTWTLWILRQRLSSVNAEVSTLKDTRLLTFKAFAQLFILGCSW 811
W FLGPVC + +N +L TLWIL+ RLSS+N+EVSTL++TR+L FKA AQLFILGC+W
Sbjct: 686 WGFLGPVCAIFSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTW 745
Query: 812 VLGIFQIGPVAGVMAYLFTIINSLQGAFIFLIHCLLNGQVREEYKRWITGKTKPSSQSQT 871
LGI Q+GP A VMAYLFTIINSLQG FIFL++CLL+ QVRE+Y +W G K ++S+
Sbjct: 746 CLGILQVGPAARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWSKGIRKLKTESEM 805
Query: 872 SRILLSSMPSASK 884
+ S+ SK
Sbjct: 806 HTLSSSAKADTSK 818
Score = 130 bits (326), Expect = 7e-30
Identities = 75/194 (38%), Positives = 98/194 (50%), Gaps = 22/194 (11%)
Query: 41 CPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVR-CKDIDECSQSPQPCGPNSSCKN 99
C ++ C NT SY C C G+ +G FK+ C+D+DEC Q+P+ C +C N
Sbjct: 79 CGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVN 138
Query: 100 LSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSD--CVNSMGSYSC 157
G Y C CL GF P P CTD+NEC TS P HS C+N++GSY C
Sbjct: 139 TLGSYTCQCLPGFKLK------PEDPK--LCTDVNEC-TSGQNPCHSSTHCLNNVGSYQC 189
Query: 158 SCQVGFI--------SRNSTCEDVDECAD-PRACPEHATCNNTVGNYSCFCNPGFESSSG 208
C+ G+ N+ CEDVDEC+ C C NTVG+YSC C PG++ G
Sbjct: 190 RCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHG 249
Query: 209 HLSFQGLKASCEDI 222
+ Q CED+
Sbjct: 250 IPNNQ-KDTVCEDM 262
Score = 97.4 bits (241), Expect = 5e-20
Identities = 54/161 (33%), Positives = 78/161 (48%), Gaps = 25/161 (15%)
Query: 29 NTKGNNCRD-------STLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDI 81
N N C+D LC +Y TC NT+ SY C C GF +DP + C D+
Sbjct: 111 NESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKP-----EDPKL-CTDV 164
Query: 82 DECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSS- 140
+EC+ PC ++ C N G Y+C C G+ G+ P P N C D++EC +
Sbjct: 165 NECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGS---PNGPNNTVCEDVDECSSGQH 221
Query: 141 VCPEHSDCVNSMGSYSCSCQVGFISR--------NSTCEDV 173
C + C N++GSYSC C+ G+ R ++ CED+
Sbjct: 222 QCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDM 262
>gi|23397689 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform e [Homo sapiens]
Length = 812
Score = 477 bits (1227), Expect = e-134
Identities = 300/840 (35%), Positives = 432/840 (51%), Gaps = 80/840 (9%)
Query: 74 PGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDI 133
PG +D C++ C +SSC N + C C GFSS + P + +C DI
Sbjct: 19 PGAETQDSRGCARW---CPQDSSCVNATA---CRCNPGFSSFSEIITTPME----TCDDI 68
Query: 134 NECLTSSV--CPEHSDCVNSMGSYSCSCQVGFI----------SRNSTCEDVDECA-DPR 180
NEC T S C + SDC N+ GSY C C G+ +TC+DVDEC +PR
Sbjct: 69 NECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPR 128
Query: 181 ACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTE---MCPINSTCTN 237
C + TC NT+G+Y+C C PGF+ C D++ECT C ++ C N
Sbjct: 129 LCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKL------CTDVNECTSGQNPCHSSTHCLN 182
Query: 238 TPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCI 297
GSY C C PG+ P G N + V C D+DEC C +++C N +GSYSC C
Sbjct: 183 NVGSYQCRCRPGWQPIPGSPNGPNNTV-CEDVDECSSGQHQCDSSTVCFNTVGSYSCRC- 240
Query: 298 AGFHPNPEGSQKDGNFSCQRVLFKCKEDVIPDNKQIQQCQEGT--AVKPAYVSFCAQINN 355
P + G IP+N++ C++ T P ++
Sbjct: 241 -----RPGWKPRHG---------------IPNNQKDTVCEDMTFSTWTPPPGVHSQTLSR 280
Query: 356 IFSVLDKVCEN------KTTVVSLKNTTESFVPVLKQISTWTKFTKEETSSLATVFLESV 409
F + + + T+ S+ + + + T + + +S LE V
Sbjct: 281 FFDKVQDLGRDYKPGLANNTIQSILQALDELLEAPGDLETLPRLQQHCVASHLLDGLEDV 340
Query: 410 ESMTLASFWKPSANITPAVRTEY-LDIESKVINKECSEENVTLDLVAKGDKMKIGCSTIE 468
+ N + TE L+++ +V +N + M++ + +
Sbjct: 341 LRGLSKNLSNGLLNFSYPAGTELSLEVQKQVDRSVTLRQNQAV--------MQLDWNQAQ 392
Query: 469 ESESTETTGVAFVSFVGMESVLNERFFKDHQAPLTTSEIKLKMNSRVVGGIMTGEKKDGF 528
+S + + + +E + HQ L L S V+ ++
Sbjct: 393 KSGDPGMGKLLAEAPLVLEPEKQMLLHETHQGLLQDGSPILL--SDVISAFLSNNDTQNL 450
Query: 529 SDPIIYTLEN--IQPKQKFERPICVSWSTDVKG-GRWTSFGCVILEASETYTICSCNQMA 585
S P+ +T + + P+QK +CV W G G W + GC + +T TIC C ++
Sbjct: 451 SSPVTFTFSHRSVIPRQKV---LCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTHLS 507
Query: 586 NLAVIMASGELTM-DFSLYIISHVGIIISLVCLVLAIATFLLCRSIRNHNTYLHLHLCVC 644
+ AV+MA ++ D L +I+++G+ +SL+CL+LA TFLLC++I+N +T LHL L +C
Sbjct: 508 SFAVLMAHYDVQEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLC 567
Query: 645 LLLAKTLFLAGIHKTDNKMGCAIIAGFLHYLFLACFFWMLVEAVILFLMVRNLKVVNYFS 704
L LA LFL I +T +K+ C+IIAG LHYL+LA WML+EA+ LFL RNL VVNY S
Sbjct: 568 LFLAHLLFLVAIDQTGHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSS 627
Query: 705 SRNIKMLHICAFGYGLPMLVVVISASVQPQGYGMHNRCWLNTETGFIWSFLGPVCTVIVI 764
+ GYG+P + V ISA+ +P YG +RCWL E GFIW FLGPVC + +
Sbjct: 628 INRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVCAIFSV 687
Query: 765 NSLLLTWTLWILRQRLSSVNAEVSTLKDTRLLTFKAFAQLFILGCSWVLGIFQIGPVAGV 824
N +L TLWIL+ RLSS+N+EVSTL++TR+L FKA AQLFILGC+W LGI Q+GP A V
Sbjct: 688 NLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQVGPAARV 747
Query: 825 MAYLFTIINSLQGAFIFLIHCLLNGQVREEYKRWITGKTKPSSQSQTSRILLSSMPSASK 884
MAYLFTIINSLQG FIFL++CLL+ QVRE+Y +W G K ++S+ + S+ SK
Sbjct: 748 MAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWSKGIRKLKTESEMHTLSSSAKADTSK 807
Score = 130 bits (326), Expect = 7e-30
Identities = 75/194 (38%), Positives = 98/194 (50%), Gaps = 22/194 (11%)
Query: 41 CPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVR-CKDIDECSQSPQPCGPNSSCKN 99
C ++ C NT SY C C G+ +G FK+ C+D+DEC Q+P+ C +C N
Sbjct: 79 CGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVN 138
Query: 100 LSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSD--CVNSMGSYSC 157
G Y C CL GF P P CTD+NEC TS P HS C+N++GSY C
Sbjct: 139 TLGSYTCQCLPGFKLK------PEDPK--LCTDVNEC-TSGQNPCHSSTHCLNNVGSYQC 189
Query: 158 SCQVGFI--------SRNSTCEDVDECAD-PRACPEHATCNNTVGNYSCFCNPGFESSSG 208
C+ G+ N+ CEDVDEC+ C C NTVG+YSC C PG++ G
Sbjct: 190 RCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHG 249
Query: 209 HLSFQGLKASCEDI 222
+ Q CED+
Sbjct: 250 IPNNQ-KDTVCEDM 262
Score = 97.4 bits (241), Expect = 5e-20
Identities = 54/161 (33%), Positives = 78/161 (48%), Gaps = 25/161 (15%)
Query: 29 NTKGNNCRD-------STLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDI 81
N N C+D LC +Y TC NT+ SY C C GF +DP + C D+
Sbjct: 111 NESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKP-----EDPKL-CTDV 164
Query: 82 DECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSS- 140
+EC+ PC ++ C N G Y+C C G+ G+ P P N C D++EC +
Sbjct: 165 NECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGS---PNGPNNTVCEDVDECSSGQH 221
Query: 141 VCPEHSDCVNSMGSYSCSCQVGFISR--------NSTCEDV 173
C + C N++GSYSC C+ G+ R ++ CED+
Sbjct: 222 QCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDM 262
>gi|23397683 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform b [Homo sapiens]
Length = 774
Score = 459 bits (1181), Expect = e-129
Identities = 289/784 (36%), Positives = 416/784 (53%), Gaps = 88/784 (11%)
Query: 142 CPEHSDCVNSMGSYSCSCQVGFISRNS-------TCEDVDECA--DPRACPEHATCNNTV 192
CP+ S CVN+ +C C GF S + TC+D++ECA +C + + C NT
Sbjct: 33 CPQDSSCVNAT---ACRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTE 89
Query: 193 GNYSCFCNPGFESSSGHLSFQG-LKASCEDIDECTE---MCPINSTCTNTPGSYFCTCHP 248
G+Y C C+PG+E SG +F+ + +C+D+DEC + +C TC NT GSY C C P
Sbjct: 90 GSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLP 149
Query: 249 GFA--PSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEG 306
GF P + +L C D+DEC C +++C N +GSYSC C G+ P
Sbjct: 150 GFKLKPEDPKL--------CTDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGI 201
Query: 307 SQKDGNFSCQRVLFKCKEDVIPDNKQ-----IQQCQE-GTAVKPAYVSFCAQINNIFSVL 360
+ C+ + F + Q + Q+ G KP + I +I L
Sbjct: 202 PNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDYKPGLAN--NTIQSILQAL 259
Query: 361 DKVCENKTTVVSLKNTTESFVPVLKQISTWTKFTKEETSSLATVFLESVESMTLASFWKP 420
D++ E + +L P L+Q +A+ L+ +E + L K
Sbjct: 260 DELLEAPGDLETL--------PRLQQ------------HCVASHLLDGLEDV-LRGLSKN 298
Query: 421 SAN-----ITPAVRTEYLDIESKVINKECSEENVTLDLVAKGDKMKIGCSTIEESESTET 475
+N PA L+++ +V +N + M++ + ++S
Sbjct: 299 LSNGLLNFSYPAGTELSLEVQKQVDRSVTLRQNQAV--------MQLDWNQAQKSGDPGP 350
Query: 476 TGVAFVSFVGMESVLNER-----------FFKDHQAPLTTSEIKLKMNSRVVGGIMTGEK 524
+ V VS GM +L E + HQ L L S V+ ++
Sbjct: 351 SVVGLVSIPGMGKLLAEAPLVLEPEKQMLLHETHQGLLQDGSPILL--SDVISAFLSNND 408
Query: 525 KDGFSDPIIYTLEN--IQPKQKFERPICVSWSTDVKG-GRWTSFGCVILEASETYTICSC 581
S P+ +T + + P+QK +CV W G G W + GC + +T TIC C
Sbjct: 409 TQNLSSPVTFTFSHRSVIPRQKV---LCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRC 465
Query: 582 NQMANLAVIMASGELTM-DFSLYIISHVGIIISLVCLVLAIATFLLCRSIRNHNTYLHLH 640
+++ AV+MA ++ D L +I+++G+ +SL+CL+LA TFLLC++I+N +T LHL
Sbjct: 466 THLSSFAVLMAHYDVQEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQ 525
Query: 641 LCVCLLLAKTLFLAGIHKTDNKMGCAIIAGFLHYLFLACFFWMLVEAVILFLMVRNLKVV 700
L +CL LA LFL I +T +K+ C+IIAG LHYL+LA WML+EA+ LFL RNL VV
Sbjct: 526 LSLCLFLAHLLFLVAIDQTGHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVV 585
Query: 701 NYFSSRNIKMLHICAFGYGLPMLVVVISASVQPQGYGMHNRCWLNTETGFIWSFLGPVCT 760
NY S + GYG+P + V ISA+ +P YG +RCWL E GFIW FLGPVC
Sbjct: 586 NYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVCA 645
Query: 761 VIVINSLLLTWTLWILRQRLSSVNAEVSTLKDTRLLTFKAFAQLFILGCSWVLGIFQIGP 820
+ +N +L TLWIL+ RLSS+N+EVSTL++TR+L FKA AQLFILGC+W LGI Q+GP
Sbjct: 646 IFSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQVGP 705
Query: 821 VAGVMAYLFTIINSLQGAFIFLIHCLLNGQVREEYKRWITGKTKPSSQSQTSRILLSSMP 880
A VMAYLFTIINSLQG FIFL++CLL+ QVRE+Y +W G K ++S+ + S+
Sbjct: 706 AARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWSKGIRKLKTESEMHTLSSSAKA 765
Query: 881 SASK 884
SK
Sbjct: 766 DTSK 769
Score = 124 bits (312), Expect = 3e-28
Identities = 77/212 (36%), Positives = 104/212 (49%), Gaps = 33/212 (15%)
Query: 74 PGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDI 133
PG +D C++ C +SSC N + C C GFSS + P + +C DI
Sbjct: 19 PGAETQDSRGCARW---CPQDSSCVNATA---CRCNPGFSSFSEIITTPME----TCDDI 68
Query: 134 NECLTSSV--CPEHSDCVNSMGSYSCSCQVGF----------ISRNSTCEDVDEC-ADPR 180
NEC T S C + SDC N+ GSY C C G+ +TC+DVDEC +PR
Sbjct: 69 NECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPR 128
Query: 181 ACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECT---EMCPINSTCTN 237
C + TC NT+G+Y+C C PGF+ C D+DEC+ C ++ C N
Sbjct: 129 LCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKL------CTDVDECSSGQHQCDSSTVCFN 182
Query: 238 TPGSYFCTCHPGFAPSNGQLNFTDQGVECRDI 269
T GSY C C PG+ P +G N + C D+
Sbjct: 183 TVGSYSCRCRPGWKPRHGIPN-NQKDTVCEDM 213
Score = 92.8 bits (229), Expect = 1e-18
Identities = 50/143 (34%), Positives = 71/143 (49%), Gaps = 18/143 (12%)
Query: 41 CPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVR-CKDIDECSQSPQPCGPNSSCKN 99
C ++ C NT SY C C G+ +G FK+ C+D+DEC Q+P+ C +C N
Sbjct: 79 CGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVN 138
Query: 100 LSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSS-VCPEHSDCVNSMGSYSCS 158
G Y C CL GF P P CTD++EC + C + C N++GSYSC
Sbjct: 139 TLGSYTCQCLPGFKLK------PEDPK--LCTDVDECSSGQHQCDSSTVCFNTVGSYSCR 190
Query: 159 CQVGFISR--------NSTCEDV 173
C+ G+ R ++ CED+
Sbjct: 191 CRPGWKPRHGIPNNQKDTVCEDM 213
Score = 65.5 bits (158), Expect = 2e-10
Identities = 37/112 (33%), Positives = 49/112 (43%), Gaps = 16/112 (14%)
Query: 29 NTKGNNCRD-------STLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDI 81
N N C+D LC +Y TC NT+ SY C C GF +DP + C D+
Sbjct: 111 NESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKP-----EDPKL-CTDV 164
Query: 82 DECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDI 133
DECS C ++ C N G Y C C G+ G +P + C D+
Sbjct: 165 DECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHG---IPNNQKDTVCEDM 213
>gi|133930786 egf-like module-containing mucin-like receptor 3 [Homo
sapiens]
Length = 652
Score = 453 bits (1165), Expect = e-127
Identities = 244/644 (37%), Positives = 370/644 (57%), Gaps = 50/644 (7%)
Query: 229 CPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPST-CGPNSICTN 287
CP N++C N CTC+ G+ +GQ FT C DI+EC S CG N++C N
Sbjct: 31 CPPNASCVNNT---HCTCNHGYTSGSGQKLFTFPLETCNDINECTPPYSVYCGFNAVCYN 87
Query: 288 ALGSYSCGCIAGFHPNPEGSQKDGNFSCQRVLFKCKEDVIPDNKQIQQCQEGTAVKPAYV 347
GS+ C C+ G+ + Q FS N CQ+ T+
Sbjct: 88 VEGSFYCQCVPGYRLHSGNEQ----FS---------------NSNENTCQDTTS------ 122
Query: 348 SFCAQINNIFSVLDKVCENKTTVVSLKNTTESFVPVLKQISTWTKFTKEETSSLATVFLE 407
K E + L+ + F +L + W ++E SS AT L
Sbjct: 123 -------------SKTTEGRK---ELQKIVDKFESLLTNQTLWRTEGRQEISSTATTILR 166
Query: 408 SVESMTLASFWKPSANITPAVRTEYLDIESKVINKECSEENVTLDLVAKGDKMKIGCSTI 467
VES L + K ++ + + IE++ I CSEE T +L + + M I CS I
Sbjct: 167 DVESKVLETALKDPEQKVLKIQNDSVAIETQAITDNCSEERKTFNLNVQMNSMDIRCSDI 226
Query: 468 EESESTETTGVAFVSFVGMESVLNERFFKDHQAPLTTSEIKLKMNSRVVGGIMTGEKKDG 527
+ ++ + +AF+S+ + +++N FF++ + ++ +NS+VV + ++
Sbjct: 227 IQGDTQGPSAIAFISYSSLGNIINATFFEEMD-----KKDQVYLNSQVVSAAIGPKRNVS 281
Query: 528 FSDPIIYTLENIQPKQKFERPICVSWSTDVKGGRWTSFGCVILEASETYTICSCNQMANL 587
S + T ++++ ++ CV W + +G +W+ GC ++ ++++T+C+C+ +++
Sbjct: 282 LSKSVTLTFQHVKMTPSTKKVFCVYWKSTGQGSQWSRDGCFLIHVNKSHTMCNCSHLSSF 341
Query: 588 AVIMASGELTMDFSLYIISHVGIIISLVCLVLAIATFLLCRSIRNHNTYLHLHLCVCLLL 647
AV+MA D L +I++VG+ +SL+CL+LA TFLLC++IRN +T LHL L +CL L
Sbjct: 342 AVLMALTSQEEDPVLTVITYVGLSVSLLCLLLAALTFLLCKAIRNTSTSLHLQLSLCLFL 401
Query: 648 AKTLFLAGIHKTDNKMGCAIIAGFLHYLFLACFFWMLVEAVILFLMVRNLKVVNYFSSRN 707
A LFL GI +T+ K+ C+IIAG LHYL+LA F WML+E V LFL RNL VVNY S
Sbjct: 402 AHLLFLVGIDRTEPKVLCSIIAGALHYLYLAAFTWMLLEGVHLFLTARNLTVVNYSSINR 461
Query: 708 IKMLHICAFGYGLPMLVVVISASVQPQGYGMHNRCWLNTETGFIWSFLGPVCTVIVINSL 767
+ + GYG+P + V ISA+ P YG +RCWL+ + GF+WSFLGPVC + N +
Sbjct: 462 LMKWIMFPVGYGVPAVTVAISAASWPHLYGTADRCWLHLDQGFMWSFLGPVCAIFSANLV 521
Query: 768 LLTWTLWILRQRLSSVNAEVSTLKDTRLLTFKAFAQLFILGCSWVLGIFQIGPVAGVMAY 827
L WIL+++LSS+N+EVST+++TR+L FKA AQLFILGC+W LG+ Q+GP A VMAY
Sbjct: 522 LFILVFWILKRKLSSLNSEVSTIQNTRMLAFKATAQLFILGCTWCLGLLQVGPAAQVMAY 581
Query: 828 LFTIINSLQGAFIFLIHCLLNGQVREEYKRWITGKTKPSSQSQT 871
LFTIINSLQG FIFL++CLL+ QV+++Y++W K S+S+T
Sbjct: 582 LFTIINSLQGFFIFLVYCLLSQQVQKQYQKWFREIVKSKSESET 625
Score = 66.6 bits (161), Expect = 1e-10
Identities = 34/92 (36%), Positives = 47/92 (51%), Gaps = 8/92 (8%)
Query: 182 CPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTE----MCPINSTCTN 237
CP +A+C V N C CN G+ S SG F +C DI+ECT C N+ C N
Sbjct: 31 CPPNASC---VNNTHCTCNHGYTSGSGQKLFTFPLETCNDINECTPPYSVYCGFNAVCYN 87
Query: 238 TPGSYFCTCHPGFAPSNGQLNFTDQGVE-CRD 268
GS++C C PG+ +G F++ C+D
Sbjct: 88 VEGSFYCQCVPGYRLHSGNEQFSNSNENTCQD 119
Score = 65.5 bits (158), Expect = 2e-10
Identities = 42/134 (31%), Positives = 60/134 (44%), Gaps = 13/134 (9%)
Query: 7 LLFWGCCVMHSWEGHIRPTRKPNTKGNNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSN 66
LL G C + S G + T+K T CP A+C N +C C G+ S +
Sbjct: 5 LLLPGLCFLLSLFGAV--TQKTKTS------CAKCPPNASCVNNT---HCTCNHGYTSGS 53
Query: 67 GQNHFKDPGVRCKDIDECSQSPQP-CGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKP 125
GQ F P C DI+EC+ CG N+ C N+ G + C C+ G+ +GN+
Sbjct: 54 GQKLFTFPLETCNDINECTPPYSVYCGFNAVCYNVEGSFYCQCVPGYRLHSGNEQFSNSN 113
Query: 126 GNFSCTDINECLTS 139
N +C D T+
Sbjct: 114 EN-TCQDTTSSKTT 126
Score = 53.9 bits (128), Expect = 6e-07
Identities = 29/92 (31%), Positives = 46/92 (50%), Gaps = 15/92 (16%)
Query: 142 CPEHSDCVNSMGSYSCSCQVGFISRNS---------TCEDVDECADPRA--CPEHATCNN 190
CP ++ CVN+ C+C G+ S + TC D++EC P + C +A C N
Sbjct: 31 CPPNASCVNNT---HCTCNHGYTSGSGQKLFTFPLETCNDINECTPPYSVYCGFNAVCYN 87
Query: 191 TVGNYSCFCNPGFESSSGHLSFQGL-KASCED 221
G++ C C PG+ SG+ F + +C+D
Sbjct: 88 VEGSFYCQCVPGYRLHSGNEQFSNSNENTCQD 119
Score = 45.4 bits (106), Expect = 2e-04
Identities = 32/97 (32%), Positives = 45/97 (46%), Gaps = 23/97 (23%)
Query: 91 CGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNF---SCTDINECLT--SSVCPEH 145
C PN+SC N + C+C G++S +G K F +C DINEC S C +
Sbjct: 31 CPPNASCVNNT---HCTCNHGYTSGSGQ-----KLFTFPLETCNDINECTPPYSVYCGFN 82
Query: 146 SDCVNSMGSYSCSCQVGF----------ISRNSTCED 172
+ C N GS+ C C G+ S +TC+D
Sbjct: 83 AVCYNVEGSFYCQCVPGYRLHSGNEQFSNSNENTCQD 119
>gi|23397691 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform f [Homo sapiens]
Length = 763
Score = 450 bits (1157), Expect = e-126
Identities = 276/771 (35%), Positives = 406/771 (52%), Gaps = 73/771 (9%)
Query: 142 CPEHSDCVNSMGSYSCSCQVGFISRNS-------TCEDVDECA--DPRACPEHATCNNTV 192
CP+ S CVN+ +C C GF S + TC+D++ECA +C + + C NT
Sbjct: 33 CPQDSSCVNAT---ACRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTE 89
Query: 193 GNYSCFCNPGFESSSGHLSFQG-LKASCEDIDECTE---MCPINSTCTNTPGSYFCTCHP 248
G+Y C C+PG+E SG +F+ + +C+D+DEC + +C TC NT GSY C C P
Sbjct: 90 GSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLP 149
Query: 249 GFA--PSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEG 306
GF P + +L C D+DEC C +++C N +GSYSC C P
Sbjct: 150 GFKLKPEDPKL--------CTDVDECSSGQHQCDSSTVCFNTVGSYSCRC------RPGW 195
Query: 307 SQKDGNFSCQRVLFKCKEDVIPDNKQIQQCQEGT--AVKPAYVSFCAQINNIFSVLDKVC 364
+ G IP+N++ C++ T P ++ F + +
Sbjct: 196 KPRHG---------------IPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLG 240
Query: 365 EN------KTTVVSLKNTTESFVPVLKQISTWTKFTKEETSSLATVFLESVESMTLASFW 418
+ T+ S+ + + + T + + +S LE V +
Sbjct: 241 RDYKPGLANNTIQSILQALDELLEAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLS 300
Query: 419 KPSANITPAVRTEY-LDIESKVINKECSEENVTLDLVAKGDKMKIGCSTIEESESTETTG 477
N + TE L+++ +V +N + M++ + ++S
Sbjct: 301 NGLLNFSYPAGTELSLEVQKQVDRSVTLRQNQAV--------MQLDWNQAQKSGDPGMGK 352
Query: 478 VAFVSFVGMESVLNERFFKDHQAPLTTSEIKLKMNSRVVGGIMTGEKKDGFSDPIIYTLE 537
+ + + +E + HQ L L S V+ ++ S P+ +T
Sbjct: 353 LLAEAPLVLEPEKQMLLHETHQGLLQDGSPILL--SDVISAFLSNNDTQNLSSPVTFTFS 410
Query: 538 N--IQPKQKFERPICVSWSTDVKG-GRWTSFGCVILEASETYTICSCNQMANLAVIMASG 594
+ + P+QK +CV W G G W + GC + +T TIC C +++ AV+MA
Sbjct: 411 HRSVIPRQKV---LCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTHLSSFAVLMAHY 467
Query: 595 ELTM-DFSLYIISHVGIIISLVCLVLAIATFLLCRSIRNHNTYLHLHLCVCLLLAKTLFL 653
++ D L +I+++G+ +SL+CL+LA TFLLC++I+N +T LHL L +CL LA LFL
Sbjct: 468 DVQEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFLAHLLFL 527
Query: 654 AGIHKTDNKMGCAIIAGFLHYLFLACFFWMLVEAVILFLMVRNLKVVNYFSSRNIKMLHI 713
I +T +K+ C+IIAG LHYL+LA WML+EA+ LFL RNL VVNY S +
Sbjct: 528 VAIDQTGHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLM 587
Query: 714 CAFGYGLPMLVVVISASVQPQGYGMHNRCWLNTETGFIWSFLGPVCTVIVINSLLLTWTL 773
GYG+P + V ISA+ +P YG +RCWL E GFIW FLGPVC + +N +L TL
Sbjct: 588 FPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVCAIFSVNLVLFLVTL 647
Query: 774 WILRQRLSSVNAEVSTLKDTRLLTFKAFAQLFILGCSWVLGIFQIGPVAGVMAYLFTIIN 833
WIL+ RLSS+N+EVSTL++TR+L FKA AQLFILGC+W LGI Q+GP A VMAYLFTIIN
Sbjct: 648 WILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQVGPAARVMAYLFTIIN 707
Query: 834 SLQGAFIFLIHCLLNGQVREEYKRWITGKTKPSSQSQTSRILLSSMPSASK 884
SLQG FIFL++CLL+ QVRE+Y +W G K ++S+ + S+ SK
Sbjct: 708 SLQGVFIFLVYCLLSQQVREQYGKWSKGIRKLKTESEMHTLSSSAKADTSK 758
Score = 124 bits (312), Expect = 3e-28
Identities = 77/212 (36%), Positives = 104/212 (49%), Gaps = 33/212 (15%)
Query: 74 PGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDI 133
PG +D C++ C +SSC N + C C GFSS + P + +C DI
Sbjct: 19 PGAETQDSRGCARW---CPQDSSCVNATA---CRCNPGFSSFSEIITTPME----TCDDI 68
Query: 134 NECLTSSV--CPEHSDCVNSMGSYSCSCQVGF----------ISRNSTCEDVDEC-ADPR 180
NEC T S C + SDC N+ GSY C C G+ +TC+DVDEC +PR
Sbjct: 69 NECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPR 128
Query: 181 ACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECT---EMCPINSTCTN 237
C + TC NT+G+Y+C C PGF+ C D+DEC+ C ++ C N
Sbjct: 129 LCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKL------CTDVDECSSGQHQCDSSTVCFN 182
Query: 238 TPGSYFCTCHPGFAPSNGQLNFTDQGVECRDI 269
T GSY C C PG+ P +G N + C D+
Sbjct: 183 TVGSYSCRCRPGWKPRHGIPN-NQKDTVCEDM 213
Score = 108 bits (270), Expect = 2e-23
Identities = 55/140 (39%), Positives = 78/140 (55%), Gaps = 12/140 (8%)
Query: 171 EDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTEMCP 230
+D CA R CP+ ++C N +C CNPGF S S ++ +C+DI+EC +
Sbjct: 24 QDSRGCA--RWCPQDSSCVNAT---ACRCNPGFSSFSEIITTP--METCDDINECATLSK 76
Query: 231 IN----STCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVE-CRDIDECRQDPSTCGPNSIC 285
++ S C NT GSY C C PG+ P +G F ++ C+D+DEC+Q+P C C
Sbjct: 77 VSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTC 136
Query: 286 TNALGSYSCGCIAGFHPNPE 305
N LGSY+C C+ GF PE
Sbjct: 137 VNTLGSYTCQCLPGFKLKPE 156
Score = 92.8 bits (229), Expect = 1e-18
Identities = 50/143 (34%), Positives = 71/143 (49%), Gaps = 18/143 (12%)
Query: 41 CPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVR-CKDIDECSQSPQPCGPNSSCKN 99
C ++ C NT SY C C G+ +G FK+ C+D+DEC Q+P+ C +C N
Sbjct: 79 CGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVN 138
Query: 100 LSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSS-VCPEHSDCVNSMGSYSCS 158
G Y C CL GF P P CTD++EC + C + C N++GSYSC
Sbjct: 139 TLGSYTCQCLPGFKLK------PEDPK--LCTDVDECSSGQHQCDSSTVCFNTVGSYSCR 190
Query: 159 CQVGFISR--------NSTCEDV 173
C+ G+ R ++ CED+
Sbjct: 191 CRPGWKPRHGIPNNQKDTVCEDM 213
Score = 65.5 bits (158), Expect = 2e-10
Identities = 37/112 (33%), Positives = 49/112 (43%), Gaps = 16/112 (14%)
Query: 29 NTKGNNCRD-------STLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDI 81
N N C+D LC +Y TC NT+ SY C C GF +DP + C D+
Sbjct: 111 NESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKP-----EDPKL-CTDV 164
Query: 82 DECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDI 133
DECS C ++ C N G Y C C G+ G +P + C D+
Sbjct: 165 DECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHG---IPNNQKDTVCEDM 213
>gi|17978491 CD97 antigen isoform 1 precursor [Homo sapiens]
Length = 835
Score = 437 bits (1125), Expect = e-122
Identities = 275/853 (32%), Positives = 425/853 (49%), Gaps = 105/853 (12%)
Query: 74 PGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDI 133
PG +D C++ C NSSC N + C C GFSS + P + +C DI
Sbjct: 16 PGAETQDSRGCARW---CPQNSSCVNATA---CRCNPGFSSFSEIITTPTE----TCDDI 65
Query: 134 NECLTSSV--CPEHSDCVNSMGSYSCSCQVGFI----------SRNSTCEDVDECA-DPR 180
NEC T S C + SDC N+ GSY C C G+ +TC+DVDEC +PR
Sbjct: 66 NECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPR 125
Query: 181 ACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTE---MCPINSTCTN 237
C + TC NT+G+Y+C C PGF+ C D++ECT C ++ C N
Sbjct: 126 LCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKV------CTDVNECTSGQNPCHSSTHCLN 179
Query: 238 TPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCI 297
GSY C C PG+ P G N + V C D+DEC C +++C N +GSYSC C
Sbjct: 180 NVGSYQCRCRPGWQPIPGSPNGPNNTV-CEDVDECSSGQHQCDSSTVCFNTVGSYSCRCR 238
Query: 298 AGFHPNPEGSQKDGNFSCQRVLFKC--------KEDVIPDNKQIQQCQEGTAVKPAYVSF 349
G+ P + C+ + F + + ++Q + A V+
Sbjct: 239 PGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTSSAEVT- 297
Query: 350 CAQINNIFSVLDKVCENKTTVVSLKNTTESFVPVLKQISTWTKFTKEETSSLATVFLESV 409
I N+ ++D++ E V +L PV I+T + S+L +
Sbjct: 298 ---IQNVIKLVDELMEAPGDVEALAP------PVRHLIAT------QLLSNLEDIMRILA 342
Query: 410 ESMTLASFWKPSANITPAVRTEYLDIESKVINKECSEENVTLDLVAKGDKMKIGCSTIEE 469
+S+ F I+P+ + E ++ +E ++NVT+ +MK+ +
Sbjct: 343 KSLPKGPF----TYISPS------NTELTLMIQERGDKNVTMG--QSSARMKLNWAVAAG 390
Query: 470 SESTETTGVAFVSFVGMESVLNERFFKDHQAPLTTSE---------IKLKMNSRVVGGIM 520
+E +S M ++L H E ++L+ S V +
Sbjct: 391 AEDPGPAVAGILSIQNMTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFL 450
Query: 521 TGEKKDGFSDPIIYTLENIQ---------PKQKFERP------ICVSWSTDV-KGGRWTS 564
+ + PI++ +++ P K P +C W +D +GG W +
Sbjct: 451 SHNNTKELNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWAT 510
Query: 565 FGCVILEASETYTICSCNQMANLAVIMASGELTMDFSLYIISHVGIIISLVCLVLAIATF 624
GC +L + T C C+ +++ A++MA ++ D+ L +I+ VG+ +SL CL+L I TF
Sbjct: 511 EGCQVLGSKNGSTTCQCSHLSSFAILMAHYDVE-DWKLTLITRVGLALSLFCLLLCILTF 569
Query: 625 LLCRSIRNHNTYLHLHLCVCLLLAKTLFLAGIHKTDNKMG--CAIIAGFLHYLFLACFFW 682
LL R I+ T +HLHLC+CL + T+FLAGI ++G C ++AG LHY FLA F W
Sbjct: 570 LLVRPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCW 629
Query: 683 MLVEAVILFLMVRNLKVVNYFSSRNIKMLHICAFGYGLPMLVVVISASVQPQGYGMHNRC 742
M +E + L+ +V V F + + +C GYG+P+L+V +SA++ +GYG C
Sbjct: 630 MSLEGLELYFLV-----VRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYC 684
Query: 743 WLNTETGFIWSFLGPVCTVIVINSLLLTWTLWILRQRLSSVNAEVSTLKDTRLLTFKAFA 802
WL+ E GF+WSFLGPV +I+ N+++ T+W L Q+ S +N ++ LK R LT A A
Sbjct: 685 WLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIA 744
Query: 803 QLFILGCSWVLGIFQIGPVAGVMAYLFTIINSLQGAFIFLIHCLLNGQVREEYKRW---I 859
QLF+LGC+WV G+F + V+ Y+FTI+N LQGAF++L+HCLLN +VREEY++W +
Sbjct: 745 QLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWACLV 804
Query: 860 TGKTKPSSQSQTS 872
G +K S + T+
Sbjct: 805 AGGSKYSEFTSTT 817
Score = 132 bits (333), Expect = 1e-30
Identities = 75/194 (38%), Positives = 100/194 (51%), Gaps = 22/194 (11%)
Query: 41 CPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVR-CKDIDECSQSPQPCGPNSSCKN 99
C ++ C NT SY C C G+ +G FK+ C+D+DEC Q+P+ C +C N
Sbjct: 76 CGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVN 135
Query: 100 LSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSD--CVNSMGSYSC 157
G Y C CL GF ++P P CTD+NEC TS P HS C+N++GSY C
Sbjct: 136 TLGSYTCQCLPGFK------FIPEDPK--VCTDVNEC-TSGQNPCHSSTHCLNNVGSYQC 186
Query: 158 SCQVGFI--------SRNSTCEDVDECAD-PRACPEHATCNNTVGNYSCFCNPGFESSSG 208
C+ G+ N+ CEDVDEC+ C C NTVG+YSC C PG++ G
Sbjct: 187 RCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHG 246
Query: 209 HLSFQGLKASCEDI 222
+ Q CED+
Sbjct: 247 IPNNQ-KDTVCEDM 259
Score = 97.8 bits (242), Expect = 4e-20
Identities = 55/161 (34%), Positives = 78/161 (48%), Gaps = 25/161 (15%)
Query: 29 NTKGNNCRD-------STLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDI 81
N N C+D LC +Y TC NT+ SY C C GF +DP V C D+
Sbjct: 108 NESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIP-----EDPKV-CTDV 161
Query: 82 DECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSS- 140
+EC+ PC ++ C N G Y+C C G+ G+ P P N C D++EC +
Sbjct: 162 NECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGS---PNGPNNTVCEDVDECSSGQH 218
Query: 141 VCPEHSDCVNSMGSYSCSCQVGFISR--------NSTCEDV 173
C + C N++GSYSC C+ G+ R ++ CED+
Sbjct: 219 QCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDM 259
>gi|23397685 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform c [Homo sapiens]
Length = 730
Score = 431 bits (1109), Expect = e-120
Identities = 273/745 (36%), Positives = 395/745 (53%), Gaps = 74/745 (9%)
Query: 171 EDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTEMCP 230
+D CA R CP+ ++C N +C CNPGF S S ++ +C+DI+EC +
Sbjct: 24 QDSRGCA--RWCPQDSSCVNAT---ACRCNPGFSSFSEIITTP--METCDDINECATLSK 76
Query: 231 IN----STCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVE-CRDIDECRQDPSTCGPNSIC 285
++ S C NT GSY C C PG+ P +G F ++ C+D+DEC C +++C
Sbjct: 77 VSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECSSGQHQCDSSTVC 136
Query: 286 TNALGSYSCGCIAGFHPNPEGSQKDGNFSCQRVLFKCKEDVIPDNKQ-----IQQCQE-G 339
N +GSYSC C G+ P + C+ + F + Q + Q+ G
Sbjct: 137 FNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLG 196
Query: 340 TAVKPAYVSFCAQINNIFSVLDKVCENKTTVVSLKNTTESFVPVLKQISTWTKFTKEETS 399
KP + I +I LD++ E + +L P L+Q
Sbjct: 197 RDYKPGLAN--NTIQSILQALDELLEAPGDLETL--------PRLQQ------------H 234
Query: 400 SLATVFLESVESMTLASFWKPSAN-----ITPAVRTEYLDIESKVINKECSEENVTLDLV 454
+A+ L+ +E + L K +N PA L+++ +V +N +
Sbjct: 235 CVASHLLDGLEDV-LRGLSKNLSNGLLNFSYPAGTELSLEVQKQVDRSVTLRQNQAV--- 290
Query: 455 AKGDKMKIGCSTIEESESTETTGVAFVSFVGMESVLNER-----------FFKDHQAPLT 503
M++ + ++S + V VS GM +L E + HQ L
Sbjct: 291 -----MQLDWNQAQKSGDPGPSVVGLVSIPGMGKLLAEAPLVLEPEKQMLLHETHQGLLQ 345
Query: 504 TSEIKLKMNSRVVGGIMTGEKKDGFSDPIIYTLEN--IQPKQKFERPICVSWSTDVKG-G 560
L S V+ ++ S P+ +T + + P+QK +CV W G G
Sbjct: 346 DGSPILL--SDVISAFLSNNDTQNLSSPVTFTFSHRSVIPRQKV---LCVFWEHGQNGCG 400
Query: 561 RWTSFGCVILEASETYTICSCNQMANLAVIMASGELTM-DFSLYIISHVGIIISLVCLVL 619
W + GC + +T TIC C +++ AV+MA ++ D L +I+++G+ +SL+CL+L
Sbjct: 401 HWATTGCSTIGTRDTSTICRCTHLSSFAVLMAHYDVQEEDPVLTVITYMGLSVSLLCLLL 460
Query: 620 AIATFLLCRSIRNHNTYLHLHLCVCLLLAKTLFLAGIHKTDNKMGCAIIAGFLHYLFLAC 679
A TFLLC++I+N +T LHL L +CL LA LFL I +T +K+ C+IIAG LHYL+LA
Sbjct: 461 AALTFLLCKAIQNTSTSLHLQLSLCLFLAHLLFLVAIDQTGHKVLCSIIAGTLHYLYLAT 520
Query: 680 FFWMLVEAVILFLMVRNLKVVNYFSSRNIKMLHICAFGYGLPMLVVVISASVQPQGYGMH 739
WML+EA+ LFL RNL VVNY S + GYG+P + V ISA+ +P YG
Sbjct: 521 LTWMLLEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTP 580
Query: 740 NRCWLNTETGFIWSFLGPVCTVIVINSLLLTWTLWILRQRLSSVNAEVSTLKDTRLLTFK 799
+RCWL E GFIW FLGPVC + +N +L TLWIL+ RLSS+N+EVSTL++TR+L FK
Sbjct: 581 SRCWLQPEKGFIWGFLGPVCAIFSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFK 640
Query: 800 AFAQLFILGCSWVLGIFQIGPVAGVMAYLFTIINSLQGAFIFLIHCLLNGQVREEYKRWI 859
A AQLFILGC+W LGI Q+GP A VMAYLFTIINSLQG FIFL++CLL+ QVRE+Y +W
Sbjct: 641 ATAQLFILGCTWCLGILQVGPAARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWS 700
Query: 860 TGKTKPSSQSQTSRILLSSMPSASK 884
G K ++S+ + S+ SK
Sbjct: 701 KGIRKLKTESEMHTLSSSAKADTSK 725
Score = 88.6 bits (218), Expect = 2e-17
Identities = 59/162 (36%), Positives = 78/162 (48%), Gaps = 24/162 (14%)
Query: 74 PGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDI 133
