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Search of human proteins with 38788416
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38788416 laminin, alpha 1 precursor [Homo sapiens]
(3075 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38788416 laminin, alpha 1 precursor [Homo sapiens] 6382 0.0
gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s... 2861 0.0
gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa... 2855 0.0
gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens] 631 e-180
gi|145309326 laminin, gamma 1 precursor [Homo sapiens] 623 e-178
gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens] 611 e-174
gi|110611156 laminin, gamma 3 precursor [Homo sapiens] 597 e-170
gi|21264602 laminin alpha 5 [Homo sapiens] 513 e-144
gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens] 405 e-112
gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens] 394 e-108
gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens] 394 e-108
gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens] 391 e-108
gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens] 386 e-106
gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens] 358 5e-98
gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens] 358 5e-98
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 353 2e-96
gi|167614504 laminin, beta 1 precursor [Homo sapiens] 338 6e-92
gi|143770880 laminin, beta 4 [Homo sapiens] 289 3e-77
gi|119703755 laminin, beta 2 precursor [Homo sapiens] 284 8e-76
gi|219842266 usherin isoform B [Homo sapiens] 264 1e-69
gi|219842259 usherin isoform A [Homo sapiens] 264 1e-69
gi|148613884 netrin 1 [Homo sapiens] 248 5e-65
gi|62868217 laminin, beta 3 precursor [Homo sapiens] 213 3e-54
gi|62868215 laminin, beta 3 precursor [Homo sapiens] 213 3e-54
gi|189083719 laminin, beta 3 precursor [Homo sapiens] 213 3e-54
gi|93204871 netrin 4 [Homo sapiens] 205 6e-52
gi|5453810 netrin 3 [Homo sapiens] 190 2e-47
gi|164414431 netrin G1 isoform 1 [Homo sapiens] 171 1e-41
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 167 1e-40
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] 165 7e-40
>gi|38788416 laminin, alpha 1 precursor [Homo sapiens]
Length = 3075
Score = 6382 bits (16558), Expect = 0.0
Identities = 3075/3075 (100%), Positives = 3075/3075 (100%)
Query: 1 MRGGVLLVLLLCVAAQCRQRGLFPAILNLASNAHISTNATCGEKGPEMFCKLVEHVPGRP 60
MRGGVLLVLLLCVAAQCRQRGLFPAILNLASNAHISTNATCGEKGPEMFCKLVEHVPGRP
Sbjct: 1 MRGGVLLVLLLCVAAQCRQRGLFPAILNLASNAHISTNATCGEKGPEMFCKLVEHVPGRP 60
Query: 61 VRNPQCRICDGNSANPRERHPISHAIDGTNNWWQSPSIQNGREYHWVTITLDLRQVFQVA 120
VRNPQCRICDGNSANPRERHPISHAIDGTNNWWQSPSIQNGREYHWVTITLDLRQVFQVA
Sbjct: 61 VRNPQCRICDGNSANPRERHPISHAIDGTNNWWQSPSIQNGREYHWVTITLDLRQVFQVA 120
Query: 121 YVIIKAANAPRPGNWILERSLDGTTFSPWQYYAVSDSECLSRYNITPRRGPPTYRADDEV 180
YVIIKAANAPRPGNWILERSLDGTTFSPWQYYAVSDSECLSRYNITPRRGPPTYRADDEV
Sbjct: 121 YVIIKAANAPRPGNWILERSLDGTTFSPWQYYAVSDSECLSRYNITPRRGPPTYRADDEV 180
Query: 181 ICTSYYSRLVPLEHGEIHTSLINGRPSADDLSPKLLEFTSARYIRLRLQRIRTLNADLMT 240
ICTSYYSRLVPLEHGEIHTSLINGRPSADDLSPKLLEFTSARYIRLRLQRIRTLNADLMT
Sbjct: 181 ICTSYYSRLVPLEHGEIHTSLINGRPSADDLSPKLLEFTSARYIRLRLQRIRTLNADLMT 240
Query: 241 LSHREPKELDPIVTRRYYYSIKDISVGGMCICYGHASSCPWDETTKKLQCQCEHNTCGES 300
LSHREPKELDPIVTRRYYYSIKDISVGGMCICYGHASSCPWDETTKKLQCQCEHNTCGES
Sbjct: 241 LSHREPKELDPIVTRRYYYSIKDISVGGMCICYGHASSCPWDETTKKLQCQCEHNTCGES 300
Query: 301 CNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGV 360
CNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGV
Sbjct: 301 CNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGV 360
Query: 361 CINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHN 420
CINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHN
Sbjct: 361 CINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHN 420
Query: 421 GKQPGQCPCKEGYTGEKCDRCQLGYKDYPTCVSCGCNPVGSASDEPCTGPCVCKENVEGK 480
GKQPGQCPCKEGYTGEKCDRCQLGYKDYPTCVSCGCNPVGSASDEPCTGPCVCKENVEGK
Sbjct: 421 GKQPGQCPCKEGYTGEKCDRCQLGYKDYPTCVSCGCNPVGSASDEPCTGPCVCKENVEGK 480
Query: 481 ACDRCKPGFYNLKEKNPRGCSECFCFGVSDVCSSLSWPVGQVNSMSGWLVTDLISPRKIP 540
ACDRCKPGFYNLKEKNPRGCSECFCFGVSDVCSSLSWPVGQVNSMSGWLVTDLISPRKIP
Sbjct: 481 ACDRCKPGFYNLKEKNPRGCSECFCFGVSDVCSSLSWPVGQVNSMSGWLVTDLISPRKIP 540
Query: 541 SQQDALGGRHQVSINNTAVMQRLAPKYYWAAPEAYLGNKLTAFGGFLKYTVSYDIPVETV 600
SQQDALGGRHQVSINNTAVMQRLAPKYYWAAPEAYLGNKLTAFGGFLKYTVSYDIPVETV
Sbjct: 541 SQQDALGGRHQVSINNTAVMQRLAPKYYWAAPEAYLGNKLTAFGGFLKYTVSYDIPVETV 600
Query: 601 DSNLMSHADVIIKGNGLTLSTQAEGLSLQPYEEYLNVVRLVPENFQDFHSKRQIDRDQLM 660
DSNLMSHADVIIKGNGLTLSTQAEGLSLQPYEEYLNVVRLVPENFQDFHSKRQIDRDQLM
Sbjct: 601 DSNLMSHADVIIKGNGLTLSTQAEGLSLQPYEEYLNVVRLVPENFQDFHSKRQIDRDQLM 660
Query: 661 TVLANVTHLLIRANYNSAKMALYRLESVSLDIASSNAIDLVVAADVEHCECPQGYTGTSC 720
TVLANVTHLLIRANYNSAKMALYRLESVSLDIASSNAIDLVVAADVEHCECPQGYTGTSC
Sbjct: 661 TVLANVTHLLIRANYNSAKMALYRLESVSLDIASSNAIDLVVAADVEHCECPQGYTGTSC 720
Query: 721 ESCLSGYYRVDGILFGGICQPCECHGHAAECNVHGVCIACAHNTTGVHCEQCLPGFYGEP 780
ESCLSGYYRVDGILFGGICQPCECHGHAAECNVHGVCIACAHNTTGVHCEQCLPGFYGEP
Sbjct: 721 ESCLSGYYRVDGILFGGICQPCECHGHAAECNVHGVCIACAHNTTGVHCEQCLPGFYGEP 780
Query: 781 SRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNPT 840
SRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNPT
Sbjct: 781 SRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNPT 840
Query: 841 VPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCADGFYGDAVTAKNCR 900
VPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCADGFYGDAVTAKNCR
Sbjct: 841 VPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCADGFYGDAVTAKNCR 900
Query: 901 ACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLDSGHGCRPCNCSVAGSVS 960
ACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLDSGHGCRPCNCSVAGSVS
Sbjct: 901 ACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLDSGHGCRPCNCSVAGSVS 960
Query: 961 DGCTDEGQCHCVPGVAGKRCDRCAHGFYAYQDGSCTPCDCPHTQNTCDPETGECVCPPHT 1020
DGCTDEGQCHCVPGVAGKRCDRCAHGFYAYQDGSCTPCDCPHTQNTCDPETGECVCPPHT
Sbjct: 961 DGCTDEGQCHCVPGVAGKRCDRCAHGFYAYQDGSCTPCDCPHTQNTCDPETGECVCPPHT 1020
Query: 1021 QGVKCEECEDGHWGYDAEVGCQACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLG 1080
QGVKCEECEDGHWGYDAEVGCQACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLG
Sbjct: 1021 QGVKCEECEDGHWGYDAEVGCQACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLG 1080
Query: 1081 YRDFPDCVPCDCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFALR 1140
YRDFPDCVPCDCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFALR
Sbjct: 1081 YRDFPDCVPCDCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFALR 1140
Query: 1141 ADNPLGCSPCFCSGLSHLCSELEDYVRTPVTLGSDQPLLRVVSQSNLRGTTEGVYYQAPD 1200
ADNPLGCSPCFCSGLSHLCSELEDYVRTPVTLGSDQPLLRVVSQSNLRGTTEGVYYQAPD
Sbjct: 1141 ADNPLGCSPCFCSGLSHLCSELEDYVRTPVTLGSDQPLLRVVSQSNLRGTTEGVYYQAPD 1200
Query: 1201 FLLDAATVRQHIRAEPFYWRLPQQFQGDQLMAYGGKLKYSVAFYSLDGVGTSNFEPQVLI 1260
FLLDAATVRQHIRAEPFYWRLPQQFQGDQLMAYGGKLKYSVAFYSLDGVGTSNFEPQVLI
Sbjct: 1201 FLLDAATVRQHIRAEPFYWRLPQQFQGDQLMAYGGKLKYSVAFYSLDGVGTSNFEPQVLI 1260
Query: 1261 KGGRIRKQVIYMDAPAPENGVRQEQEVAMRENFWKYFNSVSEKPVTREDFMSVLSDIEYI 1320
KGGRIRKQVIYMDAPAPENGVRQEQEVAMRENFWKYFNSVSEKPVTREDFMSVLSDIEYI
Sbjct: 1261 KGGRIRKQVIYMDAPAPENGVRQEQEVAMRENFWKYFNSVSEKPVTREDFMSVLSDIEYI 1320
Query: 1321 LIKASYGQGLQQSRISDISMEVGRKAEKLHPEEEVASLLENCVCPPGTVGFSCQDCAPGY 1380
LIKASYGQGLQQSRISDISMEVGRKAEKLHPEEEVASLLENCVCPPGTVGFSCQDCAPGY
Sbjct: 1321 LIKASYGQGLQQSRISDISMEVGRKAEKLHPEEEVASLLENCVCPPGTVGFSCQDCAPGY 1380
Query: 1381 HRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKCLNCGDNTAGDHCDVCTSGYYG 1440
HRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKCLNCGDNTAGDHCDVCTSGYYG
Sbjct: 1381 HRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKCLNCGDNTAGDHCDVCTSGYYG 1440
Query: 1441 KVTGSASDCALCACPHSPPASFSPTCVLEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQ 1500
KVTGSASDCALCACPHSPPASFSPTCVLEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQ
Sbjct: 1441 KVTGSASDCALCACPHSPPASFSPTCVLEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQ 1500
Query: 1501 TPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDECEPRHILMETDCVSCDDEC 1560
TPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDECEPRHILMETDCVSCDDEC
Sbjct: 1501 TPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDECEPRHILMETDCVSCDDEC 1560
Query: 1561 VGVLLNDLDEIGDAVLSLNLTGIIPVPYGILSNLENTTKYLQESLLKENMQKDLGKIKLE 1620
VGVLLNDLDEIGDAVLSLNLTGIIPVPYGILSNLENTTKYLQESLLKENMQKDLGKIKLE
Sbjct: 1561 VGVLLNDLDEIGDAVLSLNLTGIIPVPYGILSNLENTTKYLQESLLKENMQKDLGKIKLE 1620
Query: 1621 GVAEETDNLQKKLTRMLASTQKVNRATERIFKESQDLAIAIERLQMSITEIMEKTTLNQT 1680
GVAEETDNLQKKLTRMLASTQKVNRATERIFKESQDLAIAIERLQMSITEIMEKTTLNQT
Sbjct: 1621 GVAEETDNLQKKLTRMLASTQKVNRATERIFKESQDLAIAIERLQMSITEIMEKTTLNQT 1680
Query: 1681 LDEDFLLPNSTLQNMQQNGTSLLEIMQIRDFTQLHQNATLELKAAEDLLSQIQENYQKPL 1740
LDEDFLLPNSTLQNMQQNGTSLLEIMQIRDFTQLHQNATLELKAAEDLLSQIQENYQKPL
Sbjct: 1681 LDEDFLLPNSTLQNMQQNGTSLLEIMQIRDFTQLHQNATLELKAAEDLLSQIQENYQKPL 1740
Query: 1741 EELEVLKEAASHVLSKHNNELKAAEALVREAEAKMQESNHLLLMVNANLREFSDKKLHVQ 1800
EELEVLKEAASHVLSKHNNELKAAEALVREAEAKMQESNHLLLMVNANLREFSDKKLHVQ
Sbjct: 1741 EELEVLKEAASHVLSKHNNELKAAEALVREAEAKMQESNHLLLMVNANLREFSDKKLHVQ 1800
Query: 1801 EEQNLTSELIVQGRGLIDAAAAQTDAVQDALEHLEDHQDKLLLWSAKIRHHIDDLVMHMS 1860
EEQNLTSELIVQGRGLIDAAAAQTDAVQDALEHLEDHQDKLLLWSAKIRHHIDDLVMHMS
Sbjct: 1801 EEQNLTSELIVQGRGLIDAAAAQTDAVQDALEHLEDHQDKLLLWSAKIRHHIDDLVMHMS 1860
Query: 1861 QRNAVDLVYRAEDHAAEFQRLADVLYSGLENIRNVSLNATSAAYVHYNIQSLIEESEELA 1920
QRNAVDLVYRAEDHAAEFQRLADVLYSGLENIRNVSLNATSAAYVHYNIQSLIEESEELA
Sbjct: 1861 QRNAVDLVYRAEDHAAEFQRLADVLYSGLENIRNVSLNATSAAYVHYNIQSLIEESEELA 1920
Query: 1921 RDAHRTVTETSLLSESLVSNGKAAVQRSSRFLKEGNNLSRKLPGIALELSELRNKTNRFQ 1980
RDAHRTVTETSLLSESLVSNGKAAVQRSSRFLKEGNNLSRKLPGIALELSELRNKTNRFQ
Sbjct: 1921 RDAHRTVTETSLLSESLVSNGKAAVQRSSRFLKEGNNLSRKLPGIALELSELRNKTNRFQ 1980
Query: 1981 ENAVEITRQTNESLLILRAIPKGIRDKGAKTKELATSASQSAVSTLRDVAGLSQELLNTS 2040
ENAVEITRQTNESLLILRAIPKGIRDKGAKTKELATSASQSAVSTLRDVAGLSQELLNTS
Sbjct: 1981 ENAVEITRQTNESLLILRAIPKGIRDKGAKTKELATSASQSAVSTLRDVAGLSQELLNTS 2040
Query: 2041 ASLSRVNTTLRETHQLLQDSTMATLLAGRKVKDVEIQANLLFDRLKPLKMLEENLSRNLS 2100
ASLSRVNTTLRETHQLLQDSTMATLLAGRKVKDVEIQANLLFDRLKPLKMLEENLSRNLS
Sbjct: 2041 ASLSRVNTTLRETHQLLQDSTMATLLAGRKVKDVEIQANLLFDRLKPLKMLEENLSRNLS 2100
Query: 2101 EIKLLISQARKQAASIKVAVSADRDCIRAYQPQISSTNYNTLTLNVKTQEPDNLLFYLGS 2160
EIKLLISQARKQAASIKVAVSADRDCIRAYQPQISSTNYNTLTLNVKTQEPDNLLFYLGS
Sbjct: 2101 EIKLLISQARKQAASIKVAVSADRDCIRAYQPQISSTNYNTLTLNVKTQEPDNLLFYLGS 2160
Query: 2161 STASDFLAVEMRRGRVAFLWDLGSGSTRLEFPDFPIDDNRWHSIHVARFGNIGSLSVKEM 2220
STASDFLAVEMRRGRVAFLWDLGSGSTRLEFPDFPIDDNRWHSIHVARFGNIGSLSVKEM
Sbjct: 2161 STASDFLAVEMRRGRVAFLWDLGSGSTRLEFPDFPIDDNRWHSIHVARFGNIGSLSVKEM 2220
Query: 2221 SSNQKSPTKTSKSPGTANVLDVNNSTLMFVGGLGGQIKKSPAVKVTHFKGCLGEAFLNGK 2280
SSNQKSPTKTSKSPGTANVLDVNNSTLMFVGGLGGQIKKSPAVKVTHFKGCLGEAFLNGK
Sbjct: 2221 SSNQKSPTKTSKSPGTANVLDVNNSTLMFVGGLGGQIKKSPAVKVTHFKGCLGEAFLNGK 2280
Query: 2281 SIGLWNYIEREGKCRGCFGSSQNEDPSFHFDGSGYSVVEKSLPATVTQIIMLFNTFSPNG 2340
SIGLWNYIEREGKCRGCFGSSQNEDPSFHFDGSGYSVVEKSLPATVTQIIMLFNTFSPNG
Sbjct: 2281 SIGLWNYIEREGKCRGCFGSSQNEDPSFHFDGSGYSVVEKSLPATVTQIIMLFNTFSPNG 2340
Query: 2341 LLLYLGSYGTKDFLSIELFRGRVKVMTDLGSGPITLLTDRRYNNGTWYKIAFQRNRKQGV 2400
LLLYLGSYGTKDFLSIELFRGRVKVMTDLGSGPITLLTDRRYNNGTWYKIAFQRNRKQGV
Sbjct: 2341 LLLYLGSYGTKDFLSIELFRGRVKVMTDLGSGPITLLTDRRYNNGTWYKIAFQRNRKQGV 2400
Query: 2401 LAVIDAYNTSNKETKQGETPGASSDLNRLDKDPIYVGGLPRSRVVRRGVTTKSFVGCIKN 2460
LAVIDAYNTSNKETKQGETPGASSDLNRLDKDPIYVGGLPRSRVVRRGVTTKSFVGCIKN
Sbjct: 2401 LAVIDAYNTSNKETKQGETPGASSDLNRLDKDPIYVGGLPRSRVVRRGVTTKSFVGCIKN 2460
Query: 2461 LEISRSTFDLLRNSYGVRKGCLLEPIRSVSFLKGGYIELPPKSLSPESEWLVTFATTNSS 2520
LEISRSTFDLLRNSYGVRKGCLLEPIRSVSFLKGGYIELPPKSLSPESEWLVTFATTNSS
Sbjct: 2461 LEISRSTFDLLRNSYGVRKGCLLEPIRSVSFLKGGYIELPPKSLSPESEWLVTFATTNSS 2520
Query: 2521 GIILAALGGDVEKRGDREEAHVPFFSVMLIGGNIEVHVNPGDGTGLRKALLHAPTGTCSD 2580
GIILAALGGDVEKRGDREEAHVPFFSVMLIGGNIEVHVNPGDGTGLRKALLHAPTGTCSD
Sbjct: 2521 GIILAALGGDVEKRGDREEAHVPFFSVMLIGGNIEVHVNPGDGTGLRKALLHAPTGTCSD 2580
Query: 2581 GQAHSISLVRNRRIITVQLDENNPVEMKLGTLVESRTINVSNLYVGGIPEGEGTSLLTMR 2640
GQAHSISLVRNRRIITVQLDENNPVEMKLGTLVESRTINVSNLYVGGIPEGEGTSLLTMR
Sbjct: 2581 GQAHSISLVRNRRIITVQLDENNPVEMKLGTLVESRTINVSNLYVGGIPEGEGTSLLTMR 2640
Query: 2641 RSFHGCIKNLIFNLELLDFNSAVGHEQVDLDTCWLSERPKLAPDAEDSKLLPEPRAFPEQ 2700
RSFHGCIKNLIFNLELLDFNSAVGHEQVDLDTCWLSERPKLAPDAEDSKLLPEPRAFPEQ
Sbjct: 2641 RSFHGCIKNLIFNLELLDFNSAVGHEQVDLDTCWLSERPKLAPDAEDSKLLPEPRAFPEQ 2700
Query: 2701 CVVDAALEYVPGAHQFGLTQNSHFILPFNQSAVRKKLSVELSIRTFASSGLIYYMAHQNQ 2760
CVVDAALEYVPGAHQFGLTQNSHFILPFNQSAVRKKLSVELSIRTFASSGLIYYMAHQNQ
Sbjct: 2701 CVVDAALEYVPGAHQFGLTQNSHFILPFNQSAVRKKLSVELSIRTFASSGLIYYMAHQNQ 2760
Query: 2761 ADYAVLQLHGGRLHFMFDLGKGRTKVSHPALLSDGKWHTVKTDYVKRKGFITVDGRESPM 2820
ADYAVLQLHGGRLHFMFDLGKGRTKVSHPALLSDGKWHTVKTDYVKRKGFITVDGRESPM
Sbjct: 2761 ADYAVLQLHGGRLHFMFDLGKGRTKVSHPALLSDGKWHTVKTDYVKRKGFITVDGRESPM 2820
Query: 2821 VTVVGDGTMLDVEGLFYLGGLPSQYQARKIGNITHSIPACIGDVTVNSKQLDKDSPVSAF 2880
VTVVGDGTMLDVEGLFYLGGLPSQYQARKIGNITHSIPACIGDVTVNSKQLDKDSPVSAF
Sbjct: 2821 VTVVGDGTMLDVEGLFYLGGLPSQYQARKIGNITHSIPACIGDVTVNSKQLDKDSPVSAF 2880
Query: 2881 TVNRCYAVAQEGTYFDGSGYAALVKEGYKVQSDVNITLEFRTSSQNGVLLGISTAKVDAI 2940
TVNRCYAVAQEGTYFDGSGYAALVKEGYKVQSDVNITLEFRTSSQNGVLLGISTAKVDAI
Sbjct: 2881 TVNRCYAVAQEGTYFDGSGYAALVKEGYKVQSDVNITLEFRTSSQNGVLLGISTAKVDAI 2940
Query: 2941 GLELVDGKVLFHVNNGAGRITAAYEPKTATVLCDGKWHTLQANKSKHRITLIVDGNAVGA 3000
GLELVDGKVLFHVNNGAGRITAAYEPKTATVLCDGKWHTLQANKSKHRITLIVDGNAVGA
Sbjct: 2941 GLELVDGKVLFHVNNGAGRITAAYEPKTATVLCDGKWHTLQANKSKHRITLIVDGNAVGA 3000
Query: 3001 ESPHTQSTSVDTNNPIYVGGYPAGVKQKCLRSQTSFRGCLRKLALIKSPQVQSFDFSRAF 3060
ESPHTQSTSVDTNNPIYVGGYPAGVKQKCLRSQTSFRGCLRKLALIKSPQVQSFDFSRAF
Sbjct: 3001 ESPHTQSTSVDTNNPIYVGGYPAGVKQKCLRSQTSFRGCLRKLALIKSPQVQSFDFSRAF 3060
Query: 3061 ELHGVFLHSCPGTES 3075
ELHGVFLHSCPGTES
Sbjct: 3061 ELHGVFLHSCPGTES 3075
>gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo
sapiens]
Length = 3118
Score = 2861 bits (7417), Expect = 0.0
Identities = 1436/3131 (45%), Positives = 1989/3131 (63%), Gaps = 83/3131 (2%)
Query: 4 GVLLVLLLC-----VAAQC----------RQRGLFPAILNLASNAHISTNATCGEKGPEM 48
GVLL+LLL V AQ +QRGLFPA+LNLASNA I+TNATCGEKGPEM
Sbjct: 6 GVLLLLLLSGGLGGVQAQRPQQQRQSQAHQQRGLFPAVLNLASNALITTNATCGEKGPEM 65
Query: 49 FCKLVEHVPGRPVRNPQCRICDGNSANPRERHPISHAIDGTNNWWQSPSIQNGREYHWVT 108
+CKLVEHVPG+PVRNPQCRIC+ NS+NP +RHPI++AIDG N WWQSPSI+NG EYH+VT
Sbjct: 66 YCKLVEHVPGQPVRNPQCRICNQNSSNPNQRHPITNAIDGKNTWWQSPSIKNGIEYHYVT 125
Query: 109 ITLDLRQVFQVAYVIIKAANAPRPGNWILERSLDGTTFSPWQYYAVSDSECLSRYNITPR 168
ITLDL+QVFQ+AYVI+KAAN+PRPGNWILERSLD + PWQY+AV+D+ECL+ YNI PR
Sbjct: 126 ITLDLQQVFQIAYVIVKAANSPRPGNWILERSLDDVEYKPWQYHAVTDTECLTLYNIYPR 185
Query: 169 RGPPTYRADDEVICTSYYSRLVPLEHGEIHTSLINGRPSADDLSPKLLEFTSARYIRLRL 228
GPP+Y DDEVICTS+YS++ PLE+GEIH SLINGRPSADD SP+LLEFTSARYIRLR
Sbjct: 186 TGPPSYAKDDEVICTSFYSKIHPLENGEIHISLINGRPSADDPSPELLEFTSARYIRLRF 245
Query: 229 QRIRTLNADLMTLSHREPKELDPIVTRRYYYSIKDISVGGMCICYGHASSCPWDETTKKL 288
QRIRTLNADLM +H++P+E+DPIVTRRYYYS+KDISVGGMCICYGHA +CP D T K
Sbjct: 246 QRIRTLNADLMMFAHKDPREIDPIVTRRYYYSVKDISVGGMCICYGHARACPLDPATNKS 305
Query: 289 QCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKS 348
+C+CEHNTCG+SC++CCPG+HQ+PWR GT + CEACNCH KA++CYYDE+VA++ S
Sbjct: 306 RCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLS 365
Query: 349 LNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSV 408
LN G++ GGGVCINC QNT GINCETC DG++RP VSP PC+PC+CDP+GSL+ V
Sbjct: 366 LNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEV 425
Query: 409 CIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYPTCVSCGCNPVGSASDEPCT 468
C+KD+ H+ G PG C CK G+ G CDRC GY YP C +C C+ +GS +++PC
Sbjct: 426 CVKDEKHA--RRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKNEDPCF 483
Query: 469 GPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFCFGVSDVCSSLSWPVGQVNSMSGW 528
GPC+CKENVEG C RCK GF+NL+E N +GC ECFC GVS+ C S W G++ MSGW
Sbjct: 484 GPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCSGVSNRCQSSYWTYGKIQDMSGW 543
Query: 529 LVTDLISPRKIPSQQDALGGRHQVSINNTAVMQRLAPKYYWAAPEAYLGNKLTAFGGFLK 588
+TDL ++ QQD L Q+SI+N Q L YYW+AP YLGNKL A GG L
Sbjct: 544 YLTDLPGRIRVAPQQDDLDSPQQISISNAEARQALPHSYYWSAPAPYLGNKLPAVGGQLT 603
Query: 589 YTVSYDIPVETVDSNLMSHADVIIKGNGLTLSTQAEGLSLQPYEEYLNVVRLVPENFQDF 648
+T+SYD+ E D+ + +I++GN L++ST + + L P EE+ NV+ L E+F
Sbjct: 604 FTISYDLEEEEEDTERVLQLMIILEGNDLSISTAQDEVYLHPSEEHTNVLLLKEESFTIH 663
Query: 649 HSKRQIDRDQLMTVLANVTHLLIRANYNSAKMALYRLESVSLDIASSNAIDLVVAADVEH 708
+ + R + MTVLAN+ +L++ Y+ A++RL SV+L+ A S D +AA VE
Sbjct: 664 GTHFPVRRKEFMTVLANLKRVLLQITYSFGMDAIFRLSSVNLESAVSYPTDGSIAAAVEV 723
Query: 709 CECPQGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAAEC-NVHGVCIACAHNTTGV 767
C+CP GYTG+SCESC + RV+G +FGGIC+PC+C GHA C +V G C+ C +T G
Sbjct: 724 CQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLNCKDHTGGP 783
Query: 768 HCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYSGAW 827
+C++CLPGFYGEP++GT DCQPCACPL I SNNFSPTCHL+ ++CD C GY+G
Sbjct: 784 YCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPR 843
Query: 828 CERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCAD 887
CERCA+GY+G P+VPG SC PC C+ N+D S G CDS++G CL C T G +CE CAD
Sbjct: 844 CERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCAD 903
Query: 888 GFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLDSGHG 947
G++GDAV AKNC+ C C+ GS S VCH +TG C+C+ NV GQ+CD+C G +GL S G
Sbjct: 904 GYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARG 963
Query: 948 CRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCDRCAHGFYAYQDGSCTPCDCPHTQNTC 1007
C PCNC+ GS S C + GQC C PGV GK+CDRCAHG++ +Q+G CT C+C H N C
Sbjct: 964 CVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNNC 1023
Query: 1008 DPETGECVCPPHTQGVKCEECEDGHWGYDAEVGCQACNCSLVGSTHHRCDVVTGHCQCKS 1067
DP+TG C+CPP+T G KC +C WG+ GC+ACNCS VGS +C+V TG C C
Sbjct: 1024 DPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCNCHP 1083
Query: 1068 KFGGRACDQCSLGYRDFPDCVPCDCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGP 1127
KF G C +CS G+ ++P C CDC L GT C+ E C C ++TG C CK NV G
Sbjct: 1084 KFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGI 1143
Query: 1128 QCNECREGTFALRADNPLGCSPCFCSGLSHLCSELEDYVRTPVTLGSDQPLLRVVSQSNL 1187
C+ CR G F L A NPLGCS C+C G + CSE + +RT VTL ++Q +L +V ++
Sbjct: 1144 HCDRCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGLIRTWVTLKAEQTILPLVDEALQ 1203
Query: 1188 RGTTEGVYYQAPDFLLDAATVRQHIRAEPFYWRLPQQFQGDQLMAYGGKLKYSVAFYSLD 1247
TT+G+ +Q P+ + +R+ + EPFYW+LP+QF+G +LMAYGGKLKY++ F + +
Sbjct: 1204 HTTTKGIVFQHPEIVAHMDLMREDLHLEPFYWKLPEQFEGKKLMAYGGKLKYAIYFEARE 1263
Query: 1248 GVGTSNFEPQVLIKGGR-IRKQVIYMDAPAPENGVRQEQEVAMRENFWKYFNSVS--EKP 1304
G S + PQV+I+GG ++I AP G E+ M E WKY+ +
Sbjct: 1264 ETGFSTYNPQVIIRGGTPTHARIIVRHMAAPLIGQLTRHEIEMTEKEWKYYGDDPRVHRT 1323
Query: 1305 VTREDFMSVLSDIEYILIKASYGQGLQQSRISDISMEV---GRKAEKLHPEEEVASLLEN 1361
VTREDF+ +L DI YILIKA+YG ++QSRIS+ISMEV GR P A L+E
Sbjct: 1324 VTREDFLDILYDIHYILIKATYGNFMRQSRISEISMEVAEQGRGTTMTPP----ADLIEK 1379
Query: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKCLN 1421
C CP G G SC+ C PG++R + G R P P + CVPC CN HS CDP T C N
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGG-RTPGPTLGTCVPCQCNGHSSLCDPETSICQN 1438
Query: 1422 CGDNTAGDHCDVCTSGYYGKVTGSASDCALCACP-HSPPASFSPTCVLEGDHDFRCDACL 1480
C +TAGD C+ C GYYG V G +DC CACP S +FSP+CV EG D+RC AC
Sbjct: 1439 CQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACP 1498
Query: 1481 LGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLRCD 1540
GYEG++CERC+ Y G+P PGGSCQ+C+C+P+GS+ CD +G C CR GA+G +CD
Sbjct: 1499 RGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCD 1558
Query: 1541 ECEPRHILMETDCVSCDDECVGVLLNDLDEIGDAVLSLNLTGIIPVPYGILSNLENTTKY 1600
C+ H +CV C DEC G+LL DL + V+S+NLTG +P PY +L LEN T+
Sbjct: 1559 GCKHWHAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKMLYGLENMTQE 1618
Query: 1601 LQESLLKENMQK---DLGKIKLEGVAEETDNLQKKLTRMLASTQKVNRATERIFKESQDL 1657
L+ L + + L + L + E + L + T++ A ++ + ER ++ L
Sbjct: 1619 LKHLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSL 1678
Query: 1658 AIAIERLQMSITEIMEKT-TLNQTL---DEDFLLPNSTLQNMQQNGTSLLEIMQIRDFTQ 1713
I+ L + EK LN+TL DE F L+ +Q+ +++ ++ ++
Sbjct: 1679 GEFIKELARDAEAVNEKAIKLNETLGTRDEAF---ERNLEGLQKEIDQMIKELRRKNLET 1735
Query: 1714 LHQNATLELKAAEDLLSQIQENYQKPLEELEVLKEAASHVLSKHNNELKAAEALVREAEA 1773
+ A EL AAE LL ++++ + + E E +++ L+ + N++ A L+REA
Sbjct: 1736 QKEIAEDELVAAEALLKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWDLLREATD 1795
Query: 1774 KMQESNHLLLMVNANLREFSDKKLHVQEEQNLTSELIVQGRGLIDAAAAQTDAVQDALEH 1833
K++E+N L + N+ KK V+ + + +G ++D A D + +++
Sbjct: 1796 KIREANRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLADEINSIIDY 1855
Query: 1834 LEDHQDKLLLWSAKIRHHIDDLVMHMSQRNAVDLVYRAEDHAAEFQRLADVLYSGLENIR 1893
+ED Q KL S ++ IDDL + R + V +AE HAA+ + VL L+ +
Sbjct: 1856 VEDIQTKLPPMSEELNDKIDDLSQEIKDRKLAEKVSQAESHAAQLNDSSAVLDGILDEAK 1915
Query: 1894 NVSLNATSAAYVHYNIQSLIEESEELARDAHRTVTETSLLSES----LVSNGKAAVQRSS 1949
N+S NAT+A + NI+ I+E+E++A++A E + L+ L + K +Q+S
Sbjct: 1916 NISFNATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDAKGCLQKSF 1975
Query: 1950 RFLKEGNNLSRKLPGIALELSELRNKTNRFQENAVEITRQTNESLLILRAIPKGIRDKGA 2009
R L E L+ + L+ L+ + ++ R N++L L AIP K
Sbjct: 1976 RILNEAKKLANDVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIPNDTAAKLQ 2035
Query: 2010 KTKELATSASQSAVSTLRDVAGLSQELLNTSASLSRVNTTLRETHQLLQDSTMATLL--A 2067
K+ A A+ +A L + L Q L + +++ ++ +T+ +++D + ++ A
Sbjct: 2036 AVKDKARQANDTAKDVLAQITELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNKIIADA 2095
Query: 2068 GRKVKDVEIQANLLFDRLKPLKMLEENLSRNLSEIKLLISQARKQAASIKVAVSADRDCI 2127
VK++E +A+ L D+LKP+K LE+NL +N+SEIK LI+QARKQA SIKV+VS+ DCI
Sbjct: 2096 DATVKNLEQEADRLIDKLKPIKELEDNLKKNISEIKELINQARKQANSIKVSVSSGGDCI 2155
Query: 2128 RAYQPQISSTNYNTLTLNVKTQEPDNLLFYLGSSTASDFLAVEMRRGRVAFLWDLGSGST 2187
R Y+P+I +YN + +NVKT DNLLFYLGS+ DFLA+EMR+G+V+FLWD+GSG
Sbjct: 2156 RTYKPEIKKGSYNNIVVNVKTAVADNLLFYLGSAKFIDFLAIEMRKGKVSFLWDVGSGVG 2215
Query: 2188 RLEFPDFPIDDNRWHSIHVARFGNIGSLSVKEMSSNQKS---PTKTSKSPGTANVLDVNN 2244
R+E+PD IDD+ W+ I +R G G++SV+ + + S T S SP +LDV+
Sbjct: 2216 RVEYPDLTIDDSYWYRIVASRTGRNGTISVRALDGPKASIVPSTHHSTSPPGYTILDVDA 2275
Query: 2245 STLMFVGGLGGQIKKSPAVKVTHFKGCLGEAFLNGKSIGLWNYIEREGKCRGCFGSSQNE 2304
+ ++FVGGL G++KK+ AV+V F GC+GE + + K IGLWN+ E+EG C+GC S Q E
Sbjct: 2276 NAMLFVGGLTGKLKKADAVRVITFTGCMGETYFDNKPIGLWNFREKEGDCKGCTVSPQVE 2335
Query: 2305 DP--SFHFDGSGYSVVEKSLP--ATVTQIIMLFNTFSPNGLLLYLGSYGTKDFLSIELFR 2360
D + FDG GY++V + + ++ ++ F TFS + LL+YL + +DF+S+EL
Sbjct: 2336 DSEGTIQFDGEGYALVSRPIRWYPNISTVMFKFRTFSSSALLMYLATRDLRDFMSVELTD 2395
Query: 2361 GRVKVMTDLGSGPITLLTDRRYNNGTWYKIAFQRNRKQGVLAVIDAYNTSNKETKQGETP 2420
G +KV DLGSG ++++++ +N+G W R +KQ ++++D +T+ +E +
Sbjct: 2396 GHIKVSYDLGSGMASVVSNQNHNDGKWKSFTLSRIQKQANISIVD-IDTNQEENIATSSS 2454
Query: 2421 GASSDLNRLDKDPIYVGGLPRSRVVRRGVTTKSFVGCIKNLEISRSTFDLLRNS--YGVR 2478
G + L+ D IY GGLP R +R V K + GC+K++EISR+ +++L + GV
Sbjct: 2455 GNNFGLDLKADDKIYFGGLPTLRNLRPEVNLKKYSGCLKDIEISRTPYNILSSPDYVGVT 2514
Query: 2479 KGCLLEPIRSVSFLKGGYIELPPKSLSPESEWLVTFATTNSSGIILAALGG-DVEKRGDR 2537
KGC LE + +VSF K G++EL P + +E ++F+T N SGIIL GG R R
Sbjct: 2515 KGCSLENVYTVSFPKPGFVELSPVPIDVGTEINLSFSTKNESGIILLGSGGTPAPPRRKR 2574
Query: 2538 EEAHVPFFSVMLIGGNIEVHVNPGDGTGLRKALLHAPTGTCSDGQAHSISLVRNRRIITV 2597
+ ++ ++L G +EVH++ G T +RK ++ DG+ HS+ + R R I TV
Sbjct: 2575 RQTGQAYYVILLNRGRLEVHLSTGART-MRKIVIRPEPNLFHDGREHSVHVERTRGIFTV 2633
Query: 2598 QLDENNPVEMKLGTLVESRTINVSNLYVGGIPEGEGTSLLTMRRSFHGCIKNLIFNLELL 2657
Q+DEN + L + I V L+VGG P S L F GCI NL+ N +
Sbjct: 2634 QVDEN---RRYMQNLTVEQPIEVKKLFVGGAPPEFQPSPLRNIPPFEGCIWNLVINSVPM 2690
Query: 2658 DFNSAVGHEQVDLDTCWLSERPKLAPDAEDSK-----LLPEP---RAFPE--------QC 2701
DF V + D+ C KL D + + + PEP AFP C
Sbjct: 2691 DFARPVSFKNADIGRC---AHQKLREDEDGAAPAEIVIQPEPVPTPAFPTPTPVLTHGPC 2747
Query: 2702 VVDAALEYVPGAHQFGLTQNSHFILPFNQSAVRKKLSVELSIRTFASSGLIYYMAHQNQA 2761
++ + G+ QFGL++NSH + F+ + V+ +L++EL +RT A SGL++YMA N A
Sbjct: 2748 AAESEPALLIGSKQFGLSRNSHIAIAFDDTKVKNRLTIELEVRTEAESGLLFYMARINHA 2807
Query: 2762 DYAVLQLHGGRLHFMFDLGKGRTKVSHPALLSDGKWHTVKTDYVKRKGFITVDGRESPMV 2821
D+A +QL G +F +DLG G T P ++DG+WH +K K++G + VDG + +
Sbjct: 2808 DFATVQLRNGLPYFSYDLGSGDTHTMIPTKINDGQWHKIKIMRSKQEGILYVDGASNRTI 2867
Query: 2822 TVVGDGTMLDVEGLFYLGGLPSQYQARKIGNITHSIPACIGDVTVNSKQLDKDSPVSAFT 2881
+ +LDV G+ Y+GGLP Y R+IG +T+SI C+ ++ + D + P S+F
Sbjct: 2868 S-PKKADILDVVGMLYVGGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPTSSFH 2926
Query: 2882 VNRCYAVAQEGTYFDGSGYAALVKEGYKVQSDVNITLEFRTSSQNGVLLGISTAKVDAIG 2941
V C+A AQ GTYFDG+G+A V G+KV D+ + EFRT++ GVLLGIS+ K+D +G
Sbjct: 2927 VGTCFANAQRGTYFDGTGFAKAV-GGFKVGLDLLVEFEFRTTTTTGVLLGISSQKMDGMG 2985
Query: 2942 LELVDGKVLFHVNNGAGRITAAYEPKTATVLCDGKWHTLQANKSKHRITLIVDGNAVGAE 3001
+E++D K++FHV+NGAGR TA Y+ LCDG+WH + ANK KHRI L VDGN V A+
Sbjct: 2986 IEMIDEKLMFHVDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIKHRIELTVDGNQVEAQ 3045
Query: 3002 SPHTQSTSVDTNNPIYVGGYPAGVKQKCLRSQTSFRGCLRKLALIK-SPQVQSFDFSRAF 3060
SP+ STS DTN+P++VGG+P +KQ L + FRGC+R L L K + + +F++A
Sbjct: 3046 SPNPASTSADTNDPVFVGGFPDDLKQFGLTTSIPFRGCIRSLKLTKGTGKPLEVNFAKAL 3105
Query: 3061 ELHGVFLHSCP 3071
EL GV SCP
Sbjct: 3106 ELRGVQPVSCP 3116
>gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo
sapiens]
Length = 3122
Score = 2855 bits (7402), Expect = 0.0
Identities = 1436/3135 (45%), Positives = 1988/3135 (63%), Gaps = 87/3135 (2%)
Query: 4 GVLLVLLLC-----VAAQC----------RQRGLFPAILNLASNAHISTNATCGEKGPEM 48
GVLL+LLL V AQ +QRGLFPA+LNLASNA I+TNATCGEKGPEM
Sbjct: 6 GVLLLLLLSGGLGGVQAQRPQQQRQSQAHQQRGLFPAVLNLASNALITTNATCGEKGPEM 65
Query: 49 FCKLVEHVPGRPVRNPQCRICDGNSANPRERHPISHAIDGTNNWWQSPSIQNGREYHWVT 108
+CKLVEHVPG+PVRNPQCRIC+ NS+NP +RHPI++AIDG N WWQSPSI+NG EYH+VT
Sbjct: 66 YCKLVEHVPGQPVRNPQCRICNQNSSNPNQRHPITNAIDGKNTWWQSPSIKNGIEYHYVT 125
Query: 109 ITLDLRQVFQVAYVIIKAANAPRPGNWILERSLDGTTFSPWQYYAVSDSECLSRYNITPR 168
ITLDL+QVFQ+AYVI+KAAN+PRPGNWILERSLD + PWQY+AV+D+ECL+ YNI PR
Sbjct: 126 ITLDLQQVFQIAYVIVKAANSPRPGNWILERSLDDVEYKPWQYHAVTDTECLTLYNIYPR 185
Query: 169 RGPPTYRADDEVICTSYYSRLVPLEHGEIHTSLINGRPSADDLSPKLLEFTSARYIRLRL 228
GPP+Y DDEVICTS+YS++ PLE+GEIH SLINGRPSADD SP+LLEFTSARYIRLR
Sbjct: 186 TGPPSYAKDDEVICTSFYSKIHPLENGEIHISLINGRPSADDPSPELLEFTSARYIRLRF 245
Query: 229 QRIRTLNADLMTLSHREPKELDPIVTRRYYYSIKDISVGGMCICYGHASSCPWDETTKKL 288
QRIRTLNADLM +H++P+E+DPIVTRRYYYS+KDISVGGMCICYGHA +CP D T K
Sbjct: 246 QRIRTLNADLMMFAHKDPREIDPIVTRRYYYSVKDISVGGMCICYGHARACPLDPATNKS 305
Query: 289 QCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKS 348
+C+CEHNTCG+SC++CCPG+HQ+PWR GT + CEACNCH KA++CYYDE+VA++ S
Sbjct: 306 RCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLS 365
Query: 349 LNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSV 408
LN G++ GGGVCINC QNT GINCETC DG++RP VSP PC+PC+CDP+GSL+ V
Sbjct: 366 LNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEV 425
Query: 409 CIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYPTCVSCGCNPVGSASDEPCT 468
C+KD+ H+ G PG C CK G+ G CDRC GY YP C +C C+ +GS +++PC
Sbjct: 426 CVKDEKHA--RRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKNEDPCF 483
Query: 469 GPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFCFGVSDVCSSLSWPVGQVNSMSGW 528
GPC+CKENVEG C RCK GF+NL+E N +GC ECFC GVS+ C S W G++ MSGW
Sbjct: 484 GPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCSGVSNRCQSSYWTYGKIQDMSGW 543
Query: 529 LVTDLISPRKIPSQQDALGGRHQVSINNTAVMQRLAPKYYWAAPEAYLGNKLTAFGGFLK 588
+TDL ++ QQD L Q+SI+N Q L YYW+AP YLGNKL A GG L
Sbjct: 544 YLTDLPGRIRVAPQQDDLDSPQQISISNAEARQALPHSYYWSAPAPYLGNKLPAVGGQLT 603
Query: 589 YTVSYDIPVETVDSNLMSHADVIIKGNGLTLSTQAEGLSLQPYEEYLNVVRLVPENFQDF 648
+T+SYD+ E D+ + +I++GN L++ST + + L P EE+ NV+ L E+F
Sbjct: 604 FTISYDLEEEEEDTERVLQLMIILEGNDLSISTAQDEVYLHPSEEHTNVLLLKEESFTIH 663
Query: 649 HSKRQIDRDQLMTVLANVTHLLIRANYNSAKMALYRLESVSLDIASSNAIDLVVAADVEH 708
+ + R + MTVLAN+ +L++ Y+ A++RL SV+L+ A S D +AA VE
Sbjct: 664 GTHFPVRRKEFMTVLANLKRVLLQITYSFGMDAIFRLSSVNLESAVSYPTDGSIAAAVEV 723
Query: 709 CECPQGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAAEC-NVHGVCIACAHNTTGV 767
C+CP GYTG+SCESC + RV+G +FGGIC+PC+C GHA C +V G C+ C +T G
Sbjct: 724 CQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLNCKDHTGGP 783
Query: 768 HCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYSGAW 827
+C++CLPGFYGEP++GT DCQPCACPL I SNNFSPTCHL+ ++CD C GY+G
Sbjct: 784 YCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPR 843
Query: 828 CERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCAD 887
CERCA+GY+G P+VPG SC PC C+ N+D S G CDS++G CL C T G +CE CAD
Sbjct: 844 CERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCAD 903
Query: 888 GFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLDSGHG 947
G++GDAV AKNC+ C C+ GS S VCH +TG C+C+ NV GQ+CD+C G +GL S G
Sbjct: 904 GYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARG 963
Query: 948 CRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCDRCAHGFYAYQDGSCTPCDCPHTQNTC 1007
C PCNC+ GS S C + GQC C PGV GK+CDRCAHG++ +Q+G CT C+C H N C
Sbjct: 964 CVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNNC 1023
Query: 1008 DPETGECVCPPHTQGVKCEECEDGHWGYDAEVGCQACNCSLVGSTHHRCDVVTGHCQCKS 1067
DP+TG C+CPP+T G KC +C WG+ GC+ACNCS VGS +C+V TG C C
Sbjct: 1024 DPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCNCHP 1083
Query: 1068 KFGGRACDQCSLGYRDFPDCVPCDCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGP 1127
KF G C +CS G+ ++P C CDC L GT C+ E C C ++TG C CK NV G
Sbjct: 1084 KFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGI 1143
Query: 1128 QCNECREGTFALRADNPLGCSPCFCSGLSHLCSELEDYVRTPVTLGSDQPLLRVVSQSNL 1187
C+ CR G F L A NPLGCS C+C G + CSE + +RT VTL ++Q +L +V ++
Sbjct: 1144 HCDRCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGLIRTWVTLKAEQTILPLVDEALQ 1203
Query: 1188 RGTTEGVYYQAPDFLLDAATVRQHIRAEPFYWRLPQQFQGDQLMAYGGKLKYSVAFYSLD 1247
TT+G+ +Q P+ + +R+ + EPFYW+LP+QF+G +LMAYGGKLKY++ F + +
Sbjct: 1204 HTTTKGIVFQHPEIVAHMDLMREDLHLEPFYWKLPEQFEGKKLMAYGGKLKYAIYFEARE 1263
Query: 1248 GVGTSNFEPQVLIKGGR-IRKQVIYMDAPAPENGVRQEQEVAMRENFWKYFNSVS--EKP 1304
G S + PQV+I+GG ++I AP G E+ M E WKY+ +
Sbjct: 1264 ETGFSTYNPQVIIRGGTPTHARIIVRHMAAPLIGQLTRHEIEMTEKEWKYYGDDPRVHRT 1323
Query: 1305 VTREDFMSVLSDIEYILIKASYGQGLQQSRISDISMEV---GRKAEKLHPEEEVASLLEN 1361
VTREDF+ +L DI YILIKA+YG ++QSRIS+ISMEV GR P A L+E
Sbjct: 1324 VTREDFLDILYDIHYILIKATYGNFMRQSRISEISMEVAEQGRGTTMTPP----ADLIEK 1379
Query: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKCLN 1421
C CP G G SC+ C PG++R + G R P P + CVPC CN HS CDP T C N
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGG-RTPGPTLGTCVPCQCNGHSSLCDPETSICQN 1438
Query: 1422 CGDNTAGDHCDVCTSGYYGKVTGSASDCALCACP-HSPPASFSPTCVLEGDHDFRCDACL 1480
C +TAGD C+ C GYYG V G +DC CACP S +FSP+CV EG D+RC AC
Sbjct: 1439 CQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACP 1498
Query: 1481 LGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLRCD 1540
GYEG++CERC+ Y G+P PGGSCQ+C+C+P+GS+ CD +G C CR GA+G +CD
Sbjct: 1499 RGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCD 1558
Query: 1541 ECEPRHILMETDCVSCDDECVGVLLNDLDEIGDAVLSLNLTGIIPVPYGILSNLENTTKY 1600
C+ H +CV C DEC G+LL DL + V+S+NLTG +P PY +L LEN T+
Sbjct: 1559 GCKHWHAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKMLYGLENMTQE 1618
Query: 1601 LQESLLKENMQK---DLGKIKLEGVAEETDNLQKKLTRMLASTQKVNRATERIFKESQDL 1657
L+ L + + L + L + E + L + T++ A ++ + ER ++ L
Sbjct: 1619 LKHLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSL 1678
Query: 1658 AIAIERLQMSITEIMEKT-TLNQTL---DEDFLLPNSTLQNMQQNGTSLLEIMQIRDFTQ 1713
I+ L + EK LN+TL DE F L+ +Q+ +++ ++ ++
Sbjct: 1679 GEFIKELARDAEAVNEKAIKLNETLGTRDEAF---ERNLEGLQKEIDQMIKELRRKNLET 1735
Query: 1714 LHQNATLELKAAEDLLSQIQENYQKPLEELEVLKEAASHVLSKHNNELKAAEALVREAEA 1773
+ A EL AAE LL ++++ + + E E +++ L+ + N++ A L+REA
Sbjct: 1736 QKEIAEDELVAAEALLKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWDLLREATD 1795
Query: 1774 KMQESNHLLLMVNANLREFSDKKLHVQEEQNLTSELIVQGRGLIDAAAAQTDAVQDALEH 1833
K++E+N L + N+ KK V+ + + +G ++D A D + +++
Sbjct: 1796 KIREANRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLADEINSIIDY 1855
Query: 1834 LEDHQDKLLLWSAKIRHHIDDLVMHMSQRNAVDLVYRAEDHAAEFQRLADVLYSGLENIR 1893
+ED Q KL S ++ IDDL + R + V +AE HAA+ + VL L+ +
Sbjct: 1856 VEDIQTKLPPMSEELNDKIDDLSQEIKDRKLAEKVSQAESHAAQLNDSSAVLDGILDEAK 1915
Query: 1894 NVSLNATSAAYVHYNIQSLIEESEELARDAHRTVTETSLLSES----LVSNGKAAVQRSS 1949
N+S NAT+A + NI+ I+E+E++A++A E + L+ L + K +Q+S
Sbjct: 1916 NISFNATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDAKGCLQKSF 1975
Query: 1950 RFLKEGNNLSRKLPGIALELSELRNKTNRFQENAVEITRQTNESLLILRAIPKGIRDKGA 2009
R L E L+ + L+ L+ + ++ R N++L L AIP K
Sbjct: 1976 RILNEAKKLANDVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIPNDTAAKLQ 2035
Query: 2010 KTKELATSASQSAVSTLRDVAGLSQELLNTSASLSRVNTTLRETHQLLQDSTMATLL--A 2067
K+ A A+ +A L + L Q L + +++ ++ +T+ +++D + ++ A
Sbjct: 2036 AVKDKARQANDTAKDVLAQITELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNKIIADA 2095
Query: 2068 GRKVKDVEIQANLLFDRLKPLKMLEENLSRNLSEIKLLISQARKQAASIKVAVSADRDCI 2127
VK++E +A+ L D+LKP+K LE+NL +N+SEIK LI+QARKQA SIKV+VS+ DCI
Sbjct: 2096 DATVKNLEQEADRLIDKLKPIKELEDNLKKNISEIKELINQARKQANSIKVSVSSGGDCI 2155
Query: 2128 RAYQPQISSTNYNTLTLNVKTQEPDNLLFYLGSSTASDFLAVEMRRGRVAFLWDLGSGST 2187
R Y+P+I +YN + +NVKT DNLLFYLGS+ DFLA+EMR+G+V+FLWD+GSG
Sbjct: 2156 RTYKPEIKKGSYNNIVVNVKTAVADNLLFYLGSAKFIDFLAIEMRKGKVSFLWDVGSGVG 2215
Query: 2188 RLEFPDFPIDDNRWHSIHVARFGNIGSLSVKEMSSNQKS---PTKTSKSPGTANVLDVNN 2244
R+E+PD IDD+ W+ I +R G G++SV+ + + S T S SP +LDV+
Sbjct: 2216 RVEYPDLTIDDSYWYRIVASRTGRNGTISVRALDGPKASIVPSTHHSTSPPGYTILDVDA 2275
Query: 2245 STLMFVGGLGGQIKKSPAVKVTHFKGCLGEAFLNGKSIGLWNYIEREGKCRGCFGSSQNE 2304
+ ++FVGGL G++KK+ AV+V F GC+GE + + K IGLWN+ E+EG C+GC S Q E
Sbjct: 2276 NAMLFVGGLTGKLKKADAVRVITFTGCMGETYFDNKPIGLWNFREKEGDCKGCTVSPQVE 2335
Query: 2305 DP--SFHFDGSGYSVVEKSLP--ATVTQIIMLFNTFSPNGLLLYLGSYGTKDFLSIELFR 2360
D + FDG GY++V + + ++ ++ F TFS + LL+YL + +DF+S+EL
Sbjct: 2336 DSEGTIQFDGEGYALVSRPIRWYPNISTVMFKFRTFSSSALLMYLATRDLRDFMSVELTD 2395
Query: 2361 GRVKVMTDLGSGPITLLTDRRYNNGTWYKIAFQRNRKQGVLAVIDAYNTSNKETKQGETP 2420
G +KV DLGSG ++++++ +N+G W R +KQ ++++D +T+ +E +
Sbjct: 2396 GHIKVSYDLGSGMASVVSNQNHNDGKWKSFTLSRIQKQANISIVD-IDTNQEENIATSSS 2454
Query: 2421 GASSDLNRLDKDPIYVGGLPR----SRVVRRGVTTKSFVGCIKNLEISRSTFDLLRNS-- 2474
G + L+ D IY GGLP S R V K + GC+K++EISR+ +++L +
Sbjct: 2455 GNNFGLDLKADDKIYFGGLPTLRNLSMKARPEVNLKKYSGCLKDIEISRTPYNILSSPDY 2514
Query: 2475 YGVRKGCLLEPIRSVSFLKGGYIELPPKSLSPESEWLVTFATTNSSGIILAALGG-DVEK 2533
GV KGC LE + +VSF K G++EL P + +E ++F+T N SGIIL GG
Sbjct: 2515 VGVTKGCSLENVYTVSFPKPGFVELSPVPIDVGTEINLSFSTKNESGIILLGSGGTPAPP 2574
Query: 2534 RGDREEAHVPFFSVMLIGGNIEVHVNPGDGTGLRKALLHAPTGTCSDGQAHSISLVRNRR 2593
R R + ++ ++L G +EVH++ G T +RK ++ DG+ HS+ + R R
Sbjct: 2575 RRKRRQTGQAYYVILLNRGRLEVHLSTGART-MRKIVIRPEPNLFHDGREHSVHVERTRG 2633
Query: 2594 IITVQLDENNPVEMKLGTLVESRTINVSNLYVGGIPEGEGTSLLTMRRSFHGCIKNLIFN 2653
I TVQ+DEN + L + I V L+VGG P S L F GCI NL+ N
Sbjct: 2634 IFTVQVDEN---RRYMQNLTVEQPIEVKKLFVGGAPPEFQPSPLRNIPPFEGCIWNLVIN 2690
Query: 2654 LELLDFNSAVGHEQVDLDTCWLSERPKLAPDAEDSK-----LLPEP---RAFPE------ 2699
+DF V + D+ C KL D + + + PEP AFP
Sbjct: 2691 SVPMDFARPVSFKNADIGRC---AHQKLREDEDGAAPAEIVIQPEPVPTPAFPTPTPVLT 2747
Query: 2700 --QCVVDAALEYVPGAHQFGLTQNSHFILPFNQSAVRKKLSVELSIRTFASSGLIYYMAH 2757
C ++ + G+ QFGL++NSH + F+ + V+ +L++EL +RT A SGL++YMA
Sbjct: 2748 HGPCAAESEPALLIGSKQFGLSRNSHIAIAFDDTKVKNRLTIELEVRTEAESGLLFYMAR 2807
Query: 2758 QNQADYAVLQLHGGRLHFMFDLGKGRTKVSHPALLSDGKWHTVKTDYVKRKGFITVDGRE 2817
N AD+A +QL G +F +DLG G T P ++DG+WH +K K++G + VDG
Sbjct: 2808 INHADFATVQLRNGLPYFSYDLGSGDTHTMIPTKINDGQWHKIKIMRSKQEGILYVDGAS 2867
Query: 2818 SPMVTVVGDGTMLDVEGLFYLGGLPSQYQARKIGNITHSIPACIGDVTVNSKQLDKDSPV 2877
+ ++ +LDV G+ Y+GGLP Y R+IG +T+SI C+ ++ + D + P
Sbjct: 2868 NRTIS-PKKADILDVVGMLYVGGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPT 2926
Query: 2878 SAFTVNRCYAVAQEGTYFDGSGYAALVKEGYKVQSDVNITLEFRTSSQNGVLLGISTAKV 2937
S+F V C+A AQ GTYFDG+G+A V G+KV D+ + EFRT++ GVLLGIS+ K+
Sbjct: 2927 SSFHVGTCFANAQRGTYFDGTGFAKAV-GGFKVGLDLLVEFEFRTTTTTGVLLGISSQKM 2985
Query: 2938 DAIGLELVDGKVLFHVNNGAGRITAAYEPKTATVLCDGKWHTLQANKSKHRITLIVDGNA 2997
D +G+E++D K++FHV+NGAGR TA Y+ LCDG+WH + ANK KHRI L VDGN
Sbjct: 2986 DGMGIEMIDEKLMFHVDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIKHRIELTVDGNQ 3045
Query: 2998 VGAESPHTQSTSVDTNNPIYVGGYPAGVKQKCLRSQTSFRGCLRKLALIK-SPQVQSFDF 3056
V A+SP+ STS DTN+P++VGG+P +KQ L + FRGC+R L L K + + +F
Sbjct: 3046 VEAQSPNPASTSADTNDPVFVGGFPDDLKQFGLTTSIPFRGCIRSLKLTKGTGKPLEVNF 3105
Query: 3057 SRAFELHGVFLHSCP 3071
++A EL GV SCP
Sbjct: 3106 AKALELRGVQPVSCP 3120
>gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens]
Length = 3333
Score = 631 bits (1627), Expect = e-180
Identities = 588/2236 (26%), Positives = 956/2236 (42%), Gaps = 277/2236 (12%)
Query: 947 GCRPCNCSVAGSVSDGCTDEG-QCHCVPGVAGKRCDRCAHGFYAYQDGSCTPCDCPHTQN 1005
G PC C G+ C+ EG QC C P V G++C RCA G Y + C PC C +
Sbjct: 1262 GALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFP--RCKPCSCG--RR 1317
Query: 1006 TCDPETGECVCPPHTQGVKCEECEDGHWGYDAEVGCQACNCSLVGSTHH---RCDVVTGH 1062
C+ TG+C CPP T +CE CE + + GC+ CNCS G+ CD +G
Sbjct: 1318 LCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQ 1377
Query: 1063 CQCKSKFGGRACDQCSLGYRDFPDCVPCDCDLRGTSGDACNLEQGLCGCVEETGACPCKE 1122
C+CK + GR CD+C+ G+ FP+CVPC+C+ GT E G+C TGAC CKE
Sbjct: 1378 CRCKPRITGRQCDRCASGFYRFPECVPCNCNRDGT-------EPGVCD--PGTGACLCKE 1428
Query: 1123 NVFGPQCNECREGTFALRADNPLGCSPCFCSGLSHLCS-----------------ELEDY 1165
NV G +CN CREG+F L N GC+ CFC G+++ C E D
Sbjct: 1429 NVEGTECNVCREGSFHLDPANLKGCTSCFCFGVNNQCHSSHKRRTKFVDMLGWHLETADR 1488
Query: 1166 VRTPVTLGSDQPLLRVVSQSNLRGTTEGVYYQAPDFLLDAATVRQHIRAEPFYWRLPQQF 1225
V PV+ + V L T W P +
Sbjct: 1489 VDIPVSFNPGSNSM-VADLQELPATIHSAS-----------------------WVAPTSY 1524
Query: 1226 QGDQLMAYGGKLKYSVAFYSLDG-VGTSNFEPQVLIKGGRIRKQVIYMDAPAPENGVRQE 1284
GD++ +YGG L Y + L G + +P V + G + +IY + P
Sbjct: 1525 LGDKVSSYGGYLTYQAKSFGLPGDMVLLEKKPDVQLTGQHM--SIIYEETNTPRPDRLHH 1582
Query: 1285 QEVAMRENFWKYFNSVSEKPVTREDFMSVLSDIEYILIKASYGQGLQQSRISDISMEVGR 1344
