Guide to the Human Genome
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Name: THRA Sequence: fasta or formatted (410aa) NCBI GI: 40806160
Description:

thyroid hormone receptor, alpha isoform 1

Referenced in:

Organs and Hormones
Nuclear Receptors
Retroviral Oncogene Homologs
Thyroid and Thyroid Hormone Receptor

Other entries for this name:
alt prot [490aa] thyroid hormone receptor, alpha isoform 2
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.4         22           2
 C cysteine            4.6         19           2
 D aspartate           6.6         27           2
 E glutamate           7.8         32           2
 F phenylalanine       3.9         16           2
 G glycine             4.9         20           2
 H histidine           2.7         11           1
 I isoleucine          5.4         22           2
 K lysine              8.3         34           2
 L leucine             9.3         38           2
 M methionine          3.4         14           1
 N asparagine          2.4         10           1
 P proline             4.9         20           2
 Q glutamine           4.1         17           2
 R arginine            6.6         27           3
 S serine              6.8         28           1
 T threonine           4.4         18           1
 V valine              5.6         23           2
 W tryptophan          0.7          3           1
 Y tyrosine            2.2          9           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   thyroid hormone receptor, alpha isoform 1 
THRA                  0.900   thyroid hormone receptor, alpha isoform 2 
THRB                  0.770   thyroid hormone receptor, beta 
THRB                  0.770   thyroid hormone receptor, beta 
THRB                  0.770   thyroid hormone receptor, beta 
RARB                  0.275   retinoic acid receptor, beta isoform 1 
RARA                  0.274   retinoic acid receptor, alpha isoform 1 
RARA                  0.274   retinoic acid receptor, alpha isoform 2 
RARA                  0.274   retinoic acid receptor, alpha isoform 1 
RARG                  0.267   retinoic acid receptor, gamma isoform 2 
RARG                  0.267   retinoic acid receptor, gamma isoform 1 
RARB                  0.217   retinoic acid receptor, beta isoform 2 
NR1H3                 0.209   nuclear receptor subfamily 1, group H, member 3 iso...
NR1H3                 0.209   nuclear receptor subfamily 1, group H, member 3 iso...
NR1H2                 0.190   nuclear receptor subfamily 1, group H, member 2 [Hom...
NR1H4                 0.187   nuclear receptor subfamily 1, group H, member 4 [Homo...
RARA                  0.169   retinoic acid receptor, alpha isoform 4 
RXRA                  0.169   retinoid X receptor, alpha 
NR1I3                 0.168   constitutive androstane receptor isoform 3 
NR1I3                 0.163   constitutive androstane receptor isoform 2 
NR4A2                 0.162   nuclear receptor subfamily 4, group A, member 2 [Homo...
VDR                   0.160   vitamin D (1,25-dihydroxyvitamin D3) receptor 
VDR                   0.160   vitamin D (1,25-dihydroxyvitamin D3) receptor 
NR1I2                 0.160   nuclear receptor subfamily 1, group I, member 2 isof...
NR1I3                 0.158   constitutive androstane receptor isoform 1 
NR1I3                 0.154   constitutive androstane receptor isoform 6 
NR1I3                 0.154   constitutive androstane receptor isoform 7 
RXRB                  0.153   retinoid X receptor, beta 
ESRRG                 0.146   estrogen-related receptor gamma isoform 2 
ESRRG                 0.146   estrogen-related receptor gamma isoform 2 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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