PG +D C++ C +SSC N + C C GFSS + P + +C DI
Sbjct: 19 PGAETQDSRGCARW---CPQDSSCVNATA---CRCNPGFSSFSEIITTPME----TCDDI 68
Query: 134 NECLTSSV--CPEHSDCVNSMGSYSCSCQVGF----------ISRNSTCEDVDECAD-PR 180
NEC T S C + SDC N+ GSY C C G+ +TC+DVDEC+
Sbjct: 69 NECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECSSGQH 128
Query: 181 ACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDI 222
C C NTVG+YSC C PG++ G + Q CED+
Sbjct: 129 QCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQ-KDTVCEDM 169
Score = 62.0 bits (149), Expect = 2e-09
Identities = 30/94 (31%), Positives = 43/94 (45%), Gaps = 4/94 (4%)
Query: 41 CPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVR-CKDIDECSQSPQPCGPNSSCKN 99
C ++ C NT SY C C G+ +G FK+ C+D+DECS C ++ C N
Sbjct: 79 CGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECSSGQHQCDSSTVCFN 138
Query: 100 LSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDI 133
G Y C C G+ G +P + C D+
Sbjct: 139 TVGSYSCRCRPGWKPRHG---IPNNQKDTVCEDM 169
>gi|23397693 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform g [Homo sapiens]
Length = 719
Score = 422 bits (1085), Expect = e-118
Identities = 260/732 (35%), Positives = 385/732 (52%), Gaps = 59/732 (8%)
Query: 171 EDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTEMCP 230
+D CA R CP+ ++C N +C CNPGF S S ++ +C+DI+EC +
Sbjct: 24 QDSRGCA--RWCPQDSSCVNAT---ACRCNPGFSSFSEIITTP--METCDDINECATLSK 76
Query: 231 IN----STCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVE-CRDIDECRQDPSTCGPNSIC 285
++ S C NT GSY C C PG+ P +G F ++ C+D+DEC C +++C
Sbjct: 77 VSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECSSGQHQCDSSTVC 136
Query: 286 TNALGSYSCGCIAGFHPNPEGSQKDGNFSCQRVLFKCKEDVIPDNKQIQQCQEGT--AVK 343
N +GSYSC C P + G IP+N++ C++ T
Sbjct: 137 FNTVGSYSCRC------RPGWKPRHG---------------IPNNQKDTVCEDMTFSTWT 175
Query: 344 PAYVSFCAQINNIFSVLDKVCEN------KTTVVSLKNTTESFVPVLKQISTWTKFTKEE 397
P ++ F + + + T+ S+ + + + T + +
Sbjct: 176 PPPGVHSQTLSRFFDKVQDLGRDYKPGLANNTIQSILQALDELLEAPGDLETLPRLQQHC 235
Query: 398 TSSLATVFLESVESMTLASFWKPSANITPAVRTEY-LDIESKVINKECSEENVTLDLVAK 456
+S LE V + N + TE L+++ +V +N +
Sbjct: 236 VASHLLDGLEDVLRGLSKNLSNGLLNFSYPAGTELSLEVQKQVDRSVTLRQNQAV----- 290
Query: 457 GDKMKIGCSTIEESESTETTGVAFVSFVGMESVLNERFFKDHQAPLTTSEIKLKMNSRVV 516
M++ + ++S + + + +E + HQ L L S V+
Sbjct: 291 ---MQLDWNQAQKSGDPGMGKLLAEAPLVLEPEKQMLLHETHQGLLQDGSPILL--SDVI 345
Query: 517 GGIMTGEKKDGFSDPIIYTLEN--IQPKQKFERPICVSWSTDVKG-GRWTSFGCVILEAS 573
++ S P+ +T + + P+QK +CV W G G W + GC +
Sbjct: 346 SAFLSNNDTQNLSSPVTFTFSHRSVIPRQKV---LCVFWEHGQNGCGHWATTGCSTIGTR 402
Query: 574 ETYTICSCNQMANLAVIMASGELTM-DFSLYIISHVGIIISLVCLVLAIATFLLCRSIRN 632
+T TIC C +++ AV+MA ++ D L +I+++G+ +SL+CL+LA TFLLC++I+N
Sbjct: 403 DTSTICRCTHLSSFAVLMAHYDVQEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQN 462
Query: 633 HNTYLHLHLCVCLLLAKTLFLAGIHKTDNKMGCAIIAGFLHYLFLACFFWMLVEAVILFL 692
+T LHL L +CL LA LFL I +T +K+ C+IIAG LHYL+LA WML+EA+ LFL
Sbjct: 463 TSTSLHLQLSLCLFLAHLLFLVAIDQTGHKVLCSIIAGTLHYLYLATLTWMLLEALYLFL 522
Query: 693 MVRNLKVVNYFSSRNIKMLHICAFGYGLPMLVVVISASVQPQGYGMHNRCWLNTETGFIW 752
RNL VVNY S + GYG+P + V ISA+ +P YG +RCWL E GFIW
Sbjct: 523 TARNLTVVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIW 582
Query: 753 SFLGPVCTVIVINSLLLTWTLWILRQRLSSVNAEVSTLKDTRLLTFKAFAQLFILGCSWV 812
FLGPVC + +N +L TLWIL+ RLSS+N+EVSTL++TR+L FKA AQLFILGC+W
Sbjct: 583 GFLGPVCAIFSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWC 642
Query: 813 LGIFQIGPVAGVMAYLFTIINSLQGAFIFLIHCLLNGQVREEYKRWITGKTKPSSQSQTS 872
LGI Q+GP A VMAYLFTIINSLQG FIFL++CLL+ QVRE+Y +W G K ++S+
Sbjct: 643 LGILQVGPAARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWSKGIRKLKTESEMH 702
Query: 873 RILLSSMPSASK 884
+ S+ SK
Sbjct: 703 TLSSSAKADTSK 714
Score = 88.6 bits (218), Expect = 2e-17
Identities = 59/162 (36%), Positives = 78/162 (48%), Gaps = 24/162 (14%)
Query: 74 PGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDI 133
PG +D C++ C +SSC N + C C GFSS + P + +C DI
Sbjct: 19 PGAETQDSRGCARW---CPQDSSCVNATA---CRCNPGFSSFSEIITTPME----TCDDI 68
Query: 134 NECLTSSV--CPEHSDCVNSMGSYSCSCQVGF----------ISRNSTCEDVDECAD-PR 180
NEC T S C + SDC N+ GSY C C G+ +TC+DVDEC+
Sbjct: 69 NECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECSSGQH 128
Query: 181 ACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDI 222
C C NTVG+YSC C PG++ G + Q CED+
Sbjct: 129 QCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQ-KDTVCEDM 169
Score = 62.4 bits (150), Expect = 2e-09
Identities = 38/143 (26%), Positives = 53/143 (37%), Gaps = 49/143 (34%)
Query: 217 ASCEDIDECTEMCPINSTCT---------------------------------------- 236
A +D C CP +S+C
Sbjct: 21 AETQDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITTPMETCDDINECATLSKVSCG 80
Query: 237 ------NTPGSYFCTCHPGFAPSNGQLNFTDQGVE-CRDIDECRQDPSTCGPNSICTNAL 289
NT GSY C C PG+ P +G F ++ C+D+DEC C +++C N +
Sbjct: 81 KFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECSSGQHQCDSSTVCFNTV 140
Query: 290 GSYSCGCIAGFHPNP--EGSQKD 310
GSYSC C G+ P +QKD
Sbjct: 141 GSYSCRCRPGWKPRHGIPNNQKD 163
Score = 62.0 bits (149), Expect = 2e-09
Identities = 30/94 (31%), Positives = 43/94 (45%), Gaps = 4/94 (4%)
Query: 41 CPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVR-CKDIDECSQSPQPCGPNSSCKN 99
C ++ C NT SY C C G+ +G FK+ C+D+DECS C ++ C N
Sbjct: 79 CGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECSSGQHQCDSSTVCFN 138
Query: 100 LSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDI 133
G Y C C G+ G +P + C D+
Sbjct: 139 TVGSYSCRCRPGWKPRHG---IPNNQKDTVCEDM 169
>gi|68508955 CD97 antigen isoform 3 precursor [Homo sapiens]
Length = 786
Score = 412 bits (1059), Expect = e-115
Identities = 250/784 (31%), Positives = 401/784 (51%), Gaps = 98/784 (12%)
Query: 142 CPEHSDCVNSMGSYSCSCQVGFISRNS-------TCEDVDECADPR--ACPEHATCNNTV 192
CP++S CVN+ +C C GF S + TC+D++ECA P +C + + C NT
Sbjct: 30 CPQNSSCVNAT---ACRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTE 86
Query: 193 GNYSCFCNPGFESSSGHLSFQG-LKASCEDIDECTE---MCPINSTCTNTPGSYFCTCHP 248
G+Y C C+PG+E SG +F+ + +C+D+DEC + +C TC NT GSY C C P
Sbjct: 87 GSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLP 146
Query: 249 GFA--PSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEG 306
GF P + ++ C D+DEC C +++C N +GSYSC C G+ P
Sbjct: 147 GFKFIPEDPKV--------CTDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGI 198
Query: 307 SQKDGNFSCQRVLFKC--------KEDVIPDNKQIQQCQEGTAVKPAYVSFCAQINNIFS 358
+ C+ + F + + ++Q + A V+ I N+
Sbjct: 199 PNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTSSAEVT----IQNVIK 254
Query: 359 VLDKVCENKTTVVSLKNTTESFVPVLKQISTWTKFTKEETSSLATVFLESVESMTLASFW 418
++D++ E V +L PV I+T + S+L + +S+ F
Sbjct: 255 LVDELMEAPGDVEALAP------PVRHLIAT------QLLSNLEDIMRILAKSLPKGPF- 301
Query: 419 KPSANITPAVRTEYLDIESKVINKECSEENVTLDLVAKGDKMKIGCSTIEESESTETTGV 478
I+P+ + E ++ +E ++NVT+ +MK+ + +E
Sbjct: 302 ---TYISPS------NTELTLMIQERGDKNVTMG--QSSARMKLNWAVAAGAEDPGPAVA 350
Query: 479 AFVSFVGMESVLNERFFKDHQAPLTTSE---------IKLKMNSRVVGGIMTGEKKDGFS 529
+S M ++L H E ++L+ S V ++ +
Sbjct: 351 GILSIQNMTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELN 410
Query: 530 DPIIYTLENIQ---------PKQKFERP------ICVSWSTDV-KGGRWTSFGCVILEAS 573
PI++ +++ P K P +C W +D +GG W + GC +L +
Sbjct: 411 SPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSK 470
Query: 574 ETYTICSCNQMANLAVIMASGELTMDFSLYIISHVGIIISLVCLVLAIATFLLCRSIRNH 633
T C C+ +++ A++MA ++ D+ L +I+ VG+ +SL CL+L I TFLL R I+
Sbjct: 471 NGSTTCQCSHLSSFAILMAHYDVE-DWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGS 529
Query: 634 NTYLHLHLCVCLLLAKTLFLAGIHKTDNKMG--CAIIAGFLHYLFLACFFWMLVEAVILF 691
T +HLHLC+CL + T+FLAGI ++G C ++AG LHY FLA F WM +E + L+
Sbjct: 530 RTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELY 589
Query: 692 LMVRNLKVVNYFSSRNIKMLHICAFGYGLPMLVVVISASVQPQGYGMHNRCWLNTETGFI 751
+V V F + + +C GYG+P+L+V +SA++ +GYG CWL+ E GF+
Sbjct: 590 FLV-----VRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFL 644
Query: 752 WSFLGPVCTVIVINSLLLTWTLWILRQRLSSVNAEVSTLKDTRLLTFKAFAQLFILGCSW 811
WSFLGPV +I+ N+++ T+W L Q+ S +N ++ LK R LT A AQLF+LGC+W
Sbjct: 645 WSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTW 704
Query: 812 VLGIFQIGPVAGVMAYLFTIINSLQGAFIFLIHCLLNGQVREEYKRW---ITGKTKPSSQ 868
V G+F + V+ Y+FTI+N LQGAF++L+HCLLN +VREEY++W + G +K S
Sbjct: 705 VFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWACLVAGGSKYSEF 764
Query: 869 SQTS 872
+ T+
Sbjct: 765 TSTT 768
Score = 95.5 bits (236), Expect = 2e-19
Identities = 50/143 (34%), Positives = 73/143 (51%), Gaps = 18/143 (12%)
Query: 41 CPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVR-CKDIDECSQSPQPCGPNSSCKN 99
C ++ C NT SY C C G+ +G FK+ C+D+DEC Q+P+ C +C N
Sbjct: 76 CGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVN 135
Query: 100 LSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSS-VCPEHSDCVNSMGSYSCS 158
G Y C CL GF ++P P CTD++EC + C + C N++GSYSC
Sbjct: 136 TLGSYTCQCLPGFK------FIPEDPK--VCTDVDECSSGQHQCDSSTVCFNTVGSYSCR 187
Query: 159 CQVGFISR--------NSTCEDV 173
C+ G+ R ++ CED+
Sbjct: 188 CRPGWKPRHGIPNNQKDTVCEDM 210
Score = 65.9 bits (159), Expect = 2e-10
Identities = 38/112 (33%), Positives = 49/112 (43%), Gaps = 16/112 (14%)
Query: 29 NTKGNNCRD-------STLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDI 81
N N C+D LC +Y TC NT+ SY C C GF +DP V C D+
Sbjct: 108 NESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIP-----EDPKV-CTDV 161
Query: 82 DECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDI 133
DECS C ++ C N G Y C C G+ G +P + C D+
Sbjct: 162 DECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHG---IPNNQKDTVCEDM 210
>gi|23397687 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform d [Homo sapiens]
Length = 681
Score = 387 bits (994), Expect = e-107
Identities = 254/697 (36%), Positives = 364/697 (52%), Gaps = 70/697 (10%)
Query: 217 ASCEDIDECTEMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQ-D 275
A +D C CP +S+C N C C+PGF+ + + T C DI+EC
Sbjct: 21 AETQDSRGCARWCPQDSSCVNATA---CRCNPGFSSFSEII--TTPMETCDDINECATLS 75
Query: 276 PSTCGPNSICTNALGSYSCGCIAGFHP--NPEGSQKDGNFSCQRVLFKCKEDVIPDNKQ- 332
+CG S C N GSY C C G+ P + + + +CQ + F + Q
Sbjct: 76 KVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDMTFSTWTPPPGVHSQT 135
Query: 333 ----IQQCQE-GTAVKPAYVSFCAQINNIFSVLDKVCENKTTVVSLKNTTESFVPVLKQI 387
+ Q+ G KP + I +I LD++ E + +L P L+Q
Sbjct: 136 LSRFFDKVQDLGRDYKPGLAN--NTIQSILQALDELLEAPGDLETL--------PRLQQ- 184
Query: 388 STWTKFTKEETSSLATVFLESVESMTLASFWKPSAN-----ITPAVRTEYLDIESKVINK 442
+A+ L+ +E + L K +N PA L+++ +V
Sbjct: 185 -----------HCVASHLLDGLEDV-LRGLSKNLSNGLLNFSYPAGTELSLEVQKQVDRS 232
Query: 443 ECSEENVTLDLVAKGDKMKIGCSTIEESESTETTGVAFVSFVGMESVLNER--------- 493
+N + M++ + ++S + V VS GM +L E
Sbjct: 233 VTLRQNQAV--------MQLDWNQAQKSGDPGPSVVGLVSIPGMGKLLAEAPLVLEPEKQ 284
Query: 494 --FFKDHQAPLTTSEIKLKMNSRVVGGIMTGEKKDGFSDPIIYTLEN--IQPKQKFERPI 549
+ HQ L L S V+ ++ S P+ +T + + P+QK +
Sbjct: 285 MLLHETHQGLLQDGSPILL--SDVISAFLSNNDTQNLSSPVTFTFSHRSVIPRQKV---L 339
Query: 550 CVSWSTDVKG-GRWTSFGCVILEASETYTICSCNQMANLAVIMASGELTM-DFSLYIISH 607
CV W G G W + GC + +T TIC C +++ AV+MA ++ D L +I++
Sbjct: 340 CVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTHLSSFAVLMAHYDVQEEDPVLTVITY 399
Query: 608 VGIIISLVCLVLAIATFLLCRSIRNHNTYLHLHLCVCLLLAKTLFLAGIHKTDNKMGCAI 667
+G+ +SL+CL+LA TFLLC++I+N +T LHL L +CL LA LFL I +T +K+ C+I
Sbjct: 400 MGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFLAHLLFLVAIDQTGHKVLCSI 459
Query: 668 IAGFLHYLFLACFFWMLVEAVILFLMVRNLKVVNYFSSRNIKMLHICAFGYGLPMLVVVI 727
IAG LHYL+LA WML+EA+ LFL RNL VVNY S + GYG+P + V I
Sbjct: 460 IAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVTVAI 519
Query: 728 SASVQPQGYGMHNRCWLNTETGFIWSFLGPVCTVIVINSLLLTWTLWILRQRLSSVNAEV 787
SA+ +P YG +RCWL E GFIW FLGPVC + +N +L TLWIL+ RLSS+N+EV
Sbjct: 520 SAASRPHLYGTPSRCWLQPEKGFIWGFLGPVCAIFSVNLVLFLVTLWILKNRLSSLNSEV 579
Query: 788 STLKDTRLLTFKAFAQLFILGCSWVLGIFQIGPVAGVMAYLFTIINSLQGAFIFLIHCLL 847
STL++TR+L FKA AQLFILGC+W LGI Q+GP A VMAYLFTIINSLQG FIFL++CLL
Sbjct: 580 STLRNTRMLAFKATAQLFILGCTWCLGILQVGPAARVMAYLFTIINSLQGVFIFLVYCLL 639
Query: 848 NGQVREEYKRWITGKTKPSSQSQTSRILLSSMPSASK 884
+ QVRE+Y +W G K ++S+ + S+ SK
Sbjct: 640 SQQVREQYGKWSKGIRKLKTESEMHTLSSSAKADTSK 676
Score = 65.9 bits (159), Expect = 2e-10
Identities = 37/104 (35%), Positives = 56/104 (53%), Gaps = 12/104 (11%)
Query: 171 EDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTEMCP 230
+D CA R CP+ ++C N +C CNPGF S S ++ +C+DI+EC +
Sbjct: 24 QDSRGCA--RWCPQDSSCVNAT---ACRCNPGFSSFSEIITTP--METCDDINECATLSK 76
Query: 231 IN----STCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVE-CRDI 269
++ S C NT GSY C C PG+ P +G F ++ C+D+
Sbjct: 77 VSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDM 120
Score = 64.3 bits (155), Expect = 5e-10
Identities = 39/108 (36%), Positives = 56/108 (51%), Gaps = 19/108 (17%)
Query: 142 CPEHSDCVNSMGSYSCSCQVGFISRNS-------TCEDVDECA--DPRACPEHATCNNTV 192
CP+ S CVN+ +C C GF S + TC+D++ECA +C + + C NT
Sbjct: 33 CPQDSSCVNAT---ACRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTE 89
Query: 193 GNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTEMCPINSTCTNTPG 240
G+Y C C+PG+E SG +F+ E + C +M ST T PG
Sbjct: 90 GSYDCVCSPGYEPVSGAKTFKN-----ESENTCQDM--TFSTWTPPPG 130
Score = 54.3 bits (129), Expect = 5e-07
Identities = 35/92 (38%), Positives = 46/92 (50%), Gaps = 12/92 (13%)
Query: 74 PGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDI 133
PG +D C++ C +SSC N + C C GFSS + P + +C DI
Sbjct: 19 PGAETQDSRGCARW---CPQDSSCVNATA---CRCNPGFSSFSEIITTPME----TCDDI 68
Query: 134 NECLTSSV--CPEHSDCVNSMGSYSCSCQVGF 163
NEC T S C + SDC N+ GSY C C G+
Sbjct: 69 NECATLSKVSCGKFSDCWNTEGSYDCVCSPGY 100
Score = 47.4 bits (111), Expect = 6e-05
Identities = 30/94 (31%), Positives = 40/94 (42%), Gaps = 7/94 (7%)
Query: 41 CPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQ-SPQPCGPNSSCKN 99
CP ++C N C C GF S+ P C DI+EC+ S CG S C N
Sbjct: 33 CPQDSSCVNATA---CRCNPGF--SSFSEIITTPMETCDDINECATLSKVSCGKFSDCWN 87
Query: 100 LSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDI 133
G Y C C G+ +G + N +C D+
Sbjct: 88 TEGSYDCVCSPGYEPVSGAKTFKNESEN-TCQDM 120
Score = 34.7 bits (78), Expect = 0.40
Identities = 16/51 (31%), Positives = 25/51 (49%), Gaps = 1/51 (1%)
Query: 41 CPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVR-CKDIDECSQSPQP 90
C ++ C NT SY C C G+ +G FK+ C+D+ + +P P
Sbjct: 79 CGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDMTFSTWTPPP 129
>gi|17978489 CD97 antigen isoform 2 precursor [Homo sapiens]
Length = 742
Score = 380 bits (977), Expect = e-105
Identities = 234/745 (31%), Positives = 378/745 (50%), Gaps = 84/745 (11%)
Query: 171 EDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTEMCP 230
+D CA R CP++++C N +C CNPGF S S ++ +C+DI+EC
Sbjct: 21 QDSRGCA--RWCPQNSSCVNAT---ACRCNPGFSSFSEIITTP--TETCDDINECATPSK 73
Query: 231 IN----STCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVE-CRDIDECRQDPSTCGPNSIC 285
++ S C NT GSY C C PG+ P +G F ++ C+D+DEC C +++C
Sbjct: 74 VSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECSSGQHQCDSSTVC 133
Query: 286 TNALGSYSCGCIAGFHPNPEGSQKDGNFSCQRVLFKC--------KEDVIPDNKQIQQCQ 337
N +GSYSC C G+ P + C+ + F + + ++Q
Sbjct: 134 FNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLG 193
Query: 338 EGTAVKPAYVSFCAQINNIFSVLDKVCENKTTVVSLKNTTESFVPVLKQISTWTKFTKEE 397
+ A V+ I N+ ++D++ E V +L PV I+T +
Sbjct: 194 RDSKTSSAEVT----IQNVIKLVDELMEAPGDVEALAP------PVRHLIAT------QL 237
Query: 398 TSSLATVFLESVESMTLASFWKPSANITPAVRTEYLDIESKVINKECSEENVTLDLVAKG 457
S+L + +S+ F I+P+ + E ++ +E ++NVT+
Sbjct: 238 LSNLEDIMRILAKSLPKGPF----TYISPS------NTELTLMIQERGDKNVTMG--QSS 285
Query: 458 DKMKIGCSTIEESESTETTGVAFVSFVGMESVLNERFFKDHQAPLTTSE---------IK 508
+MK+ + +E +S M ++L H E ++
Sbjct: 286 ARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLNLHSKKQAELEEIYESSIRGVQ 345
Query: 509 LKMNSRVVGGIMTGEKKDGFSDPIIYTLENIQ---------PKQKFERP------ICVSW 553
L+ S V ++ + PI++ +++ P K P +C W
Sbjct: 346 LRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFW 405
Query: 554 STDV-KGGRWTSFGCVILEASETYTICSCNQMANLAVIMASGELTMDFSLYIISHVGIII 612
+D +GG W + GC +L + T C C+ +++ A++MA ++ D+ L +I+ VG+ +
Sbjct: 406 KSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHYDVE-DWKLTLITRVGLAL 464
Query: 613 SLVCLVLAIATFLLCRSIRNHNTYLHLHLCVCLLLAKTLFLAGIHKTDNKMG--CAIIAG 670
SL CL+L I TFLL R I+ T +HLHLC+CL + T+FLAGI ++G C ++AG
Sbjct: 465 SLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAG 524
Query: 671 FLHYLFLACFFWMLVEAVILFLMVRNLKVVNYFSSRNIKMLHICAFGYGLPMLVVVISAS 730
LHY FLA F WM +E + L+ +V V F + + +C GYG+P+L+V +SA+
Sbjct: 525 LLHYCFLAAFCWMSLEGLELYFLV-----VRVFQGQGLSTRWLCLIGYGVPLLIVGVSAA 579
Query: 731 VQPQGYGMHNRCWLNTETGFIWSFLGPVCTVIVINSLLLTWTLWILRQRLSSVNAEVSTL 790
+ +GYG CWL+ E GF+WSFLGPV +I+ N+++ T+W L Q+ S +N ++ L
Sbjct: 580 IYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKL 639
Query: 791 KDTRLLTFKAFAQLFILGCSWVLGIFQIGPVAGVMAYLFTIINSLQGAFIFLIHCLLNGQ 850
K R LT A AQLF+LGC+WV G+F + V+ Y+FTI+N LQGAF++L+HCLLN +
Sbjct: 640 KKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKK 699
Query: 851 VREEYKRW---ITGKTKPSSQSQTS 872
VREEY++W + G +K S + T+
Sbjct: 700 VREEYRKWACLVAGGSKYSEFTSTT 724
Score = 91.3 bits (225), Expect = 4e-18
Identities = 60/162 (37%), Positives = 78/162 (48%), Gaps = 24/162 (14%)
Query: 74 PGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDI 133
PG +D C++ C NSSC N + C C GFSS + P + +C DI
Sbjct: 16 PGAETQDSRGCARW---CPQNSSCVNATA---CRCNPGFSSFSEIITTPTE----TCDDI 65
Query: 134 NECLTSSV--CPEHSDCVNSMGSYSCSCQVGF----------ISRNSTCEDVDECAD-PR 180
NEC T S C + SDC N+ GSY C C G+ +TC+DVDEC+
Sbjct: 66 NECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECSSGQH 125
Query: 181 ACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDI 222
C C NTVG+YSC C PG++ G + Q CED+
Sbjct: 126 QCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQ-KDTVCEDM 166
Score = 62.0 bits (149), Expect = 2e-09
Identities = 30/94 (31%), Positives = 43/94 (45%), Gaps = 4/94 (4%)
Query: 41 CPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVR-CKDIDECSQSPQPCGPNSSCKN 99
C ++ C NT SY C C G+ +G FK+ C+D+DECS C ++ C N
Sbjct: 76 CGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECSSGQHQCDSSTVCFN 135
Query: 100 LSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDI 133
G Y C C G+ G +P + C D+
Sbjct: 136 TVGSYSCRCRPGWKPRHG---IPNNQKDTVCEDM 166
>gi|148806925 EGF, latrophilin and seven transmembrane domain
containing 1 [Homo sapiens]
Length = 690
Score = 291 bits (745), Expect = 2e-78
Identities = 215/695 (30%), Positives = 333/695 (47%), Gaps = 63/695 (9%)
Query: 182 CPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDEC---TEMCPINSTCTNT 238
C +A C G +C+CN GF + + CED +EC T+ C N+ CTNT
Sbjct: 27 CLPNAKCEIRNGIEACYCNMGFSGNGVTI--------CEDDNECGNLTQSCGENANCTNT 78
Query: 239 PGSYFCTCHPGFAPSNGQLNF-TDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCI 297
GSY+C C PGF S+ Q F T+ G C + C +++C A + + I
Sbjct: 79 EGSYYCMCVPGFRSSSNQDRFITNDGTVC-----IENVNANCHLDNVCIAANINKTLTKI 133
Query: 298 AGFHPNPEGSQKDGNFSCQRVLFKCKEDVIPDN--KQIQQCQEGTAVKPAYVSFCAQINN 355
S K+ Q V D+ P + I+ E + S NN
Sbjct: 134 R--------SIKEPVALLQEVYRNSVTDLSPTDIITYIEILAESS-------SLLGYKNN 178
Query: 356 IFSVLDKVCENKTTVVSLKNTTESFVPVLKQISTWTKFTKEETSSLATVFLESVESMTLA 415
S D + + +T+ T +FV W K + + T + +VE TL
Sbjct: 179 TISAKDTL--SNSTLTEFVKTVNNFVQ-RDTFVVWDKLSVNHRRTHLTKLMHTVEQATLR 235
Query: 416 SFWKPSANITPAVRTEYLDIESKVI-----NKECSEENVTLDLVAKGDKMKIGCSTIEES 470
S T T DI KV N + ++ +D GD + I
Sbjct: 236 I--SQSFQKTTEFDTNSTDIALKVFFFDSYNMKHIHPHMNMD----GDYINIFPKRKAAY 289
Query: 471 ESTETTGVAFVSFVGMESVL--NERFFKDHQAPLTTSEIKLKMNSRVVGGIMTGEKKDGF 528
+S VAFV + + +L ++ F Q SE + ++ S V+ M+ +
Sbjct: 290 DSNGNVAVAFVYYKSIGPLLSSSDNFLLKPQ-NYDNSEEEERVISSVISVSMSSNPPTLY 348
Query: 529 S-DPIIYTLENIQPKQKFERPICVSW--STDVKGGRWTSFGCVILEASETYTICSCNQMA 585
+ I +TL + + ++ R +C W S D G W+S GC + ++ET+T C CN +
Sbjct: 349 ELEKITFTLSHRKVTDRY-RSLCAFWNYSPDTMNGSWSSEGCELTYSNETHTSCRCNHLT 407
Query: 586 NLAVIMASGEL--TMDFSLYI-ISHVGIIISLVCLVLAIATFLLCRSIRNHNTYLHLHLC 642
+ A++M+SG D+++ I+ +GIIISL+CL + I TF I++ T +H +LC
Sbjct: 408 HFAILMSSGPSIGIKDYNILTRITQLGIIISLICLAICIFTFWFFSEIQSTRTTIHKNLC 467
Query: 643 VCLLLAKTLFLAGIHKTDNKMGCAIIAGFLHYLFLACFFWMLVEAVILFLMVRNLKVVNY 702
L LA+ +FL GI+ NK+ C+IIAG LHY FLA F WM +E + L+L+V +
Sbjct: 468 CSLFLAELVFLVGINTNTNKLFCSIIAGLLHYFFLAAFAWMCIEGIHLYLIVVGVIYNKG 527
Query: 703 FSSRNIKMLHICAFGYGLPMLVVVISASVQPQGYGMHNRCWLNTETGFIWSFLGPVCTVI 762
F +N + FGY P +VV SA++ + YG CWL+TE FIWSF+GP C +I
Sbjct: 528 FLHKNFYI-----FGYLSPAVVVGFSAALGYRYYGTTKVCWLSTENNFIWSFIGPACLII 582
Query: 763 VINSLLLTWTLWILRQRLSSVNAEVSTLKDTRLLTFKAFAQLFILGCSWVLGIFQIGPVA 822
++N L ++ + + + + EVS ++ R A A LF+LG +W+ G+ + +
Sbjct: 583 LVNLLAFGVIIYKVFRHTAGLKPEVSCFENIRSCARGALALLFLLGTTWIFGVLHVVHAS 642
Query: 823 GVMAYLFTIINSLQGAFIFLIHCLLNGQVREEYKR 857
V AYLFT+ N+ QG FIFL C+L+ +++EEY R
Sbjct: 643 VVTAYLFTVSNAFQGMFIFLFLCVLSRKIQEEYYR 677
Score = 65.9 bits (159), Expect = 2e-10
Identities = 40/119 (33%), Positives = 58/119 (48%), Gaps = 13/119 (10%)
Query: 129 SCTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGFISRNST-CEDVDECAD-PRACPEHA 186
+C+ C T + C ++ C G +C C +GF T CED +EC + ++C E+A
Sbjct: 15 NCSYTQNC-TKTPCLPNAKCEIRNGIEACYCNMGFSGNGVTICEDDNECGNLTQSCGENA 73
Query: 187 TCNNTVGNYSCFCNPGFESSS---------GHLSFQGLKASCEDIDECTEMCPINSTCT 236
C NT G+Y C C PGF SSS G + + + A+C +D IN T T
Sbjct: 74 NCTNTEGSYYCMCVPGFRSSSNQDRFITNDGTVCIENVNANCH-LDNVCIAANINKTLT 131
Score = 56.2 bits (134), Expect = 1e-07
Identities = 36/110 (32%), Positives = 45/110 (40%), Gaps = 10/110 (9%)
Query: 34 NCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGP 93
NC T C A C C C GF S NG C+D +EC Q CG
Sbjct: 21 NCT-KTPCLPNAKCEIRNGIEACYCNMGF-SGNGVTI-------CEDDNECGNLTQSCGE 71
Query: 94 NSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDIN-ECLTSSVC 142
N++C N G Y C C+ GF S + D G ++N C +VC
Sbjct: 72 NANCTNTEGSYYCMCVPGFRSSSNQDRFITNDGTVCIENVNANCHLDNVC 121
>gi|163792198 latrophilin 3 precursor [Homo sapiens]
Length = 1469
Score = 262 bits (670), Expect = 9e-70
Identities = 163/520 (31%), Positives = 270/520 (51%), Gaps = 29/520 (5%)
Query: 387 ISTWTKFTKEETSSLATVFLESVESMTLASFWKPSANITPAVRTEYLDIESKVINKECSE 446
++ W T + AT+ L +VE T+ + +E ++ E +
Sbjct: 651 LNAWRDLTTSDQLRAATMLLHTVEESAFVLADNLLKTDIVRENTDNIKLEVARLSTEGNL 710
Query: 447 ENVTL-DLVAKGDKMKIGCSTIEESESTETTGVAFVSFVGMESVLNER--FFKDHQAPLT 503
E++ + + G +++ +T++++ VAFV + + L+ K L+
Sbjct: 711 EDLKFPENMGHGSTIQLSANTLKQNGRNGEIRVAFVLYNNLGPYLSTENASMKLGTEALS 770
Query: 504 TSEIKLKMNSRVVGGIMTGE--KKDGFSDPIIYTLENIQPKQKFERPICVSWSTDVKG-- 559
T+ + +NS V+ + E K +DP+++T+++I+ ++ P C WS +
Sbjct: 771 TNHSVI-VNSPVITAAINKEFSNKVYLADPVVFTVKHIKQSEENFNPNCSFWSYSKRTMT 829
Query: 560 GRWTSFGCVILEASETYTICSCNQMANLAVIMASGEL-----TMDFSLYIISHVGIIISL 614
G W++ GC +L ++T+T CSCN + N AV+MA E+ D L +I+ VGI++SL
Sbjct: 830 GYWSTQGCRLLTTNKTHTTCSCNHLTNFAVLMAHVEVKHSDAVHDLLLDVITWVGILLSL 889
Query: 615 VCLVLAIATFLLCRSIRNHNTYLHLHLCVCLLLAKTLFLAGIHKTDNKMGCAIIAGFLHY 674
VCL++ I TF R +++ +H +LC+ L +A+ LFL GI++TD + CA+ A LH+
Sbjct: 890 VCLLICIFTFCFFRGLQSDRNTIHKNLCISLFVAELLFLIGINRTDQPIACAVFAALLHF 949
Query: 675 LFLACFFWMLVEAVILFLMVRNLKVVNYFSSRNIKMLHICAFGYGLPMLVVVISASVQPQ 734
FLA F WM +E V L++M +V F S + + + GYG+P L+V +SA+V +
Sbjct: 950 FFLAAFTWMFLEGVQLYIM-----LVEVFESEHSRRKYFYLVGYGMPALIVAVSAAVDYR 1004
Query: 735 GYGMHNRCWLNTETGFIWSFLGPVCTVIVINSLLLTWTLWILRQRLSSVNAEVSTL---- 790
YG CWL +T FIWSF+GP +I++N + L L+ + + + E L
Sbjct: 1005 SYGTDKVCWLRLDTYFIWSFIGPATLIIMLNVIFLGIALYKMFHHTAILKPESGCLDNIN 1064
Query: 791 -KDTRLL----TFKAFAQLFILGCSWVLGIFQIGPVAGVMAYLFTIINSLQGAFIFLIHC 845
+D R A A L +LG +W G+ I +MAYLFTI NSLQG FIF+ HC
Sbjct: 1065 YEDNRPFIKSWVIGAIALLCLLGLTWAFGLMYINESTVIMAYLFTIFNSLQGMFIFIFHC 1124
Query: 846 LLNGQVREEYKRWITGKTKPSSQSQTSRILLSSMPSASKT 885
+L +VR+EY + + +T S T + S S S+T
Sbjct: 1125 VLQKKVRKEYGKCL--RTHCCSGKSTESSIGSGKTSGSRT 1162
>gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens]
Length = 1474
Score = 254 bits (650), Expect = 2e-67
Identities = 156/486 (32%), Positives = 250/486 (51%), Gaps = 23/486 (4%)
Query: 387 ISTWTKFTKEETSSLATVFLESVE--SMTLASFWKPSANITPAVRTEYLDIESKVINKEC 444
+ +W E AT+ L+ +E + LA + A A E + +E V+N E
Sbjct: 633 LESWKDMNATEQVHTATMLLDVLEEGAFLLADNVREPARFLAA--KENVVLEVTVLNTEG 690
Query: 445 SEENVTL--DLVAKGDKMKIGCSTIEESESTETTGVAFVSFVGMESVLNERF----FKDH 498
+ + + + + +++ TI+++ V F+ + + L+
Sbjct: 691 QVQELVFPQEEYPRKNSIQLSAKTIKQNSRNGVVKVVFILYNNLGLFLSTENATVKLAGE 750
Query: 499 QAPLTTSEIKLKMNSRVVGGIMTGEKKDGF-SDPIIYTLENIQPKQKFERPICVSWSTDV 557
P L +NS+V+ + E F DP+I+T+ +++ K F C W+
Sbjct: 751 AGPGGPGGASLVVNSQVIAASINKESSRVFLMDPVIFTVAHLEDKNHFNAN-CSFWNYSE 809
Query: 558 KG--GRWTSFGCVILEASETYTICSCNQMANLAVIMASGELTM----DFSLYIISHVGII 611
+ G W++ GC ++E+++T+T C+C+ + N AV+MA E+ + L +I+ VGI+
Sbjct: 810 RSMLGYWSTQGCRLVESNKTHTTCACSHLTNFAVLMAHREIYQGRINELLLSVITWVGIV 869
Query: 612 ISLVCLVLAIATFLLCRSIRNHNTYLHLHLCVCLLLAKTLFLAGIHKTDNKMGCAIIAGF 671
ISLVCL + I+TF R ++ +H +LC+ L LA+ LFL GI KT ++ C I AG
Sbjct: 870 ISLVCLAICISTFCFLRGLQTDRNTIHKNLCINLFLAELLFLVGIDKTQYEIACPIFAGL 929
Query: 672 LHYLFLACFFWMLVEAVILFLMVRNLKVVNYFSSRNIKMLHICAFGYGLPMLVVVISASV 731
LHY FLA F W+ +E V L+L++ V F S + + GY P LVV I+A++
Sbjct: 930 LHYFFLAAFSWLCLEGVHLYLLL-----VEVFESEYSRTKYYYLGGYCFPALVVGIAAAI 984
Query: 732 QPQGYGMHNRCWLNTETGFIWSFLGPVCTVIVINSLLLTWTLWILRQRLSSVNAEVSTLK 791
+ YG CWL + FIWSF+GPV VIV+N + L TL + + S + + S L
Sbjct: 985 DYRSYGTEKACWLRVDNYFIWSFIGPVSFVIVVNLVFLMVTLHKMIRSSSVLKPDSSRLD 1044
Query: 792 DTRLLTFKAFAQLFILGCSWVLGIFQIGPVAGVMAYLFTIINSLQGAFIFLIHCLLNGQV 851
+ + A A LF+LG +W G+ I + VMAYLFT N+ QG FIF+ HC L +V
Sbjct: 1045 NIKSWALGAIALLFLLGLTWAFGLLFINKESVVMAYLFTTFNAFQGVFIFVFHCALQKKV 1104
Query: 852 REEYKR 857
+EY +
Sbjct: 1105 HKEYSK 1110
>gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens]
Length = 1469
Score = 254 bits (650), Expect = 2e-67
Identities = 156/486 (32%), Positives = 250/486 (51%), Gaps = 23/486 (4%)
Query: 387 ISTWTKFTKEETSSLATVFLESVE--SMTLASFWKPSANITPAVRTEYLDIESKVINKEC 444
+ +W E AT+ L+ +E + LA + A A E + +E V+N E
Sbjct: 628 LESWKDMNATEQVHTATMLLDVLEEGAFLLADNVREPARFLAA--KENVVLEVTVLNTEG 685
Query: 445 SEENVTL--DLVAKGDKMKIGCSTIEESESTETTGVAFVSFVGMESVLNERF----FKDH 498
+ + + + + +++ TI+++ V F+ + + L+
Sbjct: 686 QVQELVFPQEEYPRKNSIQLSAKTIKQNSRNGVVKVVFILYNNLGLFLSTENATVKLAGE 745
Query: 499 QAPLTTSEIKLKMNSRVVGGIMTGEKKDGF-SDPIIYTLENIQPKQKFERPICVSWSTDV 557
P L +NS+V+ + E F DP+I+T+ +++ K F C W+
Sbjct: 746 AGPGGPGGASLVVNSQVIAASINKESSRVFLMDPVIFTVAHLEDKNHFNAN-CSFWNYSE 804
Query: 558 KG--GRWTSFGCVILEASETYTICSCNQMANLAVIMASGELTM----DFSLYIISHVGII 611
+ G W++ GC ++E+++T+T C+C+ + N AV+MA E+ + L +I+ VGI+
Sbjct: 805 RSMLGYWSTQGCRLVESNKTHTTCACSHLTNFAVLMAHREIYQGRINELLLSVITWVGIV 864
Query: 612 ISLVCLVLAIATFLLCRSIRNHNTYLHLHLCVCLLLAKTLFLAGIHKTDNKMGCAIIAGF 671
ISLVCL + I+TF R ++ +H +LC+ L LA+ LFL GI KT ++ C I AG
Sbjct: 865 ISLVCLAICISTFCFLRGLQTDRNTIHKNLCINLFLAELLFLVGIDKTQYEIACPIFAGL 924
Query: 672 LHYLFLACFFWMLVEAVILFLMVRNLKVVNYFSSRNIKMLHICAFGYGLPMLVVVISASV 731
LHY FLA F W+ +E V L+L++ V F S + + GY P LVV I+A++
Sbjct: 925 LHYFFLAAFSWLCLEGVHLYLLL-----VEVFESEYSRTKYYYLGGYCFPALVVGIAAAI 979
Query: 732 QPQGYGMHNRCWLNTETGFIWSFLGPVCTVIVINSLLLTWTLWILRQRLSSVNAEVSTLK 791
+ YG CWL + FIWSF+GPV VIV+N + L TL + + S + + S L
Sbjct: 980 DYRSYGTEKACWLRVDNYFIWSFIGPVSFVIVVNLVFLMVTLHKMIRSSSVLKPDSSRLD 1039
Query: 792 DTRLLTFKAFAQLFILGCSWVLGIFQIGPVAGVMAYLFTIINSLQGAFIFLIHCLLNGQV 851
+ + A A LF+LG +W G+ I + VMAYLFT N+ QG FIF+ HC L +V
Sbjct: 1040 NIKSWALGAIALLFLLGLTWAFGLLFINKESVVMAYLFTTFNAFQGVFIFVFHCALQKKV 1099
Query: 852 REEYKR 857
+EY +
Sbjct: 1100 HKEYSK 1105
>gi|6912464 latrophilin 2 precursor [Homo sapiens]
Length = 1403
Score = 251 bits (642), Expect = 2e-66
Identities = 152/483 (31%), Positives = 255/483 (52%), Gaps = 23/483 (4%)
Query: 387 ISTWTKFTKEETSSLATVFLESVE--SMTLA-SFWKPSANITPAVRTEYLDIESKVINKE 443
+ +W E + AT+ L+++E + LA + +P+ P TE + +E V++ E
Sbjct: 609 LESWKHMNSSEQAHTATMLLDTLEEGAFVLADNLLEPTRVSMP---TENIVLEVAVLSTE 665
Query: 444 CSEENVTLDLVAKG--DKMKIGCSTIEESESTETTGVAFVSFVGMESVLN-ERFFKDHQA 500
++ L KG +++ +T++++ + F+ + + L+ E A
Sbjct: 666 GQIQDFKFPLGIKGAGSSIQLSANTVKQNSRNGLAKLVFIIYRSLGQFLSTENATIKLGA 725
Query: 501 PLTTSEIKLKMNSRVVGGIMTGEKKDGF-SDPIIYTLENIQPKQKFERPICVSWSTDVKG 559
+ +NS V+ + E + +DP+++TL +I P F C W+ +
Sbjct: 726 DFIGRNSTIAVNSHVISVSINKESSRVYLTDPVLFTLPHIDPDNYFNAN-CSFWNYSERT 784
Query: 560 --GRWTSFGCVILEASETYTICSCNQMANLAVIMASGELTM-----DFSLYIISHVGIII 612
G W++ GC +++ ++T T C+C+ + N A++MA E+ + L +I+ VGI+I
Sbjct: 785 MMGYWSTQGCKLVDTNKTRTTCACSHLTNFAILMAHREIAYKDGVHELLLTVITWVGIVI 844
Query: 613 SLVCLVLAIATFLLCRSIRNHNTYLHLHLCVCLLLAKTLFLAGIHKTDNKMGCAIIAGFL 672
SLVCL + I TF R +++ +H +LC+ L +A+ +FL GI KT + C I AG L
Sbjct: 845 SLVCLAICIFTFCFFRGLQSDRNTIHKNLCINLFIAEFIFLIGIDKTKYAIACPIFAGLL 904
Query: 673 HYLFLACFFWMLVEAVILFLMVRNLKVVNYFSSRNIKMLHICAFGYGLPMLVVVISASVQ 732
H+ FLA F WM +E V L+LM+ V F S + + GY P VV +SA++
Sbjct: 905 HFFFLAAFAWMCLEGVQLYLML-----VEVFESEYSRKKYYYVAGYLFPATVVGVSAAID 959
Query: 733 PQGYGMHNRCWLNTETGFIWSFLGPVCTVIVINSLLLTWTLWILRQRLSSVNAEVSTLKD 792
+ YG CWL+ + FIWSF+GPV +I++N + L TL + + +++ + S L++
Sbjct: 960 YKSYGTEKACWLHVDNYFIWSFIGPVTFIILLNIIFLVITLCKMVKHSNTLKPDSSRLEN 1019