V + E +++ +S PV+RE+ M+VLS + + I+ Y Q+ +S++ +E
Sbjct: 1583 GRVHVVEGNFRHASS--RAPVSREELMTVLSRLADVRIQGLYFTETQRLTLSEVGLEEAS 1640
Query: 1345 KAEKLHPEEEVASLLENCVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCS 1404
+A +E C CPP G SCQ C+PGY+R + R CVPC+
Sbjct: 1641 DTGS----GRIALAVEICACPPAYAGDSCQGCSPGYYRDHKGLYTGR--------CVPCN 1688
Query: 1405 CNNHSDTCDPNTGKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSP 1464
CN HS+ C +G C+NC NTAG+HC+ C GYYG + C C CPH+ SF+
Sbjct: 1689 CNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGS--CRACPCPHTN--SFAT 1744
Query: 1465 TCVLEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRT 1524
CV+ G D RC +C GY G CERC+ Y+GNPQ GGSCQ C CN +G + G C
Sbjct: 1745 GCVVNGG-DVRC-SCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQL-GSCHPL 1801
Query: 1525 SGQCVCRLGASGLRCDECEPRHILMETDCVSCDDECVGVLLNDLDEIGDAV--LSLNLTG 1582
+G C+ + +EC+ DC D CV LLNDL +G+ + + L G
Sbjct: 1802 TGDCINQEPKDSSPAEECD--------DC----DSCVMTLLNDLATMGEQLRLVKSQLQG 1849
Query: 1583 IIPVPYGILS---NLENTTKYLQESLLKENMQKDLGKIKLEGVA-------EETDNLQKK 1632
+ G+L ++E K L+ LL K+EG+ +E + LQ+K
Sbjct: 1850 L-SASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDLNQEFETLQEK 1908
Query: 1633 LTRMLASTQKVNRATERIFKESQDLAIAIERLQMSITEIMEKTTLNQTLDEDFLLPNSTL 1692
Q +N R + +++L + I+ + ++ ++++ ++ T E +P+
Sbjct: 1909 AQVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVHILLKQ--ISGTDGEGNNVPSGDF 1966
Query: 1693 QNMQQNGTSLLEIMQIRDFTQLHQNATLELKAAEDLLSQIQENYQKPLEELEVLKEAASH 1752
++ ++ R+F + + A + + ++ LL++I+ + E L +
Sbjct: 1967 SREWAEAQRMMRELRNRNFGKHLREAEADKRESQLLLNRIRTWQKTHQGENNGLANSIRD 2026
Query: 1753 VLSKHNNELKAAEALVREAEAKMQESNHLLLMVNANLREFSDKKLHVQEEQNLTSELIVQ 1812
L+++ +L A ++EA A+ +++N L N R + V+E +L S+ +
Sbjct: 2027 SLNEYEAKLSDLRARLQEAAAQAKQANGLN---QENERALGAIQRQVKEINSLQSDF-TK 2082
Query: 1813 GRGLIDAAAAQTDAVQDALEHLEDHQDKLLLWSAKIRHHIDDLVMHMSQR-NAVDLVYRA 1871
D++ QT+ +E + +KL + R + D V +S+ LV A
Sbjct: 2083 YLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRELSRSAGKTSLVEEA 2142
Query: 1872 EDHAAEFQRLADVLYSGLENIRNVSLN--ATSAAYVHYNIQSLIEESEELARDAHRTVTE 1929
E HA Q LA L N L A AA + NI + I+ +E+ A A + +E
Sbjct: 2143 EKHARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIKAAEDAANRA-ASASE 2201
Query: 1930 TSL---LSESLVSNGKAAVQRSSRFLKEGNNLSRKLPGIALELSELRNKTNRFQENAVEI 1986
++L + E L K S + L E +KL E+ N Q+ +
Sbjct: 2202 SALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLK------QEVSPALNNLQQTLNIV 2255
Query: 1987 TRQTNESLLILRAIPKGIRDKGAKTKELATSASQSAVSTLRDVAGLSQELLNT-SASLSR 2045
T Q L + G+ + S+++S V D+ + LN + R
Sbjct: 2256 TVQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVER 2315
Query: 2046 VNTTLRETH-----QLLQDSTMATLLAGRKVKDVEIQANLLFDRLKPLKMLEENLSRNLS 2100
+ T T + L D+ + K+ D+ + + +L PL N+S N+
Sbjct: 2316 IKDTYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPLG----NISDNMD 2371
Query: 2101 EIKLLISQARKQAASIKVAVSAD-RDCIRAYQPQISSTNYNTLTLNVKTQEPDN------ 2153
I+ LI QAR A+ + V + + + + P +L++ Q P++
Sbjct: 2372 RIRELIQQARDAASKVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQRPNSRENGGT 2431
Query: 2154 ---LLFYLGSSTAS-DFLAVEMRRGRVAFLWDLGSGSTRLEFPDFPIDDNRWHSIHVARF 2209
+ YLG+ AS D++ + + G++ +++LG L+ ++
Sbjct: 2432 ENMFVMYLGNKDASRDYIGMAVVDGQLTCVYNLGDREAELQVDQILTKSETKEAV----M 2487
Query: 2210 GNIGSLSVKEMSSNQKSPTKTSKSPGTANVLDV---NNSTLM---------FVGGLGGQI 2257
+ + + + + TS P T V D+ N++TL+ +VGG
Sbjct: 2488 DRVKFQRIYQFARLNYTKGATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGYPPDF 2547
Query: 2258 KKSPAVKVTHFKGCLGEAFLNGKSIGLWNYIE----REGKCRGCFGSSQNEDPSFHFDGS 2313
K + +KGC+ LN + L+N+ + + C + D ++ F+G+
Sbjct: 2548 KLPSRLSFPPYKGCIELDDLNENVLSLYNFKKTFNLNTTEVEPCRRRKEESDKNY-FEGT 2606
Query: 2314 GYSVVEKSLPATVTQIIMLFNTFSPNGLLLYLGSYGTKDFLSIELFRGRVKVMTDLGSG- 2372
GY+ V A + T GLL + + G + F+S+ + G++ V L S
Sbjct: 2607 GYARVPTQPHAPIPTFGQTIQTTVDRGLLFFAEN-GDR-FISLNIEDGKLMVRYKLNSEL 2664
Query: 2373 PITLLTDRRYNNGTWYKIAFQRNRKQGVLAV-IDAYNTSNKETKQGETPGASSDLNRLDK 2431
P NNG + I + + Q + + +D NT GE D
Sbjct: 2665 PKERGVGDAINNGRDHSIQIKIGKLQKRMWINVDVQNT----IIDGEV---------FDF 2711
Query: 2432 DPIYVGGLPRSRVVRRGVTTKSFVGCIKNLEISRSTFDLLRNSYGVRKGCLLE--PIRSV 2489
Y+GG+P + R ++T +F GC+KNL+ S L ++ GV K C + +RS
Sbjct: 2712 STYYLGGIPIAIRERFNISTPAFRGCMKNLK-KTSGVVRLNDTVGVTKKCSEDWKLVRSA 2770
Query: 2490 SFLKGGYIELPPKSLSPESEWLVTFA--TTNSSGIILAALGGDVEKRGDREEAHVPFFSV 2547
SF +GG + L P +F T SGI+L + V
Sbjct: 2771 SFSRGGQLSFTDLGLPPTDHLQASFGFQTFQPSGILLD------------HQTWTRNLQV 2818
Query: 2548 MLIGGNIEVHVNPGDGTGLRKALLHAPTGTCSDGQAHSISLVRN----RRIITVQLDENN 2603
L G IE+ + G+ + K+ T DG H +S++ + R +I QL N+
Sbjct: 2819 TLEDGYIELSTSDS-GSPIFKS-----PQTYMDGLLHYVSVISDNSGLRLLIDDQLLRNS 2872
Query: 2604 PVEMKLGTLVESRTINVSNLYVGGIPEGEGTSLLTMRRSFHGCIKN-----LIFNLELLD 2658
+L + SR +L +GG +F GCI N L + E+LD
Sbjct: 2873 K---RLKHISSSR----QSLRLGG-------------SNFEGCISNVFVQRLSLSPEVLD 2912
Query: 2659 FNSAVGHEQVDLDTCWLSERPKL-----------APDAEDSKLLPE-PRAFPEQCVV-DA 2705
S V L C L++ P L ++LL + P A P V
Sbjct: 2913 LTSNSLKRDVSLGGCSLNKPPFLMLLKGSTRFNKTKTFRINQLLQDTPVASPRSVKVWQD 2972
Query: 2706 ALEYVP------GAHQFGLTQNSHFILPFNQSAVRKKLSVELSIRTFASSGLIYYMAHQN 2759
A +P GA QFG SH + Q ++ + + ++T +S GL+++ +N
Sbjct: 2973 ACSPLPKTQANHGALQFGDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLVFHTGTKN 3032
Query: 2760 QADYAVLQLHGGRLHFMFDLGKGRTKVSHPALLSDGKWHTVKTDYVKRKGFITVDGRESP 2819
+ L L GRL F + ++ +DGKWHTV + KG + VDG +
Sbjct: 3033 S--FMALYLSKGRLVFALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRAR 3090
Query: 2820 MVTVVGDGTMLDVEGLFYLGGLPSQYQARKIGNITHSIPACIGDVTVNSKQLDKDSPVSA 2879
++ G+ T + + YLG PS + T+S C+ + ++SK L +P S+
Sbjct: 3091 EGSLPGNST-ISIRAPVYLGSPPS---GKPKSLPTNSFVGCLKNFQLDSKPL--YTPSSS 3144
Query: 2880 FTVNRCY-AVAQEGTYFDGSGYAALVKEGYKVQSDVNITLEFRTSSQNGVLLGISTAKVD 2938
F V+ C ++G YF G ++ + + + R S G+L+ I +
Sbjct: 3145 FGVSSCLGGPLEKGIYFSEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGK 3204
Query: 2939 AIGLELVDGKVLFHVNNGAGRITAAYEPKTATVLCDGKWHTLQANKSKH--RITLIVDGN 2996
+ + L GKV +++GAG + + PK + LCDG+WH++ +H + L D +
Sbjct: 3205 HLCVYLEAGKVTASMDSGAGGTSTSVTPKQS--LCDGQWHSVAVTIKQHILHLELDTDSS 3262
Query: 2997 AVGAESPHTQSTSVDTNNPIYVGGYPAGVKQKCLRSQTSFRGCLRKLALIKSPQVQSFDF 3056
+ P ++ T P+++GG PA + + SF GCLR + + P
Sbjct: 3263 YTAGQIPFPPAS---TQEPLHLGGAPANLTTLRIPVWKSFFGCLRNIHVNHIP----VPV 3315
Query: 3057 SRAFELHG-VFLHSCP 3071
+ A E+ G V L+ CP
Sbjct: 3316 TEALEVQGPVSLNGCP 3331
Score = 456 bits (1172), Expect = e-127
Identities = 242/569 (42%), Positives = 318/569 (55%), Gaps = 76/569 (13%)
Query: 6 LLVLLLCVAAQC----RQRG------LFPAILNLASNAHISTNATCGEKGP-------EM 48
LL+L+L V C R G L P NLA A I ATCGE+GP E+
Sbjct: 21 LLLLVLRVLPACGATARDPGAAAGLSLHPTYFNLAEAARIWATATCGERGPGEGRPQPEL 80
Query: 49 FCKLVEHVP----GRPVRNPQCRICDGNSANPRERHPISHAIDGTNNWWQSPSIQNGREY 104
+CKLV G ++ C C NS +PR+ HP+++AIDG+ WWQSP + +G +Y
Sbjct: 81 YCKLVGGPTAPGSGHTIQGQFCDYC--NSEDPRKAHPVTNAIDGSERWWQSPPLSSGTQY 138
Query: 105 HWVTITLDLRQVFQVAYVIIKAANAPRPGNWILERSLD-GTTFSPWQYYAVSDSECLSRY 163
+ V +TLDL Q+F VAY++IK AN+PRP W+LERS+D G+T+SPWQY+A S +CL +
Sbjct: 139 NRVNLTLDLGQLFHVAYILIKFANSPRPDLWVLERSVDFGSTYSPWQYFAHSKVDCLKEF 198
Query: 164 NITPRRGPPTYRADDEVICTSYYSRLVPLEHGEIHTSLINGRPSADDL--SPKLLEFTSA 221
R DD+V+C + YSR+VPLE+GE+ SLINGRP A + S L EFT A
Sbjct: 199 G---REANMAVTRDDDVLCVTEYSRIVPLENGEVVVSLINGRPGAKNFTFSHTLREFTKA 255
Query: 222 RYIRLRLQRIRTLNADLMTLSHREPKELDPIVTRRYYYSIKDISVGGMCICYGHASSCPW 281
IRLR R TL L++ + R DP VTRRYYYSIKDIS+GG C+C GHA C
Sbjct: 256 TNIRLRFLRTNTLLGHLISKAQR-----DPTVTRRYYYSIKDISIGGQCVCNGHAEVCNI 310
Query: 282 DETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDES 341
+ K +C+C+H+TCGE+C+RCC GY+Q+ WRP + CEACNCH A +CYYD
Sbjct: 311 NNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPD 370
Query: 342 VAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDP 401
V +Q+ SLNT G + GGGVCINC NT G+NCE C GYYRP+ V + C PC+CDP
Sbjct: 371 VERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDP 430
Query: 402 VGSLSSVCIKDDLHSD-LHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYPTCVSCGCNPVG 460
H+D G G+C CK + G+ C++C +GY ++P C+ PV
Sbjct: 431 E------------HADGCEQGS--GRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVS 476
Query: 461 SASDE----------------------PCTGPCVCKENVEGKACDRCKPGFYNLKEKNPR 498
+ S E G C+C+ VEG CD C+ GFY+
Sbjct: 477 TPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFPI---- 532
Query: 499 GCSECFCFGVSDVCSSLSWPVGQVNSMSG 527
C C+C + S GQ G
Sbjct: 533 -CQACWCSALGSYQMPCSSVTGQCECRPG 560
Score = 330 bits (847), Expect = 1e-89
Identities = 204/606 (33%), Positives = 292/606 (48%), Gaps = 75/606 (12%)
Query: 289 QCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKS 348
QC C+ N G C RC G++ P C+ C+C + +
Sbjct: 1284 QCPCQPNVIGRQCTRCATGHYGFP----------RCKPCSCGRRLCE------------- 1320
Query: 349 LNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSV 408
GQ R C T+ CE C H S + C CNC G++ +
Sbjct: 1321 -EMTGQCR-------CPPRTVRPQCEVC-----ETHSFSFHPMAGCEGCNCSRRGTIEAA 1367
Query: 409 CIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYPTCVSCGCNPVGSASD--EP 466
+ D S GQC CK TG +CDRC G+ +P CV C CN G+ +P
Sbjct: 1368 MPECDRDS--------GQCRCKPRITGRQCDRCASGFYRFPECVPCNCNRDGTEPGVCDP 1419
Query: 467 CTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFCFGVSDVCSSLSWPVGQVNSMS 526
TG C+CKENVEG C+ C+ G ++L N +GC+ CFCFGV++ C S + M
Sbjct: 1420 GTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFCFGVNNQCHSSHKRRTKFVDML 1479
Query: 527 GWLVTDLISPRKIPSQQDALGGRHQVSINNTAVMQRLAPKYY---WAAPEAYLGNKLTAF 583
GW + + + D + S + A +Q L + W AP +YLG+K++++
Sbjct: 1480 GWHL-------ETADRVDIPVSFNPGSNSMVADLQELPATIHSASWVAPTSYLGDKVSSY 1532
Query: 584 GGFLKYTV-SYDIPVETVDSNLMSHADVIIKGNGLTLSTQAEGLSLQPYEEYLNVVRLVP 642
GG+L Y S+ +P + V L DV + G +++ + E + +P + V +V
Sbjct: 1533 GGYLTYQAKSFGLPGDMV--LLEKKPDVQLTGQHMSIIYE-ETNTPRPDRLHHGRVHVVE 1589
Query: 643 ENFQDFHSKRQIDRDQLMTVLANVTHLLIRANYNSAKMALYRLESVSLDIASSNAIDLVV 702
NF+ S+ + R++LMTVL+ + + I+ Y + L L V L+ AS +
Sbjct: 1590 GNFRHASSRAPVSREELMTVLSRLADVRIQGLYFTETQRL-TLSEVGLEEASDTGSGRIA 1648
Query: 703 AADVEHCECPQGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAAEC-NVHGVCIACA 761
A VE C CP Y G SC+ C GYYR L+ G C PC C+GH+ +C + G+C+ C
Sbjct: 1649 LA-VEICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQ 1707
Query: 762 HNTTGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAP 821
HNT G HCE+C G+YG G C+ C CP T N+F+ C +N GD V C C
Sbjct: 1708 HNTAGEHCERCQEGYYG---NAVHGSCRACPCPHT---NSFATGCVVNGGD-VRCS-CKA 1759
Query: 822 GYSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAH 881
GY+G CERCA GY+GNP G SC PC C+ N + G C +TG+C+ D +
Sbjct: 1760 GYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSN---GQLGSCHPLTGDCIN-QEPKDSSP 1815
Query: 882 CERCAD 887
E C D
Sbjct: 1816 AEECDD 1821
Score = 227 bits (579), Expect = 1e-58
Identities = 142/454 (31%), Positives = 193/454 (42%), Gaps = 77/454 (16%)
Query: 727 YYRVDGILFGGICQPCECHGHAAECNVHG----VCIACAHNTTGVHCEQCLPGFYGEPSR 782
YY + I GG C C+GHA CN++ C H+T G C++C G+ R
Sbjct: 287 YYSIKDISIGG---QCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGY--NQRR 341
Query: 783 GTPG------DCQPCACPLTIASNNFSPTCHLNDGD---------EVVCDWCAPGYSGAW 827
P +C+ C C ++ + P VC C +G
Sbjct: 342 WRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVN 401
Query: 828 CERCADGYY---GNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCER 884
CE+CA GYY G P + C+PC C DP A C+ +G C C N G +CE+
Sbjct: 402 CEQCAKGYYRPYGVPVDAPDGCIPCSC----DPEHADGCEQGSGRC-HCKPNFHGDNCEK 456
Query: 885 CADGFYG-----------------DAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNV 927
CA G+Y + A + + C+C+++G +C G C C+P V
Sbjct: 457 CAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAH-GRCLCRPGV 515
Query: 928 TGQQCDQCLHGYYGLDSGHGCRPCNCSVAGSVSDGCTD-EGQCHCVPGVAGKRCDRCAHG 986
G +CD C G+Y C+ C CS GS C+ GQC C PGV G+RCDRC G
Sbjct: 516 EGPRCDTCRSGFYSFPI---CQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSG 572
Query: 987 FYAYQ--DGSCTPCDCPHTQNTCDPETGECVCPPHTQGVKCEECEDGHWGYDAE--VGCQ 1042
Y + GS + CD T N+ G C C H +G C C+ +W D E GC
Sbjct: 573 AYDFPHCQGSSSACDPAGTINS---NLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCS 629
Query: 1043 ACNCSLVGSTHH--RCDVVTGHCQCKSKFGGRACDQCSLGY-----RDFPDCVPCDCDLR 1095
C C G+ C G C CKS GG +CD C GY ++ C C CD+
Sbjct: 630 ECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIG 689
Query: 1096 GTSGDACNLEQGLCGCVEETGACPCKENVFGPQC 1129
G C+ +G C C+E+V G C
Sbjct: 690 GALSSMCS---------GPSGVCQCREHVVGKVC 714
Score = 217 bits (552), Expect = 2e-55
Identities = 140/431 (32%), Positives = 182/431 (42%), Gaps = 77/431 (17%)
Query: 709 CECPQGYTGTSCESCLSGY----YRVDGILFGGICQPCECHGHAAECNVH---------- 754
CEC G +C+ C +GY +R C+ C CHGHA+ C
Sbjct: 319 CECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASL 378
Query: 755 ---------GVCIACAHNTTGVHCEQCLPGF---YGEPSRGTPGDCQPCACPLTIAS--N 800
GVCI C HNT GV+CEQC G+ YG P P C PC+C A
Sbjct: 379 NTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPV-DAPDGCIPCSCDPEHADGCE 437
Query: 801 NFSPTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNP-----------TVPGESCVPC 849
S CH C P + G CE+CA GYY P T E V
Sbjct: 438 QGSGRCH-----------CKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAG 486
Query: 850 D---CSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCADGFYGDAVTAKNCRACECHV 906
D C N++ CD+ G CL C +G C+ C GFY + C+AC C
Sbjct: 487 DIKGCDCNLEGVLPEICDA-HGRCL-CRPGVEGPRCDTCRSGFYSFPI----CQACWCSA 540
Query: 907 KGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLDSGHGCRPCNCSVAGSVSDGCTDE 966
GS+ C TG C+C+P VTGQ+CD+CL G Y G C AG+++ ++
Sbjct: 541 LGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSA-CDPAGTIN---SNL 596
Query: 967 GQCHCVPGVAGKRCDRCAHGFY---AYQDGSCTPCDCPHTQNT------CDPETGECVCP 1017
G C C V G C RC ++ C+ C C H T C G+C C
Sbjct: 597 GYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKC-HKAGTVSGTGECRQGDGDCHCK 655
Query: 1018 PHTQGVKCEECEDGHWGYDAE--VGCQACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACD 1075
H G C+ CEDG++ + GCQ C C + G+ C +G CQC+ G+ C
Sbjct: 656 SHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQ 715
Query: 1076 QCSLGYRDFPD 1086
+ Y FPD
Sbjct: 716 RPENNYY-FPD 725
Score = 191 bits (485), Expect = 1e-47
Identities = 128/421 (30%), Positives = 174/421 (41%), Gaps = 73/421 (17%)
Query: 791 CACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNPTVPG-----ES 845
C C N + C++N+ +++ C G C+RC GY P
Sbjct: 299 CVC------NGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHE 352
Query: 846 CVPCDCSGNV-----DPSEAGHCDSVT--------GECLKCLGNTDGAHCERCADGFY-- 890
C C+C G+ DP S+ G C+ C NT G +CE+CA G+Y
Sbjct: 353 CEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRP 412
Query: 891 -GDAVTAKN-CRACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGL------ 942
G V A + C C C + H+ C +G C CKPN G C++C GYY
Sbjct: 413 YGVPVDAPDGCIPCSCDPE--HADGCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRI 470
Query: 943 -----------DSGHG-CRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCDRCAHGFYAY 990
D G + C+C++ G + + C G+C C PGV G RCD C GFY++
Sbjct: 471 PIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSF 530
Query: 991 QDGSCTPCDCPHT---QNTCDPETGECVCPPHTQGVKCEECEDGHWGYDAEVGCQACNCS 1047
C C C Q C TG+C C P G +C+ C G + + G + C
Sbjct: 531 P--ICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSA-CD 587
Query: 1048 LVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGY----RDFPD-CVPCDCDLRGTSGDAC 1102
G+ + G+CQCK G C +C L Y ++ P C C C GT
Sbjct: 588 PAGTINSNL----GYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTG 643
Query: 1103 NLEQGLCGCVEETGACPCKENVFGPQCNECREGTFALRADNPLGCSPCFC---SGLSHLC 1159
QG G C CK +V G C+ C +G FAL N GC C C LS +C
Sbjct: 644 ECRQG-------DGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMC 696
Query: 1160 S 1160
S
Sbjct: 697 S 697
Score = 125 bits (314), Expect = 6e-28
Identities = 67/208 (32%), Positives = 91/208 (43%), Gaps = 22/208 (10%)
Query: 897 KNCRACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLDSGHGCRPCNCSVA 956
K CECH G+ C E G C C+PNV G+QC +C G+YG C+PC+C
Sbjct: 1261 KGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPR---CKPCSC--G 1315
Query: 957 GSVSDGCTDEGQCHCVPGVAGKRCDRC-AHGFYAYQDGSCTPCDCPH------TQNTCDP 1009
+ + T GQC C P +C+ C H F + C C+C CD
Sbjct: 1316 RRLCEEMT--GQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDR 1373
Query: 1010 ETGECVCPPHTQGVKCEECEDGHWGYDAEVGCQACNCSLVGSTHHRCDVVTGHCQCKSKF 1069
++G+C C P G +C+ C G + + C CNC+ G+ CD TG C CK
Sbjct: 1374 DSGQCRCKPRITGRQCDRCASGFYRFPE---CVPCNCNRDGTEPGVCDPGTGACLCKENV 1430
Query: 1070 GGRACDQCSLGY-----RDFPDCVPCDC 1092
G C+ C G + C C C
Sbjct: 1431 EGTECNVCREGSFHLDPANLKGCTSCFC 1458
Score = 121 bits (303), Expect = 1e-26
Identities = 61/161 (37%), Positives = 86/161 (53%), Gaps = 18/161 (11%)
Query: 819 CAPGYSGAWCERCADGYY-GNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNT 877
C P Y+G C+ C+ GYY + + CVPC+C+G+ + C +G C+ C NT
Sbjct: 1656 CPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGH-----SNQCQDGSGICVNCQHNT 1710
Query: 878 DGAHCERCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETG--LCDCKPNVTGQQCDQC 935
G HCERC +G+YG+AV +CRAC C S + C + G C CK TG QC++C
Sbjct: 1711 AGEHCERCQEGYYGNAVHG-SCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERC 1769
Query: 936 LHGYYGLDS--GHGCRPCNCSVAGSVSDGCTDEGQCHCVPG 974
GY+G G C+PC+C+ G + G CH + G
Sbjct: 1770 APGYFGNPQKFGGSCQPCSCNSNGQL-------GSCHPLTG 1803
Score = 115 bits (289), Expect = 5e-25
Identities = 72/195 (36%), Positives = 92/195 (47%), Gaps = 34/195 (17%)
Query: 1364 CPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAP--CVPCSCN-NHSDTCDPNTGKCL 1420
C T G +C+ CA GY+R P G P+ AP C+PCSC+ H+D C+ +G+C
Sbjct: 393 CQHNTAGVNCEQCAKGYYR---PYGV-----PVDAPDGCIPCSCDPEHADGCEQGSGRC- 443
Query: 1421 NCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPT--------CVLEGDH 1472
+C N GD+C+ C GYY + P S P+S P C LEG
Sbjct: 444 HCKPNFHGDNCEKCAIGYYN----FPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVL 499
Query: 1473 DFRCDA-----CLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQ 1527
CDA C G EG C+ C S +Y P CQ C C+ GS C +GQ
Sbjct: 500 PEICDAHGRCLCRPGVEGPRCDTCRSGFYSFP-----ICQACWCSALGSYQMPCSSVTGQ 554
Query: 1528 CVCRLGASGLRCDEC 1542
C CR G +G RCD C
Sbjct: 555 CECRPGVTGQRCDRC 569
Score = 110 bits (276), Expect = 2e-23
Identities = 97/379 (25%), Positives = 137/379 (36%), Gaps = 97/379 (25%)
Query: 662 VLANVTHLLIRANYNSAKMALYRLESVSLDIASSNAIDLVVAADVEH----------CEC 711
V N H N YR V +D + + D EH C C
Sbjct: 389 VCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGC---IPCSCDPEHADGCEQGSGRCHC 445
Query: 712 PQGYTGTSCESCLSGYYRVDGIL---------------FGGICQPCECH--GHAAE-CNV 753
+ G +CE C GYY L G + C+C+ G E C+
Sbjct: 446 KPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDA 505
Query: 754 HGVCIACAHNTTGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDE 813
HG C+ C G C+ C GFY P CQ C C A ++ C G
Sbjct: 506 HGRCL-CRPGVEGPRCDTCRSGFYSFPI------CQACWCS---ALGSYQMPCSSVTGQ- 554
Query: 814 VVCDWCAPGYSGAWCERCADGYYGNPTVPGES--CVP----------CDCSGNVD----- 856
C+ C PG +G C+RC G Y P G S C P C C +V+
Sbjct: 555 --CE-CRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNLGYCQCKLHVEGPTCS 611
Query: 857 -------------PSEAGHCD-------SVTGECLK------CLGNTDGAHCERCADGFY 890
PS C S TGEC + C + G C+ C DG++
Sbjct: 612 RCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYF 671
Query: 891 G-DAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLDSGHGCR 949
+ C+ C+C + G+ S++C +G+C C+ +V G+ C + + YY D H
Sbjct: 672 ALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQRPENNYYFPDLHH--- 728
Query: 950 PCNCSVAGSVSDGCTDEGQ 968
+ + DG T G+
Sbjct: 729 -----MKYEIEDGSTPNGR 742
Score = 107 bits (268), Expect = 1e-22
Identities = 55/161 (34%), Positives = 76/161 (47%), Gaps = 10/161 (6%)
Query: 879 GAHCERCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLC-DCKPNVTGQQCDQCLH 937
G C+ C+ G+Y D R C+ G HS C +G+C +C+ N G+ C++C
Sbjct: 1662 GDSCQGCSPGYYRDHKGLYTGRCVPCNCNG-HSNQCQDGSGICVNCQHNTAGEHCERCQE 1720
Query: 938 GYYGLDSGHGCRPCNCSVAGSVSDGCTDEG---QCHCVPGVAGKRCDRCAHGFYAYQD-- 992
GYYG CR C C S + GC G +C C G G +C+RCA G++
Sbjct: 1721 GYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKF 1780
Query: 993 -GSCTPCDCPHT--QNTCDPETGECVCPPHTQGVKCEECED 1030
GSC PC C +C P TG+C+ EEC+D
Sbjct: 1781 GGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDD 1821
Score = 107 bits (267), Expect = 2e-22
Identities = 69/220 (31%), Positives = 91/220 (41%), Gaps = 33/220 (15%)
Query: 741 PCECHGHAA---ECNVHGVCIACAHNTTGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTI 797
PCECH A C+ G C N G C +C G YG P C+PC+C +
Sbjct: 1265 PCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPR------CKPCSCGRRL 1318
Query: 798 ASNNFSPTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNPTVPGESCVPCDCS--GNV 855
+ C C P CE C + + G C C+CS G +
Sbjct: 1319 CEE-MTGQCR-----------CPPRTVRPQCEVCETHSFSFHPMAG--CEGCNCSRRGTI 1364
Query: 856 DPSEAGHCDSVTGECLKCLGNTDGAHCERCADGFYGDAVTAKNCRACECHVKGSHSAVCH 915
+ + CD +G+C +C G C+RCA GFY C C C+ G+ VC
Sbjct: 1365 EAAMP-ECDRDSGQC-RCKPRITGRQCDRCASGFY----RFPECVPCNCNRDGTEPGVCD 1418
Query: 916 LETGLCDCKPNVTGQQCDQCLHGYYGLDSGH--GCRPCNC 953
TG C CK NV G +C+ C G + LD + GC C C
Sbjct: 1419 PGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFC 1458
Score = 98.6 bits (244), Expect = 8e-20
Identities = 63/179 (35%), Positives = 81/179 (45%), Gaps = 22/179 (12%)
Query: 916 LETGLCDCKPNVTGQQCDQCLHGYY----GLDSGHGCRPCNCSVAGSVSDGCTD-EGQC- 969
L +C C P G C C GYY GL +G C PCNC+ S+ C D G C
Sbjct: 1649 LAVEICACPPAYAGDSCQGCSPGYYRDHKGLYTGR-CVPCNCN---GHSNQCQDGSGICV 1704
Query: 970 HCVPGVAGKRCDRCAHGFYAYQ-DGSCTPCDCPHTQN---TCDPETGE--CVCPPHTQGV 1023
+C AG+ C+RC G+Y GSC C CPHT + C G+ C C G
Sbjct: 1705 NCQHNTAGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGT 1764
Query: 1024 KCEECEDGHWGYDAEVG--CQACNCSLVGSTHHRCDVVTGHC---QCKSKFGGRACDQC 1077
+CE C G++G + G CQ C+C+ G C +TG C + K CD C
Sbjct: 1765 QCERCAPGYFGNPQKFGGSCQPCSCNSNGQL-GSCHPLTGDCINQEPKDSSPAEECDDC 1822
Score = 88.6 bits (218), Expect = 9e-17
Identities = 67/252 (26%), Positives = 90/252 (35%), Gaps = 51/252 (20%)
Query: 1362 CVCPPGTVGFSCQDCAPGYHRGKL-------PAGSDRGPRPLVAPCVPCSCNNHS---DT 1411
C C P G +C+ CA GY+ P + P+ C CN +
Sbjct: 443 CHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEI 502
Query: 1412 CDPNTGKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLE-G 1470
CD + G+CL C G CD C SG+Y A C+ P +S + C G
Sbjct: 503 CDAH-GRCL-CRPGVEGPRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQCECRPG 560
Query: 1471 DHDFRCDACL-------------------------LGY-------EGKHCERCSSSYYGN 1498
RCD CL LGY EG C RC Y+
Sbjct: 561 VTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNLGYCQCKLHVEGPTCSRCKLLYWNL 620
Query: 1499 PQTPGGSCQKCDCNPHGSVHG--DCDRTSGQCVCRLGASGLRCDECEPRHILMETD---- 1552
+ C +C C+ G+V G +C + G C C+ G CD CE + +E
Sbjct: 621 DKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFG 680
Query: 1553 CVSCDDECVGVL 1564
C C + G L
Sbjct: 681 CQGCQCDIGGAL 692
Score = 71.2 bits (173), Expect = 1e-11
Identities = 58/223 (26%), Positives = 80/223 (35%), Gaps = 38/223 (17%)
Query: 1354 EVASLLENCVCPPGTVGFSCQDCAPGYHRG--------------KLPAGSDRGP---RPL 1396
E+ C+C PG G C C G++ ++P S G RP
Sbjct: 501 EICDAHGRCLCRPGVEGPRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQCECRPG 560
Query: 1397 VAP--CVPC--------SCNNHSDTCDP------NTGKCLNCGDNTAGDHCDVCTSGYYG 1440
V C C C S CDP N G C C + G C C Y+
Sbjct: 561 VTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNLGYC-QCKLHVEGPTCSRCKLLYWN 619
Query: 1441 KVTGSASDCALCACPHSPPASFSPTCVLEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQ 1500
+ S C+ C C + S + C +GD D C + + G C+ C Y+ +
Sbjct: 620 LDKENPSGCSECKCHKAGTVSGTGEC-RQGDGDCHCKSHV---GGDSCDTCEDGYFALEK 675
Query: 1501 TPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDECE 1543
+ CQ C C+ G++ C SG C CR G C E
Sbjct: 676 SNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQRPE 718
Score = 68.2 bits (165), Expect = 1e-10
Identities = 46/162 (28%), Positives = 71/162 (43%), Gaps = 25/162 (15%)
Query: 1403 CSCNNHSDTCDPNTGKCL---NCGDNTAGDHCDVCTSGYYGKVTGSAS-----DCALCAC 1454
C CN H++ C+ N + L C +T G+ CD C +GY + A+ +C C C
Sbjct: 299 CVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNC 358
Query: 1455 -PHSPPASFSP-------TCVLEGDH--DFRCDACLLGYEGKHCERCSSSY---YGNPQT 1501
H+ + P + +G + C C G +CE+C+ Y YG P
Sbjct: 359 HGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVD 418
Query: 1502 PGGSCQKCDCNPHGSVHGD-CDRTSGQCVCRLGASGLRCDEC 1542
C C C+P H D C++ SG+C C+ G C++C
Sbjct: 419 APDGCIPCSCDPE---HADGCEQGSGRCHCKPNFHGDNCEKC 457
Score = 44.3 bits (103), Expect = 0.002
Identities = 20/61 (32%), Positives = 26/61 (42%), Gaps = 2/61 (3%)
Query: 454 CGCNPVGSASDE--PCTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFCFGVSDV 511
C C+P G+ P G C C+ NV G+ C RC G Y P C C ++
Sbjct: 1266 CECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPRCKPCSCGRRLCEEMTGQ 1325
Query: 512 C 512
C
Sbjct: 1326 C 1326
Score = 40.4 bits (93), Expect = 0.027
Identities = 27/115 (23%), Positives = 47/115 (40%), Gaps = 22/115 (19%)
Query: 273 YGHASSCPWDETTK----------KLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGN 322
+G +CP T ++C C+ G C RC PGY P + G
Sbjct: 1728 HGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQK-----FGG 1782
Query: 323 TCEACNCHNKAK--DCY--YDESVAKQKKSLNTAGQFRGGGVCINCLQN---TMG 370
+C+ C+C++ + C+ + + ++ K + A + C+ L N TMG
Sbjct: 1783 SCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSCVMTLLNDLATMG 1837
Score = 39.7 bits (91), Expect = 0.046
Identities = 19/69 (27%), Positives = 28/69 (40%), Gaps = 15/69 (21%)
Query: 1493 SSYYGNPQTPGGSCQK---------------CDCNPHGSVHGDCDRTSGQCVCRLGASGL 1537
+S+Y +PQT C+ C+C+P G+ C GQC C+ G
Sbjct: 1235 NSFYLDPQTASRFCKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGR 1294
Query: 1538 RCDECEPRH 1546
+C C H
Sbjct: 1295 QCTRCATGH 1303
>gi|145309326 laminin, gamma 1 precursor [Homo sapiens]
Length = 1609
Score = 623 bits (1607), Expect = e-178
Identities = 380/1087 (34%), Positives = 542/1087 (49%), Gaps = 122/1087 (11%)
Query: 5 VLLVLLLCVAAQCRQRGL-------------FPAILNLASNAHISTNATCGEKGPEMFCK 51
VL VL AA C Q + P +N A N + TCG PE +C
Sbjct: 20 VLAVLAAAAAAGCAQAAMDECTDEGGRPQRCMPEFVNAAFNVTVVATNTCGTP-PEEYCV 78
Query: 52 LVEHVPGRPVRNPQCRICDGNSANPRERHPISHAIDGTNN----WWQSPSIQNGREY-HW 106
G C +CD + P +H + D N WWQS ++ G +Y
Sbjct: 79 QT----GVTGVTKSCHLCD--AGQPHLQHGAAFLTDYNNQADTTWWQSQTMLAGVQYPSS 132
Query: 107 VTITLDLRQVFQVAYVIIKAANAPRPGNWILERSLDGTTFSPWQYYAVSDSECLSRYNIT 166
+ +TL L + F + YV +K + I +R+ + + P+QYY+ S C + Y+
Sbjct: 133 INLTLHLGKAFDITYVRLKFHTSRPESFAIYKRTREDGPWIPYQYYSGS---CENTYSKA 189
Query: 167 PRRGPPTYRADDEVICTSYYSRLVPLEHGEIHTSLINGRPSAD--DLSPKLLEFTSARYI 224
R T + + +CT +S + PL G + S + GRPSA D SP L E+ +A I
Sbjct: 190 NRGFIRTGGDEQQALCTDEFSDISPLTGGNVAFSTLEGRPSAYNFDNSPVLQEWVTATDI 249
Query: 225 RLRLQRIRTLNADLMTLSHREPKELDPIVTRRYYYSIKDISVGGMCICYGHASSCPWDET 284
R+ L R+ T ++ DP V + YYY+I D +VGG C C GHAS C +E
Sbjct: 250 RVTLNRLNTFGDEVFN---------DPKVLKSYYYAISDFAVGGRCKCNGHASECMKNEF 300
Query: 285 TKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAK 344
K L C C+HNT G C +C P ++ +PWR T S + C C+C+ ++++CY+D + +
Sbjct: 301 DK-LVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCNGRSQECYFDPELYR 359
Query: 345 QKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGS 404
GG C NC NT G +CE C + ++R +E C C+C PVGS
Sbjct: 360 STGH---------GGHCTNCQDNTDGAHCERCRENFFRLGN-----NEACSSCHCSPVGS 405
Query: 405 LSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYPT--CVSCGCNPVGSA 462
LS+ C G+C CK G G+KCDRCQ G+ C C C+P GS
Sbjct: 406 LSTQC------------DSYGRCSCKPGVMGDKCDRCQPGFHSLTEAGCRPCSCDPSGSI 453
Query: 463 SDEPC---TGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFCFGVSDVC-SSLSWP 518
+ C TG CVCK+NVEG C+RCKPGF+NL+ NPRGC+ CFCFG S VC +++ +
Sbjct: 454 DE--CNIETGRCVCKDNVEGFNCERCKPGFFNLESSNPRGCTPCFCFGHSSVCTNAVGYS 511
Query: 519 VGQVNSM-----SGWLVTDLISPRKIPSQQDALGGRHQVSINNTAVMQRLAPKYYWAAPE 573
V ++S GW + + R +++ + + R Y+ AP
Sbjct: 512 VYSISSTFQIDEDGWRAEQRDGSE---ASLEWSSERQDIAVISDSYFPR-----YFIAPA 563
Query: 574 AYLGNKLTAFGGFLKYTVSYDIPVETVDSNLMSHADVIIKGNGLTLSTQ--AEGLSLQPY 631
+LG ++ ++G +S+ V+ D+ L S D++++G GL +S A+G S
Sbjct: 564 KFLGKQVLSYG----QNLSFSFRVDRRDTRL-SAEDLVLEGAGLRVSVPLIAQGNSYPSE 618
Query: 632 EEYLNVVRLVPENFQDFHSKRQIDRDQLMTVLANVTHLLIRANYNSAKMALYRLESVSLD 691
V RL D+ + + + +L N+T + IR Y S + A Y L+ V+L
Sbjct: 619 TTVKYVFRL--HEATDYPWRPALTPFEFQKLLNNLTSIKIRGTY-SERSAGY-LDDVTL- 673
Query: 692 IASSNAIDLVVAADVEHCECPQGYTGTSCESCLSGYYRVDGILFG-GICQPCECHGHAAE 750
AS+ V A VE C CP GY G CE CLSGY R L C C C+GH+
Sbjct: 674 -ASARPGPGVPATWVESCTCPVGYGGQFCEMCLSGYRRETPNLGPYSPCVLCACNGHSET 732
Query: 751 CNVH-GVCIACAHNTTGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLN 809
C+ GVC C NT G HCE+C G+YG+ + GT DCQPC CP S +
Sbjct: 733 CDPETGVC-NCRDNTAGPHCEKCSDGYYGDSTAGTSSDCQPCPCP------GGSSCAVVP 785
Query: 810 DGDEVVCDWCAPGYSGAWCERCADGYYGNP---TVPGESCVPCDCSGNVDPSEAGHCDSV 866
EVVC C G +G CE C DGY+G+P P C C CS N+DP+ G+C+ +
Sbjct: 786 KTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNRL 845
Query: 867 TGECLKCLGNTDGAHCERCADGFYGDAVT---AKNCRACECHVKGS--HSAVCHLETGLC 921
TGECLKC+ NT G +C+RC DGF+G+ + A C+AC C++ G+ + C+ TG C
Sbjct: 846 TGECLKCIYNTAGFYCDRCKDGFFGNPLAPNPADKCKACNCNLYGTMKQQSSCNPVTGQC 905
Query: 922 DCKPNVTGQQCDQCLHGYYGLDSGHGCRPCNCSVAGSVSDGC-TDEGQCHCVPGVAGKRC 980
+C P+VTGQ C C G+Y L SG GC C+C GS + C GQC C PG+ G+ C
Sbjct: 906 ECLPHVTGQDCGACDPGFYNLQSGQGCERCDCHALGSTNGQCDIRTGQCECQPGITGQHC 965
Query: 981 DRCAHGFYAYQDGSCTPCDCPHTQNTCD---PETGECVCPPHTQGVKCEECEDGHWGYDA 1037
+RC + + C PCDC H + + + G C C G +C++CE+ ++ +
Sbjct: 966 ERCEVNHFGFGPEGCKPCDC-HPEGSLSLQCKDDGRCECREGFVGNRCDQCEENYFYNRS 1024
Query: 1038 EVGCQAC 1044
GCQ C
Sbjct: 1025 WPGCQEC 1031
Score = 286 bits (733), Expect = 2e-76
Identities = 198/641 (30%), Positives = 284/641 (44%), Gaps = 85/641 (13%)
Query: 939 YYGLDSGHGCRPCNCSVAGSVSDGCTDEGQ---CHCVPGVAGKRCDRCAHGFY------- 988
YY + C C+ G S+ +E C+C G C++C F
Sbjct: 274 YYAISDFAVGGRCKCN--GHASECMKNEFDKLVCNCKHNTYGVDCEKCLPFFNDRPWRRA 331
Query: 989 -AYQDGSCTPCDCPHTQNTC--DPET-------GECV-CPPHTQGVKCEECEDGHWGYDA 1037
A C PCDC C DPE G C C +T G CE C + +
Sbjct: 332 TAESASECLPCDCNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFRLGN 391
Query: 1038 EVGCQACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGYRDFPD--CVPCDCDLR 1095
C +C+CS VGS +CD G C CK G CD+C G+ + C PC CD
Sbjct: 392 NEACSSCHCSPVGSLSTQCDSY-GRCSCKPGVMGDKCDRCQPGFHSLTEAGCRPCSCDPS 450
Query: 1096 GTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFALRADNPLGCSPCFCSGL 1155
G S D CN+E TG C CK+NV G C C+ G F L + NP GC+PCFC G
Sbjct: 451 G-SIDECNIE---------TGRCVCKDNVEGFNCERCKPGFFNLESSNPRGCTPCFCFGH 500
Query: 1156 SHLCSELEDYVRTPV--TLGSDQPLLRVVSQSNLRGTTEGVYYQAPDFLLDAATVRQHIR 1213
S +C+ Y + T D+ R + + E + D A +
Sbjct: 501 SSVCTNAVGYSVYSISSTFQIDEDGWRAEQRDGSEASLEWSSERQ-----DIAVISDSYF 555
Query: 1214 AEPFYWRLPQQFQGDQLMAYGGKLKYSVAFYSLDGVGTSNFEPQVLIKGGRIRKQVIYMD 1273
P Y+ P +F G Q+++YG L +S + +D T ++++G +R V
Sbjct: 556 --PRYFIAPAKFLGKQVLSYGQNLSFS---FRVDRRDTRLSAEDLVLEGAGLRVSV---- 606
Query: 1274 APAPENGVRQEQEVAMRENFWKYFNSVSEKP----VTREDFMSVLSDIEYILIKASYGQG 1329
P G E ++ F + ++ P +T +F +L+++ I I+ +Y +
Sbjct: 607 -PLIAQGNSYPSETTVKYVF--RLHEATDYPWRPALTPFEFQKLLNNLTSIKIRGTYSER 663
Query: 1330 LQQSRISDISMEVGRKAEKLHPEEEVASLLENCVCPPGTVGFSCQDCAPGYHRGKLPAGS 1389
+ D+++ R + A+ +E+C CP G G C+ C GY R
Sbjct: 664 -SAGYLDDVTLASARPGPGVP-----ATWVESCTCPVGYGGQFCEMCLSGYRRET----P 713
Query: 1390 DRGPRPLVAPCVPCSCNNHSDTCDPNTGKCLNCGDNTAGDHCDVCTSGYYGKVT-GSASD 1448
+ GP +PCV C+CN HS+TCDP TG C NC DNTAG HC+ C+ GYYG T G++SD
Sbjct: 714 NLGP---YSPCVLCACNGHSETCDPETGVC-NCRDNTAGPHCEKCSDGYYGDSTAGTSSD 769
Query: 1449 CALCACPHSPPASFSPTCVLEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQTPGGS--- 1505
C C CP S V+ + C C G GK CE C Y+G+P G
Sbjct: 770 CQPCPCPGG-----SSCAVVPKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRL 824
Query: 1506 CQKCDC--NPHGSVHGDCDRTSGQCV-CRLGASGLRCDECE 1543
C+ C C N + G+C+R +G+C+ C +G CD C+
Sbjct: 825 CRLCQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCK 865
Score = 216 bits (551), Expect = 2e-55
Identities = 120/358 (33%), Positives = 174/358 (48%), Gaps = 44/358 (12%)
Query: 819 CAPGYSGAWCERCADGYYGN-PTV-PGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGN 876
C GY G +CE C GY P + P CV C C+G+ + CD TG C C N
Sbjct: 692 CPVGYGGQFCEMCLSGYRRETPNLGPYSPCVLCACNGHSET-----CDPETGVC-NCRDN 745
Query: 877 TDGAHCERCADGFYGDAV--TAKNCRACECHVKGSHSAVCHLETGLC-DCKPNVTGQQCD 933
T G HCE+C+DG+YGD+ T+ +C+ C C S + V + +C +C TG++C+
Sbjct: 746 TAGPHCEKCSDGYYGDSTAGTSSDCQPCPCPGGSSCAVVPKTKEVVCTNCPTGTTGKRCE 805
Query: 934 QCLHGYYGLDSGHG-----CRPCNCS--VAGSVSDGCTD-EGQC-HCVPGVAGKRCDRCA 984
C GY+G G CR C CS + + C G+C C+ AG CDRC
Sbjct: 806 LCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCK 865
Query: 985 HGFYAYQ-----DGSCTPCDCP-----HTQNTCDPETGECVCPPHTQGVKCEECEDGHWG 1034
GF+ C C+C Q++C+P TG+C C PH G C C+ G +
Sbjct: 866 DGFFGNPLAPNPADKCKACNCNLYGTMKQQSSCNPVTGQCECLPHVTGQDCGACDPGFYN 925
Query: 1035 YDAEVGCQACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGYRDF--PDCVPCDC 1092
+ GC+ C+C +GST+ +CD+ TG C+C+ G+ C++C + + F C PCDC
Sbjct: 926 LQSGQGCERCDCHALGSTNGQCDIRTGQCECQPGITGQHCERCEVNHFGFGPEGCKPCDC 985
Query: 1093 DLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFALRADNPLGCSPC 1150
G+ C ++ G C C+E G +C++C E F R+ GC C
Sbjct: 986 HPEGSLSLQC----------KDDGRCECREGFVGNRCDQCEENYFYNRSWP--GCQEC 1031
Score = 164 bits (415), Expect = 1e-39
Identities = 108/356 (30%), Positives = 147/356 (41%), Gaps = 60/356 (16%)
Query: 853 GNVDPSEAGHCDSVT--------------GECLKCLGNTDGAHCERCADGFYGDAVTA-- 896
G AG+ D VT E C G CE C G+ +
Sbjct: 658 GTYSERSAGYLDDVTLASARPGPGVPATWVESCTCPVGYGGQFCEMCLSGYRRETPNLGP 717
Query: 897 -KNCRACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLDSGHG----CRPC 951
C C C+ HS C ETG+C+C+ N G C++C GYYG DS G C+PC
Sbjct: 718 YSPCVLCACN---GHSETCDPETGVCNCRDNTAGPHCEKCSDGYYG-DSTAGTSSDCQPC 773
Query: 952 NCSVAGSVSD-GCTDEGQC-HCVPGVAGKRCDRCAHGFYAYQDGS------CTPCDC--- 1000
C S + T E C +C G GKRC+ C G++ G C C C
Sbjct: 774 PCPGGSSCAVVPKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQCSDN 833
Query: 1001 --PHTQNTCDPETGECV-CPPHTQGVKCEECEDGHWGYDAEVG----CQACNCSLVGSTH 1053
P+ C+ TGEC+ C +T G C+ C+DG +G C+ACNC+L G+
Sbjct: 834 IDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKDGFFGNPLAPNPADKCKACNCNLYGTMK 893
Query: 1054 HR--CDVVTGHCQCKSKFGGRACDQCSLGYRDFPD---CVPCDCDLRGTSGDACNLEQGL 1108
+ C+ VTG C+C G+ C C G+ + C CDC G++ C++
Sbjct: 894 QQSSCNPVTGQCECLPHVTGQDCGACDPGFYNLQSGQGCERCDCHALGSTNGQCDIR--- 950
Query: 1109 CGCVEETGACPCKENVFGPQCNECREGTFALRADNPLGCSPCFCSGLSHLCSELED 1164
TG C C+ + G C C F P GC PC C L + +D
Sbjct: 951 ------TGQCECQPGITGQHCERCEVNHFGF---GPEGCKPCDCHPEGSLSLQCKD 997
Score = 134 bits (338), Expect = 1e-30
Identities = 68/219 (31%), Positives = 101/219 (46%), Gaps = 28/219 (12%)
Query: 849 CDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCADGFYGD-------AVTAKNCRA 901
C C+G+ D + C NT G CE+C F+ D A +A C
Sbjct: 286 CKCNGHASECMKNEFDKLV---CNCKHNTYGVDCEKCLP-FFNDRPWRRATAESASECLP 341
Query: 902 CECHVKGSHSAVCHLETGL----------CDCKPNVTGQQCDQCLHGYYGLDSGHGCRPC 951
C+C+ S C+ + L +C+ N G C++C ++ L + C C
Sbjct: 342 CDCN---GRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFRLGNNEACSSC 398
Query: 952 NCSVAGSVSDGCTDEGQCHCVPGVAGKRCDRCAHGFYAYQDGSCTPCDCPHTQ--NTCDP 1009
+CS GS+S C G+C C PGV G +CDRC GF++ + C PC C + + C+
Sbjct: 399 HCSPVGSLSTQCDSYGRCSCKPGVMGDKCDRCQPGFHSLTEAGCRPCSCDPSGSIDECNI 458
Query: 1010 ETGECVCPPHTQGVKCEECEDGHWGYDAE--VGCQACNC 1046
ETG CVC + +G CE C+ G + ++ GC C C
Sbjct: 459 ETGRCVCKDNVEGFNCERCKPGFFNLESSNPRGCTPCFC 497
Score = 130 bits (328), Expect = 2e-29
Identities = 184/828 (22%), Positives = 308/828 (37%), Gaps = 153/828 (18%)
Query: 1364 CPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSD-----TCDPNTGK 1418
CP GT G C+ C GY G G V C C C+++ D C+ TG+
Sbjct: 795 CPTGTTGKRCELCDDGYF------GDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNRLTGE 848
Query: 1419 CLNCGDNTAGDHCDVCTSGYYGK--VTGSASDCALCAC---------------------- 1454
CL C NTAG +CD C G++G A C C C
Sbjct: 849 CLKCIYNTAGFYCDRCKDGFFGNPLAPNPADKCKACNCNLYGTMKQQSSCNPVTGQCECL 908
Query: 1455 PH-----------------SPPASFSPTCVLEGDHDFRCDA------CLLGYEGKHCERC 1491
PH S C G + +CD C G G+HCERC
Sbjct: 909 PHVTGQDCGACDPGFYNLQSGQGCERCDCHALGSTNGQCDIRTGQCECQPGITGQHCERC 968
Query: 1492 SSSYYG-NPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDECEPRHILME 1550
+++G P+ C+ CDC+P GS+ C + G+C CR G G RCD+CE +
Sbjct: 969 EVNHFGFGPE----GCKPCDCHPEGSLSLQC-KDDGRCECREGFVGNRCDQCEENY-FYN 1022
Query: 1551 TDCVSCDDECVGVLLNDLDEIGDAVLSLNLTGIIPVPYGILSNLENTTKYLQESLLKENM 1610
C EC D++ D + L + G + E T E LKE
Sbjct: 1023 RSWPGC-QECPACYRLVKDKVADHRVKLQELESLIANLG--TGDEMVTDQAFEDRLKEAE 1079
Query: 1611 QKDLGKIK-LEGVAEETDNLQKKLTRMLASTQKVNRATERIFKESQDLAIAIERLQMSIT 1669
++ + ++ + V + NL +L Q+VN L+ I RLQ
Sbjct: 1080 REVMDLLREAQDVKDVDQNLMDRL-------QRVNNT----------LSSQISRLQ---- 1118
Query: 1670 EIMEKTTLNQTLDEDFLLPNSTLQNMQQNGTSLLEIMQIRDFTQLHQNATLEL---KAAE 1726
+ T++E L ++ +N L+EI A+ EL K A
Sbjct: 1119 ------NIRNTIEETGNLAEQARAHV-ENTERLIEI------------ASRELEKAKVAA 1159
Query: 1727 DLLSQIQENYQKPLEELEVLKEAASHVLSKHNNELKAAEALVREAEAKMQESNHLLL--M 1784
+S Q + +L E A + +H E + + A E+ +LLL +
Sbjct: 1160 ANVSVTQPESTGDPNNMTLLAEEARKLAERHKQEADDIVRVAKTANDTSTEAYNLLLRTL 1219
Query: 1785 VNANLREFSDKKLHVQEEQ--NLTSELIVQGRGLIDAAAAQTDAVQDALEHLEDHQDKLL 1842
N F ++L+ + EQ N++ +L Q + + A D A+E
Sbjct: 1220 AGENQTAFEIEELNRKYEQAKNISQDLEKQAARVHEEAKRAGD---KAVEIYASVAQLSP 1276
Query: 1843 LWSAKIRHHIDDLVMHMSQRNAVDLVYRAEDHAAEFQRLADVLYSGLENIRNVSLNATSA 1902
L S + + +++ M A +L + +++ L + + ++N+ +
Sbjct: 1277 LDSETLENEANNIKM-----EAENLEQLIDQKLKDYEDLREDMRGKELEVKNLLEKGKTE 1331
Query: 1903 AYVHYNIQSLIEESEELARDAHRTVTETSLLSESLVSNGKAAVQRSSRFLKEGNNLSRKL 1962
+ + + ++ LA +A + +T + +++N K +R + RK+
Sbjct: 1332 QQTADQLLARADAAKALAEEAAKKGRDTLQEANDILNNLKDFDRRVNDNKTAAEEALRKI 1391
Query: 1963 PGIALELSELRNKTNRFQE-------NAVEITRQTNESLLILRAIPKGIRDKGAKTKELA 2015
P I ++E KT Q+ +A E + +E+ I A+ K A
Sbjct: 1392 PAINQTITEANEKTREAQQALGSAAADATEAKNKAHEAERIASAVQKN-----------A 1440
Query: 2016 TSASQSAVSTLRDVAGLSQELLNTSASLSRVNTTLRETHQLLQDSTMATLLAGRKVKDVE 2075
TS A T +V L E+ N L L+ M +A + ++ E