Query: 793 TRLLTFKAFAQLFILGCSWVLGIFQIGPVAGVMAYLFTIINSLQGAFIFLIHCLLNGQVR 852
+ AFA L +LG +W G+ I VMAYLFTI N+ QG FIF+ HC L +VR
Sbjct: 1020 IKSWVLGAFALLCLLGLTWSFGLLFINEETIVMAYLFTIFNAFQGVFIFIFHCALQKKVR 1079
Query: 853 EEY 855
+EY
Sbjct: 1080 KEY 1082
>gi|45433552 G protein-coupled receptor 133 [Homo sapiens]
Length = 874
Score = 203 bits (516), Expect = 7e-52
Identities = 116/321 (36%), Positives = 172/321 (53%), Gaps = 14/321 (4%)
Query: 560 GRWTSFGCVILEASETYTICSCNQMANLAVIMASGELTM----DFSLYIISHVGIIISLV 615
G W++ GC + + TY++C C + N A++M L + +L IS+VG +S++
Sbjct: 520 GVWSNHGCALTRGNLTYSVCRCTHLTNFAILMQVVPLELARGHQVALSSISYVGCSLSVL 579
Query: 616 CLVLAIATFLLCRS---IRNHNTYLHLHLCVCLLLAKTLFLAGIHKTDNKMGCAIIAGFL 672
CLV + TF + S IRN ++H +L +L+A+ L L C ++A L
Sbjct: 580 CLVATLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQVLLLISFRLEPGTTPCQVMAVLL 639
Query: 673 HYLFLACFFWMLVEAVILFLMVRNLKVVNYFSSRNIKMLHICAFGYGLPMLVVVISASVQ 732
HY FL+ F WMLVE + L+ MV + F S + K + G+G P+L+ +IS S
Sbjct: 640 HYFFLSAFAWMLVEGLHLYSMV-----IKVFGSEDSKHRYYYGMGWGFPLLICIISLSFA 694
Query: 733 PQGYGMHNRCWLNTETGFIWSFLGPVCTVIVINSLLLTWTLWILRQRLSSVNAEVSTLKD 792
YG N CWL+ +G IW+F+ P VIV+N +L ++ Q +S+ N ++
Sbjct: 695 MDSYGTSNNCWLSLASGAIWAFVAPALFVIVVNIGILIAVTRVISQ-ISADNYKIHGDPS 753
Query: 793 TRLLTFKAFAQLF-ILGCSWVLGIFQIGPVAGVMAYLFTIINSLQGAFIFLIHCLLNGQV 851
LT KA A L ILG SWV G+ + A V Y+F +NSLQG FIFL HCLLN +V
Sbjct: 754 AFKLTAKAVAVLLPILGTSWVFGVLAVNGCAVVFQYMFATLNSLQGLFIFLFHCLLNSEV 813
Query: 852 REEYKRWITGKTKPSSQSQTS 872
R +K + SS ++TS
Sbjct: 814 RAAFKHKTKVWSLTSSSARTS 834
>gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo
sapiens]
Length = 3014
Score = 189 bits (480), Expect = 1e-47
Identities = 107/338 (31%), Positives = 184/338 (54%), Gaps = 20/338 (5%)
Query: 547 RPICVSW--STDVKG-GRWTSFGCVILEASETYTICSCNQMANLAVIM-----ASGELTM 598
+P+CV W S V G G W++ GC +L + T+ C C+ A+ AV+M +GE+
Sbjct: 2408 KPVCVFWNHSLAVGGTGGWSARGCELLSRNRTHVACQCSHTASFAVLMDISRRENGEV-- 2465
Query: 599 DFSLYIISHVGIIISLVCLVLAIATFLLCRSIRNHNTYLHLHLCVCLLLAKTLFLAGIHK 658
L I+++ + +SL L++A L R +R++ +H HL V L L++ +F+ GI++
Sbjct: 2466 -LPLKIVTYAAVSLSLAALLVAFVLLSLVRMLRSNLHSIHKHLAVALFLSQLVFVIGINQ 2524
Query: 659 TDNKMGCAIIAGFLHYLFLACFFWMLVEAVILFLMVRNLKVVNYFSSRNIKMLHICAFGY 718
T+N C ++A LHY++++ F W LVE++ ++ M+ ++ ++ R ++ G+
Sbjct: 2525 TENPFLCTVVAILLHYIYMSTFAWTLVESLHVYRMLTEVRNIDTGPMRFYYVV-----GW 2579
Query: 719 GLPMLVVVISASVQPQGYGMHNRCWLNTETGFIWSFLGPVCTVIVINSLLLTWTLWILRQ 778
G+P +V ++ + PQGYG + CWL+ + IWSF GP+ VI+IN++ + + Q
Sbjct: 2580 GIPAIVTGLAVGLDPQGYGNPDFCWLSLQDTLIWSFAGPIGAVIIINTVTSVLSAKVSCQ 2639
Query: 779 RLSSVNAEVSTLKDTRLLTFKAFAQLFILGCSWVLGIFQIGPVAGVMAYLFTIINSLQGA 838
R + K L AF L ++ +W+LG+ + A YLF I + LQG
Sbjct: 2640 RKHHYYGK----KGIVSLLRTAFLLLLLISATWLLGLLAVNRDALSFHYLFAIFSGLQGP 2695
Query: 839 FIFLIHCLLNGQVREEYKRWITGKTKPSSQSQTSRILL 876
F+ L HC+LN +VR+ K + G+ S T+R L
Sbjct: 2696 FVLLFHCVLNQEVRKHLKGVLGGRKLHLEDSATTRATL 2733
Score = 45.4 bits (106), Expect = 2e-04
Identities = 40/178 (22%), Positives = 61/178 (34%), Gaps = 39/178 (21%)
Query: 132 DINECLTSSVCPEHSDCVNSMGSYSCSCQVGFISRN-------STCEDVDECADPRACPE 184
D+++ TSS CP +S C ++ YSC C G++ N + CE++ C P+
Sbjct: 1871 DVDDPCTSSPCPPNSRCHDAWEDYSCVCDKGYLGINCVDACHLNPCENMGACVRSPGSPQ 1930
Query: 185 HATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTEMCPINSTCTNTPGSYFC 244
C +Y +C ++ CP G C
Sbjct: 1931 GYVCECGPSHYGPYCE----------------------NKLDLPCPRGWWGNPVCGPCHC 1968
Query: 245 TCHPGFAP----SNGQLNFTDQGVECRDIDECRQDPSTCGPNS----ICTNALGSYSC 294
GF P +NGQ + + D C P C P+ C A G +C
Sbjct: 1969 AVSKGFDPDCNKTNGQCQCKENYYKLLAQDTCL--PCDCFPHGSHSRTCDMATGQCAC 2024
Score = 40.8 bits (94), Expect = 0.006
Identities = 31/118 (26%), Positives = 44/118 (37%), Gaps = 26/118 (22%)
Query: 51 VDSYYCACKQGFLSSNGQNHFKDPGVRCK-DIDECSQSPQPCGPNSSCKNLSGRYKCSCL 109
++ C C GF G C+ +ID C P CG N C++ G Y C C
Sbjct: 1344 INGLRCRCPPGFT-----------GDYCETEIDLCYSDP--CGANGRCRSREGGYTCECF 1390
Query: 110 DGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNSM-GSYSCSCQVGFISR 166
+ F+ + V + G + VC CVN + G + C C G R
Sbjct: 1391 EDFTGE--HCEVDARSGR---------CANGVCKNGGTCVNLLIGGFHCVCPPGEYER 1437
Score = 40.4 bits (93), Expect = 0.007
Identities = 30/105 (28%), Positives = 42/105 (40%), Gaps = 16/105 (15%)
Query: 149 VNSMGSYSCSCQVGFISRNSTCE-DVDEC-ADPRACPEHATCNNTVGNYSCFCNPGFESS 206
++ + C C GF CE ++D C +DP C + C + G Y+C C FE
Sbjct: 1341 IHPINGLRCRCPPGFTG--DYCETEIDLCYSDP--CGANGRCRSREGGYTCEC---FEDF 1393
Query: 207 SG-HLSFQGLKASCEDIDECTEMCPINSTCTN-TPGSYFCTCHPG 249
+G H C +C TC N G + C C PG
Sbjct: 1394 TGEHCEVDARSGRC-----ANGVCKNGGTCVNLLIGGFHCVCPPG 1433
Score = 38.9 bits (89), Expect = 0.021
Identities = 42/172 (24%), Positives = 60/172 (34%), Gaps = 29/172 (16%)
Query: 38 STLCPAYATCTNTVDSYYCACKQGFLSSNGQN--HFKDPGVRCKDIDECSQSP-QPCGPN 94
S+ CP + C + + Y C C +G+L N + H C+++ C +SP P G
Sbjct: 1878 SSPCPPNSRCHDAWEDYSCVCDKGYLGINCVDACHLNP----CENMGACVRSPGSPQGYV 1933
Query: 95 SSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNSMGS 154
C Y C + P W GN C + ++ P DC + G
Sbjct: 1934 CECG--PSHYGPYCENKLDLPCPRGWW----GNPVCGPCHCAVSKGFDP---DCNKTNGQ 1984
Query: 155 YSCSCQVGFISRNSTCEDVDECADPRACPEHA----TCNNTVGNYSCFCNPG 202
C + TC D C H TC+ G C C PG
Sbjct: 1985 CQCKENYYKLLAQDTCLPCD-------CFPHGSHSRTCDMATG--QCACKPG 2027
Score = 36.6 bits (83), Expect = 0.11
Identities = 31/117 (26%), Positives = 38/117 (32%), Gaps = 26/117 (22%)
Query: 192 VGNYSCFCNPGFESSSGHLSFQGLKASCE-DIDEC-TEMCPINSTCTNTPGSYFCTCHPG 249
+ C C PGF CE +ID C ++ C N C + G Y C C
Sbjct: 1344 INGLRCRCPPGFTGDY-----------CETEIDLCYSDPCGANGRCRSREGGYTCECFED 1392
Query: 250 FAPSNGQLNFTDQGVECR-DIDECRQDPSTCGPNSICTNAL-GSYSCGCIAGFHPNP 304
F G C D R C C N L G + C C G + P
Sbjct: 1393 FT-----------GEHCEVDARSGRCANGVCKNGGTCVNLLIGGFHCVCPPGEYERP 1438
Score = 30.8 bits (68), Expect = 5.8
Identities = 15/35 (42%), Positives = 17/35 (48%), Gaps = 2/35 (5%)
Query: 266 CRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGF 300
C D C P C PNS C +A YSC C G+
Sbjct: 1870 CDVDDPCTSSP--CPPNSRCHDAWEDYSCVCDKGY 1902
>gi|110347437 latent transforming growth factor beta binding protein
4 isoform c [Homo sapiens]
Length = 1557
Score = 188 bits (477), Expect = 2e-47
Identities = 108/301 (35%), Positives = 146/301 (48%), Gaps = 52/301 (17%)
Query: 27 KPNTKGNNCRDSTLCPAYATC-----TNTVDSYYC-ACKQGFLSSNGQNHFKDPGVRCKD 80
+PNT G+ C D C + C N+ S+ C C G G RC D
Sbjct: 717 QPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRG---------RCTD 767
Query: 81 IDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSS 140
+DECS PCGP+ C N G ++CSC G+ +P+ G+PG C D+NECL
Sbjct: 768 VDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPS------GRPG--PCADVNECLEGD 819
Query: 141 VCPEHSDCVNSMGSYSCSCQVGFI--SRNSTCEDVDECADPRACPEHATCNNTVGNYSCF 198
C H +C+N+ GS++C+C G+ R ++C DVDEC++ C + C NT G++ C
Sbjct: 820 FCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLC-QSGICTNTDGSFECI 878
Query: 199 CNPGFESSSGHLSFQGLKASCEDIDECTEMCPI---NSTCTNTPGSYFCT--CHPGF-AP 252
C PG + ASC D+DEC E P + C N+PGSY C C PG+ A
Sbjct: 879 CPPGHRAGPD-------LASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAG 931
Query: 253 SNGQLNFTDQGVECRDIDECRQ-DPSTCGPNSICTNALGSYSC--GCIAGFHPNPEGSQK 309
G C D+DEC++ P CG C N GSY C C G+ P P G +
Sbjct: 932 PEG---------TCDDVDECQEYGPEICGAQR-CENTPGSYRCTPACDPGYQPTPGGGCQ 981
Query: 310 D 310
D
Sbjct: 982 D 982
Score = 161 bits (407), Expect = 3e-39
Identities = 98/297 (32%), Positives = 134/297 (45%), Gaps = 66/297 (22%)
Query: 47 CTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKC 106
C NT S+ C C G+ ++ G C+D+DEC+QSP CG +CKNL G ++C
Sbjct: 578 CENTPGSFLCVCPAGYQAA-------PHGASCQDVDECTQSPGLCG-RGACKNLPGSFRC 629
Query: 107 SCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGFISR 166
C GF G+ D++EC C N+ GS+ C+C GF SR
Sbjct: 630 VCPAGFR------------GSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSR 677
Query: 167 N--STCEDVDECA-DPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDID 223
+ C+DVDECA P C + C NT G++ C C GF+ ++ + CED+D
Sbjct: 678 GPGAPCQDVDECARSPPPC-TYGRCENTEGSFQCVCPMGFQPNTA-------GSECEDVD 729
Query: 224 ECTE--MCPINSTCTNTPGSYFC-TCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCG 280
EC CP C N+PGS+ C TC G G+ C D+DEC CG
Sbjct: 730 ECENHLACP-GQECVNSPGSFQCRTCPSGHHLHRGR---------CTDVDECSSGAPPCG 779
Query: 281 PNSICTNALGSYSCGCIAGFH----------------------PNPEGSQKDGNFSC 315
P+ CTN GS+ C C G+ P+ E DG+F+C
Sbjct: 780 PHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFAC 836
Score = 157 bits (397), Expect = 4e-38
Identities = 103/329 (31%), Positives = 142/329 (43%), Gaps = 43/329 (13%)
Query: 17 SWEGHIRPTRKPNTKGNNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGV 76
+W G P P++ G R+ +C C + Y CAC GF S G
Sbjct: 466 AWTGPEIPESGPSS-GMCQRNPQVCGP-GRCISRPSGYTCACDSGFRLS-------PQGT 516
Query: 77 RCKDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINEC 136
RC D+DEC + P PC P C+N G ++C C GF + P C D++EC
Sbjct: 517 RCIDVDECRRVPPPCAPGR-CENSPGSFRCVCGPGFRAG---------PRAAECLDVDEC 566
Query: 137 LTSSVCPEHSDCVNSMGSYSCSCQVGFIS--RNSTCEDVDECADPRACPEHATCNNTVGN 194
+ C N+ GS+ C C G+ + ++C+DVDEC C N G+
Sbjct: 567 HRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGS 626
Query: 195 YSCFCNPGFESSSGHLSFQGLKASCEDIDECTEMCPI--NSTCTNTPGSYFCTCHPGFAP 252
+ C C GF S A ED+DEC + P C NT GS+ C C GF
Sbjct: 627 FRCVCPAGFRGS----------ACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFR- 675
Query: 253 SNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQKDGN 312
S G G C+D+DEC + P C C N GS+ C C GF PN GS+ +
Sbjct: 676 SRGP------GAPCQDVDECARSPPPCTYGR-CENTEGSFQCVCPMGFQPNTAGSECEDV 728
Query: 313 FSCQRVLFKCKEDVI--PDNKQIQQCQEG 339
C+ L ++ + P + Q + C G
Sbjct: 729 DECENHLACPGQECVNSPGSFQCRTCPSG 757
Score = 105 bits (262), Expect = 2e-22
Identities = 72/240 (30%), Positives = 105/240 (43%), Gaps = 45/240 (18%)
Query: 24 PTRKPNTKGNNCRDSTLCPAY-----ATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVR- 77
P +P +G +C D C CTNT S+ C C G H P +
Sbjct: 840 PGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPG--------HRAGPDLAS 891
Query: 78 CKDIDECSQ-SPQPCGPNSSCKNLSGRYKC--SCLDGF-SSPTGNDWVPGKPGNFSCTDI 133
C D+DEC + P CG + C+N G Y+C C G+ + P G +C D+
Sbjct: 892 CLDVDECRERGPALCG-SQRCENSPGSYRCVRDCDPGYHAGPEG-----------TCDDV 939
Query: 134 NECLT--SSVCPEHSDCVNSMGSYSCS--CQVGFI-SRNSTCEDVDECADPRACPEHATC 188
+EC +C C N+ GSY C+ C G+ + C+DVDEC + C HA C
Sbjct: 940 DECQEYGPEICGAQR-CENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVC 998
Query: 189 NNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTEMCPI--NSTCTNTPGSYFCTC 246
N G++ C C+ G+E + C D++EC + + + C N GS+ C C
Sbjct: 999 QNLPGSFQCLCDQGYEGARD-------GRHCVDVNECETLQGVCGAALCENVEGSFLCVC 1051
Score = 84.0 bits (206), Expect = 6e-16
Identities = 76/307 (24%), Positives = 111/307 (36%), Gaps = 77/307 (25%)
Query: 33 NNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCG 92
+ CR+ + C A+A C N S+ C C QG+ + H C D++EC CG
Sbjct: 984 DECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRH-------CVDVNECETLQGVCG 1036
Query: 93 PNSSCKNLSGRYKCSCLDG---FSSPTGN--------DWVPGKPGNFSCTDI-------- 133
+ C+N+ G + C C + F TG PG + +
Sbjct: 1037 A-ALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPP 1095
Query: 134 ------------------NECLTSSVCPEHSDCV--NSMGSYSCSCQVGFISRNSTCEDV 173
EC + P+ D + ++ C C VG S C +
Sbjct: 1096 PLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGE-GWGSGCR-I 1153
Query: 174 DECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECT----EMC 229
+C + C + G+ + SG LS + D+DEC ++C
Sbjct: 1154 QQCPGTETAEYQSLCPH---------GRGYLAPSGDLSLR------RDVDECQLFRDQVC 1198
Query: 230 PINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNAL 289
+ C NT Y C C SNG T Q +EC D DEC + C C N +
Sbjct: 1199 K-SGVCVNTAPGYSCYC------SNGYYYHT-QRLECIDNDECADEEPAC-EGGRCVNTV 1249
Query: 290 GSYSCGC 296
GSY C C
Sbjct: 1250 GSYHCTC 1256
Score = 57.0 bits (136), Expect = 8e-08
Identities = 30/74 (40%), Positives = 38/74 (51%), Gaps = 5/74 (6%)
Query: 132 DINEC--LTSSVCPEHSDCVNSMGSYSCSCQVGFI--SRNSTCEDVDECADPRACPEHAT 187
D++EC VC + CVN+ YSC C G+ ++ C D DECAD E
Sbjct: 1186 DVDECQLFRDQVC-KSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGR 1244
Query: 188 CNNTVGNYSCFCNP 201
C NTVG+Y C C P
Sbjct: 1245 CVNTVGSYHCTCEP 1258
Score = 52.8 bits (125), Expect = 1e-06
Identities = 28/79 (35%), Positives = 37/79 (46%), Gaps = 4/79 (5%)
Query: 133 INECLTSSVCPEHSDCVNSMGSYSCSCQVGFISRNSTCEDVDECADPRACPEHATCNNTV 192
+++C +C E + + C GF N +CEDVDECA C +H C NT
Sbjct: 254 VHDC---QLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGRC-QHGECANTR 309
Query: 193 GNYSCFCNPGFESSSGHLS 211
G Y+C C GF S S
Sbjct: 310 GGYTCVCPDGFLLDSSRSS 328
Score = 51.2 bits (121), Expect = 4e-06
Identities = 72/308 (23%), Positives = 108/308 (35%), Gaps = 54/308 (17%)
Query: 37 DSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSS 96
D LC + V + C GF NG C+D+DEC+ + C +
Sbjct: 256 DCQLCSERLGNSERVSAPDGPCPTGFERVNGS---------CEDVDECATGGR-C-QHGE 304
Query: 97 CKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPE-HSDCVNSMGSY 155
C N G Y C C DGF + + C++ V E C +
Sbjct: 305 CANTRGGYTCVCPDGFLLDSSR---------------SSCISQHVISEAKGPCFRVLRDG 349
Query: 156 SCSCQVGFISRNST-----CEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHL 210
CS I RN T C V + A R C + C PG+ S+ L
Sbjct: 350 GCSLP---ILRNITKQICCCSRVGK-AWGRGCQLCPPFGSEGFREICPAGPGYHYSASDL 405
Query: 211 SFQGLKASCEDIDECTEMCPINSTCTNTPGSYFCTCH-------PGFAPSNG-QLNFTD- 261
+ + ++ + P T+ P + F H P P G +L
Sbjct: 406 RY-NTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSI 464
Query: 262 ---QGVECRDIDE----CRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQKDGNFS 314
G E + C+++P CGP C + Y+C C +GF +P+G++
Sbjct: 465 PAWTGPEIPESGPSSGMCQRNPQVCGPGR-CISRPSGYTCACDSGFRLSPQGTRCIDVDE 523
Query: 315 CQRVLFKC 322
C+RV C
Sbjct: 524 CRRVPPPC 531
Score = 51.2 bits (121), Expect = 4e-06
Identities = 34/129 (26%), Positives = 51/129 (39%), Gaps = 19/129 (14%)
Query: 32 GNNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPC 91
G+ CR CP T C +G+L+ +G + +D+DEC
Sbjct: 1148 GSGCRIQQ-CPGTETAEY---QSLCPHGRGYLAPSGDLSLR------RDVDECQLFRDQV 1197
Query: 92 GPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNS 151
+ C N + Y C C +G+ T C D +EC E CVN+
Sbjct: 1198 CKSGVCVNTAPGYSCYCSNGYYYHTQR---------LECIDNDECADEEPACEGGRCVNT 1248
Query: 152 MGSYSCSCQ 160
+GSY C+C+
Sbjct: 1249 VGSYHCTCE 1257
Score = 50.8 bits (120), Expect = 5e-06
Identities = 46/176 (26%), Positives = 69/176 (39%), Gaps = 25/176 (14%)
Query: 88 PQPCGPNSSCKNLSG--RYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEH 145
P P GP + + G R+ + P G P PG + T PE
Sbjct: 1386 PPPPGPFARREAPYGAPRFDMPDFEDDGGPYGESEAPAPPGPGTRWPYRSRDTRRSFPEP 1445
Query: 146 SDCVNSMGSYSCSCQVGFISRNST-CEDVDECADPRACPEHATCNNTVGNYSCFCNPGFE 204
+ GSY+ S + + C +D C + R C ++C C G+
Sbjct: 1446 EEPPEG-GSYAGSLAEPYEELEAEECGILDGCTNGR-------CVRVPEGFTCRCFDGYR 1497
Query: 205 SSSGHLSFQGLKASCEDIDECTE------MCPINSTCTNTPGSYFCTCHPGFAPSN 254
++ C DI+EC E +C +N+ C NT GS+ C C PGFAP++
Sbjct: 1498 LDMTRMA-------CVDINECDEAEAASPLC-VNARCLNTDGSFRCICRPGFAPTH 1545
Score = 48.5 bits (114), Expect = 3e-05
Identities = 34/103 (33%), Positives = 50/103 (48%), Gaps = 15/103 (14%)
Query: 74 PGVRCKDIDECSQSPQPCGPNSSCKNLSGRY----KCSCLDGFSSPTGNDWVPGKPGNFS 129
PG+R +++ C + C+ S R + S DG PTG + V G S
Sbjct: 236 PGLRTQEV--CCRGAGLAWGVHDCQLCSERLGNSERVSAPDG-PCPTGFERVNG-----S 287
Query: 130 CTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGFI--SRNSTC 170
C D++EC T C +H +C N+ G Y+C C GF+ S S+C
Sbjct: 288 CEDVDECATGGRC-QHGECANTRGGYTCVCPDGFLLDSSRSSC 329
Score = 42.4 bits (98), Expect = 0.002
Identities = 28/87 (32%), Positives = 37/87 (42%), Gaps = 16/87 (18%)
Query: 219 CEDIDECTEMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPST 278
C +D CT N C P + C C G+ +L+ T C DI+EC +
Sbjct: 1470 CGILDGCT-----NGRCVRVPEGFTCRCFDGY-----RLDMTRMA--CVDINEC-DEAEA 1516
Query: 279 CGP---NSICTNALGSYSCGCIAGFHP 302
P N+ C N GS+ C C GF P
Sbjct: 1517 ASPLCVNARCLNTDGSFRCICRPGFAP 1543
Score = 37.4 bits (85), Expect = 0.062
Identities = 18/69 (26%), Positives = 31/69 (44%), Gaps = 9/69 (13%)
Query: 47 CTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDEC--SQSPQPCGPNSSCKNLSGRY 104
C + + C C G+ + + C DI+EC +++ P N+ C N G +
Sbjct: 1481 CVRVPEGFTCRCFDGYRLDMTR-------MACVDINECDEAEAASPLCVNARCLNTDGSF 1533
Query: 105 KCSCLDGFS 113
+C C GF+
Sbjct: 1534 RCICRPGFA 1542
Score = 33.9 bits (76), Expect = 0.69
Identities = 29/100 (29%), Positives = 35/100 (35%), Gaps = 15/100 (15%)
Query: 201 PGFESSSGHLSFQGLKASCEDIDECTEMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFT 260
PG + GL D C+E NS + P C GF NG
Sbjct: 236 PGLRTQEVCCRGAGLAWGVHDCQLCSERLG-NSERVSAPDG---PCPTGFERVNGS---- 287
Query: 261 DQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGF 300
C D+DEC C + C N G Y+C C GF
Sbjct: 288 -----CEDVDECATG-GRC-QHGECANTRGGYTCVCPDGF 320
>gi|110347412 latent transforming growth factor beta binding protein 4
isoform b [Homo sapiens]
Length = 1587
Score = 188 bits (477), Expect = 2e-47
Identities = 108/301 (35%), Positives = 146/301 (48%), Gaps = 52/301 (17%)
Query: 27 KPNTKGNNCRDSTLCPAYATC-----TNTVDSYYC-ACKQGFLSSNGQNHFKDPGVRCKD 80
+PNT G+ C D C + C N+ S+ C C G G RC D
Sbjct: 747 QPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRG---------RCTD 797
Query: 81 IDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSS 140
+DECS PCGP+ C N G ++CSC G+ +P+ G+PG C D+NECL
Sbjct: 798 VDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPS------GRPG--PCADVNECLEGD 849
Query: 141 VCPEHSDCVNSMGSYSCSCQVGFI--SRNSTCEDVDECADPRACPEHATCNNTVGNYSCF 198
C H +C+N+ GS++C+C G+ R ++C DVDEC++ C + C NT G++ C
Sbjct: 850 FCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLC-QSGICTNTDGSFECI 908
Query: 199 CNPGFESSSGHLSFQGLKASCEDIDECTEMCPI---NSTCTNTPGSYFCT--CHPGF-AP 252
C PG + ASC D+DEC E P + C N+PGSY C C PG+ A
Sbjct: 909 CPPGHRAGPD-------LASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAG 961
Query: 253 SNGQLNFTDQGVECRDIDECRQ-DPSTCGPNSICTNALGSYSC--GCIAGFHPNPEGSQK 309
G C D+DEC++ P CG C N GSY C C G+ P P G +
Sbjct: 962 PEG---------TCDDVDECQEYGPEICGAQR-CENTPGSYRCTPACDPGYQPTPGGGCQ 1011
Query: 310 D 310
D
Sbjct: 1012 D 1012
Score = 161 bits (407), Expect = 3e-39
Identities = 98/297 (32%), Positives = 134/297 (45%), Gaps = 66/297 (22%)
Query: 47 CTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKC 106
C NT S+ C C G+ ++ G C+D+DEC+QSP CG +CKNL G ++C
Sbjct: 608 CENTPGSFLCVCPAGYQAA-------PHGASCQDVDECTQSPGLCG-RGACKNLPGSFRC 659
Query: 107 SCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGFISR 166
C GF G+ D++EC C N+ GS+ C+C GF SR
Sbjct: 660 VCPAGFR------------GSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSR 707
Query: 167 N--STCEDVDECA-DPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDID 223
+ C+DVDECA P C + C NT G++ C C GF+ ++ + CED+D
Sbjct: 708 GPGAPCQDVDECARSPPPC-TYGRCENTEGSFQCVCPMGFQPNTA-------GSECEDVD 759
Query: 224 ECTE--MCPINSTCTNTPGSYFC-TCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCG 280
EC CP C N+PGS+ C TC G G+ C D+DEC CG
Sbjct: 760 ECENHLACP-GQECVNSPGSFQCRTCPSGHHLHRGR---------CTDVDECSSGAPPCG 809
Query: 281 PNSICTNALGSYSCGCIAGFH----------------------PNPEGSQKDGNFSC 315
P+ CTN GS+ C C G+ P+ E DG+F+C
Sbjct: 810 PHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFAC 866
Score = 157 bits (397), Expect = 4e-38
Identities = 103/329 (31%), Positives = 142/329 (43%), Gaps = 43/329 (13%)
Query: 17 SWEGHIRPTRKPNTKGNNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGV 76
+W G P P++ G R+ +C C + Y CAC GF S G
Sbjct: 496 AWTGPEIPESGPSS-GMCQRNPQVCGP-GRCISRPSGYTCACDSGFRLS-------PQGT 546
Query: 77 RCKDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINEC 136
RC D+DEC + P PC P C+N G ++C C GF + P C D++EC
Sbjct: 547 RCIDVDECRRVPPPCAPGR-CENSPGSFRCVCGPGFRAG---------PRAAECLDVDEC 596
Query: 137 LTSSVCPEHSDCVNSMGSYSCSCQVGFIS--RNSTCEDVDECADPRACPEHATCNNTVGN 194
+ C N+ GS+ C C G+ + ++C+DVDEC C N G+
Sbjct: 597 HRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGS 656
Query: 195 YSCFCNPGFESSSGHLSFQGLKASCEDIDECTEMCPI--NSTCTNTPGSYFCTCHPGFAP 252
+ C C GF S A ED+DEC + P C NT GS+ C C GF
Sbjct: 657 FRCVCPAGFRGS----------ACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFR- 705
Query: 253 SNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQKDGN 312
S G G C+D+DEC + P C C N GS+ C C GF PN GS+ +
Sbjct: 706 SRGP------GAPCQDVDECARSPPPCTYGR-CENTEGSFQCVCPMGFQPNTAGSECEDV 758
Query: 313 FSCQRVLFKCKEDVI--PDNKQIQQCQEG 339
C+ L ++ + P + Q + C G
Sbjct: 759 DECENHLACPGQECVNSPGSFQCRTCPSG 787
Score = 105 bits (262), Expect = 2e-22
Identities = 72/240 (30%), Positives = 105/240 (43%), Gaps = 45/240 (18%)
Query: 24 PTRKPNTKGNNCRDSTLCPAY-----ATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVR- 77
P +P +G +C D C CTNT S+ C C G H P +
Sbjct: 870 PGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPG--------HRAGPDLAS 921
Query: 78 CKDIDECSQ-SPQPCGPNSSCKNLSGRYKC--SCLDGF-SSPTGNDWVPGKPGNFSCTDI 133
C D+DEC + P CG + C+N G Y+C C G+ + P G +C D+
Sbjct: 922 CLDVDECRERGPALCG-SQRCENSPGSYRCVRDCDPGYHAGPEG-----------TCDDV 969
Query: 134 NECLT--SSVCPEHSDCVNSMGSYSCS--CQVGFI-SRNSTCEDVDECADPRACPEHATC 188
+EC +C C N+ GSY C+ C G+ + C+DVDEC + C HA C
Sbjct: 970 DECQEYGPEICGAQR-CENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVC 1028
Query: 189 NNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTEMCPI--NSTCTNTPGSYFCTC 246
N G++ C C+ G+E + C D++EC + + + C N GS+ C C
Sbjct: 1029 QNLPGSFQCLCDQGYEGARD-------GRHCVDVNECETLQGVCGAALCENVEGSFLCVC 1081
Score = 84.0 bits (206), Expect = 6e-16
Identities = 76/307 (24%), Positives = 111/307 (36%), Gaps = 77/307 (25%)
Query: 33 NNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCG 92
+ CR+ + C A+A C N S+ C C QG+ + H C D++EC CG
Sbjct: 1014 DECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRH-------CVDVNECETLQGVCG 1066
Query: 93 PNSSCKNLSGRYKCSCLDG---FSSPTGN--------DWVPGKPGNFSCTDI-------- 133
+ C+N+ G + C C + F TG PG + +
Sbjct: 1067 A-ALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPP 1125
Query: 134 ------------------NECLTSSVCPEHSDCV--NSMGSYSCSCQVGFISRNSTCEDV 173
EC + P+ D + ++ C C VG S C +
Sbjct: 1126 PLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGE-GWGSGCR-I 1183
Query: 174 DECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECT----EMC 229
+C + C + G+ + SG LS + D+DEC ++C
Sbjct: 1184 QQCPGTETAEYQSLCPH---------GRGYLAPSGDLSLR------RDVDECQLFRDQVC 1228
Query: 230 PINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNAL 289
+ C NT Y C C SNG T Q +EC D DEC + C C N +
Sbjct: 1229 K-SGVCVNTAPGYSCYC------SNGYYYHT-QRLECIDNDECADEEPAC-EGGRCVNTV 1279
Query: 290 GSYSCGC 296
GSY C C
Sbjct: 1280 GSYHCTC 1286
Score = 57.0 bits (136), Expect = 8e-08
Identities = 30/74 (40%), Positives = 38/74 (51%), Gaps = 5/74 (6%)
Query: 132 DINEC--LTSSVCPEHSDCVNSMGSYSCSCQVGFI--SRNSTCEDVDECADPRACPEHAT 187
D++EC VC + CVN+ YSC C G+ ++ C D DECAD E
Sbjct: 1216 DVDECQLFRDQVC-KSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGR 1274
Query: 188 CNNTVGNYSCFCNP 201
C NTVG+Y C C P
Sbjct: 1275 CVNTVGSYHCTCEP 1288
Score = 52.8 bits (125), Expect = 1e-06
Identities = 28/79 (35%), Positives = 37/79 (46%), Gaps = 4/79 (5%)
Query: 133 INECLTSSVCPEHSDCVNSMGSYSCSCQVGFISRNSTCEDVDECADPRACPEHATCNNTV 192
+++C +C E + + C GF N +CEDVDECA C +H C NT
Sbjct: 284 VHDC---QLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGRC-QHGECANTR 339
Query: 193 GNYSCFCNPGFESSSGHLS 211
G Y+C C GF S S
Sbjct: 340 GGYTCVCPDGFLLDSSRSS 358
Score = 51.2 bits (121), Expect = 4e-06
Identities = 72/308 (23%), Positives = 108/308 (35%), Gaps = 54/308 (17%)
Query: 37 DSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSS 96
D LC + V + C GF NG C+D+DEC+ + C +
Sbjct: 286 DCQLCSERLGNSERVSAPDGPCPTGFERVNGS---------CEDVDECATGGR-C-QHGE 334
Query: 97 CKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPE-HSDCVNSMGSY 155
C N G Y C C DGF + + C++ V E C +
Sbjct: 335 CANTRGGYTCVCPDGFLLDSSR---------------SSCISQHVISEAKGPCFRVLRDG 379
Query: 156 SCSCQVGFISRNST-----CEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHL 210
CS I RN T C V + A R C + C PG+ S+ L
Sbjct: 380 GCSLP---ILRNITKQICCCSRVGK-AWGRGCQLCPPFGSEGFREICPAGPGYHYSASDL 435
Query: 211 SFQGLKASCEDIDECTEMCPINSTCTNTPGSYFCTCH-------PGFAPSNG-QLNFTD- 261
+ + ++ + P T+ P + F H P P G +L
Sbjct: 436 RY-NTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSI 494
Query: 262 ---QGVECRDIDE----CRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQKDGNFS 314
G E + C+++P CGP C + Y+C C +GF +P+G++
Sbjct: 495 PAWTGPEIPESGPSSGMCQRNPQVCGPGR-CISRPSGYTCACDSGFRLSPQGTRCIDVDE 553
Query: 315 CQRVLFKC 322
C+RV C
Sbjct: 554 CRRVPPPC 561
Score = 51.2 bits (121), Expect = 4e-06
Identities = 34/129 (26%), Positives = 51/129 (39%), Gaps = 19/129 (14%)
Query: 32 GNNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPC 91
G+ CR CP T C +G+L+ +G + +D+DEC
Sbjct: 1178 GSGCRIQQ-CPGTETAEY---QSLCPHGRGYLAPSGDLSLR------RDVDECQLFRDQV 1227
Query: 92 GPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNS 151
+ C N + Y C C +G+ T C D +EC E CVN+
Sbjct: 1228 CKSGVCVNTAPGYSCYCSNGYYYHTQR---------LECIDNDECADEEPACEGGRCVNT 1278
Query: 152 MGSYSCSCQ 160
+GSY C+C+
Sbjct: 1279 VGSYHCTCE 1287
Score = 50.8 bits (120), Expect = 5e-06
Identities = 46/176 (26%), Positives = 69/176 (39%), Gaps = 25/176 (14%)
Query: 88 PQPCGPNSSCKNLSG--RYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEH 145
P P GP + + G R+ + P G P PG + T PE
Sbjct: 1416 PPPPGPFARREAPYGAPRFDMPDFEDDGGPYGESEAPAPPGPGTRWPYRSRDTRRSFPEP 1475
Query: 146 SDCVNSMGSYSCSCQVGFISRNST-CEDVDECADPRACPEHATCNNTVGNYSCFCNPGFE 204
+ GSY+ S + + C +D C + R C ++C C G+
Sbjct: 1476 EEPPEG-GSYAGSLAEPYEELEAEECGILDGCTNGR-------CVRVPEGFTCRCFDGYR 1527
Query: 205 SSSGHLSFQGLKASCEDIDECTE------MCPINSTCTNTPGSYFCTCHPGFAPSN 254
++ C DI+EC E +C +N+ C NT GS+ C C PGFAP++
Sbjct: 1528 LDMTRMA-------CVDINECDEAEAASPLC-VNARCLNTDGSFRCICRPGFAPTH 1575
Score = 48.5 bits (114), Expect = 3e-05
Identities = 34/103 (33%), Positives = 50/103 (48%), Gaps = 15/103 (14%)
Query: 74 PGVRCKDIDECSQSPQPCGPNSSCKNLSGRY----KCSCLDGFSSPTGNDWVPGKPGNFS 129
PG+R +++ C + C+ S R + S DG PTG + V G S
Sbjct: 266 PGLRTQEV--CCRGAGLAWGVHDCQLCSERLGNSERVSAPDG-PCPTGFERVNG-----S 317
Query: 130 CTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGFI--SRNSTC 170
C D++EC T C +H +C N+ G Y+C C GF+ S S+C
Sbjct: 318 CEDVDECATGGRC-QHGECANTRGGYTCVCPDGFLLDSSRSSC 359
Score = 42.4 bits (98), Expect = 0.002
Identities = 28/87 (32%), Positives = 37/87 (42%), Gaps = 16/87 (18%)
Query: 219 CEDIDECTEMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPST 278
C +D CT N C P + C C G+ +L+ T C DI+EC +
Sbjct: 1500 CGILDGCT-----NGRCVRVPEGFTCRCFDGY-----RLDMTRMA--CVDINEC-DEAEA 1546
Query: 279 CGP---NSICTNALGSYSCGCIAGFHP 302
P N+ C N GS+ C C GF P
Sbjct: 1547 ASPLCVNARCLNTDGSFRCICRPGFAP 1573
Score = 37.4 bits (85), Expect = 0.062
Identities = 18/69 (26%), Positives = 31/69 (44%), Gaps = 9/69 (13%)
Query: 47 CTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDEC--SQSPQPCGPNSSCKNLSGRY 104
C + + C C G+ + + C DI+EC +++ P N+ C N G +
Sbjct: 1511 CVRVPEGFTCRCFDGYRLDMTR-------MACVDINECDEAEAASPLCVNARCLNTDGSF 1563
Query: 105 KCSCLDGFS 113
+C C GF+
Sbjct: 1564 RCICRPGFA 1572
Score = 33.9 bits (76), Expect = 0.69
Identities = 29/100 (29%), Positives = 35/100 (35%), Gaps = 15/100 (15%)
Query: 201 PGFESSSGHLSFQGLKASCEDIDECTEMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFT 260
PG + GL D C+E NS + P C GF NG
Sbjct: 266 PGLRTQEVCCRGAGLAWGVHDCQLCSERLG-NSERVSAPDG---PCPTGFERVNGS---- 317
Query: 261 DQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGF 300
C D+DEC C + C N G Y+C C GF
Sbjct: 318 -----CEDVDECATG-GRC-QHGECANTRGGYTCVCPDGF 350
>gi|110347431 latent transforming growth factor beta binding protein 4
isoform a [Homo sapiens]
Length = 1624
Score = 188 bits (477), Expect = 2e-47
Identities = 108/301 (35%), Positives = 146/301 (48%), Gaps = 52/301 (17%)
Query: 27 KPNTKGNNCRDSTLCPAYATC-----TNTVDSYYC-ACKQGFLSSNGQNHFKDPGVRCKD 80
+PNT G+ C D C + C N+ S+ C C G G RC D
Sbjct: 784 QPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRG---------RCTD 834
Query: 81 IDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSS 140
+DECS PCGP+ C N G ++CSC G+ +P+ G+PG C D+NECL
Sbjct: 835 VDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPS------GRPG--PCADVNECLEGD 886
Query: 141 VCPEHSDCVNSMGSYSCSCQVGFI--SRNSTCEDVDECADPRACPEHATCNNTVGNYSCF 198
C H +C+N+ GS++C+C G+ R ++C DVDEC++ C + C NT G++ C
Sbjct: 887 FCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLC-QSGICTNTDGSFECI 945
Query: 199 CNPGFESSSGHLSFQGLKASCEDIDECTEMCPI---NSTCTNTPGSYFCT--CHPGF-AP 252
C PG + ASC D+DEC E P + C N+PGSY C C PG+ A
Sbjct: 946 CPPGHRAGPD-------LASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAG 998
Query: 253 SNGQLNFTDQGVECRDIDECRQ-DPSTCGPNSICTNALGSYSC--GCIAGFHPNPEGSQK 309
G C D+DEC++ P CG C N GSY C C G+ P P G +
Sbjct: 999 PEG---------TCDDVDECQEYGPEICGAQR-CENTPGSYRCTPACDPGYQPTPGGGCQ 1048
Query: 310 D 310
D
Sbjct: 1049 D 1049
Score = 161 bits (407), Expect = 3e-39
Identities = 98/297 (32%), Positives = 134/297 (45%), Gaps = 66/297 (22%)
Query: 47 CTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKC 106
C NT S+ C C G+ ++ G C+D+DEC+QSP CG +CKNL G ++C
Sbjct: 645 CENTPGSFLCVCPAGYQAA-------PHGASCQDVDECTQSPGLCG-RGACKNLPGSFRC 696
Query: 107 SCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGFISR 166
C GF G+ D++EC C N+ GS+ C+C GF SR
Sbjct: 697 VCPAGFR------------GSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSR 744
Query: 167 N--STCEDVDECA-DPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDID 223
+ C+DVDECA P C + C NT G++ C C GF+ ++ + CED+D
Sbjct: 745 GPGAPCQDVDECARSPPPC-TYGRCENTEGSFQCVCPMGFQPNTA-------GSECEDVD 796
Query: 224 ECTE--MCPINSTCTNTPGSYFC-TCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCG 280
EC CP C N+PGS+ C TC G G+ C D+DEC CG
Sbjct: 797 ECENHLACP-GQECVNSPGSFQCRTCPSGHHLHRGR---------CTDVDECSSGAPPCG 846
Query: 281 PNSICTNALGSYSCGCIAGFH----------------------PNPEGSQKDGNFSC 315
P+ CTN GS+ C C G+ P+ E DG+F+C
Sbjct: 847 PHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFAC 903
Score = 157 bits (397), Expect = 4e-38
Identities = 103/329 (31%), Positives = 142/329 (43%), Gaps = 43/329 (13%)
Query: 17 SWEGHIRPTRKPNTKGNNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGV 76
+W G P P++ G R+ +C C + Y CAC GF S G
Sbjct: 533 AWTGPEIPESGPSS-GMCQRNPQVCGP-GRCISRPSGYTCACDSGFRLS-------PQGT 583
Query: 77 RCKDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINEC 136
RC D+DEC + P PC P C+N G ++C C GF + P C D++EC
Sbjct: 584 RCIDVDECRRVPPPCAPGR-CENSPGSFRCVCGPGFRAG---------PRAAECLDVDEC 633
Query: 137 LTSSVCPEHSDCVNSMGSYSCSCQVGFIS--RNSTCEDVDECADPRACPEHATCNNTVGN 194
+ C N+ GS+ C C G+ + ++C+DVDEC C N G+
Sbjct: 634 HRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGS 693
Query: 195 YSCFCNPGFESSSGHLSFQGLKASCEDIDECTEMCPI--NSTCTNTPGSYFCTCHPGFAP 252
+ C C GF S A ED+DEC + P C NT GS+ C C GF
Sbjct: 694 FRCVCPAGFRGS----------ACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFR- 742
Query: 253 SNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQKDGN 312
S G G C+D+DEC + P C C N GS+ C C GF PN GS+ +
Sbjct: 743 SRGP------GAPCQDVDECARSPPPCTYGR-CENTEGSFQCVCPMGFQPNTAGSECEDV 795
Query: 313 FSCQRVLFKCKEDVI--PDNKQIQQCQEG 339
C+ L ++ + P + Q + C G
Sbjct: 796 DECENHLACPGQECVNSPGSFQCRTCPSG 824
Score = 105 bits (262), Expect = 2e-22
Identities = 72/240 (30%), Positives = 105/240 (43%), Gaps = 45/240 (18%)
Query: 24 PTRKPNTKGNNCRDSTLCPAY-----ATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVR- 77
P +P +G +C D C CTNT S+ C C G H P +
Sbjct: 907 PGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPG--------HRAGPDLAS 958
Query: 78 CKDIDECSQ-SPQPCGPNSSCKNLSGRYKC--SCLDGF-SSPTGNDWVPGKPGNFSCTDI 133
C D+DEC + P CG + C+N G Y+C C G+ + P G +C D+
Sbjct: 959 CLDVDECRERGPALCG-SQRCENSPGSYRCVRDCDPGYHAGPEG-----------TCDDV 1006
Query: 134 NECLT--SSVCPEHSDCVNSMGSYSCS--CQVGFI-SRNSTCEDVDECADPRACPEHATC 188
+EC +C C N+ GSY C+ C G+ + C+DVDEC + C HA C
Sbjct: 1007 DECQEYGPEICGAQR-CENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVC 1065
Query: 189 NNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTEMCPI--NSTCTNTPGSYFCTC 246
N G++ C C+ G+E + C D++EC + + + C N GS+ C C
Sbjct: 1066 QNLPGSFQCLCDQGYEGARD-------GRHCVDVNECETLQGVCGAALCENVEGSFLCVC 1118
Score = 84.0 bits (206), Expect = 6e-16
Identities = 76/307 (24%), Positives = 111/307 (36%), Gaps = 77/307 (25%)
Query: 33 NNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCG 92
+ CR+ + C A+A C N S+ C C QG+ + H C D++EC CG
Sbjct: 1051 DECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRH-------CVDVNECETLQGVCG 1103
Query: 93 PNSSCKNLSGRYKCSCLDG---FSSPTGN--------DWVPGKPGNFSCTDI-------- 133
+ C+N+ G + C C + F TG PG + +
Sbjct: 1104 A-ALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPP 1162
Query: 134 ------------------NECLTSSVCPEHSDCV--NSMGSYSCSCQVGFISRNSTCEDV 173
EC + P+ D + ++ C C VG S C +
Sbjct: 1163 PLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGE-GWGSGCR-I 1220
Query: 174 DECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECT----EMC 229
+C + C + G+ + SG LS + D+DEC ++C
Sbjct: 1221 QQCPGTETAEYQSLCPH---------GRGYLAPSGDLSLR------RDVDECQLFRDQVC 1265
Query: 230 PINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNAL 289
+ C NT Y C C SNG T Q +EC D DEC + C C N +
Sbjct: 1266 K-SGVCVNTAPGYSCYC------SNGYYYHT-QRLECIDNDECADEEPAC-EGGRCVNTV 1316
Query: 290 GSYSCGC 296
GSY C C
Sbjct: 1317 GSYHCTC 1323
Score = 57.0 bits (136), Expect = 8e-08
Identities = 30/74 (40%), Positives = 38/74 (51%), Gaps = 5/74 (6%)
Query: 132 DINEC--LTSSVCPEHSDCVNSMGSYSCSCQVGFI--SRNSTCEDVDECADPRACPEHAT 187
D++EC VC + CVN+ YSC C G+ ++ C D DECAD E
Sbjct: 1253 DVDECQLFRDQVC-KSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGR 1311
Query: 188 CNNTVGNYSCFCNP 201
C NTVG+Y C C P
Sbjct: 1312 CVNTVGSYHCTCEP 1325
Score = 52.8 bits (125), Expect = 1e-06
Identities = 28/79 (35%), Positives = 37/79 (46%), Gaps = 4/79 (5%)
Query: 133 INECLTSSVCPEHSDCVNSMGSYSCSCQVGFISRNSTCEDVDECADPRACPEHATCNNTV 192
+++C +C E + + C GF N +CEDVDECA C +H C NT
Sbjct: 321 VHDC---QLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGRC-QHGECANTR 376
Query: 193 GNYSCFCNPGFESSSGHLS 211
G Y+C C GF S S
Sbjct: 377 GGYTCVCPDGFLLDSSRSS 395
Score = 51.2 bits (121), Expect = 4e-06
Identities = 72/308 (23%), Positives = 108/308 (35%), Gaps = 54/308 (17%)
Query: 37 DSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSS 96
D LC + V + C GF NG C+D+DEC+ + C +
Sbjct: 323 DCQLCSERLGNSERVSAPDGPCPTGFERVNGS---------CEDVDECATGGR-C-QHGE 371
Query: 97 CKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPE-HSDCVNSMGSY 155
C N G Y C C DGF + + C++ V E C +
Sbjct: 372 CANTRGGYTCVCPDGFLLDSSR---------------SSCISQHVISEAKGPCFRVLRDG 416
Query: 156 SCSCQVGFISRNST-----CEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHL 210
CS I RN T C V + A R C + C PG+ S+ L
Sbjct: 417 GCSLP---ILRNITKQICCCSRVGK-AWGRGCQLCPPFGSEGFREICPAGPGYHYSASDL 472
Query: 211 SFQGLKASCEDIDECTEMCPINSTCTNTPGSYFCTCH-------PGFAPSNG-QLNFTD- 261
+ + ++ + P T+ P + F H P P G +L
Sbjct: 473 RY-NTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSI 531
Query: 262 ---QGVECRDIDE----CRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQKDGNFS 314
G E + C+++P CGP C + Y+C C +GF +P+G++
Sbjct: 532 PAWTGPEIPESGPSSGMCQRNPQVCGPGR-CISRPSGYTCACDSGFRLSPQGTRCIDVDE 590
Query: 315 CQRVLFKC 322
C+RV C
Sbjct: 591 CRRVPPPC 598
Score = 51.2 bits (121), Expect = 4e-06
Identities = 34/129 (26%), Positives = 51/129 (39%), Gaps = 19/129 (14%)
Query: 32 GNNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPC 91
G+ CR CP T C +G+L+ +G + +D+DEC
Sbjct: 1215 GSGCRIQQ-CPGTETAEY---QSLCPHGRGYLAPSGDLSLR------RDVDECQLFRDQV 1264
Query: 92 GPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNS 151
+ C N + Y C C +G+ T C D +EC E CVN+
Sbjct: 1265 CKSGVCVNTAPGYSCYCSNGYYYHTQR---------LECIDNDECADEEPACEGGRCVNT 1315
Query: 152 MGSYSCSCQ 160
+GSY C+C+
Sbjct: 1316 VGSYHCTCE 1324
Score = 50.8 bits (120), Expect = 5e-06
Identities = 46/176 (26%), Positives = 69/176 (39%), Gaps = 25/176 (14%)
Query: 88 PQPCGPNSSCKNLSG--RYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEH 145
P P GP + + G R+ + P G P PG + T PE
Sbjct: 1453 PPPPGPFARREAPYGAPRFDMPDFEDDGGPYGESEAPAPPGPGTRWPYRSRDTRRSFPEP 1512
Query: 146 SDCVNSMGSYSCSCQVGFISRNST-CEDVDECADPRACPEHATCNNTVGNYSCFCNPGFE 204
+ GSY+ S + + C +D C + R C ++C C G+
Sbjct: 1513 EEPPEG-GSYAGSLAEPYEELEAEECGILDGCTNGR-------CVRVPEGFTCRCFDGYR 1564
Query: 205 SSSGHLSFQGLKASCEDIDECTE------MCPINSTCTNTPGSYFCTCHPGFAPSN 254
++ C DI+EC E +C +N+ C NT GS+ C C PGFAP++
Sbjct: 1565 LDMTRMA-------CVDINECDEAEAASPLC-VNARCLNTDGSFRCICRPGFAPTH 1612
Score = 48.5 bits (114), Expect = 3e-05
Identities = 34/103 (33%), Positives = 50/103 (48%), Gaps = 15/103 (14%)
Query: 74 PGVRCKDIDECSQSPQPCGPNSSCKNLSGRY----KCSCLDGFSSPTGNDWVPGKPGNFS 129
PG+R +++ C + C+ S R + S DG PTG + V G S
Sbjct: 303 PGLRTQEV--CCRGAGLAWGVHDCQLCSERLGNSERVSAPDG-PCPTGFERVNG-----S 354
Query: 130 CTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGFI--SRNSTC 170
C D++EC T C +H +C N+ G Y+C C GF+ S S+C
Sbjct: 355 CEDVDECATGGRC-QHGECANTRGGYTCVCPDGFLLDSSRSSC 396
Score = 42.4 bits (98), Expect = 0.002
Identities = 28/87 (32%), Positives = 37/87 (42%), Gaps = 16/87 (18%)
Query: 219 CEDIDECTEMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPST 278
C +D CT N C P + C C G+ +L+ T C DI+EC +
Sbjct: 1537 CGILDGCT-----NGRCVRVPEGFTCRCFDGY-----RLDMTRMA--CVDINEC-DEAEA 1583
Query: 279 CGP---NSICTNALGSYSCGCIAGFHP 302
P N+ C N GS+ C C GF P
Sbjct: 1584 ASPLCVNARCLNTDGSFRCICRPGFAP 1610
Score = 37.4 bits (85), Expect = 0.062
Identities = 18/69 (26%), Positives = 31/69 (44%), Gaps = 9/69 (13%)
Query: 47 CTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDEC--SQSPQPCGPNSSCKNLSGRY 104
C + + C C G+ + + C DI+EC +++ P N+ C N G +
Sbjct: 1548 CVRVPEGFTCRCFDGYRLDMTR-------MACVDINECDEAEAASPLCVNARCLNTDGSF 1600
Query: 105 KCSCLDGFS 113
+C C GF+
Sbjct: 1601 RCICRPGFA 1609
Score = 33.9 bits (76), Expect = 0.69
Identities = 29/100 (29%), Positives = 35/100 (35%), Gaps = 15/100 (15%)
Query: 201 PGFESSSGHLSFQGLKASCEDIDECTEMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFT 260
PG + GL D C+E NS + P C GF NG
Sbjct: 303 PGLRTQEVCCRGAGLAWGVHDCQLCSERLG-NSERVSAPDG---PCPTGFERVNGS---- 354
Query: 261 DQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGF 300
C D+DEC C + C N G Y+C C GF
Sbjct: 355 -----CEDVDECATG-GRC-QHGECANTRGGYTCVCPDGF 387
>gi|194328809 latent transforming growth factor beta binding protein
3 isoform 1 [Homo sapiens]
Length = 1303
Score = 174 bits (442), Expect = 2e-43
Identities = 100/300 (33%), Positives = 141/300 (47%), Gaps = 42/300 (14%)
Query: 22 IRPTRKPNTKGNNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDI 81
I PT+ T + CR + + C Y C C G+ S+ Q+ + C D+
Sbjct: 567 IAPTQVTET--DECRLNQNICGHGECVPGPPDYSCHCNPGY-RSHPQHRY------CVDV 617
Query: 82 DECSQSPQPCGPNSS-CKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSS 140
+EC +PCGP C N G Y C C G+ G G SC D+NEC
Sbjct: 618 NECEA--EPCGPGRGICMNTGGSYNCHCNRGYRLHVG-------AGGRSCVDLNECAKPH 668
Query: 141 VCPEHSDCVNSMGSYSCSCQVGF---ISRNSTCEDVDECADPRACPEHATCNNTVGNYSC 197
+C + C+N G Y C+C G+ SR CED+DEC DP +CP+ C N G++ C
Sbjct: 669 LCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPD-GKCENKPGSFKC 727
Query: 198 F-CNPGFESSSGHLSFQGLKASCEDIDECTEMCPIN-STCTNTPGSYFCTCHPGFAPSNG 255
C PG+ S G +C D++EC E P + C N PGS+ CTC G+AP+
Sbjct: 728 IACQPGYRSQGG--------GACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPA-- 777
Query: 256 QLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQKDGNFSC 315
G C D+DEC + N IC+N GS+ C C++G+H + + S + C
Sbjct: 778 -----PDGRSCLDVDEC--EAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDEC 830
Score = 115 bits (289), Expect = 1e-25
Identities = 103/365 (28%), Positives = 140/365 (38%), Gaps = 94/365 (25%)
Query: 28 PNTKGNNCRDSTLCPA-----YATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDID 82
P G +C D C A C+NT S+ C C G+ S ++H C+DID
Sbjct: 776 PAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSH-------CEDID 828
Query: 83 ECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTS-SV 141
EC P C C N +G Y+C C P G+ V G+ C DI+EC S+
Sbjct: 829 EC-DFPAAC-IGGDCINTNGSYRCLC------PQGHRLVGGR----KCQDIDECSQDPSL 876
Query: 142 CPEHSDCVNSMGSYSCSCQVGFISRNST--CEDVDECADPRAC----PEHATCNN----T 191
C H C N GSY C C GF CE+V++ + C + C++
Sbjct: 877 CLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATN 936
Query: 192 VGNYSCFCN--------------PGFESSSGH--------------LSFQGLKASCEDID 223
V C C+ P + S+ H + G+ A DID
Sbjct: 937 VTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAH-RDID 995
Query: 224 EC----TEMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTC 279
EC +E+C C NT Y C C GF +G L +EC D+DEC D S C
Sbjct: 996 ECMLFGSEICK-EGKCVNTQPGYECYCKQGFY-YDGNL------LECVDVDEC-LDESNC 1046
Query: 280 GPNSICTNALGSYSCGCIAGFHPNPEGSQKDGNFSCQRVLFKCKEDVIPDNKQIQQCQEG 339
N +C N G Y C C P C + P+ + +CQ+
Sbjct: 1047 -RNGVCENTRGGYRCAC------TPPAEYSPAQRQC----------LSPEEMDVDECQDP 1089
Query: 340 TAVKP 344
A +P
Sbjct: 1090 AACRP 1094
Score = 101 bits (251), Expect = 4e-21
Identities = 78/250 (31%), Positives = 101/250 (40%), Gaps = 40/250 (16%)
Query: 36 RDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQN--------HFK-------DPGVRCKD 80
+D +LC + C N SY C C +GF + Q+ H K D V C
Sbjct: 872 QDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDS 931
Query: 81 IDECSQSPQPC------GPNSSCKNL------SGRYKCSCLDGFSSPTGNDWVP-GKPGN 127
+ + + Q C G C+ S + C DG N+ V G P +
Sbjct: 932 VLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAH 991
Query: 128 FSCTDINECLT--SSVCPEHSDCVNSMGSYSCSCQVGFISRNST--CEDVDECADPRACP 183
DI+EC+ S +C E CVN+ Y C C+ GF + C DVDEC D C
Sbjct: 992 ---RDIDECMLFGSEICKE-GKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNC- 1046
Query: 184 EHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTEMCPIN-STCTNTPGSY 242
+ C NT G Y C C P E S Q L D+DEC + C N PGSY
Sbjct: 1047 RNGVCENTRGGYRCACTPPAEYSPAQR--QCLSPEEMDVDECQDPAACRPGRCVNLPGSY 1104
Query: 243 FCTCHPGFAP 252
C C P + P
Sbjct: 1105 RCECRPPWVP 1114
Score = 81.3 bits (199), Expect = 4e-15
Identities = 102/365 (27%), Positives = 132/365 (36%), Gaps = 96/365 (26%)
Query: 12 CCVMHSWEGH-IRPTRKPNTKGNNC--------RDSTLCPAYAT-------CTNTVDSYY 55
C V S E H + P K T+ NN RD C + + C NT Y
Sbjct: 959 CPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYE 1018
Query: 56 CACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFS-S 114
C CKQGF ++ + C D+DEC C N C+N G Y+C+C S
Sbjct: 1019 CYCKQGF-------YYDGNLLECVDVDECLDESN-CR-NGVCENTRGGYRCACTPPAEYS 1069
Query: 115 PTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGFI---------- 164
P + + D++EC + C CVN GSY C C+ ++
Sbjct: 1070 PAQRQCLSPEE-----MDVDECQDPAAC-RPGRCVNLPGSYRCECRPPWVPGPSGRDCQL 1123
Query: 165 ---------SRNSTC-----EDVDECADPRACP----EHATCNNTVGNYSCFCNP----- 201
R C ED CA P A P + C G + C P
Sbjct: 1124 PESPAERAPERRDVCWSQRGED-GMCAGPLAGPALTFDDCCCRQGRG-WGAQCRPCPPRG 1181
Query: 202 -GFE---SSSGHLSFQGLK------------ASCEDIDECTEMCPINSTCTNTPGSYFCT 245
G S S SF +S ED DEC C ++ C PG C
Sbjct: 1182 AGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECR--C-VSGRCVPRPGGAVCE 1238
Query: 246 CHPGFAPSNGQLNFTDQGVECRDIDECRQ--DPSTCGPNSICTNALGSYSCGCIAGF-HP 302
C GF QL+ + C DIDECR+ + C N GS+ C C AGF
Sbjct: 1239 CPGGF-----QLDASR--ARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARS 1291
Query: 303 NPEGS 307
P G+
Sbjct: 1292 RPHGA 1296
Score = 73.2 bits (178), Expect = 1e-12
Identities = 77/301 (25%), Positives = 109/301 (36%), Gaps = 50/301 (16%)
Query: 41 CPAYATCTNTVDSYYCACK--QGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCK 98
CP Y++ ++ C +G+ N ++ P R DIDEC C
Sbjct: 959 CPVYSSA-----EFHSLCPDGKGYTQDNNIVNYGIPAHR--DIDECMLFGSEICKEGKCV 1011
Query: 99 NLSGRYKCSCLDGFSSPTGNDWVPGKPGNF-SCTDINECLTSSVCPEHSDCVNSMGSYSC 157
N Y+C C GF GN C D++ECL S C + C N+ G Y C
Sbjct: 1012 NTQPGYECYCKQGFYYD----------GNLLECVDVDECLDESNC-RNGVCENTRGGYRC 1060
Query: 158 SCQ--VGFISRNSTC-----EDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHL 210
+C + C DVDEC DP AC C N G+Y C C P +
Sbjct: 1061 ACTPPAEYSPAQRQCLSPEEMDVDECQDPAAC-RPGRCVNLPGSYRCECRPPWVPGPSGR 1119
Query: 211 SFQGLKASCEDIDECTEMC----PINSTCTNT---PGSYF--CTCHPGFAPSNGQLNFTD 261
Q ++ E E ++C + C P F C C G
Sbjct: 1120 DCQLPESPAERAPERRDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQG----------RG 1169
Query: 262 QGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQKDGNFSCQRVLFK 321
G +CR R S C + +N+ S + G P E S ++ + C+ V +
Sbjct: 1170 WGAQCRPCPP-RGAGSHCPTSQSESNSFWDTS-PLLLGKPPRDEDSSEEDSDECRCVSGR 1227
Query: 322 C 322
C
Sbjct: 1228 C 1228
Score = 48.1 bits (113), Expect = 4e-05
Identities = 22/51 (43%), Positives = 27/51 (52%), Gaps = 2/51 (3%)
Query: 153 GSYSCSCQVGFISRNST-CEDVDECADPRACPEHATCNNTVGNYSCFCNPG 202
G C G+ NST C+D++ECA P C H C N G+Y C C PG
Sbjct: 335 GEVGADCPQGYKRLNSTHCQDINECAMPGVC-RHGDCLNNPGSYRCVCPPG 384
Score = 46.2 bits (108), Expect = 1e-04
Identities = 69/289 (23%), Positives = 98/289 (33%), Gaps = 60/289 (20%)
Query: 58 CKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFS-SPT 116
C QG+ N + C+DI+EC+ P C + C N G Y+C C G S P+
Sbjct: 341 CPQGYKRLNSTH--------CQDINECAM-PGVCR-HGDCLNNPGSYRCVCPPGHSLGPS 390
Query: 117 GNDWVPGKPGNFSCTDINECLTSSVCPEHS---DCVNSMGSYSCSCQVG--FISRNSTCE 171
+ KP S C V PEH + C C VG + +R C
Sbjct: 391 RTQCIADKPEEKSL-----CF-RLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCP 444
Query: 172 DVDECADPRACP---------EHATCN-NTVGNYSCFCNPGFESSSGHLSFQGLKA-SCE 220
A CP H T ++S F +P L +A E
Sbjct: 445 TDGTAAFKEICPAGKGYHILTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSQAPPPE 504
Query: 221 DIDE---CTEMCPINS---------TCTNTPGSYFCTC------------HPGFAPSNGQ 256
D +E T P++ T T TP + P PS
Sbjct: 505 DTEEERGVTTDSPVSEERSVQQSHPTATTTPARPYPELISRPSPPTMRWFLPDLPPSRSA 564
Query: 257 LNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPE 305
+ + + DECR + + CG + C YSC C G+ +P+
Sbjct: 565 VEIAP--TQVTETDECRLNQNICG-HGECVPGPPDYSCHCNPGYRSHPQ 610
Score = 43.9 bits (102), Expect = 7e-04
Identities = 32/97 (32%), Positives = 39/97 (40%), Gaps = 19/97 (19%)
Query: 84 CSQSPQP--------CGPNSSCKNLSGRYKCSCLD--GFSSP------TGNDWVPG--KP 125
C +P P CG + S +KC L G P G D G +
Sbjct: 289 CGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRL 348
Query: 126 GNFSCTDINECLTSSVCPEHSDCVNSMGSYSCSCQVG 162
+ C DINEC VC H DC+N+ GSY C C G
Sbjct: 349 NSTHCQDINECAMPGVC-RHGDCLNNPGSYRCVCPPG 384
Score = 32.0 bits (71), Expect = 2.6
Identities = 27/104 (25%), Positives = 39/104 (37%), Gaps = 8/104 (7%)
Query: 266 CRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQKDGNFSCQRVLFKCKED 325
C+DI+EC P C C N GSY C C G P +Q + ++ L C
Sbjct: 353 CQDINECAM-PGVCRHGD-CLNNPGSYRCVCPPGHSLGPSRTQCIADKPEEKSL--CFRL 408
Query: 326 VIPDNKQIQQCQEGTAVKPAYVSFCAQINNIFSVLDKVCENKTT 369
V P++ QCQ + C + + + C T
Sbjct: 409 VSPEH----QCQHPLTTRLTRQLCCCSVGKAWGARCQRCPTDGT 448
>gi|18497288 latent transforming growth factor beta binding protein
3 isoform 2 [Homo sapiens]
Length = 1256
Score = 174 bits (442), Expect = 2e-43
Identities = 101/300 (33%), Positives = 141/300 (47%), Gaps = 42/300 (14%)
Query: 22 IRPTRKPNTKGNNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDI 81
I PT+ T + CR + + C Y C C G+ S+ Q+ + C D+
Sbjct: 567 IAPTQVTET--DECRLNQNICGHGECVPGPPDYSCHCNPGY-RSHPQHRY------CVDV 617
Query: 82 DECSQSPQPCGPNSS-CKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSS 140
+EC +PCGP C N G Y C C G+ G G SC D+NEC
Sbjct: 618 NECEA--EPCGPGRGICMNTGGSYNCHCNRGYRLHVG-------AGGRSCVDLNECAKPH 668
Query: 141 VCPEHSDCVNSMGSYSCSCQVGF---ISRNSTCEDVDECADPRACPEHATCNNTVGNYSC 197
+C + C+N G Y C+C G+ SR CED+DEC DP +CP+ C N G++ C
Sbjct: 669 LCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPD-GKCENKPGSFKC 727
Query: 198 F-CNPGFESSSGHLSFQGLKASCEDIDECTEMCPIN-STCTNTPGSYFCTCHPGFAPSNG 255
C PG+ S G +C D++EC E P + C N PGS+ CTC G+AP+
Sbjct: 728 IACQPGYRSQGG--------GACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPA-- 777
Query: 256 QLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQKDGNFSC 315
G C D+DEC C N IC+N GS+ C C++G+H + + S + C
Sbjct: 778 -----PDGRSCLDVDECEAG-DVCD-NGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDEC 830
Score = 165 bits (417), Expect = 2e-40
Identities = 106/311 (34%), Positives = 135/311 (43%), Gaps = 63/311 (20%)
Query: 33 NNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCG 92
N C P C NT SY C C +G+ + H G C D++EC++ P CG
Sbjct: 618 NECEAEPCGPGRGICMNTGGSYNCHCNRGY-----RLHVGAGGRSCVDLNECAK-PHLCG 671
Query: 93 PNSSCKNLSGRYKCSCLDGF--------------------SSPTGNDWVPGKPGNF---- 128
C N G YKC+C G+ S P G KPG+F
Sbjct: 672 DGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGK--CENKPGSFKCIA 729
Query: 129 -----------SCTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGFISR--NSTCEDVDE 175
+C D+NEC S C C N GS+ C+C G+ +C DVDE
Sbjct: 730 CQPGYRSQGGGACRDVNECAEGSPCSP-GWCENLPGSFRCTCAQGYAPAPDGRSCLDVDE 788
Query: 176 CADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECT-EMCPINST 234
C C ++ C+NT G++ C C G+ HLS ++ CEDIDEC I
Sbjct: 789 CEAGDVC-DNGICSNTPGSFQCQCLSGY-----HLSRD--RSHCEDIDECDFPAACIGGD 840
Query: 235 CTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSC 294
C NT GSY C C G G+ +C+DIDEC QDPS C P+ C N GSY C
Sbjct: 841 CINTNGSYRCLCPQGHRLVGGR--------KCQDIDECSQDPSLCLPHGACKNLQGSYVC 892
Query: 295 GCIAGFHPNPE 305
C GF P +
Sbjct: 893 VCDEGFTPTQD 903
Score = 117 bits (292), Expect = 6e-26
Identities = 94/337 (27%), Positives = 136/337 (40%), Gaps = 83/337 (24%)
Query: 33 NNCRDSTLCPAYATCTNTVDSYYC-ACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPC 91
+ CRD + CP C N S+ C AC+ G+ S G C+D++EC++ PC
Sbjct: 705 DECRDPSSCPD-GKCENKPGSFKCIACQPGYRSQGGG--------ACRDVNECAEG-SPC 754
Query: 92 GPNSSCKNLSGRYKCSCLDGFS-SPTG----------------NDWVPGKPGNFSCT--- 131
P C+NL G ++C+C G++ +P G N PG+F C
Sbjct: 755 SPGW-CENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLS 813
Query: 132 ------------DINECLTSSVCPEHSDCVNSMGSYSCSCQVGF-ISRNSTCEDVDECA- 177
DI+EC + C DC+N+ GSY C C G + C+D+DEC+
Sbjct: 814 GYHLSRDRSHCEDIDECDFPAACIG-GDCINTNGSYRCLCPQGHRLVGGRKCQDIDECSQ 872
Query: 178 DPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGL-----KASC----EDIDECTEM 228
DP C H C N G+Y C C+ GF + + + K C +D C +
Sbjct: 873 DPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSV 932
Query: 229 CPINST---CTNTPGSYF---CTCHP-----------------GFAPSNGQLNFTDQGVE 265
N T C + G+ + C +P G+ N +N+ G+
Sbjct: 933 LATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNY---GIP 989
Query: 266 C-RDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFH 301
RDIDEC S C N Y C C GF+
Sbjct: 990 AHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFY 1026
Score = 103 bits (257), Expect = 7e-22
Identities = 85/281 (30%), Positives = 117/281 (41%), Gaps = 57/281 (20%)
Query: 33 NNCRDSTLCPAYATCT-----NTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQS 87
++C D C A C NT SY C C QG H G +C+DIDECSQ
Sbjct: 822 SHCEDIDECDFPAACIGGDCINTNGSYRCLCPQG--------HRLVGGRKCQDIDECSQD 873
Query: 88 PQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSD 147
P C P+ +CKNL G Y C C +GF +PT + C ++ + C + D
Sbjct: 874 PSLCLPHGACKNLQGSYVCVCDEGF-TPTQD--------QHGCEEVEQPHHKKECYLNFD 924
Query: 148 --------CVNSMGSYSCSCQVGFISRNSTCEDVDECADPRACPEHATCNNTVGNYSCFC 199
++ C C +G CE + C + H+ C +
Sbjct: 925 DTVFCDSVLATNVTQQECCCSLG-AGWGDHCE-IYPCPVYSSAEFHSLCPD--------- 973
Query: 200 NPGFESSSGHLSFQGLKASCEDIDEC----TEMCPINSTCTNTPGSYFCTCHPGFAPSNG 255
G+ + +++ G+ A DIDEC +E+C C NT Y C C GF +G
Sbjct: 974 GKGYTQDNNIVNY-GIPAH-RDIDECMLFGSEICK-EGKCVNTQPGYECYCKQGFY-YDG 1029
Query: 256 QLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGC 296
L +EC D+DEC D S C N +C N G Y C C
Sbjct: 1030 NL------LECVDVDEC-LDESNC-RNGVCENTRGGYRCAC 1062
Score = 82.8 bits (203), Expect = 1e-15
Identities = 88/327 (26%), Positives = 123/327 (37%), Gaps = 57/327 (17%)
Query: 36 RDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQN--------HFK-------DPGVRCKD 80
+D +LC + C N SY C C +GF + Q+ H K D V C
Sbjct: 872 QDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDS 931
Query: 81 IDECSQSPQPC------GPNSSCKNL------SGRYKCSCLDGFSSPTGNDWVP-GKPGN 127
+ + + Q C G C+ S + C DG N+ V G P +
Sbjct: 932 VLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAH 991
Query: 128 FSCTDINECLT--SSVCPEHSDCVNSMGSYSCSCQVGFISRNST--CEDVDECADPRACP 183
DI+EC+ S +C E CVN+ Y C C+ GF + C DVDEC D C
Sbjct: 992 ---RDIDECMLFGSEICKE-GKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNC- 1046
Query: 184 EHATCNNTVGNYSCFCNPGFESSSGH---LSFQGLKASCEDIDECTEMCPINSTCTNT-- 238
+ C NT G Y C C P E S LS + ++ + E D C + C
Sbjct: 1047 RNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMERAPERRDVCWSQRGEDGMCAGPLA 1106
Query: 239 -PGSYF--CTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCG 295
P F C C G G +CR R S C + +N+ S
Sbjct: 1107 GPALTFDDCCCRQG----------RGWGAQCRPCPP-RGAGSHCPTSQSESNSFWDTS-P 1154
Query: 296 CIAGFHPNPEGSQKDGNFSCQRVLFKC 322
+ G P E S ++ + C+ V +C
Sbjct: 1155 LLLGKPPRDEDSSEEDSDECRCVSGRC 1181
Score = 70.5 bits (171), Expect = 7e-12
Identities = 85/320 (26%), Positives = 112/320 (35%), Gaps = 82/320 (25%)
Query: 41 CPAYATCTNTVDSYYCACK--QGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCK 98
CP Y++ ++ C +G+ N ++ P R DIDEC C
Sbjct: 959 CPVYSSA-----EFHSLCPDGKGYTQDNNIVNYGIPAHR--DIDECMLFGSEICKEGKCV 1011
Query: 99 NLSGRYKCSCLDGFSSPTGNDWVPGKPGNF-SCTDINECLTSSVCPEHSDCVNSMGSYSC 157
N Y+C C GF GN C D++ECL S C + C N+ G Y C
Sbjct: 1012 NTQPGYECYCKQGFYYD----------GNLLECVDVDECLDESNC-RNGVCENTRGGYRC 1060
Query: 158 SCQ--VGFISRNSTCEDVDE--------------------CADPRACP----EHATCNNT 191
+C + C +E CA P A P + C
Sbjct: 1061 ACTPPAEYSPAQRQCLSPEEMERAPERRDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQG 1120
Query: 192 VGNYSCFCNP------GFE---SSSGHLSFQGLK------------ASCEDIDECTEMCP 230
G + C P G S S SF +S ED DEC C
Sbjct: 1121 RG-WGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECR--C- 1176
Query: 231 INSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQ--DPSTCGPNSICTNA 288
++ C PG C C GF QL+ + C DIDECR+ + C N
Sbjct: 1177 VSGRCVPRPGGAVCECPGGF-----QLDASR--ARCVDIDECRELNQRGLLCKSERCVNT 1229
Query: 289 LGSYSCGCIAGF-HPNPEGS 307
GS+ C C AGF P G+
Sbjct: 1230 SGSFRCVCKAGFARSRPHGA 1249
Score = 48.1 bits (113), Expect = 4e-05
Identities = 22/51 (43%), Positives = 27/51 (52%), Gaps = 2/51 (3%)
Query: 153 GSYSCSCQVGFISRNST-CEDVDECADPRACPEHATCNNTVGNYSCFCNPG 202
G C G+ NST C+D++ECA P C H C N G+Y C C PG
Sbjct: 335 GEVGADCPQGYKRLNSTHCQDINECAMPGVC-RHGDCLNNPGSYRCVCPPG 384
Score = 46.2 bits (108), Expect = 1e-04
Identities = 69/289 (23%), Positives = 98/289 (33%), Gaps = 60/289 (20%)
Query: 58 CKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFS-SPT 116
C QG+ N + C+DI+EC+ P C + C N G Y+C C G S P+
Sbjct: 341 CPQGYKRLNSTH--------CQDINECAM-PGVCR-HGDCLNNPGSYRCVCPPGHSLGPS 390
Query: 117 GNDWVPGKPGNFSCTDINECLTSSVCPEHS---DCVNSMGSYSCSCQVG--FISRNSTCE 171
+ KP S C V PEH + C C VG + +R C
Sbjct: 391 RTQCIADKPEEKSL-----CF-RLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCP 444
Query: 172 DVDECADPRACP---------EHATCN-NTVGNYSCFCNPGFESSSGHLSFQGLKA-SCE 220
A CP H T ++S F +P L +A E
Sbjct: 445 TDGTAAFKEICPAGKGYHILTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSQAPPPE 504
Query: 221 DIDE---CTEMCPINS---------TCTNTPGSYFCTC------------HPGFAPSNGQ 256
D +E T P++ T T TP + P PS
Sbjct: 505 DTEEERGVTTDSPVSEERSVQQSHPTATTTPARPYPELISRPSPPTMRWFLPDLPPSRSA 564
Query: 257 LNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPE 305
+ + + DECR + + CG + C YSC C G+ +P+
Sbjct: 565 VEIAP--TQVTETDECRLNQNICG-HGECVPGPPDYSCHCNPGYRSHPQ 610
Score = 43.9 bits (102), Expect = 7e-04
Identities = 32/97 (32%), Positives = 39/97 (40%), Gaps = 19/97 (19%)
Query: 84 CSQSPQP--------CGPNSSCKNLSGRYKCSCLD--GFSSP------TGNDWVPG--KP 125
C +P P CG + S +KC L G P G D G +
Sbjct: 289 CGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRL 348
Query: 126 GNFSCTDINECLTSSVCPEHSDCVNSMGSYSCSCQVG 162
+ C DINEC VC H DC+N+ GSY C C G
Sbjct: 349 NSTHCQDINECAMPGVC-RHGDCLNNPGSYRCVCPPG 384
Score = 36.6 bits (83), Expect = 0.11
Identities = 26/92 (28%), Positives = 37/92 (40%), Gaps = 12/92 (13%)
Query: 26 RKPNTKGNNCRDSTLCPAYA-TCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDEC 84
+ P + ++ DS C + C C C GF + RC DIDEC
Sbjct: 1159 KPPRDEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASR-------ARCVDIDEC 1211
Query: 85 SQSPQP---CGPNSSCKNLSGRYKCSCLDGFS 113
+ Q C + C N SG ++C C GF+
Sbjct: 1212 RELNQRGLLC-KSERCVNTSGSFRCVCKAGFA 1242
Score = 32.0 bits (71), Expect = 2.6
Identities = 27/104 (25%), Positives = 39/104 (37%), Gaps = 8/104 (7%)
Query: 266 CRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQKDGNFSCQRVLFKCKED 325
C+DI+EC P C C N GSY C C G P +Q + ++ L C
Sbjct: 353 CQDINECAM-PGVCRHGD-CLNNPGSYRCVCPPGHSLGPSRTQCIADKPEEKSL--CFRL 408
Query: 326 VIPDNKQIQQCQEGTAVKPAYVSFCAQINNIFSVLDKVCENKTT 369
V P++ QCQ + C + + + C T
Sbjct: 409 VSPEH----QCQHPLTTRLTRQLCCCSVGKAWGARCQRCPTDGT 448
>gi|4557733 latent transforming growth factor beta binding protein 2
[Homo sapiens]
Length = 1821
Score = 173 bits (439), Expect = 6e-43
Identities = 102/283 (36%), Positives = 143/283 (50%), Gaps = 45/283 (15%)
Query: 33 NNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCG 92
N C +C A+ CTN S+ C+C+QG+ ++ + C+D+DEC+ S C
Sbjct: 1012 NECLTPGVC-AHGKCTNLEGSFRCSCEQGYEVTSDEKG-------CQDVDECA-SRASC- 1061
Query: 93 PNSSCKNLSGRYKCS-CLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNS 151
P C N G + CS C +G+ WV +C D++EC VCP C N+
Sbjct: 1062 PTGLCLNTEGSFACSACENGY-------WV--NEDGTACEDLDECAFPGVCPS-GVCTNT 1111
Query: 152 MGSYSCS-CQVGFISR--NSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSG 208
GS+SC C G+ +CEDVDEC DP++ C NTVG+Y C C GF+ ++G
Sbjct: 1112 AGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLANG 1171
Query: 209 HLSFQGLKASCEDIDEC--TEMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVEC 266
+ CED++EC E C + C N+ GS+FC C PGF + G G C
Sbjct: 1172 TV--------CEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEG-------GTSC 1216
Query: 267 RDIDEC-RQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQ 308
+D+DEC DP G C N GS++C C GF P+PE +
Sbjct: 1217 QDVDECATTDPCVGGH---CVNTEGSFNCLCETGFQPSPESGE 1256
Score = 170 bits (431), Expect = 5e-42
Identities = 107/300 (35%), Positives = 140/300 (46%), Gaps = 48/300 (16%)