Sbjct: 1441 TSTKAEAERTFAEVTDLDNEVNNMLKQLQEAEKELKRKQDDADQDMMMAGMASQAAQEAE 1500
Query: 2076 IQA-----------NLLFDRLKPLKMLEENLSRNLSEIKLLISQARKQ 2112
I A +++ D L+ L L+ L+EI+ +++A+ +
Sbjct: 1501 INARKAKNSVTSLLSIINDLLEQLGQLDTVDLNKLNEIEGTLNKAKDE 1548
Score = 111 bits (277), Expect = 1e-23
Identities = 70/233 (30%), Positives = 102/233 (43%), Gaps = 32/233 (13%)
Query: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTC--DPNT--- 1416
C C T G C+ C P ++ R + C+PC CN S C DP
Sbjct: 305 CNCKHNTYGVDCEKCLPFFNDRPWR----RATAESASECLPCDCNGRSQECYFDPELYRS 360
Query: 1417 ----GKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGDH 1472
G C NC DNT G HC+ C ++ G+ C+ C C SP S S C D
Sbjct: 361 TGHGGHCTNCQDNTDGAHCERCRENFFR--LGNNEACSSCHC--SPVGSLSTQC----DS 412
Query: 1473 DFRCDACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRL 1532
RC +C G G C+RC ++ + C+ C C+P GS+ +C+ +G+CVC+
Sbjct: 413 YGRC-SCKPGVMGDKCDRCQPGFHSLTE---AGCRPCSCDPSGSI-DECNIETGRCVCKD 467
Query: 1533 GASGLRCDECEPRHILMETD----CVSCDDECVGVLLNDLDEIGDAVLSLNLT 1581
G C+ C+P +E+ C C C G + +G +V S++ T
Sbjct: 468 NVEGFNCERCKPGFFNLESSNPRGCTPC--FCFGHSSVCTNAVGYSVYSISST 518
Score = 97.4 bits (241), Expect = 2e-19
Identities = 62/191 (32%), Positives = 83/191 (43%), Gaps = 16/191 (8%)
Query: 1403 CSCNNHSDTCDPNTGKCL--NCGDNTAGDHCDVCTSGYYGK-----VTGSASDCALCAC- 1454
C CN H+ C N L NC NT G C+ C + + SAS+C C C
Sbjct: 286 CKCNGHASECMKNEFDKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCN 345
Query: 1455 PHSPPASFSPTCVLEGDHDFRCDACLLGYEGKHCERCSSSYY--GNPQTPGGSCQKCDCN 1512
S F P H C C +G HCERC +++ GN + +C C C+
Sbjct: 346 GRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFRLGNNE----ACSSCHCS 401
Query: 1513 PHGSVHGDCDRTSGQCVCRLGASGLRCDECEPR-HILMETDCVSCDDECVGVLLNDLDEI 1571
P GS+ CD + G+C C+ G G +CD C+P H L E C C + G + E
Sbjct: 402 PVGSLSTQCD-SYGRCSCKPGVMGDKCDRCQPGFHSLTEAGCRPCSCDPSGSIDECNIET 460
Query: 1572 GDAVLSLNLTG 1582
G V N+ G
Sbjct: 461 GRCVCKDNVEG 471
Score = 85.5 bits (210), Expect = 7e-16
Identities = 152/778 (19%), Positives = 286/778 (36%), Gaps = 125/778 (16%)
Query: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDT---CDPNTGK 1418
C C P G C C PG++ + G +R C C+ T CD TG+
Sbjct: 905 CECLPHVTGQDCGACDPGFYNLQSGQGCER-----------CDCHALGSTNGQCDIRTGQ 953
Query: 1419 CLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGDHDFRCDA 1478
C C G HC+ C ++G C C C P S S C +G RC+
Sbjct: 954 C-ECQPGITGQHCERCEVNHFG---FGPEGCKPCDC--HPEGSLSLQCKDDG----RCE- 1002
Query: 1479 CLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLR 1538
C G+ G C++C +Y+ N PG CQ+C C R ++ ++
Sbjct: 1003 CREGFVGNRCDQCEENYFYNRSWPG--CQECPA---------CYRLVKD---KVADHRVK 1048
Query: 1539 CDECEPRHILMETDCVSCDDECVGVLLNDLD-EIGDAVLSLNLTGIIPVPYGILSNLENT 1597
E E + T D+ L + + E+ D L + V ++ L+
Sbjct: 1049 LQELESLIANLGTGDEMVTDQAFEDRLKEAEREVMD--LLREAQDVKDVDQNLMDRLQRV 1106
Query: 1598 TKYLQESLLKENMQKDLGKIKLEGVAEETDNLQKKLTRMLASTQKVNRATERIFKESQDL 1657
L + + + EET NL ++ + +T+++ R ++++
Sbjct: 1107 NNTLSSQISRLQ--------NIRNTIEETGNLAEQARAHVENTERLIEIASRELEKAKVA 1158
Query: 1658 AIAIERLQMSITEIMEKTTLNQTLDEDFLLPNSTLQNMQQNGTSLLEIMQIRDFTQLH-Q 1716
A + Q T TL L E+ + +Q ++ + + + T
Sbjct: 1159 AANVSVTQPESTGDPNNMTL---LAEE---ARKLAERHKQEADDIVRVAKTANDTSTEAY 1212
Query: 1717 NATLELKAAEDLLSQIQENYQKPLEELEVLKEAASHVLSKHNNELKAA------------ 1764
N L A E+ + E + E+ + + + ++ + E K A
Sbjct: 1213 NLLLRTLAGENQTAFEIEELNRKYEQAKNISQDLEKQAARVHEEAKRAGDKAVEIYASVA 1272
Query: 1765 -------EALVREAEAKMQESNHLLLMVNANLREFSDKKLHVQEEQNLTSELIVQGR--- 1814
E L EA E+ +L +++ L+++ D + ++ ++ L+ +G+
Sbjct: 1273 QLSPLDSETLENEANNIKMEAENLEQLIDQKLKDYEDLREDMRGKELEVKNLLEKGKTEQ 1332
Query: 1815 GLIDAAAAQTDAVQDALEHLEDHQDKLLLWSAKIRHHIDDLVMHMSQRNAVDLVYRAEDH 1874
D A+ DA + E L + I +++ D R D AE+
Sbjct: 1333 QTADQLLARADAAKALAEEAAKKGRDTLQEANDILNNLKDF-----DRRVNDNKTAAEEA 1387
Query: 1875 AAEFQRLADVLYSGLENIRNVSLNATSAAYVHYNIQSLIEESEELARDAHRTVTETSLLS 1934
+ + + E R SAA ++ E+E +A + T T +
Sbjct: 1388 LRKIPAINQTITEANEKTREAQQALGSAAADATEAKNKAHEAERIASAVQKNATSTKAEA 1447
Query: 1935 ESLVSNGKAAVQRSSRFLKEGNNLSRKLPGIALELSELRNKTNRFQENAVEITRQTNESL 1994
E R E +L ++ + +L E + R Q++A ++ +
Sbjct: 1448 E--------------RTFAEVTDLDNEVNNMLKQLQEAEKELKRKQDDA-------DQDM 1486
Query: 1995 LILRAIPKGIRDKGAKTKEL-ATSASQSAVSTLRDVAGLSQEL--LNT--SASLSRVNTT 2049
++ G+ + A+ E+ A A S S L + L ++L L+T L+ + T
Sbjct: 1487 MM-----AGMASQAAQEAEINARKAKNSVTSLLSIINDLLEQLGQLDTVDLNKLNEIEGT 1541
Query: 2050 LRETHQLLQDSTMATLLAGRKVKDVEIQAN----LLFDRLKPLKMLEENLSRNLSEIK 2103
L + ++ S + RKV D+E +A + D + ++ + +++ RNL +I+
Sbjct: 1542 LNKAKDEMKVSDL-----DRKVSDLENEAKKQEAAIMDYNRDIEEIMKDI-RNLEDIR 1593
Score = 52.0 bits (123), Expect = 9e-06
Identities = 38/124 (30%), Positives = 51/124 (41%), Gaps = 24/124 (19%)
Query: 709 CECPQGYTGTSCESCLSGYYRVDGILFGGI-CQPCECHGHAA---ECNVHGVCIACAHNT 764
CEC G TG CE C V+ FG C+PC+CH + +C G C C
Sbjct: 954 CECQPGITGQHCERC-----EVNHFGFGPEGCKPCDCHPEGSLSLQCKDDGRC-ECREGF 1007
Query: 765 TGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNNF-----------SPTCHLNDGDE 813
G C+QC ++ +R PG CQ C + + S +L GDE
Sbjct: 1008 VGNRCDQCEENYF--YNRSWPG-CQECPACYRLVKDKVADHRVKLQELESLIANLGTGDE 1064
Query: 814 VVCD 817
+V D
Sbjct: 1065 MVTD 1068
>gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens]
Length = 3277
Score = 611 bits (1576), Expect = e-174
Identities = 587/2230 (26%), Positives = 930/2230 (41%), Gaps = 321/2230 (14%)
Query: 947 GCRPCNCSVAGSVSDGCTDEG-QCHCVPGVAGKRCDRCAHGFYAYQDGSCTPCDCPHTQN 1005
G PC C G+ C+ EG QC C P V G++C RCA G Y + C PC C +
Sbjct: 1262 GALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFP--RCKPCSCG--RR 1317
Query: 1006 TCDPETGECVCPPHTQGVKCEECEDGHWGYDAEVGCQACNCSLVGSTHH---RCDVVTGH 1062
C+ TG+C CPP T +CE CE + + GC+ CNCS G+ CD +G
Sbjct: 1318 LCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQ 1377
Query: 1063 CQCKSKFGGRACDQCSLGYRDFPDCVPCDCDLRGTSGDACNLEQGLCGCVEETGACPCKE 1122
C+CK + GR CD+C+ G+ FP+CVPC+C+ GT E G+C TGAC CKE
Sbjct: 1378 CRCKPRITGRQCDRCASGFYRFPECVPCNCNRDGT-------EPGVCD--PGTGACLCKE 1428
Query: 1123 NVFGPQCNECREGTFALRADNPLGCSPCFCSGLSHLCS-----------------ELEDY 1165
NV G +CN CREG+F L N GC+ CFC G+++ C E D
Sbjct: 1429 NVEGTECNVCREGSFHLDPANLKGCTSCFCFGVNNQCHSSHKRRTKFVDMLGWHLETADR 1488
Query: 1166 VRTPVTLGSDQPLLRVVSQSNLRGTTEGVYYQAPDFLLDAATVRQHIRAEPFYWRLPQQF 1225
V PV+ + V L T W P +
Sbjct: 1489 VDIPVSFNPGSNSM-VADLQELPATIHSAS-----------------------WVAPTSY 1524
Query: 1226 QGDQLMAYGGKLKYSVAFYSLDG-VGTSNFEPQVLIKGGRIRKQVIYMDAPAPENGVRQE 1284
GD++ +YGG L Y + L G + +P V + G + +IY + P
Sbjct: 1525 LGDKVSSYGGYLTYQAKSFGLPGDMVLLEKKPDVQLTGQHM--SIIYEETNTPRPDRLHH 1582
Query: 1285 QEVAMRENFWKYFNSVSEKPVTREDFMSVLSDIEYILIKASYGQGLQQSRISDISMEVGR 1344
V + E +++ +S PV+RE+ M+VLS + + I+ Y Q+ +S++ +E
Sbjct: 1583 GRVHVVEGNFRHASS--RAPVSREELMTVLSRLADVRIQGLYFTETQRLTLSEVGLEEAS 1640
Query: 1345 KAEKLHPEEEVASLLENCVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCS 1404
+A +E C CPP G SCQ C+PGY+R + R CVPC+
Sbjct: 1641 DTGS----GRIALAVEICACPPAYAGDSCQGCSPGYYRDHKGLYTGR--------CVPCN 1688
Query: 1405 CNNHSDTCDPNTGKCLNCGDNTAGDHCDVCTSGYYGK-VTGSASDCALCACPHSPPASFS 1463
CN HS+ C +G C+NC NTAG+HC+ C GYYG V GS C C CPH+ SF+
Sbjct: 1689 CNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGS---CRACPCPHT--NSFA 1743
Query: 1464 PTCVLEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDR 1523
CV+ G D RC +C GY G CERC+ Y+GNPQ GGSCQ C CN +G + G C
Sbjct: 1744 TGCVVNGG-DVRC-SCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQL-GSCHP 1800
Query: 1524 TSGQCVCRLGASGLRCDECEPRHILMETDCVSCDDECVGVLLNDLDEIGD--AVLSLNLT 1581
+G C+ + +EC+ DC D CV LLNDL +G+ ++ L
Sbjct: 1801 LTGDCINQEPKDSSPAEECD--------DC----DSCVMTLLNDLATMGEQLRLVKSQLQ 1848
Query: 1582 GIIPVPYGILS---NLENTTKYLQESLLKENMQKDLGKIKLEGVAEETDNLQKKLTRMLA 1638
G + G+L ++E K L+ LL K+EG+ E +L ++ +
Sbjct: 1849 G-LSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDLNQEFETLQE 1907
Query: 1639 STQKVNRATERIFKESQDLAIAIERLQMSITEIMEKTTLNQTLDEDFLLPNSTLQNMQQN 1698
Q +R ++Q L + R S E+ K ++N+ +N
Sbjct: 1908 KAQVNSR-------KAQTLNNNVNRATQSAKELDVK-----------------IKNVIRN 1943
Query: 1699 GTSLLEIMQIRDFTQLHQNATLELKAAEDLLSQIQENYQKPLEELEVLKEAASHVLSKHN 1758
+ + +IR + + HQ L A + + E Y+ L +L
Sbjct: 1944 ---VHMLNRIRTWQKTHQGENNGL--ANSIRDSLNE-YEAKLSDLRA------------- 1984
Query: 1759 NELKAAEALVREAEAKMQESNHLLLMVNANLREFSDKKLHVQEEQNLTSELIVQGRGLID 1818
L+ A A ++A QE+ L + ++E + + + T L L+
Sbjct: 1985 -RLQEAAAQAKQANGLNQENERALGAIQRQVKEINSL------QSDFTKYLTTADSSLL- 2036
Query: 1819 AAAAQTDAVQDALEHLEDHQDKLLLWSAKIRHHIDDLVMHMSQ-RNAVDLVYRAEDHAAE 1877
QT+ +E + +KL + R + D V +S+ LV AE HA
Sbjct: 2037 ----QTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRELSRSAGKTSLVEEAEKHARS 2092
Query: 1878 FQRLADVLYSGLENIRNVSL--NATSAAYVHYNIQSLIEESEELARDAHRTVTETSL--- 1932
Q LA L N L A AA + NI + I+ +E+ A A + +E++L
Sbjct: 2093 LQELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIKAAEDAANRA-ASASESALQTV 2151
Query: 1933 LSESLVSNGKAAVQRSSRFLKEGNNLSRKLPGIALELSELRNKTNRFQENAVEITRQTNE 1992
+ E L K S + L E +KL E+ N Q+ +T Q
Sbjct: 2152 IKEDLPRKAKTLSSNSDKLLNEAKMTQKKLK------QEVSPALNNLQQTLNIVTVQKEV 2205
Query: 1993 SLLILRAIPKGIRDKGAKTKELATSASQSAVSTLRDVAGLSQELLN-TSASLSRVNTTLR 2051
L + G+ + S+++S V D+ + LN + R+ T
Sbjct: 2206 IDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIKDTYG 2265
Query: 2052 ETH-----QLLQDSTMATLLAGRKVKDVEIQANLLFDRLKPLKMLEENLSRNLSEIKLLI 2106
T + L D+ + K+ D+ + + +L PL N+S N+ I+ LI
Sbjct: 2266 RTQNEDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPL----GNISDNMDRIRELI 2321
Query: 2107 SQARKQAASIKVAVSAD-RDCIRAYQPQISSTNYNTLTLNVKTQEPDN---------LLF 2156
QAR A+ + V + + + + P +L++ Q P++ +
Sbjct: 2322 QQARDAASKVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQRPNSRENGGTENMFVM 2381
Query: 2157 YLGSSTAS-DFLAVEMRRGRVAFLWDLGSGSTRLEFPDFPIDDNRWHSIHVARFGNIGSL 2215
YLG+ AS D++ + + G++ +++LG L+ ++ +
Sbjct: 2382 YLGNKDASRDYIGMAVVDGQLTCVYNLGDREAELQVDQILTKSETKEAV----MDRVKFQ 2437
Query: 2216 SVKEMSSNQKSPTKTSKSPGTANVLDV---NNSTLM---------FVGGLGGQIKKSPAV 2263
+ + + + TS P T V D+ N++TL+ +VGG K +
Sbjct: 2438 RIYQFARLNYTKGATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGYPPDFKLPSRL 2497
Query: 2264 KVTHFKGCLGEAFLNGKSIGLWNYIE----REGKCRGCFGSSQNEDPSFHFDGSGYSVVE 2319
+KGC+ LN + L+N+ + + C + D ++ F+G+GY+ V
Sbjct: 2498 SFPPYKGCIELDDLNENVLSLYNFKKTFNLNTTEVEPCRRRKEESDKNY-FEGTGYARVP 2556
Query: 2320 KSLPATVTQIIMLFNTFSPNGLLLYLGSYGTKDFLSIELFRGRVKVMTDLGSG-PITLLT 2378
A + T GLL + + F+S+ + G++ V L S P
Sbjct: 2557 TQPHAPIPTFGQTIQTTVDRGLLFF--AENGDRFISLNIEDGKLMVRYKLNSELPKERGV 2614
Query: 2379 DRRYNNGTWYKIAFQRNRKQGVLAV-IDAYNTSNKETKQGETPGASSDLNRLDKDPIYVG 2437
NNG + I + + Q + + +D NT GE D Y+G
Sbjct: 2615 GDAINNGRDHSIQIKIGKLQKRMWINVDVQNT----IIDGEV---------FDFSTYYLG 2661
Query: 2438 GLPRSRVVRRGVTTKSFVGCIKNLEISRSTFDLLRNSYGVRKGCL--LEPIRSVSFLKGG 2495
G+P + R ++T +F GC+KNL+ S L ++ GV K C + +RS SF +GG
Sbjct: 2662 GIPIAIRERFNISTPAFRGCMKNLK-KTSGVVRLNDTVGVTKKCSEDWKLVRSASFSRGG 2720
Query: 2496 YIELPPKSLSPESEWLVTFA--TTNSSGIILAALGGDVEKRGDREEAHVPFFSVMLIGGN 2553
+ L P +F T SGI+L + V L G
Sbjct: 2721 QLSFTDLGLPPTDHLQASFGFQTFQPSGILL------------DHQTWTRNLQVTLEDGY 2768
Query: 2554 IEVHVNPGDGTGLRKALLHAPTGTCSDGQAHSISLVRN----RRIITVQLDENNPVEMKL 2609
IE+ + G+ + K+ T DG H +S++ + R +I QL N+ +L
Sbjct: 2769 IELSTS-DSGSPIFKS-----PQTYMDGLLHYVSVISDNSGLRLLIDDQLLRNS---KRL 2819
Query: 2610 GTLVESRTINVSNLYVGGIPEGEGTSLLTMRRSFHGCIKN-----LIFNLELLDFNSAVG 2664
+ SR +L +GG +F GCI N L + E+LD S
Sbjct: 2820 KHISSSR----QSLRLGG-------------SNFEGCISNVFVQRLSLSPEVLDLTSNSL 2862
Query: 2665 HEQVDLDTCWLSERP------------KLAPDAEDSKLLPEPRAFPEQCVV-DAALEYVP 2711
V L C L++ P K + L P A P V A +P
Sbjct: 2863 KRDVSLGGCSLNKPPFLMLLKGSTRFNKTKTFRINQLLQDTPVASPRSVKVWQDACSPLP 2922
Query: 2712 ------GAHQFGLTQNSHFILPFNQSAVRKKLSVELSIRTFASSGLIYYMAHQNQADYAV 2765
GA QFG SH + Q ++ + + ++T +S GL+++ +N +
Sbjct: 2923 KTQANHGALQFGDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLVFHTGTKN--SFMA 2980
Query: 2766 LQLHGGRLHFMFDLGKGRTKVSHPALLSDGKWHTVKTDYVKRKGFITVDGRESPMVTVVG 2825
L L GRL F + ++ +DGKWHTV + KG + VDG + ++ G
Sbjct: 2981 LYLSKGRLVFALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPG 3040
Query: 2826 DGTMLDVEGLFYLGGLPSQYQARKIGNITHSIPACIGDVTVNSKQLDKDSPVSAFTVNRC 2885
+ T + + YLG PS + T+S C+ + ++SK L +P S+F V+ C
Sbjct: 3041 NST-ISIRAPVYLGSPPS---GKPKSLPTNSFVGCLKNFQLDSKPL--YTPSSSFGVSSC 3094
Query: 2886 Y-AVAQEGTYFDGSGYAALVKEGYKVQSDVNITLEFRTSSQNGVLLGISTAKVDAIGLEL 2944
++G YF G ++ + + + R S G+L+ I + + + L
Sbjct: 3095 LGGPLEKGIYFSEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYL 3154
Query: 2945 VDGKVLFHVNNGAGRITAAYEPKTATVLCDGKWHTLQANKSKH--RITLIVDGNAVGAES 3002
GKV +++GAG + + PK + LCDG+WH++ +H + L D + +
Sbjct: 3155 EAGKVTASMDSGAGGTSTSVTPKQS--LCDGQWHSVAVTIKQHILHLELDTDSSYTAGQI 3212
Query: 3003 PHTQSTSVDTNNPIYVGGYPAGVKQKCLRSQTSFRGCLRKLALIKSPQVQSFDFSRAFEL 3062
P ++ T P+++GG PA + + SF GCLR + + P + A E+
Sbjct: 3213 PFPPAS---TQEPLHLGGAPANLTTLRIPVWKSFFGCLRNIHVNHIP----VPVTEALEV 3265
Query: 3063 HG-VFLHSCP 3071
G V L+ CP
Sbjct: 3266 QGPVSLNGCP 3275
Score = 456 bits (1172), Expect = e-127
Identities = 242/569 (42%), Positives = 318/569 (55%), Gaps = 76/569 (13%)
Query: 6 LLVLLLCVAAQC----RQRG------LFPAILNLASNAHISTNATCGEKGP-------EM 48
LL+L+L V C R G L P NLA A I ATCGE+GP E+
Sbjct: 21 LLLLVLRVLPACGATARDPGAAAGLSLHPTYFNLAEAARIWATATCGERGPGEGRPQPEL 80
Query: 49 FCKLVEHVP----GRPVRNPQCRICDGNSANPRERHPISHAIDGTNNWWQSPSIQNGREY 104
+CKLV G ++ C C NS +PR+ HP+++AIDG+ WWQSP + +G +Y
Sbjct: 81 YCKLVGGPTAPGSGHTIQGQFCDYC--NSEDPRKAHPVTNAIDGSERWWQSPPLSSGTQY 138
Query: 105 HWVTITLDLRQVFQVAYVIIKAANAPRPGNWILERSLD-GTTFSPWQYYAVSDSECLSRY 163
+ V +TLDL Q+F VAY++IK AN+PRP W+LERS+D G+T+SPWQY+A S +CL +
Sbjct: 139 NRVNLTLDLGQLFHVAYILIKFANSPRPDLWVLERSVDFGSTYSPWQYFAHSKVDCLKEF 198
Query: 164 NITPRRGPPTYRADDEVICTSYYSRLVPLEHGEIHTSLINGRPSADDL--SPKLLEFTSA 221
R DD+V+C + YSR+VPLE+GE+ SLINGRP A + S L EFT A
Sbjct: 199 G---REANMAVTRDDDVLCVTEYSRIVPLENGEVVVSLINGRPGAKNFTFSHTLREFTKA 255
Query: 222 RYIRLRLQRIRTLNADLMTLSHREPKELDPIVTRRYYYSIKDISVGGMCICYGHASSCPW 281
IRLR R TL L++ + R DP VTRRYYYSIKDIS+GG C+C GHA C
Sbjct: 256 TNIRLRFLRTNTLLGHLISKAQR-----DPTVTRRYYYSIKDISIGGQCVCNGHAEVCNI 310
Query: 282 DETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDES 341
+ K +C+C+H+TCGE+C+RCC GY+Q+ WRP + CEACNCH A +CYYD
Sbjct: 311 NNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPD 370
Query: 342 VAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDP 401
V +Q+ SLNT G + GGGVCINC NT G+NCE C GYYRP+ V + C PC+CDP
Sbjct: 371 VERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDP 430
Query: 402 VGSLSSVCIKDDLHSD-LHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYPTCVSCGCNPVG 460
H+D G G+C CK + G+ C++C +GY ++P C+ PV
Sbjct: 431 E------------HADGCEQGS--GRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVS 476
Query: 461 SASDE----------------------PCTGPCVCKENVEGKACDRCKPGFYNLKEKNPR 498
+ S E G C+C+ VEG CD C+ GFY+
Sbjct: 477 TPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFPI---- 532
Query: 499 GCSECFCFGVSDVCSSLSWPVGQVNSMSG 527
C C+C + S GQ G
Sbjct: 533 -CQACWCSALGSYQMPCSSVTGQCECRPG 560
Score = 330 bits (847), Expect = 1e-89
Identities = 204/606 (33%), Positives = 292/606 (48%), Gaps = 75/606 (12%)
Query: 289 QCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKS 348
QC C+ N G C RC G++ P C+ C+C + +
Sbjct: 1284 QCPCQPNVIGRQCTRCATGHYGFP----------RCKPCSCGRRLCE------------- 1320
Query: 349 LNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSV 408
GQ R C T+ CE C H S + C CNC G++ +
Sbjct: 1321 -EMTGQCR-------CPPRTVRPQCEVC-----ETHSFSFHPMAGCEGCNCSRRGTIEAA 1367
Query: 409 CIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYPTCVSCGCNPVGSASD--EP 466
+ D S GQC CK TG +CDRC G+ +P CV C CN G+ +P
Sbjct: 1368 MPECDRDS--------GQCRCKPRITGRQCDRCASGFYRFPECVPCNCNRDGTEPGVCDP 1419
Query: 467 CTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFCFGVSDVCSSLSWPVGQVNSMS 526
TG C+CKENVEG C+ C+ G ++L N +GC+ CFCFGV++ C S + M
Sbjct: 1420 GTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFCFGVNNQCHSSHKRRTKFVDML 1479
Query: 527 GWLVTDLISPRKIPSQQDALGGRHQVSINNTAVMQRLAPKYY---WAAPEAYLGNKLTAF 583
GW + + + D + S + A +Q L + W AP +YLG+K++++
Sbjct: 1480 GWHL-------ETADRVDIPVSFNPGSNSMVADLQELPATIHSASWVAPTSYLGDKVSSY 1532
Query: 584 GGFLKYTV-SYDIPVETVDSNLMSHADVIIKGNGLTLSTQAEGLSLQPYEEYLNVVRLVP 642
GG+L Y S+ +P + V L DV + G +++ + E + +P + V +V
Sbjct: 1533 GGYLTYQAKSFGLPGDMV--LLEKKPDVQLTGQHMSIIYE-ETNTPRPDRLHHGRVHVVE 1589
Query: 643 ENFQDFHSKRQIDRDQLMTVLANVTHLLIRANYNSAKMALYRLESVSLDIASSNAIDLVV 702
NF+ S+ + R++LMTVL+ + + I+ Y + L L V L+ AS +
Sbjct: 1590 GNFRHASSRAPVSREELMTVLSRLADVRIQGLYFTETQRL-TLSEVGLEEASDTGSGRIA 1648
Query: 703 AADVEHCECPQGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAAEC-NVHGVCIACA 761
A VE C CP Y G SC+ C GYYR L+ G C PC C+GH+ +C + G+C+ C
Sbjct: 1649 LA-VEICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQ 1707
Query: 762 HNTTGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAP 821
HNT G HCE+C G+YG G C+ C CP T N+F+ C +N GD V C C
Sbjct: 1708 HNTAGEHCERCQEGYYG---NAVHGSCRACPCPHT---NSFATGCVVNGGD-VRCS-CKA 1759
Query: 822 GYSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAH 881
GY+G CERCA GY+GNP G SC PC C+ N + G C +TG+C+ D +
Sbjct: 1760 GYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSN---GQLGSCHPLTGDCIN-QEPKDSSP 1815
Query: 882 CERCAD 887
E C D
Sbjct: 1816 AEECDD 1821
Score = 227 bits (579), Expect = 1e-58
Identities = 142/454 (31%), Positives = 193/454 (42%), Gaps = 77/454 (16%)
Query: 727 YYRVDGILFGGICQPCECHGHAAECNVHG----VCIACAHNTTGVHCEQCLPGFYGEPSR 782
YY + I GG C C+GHA CN++ C H+T G C++C G+ R
Sbjct: 287 YYSIKDISIGG---QCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGY--NQRR 341
Query: 783 GTPG------DCQPCACPLTIASNNFSPTCHLNDGD---------EVVCDWCAPGYSGAW 827
P +C+ C C ++ + P VC C +G
Sbjct: 342 WRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVN 401
Query: 828 CERCADGYY---GNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCER 884
CE+CA GYY G P + C+PC C DP A C+ +G C C N G +CE+
Sbjct: 402 CEQCAKGYYRPYGVPVDAPDGCIPCSC----DPEHADGCEQGSGRC-HCKPNFHGDNCEK 456
Query: 885 CADGFYG-----------------DAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNV 927
CA G+Y + A + + C+C+++G +C G C C+P V
Sbjct: 457 CAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAH-GRCLCRPGV 515
Query: 928 TGQQCDQCLHGYYGLDSGHGCRPCNCSVAGSVSDGCTD-EGQCHCVPGVAGKRCDRCAHG 986
G +CD C G+Y C+ C CS GS C+ GQC C PGV G+RCDRC G
Sbjct: 516 EGPRCDTCRSGFYSFPI---CQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSG 572
Query: 987 FYAYQ--DGSCTPCDCPHTQNTCDPETGECVCPPHTQGVKCEECEDGHWGYDAE--VGCQ 1042
Y + GS + CD T N+ G C C H +G C C+ +W D E GC
Sbjct: 573 AYDFPHCQGSSSACDPAGTINS---NLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCS 629
Query: 1043 ACNCSLVGSTHH--RCDVVTGHCQCKSKFGGRACDQCSLGY-----RDFPDCVPCDCDLR 1095
C C G+ C G C CKS GG +CD C GY ++ C C CD+
Sbjct: 630 ECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIG 689
Query: 1096 GTSGDACNLEQGLCGCVEETGACPCKENVFGPQC 1129
G C+ +G C C+E+V G C
Sbjct: 690 GALSSMCS---------GPSGVCQCREHVVGKVC 714
Score = 217 bits (552), Expect = 2e-55
Identities = 140/431 (32%), Positives = 182/431 (42%), Gaps = 77/431 (17%)
Query: 709 CECPQGYTGTSCESCLSGY----YRVDGILFGGICQPCECHGHAAECNVH---------- 754
CEC G +C+ C +GY +R C+ C CHGHA+ C
Sbjct: 319 CECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASL 378
Query: 755 ---------GVCIACAHNTTGVHCEQCLPGF---YGEPSRGTPGDCQPCACPLTIAS--N 800
GVCI C HNT GV+CEQC G+ YG P P C PC+C A
Sbjct: 379 NTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPV-DAPDGCIPCSCDPEHADGCE 437
Query: 801 NFSPTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNP-----------TVPGESCVPC 849
S CH C P + G CE+CA GYY P T E V
Sbjct: 438 QGSGRCH-----------CKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAG 486
Query: 850 D---CSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCADGFYGDAVTAKNCRACECHV 906
D C N++ CD+ G CL C +G C+ C GFY + C+AC C
Sbjct: 487 DIKGCDCNLEGVLPEICDA-HGRCL-CRPGVEGPRCDTCRSGFYSFPI----CQACWCSA 540
Query: 907 KGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLDSGHGCRPCNCSVAGSVSDGCTDE 966
GS+ C TG C+C+P VTGQ+CD+CL G Y G C AG+++ ++
Sbjct: 541 LGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSA-CDPAGTIN---SNL 596
Query: 967 GQCHCVPGVAGKRCDRCAHGFY---AYQDGSCTPCDCPHTQNT------CDPETGECVCP 1017
G C C V G C RC ++ C+ C C H T C G+C C
Sbjct: 597 GYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKC-HKAGTVSGTGECRQGDGDCHCK 655
Query: 1018 PHTQGVKCEECEDGHWGYDAE--VGCQACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACD 1075
H G C+ CEDG++ + GCQ C C + G+ C +G CQC+ G+ C
Sbjct: 656 SHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQ 715
Query: 1076 QCSLGYRDFPD 1086
+ Y FPD
Sbjct: 716 RPENNYY-FPD 725
Score = 191 bits (485), Expect = 1e-47
Identities = 128/421 (30%), Positives = 174/421 (41%), Gaps = 73/421 (17%)
Query: 791 CACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNPTVPG-----ES 845
C C N + C++N+ +++ C G C+RC GY P
Sbjct: 299 CVC------NGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHE 352
Query: 846 CVPCDCSGNV-----DPSEAGHCDSVT--------GECLKCLGNTDGAHCERCADGFY-- 890
C C+C G+ DP S+ G C+ C NT G +CE+CA G+Y
Sbjct: 353 CEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRP 412
Query: 891 -GDAVTAKN-CRACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGL------ 942
G V A + C C C + H+ C +G C CKPN G C++C GYY
Sbjct: 413 YGVPVDAPDGCIPCSCDPE--HADGCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRI 470
Query: 943 -----------DSGHG-CRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCDRCAHGFYAY 990
D G + C+C++ G + + C G+C C PGV G RCD C GFY++
Sbjct: 471 PIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSF 530
Query: 991 QDGSCTPCDCPHT---QNTCDPETGECVCPPHTQGVKCEECEDGHWGYDAEVGCQACNCS 1047
C C C Q C TG+C C P G +C+ C G + + G + C
Sbjct: 531 P--ICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSA-CD 587
Query: 1048 LVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGY----RDFPD-CVPCDCDLRGTSGDAC 1102
G+ + G+CQCK G C +C L Y ++ P C C C GT
Sbjct: 588 PAGTINSNL----GYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTG 643
Query: 1103 NLEQGLCGCVEETGACPCKENVFGPQCNECREGTFALRADNPLGCSPCFC---SGLSHLC 1159
QG G C CK +V G C+ C +G FAL N GC C C LS +C
Sbjct: 644 ECRQG-------DGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMC 696
Query: 1160 S 1160
S
Sbjct: 697 S 697
Score = 125 bits (314), Expect = 6e-28
Identities = 67/208 (32%), Positives = 91/208 (43%), Gaps = 22/208 (10%)
Query: 897 KNCRACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLDSGHGCRPCNCSVA 956
K CECH G+ C E G C C+PNV G+QC +C G+YG C+PC+C
Sbjct: 1261 KGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPR---CKPCSC--G 1315
Query: 957 GSVSDGCTDEGQCHCVPGVAGKRCDRC-AHGFYAYQDGSCTPCDCPH------TQNTCDP 1009
+ + T GQC C P +C+ C H F + C C+C CD
Sbjct: 1316 RRLCEEMT--GQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDR 1373
Query: 1010 ETGECVCPPHTQGVKCEECEDGHWGYDAEVGCQACNCSLVGSTHHRCDVVTGHCQCKSKF 1069
++G+C C P G +C+ C G + + C CNC+ G+ CD TG C CK
Sbjct: 1374 DSGQCRCKPRITGRQCDRCASGFYRFPE---CVPCNCNRDGTEPGVCDPGTGACLCKENV 1430
Query: 1070 GGRACDQCSLGY-----RDFPDCVPCDC 1092
G C+ C G + C C C
Sbjct: 1431 EGTECNVCREGSFHLDPANLKGCTSCFC 1458
Score = 121 bits (303), Expect = 1e-26
Identities = 61/161 (37%), Positives = 86/161 (53%), Gaps = 18/161 (11%)
Query: 819 CAPGYSGAWCERCADGYY-GNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNT 877
C P Y+G C+ C+ GYY + + CVPC+C+G+ + C +G C+ C NT
Sbjct: 1656 CPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGH-----SNQCQDGSGICVNCQHNT 1710
Query: 878 DGAHCERCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETG--LCDCKPNVTGQQCDQC 935
G HCERC +G+YG+AV +CRAC C S + C + G C CK TG QC++C
Sbjct: 1711 AGEHCERCQEGYYGNAVHG-SCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERC 1769
Query: 936 LHGYYGLDS--GHGCRPCNCSVAGSVSDGCTDEGQCHCVPG 974
GY+G G C+PC+C+ G + G CH + G
Sbjct: 1770 APGYFGNPQKFGGSCQPCSCNSNGQL-------GSCHPLTG 1803
Score = 115 bits (289), Expect = 5e-25
Identities = 72/195 (36%), Positives = 92/195 (47%), Gaps = 34/195 (17%)
Query: 1364 CPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAP--CVPCSCN-NHSDTCDPNTGKCL 1420
C T G +C+ CA GY+R P G P+ AP C+PCSC+ H+D C+ +G+C
Sbjct: 393 CQHNTAGVNCEQCAKGYYR---PYGV-----PVDAPDGCIPCSCDPEHADGCEQGSGRC- 443
Query: 1421 NCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPT--------CVLEGDH 1472
+C N GD+C+ C GYY + P S P+S P C LEG
Sbjct: 444 HCKPNFHGDNCEKCAIGYYN----FPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVL 499
Query: 1473 DFRCDA-----CLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQ 1527
CDA C G EG C+ C S +Y P CQ C C+ GS C +GQ
Sbjct: 500 PEICDAHGRCLCRPGVEGPRCDTCRSGFYSFP-----ICQACWCSALGSYQMPCSSVTGQ 554
Query: 1528 CVCRLGASGLRCDEC 1542
C CR G +G RCD C
Sbjct: 555 CECRPGVTGQRCDRC 569
Score = 110 bits (276), Expect = 2e-23
Identities = 97/379 (25%), Positives = 137/379 (36%), Gaps = 97/379 (25%)
Query: 662 VLANVTHLLIRANYNSAKMALYRLESVSLDIASSNAIDLVVAADVEH----------CEC 711
V N H N YR V +D + + D EH C C
Sbjct: 389 VCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGC---IPCSCDPEHADGCEQGSGRCHC 445
Query: 712 PQGYTGTSCESCLSGYYRVDGIL---------------FGGICQPCECH--GHAAE-CNV 753
+ G +CE C GYY L G + C+C+ G E C+
Sbjct: 446 KPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDA 505
Query: 754 HGVCIACAHNTTGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDE 813
HG C+ C G C+ C GFY P CQ C C A ++ C G
Sbjct: 506 HGRCL-CRPGVEGPRCDTCRSGFYSFPI------CQACWCS---ALGSYQMPCSSVTGQ- 554
Query: 814 VVCDWCAPGYSGAWCERCADGYYGNPTVPGES--CVP----------CDCSGNVD----- 856
C+ C PG +G C+RC G Y P G S C P C C +V+
Sbjct: 555 --CE-CRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNLGYCQCKLHVEGPTCS 611
Query: 857 -------------PSEAGHCD-------SVTGECLK------CLGNTDGAHCERCADGFY 890
PS C S TGEC + C + G C+ C DG++
Sbjct: 612 RCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYF 671
Query: 891 G-DAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLDSGHGCR 949
+ C+ C+C + G+ S++C +G+C C+ +V G+ C + + YY D H
Sbjct: 672 ALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQRPENNYYFPDLHH--- 728
Query: 950 PCNCSVAGSVSDGCTDEGQ 968
+ + DG T G+
Sbjct: 729 -----MKYEIEDGSTPNGR 742
Score = 107 bits (268), Expect = 1e-22
Identities = 55/161 (34%), Positives = 76/161 (47%), Gaps = 10/161 (6%)
Query: 879 GAHCERCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLC-DCKPNVTGQQCDQCLH 937
G C+ C+ G+Y D R C+ G HS C +G+C +C+ N G+ C++C
Sbjct: 1662 GDSCQGCSPGYYRDHKGLYTGRCVPCNCNG-HSNQCQDGSGICVNCQHNTAGEHCERCQE 1720
Query: 938 GYYGLDSGHGCRPCNCSVAGSVSDGCTDEG---QCHCVPGVAGKRCDRCAHGFYAYQD-- 992
GYYG CR C C S + GC G +C C G G +C+RCA G++
Sbjct: 1721 GYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKF 1780
Query: 993 -GSCTPCDCPHT--QNTCDPETGECVCPPHTQGVKCEECED 1030
GSC PC C +C P TG+C+ EEC+D
Sbjct: 1781 GGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDD 1821
Score = 107 bits (267), Expect = 2e-22
Identities = 69/220 (31%), Positives = 91/220 (41%), Gaps = 33/220 (15%)
Query: 741 PCECHGHAA---ECNVHGVCIACAHNTTGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTI 797
PCECH A C+ G C N G C +C G YG P C+PC+C +
Sbjct: 1265 PCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPR------CKPCSCGRRL 1318
Query: 798 ASNNFSPTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNPTVPGESCVPCDCS--GNV 855
+ C C P CE C + + G C C+CS G +
Sbjct: 1319 CEE-MTGQCR-----------CPPRTVRPQCEVCETHSFSFHPMAG--CEGCNCSRRGTI 1364
Query: 856 DPSEAGHCDSVTGECLKCLGNTDGAHCERCADGFYGDAVTAKNCRACECHVKGSHSAVCH 915
+ + CD +G+C +C G C+RCA GFY C C C+ G+ VC
Sbjct: 1365 EAAMP-ECDRDSGQC-RCKPRITGRQCDRCASGFY----RFPECVPCNCNRDGTEPGVCD 1418
Query: 916 LETGLCDCKPNVTGQQCDQCLHGYYGLDSGH--GCRPCNC 953
TG C CK NV G +C+ C G + LD + GC C C
Sbjct: 1419 PGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFC 1458
Score = 98.6 bits (244), Expect = 8e-20
Identities = 63/179 (35%), Positives = 81/179 (45%), Gaps = 22/179 (12%)
Query: 916 LETGLCDCKPNVTGQQCDQCLHGYY----GLDSGHGCRPCNCSVAGSVSDGCTD-EGQC- 969
L +C C P G C C GYY GL +G C PCNC+ S+ C D G C
Sbjct: 1649 LAVEICACPPAYAGDSCQGCSPGYYRDHKGLYTGR-CVPCNCN---GHSNQCQDGSGICV 1704
Query: 970 HCVPGVAGKRCDRCAHGFYAYQ-DGSCTPCDCPHTQN---TCDPETGE--CVCPPHTQGV 1023
+C AG+ C+RC G+Y GSC C CPHT + C G+ C C G
Sbjct: 1705 NCQHNTAGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGT 1764
Query: 1024 KCEECEDGHWGYDAEVG--CQACNCSLVGSTHHRCDVVTGHC---QCKSKFGGRACDQC 1077
+CE C G++G + G CQ C+C+ G C +TG C + K CD C
Sbjct: 1765 QCERCAPGYFGNPQKFGGSCQPCSCNSNGQL-GSCHPLTGDCINQEPKDSSPAEECDDC 1822
Score = 88.6 bits (218), Expect = 9e-17
Identities = 67/252 (26%), Positives = 90/252 (35%), Gaps = 51/252 (20%)
Query: 1362 CVCPPGTVGFSCQDCAPGYHRGKL-------PAGSDRGPRPLVAPCVPCSCNNHS---DT 1411
C C P G +C+ CA GY+ P + P+ C CN +
Sbjct: 443 CHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEI 502
Query: 1412 CDPNTGKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLE-G 1470
CD + G+CL C G CD C SG+Y A C+ P +S + C G
Sbjct: 503 CDAH-GRCL-CRPGVEGPRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQCECRPG 560
Query: 1471 DHDFRCDACL-------------------------LGY-------EGKHCERCSSSYYGN 1498
RCD CL LGY EG C RC Y+
Sbjct: 561 VTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNLGYCQCKLHVEGPTCSRCKLLYWNL 620
Query: 1499 PQTPGGSCQKCDCNPHGSVHG--DCDRTSGQCVCRLGASGLRCDECEPRHILMETD---- 1552
+ C +C C+ G+V G +C + G C C+ G CD CE + +E
Sbjct: 621 DKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFG 680
Query: 1553 CVSCDDECVGVL 1564
C C + G L
Sbjct: 681 CQGCQCDIGGAL 692
Score = 71.2 bits (173), Expect = 1e-11
Identities = 58/223 (26%), Positives = 80/223 (35%), Gaps = 38/223 (17%)
Query: 1354 EVASLLENCVCPPGTVGFSCQDCAPGYHRG--------------KLPAGSDRGP---RPL 1396
E+ C+C PG G C C G++ ++P S G RP
Sbjct: 501 EICDAHGRCLCRPGVEGPRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQCECRPG 560
Query: 1397 VAP--CVPC--------SCNNHSDTCDP------NTGKCLNCGDNTAGDHCDVCTSGYYG 1440
V C C C S CDP N G C C + G C C Y+
Sbjct: 561 VTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNLGYC-QCKLHVEGPTCSRCKLLYWN 619
Query: 1441 KVTGSASDCALCACPHSPPASFSPTCVLEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQ 1500
+ S C+ C C + S + C +GD D C + + G C+ C Y+ +
Sbjct: 620 LDKENPSGCSECKCHKAGTVSGTGEC-RQGDGDCHCKSHV---GGDSCDTCEDGYFALEK 675
Query: 1501 TPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDECE 1543
+ CQ C C+ G++ C SG C CR G C E
Sbjct: 676 SNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQRPE 718
Score = 68.2 bits (165), Expect = 1e-10
Identities = 46/162 (28%), Positives = 71/162 (43%), Gaps = 25/162 (15%)
Query: 1403 CSCNNHSDTCDPNTGKCL---NCGDNTAGDHCDVCTSGYYGKVTGSAS-----DCALCAC 1454
C CN H++ C+ N + L C +T G+ CD C +GY + A+ +C C C
Sbjct: 299 CVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNC 358
Query: 1455 -PHSPPASFSP-------TCVLEGDH--DFRCDACLLGYEGKHCERCSSSY---YGNPQT 1501
H+ + P + +G + C C G +CE+C+ Y YG P
Sbjct: 359 HGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVD 418
Query: 1502 PGGSCQKCDCNPHGSVHGD-CDRTSGQCVCRLGASGLRCDEC 1542
C C C+P H D C++ SG+C C+ G C++C
Sbjct: 419 APDGCIPCSCDPE---HADGCEQGSGRCHCKPNFHGDNCEKC 457
Score = 44.3 bits (103), Expect = 0.002
Identities = 20/61 (32%), Positives = 26/61 (42%), Gaps = 2/61 (3%)
Query: 454 CGCNPVGSASDE--PCTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFCFGVSDV 511
C C+P G+ P G C C+ NV G+ C RC G Y P C C ++
Sbjct: 1266 CECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPRCKPCSCGRRLCEEMTGQ 1325
Query: 512 C 512
C
Sbjct: 1326 C 1326
Score = 40.4 bits (93), Expect = 0.027
Identities = 27/115 (23%), Positives = 47/115 (40%), Gaps = 22/115 (19%)
Query: 273 YGHASSCPWDETTK----------KLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGN 322
+G +CP T ++C C+ G C RC PGY P + G
Sbjct: 1728 HGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQK-----FGG 1782
Query: 323 TCEACNCHNKAK--DCY--YDESVAKQKKSLNTAGQFRGGGVCINCLQN---TMG 370
+C+ C+C++ + C+ + + ++ K + A + C+ L N TMG
Sbjct: 1783 SCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSCVMTLLNDLATMG 1837
Score = 39.7 bits (91), Expect = 0.046
Identities = 19/69 (27%), Positives = 28/69 (40%), Gaps = 15/69 (21%)
Query: 1493 SSYYGNPQTPGGSCQK---------------CDCNPHGSVHGDCDRTSGQCVCRLGASGL 1537
+S+Y +PQT C+ C+C+P G+ C GQC C+ G
Sbjct: 1235 NSFYLDPQTASRFCKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGR 1294
Query: 1538 RCDECEPRH 1546
+C C H
Sbjct: 1295 QCTRCATGH 1303
>gi|110611156 laminin, gamma 3 precursor [Homo sapiens]
Length = 1575
Score = 597 bits (1538), Expect = e-170
Identities = 378/1071 (35%), Positives = 509/1071 (47%), Gaps = 120/1071 (11%)
Query: 12 CVAAQCRQRGLFPAILNLASNAHISTNATCGEKGPEMFCKLVEHVPGRPVRNPQCRICDG 71
C R + P N A + TCG PE FC V G C+ CD
Sbjct: 25 CYDGAGRPQRCLPVFENAAFGRLAQASHTCGSP-PEDFCPHV----GAAGAGAHCQRCD- 78
Query: 72 NSANPRERHPISHAID----GTNNWWQSPSIQNGREYHW-VTITLDLRQVFQVAYVIIKA 126
+A+P+ H S+ D + WWQSPS+ G +Y V ITL L + +++ YV +K
Sbjct: 79 -AADPQRHHNASYLTDFHSQDESTWWQSPSMAFGVQYPTSVNITLRLGKAYEITYVRLKF 137
Query: 127 ANAPRPGNWILERSLDGTTFSPWQYYAVSDSECLSRYNITPRRGPPTYRADDEVI--CTS 184
+ I +RS + P+Q+Y+ S + R G +DE + CTS
Sbjct: 138 HTSRPESFAIYKRSRADGPWEPYQFYSASCQKTYGR-----PEGQYLRPGEDERVAFCTS 192
Query: 185 YYSRLVPLEHGEIHTSLINGRPSADDL--SPKLLEFTSARYIRLRLQRIRTLNADLMTLS 242
+S + PL G + S + GRPSA + SP L E+ ++ + + L R+ T D+
Sbjct: 193 EFSDISPLSGGNVAFSTLEGRPSAYNFEESPGLQEWVTSTELLISLDRLNTFGDDIFK-- 250
Query: 243 HREPKELDPIVTRRYYYSIKDISVGGMCICYGHASSCPWDETTKKLQCQCEHNTCGESCN 302
DP V + YYY++ D SVGG C C GHAS C D +L C+C+HNT G C
Sbjct: 251 -------DPKVLQSYYYAVSDFSVGGRCKCNGHASECGPD-VAGQLACRCQHNTTGTDCE 302
Query: 303 RCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCI 362
RC P + +PW GT + + C CNC ++++C +D + + GG C
Sbjct: 303 RCLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGH---------GGRCH 353
Query: 363 NCLQNTMGINCETCIDGYYR--PHKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHN 420
+C +T G +CE C + +Y P PC+PC+C GSL C DD
Sbjct: 354 HCRDHTAGPHCERCQENFYHWDPRM-------PCQPCDCQSAGSLHLQC--DDT------ 398
Query: 421 GKQPGQCPCKEGYTGEKCDRCQLGYKDYPT--CVSCGCNPVGSASD-EPCTGPCVCKENV 477
G C CK TG KCDRC G+ C C CNP GS +P +G C CKENV
Sbjct: 399 ----GTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLDTCDPRSGRCPCKENV 454
Query: 478 EGKACDRCKPGFYNLKEKNPRGCSECFCFGVSDVCSSLSWPVGQVNSMSGWLVTDLISPR 537
EG CDRC+PG +NL+ NP GCS CFC+G S VC+S + QV+ +++D
Sbjct: 455 EGNLCDRCRPGTFNLQPHNPAGCSSCFCYGHSKVCASTA--QFQVHH----ILSDFHQGA 508
Query: 538 KIPSQQDALGGRHQVSINNTAVMQRLAPKYYWAAPEAYLGNKLTAFGGFLKYTVSYDIPV 597
+ + G H + V+ + APE +LG++ ++G L T V
Sbjct: 509 EGWWARSVGGSEHPPQWSPNGVLLSPEDEEELTAPEKFLGDQRFSYGQPLILT----FRV 564
Query: 598 ETVDSNLMSHADVIIKGNGLTLSTQAEGLSLQPYEEYLNVVRL---VPENFQD------- 647
DS L + ++G GL LS + LS + V L + E +D
Sbjct: 565 PPGDSPL--PVQLRLEGTGLALSLRHSSLSGPQDAGHPREVELRFHLQETSEDVAPPLPP 622
Query: 648 FHSKRQIDRDQLMTVLANVTHLLIRANYNSAKMALYRLESVSLDIASSNAIDLVVAADVE 707
FH +R +LAN+T L +R + + L V L A A+ VE
Sbjct: 623 FHFQR---------LLANLTSLRLRVSPGPSPAGPVFLTEVRLTSARPGLSP--PASWVE 671
Query: 708 HCECPQGYTGTSCESCLSGYYRVDGILFGG---ICQPCECHGHAAECNVHGVCIACAHNT 764
C CP GYTG CESC GY R + GG C PC C+ H G+C+ C+H+T
Sbjct: 672 ICSCPTGYTGQFCESCAPGYKR--EMPQGGPYASCVPCTCNQHGTCDPNTGICV-CSHHT 728
Query: 765 TGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYS 824
G CE+CLPGFYG P G DCQPC CP S + + EVVC C PG
Sbjct: 729 EGPSCERCLPGFYGNPFAGQADDCQPCPCP------GQSACTTIPESREVVCTHCPPGQR 782
Query: 825 GAWCERCADGYYGNPT---VPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAH 881
G CE C DG++G+P + C C CSGNVDP+ G+CD ++G CL+CL NT G H
Sbjct: 783 GRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDH 842
Query: 882 CERCADGFYGDAVT---AKNCRACECHVKGSHS--AVCHLETGLCDCKPNVTGQQCDQCL 936
CE C +GFYG A+ A C C CH +GS S C TG C C P+VT + C +C
Sbjct: 843 CEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCY 902
Query: 937 HGYYGLDSGHGCRPCNCSVAGSVSDGCTDE-GQCHCVPGVAGKRCDRCAHGFYAYQDGSC 995
G++ L G GCR C C GS D C + GQC C PGV G+ CDRC GF+ + C
Sbjct: 903 PGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGC 962
Query: 996 TPCDCP--HTQNTCDPETGECVCPPHTQGVKCEECEDGHWGYDAEVGCQAC 1044
C C + E G CVC P +G KC+ C D + CQ C
Sbjct: 963 RACRCSPLGAASAQCHENGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQC 1013
Score = 264 bits (675), Expect = 9e-70
Identities = 191/631 (30%), Positives = 274/631 (43%), Gaps = 88/631 (13%)
Query: 944 SGHGCRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCDRCAHGFY--------AYQDGSC 995
+GH C VAG ++ C C G C+RC F A C
Sbjct: 274 NGHASE-CGPDVAGQLA--------CRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHEC 324
Query: 996 TPCDCPHTQNTC--DPET-------GECV-CPPHTQGVKCEECEDGHWGYDAEVGCQACN 1045
PC+C C D E G C C HT G CE C++ + +D + CQ C+
Sbjct: 325 LPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMPCQPCD 384
Query: 1046 CSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGYRDFPD--CVPCDCDLRGTSGDACN 1103
C GS H +CD TG C CK G CD+C G+ + C PC C+ G+
Sbjct: 385 CQSAGSLHLQCDD-TGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGS------ 437
Query: 1104 LEQGLCGCVEETGACPCKENVFGPQCNECREGTFALRADNPLGCSPCFCSGLSHLCSELE 1163
L C +G CPCKENV G C+ CR GTF L+ NP GCS CFC G S +C+
Sbjct: 438 ----LDTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCYGHSKVCASTA 493
Query: 1164 DY----VRTPVTLGSDQPLLRVVSQSNLRGTTEGVYYQAPDFLLDAATVRQHIRAEPFYW 1219
+ + + G++ R V G +E +P+ +L + + + A
Sbjct: 494 QFQVHHILSDFHQGAEGWWARSV------GGSEHPPQWSPNGVLLSPEDEEELTA----- 542
Query: 1220 RLPQQFQGDQLMAYGGKLKYSVAFYSLDGVGTSNFEPQVLIKGGRIRKQVIYMDAPAPEN 1279
P++F GDQ +YG L + G S Q+ ++G + + + P++
Sbjct: 543 --PEKFLGDQRFSYGQPLILTFRV----PPGDSPLPVQLRLEGTGLALSLRHSSLSGPQD 596
Query: 1280 GVRQEQEVAMRENFWKYFNSVSEKPVTREDFMSVLSDIEYILIKASYGQGLQQSRISDIS 1339
+EV +R + + V+ P+ F +L+++ + ++ S G S +
Sbjct: 597 -AGHPREVELRFHLQETSEDVA-PPLPPFHFQRLLANLTSLRLRVSPG----PSPAGPVF 650
Query: 1340 MEVGRKAEKLHPEEEVASLLENCVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAP 1399
+ R AS +E C CP G G C+ CAPGY R ++P G GP A
Sbjct: 651 LTEVRLTSARPGLSPPASWVEICSCPTGYTGQFCESCAPGYKR-EMPQG---GP---YAS 703
Query: 1400 CVPCSCNNHSDTCDPNTGKCLNCGDNTAGDHCDVCTSGYYGK-VTGSASDCALCACPHSP 1458
CVPC+CN H TCDPNTG C+ C +T G C+ C G+YG G A DC C CP
Sbjct: 704 CVPCTCNQHG-TCDPNTGICV-CSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQS 761
Query: 1459 PASFSPTCVLEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQTPGG---SCQKCDC--NP 1513