Query: 33 NNCRDSTLCPAYATCTNTVDSYYCA-CKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPC 91
+ C +CP+ CTNT S+ C C G+ S G C+D+DEC + PQ
Sbjct: 1095 DECAFPGVCPS-GVCTNTAGSFSCKDCDGGYRPS-------PLGDSCEDVDEC-EDPQSS 1145
Query: 92 GPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNS 151
CKN G Y+C C GF G C D+NEC+ C H +C+NS
Sbjct: 1146 CLGGECKNTVGSYQCLCPQGFQLANGT----------VCEDVNECMGEEHCAPHGECLNS 1195
Query: 152 MGSYSCSCQVGFISRN--STCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGH 209
GS+ C C GF+S ++C+DVDECA C C NT G+++C C GF+ S
Sbjct: 1196 HGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVG-GHCVNTEGSFNCLCETGFQPSPE- 1253
Query: 210 LSFQGLKASCEDIDECTEMC-PINST--CTNTPGSYFCT--CHPGF--APSNGQLNFTDQ 262
C DIDEC + P+ T C N+PGSY C C PGF AP+
Sbjct: 1254 ------SGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNG-------- 1299
Query: 263 GVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQKDGNFSCQRVLFKC 322
+C DIDEC D + CG + C N GS+ C C GF +P G C+ +L C
Sbjct: 1300 --DCIDIDECAND-TMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVC 1356
Score = 166 bits (420), Expect = 9e-41
Identities = 110/340 (32%), Positives = 155/340 (45%), Gaps = 46/340 (13%)
Query: 22 IRPTRKPNTKGNNC-RDSTLCPAYATCTNTVDSYYCACKQGF-LSSNGQNHFKDPGVRCK 79
+ P++ T N C RD C C N V SY C C G+ L+++G C+
Sbjct: 878 LHPSQAYCTDDNECLRDP--CKGKGRCINRVGSYSCFCYPGYTLATSGATQ------ECQ 929
Query: 80 DIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTS 139
DI+EC Q P C C N G Y C C G+ + + G+ C DINEC
Sbjct: 930 DINECEQ-PGVCS-GGQCTNTEGSYHCECDQGY--------IMVRKGH--CQDINECRHP 977
Query: 140 SVCPEHSDCVNSMGSYSC-SCQVGFISRNSTCEDVDECADPRACPEHATCNNTVGNYSCF 198
CP+ CVNS GSY+C +C+ G+ ++ +C DV+EC P C H C N G++ C
Sbjct: 978 GTCPD-GRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLTPGVC-AHGKCTNLEGSFRCS 1035
Query: 199 CNPGFESSSGHLSFQGLKASCEDIDECTE--MCPINSTCTNTPGSYFCT-CHPGFAPSNG 255
C G+E +S + C+D+DEC CP C NT GS+ C+ C G+
Sbjct: 1036 CEQGYEVTSD-------EKGCQDVDECASRASCP-TGLCLNTEGSFACSACENGYW---- 1083
Query: 256 QLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSC-GCIAGFHPNPEGSQKDGNFS 314
+ G C D+DEC P C P+ +CTN GS+SC C G+ P+P G +
Sbjct: 1084 ---VNEDGTACEDLDEC-AFPGVC-PSGVCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDE 1138
Query: 315 CQRVLFKCKEDVIPDNKQIQQCQEGTAVKPAYVSFCAQIN 354
C+ C + QC + A + C +N
Sbjct: 1139 CEDPQSSCLGGECKNTVGSYQCLCPQGFQLANGTVCEDVN 1178
Score = 131 bits (329), Expect = 3e-30
Identities = 78/222 (35%), Positives = 104/222 (46%), Gaps = 35/222 (15%)
Query: 33 NNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCG 92
N C C + C N+ S++C C GF+S+ G G C+D+DEC+ + PC
Sbjct: 1178 NECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEG-------GTSCQDVDECATT-DPC- 1228
Query: 93 PNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINEC--LTSSVCPEHSDCVN 150
C N G + C C GF P + C DI+EC VC C N
Sbjct: 1229 VGGHCVNTEGSFNCLCETGFQP---------SPESGECVDIDECEDYGDPVCGTWK-CEN 1278
Query: 151 SMGSYSC--SCQVGF-ISRNSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFE-SS 206
S GSY C CQ GF ++ N C D+DECA+ C H C+NT G++ C C+ GFE S
Sbjct: 1279 SPGSYRCVLGCQPGFHMAPNGDCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISP 1338
Query: 207 SGHLSFQGLKASCEDIDECTEMCPI--NSTCTNTPGSYFCTC 246
SG C D++EC M + + C N GS+ C C
Sbjct: 1339 SGW--------DCVDVNECELMLAVCGAALCENVEGSFLCLC 1372
Score = 124 bits (312), Expect = 3e-28
Identities = 78/228 (34%), Positives = 103/228 (45%), Gaps = 40/228 (17%)
Query: 81 IDECSQ-SPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTS 139
ID C+ + CGP + C NL Y+C C G+ P CTD NECL
Sbjct: 845 IDRCAAGATNVCGPGT-CVNLPDGYRCVCSPGYQL---------HPSQAYCTDDNECLRD 894
Query: 140 SVCPEHSDCVNSMGSYSCSCQVGFISRNS----TCEDVDECADPRACPEHATCNNTVGNY 195
C C+N +GSYSC C G+ S C+D++EC P C C NT G+Y
Sbjct: 895 P-CKGKGRCINRVGSYSCFCYPGYTLATSGATQECQDINECEQPGVC-SGGQCTNTEGSY 952
Query: 196 SCFCNPGFESSSGHLSFQGLKASCEDIDECTE--MCPINSTCTNTPGSYFC-TCHPGFAP 252
C C+ G+ K C+DI+EC CP + C N+PGSY C C G+
Sbjct: 953 HCECDQGY--------IMVRKGHCQDINECRHPGTCP-DGRCVNSPGSYTCLACEEGYRG 1003
Query: 253 SNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGF 300
+G C D++EC P C + CTN GS+ C C G+
Sbjct: 1004 QSG---------SCVDVNEC-LTPGVCA-HGKCTNLEGSFRCSCEQGY 1040
Score = 99.8 bits (247), Expect = 1e-20
Identities = 73/270 (27%), Positives = 101/270 (37%), Gaps = 73/270 (27%)
Query: 33 NNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCG 92
+ C + T+C ++ C NT S+ C C QGF G C D++EC CG
Sbjct: 1305 DECANDTMCGSHGFCDNTDGSFRCLCDQGF-------EISPSGWDCVDVNECELMLAVCG 1357
Query: 93 PNSSCKNLSGRYKCSCL-----------------------------DGFSSPTGNDWVPG 123
+ C+N+ G + C C D +PT D G
Sbjct: 1358 A-ALCENVEGSFLCLCASDLEEYDAQEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSG 1416
Query: 124 KPGNFSCTDI-------NECLTSS---------VCPEHSDCVNSMGSYSCSCQVGFIS-- 165
+ G+ C+ + EC + +CP ++ S C G+I
Sbjct: 1417 QKGHAPCSSVLGRNTTQAECCCTQGASWGDACDLCPSED---SAEFSEICPSGKGYIPVE 1473
Query: 166 -----RNSTCEDVDECA--DPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKAS 218
+ D DEC P CP + C NTV Y C CNPGF + H
Sbjct: 1474 GAWTFGQTMYTDADECVIFGPGLCP-NGRCLNTVPGYVCLCNPGFHYDASH-------KK 1525
Query: 219 CEDIDECTEMCPINSTCTNTPGSYFCTCHP 248
CED DEC ++ N C NT GS+ C C P
Sbjct: 1526 CEDHDECQDLACENGECVNTEGSFHCFCSP 1555
Score = 93.6 bits (231), Expect = 7e-19
Identities = 91/337 (27%), Positives = 125/337 (37%), Gaps = 99/337 (29%)
Query: 27 KPNTKGNNCRDSTLCPAYAT-------CTNTVDSYYCA--CKQGF-LSSNGQNHFKDPGV 76
+P+ + C D C Y C N+ SY C C+ GF ++ NG
Sbjct: 1249 QPSPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGD-------- 1300
Query: 77 RCKDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFS-SPTGNDWVPGKPGNFSCTDINE 135
C DIDEC+ CG + C N G ++C C GF SP+G D C D+NE
Sbjct: 1301 -CIDIDECANDTM-CGSHGFCDNTDGSFRCLCDQGFEISPSGWD----------CVDVNE 1348
Query: 136 C-LTSSVCPEHSDCVNSMGSYSCSC---------QVGFIS-RNSTCEDVDECADPRACPE 184
C L +VC + C N GS+ C C Q G R + + + E P
Sbjct: 1349 CELMLAVCGA-ALCENVEGSFLCLCASDLEEYDAQEGHCRPRGAGGQSMSEAPTGDHAPA 1407
Query: 185 ------------HATCNNTVGNYS----CFCNPGFE---------------------SSS 207
HA C++ +G + C C G S
Sbjct: 1408 PTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQGASWGDACDLCPSEDSAEFSEICPSGK 1467
Query: 208 GHLSFQGL----KASCEDIDECT----EMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNF 259
G++ +G + D DEC +CP N C NT Y C C+PGF ++
Sbjct: 1468 GYIPVEGAWTFGQTMYTDADECVIFGPGLCP-NGRCLNTVPGYVCLCNPGF-------HY 1519
Query: 260 TDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGC 296
+C D DEC+ N C N GS+ C C
Sbjct: 1520 DASHKKCEDHDECQD---LACENGECVNTEGSFHCFC 1553
Score = 74.7 bits (182), Expect = 4e-13
Identities = 45/127 (35%), Positives = 59/127 (46%), Gaps = 15/127 (11%)
Query: 187 TCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECT-EMCPINSTCTNTPGSYFCT 245
TC N Y C C+PG++ +A C D +EC + C C N GSY C
Sbjct: 860 TCVNLPDGYRCVCSPGYQLHPS-------QAYCTDDNECLRDPCKGKGRCINRVGSYSCF 912
Query: 246 CHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPE 305
C+PG+ L + EC+DI+EC Q P C CTN GSY C C G+ +
Sbjct: 913 CYPGYT-----LATSGATQECQDINECEQ-PGVCSGGQ-CTNTEGSYHCECDQGYIMVRK 965
Query: 306 GSQKDGN 312
G +D N
Sbjct: 966 GHCQDIN 972
Score = 59.3 bits (142), Expect = 2e-08
Identities = 32/92 (34%), Positives = 43/92 (46%), Gaps = 6/92 (6%)
Query: 122 PGKPGNFSCTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGFI--SRNSTCEDVDECAD- 178
P P F EC + C E+ CV Y+C C GF + + C DV+EC D
Sbjct: 1723 PEPPAGFEGLQAEECGILNGC-ENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDL 1781
Query: 179 --PRACPEHATCNNTVGNYSCFCNPGFESSSG 208
P H C NT G+Y C C+PG+ + +G
Sbjct: 1782 NGPAVLCVHGYCENTEGSYRCHCSPGYVAEAG 1813
Score = 54.3 bits (129), Expect = 5e-07
Identities = 33/97 (34%), Positives = 42/97 (43%), Gaps = 14/97 (14%)
Query: 218 SCEDIDEC----TEMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECR 273
S ID C T +C TC N P Y C C PG+ Q C D +EC
Sbjct: 841 STPGIDRCAAGATNVCG-PGTCVNLPDGYRCVCSPGYQLHPSQ-------AYCTDDNECL 892
Query: 274 QDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQKD 310
+DP C C N +GSYSC C G+ G+ ++
Sbjct: 893 RDP--CKGKGRCINRVGSYSCFCYPGYTLATSGATQE 927
Score = 53.1 bits (126), Expect = 1e-06
Identities = 79/342 (23%), Positives = 106/342 (30%), Gaps = 110/342 (32%)
Query: 40 LCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKN 99
LCP C NTV Y C C GF H+ +C+D DEC C N C N
Sbjct: 1496 LCPN-GRCLNTVPGYVCLCNPGF-------HYDASHKKCEDHDECQDLA--C-ENGECVN 1544
Query: 100 LSGRYKC-------------SCLDGFSSPTG----------------NDWVPGKPGNFSC 130
G + C C++ SS ND V +P
Sbjct: 1545 TEGSFHCFCSPPLTLDLSQQRCMNSTSSTEDLPDHDIHMDICWKKVTND-VCSEPLRGHR 1603
Query: 131 TDINECLTS---------SVCPEHSDCVNSMGSYSCSCQVGFISRNSTC----------- 170
T EC ++CP S V Y+ C V I
Sbjct: 1604 TTYTECCCQDGEAWSQQCALCPPRSSEV-----YAQLCNVARIEAEREAGVHFRPGYEYG 1658
Query: 171 EDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLS------------------- 211
D+ P+ A N +G P F +++GH +
Sbjct: 1659 PGPDDLHYSIYGPDGAPFYNYLGPEDTVPEPAFPNTAGHSADRTPILESPLQPSELQPHY 1718
Query: 212 ----------FQGLKAS-CEDIDECTEMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFT 260
F+GL+A C ++ C N C Y C C GF QL+
Sbjct: 1719 VASHPEPPAGFEGLQAEECGILNGCE-----NGRCVRVREGYTCDCFEGF-----QLDAA 1768
Query: 261 DQGVECRDIDECRQ--DPSTCGPNSICTNALGSYSCGCIAGF 300
C D++EC P+ + C N GSY C C G+
Sbjct: 1769 HMA--CVDVNECDDLNGPAVLCVHGYCENTEGSYRCHCSPGY 1808
Score = 50.8 bits (120), Expect = 5e-06
Identities = 25/82 (30%), Positives = 40/82 (48%), Gaps = 3/82 (3%)
Query: 174 DECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTEMCPINS 233
+EC C E+ C Y+C C GF+ + H++ + C+D++ +C ++
Sbjct: 1735 EECGILNGC-ENGRCVRVREGYTCDCFEGFQLDAAHMACVDVN-ECDDLNGPAVLC-VHG 1791
Query: 234 TCTNTPGSYFCTCHPGFAPSNG 255
C NT GSY C C PG+ G
Sbjct: 1792 YCENTEGSYRCHCSPGYVAEAG 1813
Score = 45.4 bits (106), Expect = 2e-04
Identities = 18/35 (51%), Positives = 26/35 (74%), Gaps = 1/35 (2%)
Query: 130 CTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGFI 164
C DINECLT +C + ++CVN+ GSY C+C+ G +
Sbjct: 620 CQDINECLTLGLCKD-AECVNTRGSYLCTCRPGLM 653
Score = 44.3 bits (103), Expect = 5e-04
Identities = 22/75 (29%), Positives = 32/75 (42%), Gaps = 12/75 (16%)
Query: 94 NSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINEC---LTSSVCPEHSDCVN 150
N C + Y C C +GF + +C D+NEC +V H C N
Sbjct: 1745 NGRCVRVREGYTCDCFEGFQLDA---------AHMACVDVNECDDLNGPAVLCVHGYCEN 1795
Query: 151 SMGSYSCSCQVGFIS 165
+ GSY C C G+++
Sbjct: 1796 TEGSYRCHCSPGYVA 1810
Score = 40.4 bits (93), Expect = 0.007
Identities = 25/80 (31%), Positives = 35/80 (43%), Gaps = 20/80 (25%)
Query: 219 CEDIDECTEM--CPINSTCTNTPGSYFCTCHPGFA--PSNGQLNFTDQGVECRDIDECRQ 274
C+DI+EC + C ++ C NT GSY CTC PG PS + C
Sbjct: 620 CQDINECLTLGLCK-DAECVNTRGSYLCTCRPGLMLDPSRSR---------------CVS 663
Query: 275 DPSTCGPNSICTNALGSYSC 294
D + +C +LG +C
Sbjct: 664 DKAISMLQGLCYRSLGPGTC 683
Score = 38.9 bits (89), Expect = 0.021
Identities = 19/45 (42%), Positives = 25/45 (55%), Gaps = 2/45 (4%)
Query: 159 CQVGFISRNST-CEDVDECADPRACPEHATCNNTVGNYSCFCNPG 202
C G+ N T C+D++EC C + A C NT G+Y C C PG
Sbjct: 608 CPQGYKRLNLTHCQDINECLTLGLCKD-AECVNTRGSYLCTCRPG 651
Score = 38.1 bits (87), Expect = 0.036
Identities = 19/73 (26%), Positives = 29/73 (39%), Gaps = 9/73 (12%)
Query: 47 CTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQ--SPQPCGPNSSCKNLSGRY 104
C + Y C C +GF + C D++EC P + C+N G Y
Sbjct: 1748 CVRVREGYTCDCFEGFQLDAAH-------MACVDVNECDDLNGPAVLCVHGYCENTEGSY 1800
Query: 105 KCSCLDGFSSPTG 117
+C C G+ + G
Sbjct: 1801 RCHCSPGYVAEAG 1813
Score = 30.0 bits (66), Expect = 9.9
Identities = 20/55 (36%), Positives = 27/55 (49%), Gaps = 10/55 (18%)
Query: 256 QLNFTDQGVECRDIDECRQDPSTCG--PNSICTNALGSYSCGCIAGFHPNPEGSQ 308
+LN T C+DI+EC T G ++ C N GSY C C G +P S+
Sbjct: 614 RLNLT----HCQDINECL----TLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSR 660
Score = 30.0 bits (66), Expect = 9.9
Identities = 15/42 (35%), Positives = 20/42 (47%), Gaps = 5/42 (11%)
Query: 33 NNCRD----STLCPAYATCTNTVDSYYCACKQGFLSSNGQNH 70
N C D + LC + C NT SY C C G+++ G H
Sbjct: 1776 NECDDLNGPAVLC-VHGYCENTEGSYRCHCSPGYVAEAGPPH 1816
>gi|56237021 fibrillin 3 precursor [Homo sapiens]
Length = 2809
Score = 171 bits (434), Expect = 2e-42
Identities = 103/290 (35%), Positives = 133/290 (45%), Gaps = 47/290 (16%)
Query: 24 PTRKPNTKGNNCR-DSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDID 82
P R+ N CR + C + C NT SY C+C QG+ G C D+D
Sbjct: 1148 PDRQGCVDINECRVQNGGCDVH--CINTEGSYRCSCGQGY-------SLMPDGRACADVD 1198
Query: 83 ECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINEC-LTSSV 141
EC ++P+ C C N+ G ++C C DGF + P +C D++EC L +
Sbjct: 1199 ECEENPRVCD-QGHCTNMPGGHRCLCYDGFMAT---------PDMRTCVDVDECDLNPHI 1248
Query: 142 CPEHSDCVNSMGSYSCSCQVGFISRNST--CEDVDEC-ADPRACPEHATCNNTVGNYSCF 198
C H DC N+ GS+ C CQ+G++ R C DVDEC C HA+C N G++SC
Sbjct: 1249 CL-HGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCR 1307
Query: 199 CNPGFESSSGHLSFQGLKASCEDIDECTEM---CPINSTCTNTPGSYFCTCHPGFAPSNG 255
C PG + G C D+DEC C C N PGSY CTC GFA
Sbjct: 1308 CLPG---------WVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFA---- 1354
Query: 256 QLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPE 305
G C D DEC ++ C N C NA G Y C C GF P +
Sbjct: 1355 -----GDGFFCEDRDECAENVDLC-DNGQCLNAPGGYRCECEMGFDPTED 1398
Score = 168 bits (426), Expect = 2e-41
Identities = 92/266 (34%), Positives = 124/266 (46%), Gaps = 38/266 (14%)
Query: 44 YATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGR 103
+ C NT S+ C C+ G++ G C D+DEC C ++SC N+ G
Sbjct: 1251 HGDCENTKGSFVCHCQLGYMVRKG-------ATGCSDVDECEVGGHNCDSHASCLNIPGS 1303
Query: 104 YKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSV-CPEHSDCVNSMGSYSCSCQVG 162
+ C CL G WV F C D++EC++ C DC+N GSY C+C+ G
Sbjct: 1304 FSCRCLPG--------WVGD---GFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQG 1352
Query: 163 FISRNSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDI 222
F CED DECA+ ++ C N G Y C C GF+ + H +C+D+
Sbjct: 1353 FAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDH-------RACQDV 1405
Query: 223 DECTE--MCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCG 280
DEC + +C S C N PG + C C+ G+ G G C DI+EC DP C
Sbjct: 1406 DECAQGNLCAFGS-CENLPGMFRCICNGGYELDRG-------GGNCTDINEC-ADPVNC- 1455
Query: 281 PNSICTNALGSYSCGCIAGFHPNPEG 306
N +C N GSY C C F NP G
Sbjct: 1456 INGVCINTPGSYLCSCPQDFELNPSG 1481
Score = 161 bits (408), Expect = 2e-39
Identities = 92/279 (32%), Positives = 129/279 (46%), Gaps = 40/279 (14%)
Query: 33 NNCRDSTLCPAYATCTNTVDSYYCACKQGF-LSSNGQNHFKDPGVRCKDIDECSQSPQPC 91
N C+ + TC NTV S++CAC GF L + +N C DIDEC SP C
Sbjct: 988 NECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERN--------CTDIDECRISPDLC 1039
Query: 92 GPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNS 151
G +C N G ++C C G+ S G +C D++EC + C N+
Sbjct: 1040 G-QGTCVNTPGSFECECFPGYES--------GFMLMKNCMDVDECARDPLLCRGGTCTNT 1090
Query: 152 MGSYSCSCQVG--FISRNSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGH 209
GSY C C G ++ + CED+DEC+ H C N +G + C C+ GF+S+
Sbjct: 1091 DGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPD- 1149
Query: 210 LSFQGLKASCEDIDECTEM---CPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVEC 266
+ C DI+EC C ++ C NT GSY C+C G+ + G C
Sbjct: 1150 ------RQGCVDINECRVQNGGCDVH--CINTEGSYRCSCGQGY-------SLMPDGRAC 1194
Query: 267 RDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPE 305
D+DEC ++P C CTN G + C C GF P+
Sbjct: 1195 ADVDECEENPRVCDQGH-CTNMPGGHRCLCYDGFMATPD 1232
Score = 154 bits (388), Expect = 5e-37
Identities = 91/275 (33%), Positives = 123/275 (44%), Gaps = 44/275 (16%)
Query: 33 NNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCG 92
+ C + A C N + S+ C C GF ++ + C+D+DEC PC
Sbjct: 1723 DECGEIPAICANGICINQIGSFRCECPAGF-------NYNSILLACEDVDECGSRESPCQ 1775
Query: 93 PNSSCKNLSGRYKCSCLDGFS-SPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNS 151
N+ C N+ G Y+C C G+ SP G +C NEC H DC+++
Sbjct: 1776 QNADCINIPGSYRCKCTRGYKLSPGG-----------ACVGRNECREIPNVCSHGDCMDT 1824
Query: 152 MGSYSCSCQVGF--ISRNSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGH 209
GSY C C GF + + C D+DEC D + C + TC N +G+Y+C C PGF +
Sbjct: 1825 EGSYMCLCHRGFQASADQTLCMDIDEC-DRQPC-GNGTCKNIIGSYNCLCFPGFVVTH-- 1880
Query: 210 LSFQGLKASCEDIDECT----EMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVE 265
C D DECT ++C C NT GS+ C C GF T G
Sbjct: 1881 ------NGDCVDFDECTTLVGQVCRFGH-CLNTAGSFHCLCQDGF-------ELTADGKN 1926
Query: 266 CRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGF 300
C D +EC TC P + C N GS+ C C GF
Sbjct: 1927 CVDTNECLSLAGTCLPGT-CQNLEGSFRCICPPGF 1960
Score = 140 bits (353), Expect = 5e-33
Identities = 97/347 (27%), Positives = 133/347 (38%), Gaps = 90/347 (25%)
Query: 33 NNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCG 92
+ CR A+ C N++ S+ C C+ G+ C D+DECSQ P+PC
Sbjct: 2365 DECRMLAHLCAHGECINSLGSFRCHCQAGYTPDA-------TATTCLDMDECSQVPKPC- 2416
Query: 93 PNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNSM 152
CKN G + CSC G+ + +C D++EC TS CVN++
Sbjct: 2417 -TFLCKNTKGSFLCSCPRGYLL---------EEDGRTCKDLDEC-TSRQHNCQFLCVNTV 2465
Query: 153 GSYSCSCQVGFISRNSTCEDVDEC-ADPRACPEHATCNNTVGNYSCFCNPGFES-SSGHL 210
G+++C C GF + C D DEC A P C H C+NT G++ C C+ GF SSGH
Sbjct: 2466 GAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGH- 2524
Query: 211 SFQGLKASCEDIDECTEMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDID 270
CED++EC C N G Y C+C GF + Q +C D +
Sbjct: 2525 -------GCEDVNECDGPHRCQHGCQNQLGGYRCSCPQGFTQHS-------QWAQCVDEN 2570
Query: 271 ECRQDPSTCGPNSI----------------------------------------CTNALG 290
EC P TCG S C N G
Sbjct: 2571 ECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQEVDECAGRRGPCSYSCANTPG 2630
Query: 291 SYSCGCI--------------AGFHPNPEGSQKDGNFSCQRVLFKCK 323
+ CGC GF P P+ + ++CK
Sbjct: 2631 GFLCGCPQGYFRAGQGHCVSGLGFSPGPQDTPDKEELLSSEACYECK 2677
Score = 139 bits (350), Expect = 1e-32
Identities = 88/235 (37%), Positives = 117/235 (49%), Gaps = 35/235 (14%)
Query: 79 KDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLT 138
KD++EC P C + +C+N G + C+C GF+ +CTDI+EC
Sbjct: 985 KDVNECKVFPGLC-THGTCRNTVGSFHCACAGGFALDAQER---------NCTDIDECRI 1034
Query: 139 SSVCPEHSDCVNSMGSYSCSCQVGFISR---NSTCEDVDECA-DPRACPEHATCNNTVGN 194
S CVN+ GS+ C C G+ S C DVDECA DP C TC NT G+
Sbjct: 1035 SPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLC-RGGTCTNTDGS 1093
Query: 195 YSCFCNPGFESSSGHLSFQGLKASCEDIDECT---EMCPINSTCTNTPGSYFCTCHPGFA 251
Y C C PG E L+ +G +CEDIDEC+ +CP + C N G++ C+CH GF
Sbjct: 1094 YKCQCPPGHE-----LTAKG--TACEDIDECSLSDGLCP-HGQCVNVIGAFQCSCHAGFQ 1145
Query: 252 PSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEG 306
+ + QG C DI+ECR C + C N GSY C C G+ P+G
Sbjct: 1146 STPDR-----QG--CVDINECRVQNGGCDVH--CINTEGSYRCSCGQGYSLMPDG 1191
Score = 136 bits (343), Expect = 8e-32
Identities = 96/310 (30%), Positives = 130/310 (41%), Gaps = 53/310 (17%)
Query: 22 IRPTRKPNTKGNNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDI 81
+ P K N C ST+C C N S+ C CK GFL + G ++ C DI
Sbjct: 522 LSPDGKNCVDHNECATSTMC-VNGVCLNEDGSFSCLCKPGFLLAPGGHY-------CMDI 573
Query: 82 DECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINE------ 135
DEC Q+P C N C N G ++C CL G + T +C E
Sbjct: 574 DEC-QTPGIC-VNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCAR 631
Query: 136 ----CLTSSVC----PEHS---DC----VNSMGSYSCSCQVGFISRNSTCEDVDECA-DP 179
+T S C P+H C + C G + + D++ECA DP
Sbjct: 632 PFPGTVTKSECCCANPDHGFGEPCQLCPAKDSAEFQALCSSG-LGITTDGRDINECALDP 690
Query: 180 RACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECT--EMCPINSTCTN 237
C + C N G+Y C CN G+E+ + C D+DEC + N C N
Sbjct: 691 EVCA-NGVCENLRGSYRCVCNLGYEAGASG-------KDCTDVDECALNSLLCDNGWCQN 742
Query: 238 TPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCI 297
+PGSY C+C PGF +F C+D+DEC P G +C N GSY+C C
Sbjct: 743 SPGSYSCSCPPGF-------HFWQDTEICKDVDECLSSPCVSG---VCRNLAGSYTCKCG 792
Query: 298 AGFHPNPEGS 307
G +P G+
Sbjct: 793 PGSRLDPSGT 802
Score = 136 bits (342), Expect = 1e-31
Identities = 97/308 (31%), Positives = 137/308 (44%), Gaps = 56/308 (18%)
Query: 32 GNNCRDSTLCPAY------ATCTNTVDSYYCACKQG-FLSSNGQ---NHFKDPGVRCKDI 81
G C D C ++ C NT S+ C C +G L ++G+ + +P D
Sbjct: 864 GVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDE 923
Query: 82 DECSQS-PQPCGPNSSCKNLSGRYKCSCLD-----------------GFSSPTGNDWVPG 123
DEC + P + C ++ + C GF+S D++ G
Sbjct: 924 DECGVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFAS---RDFLSG 980
Query: 124 KPGNFSCTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGFI--SRNSTCEDVDEC-ADPR 180
+P D+NEC H C N++GS+ C+C GF ++ C D+DEC P
Sbjct: 981 RP---FYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPD 1037
Query: 181 ACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTE---MCPINSTCTN 237
C + TC NT G++ C C PG+E SG + L +C D+DEC +C TCTN
Sbjct: 1038 LCGQ-GTCVNTPGSFECECFPGYE--SGFM----LMKNCMDVDECARDPLLCR-GGTCTN 1089
Query: 238 TPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCI 297
T GSY C C PG T +G C DIDEC C P+ C N +G++ C C
Sbjct: 1090 TDGSYKCQCPPGH-------ELTAKGTACEDIDECSLSDGLC-PHGQCVNVIGAFQCSCH 1141
Query: 298 AGFHPNPE 305
AGF P+
Sbjct: 1142 AGFQSTPD 1149
Score = 134 bits (338), Expect = 3e-31
Identities = 95/315 (30%), Positives = 130/315 (41%), Gaps = 57/315 (18%)
Query: 33 NNCRDSTLCPAYATCTNTVDSYYCACKQGF-LSSNGQNHFKDPGVRCKDIDECSQSPQPC 91
+ C + + TCTN+ S+ C C GF LS NG F C E + P
Sbjct: 1971 DECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPK 2030
Query: 92 GPNSSCKNLSGRYKCSCL----DGFSSPT-----------------GNDWVPGKPGNFSC 130
N++ + +C C +G+ P G+ VPG + S
Sbjct: 2031 AFNTT------KTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGP--DDSR 2082
Query: 131 TDINECLTSSVCPEHSDCVNSMGSYSCSCQVGFI--SRNSTCEDVDECADPRACPEHATC 188
D+NEC + + CVN+ GS+ C C G+ C D DEC+ C + TC
Sbjct: 2083 EDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQ-GTC 2141
Query: 189 NNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECT---EMCPINSTCTNTPGSYFCT 245
N +G + C C GFE GL +CEDIDEC+ +C C NT GSY CT
Sbjct: 2142 TNVIGGFECACADGFE--------PGLMMTCEDIDECSLNPLLCAFR--CHNTEGSYLCT 2191
Query: 246 CHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSI-CTNALGSYSCGCIAGFHPNP 304
C G+ + G CRD+DEC C + C N +G+++C C G P P
Sbjct: 2192 CPAGY-------TLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLP 2244
Query: 305 ---EGSQKDGNFSCQ 316
EG D Q
Sbjct: 2245 GSGEGCTDDNECHAQ 2259
Score = 134 bits (336), Expect = 5e-31
Identities = 92/321 (28%), Positives = 128/321 (39%), Gaps = 65/321 (20%)
Query: 33 NNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCG 92
N CR+ ++ C +T SY C C +GF +S Q C DIDEC + QPCG
Sbjct: 1807 NECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQT-------LCMDIDECDR--QPCG 1857
Query: 93 PNSSCKNLSGRYKCSCLDGFSSPTGNDWVP------------------GKPGNF------ 128
N +CKN+ G Y C C GF D V G+F
Sbjct: 1858 -NGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQD 1916
Query: 129 ---------SCTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGFISRNSTCEDVDECADP 179
+C D NECL+ + C N GS+ C C GF ++ C D+DEC++
Sbjct: 1917 GFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSDHCIDIDECSEE 1976
Query: 180 RACPEHATCNNTVGNYSCFCNPGFE-SSSGHLSFQGLKASCEDIDECTEMCPINSTCTNT 238
TC N+ G++ C C PGF S +GH F ++ C E + C + T
Sbjct: 1977 PNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGK-CSVPKAFNTT 2035
Query: 239 PGSYFCTCHPG--------FAPSNGQLNFTD-----------QGVECRDIDECRQDPSTC 279
C+ PG P G F + D++EC ++P C
Sbjct: 2036 KTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVC 2095
Query: 280 GPNSICTNALGSYSCGCIAGF 300
N +C N GS+ C C G+
Sbjct: 2096 -TNGVCVNTDGSFRCECPFGY 2115
Score = 133 bits (334), Expect = 8e-31
Identities = 78/228 (34%), Positives = 105/228 (46%), Gaps = 37/228 (16%)
Query: 32 GNNCRDSTLCPAYA-----TCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQ 86
G C+D C + C NTV ++ C C GF Q+H C D DECS
Sbjct: 2441 GRTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFT----QHH-----QACFDNDECSA 2491
Query: 87 SPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHS 146
P PCG + C N G ++C C GF+ + C D+NEC C +H
Sbjct: 2492 QPGPCGAHGHCHNTPGSFRCECHQGFTLVS---------SGHGCEDVNECDGPHRC-QHG 2541
Query: 147 DCVNSMGSYSCSCQVGFI--SRNSTCEDVDECA-DPRACPEHATCNNTVGNYSCFCNPGF 203
C N +G Y CSC GF S+ + C D +ECA P C A+C NT+G + C C GF
Sbjct: 2542 -CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGS-ASCRNTLGGFRCVCPSGF 2599
Query: 204 ESSSGHLSFQGLKASCEDIDECT-EMCPINSTCTNTPGSYFCTCHPGF 250
+ F C+++DEC P + +C NTPG + C C G+
Sbjct: 2600 D-------FDQALGGCQEVDECAGRRGPCSYSCANTPGGFLCGCPQGY 2640
Score = 131 bits (330), Expect = 2e-30
Identities = 81/246 (32%), Positives = 111/246 (45%), Gaps = 29/246 (11%)
Query: 80 DIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLT- 138
DIDEC + P C N C N G ++C C GF+ N + +C D++EC +
Sbjct: 1721 DIDECGEIPAICA-NGICINQIGSFRCECPAGFNY---NSIL------LACEDVDECGSR 1770
Query: 139 SSVCPEHSDCVNSMGSYSCSCQVGF-ISRNSTCEDVDECAD-PRACPEHATCNNTVGNYS 196
S C +++DC+N GSY C C G+ +S C +EC + P C H C +T G+Y
Sbjct: 1771 ESPCQQNADCINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVC-SHGDCMDTEGSYM 1829
Query: 197 CFCNPGFESSSGHLSFQGLKASCEDIDECTEMCPINSTCTNTPGSYFCTCHPGFAPSNGQ 256
C C+ GF++S+ + C DIDEC N TC N GSY C C PGF ++
Sbjct: 1830 CLCHRGFQASAD-------QTLCMDIDECDRQPCGNGTCKNIIGSYNCLCFPGFVVTHNG 1882
Query: 257 LNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQKDGNFSCQ 316
+C D DEC C N GS+ C C GF +G C
Sbjct: 1883 --------DCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECL 1934
Query: 317 RVLFKC 322
+ C
Sbjct: 1935 SLAGTC 1940
Score = 128 bits (321), Expect = 3e-29
Identities = 85/230 (36%), Positives = 104/230 (45%), Gaps = 34/230 (14%)
Query: 81 IDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSS 140
ID C C N C Y+C C G++ + C D++EC TSS
Sbjct: 409 IDICRHFTNLC-LNGRCLPTPSSYRCECNVGYTQDVRGE----------CIDVDEC-TSS 456
Query: 141 VCPEHSDCVNSMGSYSCSCQVGFISR--NSTCEDVDECADPRACPEHATCNNTVGNYSCF 198
C H DCVN G+Y C C GF + C DVDEC C NT G++ C
Sbjct: 457 PC-HHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCV 515
Query: 199 CNPGFESSSGHLSFQGLKASCEDIDEC--TEMCPINSTCTNTPGSYFCTCHPGFAPSNGQ 256
CN GFE LS G +C D +EC + MC +N C N GS+ C C PGF + G
Sbjct: 516 CNAGFE-----LSPDG--KNCVDHNECATSTMC-VNGVCLNEDGSFSCLCKPGFLLAPG- 566
Query: 257 LNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEG 306
G C DIDEC Q P C N CTN GS+ C C+ G +G
Sbjct: 567 ------GHYCMDIDEC-QTPGIC-VNGHCTNTEGSFRCQCLGGLAVGTDG 608
Score = 123 bits (309), Expect = 7e-28
Identities = 83/245 (33%), Positives = 110/245 (44%), Gaps = 36/245 (14%)
Query: 79 KDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLT 138
+DI+EC+ P+ C N C+NL G Y+C C G+ + G G CTD++EC
Sbjct: 681 RDINECALDPEVCA-NGVCENLRGSYRCVCNLGYEA--------GASGK-DCTDVDECAL 730
Query: 139 SSVCPEHSDCVNSMGSYSCSCQVGFISRNST--CEDVDECADPRACPEHATCNNTVGNYS 196
+S+ ++ C NS GSYSCSC GF T C+DVDEC C N G+Y+
Sbjct: 731 NSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSPCV--SGVCRNLAGSYT 788
Query: 197 CFCNPGFE-SSSGHLSFQGLKASC-EDIDECTEMCPIN-------STCTNTPGSYF---- 243
C C PG SG K +C I E C +N S C T G+ +
Sbjct: 789 CKCGPGSRLDPSGTFCLDSTKGTCWLKIQE--SRCEVNLQGASLRSECCATLGAAWGSPC 846
Query: 244 --CTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFH 301
C P A ++ GV C D++EC P C PN C N GS+ C C G
Sbjct: 847 ERCEIDPACARGFARMT----GVTCDDVNECESFPGVC-PNGRCVNTAGSFRCECPEGLM 901
Query: 302 PNPEG 306
+ G
Sbjct: 902 LDASG 906
Score = 123 bits (308), Expect = 9e-28
Identities = 96/326 (29%), Positives = 130/326 (39%), Gaps = 74/326 (22%)
Query: 32 GNNCRDSTLCPAY------ATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECS 85
G C D C A C NT S+ C C +GF S + EC
Sbjct: 2247 GEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPS-------------PTLTECH 2293
Query: 86 QSPQ-PCGPN---SSCKNLSG------RYKCSCLDGFSSPTGNDWVP------------- 122
Q PC + C++LS R +C C G + P
Sbjct: 2294 DIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPH 2353
Query: 123 GKPGNFSCTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGFI--SRNSTCEDVDECAD-P 179
G D++EC + H +C+NS+GS+ C CQ G+ + +TC D+DEC+ P
Sbjct: 2354 GSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVP 2413
Query: 180 RACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTEM---CPINSTCT 236
+ C C NT G++ C C G+ L G +C+D+DECT C C
Sbjct: 2414 KPCT--FLCKNTKGSFLCSCPRGYL-----LEEDG--RTCKDLDECTSRQHNCQF--LCV 2462
Query: 237 NTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGC 296
NT G++ C C PGF T C D DEC P CG + C N GS+ C C
Sbjct: 2463 NTVGAFTCRCPPGF---------TQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCEC 2513
Query: 297 IAGF------HPNPEGSQKDGNFSCQ 316
GF H + ++ DG CQ
Sbjct: 2514 HQGFTLVSSGHGCEDVNECDGPHRCQ 2539
Score = 122 bits (305), Expect = 2e-27
Identities = 77/221 (34%), Positives = 96/221 (43%), Gaps = 33/221 (14%)
Query: 35 CRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPN 94
CR T C T SY C C G+ +D C D+DEC+ SP G
Sbjct: 412 CRHFTNLCLNGRCLPTPSSYRCECNVGYT--------QDVRGECIDVDECTSSPCHHG-- 461
Query: 95 SSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNSMGS 154
C N+ G Y C C GF + P +C D++EC+ S CVN+ GS
Sbjct: 462 -DCVNIPGTYHCRCYPGFQAT---------PTRQACVDVDECIVSGGLCHLGRCVNTEGS 511
Query: 155 YSCSCQVGF--ISRNSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPGF-ESSSGHLS 211
+ C C GF C D +ECA C + C N G++SC C PGF + GH
Sbjct: 512 FQCVCNAGFELSPDGKNCVDHNECATSTMC-VNGVCLNEDGSFSCLCKPGFLLAPGGHY- 569
Query: 212 FQGLKASCEDIDEC-TEMCPINSTCTNTPGSYFCTCHPGFA 251
C DIDEC T +N CTNT GS+ C C G A
Sbjct: 570 -------CMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLA 603
Score = 117 bits (294), Expect = 4e-26
Identities = 84/280 (30%), Positives = 113/280 (40%), Gaps = 53/280 (18%)
Query: 57 ACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFS--- 113
AC +GF G V C D++EC P C PN C N +G ++C C +G
Sbjct: 854 ACARGFARMTG--------VTCDDVNECESFPGVC-PNGRCVNTAGSFRCECPEGLMLDA 904
Query: 114 ----------SPTGNDW--------VPGKPGNFSCTDINECLTSSVCPEHSDCVNSMGSY 155
P W +PGK C + C D + +
Sbjct: 905 SGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFAS 964
Query: 156 SCSCQVGFISRNSTC-----EDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHL 210
C +GF SR+ +DV+EC H TC NTVG++ C C GF
Sbjct: 965 LCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGF------- 1017
Query: 211 SFQGLKASCEDIDEC---TEMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECR 267
+ + +C DIDEC ++C TC NTPGS+ C C PG+ + C
Sbjct: 1018 ALDAQERNCTDIDECRISPDLCG-QGTCVNTPGSFECECFPGYESGFMLMK------NCM 1070
Query: 268 DIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGS 307
D+DEC +DP C CTN GSY C C G +G+
Sbjct: 1071 DVDECARDPLLC-RGGTCTNTDGSYKCQCPPGHELTAKGT 1109
Score = 117 bits (294), Expect = 4e-26
Identities = 88/285 (30%), Positives = 119/285 (41%), Gaps = 61/285 (21%)
Query: 79 KDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLT 138
+D+DEC C + C N G ++C C G++ +C D++EC
Sbjct: 2362 RDVDECRMLAHLCA-HGECINSLGSFRCHCQAGYTPDATAT---------TCLDMDEC-- 2409
Query: 139 SSVCPEHSD--CVNSMGSYSCSCQVGFISRNS--TCEDVDECADPRACPEHATCNNTVGN 194
S P+ C N+ GS+ CSC G++ TC+D+DEC R C NTVG
Sbjct: 2410 -SQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTS-RQHNCQFLCVNTVGA 2467
Query: 195 YSCFCNPGFESSSGHLSFQGLKASCEDIDECTEM---CPINSTCTNTPGSYFCTCHPGFA 251
++C C PGF +C D DEC+ C + C NTPGS+ C CH GF
Sbjct: 2468 FTCRCPPGFTQHH---------QACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFT 2518
Query: 252 PSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQ--- 308
G C D++EC P C C N LG Y C C GF + + +Q
Sbjct: 2519 -------LVSSGHGCEDVNEC-DGPHRCQHG--CQNQLGGYRCSCPQGFTQHSQWAQCVD 2568
Query: 309 ---------KDGNFSCQRVL--FKCKEDVIPDNKQIQQ----CQE 338
G+ SC+ L F+C V P Q CQE
Sbjct: 2569 ENECALSPPTCGSASCRNTLGGFRC---VCPSGFDFDQALGGCQE 2610
Score = 112 bits (280), Expect = 2e-24
Identities = 88/319 (27%), Positives = 126/319 (39%), Gaps = 51/319 (15%)
Query: 32 GNNCRDSTLCPA-----YATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVR--CKDIDEC 84
G NC D+ C TCTN + + CAC GF +PG+ C+DIDEC
Sbjct: 2121 GINCVDTDECSVGHPCGQGTCTNVIGGFECACADGF----------EPGLMMTCEDIDEC 2170
Query: 85 SQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSV-CP 143
S +P C C N G Y C+C G++ + C D++EC C
Sbjct: 2171 SLNPLLCA--FRCHNTEGSYLCTCPAGYTL---------REDGAMCRDVDECADGQQDCH 2219
Query: 144 EHS-DCVNSMGSYSCSCQVGFI---SRNSTCEDVDEC-ADPRACPEHATCNNTVGNYSCF 198
+C N +G+++C C G C D +EC A P C + C NT G++ C
Sbjct: 2220 ARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCV-NGRCVNTAGSFRCD 2278
Query: 199 CNPGFESSSGHLSFQGLKASCEDIDECTEMCPINSTCTNTPGSYFCTCHPG--------F 250
C+ GF+ S ++ + MC S+ + C C G
Sbjct: 2279 CDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCEL 2338
Query: 251 APSNGQLNF-------TDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPN 303
P G + + E RD+DECR C C N+LGS+ C C AG+ P+
Sbjct: 2339 CPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGE-CINSLGSFRCHCQAGYTPD 2397
Query: 304 PEGSQKDGNFSCQRVLFKC 322
+ C +V C
Sbjct: 2398 ATATTCLDMDECSQVPKPC 2416
Score = 100 bits (249), Expect = 6e-21
Identities = 81/292 (27%), Positives = 111/292 (38%), Gaps = 57/292 (19%)
Query: 79 KDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLT 138
+DIDEC + P C C N G ++C C G+ C DI+EC T
Sbjct: 1562 EDIDECQELPGLC-QGGDCVNTFGSFQCECPPGYHLSEHTR---------ICEDIDECST 1611
Query: 139 SSVCPEHSDCVNSMGSYSCSCQVGFISRNSTCEDVDECADPR--ACPEH--ATCNN---- 190
S C N++G+Y+C C ++ N + C D R C H TC N
Sbjct: 1612 HSGICGPGTCYNTLGNYTCVCPAEYLQVNGG----NNCMDMRKSVCFRHYNGTCQNELAF 1667
Query: 191 TVGNYSCFCN-------------------PGFESSSGHLSFQGLKASCE-----DIDECT 226
V C C+ P ++ G+ + G DIDEC
Sbjct: 1668 NVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQILCGNQA-PGFLTDIHTGKPLDIDECG 1726
Query: 227 EMCPI--NSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSI 284
E+ I N C N GS+ C C GF N+ + C D+DEC S C N+
Sbjct: 1727 EIPAICANGICINQIGSFRCECPAGF-------NYNSILLACEDVDECGSRESPCQQNAD 1779
Query: 285 CTNALGSYSCGCIAGFHPNPEGSQKDGNFSCQRVLFKCKEDVIPDNKQIQQC 336
C N GSY C C G+ +P G+ G C+ + C D + C
Sbjct: 1780 CINIPGSYRCKCTRGYKLSPGGACV-GRNECREIPNVCSHGDCMDTEGSYMC 1830
Score = 90.5 bits (223), Expect = 6e-18
Identities = 78/264 (29%), Positives = 106/264 (40%), Gaps = 57/264 (21%)
Query: 33 NNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCG 92
+ C LC A+ +C N + C C G+ G G C DI+EC+ P C
Sbjct: 1406 DECAQGNLC-AFGSCENLPGMFRCICNGGYELDRG-------GGNCTDINECA-DPVNC- 1455
Query: 93 PNSSCKNLSGRYKCSCLDGFS-SPTGNDWVPGKPGN------------FSCT-DINECLT 138
N C N G Y CSC F +P+G V + GN SC+ +I +T
Sbjct: 1456 INGVCINTPGSYLCSCPQDFELNPSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVT 1515
Query: 139 SSVCPEHSDCVNSMGSYSCSCQV-----------------GFISRNST--CEDVDECADP 179
+ C C + ++ C++ GF T ED+DEC +
Sbjct: 1516 RASC-----CCSLGRAWGNPCELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQEL 1570
Query: 180 RACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTEMCPI--NSTCTN 237
+ C NT G++ C C PG+ HLS CEDIDEC+ I TC N
Sbjct: 1571 PGLCQGGDCVNTFGSFQCECPPGY-----HLSEH--TRICEDIDECSTHSGICGPGTCYN 1623
Query: 238 TPGSYFCTCHPGFAPSNGQLNFTD 261
T G+Y C C + NG N D
Sbjct: 1624 TLGNYTCVCPAEYLQVNGGNNCMD 1647
Score = 88.2 bits (217), Expect = 3e-17
Identities = 88/345 (25%), Positives = 124/345 (35%), Gaps = 84/345 (24%)
Query: 28 PNTKGNNCRDSTLCPAY------ATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDI 81
PN C+D C A +C N V S++C C G + D C+D
Sbjct: 238 PNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVG-------HRLSDSSAACEDY 290
Query: 82 DECSQSPQPCGPNSSCKNLSGRY---KCSCLDG----------FSSPTGND--------- 119
+ G + +L+G Y +C C G P G++
Sbjct: 291 RAGACFSVLFGGRCA-GDLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCAQR 349
Query: 120 --WVPGKPG------NFSCTDINECL-TSSVCPEHSDCVNSMGSYSCSCQVGFISRNSTC 170
+PG PG F + L + + P SD + +G + N T
Sbjct: 350 LPLLPGHPGLFPGLLGFGSNGMGPPLGPARLNPHGSDARGIPSLGPGNSNIGTATLNQT- 408
Query: 171 EDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTEMCP 230
+D C + C T +Y C CN G+ Q ++ C D+DECT
Sbjct: 409 --IDICRHFTNLCLNGRCLPTPSSYRCECNVGYT--------QDVRGECIDVDECTSSPC 458
Query: 231 INSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALG 290
+ C N PG+Y C C+PGF Q T Q C D+DEC C C N G
Sbjct: 459 HHGDCVNIPGTYHCRCYPGF-----QATPTRQA--CVDVDECIVSGGLCHLGR-CVNTEG 510
Query: 291 SYSCGCIAGFHPNPEGS--------------------QKDGNFSC 315
S+ C C AGF +P+G +DG+FSC
Sbjct: 511 SFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSC 555
Score = 43.1 bits (100), Expect = 0.001
Identities = 70/294 (23%), Positives = 100/294 (34%), Gaps = 73/294 (24%)
Query: 86 QSPQPCGP--NSSC----KNLSGRYKC-------SCLDGFSSPTGNDWVPGKPGNFSCTD 132
Q P CG ++ C + GR +C +C +GF S +P +C D
Sbjct: 55 QGPNVCGSRFHAYCCPGWRTFPGRSQCVVPICRRACGEGFCS---------QPNLCTCAD 105
Query: 133 ---INECLTSSVCPEHSDCVN--SMGSYSCSCQVGFISR-------NSTCEDVDECADPR 180
C S C+N + SC CQ G+ + C + C P
Sbjct: 106 GTLAPSCGVSRGSGCSVSCMNGGTCRGASCLCQKGYTGTVCGQPICDRGCHNGGRCIGPN 165
Query: 181 ACP-----EHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKAS----CEDIDEC----TE 227
C C CF G E L+ GL + C + E
Sbjct: 166 RCACVYGFMGPQCERDYRTGPCFGQVGPEGCQHQLT--GLVCTKALCCATVGRAWGLPCE 223
Query: 228 MCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTN 287
+CP C GF P+ G C+D+DEC+ P C S C N
Sbjct: 224 LCPAQPH----------PCRRGFIPN------IHTGA-CQDVDECQAVPGLCQGGS-CVN 265
Query: 288 ALGSYSCGCIAGFHPNPEGSQKDGNF---SCQRVLF--KCKEDVIPDNKQIQQC 336
+GS+ C C G H + S ++ +C VLF +C D+ + Q C
Sbjct: 266 MVGSFHCRCPVG-HRLSDSSAACEDYRAGACFSVLFGGRCAGDLAGHYTRRQCC 318
>gi|24430141 fibrillin 1 precursor [Homo sapiens]
Length = 2871
Score = 171 bits (432), Expect = 4e-42
Identities = 98/289 (33%), Positives = 135/289 (46%), Gaps = 39/289 (13%)
Query: 22 IRPTRKPNTKGNNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDI 81
+ P ++ T + C D+ CTN Y C C GF++S C D+
Sbjct: 1229 LMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMK-------TCVDV 1281
Query: 82 DECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINEC-LTSS 140
+EC +P C + +C+N G + C C G+S GK G CTDINEC + +
Sbjct: 1282 NECDLNPNIC-LSGTCENTKGSFICHCDMGYS---------GKKGKTGCTDINECEIGAH 1331
Query: 141 VCPEHSDCVNSMGSYSCSCQVGFISRNSTCEDVDECAD-PRACPEHATCNNTVGNYSCFC 199
C +H+ C N+ GS+ CSC G+I C D+DEC++ C +HA C NT+G+Y C C
Sbjct: 1332 NCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLC 1391
Query: 200 NPGFESSSGHLSFQGLKASCEDIDECTEMCPI--NSTCTNTPGSYFCTCHPGFAPSNGQL 257
G + G +C D+DEC+E + N C N PG Y C C GF PS
Sbjct: 1392 KEG---------YTGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPS---- 1438
Query: 258 NFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEG 306
G C DIDEC P+ C C N G + C C G+ + G
Sbjct: 1439 ---ADGKACEDIDECSL-PNIC-VFGTCHNLPGLFRCECEIGYELDRSG 1482
Score = 166 bits (419), Expect = 1e-40
Identities = 92/262 (35%), Positives = 126/262 (48%), Gaps = 38/262 (14%)
Query: 46 TCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYK 105
TC NT S+ C C G+ G+ C DI+EC CG ++ C N +G +K
Sbjct: 1295 TCENTKGSFICHCDMGYSGKKGKTG-------CTDINECEIGAHNCGKHAVCTNTAGSFK 1347
Query: 106 CSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSS-VCPEHSDCVNSMGSYSCSCQVGFI 164
CSC G W+ CTD++EC + +C +H+DC N+MGSY C C+ G+
Sbjct: 1348 CSCSPG--------WIGD---GIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYT 1396
Query: 165 SRNSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDE 224
TC D+DEC++ + C N G Y C C+ GF S+ +CEDIDE
Sbjct: 1397 GDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSAD-------GKACEDIDE 1449
Query: 225 CT--EMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPN 282
C+ +C + TC N PG + C C G+ G C D++EC DP+TC
Sbjct: 1450 CSLPNIC-VFGTCHNLPGLFRCECEIGY-------ELDRSGGNCTDVNEC-LDPTTCISG 1500
Query: 283 SICTNALGSYSCGCIAGFHPNP 304
+ C N GSY C C F NP
Sbjct: 1501 N-CVNTPGSYICDCPPDFELNP 1521
Score = 163 bits (412), Expect = 8e-40
Identities = 98/273 (35%), Positives = 129/273 (47%), Gaps = 45/273 (16%)
Query: 36 RDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVR-CKDIDECSQSPQPCGPN 94
RD LC C NT SY C C G H P + C DI+EC S C PN
Sbjct: 1119 RDPLLCRG-GVCHNTEGSYRCECPPG--------HQLSPNISACIDINECELSAHLC-PN 1168
Query: 95 SSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINEC-LTSSVCPEHSDCVNSMG 153
C NL G+Y+C+C G+ S P C DI+EC + + C + C NS G
Sbjct: 1169 GRCVNLIGKYQCACNPGYHST---------PDRLFCVDIDECSIMNGGC--ETFCTNSEG 1217
Query: 154 SYSCSCQVGF--ISRNSTCEDVDECAD-PRACPEHATCNNTVGNYSCFCNPGFESSSGHL 210
SY CSCQ GF + +C D+DEC D P C + C N G Y C C GF +S
Sbjct: 1218 SYECSCQPGFALMPDQRSCTDIDECEDNPNIC-DGGQCTNIPGEYRCLCYDGFMASED-- 1274
Query: 211 SFQGLKASCEDIDEC---TEMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECR 267
+C D++EC +C ++ TC NT GS+ C C G++ G+ C
Sbjct: 1275 -----MKTCVDVNECDLNPNIC-LSGTCENTKGSFICHCDMGYSGKKGKTG-------CT 1321
Query: 268 DIDECRQDPSTCGPNSICTNALGSYSCGCIAGF 300
DI+EC CG +++CTN GS+ C C G+
Sbjct: 1322 DINECEIGAHNCGKHAVCTNTAGSFKCSCSPGW 1354
Score = 160 bits (406), Expect = 4e-39
Identities = 101/273 (36%), Positives = 128/273 (46%), Gaps = 38/273 (13%)
Query: 33 NNCRDSTLCPAYATCTNTVDSYYCACKQGF-LSSNGQNHFKDPGVRCKDIDECSQSPQPC 91
N C+ + C NT+ S+ C C GF L S +N C DIDEC SP C
Sbjct: 1030 NECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERN--------CTDIDECRISPDLC 1081
Query: 92 GPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNS 151
G C N G ++C C +G+ S G +C DI+EC + C N+
Sbjct: 1082 G-RGQCVNTPGDFECKCDEGYES--------GFMMMKNCMDIDECQRDPLLCRGGVCHNT 1132
Query: 152 MGSYSCSCQVGF-ISRN-STCEDVDECA-DPRACPEHATCNNTVGNYSCFCNPGFESSSG 208
GSY C C G +S N S C D++EC CP + C N +G Y C CNPG+ S+
Sbjct: 1133 EGSYRCECPPGHQLSPNISACIDINECELSAHLCP-NGRCVNLIGKYQCACNPGYHSTPD 1191
Query: 209 HLSFQGLKASCEDIDECTEM-CPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECR 267
L C DIDEC+ M + CTN+ GSY C+C PGFA Q + C
Sbjct: 1192 RL-------FCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRS-------CT 1237
Query: 268 DIDECRQDPSTCGPNSICTNALGSYSCGCIAGF 300
DIDEC +P+ C CTN G Y C C GF
Sbjct: 1238 DIDECEDNPNICDGGQ-CTNIPGEYRCLCYDGF 1269
Score = 157 bits (398), Expect = 3e-38
Identities = 91/269 (33%), Positives = 129/269 (47%), Gaps = 44/269 (16%)
Query: 41 CPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNL 100
C +A CTNT S+ C+C G++ G++C D+DECS C ++ CKN
Sbjct: 1333 CGKHAVCTNTAGSFKCSCSPGWIGD---------GIKCTDLDECSNGTHMCSQHADCKNT 1383
Query: 101 SGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNSMGSYSCSCQ 160
G Y+C C +G+ TG+ F+CTD++EC + + C+N+ G Y C C
Sbjct: 1384 MGSYRCLCKEGY---TGD--------GFTCTDLDECSENLNLCGNGQCLNAPGGYRCECD 1432
Query: 161 VGFI--SRNSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFE-SSSGHLSFQGLKA 217
+GF+ + CED+DEC+ P C TC+N G + C C G+E SG
Sbjct: 1433 MGFVPSADGKACEDIDECSLPNIC-VFGTCHNLPGLFRCECEIGYELDRSG--------G 1483
Query: 218 SCEDIDECTEMCP-INSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDP 276
+C D++EC + I+ C NTPGSY C C P F +LN T G C D
Sbjct: 1484 NCTDVNECLDPTTCISGNCVNTPGSYICDCPPDF-----ELNPTRVGCVDTRSGNCYLDI 1538
Query: 277 STCGPN--SICTNALG----SYSCGCIAG 299
G N + C+N +G SC C G
Sbjct: 1539 RPRGDNGDTACSNEIGVGVSKASCCCSLG 1567
Score = 153 bits (386), Expect = 8e-37
Identities = 98/282 (34%), Positives = 134/282 (47%), Gaps = 49/282 (17%)
Query: 33 NNCRDSTLCPAYATCTNTVDSYYCACKQGF-LSSNGQNHFKDPGVRCKDIDECSQSPQPC 91
+ C++ +C A C NT SY C CK G+ +S GQ C D +EC + P C
Sbjct: 1810 DECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTGQ---------CNDRNECQEIPNIC 1860
Query: 92 GPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNS 151
+ C + G + C C GF + ND C DINEC + + C N+
Sbjct: 1861 S-HGQCIDTVGSFYCLCHTGFKT---ND------DQTMCLDINECERDAC--GNGTCRNT 1908
Query: 152 MGSYSCSCQVGFI-SRNSTCEDVDECADPRA--CPEHATCNNTVGNYSCFCNPGFESSSG 208
+GS++C C GFI S N+ C DVDECA C + C NTVG++ C CN G+E +
Sbjct: 1909 IGSFNCRCNHGFILSHNNDCIDVDECASGNGNLC-RNGQCINTVGSFQCQCNEGYEVAPD 1967
Query: 209 HLSFQGLKASCEDIDECT----EMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGV 264
+C DI+EC + P TC N GSY C C PG++ N
Sbjct: 1968 G-------RTCVDINECLLEPRKCAP--GTCQNLDGSYRCICPPGYSLQN---------E 2009
Query: 265 ECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEG 306
+C DIDEC ++P C + C+N GS+ C C GF + G
Sbjct: 2010 KCEDIDECVEEPEICALGT-CSNTEGSFKCLCPEGFSLSSSG 2050
Score = 150 bits (379), Expect = 5e-36
Identities = 91/258 (35%), Positives = 124/258 (48%), Gaps = 42/258 (16%)
Query: 47 CTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKC 106
C N SY+C CK G+ G C D++EC+Q+P+PC N CKN G Y+C
Sbjct: 2418 CVNDRGSYHCICKTGYTPDI-------TGTSCVDLNECNQAPKPC--NFICKNTEGSYQC 2468
Query: 107 SCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSD---CVNSMGSYSCSCQVGF 163
SC G+ + + G SC D++EC T +H+ CVN++G ++C C GF
Sbjct: 2469 SCPKGY--------ILQEDGR-SCKDLDECATK----QHNCQFLCVNTIGGFTCKCPPGF 2515
Query: 164 ISRNSTCEDVDEC-ADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDI 222
+++C D +EC +D C C NT G+++C C GF S +SCED+
Sbjct: 2516 TQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGF-------SLDQTGSSCEDV 2568
Query: 223 DECTEMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPN 282
DEC C N G Y C+C G+ Q +C D +EC CG
Sbjct: 2569 DECEGNHRCQHGCQNIIGGYRCSCPQGYLQHY-------QWNQCVDENEC-LSAHICGGA 2620
Query: 283 SICTNALGSYSCGCIAGF 300
S C N LGSY C C AGF
Sbjct: 2621 S-CHNTLGSYKCMCPAGF 2637
Score = 150 bits (378), Expect = 7e-36
Identities = 91/275 (33%), Positives = 128/275 (46%), Gaps = 45/275 (16%)
Query: 33 NNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCG 92
+ CR+ C N V S+ C C GF + D + C+DIDEC P C
Sbjct: 1768 DECREIPGVCENGVCINMVGSFRCECPVGFF-------YNDKLLVCEDIDECQNGPV-CQ 1819
Query: 93 PNSSCKNLSGRYKCSCLDGFS-SPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNS 151
N+ C N +G Y+C C G+ + TG C D NEC H C+++
Sbjct: 1820 RNAECINTAGSYRCDCKPGYRFTSTGQ-----------CNDRNECQEIPNICSHGQCIDT 1868
Query: 152 MGSYSCSCQVGFISRN--STCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGH 209
+GS+ C C GF + + + C D++EC + AC + TC NT+G+++C CN GF S +
Sbjct: 1869 VGSFYCLCHTGFKTNDDQTMCLDINEC-ERDACG-NGTCRNTIGSFNCRCNHGFILSHNN 1926
Query: 210 LSFQGLKASCEDIDECT----EMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVE 265
C D+DEC +C N C NT GS+ C C+ G+ G
Sbjct: 1927 --------DCIDVDECASGNGNLCR-NGQCINTVGSFQCQCNEGY-------EVAPDGRT 1970
Query: 266 CRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGF 300
C DI+EC +P C P + C N GSY C C G+
Sbjct: 1971 CVDINECLLEPRKCAPGT-CQNLDGSYRCICPPGY 2004
Score = 145 bits (365), Expect = 2e-34
Identities = 79/229 (34%), Positives = 113/229 (49%), Gaps = 28/229 (12%)
Query: 80 DIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTS 139
DIDEC + P C N C N+ G ++C C GF ND + C DI+EC
Sbjct: 1766 DIDECREIPGVC-ENGVCINMVGSFRCECPVGFFY---NDKL------LVCEDIDECQNG 1815
Query: 140 SVCPEHSDCVNSMGSYSCSCQVGF-ISRNSTCEDVDECAD-PRACPEHATCNNTVGNYSC 197
VC +++C+N+ GSY C C+ G+ + C D +EC + P C H C +TVG++ C
Sbjct: 1816 PVCQRNAECINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNIC-SHGQCIDTVGSFYC 1874
Query: 198 FCNPGFESSSGHLSFQGLKASCEDIDECTEMCPINSTCTNTPGSYFCTCHPGFAPSNGQL 257
C+ GF+++ + C DI+EC N TC NT GS+ C C+ GF S+
Sbjct: 1875 LCHTGFKTNDD-------QTMCLDINECERDACGNGTCRNTIGSFNCRCNHGFILSHNN- 1926
Query: 258 NFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEG 306
+C D+DEC N C N +GS+ C C G+ P+G
Sbjct: 1927 -------DCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDG 1968
Score = 144 bits (362), Expect = 5e-34
Identities = 122/456 (26%), Positives = 178/456 (39%), Gaps = 91/456 (19%)
Query: 28 PNTKGNNCRDSTLC-----PAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDID 82
P+ G +C D C P C NT SY C+C +G++ ++ G CKD+D
Sbjct: 2435 PDITGTSCVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYI-------LQEDGRSCKDLD 2487
Query: 83 ECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTS-SV 141
EC+ C C N G + C C GF+ + SC D NEC + ++
Sbjct: 2488 ECATKQHNC--QFLCVNTIGGFTCKCPPGFTQH-----------HTSCIDNNECTSDINL 2534
Query: 142 CPEHSDCVNSMGSYSCSCQVGFI--SRNSTCEDVDECADPRACPEHATCNNTVGNYSCFC 199
C C N+ GS++C CQ GF S+CEDVDEC C +H C N +G Y C C
Sbjct: 2535 CGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHRC-QHG-CQNIIGGYRCSC 2592
Query: 200 NPGFESSSGHLSFQGLKASCEDIDEC--TEMCPINSTCTNTPGSYFCTCHPGFAPSNGQL 257
G+ H + C D +EC +C ++C NT GSY C C GF
Sbjct: 2593 PQGYLQ---HYQWN----QCVDENECLSAHICG-GASCHNTLGSYKCMCPAGF------- 2637
Query: 258 NFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGF---------------HP 302
+ C+DI+EC + C C+N G Y CGC G+
Sbjct: 2638 QYEQFSGGCQDINECGSAQAPCSYG--CSNTEGGYLCGCPPGYFRIGQGHCVSGMGMGRG 2695
Query: 303 NPE---GSQKDGNFSCQRVLFKCKEDVIP------------DNKQIQQCQEGTAVKPAYV 347
NPE + D N ++CK + P D I+ Q T +
Sbjct: 2696 NPEPPVSGEMDDNSLSPEACYECKINGYPKRGRKRRSTNETDASNIED-QSETEANVSLA 2754
Query: 348 SFCAQINNIFSVLDKVCENKTTVVSLKNTTESFVPVLKQISTWTKFTKEETSSLATVFLE 407
S+ + IF+ NK ++ L +P L ++ ++ E + +
Sbjct: 2755 SWDVEKTAIFAFNISHVSNKVRILEL-------LPALTTLTNHNRYLIESGNEDGFFKIN 2807
Query: 408 SVESMTLASFWKPSANITPAVRTEYLDIESKVINKE 443
E ++ F K P T L I S + K+
Sbjct: 2808 QKEGISYLHFTKKK----PVAGTYSLQISSTPLYKK 2839
Score = 142 bits (358), Expect = 1e-33
Identities = 109/369 (29%), Positives = 141/369 (38%), Gaps = 101/369 (27%)
Query: 27 KPNTKGNNCRDSTLCPAYA----TCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDID 82
K N C D C A TC NT+ S+ C C GF+ S+ + C D+D
Sbjct: 1881 KTNDDQTMCLDINECERDACGNGTCRNTIGSFNCRCNHGFILSHNND--------CIDVD 1932
Query: 83 ECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVC 142
EC+ N C N G ++C C +G+ P +C DINECL
Sbjct: 1933 ECASGNGNLCRNGQCINTVGSFQCQCNEGYEVA---------PDGRTCVDINECLLEPRK 1983
Query: 143 PEHSDCVNSMGSYSCSCQVGFISRNSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPG 202
C N GSY C C G+ +N CED+DEC + TC+NT G++ C C G
Sbjct: 1984 CAPGTCQNLDGSYRCICPPGYSLQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEG 2043
Query: 203 FE-SSSG-----------HLSFQGLKAS------------------------CE----DI 222
F SSSG + F+G K S CE +
Sbjct: 2044 FSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEP 2103
Query: 223 DEC-TEMCPINS-------------------------TCTNTPGSYFCTCHPGFAPSNGQ 256
DE ++CP S C NT GSY C C G+ +
Sbjct: 2104 DEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYILA--- 2160
Query: 257 LNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQKDGNFSCQ 316
G EC D DEC + CG N C N +G + C C GF P P + +D N Q
Sbjct: 2161 ------GNECVDTDECSVG-NPCG-NGTCKNVIGGFECTCEEGFEPGPMMTCEDINECAQ 2212
Query: 317 RVL---FKC 322
L F+C
Sbjct: 2213 NPLLCAFRC 2221
Score = 136 bits (342), Expect = 1e-31
Identities = 83/234 (35%), Positives = 109/234 (46%), Gaps = 35/234 (14%)
Query: 79 KDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLT 138
KDI+EC P C + C+N G +KC C GF+ + +CTDI+EC
Sbjct: 1027 KDINECKMIPSLC-THGKCRNTIGSFKCRCDSGFALDSEER---------NCTDIDECRI 1076
Query: 139 SSVCPEHSDCVNSMGSYSCSCQVGFIS---RNSTCEDVDECA-DPRACPEHATCNNTVGN 194
S CVN+ G + C C G+ S C D+DEC DP C C+NT G+
Sbjct: 1077 SPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLC-RGGVCHNTEGS 1135
Query: 195 YSCFCNPGFESSSGHLSFQGLKASCEDIDEC---TEMCPINSTCTNTPGSYFCTCHPGFA 251
Y C C PG + S ++C DI+EC +CP N C N G Y C C+PG+
Sbjct: 1136 YRCECPPGHQLSPNI-------SACIDINECELSAHLCP-NGRCVNLIGKYQCACNPGY- 1186
Query: 252 PSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPE 305
+ T + C DIDEC C + CTN+ GSY C C GF P+
Sbjct: 1187 ------HSTPDRLFCVDIDECSIMNGGC--ETFCTNSEGSYECSCQPGFALMPD 1232
Score = 135 bits (340), Expect = 2e-31
Identities = 94/308 (30%), Positives = 131/308 (42%), Gaps = 50/308 (16%)
Query: 33 NNCRDSTLCPAYATCTNTVDSYYCACKQGF-LSSNGQN---------HFKDPGVRCKDID 82
+ C + A TC+NT S+ C C +GF LSS+G+ + K G +C
Sbjct: 2015 DECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPK 2074
Query: 83 ECSQSPQPCGPNSSCKNLSGRY---KCSCL-----DGFSS--PTGNDWVPGKPGNFSCTD 132
+ S Q C C L G C + F P G+ + G S D
Sbjct: 2075 SRNHSKQEC-----CCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDD--SAVD 2127
Query: 133 INECLTSSVCPEHSDCVNSMGSYSCSCQVGFISRNSTCEDVDECADPRACPEHATCNNTV 192
++EC VC +H C+N+ GSY C C G+I + C D DEC+ C + TC N +
Sbjct: 2128 MDECKEPDVC-KHGQCINTDGSYRCECPFGYILAGNECVDTDECSVGNPC-GNGTCKNVI 2185
Query: 193 GNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTE---MCPINSTCTNTPGSYFCTCHPG 249
G + C C GFE G +CEDI+EC + +C C NT GSY C C G
Sbjct: 2186 GGFECTCEEGFE--------PGPMMTCEDINECAQNPLLCAFR--CVNTYGSYECKCPVG 2235
Query: 250 FAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSI-CTNALGSYSCGCIAGFHPNPEGSQ 308
+ + C+D DEC + C + C N +G+Y C C G+ P+G
Sbjct: 2236 YV-------LREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEG 2288
Query: 309 KDGNFSCQ 316
CQ
Sbjct: 2289 CVDENECQ 2296
Score = 134 bits (336), Expect = 5e-31
Identities = 97/321 (30%), Positives = 133/321 (41%), Gaps = 69/321 (21%)
Query: 33 NNCRDST-LCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPC 91
+ C + T +C +A C NT+ SY C CK+G+ G C D+DECS++ C
Sbjct: 1365 DECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGD---------GFTCTDLDECSENLNLC 1415
Query: 92 GPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNS 151
G N C N G Y+C C GF VP G +C DI+EC ++C C N
Sbjct: 1416 G-NGQCLNAPGGYRCECDMGF--------VPSADGK-ACEDIDECSLPNIC-VFGTCHNL 1464
Query: 152 MGSYSCSCQVGF-ISRN-STCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFE----- 204
G + C C++G+ + R+ C DV+EC DP C C NT G+Y C C P FE
Sbjct: 1465 PGLFRCECEIGYELDRSGGNCTDVNECLDPTTCIS-GNCVNTPGSYICDCPPDFELNPTR 1523
Query: 205 ------------------------SSSGHLSFQGLKASC-----EDIDECTEMCPINSTC 235
+ S + KASC + EMCP +T
Sbjct: 1524 VGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNT- 1582
Query: 236 TNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCG 295
+ C GF P+ V DIDEC++ P C C N GS+ C
Sbjct: 1583 --SEYKILCPGGEGFRPN-------PITVILEDIDECQELPGLC-QGGKCINTFGSFQCR 1632
Query: 296 CIAGFHPNPEGSQKDGNFSCQ 316
C G++ N + D C+
Sbjct: 1633 CPTGYYLNEDTRVCDDVNECE 1653
Score = 128 bits (322), Expect = 2e-29
Identities = 98/328 (29%), Positives = 133/328 (40%), Gaps = 68/328 (20%)
Query: 26 RKPNTKG----NNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDI 81
R+P+ +G N C+ C NT SY C C GF +S Q+ C D
Sbjct: 2282 RRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQD-------ECLDN 2334
Query: 82 DE----CSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVP--------------- 122
E C SS +N + +C C DG G W P
Sbjct: 2335 REGYCFTEVLQNMCQIGSSNRNPVTKSEC-CCDG-----GRGWGPHCEICPFQGTVAFKK 2388
Query: 123 ----GKPGNFSCTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGFIS--RNSTCEDVDEC 176
G+ + DI+EC + +CVN GSY C C+ G+ ++C D++EC
Sbjct: 2389 LCPHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNEC 2448
Query: 177 AD-PRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDEC-TEMCPINST 234
P+ C + C NT G+Y C C G+ Q SC+D+DEC T+
Sbjct: 2449 NQAPKPC--NFICKNTEGSYQCSCPKGY-------ILQEDGRSCKDLDECATKQHNCQFL 2499
Query: 235 CTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSC 294
C NT G + C C PG FT C D +EC D + CG IC N GS++C
Sbjct: 2500 CVNTIGGFTCKCPPG---------FTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTC 2550
Query: 295 GCIAGFHPNPEGS------QKDGNFSCQ 316
C GF + GS + +GN CQ
Sbjct: 2551 ECQRGFSLDQTGSSCEDVDECEGNHRCQ 2578
Score = 120 bits (300), Expect = 7e-27
Identities = 93/295 (31%), Positives = 119/295 (40%), Gaps = 59/295 (20%)
Query: 32 GNNCRDSTLCPAYATCTNTV-----DSYYCACKQGF-LSSNGQNHFKDPGVRCKDIDECS 85
G NC D C C N + S+ C CK GF L+S+G+ CKDI+EC
Sbjct: 567 GKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRY--------CKDINEC- 617
Query: 86 QSPQPCGPNSSCKNLSGRYKCSCLDGFS--------------SPTGNDWVPG---KPGNF 128
++P C N C N G Y+C C G + S + G KP
Sbjct: 618 ETPGIC-MNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFG 676
Query: 129 SCTDINECLTSSVCPEHSDC----VNSMGSYSCSCQVGFISRNSTCEDVDECA-DPRACP 183
+ T C S+ C + Y C G S D++ECA DP CP
Sbjct: 677 AVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSG-PGMTSAGSDINECALDPDICP 735
Query: 184 EHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDEC--TEMCPINSTCTNTPGS 241
+ C N G Y C CN G+E S +C DI+EC + N C NTPGS
Sbjct: 736 -NGICENLRGTYKCICNSGYEVDS-------TGKNCVDINECVLNSLLCDNGQCRNTPGS 787
Query: 242 YFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGC 296
+ CTC GF + C DIDEC P N +C N+ GS+ C C
Sbjct: 788 FVCTCPKGFI-------YKPDLKTCEDIDECESSPCI---NGVCKNSPGSFICEC 832
Score = 118 bits (296), Expect = 2e-26
Identities = 73/209 (34%), Positives = 98/209 (46%), Gaps = 33/209 (15%)
Query: 47 CTNTVDSYYCACKQGF-LSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYK 105
C T S C C +GF L G+ C D+DEC ++P G C N G Y
Sbjct: 465 CIPTPGSCRCECNKGFQLDLRGE---------CIDVDECEKNPCAGG---ECINNQGSYT 512
Query: 106 CSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGF-I 164
C C G+ S C DI+ECL + + C+N+ GS+ C C GF +
Sbjct: 513 CQCRAGYQSTLTRT---------ECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHV 563
Query: 165 SRN-STCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDID 223
+R+ CED+DEC+ C + C N G++ C C PGF+ +S C+DI+
Sbjct: 564 TRDGKNCEDMDECSIRNMC-LNGMCINEDGSFKCICKPGFQLASD-------GRYCKDIN 615
Query: 224 EC-TEMCPINSTCTNTPGSYFCTCHPGFA 251
EC T +N C NT GSY C C PG A
Sbjct: 616 ECETPGICMNGRCVNTDGSYRCECFPGLA 644
Score = 118 bits (295), Expect = 3e-26
Identities = 79/235 (33%), Positives = 118/235 (50%), Gaps = 32/235 (13%)
Query: 80 DIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTS 139
DI+EC+ P C PN C+NL G YKC C G+ + GK +C DINEC+ +
Sbjct: 723 DINECALDPDIC-PNGICENLRGTYKCICNSGYEVDS-----TGK----NCVDINECVLN 772
Query: 140 SVCPEHSDCVNSMGSYSCSCQVGFISRN--STCEDVDECADPRACPEHATCNNTVGNYSC 197
S+ ++ C N+ GS+ C+C GFI + TCED+DEC + C N+ G++ C
Sbjct: 773 SLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCI--NGVCKNSPGSFIC 830
Query: 198 FCNPGFESS---SGHLSFQGLKASCED--IDECTEM----CPINSTCTNTPGSYF---CT 245
C+ ES+ + + + +K +C ID E+ + S C ++ G+ + CT
Sbjct: 831 ECSS--ESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCT 888
Query: 246 -CHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAG 299
C P G+ +G +C DIDEC P C N +C N GS+ C C +G
Sbjct: 889 LCQ--VDPICGKGYSRIKGTQCEDIDECEVFPGVC-KNGLCVNTRGSFKCQCPSG 940
Score = 117 bits (293), Expect = 5e-26
Identities = 103/377 (27%), Positives = 156/377 (41%), Gaps = 72/377 (19%)
Query: 47 CTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKC 106
C N SY C C+ G+ S+ + C+DIDEC Q+ + C N C N G + C
Sbjct: 504 CINNQGSYTCQCRAGYQSTLTRTE-------CRDIDECLQNGRICN-NGRCINTDGSFHC 555
Query: 107 SCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGF--I 164
C GF GK +C D++EC ++C + C+N GS+ C C+ GF
Sbjct: 556 VCNAGFHVTRD-----GK----NCEDMDECSIRNMCL-NGMCINEDGSFKCICKPGFQLA 605
Query: 165 SRNSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESS----------------SG 208
S C+D++EC P C + C NT G+Y C C PG G
Sbjct: 606 SDGRYCKDINECETPGICM-NGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGG 664