+ P + C C G G+ CE C ++G+P G C +C C N
Sbjct: 762 ACTTIPE-----SREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNV 816
Query: 1514 HGSVHGDCDRTSGQCV-CRLGASGLRCDECE 1543
+ G+CD SG C+ C +G C+ C+
Sbjct: 817 DPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQ 847
Score = 194 bits (494), Expect = 9e-49
Identities = 118/361 (32%), Positives = 158/361 (43%), Gaps = 51/361 (14%)
Query: 819 CAPGYSGAWCERCADGYYGNPTVPGE--SCVPCDCSGNVDPSEAGHCDSVTGECLKCLGN 876
C GY+G +CE CA GY G SCVPC C+ + G CD TG C+ C +
Sbjct: 675 CPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCN------QHGTCDPNTGICV-CSHH 727
Query: 877 TDGAHCERCADGFYGD--AVTAKNCRACECHVKGSHSAVCHLETGLCD-CKPNVTGQQCD 933
T+G CERC GFYG+ A A +C+ C C + + + + +C C P G++C+
Sbjct: 728 TEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPGQRGRRCE 787
Query: 934 QCLHGYYGLDSG-----HGCRPCNCSVAGSVSDGCTDE-----GQC-HCVPGVAGKRCDR 982
C G++G G C C CS G+V G C C+ G C+
Sbjct: 788 VCDDGFFGDPLGLFGHPQPCHQCQCS--GNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEH 845
Query: 983 CAHGFYAYQ-----DGSCTPCDCPHTQNT------CDPETGECVCPPHTQGVKCEECEDG 1031
C GFY C PC C H Q + CDP TG+C C PH C C G
Sbjct: 846 CQEGFYGSALAPRPADKCMPCSC-HPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPG 904
Query: 1032 HWGYDAEVGCQACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGYRDF--PDCVP 1089
+ GC++C C +GS +C TG C C+ G+ACD+C LG+ F C
Sbjct: 905 FFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRA 964
Query: 1090 CDCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFALRADNPLGCSP 1149
C C G + C+ E G C C+ G +C+ C + F L AD C
Sbjct: 965 CRCSPLGAASAQCH----------ENGTCVCRPGFEGYKCDRCHD-NFFLTADG-THCQQ 1012
Query: 1150 C 1150
C
Sbjct: 1013 C 1013
Score = 151 bits (381), Expect = 1e-35
Identities = 98/321 (30%), Positives = 131/321 (40%), Gaps = 55/321 (17%)
Query: 869 ECLKCLGNTDGAHCERCADGFYGDAVTA---KNCRACECHVKGSHSAVCHLETGLCDCKP 925
E C G CE CA G+ + +C C C+ G+ C TG+C C
Sbjct: 671 EICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT----CDPNTGICVCSH 726
Query: 926 NVTGQQCDQCLHGYYG---LDSGHGCRPCNC-------SVAGSVSDGCTDEGQCHCVPGV 975
+ G C++CL G+YG C+PC C ++ S CT HC PG
Sbjct: 727 HTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCT-----HCPPGQ 781
Query: 976 AGKRCDRCAHGFYAYQDG------SCTPCDC-----PHTQNTCDPETGECV-CPPHTQGV 1023
G+RC+ C GF+ G C C C P+ CDP +G C+ C +T G
Sbjct: 782 RGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGD 841
Query: 1024 KCEECEDGHWGYDAEVG----CQACNCSLVGSTHHR--CDVVTGHCQCKSKFGGRACDQC 1077
CE C++G +G C C+C GS + CD VTG C C R C +C
Sbjct: 842 HCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRC 901
Query: 1078 SLGYRDFPD---CVPCDCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNECRE 1134
G+ D C C C G+ D C+ +TG C C+ V G C+ C+
Sbjct: 902 YPGFFDLQPGRGCRSCKCHPLGSQEDQCH---------PKTGQCTCRPGVTGQACDRCQL 952
Query: 1135 GTFALRADNPLGCSPCFCSGL 1155
G F GC C CS L
Sbjct: 953 GFFGFSIK---GCRACRCSPL 970
Score = 135 bits (341), Expect = 5e-31
Identities = 73/222 (32%), Positives = 98/222 (44%), Gaps = 34/222 (15%)
Query: 849 CDCSGNVDPSEAGHCDSVTGE-CLKCLGNTDGAHCERCADGFY------GDAVTAKNCRA 901
C C+G+ SE G V G+ +C NT G CERC F G A A C
Sbjct: 271 CKCNGHA--SECG--PDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLP 326
Query: 902 CECHVKGS-------------HSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLDSGHGC 948
C C + H CH C+ + G C++C +Y D C
Sbjct: 327 CNCSGRSEECTFDRELFRSTGHGGRCH------HCRDHTAGPHCERCQENFYHWDPRMPC 380
Query: 949 RPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCDRCAHGFYAYQDGSCTPCDC--PHTQNT 1006
+PC+C AGS+ C D G C C P V G +CDRC GF++ +G C PC C + +T
Sbjct: 381 QPCDCQSAGSLHLQCDDTGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLDT 440
Query: 1007 CDPETGECVCPPHTQGVKCEECEDGHWGYDAE--VGCQACNC 1046
CDP +G C C + +G C+ C G + GC +C C
Sbjct: 441 CDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFC 482
Score = 116 bits (291), Expect = 3e-25
Identities = 65/188 (34%), Positives = 86/188 (45%), Gaps = 21/188 (11%)
Query: 1364 CPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSD-----TCDPNTGK 1418
CPPG G C+ C G+ P G P+P C C C+ + D CDP +G
Sbjct: 777 CPPGQRGRRCEVCDDGFFGD--PLGLFGHPQP----CHQCQCSGNVDPNAVGNCDPLSGH 830
Query: 1419 CLNCGDNTAGDHCDVCTSGYYGKVTGS--ASDCALCAC-PHSPPASFSPTCVLEGDHDFR 1475
CL C NT GDHC+ C G+YG A C C+C P + P + G +
Sbjct: 831 CLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTG----Q 886
Query: 1476 CDACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGAS 1535
C +CL + C RC ++ PG C+ C C+P GS C +GQC CR G +
Sbjct: 887 C-SCLPHVTARDCSRCYPGFFD--LQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVT 943
Query: 1536 GLRCDECE 1543
G CD C+
Sbjct: 944 GQACDRCQ 951
Score = 96.7 bits (239), Expect = 3e-19
Identities = 58/172 (33%), Positives = 74/172 (43%), Gaps = 14/172 (8%)
Query: 1403 CSCNNHSDTCDPNTGKCL--NCGDNTAGDHCDVCTSGYYGK-----VTGSASDCALCACP 1455
C CN H+ C P+ L C NT G C+ C + + +A +C C C
Sbjct: 271 CKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCS 330
Query: 1456 -HSPPASFSPTCVLEGDHDFRCDACLLGYEGKHCERCSSSYY-GNPQTPGGSCQKCDCNP 1513
S +F H RC C G HCERC ++Y +P+ P CQ CDC
Sbjct: 331 GRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMP---CQPCDCQS 387
Query: 1514 HGSVHGDCDRTSGQCVCRLGASGLRCDECEPR-HILMETDCVSCDDECVGVL 1564
GS+H CD T G C C+ +G +CD C P H L E C C G L
Sbjct: 388 AGSLHLQCDDT-GTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSL 438
Score = 95.1 bits (235), Expect = 9e-19
Identities = 60/213 (28%), Positives = 84/213 (39%), Gaps = 40/213 (18%)
Query: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCD-------- 1413
C C T G C+ C P + RG C+PC+C+ S+ C
Sbjct: 290 CRCQHNTTGTDCERCLPFFQDRPWA----RGTAEAAHECLPCNCSGRSEECTFDRELFRS 345
Query: 1414 -PNTGKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGDH 1472
+ G+C +C D+TAG HC+ C +Y C C C + G
Sbjct: 346 TGHGGRCHHCRDHTAGPHCERCQENFYH--WDPRMPCQPCDCQSA------------GSL 391
Query: 1473 DFRCD-----ACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQ 1527
+CD AC G C+RC ++ + G C+ C CNP GS+ CD SG+
Sbjct: 392 HLQCDDTGTCACKPTVTGWKCDRCLPGFHSLSE---GGCRPCTCNPAGSLD-TCDPRSGR 447
Query: 1528 CVCRLGASGLRCDECEPRHILME----TDCVSC 1556
C C+ G CD C P ++ C SC
Sbjct: 448 CPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSC 480
Score = 67.0 bits (162), Expect = 3e-10
Identities = 50/164 (30%), Positives = 65/164 (39%), Gaps = 33/164 (20%)
Query: 1350 HPEEEVASLLE------NCVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPC 1403
HP+ V+ + C C P C C PG+ L G RG C C
Sbjct: 869 HPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFF--DLQPG--RG-------CRSC 917
Query: 1404 SCN---NHSDTCDPNTGKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPA 1460
C+ + D C P TG+C C G CD C G++G S C C C A
Sbjct: 918 KCHPLGSQEDQCHPKTGQC-TCRPGVTGQACDRCQLGFFGF---SIKGCRACRCSPLGAA 973
Query: 1461 SF----SPTCVLE-GDHDFRCDAC----LLGYEGKHCERCSSSY 1495
S + TCV G ++CD C L +G HC++C S Y
Sbjct: 974 SAQCHENGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQCPSCY 1017
Score = 58.5 bits (140), Expect = 1e-07
Identities = 34/90 (37%), Positives = 41/90 (45%), Gaps = 17/90 (18%)
Query: 1457 SPPASFSPTCVLEGDHDFRCDACLLGYEGKHCERCSSSYYGN-PQT-PGGSCQKCDCNPH 1514
SPPAS+ C +C GY G+ CE C+ Y PQ P SC C CN H
Sbjct: 664 SPPASWVEIC-----------SCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQH 712
Query: 1515 GSVHGDCDRTSGQCVCRLGASGLRCDECEP 1544
G+ CD +G CVC G C+ C P
Sbjct: 713 GT----CDPNTGICVCSHHTEGPSCERCLP 738
Score = 40.4 bits (93), Expect = 0.027
Identities = 32/112 (28%), Positives = 41/112 (36%), Gaps = 11/112 (9%)
Query: 1337 DISMEVGRKAEKLHP----EEEVASLLENCVCPPGTVGFSCQDCAPGYHRGKLPAGSDRG 1392
D+ G ++ K HP E++ C C PG G +C C G+ +
Sbjct: 907 DLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRACR 966
Query: 1393 PRPLVAPCVPCSCNNHSDTCDPNTG--KCLNCGDN----TAGDHCDVCTSGY 1438
PL A C N + C P KC C DN G HC C S Y
Sbjct: 967 CSPLGAASAQCH-ENGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQCPSCY 1017
>gi|21264602 laminin alpha 5 [Homo sapiens]
Length = 3695
Score = 513 bits (1320), Expect = e-144
Identities = 282/752 (37%), Positives = 386/752 (51%), Gaps = 66/752 (8%)
Query: 289 QCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKS 348
QC C + G C+RC GY P C C+C A+ C DE
Sbjct: 1456 QCPCHAHVIGRDCSRCATGYWGFP----------NCRPCDCG--ARLC--DELT------ 1495
Query: 349 LNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSV 408
G CI C T+ +C C +P + C CNC G
Sbjct: 1496 ----------GQCI-CPPRTIPPDCLLC-----QPQTFGCHPLVGCEECNCSGPGIQELT 1539
Query: 409 CIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYPTCVSCGCNPVGSASD--EP 466
D S GQC C+ TG +CD C G+ YP C C C+ G+A +P
Sbjct: 1540 DPTCDTDS--------GQCKCRPNVTGRRCDTCSPGFHGYPRCRPCDCHEAGTAPGVCDP 1591
Query: 467 CTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFCFGVSDVCSSLSWPVGQVNSMS 526
TG C CKENV+G CD+C G ++L NP+GC+ CFCFG ++ C S S+ + M
Sbjct: 1592 LTGQCYCKENVQGPKCDQCSLGTFSLDAANPKGCTRCFCFGATERCRSSSYTRQEFVDME 1651
Query: 527 GWLVTDLISPRKIPSQQDALGGRHQVSINNTAVMQRLA---PKYYWAAPEAYLGNKLTAF 583
GW+ L+S + + G + + V + + P+ YW AP +YLG++++++
Sbjct: 1652 GWV---LLSTDRQVVPHERQPGTEMLRADLRHVPEAVPEAFPELYWQAPPSYLGDRVSSY 1708
Query: 584 GGFLKYTVSYDIPVETVDSNLMSHADVIIKGNGLTLSTQAEGLSLQPYEEYLNVVRLVPE 643
GG L+Y + + V + S DV+++GN +++ T E P + ++LV
Sbjct: 1709 GGTLRYELHSETQRGDVFVPMESRPDVVLQGNQMSI-TFLEPAYPTPGHVHRGQLQLVEG 1767
Query: 644 NFQDFHSKRQIDRDQLMTVLANVTHLLIRANYNSAKMALYRLESVSLDIASSNAIDLVVA 703
NF+ ++ + R++LM VLA++ L IRA ++ A++ L V+L++AS A +A
Sbjct: 1768 NFRHTETRNTVSREELMMVLASLEQLQIRALFSQISSAVF-LRRVALEVASP-AGQGALA 1825
Query: 704 ADVEHCECPQGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAAECNV-HGVCIACAH 762
++VE C CP Y G SC+ C G+YR LF G C PC+CHGH+ C GVC+ C H
Sbjct: 1826 SNVELCLCPASYRGDSCQECAPGFYRDVKGLFLGRCVPCQCHGHSDRCLPGSGVCVDCQH 1885
Query: 763 NTTGVHCEQCLPGFYGEPSRGTPG-DCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAP 821
NT G HCE+C GF SR P C C CPL++ SNNF+ C L G C C P
Sbjct: 1886 NTEGAHCERCQAGFVS--SRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGG-RTQC-LCKP 1941
Query: 822 GYSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEA-GHCDSVTGECLKCLGNTDGA 880
GY+GA CERCA G++GNP V G SC PCDCSGN DP+ CD +TG C CL +T G
Sbjct: 1942 GYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGP 2001
Query: 881 HCERCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYY 940
CE CA GFYG+A+ NC C+C G+ + C +G C CK VTG++CD+C G++
Sbjct: 2002 RCEICAPGFYGNALLPGNCTRCDCTPCGTEA--CDPHSGHCLCKAGVTGRRCDRCQEGHF 2059
Query: 941 GLDSGHGCRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCDRCAHGFYAYQDGSCTPCDC 1000
G D GCRPC C A S+ GQCHC PG G +C CA G++ + C C C
Sbjct: 2060 GFDGCGGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLPEQGCRRCQC 2119
Query: 1001 PHTQNTCDPETGECVCPPHTQGVKCEECEDGH 1032
P CDP TG C CPP G +C+ C H
Sbjct: 2120 P--GGRCDPHTGRCNCPPGLSGERCDTCSQQH 2149
Score = 451 bits (1160), Expect = e-126
Identities = 241/562 (42%), Positives = 321/562 (57%), Gaps = 90/562 (16%)
Query: 5 VLLVLLLCVAAQCRQRG-----LFPAILNLASNAHISTNATCGEKGP---------EMFC 50
+L+ L L AA+ R+ L P NLA A I+ +ATCGE+ P +++C
Sbjct: 23 LLVGLALLGAARAREEAGGGFSLHPPYFNLAEGARIAASATCGEEAPARGSPRPTEDLYC 82
Query: 51 KLVEHV-----PGRPVRNPQCRICDGNSANPRERHPISHAIDGTNNWWQSPSIQNGREYH 105
KLV P + +R C IC +AN + HP S+AIDGT WWQSP + G EY+
Sbjct: 83 KLVGGPVAGGDPNQTIRGQYCDIC--TAANSNKAHPASNAIDGTERWWQSPPLSRGLEYN 140
Query: 106 WVTITLDLRQVFQVAYVIIKAANAPRPGNWILERSLD-GTTFSPWQYYAVSDSECLSRYN 164
V +TLDL QVF VAYV+IK AN+PRP W+LERS+D G T+ PWQ++A S +CL R+
Sbjct: 141 EVNVTLDLGQVFHVAYVLIKFANSPRPDLWVLERSMDFGRTYQPWQFFASSKRDCLERF- 199
Query: 165 ITPRRGPPTYRA---DDEVICTSYYSRLVPLEHGEIHTSLINGRPSADDLS--PKLLEFT 219
GP T DD ICT+ YSR+VPLE+GEI SL+NGRP A + S P L EFT
Sbjct: 200 -----GPQTLERITRDDAAICTTEYSRIVPLENGEIVVSLVNGRPGAMNFSYSPLLREFT 254
Query: 220 SARYIRLRLQRIRTLNADLMTLSHREPKELDPIVTRRYYYSIKDISVGGMCICYGHASSC 279
A +RLR R TL LM + R DP VTRRYYYSIKDIS+GG C+C+GHA +C
Sbjct: 255 KATNVRLRFLRTNTLLGHLMGKALR-----DPTVTRRYYYSIKDISIGGRCVCHGHADAC 309
Query: 280 PWDETTK--KLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCY 337
+ T +LQC C+HNTCG +C+RCCPG++QQPW+P T +S N C++CNC+ A DCY
Sbjct: 310 DAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHATDCY 369
Query: 338 YDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPC 397
YD V +++ S + G ++GGGVCI+C +T G+NCE C+ G+YR CR C
Sbjct: 370 YDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRC 429
Query: 398 NCDPVGSLSSVCIKDDLHSDLHNG---KQPGQCPCKEGYTGEKCDRCQLGYKDYPTC--- 451
NC+ SD +G G+C C+ ++GE+CD C G+ +P+C
Sbjct: 430 NCE---------------SDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPT 474
Query: 452 -----------------VSCGCNPVGSASD----EPCTGPCVCKENVEGKACDRCKPGFY 490
V+C C+ G+ + +P G C+CK N +G C+ C PGFY
Sbjct: 475 PSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFY 534
Query: 491 NLKEKNPRGCSECFCF--GVSD 510
GC C C GV+D
Sbjct: 535 G------PGCQPCQCSSPGVAD 550
Score = 365 bits (937), Expect = e-100
Identities = 215/640 (33%), Positives = 315/640 (49%), Gaps = 76/640 (11%)
Query: 946 HGCRPCNCSVAGSVSDGCTD-EGQCHCVPGVAGKRCDRCAHGFYAYQDGSCTPCDCPHTQ 1004
+G RPC C G+ C GQC C V G+ C RCA G++ + + C PCDC
Sbjct: 1433 NGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFPN--CRPCDCG--A 1488
Query: 1005 NTCDPETGECVCPPHTQGVKCEECEDGHWGYDAEVGCQACNCSLVGS---THHRCDVVTG 1061
CD TG+C+CPP T C C+ +G VGC+ CNCS G T CD +G
Sbjct: 1489 RLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSG 1548
Query: 1062 HCQCKSKFGGRACDQCSLGYRDFPDCVPCDCDLRGTSGDACNLEQGLCGCVEETGACPCK 1121
C+C+ GR CD CS G+ +P C PCDC GT+ C+ TG C CK
Sbjct: 1549 QCKCRPNVTGRRCDTCSPGFHGYPRCRPCDCHEAGTAPGVCD---------PLTGQCYCK 1599
Query: 1122 ENVFGPQCNECREGTFALRADNPLGCSPCFCSGLSHLCSELEDYVRTP-------VTLGS 1174
ENV GP+C++C GTF+L A NP GC+ CFC G + C Y R V L +
Sbjct: 1600 ENVQGPKCDQCSLGTFSLDAANPKGCTRCFCFGATERCRS-SSYTRQEFVDMEGWVLLST 1658
Query: 1175 DQPLLRVVSQ-------SNLRGTTEGVYYQAPDFLLDAATVRQHIRAEPFYWRLPQQFQG 1227
D+ ++ Q ++LR E V P+ YW+ P + G
Sbjct: 1659 DRQVVPHERQPGTEMLRADLRHVPEAVPEAFPEL----------------YWQAPPSYLG 1702
Query: 1228 DQLMAYGGKLKYSVAFYSLDGVGTSNFE--PQVLIKGGRIRKQVIYMDAPAPENGVRQEQ 1285
D++ +YGG L+Y + + G E P V+++G ++ + +++ P G
Sbjct: 1703 DRVSSYGGTLRYELHSETQRGDVFVPMESRPDVVLQGNQM--SITFLEPAYPTPGHVHRG 1760
Query: 1286 EVAMRENFWKYFNSVSEKPVTREDFMSVLSDIEYILIKASYGQGLQQSRISDISMEVGRK 1345
++ + E +++ + + V+RE+ M VL+ +E + I+A + Q + +++EV
Sbjct: 1761 QLQLVEGNFRH--TETRNTVSREELMMVLASLEQLQIRALFSQISSAVFLRRVALEVASP 1818
Query: 1346 AEKLHPEEEVASLLENCVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSC 1405
A + +AS +E C+CP G SCQ+CAPG++R R CVPC C
Sbjct: 1819 AG----QGALASNVELCLCPASYRGDSCQECAPGFYRDVKGLFLGR--------CVPCQC 1866
Query: 1406 NNHSDTCDPNTGKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPA-SFSP 1464
+ HSD C P +G C++C NT G HC+ C +G+ ++ C C CP S P+ +F+
Sbjct: 1867 HGHSDRCLPGSGVCVDCQHNTEGAHCERCQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAE 1926
Query: 1465 TCVLEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGS---VHGDC 1521
CVL G +C C GY G CERC+ ++GNP G SCQ CDC+ +G + DC
Sbjct: 1927 GCVLRGGRT-QC-LCKPGYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDC 1984
Query: 1522 DRTSGQC-VCRLGASGLRCDECEP---RHILMETDCVSCD 1557
D +G C C +G RC+ C P + L+ +C CD
Sbjct: 1985 DPLTGACRGCLRHTTGPRCEICAPGFYGNALLPGNCTRCD 2024
Score = 293 bits (750), Expect = 2e-78
Identities = 425/1860 (22%), Positives = 755/1860 (40%), Gaps = 253/1860 (13%)
Query: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDT------CDPN 1415
C+C PG G SC+ CAPG+ L GS C PC C+ + D CDP
Sbjct: 1937 CLCKPGYAGASCERCAPGFFGNPLVLGSS---------CQPCDCSGNGDPNLLFSDCDPL 1987
Query: 1416 TGKCLNCGDNTAGDHCDVCTSGYYGK--VTGSASDCALCACPHSPPASFSPTCVLE-GDH 1472
TG C C +T G C++C G+YG + G+ + C C S C+ + G
Sbjct: 1988 TGACRGCLRHTTGPRCEICAPGFYGNALLPGNCTRCDCTPCGTEACDPHSGHCLCKAGVT 2047
Query: 1473 DFRCDACLLGY------------------EGKHCERCSSSYYGNPQTPGGSCQKC----- 1509
RCD C G+ EG C S + P T G C++C
Sbjct: 2048 GRRCDRCQEGHFGFDGCGGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYW 2107
Query: 1510 -----DCNPHGSVHGDCDRTSGQCVCRLGASGLRCDECEPRH--------ILMETDCVSC 1556
C G CD +G+C C G SG RCD C +H + C C
Sbjct: 2108 GLPEQGCRRCQCPGGRCDPHTGRCNCPPGLSGERCDTCSQQHQVPVPGGPVGHSIHCEVC 2167
Query: 1557 DDECVGVLLNDLDEIGDAVLSLN--LTGI--IPVPYGILSNLENTTKYLQESLLKENMQK 1612
D CV +LL+DL+ G + +++ L GI + + L L + LQ L +
Sbjct: 2168 -DHCVVLLLDDLERAGALLPAIHEQLRGINASSMAWARLHRLNASIADLQSQLRSPLGPR 2226
Query: 1613 DLGKIKLEGVAEETDNLQKKLTRM-------LASTQKVNRATERIFKESQDLAIAIERLQ 1665
+LE + +++ +L + R+ ++ TE ++ L AI +
Sbjct: 2227 HETAQQLEVLEQQSTSLGQDARRLGGQAVGTRDQASQLLAGTEATLGHAKTLLAAIRAVD 2286
Query: 1666 MSITEIMEKTTLNQTLDEDFLLPNSTLQNMQQNGTSLLEI------MQIRDFTQLHQNAT 1719
+++E+M +T L N++ + +Q +L E+ M+ RD A
Sbjct: 2287 RTLSELMSQT-------GHLGLANASAPSGEQLLRTLAEVERLLWEMRARDLGAPQAAAE 2339
Query: 1720 LELKAAEDLLSQIQENYQKPLEELEVLKEAASHVLSKHNNEL-KAAEALVREAEAKMQES 1778
EL AA+ LL+++QE EE + L L++H L EAL R +A +
Sbjct: 2340 AELAAAQRLLARVQEQLSSLWEENQALATQTRDRLAQHEAGLMDLREALNRAVDATREAQ 2399
Query: 1779 NHLLLMVNANLREFSDKKLHVQEEQNLTSELIVQGRGLIDAAAAQTDAVQDALEHLEDHQ 1838
+N+ +E ++ L ++E + + + + + AA +V L L+ +
Sbjct: 2400 E-----LNSRNQERLEEALQRKQELSRDNATL---QATLHAARDTLASVFRLLHSLDQAK 2451
Query: 1839 DKLLLWSAKIRHHIDDLVMHMS----QRNAVDLVYRAEDHAAEFQRLADVLYSGLENIR- 1893
++L +A + L+ M + + LV AE HA + +LA L S + ++
Sbjct: 2452 EELERLAASLDGARTPLLQRMQTFSPAGSKLRLVEAAEAHAQQLGQLALNLSSIILDVNQ 2511
Query: 1894 -NVSLNATSAAYVHYNIQSLIEESEELARDAHRTVTET--SLLSESLVSNGKAAVQRSS- 1949
++ A A+ + I ++ +E+ A A + T +++ + LV + + S+
Sbjct: 2512 DRLTQRAIEASNAYSRILQAVQAAEDAAGQALQQADHTWATVVRQGLVDRAQQLLANSTA 2571
Query: 1950 ---RFLKEGNNLSRKLPGIALELSELRNKTNRFQENAVEITRQTNESLLILRAIPKGIRD 2006
L+E L L AL+ + + + R +++ +E Q +++L +
Sbjct: 2572 LEEAMLQEQQRLG--LVWAALQGARTQLRDVRAKKDQLEAHIQAAQAMLAMDT--DETSK 2627
Query: 2007 KGAKTKELATSASQSAVSTLRDVAGLSQELLNTSASLSRVNTTLRETHQLLQDSTMATLL 2066
K A K +A A +A + + + + + QD A L
Sbjct: 2628 KIAHAKAVAAEAQDTATRVQSQLQAMQENVERWQGQYEGLRG---------QDLGQAVLD 2678
Query: 2067 AGRKVKDVEIQANLLFDRLKPLKMLEEN--------LSRNLSEIKLLISQARKQAASIKV 2118
AG V +E L L L +LE LS ++ ++ LI+QAR A+ +KV
Sbjct: 2679 AGHSVSTLE---KTLPQLLAKLSILENRGVHNASLALSASIGRVRELIAQARGAASKVKV 2735
Query: 2119 AVSAD-RDCIRAYQPQ--ISSTNYNTLTLNVKTQEP-------DNLLFYLGSSTAS-DFL 2167
+ + R ++ P+ Y L ++ EP D + Y+GS A+ D++
Sbjct: 2736 PMKFNGRSGVQLRTPRDLADLAAYTALKFYLQGPEPEPGQGTEDRFVMYMGSRQATGDYM 2795
Query: 2168 AVEMRRGRVAFLWDLGSGSTRLEFPDFPIDDNRWHSIHVARFGNIGSLSV---KEMSSNQ 2224
V +R +V +++ LG + D I + ++ ++ + R G +SV ++M
Sbjct: 2796 GVSLRDKKVHWVYQLGEAGPAVLSIDEDIGE-QFAAVSLDRTLQFGHMSVTVERQMIQET 2854
Query: 2225 KSPTKTSKSPGTANVLDVNNSTLMF-VGGLGGQIKKSPAVKVTHFKGCLGEAFLNGKSIG 2283
K T +PG +L++ +F VGG P ++ ++GC+ LN + +
Sbjct: 2855 KGDT---VAPGAEGLLNLRPDDFVFYVGGYPSTFTPPPLLRFPGYRGCIEMDTLNEEVVS 2911
Query: 2284 LWNYIEREGKC-----RGCFGSSQNEDP----SFHFDGSGYSVVE-KSLPATVTQIIMLF 2333
L+N+ ER + R C S DP + DG+G++ + S +T +
Sbjct: 2912 LYNF-ERTFQLDTAVDRPCARSKSTGDPWLTDGSYLDGTGFARISFDSQISTTKRFEQEL 2970
Query: 2334 NTFSPNGLLLYLGSYGTKDFLSIELFRGRVKVMTDLGSG-----PITLLTDRRYNNGTWY 2388
S +G+L +L FL + + G + ++ D G+G P+ +
Sbjct: 2971 RLVSYSGVLFFLKQ--QSQFLCLAVQEGSLVLLYDFGAGLKKAVPLQPPPPLTSASKAIQ 3028
Query: 2389 KIAFQRNRKQGVLAVIDAYNTSNKETKQGETPGASSDLNRLDKDPIYVGGLPRSRV---V 2445
+RK+ ++ V A S ++ E D Y+GG+P ++ +
Sbjct: 3029 VFLLGGSRKRVLVRVERATVYSVEQDNDLEL-----------ADAYYLGGVPPDQLPPSL 3077
Query: 2446 RRGVTTKSFV-GCIKNLEISRSTFDLLR-NSYGVRKGCLLEPI--RSVSFLKGGYIELPP 2501
RR T V GC+K ++ DL R N+ GV GC + + R+++F G++ L
Sbjct: 3078 RRLFPTGGSVRGCVKGIKALGKYVDLKRLNTTGVSAGCTADLLVGRAMTFHGHGFLRLAL 3137
Query: 2502 KSLSPESEWLVT---FATTNSSGIILAALGGDVEKRGDREEAHVPFFSVMLIGGNIEVHV 2558
+++P + + + F + S ++ D + ++ V S+ L+ ++
Sbjct: 3138 SNVAPLTGNVYSGFGFHSAQDSALLYYRASPDGLCQVSLQQGRV---SLQLLRTEVKTQA 3194
Query: 2559 NPGDGTGLRKALLHAPTGTCSDGQAHSISLVRNRRIITVQLDENNPVEMKLGTLVESRTI 2618
DG AP A + L + ++ ++ P E+ + +
Sbjct: 3195 GFADG---------APHYVAFYSNATGVWLYVDDQLQQMKPHRGPPPEL------QPQPE 3239
Query: 2619 NVSNLYVGGIPEGEGTSLLTMRRSFHGCIKNL----------IFNLE--LLDFNSAVG-H 2665
L +GG+PE GT +F GCI N+ +F+L+ L N + G
Sbjct: 3240 GPPRLLLGGLPE-SGTIY-----NFSGCISNVFVQRLLGPQRVFDLQQNLGSVNVSTGCA 3293
Query: 2666 EQVDLDTCWLSERPKLAPDAEDSKLLPEPRAFPEQCVVDAALEYVPGAHQFGLTQNSHFI 2725
+ T L R A + S+ +P P C++ L ++QFG + +SH
Sbjct: 3294 PALQAQTPGLGPRGLQATARKASRRSRQPARHP-ACMLPPHLRTTRDSYQFGGSLSSHLE 3352
Query: 2726 LPFNQSAVRKKLSVELSIRTFASSGLIYYMAHQNQADYAVLQLHGGRLHFMFDL-GKG-R 2783
+ R S+ + + +S GL+ + A + L L HF+ + G G R
Sbjct: 3353 FVGILARHRNWPSLSMHVLPRSSRGLLLFTARLRPGSPS-LALFLSNGHFVAQMEGLGTR 3411
Query: 2784 TKVSHPALLSDGKWHTVKTDYVKRKGFITVDG-----RESPMVTVVGDGTMLDVEGLFYL 2838
+ G+WH V + K + + DG +E P G ++
Sbjct: 3412 LRAQSRQRSRPGRWHKVSVRWEKNRILLVTDGARAWSQEGPHRQ--HQGAEHPQPHTLFV 3469
Query: 2839 GGLPSQYQARKIGNITHSIPACIGDVTVNSKQLDKDSPVSAFTVNRC-YAVAQEGTYFDG 2897
GGLP+ + K+ +T C+ + ++ + L +P V C + G +F G
Sbjct: 3470 GGLPASSHSSKL-PVTVGFSGCVKRLRLHGRPL--GAPTRMAGVTPCILGPLEAGLFFPG 3526
Query: 2898 SGYAALVKEGYKVQSDVNITLEFRTSSQNGVLLGISTAKVDA-IGLELVDGKVLFHVNNG 2956
SG + DV + LE R + G++ + A+ + L++ + +VL ++G
Sbjct: 3527 SGGVITLDLPGATLPDVGLELEVRPLAVTGLIFHLGQARTPPYLQLQVTEKQVLLRADDG 3586
Query: 2957 AGRITAAYEPKTATVLCDGKWHTLQANKSKHRITLIVDGNAVGAESPHT----QSTSVDT 3012
AG + + +VLCDG+WH L KS + + L VD A+S HT + +
Sbjct: 3587 AGEFSTSV--TRPSVLCDGQWHRLAVMKSGNVLRLEVD-----AQSNHTVGPLLAAAAGA 3639
Query: 3013 NNPIYVGGYPAGVKQKCLRSQTSFRGCLRKLALIKSPQVQSFDFSRAFELHG-VFLHSCP 3071
P+Y+GG P + + ++ GC+R+LA+ +SP +R+ E+HG V CP
Sbjct: 3640 PAPLYLGGLPEPMAVQ--PWPPAYCGCMRRLAVNRSPVA----MTRSVEVHGAVGASGCP 3693
Score = 281 bits (718), Expect = 9e-75
Identities = 159/484 (32%), Positives = 214/484 (44%), Gaps = 67/484 (13%)
Query: 709 CECPQGYTGTSCESCLSGY----YRVDGILFGGICQPCECHGHAAECNVH---------- 754
C C G +C+ C G+ ++ CQ C C+GHA +C
Sbjct: 322 CTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHATDCYYDPEVDRRRASQ 381
Query: 755 ---------GVCIACAHNTTGVHCEQCLPGFYGEPSR--GTPGDCQPCACPLTIASNNFS 803
GVCI C H+TTGV+CE+CLPGFY P+ +P C+ C C S+
Sbjct: 382 SLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCE----SDFTD 437
Query: 804 PTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNPT---------------VPGESCVP 848
TC G C +C P +SG C+ CA+G+ G P+ +P V
Sbjct: 438 GTCEDLTGR---C-YCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVN 493
Query: 849 CDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCADGFYGDAVTAKNCRACECHVKG 908
CDCS A D G CL C N G HCE CA GFYG C+ C+C G
Sbjct: 494 CDCSAAGTQGNACRKDPRVGRCL-CKPNFQGTHCELCAPGFYGPG-----CQPCQCSSPG 547
Query: 909 SHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLDSGHGCRPCNCSVAGSVSDGCTDEGQ 968
C +TG C C+ G CD+C GY+ C+ C CS AG++ +GC + G+
Sbjct: 548 VADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPL---CQLCGCSPAGTLPEGCDEAGR 604
Query: 969 CHCVPGVAGKRCDRCAHGFYAYQDGSCTPCDCPHTQNTCDPETGECVCPPHTQGVKCEEC 1028
C C P AG CDRC G++ + + CD + G C C P G C+EC
Sbjct: 605 CLCQPEFAGPHCDRCRPGYHGFPNCQACTCDPRGALDQLCGAGGLCRCRPGYTGTACQEC 664
Query: 1029 EDGHWGYDAEVGCQACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGYRDFPDCV 1088
G G+ + C C+CS GS H CD +G C C+ + G CD C G +FP C
Sbjct: 665 SPGFHGFPS---CVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAYNFPYCE 721
Query: 1089 PCDCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFALRADNPLGCS 1148
C G + L + C+ C+ +V GP C+ C+ G + L NP GC+
Sbjct: 722 AGSCHPAGLAPVDPALPEAQVPCM-------CRAHVEGPSCDRCKPGFWGLSPSNPEGCT 774
Query: 1149 PCFC 1152
C C
Sbjct: 775 RCSC 778
Score = 239 bits (610), Expect = 3e-62
Identities = 152/456 (33%), Positives = 195/456 (42%), Gaps = 74/456 (16%)
Query: 709 CECPQGYTGTSCESCLSGYYRV--------------DGILFGGICQPCECHGHAAECNVH 754
C C ++G C+ C G+ + +L G C+C + N
Sbjct: 447 CYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNAC 506
Query: 755 ------GVCIACAHNTTGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHL 808
G C+ C N G HCE C PGFYG PG CQPC C +++ C
Sbjct: 507 RKDPRVGRCL-CKPNFQGTHCELCAPGFYG------PG-CQPCQCSSPGVADD---RC-- 553
Query: 809 NDGDEVVCDWCAPGYSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTG 868
D D C C G+ GA C+RCA GY+ P C C CS E CD G
Sbjct: 554 -DPDTGQCR-CRVGFEGATCDRCAPGYFHFPL-----CQLCGCSPAGTLPEG--CDEA-G 603
Query: 869 ECLKCLGNTDGAHCERCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNVT 928
CL C G HC+RC G++G NC+AC C +G+ +C GLC C+P T
Sbjct: 604 RCL-CQPEFAGPHCDRCRPGYHG----FPNCQACTCDPRGALDQLCGAG-GLCRCRPGYT 657
Query: 929 GQQCDQCLHGYYGLDSGHGCRPCNCSVAGSVSDGCTDE-GQCHCVPGVAGKRCDRCAHGF 987
G C +C G++G S C PC+CS GS+ C GQC C P V G RCD C G
Sbjct: 658 GTACQECSPGFHGFPS---CVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGA 714
Query: 988 YAY---QDGSCTPCDCPHTQNTCDPETGECVCPPHTQGVKCEECEDGHWGYDAE--VGCQ 1042
Y + + GSC P C+C H +G C+ C+ G WG GC
Sbjct: 715 YNFPYCEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSPSNPEGCT 774
Query: 1043 ACNCSLVGSTHH--RCDVVTGHCQCKSKFGGRACDQCSLGY-----RDFPDCVPCDCDLR 1095
C+C L G+ C TG C CK G+AC C G+ D+ C C CD+
Sbjct: 775 RCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGCRSCRCDIG 834
Query: 1096 GTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNE 1131
G G +C TG C C+ N GP C+E
Sbjct: 835 GALGQSCE---------PRTGVCRCRPNTQGPTCSE 861
Score = 196 bits (499), Expect = 2e-49
Identities = 127/391 (32%), Positives = 176/391 (45%), Gaps = 45/391 (11%)
Query: 819 CAPGYSGAWCERCADGYYGNPTVPG---ESCVPCDCSGNVDPSEAGHCDSVTGECLKCLG 875
C Y G C+ CA G+Y + V G CVPC C G+ D C +G C+ C
Sbjct: 1833 CPASYRGDSCQECAPGFYRD--VKGLFLGRCVPCQCHGHSD-----RCLPGSGVCVDCQH 1885
Query: 876 NTDGAHCERCADGFYGDAVT-AKNCRACECHVK---GSHSAVCHLETGL--CDCKPNVTG 929
NT+GAHCERC GF + C +C C + + + C L G C CKP G
Sbjct: 1886 NTEGAHCERCQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCLCKPGYAG 1945
Query: 930 QQCDQCLHGYYG--LDSGHGCRPCNCSVAGS----VSDGCTDEGQCH-CVPGVAGKRCDR 982
C++C G++G L G C+PC+CS G SD G C C+ G RC+
Sbjct: 1946 ASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEI 2005
Query: 983 CAHGFY--AYQDGSCTPCDC-PHTQNTCDPETGECVCPPHTQGVKCEECEDGHWGYDAEV 1039
CA GFY A G+CT CDC P CDP +G C+C G +C+ C++GH+G+D
Sbjct: 2006 CAPGFYGNALLPGNCTRCDCTPCGTEACDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGCG 2065
Query: 1040 GCQACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGYRDFPD--CVPCDCDLRGT 1097
GC+ C C + C +G C C+ G C +C+ GY P+ C C C
Sbjct: 2066 GCRPCACG-PAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLPEQGCRRCQC----- 2119
Query: 1098 SGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFALRADNPLGCSPCFCSGLSH 1157
G C+ TG C C + G +C+ C + P+G S C H
Sbjct: 2120 PGGRCD---------PHTGRCNCPPGLSGERCDTCSQQHQVPVPGGPVGHS-IHCEVCDH 2169
Query: 1158 -LCSELEDYVRTPVTLGSDQPLLRVVSQSNL 1187
+ L+D R L + LR ++ S++
Sbjct: 2170 CVVLLLDDLERAGALLPAIHEQLRGINASSM 2200
Score = 194 bits (494), Expect = 9e-49
Identities = 124/370 (33%), Positives = 160/370 (43%), Gaps = 84/370 (22%)
Query: 849 CDCSGNVDPSEAGH-CDSVTGECLKCLGNTDGAHCERCADGFY------GDAVTAKNCRA 901
C C G+ D +A D +C C NT G C+RC GF A +A C++
Sbjct: 300 CVCHGHADACDAKDPTDPFRLQCT-CQHNTCGGTCDRCCPGFNQQPWKPATANSANECQS 358
Query: 902 CECHVKGSHSAVCHLET------------------GLC-DCKPNVTGQQCDQCLHGYYG- 941
C C+ H+ C+ + G+C DC+ + TG C++CL G+Y
Sbjct: 359 CNCY---GHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRS 415
Query: 942 ----LDSGHGCRPCNCSVAGSVSDGCTDE--GQCHCVPGVAGKRCDRCAHGFYAYQDGSC 995
LDS H CR CNC +DG ++ G+C+C P +G+RCD CA GF +
Sbjct: 416 PNHPLDSPHVCRRCNCE--SDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYP 473
Query: 996 TP------------------CDCPH--TQ-NTC--DPETGECVCPPHTQGVKCEECEDGH 1032
TP CDC TQ N C DP G C+C P+ QG CE C G
Sbjct: 474 TPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGF 533
Query: 1033 WGYDAEVGCQACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGYRDFPDCVPCDC 1092
+G GCQ C CS G RCD TG C+C+ F G CD+C+ GY FP C C C
Sbjct: 534 YG----PGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPLCQLCGC 589
Query: 1093 DLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFALRADNPLGCSPCFC 1152
GT + C +E G C C+ GP C+ CR G C C C
Sbjct: 590 SPAGTLPEGC----------DEAGRCLCQPEFAGPHCDRCRPGYHGFP-----NCQACTC 634
Query: 1153 ---SGLSHLC 1159
L LC
Sbjct: 635 DPRGALDQLC 644
Score = 177 bits (450), Expect = 1e-43
Identities = 111/345 (32%), Positives = 151/345 (43%), Gaps = 49/345 (14%)
Query: 705 DVEHCECPQGYTGTSCESCLSGYYRVDGILFGGICQPCECH--GHAAE-CNVHGVCIACA 761
D C C G+ G +C+ C GY+ +CQ C C G E C+ G C+ C
Sbjct: 556 DTGQCRCRVGFEGATCDRCAPGYFHFP------LCQLCGCSPAGTLPEGCDEAGRCL-CQ 608
Query: 762 HNTTGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAP 821
G HC++C PG++G P+ CQ C C A + G +C C P
Sbjct: 609 PEFAGPHCDRCRPGYHGFPN------CQACTCDPRGALDQLC-------GAGGLCR-CRP 654
Query: 822 GYSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAH 881
GY+G C+ C+ G++G P SCVPC CS + S CD +G+C C G
Sbjct: 655 GYTGTACQECSPGFHGFP-----SCVPCHCSA--EGSLHAACDPRSGQC-SCRPRVTGLR 706
Query: 882 CERCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGL--CDCKPNVTGQQCDQCLHGY 939
C+ C G Y C A CH G L C C+ +V G CD+C G+
Sbjct: 707 CDTCVPGAYNFPY----CEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGF 762
Query: 940 YGLDSGH--GCRPCNCSVAGS---VSDGCTDEGQCHCVPGVAGKRCDRCAHGFYAYQDGS 994
+GL + GC C+C + G+ V++ GQC C P V G+ C C GF+
Sbjct: 763 WGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQAD 822
Query: 995 ---CTPCDCP---HTQNTCDPETGECVCPPHTQGVKCEECEDGHW 1033
C C C +C+P TG C C P+TQG C E H+
Sbjct: 823 YFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARDHY 867
Score = 129 bits (323), Expect = 6e-29
Identities = 69/221 (31%), Positives = 93/221 (42%), Gaps = 50/221 (22%)
Query: 289 QCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKS 348
+C C+ G C+RC PGYH P C+AC C +
Sbjct: 604 RCLCQPEFAGPHCDRCRPGYHGFP----------NCQACTCDPRG--------------- 638
Query: 349 LNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSV 408
Q G G C G C+ C G++ C PC+C GSL +
Sbjct: 639 --ALDQLCGAGGLCRCRPGYTGTACQECSPGFHG--------FPSCVPCHCSAEGSLHAA 688
Query: 409 CIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYPTCVSCGCNPVGSASDEPCT 468
C + GQC C+ TG +CD C G ++P C + C+P G A +P
Sbjct: 689 C-----------DPRSGQCSCRPRVTGLRCDTCVPGAYNFPYCEAGSCHPAGLAPVDPAL 737
Query: 469 G----PCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFC 505
PC+C+ +VEG +CDRCKPGF+ L NP GC+ C C
Sbjct: 738 PEAQVPCMCRAHVEGPSCDRCKPGFWGLSPSNPEGCTRCSC 778
Score = 128 bits (322), Expect = 8e-29
Identities = 74/245 (30%), Positives = 100/245 (40%), Gaps = 28/245 (11%)
Query: 709 CECPQGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAAECNVHGVC------IACAH 762
C C GYTGT+C+ C G++ C PC C +AE ++H C +C
Sbjct: 650 CRCRPGYTGTACQECSPGFHGFPS------CVPCHC---SAEGSLHAACDPRSGQCSCRP 700
Query: 763 NTTGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPG 822
TG+ C+ C+PG Y P G C P +P +V C C
Sbjct: 701 RVTGLRCDTCVPGAYNFPYCEA-GSCHPAG---------LAPVDPALPEAQVPC-MCRAH 749
Query: 823 YSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHC 882
G C+RC G++G E C C C C TG+C C + G C
Sbjct: 750 VEGPSCDRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCF-CKPHVCGQAC 808
Query: 883 ERCADGFYG-DAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYG 941
C DGF+G D CR+C C + G+ C TG+C C+PN G C + +Y
Sbjct: 809 ASCKDGFFGLDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARDHYL 868
Query: 942 LDSGH 946
D H
Sbjct: 869 PDLHH 873
Score = 115 bits (288), Expect = 7e-25
Identities = 72/225 (32%), Positives = 98/225 (43%), Gaps = 41/225 (18%)
Query: 287 KLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQK 346
+ QC C+ G SC RC PG+ P + G++C+ C+C D ++
Sbjct: 1934 RTQCLCKPGYAGASCERCAPGFFGNP-----LVLGSSCQPCDCSGNG-----DPNLLFSD 1983
Query: 347 KSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLS 406
T G C CL++T G CE C G+Y + + P C C+C P G +
Sbjct: 1984 CDPLT-------GACRGCLRHTTGPRCEICAPGFY-GNALLPGN---CTRCDCTPCG--T 2030
Query: 407 SVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYPTCVS---CGCNPVGSAS 463
C D HS G C CK G TG +CDRCQ G+ + C C C P S
Sbjct: 2031 EAC---DPHS--------GHCLCKAGVTGRRCDRCQEGHFGFDGCGGCRPCACGPAAEGS 2079
Query: 464 D-EPCTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFCFG 507
+ P +G C C+ G C C PG++ L E +GC C C G
Sbjct: 2080 ECHPQSGQCHCRPGTMGPQCRECAPGYWGLPE---QGCRRCQCPG 2121
Score = 113 bits (282), Expect = 3e-24
Identities = 68/198 (34%), Positives = 83/198 (41%), Gaps = 54/198 (27%)
Query: 900 RACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGL------DSGH------- 946
R C CH G+ C G C C +V G+ C +C GY+G D G
Sbjct: 1436 RPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFPNCRPCDCGARLCDELT 1495
Query: 947 ----------------------------GCRPCNCSVAG--SVSDGC--TDEGQCHCVPG 974
GC CNCS G ++D TD GQC C P
Sbjct: 1496 GQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRPN 1555
Query: 975 VAGKRCDRCAHGFYAYQDGSCTPCDCPHTQNT----CDPETGECVCPPHTQGVKCEECED 1030
V G+RCD C+ GF+ Y C PCDC H T CDP TG+C C + QG KC++C
Sbjct: 1556 VTGRRCDTCSPGFHGYP--RCRPCDC-HEAGTAPGVCDPLTGQCYCKENVQGPKCDQCSL 1612
Query: 1031 GHWGYDA--EVGCQACNC 1046
G + DA GC C C
Sbjct: 1613 GTFSLDAANPKGCTRCFC 1630
Score = 112 bits (280), Expect = 6e-24
Identities = 71/219 (32%), Positives = 89/219 (40%), Gaps = 57/219 (26%)
Query: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNN---HSDTCDPNTGK 1418
C+C P G C+ CAPG++ GP C PC C++ D CDP+TG+
Sbjct: 515 CLCKPNFQGTHCELCAPGFY----------GP-----GCQPCQCSSPGVADDRCDPDTGQ 559
Query: 1419 CLNCGDNTAGDHCDVCTSGYY-------------GKVTGSASDCALCACP---------- 1455
C C G CD C GY+ G + + C C
Sbjct: 560 C-RCRVGFEGATCDRCAPGYFHFPLCQLCGCSPAGTLPEGCDEAGRCLCQPEFAGPHCDR 618
Query: 1456 -----HSPPASFSPTCVLEGDHDFRCDA-----CLLGYEGKHCERCSSSYYGNPQTPGGS 1505
H P + TC G D C A C GY G C+ CS ++G P S
Sbjct: 619 CRPGYHGFPNCQACTCDPRGALDQLCGAGGLCRCRPGYTGTACQECSPGFHGFP-----S 673
Query: 1506 CQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDECEP 1544
C C C+ GS+H CD SGQC CR +GLRCD C P
Sbjct: 674 CVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVP 712
Score = 106 bits (264), Expect = 4e-22
Identities = 74/238 (31%), Positives = 97/238 (40%), Gaps = 39/238 (16%)
Query: 1364 CPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSD----TCDPNTGKC 1419
C T G +C+ C PG++R PL +P V CN SD TC+ TG+C
Sbjct: 396 CQHHTTGVNCERCLPGFYRSP--------NHPLDSPHVCRRCNCESDFTDGTCEDLTGRC 447
Query: 1420 LNCGDNTAGDHCDVCTSGYYG-----KVTGSASDCA--------LCACPHSPPASFSPTC 1466
C N +G+ CDVC G+ G S++D + C S + C
Sbjct: 448 Y-CRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNAC 506
Query: 1467 VLEGDHDFRCDACLL--GYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRT 1524
D R CL ++G HCE C+ +YG PG CQ C C+ G CD
Sbjct: 507 ----RKDPRVGRCLCKPNFQGTHCELCAPGFYG----PG--CQPCQCSSPGVADDRCDPD 556
Query: 1525 SGQCVCRLGASGLRCDECEPRHILMETDCVSCDDECVGVLLNDLDEIGDAVLSLNLTG 1582
+GQC CR+G G CD C P + C C G L DE G + G
Sbjct: 557 TGQCRCRVGFEGATCDRCAPGYFHFPL-CQLCGCSPAGTLPEGCDEAGRCLCQPEFAG 613
Score = 98.2 bits (243), Expect = 1e-19
Identities = 68/214 (31%), Positives = 90/214 (42%), Gaps = 35/214 (16%)
Query: 1358 LLENCVCPPGTVGFSCQDCAPGYHRGKLPA-----GSDRGPRPLVAPC---VPCSCN--- 1406
L C C P G C CA G+ P+ S R V P V C C+
Sbjct: 443 LTGRCYCRPNFSGERCDVCAEGF--TGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAG 500
Query: 1407 NHSDTC--DPNTGKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSP 1464
+ C DP G+CL C N G HC++C G+YG C C C S P
Sbjct: 501 TQGNACRKDPRVGRCL-CKPNFQGTHCELCAPGFYG------PGCQPCQC--SSPGVADD 551
Query: 1465 TCVLEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRT 1524
C D D C +G+EG C+RC+ Y+ P CQ C C+P G++ CD
Sbjct: 552 RC----DPDTGQCRCRVGFEGATCDRCAPGYFHFP-----LCQLCGCSPAGTLPEGCDE- 601
Query: 1525 SGQCVCRLGASGLRCDECEP-RHILMETDCVSCD 1557
+G+C+C+ +G CD C P H +CD
Sbjct: 602 AGRCLCQPEFAGPHCDRCRPGYHGFPNCQACTCD 635
Score = 93.6 bits (231), Expect = 3e-18
Identities = 64/225 (28%), Positives = 90/225 (40%), Gaps = 52/225 (23%)
Query: 290 CQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKSL 349
C+C G +C C PG+H P +C C+C + SL
Sbjct: 650 CRCRPGYTGTACQECSPGFHGFP----------SCVPCHCSAEG--------------SL 685
Query: 350 NTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSVC 409
+ A R G +C G+ C+TC+ G Y PY C +C P G
Sbjct: 686 HAACDPRSGQC--SCRPRVTGLRCDTCVPGAYN----FPY----CEAGSCHPAGLAP--- 732
Query: 410 IKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGY-----KDYPTCVSCGCNPVGS--- 461
+ L + P C C+ G CDRC+ G+ + C C C+ G+
Sbjct: 733 ----VDPALPEAQVP--CMCRAHVEGPSCDRCKPGFWGLSPSNPEGCTRCSCDLRGTLGG 786
Query: 462 -ASDEPCTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFC 505
A +P TG C CK +V G+AC CK GF+ L + + GC C C
Sbjct: 787 VAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGCRSCRC 831
Score = 79.3 bits (194), Expect = 5e-14
Identities = 57/234 (24%), Positives = 77/234 (32%), Gaps = 62/234 (26%)
Query: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSD---TCDPNTGK 1418
C C PG G +CQ+C+PG+H CVPC C+ CDP +G+
Sbjct: 650 CRCRPGYTGTACQECSPGFHG--------------FPSCVPCHCSAEGSLHAACDPRSGQ 695
Query: 1419 CLNCGDNTAGDHCDVCTSGYYGKVTGSASDC----------------ALCAC-------- 1454
C +C G CD C G Y A C C C
Sbjct: 696 C-SCRPRVTGLRCDTCVPGAYNFPYCEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPS 754
Query: 1455 ------------PHSPPASFSPTCVLEGDHDFRCDA--------CLLGYEGKHCERCSSS 1494
P +P +C L G + C G+ C C
Sbjct: 755 CDRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDG 814
Query: 1495 YYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDECEPRHIL 1548
++G Q C+ C C+ G++ C+ +G C CR G C E H L
Sbjct: 815 FFGLDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARDHYL 868
Score = 77.0 bits (188), Expect = 3e-13
Identities = 51/164 (31%), Positives = 72/164 (43%), Gaps = 26/164 (15%)
Query: 1403 CSCNNHSDTC------DPNTGKCLNCGDNTAGDHCDVCTSGYYGK-----VTGSASDCAL 1451
C C+ H+D C DP +C C NT G CD C G+ + SA++C
Sbjct: 300 CVCHGHADACDAKDPTDPFRLQC-TCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQS 358
Query: 1452 CAC-PHSPPASFSP-------TCVLEGDHDFR--CDACLLGYEGKHCERCSSSYYGNPQT 1501
C C H+ + P + L+G + C C G +CERC +Y +P
Sbjct: 359 CNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNH 418
Query: 1502 PGGS---CQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDEC 1542
P S C++C+C G C+ +G+C CR SG RCD C
Sbjct: 419 PLDSPHVCRRCNCE-SDFTDGTCEDLTGRCYCRPNFSGERCDVC 461
Score = 47.4 bits (111), Expect = 2e-04
Identities = 44/175 (25%), Positives = 64/175 (36%), Gaps = 43/175 (24%)
Query: 273 YGHASSC------PWDETTKKLQ--CQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTC 324
Y A SC P D + Q C C + G SC+RC PG+ W + S+ C
Sbjct: 719 YCEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGF----WGL-SPSNPEGC 773
Query: 325 EACNCHNKAKDCYYDESVAKQKKSLNTAGQFR-GGGVCINCLQNTMGINCETCIDGYYRP 383
C+C + +L + + G G C C + G C +C DG++
Sbjct: 774 TRCSCDLRG--------------TLGGVAECQPGTGQCF-CKPHVCGQACASCKDGFFGL 818
Query: 384 HKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKC 438
+ + CR C CD G+L C + G C C+ G C
Sbjct: 819 DQADYF---GCRSCRCDIGGALGQSC-----------EPRTGVCRCRPNTQGPTC 859
Score = 44.7 bits (104), Expect = 0.001
Identities = 20/61 (32%), Positives = 28/61 (45%), Gaps = 2/61 (3%)
Query: 454 CGCNPVGSASD--EPCTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFCFGVSDV 511
CGC+ VG+ EP G C C +V G+ C RC G++ P C C ++
Sbjct: 1438 CGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFPNCRPCDCGARLCDELTGQ 1497
Query: 512 C 512
C
Sbjct: 1498 C 1498
>gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens]
Length = 1724
Score = 405 bits (1040), Expect = e-112
Identities = 445/1787 (24%), Positives = 753/1787 (42%), Gaps = 210/1787 (11%)
Query: 1374 QDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKCLNCGDNTAGDHCDV 1433
Q C+PGY+R + R CVPC+CN HS+ C +G C+NC NTAG+HC+
Sbjct: 57 QGCSPGYYRDHKGLYTGR--------CVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCER 108
Query: 1434 CTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGDHDFRCDACLLGYEGKHCERCSS 1493
C GYYG + C C CPH+ SF+ CV+ G D RC +C GY G CERC+
Sbjct: 109 CQEGYYGNAVHGS--CRACPCPHTN--SFATGCVVNGG-DVRC-SCKAGYTGTQCERCAP 162
Query: 1494 SYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDECEPRHILMETDC 1553
Y+GNPQ GGSCQ C CN +G + G C +G C+ + +EC+ DC
Sbjct: 163 GYFGNPQKFGGSCQPCSCNSNGQL-GSCHPLTGDCINQEPKDSSPAEECD--------DC 213
Query: 1554 VSCDDECVGVLLNDLDEIGDAV--LSLNLTGIIPVPYGILS---NLENTTKYLQESLLKE 1608
D CV LLNDL +G+ + + L G+ G+L ++E K L+ LL
Sbjct: 214 ----DSCVMTLLNDLATMGEQLRLVKSQLQGL-SASAGLLEQMRHMETQAKDLRNQLLNY 268
Query: 1609 NMQKDLGKIKLEGVA-------EETDNLQKKLTRMLASTQKVNRATERIFKESQDLAIAI 1661
K+EG+ +E + LQ+K Q +N R + +++L + I
Sbjct: 269 RSAISNHGSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLNNNVNRATQSAKELDVKI 328
Query: 1662 ERLQMSITEIMEKTTLNQTLDEDFLLPNSTLQNMQQNGTSLLEIMQIRDFTQLHQNATLE 1721
+ + ++ ++++ ++ T E +P+ ++ ++ R+F + + A +
Sbjct: 329 KNVIRNVHILLKQ--ISGTDGEGNNVPSGDFSREWAEAQRMMRELRNRNFGKHLREAEAD 386
Query: 1722 LKAAEDLLSQIQENYQKPLEELEVLKEAASHVLSKHNNELKAAEALVREAEAKMQESNHL 1781
+ ++ LL++I+ + E L + L+++ +L A ++EA A+ +++N L
Sbjct: 387 KRESQLLLNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQANGL 446
Query: 1782 LLMVNANLREFSDKKLHVQEEQNLTSELIVQGRGLIDAAAAQTDAVQDALEHLEDHQDKL 1841
N R + V+E +L S+ + D++ QT+ +E + +KL
Sbjct: 447 N---QENERALGAIQRQVKEINSLQSDF-TKYLTTADSSLLQTNIALQLMEKSQKEYEKL 502
Query: 1842 LLWSAKIRHHIDDLVMHMSQR-NAVDLVYRAEDHAAEFQRLADVLYSGLENIRNVSLN-- 1898
+ R + D V +S+ LV AE HA Q LA L N L
Sbjct: 503 AASLNEARQELSDKVRELSRSAGKTSLVEEAEKHARSLQELAKQLEEIKRNASGDELVRC 562
Query: 1899 ATSAAYVHYNIQSLIEESEELARDAHRTVTETSL---LSESLVSNGKAAVQRSSRFLKEG 1955
A AA + NI + I+ +E+ A A + +E++L + E L K S + L E
Sbjct: 563 AVDAATAYENILNAIKAAEDAANRA-ASASESALQTVIKEDLPRKAKTLSSNSDKLLNEA 621
Query: 1956 NNLSRKLPGIALELSELRNKTNRFQENAVEITRQTNESLLILRAIPKGIRDKGAKTKELA 2015
+KL E+ N Q+ +T Q L + G+ +
Sbjct: 622 KMTQKKLK------QEVSPALNNLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGDIDAM 675
Query: 2016 TSASQSAVSTLRDVAGLSQELLNT-SASLSRVNTTLRETH-----QLLQDSTMATLLAGR 2069
S+++S V D+ + LN + R+ T T + L D+ +
Sbjct: 676 ISSAKSMVRKANDITDEVLDGLNPIQTDVERIKDTYGRTQNEDFKKALTDADNSVNKLTN 735
Query: 2070 KVKDVEIQANLLFDRLKPLKMLEENLSRNLSEIKLLISQARKQAASIKVAVSAD-RDCIR 2128
K+ D+ + + +L PL N+S N+ I+ LI QAR A+ + V + + + +
Sbjct: 736 KLPDLWRKIESINQQLLPLG----NISDNMDRIRELIQQARDAASKVAVPMRFNGKSGVE 791
Query: 2129 AYQPQISSTNYNTLTLNVKTQEPDN---------LLFYLGSSTAS-DFLAVEMRRGRVAF 2178
P +L++ Q P++ + YLG+ AS D++ + + G++
Sbjct: 792 VRLPNDLEDLKGYTSLSLFLQRPNSRENGGTENMFVMYLGNKDASRDYIGMAVVDGQLTC 851
Query: 2179 LWDLGSGSTRLEFPDFPIDDNRWHSIHVARFGNIGSLSVKEMSSNQKSPTKTSKSPGTAN 2238
+++LG L+ ++ + + + + + TS P T
Sbjct: 852 VYNLGDREAELQVDQILTKSETKEAV----MDRVKFQRIYQFARLNYTKGATSSKPETPG 907
Query: 2239 VLDV---NNSTLM---------FVGGLGGQIKKSPAVKVTHFKGCLGEAFLNGKSIGLWN 2286
V D+ N++TL+ +VGG K + +KGC+ LN + L+N
Sbjct: 908 VYDMDGRNSNTLLNLDPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELDDLNENVLSLYN 967
Query: 2287 YIE----REGKCRGCFGSSQNEDPSFHFDGSGYSVVEKSLPATVTQIIMLFNTFSPNGLL 2342
+ + + C + D ++ F+G+GY+ V A + T GLL
Sbjct: 968 FKKTFNLNTTEVEPCRRRKEESDKNY-FEGTGYARVPTQPHAPIPTFGQTIQTTVDRGLL 1026
Query: 2343 LYLGSYGTKDFLSIELFRGRVKVMTDLGSG-PITLLTDRRYNNGTWYKIAFQRNRKQGVL 2401
+ + G + F+S+ + G++ V L S P NNG + I + + Q +
Sbjct: 1027 FFAEN-GDR-FISLNIEDGKLMVRYKLNSELPKERGVGDAINNGRDHSIQIKIGKLQKRM 1084
Query: 2402 AV-IDAYNTSNKETKQGETPGASSDLNRLDKDPIYVGGLPRSRVVRRGVTTKSFVGCIKN 2460
+ +D NT GE D Y+GG+P + R ++T +F GC+KN
Sbjct: 1085 WINVDVQNT----IIDGEV---------FDFSTYYLGGIPIAIRERFNISTPAFRGCMKN 1131
Query: 2461 LEISRSTFDLLRNSYGVRKGCLLE--PIRSVSFLKGGYIELPPKSLSPESEWLVTFA--T 2516
L+ S L ++ GV K C + +RS SF +GG + L P +F T
Sbjct: 1132 LK-KTSGVVRLNDTVGVTKKCSEDWKLVRSASFSRGGQLSFTDLGLPPTDHLQASFGFQT 1190
Query: 2517 TNSSGIILAALGGDVEKRGDREEAHVPFFSVMLIGGNIEVHVNPGDGTGLRKALLHAPTG 2576
SGI+L + V L G IE+ + G+ + K+
Sbjct: 1191 FQPSGILLD------------HQTWTRNLQVTLEDGYIELSTSDS-GSPIFKS-----PQ 1232
Query: 2577 TCSDGQAHSISLVRN----RRIITVQLDENNPVEMKLGTLVESRTINVSNLYVGGIPEGE 2632
T DG H +S++ + R +I QL N+ +L + SR +L +GG
Sbjct: 1233 TYMDGLLHYVSVISDNSGLRLLIDDQLLRNSK---RLKHISSSR----QSLRLGG----- 1280
Query: 2633 GTSLLTMRRSFHGCIKN-----LIFNLELLDFNSAVGHEQVDLDTCWLSERPKL------ 2681
+F GCI N L + E+LD S V L C L++ P L
Sbjct: 1281 --------SNFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLGGCSLNKPPFLMLLKGS 1332
Query: 2682 -----APDAEDSKLLPE-PRAFPEQCVV-DAALEYVP------GAHQFGLTQNSHFILPF 2728
++LL + P A P V A +P GA QFG SH +
Sbjct: 1333 TRFNKTKTFRINQLLQDTPVASPRSVKVWQDACSPLPKTQANHGALQFGDIPTSHLLFKL 1392
Query: 2729 NQSAVRKKLSVELSIRTFASSGLIYYMAHQNQADYAVLQLHGGRLHFMFDLGKGRTKVSH 2788
Q ++ + + ++T +S GL+++ +N + L L GRL F + ++
Sbjct: 1393 PQELLKPRSQFAVDMQTTSSRGLVFHTGTKNS--FMALYLSKGRLVFALGTDGKKLRIKS 1450
Query: 2789 PALLSDGKWHTVKTDYVKRKGFITVDGRESPMVTVVGDGTMLDVEGLFYLGGLPSQYQAR 2848
+DGKWHTV + KG + VDG + ++ G+ T + + YLG PS +
Sbjct: 1451 KEKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNST-ISIRAPVYLGSPPS---GK 1506
Query: 2849 KIGNITHSIPACIGDVTVNSKQLDKDSPVSAFTVNRCY-AVAQEGTYFDGSGYAALVKEG 2907
T+S C+ + ++SK L +P S+F V+ C ++G YF G ++
Sbjct: 1507 PKSLPTNSFVGCLKNFQLDSKPL--YTPSSSFGVSSCLGGPLEKGIYFSEEGGHVVLAHS 1564
Query: 2908 YKVQSDVNITLEFRTSSQNGVLLGISTAKVDAIGLELVDGKVLFHVNNGAGRITAAYEPK 2967
+ + + R S G+L+ I + + + L GKV +++GAG + + PK
Sbjct: 1565 VLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYLEAGKVTASMDSGAGGTSTSVTPK 1624
Query: 2968 TATVLCDGKWHTLQANKSKH--RITLIVDGNAVGAESPHTQSTSVDTNNPIYVGGYPAGV 3025
+ LCDG+WH++ +H + L D + + P ++ T P+++GG PA +
Sbjct: 1625 QS--LCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFPPAS---TQEPLHLGGAPANL 1679
Query: 3026 KQKCLRSQTSFRGCLRKLALIKSPQVQSFDFSRAFELHG-VFLHSCP 3071
+ SF GCLR + + P + A E+ G V L+ CP
Sbjct: 1680 TTLRIPVWKSFFGCLRNIHVNHIP----VPVTEALEVQGPVSLNGCP 1722
Score = 145 bits (365), Expect = 8e-34
Identities = 72/168 (42%), Positives = 95/168 (56%), Gaps = 13/168 (7%)
Query: 721 ESCLSGYYRVDGILFGGICQPCECHGHAAEC-NVHGVCIACAHNTTGVHCEQCLPGFYGE 779
+ C GYYR L+ G C PC C+GH+ +C + G+C+ C HNT G HCE+C G+YG
Sbjct: 57 QGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGN 116
Query: 780 PSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNP 839
G+ C+ C CP T N+F+ C +N GD V C C GY+G CERCA GY+GNP
Sbjct: 117 AVHGS---CRACPCPHT---NSFATGCVVNGGD-VRCS-CKAGYTGTQCERCAPGYFGNP 168
Query: 840 TVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCAD 887
G SC PC C+ N + G C +TG+C+ D + E C D
Sbjct: 169 QKFGGSCQPCSCNSN---GQLGSCHPLTGDCIN-QEPKDSSPAEECDD 212
Score = 108 bits (270), Expect = 8e-23
Identities = 56/149 (37%), Positives = 79/149 (53%), Gaps = 18/149 (12%)
Query: 831 CADGYY-GNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCADGF 889
C+ GYY + + CVPC+C+G+ + C +G C+ C NT G HCERC +G+
Sbjct: 59 CSPGYYRDHKGLYTGRCVPCNCNGH-----SNQCQDGSGICVNCQHNTAGEHCERCQEGY 113
Query: 890 YGDAVTAKNCRACECHVKGSHSAVCHLETG--LCDCKPNVTGQQCDQCLHGYYGLDS--G 945
YG+AV +CRAC C S + C + G C CK TG QC++C GY+G G
Sbjct: 114 YGNAVHG-SCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFG 172
Query: 946 HGCRPCNCSVAGSVSDGCTDEGQCHCVPG 974
C+PC+C+ G + G CH + G
Sbjct: 173 GSCQPCSCNSNGQL-------GSCHPLTG 194
Score = 103 bits (256), Expect = 3e-21
Identities = 53/155 (34%), Positives = 73/155 (47%), Gaps = 10/155 (6%)
Query: 885 CADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLC-DCKPNVTGQQCDQCLHGYYGLD 943
C+ G+Y D R C+ G HS C +G+C +C+ N G+ C++C GYYG
Sbjct: 59 CSPGYYRDHKGLYTGRCVPCNCNG-HSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNA 117
Query: 944 SGHGCRPCNCSVAGSVSDGCTDEG---QCHCVPGVAGKRCDRCAHGFYAYQD---GSCTP 997
CR C C S + GC G +C C G G +C+RCA G++ GSC P
Sbjct: 118 VHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQP 177
Query: 998 CDCPHT--QNTCDPETGECVCPPHTQGVKCEECED 1030
C C +C P TG+C+ EEC+D
Sbjct: 178 CSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDD 212
Score = 92.0 bits (227), Expect = 8e-18
Identities = 57/188 (30%), Positives = 77/188 (40%), Gaps = 42/188 (22%)
Query: 304 CCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCIN 363
C PGY++ G + C CNC+ + C G G+C+N
Sbjct: 59 CSPGYYRD--HKGLYTG--RCVPCNCNGHSNQCQ------------------DGSGICVN 96
Query: 364 CLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQ 423
C NT G +CE C +GYY CR C C S ++ C+ NG
Sbjct: 97 CQHNTAGEHCERCQEGYY-----GNAVHGSCRACPCPHTNSFATGCVV--------NGGD 143
Query: 424 PGQCPCKEGYTGEKCDRCQLGYKDYP-----TCVSCGCNPVGS-ASDEPCTGPCVCKENV 477
+C CK GYTG +C+RC GY P +C C CN G S P TG C+ +E
Sbjct: 144 V-RCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPK 202
Query: 478 EGKACDRC 485
+ + C
Sbjct: 203 DSSPAEEC 210
Score = 90.5 bits (223), Expect = 2e-17
Identities = 54/172 (31%), Positives = 76/172 (44%), Gaps = 19/172 (11%)
Query: 983 CAHGFY----AYQDGSCTPCDCPHTQNTCDPETGECV-CPPHTQGVKCEECEDGHWGYDA 1037
C+ G+Y G C PC+C N C +G CV C +T G CE C++G++G
Sbjct: 59 CSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAV 118
Query: 1038 EVGCQACNCSLVGSTHHRCDVVTG--HCQCKSKFGGRACDQCSLGYRDFP-----DCVPC 1090
C+AC C S C V G C CK+ + G C++C+ GY P C PC
Sbjct: 119 HGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPC 178
Query: 1091 DCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFALRAD 1142
C+ G G +C+ G C E + P +E C++C L D
Sbjct: 179 SCNSNGQLG-SCHPLTGDCINQEPKDSSPAEE------CDDCDSCVMTLLND 223
Score = 70.9 bits (172), Expect = 2e-11
Identities = 55/188 (29%), Positives = 71/188 (37%), Gaps = 37/188 (19%)
Query: 257 YYYSIKDISVGGM--CICYGHASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWR 314
YY K + G C C GH++ C + + C+HNT GE C RC GY+
Sbjct: 63 YYRDHKGLYTGRCVPCNCNGHSNQC---QDGSGICVNCQHNTAGEHCERCQEGYY----- 114
Query: 315 PGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCE 374
G G +C AC C S T GG V +C G CE
Sbjct: 115 -GNAVHG-SCRACPC--------------PHTNSFATGCVVNGGDVRCSCKAGYTGTQCE 158
Query: 375 TCIDGYY-RPHKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGY 433
C GY+ P K C+PC+C+ G L S L D N + P +E
Sbjct: 159 RCAPGYFGNPQKFG----GSCQPCSCNSNGQLGSC---HPLTGDCINQEPKDSSPAEE-- 209
Query: 434 TGEKCDRC 441
+ CD C
Sbjct: 210 -CDDCDSC 216
Score = 69.7 bits (169), Expect = 4e-11
Identities = 40/107 (37%), Positives = 50/107 (46%), Gaps = 13/107 (12%)
Query: 711 CPQGYTGTSCESCLSGYYRVDGILFGGICQPCEC---HGHAAECNVHG--VCIACAHNTT 765
C G CE C GYY G G C+ C C + A C V+G V +C T
Sbjct: 97 CQHNTAGEHCERCQEGYY---GNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYT 153
Query: 766 GVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGD 812
G CE+C PG++G P + G CQPC+C SN +CH GD
Sbjct: 154 GTQCERCAPGYFGNPQK-FGGSCQPCSC----NSNGQLGSCHPLTGD 195
Score = 63.9 bits (154), Expect = 2e-09
Identities = 41/141 (29%), Positives = 55/141 (39%), Gaps = 30/141 (21%)
Query: 376 CIDGYYRPHKVSPYEDEPCRPCNCDPVGSL----SSVCIKDDLHSDLHNGKQPGQCPCKE 431
C GYYR HK Y C PCNC+ + S +C+ C+
Sbjct: 59 CSPGYYRDHK-GLYTGR-CVPCNCNGHSNQCQDGSGICVN-----------------CQH 99
Query: 432 GYTGEKCDRCQLGYKD---YPTCVSCGCNPVGSASDEPCTGP----CVCKENVEGKACDR 484
GE C+RCQ GY + +C +C C S + C CK G C+R
Sbjct: 100 NTAGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCER 159
Query: 485 CKPGFYNLKEKNPRGCSECFC 505
C PG++ +K C C C
Sbjct: 160 CAPGYFGNPQKFGGSCQPCSC 180
Score = 54.7 bits (130), Expect = 1e-06
Identities = 38/109 (34%), Positives = 50/109 (45%), Gaps = 18/109 (16%)
Query: 694 SSNAIDLVVAADVEHCECPQGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAAECNV 753
+S A VV C C GYTGT CE C GY+ + FGG CQPC CN
Sbjct: 131 NSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFG-NPQKFGGSCQPC-------SCNS 182
Query: 754 HGVCIACAHNTTGVHCEQCLPGFYGEPSRGTPG-DCQPC-ACPLTIASN 800
+G +C H TG Q EP +P +C C +C +T+ ++
Sbjct: 183 NGQLGSC-HPLTGDCINQ-------EPKDSSPAEECDDCDSCVMTLLND 223
Score = 54.7 bits (130), Expect = 1e-06
Identities = 28/79 (35%), Positives = 37/79 (46%), Gaps = 13/79 (16%)
Query: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSD--TCDPNTGKC 1419
C C G G C+ CAPGY P+ C PCSCN++ +C P TG C
Sbjct: 146 CSCKAGYTGTQCERCAPGYFGN---------PQKFGGSCQPCSCNSNGQLGSCHPLTGDC 196
Query: 1420 LN--CGDNTAGDHCDVCTS 1436
+N D++ + CD C S
Sbjct: 197 INQEPKDSSPAEECDDCDS 215
Score = 36.2 bits (82), Expect = 0.51
Identities = 26/86 (30%), Positives = 33/86 (38%), Gaps = 19/86 (22%)
Query: 1072 RACDQCSLGY-RDFPD-----CVPCDCDLRGTSGDACNLEQGLCGCVEETGACP-CKENV 1124
R CS GY RD CVPC+C+ G S C + +G C C+ N
Sbjct: 54 RPSQGCSPGYYRDHKGLYTGRCVPCNCN--GHSNQ----------CQDGSGICVNCQHNT 101
Query: 1125 FGPQCNECREGTFALRADNPLGCSPC 1150
G C C+EG + PC
Sbjct: 102 AGEHCERCQEGYYGNAVHGSCRACPC 127
>gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
Length = 1816
Score = 394 bits (1011), Expect = e-108
Identities = 426/1830 (23%), Positives = 765/1830 (41%), Gaps = 214/1830 (11%)
Query: 1383 GKLPAGSDRGP----RPLVAPCVPCSCNNHSDTCDPNTGKCLNCGDNTAGDHCDVCTSGY 1438
G+LP +++ L CVPC CN +S+ C +G C++C NT G+HC+ C GY
Sbjct: 58 GRLPPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGY 117
Query: 1439 YG-KVTGSASDCALCACPHSPPASFSPTCVLEGDHDFRCDACLLGYEGKHCERCSSSYYG 1497
G + G+ C C CP A+F+ +C + + RC C Y G +CERC+ YYG
Sbjct: 118 IGDSIRGAPQFCQPCPCPLPHLANFAESCYRK-NGAVRC-ICNENYAGPNCERCAPGYYG 175
Query: 1498 NPQTPGGSCQKCDCNPHGS---VHGDCDRTSGQC-VCRLGASGLRCDECEPRH---ILME 1550
NP G +C+KCDC+ + + DCD +GQC C +G +C+ C P + +
Sbjct: 176 NPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIA 235
Query: 1551 TDCVSCD------DECVGVLLND---------------LDEIGDAVLSL--NLTGIIPVP 1587
+C C+ D G L + D + A LS+ +G++ V
Sbjct: 236 KNCAVCNCGGGPCDSVTGECLEEGFEPPTGCDKCVWDLTDALRLAALSIEEGKSGVLSVS 295
Query: 1588 YGILS----NLENTTKYLQESLLKE-NMQKDLGKIKLEGVAEETDNLQKKLTRMLASTQK 1642
G + N N T YL ++ L E Q L KI++ +L + ++ +
Sbjct: 296 SGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKENQ 355
Query: 1643 VNRATERIFKESQDLAIAIERLQMSITEIMEK-TTLNQTL----DEDFLLPNSTLQNMQQ 1697
+R + + KES D +L ++ +K +N + +E L P + +
Sbjct: 356 ASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVL 415
Query: 1698 NGTSLLEIMQIRDFTQLHQNATLELKAAEDLLSQIQENYQKPLEELEVLKEAASHVLSKH 1757
L EI + F + E A +LLSQ E++Q+ E L L +
Sbjct: 416 AQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQ-AESWQRLHNETRTLFPVVLEQLDDY 474
Query: 1758 NNELKAAEALVREAEAKMQESNHLLLMVNANLREFSDKKLHVQEEQNLTSELIVQGRGLI 1817
N +L + EA Q N++ + N + ++ H ++++ + ++ V L
Sbjct: 475 NAKLSDLQ------EALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLS 528
Query: 1818 DAAAAQTDAVQDALEHLEDHQDKLLLWSAKIRHHIDDLVMHMSQRNAV--DLVYRAEDHA 1875
+A + T + L L+D A+I +L + +S + + DLV A DHA
Sbjct: 529 TSADSLT-TPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHA 587
Query: 1876 AEFQRLADVLYSGL--ENIRNVSLNATSAAYVHYNIQSLIEESEELARDAHRTVTETSLL 1933
+ Q+ A+ L L ++ + A A+ V+ NI + + E+ E A A T
Sbjct: 588 QDLQQEANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDA 647
Query: 1934 SESLVSNGKAAVQRSSRFLKEGNNLSRKLPGIALE-LSELRNKTNRFQENAVEITRQTNE 1992
+ + S L + L K + E +++ + + + ++
Sbjct: 648 VSGIDTQIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSD 707
Query: 1993 SLLILRAIPKG-IRDKGAKTKELATSASQSAVSTLRDVAGLSQELLNTSASLSRVNTTLR 2051
++ L+A +G + + +++ + A+++ + + A ++ L N S +L +++
Sbjct: 708 AVKQLQAAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAY 767
Query: 2052 ETHQLLQDSTMATLLAGRKVKDVEIQANLLFDRLKPL--KMLEENLSRNLSEIKLLISQA 2109
T A A V+++ L D+L+ + K N+S ++ I+ LI+Q
Sbjct: 768 NT---------AVNSARDAVRNLTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQT 818
Query: 2110 RKQAASIKVAVSADRDCIRAYQPQISSTN---YNTLTLNVK--------TQEPDNLLFYL 2158
R A+ I+V++ D + S + + +L+L +K T+ D + YL
Sbjct: 819 RSVASKIQVSMMFDGQSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYL 878
Query: 2159 GSSTA-SDFLAVEMRRGRVAFLWDLGSGSTRLEFPDFPIDDNRWHS----IHVARFGNIG 2213
GS A +++ + ++ + ++++LG+ + P+ + W + + + R G G
Sbjct: 879 GSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPV--SSWPAYFSIVKIERVGKHG 936
Query: 2214 S--LSVKEMSSN-QKSPTKTSKSPGTANVLDVN-NSTLMFVGGLGGQIKKSPAVKVTHFK 2269
L+V +SS ++ K + G ++LD++ T+ +VGG+ K ++ + F
Sbjct: 937 KVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFV 996
Query: 2270 GCLGEAFLNGKSIGLWNYIEREGK--------CRGCFGSSQNEDPSFHFDGSGYSVV--- 2318
GCL A LN I L+N+ R +Q+ S+ FDGSGY+VV
Sbjct: 997 GCLELATLNNDVISLYNFKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDI 1056
Query: 2319 -EKSLPATVTQIIMLFNTFSPNGLLLYLGSYGTKDFLSIELFRGRVKVMTDLG--SGPIT 2375
+ VT+ + T + NGL+L + F +E+ G + V D G GP+
Sbjct: 1057 TRRGKFGQVTRFDIEVRTPADNGLILLM--VNGSMFFRLEMRNGYLHVFYDFGFSGGPVH 1114
Query: 2376 L---LTDRRYNNGTWYKIAFQRNRKQGVLAVIDAYNTSNKETKQGETPGASSDLNRLDKD 2432
L L + N+ +++I+ + + ++ V+D + + + ++ + P
Sbjct: 1115 LEDTLKKAQINDAKYHEISIIYHNDKKMILVVDRRHVKSMDNEKMKIPFTD--------- 1165
Query: 2433 PIYVGGLP----RSRVVRRGVTTK-SFVGCIKNLEISRSTFDLLR--NSYGVRKGCLLEP 2485
IY+GG P +SR +R + +F GC+K + + F+LL + GV GC +
Sbjct: 1166 -IYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQKKDFNLLEQTETLGVGYGCPEDS 1224
Query: 2486 I--RSVSFLKGGYIELPPK-SLSPESEWLVTFATTNSSGIIL-AALGGDVEKRGDREEAH 2541
+ R F +I K S E F T +G++ A G DV
Sbjct: 1225 LISRRAYFNGQSFIASIQKISFFDGFEGGFNFRTLQPNGLLFYYASGSDV---------- 1274
Query: 2542 VPFFSVMLIGGNIEVHVNPGDGTGLRKALLHAPTGTCSDGQAH----SISLVRNRRII-T 2596
FS+ L G + + V G++ + + +DG +H S+S R I+
Sbjct: 1275 ---FSISLDNGTVIMDVK-----GIK---VQSVDKQYNDGLSHFVISSVSPTRYELIVDK 1323
Query: 2597 VQLDENNPVEMKLGTLVESRTINVSNLYVGGIPEGEGTSLLTMRRSFHGCIKNLIF---- 2652
++ NP + K +E + Y GG P + +F GCI N F
Sbjct: 1324 SRVGSKNPTKGK----IEQTQASEKKFYFGGSP------ISAQYANFTGCISNAYFTRVD 1373
Query: 2653 -NLELLDFNSAVGHEQVDLDTCWLS--------------ERPKLAPDAEDSKLLPEPRAF 2697
++E+ DF L C + +PK + + + K P
Sbjct: 1374 RDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWD 1433
Query: 2698 P-------------EQCVVDAALEYVPGAHQFGLTQNSHFILPFNQSAVRKKLSVELSIR 2744
P C + + + A+Q+G T NS + K + +R
Sbjct: 1434 PVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLR 1493
Query: 2745 TFASSGLIYYMAHQNQADYAVLQLHGGRLHFMFDLGKGRTKVSHPALLSDGKWHTVKTDY 2804
T +S G+I+Y++ Q + D+ L L GRL +MF++G + K+ +DG WH V
Sbjct: 1494 TRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIR 1553
Query: 2805 VKRKGFITVDGRESPMVTVVGDGTMLDVEGLFYLGGLPSQYQARKIG-NITHSIPACIGD 2863
+ G + +DG ++ ++G YLGG+ + + N +S C+ +
Sbjct: 1554 ERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSN 1613
Query: 2864 VTVNSKQLDKDSPVSAFTVNRCYAVAQE-GTYFDGSGYAALVKEGYKVQSDVNITLEFRT 2922
+ +N + S F+V C+ E GTYF G ++ E + + I E R
Sbjct: 1614 LQLNGASITSAS--QTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRP 1671
Query: 2923 SSQNGVLLGISTAKVDAIGLELVDGKVLFHVNNGAGRITAAYEPKTATVLCDGKWHTLQA 2982
S +G L+ + + + + + +G+V+ VNNG + + PK + LCDG+WH +
Sbjct: 1672 RSSSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQS--LCDGRWHRITV 1729
Query: 2983 NKSKHRITLIVDGNAVGAESPHTQSTSVDTNNPIYVGGYPAGVKQKCLRSQTSFRGCLRK 3042
+ + + L VD P +D P++VGG P + L F GC+R
Sbjct: 1730 IRDSNVVQLDVDSEVNHVVGP-LNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRH 1788
Query: 3043 LALIKSPQVQSFDFSRAFELHG-VFLHSCP 3071
+ P FS+A + G V ++SCP
Sbjct: 1789 FVIDGHP----VSFSKAALVSGAVSINSCP 1814
Score = 199 bits (505), Expect = 5e-50
Identities = 103/248 (41%), Positives = 133/248 (53%), Gaps = 14/248 (5%)
Query: 691 DIASSNAIDLVVAADVEHCECPQGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAAE 750
DI S+A+ + G + E C +G++ G C PC+C+G++ E
Sbjct: 35 DIEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFHT----LSGECVPCDCNGNSNE 90
Query: 751 C-NVHGVCIACAHNTTGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLN 809
C + G C+ C NTTG HCE+CL G+ G+ RG P CQPC CPL +N F+ +C+
Sbjct: 91 CLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLAN-FAESCYRK 149
Query: 810 DGDEVVCDWCAPGYSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGH-CDSVTG 868
+G V C Y+G CERCA GYYGNP + G +C CDCSGN DP+ CD VTG
Sbjct: 150 NG--AVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTG 207
Query: 869 ECLKCLGNTDGAHCERCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNVT 928
+C CL NT G CERCA G+YGDA AKNC C C C TG C +
Sbjct: 208 QCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNC-----GGGPCDSVTGECLEEGFEP 262
Query: 929 GQQCDQCL 936
CD+C+
Sbjct: 263 PTGCDKCV 270
Score = 111 bits (277), Expect = 1e-23
Identities = 88/275 (32%), Positives = 120/275 (43%), Gaps = 47/275 (17%)
Query: 826 AWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSV-TGECLKCLGNTDGAHCER 884
A C R A G ++ P D G+ S G D T E LG A E+
Sbjct: 19 AACSRAASG--------DDNAFPFDIEGS---SAVGRQDPPETSEPRVALGRLPPA-AEK 66
Query: 885 CADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLC-DCKPNVTGQQCDQCLHGYYGLD 943
C GF+ + C C+C+ +S C +G C C+ N TG+ C++CL GY G D
Sbjct: 67 CNAGFFH--TLSGECVPCDCN---GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIG-D 120
Query: 944 SGHG----CRPCNCSV--AGSVSDGCTDEG---QCHCVPGVAGKRCDRCAHGFYAYQ--- 991
S G C+PC C + + ++ C + +C C AG C+RCA G+Y
Sbjct: 121 SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI 180
Query: 992 DGSCTPCDCPHTQN------TCDPETGEC-VCPPHTQGVKCEECEDGHWGYDAEV--GCQ 1042
+C CDC + CD TG+C C +T G KCE C G++G DA + C
Sbjct: 181 GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNCA 239
Query: 1043 ACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQC 1077
CNC CD VTG C + CD+C
Sbjct: 240 VCNCG-----GGPCDSVTGECLEEGFEPPTGCDKC 269
Score = 90.5 bits (223), Expect = 2e-17
Identities = 62/188 (32%), Positives = 78/188 (41%), Gaps = 21/188 (11%)
Query: 981 DRCAHGFYAYQDGSCTPCDCPHTQNTCDPETGECV-CPPHTQGVKCEECEDGHWG---YD 1036
++C GF+ G C PCDC N C +G CV C +T G CE+C DG+ G
Sbjct: 65 EKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRG 124
Query: 1037 AEVGCQACNCSL--VGSTHHRCDVVTG--HCQCKSKFGGRACDQCSLGYRDFP-----DC 1087
A CQ C C L + + C G C C + G C++C+ GY P C
Sbjct: 125 APQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTC 184
Query: 1088 VPCDCDLRGTSGDACNLEQGLCGCVEETGAC-PCKENVFGPQCNECREGTFALRADNPLG 1146
CDC G S E C E TG C C N G +C C G + A
Sbjct: 185 KKCDCS--GNSDPNLIFED----CDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKN 237
Query: 1147 CSPCFCSG 1154
C+ C C G
Sbjct: 238 CAVCNCGG 245
Score = 90.5 bits (223), Expect = 2e-17
Identities = 59/197 (29%), Positives = 83/197 (42%), Gaps = 43/197 (21%)
Query: 324 CEACNCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRP 383
C C+C+ + +C G G C++C +NT G +CE C+DGY
Sbjct: 79 CVPCDCNGNSNEC------------------LDGSGYCVHCQRNTTGEHCEKCLDGYIGD 120
Query: 384 H-KVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQ 442
+ +P +PC PC + + + C + NG +C C E Y G C+RC
Sbjct: 121 SIRGAPQFCQPC-PCPLPHLANFAESCYR-------KNGAV--RCICNENYAGPNCERCA 170
Query: 443 LGYKDYP-----TCVSCGC------NPVGSASDEPCTGPC-VCKENVEGKACDRCKPGFY 490
GY P TC C C N + DE TG C C N G C+RC PG+Y
Sbjct: 171 PGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDE-VTGQCRNCLRNTTGFKCERCAPGYY 229
Query: 491 NLKEKNPRGCSECFCFG 507
+ + C+ C C G
Sbjct: 230 G-DARIAKNCAVCNCGG 245
Score = 73.2 bits (178), Expect = 4e-12
Identities = 64/227 (28%), Positives = 87/227 (38%), Gaps = 50/227 (22%)
Query: 270 CICYGHASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNC 329
C C G+++ C D + + CQ NT GE C +C GY R + C+ C C
Sbjct: 82 CDCNGNSNEC-LDGSGYCVHCQ--RNTTGEHCEKCLDGYIGDSIR----GAPQFCQPCPC 134
Query: 330 -----HNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYY-RP 383
N A+ CY + G V C +N G NCE C GYY P
Sbjct: 135 PLPHLANFAESCYR-----------------KNGAVRCICNENYAGPNCERCAPGYYGNP 177
Query: 384 HKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQC-PCKEGYTGEKCDRCQ 442
+ C+ C+C G+ I +D + GQC C TG KC+RC
Sbjct: 178 LLIG----STCKKCDCS--GNSDPNLIFEDC------DEVTGQCRNCLRNTTGFKCERCA 225
Query: 443 LGY----KDYPTCVSCGCNPVGSASDEPCTGPCVCKENVEGKACDRC 485
GY + C C C G + TG C+ + CD+C
Sbjct: 226 PGYYGDARIAKNCAVCNC---GGGPCDSVTGECLEEGFEPPTGCDKC 269
>gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
Length = 1816
Score = 394 bits (1011), Expect = e-108
Identities = 426/1830 (23%), Positives = 765/1830 (41%), Gaps = 214/1830 (11%)
Query: 1383 GKLPAGSDRGP----RPLVAPCVPCSCNNHSDTCDPNTGKCLNCGDNTAGDHCDVCTSGY 1438
G+LP +++ L CVPC CN +S+ C +G C++C NT G+HC+ C GY
Sbjct: 58 GRLPPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGY 117
Query: 1439 YG-KVTGSASDCALCACPHSPPASFSPTCVLEGDHDFRCDACLLGYEGKHCERCSSSYYG 1497
G + G+ C C CP A+F+ +C + + RC C Y G +CERC+ YYG
Sbjct: 118 IGDSIRGAPQFCQPCPCPLPHLANFAESCYRK-NGAVRC-ICNENYAGPNCERCAPGYYG 175
Query: 1498 NPQTPGGSCQKCDCNPHGS---VHGDCDRTSGQC-VCRLGASGLRCDECEPRH---ILME 1550
NP G +C+KCDC+ + + DCD +GQC C +G +C+ C P + +
Sbjct: 176 NPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIA 235
Query: 1551 TDCVSCD------DECVGVLLND---------------LDEIGDAVLSL--NLTGIIPVP 1587
+C C+ D G L + D + A LS+ +G++ V
Sbjct: 236 KNCAVCNCGGGPCDSVTGECLEEGFEPPTGCDKCVWDLTDALRLAALSIEEGKSGVLSVS 295
Query: 1588 YGILS----NLENTTKYLQESLLKE-NMQKDLGKIKLEGVAEETDNLQKKLTRMLASTQK 1642
G + N N T YL ++ L E Q L KI++ +L + ++ +
Sbjct: 296 SGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKENQ 355
Query: 1643 VNRATERIFKESQDLAIAIERLQMSITEIMEK-TTLNQTL----DEDFLLPNSTLQNMQQ 1697
+R + + KES D +L ++ +K +N + +E L P + +
Sbjct: 356 ASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVL 415
Query: 1698 NGTSLLEIMQIRDFTQLHQNATLELKAAEDLLSQIQENYQKPLEELEVLKEAASHVLSKH 1757
L EI + F + E A +LLSQ E++Q+ E L L +
Sbjct: 416 AQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQ-AESWQRLHNETRTLFPVVLEQLDDY 474
Query: 1758 NNELKAAEALVREAEAKMQESNHLLLMVNANLREFSDKKLHVQEEQNLTSELIVQGRGLI 1817
N +L + EA Q N++ + N + ++ H ++++ + ++ V L
Sbjct: 475 NAKLSDLQ------EALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLS 528
Query: 1818 DAAAAQTDAVQDALEHLEDHQDKLLLWSAKIRHHIDDLVMHMSQRNAV--DLVYRAEDHA 1875
+A + T + L L+D A+I +L + +S + + DLV A DHA
Sbjct: 529 TSADSLT-TPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHA 587
Query: 1876 AEFQRLADVLYSGL--ENIRNVSLNATSAAYVHYNIQSLIEESEELARDAHRTVTETSLL 1933
+ Q+ A+ L L ++ + A A+ V+ NI + + E+ E A A T
Sbjct: 588 QDLQQEANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDA 647
Query: 1934 SESLVSNGKAAVQRSSRFLKEGNNLSRKLPGIALE-LSELRNKTNRFQENAVEITRQTNE 1992
+ + S L + L K + E +++ + + + ++
Sbjct: 648 VSGIDTQIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSD 707
Query: 1993 SLLILRAIPKG-IRDKGAKTKELATSASQSAVSTLRDVAGLSQELLNTSASLSRVNTTLR 2051
++ L+A +G + + +++ + A+++ + + A ++ L N S +L +++
Sbjct: 708 AVKQLQAAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAY 767
Query: 2052 ETHQLLQDSTMATLLAGRKVKDVEIQANLLFDRLKPL--KMLEENLSRNLSEIKLLISQA 2109
T A A V+++ L D+L+ + K N+S ++ I+ LI+Q
Sbjct: 768 NT---------AVNSARDAVRNLTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQT 818
Query: 2110 RKQAASIKVAVSADRDCIRAYQPQISSTN---YNTLTLNVK--------TQEPDNLLFYL 2158
R A+ I+V++ D + S + + +L+L +K T+ D + YL
Sbjct: 819 RSVASKIQVSMMFDGQSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYL 878
Query: 2159 GSSTA-SDFLAVEMRRGRVAFLWDLGSGSTRLEFPDFPIDDNRWHS----IHVARFGNIG 2213
GS A +++ + ++ + ++++LG+ + P+ + W + + + R G G
Sbjct: 879 GSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPV--SSWPAYFSIVKIERVGKHG 936
Query: 2214 S--LSVKEMSSN-QKSPTKTSKSPGTANVLDVN-NSTLMFVGGLGGQIKKSPAVKVTHFK 2269
L+V +SS ++ K + G ++LD++ T+ +VGG+ K ++ + F
Sbjct: 937 KVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFV 996
Query: 2270 GCLGEAFLNGKSIGLWNYIEREGK--------CRGCFGSSQNEDPSFHFDGSGYSVV--- 2318
GCL A LN I L+N+ R +Q+ S+ FDGSGY+VV
Sbjct: 997 GCLELATLNNDVISLYNFKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDI 1056
Query: 2319 -EKSLPATVTQIIMLFNTFSPNGLLLYLGSYGTKDFLSIELFRGRVKVMTDLG--SGPIT 2375
+ VT+ + T + NGL+L + F +E+ G + V D G GP+
Sbjct: 1057 TRRGKFGQVTRFDIEVRTPADNGLILLM--VNGSMFFRLEMRNGYLHVFYDFGFSGGPVH 1114
Query: 2376 L---LTDRRYNNGTWYKIAFQRNRKQGVLAVIDAYNTSNKETKQGETPGASSDLNRLDKD 2432
L L + N+ +++I+ + + ++ V+D + + + ++ + P
Sbjct: 1115 LEDTLKKAQINDAKYHEISIIYHNDKKMILVVDRRHVKSMDNEKMKIPFTD--------- 1165
Query: 2433 PIYVGGLP----RSRVVRRGVTTK-SFVGCIKNLEISRSTFDLLR--NSYGVRKGCLLEP 2485
IY+GG P +SR +R + +F GC+K + + F+LL + GV GC +
Sbjct: 1166 -IYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQKKDFNLLEQTETLGVGYGCPEDS 1224
Query: 2486 I--RSVSFLKGGYIELPPK-SLSPESEWLVTFATTNSSGIIL-AALGGDVEKRGDREEAH 2541
+ R F +I K S E F T +G++ A G DV
Sbjct: 1225 LISRRAYFNGQSFIASIQKISFFDGFEGGFNFRTLQPNGLLFYYASGSDV---------- 1274
Query: 2542 VPFFSVMLIGGNIEVHVNPGDGTGLRKALLHAPTGTCSDGQAH----SISLVRNRRII-T 2596
FS+ L G + + V G++ + + +DG +H S+S R I+
Sbjct: 1275 ---FSISLDNGTVIMDVK-----GIK---VQSVDKQYNDGLSHFVISSVSPTRYELIVDK 1323
Query: 2597 VQLDENNPVEMKLGTLVESRTINVSNLYVGGIPEGEGTSLLTMRRSFHGCIKNLIF---- 2652
++ NP + K +E + Y GG P + +F GCI N F
Sbjct: 1324 SRVGSKNPTKGK----IEQTQASEKKFYFGGSP------ISAQYANFTGCISNAYFTRVD 1373
Query: 2653 -NLELLDFNSAVGHEQVDLDTCWLS--------------ERPKLAPDAEDSKLLPEPRAF 2697
++E+ DF L C + +PK + + + K P
Sbjct: 1374 RDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWD 1433
Query: 2698 P-------------EQCVVDAALEYVPGAHQFGLTQNSHFILPFNQSAVRKKLSVELSIR 2744
P C + + + A+Q+G T NS + K + +R
Sbjct: 1434 PVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLR 1493
Query: 2745 TFASSGLIYYMAHQNQADYAVLQLHGGRLHFMFDLGKGRTKVSHPALLSDGKWHTVKTDY 2804
T +S G+I+Y++ Q + D+ L L GRL +MF++G + K+ +DG WH V
Sbjct: 1494 TRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIR 1553
Query: 2805 VKRKGFITVDGRESPMVTVVGDGTMLDVEGLFYLGGLPSQYQARKIG-NITHSIPACIGD 2863
+ G + +DG ++ ++G YLGG+ + + N +S C+ +
Sbjct: 1554 ERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSN 1613
Query: 2864 VTVNSKQLDKDSPVSAFTVNRCYAVAQE-GTYFDGSGYAALVKEGYKVQSDVNITLEFRT 2922
+ +N + S F+V C+ E GTYF G ++ E + + I E R
Sbjct: 1614 LQLNGASITSAS--QTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRP 1671
Query: 2923 SSQNGVLLGISTAKVDAIGLELVDGKVLFHVNNGAGRITAAYEPKTATVLCDGKWHTLQA 2982
S +G L+ + + + + + +G+V+ VNNG + + PK + LCDG+WH +
Sbjct: 1672 RSSSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQS--LCDGRWHRITV 1729
Query: 2983 NKSKHRITLIVDGNAVGAESPHTQSTSVDTNNPIYVGGYPAGVKQKCLRSQTSFRGCLRK 3042
+ + + L VD P +D P++VGG P + L F GC+R
Sbjct: 1730 IRDSNVVQLDVDSEVNHVVGP-LNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRH 1788
Query: 3043 LALIKSPQVQSFDFSRAFELHG-VFLHSCP 3071
+ P FS+A + G V ++SCP
Sbjct: 1789 FVIDGHP----VSFSKAALVSGAVSINSCP 1814
Score = 199 bits (505), Expect = 5e-50
Identities = 103/248 (41%), Positives = 133/248 (53%), Gaps = 14/248 (5%)
Query: 691 DIASSNAIDLVVAADVEHCECPQGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAAE 750
DI S+A+ + G + E C +G++ G C PC+C+G++ E
Sbjct: 35 DIEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFHT----LSGECVPCDCNGNSNE 90
Query: 751 C-NVHGVCIACAHNTTGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLN 809
C + G C+ C NTTG HCE+CL G+ G+ RG P CQPC CPL +N F+ +C+
Sbjct: 91 CLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLAN-FAESCYRK 149
Query: 810 DGDEVVCDWCAPGYSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGH-CDSVTG 868
+G V C Y+G CERCA GYYGNP + G +C CDCSGN DP+ CD VTG
Sbjct: 150 NG--AVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTG 207
Query: 869 ECLKCLGNTDGAHCERCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNVT 928
+C CL NT G CERCA G+YGDA AKNC C C C TG C +
Sbjct: 208 QCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNC-----GGGPCDSVTGECLEEGFEP 262
Query: 929 GQQCDQCL 936
CD+C+
Sbjct: 263 PTGCDKCV 270
Score = 111 bits (277), Expect = 1e-23
Identities = 88/275 (32%), Positives = 120/275 (43%), Gaps = 47/275 (17%)
Query: 826 AWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSV-TGECLKCLGNTDGAHCER 884
A C R A G ++ P D G+ S G D T E LG A E+
Sbjct: 19 AACSRAASG--------DDNAFPFDIEGS---SAVGRQDPPETSEPRVALGRLPPA-AEK 66
Query: 885 CADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLC-DCKPNVTGQQCDQCLHGYYGLD 943
C GF+ + C C+C+ +S C +G C C+ N TG+ C++CL GY G D
Sbjct: 67 CNAGFFH--TLSGECVPCDCN---GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIG-D 120
Query: 944 SGHG----CRPCNCSV--AGSVSDGCTDEG---QCHCVPGVAGKRCDRCAHGFYAYQ--- 991
S G C+PC C + + ++ C + +C C AG C+RCA G+Y
Sbjct: 121 SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI 180
Query: 992 DGSCTPCDCPHTQN------TCDPETGEC-VCPPHTQGVKCEECEDGHWGYDAEV--GCQ 1042
+C CDC + CD TG+C C +T G KCE C G++G DA + C
Sbjct: 181 GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNCA 239
Query: 1043 ACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQC 1077
CNC CD VTG C + CD+C
Sbjct: 240 VCNCG-----GGPCDSVTGECLEEGFEPPTGCDKC 269
Score = 90.5 bits (223), Expect = 2e-17
Identities = 62/188 (32%), Positives = 78/188 (41%), Gaps = 21/188 (11%)
Query: 981 DRCAHGFYAYQDGSCTPCDCPHTQNTCDPETGECV-CPPHTQGVKCEECEDGHWG---YD 1036
++C GF+ G C PCDC N C +G CV C +T G CE+C DG+ G
Sbjct: 65 EKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRG 124
Query: 1037 AEVGCQACNCSL--VGSTHHRCDVVTG--HCQCKSKFGGRACDQCSLGYRDFP-----DC 1087
A CQ C C L + + C G C C + G C++C+ GY P C
Sbjct: 125 APQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTC 184
Query: 1088 VPCDCDLRGTSGDACNLEQGLCGCVEETGAC-PCKENVFGPQCNECREGTFALRADNPLG 1146
CDC G S E C E TG C C N G +C C G + A
Sbjct: 185 KKCDCS--GNSDPNLIFED----CDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKN 237
Query: 1147 CSPCFCSG 1154
C+ C C G
Sbjct: 238 CAVCNCGG 245
Score = 90.5 bits (223), Expect = 2e-17
Identities = 59/197 (29%), Positives = 83/197 (42%), Gaps = 43/197 (21%)
Query: 324 CEACNCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRP 383
C C+C+ + +C G G C++C +NT G +CE C+DGY
Sbjct: 79 CVPCDCNGNSNEC------------------LDGSGYCVHCQRNTTGEHCEKCLDGYIGD 120
Query: 384 H-KVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQ 442
+ +P +PC PC + + + C + NG +C C E Y G C+RC
Sbjct: 121 SIRGAPQFCQPC-PCPLPHLANFAESCYR-------KNGAV--RCICNENYAGPNCERCA 170
Query: 443 LGYKDYP-----TCVSCGC------NPVGSASDEPCTGPC-VCKENVEGKACDRCKPGFY 490
GY P TC C C N + DE TG C C N G C+RC PG+Y
Sbjct: 171 PGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDE-VTGQCRNCLRNTTGFKCERCAPGYY 229
Query: 491 NLKEKNPRGCSECFCFG 507
+ + C+ C C G
Sbjct: 230 G-DARIAKNCAVCNCGG 245
Score = 73.2 bits (178), Expect = 4e-12
Identities = 64/227 (28%), Positives = 87/227 (38%), Gaps = 50/227 (22%)
Query: 270 CICYGHASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNC 329
C C G+++ C D + + CQ NT GE C +C GY R + C+ C C
Sbjct: 82 CDCNGNSNEC-LDGSGYCVHCQ--RNTTGEHCEKCLDGYIGDSIR----GAPQFCQPCPC 134
Query: 330 -----HNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYY-RP 383
N A+ CY + G V C +N G NCE C GYY P
Sbjct: 135 PLPHLANFAESCYR-----------------KNGAVRCICNENYAGPNCERCAPGYYGNP 177
Query: 384 HKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQC-PCKEGYTGEKCDRCQ 442
+ C+ C+C G+ I +D + GQC C TG KC+RC
Sbjct: 178 LLIG----STCKKCDCS--GNSDPNLIFEDC------DEVTGQCRNCLRNTTGFKCERCA 225
Query: 443 LGY----KDYPTCVSCGCNPVGSASDEPCTGPCVCKENVEGKACDRC 485
GY + C C C G + TG C+ + CD+C
Sbjct: 226 PGYYGDARIAKNCAVCNC---GGGPCDSVTGECLEEGFEPPTGCDKC 269
>gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens]
Length = 1823
Score = 391 bits (1004), Expect = e-108
Identities = 426/1837 (23%), Positives = 765/1837 (41%), Gaps = 221/1837 (12%)
Query: 1383 GKLPAGSDRGP----RPLVAPCVPCSCNNHSDTCDPNTGKCLNCGDNTAGDHCDVCTSGY 1438
G+LP +++ L CVPC CN +S+ C +G C++C NT G+HC+ C GY
Sbjct: 58 GRLPPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGY 117
Query: 1439 YG-KVTGSASDCALCACPHSPPASFSPTCVLEGDHDFRCDACLLGYEGKHCERCSSSYYG 1497
G + G+ C C CP A+F+ +C + + RC C Y G +CERC+ YYG
Sbjct: 118 IGDSIRGAPQFCQPCPCPLPHLANFAESCYRK-NGAVRC-ICNENYAGPNCERCAPGYYG 175
Query: 1498 NPQTPGGSCQKCDCNPHGS---VHGDCDRTSGQC-VCRLGASGLRCDECEPRH---ILME 1550
NP G +C+KCDC+ + + DCD +GQC C +G +C+ C P + +
Sbjct: 176 NPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIA 235
Query: 1551 TDCVSCD------DECVGVLLND----------------------LDEIGDAVLSL--NL 1580
+C C+ D G L + D + A LS+
Sbjct: 236 KNCAVCNCGGGPCDSVTGECLEEGFEPPTGMDCPTISCDKCVWDLTDALRLAALSIEEGK 295
Query: 1581 TGIIPVPYGILS----NLENTTKYLQESLLKE-NMQKDLGKIKLEGVAEETDNLQKKLTR 1635
+G++ V G + N N T YL ++ L E Q L KI++ +L +
Sbjct: 296 SGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEE 355
Query: 1636 MLASTQKVNRATERIFKESQDLAIAIERLQMSITEIMEK-TTLNQTL----DEDFLLPNS 1690
++ + +R + + KES D +L ++ +K +N + +E L P
Sbjct: 356 LVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKE 415
Query: 1691 TLQNMQQNGTSLLEIMQIRDFTQLHQNATLELKAAEDLLSQIQENYQKPLEELEVLKEAA 1750
+ + L EI + F + E A +LLSQ E++Q+ E L
Sbjct: 416 ISEKLVLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQ-AESWQRLHNETRTLFPVV 474
Query: 1751 SHVLSKHNNELKAAEALVREAEAKMQESNHLLLMVNANLREFSDKKLHVQEEQNLTSELI 1810
L +N +L + EA Q N++ + N + ++ H ++++ + ++
Sbjct: 475 LEQLDDYNAKLSDLQ------EALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQME 528
Query: 1811 VQGRGLIDAAAAQTDAVQDALEHLEDHQDKLLLWSAKIRHHIDDLVMHMSQRNAV--DLV 1868
V L +A + T + L L+D A+I +L + +S + + DLV
Sbjct: 529 VVNMSLSTSADSLT-TPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLV 587
Query: 1869 YRAEDHAAEFQRLADVLYSGL--ENIRNVSLNATSAAYVHYNIQSLIEESEELARDAHRT 1926
A DHA + Q+ A+ L L ++ + A A+ V+ NI + + E+ E A A T
Sbjct: 588 QEAIDHAQDLQQEANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNT 647
Query: 1927 VTETSLLSESLVSNGKAAVQRSSRFLKEGNNLSRKLPGIALE-LSELRNKTNRFQENAVE 1985
+ + S L + L K + E +++ +