Query: 209 HLSFQGLKASCEDIDECTEMCPINSTCTNTPGSYFCTCHPGFAPSNGQLN--------FT 260
+ Q +K + + +E C C +T ++ C P A ++ + T
Sbjct: 665 YKRGQCIKPLFGAVTK-SECC-----CASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMT 718
Query: 261 DQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQKDGNFSCQRVLF 320
G DI+EC DP C PN IC N G+Y C C +G+ + G +C +
Sbjct: 719 SAG---SDINECALDPDIC-PNGICENLRGTYKCICNSGYEVDSTGK------NCVDINE 768
Query: 321 KCKEDVIPDNKQIQQ--------CQEGTAVKPAYVSFCAQINNIFS--VLDKVCENKTTV 370
++ DN Q + C +G KP + C I+ S ++ VC+N
Sbjct: 769 CVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPD-LKTCEDIDECESSPCINGVCKNSPGS 827
Query: 371 VSLKNTTESFVPVLKQI 387
+ ++ES + K I
Sbjct: 828 FICECSSESTLDPTKTI 844
Score = 111 bits (278), Expect = 3e-24
Identities = 102/389 (26%), Positives = 131/389 (33%), Gaps = 118/389 (30%)
Query: 30 TKGNNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDI--DECSQS 87
T N C D T C + C NT SY C C F V C D C
Sbjct: 1486 TDVNECLDPTTCIS-GNCVNTPGSYICDCPPDF-------ELNPTRVGCVDTRSGNCYLD 1537
Query: 88 PQPCGPN--SSCKNLSG----RYKCSCLDGFSSPTGNDWVPG------------------ 123
+P G N ++C N G + C C G + T + P
Sbjct: 1538 IRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRP 1597
Query: 124 KPGNFSCTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGFISRNST--CEDVDECADPRA 181
P DI+EC + C+N+ GS+ C C G+ T C+DV+EC P
Sbjct: 1598 NPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGI 1657
Query: 182 CPEHATCNNTVGNYSCFCNPGF-------------------------ESSSGHLSFQGLK 216
C TC NTVGNY+C C P + ++ G L F K
Sbjct: 1658 CGP-GTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTK 1716
Query: 217 ASC-------EDIDECTEMCPINST----------------------------------- 234
C ++ E CPI ST
Sbjct: 1717 KMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGV 1776
Query: 235 -----CTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNAL 289
C N GS+ C C GF + D+ + C DIDEC+ P C N+ C N
Sbjct: 1777 CENGVCINMVGSFRCECPVGFF-------YNDKLLVCEDIDECQNGP-VCQRNAECINTA 1828
Query: 290 GSYSCGCIAGFHPNPEGSQKDGNFSCQRV 318
GSY C C G+ G D N CQ +
Sbjct: 1829 GSYRCDCKPGYRFTSTGQCNDRN-ECQEI 1856
Score = 111 bits (278), Expect = 3e-24
Identities = 92/329 (27%), Positives = 135/329 (41%), Gaps = 87/329 (26%)
Query: 47 CTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKC 106
C NT S+ C C G+ + +D V C D++EC ++P CGP + C N G Y C
Sbjct: 1622 CINTFGSFQCRCPTGYYLN------EDTRV-CDDVNEC-ETPGICGPGT-CYNTVGNYTC 1672
Query: 107 SCLDGFSSPTGNDWVPGKPGNFSCTDINECLT-SSVCPEHSDC----VNSMGSYSCSCQV 161
C + G + +C D+ L + ++ C + +M C C
Sbjct: 1673 ICPPDYMQVNGGN---------NCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSY 1723
Query: 162 GFISR--NSTCE-------------------------------DVDECADPRACPEHATC 188
I R N CE D+DEC + E+ C
Sbjct: 1724 N-IGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCENGVC 1782
Query: 189 NNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTE--MCPINSTCTNTPGSYFCTC 246
N VG++ C C GF + L CEDIDEC +C N+ C NT GSY C C
Sbjct: 1783 INMVGSFRCECPVGFFYNDKLLV-------CEDIDECQNGPVCQRNAECINTAGSYRCDC 1835
Query: 247 HPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEG 306
PG+ FT G +C D +EC++ P+ C C + +GS+ C C GF N +
Sbjct: 1836 KPGY-------RFTSTG-QCNDRNECQEIPNICSHGQ-CIDTVGSFYCLCHTGFKTNDDQ 1886
Query: 307 S--------QKD--GNFSCQRVL--FKCK 323
+ ++D GN +C+ + F C+
Sbjct: 1887 TMCLDINECERDACGNGTCRNTIGSFNCR 1915
Score = 109 bits (273), Expect = 1e-23
Identities = 94/349 (26%), Positives = 129/349 (36%), Gaps = 78/349 (22%)
Query: 67 GQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFS-SPTGNDWVPGKP 125
G+ + + G +C+DIDEC P C N C N G +KC C G + TG
Sbjct: 897 GKGYSRIKGTQCEDIDECEVFPGVC-KNGLCVNTRGSFKCQCPSGMTLDATGR------- 948
Query: 126 GNFSCTDINECLTSSVCPEHSDCVNSMGSY----SCSCQVGFISRNSTCE---------- 171
C DI T + E +C + +C C VG CE
Sbjct: 949 ---ICLDIR-LETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEY 1004
Query: 172 -----------------------DVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSG 208
D++EC + H C NT+G++ C C+ GF S
Sbjct: 1005 EELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSE 1064
Query: 209 HLSFQGLKASCEDIDEC---TEMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVE 265
+ +C DIDEC ++C C NTPG + C C G+ +
Sbjct: 1065 -------ERNCTDIDECRISPDLCG-RGQCVNTPGDFECKCDEGYESGFMMMK------N 1110
Query: 266 CRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQKDGNFSCQRVLFKCKED 325
C DIDEC++DP C +C N GSY C C G +P S C+ C
Sbjct: 1111 CMDIDECQRDPLLC-RGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNG 1169
Query: 326 VIPDNKQIQQCQEGTAVKPAYVS-----FCAQINNIFSVLDKVCENKTT 369
+ QC A P Y S FC I+ S+++ CE T
Sbjct: 1170 RCVNLIGKYQC----ACNPGYHSTPDRLFCVDIDEC-SIMNGGCETFCT 1213
Score = 90.1 bits (222), Expect = 8e-18
Identities = 95/345 (27%), Positives = 119/345 (34%), Gaps = 68/345 (19%)
Query: 11 GCCV--MHSWEGHIRPTRKPNTKGNNCRDSTLCPAY------ATCTNTVDSYYCACKQGF 62
G C+ + S+E K N C D C CTNTV SY+C C GF
Sbjct: 260 GNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPPGF 319
Query: 63 LSSNGQNHFKDPGVRCKDIDECSQSPQPCG---PNSSCKN----LSGRYKCSCLDGFSSP 115
+S G RC D+ P C N C N + +C C G
Sbjct: 320 YTS-------PDGTRCIDV-----RPGYCYTALTNGRCSNQLPQSITKMQCCCDAGRCWS 367
Query: 116 TGNDWVPGKPGNFSCTDINE-CLTSSVCPEHSDC-VNSMGSYSCSCQV--GF-------I 164
G P + D N+ C V P + +G V GF +
Sbjct: 368 PGVTVAPEMCPIRATEDFNKLCSVPMVIPGRPEYPPPPLGPIPPVLPVPPGFPPGPQIPV 427
Query: 165 SRNSTCEDVDECADPRACPEHAT--------------CNNTVGNYSCFCNPGFESSSGHL 210
R PR P + T C T G+ C CN GF+
Sbjct: 428 PRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLCQNGRCIPTPGSCRCECNKGFQLD---- 483
Query: 211 SFQGLKASCEDIDECTEMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDID 270
L+ C D+DEC + C N GSY C C G+ T ECRDID
Sbjct: 484 ----LRGECIDVDECEKNPCAGGECINNQGSYTCQCRAGY-------QSTLTRTECRDID 532
Query: 271 ECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQKDGNFSC 315
EC Q+ C N C N GS+ C C AGFH +G + C
Sbjct: 533 ECLQNGRICN-NGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDEC 576
Score = 84.3 bits (207), Expect = 4e-16
Identities = 84/287 (29%), Positives = 108/287 (37%), Gaps = 66/287 (22%)
Query: 56 CACKQGFLS-SNGQNHFKDPGVRCKDIDECSQSPQPCGPN------------SSCKNLSG 102
C C G ++ S G + +RC + CS C S C N G
Sbjct: 100 CTCPSGQIAPSCGSRSIQHCNIRCMNGGSCSDDHCLCQKGYIGTHCGQPVCESGCLN-GG 158
Query: 103 RY----KCSCLDGFSSP-------TG-------NDWVPGKPGNFSCTDINECLTSSVCPE 144
R +C+C GF+ P TG N G+ CT C T
Sbjct: 159 RCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWG 218
Query: 145 HSDCVNSMGSYSCSCQVGFIS--RNSTCEDVDEC-ADPRACPEHATCNNTVGNYSCFCNP 201
H + C+ GFI R C+DVDEC A P C + C NTVG++ C C
Sbjct: 219 HP--CEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLC-QGGNCINTVGSFECKCPA 275
Query: 202 GFESSSGHLSFQGLKASCEDIDECTEMCPI--NSTCTNTPGSYFCTCHPGFAPSNGQLNF 259
G + + + CEDIDEC+ + I CTNT SYFC C PGF S
Sbjct: 276 GHKLNE-------VSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTS------ 322
Query: 260 TDQGVECRDIDECRQDPSTCG---PNSICTN----ALGSYSCGCIAG 299
G C D+ P C N C+N ++ C C AG
Sbjct: 323 -PDGTRCIDV-----RPGYCYTALTNGRCSNQLPQSITKMQCCCDAG 363
Score = 68.6 bits (166), Expect = 3e-11
Identities = 76/292 (26%), Positives = 106/292 (36%), Gaps = 87/292 (29%)
Query: 86 QSPQPCGP--NSSC----KNLSGRYKC-------SCLDGFSSPTGNDWVPGKPGNFSCTD 132
+ P CG N+ C K L G +C SC DGF S +P +C
Sbjct: 54 KGPNVCGSRYNAYCCPGWKTLPGGNQCIVPICRHSCGDGFCS---------RPNMCTCPS 104
Query: 133 ---INECLTSSVCPEHSDCVNSMGSYS---CSCQVGFISRN-------STCEDVDECADP 179
C + S+ + C+N GS S C CQ G+I + S C + C P
Sbjct: 105 GQIAPSCGSRSIQHCNIRCMNG-GSCSDDHCLCQKGYIGTHCGQPVCESGCLNGGRCVAP 163
Query: 180 RACP--------------EHATCNNTVGNYSC------------FCNPGFESSSGHLSF- 212
C C + N C C + GH
Sbjct: 164 NRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEM 223
Query: 213 ---------QGL-----KASCEDIDECTEMCPI--NSTCTNTPGSYFCTCHPGFAPSNGQ 256
+G +C+D+DEC + + C NT GS+ C C P+ +
Sbjct: 224 CPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKC-----PAGHK 278
Query: 257 LNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQ 308
LN Q +C DIDEC P C CTN + SY C C GF+ +P+G++
Sbjct: 279 LNEVSQ--KCEDIDECSTIPGICEGGE-CTNTVSSYFCKCPPGFYTSPDGTR 327
>gi|66346695 fibrillin 2 precursor [Homo sapiens]
Length = 2912
Score = 171 bits (432), Expect = 4e-42
Identities = 102/279 (36%), Positives = 134/279 (48%), Gaps = 42/279 (15%)
Query: 33 NNCR-DSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPC 91
N C +S +C + C NT S+ C C+ G+ G C D+DEC C
Sbjct: 1327 NECDLNSNIC-MFGECENTKGSFICHCQLGYSVKKGTTG-------CTDVDECEIGAHNC 1378
Query: 92 GPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGN-FSCTDINECLTSS-VCPEHSDCV 149
++SC N+ G +KCSC +G W+ GN C D++EC + C ++ CV
Sbjct: 1379 DMHASCLNIPGSFKCSCREG--------WI----GNGIKCIDLDECSNGTHQCSINAQCV 1426
Query: 150 NSMGSYSCSCQVGFISRNSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGH 209
N+ GSY C+C GF TC DVDECA+ E+ C N G Y C C GF +S
Sbjct: 1427 NTPGSYRCACSEGFTGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASD- 1485
Query: 210 LSFQGLKASCEDIDECT--EMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECR 267
SC+DIDEC+ +C + TC N PG + C C G+ +L+ T G C
Sbjct: 1486 ------SRSCQDIDECSFQNIC-VFGTCNNLPGMFHCICDDGY-----ELDRT--GGNCT 1531
Query: 268 DIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEG 306
DIDEC DP C N +C N G Y C C F NP G
Sbjct: 1532 DIDEC-ADPINC-VNGLCVNTPGRYECNCPPDFQLNPTG 1568
Score = 160 bits (406), Expect = 4e-39
Identities = 100/280 (35%), Positives = 131/280 (46%), Gaps = 44/280 (15%)
Query: 33 NNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCG 92
+ C++ A C N + S+ C C GF + D + C+DIDECS C
Sbjct: 1810 DECKEIPGICANGVCINQIGSFRCECPTGF-------SYNDLLLVCEDIDECSNGDNLCQ 1862
Query: 93 PNSSCKNLSGRYKCSCLDGFS-SPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNS 151
N+ C N G Y+C C GF SP G +C D NECL H CV+
Sbjct: 1863 RNADCINSPGSYRCECAAGFKLSPNG-----------ACVDRNECLEIPNVCSHGLCVDL 1911
Query: 152 MGSYSCSCQVGF-ISRNST-CEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGH 209
GSY C C GF S++ T C DVDEC + C + TC NTVG+Y+C C PGFE + +
Sbjct: 1912 QGSYQCICHNGFKASQDQTMCMDVDEC-ERHPC-GNGTCKNTVGSYNCLCYPGFELTHNN 1969
Query: 210 LSFQGLKASCEDIDECT----EMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVE 265
C DIDEC+ ++C N C N GS+ C C+ G+ T G
Sbjct: 1970 --------DCLDIDECSSFFGQVCR-NGRCFNEIGSFKCLCNEGY-------ELTPDGKN 2013
Query: 266 CRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPE 305
C D +EC P +C P + C N GS+ C C G+ E
Sbjct: 2014 CIDTNECVALPGSCSPGT-CQNLEGSFRCICPPGYEVKSE 2052
Score = 160 bits (404), Expect = 6e-39
Identities = 100/278 (35%), Positives = 135/278 (48%), Gaps = 45/278 (16%)
Query: 30 TKGNNCRDSTLCPAYAT---CTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQ 86
T G + + + P T C NT+ S+ C CK G+ + G C D+DECSQ
Sbjct: 2445 TDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDIS-------GTSCIDLDECSQ 2497
Query: 87 SPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHS 146
SP+PC N CKN G Y+CSC G+ V + G +C D++EC T +H+
Sbjct: 2498 SPKPC--NYICKNTEGSYQCSCPRGY--------VLQEDGK-TCKDLDECQTK----QHN 2542
Query: 147 D---CVNSMGSYSCSCQVGFISRNSTCEDVDEC-ADPRACPEHATCNNTVGNYSCFCNPG 202
CVN++G ++C C GF ++ C D +EC + P C C NT G++SC C G
Sbjct: 2543 CQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRG 2602
Query: 203 FESSSGHLSFQGLKASCEDIDECTEMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQ 262
F L GL +CED+DEC C N G Y C C G+ Q
Sbjct: 2603 FS-----LDATGL--NCEDVDECDGNHRCQHGCQNILGGYRCGCPQGYIQHY-------Q 2648
Query: 263 GVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGF 300
+C D +EC +P+ CG S C N LGSY C C +GF
Sbjct: 2649 WNQCVDENEC-SNPNACGSAS-CYNTLGSYKCACPSGF 2684
Score = 140 bits (352), Expect = 7e-33
Identities = 102/328 (31%), Positives = 137/328 (41%), Gaps = 68/328 (20%)
Query: 26 RKPNTKG----NNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDI 81
R+P+ +G N CR C N + SY C C +GF SS+ G C D
Sbjct: 2329 RRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSS-------GTECLDN 2381
Query: 82 DE----CSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDW----------------- 120
+ C SS +NL + +C C DG G W
Sbjct: 2382 RQGLCFAEVLQTICQMASSSRNLVTKSECCC-DG-----GRGWGHQCELCPLPGTAQYKK 2435
Query: 121 -VPGKPG-NFSCTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGFIS--RNSTCEDVDEC 176
P PG DI+EC + C+N+MGS+ C C+VG+ + ++C D+DEC
Sbjct: 2436 ICPHGPGYTTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDEC 2495
Query: 177 AD-PRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDEC-TEMCPINST 234
+ P+ C + C NT G+Y C C G+ Q +C+D+DEC T+
Sbjct: 2496 SQSPKPC--NYICKNTEGSYQCSCPRGYV-------LQEDGKTCKDLDECQTKQHNCQFL 2546
Query: 235 CTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSC 294
C NT G + C C PGF T C D +EC PS CG IC N GS+SC
Sbjct: 2547 CVNTLGGFTCKCPPGF---------TQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSC 2597
Query: 295 GCIAGFHPNPEG------SQKDGNFSCQ 316
C GF + G + DGN CQ
Sbjct: 2598 ECQRGFSLDATGLNCEDVDECDGNHRCQ 2625
Score = 138 bits (348), Expect = 2e-32
Identities = 95/328 (28%), Positives = 129/328 (39%), Gaps = 76/328 (23%)
Query: 33 NNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCG 92
N C+ Y C NT+ S+ C C GF + + C DIDEC SP CG
Sbjct: 1075 NECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERN-------CTDIDECRISPDLCG 1127
Query: 93 PNSSCKNLSGRYKCSCLDGFSS-------------------------------------P 115
+ C N G ++C C +G+ S P
Sbjct: 1128 -SGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCP 1186
Query: 116 TGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGFISR--NSTCEDV 173
G++ P + C DINEC S + CVN +G+Y CSC G+ + C D+
Sbjct: 1187 LGHELSPSRE---DCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDI 1243
Query: 174 DECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDEC---TEMCP 230
DEC + C N+ G+Y C C+ G+ + SC DIDEC ++C
Sbjct: 1244 DECMIMNGGCD-TQCTNSEGSYECSCSEGY-------ALMPDGRSCADIDECENNPDICD 1295
Query: 231 INSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALG 290
CTN PG Y C C+ GF S C D++EC + + C C N G
Sbjct: 1296 -GGQCTNIPGEYRCLCYDGFMASMDMKT-------CIDVNECDLNSNICMFGE-CENTKG 1346
Query: 291 SYSCGCIAGFHPNPEGSQKDGNFSCQRV 318
S+ C C G+ S K G C V
Sbjct: 1347 SFICHCQLGY------SVKKGTTGCTDV 1368
Score = 135 bits (339), Expect = 2e-31
Identities = 99/347 (28%), Positives = 136/347 (39%), Gaps = 100/347 (28%)
Query: 35 CRDSTLCPAY------ATCTNTVDSYYCACKQGFLSSNGQNHFKD----------PGVRC 78
C D C A+ TC NT+ +Y C C ++ NG ++ D G C
Sbjct: 1690 CEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTC 1749
Query: 79 KD---------------------IDECSQSPQP--------CG---------------PN 94
++ C P P CG
Sbjct: 1750 ENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDI 1809
Query: 95 SSCKNLSG------------RYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLT-SSV 141
CK + G ++C C GFS ND + C DI+EC ++
Sbjct: 1810 DECKEIPGICANGVCINQIGSFRCECPTGFSY---NDLL------LVCEDIDECSNGDNL 1860
Query: 142 CPEHSDCVNSMGSYSCSCQVGF-ISRNSTCEDVDECAD-PRACPEHATCNNTVGNYSCFC 199
C ++DC+NS GSY C C GF +S N C D +EC + P C H C + G+Y C C
Sbjct: 1861 CQRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVC-SHGLCVDLQGSYQCIC 1919
Query: 200 NPGFESSSGHLSFQGLKASCEDIDECTEMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNF 259
+ GF++S + C D+DEC N TC NT GSY C C+PGF ++
Sbjct: 1920 HNGFKASQD-------QTMCMDVDECERHPCGNGTCKNTVGSYNCLCYPGFELTHNN--- 1969
Query: 260 TDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEG 306
+C DIDEC N C N +GS+ C C G+ P+G
Sbjct: 1970 -----DCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDG 2011
Score = 135 bits (339), Expect = 2e-31
Identities = 101/323 (31%), Positives = 123/323 (38%), Gaps = 65/323 (20%)
Query: 33 NNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCG 92
N C + L A+ C NT SY C C G+ Q CKD+DEC++ C
Sbjct: 2255 NECAQNPLLCAFR-CMNTFGSYECTCPIGYALREDQK-------MCKDLDECAEGLHDCE 2306
Query: 93 PNSS-CKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNS 151
CKNL G + C C G + +P C D NEC T E+ CVN
Sbjct: 2307 SRGMMCKNLIGTFMCICPPGMAR---------RPDGEGCVDENECRTKPGICENGRCVNI 2357
Query: 152 MGSYSCSCQVGFISRNSTCEDVDECADPRA-----------CPEHATCNNTVGNYSCFCN 200
+GSY C C GF S +S E C D R C ++ N V C C+
Sbjct: 2358 IGSYRCECNEGFQSSSSGTE----CLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCD 2413
Query: 201 PGFESSSGHLSF-----------------QGLKASCEDIDECTEMCPI--NSTCTNTPGS 241
G GH G DIDEC M + N C NT GS
Sbjct: 2414 GG--RGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTNGQCINTMGS 2471
Query: 242 YFCTCHPGFAPSNGQLNFTD-QGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGF 300
+ C C G+ TD G C D+DEC Q P C N IC N GSY C C G+
Sbjct: 2472 FRCFCKVGYT--------TDISGTSCIDLDECSQSPKPC--NYICKNTEGSYQCSCPRGY 2521
Query: 301 HPNPEGSQKDGNFSCQRVLFKCK 323
+G CQ C+
Sbjct: 2522 VLQEDGKTCKDLDECQTKQHNCQ 2544
Score = 134 bits (338), Expect = 3e-31
Identities = 78/228 (34%), Positives = 106/228 (46%), Gaps = 38/228 (16%)
Query: 32 GNNCRDSTLCPAYA-----TCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQ 86
G C+D C C NT+ + C C GF Q+H C D +EC
Sbjct: 2527 GKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFT----QHH-----TACIDNNECGS 2577
Query: 87 SPQPCGPNSSCKNLSGRYKCSCLDGFS-SPTGNDWVPGKPGNFSCTDINECLTSSVCPEH 145
P CG C+N G + C C GFS TG +C D++EC + C +H
Sbjct: 2578 QPSLCGAKGICQNTPGSFSCECQRGFSLDATG----------LNCEDVDECDGNHRC-QH 2626
Query: 146 SDCVNSMGSYSCSCQVGFISRN--STCEDVDECADPRACPEHATCNNTVGNYSCFCNPGF 203
C N +G Y C C G+I + C D +EC++P AC A+C NT+G+Y C C GF
Sbjct: 2627 G-CQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGS-ASCYNTLGSYKCACPSGF 2684
Query: 204 ESSSGHLSFQGLKASCEDIDECTEMC-PINSTCTNTPGSYFCTCHPGF 250
SF ++C D++EC+ P N C+NT G Y C C PG+
Sbjct: 2685 -------SFDQFSSACHDVNECSSSKNPCNYGCSNTEGGYLCGCPPGY 2725
Score = 130 bits (328), Expect = 4e-30
Identities = 84/247 (34%), Positives = 124/247 (50%), Gaps = 37/247 (14%)
Query: 79 KDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLT 138
+DI+EC+ P C N C+NL G Y+C+C G+ P G +C DI+ECL
Sbjct: 767 RDINECALDPDICA-NGICENLRGSYRCNCNSGYE--------PDASGR-NCIDIDECLV 816
Query: 139 SSVCPEHSDCVNSMGSYSCSCQVGFISR--NSTCEDVDECADPRACPEHATCNNTVGNYS 196
+ + ++ C N+ GSYSC+C G++ R TCED++EC + C A C N +G+++
Sbjct: 817 NRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINEC-ESNPCVNGA-CRNNLGSFN 874
Query: 197 CFCNPGFE-SSSGHLSFQGLKASCEDIDECTEMCPIN-------STCTNTPGSYFCT--- 245
C C+PG + SS+G + LK +C ++ C +N S C T G+ + +
Sbjct: 875 CECSPGSKLSSTGLICIDSLKGTCW-LNIQDSRCEVNINGATLKSECCATLGAAWGSPCE 933
Query: 246 -CHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNP 304
C A G +GV C D++EC P C PN C N+ GS+ C C P
Sbjct: 934 RCELDTACPRGLARI--KGVTCEDVNECEVFPGVC-PNGRCVNSKGSFHCEC-------P 983
Query: 305 EGSQKDG 311
EG DG
Sbjct: 984 EGLTLDG 990
Score = 130 bits (326), Expect = 7e-30
Identities = 99/302 (32%), Positives = 128/302 (42%), Gaps = 57/302 (18%)
Query: 12 CCVMHSWEGHIRPTRKPNTKGNNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHF 71
C V +W KP TK TLCP A N D G+ +
Sbjct: 1027 CAVGAAWGTECEECPKPGTK----EYETLCPRGAGFANRGDVL-----------TGRPFY 1071
Query: 72 KDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCT 131
KD I+EC P C C+N G +KC C GF+ +CT
Sbjct: 1072 KD-------INECKAFPGMC-TYGKCRNTIGSFKCRCNSGFALDMEER---------NCT 1114
Query: 132 DINECLTSSVCPEHSDCVNSMGSYSCSCQVGFIS---RNSTCEDVDEC-ADPRACPEHAT 187
DI+EC S CVN+ GS+ C C G+ S C D+DEC +P C T
Sbjct: 1115 DIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLC-RGGT 1173
Query: 188 CNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECT---EMCPINSTCTNTPGSYFC 244
C NT G++ C C G E S + C DI+EC+ +C N C N G+Y C
Sbjct: 1174 CVNTEGSFQCDCPLGHELSPS-------REDCVDINECSLSDNLCR-NGKCVNMIGTYQC 1225
Query: 245 TCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNP 304
+C+PG+ Q QG C DIDEC C ++ CTN+ GSY C C G+ P
Sbjct: 1226 SCNPGY-----QATPDRQG--CTDIDECMIMNGGC--DTQCTNSEGSYECSCSEGYALMP 1276
Query: 305 EG 306
+G
Sbjct: 1277 DG 1278
Score = 128 bits (322), Expect = 2e-29
Identities = 105/364 (28%), Positives = 137/364 (37%), Gaps = 103/364 (28%)
Query: 35 CRDSTLCPAY----ATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQP 90
C D C + TC NTV SY C C GF ++ + C DIDECS
Sbjct: 1932 CMDVDECERHPCGNGTCKNTVGSYNCLCYPGFELTHNND--------CLDIDECSSFFGQ 1983
Query: 91 CGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVN 150
N C N G +KC C +G+ P +C D NEC+ C N
Sbjct: 1984 VCRNGRCFNEIGSFKCLCNEGYELT---------PDGKNCIDTNECVALPGSCSPGTCQN 2034
Query: 151 SMGSYSCSCQVGFISRNSTCEDVDEC-ADPRACPEHATCNNTVGNYSCFCNPGFESS--- 206
GS+ C C G+ ++ C D++EC DP C +C NT G + C C PGF S
Sbjct: 2035 LEGSFRCICPPGYEVKSENCIDINECDEDPNICL-FGSCTNTPGGFQCLCPPGFVLSDNG 2093
Query: 207 --------------------SGHLSFQGLKASC-------EDIDECTEMCPIN------- 232
S +F KA C E + E+CP +
Sbjct: 2094 RRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQD 2153
Query: 233 --------------------------STCTN-----TPGSYFCTCHPGFAPSNGQLNFTD 261
C+N T GS+ C C G+ L++T
Sbjct: 2154 LCPYGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGY-----NLDYT- 2207
Query: 262 QGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQKDGNFSCQRVL-- 319
GV C D DEC + CG N CTN +GS+ C C GF P P + +D N Q L
Sbjct: 2208 -GVRCVDTDEC-SIGNPCG-NGTCTNVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLC 2264
Query: 320 -FKC 322
F+C
Sbjct: 2265 AFRC 2268
Score = 128 bits (321), Expect = 3e-29
Identities = 82/230 (35%), Positives = 102/230 (44%), Gaps = 34/230 (14%)
Query: 81 IDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSS 140
ID C C N C Y+C C G+ D C D++EC TS+
Sbjct: 495 IDICKHHANLC-LNGRCIPTVSSYRCECNMGYKQDANGD----------CIDVDEC-TSN 542
Query: 141 VCPEHSDCVNSMGSYSCSCQVGF--ISRNSTCEDVDECADPRACPEHATCNNTVGNYSCF 198
C + DCVN+ GSY C C GF C D+DEC ++ C NT G++ C
Sbjct: 543 PCT-NGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCI 601
Query: 199 CNPGFESSSGHLSFQGLKASCEDIDECT--EMCPINSTCTNTPGSYFCTCHPGFAPSNGQ 256
CN GFE L+ G +C D DECT MC +N C N GS+ C C PGF
Sbjct: 602 CNAGFE-----LTTDG--KNCVDHDECTTTNMC-LNGMCINEDGSFKCICKPGFV----- 648
Query: 257 LNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEG 306
G C D+DEC Q P C N C N+ GS+ C C G +G
Sbjct: 649 --LAPNGRYCTDVDEC-QTPGIC-MNGHCINSEGSFRCDCPPGLAVGMDG 694
Score = 125 bits (313), Expect = 2e-28
Identities = 82/242 (33%), Positives = 111/242 (45%), Gaps = 40/242 (16%)
Query: 33 NNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCG 92
N C +S + C NT S+ C C G+ + GVRC D DECS PCG
Sbjct: 2173 NECLESPGICSNGQCINTDGSFRCECPMGY-------NLDYTGVRCVDTDECSIG-NPCG 2224
Query: 93 PNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNSM 152
N +C N+ G ++C+C +GF PG N C DINEC + + C+N+
Sbjct: 2225 -NGTCTNVIGSFECNCNEGFE--------PGPMMN--CEDINECAQNPLLCAFR-CMNTF 2272
Query: 153 GSYSCSCQVGFISR--NSTCEDVDECADP-RACPEHA-TCNNTVGNYSCFCNPGFESSSG 208
GSY C+C +G+ R C+D+DECA+ C C N +G + C C PG
Sbjct: 2273 GSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPG------ 2326
Query: 209 HLSFQGLKASCEDIDECTEMCPI--NSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVEC 266
++ + C D +EC I N C N GSY C C+ GF S+ G EC
Sbjct: 2327 -MARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSS-------SGTEC 2378
Query: 267 RD 268
D
Sbjct: 2379 LD 2380
Score = 122 bits (305), Expect = 2e-27
Identities = 99/351 (28%), Positives = 134/351 (38%), Gaps = 113/351 (32%)
Query: 24 PTRKPNTKGNNCRDSTLCPAYATCTNTVDSYYCACKQGF-LSSNGQNHFKDPGVRCKDID 82
PT++ + C + + C NT S+ C C GF L+++G+N C D D
Sbjct: 568 PTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDGKN--------CVDHD 619
Query: 83 ECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVC 142
EC+ + N C N G +KC C GF P CTD++EC T +C
Sbjct: 620 ECTTTNMCL--NGMCINEDGSFKCICKPGFVL---------APNGRYCTDVDECQTPGIC 668
Query: 143 PEHSDCVNSMGSYSCSCQVGF-----------ISRNSTC------------------EDV 173
+ C+NS GS+ C C G STC +
Sbjct: 669 -MNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSE 727
Query: 174 DECADP--------RACPE------HATCNNTV--------------------------- 192
CA+P + CP H C++ V
Sbjct: 728 CCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGRDINECALDPDICANGICENL 787
Query: 193 -GNYSCFCNPGFE-SSSGHLSFQGLKASCEDIDEC--TEMCPINSTCTNTPGSYFCTCHP 248
G+Y C CN G+E +SG +C DIDEC + N C NTPGSY CTC P
Sbjct: 788 RGSYRCNCNSGYEPDASGR--------NCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPP 839
Query: 249 GFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAG 299
G+ F + C DI+EC +P N C N LGS++C C G
Sbjct: 840 GYV-------FRTETETCEDINECESNPCV---NGACRNNLGSFNCECSPG 880
Score = 120 bits (300), Expect = 7e-27
Identities = 71/208 (34%), Positives = 93/208 (44%), Gaps = 31/208 (14%)
Query: 47 CTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKC 106
C TV SY C C G+ +D C D+DEC+ +P C N C N G Y C
Sbjct: 510 CIPTVSSYRCECNMGYK--------QDANGDCIDVDECTSNP--C-TNGDCVNTPGSYYC 558
Query: 107 SCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGF--I 164
C GF P +C DI+EC+ + V ++ CVN+ GS+ C C GF
Sbjct: 559 KCHAGFQRT---------PTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELT 609
Query: 165 SRNSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDE 224
+ C D DEC C + C N G++ C C PGF + C D+DE
Sbjct: 610 TDGKNCVDHDECTTTNMC-LNGMCINEDGSFKCICKPGFVLAPN-------GRYCTDVDE 661
Query: 225 C-TEMCPINSTCTNTPGSYFCTCHPGFA 251
C T +N C N+ GS+ C C PG A
Sbjct: 662 CQTPGICMNGHCINSEGSFRCDCPPGLA 689
Score = 118 bits (296), Expect = 2e-26
Identities = 98/359 (27%), Positives = 138/359 (38%), Gaps = 76/359 (21%)
Query: 47 CTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKC 106
C NT S+ C C QG+ S +D + C+DIDEC P CGP +C N G Y C
Sbjct: 1666 CINTFGSFQCECPQGYYLS------EDTRI-CEDIDECFAHPGVCGP-GTCYNTLGNYTC 1717
Query: 107 -------------SCLD--------GFSSPTGNDWVP--------------GKPGNFSCT 131
+C+D ++ T + +P GK N C
Sbjct: 1718 ICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWNKPC- 1776
Query: 132 DINECLTSSVCPEHSDCVNSMGSYSCSCQVGFISRNSTCEDVDECADPRACPEHATCNNT 191
C T + C N G F D+DEC + + C N
Sbjct: 1777 --EPCPTPGTADFKTICGNIPG-------FTFDIHTGKAVDIDECKEIPGICANGVCINQ 1827
Query: 192 VGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECT---EMCPINSTCTNTPGSYFCTCHP 248
+G++ C C GF S+ L CEDIDEC+ +C N+ C N+PGSY C C
Sbjct: 1828 IGSFRCECPTGF-------SYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCECAA 1880
Query: 249 GFAPS-NGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGS 307
GF S NG C D +EC + P+ C + +C + GSY C C GF + + +
Sbjct: 1881 GFKLSPNG---------ACVDRNECLEIPNVCS-HGLCVDLQGSYQCICHNGFKASQDQT 1930
Query: 308 QKDGNFSCQRVLFKCKEDVIPDNKQIQQCQEGTAVKPAYVSFCAQINNIFSVLDKVCEN 366
C+R C + C + + + C I+ S +VC N
Sbjct: 1931 MCMDVDECER--HPCGNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRN 1987
Score = 107 bits (266), Expect = 6e-23
Identities = 98/353 (27%), Positives = 134/353 (37%), Gaps = 106/353 (30%)
Query: 47 CTNTVDSYYCACKQGFLSS-------------------NGQNHFKDPGVRCKDIDECSQS 87
C+NTV SY+C C +G+++S NG+ + PG K +C
Sbjct: 334 CSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSGLVNGRCAQELPGRMTKM--QCCCE 391
Query: 88 PQPCG-----PNSSCKNLSGRYKCSCLDGFS----------------------SPTGNDW 120
P C P + S Y+ C+DG S GN +
Sbjct: 392 PGRCWGIGTIPEACPVRGSEEYRRLCMDGLPMGGIPGSAGSRPGGTGGNGFAPSGNGNGY 451
Query: 121 VPGKPG--------NFS-------------------CTDINECLTSSVCPEHSD------ 147
PG G FS T +N+ T +C H++
Sbjct: 452 GPGGTGFIPIPGGNGFSPGVGGAGVGAGGQGPIITGLTILNQ--TIDICKHHANLCLNGR 509
Query: 148 CVNSMGSYSCSCQVGFIS-RNSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESS 206
C+ ++ SY C C +G+ N C DVDEC C + C NT G+Y C C+ GF+ +
Sbjct: 510 CIPTVSSYRCECNMGYKQDANGDCIDVDECTS-NPCT-NGDCVNTPGSYYCKCHAGFQRT 567
Query: 207 SGHLSFQGLKASCEDIDECTE---MCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQG 263
K +C DIDEC + +C N C NT GS+ C C+ GF T G
Sbjct: 568 P-------TKQACIDIDECIQNGVLCK-NGRCVNTDGSFQCICNAGF-------ELTTDG 612
Query: 264 VECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQKDGNFSCQ 316
C D DEC + N +C N GS+ C C GF P G CQ
Sbjct: 613 KNCVDHDEC--TTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDECQ 663
Score = 106 bits (264), Expect = 1e-22
Identities = 116/447 (25%), Positives = 154/447 (34%), Gaps = 140/447 (31%)
Query: 27 KPNTKGNNCRDSTLCPAY------ATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKD 80
+P+ G NC D C C NT SY C C G++ F+ C+D
Sbjct: 800 EPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYV-------FRTETETCED 852
Query: 81 IDECSQSPQPCGPNSSCKNLSGRYKCSCLDG----------FSSPTGNDWVP-------- 122
I+EC + PC N +C+N G + C C G S G W+
Sbjct: 853 INECESN--PC-VNGACRNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEV 909
Query: 123 -------------------GKP-----------------GNFSCTDINEC-LTSSVCPEH 145
G P +C D+NEC + VCP +
Sbjct: 910 NINGATLKSECCATLGAAWGSPCERCELDTACPRGLARIKGVTCEDVNECEVFPGVCP-N 968
Query: 146 SDCVNSMGSYSCSCQVGFI--SRNSTCEDV-----------DECADP------------- 179
CVNS GS+ C C G C D+ DEC P
Sbjct: 969 GRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCA 1028
Query: 180 ---------RACPEHATCNNTVGNYSCFC--NPGFESSSGHLSFQGLKASCEDIDECTE- 227
CP+ T Y C GF + L+ + +DI+EC
Sbjct: 1029 VGAAWGTECEECPKPGT-----KEYETLCPRGAGFANRGDVLTG---RPFYKDINECKAF 1080
Query: 228 --MCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSIC 285
MC C NT GS+ C C+ GFA + N C DIDECR P CG + IC
Sbjct: 1081 PGMCTYGK-CRNTIGSFKCRCNSGFALDMEERN-------CTDIDECRISPDLCG-SGIC 1131
Query: 286 TNALGSYSCGCIAGFHPNPEGSQKDGNF----SCQRVLFKCKEDVIPDNKQIQQCQ--EG 339
N GS+ C C G+ G N C+R C+ + + QC G
Sbjct: 1132 VNTPGSFECECFEGYE---SGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLG 1188