Sbjct: 648 TDRIYDAVSGIDTQIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSA 707
Query: 1986 ITRQTNESLLILRAIPKG-IRDKGAKTKELATSASQSAVSTLRDVAGLSQELLNTSASLS 2044
+ + ++++ L+A +G + + +++ + A+++ + + A ++ L N S +L
Sbjct: 708 LKTRLSDAVKQLQAAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQ 767
Query: 2045 RVNTTLRETHQLLQDSTMATLLAGRKVKDVEIQANLLFDRLKPL--KMLEENLSRNLSEI 2102
+++ T A A V+++ L D+L+ + K N+S ++ I
Sbjct: 768 HFDSSAYNT---------AVNSARDAVRNLTEVVPQLLDQLRTVEQKRPASNVSASIQRI 818
Query: 2103 KLLISQARKQAASIKVAVSADRDCIRAYQPQISSTN---YNTLTLNVK--------TQEP 2151
+ LI+Q R A+ I+V++ D + S + + +L+L +K T+
Sbjct: 819 RELIAQTRSVASKIQVSMMFDGQSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETA 878
Query: 2152 DNLLFYLGSSTA-SDFLAVEMRRGRVAFLWDLGSGSTRLEFPDFPIDDNRWHS----IHV 2206
D + YLGS A +++ + ++ + ++++LG+ + P+ + W + + +
Sbjct: 879 DQFILYLGSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPV--SSWPAYFSIVKI 936
Query: 2207 ARFGNIGS--LSVKEMSSN-QKSPTKTSKSPGTANVLDVN-NSTLMFVGGLGGQIKKSPA 2262
R G G L+V +SS ++ K + G ++LD++ T+ +VGG+ K +
Sbjct: 937 ERVGKHGKVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTS 996
Query: 2263 VKVTHFKGCLGEAFLNGKSIGLWNYIEREGK--------CRGCFGSSQNEDPSFHFDGSG 2314
+ + F GCL A LN I L+N+ R +Q+ S+ FDGSG
Sbjct: 997 LNLPGFVGCLELATLNNDVISLYNFKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSG 1056
Query: 2315 YSVV----EKSLPATVTQIIMLFNTFSPNGLLLYLGSYGTKDFLSIELFRGRVKVMTDLG 2370
Y+VV + VT+ + T + NGL+L + F +E+ G + V D G
Sbjct: 1057 YAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLM--VNGSMFFRLEMRNGYLHVFYDFG 1114
Query: 2371 --SGPITL---LTDRRYNNGTWYKIAFQRNRKQGVLAVIDAYNTSNKETKQGETPGASSD 2425
GP+ L L + N+ +++I+ + + ++ V+D + + + ++ + P
Sbjct: 1115 FSGGPVHLEDTLKKAQINDAKYHEISIIYHNDKKMILVVDRRHVKSMDNEKMKIPFTD-- 1172
Query: 2426 LNRLDKDPIYVGGLP----RSRVVRRGVTTK-SFVGCIKNLEISRSTFDLLR--NSYGVR 2478
IY+GG P +SR +R + +F GC+K + + F+LL + GV
Sbjct: 1173 --------IYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQKKDFNLLEQTETLGVG 1224
Query: 2479 KGCLLEPI--RSVSFLKGGYIELPPK-SLSPESEWLVTFATTNSSGIIL-AALGGDVEKR 2534
GC + + R F +I K S E F T +G++ A G DV
Sbjct: 1225 YGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGGFNFRTLQPNGLLFYYASGSDV--- 1281
Query: 2535 GDREEAHVPFFSVMLIGGNIEVHVNPGDGTGLRKALLHAPTGTCSDGQAH----SISLVR 2590
FS+ L G + + V G++ + + +DG +H S+S R
Sbjct: 1282 ----------FSISLDNGTVIMDVK-----GIK---VQSVDKQYNDGLSHFVISSVSPTR 1323
Query: 2591 NRRII-TVQLDENNPVEMKLGTLVESRTINVSNLYVGGIPEGEGTSLLTMRRSFHGCIKN 2649
I+ ++ NP + K +E + Y GG P + +F GCI N
Sbjct: 1324 YELIVDKSRVGSKNPTKGK----IEQTQASEKKFYFGGSP------ISAQYANFTGCISN 1373
Query: 2650 LIF-----NLELLDFNSAVGHEQVDLDTCWLS--------------ERPKLAPDAEDSKL 2690
F ++E+ DF L C + +PK + + + K
Sbjct: 1374 AYFTRVDRDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKS 1433
Query: 2691 LPEPRAFP-------------EQCVVDAALEYVPGAHQFGLTQNSHFILPFNQSAVRKKL 2737
P P C + + + A+Q+G T NS + K
Sbjct: 1434 KDAPSWDPVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKS 1493
Query: 2738 SVELSIRTFASSGLIYYMAHQNQADYAVLQLHGGRLHFMFDLGKGRTKVSHPALLSDGKW 2797
+ +RT +S G+I+Y++ Q + D+ L L GRL +MF++G + K+ +DG W
Sbjct: 1494 QFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLW 1553
Query: 2798 HTVKTDYVKRKGFITVDGRESPMVTVVGDGTMLDVEGLFYLGGLPSQYQARKIG-NITHS 2856
H V + G + +DG ++ ++G YLGG+ + + N +S
Sbjct: 1554 HDVIFIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYS 1613
Query: 2857 IPACIGDVTVNSKQLDKDSPVSAFTVNRCYAVAQE-GTYFDGSGYAALVKEGYKVQSDVN 2915
C+ ++ +N + S F+V C+ E GTYF G ++ E + +
Sbjct: 1614 FSGCLSNLQLNGASITSAS--QTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFE 1671
Query: 2916 ITLEFRTSSQNGVLLGISTAKVDAIGLELVDGKVLFHVNNGAGRITAAYEPKTATVLCDG 2975
I E R S +G L+ + + + + + +G+V+ VNNG + + PK + LCDG
Sbjct: 1672 IAFEVRPRSSSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQS--LCDG 1729
Query: 2976 KWHTLQANKSKHRITLIVDGNAVGAESPHTQSTSVDTNNPIYVGGYPAGVKQKCLRSQTS 3035
+WH + + + + L VD P +D P++VGG P + L
Sbjct: 1730 RWHRITVIRDSNVVQLDVDSEVNHVVGP-LNPKPIDHREPVFVGGVPESLLTPRLAPSKP 1788
Query: 3036 FRGCLRKLALIKSPQVQSFDFSRAFELHG-VFLHSCP 3071
F GC+R + P FS+A + G V ++SCP
Sbjct: 1789 FTGCIRHFVIDGHP----VSFSKAALVSGAVSINSCP 1821
Score = 198 bits (503), Expect = 8e-50
Identities = 106/259 (40%), Positives = 137/259 (52%), Gaps = 29/259 (11%)
Query: 691 DIASSNAIDLVVAADVEHCECPQGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAAE 750
DI S+A+ + G + E C +G++ G C PC+C+G++ E
Sbjct: 35 DIEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFHT----LSGECVPCDCNGNSNE 90
Query: 751 C-NVHGVCIACAHNTTGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLN 809
C + G C+ C NTTG HCE+CL G+ G+ RG P CQPC CPL +N F+ +C+
Sbjct: 91 CLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLAN-FAESCYRK 149
Query: 810 DGDEVVCDWCAPGYSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGH-CDSVTG 868
+G V C Y+G CERCA GYYGNP + G +C CDCSGN DP+ CD VTG
Sbjct: 150 NG--AVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTG 207
Query: 869 ECLKCLGNTDGAHCERCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLC------- 921
+C CL NT G CERCA G+YGDA AKNC C C C TG C
Sbjct: 208 QCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNC-----GGGPCDSVTGECLEEGFEP 262
Query: 922 ----DCKPNVTGQQCDQCL 936
DC P ++ CD+C+
Sbjct: 263 PTGMDC-PTIS---CDKCV 277
Score = 107 bits (268), Expect = 1e-22
Identities = 85/261 (32%), Positives = 115/261 (44%), Gaps = 47/261 (18%)
Query: 826 AWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSV-TGECLKCLGNTDGAHCER 884
A C R A G ++ P D G+ S G D T E LG A E+
Sbjct: 19 AACSRAASG--------DDNAFPFDIEGS---SAVGRQDPPETSEPRVALGRLPPA-AEK 66
Query: 885 CADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLC-DCKPNVTGQQCDQCLHGYYGLD 943
C GF+ + C C+C+ +S C +G C C+ N TG+ C++CL GY G D
Sbjct: 67 CNAGFFH--TLSGECVPCDCN---GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIG-D 120
Query: 944 SGHG----CRPCNCSV--AGSVSDGCTDEG---QCHCVPGVAGKRCDRCAHGFYAYQ--- 991
S G C+PC C + + ++ C + +C C AG C+RCA G+Y
Sbjct: 121 SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI 180
Query: 992 DGSCTPCDCPHTQN------TCDPETGEC-VCPPHTQGVKCEECEDGHWGYDAEV--GCQ 1042
+C CDC + CD TG+C C +T G KCE C G++G DA + C
Sbjct: 181 GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNCA 239
Query: 1043 ACNCSLVGSTHHRCDVVTGHC 1063
CNC CD VTG C
Sbjct: 240 VCNCG-----GGPCDSVTGEC 255
Score = 90.5 bits (223), Expect = 2e-17
Identities = 62/188 (32%), Positives = 78/188 (41%), Gaps = 21/188 (11%)
Query: 981 DRCAHGFYAYQDGSCTPCDCPHTQNTCDPETGECV-CPPHTQGVKCEECEDGHWG---YD 1036
++C GF+ G C PCDC N C +G CV C +T G CE+C DG+ G
Sbjct: 65 EKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRG 124
Query: 1037 AEVGCQACNCSL--VGSTHHRCDVVTG--HCQCKSKFGGRACDQCSLGYRDFP-----DC 1087
A CQ C C L + + C G C C + G C++C+ GY P C
Sbjct: 125 APQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTC 184
Query: 1088 VPCDCDLRGTSGDACNLEQGLCGCVEETGAC-PCKENVFGPQCNECREGTFALRADNPLG 1146
CDC G S E C E TG C C N G +C C G + A
Sbjct: 185 KKCDCS--GNSDPNLIFED----CDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKN 237
Query: 1147 CSPCFCSG 1154
C+ C C G
Sbjct: 238 CAVCNCGG 245
Score = 90.5 bits (223), Expect = 2e-17
Identities = 59/197 (29%), Positives = 83/197 (42%), Gaps = 43/197 (21%)
Query: 324 CEACNCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRP 383
C C+C+ + +C G G C++C +NT G +CE C+DGY
Sbjct: 79 CVPCDCNGNSNEC------------------LDGSGYCVHCQRNTTGEHCEKCLDGYIGD 120
Query: 384 H-KVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQ 442
+ +P +PC PC + + + C + NG +C C E Y G C+RC
Sbjct: 121 SIRGAPQFCQPC-PCPLPHLANFAESCYR-------KNGAV--RCICNENYAGPNCERCA 170
Query: 443 LGYKDYP-----TCVSCGC------NPVGSASDEPCTGPC-VCKENVEGKACDRCKPGFY 490
GY P TC C C N + DE TG C C N G C+RC PG+Y
Sbjct: 171 PGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDE-VTGQCRNCLRNTTGFKCERCAPGYY 229
Query: 491 NLKEKNPRGCSECFCFG 507
+ + C+ C C G
Sbjct: 230 G-DARIAKNCAVCNCGG 245
Score = 72.4 bits (176), Expect = 6e-12
Identities = 41/133 (30%), Positives = 61/133 (45%), Gaps = 35/133 (26%)
Query: 288 LQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKA------KDCYYDES 341
++C C N G +C RC PGY+ P + G+TC+ C+C + +DC DE
Sbjct: 153 VRCICNENYAGPNCERCAPGYYGNP-----LLIGSTCKKCDCSGNSDPNLIFEDC--DEV 205
Query: 342 VAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNC-- 399
G C NCL+NT G CE C GYY +++ + C CNC
Sbjct: 206 T----------------GQCRNCLRNTTGFKCERCAPGYYGDARIA----KNCAVCNCGG 245
Query: 400 DPVGSLSSVCIKD 412
P S++ C+++
Sbjct: 246 GPCDSVTGECLEE 258
Score = 69.7 bits (169), Expect = 4e-11
Identities = 66/235 (28%), Positives = 90/235 (38%), Gaps = 59/235 (25%)
Query: 270 CICYGHASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNC 329
C C G+++ C D + + CQ NT GE C +C GY R + C+ C C
Sbjct: 82 CDCNGNSNEC-LDGSGYCVHCQ--RNTTGEHCEKCLDGYIGDSIR----GAPQFCQPCPC 134
Query: 330 -----HNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYY-RP 383
N A+ CY + G V C +N G NCE C GYY P
Sbjct: 135 PLPHLANFAESCYR-----------------KNGAVRCICNENYAGPNCERCAPGYYGNP 177
Query: 384 HKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQC-PCKEGYTGEKCDRCQ 442
+ C+ C+C G+ I +D + GQC C TG KC+RC
Sbjct: 178 LLIG----STCKKCDCS--GNSDPNLIFEDC------DEVTGQCRNCLRNTTGFKCERCA 225
Query: 443 LGY----KDYPTCVSCGCNPVGSASDEPCTGPCVCKENVEGK--------ACDRC 485
GY + C C C G + TG C+ +E E +CD+C
Sbjct: 226 PGYYGDARIAKNCAVCNC---GGGPCDSVTGECL-EEGFEPPTGMDCPTISCDKC 276
>gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens]
Length = 1668
Score = 386 bits (991), Expect = e-106
Identities = 442/1780 (24%), Positives = 729/1780 (40%), Gaps = 252/1780 (14%)
Query: 1374 QDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKCLNCGDNTAGDHCDV 1433
Q C+PGY+R + R CVPC+CN HS+ C +G C+NC NTAG+HC+
Sbjct: 57 QGCSPGYYRDHKGLYTGR--------CVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCER 108
Query: 1434 CTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGDHDFRCDACLLGYEGKHCERCSS 1493
C GYYG + C C CPH+ SF+ CV+ G D RC +C GY G CERC+
Sbjct: 109 CQEGYYGNAVHGS--CRACPCPHTN--SFATGCVVNGG-DVRC-SCKAGYTGTQCERCAP 162
Query: 1494 SYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDECEPRHILMETDC 1553
Y+GNPQ GGSCQ C CN +G + G C +G C+ + +EC+ DC
Sbjct: 163 GYFGNPQKFGGSCQPCSCNSNGQL-GSCHPLTGDCINQEPKDSSPAEECD--------DC 213
Query: 1554 VSCDDECVGVLLNDLDEIGDAV--LSLNLTGIIPVPYGILS---NLENTTKYLQESLLKE 1608
D CV LLNDL +G+ + + L G+ G+L ++E K L+ LL
Sbjct: 214 ----DSCVMTLLNDLATMGEQLRLVKSQLQGL-SASAGLLEQMRHMETQAKDLRNQLLNY 268
Query: 1609 NMQKDLGKIKLEGVAEETDNLQKKLTRMLASTQKVNRATERIFKESQDLAIAIERLQMSI 1668
K+EG+ E +L ++ + Q +R ++Q L + R S
Sbjct: 269 RSAISNHGSKIEGLERELTDLNQEFETLQEKAQVNSR-------KAQTLNNNVNRATQSA 321
Query: 1669 TEIMEKTTLNQTLDEDFLLPNSTLQNMQQNGTSLLEIMQIRDFTQLHQNATLELKAAEDL 1728
E+ K + ++N+ + +IR + + HQ L A +
Sbjct: 322 KELDVKI-------------KNVIRNVHM-------LNRIRTWQKTHQGENNGL--ANSI 359
Query: 1729 LSQIQENYQKPLEELEVLKEAASHVLSKHNNELKAAEALVREAEAKMQESNHLLLMVNAN 1788
+ E Y+ L +L L+ A A ++A QE+ L +
Sbjct: 360 RDSLNE-YEAKLSDLRA--------------RLQEAAAQAKQANGLNQENERALGAIQRQ 404
Query: 1789 LREFSDKKLHVQEEQNLTSELIVQGRGLIDAAAAQTDAVQDALEHLEDHQDKLLLWSAKI 1848
++E + + + T L D++ QT+ +E + +KL +
Sbjct: 405 VKEINSL------QSDFTKYLTTA-----DSSLLQTNIALQLMEKSQKEYEKLAASLNEA 453
Query: 1849 RHHIDDLVMHMSQR-NAVDLVYRAEDHAAEFQRLADVLYSGLENIRNVSLN--ATSAAYV 1905
R + D V +S+ LV AE HA Q LA L N L A AA
Sbjct: 454 RQELSDKVRELSRSAGKTSLVEEAEKHARSLQELAKQLEEIKRNASGDELVRCAVDAATA 513
Query: 1906 HYNIQSLIEESEELARDAHRTVTETSL---LSESLVSNGKAAVQRSSRFLKEGNNLSRKL 1962
+ NI + I+ +E+ A A + +E++L + E L K S + L E +KL
Sbjct: 514 YENILNAIKAAEDAANRA-ASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKL 572
Query: 1963 PGIALELSELRNKTNRFQENAVEITRQTNESLLILRAIPKGIRDKGAKTKELATSASQSA 2022
E+ N Q+ +T Q L + G+ + S+++S
Sbjct: 573 K------QEVSPALNNLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSM 626
Query: 2023 VSTLRDVAGLSQELLNT-SASLSRVNTTLRETH-----QLLQDSTMATLLAGRKVKDVEI 2076
V D+ + LN + R+ T T + L D+ + K+ D+
Sbjct: 627 VRKANDITDEVLDGLNPIQTDVERIKDTYGRTQNEDFKKALTDADNSVNKLTNKLPDLWR 686
Query: 2077 QANLLFDRLKPLKMLEENLSRNLSEIKLLISQARKQAASIKVAVSAD-RDCIRAYQPQIS 2135
+ + +L PL N+S N+ I+ LI QAR A+ + V + + + + P
Sbjct: 687 KIESINQQLLPLG----NISDNMDRIRELIQQARDAASKVAVPMRFNGKSGVEVRLPNDL 742
Query: 2136 STNYNTLTLNVKTQEPDN---------LLFYLGSSTAS-DFLAVEMRRGRVAFLWDLGSG 2185
+L++ Q P++ + YLG+ AS D++ + + G++ +++LG
Sbjct: 743 EDLKGYTSLSLFLQRPNSRENGGTENMFVMYLGNKDASRDYIGMAVVDGQLTCVYNLGDR 802
Query: 2186 STRLEFPDFPIDDNRWHSIHVARFGNIGSLSVKEMSSNQKSPTKTSKSPGTANVLDV--- 2242
L+ ++ + + + + + TS P T V D+
Sbjct: 803 EAELQVDQILTKSETKEAV----MDRVKFQRIYQFARLNYTKGATSSKPETPGVYDMDGR 858
Query: 2243 NNSTLM---------FVGGLGGQIKKSPAVKVTHFKGCLGEAFLNGKSIGLWNYIE---- 2289
N++TL+ +VGG K + +KGC+ LN + L+N+ +
Sbjct: 859 NSNTLLNLDPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELDDLNENVLSLYNFKKTFNL 918
Query: 2290 REGKCRGCFGSSQNEDPSFHFDGSGYSVVEKSLPATVTQIIMLFNTFSPNGLLLYLGSYG 2349
+ C + D ++ F+G+GY+ V A + T GLL + + G
Sbjct: 919 NTTEVEPCRRRKEESDKNY-FEGTGYARVPTQPHAPIPTFGQTIQTTVDRGLLFFAEN-G 976
Query: 2350 TKDFLSIELFRGRVKVMTDLGSG-PITLLTDRRYNNGTWYKIAFQRNRKQGVLAV-IDAY 2407
+ F+S+ + G++ V L S P NNG + I + + Q + + +D
Sbjct: 977 DR-FISLNIEDGKLMVRYKLNSELPKERGVGDAINNGRDHSIQIKIGKLQKRMWINVDVQ 1035
Query: 2408 NTSNKETKQGETPGASSDLNRLDKDPIYVGGLPRSRVVRRGVTTKSFVGCIKNLEISRST 2467
NT GE D Y+GG+P + R ++T +F GC+KNL+ S
Sbjct: 1036 NT----IIDGEV---------FDFSTYYLGGIPIAIRERFNISTPAFRGCMKNLK-KTSG 1081
Query: 2468 FDLLRNSYGVRKGCLLE--PIRSVSFLKGGYIELPPKSLSPESEWLVTFA--TTNSSGII 2523
L ++ GV K C + +RS SF +GG + L P +F T SGI+
Sbjct: 1082 VVRLNDTVGVTKKCSEDWKLVRSASFSRGGQLSFTDLGLPPTDHLQASFGFQTFQPSGIL 1141
Query: 2524 LAALGGDVEKRGDREEAHVPFFSVMLIGGNIEVHVNPGDGTGLRKALLHAPTGTCSDGQA 2583
L + V L G IE+ + G+ + K+ T DG
Sbjct: 1142 LD------------HQTWTRNLQVTLEDGYIELSTSDS-GSPIFKS-----PQTYMDGLL 1183
Query: 2584 HSISLVRN----RRIITVQLDENNPVEMKLGTLVESRTINVSNLYVGGIPEGEGTSLLTM 2639
H +S++ + R +I QL N+ +L + SR +L +GG
Sbjct: 1184 HYVSVISDNSGLRLLIDDQLLRNSK---RLKHISSSR----QSLRLGG------------ 1224
Query: 2640 RRSFHGCIKN-----LIFNLELLDFNSAVGHEQVDLDTCWLSERPKL-----------AP 2683
+F GCI N L + E+LD S V L C L++ P L
Sbjct: 1225 -SNFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLGGCSLNKPPFLMLLKGSTRFNKTK 1283
Query: 2684 DAEDSKLLPE-PRAFPEQCVV-DAALEYVP------GAHQFGLTQNSHFILPFNQSAVRK 2735
++LL + P A P V A +P GA QFG SH + Q ++
Sbjct: 1284 TFRINQLLQDTPVASPRSVKVWQDACSPLPKTQANHGALQFGDIPTSHLLFKLPQELLKP 1343
Query: 2736 KLSVELSIRTFASSGLIYYMAHQNQADYAVLQLHGGRLHFMFDLGKGRTKVSHPALLSDG 2795
+ + ++T +S GL+++ +N + L L GRL F + ++ +DG
Sbjct: 1344 RSQFAVDMQTTSSRGLVFHTGTKNS--FMALYLSKGRLVFALGTDGKKLRIKSKEKCNDG 1401
Query: 2796 KWHTVKTDYVKRKGFITVDGRESPMVTVVGDGTMLDVEGLFYLGGLPSQYQARKIGNITH 2855
KWHTV + KG + VDG + ++ G+ T + + YLG PS + T+
Sbjct: 1402 KWHTVVFGHDGEKGRLVVDGLRAREGSLPGNST-ISIRAPVYLGSPPS---GKPKSLPTN 1457
Query: 2856 SIPACIGDVTVNSKQLDKDSPVSAFTVNRCY-AVAQEGTYFDGSGYAALVKEGYKVQSDV 2914
S C+ + ++SK L +P S+F V+ C ++G YF G ++ + +
Sbjct: 1458 SFVGCLKNFQLDSKPL--YTPSSSFGVSSCLGGPLEKGIYFSEEGGHVVLAHSVLLGPEF 1515
Query: 2915 NITLEFRTSSQNGVLLGISTAKVDAIGLELVDGKVLFHVNNGAGRITAAYEPKTATVLCD 2974
+ R S G+L+ I + + + L GKV +++GAG + + PK + LCD
Sbjct: 1516 KLVFSIRPRSLTGILIHIGSQPGKHLCVYLEAGKVTASMDSGAGGTSTSVTPKQS--LCD 1573
Query: 2975 GKWHTLQANKSKH--RITLIVDGNAVGAESPHTQSTSVDTNNPIYVGGYPAGVKQKCLRS 3032
G+WH++ +H + L D + + P ++ T P+++GG PA + +
Sbjct: 1574 GQWHSVAVTIKQHILHLELDTDSSYTAGQIPFPPAS---TQEPLHLGGAPANLTTLRIPV 1630
Query: 3033 QTSFRGCLRKLALIKSPQVQSFDFSRAFELHG-VFLHSCP 3071
SF GCLR + + P + A E+ G V L+ CP
Sbjct: 1631 WKSFFGCLRNIHVNHIP----VPVTEALEVQGPVSLNGCP 1666
Score = 145 bits (365), Expect = 8e-34
Identities = 72/168 (42%), Positives = 95/168 (56%), Gaps = 13/168 (7%)
Query: 721 ESCLSGYYRVDGILFGGICQPCECHGHAAEC-NVHGVCIACAHNTTGVHCEQCLPGFYGE 779
+ C GYYR L+ G C PC C+GH+ +C + G+C+ C HNT G HCE+C G+YG
Sbjct: 57 QGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGN 116
Query: 780 PSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNP 839
G+ C+ C CP T N+F+ C +N GD V C C GY+G CERCA GY+GNP
Sbjct: 117 AVHGS---CRACPCPHT---NSFATGCVVNGGD-VRCS-CKAGYTGTQCERCAPGYFGNP 168
Query: 840 TVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCAD 887
G SC PC C+ N + G C +TG+C+ D + E C D
Sbjct: 169 QKFGGSCQPCSCNSN---GQLGSCHPLTGDCIN-QEPKDSSPAEECDD 212
Score = 108 bits (270), Expect = 8e-23
Identities = 56/149 (37%), Positives = 79/149 (53%), Gaps = 18/149 (12%)
Query: 831 CADGYY-GNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCADGF 889
C+ GYY + + CVPC+C+G+ + C +G C+ C NT G HCERC +G+
Sbjct: 59 CSPGYYRDHKGLYTGRCVPCNCNGH-----SNQCQDGSGICVNCQHNTAGEHCERCQEGY 113
Query: 890 YGDAVTAKNCRACECHVKGSHSAVCHLETG--LCDCKPNVTGQQCDQCLHGYYGLDS--G 945
YG+AV +CRAC C S + C + G C CK TG QC++C GY+G G
Sbjct: 114 YGNAVHG-SCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFG 172
Query: 946 HGCRPCNCSVAGSVSDGCTDEGQCHCVPG 974
C+PC+C+ G + G CH + G
Sbjct: 173 GSCQPCSCNSNGQL-------GSCHPLTG 194
Score = 103 bits (256), Expect = 3e-21
Identities = 53/155 (34%), Positives = 73/155 (47%), Gaps = 10/155 (6%)
Query: 885 CADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLC-DCKPNVTGQQCDQCLHGYYGLD 943
C+ G+Y D R C+ G HS C +G+C +C+ N G+ C++C GYYG
Sbjct: 59 CSPGYYRDHKGLYTGRCVPCNCNG-HSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNA 117
Query: 944 SGHGCRPCNCSVAGSVSDGCTDEG---QCHCVPGVAGKRCDRCAHGFYAYQD---GSCTP 997
CR C C S + GC G +C C G G +C+RCA G++ GSC P
Sbjct: 118 VHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQP 177
Query: 998 CDCPHT--QNTCDPETGECVCPPHTQGVKCEECED 1030
C C +C P TG+C+ EEC+D
Sbjct: 178 CSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDD 212
Score = 92.0 bits (227), Expect = 8e-18
Identities = 57/188 (30%), Positives = 77/188 (40%), Gaps = 42/188 (22%)
Query: 304 CCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCIN 363
C PGY++ G + C CNC+ + C G G+C+N
Sbjct: 59 CSPGYYRD--HKGLYTG--RCVPCNCNGHSNQCQ------------------DGSGICVN 96
Query: 364 CLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQ 423
C NT G +CE C +GYY CR C C S ++ C+ NG
Sbjct: 97 CQHNTAGEHCERCQEGYY-----GNAVHGSCRACPCPHTNSFATGCVV--------NGGD 143
Query: 424 PGQCPCKEGYTGEKCDRCQLGYKDYP-----TCVSCGCNPVGS-ASDEPCTGPCVCKENV 477
+C CK GYTG +C+RC GY P +C C CN G S P TG C+ +E
Sbjct: 144 V-RCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPK 202
Query: 478 EGKACDRC 485
+ + C
Sbjct: 203 DSSPAEEC 210
Score = 90.5 bits (223), Expect = 2e-17
Identities = 54/172 (31%), Positives = 76/172 (44%), Gaps = 19/172 (11%)
Query: 983 CAHGFY----AYQDGSCTPCDCPHTQNTCDPETGECV-CPPHTQGVKCEECEDGHWGYDA 1037
C+ G+Y G C PC+C N C +G CV C +T G CE C++G++G
Sbjct: 59 CSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAV 118
Query: 1038 EVGCQACNCSLVGSTHHRCDVVTG--HCQCKSKFGGRACDQCSLGYRDFP-----DCVPC 1090
C+AC C S C V G C CK+ + G C++C+ GY P C PC
Sbjct: 119 HGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPC 178
Query: 1091 DCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFALRAD 1142
C+ G G +C+ G C E + P +E C++C L D
Sbjct: 179 SCNSNGQLG-SCHPLTGDCINQEPKDSSPAEE------CDDCDSCVMTLLND 223
Score = 70.9 bits (172), Expect = 2e-11
Identities = 55/188 (29%), Positives = 71/188 (37%), Gaps = 37/188 (19%)
Query: 257 YYYSIKDISVGGM--CICYGHASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWR 314
YY K + G C C GH++ C + + C+HNT GE C RC GY+
Sbjct: 63 YYRDHKGLYTGRCVPCNCNGHSNQC---QDGSGICVNCQHNTAGEHCERCQEGYY----- 114
Query: 315 PGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCE 374
G G +C AC C S T GG V +C G CE
Sbjct: 115 -GNAVHG-SCRACPC--------------PHTNSFATGCVVNGGDVRCSCKAGYTGTQCE 158
Query: 375 TCIDGYY-RPHKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGY 433
C GY+ P K C+PC+C+ G L S L D N + P +E
Sbjct: 159 RCAPGYFGNPQKFG----GSCQPCSCNSNGQLGSC---HPLTGDCINQEPKDSSPAEE-- 209
Query: 434 TGEKCDRC 441
+ CD C
Sbjct: 210 -CDDCDSC 216
Score = 69.7 bits (169), Expect = 4e-11
Identities = 40/107 (37%), Positives = 50/107 (46%), Gaps = 13/107 (12%)
Query: 711 CPQGYTGTSCESCLSGYYRVDGILFGGICQPCEC---HGHAAECNVHG--VCIACAHNTT 765
C G CE C GYY G G C+ C C + A C V+G V +C T
Sbjct: 97 CQHNTAGEHCERCQEGYY---GNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYT 153
Query: 766 GVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGD 812
G CE+C PG++G P + G CQPC+C SN +CH GD
Sbjct: 154 GTQCERCAPGYFGNPQK-FGGSCQPCSC----NSNGQLGSCHPLTGD 195
Score = 63.9 bits (154), Expect = 2e-09
Identities = 41/141 (29%), Positives = 55/141 (39%), Gaps = 30/141 (21%)
Query: 376 CIDGYYRPHKVSPYEDEPCRPCNCDPVGSL----SSVCIKDDLHSDLHNGKQPGQCPCKE 431
C GYYR HK Y C PCNC+ + S +C+ C+
Sbjct: 59 CSPGYYRDHK-GLYTGR-CVPCNCNGHSNQCQDGSGICVN-----------------CQH 99
Query: 432 GYTGEKCDRCQLGYKD---YPTCVSCGCNPVGSASDEPCTGP----CVCKENVEGKACDR 484
GE C+RCQ GY + +C +C C S + C CK G C+R
Sbjct: 100 NTAGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCER 159
Query: 485 CKPGFYNLKEKNPRGCSECFC 505
C PG++ +K C C C
Sbjct: 160 CAPGYFGNPQKFGGSCQPCSC 180
Score = 54.7 bits (130), Expect = 1e-06
Identities = 38/109 (34%), Positives = 50/109 (45%), Gaps = 18/109 (16%)
Query: 694 SSNAIDLVVAADVEHCECPQGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAAECNV 753
+S A VV C C GYTGT CE C GY+ + FGG CQPC CN
Sbjct: 131 NSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFG-NPQKFGGSCQPC-------SCNS 182
Query: 754 HGVCIACAHNTTGVHCEQCLPGFYGEPSRGTPG-DCQPC-ACPLTIASN 800
+G +C H TG Q EP +P +C C +C +T+ ++
Sbjct: 183 NGQLGSC-HPLTGDCINQ-------EPKDSSPAEECDDCDSCVMTLLND 223
Score = 54.7 bits (130), Expect = 1e-06
Identities = 28/79 (35%), Positives = 37/79 (46%), Gaps = 13/79 (16%)
Query: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSD--TCDPNTGKC 1419
C C G G C+ CAPGY P+ C PCSCN++ +C P TG C
Sbjct: 146 CSCKAGYTGTQCERCAPGYFGN---------PQKFGGSCQPCSCNSNGQLGSCHPLTGDC 196
Query: 1420 LN--CGDNTAGDHCDVCTS 1436
+N D++ + CD C S
Sbjct: 197 INQEPKDSSPAEECDDCDS 215
Score = 36.2 bits (82), Expect = 0.51
Identities = 26/86 (30%), Positives = 33/86 (38%), Gaps = 19/86 (22%)
Query: 1072 RACDQCSLGY-RDFPD-----CVPCDCDLRGTSGDACNLEQGLCGCVEETGACP-CKENV 1124
R CS GY RD CVPC+C+ G S C + +G C C+ N
Sbjct: 54 RPSQGCSPGYYRDHKGLYTGRCVPCNCN--GHSNQ----------CQDGSGICVNCQHNT 101
Query: 1125 FGPQCNECREGTFALRADNPLGCSPC 1150
G C C+EG + PC
Sbjct: 102 AGEHCERCQEGYYGNAVHGSCRACPC 127
>gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens]
Length = 1111
Score = 358 bits (919), Expect = 5e-98
Identities = 235/647 (36%), Positives = 325/647 (50%), Gaps = 96/647 (14%)
Query: 325 EACNCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPH 384
E C+C+ K++ C +D + +Q T FR C+NC NT GI+CE C +G+YR H
Sbjct: 26 EVCDCNGKSRQCIFDRELHRQ-----TGNGFR----CLNCNDNTDGIHCEKCKNGFYR-H 75
Query: 385 KVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLG 444
+ E + C PCNC+ GSLS+ C G+C CK G TG +CDRC G
Sbjct: 76 R----ERDRCLPCNCNSKGSLSARC------------DNSGRCSCKPGVTGARCDRCLPG 119
Query: 445 Y---------KDYPTCVS-CGCNPVGSASDEPC-TGPCVCKENVEGKACDRCKPGFYNLK 493
+ +D S C C+P G A PC G CVCK V G+ CDRC+ G+YNL
Sbjct: 120 FHMLTDAGCTQDQRLLDSKCDCDPAGIAG--PCDAGRCVCKPAVTGERCDRCRSGYYNLD 177
Query: 494 EKNPRGCSECFCFGVSDVC-SSLSWPVGQVNS-----MSGWLVTDLI-SPRKIPSQQDAL 546
NP GC++CFC+G S C SS + V ++ S + GW SP K+ Q
Sbjct: 178 GGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAVQRNGSPAKLQWSQ--- 234
Query: 547 GGRHQVSINNTAVMQRLAPKYYWAAPEAYLGNKLTAFGGFLKYTVSYDIPVETVDSNLMS 606
RHQ ++ QRL P Y+ AP +LGN+ ++G ++S+D V+ + +
Sbjct: 235 --RHQDVFSSA---QRLDPVYF-VAPAKFLGNQQVSYG----QSLSFDYRVDRGGRHPSA 284
Query: 607 HADVIIKGNGLTLSTQAEGLSLQPYEEYL--NVVRLVPENFQDFHSKR---QIDRDQLMT 661
H DVI++G GL ++ L P + L + + + S Q+ +
Sbjct: 285 H-DVILEGAGLRITAP-----LMPLGKTLPCGLTKTYTFRLNEHPSNNWSPQLSYFEYRR 338
Query: 662 VLANVTHLLIRANYNSAKMALYRLESVSLDIASSNAIDLVVAADVEHCECPQGYTGTSCE 721
+L N+T L IRA Y +++V+L S+ + A VE C CP GY G C+
Sbjct: 339 LLRNLTALRIRATYGEYSTGY--IDNVTL--ISARPVSGAPAPWVEQCICPVGYKGQFCQ 394
Query: 722 SCLSGYYRVDGILFG--GICQPCECHGHAAECNVHGVCIACAHNTTGVHCEQCLPGFYGE 779
C SGY R D G G C PC C G A G C + N + C C GFY +
Sbjct: 395 DCASGYKR-DSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPD-IECADCPIGFYND 452
Query: 780 PSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNP 839
P P C+PC C N FS + + + +EVVC+ C PG +GA CE CADGY+G+P
Sbjct: 453 PH--DPRSCKPCPC-----HNGFSCSV-MPETEEVVCNNCPPGVTGARCELCADGYFGDP 504
Query: 840 TV---PGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCADGFYGDAVT- 895
P C PC C+ NVDPS +G+CD +TG CLKC+ NT G +C++C G++GD +
Sbjct: 505 FGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAP 564
Query: 896 --AKNCRACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYY 940
A CRAC C+ GS C + G C CKP G C+ HG +
Sbjct: 565 NPADKCRACNCNPMGSEPVGCRSD-GTCVCKPGFGGPNCE---HGAF 607
Score = 230 bits (587), Expect = 1e-59
Identities = 262/1165 (22%), Positives = 448/1165 (38%), Gaps = 160/1165 (13%)
Query: 998 CDCPHTQNTC------DPETGE---CV-CPPHTQGVKCEECEDGHWGYDAEVGCQACNCS 1047
CDC C +TG C+ C +T G+ CE+C++G + + C CNC+
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCN 87
Query: 1048 LVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGYRDFPDC----------VPCDCDLRGT 1097
GS RCD +G C CK G CD+C G+ D CDCD G
Sbjct: 88 SKGSLSARCDN-SGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGI 146
Query: 1098 SGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFALRADNPLGCSPCFCSGLSH 1157
+G + G C CK V G +C+ CR G + L NP GC+ CFC G S
Sbjct: 147 AGPC------------DAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSA 194
Query: 1158 LCSELEDYVRTPVTLGSDQPLLRVVSQSNLRGTTEGVYYQAPDFLLDAATVRQHIRAEPF 1217
C +Y +T Q + + + + Q + +A R +P
Sbjct: 195 SCRSSAEYSVHKITSTFHQDVDGWKAVQRNGSPAKLQWSQRHQDVFSSAQ-----RLDPV 249
Query: 1218 YWRLPQQFQGDQLMAYGGKLKYSVAFYSLDGVGTSNFEPQVLIKGG--RIRKQVIYMDAP 1275
Y+ P +F G+Q ++YG L + Y +D G V+++G RI ++ +
Sbjct: 250 YFVAPAKFLGNQQVSYGQSLSFD---YRVDRGGRHPSAHDVILEGAGLRITAPLMPLGKT 306
Query: 1276 APENGVRQEQEVAMRE---NFWKYFNSVSEKPVTREDFMSVLSDIEYILIKASYGQGLQQ 1332
P G+ + + E N W ++ ++ +L ++ + I+A+YG+
Sbjct: 307 LP-CGLTKTYTFRLNEHPSNNW-------SPQLSYFEYRRLLRNLTALRIRATYGE-YST 357
Query: 1333 SRISDISMEVGRKAEKLHPEEEVASLLENCVCPPGTVGFSCQDCAPGYHRGKLPAGSDRG 1392
I ++++ R A +E C+CP G G CQDCA GY R G
Sbjct: 358 GYIDNVTLISARPV-----SGAPAPWVEQCICPVGYKGQFCQDCASGYKRDSARLGP--- 409
Query: 1393 PRPLVAPCVPCSCNNHSDTCDPNTGKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALC 1452
C+PC+C CDP+TG C + GD C C G+Y S C C
Sbjct: 410 ----FGTCIPCNCQG-GGACDPDTGDCYS-GDENPDIECADCPIGFYNDPHDPRS-CKPC 462
Query: 1453 ACPHSPPASFSPTCVLEGDHDFRCDACLLGYEGKHCERCSSSYYGNP---QTPGGSCQKC 1509
C + S P + C+ C G G CE C+ Y+G+P P CQ C
Sbjct: 463 PCHNGFSCSVMPE-----TEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPC 517
Query: 1510 DCNPH--GSVHGDCDRTSGQCV-CRLGASGLRCDEC------EPRHILMETDCVSCDDEC 1560
CN + S G+CDR +G+C+ C +G+ CD+C +P C +C+
Sbjct: 518 QCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNP 577
Query: 1561 VGVLLNDLDEIGDAVLSLNLTGIIPVPYGILSNLENTTKYLQESLLKENMQKDLGKIK-L 1619
+G G V G P Y Q + + + L +++ L
Sbjct: 578 MGSEPVGCRSDGTCVCKPGFGG----PNCEHGAFSCPACYNQVKIQMDQFMQQLQRMEAL 633
Query: 1620 EGVAEETDNLQKKLTRMLASTQKVNRATERIFKESQDLAIAIERLQMSITEIMEKTTLNQ 1679
A+ D + T + Q+ +A + I +++Q A L + + ++ + Q
Sbjct: 634 ISKAQGGDGVVPD-TELEGRMQQAEQALQDILRDAQISEGASRSLGLQLAKVRSQENSYQ 692
Query: 1680 TLDEDFLLPNSTLQNMQQNGTSLLEIMQIRDFTQLHQNATLELKAAEDLLSQ----IQEN 1735
+ +D + T++ ++ G+ ++RD +L L L +E L ++
Sbjct: 693 SRLDDLKM---TVERVRALGSQYQN--RVRDTHRLITQMQLSLAESEASLGNTNIPASDH 747
Query: 1736 YQKPLEELEVLKEAASHVLSKHNNELKAAEALVREAEAKMQESNHLLLMVNANLREFSDK 1795
Y P + L + A+ + H E L RE E +++ L+ K
Sbjct: 748 YVGP-NGFKSLAQEATRLAESHVESASNMEQLTRETEDYSKQALSLV-----------RK 795
Query: 1796 KLHVQEEQNLTSELIVQGRGLIDAAAAQTDAVQDALEHLEDHQDKLLLWSAKIRHHIDDL 1855
LH E + G G D A Q + + LE + +L + + D
Sbjct: 796 ALH---------EGVGSGSGSPDGAVVQ--GLVEKLEKTKSLAQQLTREATQAEIEADRS 844
Query: 1856 VMHMSQRNAVDLVYRAEDHAAEFQRLADVLYSGLENIRNVSLNATSAAYVHYNIQSLIEE 1915
H R D + Q ++D + +E + + A S + SL+
Sbjct: 845 YQHS---------LRLLDSVSRLQGVSDQSFQ-VEEAKRIKQKADS-------LSSLVTR 887
Query: 1916 SEELARDAHRTVTETSLLSESLVSNGKAAVQRSSRFLKEGN-NLSRKLPGIAL------E 1968
+ + + + ++ L+ NGK+ ++S + L N SR +++ E
Sbjct: 888 HMDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYE 947
Query: 1969 LSELRNKTNRFQENAVEITRQTNESLLILRAIPKGIRDKGAKTKELATSASQSAVSTLRD 2028
+ + F + E++ L I + + D KT++ + +A R
Sbjct: 948 VESILKNLREFDLQVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRA 1007
Query: 2029 VAGLSQELLNTSASLSRVNTTLRETHQLLQDSTMATL--LAGRKVKDVEIQANLLFDRLK 2086
G + E L S+ + + +L + D +A LA K + E++
Sbjct: 1008 KNG-AGEALEISSEIEQEIGSLNLEANVTADGALAMEKGLASLKSEMREVEGE------- 1059
Query: 2087 PLKMLEENLSRNLSEIKLLISQARK 2111
L+ E N+ ++++I++A+K
Sbjct: 1060 -LERKELEFDTNMDAVQMVITEAQK 1083
Score = 114 bits (284), Expect = 2e-24
Identities = 56/162 (34%), Positives = 74/162 (45%), Gaps = 17/162 (10%)
Query: 902 CECHVKGSHSAV---CHLETG----LCDCKPNVTGQQCDQCLHGYYGLDSGHGCRPCNCS 954
C+C+ K H +TG +C N G C++C +G+Y C PCNC+
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCN 87
Query: 955 VAGSVSDGCTDEGQCHCVPGVAGKRCDRCAHGFYAYQDGSCT--------PCDCPHTQNT 1006
GS+S C + G+C C PGV G RCDRC GF+ D CT CDC
Sbjct: 88 SKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIA 147
Query: 1007 CDPETGECVCPPHTQGVKCEECEDGHWGYDA--EVGCQACNC 1046
+ G CVC P G +C+ C G++ D GC C C
Sbjct: 148 GPCDAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
Score = 111 bits (278), Expect = 1e-23
Identities = 92/311 (29%), Positives = 116/311 (37%), Gaps = 51/311 (16%)
Query: 921 CDCKPNVTGQQCDQCLHGYYGLDSGHG----CRPCNCSVAGSVSDGCTDEGQCHCVPGVA 976
C C GQ C C GY + G C PCNC G+ D G C+
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDP---DTGDCYSGDENP 438
Query: 977 GKRCDRCAHGFY--AYQDGSCTPCDCPHTQNTCD--PETGECVC---PPHTQGVKCEECE 1029
C C GFY + SC PC C H +C PET E VC PP G +CE C
Sbjct: 439 DIECADCPIGFYNDPHDPRSCKPCPC-HNGFSCSVMPETEEVVCNNCPPGVTGARCELCA 497
Query: 1030 DGHWGYD-AEVG----CQACNCS--LVGSTHHRCDVVTGHC-QCKSKFGGRACDQCSLGY 1081
DG++G E G CQ C C+ + S CD +TG C +C G CDQC GY
Sbjct: 498 DGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGY 557
Query: 1082 RDFP-------DCVPCDCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNECRE 1134
P C C+C+ G+ C + G C CK GP C
Sbjct: 558 FGDPLAPNPADKCRACNCNPMGSEPVGCRSD----------GTCVCKPGFGGP---NCEH 604
Query: 1135 GTFALRADNPLGCSPCFCSGLSHLCSELEDYVRTPVTLGSDQPLLRVVSQSNLRGTTEGV 1194
G F+ C C+ + ++ R + Q VV + L G +
Sbjct: 605 GAFS--------CPACYNQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTELEGRMQQA 656
Query: 1195 YYQAPDFLLDA 1205
D L DA
Sbjct: 657 EQALQDILRDA 667
Score = 106 bits (265), Expect = 3e-22
Identities = 73/229 (31%), Positives = 100/229 (43%), Gaps = 28/229 (12%)
Query: 869 ECLKCLGNTDGAHCERCADGFYGDAVTAK---NCRACECHVKGSHSAVCHLETGLCDCKP 925
+C+ C G C+ CA G+ D+ C C C G+ C +TG C
Sbjct: 381 QCI-CPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSGD 435
Query: 926 NVTGQQCDQCLHGYYG-LDSGHGCRPCNCSVAGSVSDGC-TDEGQCH-CVPGVAGKRCDR 982
+C C G+Y C+PC C S S T+E C+ C PGV G RC+
Sbjct: 436 ENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCEL 495
Query: 983 CAHGFYAYQDGS------CTPCDC-----PHTQNTCDPETGECV-CPPHTQGVKCEECED 1030
CA G++ G C PC C P CD TG C+ C +T G+ C++C+
Sbjct: 496 CADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKA 555
Query: 1031 GHWGYDAEVG----CQACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACD 1075
G++G C+ACNC+ +GS C G C CK FGG C+
Sbjct: 556 GYFGDPLAPNPADKCRACNCNPMGSEPVGCR-SDGTCVCKPGFGGPNCE 603
Score = 79.3 bits (194), Expect = 5e-14
Identities = 52/182 (28%), Positives = 70/182 (38%), Gaps = 31/182 (17%)
Query: 270 CICYGHASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNC 329
C C+ S ET + + C G C C GY P+ G C+ C C
Sbjct: 462 CPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPF--GEHGPVRPCQPCQC 519
Query: 330 HNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPY 389
+N D S + L G C+ C+ NT GI C+ C GY+ ++P
Sbjct: 520 NNNV-----DPSASGNCDRLT--------GRCLKCIHNTAGIYCDQCKAGYF-GDPLAPN 565
Query: 390 EDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYP 449
+ CR CNC+P+GS C D G C CK G+ G C+ G P
Sbjct: 566 PADKCRACNCNPMGSEPVGCRSD------------GTCVCKPGFGGPNCEH---GAFSCP 610
Query: 450 TC 451
C
Sbjct: 611 AC 612
Score = 75.5 bits (184), Expect = 8e-13
Identities = 71/251 (28%), Positives = 84/251 (33%), Gaps = 71/251 (28%)
Query: 280 PWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHN-------- 331
PW E QC C G+ C C GY + R G TC CNC
Sbjct: 377 PWVE-----QCICPVGYKGQFCQDCASGYKRDSARLGPF---GTCIPCNCQGGGACDPDT 428
Query: 332 ------------KAKDC----YYDESVAKQKKSLNTAGQFRGG-------GVCINCLQNT 368
+ DC Y D + K F VC NC
Sbjct: 429 GDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGV 488
Query: 369 MGINCETCIDGYYRPHKVSPYEDEPCRPCNC----DPVGSLSSVCIKDDLHSDLHNGKQP 424
G CE C DGY+ PC+PC C DP S S C +
Sbjct: 489 TGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDP--SASGNC-----------DRLT 535
Query: 425 GQC-PCKEGYTGEKCDRCQLGYKDYP-------TCVSCGCNPVGSASDEP----CTGPCV 472
G+C C G CD+C+ GY P C +C CNP+GS EP G CV
Sbjct: 536 GRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGS---EPVGCRSDGTCV 592
Query: 473 CKENVEGKACD 483
CK G C+
Sbjct: 593 CKPGFGGPNCE 603
Score = 38.9 bits (89), Expect = 0.079
Identities = 29/113 (25%), Positives = 40/113 (35%), Gaps = 26/113 (23%)
Query: 289 QCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKS 348
+C C+ G C+RC PG+H +G C D+ + K
Sbjct: 101 RCSCKPGVTGARCDRCLPGFHM------LTDAG--------------CTQDQRLLDSKCD 140
Query: 349 LNTAGQFR--GGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNC 399
+ AG G C+ C G C+ C GYY +P E C C C
Sbjct: 141 CDPAGIAGPCDAGRCV-CKPAVTGERCDRCRSGYYNLDGGNP---EGCTQCFC 189
>gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens]
Length = 1193
Score = 358 bits (919), Expect = 5e-98
Identities = 235/647 (36%), Positives = 325/647 (50%), Gaps = 96/647 (14%)
Query: 325 EACNCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPH 384
E C+C+ K++ C +D + +Q T FR C+NC NT GI+CE C +G+YR H
Sbjct: 26 EVCDCNGKSRQCIFDRELHRQ-----TGNGFR----CLNCNDNTDGIHCEKCKNGFYR-H 75
Query: 385 KVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLG 444
+ E + C PCNC+ GSLS+ C G+C CK G TG +CDRC G
Sbjct: 76 R----ERDRCLPCNCNSKGSLSARC------------DNSGRCSCKPGVTGARCDRCLPG 119
Query: 445 Y---------KDYPTCVS-CGCNPVGSASDEPC-TGPCVCKENVEGKACDRCKPGFYNLK 493
+ +D S C C+P G A PC G CVCK V G+ CDRC+ G+YNL
Sbjct: 120 FHMLTDAGCTQDQRLLDSKCDCDPAGIAG--PCDAGRCVCKPAVTGERCDRCRSGYYNLD 177
Query: 494 EKNPRGCSECFCFGVSDVC-SSLSWPVGQVNS-----MSGWLVTDLI-SPRKIPSQQDAL 546
NP GC++CFC+G S C SS + V ++ S + GW SP K+ Q
Sbjct: 178 GGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAVQRNGSPAKLQWSQ--- 234
Query: 547 GGRHQVSINNTAVMQRLAPKYYWAAPEAYLGNKLTAFGGFLKYTVSYDIPVETVDSNLMS 606
RHQ ++ QRL P Y+ AP +LGN+ ++G ++S+D V+ + +
Sbjct: 235 --RHQDVFSSA---QRLDPVYF-VAPAKFLGNQQVSYG----QSLSFDYRVDRGGRHPSA 284
Query: 607 HADVIIKGNGLTLSTQAEGLSLQPYEEYL--NVVRLVPENFQDFHSKR---QIDRDQLMT 661
H DVI++G GL ++ L P + L + + + S Q+ +
Sbjct: 285 H-DVILEGAGLRITAP-----LMPLGKTLPCGLTKTYTFRLNEHPSNNWSPQLSYFEYRR 338
Query: 662 VLANVTHLLIRANYNSAKMALYRLESVSLDIASSNAIDLVVAADVEHCECPQGYTGTSCE 721
+L N+T L IRA Y +++V+L S+ + A VE C CP GY G C+
Sbjct: 339 LLRNLTALRIRATYGEYSTGY--IDNVTL--ISARPVSGAPAPWVEQCICPVGYKGQFCQ 394
Query: 722 SCLSGYYRVDGILFG--GICQPCECHGHAAECNVHGVCIACAHNTTGVHCEQCLPGFYGE 779
C SGY R D G G C PC C G A G C + N + C C GFY +
Sbjct: 395 DCASGYKR-DSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPD-IECADCPIGFYND 452
Query: 780 PSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNP 839
P P C+PC C N FS + + + +EVVC+ C PG +GA CE CADGY+G+P
Sbjct: 453 PH--DPRSCKPCPC-----HNGFSCSV-MPETEEVVCNNCPPGVTGARCELCADGYFGDP 504
Query: 840 TV---PGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCADGFYGDAVT- 895
P C PC C+ NVDPS +G+CD +TG CLKC+ NT G +C++C G++GD +
Sbjct: 505 FGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAP 564
Query: 896 --AKNCRACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYY 940
A CRAC C+ GS C + G C CKP G C+ HG +
Sbjct: 565 NPADKCRACNCNPMGSEPVGCRSD-GTCVCKPGFGGPNCE---HGAF 607
Score = 230 bits (587), Expect = 1e-59
Identities = 262/1165 (22%), Positives = 448/1165 (38%), Gaps = 160/1165 (13%)
Query: 998 CDCPHTQNTC------DPETGE---CV-CPPHTQGVKCEECEDGHWGYDAEVGCQACNCS 1047
CDC C +TG C+ C +T G+ CE+C++G + + C CNC+
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCN 87
Query: 1048 LVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGYRDFPDC----------VPCDCDLRGT 1097
GS RCD +G C CK G CD+C G+ D CDCD G
Sbjct: 88 SKGSLSARCDN-SGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGI 146
Query: 1098 SGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFALRADNPLGCSPCFCSGLSH 1157
+G + G C CK V G +C+ CR G + L NP GC+ CFC G S
Sbjct: 147 AGPC------------DAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSA 194
Query: 1158 LCSELEDYVRTPVTLGSDQPLLRVVSQSNLRGTTEGVYYQAPDFLLDAATVRQHIRAEPF 1217
C +Y +T Q + + + + Q + +A R +P
Sbjct: 195 SCRSSAEYSVHKITSTFHQDVDGWKAVQRNGSPAKLQWSQRHQDVFSSAQ-----RLDPV 249
Query: 1218 YWRLPQQFQGDQLMAYGGKLKYSVAFYSLDGVGTSNFEPQVLIKGG--RIRKQVIYMDAP 1275
Y+ P +F G+Q ++YG L + Y +D G V+++G RI ++ +
Sbjct: 250 YFVAPAKFLGNQQVSYGQSLSFD---YRVDRGGRHPSAHDVILEGAGLRITAPLMPLGKT 306
Query: 1276 APENGVRQEQEVAMRE---NFWKYFNSVSEKPVTREDFMSVLSDIEYILIKASYGQGLQQ 1332
P G+ + + E N W ++ ++ +L ++ + I+A+YG+
Sbjct: 307 LP-CGLTKTYTFRLNEHPSNNW-------SPQLSYFEYRRLLRNLTALRIRATYGE-YST 357
Query: 1333 SRISDISMEVGRKAEKLHPEEEVASLLENCVCPPGTVGFSCQDCAPGYHRGKLPAGSDRG 1392
I ++++ R A +E C+CP G G CQDCA GY R G
Sbjct: 358 GYIDNVTLISARPV-----SGAPAPWVEQCICPVGYKGQFCQDCASGYKRDSARLGP--- 409
Query: 1393 PRPLVAPCVPCSCNNHSDTCDPNTGKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALC 1452
C+PC+C CDP+TG C + GD C C G+Y S C C
Sbjct: 410 ----FGTCIPCNCQG-GGACDPDTGDCYS-GDENPDIECADCPIGFYNDPHDPRS-CKPC 462
Query: 1453 ACPHSPPASFSPTCVLEGDHDFRCDACLLGYEGKHCERCSSSYYGNP---QTPGGSCQKC 1509
C + S P + C+ C G G CE C+ Y+G+P P CQ C
Sbjct: 463 PCHNGFSCSVMPE-----TEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPC 517
Query: 1510 DCNPH--GSVHGDCDRTSGQCV-CRLGASGLRCDEC------EPRHILMETDCVSCDDEC 1560
CN + S G+CDR +G+C+ C +G+ CD+C +P C +C+
Sbjct: 518 QCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNP 577
Query: 1561 VGVLLNDLDEIGDAVLSLNLTGIIPVPYGILSNLENTTKYLQESLLKENMQKDLGKIK-L 1619
+G G V G P Y Q + + + L +++ L
Sbjct: 578 MGSEPVGCRSDGTCVCKPGFGG----PNCEHGAFSCPACYNQVKIQMDQFMQQLQRMEAL 633
Query: 1620 EGVAEETDNLQKKLTRMLASTQKVNRATERIFKESQDLAIAIERLQMSITEIMEKTTLNQ 1679
A+ D + T + Q+ +A + I +++Q A L + + ++ + Q
Sbjct: 634 ISKAQGGDGVVPD-TELEGRMQQAEQALQDILRDAQISEGASRSLGLQLAKVRSQENSYQ 692
Query: 1680 TLDEDFLLPNSTLQNMQQNGTSLLEIMQIRDFTQLHQNATLELKAAEDLLSQ----IQEN 1735
+ +D + T++ ++ G+ ++RD +L L L +E L ++
Sbjct: 693 SRLDDLKM---TVERVRALGSQYQN--RVRDTHRLITQMQLSLAESEASLGNTNIPASDH 747
Query: 1736 YQKPLEELEVLKEAASHVLSKHNNELKAAEALVREAEAKMQESNHLLLMVNANLREFSDK 1795
Y P + L + A+ + H E L RE E +++ L+ K
Sbjct: 748 YVGP-NGFKSLAQEATRLAESHVESASNMEQLTRETEDYSKQALSLV-----------RK 795
Query: 1796 KLHVQEEQNLTSELIVQGRGLIDAAAAQTDAVQDALEHLEDHQDKLLLWSAKIRHHIDDL 1855
LH E + G G D A Q + + LE + +L + + D
Sbjct: 796 ALH---------EGVGSGSGSPDGAVVQ--GLVEKLEKTKSLAQQLTREATQAEIEADRS 844
Query: 1856 VMHMSQRNAVDLVYRAEDHAAEFQRLADVLYSGLENIRNVSLNATSAAYVHYNIQSLIEE 1915
H R D + Q ++D + +E + + A S + SL+
Sbjct: 845 YQHS---------LRLLDSVSRLQGVSDQSFQ-VEEAKRIKQKADS-------LSSLVTR 887
Query: 1916 SEELARDAHRTVTETSLLSESLVSNGKAAVQRSSRFLKEGN-NLSRKLPGIAL------E 1968
+ + + + ++ L+ NGK+ ++S + L N SR +++ E
Sbjct: 888 HMDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYE 947
Query: 1969 LSELRNKTNRFQENAVEITRQTNESLLILRAIPKGIRDKGAKTKELATSASQSAVSTLRD 2028
+ + F + E++ L I + + D KT++ + +A R
Sbjct: 948 VESILKNLREFDLQVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRA 1007
Query: 2029 VAGLSQELLNTSASLSRVNTTLRETHQLLQDSTMATL--LAGRKVKDVEIQANLLFDRLK 2086
G + E L S+ + + +L + D +A LA K + E++
Sbjct: 1008 KNG-AGEALEISSEIEQEIGSLNLEANVTADGALAMEKGLASLKSEMREVEGE------- 1059
Query: 2087 PLKMLEENLSRNLSEIKLLISQARK 2111
L+ E N+ ++++I++A+K
Sbjct: 1060 -LERKELEFDTNMDAVQMVITEAQK 1083
Score = 114 bits (284), Expect = 2e-24
Identities = 56/162 (34%), Positives = 74/162 (45%), Gaps = 17/162 (10%)
Query: 902 CECHVKGSHSAV---CHLETG----LCDCKPNVTGQQCDQCLHGYYGLDSGHGCRPCNCS 954
C+C+ K H +TG +C N G C++C +G+Y C PCNC+
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCN 87
Query: 955 VAGSVSDGCTDEGQCHCVPGVAGKRCDRCAHGFYAYQDGSCT--------PCDCPHTQNT 1006
GS+S C + G+C C PGV G RCDRC GF+ D CT CDC
Sbjct: 88 SKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIA 147
Query: 1007 CDPETGECVCPPHTQGVKCEECEDGHWGYDA--EVGCQACNC 1046
+ G CVC P G +C+ C G++ D GC C C
Sbjct: 148 GPCDAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
Score = 111 bits (278), Expect = 1e-23
Identities = 92/311 (29%), Positives = 116/311 (37%), Gaps = 51/311 (16%)
Query: 921 CDCKPNVTGQQCDQCLHGYYGLDSGHG----CRPCNCSVAGSVSDGCTDEGQCHCVPGVA 976
C C GQ C C GY + G C PCNC G+ D G C+
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDP---DTGDCYSGDENP 438
Query: 977 GKRCDRCAHGFY--AYQDGSCTPCDCPHTQNTCD--PETGECVC---PPHTQGVKCEECE 1029
C C GFY + SC PC C H +C PET E VC PP G +CE C
Sbjct: 439 DIECADCPIGFYNDPHDPRSCKPCPC-HNGFSCSVMPETEEVVCNNCPPGVTGARCELCA 497
Query: 1030 DGHWGYD-AEVG----CQACNCS--LVGSTHHRCDVVTGHC-QCKSKFGGRACDQCSLGY 1081
DG++G E G CQ C C+ + S CD +TG C +C G CDQC GY
Sbjct: 498 DGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGY 557
Query: 1082 RDFP-------DCVPCDCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNECRE 1134
P C C+C+ G+ C + G C CK GP C
Sbjct: 558 FGDPLAPNPADKCRACNCNPMGSEPVGCRSD----------GTCVCKPGFGGP---NCEH 604
Query: 1135 GTFALRADNPLGCSPCFCSGLSHLCSELEDYVRTPVTLGSDQPLLRVVSQSNLRGTTEGV 1194
G F+ C C+ + ++ R + Q VV + L G +
Sbjct: 605 GAFS--------CPACYNQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTELEGRMQQA 656
Query: 1195 YYQAPDFLLDA 1205
D L DA
Sbjct: 657 EQALQDILRDA 667
Score = 106 bits (265), Expect = 3e-22
Identities = 73/229 (31%), Positives = 100/229 (43%), Gaps = 28/229 (12%)
Query: 869 ECLKCLGNTDGAHCERCADGFYGDAVTAK---NCRACECHVKGSHSAVCHLETGLCDCKP 925
+C+ C G C+ CA G+ D+ C C C G+ C +TG C
Sbjct: 381 QCI-CPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSGD 435
Query: 926 NVTGQQCDQCLHGYYG-LDSGHGCRPCNCSVAGSVSDGC-TDEGQCH-CVPGVAGKRCDR 982
+C C G+Y C+PC C S S T+E C+ C PGV G RC+
Sbjct: 436 ENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCEL 495
Query: 983 CAHGFYAYQDGS------CTPCDC-----PHTQNTCDPETGECV-CPPHTQGVKCEECED 1030
CA G++ G C PC C P CD TG C+ C +T G+ C++C+
Sbjct: 496 CADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKA 555
Query: 1031 GHWGYDAEVG----CQACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACD 1075
G++G C+ACNC+ +GS C G C CK FGG C+
Sbjct: 556 GYFGDPLAPNPADKCRACNCNPMGSEPVGCR-SDGTCVCKPGFGGPNCE 603
Score = 79.3 bits (194), Expect = 5e-14
Identities = 52/182 (28%), Positives = 70/182 (38%), Gaps = 31/182 (17%)
Query: 270 CICYGHASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNC 329
C C+ S ET + + C G C C GY P+ G C+ C C
Sbjct: 462 CPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPF--GEHGPVRPCQPCQC 519
Query: 330 HNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPY 389
+N D S + L G C+ C+ NT GI C+ C GY+ ++P
Sbjct: 520 NNNV-----DPSASGNCDRLT--------GRCLKCIHNTAGIYCDQCKAGYF-GDPLAPN 565
Query: 390 EDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYP 449
+ CR CNC+P+GS C D G C CK G+ G C+ G P
Sbjct: 566 PADKCRACNCNPMGSEPVGCRSD------------GTCVCKPGFGGPNCEH---GAFSCP 610
Query: 450 TC 451
C
Sbjct: 611 AC 612
Score = 75.5 bits (184), Expect = 8e-13
Identities = 71/251 (28%), Positives = 84/251 (33%), Gaps = 71/251 (28%)
Query: 280 PWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHN-------- 331
PW E QC C G+ C C GY + R G TC CNC
Sbjct: 377 PWVE-----QCICPVGYKGQFCQDCASGYKRDSARLGPF---GTCIPCNCQGGGACDPDT 428
Query: 332 ------------KAKDC----YYDESVAKQKKSLNTAGQFRGG-------GVCINCLQNT 368
+ DC Y D + K F VC NC
Sbjct: 429 GDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGV 488
Query: 369 MGINCETCIDGYYRPHKVSPYEDEPCRPCNC----DPVGSLSSVCIKDDLHSDLHNGKQP 424
G CE C DGY+ PC+PC C DP S S C +
Sbjct: 489 TGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDP--SASGNC-----------DRLT 535
Query: 425 GQC-PCKEGYTGEKCDRCQLGYKDYP-------TCVSCGCNPVGSASDEP----CTGPCV 472
G+C C G CD+C+ GY P C +C CNP+GS EP G CV
Sbjct: 536 GRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGS---EPVGCRSDGTCV 592
Query: 473 CKENVEGKACD 483
CK G C+
Sbjct: 593 CKPGFGGPNCE 603
Score = 38.9 bits (89), Expect = 0.079
Identities = 29/113 (25%), Positives = 40/113 (35%), Gaps = 26/113 (23%)
Query: 289 QCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKS 348
+C C+ G C+RC PG+H +G C D+ + K
Sbjct: 101 RCSCKPGVTGARCDRCLPGFHM------LTDAG--------------CTQDQRLLDSKCD 140
Query: 349 LNTAGQFR--GGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNC 399
+ AG G C+ C G C+ C GYY +P E C C C
Sbjct: 141 CDPAGIAGPCDAGRCV-CKPAVTGERCDRCRSGYYNLDGGNP---EGCTQCFC 189
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 353 bits (905), Expect = 2e-96
Identities = 207/570 (36%), Positives = 280/570 (49%), Gaps = 43/570 (7%)
Query: 961 DGCTDEGQCHCVPGVAGKRCDRCAHGFYAYQDG----SCTPCDCPHTQNTCDPETGECV- 1015
D + QC C PG G C C G+ G +C C C C+PETG C
Sbjct: 1118 DPALEVEQCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACEPETGACQG 1177
Query: 1016 CPPHTQGVKCEECEDGHWGYDAEVG----CQACNC---SLVGSTHHRCDVVT-GH--CQ- 1064
C HT+G +CE+C+ G++G DA+ G CQ C C G H C + T GH C
Sbjct: 1178 CQHHTEGPRCEQCQPGYYG-DAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDA 1236
Query: 1065 CKSKFGGRACDQCSLGYRDFPDC-VPC--DCDLRGTSGDACNLEQGLCGCVEETGACPCK 1121
C GR C++C+ GY P PC D + G G C+ + + + G C CK
Sbjct: 1237 CSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDAAGQCQCK 1296
Query: 1122 ENVFGPQCNECREGTFALRADNPLGCSPCFCSGLSHLCSE---LEDYVRTPVTLGSDQPL 1178
V G C+ CR F L A NP GC PCFC G++ C+ + T G Q
Sbjct: 1297 AQVEGLTCSHCRPHHFHLSASNPDGCLPCFCMGITQQCASSAYTRHLISTHFAPGDFQGF 1356
Query: 1179 LRVVSQSNLRGTTEGVYYQAPDFLLDAATVRQHIRAEPFYWRLPQQFQGDQLMAYGGKLK 1238
V Q N R T E P+ + + E FYW+LP+ +QGD++ AYGGKL+
Sbjct: 1357 ALVNPQRNSRLTGEFTVEPVPEGAQLSFGNFAQLGHESFYWQLPETYQGDKVAAYGGKLR 1416
Query: 1239 YSVAFYSLDGVGTSNFEPQVLIKGGRIRKQVIYMDAPAPENGVRQEQEVAMRENFWKYFN 1298
Y+++ Y+ G+ +P V I G I ++ PA + R+ E+ RE FW+ +
Sbjct: 1417 YTLS-YTAGPQGSPLSDPDVQITGNNI---MLVASQPALQGPERRSYEIMFREEFWRRPD 1472
Query: 1299 SVSEKPVTREDFMSVLSDIEYILIKASYGQGLQQSRISDISMEVGRKAEKLHPEEEVASL 1358
+P TRE + L+D++ +LI+A++ + IS +S+EV + P A
Sbjct: 1473 G---QPATREHLLMALADLDELLIRATFSSVPLAASISAVSLEVAQPGPSNRPR---ALE 1526
Query: 1359 LENCVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGK 1418
+E C CPPG +G SCQDCAPGY R G + C C CN HSD C P TG
Sbjct: 1527 VEECRCPPGYIGLSCQDCAPGYTR--------TGSGLYLGHCELCECNGHSDLCHPETGA 1578
Query: 1419 CLNCGDNTAGDHCDVCTSGYYGKVT-GSASDCALCACPHSPPAS-FSPTCVLEGDHDFRC 1476
C C N AG+ C++C GYYG T G+ DC CACP + P + FS TC G +RC
Sbjct: 1579 CSQCQHNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRC 1638
Query: 1477 DACLLGYEGKHCERCSSSYYGNPQTPGGSC 1506
AC GY G++CE+C Y GNP GG C
Sbjct: 1639 TACEPGYTGQYCEQCGPGYVGNPSVQGGQC 1668
Score = 347 bits (891), Expect = 8e-95
Identities = 215/638 (33%), Positives = 311/638 (48%), Gaps = 79/638 (12%)
Query: 968 QCHCVPGVAGKRCDRCAHGFYAYQDG----SCTPCDCPHTQNTCDPETGECV-CPPHTQG 1022
+C C G +G C+ C F G +C+ C+C ++CDP G C+ C +T+G
Sbjct: 730 ECRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCNCNGHASSCDPVYGHCLNCQHNTEG 789
Query: 1023 VKCEECEDGHWGYDA----EVGCQACNCSLVGSTHHRCDV----VTGHCQCKS---KFGG 1071
+C +C+ G +G DA C+ C C + ++ D G C + + G
Sbjct: 790 PQCNKCKAGFFG-DAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGYTG 848
Query: 1072 RACDQCSLGYRDFP-----DCVPCD-----CDLRGTSGDACNLEQGLCGCVEETGACPCK 1121
R C+ C+ GY P C P + CD RG+ G + AC CK
Sbjct: 849 RRCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMGTSGE-------------ACRCK 895
Query: 1122 ENVFGPQCNECREGTFALRADNPLGCSPCFCSGLSHLCSELEDYVRTPVTLGSDQP-LLR 1180
NV G CNEC +G+F L NP GC CFC G+S C+ + R + S++P
Sbjct: 896 NNVVGRLCNECADGSFHLSTRNPDGCLKCFCMGVSRHCTS-SSWSRAQLHGASEEPGHFS 954
Query: 1181 VVSQSNLRGTTEGVYYQAPDFLLDAATVRQHIRAEPFYWRLPQQFQGDQLMAYGGKLKYS 1240
+ + ++ T EG++ P L ++ R + + P++W LP +F GD++ +YGG+L+++
Sbjct: 955 LTNAASTHTTNEGIFSPTPGELGFSSFHR--LLSGPYFWSLPSRFLGDKVTSYGGELRFT 1012
Query: 1241 VAFYSLDGVGTSNFEPQVLIKGGRIRKQVIYMDAPAPENGVRQEQEVAMRENFWKYFNSV 1300
V S G + +P V+++G I + P+P G V RE W+
Sbjct: 1013 VTQRSQPGSTPLHGQPLVVLQGNNIILEHHVAQEPSP--GQPSTFIVPFREQAWQ---RP 1067
Query: 1301 SEKPVTREDFMSVLSDIEYILIKASYGQGLQQSRISDISMEVGRKAEKLHPEEEVASLLE 1360
+P TRE + L+ I+ +LI+ASY Q +SR+S ISM+V E ++ A +E
Sbjct: 1068 DGQPATREHLLMALAGIDTLLIRASYAQQPAESRVSGISMDVAVPEE---TGQDPALEVE 1124
Query: 1361 NCVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKCL 1420
C CPPG G SCQDC GY R P+G G C CSC+ HS+ C+P TG C
Sbjct: 1125 QCSCPPGYRGPSCQDCDTGYTR--TPSGLYLG------TCERCSCHGHSEACEPETGACQ 1176
Query: 1421 NCGDNTAGDHCDVCTSGYYGKV-TGSASDCALCACPHSPPA-SFSPTCVLEGDHDFRCDA 1478
C +T G C+ C GYYG G+ DC LC C P A + TC L+ D CDA
Sbjct: 1177 GCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDA 1236
Query: 1479 CLLGYEGKHCERCSSSYYGNPQTPGGSCQK---------CDCNPHGSVHGDCDRTSGQCV 1529
C G+ G+HCERC+ YYGNP + G CQ+ C+C+P GSV CD +GQC
Sbjct: 1237 CSPGHSGRHCERCAPGYYGNP-SQGQPCQRDSQVPGPIGCNCDPQGSVSSQCD-AAGQCQ 1294
Query: 1530 CRLGASGLRCDECEPRHILMETD----CVSCDDECVGV 1563
C+ GL C C P H + C+ C C+G+
Sbjct: 1295 CKAQVEGLTCSHCRPHHFHLSASNPDGCLPC--FCMGI 1330
Score = 333 bits (854), Expect = 2e-90
Identities = 201/594 (33%), Positives = 274/594 (46%), Gaps = 82/594 (13%)
Query: 289 QCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSG---NTCEACNCHNKAKDCYYDESVAKQ 345
QC C G SC C GY + P SG TCE C+CH ++ C +
Sbjct: 1125 QCSCPPGYRGPSCQDCDTGYTRTP-------SGLYLGTCERCSCHGHSEACEPET----- 1172
Query: 346 KKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPV-GS 404
G C C +T G CE C GYY + +D PC DP G
Sbjct: 1173 -------------GACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQ 1219
Query: 405 LSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYPT----C--------- 451
+ C D +D H P C G++G C+RC GY P+ C
Sbjct: 1220 AAHTCFLD---TDGH----PTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGP 1272
Query: 452 VSCGCNPVGSASDE-PCTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFCFGVSD 510
+ C C+P GS S + G C CK VEG C C+P ++L NP GC CFC G++
Sbjct: 1273 IGCNCDPQGSVSSQCDAAGQCQCKAQVEGLTCSHCRPHHFHLSASNPDGCLPCFCMGITQ 1332
Query: 511 VCSSLSWPVGQVNS------MSGWLVTDLISPRKIPSQQDALGGRH---------QVSIN 555
C+S ++ +++ G+ + + P + L G Q+S
Sbjct: 1333 QCASSAYTRHLISTHFAPGDFQGFALVN-------PQRNSRLTGEFTVEPVPEGAQLSFG 1385
Query: 556 NTAVMQRLAPKYYWAAPEAYLGNKLTAFGGFLKYTVSYDIPVETVDSNLMSHADVIIKGN 615
N A + +YW PE Y G+K+ A+GG L+YT+SY + + +S DV I GN
Sbjct: 1386 NFAQLGH--ESFYWQLPETYQGDKVAAYGGKLRYTLSYTAGPQ---GSPLSDPDVQITGN 1440
Query: 616 GLTLSTQAEGLSLQPYEEYLNVVRLVPENFQDFHSKRQIDRDQLMTVLANVTHLLIRANY 675
+ L L Y + R E F + R+ L+ LA++ LLIRA +
Sbjct: 1441 NIMLVASQPALQGPERRSYEIMFR---EEFWRRPDGQPATREHLLMALADLDELLIRATF 1497
Query: 676 NSAKMALYRLESVSLDIASSNAIDLVVAADVEHCECPQGYTGTSCESCLSGYYRVDGILF 735
+S +A + +VSL++A + A +VE C CP GY G SC+ C GY R L+
Sbjct: 1498 SSVPLAA-SISAVSLEVAQPGPSNRPRALEVEECRCPPGYIGLSCQDCAPGYTRTGSGLY 1556
Query: 736 GGICQPCECHGHAAECNVH-GVCIACAHNTTGVHCEQCLPGFYGEPSRGTPGDCQPCACP 794
G C+ CEC+GH+ C+ G C C HN G CE C PG+YG+ + GTP DCQPCACP
Sbjct: 1557 LGHCELCECNGHSDLCHPETGACSQCQHNAAGEFCELCAPGYYGDATAGTPEDCQPCACP 1616
Query: 795 LTIASNNFSPTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNPTVPGESCVP 848
LT N FS TC C C PGY+G +CE+C GY GNP+V G C+P
Sbjct: 1617 LTNPENMFSRTCESLGAGGYRCTACEPGYTGQYCEQCGPGYVGNPSVQGGQCLP 1670
Score = 319 bits (818), Expect = 2e-86
Identities = 204/640 (31%), Positives = 290/640 (45%), Gaps = 66/640 (10%)
Query: 289 QCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKS 348
+C+C G SC C + + P P TC CNC+ A C + V
Sbjct: 730 ECRCPIGYSGLSCESCDAHFTRVPGGPYL----GTCSGCNCNGHASSC---DPVY----- 777
Query: 349 LNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNC---DPVGSL 405
G C+NC NT G C C G++ + CRPC C D
Sbjct: 778 ----------GHCLNCQHNTEGPQCNKCKAGFFGDAMKATATS--CRPCPCPYIDASRRF 825
Query: 406 SSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYPTCVSCGCNPVGS---- 461
S C D Q C GYTG +C+ C GY+ P C PV
Sbjct: 826 SDTCFLD-------TDGQATCDACAPGYTGRRCESCAPGYEGNPIQPGGKCRPVNQEIVR 878
Query: 462 ----ASDEPCTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFCFGVSDVCSSLSW 517
S C CK NV G+ C+ C G ++L +NP GC +CFC GVS C+S SW
Sbjct: 879 CDERGSMGTSGEACRCKNNVVGRLCNECADGSFHLSTRNPDGCLKCFCMGVSRHCTSSSW 938
Query: 518 PVGQVNSMSG----WLVTDLISPRKIPSQQDALGGRHQVSINNTAVMQRLAPKYYWAAPE 573
Q++ S + +T+ S + + + + ++ + L+ Y+W+ P
Sbjct: 939 SRAQLHGASEEPGHFSLTNAASTH---TTNEGIFSPTPGELGFSSFHRLLSGPYFWSLPS 995
Query: 574 AYLGNKLTAFGGFLKYTVSYDIPVETVDSNLMSHADVIIKGNGLTLSTQAEGLSLQPYEE 633
+LG+K+T++GG L++TV+ + + L V+++GN + L P +
Sbjct: 996 RFLGDKVTSYGGELRFTVTQRS--QPGSTPLHGQPLVVLQGNNIILEHHV-AQEPSPGQP 1052
Query: 634 YLNVVRLVPENFQDFHSKRQIDRDQLMTVLANVTHLLIRANYNSAKMALYRLESVSLDIA 693
+V + +Q + R+ L+ LA + LLIRA+Y + + A R+ +S+D+A
Sbjct: 1053 STFIVPFREQAWQR-PDGQPATREHLLMALAGIDTLLIRASY-AQQPAESRVSGISMDVA 1110
Query: 694 SSNAIDLVVAADVEHCECPQGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAAECNV 753
A +VE C CP GY G SC+ C +GY R L+ G C+ C CHGH+ C
Sbjct: 1111 VPEETGQDPALEVEQCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACEP 1170
Query: 754 H-GVCIACAHNTTGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGD 812
G C C H+T G CEQC PG+YG+ RGTP DCQ C C A+ + TC L+
Sbjct: 1171 ETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDG 1230
Query: 813 EVVCDWCAPGYSGAWCERCADGYYGNPTVPGESC-----VPCDCSGNVDP--SEAGHCDS 865
CD C+PG+SG CERCA GYYGNP+ G+ C VP N DP S + CD+
Sbjct: 1231 HPTCDACSPGHSGRHCERCAPGYYGNPS-QGQPCQRDSQVPGPIGCNCDPQGSVSSQCDA 1289
Query: 866 VTGECLKCLGNTDGAHCERC-ADGFYGDAVTAKNCRACEC 904
G+C +C +G C C F+ A C C C
Sbjct: 1290 -AGQC-QCKAQVEGLTCSHCRPHHFHLSASNPDGCLPCFC 1327
Score = 246 bits (629), Expect = 2e-64
Identities = 149/437 (34%), Positives = 212/437 (48%), Gaps = 32/437 (7%)
Query: 485 CKPGFYNLKEKNPRGCSECFCFGVSDVCSS-------LSWPVGQVNSMSGWLVTDLISPR 537
C G + L+ C CFCFG++ VC S + Q + G VT P
Sbjct: 505 CPDGHFYLEHS--AACLPCFCFGITSVCQSTRRFRDQIRLRFDQPDDFKGVNVTMPAQPG 562
Query: 538 KIPSQQDALG---GRHQVSINNTAVMQRLAPKYYWAAPEAYLGNKLTAFGGFLKYTVSYD 594
P L H+ + + + + L +WA PE +LGNK+ ++GG L+Y V Y+
Sbjct: 563 TPPLSSTQLQIDPSLHEFQLVDLS-RRFLVHDSFWALPEQFLGNKVDSYGGSLRYNVRYE 621
Query: 595 IPVETVDSNLMSHADVIIKGNGLTLSTQAEGLSLQPYEEYLNVVRLVPENFQDFHSKRQI 654
+ ++ + DV++ G G L ++ QP V+ E++ S R +
Sbjct: 622 LARGMLEP--VQRPDVVLMGAGYRLLSRGH-TPTQPGALNQRQVQFSEEHWVH-ESGRPV 677
Query: 655 DRDQLMTVLANVTHLLIRANYNSAKMALYRLESVSLDIASSNAIDLVVAADVEHCECPQG 714
R +L+ VL ++ +LI+ YN+ KMA L +++D ++A A VE C CP G
Sbjct: 678 QRAELLQVLQSLEAVLIQTVYNT-KMASVGLSDIAMDTTVTHATSHGRAHSVEECRCPIG 736
Query: 715 YTGTSCESCLSGYYRVDGILFGGICQPCECHGHAAECN-VHGVCIACAHNTTGVHCEQCL 773
Y+G SCESC + + RV G + G C C C+GHA+ C+ V+G C+ C HNT G C +C
Sbjct: 737 YSGLSCESCDAHFTRVPGGPYLGTCSGCNCNGHASSCDPVYGHCLNCQHNTEGPQCNKCK 796
Query: 774 PGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYSGAWCERCAD 833
GF+G+ + T C+PC CP AS FS TC L+ + CD CAPGY+G CE CA
Sbjct: 797 AGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGYTGRRCESCAP 856
Query: 834 GYYGNPTVPGESCVPCDCSGNVDPSEAGHCD-----SVTGECLKCLGNTDGAHCERCADG 888
GY GNP PG C P + E CD +GE +C N G C CADG
Sbjct: 857 GYEGNPIQPGGKCRPVN-------QEIVRCDERGSMGTSGEACRCKNNVVGRLCNECADG 909
Query: 889 -FYGDAVTAKNCRACEC 904
F+ C C C
Sbjct: 910 SFHLSTRNPDGCLKCFC 926
Score = 213 bits (542), Expect = 2e-54
Identities = 139/458 (30%), Positives = 210/458 (45%), Gaps = 49/458 (10%)
Query: 1127 PQCNECREGTFALRADNPLGCSPCFCSGLSHLCSELEDYVRTPVTLGSDQP--------- 1177
PQ C +G F L ++ C PCFC G++ +C + R + L DQP
Sbjct: 500 PQRGPCPDGHFYL--EHSAACLPCFCFGITSVCQSTRRF-RDQIRLRFDQPDDFKGVNVT 556
Query: 1178 LLRVVSQSNLRGTTEGVYYQAPDFLLDAATVRQHIRAEPFYWRLPQQFQGDQLMAYGGKL 1237
+ L T + +F L + + +W LP+QF G+++ +YGG L
Sbjct: 557 MPAQPGTPPLSSTQLQIDPSLHEFQL--VDLSRRFLVHDSFWALPEQFLGNKVDSYGGSL 614
Query: 1238 KYSVAFYSLDGVGTSNFEPQVLIKGGRIRKQVIYMDAPAPENGVRQEQEVAMRENFWKYF 1297
+Y+V + G+ P V++ G R ++ + G +++V E W +
Sbjct: 615 RYNVRYELARGMLEPVQRPDVVLMGAGYR--LLSRGHTPTQPGALNQRQVQFSEEHWVH- 671
Query: 1298 NSVSEKPVTREDFMSVLSDIEYILIKASYGQGLQQSRISDISMEVGRKAEKLHPEEEVAS 1357
S +PV R + + VL +E +LI+ Y + +SDI+M+ H A
Sbjct: 672 --ESGRPVQRAELLQVLQSLEAVLIQTVYNTKMASVGLSDIAMDTTVTHATSHGR---AH 726
Query: 1358 LLENCVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTG 1417
+E C CP G G SC+ C H ++P G P + C C+CN H+ +CDP G
Sbjct: 727 SVEECRCPIGYSGLSCESCDA--HFTRVPGG------PYLGTCSGCNCNGHASSCDPVYG 778
Query: 1418 KCLNCGDNTAGDHCDVCTSGYYG-KVTGSASDCALCACPH-SPPASFSPTCVLEGDHDFR 1475
CLNC NT G C+ C +G++G + +A+ C C CP+ FS TC L+ D
Sbjct: 779 HCLNCQHNTEGPQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQAT 838
Query: 1476 CDACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCD-----CNPHGSVHGDCDRTSGQ-CV 1529
CDAC GY G+ CE C+ Y GNP PGG C+ + C+ GS+ TSG+ C
Sbjct: 839 CDACAPGYTGRRCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSM-----GTSGEACR 893
Query: 1530 CRLGASGLRCDECEPRHILMET----DCVSCDDECVGV 1563
C+ G C+EC + T C+ C C+GV
Sbjct: 894 CKNNVVGRLCNECADGSFHLSTRNPDGCLKC--FCMGV 929
Score = 127 bits (320), Expect = 1e-28
Identities = 78/212 (36%), Positives = 100/212 (47%), Gaps = 28/212 (13%)
Query: 819 CAPGYSGAWCERCADGYYGNPT-VPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNT 877
C PGY G C+ C GY P+ + +C C C G+ SEA C+ TG C C +T
Sbjct: 1128 CPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGH---SEA--CEPETGACQGCQHHT 1182
Query: 878 DGAHCERCADGFYGDAV--TAKNCRACECH---VKGSHSAVCHLETG---LCD-CKPNVT 928
+G CE+C G+YGDA T ++C+ C C+ G + C L+T CD C P +
Sbjct: 1183 EGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHS 1242
Query: 929 GQQCDQCLHGYYGLDS-GHGCRP---------CNCSVAGSVSDGCTDEGQCHCVPGVAGK 978
G+ C++C GYYG S G C+ CNC GSVS C GQC C V G
Sbjct: 1243 GRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDAAGQCQCKAQVEGL 1302
Query: 979 RCDRC-AHGFY--AYQDGSCTPCDCPHTQNTC 1007
C C H F+ A C PC C C
Sbjct: 1303 TCSHCRPHHFHLSASNPDGCLPCFCMGITQQC 1334
Score = 88.2 bits (217), Expect = 1e-16
Identities = 67/213 (31%), Positives = 82/213 (38%), Gaps = 42/213 (19%)
Query: 916 LETGLCDCKPNVTGQQCDQCLHGYYGLDSG---HGCRPCNCSVAGSVSDGCTDE-GQCH- 970
LE C C P G C C GY SG C C+C S+ C E G C
Sbjct: 1121 LEVEQCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCH---GHSEACEPETGACQG 1177
Query: 971 CVPGVAGKRCDRCAHGFYA-YQDGSCTPCDCPHTQNTCDPETGEC--------------- 1014
C G RC++C G+Y Q G TP DC DP G+
Sbjct: 1178 CQHHTEGPRCEQCQPGYYGDAQRG--TPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCD 1235
Query: 1015 VCPPHTQGVKCEECEDGHWG---------YDAEV-GCQACNCSLVGSTHHRCDVVTGHCQ 1064
C P G CE C G++G D++V G CNC GS +CD G CQ
Sbjct: 1236 ACSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCD-AAGQCQ 1294
Query: 1065 CKSKFGGRACDQC-----SLGYRDFPDCVPCDC 1092
CK++ G C C L + C+PC C
Sbjct: 1295 CKAQVEGLTCSHCRPHHFHLSASNPDGCLPCFC 1327
Score = 87.4 bits (215), Expect = 2e-16
Identities = 56/145 (38%), Positives = 70/145 (48%), Gaps = 19/145 (13%)
Query: 819 CAPGYSGAWCERCADGYY--GNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGN 876
C PGY G C+ CA GY G+ G C C+C+G+ D C TG C +C N
Sbjct: 1532 CPPGYIGLSCQDCAPGYTRTGSGLYLGH-CELCECNGHSDL-----CHPETGACSQCQHN 1585
Query: 877 TDGAHCERCADGFYGDAV--TAKNCRACEC---HVKGSHSAVCH-LETG---LCDCKPNV 927
G CE CA G+YGDA T ++C+ C C + + S C L G C+P
Sbjct: 1586 AAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGY 1645
Query: 928 TGQQCDQCLHGYYGLDSGHG--CRP 950
TGQ C+QC GY G S G C P
Sbjct: 1646 TGQYCEQCGPGYVGNPSVQGGQCLP 1670
Score = 79.3 bits (194), Expect = 5e-14
Identities = 99/443 (22%), Positives = 176/443 (39%), Gaps = 64/443 (14%)
Query: 2496 YIELPP-KSLSPESEWLVTFATTNSSGIIL----AALGGDVEKRGDREEAHVPFFSVMLI 2550
++ LP K + E +TF ++ G++L + G +R+ F S L+
Sbjct: 3673 FLPLPTIKDAYRKFEIKITFRPDSADGMLLYNGQKRVPGSPTNLANRQP---DFISFGLV 3729
Query: 2551 GGNIEVHVNPGDGTGLRKALLHAPTGTCSDGQAHSISLVRNRRIITVQLDENNPVEMKLG 2610
GG E + G G A + PT G H+++L+R+ ++ + + PV
Sbjct: 3730 GGRPEFRFDAGSGM----ATIRHPTPLAL-GHFHTVTLLRSLTQGSLIVGDLAPVNGTSQ 3784
Query: 2611 TLVESRTINVSNLYVGGIPEGEGTSLLTMRRSFHGCIKNLIFNLELLDFN--SAVGHEQV 2668
+ +N LY+GG P+ + F GC++ L E + F+ + H
Sbjct: 3785 GKFQGLDLN-EELYLGGYPDYGAIPKAGLSSGFIGCVRELRIQGEEIVFHDLNLTAHGIS 3843
Query: 2669 DLDTCWLSERP----KLAPDAEDSKLLPE-PRAF--------------PEQCVVDAALEY 2709
TC +RP D+E S + P F PE C DA
Sbjct: 3844 HCPTC--RDRPCQNGGQCHDSESSSYVCVCPAGFTGSRCEHSQALHCHPEACGPDATCVN 3901
Query: 2710 VPGAHQF---------------GLT--------QNSHFILPFNQSAVRKKLSVELSIRTF 2746
P + G+T S+ LP + +L +++ +
Sbjct: 3902 RPDGRGYTCRCHLGRSGLRCEEGVTVTTPSLSGAGSYLALPALTNT-HHELRLDVEFKPL 3960
Query: 2747 ASSGLIYYMAHQNQA--DYAVLQLHGGRLHFMFDLGKGRTKVSHPALLSDGKWHTVKTDY 2804
A G++ + ++ D+ L + GG L F ++LG G + L+ G+WH V +
Sbjct: 3961 APDGVLLFSGGKSGPVEDFVSLAMVGGHLEFRYELGSGLAVLRSAEPLALGRWHRVSAER 4020
Query: 2805 VKRKGFITVDGRESPMVTVVGDGTMLDVEGLFYLGGLPSQYQARKIGNITHSIPACIGDV 2864
+ + G + V+G + + G L++ L YLGG+ N++ C+G+V
Sbjct: 4021 LNKDGSLRVNGGRPVLRSSPGKSQGLNLHTLLYLGGVEPSVPLSPATNMSAHFRGCVGEV 4080
Query: 2865 TVNSKQLDKD-SPVSAFTVNRCY 2886
+VN K+LD S + + + +CY
Sbjct: 4081 SVNGKRLDLTYSFLGSQGIGQCY 4103
Score = 77.4 bits (189), Expect = 2e-13
Identities = 57/178 (32%), Positives = 95/178 (53%), Gaps = 15/178 (8%)
Query: 2132 PQISSTNYNT-LTLNVKTQEPDNLLFYLG--SSTASDFLAVEMRRGRVAFLWDLGSGSTR 2188
P +++T++ L + K PD +L + G S DF+++ M G + F ++LGSG
Sbjct: 3942 PALTNTHHELRLDVEFKPLAPDGVLLFSGGKSGPVEDFVSLAMVGGHLEFRYELGSGLAV 4001
Query: 2189 LEFPDFPIDDNRWHSIHVARFGNIGSLSVKEMSSNQKSPTKTSKSPGTANVLDVNNSTLM 2248
L + P+ RWH + R GSL V N P S SPG + L+++ TL+
Sbjct: 4002 LRSAE-PLALGRWHRVSAERLNKDGSLRV-----NGGRPVLRS-SPGKSQGLNLH--TLL 4052
Query: 2249 FVGGLGGQIKKSPAVKVT-HFKGCLGEAFLNGKSIGL-WNYIEREGKCRGCFGSSQNE 2304
++GG+ + SPA ++ HF+GC+GE +NGK + L ++++ +G C+ SS E
Sbjct: 4053 YLGGVEPSVPLSPATNMSAHFRGCVGEVSVNGKRLDLTYSFLGSQG-IGQCYDSSPCE 4109
Score = 70.1 bits (170), Expect = 3e-11
Identities = 93/423 (21%), Positives = 154/423 (36%), Gaps = 99/423 (23%)
Query: 2716 FGLTQNSHFILPFNQSAVRKKLSVELSIRTFASSGLIYYMAHQN-----------QADYA 2764
F T S LP + A RK ++++ R ++ G++ Y + Q D+
Sbjct: 3666 FTQTPYSFLPLPTIKDAYRK-FEIKITFRPDSADGMLLYNGQKRVPGSPTNLANRQPDFI 3724
Query: 2765 VLQLHGGRLHFMFDLGKGRTKVSHPALLSDGKWHTVKTDYVKRKGFITVDGRESPMVTVV 2824
L GGR F FD G G + HP L+ G +HTV +G + V T
Sbjct: 3725 SFGLVGGRPEFRFDAGSGMATIRHPTPLALGHFHTVTLLRSLTQGSLIVGDLAPVNGTSQ 3784
Query: 2825 GDGTMLDVEGLFYLGGLPSQYQARKIGNITHSIPACIGDVTVNSKQL------------- 2871
G LD+ YLGG P Y A ++ C+ ++ + +++
Sbjct: 3785 GKFQGLDLNEELYLGGYP-DYGAIPKAGLSSGFIGCVRELRIQGEEIVFHDLNLTAHGIS 3843
Query: 2872 ----DKDSPV-------------------SAFTVNRC----------YAVAQEGTYF--- 2895
+D P + FT +RC A + T
Sbjct: 3844 HCPTCRDRPCQNGGQCHDSESSSYVCVCPAGFTGSRCEHSQALHCHPEACGPDATCVNRP 3903
Query: 2896 DGSGYAA---LVKEGYKVQSDVNIT--------------------------LEFRTSSQN 2926
DG GY L + G + + V +T +EF+ + +
Sbjct: 3904 DGRGYTCRCHLGRSGLRCEEGVTVTTPSLSGAGSYLALPALTNTHHELRLDVEFKPLAPD 3963
Query: 2927 GVLL---GISTAKVDAIGLELVDGKVLFHVNNGAGRITAAYEPKTATVLCDGKWHTLQAN 2983
GVLL G S D + L +V G + F G+G ++A L G+WH + A
Sbjct: 3964 GVLLFSGGKSGPVEDFVSLAMVGGHLEFRYELGSGLAVL----RSAEPLALGRWHRVSAE 4019
Query: 2984 KSKHRITLIVDGNAVGAESPHTQSTSVDTNNPIYVGGY-PAGVKQKCLRSQTSFRGCLRK 3042
+ +L V+G S +S ++ + +Y+GG P+ FRGC+ +
Sbjct: 4020 RLNKDGSLRVNGGRPVLRSSPGKSQGLNLHTLLYLGGVEPSVPLSPATNMSAHFRGCVGE 4079
Query: 3043 LAL 3045
+++
Sbjct: 4080 VSV 4082
Score = 70.1 bits (170), Expect = 3e-11
Identities = 54/177 (30%), Positives = 84/177 (47%), Gaps = 23/177 (12%)
Query: 2299 GSSQNEDPS-----FHFDG----SGYSVVEKSLPATVTQIIMLFNTFSPNGLLLY----L 2345
GS N+ P FH DG G+ V +SLP I + T + +GLLL+ +
Sbjct: 4192 GSGGNDAPGQYGAYFHDDGFLAFPGH-VFSRSLPEVPETIELEVRTSTASGLLLWQGVEV 4250
Query: 2346 GSYGT-KDFLSIELFRGRVKVMTDLGSGPITLLTDRRYNNGTWYKIAFQRNRKQGVLAVI 2404
G G KDF+S+ L G + LGSG L+++ N+G W+++ R ++G + V
Sbjct: 4251 GEAGQGKDFISLGLQDGHLVFRYQLGSGEARLVSEDPINDGEWHRVTALREGRRGSIQV- 4309
Query: 2405 DAYNTSNKETKQGETPGASSDLNRLDKDPIYVGGLPRSRVVRRGVTTKSFVGCIKNL 2461
+E G +PG + +N K +Y+GG P + G + GC+KNL
Sbjct: 4310 -----DGEELVSGRSPGPNVAVNA--KGSVYIGGAPDVATLTGGRFSSGITGCVKNL 4359
Score = 64.3 bits (155), Expect = 2e-09
Identities = 51/147 (34%), Positives = 59/147 (40%), Gaps = 24/147 (16%)
Query: 916 LETGLCDCKPNVTGQQCDQCLHGY----YGLDSGHGCRPCNCSVAGSVSDGCTDE-GQC- 969
LE C C P G C C GY GL GH C C C+ SD C E G C
Sbjct: 1525 LEVEECRCPPGYIGLSCQDCAPGYTRTGSGLYLGH-CELCECN---GHSDLCHPETGACS 1580
Query: 970 HCVPGVAGKRCDRCAHGFY----AYQDGSCTPCDCPHT------QNTCDPETG---EC-V 1015
C AG+ C+ CA G+Y A C PC CP T TC+ C
Sbjct: 1581 QCQHNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTA 1640
Query: 1016 CPPHTQGVKCEECEDGHWGYDAEVGCQ 1042
C P G CE+C G+ G + G Q
Sbjct: 1641 CEPGYTGQYCEQCGPGYVGNPSVQGGQ 1667
Score = 63.5 bits (153), Expect = 3e-09
Identities = 40/146 (27%), Positives = 67/146 (45%), Gaps = 6/146 (4%)
Query: 2728 FNQSAVRKKLSVELSIRTFASSGLIYYMAHQ-----NQADYAVLQLHGGRLHFMFDLGKG 2782
F++S ++EL +RT +SGL+ + + D+ L L G L F + LG G
Sbjct: 4219 FSRSLPEVPETIELEVRTSTASGLLLWQGVEVGEAGQGKDFISLGLQDGHLVFRYQLGSG 4278
Query: 2783 RTKVSHPALLSDGKWHTVKTDYVKRKGFITVDGRESPMVTVVGDGTMLDVEGLFYLGGLP 2842
++ ++DG+WH V R+G I VDG E G ++ +G Y+GG P
Sbjct: 4279 EARLVSEDPINDGEWHRVTALREGRRGSIQVDGEELVSGRSPGPNVAVNAKGSVYIGGAP 4338
Query: 2843 SQYQARKIGNITHSIPACIGDVTVNS 2868
G + I C+ ++ ++S
Sbjct: 4339 -DVATLTGGRFSSGITGCVKNLVLHS 4363
Score = 59.7 bits (143), Expect = 4e-08
Identities = 46/168 (27%), Positives = 73/168 (43%), Gaps = 13/168 (7%)
Query: 2887 AVAQEGTYFDGSGYAALVKEGYK---VQSDVNITLEFRTSSQNGVLL--GISTAKV---- 2937
A Q G YF G+ A + + I LE RTS+ +G+LL G+ +
Sbjct: 4198 APGQYGAYFHDDGFLAFPGHVFSRSLPEVPETIELEVRTSTASGLLLWQGVEVGEAGQGK 4257
Query: 2938 DAIGLELVDGKVLFHVNNGAGRITAAYEPKTATVLCDGKWHTLQANKSKHRITLIVDGNA 2997
D I L L DG ++F G+G E + DG+WH + A + R ++ VDG
Sbjct: 4258 DFISLGLQDGHLVFRYQLGSGEARLVSEDP----INDGEWHRVTALREGRRGSIQVDGEE 4313
Query: 2998 VGAESPHTQSTSVDTNNPIYVGGYPAGVKQKCLRSQTSFRGCLRKLAL 3045
+ + + +V+ +Y+GG P R + GC++ L L
Sbjct: 4314 LVSGRSPGPNVAVNAKGSVYIGGAPDVATLTGGRFSSGITGCVKNLVL 4361
Score = 52.4 bits (124), Expect = 7e-06
Identities = 35/117 (29%), Positives = 55/117 (47%), Gaps = 14/117 (11%)
Query: 2141 TLTLNVKTQEPDNLLFYLG-----SSTASDFLAVEMRRGRVAFLWDLGSGSTRLEFPDFP 2195
T+ L V+T LL + G + DF+++ ++ G + F + LGSG RL D P
Sbjct: 4229 TIELEVRTSTASGLLLWQGVEVGEAGQGKDFISLGLQDGHLVFRYQLGSGEARLVSED-P 4287
Query: 2196 IDDNRWHSIHVARFGNIGSLSVKEMSSNQKSPTKTSKSPGTANVLDVNNSTLMFVGG 2252
I+D WH + R G GS+ V ++ + S P A VN +++GG
Sbjct: 4288 INDGEWHRVTALREGRRGSIQV----DGEELVSGRSPGPNVA----VNAKGSVYIGG 4336
Score = 50.8 bits (120), Expect = 2e-05
Identities = 42/147 (28%), Positives = 64/147 (43%), Gaps = 19/147 (12%)
Query: 2328 QIIMLFNTFSPNGLLLYLGSYGTK-----------DFLSIELFRGRVKVMTDLGSGPITL 2376
+I + F S +G+LLY G DF+S L GR + D GSG T+
Sbjct: 3687 EIKITFRPDSADGMLLYNGQKRVPGSPTNLANRQPDFISFGLVGGRPEFRFDAGSGMATI 3746
Query: 2377 LTDRRYNNGTWYKIAFQRNRKQGVLAVIDAYNTSNKETKQGETPGASSDLNRLDKDPIYV 2436
G ++ + R+ QG L V D + T QG+ G DLN + +Y+
Sbjct: 3747 RHPTPLALGHFHTVTLLRSLTQGSLIVGDLAPVNG--TSQGKFQGL--DLN----EELYL 3798
Query: 2437 GGLPRSRVVRRGVTTKSFVGCIKNLEI 2463
GG P + + + F+GC++ L I
Sbjct: 3799 GGYPDYGAIPKAGLSSGFIGCVRELRI 3825
Score = 49.3 bits (116), Expect = 6e-05
Identities = 32/118 (27%), Positives = 50/118 (42%), Gaps = 20/118 (16%)
Query: 1043 ACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGYRDFP------DCVPCDCDLRG 1096
A + ++ +T H C+C + G +C+ C + P C C+C+
Sbjct: 711 AMDTTVTHATSHGRAHSVEECRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCNCNGHA 770
Query: 1097 TSGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTF--ALRADNPLGCSPCFC 1152
+S C+ G C C+ N GPQCN+C+ G F A++A C PC C
Sbjct: 771 SS---CDPVYGHC--------LNCQHNTEGPQCNKCKAGFFGDAMKA-TATSCRPCPC 816
Score = 48.9 bits (115), Expect = 8e-05
Identities = 38/147 (25%), Positives = 67/147 (45%), Gaps = 11/147 (7%)
Query: 2333 FNTFSPNGLLLYLG--SYGTKDFLSIELFRGRVKVMTDLGSGPITLLTDRRYNNGTWYKI 2390
F +P+G+LL+ G S +DF+S+ + G ++ +LGSG L + G W+++
Sbjct: 3957 FKPLAPDGVLLFSGGKSGPVEDFVSLAMVGGHLEFRYELGSGLAVLRSAEPLALGRWHRV 4016
Query: 2391 AFQRNRKQGVLAVIDAYNTSNKETKQGETPGASSDLNRLDKDPIYVGGLPRSRVVRRGVT 2450
+ +R K G L V + +PG S LN +Y+GG+ S +
Sbjct: 4017 SAERLNKDGSLRV------NGGRPVLRSSPGKSQGLNL--HTLLYLGGVEPSVPLSPATN 4068
Query: 2451 TKS-FVGCIKNLEISRSTFDLLRNSYG 2476
+ F GC+ + ++ DL + G
Sbjct: 4069 MSAHFRGCVGEVSVNGKRLDLTYSFLG 4095
Score = 47.4 bits (111), Expect = 2e-04
Identities = 44/168 (26%), Positives = 73/168 (43%), Gaps = 23/168 (13%)
Query: 2894 YFDGSGYAAL----VKEGYKVQSDVNITLEFRTSSQNGVLL------------GISTAKV 2937
YF + Y+ L +K+ Y+ I + FR S +G+LL ++ +
Sbjct: 3665 YFTQTPYSFLPLPTIKDAYR---KFEIKITFRPDSADGMLLYNGQKRVPGSPTNLANRQP 3721
Query: 2938 DAIGLELVDGKVLFHVNNGAGRITAAYEPKTATVLCDGKWHTLQANKSKHRITLIVDGNA 2997
D I LV G+ F + G+G T + T L G +HT+ +S + +LIV A
Sbjct: 3722 DFISFGLVGGRPEFRFDAGSGMATIRHP----TPLALGHFHTVTLLRSLTQGSLIVGDLA 3777
Query: 2998 VGAESPHTQSTSVDTNNPIYVGGYPAGVKQKCLRSQTSFRGCLRKLAL 3045
+ + +D N +Y+GGYP + F GC+R+L +
Sbjct: 3778 PVNGTSQGKFQGLDLNEELYLGGYPDYGAIPKAGLSSGFIGCVRELRI 3825
Score = 38.5 bits (88), Expect = 0.10
Identities = 33/114 (28%), Positives = 48/114 (42%), Gaps = 20/114 (17%)
Query: 1428 GDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGDHDFRCDACLLGYEGKH 1487
G D+ S + G D + C P TC+ G+++F+C C G++G
Sbjct: 4084 GKRLDLTYSFLGSQGIGQCYDSSPC---ERQPCQHGATCMPAGEYEFQC-LCRDGFKGDL 4139
Query: 1488 CERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDE 1541
CE + NP CQ + HG G C T +C+C G SG RC +
Sbjct: 4140 CE-----HEENP------CQLREPCLHG---GTCQGT--RCLCLPGFSGPRCQQ 4177
Score = 36.6 bits (83), Expect = 0.39
Identities = 54/243 (22%), Positives = 91/243 (37%), Gaps = 52/243 (21%)
Query: 2075 EIQANLLFDRLKPLKMLEENLSRNLSEIKLLISQARKQAASIKVAVSADRDC-IRAYQ-- 2131
+I + L L P LE N+ L++ R Q A V + +R ++A+
Sbjct: 3605 DISWSKLDGSLPPDSRLENNM--------LMLPSVRPQDAGTYVCTATNRQGKVKAFAHL 3656
Query: 2132 -------PQISSTNYNTLTL--------------NVKTQEPDNLLFYLG----------- 2159
P + T Y+ L L + D +L Y G
Sbjct: 3657 QVPERVVPYFTQTPYSFLPLPTIKDAYRKFEIKITFRPDSADGMLLYNGQKRVPGSPTNL 3716
Query: 2160 SSTASDFLAVEMRRGRVAFLWDLGSGSTRLEFPDFPIDDNRWHSIHVARFGNIGSLSVKE 2219
++ DF++ + GR F +D GSG + P P+ +H++ + R GSL V +
Sbjct: 3717 ANRQPDFISFGLVGGRPEFRFDAGSGMATIRHPT-PLALGHFHTVTLLRSLTQGSLIVGD 3775
Query: 2220 MSSNQKSPTKTSKSPGTANVLDVNNSTLMFVGGLGGQIKKSPAVKVTHFKGCLGEAFLNG 2279
++ S G LD+N +++GG A + F GC+ E + G
Sbjct: 3776 LA------PVNGTSQGKFQGLDLNEE--LYLGGYPDYGAIPKAGLSSGFIGCVRELRIQG 3827
Query: 2280 KSI 2282
+ I
Sbjct: 3828 EEI 3830
Score = 35.0 bits (79), Expect = 1.1
Identities = 19/63 (30%), Positives = 24/63 (38%), Gaps = 10/63 (15%)
Query: 1479 CLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLR 1538
C G+ G CE + + C C P + D C C LG SGLR
Sbjct: 3871 CPAGFTGSRCEHSQALH----------CHPEACGPDATCVNRPDGRGYTCRCHLGRSGLR 3920
Query: 1539 CDE 1541
C+E
Sbjct: 3921 CEE 3923
Score = 34.3 bits (77), Expect = 2.0
Identities = 30/112 (26%), Positives = 37/112 (33%), Gaps = 16/112 (14%)
Query: 940 YGLDSGHGCRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCDRCAHGFYAYQDGSCTPCD 999
+G+ CR C G D + C C G G RC+ Q C P
Sbjct: 3840 HGISHCPTCRDRPCQNGGQCHDSESSSYVCVCPAGFTGSRCEHS-------QALHCHP-- 3890
Query: 1000 CPHTQNTCDPETGECVCPPHTQGVKCEECEDGHWGYDAEVGCQACNCSLVGS 1051
C P+ CV P +G C C G G E G SL G+
Sbjct: 3891 -----EACGPD-ATCVNRPDGRGYTC-RCHLGRSGLRCEEGVTVTTPSLSGA 3935
Score = 34.3 bits (77), Expect = 2.0
Identities = 42/174 (24%), Positives = 75/174 (43%), Gaps = 30/174 (17%)
Query: 2494 GGYIELPPKSLSPESEWL-VTFATTNSSGIILAALGGDVEKRGDREEAHVPFFSVMLIGG 2552
G Y+ LP + + L V F G++L + G K G E+ F S+ ++GG
Sbjct: 3936 GSYLALPALTNTHHELRLDVEFKPLAPDGVLLFSGG----KSGPVED----FVSLAMVGG 3987
Query: 2553 NIEVHVNPGDGTGLRKALLHAPTGTCSDGQAHSISLVRNRRIITVQLDENNPVEMKLGTL 2612
++E G G + ++ A ++L R R+ +L+++ + + G
Sbjct: 3988 HLEFRYELGSGLAVLRS-------------AEPLALGRWHRVSAERLNKDGSLRVNGGRP 4034
Query: 2613 V------ESRTINVSN-LYVGGIPEGEGTSLLT-MRRSFHGCIKNLIFNLELLD 2658
V +S+ +N+ LY+GG+ S T M F GC+ + N + LD
Sbjct: 4035 VLRSSPGKSQGLNLHTLLYLGGVEPSVPLSPATNMSAHFRGCVGEVSVNGKRLD 4088
>gi|167614504 laminin, beta 1 precursor [Homo sapiens]
Length = 1786
Score = 338 bits (866), Expect = 6e-92
Identities = 309/1227 (25%), Positives = 480/1227 (39%), Gaps = 274/1227 (22%)
Query: 17 CRQRGLFPAI--LNLASNAHISTNATCGEKGPEMFCKLVEHVPGRPVRNPQCRICDGNSA 74
C + +PA L + +S +TCG PE +C +V H+ + +C IC+
Sbjct: 30 CAEGSCYPATGDLLIGRAQKLSVTSTCGLHKPEPYC-IVSHLQ----EDKKCFICNSQDP 84
Query: 75 NPRERHPISHAIDGTNN---------WWQSPSIQNGREYHWVTITLDLRQVFQVAYVIIK 125
+P SH I+ WWQS +NG E VTI LDL F ++I+
Sbjct: 85 YHETLNPDSHLIENVVTTFAPNRLKIWWQS---ENGVEN--VTIQLDLEAEFHFTHLIMT 139
Query: 126 AANAPRPGNWILERSLD-GTTFSPWQYYA-----------------VSDSECLSRYN-IT 166
RP ++ERS D G T+ ++Y+A V D C SRY+ I
Sbjct: 140 FKTF-RPAAMLIERSSDFGKTWGVYRYFAYDCEASFPGISTGPMKKVDDIICDSRYSDIE 198
Query: 167 PR-RGPPTYRADDEV--ICTSYYSRLVPL-EHGEIHTSLINGRPSADDLSPKLLEFTSAR 222
P G +RA D I Y R+ L + + + D+L +E
Sbjct: 199 PSTEGEVIFRALDPAFKIEDPYSPRIQNLLKITNLRIKFVKLHTLGDNLLDSRMEIREKY 258
Query: 223 YIRLRLQRIRT----------------LNADLMTLSH------REPKELDPIVTRRYYYS 260
Y + +R N ++ + H K L+ + +Y+
Sbjct: 259 YYAVYDMVVRGNCFCYGHASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHD 318
Query: 261 I-------KDISVGGMCICYGHASSCPWD--------ETTKKLQCQCEHNTCGESCNRCC 305
+ ++ + C C H+ SC +D + + C+HNT G +C +C
Sbjct: 319 LPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCK 378
Query: 306 PGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKSLNT---AGQFRGGGVCI 362
P Y+Q P R + N CE C C +E + +T AGQ R
Sbjct: 379 PFYYQHPERD--IRDPNFCERCTCDPAGSQ---NEGICDSYTDFSTGLIAGQCR------ 427
Query: 363 NCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSS--------------- 407
C N G +C+ C +G+Y P+ C+ C C+P+G++
Sbjct: 428 -CKLNVEGEHCDVCKEGFYDLSSEDPFG---CKSCACNPLGTIPGGNPCDSETGHCYCKR 483
Query: 408 --------VCIKD----------------DLHSDLHNG--KQPGQCPCKEGYTGEKCDRC 441
C+ + DL L+N + GQC C+ G +C+
Sbjct: 484 LVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEV 543
Query: 442 QLGYKDYPTCVSCGCNPVGSASDEPCTGPCVC---KENVEGKACDRCKPGFYNLKEKNPR 498
+ GY + ++E GP V ++ ++ + GF + E
Sbjct: 544 EPGY------YFATLDHYLYEAEEANLGPGVSIVERQYIQDRIPSWTGAGFVRVPE---- 593
Query: 499 GCSECFCFGVSDVCSSLSWPV-----GQVNSMSGWLVTDLISPRKIPSQQDALGGRHQVS 553
F + ++ S+ + + Q+ V + P +IP+ + +
Sbjct: 594 --GAYLEFFIDNIPYSMEYDILIRYEPQLPDHWEKAVITVQRPGRIPTSSRC---GNTIP 648
Query: 554 INNTAVMQRLAPKYYWAAPEAYLGNKLTAFGGFLKYTVSYDIPVETV-DSNLMSHADVII 612
++ V+ Y P K T YTV ++P T DS++ S +I
Sbjct: 649 DDDNQVVSLSPGSRYVVLPRPVCFEKGT------NYTVRLELPQYTSSDSDVESPYTLI- 701
Query: 613 KGNGLTLSTQAEGLSLQPYEEYLNVVRL-----------VPENFQDFH---SKRQIDRDQ 658
+ L L PY + L++ + E FQ + + R + +
Sbjct: 702 -----------DSLVLMPYCKSLDIFTVGGSGDGVVTNSAWETFQRYRCLENSRSVVKTP 750
Query: 659 LMTVLANVTHLLIRANYNSAKMALYRLESVSLDIASSNAIDLVVAADVEHCECPQGYTGT 718
+ V N+ + AL ++ + ++ V + C+C G
Sbjct: 751 MTDVCRNIIFSI---------SALLHQTGLACECDPQGSLSSVCDPNGGQCQCRPNVVGR 801
Query: 719 SCESCLSGYYRVDGILFGGI-CQPCECH-------------------------------- 745
+C C G + FG C+PCECH
Sbjct: 802 TCNRCAPGTFG-----FGPSGCKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLP 856
Query: 746 --------------GHAAECN-VHGVCIACAHNTTGVHCEQCLPGFYGEPSRGTPGDCQP 790
GHA +C+ V G C+ C T G +CE+CL G+YG+P G+ C+P
Sbjct: 857 GHWGFPSCQPCQCNGHADDCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRP 916
Query: 791 CACP-LTIASNNFSPTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNPTVPGESCVPC 849
C CP + F+ +C+ + + C PGY G+ C+ CA GY+GNP+ G SC PC
Sbjct: 917 CPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPC 976
Query: 850 DCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCADGFYGDAVTAKNCRACECHVKGS 909
C N+D ++ CD TG CLKCL +T+G HC+ C G+YGDA+ ++CR C C+ G+
Sbjct: 977 QCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYYGDAL-QQDCRKCVCNYLGT 1035
Query: 910 -------HSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLDSGHGCRPCNCSVAGSVSDG 962
C TG C C PNV GQ CD+C + L SG GC PCNC+ A S
Sbjct: 1036 VQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQLASGTGCDPCNCNAAHSFGPS 1095
Query: 963 CTD-EGQCHCVPGVAGKRCDRCAHGFYAYQDGSCTPCDC-PHTQNT--CDPETGECVCPP 1018
C + GQC C+PG G+ C C F+ D C CDC P T CD TG+CVC
Sbjct: 1096 CNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRACDCDPRGIETPQCDQSTGQCVCVE 1155
Query: 1019 HTQGVKCEECEDGHWGYDAEVGCQACN 1045
+G +C++C G+ G + C C+
Sbjct: 1156 GVEGPRCDKCTRGYSGVFPD--CTPCH 1180
Score = 246 bits (628), Expect = 3e-64
Identities = 152/469 (32%), Positives = 204/469 (43%), Gaps = 86/469 (18%)
Query: 742 CECHGH---AAECNVHGVCIACAHNTTGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIA 798
CEC ++ C+ +G C N G C +C PG +G P C+PC C L +