Query: 340 TAVKPAYVSFCAQINNIFSVLDKVCEN 366
+ P+ C IN S+ D +C N
Sbjct: 1189 HELSPSRED-CVDINEC-SLSDNLCRN 1213
Score = 88.2 bits (217), Expect = 3e-17
Identities = 84/289 (29%), Positives = 115/289 (39%), Gaps = 63/289 (21%)
Query: 26 RKPNTKGNNCRDSTLCPAYAT-----------CTNTVDSYYCA------CKQGFLSSN-G 67
R PN G+ S CP + T C N+ +C+ C G +SS G
Sbjct: 84 RGPNVCGSRFH-SYCCPGWKTLPGGNQCIVPICRNSCGDGFCSRPNMCTCSSGQISSTCG 142
Query: 68 QNHFKDPGVRCKDIDECSQSPQPCGPN------------SSCKN---LSGRYKCSCLDGF 112
+ VRC + C+ C + C+N G +C+C+ GF
Sbjct: 143 SKSIQQCSVRCMNGGTCADDHCQCQKGYIGTYCGQPVCENGCQNGGRCIGPNRCACVYGF 202
Query: 113 SSPT-GNDWVPGKPGNFSCTDINEC---LTSSVCPEHSDC--VNSMGSYSCS-------- 158
+ P D+ G F+ + C LT VC + C + + C
Sbjct: 203 TGPQCERDYRTGPC--FTQVNNQMCQGQLTGIVCTKTLCCATIGRAWGHPCEMCPAQPQP 260
Query: 159 CQVGFIS--RNSTCEDVDEC-ADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGL 215
C+ GFI R C+DVDEC A P C + C NTVG++ C C G + S
Sbjct: 261 CRRGFIPNIRTGACQDVDECQAIPGIC-QGGNCINTVGSFECRCPAGHKQSE-------T 312
Query: 216 KASCEDIDECTEMCPINST--CTNTPGSYFCTCHPGFAPSNGQLNFTDQ 262
CEDIDEC+ + I T C+NT GSYFC C G+ S DQ
Sbjct: 313 TQKCEDIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCIDQ 361
Score = 72.8 bits (177), Expect = 1e-12
Identities = 56/210 (26%), Positives = 86/210 (40%), Gaps = 28/210 (13%)
Query: 56 CACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQP---CGPNSSCKNLSGR---YKCSCL 109
CAC GF + ++ + ++ Q C C + GR + C
Sbjct: 196 CACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATI-GRAWGHPCEMC 254
Query: 110 DGFSSPTGNDWVPG-KPGNFSCTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGFISRNS 168
P ++P + G +C D++EC + +C+N++GS+ C C G +
Sbjct: 255 PAQPQPCRRGFIPNIRTG--ACQDVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSET 312
Query: 169 T--CEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECT 226
T CED+DEC+ E C+NTVG+Y C C G+ +S+ ID+ T
Sbjct: 313 TQKCEDIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTD---------GSRCIDQRT 363
Query: 227 EMC---PINSTCT-NTPG---SYFCTCHPG 249
MC +N C PG C C PG
Sbjct: 364 GMCFSGLVNGRCAQELPGRMTKMQCCCEPG 393
>gi|46249414 latent transforming growth factor beta binding protein 1
isoform LTBP-1L [Homo sapiens]
Length = 1722
Score = 170 bits (430), Expect = 6e-42
Identities = 100/279 (35%), Positives = 133/279 (47%), Gaps = 44/279 (15%)
Query: 33 NNCRDSTLCPAYATCTNTVDSYYCA-CKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPC 91
+ C + + CP C N+ SY C C +GF NGQ C D+DEC + P C
Sbjct: 1001 DECLNPSTCPD-EQCVNSPGSYQCVPCTEGFRGWNGQ---------CLDVDECLE-PNVC 1049
Query: 92 GPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNS 151
N C NL G Y CSC G++ P + C DI+EC ++C + C N+
Sbjct: 1050 A-NGDCSNLEGSYMCSCHKGYTRT---------PDHKHCRDIDECQQGNLCV-NGQCKNT 1098
Query: 152 MGSYSCSCQVGF--ISRNSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGH 209
GS+ C+C G+ + CED+DEC C H C NT G++ C C+ G+ +S
Sbjct: 1099 EGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCA-HGQCRNTEGSFQCVCDQGYRAS--- 1154
Query: 210 LSFQGLKASCEDIDECTEMCPI--NSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECR 267
GL CEDI+EC E + C NT GSY CTC GF D C+
Sbjct: 1155 ----GLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQ--------LDDNKTCQ 1202
Query: 268 DIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEG 306
DI+EC + P CGP C N GS+ C C GF + +G
Sbjct: 1203 DINEC-EHPGLCGPQGECLNTEGSFHCVCQQGFSISADG 1240
Score = 165 bits (418), Expect = 2e-40
Identities = 100/341 (29%), Positives = 150/341 (43%), Gaps = 52/341 (15%)
Query: 33 NNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCG 92
+ C + +C A C+N SY C+C +G+ + H C+DIDEC Q C
Sbjct: 1041 DECLEPNVC-ANGDCSNLEGSYMCSCHKGYTRTPDHKH-------CRDIDECQQG-NLC- 1090
Query: 93 PNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNSM 152
N CKN G ++C+C G+ D C DI+EC +C H C N+
Sbjct: 1091 VNGQCKNTEGSFRCTCGQGYQLSAAKD---------QCEDIDECQHRHLCA-HGQCRNTE 1140
Query: 153 GSYSCSCQVGFISRN--STCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHL 210
GS+ C C G+ + CED++EC + ++ + C NT G+Y C C GF+
Sbjct: 1141 GSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNK- 1199
Query: 211 SFQGLKASCEDIDECTE--MCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRD 268
+C+DI+EC +C C NT GS+ C C GF+ S G C D
Sbjct: 1200 -------TCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISA-------DGRTCED 1245
Query: 269 IDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQKDGNFSCQRVLFKCKEDVIP 328
IDEC + + C + C N GS+ C C GF +G C+ + C E
Sbjct: 1246 IDECVNN-TVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAF-- 1302
Query: 329 DNKQIQQCQEGTAVKPAYVSFCAQINNIFSVLDKVCENKTT 369
C+ V+ +++ CA N +S + C ++T+
Sbjct: 1303 -------CEN---VEGSFLCVCADENQEYSPMTGQCRSRTS 1333
Score = 162 bits (409), Expect = 2e-39
Identities = 107/309 (34%), Positives = 135/309 (43%), Gaps = 73/309 (23%)
Query: 47 CTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKC 106
C NT S+ C C GF++S + G C D+DEC + P CG C N G ++C
Sbjct: 932 CENTEGSFLCICPAGFMAS-------EEGTNCIDVDECLR-PDVCG-EGHCVNTVGAFRC 982
Query: 107 SCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNSMGSYSC-SCQVGFIS 165
D T C DI+ECL S CP+ CVNS GSY C C GF
Sbjct: 983 EYCDSGYRMTQRG---------RCEDIDECLNPSTCPD-EQCVNSPGSYQCVPCTEGFRG 1032
Query: 166 RNSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDEC 225
N C DVDEC +P C + C+N G+Y C C+ G+ + H C DIDEC
Sbjct: 1033 WNGQCLDVDECLEPNVC-ANGDCSNLEGSYMCSCHKGYTRTPDH-------KHCRDIDEC 1084
Query: 226 TE--MCPINSTCTNTPGSYFCTCHPGFAPS-------------------NGQLNFT---- 260
+ +C +N C NT GS+ CTC G+ S +GQ T
Sbjct: 1085 QQGNLC-VNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSF 1143
Query: 261 ----DQGV-------ECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQK 309
DQG C DI+EC +D S C C N GSY C C P+G Q
Sbjct: 1144 QCVCDQGYRASGLGDHCEDINECLEDKSVC-QRGDCINTAGSYDCTC-------PDGFQL 1195
Query: 310 DGNFSCQRV 318
D N +CQ +
Sbjct: 1196 DDNKTCQDI 1204
Score = 154 bits (389), Expect = 3e-37
Identities = 104/302 (34%), Positives = 143/302 (47%), Gaps = 49/302 (16%)
Query: 22 IRPTRKPNTKGNNCR-DSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKD 80
I PT+ T+ N C + +C A C N Y C C +G+ S Q +C D
Sbjct: 867 IAPTQV--TEINECTVNPDICGA-GHCINLPVRYTCICYEGYRFSEQQR-------KCVD 916
Query: 81 IDECSQSPQPCGPNSSCKNLSGRYKCSCLDGF-SSPTGNDWVPGKPGNFSCTDINECLTS 139
IDEC+Q C C+N G + C C GF +S G +C D++ECL
Sbjct: 917 IDECTQVQHLCS-QGRCENTEGSFLCICPAGFMASEEGT----------NCIDVDECLRP 965
Query: 140 SVCPEHSDCVNSMGSYSCS-CQVGF-ISRNSTCEDVDECADPRACPEHATCNNTVGNYSC 197
VC E CVN++G++ C C G+ +++ CED+DEC +P CP+ C N+ G+Y C
Sbjct: 966 DVCGE-GHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDE-QCVNSPGSYQC 1023
Query: 198 F-CNPGFESSSGHLSFQGLKASCEDIDECTE--MCPINSTCTNTPGSYFCTCHPGFAPSN 254
C G F+G C D+DEC E +C N C+N GSY C+CH G+
Sbjct: 1024 VPCTEG---------FRGWNGQCLDVDECLEPNVC-ANGDCSNLEGSYMCSCHKGYTR-- 1071
Query: 255 GQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQKDGNFS 314
T CRDIDEC+Q + C N C N GS+ C C G+ + Q +
Sbjct: 1072 -----TPDHKHCRDIDECQQG-NLC-VNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDE 1124
Query: 315 CQ 316
CQ
Sbjct: 1125 CQ 1126
Score = 152 bits (385), Expect = 1e-36
Identities = 91/282 (32%), Positives = 133/282 (47%), Gaps = 41/282 (14%)
Query: 33 NNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCG 92
+ C+ LC A+ C NT S+ C C QG+ +S +H C+DI+EC + C
Sbjct: 1123 DECQHRHLC-AHGQCRNTEGSFQCVCDQGYRASGLGDH-------CEDINECLEDKSVC- 1173
Query: 93 PNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNSM 152
C N +G Y C+C DGF N +C DINEC +C +C+N+
Sbjct: 1174 QRGDCINTAGSYDCTCPDGFQLDD----------NKTCQDINECEHPGLCGPQGECLNTE 1223
Query: 153 GSYSCSCQVGF-ISRNS-TCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHL 210
GS+ C CQ GF IS + TCED+DEC + C H C+NT G++ C C GF++
Sbjct: 1224 GSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQ--- 1280
Query: 211 SFQGLKASCEDIDECTEMCPI--NSTCTNTPGSYFCTC---HPGFAPSNGQLNFTDQGVE 265
QG C D++EC + + + C N GS+ C C + ++P GQ
Sbjct: 1281 DGQG----CVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDL 1336
Query: 266 CRDIDECRQDPSTCGPN----SICTNALG----SYSCGCIAG 299
D+D+ +++ C N S+C N L C C +G
Sbjct: 1337 DVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSG 1378
Score = 133 bits (335), Expect = 6e-31
Identities = 85/244 (34%), Positives = 112/244 (45%), Gaps = 37/244 (15%)
Query: 80 DIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTS 139
+I+EC+ +P CG C NL RY C C +G+ C DI+EC
Sbjct: 874 EINECTVNPDICGAGH-CINLPVRYTCICYEGYRFSEQQR---------KCVDIDECTQV 923
Query: 140 SVCPEHSDCVNSMGSYSCSCQVGFIS--RNSTCEDVDECADPRACPEHATCNNTVGNYSC 197
C N+ GS+ C C GF++ + C DVDEC P C E C NTVG + C
Sbjct: 924 QHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGE-GHCVNTVGAFRC 982
Query: 198 -FCNPGFESSSGHLSFQGLKASCEDIDEC--TEMCPINSTCTNTPGSYFCT-CHPGFAPS 253
+C+ G+ + + CEDIDEC CP + C N+PGSY C C GF
Sbjct: 983 EYCDSGYRMTQ--------RGRCEDIDECLNPSTCP-DEQCVNSPGSYQCVPCTEGFRGW 1033
Query: 254 NGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQKDGNF 313
NGQ C D+DEC +P+ C N C+N GSY C C G+ P+
Sbjct: 1034 NGQ---------CLDVDEC-LEPNVCA-NGDCSNLEGSYMCSCHKGYTRTPDHKHCRDID 1082
Query: 314 SCQR 317
CQ+
Sbjct: 1083 ECQQ 1086
Score = 110 bits (276), Expect = 4e-24
Identities = 93/330 (28%), Positives = 122/330 (36%), Gaps = 66/330 (20%)
Query: 33 NNC-RDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPC 91
N C D ++C C NT SY C C GF + + C+DI+EC + P C
Sbjct: 1164 NECLEDKSVCQR-GDCINTAGSYDCTCPDGFQLDDNKT--------CQDINEC-EHPGLC 1213
Query: 92 GPNSSCKNLSGRYKCSCLDGFS-SPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVN 150
GP C N G + C C GFS S G +C DI+EC+ ++VC H C N
Sbjct: 1214 GPQGECLNTEGSFHCVCQQGFSISADGR----------TCEDIDECVNNTVCDSHGFCDN 1263
Query: 151 SMGSYSCSCQVGFISRNST--CEDVDECADPRACPEHATCNNTVGNYSCFC---NPGFES 205
+ GS+ C C GF + C DV+EC A C N G++ C C N +
Sbjct: 1264 TAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSP 1323
Query: 206 SSGHLSFQGLKASCEDIDECTEM---CPIN----STCTN------TPGSYFCTCHPGFA- 251
+G + D+D+ E C N S C N T CT G+
Sbjct: 1324 MTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGD 1383
Query: 252 -------PSNGQLNFTDQ------------------GVECRDIDECRQDPSTCGPNSICT 286
P G FT+ G +D DEC N C
Sbjct: 1384 NCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCL 1443
Query: 287 NALGSYSCGCIAGFHPNPEGSQKDGNFSCQ 316
N Y C C G + +P Q CQ
Sbjct: 1444 NTRPGYECYCKQGTYYDPVKLQCFDMDECQ 1473
Score = 62.4 bits (150), Expect = 2e-09
Identities = 79/302 (26%), Positives = 109/302 (36%), Gaps = 62/302 (20%)
Query: 32 GNNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPC 91
G+NC + CP T T C +GF+ + G++ + G KD DEC Q
Sbjct: 1382 GDNC-EIFPCPVLGTAEFTE---MCPKGKGFVPA-GESSSEAGGENYKDADECLLFGQEI 1436
Query: 92 GPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNS 151
N C N Y+C C G T D P C D++EC S C + CVN+
Sbjct: 1437 CKNGFCLNTRPGYECYCKQG----TYYD-----PVKLQCFDMDECQDPSSCID-GQCVNT 1486
Query: 152 MGSYSCSCQVGFI------------SRNSTCEDVDECADPRACPEHAT----CNN-TVGN 194
GSY+C C + N E+ D D C EH + C+ VG
Sbjct: 1487 EGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQD--LCWEHLSDEYVCSRPLVGK 1544
Query: 195 YS----CFCNPGFESSSGHLSFQGLKASCEDIDECTEMCPINSTCTNTP----------G 240
+ C C G E+ + LK D D+ ++C I T P
Sbjct: 1545 QTTYTECCCLYG-EAWGMQCALCPLK----DSDDYAQLCNIPVTGRRQPYGRDALVDFSE 1599
Query: 241 SYFCTCHPGFAPSNGQLNFTD-QGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAG 299
Y P F +F + Q EC ++ C N C Y+C C G
Sbjct: 1600 QYTPEADPYFIQDRFLNSFEELQAEECGILNGCE--------NGRCVRVQEGYTCDCFDG 1651
Query: 300 FH 301
+H
Sbjct: 1652 YH 1653
Score = 60.1 bits (144), Expect = 9e-09
Identities = 62/242 (25%), Positives = 90/242 (37%), Gaps = 30/242 (12%)
Query: 33 NNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCG 92
+ C+D + C C NT SY C C + + P + I+E C
Sbjct: 1470 DECQDPSSC-IDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCW 1528
Query: 93 PNSSCKNLSGR---------YKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCP 143
+ S + + R +C CL G + P K + N +T P
Sbjct: 1529 EHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQP 1588
Query: 144 EHSDC-VNSMGSYSCSCQVGFISR---NSTCE-DVDECADPRACPEHATCNNTVGNYSCF 198
D V+ Y+ FI NS E +EC C E+ C Y+C
Sbjct: 1589 YGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGC-ENGRCVRVQEGYTCD 1647
Query: 199 CNPGFESSSGHLSFQGLKASCEDIDECTEM------CPINSTCTNTPGSYFCTCHPGFAP 252
C G+ + K +C D++EC E+ C N+ C NT GSY C C PG+ P
Sbjct: 1648 CFDGYHLDTA-------KMTCVDVNECDELNNRMSLCK-NAKCINTDGSYKCLCLPGYVP 1699
Query: 253 SN 254
S+
Sbjct: 1700 SD 1701
Score = 58.9 bits (141), Expect = 2e-08
Identities = 74/301 (24%), Positives = 106/301 (35%), Gaps = 49/301 (16%)
Query: 32 GNNCRDSTLCPAYAT-------CTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDEC 84
G N +D+ C + C NT Y C CKQG ++ ++C D+DEC
Sbjct: 1420 GENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQG-------TYYDPVKLQCFDMDEC 1472
Query: 85 SQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPE 144
Q P C + C N G Y C C +P + + +C E
Sbjct: 1473 -QDPSSC-IDGQCVNTEGSYNCFCTHPMVLDASEKRCI-RPAESNEQIEETDVYQDLCWE 1529
Query: 145 H-SD-------CVNSMGSYS-CSCQVG--FISRNSTCEDVDECADPRACPEHATCNNTV- 192
H SD V +Y+ C C G + + + C D + C T
Sbjct: 1530 HLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPY 1589
Query: 193 ---------GNYSCFCNPGFESSSGHLSFQGLKAS-CEDIDECTEMCPINSTCTNTPGSY 242
Y+ +P F SF+ L+A C ++ C N C Y
Sbjct: 1590 GRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCE-----NGRCVRVQEGY 1644
Query: 243 FCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHP 302
C C G+ ++ D EC DE S C N+ C N GSY C C+ G+ P
Sbjct: 1645 TCDCFDGYHLDTAKMTCVDVN-EC---DELNNRMSLC-KNAKCINTDGSYKCLCLPGYVP 1699
Query: 303 N 303
+
Sbjct: 1700 S 1700
Score = 51.6 bits (122), Expect = 3e-06
Identities = 22/45 (48%), Positives = 31/45 (68%), Gaps = 3/45 (6%)
Query: 121 VPG--KPGNFSCTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGF 163
+PG + N C DINEC VCP + +C+N+MGSY C+C++GF
Sbjct: 613 LPGYKRVNNTFCQDINECQLQGVCP-NGECLNTMGSYRCTCKIGF 656
Score = 43.9 bits (102), Expect = 7e-04
Identities = 24/59 (40%), Positives = 29/59 (49%), Gaps = 10/59 (16%)
Query: 246 CHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNP 304
C PG+ N C+DI+EC Q C PN C N +GSY C C GF P+P
Sbjct: 612 CLPGYKRVNNTF--------CQDINEC-QLQGVC-PNGECLNTMGSYRCTCKIGFGPDP 660
Score = 42.7 bits (99), Expect = 0.001
Identities = 20/36 (55%), Positives = 23/36 (63%), Gaps = 3/36 (8%)
Query: 219 CEDIDECT--EMCPINSTCTNTPGSYFCTCHPGFAP 252
C+DI+EC +CP N C NT GSY CTC GF P
Sbjct: 624 CQDINECQLQGVCP-NGECLNTMGSYRCTCKIGFGP 658
Score = 41.2 bits (95), Expect = 0.004
Identities = 21/49 (42%), Positives = 26/49 (53%), Gaps = 3/49 (6%)
Query: 78 CKDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFS-SPTGNDWVPGKP 125
C+DI+EC Q PN C N G Y+C+C GF PT + VP P
Sbjct: 624 CQDINECQL--QGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPP 670
Score = 40.8 bits (94), Expect = 0.006
Identities = 19/46 (41%), Positives = 27/46 (58%), Gaps = 2/46 (4%)
Query: 159 CQVGFISRNST-CEDVDECADPRACPEHATCNNTVGNYSCFCNPGF 203
C G+ N+T C+D++EC CP + C NT+G+Y C C GF
Sbjct: 612 CLPGYKRVNNTFCQDINECQLQGVCP-NGECLNTMGSYRCTCKIGF 656
Score = 32.3 bits (72), Expect = 2.0
Identities = 14/30 (46%), Positives = 17/30 (56%), Gaps = 1/30 (3%)
Query: 33 NNCRDSTLCPAYATCTNTVDSYYCACKQGF 62
N C+ +CP C NT+ SY C CK GF
Sbjct: 628 NECQLQGVCPN-GECLNTMGSYRCTCKIGF 656
>gi|46249412 latent transforming growth factor beta binding protein
1 isoform LTBP-1S [Homo sapiens]
Length = 1396
Score = 170 bits (430), Expect = 6e-42
Identities = 100/279 (35%), Positives = 133/279 (47%), Gaps = 44/279 (15%)
Query: 33 NNCRDSTLCPAYATCTNTVDSYYCA-CKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPC 91
+ C + + CP C N+ SY C C +GF NGQ C D+DEC + P C
Sbjct: 675 DECLNPSTCPD-EQCVNSPGSYQCVPCTEGFRGWNGQ---------CLDVDECLE-PNVC 723
Query: 92 GPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNS 151
N C NL G Y CSC G++ P + C DI+EC ++C + C N+
Sbjct: 724 A-NGDCSNLEGSYMCSCHKGYTRT---------PDHKHCRDIDECQQGNLCV-NGQCKNT 772
Query: 152 MGSYSCSCQVGF--ISRNSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGH 209
GS+ C+C G+ + CED+DEC C H C NT G++ C C+ G+ +S
Sbjct: 773 EGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCA-HGQCRNTEGSFQCVCDQGYRAS--- 828
Query: 210 LSFQGLKASCEDIDECTEMCPI--NSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECR 267
GL CEDI+EC E + C NT GSY CTC GF D C+
Sbjct: 829 ----GLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQ--------LDDNKTCQ 876
Query: 268 DIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEG 306
DI+EC + P CGP C N GS+ C C GF + +G
Sbjct: 877 DINEC-EHPGLCGPQGECLNTEGSFHCVCQQGFSISADG 914
Score = 165 bits (418), Expect = 2e-40
Identities = 100/341 (29%), Positives = 150/341 (43%), Gaps = 52/341 (15%)
Query: 33 NNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCG 92
+ C + +C A C+N SY C+C +G+ + H C+DIDEC Q C
Sbjct: 715 DECLEPNVC-ANGDCSNLEGSYMCSCHKGYTRTPDHKH-------CRDIDECQQG-NLC- 764
Query: 93 PNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNSM 152
N CKN G ++C+C G+ D C DI+EC +C H C N+
Sbjct: 765 VNGQCKNTEGSFRCTCGQGYQLSAAKD---------QCEDIDECQHRHLCA-HGQCRNTE 814
Query: 153 GSYSCSCQVGFISRN--STCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHL 210
GS+ C C G+ + CED++EC + ++ + C NT G+Y C C GF+
Sbjct: 815 GSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNK- 873
Query: 211 SFQGLKASCEDIDECTE--MCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRD 268
+C+DI+EC +C C NT GS+ C C GF+ S G C D
Sbjct: 874 -------TCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISA-------DGRTCED 919
Query: 269 IDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQKDGNFSCQRVLFKCKEDVIP 328
IDEC + + C + C N GS+ C C GF +G C+ + C E
Sbjct: 920 IDECVNN-TVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAF-- 976
Query: 329 DNKQIQQCQEGTAVKPAYVSFCAQINNIFSVLDKVCENKTT 369
C+ V+ +++ CA N +S + C ++T+
Sbjct: 977 -------CEN---VEGSFLCVCADENQEYSPMTGQCRSRTS 1007
Score = 162 bits (409), Expect = 2e-39
Identities = 107/309 (34%), Positives = 135/309 (43%), Gaps = 73/309 (23%)
Query: 47 CTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKC 106
C NT S+ C C GF++S + G C D+DEC + P CG C N G ++C
Sbjct: 606 CENTEGSFLCICPAGFMAS-------EEGTNCIDVDECLR-PDVCG-EGHCVNTVGAFRC 656
Query: 107 SCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNSMGSYSC-SCQVGFIS 165
D T C DI+ECL S CP+ CVNS GSY C C GF
Sbjct: 657 EYCDSGYRMTQRG---------RCEDIDECLNPSTCPD-EQCVNSPGSYQCVPCTEGFRG 706
Query: 166 RNSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDEC 225
N C DVDEC +P C + C+N G+Y C C+ G+ + H C DIDEC
Sbjct: 707 WNGQCLDVDECLEPNVC-ANGDCSNLEGSYMCSCHKGYTRTPDH-------KHCRDIDEC 758
Query: 226 TE--MCPINSTCTNTPGSYFCTCHPGFAPS-------------------NGQLNFT---- 260
+ +C +N C NT GS+ CTC G+ S +GQ T
Sbjct: 759 QQGNLC-VNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSF 817
Query: 261 ----DQGV-------ECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQK 309
DQG C DI+EC +D S C C N GSY C C P+G Q
Sbjct: 818 QCVCDQGYRASGLGDHCEDINECLEDKSVC-QRGDCINTAGSYDCTC-------PDGFQL 869
Query: 310 DGNFSCQRV 318
D N +CQ +
Sbjct: 870 DDNKTCQDI 878
Score = 154 bits (389), Expect = 3e-37
Identities = 104/302 (34%), Positives = 143/302 (47%), Gaps = 49/302 (16%)
Query: 22 IRPTRKPNTKGNNCR-DSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKD 80
I PT+ T+ N C + +C A C N Y C C +G+ S Q +C D
Sbjct: 541 IAPTQV--TEINECTVNPDICGA-GHCINLPVRYTCICYEGYRFSEQQR-------KCVD 590
Query: 81 IDECSQSPQPCGPNSSCKNLSGRYKCSCLDGF-SSPTGNDWVPGKPGNFSCTDINECLTS 139
IDEC+Q C C+N G + C C GF +S G +C D++ECL
Sbjct: 591 IDECTQVQHLCS-QGRCENTEGSFLCICPAGFMASEEGT----------NCIDVDECLRP 639
Query: 140 SVCPEHSDCVNSMGSYSCS-CQVGF-ISRNSTCEDVDECADPRACPEHATCNNTVGNYSC 197
VC E CVN++G++ C C G+ +++ CED+DEC +P CP+ C N+ G+Y C
Sbjct: 640 DVCGE-GHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDE-QCVNSPGSYQC 697
Query: 198 F-CNPGFESSSGHLSFQGLKASCEDIDECTE--MCPINSTCTNTPGSYFCTCHPGFAPSN 254
C G F+G C D+DEC E +C N C+N GSY C+CH G+
Sbjct: 698 VPCTEG---------FRGWNGQCLDVDECLEPNVC-ANGDCSNLEGSYMCSCHKGYTR-- 745
Query: 255 GQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQKDGNFS 314
T CRDIDEC+Q + C N C N GS+ C C G+ + Q +
Sbjct: 746 -----TPDHKHCRDIDECQQG-NLC-VNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDE 798
Query: 315 CQ 316
CQ
Sbjct: 799 CQ 800
Score = 152 bits (385), Expect = 1e-36
Identities = 91/282 (32%), Positives = 133/282 (47%), Gaps = 41/282 (14%)
Query: 33 NNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCG 92
+ C+ LC A+ C NT S+ C C QG+ +S +H C+DI+EC + C
Sbjct: 797 DECQHRHLC-AHGQCRNTEGSFQCVCDQGYRASGLGDH-------CEDINECLEDKSVC- 847
Query: 93 PNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNSM 152
C N +G Y C+C DGF N +C DINEC +C +C+N+
Sbjct: 848 QRGDCINTAGSYDCTCPDGFQLDD----------NKTCQDINECEHPGLCGPQGECLNTE 897
Query: 153 GSYSCSCQVGF-ISRNS-TCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHL 210
GS+ C CQ GF IS + TCED+DEC + C H C+NT G++ C C GF++
Sbjct: 898 GSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQ--- 954
Query: 211 SFQGLKASCEDIDECTEMCPI--NSTCTNTPGSYFCTC---HPGFAPSNGQLNFTDQGVE 265
QG C D++EC + + + C N GS+ C C + ++P GQ
Sbjct: 955 DGQG----CVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDL 1010
Query: 266 CRDIDECRQDPSTCGPN----SICTNALG----SYSCGCIAG 299
D+D+ +++ C N S+C N L C C +G
Sbjct: 1011 DVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSG 1052
Score = 133 bits (335), Expect = 6e-31
Identities = 85/244 (34%), Positives = 112/244 (45%), Gaps = 37/244 (15%)
Query: 80 DIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTS 139
+I+EC+ +P CG C NL RY C C +G+ C DI+EC
Sbjct: 548 EINECTVNPDICGAGH-CINLPVRYTCICYEGYRFSEQQR---------KCVDIDECTQV 597
Query: 140 SVCPEHSDCVNSMGSYSCSCQVGFIS--RNSTCEDVDECADPRACPEHATCNNTVGNYSC 197
C N+ GS+ C C GF++ + C DVDEC P C E C NTVG + C
Sbjct: 598 QHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGE-GHCVNTVGAFRC 656
Query: 198 -FCNPGFESSSGHLSFQGLKASCEDIDEC--TEMCPINSTCTNTPGSYFCT-CHPGFAPS 253
+C+ G+ + + CEDIDEC CP + C N+PGSY C C GF
Sbjct: 657 EYCDSGYRMTQ--------RGRCEDIDECLNPSTCP-DEQCVNSPGSYQCVPCTEGFRGW 707
Query: 254 NGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQKDGNF 313
NGQ C D+DEC +P+ C N C+N GSY C C G+ P+
Sbjct: 708 NGQ---------CLDVDEC-LEPNVCA-NGDCSNLEGSYMCSCHKGYTRTPDHKHCRDID 756
Query: 314 SCQR 317
CQ+
Sbjct: 757 ECQQ 760
Score = 110 bits (276), Expect = 4e-24
Identities = 93/330 (28%), Positives = 122/330 (36%), Gaps = 66/330 (20%)
Query: 33 NNC-RDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPC 91
N C D ++C C NT SY C C GF + + C+DI+EC + P C
Sbjct: 838 NECLEDKSVCQR-GDCINTAGSYDCTCPDGFQLDDNKT--------CQDINEC-EHPGLC 887
Query: 92 GPNSSCKNLSGRYKCSCLDGFS-SPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVN 150
GP C N G + C C GFS S G +C DI+EC+ ++VC H C N
Sbjct: 888 GPQGECLNTEGSFHCVCQQGFSISADGR----------TCEDIDECVNNTVCDSHGFCDN 937
Query: 151 SMGSYSCSCQVGFISRNST--CEDVDECADPRACPEHATCNNTVGNYSCFC---NPGFES 205
+ GS+ C C GF + C DV+EC A C N G++ C C N +
Sbjct: 938 TAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSP 997
Query: 206 SSGHLSFQGLKASCEDIDECTEM---CPIN----STCTN------TPGSYFCTCHPGFA- 251
+G + D+D+ E C N S C N T CT G+
Sbjct: 998 MTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGD 1057
Query: 252 -------PSNGQLNFTDQ------------------GVECRDIDECRQDPSTCGPNSICT 286
P G FT+ G +D DEC N C
Sbjct: 1058 NCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCL 1117
Query: 287 NALGSYSCGCIAGFHPNPEGSQKDGNFSCQ 316
N Y C C G + +P Q CQ
Sbjct: 1118 NTRPGYECYCKQGTYYDPVKLQCFDMDECQ 1147
Score = 62.4 bits (150), Expect = 2e-09
Identities = 79/302 (26%), Positives = 109/302 (36%), Gaps = 62/302 (20%)
Query: 32 GNNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPC 91
G+NC + CP T T C +GF+ + G++ + G KD DEC Q
Sbjct: 1056 GDNC-EIFPCPVLGTAEFTE---MCPKGKGFVPA-GESSSEAGGENYKDADECLLFGQEI 1110
Query: 92 GPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNS 151
N C N Y+C C G T D P C D++EC S C + CVN+
Sbjct: 1111 CKNGFCLNTRPGYECYCKQG----TYYD-----PVKLQCFDMDECQDPSSCID-GQCVNT 1160
Query: 152 MGSYSCSCQVGFI------------SRNSTCEDVDECADPRACPEHAT----CNN-TVGN 194
GSY+C C + N E+ D D C EH + C+ VG
Sbjct: 1161 EGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQD--LCWEHLSDEYVCSRPLVGK 1218
Query: 195 YS----CFCNPGFESSSGHLSFQGLKASCEDIDECTEMCPINSTCTNTP----------G 240
+ C C G E+ + LK D D+ ++C I T P
Sbjct: 1219 QTTYTECCCLYG-EAWGMQCALCPLK----DSDDYAQLCNIPVTGRRQPYGRDALVDFSE 1273
Query: 241 SYFCTCHPGFAPSNGQLNFTD-QGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAG 299
Y P F +F + Q EC ++ C N C Y+C C G
Sbjct: 1274 QYTPEADPYFIQDRFLNSFEELQAEECGILNGCE--------NGRCVRVQEGYTCDCFDG 1325
Query: 300 FH 301
+H
Sbjct: 1326 YH 1327
Score = 60.1 bits (144), Expect = 9e-09
Identities = 62/242 (25%), Positives = 90/242 (37%), Gaps = 30/242 (12%)
Query: 33 NNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCG 92
+ C+D + C C NT SY C C + + P + I+E C
Sbjct: 1144 DECQDPSSC-IDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCW 1202
Query: 93 PNSSCKNLSGR---------YKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCP 143
+ S + + R +C CL G + P K + N +T P
Sbjct: 1203 EHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQP 1262
Query: 144 EHSDC-VNSMGSYSCSCQVGFISR---NSTCE-DVDECADPRACPEHATCNNTVGNYSCF 198
D V+ Y+ FI NS E +EC C E+ C Y+C
Sbjct: 1263 YGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGC-ENGRCVRVQEGYTCD 1321
Query: 199 CNPGFESSSGHLSFQGLKASCEDIDECTEM------CPINSTCTNTPGSYFCTCHPGFAP 252
C G+ + K +C D++EC E+ C N+ C NT GSY C C PG+ P
Sbjct: 1322 CFDGYHLDTA-------KMTCVDVNECDELNNRMSLCK-NAKCINTDGSYKCLCLPGYVP 1373
Query: 253 SN 254
S+
Sbjct: 1374 SD 1375
Score = 58.9 bits (141), Expect = 2e-08
Identities = 74/301 (24%), Positives = 106/301 (35%), Gaps = 49/301 (16%)
Query: 32 GNNCRDSTLCPAYAT-------CTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDEC 84
G N +D+ C + C NT Y C CKQG ++ ++C D+DEC
Sbjct: 1094 GENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQG-------TYYDPVKLQCFDMDEC 1146
Query: 85 SQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPE 144
Q P C + C N G Y C C +P + + +C E
Sbjct: 1147 -QDPSSC-IDGQCVNTEGSYNCFCTHPMVLDASEKRCI-RPAESNEQIEETDVYQDLCWE 1203
Query: 145 H-SD-------CVNSMGSYS-CSCQVG--FISRNSTCEDVDECADPRACPEHATCNNTV- 192
H SD V +Y+ C C G + + + C D + C T
Sbjct: 1204 HLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPY 1263
Query: 193 ---------GNYSCFCNPGFESSSGHLSFQGLKAS-CEDIDECTEMCPINSTCTNTPGSY 242
Y+ +P F SF+ L+A C ++ C N C Y
Sbjct: 1264 GRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCE-----NGRCVRVQEGY 1318
Query: 243 FCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHP 302
C C G+ ++ D EC DE S C N+ C N GSY C C+ G+ P
Sbjct: 1319 TCDCFDGYHLDTAKMTCVDVN-EC---DELNNRMSLC-KNAKCINTDGSYKCLCLPGYVP 1373
Query: 303 N 303
+
Sbjct: 1374 S 1374
Score = 51.6 bits (122), Expect = 3e-06
Identities = 22/45 (48%), Positives = 31/45 (68%), Gaps = 3/45 (6%)
Query: 121 VPG--KPGNFSCTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGF 163
+PG + N C DINEC VCP + +C+N+MGSY C+C++GF
Sbjct: 287 LPGYKRVNNTFCQDINECQLQGVCP-NGECLNTMGSYRCTCKIGF 330
Score = 43.9 bits (102), Expect = 7e-04
Identities = 24/59 (40%), Positives = 29/59 (49%), Gaps = 10/59 (16%)
Query: 246 CHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNP 304
C PG+ N C+DI+EC Q C PN C N +GSY C C GF P+P
Sbjct: 286 CLPGYKRVNNTF--------CQDINEC-QLQGVC-PNGECLNTMGSYRCTCKIGFGPDP 334
Score = 42.7 bits (99), Expect = 0.001
Identities = 20/36 (55%), Positives = 23/36 (63%), Gaps = 3/36 (8%)
Query: 219 CEDIDECT--EMCPINSTCTNTPGSYFCTCHPGFAP 252
C+DI+EC +CP N C NT GSY CTC GF P
Sbjct: 298 CQDINECQLQGVCP-NGECLNTMGSYRCTCKIGFGP 332
Score = 41.2 bits (95), Expect = 0.004
Identities = 21/49 (42%), Positives = 26/49 (53%), Gaps = 3/49 (6%)
Query: 78 CKDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFS-SPTGNDWVPGKP 125
C+DI+EC Q PN C N G Y+C+C GF PT + VP P
Sbjct: 298 CQDINECQL--QGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPP 344
Score = 40.8 bits (94), Expect = 0.006
Identities = 19/46 (41%), Positives = 27/46 (58%), Gaps = 2/46 (4%)
Query: 159 CQVGFISRNST-CEDVDECADPRACPEHATCNNTVGNYSCFCNPGF 203
C G+ N+T C+D++EC CP + C NT+G+Y C C GF
Sbjct: 286 CLPGYKRVNNTFCQDINECQLQGVCP-NGECLNTMGSYRCTCKIGF 330
Score = 32.3 bits (72), Expect = 2.0
Identities = 14/30 (46%), Positives = 17/30 (56%), Gaps = 1/30 (3%)
Query: 33 NNCRDSTLCPAYATCTNTVDSYYCACKQGF 62
N C+ +CP C NT+ SY C CK GF
Sbjct: 302 NECQLQGVCPN-GECLNTMGSYRCTCKIGF 330
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.135 0.434
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,917,009
Number of Sequences: 37866
Number of extensions: 1777560
Number of successful extensions: 11266
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 193
Number of HSP's successfully gapped in prelim test: 150
Number of HSP's that attempted gapping in prelim test: 4502
Number of HSP's gapped (non-prelim): 1744
length of query: 886
length of database: 18,247,518
effective HSP length: 111
effective length of query: 775
effective length of database: 14,044,392
effective search space: 10884403800
effective search space used: 10884403800
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.