Sbjct: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFG----PSGCKPCECHLQGS 828
Query: 799 SNNF----SPTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNPTVPGESCVPCDCSGN 854
N F + CH C G C+RC G++G P SC PC C+G+
Sbjct: 829 VNAFCNPVTGQCH-----------CFQGVYARQCDRCLPGHWGFP-----SCQPCQCNGH 872
Query: 855 VDPSEAGHCDSVTGECLKCLGNTDGAHCERCADGFYGDAV--TAKNCRACEC-------- 904
D CD VTGECL C T G +CERC G+YGD + + +CR C C
Sbjct: 873 ADD-----CDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGR 927
Query: 905 -HVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLDS--GHGCRPCNC--SVAGSV 959
+ + L+ C C P G +CD C GY+G S G C+PC C ++ +
Sbjct: 928 QFARSCYQDPVTLQLA-CVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTD 986
Query: 960 SDGCTDE-GQC-HCVPGVAGKRCDRCAHGFYA---YQDGSCTPCDCPHTQNT-------- 1006
+ C E G+C C+ G+ C C G+Y QD C C C +
Sbjct: 987 PEACDKETGRCLKCLYHTEGEHCQFCRFGYYGDALQQD--CRKCVCNYLGTVQEHCNGSD 1044
Query: 1007 --CDPETGECVCPPHTQGVKCEECEDGHWGYDAEVGCQACNCSLVGSTHHRCDVVTGHCQ 1064
CD TG+C+C P+ G C+ C W + GC CNC+ S C+ TG CQ
Sbjct: 1045 CQCDKATGQCLCLPNVIGQNCDRCAPNTWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQ 1104
Query: 1065 CKSKFGGRACDQCSLGYRDFPD--CVPCDCDLRGTSGDACNLEQGLCGCVEETGACPCKE 1122
C FGGR C +C + PD C CDCD RG C+ + TG C C E
Sbjct: 1105 CMPGFGGRTCSECQELFWGDPDVECRACDCDPRGIETPQCD---------QSTGQCVCVE 1155
Query: 1123 NVFGPQCNECREGTFALRADNPLGCSPCFCSGLSHLCSELEDYVRTPVT 1171
V GP+C++C G + D C+PC H C L D + +T
Sbjct: 1156 GVEGPRCDKCTRGYSGVFPD----CTPC------HQCFALWDVIIAELT 1194
Score = 172 bits (435), Expect = 6e-42
Identities = 105/322 (32%), Positives = 139/322 (43%), Gaps = 75/322 (23%)
Query: 901 ACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLDSGHGCRPCNCSVAGSVS 960
ACEC +GS S+VC G C C+PNV G+ C++C G +G GC+PC C + GSV+
Sbjct: 772 ACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPS-GCKPCECHLQGSVN 830
Query: 961 DGCTD-EGQCHCVPGVAGKRCDRCAHGFYAYQDGSCTPCDCPHTQNTCDPETGECV-CPP 1018
C GQCHC GV ++CDRC G + + SC PC C + CDP TGEC+ C
Sbjct: 831 AFCNPVTGQCHCFQGVYARQCDRCLPGHWGFP--SCQPCQCNGHADDCDPVTGECLNCQD 888
Query: 1019 HTQGVKCEECEDGHWGYDAEVG----CQACNC--------SLVGSTHHRCDVVTGHCQCK 1066
+T G CE C G++G D +G C+ C C S + + C C
Sbjct: 889 YTMGHNCERCLAGYYG-DPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCD 947
Query: 1067 SKFGGRACDQCSLGYRDFP-----DCVPCDC--DLRGTSGDACNLEQGLC---------- 1109
+ G CD C+ GY P C PC C ++ T +AC+ E G C
Sbjct: 948 PGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGE 1007
Query: 1110 --------------------------GCVEE------------TGACPCKENVFGPQCNE 1131
G V+E TG C C NV G C+
Sbjct: 1008 HCQFCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDR 1067
Query: 1132 CREGTFALRADNPLGCSPCFCS 1153
C T+ L + GC PC C+
Sbjct: 1068 CAPNTWQLASGT--GCDPCNCN 1087
Score = 162 bits (409), Expect = 6e-39
Identities = 183/844 (21%), Positives = 321/844 (38%), Gaps = 134/844 (15%)
Query: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDT-----CDPNT 1416
CVC PG +G C DCA GY G C PC C+N+ DT CD T
Sbjct: 944 CVCDPGYIGSRCDDCASGYFGNPSEVGGS---------CQPCQCHNNIDTTDPEACDKET 994
Query: 1417 GKCLNCGDNTAGDHCDVCTSGYYG------------------------------KVTGSA 1446
G+CL C +T G+HC C GYYG K TG
Sbjct: 995 GRCLKCLYHTEGEHCQFCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQC 1054
Query: 1447 --------SDCALCA--------------CPHSPPASFSPTCVLEGDHDFRCDACLLGYE 1484
+C CA C + SF P+C + +C C+ G+
Sbjct: 1055 LCLPNVIGQNCDRCAPNTWQLASGTGCDPCNCNAAHSFGPSC---NEFTGQCQ-CMPGFG 1110
Query: 1485 GKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDECEP 1544
G+ C C ++G+P C+ CDC+P G CD+++GQCVC G G RCD+C
Sbjct: 1111 GRTCSECQELFWGDPDV---ECRACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTR 1167
Query: 1545 RHILMETDCVSCD------DECVGVLLNDLDEIGDAVLSLNLTGIIPVPYGILSNLENTT 1598
+ + DC C D + L N + +L ++G+I + ++E
Sbjct: 1168 GYSGVFPDCTPCHQCFALWDVIIAELTNRTHRFLEKAKALKISGVIGPYRETVDSVERKV 1227
Query: 1599 KYLQESLLKENMQKDLGKIKLEGVAEETDNLQKKLTRMLASTQ-KVNRATER---IFKES 1654
+++ L + + L I + EE + L K +T M+A + K++ T + KE
Sbjct: 1228 SEIKDILAQSPAAEPLKNI--GNLFEEAEKLIKDVTEMMAQVEVKLSDTTSQSNSTAKEL 1285
Query: 1655 QDLAIAIERLQMSITEIMEKTTLNQTLDEDFLLPNSTLQNMQQNGTSLLEIMQIRDFTQL 1714
L E L ++ E+ E+ + D L ++ + LE + + +
Sbjct: 1286 DSLQTEAESLDNTVKELAEQLEFIKNSD-----IRGALDSITKYFQMSLEAEERVNASTT 1340
Query: 1715 HQNATLELKA-----AEDLLSQIQENY-QKPLEELEVLKEAASHVLSKHNNELKAAEALV 1768
N+T+E A ED++ + + + +K E+ +L E A + S +L AA +
Sbjct: 1341 EPNSTVEQSALMRDRVEDVMMERESQFKEKQEEQARLLDELAGKLQSL---DLSAAAEMT 1397
Query: 1769 REAEAKMQESNHLLLMVNANLREFSDKKLHVQEEQNLTSELIVQGRGLIDAAAAQ--TDA 1826
+ + E E + G + A Q D
Sbjct: 1398 CGTPPG----------ASCSETECGGPNCRTDEGERKCGGPGCGGLVTVAHNAWQKAMDL 1447
Query: 1827 VQDALEHL-EDHQDKLLLWSAKIRHHIDDLVMHMSQRNAVDLVYRAEDHAAEFQRLADVL 1885
QD L L E Q ++ AK+R ++++A D++ + + + + L
Sbjct: 1448 DQDVLSALAEVEQLSKMVSEAKLR-------ADEAKQSAEDILLKTNATKEKMDKSNEEL 1500
Query: 1886 YSGLENIRNV---------SLNATSAAYVHYNIQSLIEESEELARDAHRTVTETSLLSES 1936
+ ++ IRN S+ A + + + S ++ + L D V S + E
Sbjct: 1501 RNLIKQIRNFLTQDSADLDSIEAVANEVLKMEMPSTPQQLQNLTEDIRERVESLSQV-EV 1559
Query: 1937 LVSNGKAAVQRSSRFLKEGNNLSRKLPGIALE---LSELRNKTNRFQENAVEITRQTNES 1993
++ + A + R+ L+E S+ + + + E + + Q A + +Q +E
Sbjct: 1560 ILQHSAADIARAEMLLEEAKRASKSATDVKVTADMVKEALEEAEKAQVAAEKAIKQADED 1619
Query: 1994 LLILRAIPKGIRDKGAKTKELATSASQSAVSTLRDVAGLSQELLNTSASLSRVNTTLRET 2053
+ + + I + A ++E +ASQ R+V L ++ S + +
Sbjct: 1620 IQGTQNLLTSIESETAASEETLFNASQRISELERNVEELKRKAAQNSGEAEYIEKVVYTV 1679
Query: 2054 HQLLQDSTMATLLAGRKVKDVEIQANLLFDRLKPLKMLEENLSRNLSEIKLLISQARKQA 2113
Q +D + L G + + NL+ + + +E K L++QA +
Sbjct: 1680 KQSAED--VKKTLDGELDEKYKKVENLIAKKTEESADARRKAEMLQNEAKTLLAQANSKL 1737
Query: 2114 ASIK 2117
+K
Sbjct: 1738 QLLK 1741
Score = 141 bits (356), Expect = 9e-33
Identities = 84/279 (30%), Positives = 118/279 (42%), Gaps = 54/279 (19%)
Query: 846 CVPCD-CSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCADGFY------GDAVTAKN 898
C P D + V+ GHC C NT G +CE C D ++ + +
Sbjct: 280 CAPVDGFNEEVEGMVHGHC--------MCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNA 331
Query: 899 CRACECHVKGSHSAVCHLET-----------GLCD-CKPNVTGQQCDQCLHGYY-----G 941
C+ C C+ HS CH + G+CD C+ N G+ C+QC YY
Sbjct: 332 CKKCNCN---EHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERD 388
Query: 942 LDSGHGCRPCNCSVAGSVSDGCTDE----------GQCHCVPGVAGKRCDRCAHGFY--- 988
+ + C C C AGS ++G D GQC C V G+ CD C GFY
Sbjct: 389 IRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLS 448
Query: 989 -----AYQDGSCTPCDCPHTQNTCDPETGECVCPPHTQGVKCEECEDGHWGYDAEV-GCQ 1042
+ +C P N CD ETG C C G C++C HWG ++ GC+
Sbjct: 449 SEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGCR 508
Query: 1043 ACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGY 1081
C+C L G+ ++ C +G C C+ GR C++ GY
Sbjct: 509 PCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGY 547
Score = 134 bits (336), Expect = 2e-30
Identities = 73/205 (35%), Positives = 95/205 (46%), Gaps = 26/205 (12%)
Query: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKCLN 1421
C C G C C PG H G C PC CN H+D CDP TG+CLN
Sbjct: 840 CHCFQGVYARQCDRCLPG-HWG-------------FPSCQPCQCNGHADDCDPVTGECLN 885
Query: 1422 CGDNTAGDHCDVCTSGYYG-KVTGSASDCALCACPHSPPA--SFSPTCVLEGDHDFRCDA 1478
C D T G +C+ C +GYYG + GS C C CP P + F+ +C +
Sbjct: 886 CQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACV 945
Query: 1479 CLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGD----CDRTSGQCV-CRLG 1533
C GY G C+ C+S Y+GNP GGSCQ C C H ++ CD+ +G+C+ C
Sbjct: 946 CDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQC--HNNIDTTDPEACDKETGRCLKCLYH 1003
Query: 1534 ASGLRCDECEPRHI--LMETDCVSC 1556
G C C + ++ DC C
Sbjct: 1004 TEGEHCQFCRFGYYGDALQQDCRKC 1028
Score = 132 bits (332), Expect = 5e-30
Identities = 87/306 (28%), Positives = 130/306 (42%), Gaps = 65/306 (21%)
Query: 892 DAVTAKNC----RACECH-VKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLD--- 943
D V NC A EC V G + V + G C C+ N G C+ C+ Y+ L
Sbjct: 264 DMVVRGNCFCYGHASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRP 323
Query: 944 ----SGHGCRPCNCS--------------VAGSVSDGCTDEGQCHCVPGVAGKRCDRCAH 985
+ + C+ CNC+ G+VS G D+ C G+ C++C
Sbjct: 324 AEGRNSNACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDD----CQHNTMGRNCEQCKP 379
Query: 986 GFYAYQDGS------CTPCDCP----HTQNTCDPET--------GECVCPPHTQGVKCEE 1027
+Y + + C C C + CD T G+C C + +G C+
Sbjct: 380 FYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDV 439
Query: 1028 CEDGHWGYDAE--VGCQACNCSLVGSTH--HRCDVVTGHCQCKSKFGGRACDQCSLGY-- 1081
C++G + +E GC++C C+ +G+ + CD TGHC CK G+ CDQC +
Sbjct: 440 CKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWG 499
Query: 1082 --RDFPDCVPCDCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFAL 1139
D C PCDCDL G ++ C E+G C C+ ++ G QCNE G +
Sbjct: 500 LSNDLDGCRPCDCDLGGALNNS---------CFAESGQCSCRPHMIGRQCNEVEPGYYFA 550
Query: 1140 RADNPL 1145
D+ L
Sbjct: 551 TLDHYL 556
Score = 109 bits (272), Expect = 5e-23
Identities = 73/241 (30%), Positives = 101/241 (41%), Gaps = 35/241 (14%)
Query: 1353 EEVASLLE-NCVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDT 1411
EEV ++ +C+C T G +C+ C YH LP G C C+CN HS +
Sbjct: 288 EEVEGMVHGHCMCRHNTKGLNCELCMDFYH--DLPWRPAEGRNS--NACKKCNCNEHSIS 343
Query: 1412 C-----------DPNTGKCLNCGDNTAGDHCDVCTSGYYGKVTGSASD---CALCACPHS 1457
C + + G C +C NT G +C+ C YY D C C C
Sbjct: 344 CHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTC--- 400
Query: 1458 PPASFSPTCVLEGDHDF-------RCDACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCD 1510
PA + + DF +C C L EG+HC+ C +Y C+ C
Sbjct: 401 DPAGSQNEGICDSYTDFSTGLIAGQC-RCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCA 459
Query: 1511 CNPHGSVHG--DCDRTSGQCVCRLGASGLRCDECEPRHILMETD---CVSCDDECVGVLL 1565
CNP G++ G CD +G C C+ +G CD+C P H + D C CD + G L
Sbjct: 460 CNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALN 519
Query: 1566 N 1566
N
Sbjct: 520 N 520
Score = 103 bits (258), Expect = 2e-21
Identities = 77/286 (26%), Positives = 105/286 (36%), Gaps = 77/286 (26%)
Query: 276 ASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKD 335
A SC D T +L C C+ G C+ C GY P G +C+ C CHN D
Sbjct: 930 ARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNP-----SEVGGSCQPCQCHNNI-D 983
Query: 336 CYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCR 395
E+ K+ G C+ CL +T G +C+ C GYY + CR
Sbjct: 984 TTDPEACDKET------------GRCLKCLYHTEGEHCQFCRFGYY-----GDALQQDCR 1026
Query: 396 PCNCDPVGSLSSVCIKDDLHSDLHNGKQ-------------------------------- 423
C C+ +G++ C D D G+
Sbjct: 1027 KCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQLASGTGCDPCNC 1086
Query: 424 -------------PGQCPCKEGYTGEKCDRCQLGYKDYPT--CVSCGCNPVGSASDE--P 466
GQC C G+ G C CQ + P C +C C+P G + +
Sbjct: 1087 NAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRACDCDPRGIETPQCDQ 1146
Query: 467 CTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECF-CFGVSDV 511
TG CVC E VEG CD+C G+ + C+ C CF + DV
Sbjct: 1147 STGQCVCVEGVEGPRCDKCTRGYSGVFP----DCTPCHQCFALWDV 1188
Score = 99.0 bits (245), Expect = 6e-20
Identities = 70/242 (28%), Positives = 101/242 (41%), Gaps = 28/242 (11%)
Query: 1364 CPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCN----NHSDTCDPNT--- 1416
C T+G +C+ C P Y++ P R P C C+C+ + CD T
Sbjct: 365 CQHNTMGRNCEQCKPFYYQH--PERDIRDPNF----CERCTCDPAGSQNEGICDSYTDFS 418
Query: 1417 -----GKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGD 1471
G+C C N G+HCDVC G+Y + C CAC C E
Sbjct: 419 TGLIAGQC-RCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETG 477
Query: 1472 HDFRCDACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCR 1531
H + C G+HC++C ++G G C+ CDC+ G+++ C SGQC CR
Sbjct: 478 HCY----CKRLVTGQHCDQCLPEHWGLSNDLDG-CRPCDCDLGGALNNSCFAESGQCSCR 532
Query: 1532 LGASGLRCDECEPRHILMETDCVSCDDECV----GVLLNDLDEIGDAVLSLNLTGIIPVP 1587
G +C+E EP + D + E GV + + I D + S G + VP
Sbjct: 533 PHMIGRQCNEVEPGYYFATLDHYLYEAEEANLGPGVSIVERQYIQDRIPSWTGAGFVRVP 592
Query: 1588 YG 1589
G
Sbjct: 593 EG 594
Score = 79.3 bits (194), Expect = 5e-14
Identities = 52/175 (29%), Positives = 77/175 (44%), Gaps = 38/175 (21%)
Query: 1012 GECVCPPHTQGVKCEECEDGH----W----GYDAEVGCQACNCSLVGSTHH--------R 1055
G C+C +T+G+ CE C D + W G ++ C+ CNC+ + H
Sbjct: 296 GHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNA-CKKCNCNEHSISCHFDMAVYLAT 354
Query: 1056 CDVVTGHCQ-CKSKFGGRACDQCSLGYRDFPD--------CVPCDCDLRGTSGDACNLEQ 1106
+V G C C+ GR C+QC Y P+ C C CD G+ +
Sbjct: 355 GNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNE------ 408
Query: 1107 GLCGCVEE------TGACPCKENVFGPQCNECREGTFALRADNPLGCSPCFCSGL 1155
G+C + G C CK NV G C+ C+EG + L +++P GC C C+ L
Sbjct: 409 GICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPL 463
Score = 71.6 bits (174), Expect = 1e-11
Identities = 46/150 (30%), Positives = 62/150 (41%), Gaps = 34/150 (22%)
Query: 1403 CSCNNH---SDTCDPNTGKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPP 1459
C C+ S CDPN G+C C N G C+ C G +G S C C C
Sbjct: 773 CECDPQGSLSSVCDPNGGQC-QCRPNVVGRTCNRCAPGTFG---FGPSGCKPCECH---- 824
Query: 1460 ASFSPTCVLEGDHDFRCDA------CLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNP 1513
L+G + C+ C G + C+RC ++G P SCQ C CN
Sbjct: 825 --------LQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGFP-----SCQPCQCNG 871
Query: 1514 HGSVHGDCDRTSGQCV-CRLGASGLRCDEC 1542
H DCD +G+C+ C+ G C+ C
Sbjct: 872 HAD---DCDPVTGECLNCQDYTMGHNCERC 898
Score = 70.9 bits (172), Expect = 2e-11
Identities = 55/197 (27%), Positives = 80/197 (40%), Gaps = 36/197 (18%)
Query: 1403 CSCNNHSDTCDPNTG-----------KCLNCGDNTAGDHCDVCTSGYYG----KVTGSAS 1447
C C H+ C P G C+ C NT G +C++C Y+ G S
Sbjct: 271 CFCYGHASECAPVDGFNEEVEGMVHGHCM-CRHNTKGLNCELCMDFYHDLPWRPAEGRNS 329
Query: 1448 D-CALCAC-PHSPPASFSPTCVLEGDHDFR--CDACLLGYEGKHCERCSSSYYGNPQ--- 1500
+ C C C HS F L + CD C G++CE+C YY +P+
Sbjct: 330 NACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDI 389
Query: 1501 TPGGSCQKCDCNPHGSVH-GDCDR--------TSGQCVCRLGASGLRCDECEPRHILMET 1551
C++C C+P GS + G CD +GQC C+L G CD C+ + +
Sbjct: 390 RDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSS 449
Query: 1552 D----CVSCDDECVGVL 1564
+ C SC +G +
Sbjct: 450 EDPFGCKSCACNPLGTI 466
Score = 58.5 bits (140), Expect = 1e-07
Identities = 33/94 (35%), Positives = 44/94 (46%), Gaps = 7/94 (7%)
Query: 1453 ACPHSPPASFSPTCVLEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCN 1512
AC P S S C G +C C G+ C RC+ +G P G C+ C+C+
Sbjct: 772 ACECDPQGSLSSVCDPNGG---QCQ-CRPNVVGRTCNRCAPGTFGFG--PSG-CKPCECH 824
Query: 1513 PHGSVHGDCDRTSGQCVCRLGASGLRCDECEPRH 1546
GSV+ C+ +GQC C G +CD C P H
Sbjct: 825 LQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGH 858
>gi|143770880 laminin, beta 4 [Homo sapiens]
Length = 1761
Score = 289 bits (739), Expect = 3e-77
Identities = 138/340 (40%), Positives = 180/340 (52%), Gaps = 26/340 (7%)
Query: 709 CECPQGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAAECNVH-GVCIACAHNTTGV 767
C C +G C+ CL+GY+ C PC C+ A C+ G C C TTG
Sbjct: 836 CPCHGEVSGRRCDRCLAGYFGFPS------CHPCPCNRFAELCDPETGSCFNCGGFTTGR 889
Query: 768 HCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNN-FSPTCHLND-GDEVVCDWCAPGYSG 825
+CE+C+ G+YG PS G P C+PC CP +SN F+ +C+ N +V+C+ C GY+G
Sbjct: 890 NCERCIDGYYGNPSSGQP--CRPCLCPDDPSSNQYFAHSCYQNLWSSDVICN-CLQGYTG 946
Query: 826 AWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERC 885
C C+ G+YGNP + G C PC C+ N+D ++ C VTGECL+CL NT GA+C+ C
Sbjct: 947 TQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQLC 1006
Query: 886 ADGFYGDAVTAKNCRACECHVK---------GSHSAVCHLETGLCDCKPNVTGQQCDQCL 936
G YG A+ + CR C CH G + +C TG C C PNVTG CD+C
Sbjct: 1007 KPGHYGSALN-QTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCA 1065
Query: 937 HGYYGLDSGHGCRPCNCSVAGSVSDGCTD-EGQCHCVPGVAGKRCDRCAHGFYAYQDGSC 995
GY+ L G GC+ C+C S S C GQC C G GKRC C +Y G C
Sbjct: 1066 DGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSECQENYYGDPPGRC 1125
Query: 996 TPCDCPHT---QNTCDPETGECVCPPHTQGVKCEECEDGH 1032
PCDC + CDP+TG C C G +C+ C GH
Sbjct: 1126 IPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRCARGH 1165
Score = 275 bits (704), Expect = 4e-73
Identities = 259/1018 (25%), Positives = 373/1018 (36%), Gaps = 267/1018 (26%)
Query: 270 CICYGHASSCPWDETTKKLQ-------CQ-CEHNTCGESCNRCCPGYHQQPWRPGTVSSG 321
C C H+S C +D TT C+ C+HNT G+ C+RC P +++ P + T+S
Sbjct: 332 CSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLK--TISDP 389
Query: 322 NTCEACNCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYY 381
C C C V+ +L + G C+ C +N G C+ C +Y
Sbjct: 390 YACIPCECDPDGT-ISGGICVSHSDPALGSVA-----GQCL-CKENVEGAKCDQCKPNHY 442
Query: 382 RPHKVSPYEDEPCRPCNCDPVGSLSSVCIKDD------------------------LHSD 417
P C+PC+C+P+GSL + D L +
Sbjct: 443 GLSATDPLG---CQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLGNH 499
Query: 418 LHN----------------GKQPGQCPCKEGYTGEKCDRCQLGYKDYP----------TC 451
LH + GQC C+ TG C GY P
Sbjct: 500 LHGCSPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAPGYFFAPLNFYLYEAEEAT 559
Query: 452 VSCGCNPVGSAS--DEPCTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFCFGVS 509
G P+GS + P V E V G PGF + F V+
Sbjct: 560 TLQGLAPLGSETFGQSPAVH-VVLGEPVPGNPVTWTGPGFARVLP------GAGLRFAVN 612
Query: 510 DVCSSLSWPVG---QVNSMSGWLVTDLISPRKIPSQQDALGGRHQVSINNTAVMQRLAPK 566
++ + + + + S + W V Q+ +N + PK
Sbjct: 613 NIPFPVDFTIAIHYETQSAADWTV--------------------QIVVNPPGGSEHCIPK 652
Query: 567 YYWAAPEAYLGNKLTAFGGF-----LKYTVSYDIPV---ETVDSNLMSHADVIIKGNGLT 618
+ P+++ T L+ V Y I V + + +H+ V++ GL
Sbjct: 653 TLQSKPQSFALPAATRIMLLPTPICLEPDVQYSIDVYFSQPLQGESHAHSHVLVDSLGL- 711
Query: 619 LSTQAEGLSLQPYEEYLNVVRLVPE--NFQDFHSKRQIDRDQLMTVLANVTHLLIRANYN 676
+P+ + ++F SK+ +D QL + + + +
Sbjct: 712 ----------------------IPQINSLENFCSKQDLDEYQLHNCVEIASAMGPQVLPG 749
Query: 677 SAKMALYRLESVSLDIASSNAIDLVVAADVEHCEC-PQGYTGTSCESCLSGYYRVDGILF 735
+ + + + S+ D VA C+C PQG G+SC
Sbjct: 750 ACERLIISM--------SAKLHDGAVA-----CKCHPQGSVGSSCSR------------L 784
Query: 736 GGICQPCECHGHAAECNVHGVCIACAHNTTGVHCEQCLPGFYGEPSRGTPGDCQPCACPL 795
GG CQ C G C++C G Y G C PC C
Sbjct: 785 GGQCQ-------------------CKPLVVGRCCDRCSTGSYDLGHHG----CHPCHC-- 819
Query: 796 TIASNNFSPTCHLNDGDEVVCDW------CAPGYSGAWCERCADGYYGNPTVPGESCVPC 849
H + VCD C SG C+RC GY+G P SC PC
Sbjct: 820 -----------HPQGSKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFP-----SCHPC 863
Query: 850 DCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCADGFYGDAVTAKNCRACECHVKGS 909
C+ A CD TG C C G T G +CERC DG+YG+ + + CR C C S
Sbjct: 864 PCN-----RFAELCDPETGSCFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPCLCPDDPS 918
Query: 910 ------HSAVCHLETG--LCDCKPNVTGQQCDQCLHGYYGLD--SGHGCRPCNCSVAGSV 959
HS +L + +C+C TG QC +C G+YG SG C+PC C+ V
Sbjct: 919 SNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDV 978
Query: 960 SD--GCTD-EGQC-HCVPGVAGKRCDRCAHGFYAYQ-DGSCTPCDCPHTQNT-------- 1006
+D C+ G+C C+ G C C G Y + +C C C H
Sbjct: 979 TDPESCSRVTGECLRCLHNTQGANCQLCKPGHYGSALNQTCRRCSC-HASGVSPMECPPG 1037
Query: 1007 -----CDPETGECVCPPHTQGVKCEECEDGHWGYDAEVGCQACNCSLVGSTHHRCDVVTG 1061
CDP TG C C P+ G+ C+ C DG+W GCQ+C+C S CD +TG
Sbjct: 1038 GGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTG 1097
Query: 1062 HCQCKSKFGGRACDQCSLGYRDFPD--CVPCDCDLRGTSGDACNLEQGLCGCVEETGACP 1119
C CK +GG+ C +C Y P C+PCDC+ GT C+ +TG C
Sbjct: 1098 QCPCKLGYGGKRCSECQENYYGDPPGRCIPCDCNRAGTQKPICD---------PDTGMCR 1148
Query: 1120 CKENVFGPQCNECREGTFALRADNPLGCSPCF-------------CSGLSHLCSELED 1164
C+E V G +C+ C G + L C CF GL L + +ED
Sbjct: 1149 CREGVSGQRCDRCARG-HSQEFPTCLQCHLCFDQWDHTISSLSKAVQGLMRLAANMED 1205
Score = 233 bits (593), Expect = 3e-60
Identities = 158/521 (30%), Positives = 246/521 (47%), Gaps = 70/521 (13%)
Query: 27 LNLASNAHISTNATCGEKGPEMFCKLVEHVPGRPVRNPQCRICDGNSANPRERHPISHAI 86
L + N + ++TCG + +C ++ ++ G +C ICD P SH I
Sbjct: 35 LLVGRNTQLMASSTCGLSRAQKYC-ILSYLEGEQ----KCFICDSRFPYDPYDQPNSHTI 89
Query: 87 ---------DGTNNWWQSPSIQNGREYHWVTITLDLRQVFQVAYVIIKAANAPRPGNWIL 137
D WWQS +NG ++ V+I LDL +F+ +++I+ RP ++
Sbjct: 90 ENVIVSFEPDREKKWWQS---ENGLDH--VSIRLDLEALFRFSHLILTFKTF-RPAAMLV 143
Query: 138 ERSLD-GTTFSPWQYYAVSDSECLSRY-NITPRRGPPTYRADDEVICTSYYSRLVPLEHG 195
ERS D G + ++Y+A +C + + NIT + + +++C S YS + P G
Sbjct: 144 ERSTDYGHNWKVFKYFA---KDCATSFPNITSGQA----QGVGDIVCDSKYSDIEPSTGG 196
Query: 196 EIHTSLINGRPSADD-LSPKLLEFTSARYIRLRLQRIRTLNADLMTLSHREPKELDPIVT 254
E+ +++ ++ SP + + + +R+ ++ TL L L R+ LD
Sbjct: 197 EVVLKVLDPSFEIENPYSPYIQDLVTLTNLRINFTKLHTLGDAL--LGRRQNDSLD---- 250
Query: 255 RRYYYSIKDISVGGMCICYGHASSC-PWDETTKKL---------QCQCEHNTCGESCNRC 304
+YYY++ ++ V G C C GHAS C P + + QC C+HNT G +C RC
Sbjct: 251 -KYYYALYEMIVRGSCFCNGHASECRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERC 309
Query: 305 CPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINC 364
+ PWRP N C +C+C++ + C++D + L+ GGVC +C
Sbjct: 310 KDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGGLS-------GGVCEDC 362
Query: 365 LQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLS-SVCIKDDLHSDLHNGKQ 423
NT G +C+ C +YR + + C PC CDP G++S +C+ HSD G
Sbjct: 363 QHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVS---HSDPALGSV 419
Query: 424 PGQCPCKEGYTGEKCDRCQ-----LGYKDYPTCVSCGCNPVGSASDEPC---TGPCVCKE 475
GQC CKE G KCD+C+ L D C C CNP+GS C TG C+C
Sbjct: 420 AGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLS 479
Query: 476 NVEGKACDRCKPGFYNLKEKNPRGCSECFC---FGVSDVCS 513
V G C+ C G++ L + GCS C C S+VCS
Sbjct: 480 YVTGAHCEECTVGYWGL-GNHLHGCSPCDCDIGGAYSNVCS 519
Score = 166 bits (419), Expect = 4e-40
Identities = 98/282 (34%), Positives = 140/282 (49%), Gaps = 37/282 (13%)
Query: 742 CECHGHAAECN---------------VHGVCIACAHNTTGVHCEQCLPGFYGEPSRGT-- 784
C C+GHA+EC VHG C+ C HNT G +CE+C F P R
Sbjct: 265 CFCNGHASECRPMQKMRGDVFSPPGMVHGQCV-CQHNTDGPNCERCKDFFQDAPWRPAAD 323
Query: 785 --PGDCQPCACPLTIASNNFSPTCHLNDG--DEVVCDWCAPGYSGAWCERCADGYYGNP- 839
C+ C+C + +F T +L G VC+ C G C+RC +Y +P
Sbjct: 324 LQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPL 383
Query: 840 -TVPGE-SCVPCDC------SGNVDPSEAGHC-DSVTGECLKCLGNTDGAHCERCADGFY 890
T+ +C+PC+C SG + S + SV G+CL C N +GA C++C Y
Sbjct: 384 KTISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCL-CKENVEGAKCDQCKPNHY 442
Query: 891 G-DAVTAKNCRACECHVKGS-HSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLDSG-HG 947
G A C+ C+C+ GS C ++TG C C VTG C++C GY+GL + HG
Sbjct: 443 GLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLGNHLHG 502
Query: 948 CRPCNCSVAGSVSDGCTDE-GQCHCVPGVAGKRCDRCAHGFY 988
C PC+C + G+ S+ C+ + GQC C P V G+ C A G++
Sbjct: 503 CSPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAPGYF 544
Score = 157 bits (396), Expect = 2e-37
Identities = 90/258 (34%), Positives = 125/258 (48%), Gaps = 47/258 (18%)
Query: 866 VTGECLKCLGNTDGAHCERCADGFYGDA-------VTAKNCRACECHVKGSHSAVCH--- 915
V G+C+ C NTDG +CERC D F+ DA + CR+C C+ SHS+ CH
Sbjct: 291 VHGQCV-CQHNTDGPNCERCKD-FFQDAPWRPAADLQDNACRSCSCN---SHSSRCHFDM 345
Query: 916 --------LETGLC-DCKPNVTGQQCDQCLHGYYG-----LDSGHGCRPCNCSVAGSVSD 961
L G+C DC+ N GQ CD+C +Y + + C PC C G++S
Sbjct: 346 TTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISG 405
Query: 962 G-CTDE---------GQCHCVPGVAGKRCDRCA---HGFYAYQDGSCTPCDCPHTQN--- 1005
G C GQC C V G +CD+C +G A C PCDC +
Sbjct: 406 GICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPF 465
Query: 1006 -TCDPETGECVCPPHTQGVKCEECEDGHWGYDAEV-GCQACNCSLVGSTHHRCDVVTGHC 1063
TCD +TG+C+C + G CEEC G+WG + GC C+C + G+ + C G C
Sbjct: 466 LTCDVDTGQCLCLSYVTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQC 525
Query: 1064 QCKSKFGGRACDQCSLGY 1081
+C+ GR+C + + GY
Sbjct: 526 ECRPHVTGRSCSEPAPGY 543
Score = 147 bits (371), Expect = 2e-34
Identities = 80/252 (31%), Positives = 113/252 (44%), Gaps = 22/252 (8%)
Query: 709 CECPQGYTGTSCESCLSGY----YRVDGILFGGICQPCECHGHAAECNVH---------- 754
C C G +CE C + +R L C+ C C+ H++ C+
Sbjct: 295 CVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGGL 354
Query: 755 --GVCIACAHNTTGVHCEQCLPGFYGEPSR--GTPGDCQPCACPLTIASNNFSPTCHLND 810
GVC C HNT G HC++C P FY +P + P C PC C + H +
Sbjct: 355 SGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHSDP 414
Query: 811 GDEVVCDWCA--PGYSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTG 868
V C GA C++C +YG C PCDC+ + CD TG
Sbjct: 415 ALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNP-LGSLPFLTCDVDTG 473
Query: 869 ECLKCLGNTDGAHCERCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNVT 928
+CL CL GAHCE C G++G C C+C + G++S VC + G C+C+P+VT
Sbjct: 474 QCL-CLSYVTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQCECRPHVT 532
Query: 929 GQQCDQCLHGYY 940
G+ C + GY+
Sbjct: 533 GRSCSEPAPGYF 544
Score = 137 bits (346), Expect = 1e-31
Identities = 186/873 (21%), Positives = 328/873 (37%), Gaps = 174/873 (19%)
Query: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPN-----T 1416
C C G G C +C+ G++ PR APC PC+CNN+ D DP T
Sbjct: 938 CNCLQGYTGTQCGECSTGFYGN---------PRISGAPCQPCACNNNIDVTDPESCSRVT 988
Query: 1417 GKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHS-------PPASFSPTC--- 1466
G+CL C NT G +C +C G+YG C C+C S PP + C
Sbjct: 989 GECLRCLHNTQGANCQLCKPGHYGSALNQT--CRRCSCHASGVSPMECPPGGGACLCDPV 1046
Query: 1467 ------------------------VLEGDHDFRCDA------------------CLLGYE 1484
++ G CD C LGY
Sbjct: 1047 TGACPCLPNVTGLACDRCADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYG 1106
Query: 1485 GKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDECEP 1544
GK C C +YYG+P G C CDCN G+ CD +G C CR G SG RCD C
Sbjct: 1107 GKRCSECQENYYGDPP---GRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRCAR 1163
Query: 1545 RHILMETDCVSCDDECVGVLLNDLDEIGDAV-----LSLNLTG---IIPVPYGILSNLEN 1596
H C+ C C + + + AV L+ N+ +PV +L
Sbjct: 1164 GHSQEFPTCLQC-HLCFDQWDHTISSLSKAVQGLMRLAANMEDKRETLPVCEADFKDLRG 1222
Query: 1597 TTKYLQESLLKENMQKDLGKIKLEGVAEETDNLQKKLTRMLASTQKVNRATERIFKESQD 1656
+ E +LK + K V + D++++++ ++N + ++ E QD
Sbjct: 1223 NVSEI-ERILKHPV---FPSGKFLKVKDYHDSVRRQI-------MQLNEQLKAVY-EFQD 1270
Query: 1657 LAIAIERLQMSITEIMEKTTLNQTLDEDFLLPNSTLQNMQQNGTSLLEIMQIRDFTQLHQ 1716
L IER + ++E L + +D + N+++ + +N I +
Sbjct: 1271 LKDTIERAKNEADLLLE--DLQEEIDLQSSVLNASIADSSENIKKYYHISSSAEKKINET 1328
Query: 1717 NATLELKA--AEDLLSQIQENYQKPLEELEVLKEAASHVLSKHNNEL------------- 1761
++T+ A DLL+ + K LE LK+ + N ++
Sbjct: 1329 SSTINTSANTRNDLLTILDTLTSKGNLSLERLKQIKIPDIQILNEKVCGDPGNVPCVPLP 1388
Query: 1762 --------------------KAAEALVREAEAKMQESNHLLLMVNANLREFSDKKLHVQE 1801
+ L A K QE+ ++ ++ +R ++ + E
Sbjct: 1389 CGGALCTGRKGHRKCRGPGCHGSLTLSTNALQKAQEAKSIIRNLDKQVRGLKNQIESISE 1448
Query: 1802 EQNLTSELIVQGRGLIDAAAAQTDAVQDALEHLEDHQDKLLLWS-------AKIRHHIDD 1854
+ ++ +Q R + Q+D+ ++ + LL K+ + + D
Sbjct: 1449 QAEVSKNNALQLREKLGNIRNQSDSEEENINLFIKKVKNFLLEENVPPEDIEKVANGVLD 1508
Query: 1855 LVMHMSQRNAVDLVYR-------AEDHAAEFQRLADVLYSGLENIRNVSLNATSAAYVHY 1907
+ + + +N D + + ED+ + RL + G + + + A AA +
Sbjct: 1509 IHLPIPSQNLTDELVKIQKHMQLCEDYRTDENRLNEEA-DGAQKLLVKAKAAEKAANILL 1567
Query: 1908 NIQSLIEESEELARDAHRTVTETSLLSESLVSNGKAAVQ--RSSRFLKEGNNLSRKLPGI 1965
N+ + + ++ R + + L+ ++ K +Q +R +K L+++ G+
Sbjct: 1568 NLDKTLNQLQQAQITQGRANSTITQLTANITKIKKNVLQAENQTREMKSELELAKQRSGL 1627
Query: 1966 ALELSELRNKTNRFQENAVEITRQTNESLLILRAIPKGIRDKGAKTKELATSASQSAVST 2025
LS L+ K R Q++AV Q + G+ KE Q A+
Sbjct: 1628 EDGLSLLQTKLQRHQDHAVNAKVQAESAQ----------HQAGSLEKEFVELKKQYAILQ 1677
Query: 2026 LR-DVAGLSQELLNTSASLSRVNTTLRETHQLLQDSTMATLL----AGRKVKDVEIQANL 2080
+ GL++E +L +V L++ + L T A + RK++D+ +
Sbjct: 1678 RKTSTTGLTKE------TLGKVK-QLKDAAEKLAGDTEAKIRRITDLERKIQDLNLSRQA 1730
Query: 2081 LFDRLKPLKMLEENLSRNLSEIKLLISQARKQA 2113
D+ L++LE+ + +EI + Q +K A
Sbjct: 1731 KADQ---LRILEDQVVAIKNEI---VEQEKKYA 1757
Score = 135 bits (341), Expect = 5e-31
Identities = 92/289 (31%), Positives = 117/289 (40%), Gaps = 48/289 (16%)
Query: 1343 GRKAEKLHPEEEVAS----LLENCVCPPGTVGFSCQDCAPGYH----------------- 1381
G A K HP+ V S L C C P VG C C+ G +
Sbjct: 765 GAVACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHPCHCHPQGS 824
Query: 1382 --------RGKLPAGSD----RGPRPLVA-----PCVPCSCNNHSDTCDPNTGKCLNCGD 1424
G+ P + R R L C PC CN ++ CDP TG C NCG
Sbjct: 825 KDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFPSCHPCPCNRFAELCDPETGSCFNCGG 884
Query: 1425 NTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPAS--FSPTCVLE-GDHDFRCDACLL 1481
T G +C+ C GYYG S C C CP P ++ F+ +C D C+ CL
Sbjct: 885 FTTGRNCERCIDGYYGN-PSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICN-CLQ 942
Query: 1482 GYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHG--DCDRTSGQCV-CRLGASGLR 1538
GY G C CS+ +YGNP+ G CQ C CN + V C R +G+C+ C G
Sbjct: 943 GYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGAN 1002
Query: 1539 CDECEPRHI--LMETDCVSCDDECVGVLLNDLDEIGDAVLSLNLTGIIP 1585
C C+P H + C C GV + G A L +TG P
Sbjct: 1003 CQLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACP 1051
Score = 129 bits (324), Expect = 4e-29
Identities = 80/286 (27%), Positives = 120/286 (41%), Gaps = 55/286 (19%)
Query: 898 NCRACECH----VKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLD-------SGH 946
N A EC ++G + + G C C+ N G C++C + +
Sbjct: 268 NGHASECRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDN 327
Query: 947 GCRPCNCSVAGS---------VSDGCTDEGQCH-CVPGVAGKRCDRCAHGFYA------Y 990
CR C+C+ S ++ G G C C G+ CDRC FY
Sbjct: 328 ACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTIS 387
Query: 991 QDGSCTPCDCP------------HTQNTCDPETGECVCPPHTQGVKCEECEDGHWGYDAE 1038
+C PC+C H+ G+C+C + +G KC++C+ H+G A
Sbjct: 388 DPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSAT 447
Query: 1039 --VGCQACNCSLVGSTHH-RCDVVTGHCQCKSKFGGRACDQCSLGY----RDFPDCVPCD 1091
+GCQ C+C+ +GS CDV TG C C S G C++C++GY C PCD
Sbjct: 448 DPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLGNHLHGCSPCD 507
Query: 1092 CDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTF 1137
CD+ G + C+ + G C C+ +V G C+E G F
Sbjct: 508 CDIGGAYSNVCS---------PKNGQCECRPHVTGRSCSEPAPGYF 544
Score = 100 bits (250), Expect = 2e-20
Identities = 66/199 (33%), Positives = 84/199 (42%), Gaps = 22/199 (11%)
Query: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTC--DPNT--- 1416
CVC T G +C+ C + +D C CSCN+HS C D T
Sbjct: 295 CVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNA----CRSCSCNSHSSRCHFDMTTYLA 350
Query: 1417 ------GKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCA-CPHSPPASFSP-TCVL 1468
G C +C NT G HCD C +Y + SD C C P + S CV
Sbjct: 351 SGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVS 410
Query: 1469 EGDHDFRCDA----CLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSV-HGDCDR 1523
D A C EG C++C ++YG T CQ CDCNP GS+ CD
Sbjct: 411 HSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDV 470
Query: 1524 TSGQCVCRLGASGLRCDEC 1542
+GQC+C +G C+EC
Sbjct: 471 DTGQCLCLSYVTGAHCEEC 489
Score = 97.1 bits (240), Expect = 2e-19
Identities = 64/174 (36%), Positives = 88/174 (50%), Gaps = 30/174 (17%)
Query: 1012 GECVCPPHTQGVKCEEC----EDGHWGYDAEV---GCQACNCSLVGSTHHRCDVVT---- 1060
G+CVC +T G CE C +D W A++ C++C+C+ S H D+ T
Sbjct: 293 GQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCH-FDMTTYLAS 351
Query: 1061 -----GHCQ-CKSKFGGRACDQCS-LGYRD----FPD---CVPCDCDLRGT-SGDAC-NL 1104
G C+ C+ G+ CD+C L YRD D C+PC+CD GT SG C +
Sbjct: 352 GGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSH 411
Query: 1105 EQGLCGCVEETGACPCKENVFGPQCNECREGTFALRADNPLGCSPCFCSGLSHL 1158
G V G C CKENV G +C++C+ + L A +PLGC PC C+ L L
Sbjct: 412 SDPALGSV--AGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSL 463
Score = 87.0 bits (214), Expect = 3e-16
Identities = 59/200 (29%), Positives = 85/200 (42%), Gaps = 39/200 (19%)
Query: 1403 CSCNNHSDTCDPNT--------------GKCLNCGDNTAGDHCDVCTSGYYGKVTGSASD 1448
C CN H+ C P G+C+ C NT G +C+ C + A+D
Sbjct: 265 CFCNGHASECRPMQKMRGDVFSPPGMVHGQCV-CQHNTDGPNCERCKDFFQDAPWRPAAD 323
Query: 1449 -----CALCAC-PHSPPASFSPTCVLE--GDHDFRCDACLLGYEGKHCERCSSSYYGNPQ 1500
C C+C HS F T L G C+ C EG+HC+RC +Y +P
Sbjct: 324 LQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPL 383
Query: 1501 ---TPGGSCQKCDCNPHGSVHGDC---------DRTSGQCVCRLGASGLRCDECEPRHI- 1547
+ +C C+C+P G++ G +GQC+C+ G +CD+C+P H
Sbjct: 384 KTISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYG 443
Query: 1548 LMETD---CVSCDDECVGVL 1564
L TD C CD +G L
Sbjct: 444 LSATDPLGCQPCDCNPLGSL 463
Score = 86.7 bits (213), Expect = 3e-16
Identities = 61/193 (31%), Positives = 76/193 (39%), Gaps = 25/193 (12%)
Query: 1364 CPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCN-----------NHSDTC 1412
C T G C C P ++R L SD C+PC C+ +HSD
Sbjct: 362 CQHNTEGQHCDRCRPLFYRDPLKTISDP------YACIPCECDPDGTISGGICVSHSDPA 415
Query: 1413 DPNT-GKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGD 1471
+ G+CL C +N G CD C +YG C C C F TC D
Sbjct: 416 LGSVAGQCL-CKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFL-TC----D 469
Query: 1472 HDFRCDACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCR 1531
D CL G HCE C+ Y+G G C CDC+ G+ C +GQC CR
Sbjct: 470 VDTGQCLCLSYVTGAHCEECTVGYWGLGNHLHG-CSPCDCDIGGAYSNVCSPKNGQCECR 528
Query: 1532 LGASGLRCDECEP 1544
+G C E P
Sbjct: 529 PHVTGRSCSEPAP 541
Score = 85.1 bits (209), Expect = 1e-15
Identities = 75/261 (28%), Positives = 91/261 (34%), Gaps = 53/261 (20%)
Query: 944 SGHG--CRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCDRCAHGFYA--------YQDG 993
+GH CRP S GQC C G C+RC F QD
Sbjct: 268 NGHASECRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDN 327
Query: 994 SCTPCDCPHTQNTC--DPET---------GECV-CPPHTQGVKCEECE-----DGHWGYD 1036
+C C C + C D T G C C +T+G C+ C D
Sbjct: 328 ACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTIS 387
Query: 1037 AEVGCQACNCSLVGSTHHRCDV---------VTGHCQCKSKFGGRACDQCS-----LGYR 1082
C C C G+ V V G C CK G CDQC L
Sbjct: 388 DPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSAT 447
Query: 1083 DFPDCVPCDCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFALRAD 1142
D C PCDC+ G+ C +TG C C V G C EC G + L +
Sbjct: 448 DPLGCQPCDCNPLGSLP--------FLTCDVDTGQCLCLSYVTGAHCEECTVGYWGL-GN 498
Query: 1143 NPLGCSPCFC---SGLSHLCS 1160
+ GCSPC C S++CS
Sbjct: 499 HLHGCSPCDCDIGGAYSNVCS 519
Score = 79.3 bits (194), Expect = 5e-14
Identities = 50/191 (26%), Positives = 76/191 (39%), Gaps = 56/191 (29%)
Query: 267 GGMCICYGHASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEA 326
GG C+C +CP C N G +C+RC GY W + G C++
Sbjct: 1038 GGACLCDPVTGACP-----------CLPNVTGLACDRCADGY----W---NLVPGRGCQS 1079
Query: 327 CNCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKV 386
C+C + + + + Q C G C C + Y
Sbjct: 1080 CDCDPRTSQSSHCDQLTGQ----------------CPCKLGYGGKRCSECQENY------ 1117
Query: 387 SPYEDEP--CRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLG 444
Y D P C PC+C+ G+ +C D G C C+EG +G++CDRC G
Sbjct: 1118 --YGDPPGRCIPCDCNRAGTQKPICDPD-----------TGMCRCREGVSGQRCDRCARG 1164
Query: 445 Y-KDYPTCVSC 454
+ +++PTC+ C
Sbjct: 1165 HSQEFPTCLQC 1175
Score = 62.4 bits (150), Expect = 7e-09
Identities = 43/154 (27%), Positives = 63/154 (40%), Gaps = 21/154 (13%)
Query: 1350 HPEEEVASLLENCVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHS 1409
H + + S+ C+C G C C P ++ L A G C PC CN
Sbjct: 411 HSDPALGSVAGQCLCKENVEGAKCDQCKPNHY--GLSATDPLG-------CQPCDCNPLG 461
Query: 1410 D----TCDPNTGKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPT 1465
TCD +TG+CL C G HC+ CT GY+G + C+ C C ++S
Sbjct: 462 SLPFLTCDVDTGQCL-CLSYVTGAHCEECTVGYWG-LGNHLHGCSPCDCDIG--GAYSNV 517
Query: 1466 CVLEGDHDFRCDACLLGYEGKHCERCSSSYYGNP 1499
C + +C+ C G+ C + Y+ P
Sbjct: 518 C---SPKNGQCE-CRPHVTGRSCSEPAPGYFFAP 547
Score = 50.8 bits (120), Expect = 2e-05
Identities = 30/98 (30%), Positives = 39/98 (39%), Gaps = 17/98 (17%)
Query: 1358 LLENCVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCN---NHSDTCDP 1414
L C C G G C +C Y+ G P C+PC CN CDP
Sbjct: 1095 LTGQCPCKLGYGGKRCSECQENYY----------GDPP--GRCIPCDCNRAGTQKPICDP 1142
Query: 1415 NTGKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALC 1452
+TG C C + +G CD C G + + + C LC
Sbjct: 1143 DTGMC-RCREGVSGQRCDRCARG-HSQEFPTCLQCHLC 1178
>gi|119703755 laminin, beta 2 precursor [Homo sapiens]
Length = 1798
Score = 284 bits (727), Expect = 8e-76
Identities = 134/351 (38%), Positives = 186/351 (52%), Gaps = 22/351 (6%)
Query: 709 CECPQGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAAECNVH-GVCIACAHNTTGV 767
C C G G C+ C G + C+PC C+GHA ECN H G C+ C +T G
Sbjct: 850 CLCRTGAFGLRCDRCQRGQWGFPS------CRPCVCNGHADECNTHTGACLGCRDHTGGE 903
Query: 768 HCEQCLPGFYGEPSRGTPGDCQPCACPLTIASN-NFSPTCHLNDGDEVVCDWCAPGYSGA 826
HCE+C+ GF+G+P G C+PC CP S +F+ +CH ++ + + C GY+G
Sbjct: 904 HCERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGL 963
Query: 827 WCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCA 886
CE CA G++G+P+ PG C C+CSGN+DP + CD TG+CL+CL +T+G HC C
Sbjct: 964 RCEACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCK 1023
Query: 887 DGFYGDAVTAKNCRACECHVKGSHSA------VCHLE--TGLCDCKPNVTGQQCDQCLHG 938
GF+G A ++C C C++ G++ CH + +G C C PNV G CD+C
Sbjct: 1024 PGFHGQA-ARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPN 1082
Query: 939 YYGLDSGHGCRPCNCSVAGSVSDGCTD-EGQCHCVPGVAGKRCDRCAHGFYAYQDGSCTP 997
++ L SGHGC+PC C + + C + GQCHC G G+ C C + C
Sbjct: 1083 FWNLTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQCHA 1142
Query: 998 CDCPH---TQNTCDPETGECVCPPHTQGVKCEECEDGHWG-YDAEVGCQAC 1044
CDC C TG C C P GV+C++C G G + A C AC
Sbjct: 1143 CDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGFSGIFPACHPCHAC 1193
Score = 239 bits (611), Expect = 2e-62
Identities = 170/542 (31%), Positives = 243/542 (44%), Gaps = 72/542 (13%)
Query: 1 MRGGVLLVLLLCVAAQ--------CRQRGLFPAILNLASNA--HISTNATCGEKGPEMFC 50
+R G+LL +L AQ C + +PA +L ++ ++TCG GP+ +C
Sbjct: 18 LRLGLLLSVLAATLAQAPAPDVPGCSRGSCYPATGDLLVGRADRLTASSTCGLNGPQPYC 77
Query: 51 KLVEHVPGRPVRNPQCRICDGNSANPRERHPISHAIDGTNN---------WWQSPSIQNG 101
+V H+ +C +CD +P SH I WWQS +NG
Sbjct: 78 -IVSHLQDEK----KCFLCDSRRPFSARDNPHSHRIQNVVTSFAPQRRAAWWQS---ENG 129
Query: 102 REYHWVTITLDLRQVFQVAYVIIKAANAPRPGNWILERSLD-GTTFSPWQYYAVSDSECL 160
VTI LDL F ++I+ RP ++ERS D G T+ ++Y++ +C
Sbjct: 130 IPA--VTIQLDLEAEFHFTHLIMTFKTF-RPAAMLVERSADFGRTWHVYRYFSY---DCG 183
Query: 161 SRYNITPRRGPPTYRADDEVICTSYYSRLVPLEHGE-IHTSLINGRPSADDLSPKLLEFT 219
+ + P P R D+V+C S YS + P GE I+ L P D S ++
Sbjct: 184 ADFPGVPLAPP---RHWDDVVCESRYSEIEPSTEGEVIYRVLDPAIPIPDPYSSRIQNLL 240
Query: 220 SARYIRLRLQRIRTLNADLMTLSHREPKELDPIVTRRYYYSIKDISVGGMCICYGHASSC 279
+R+ L R+ TL +L+ RE +E +YYY++ ++ V G C CYGHAS C
Sbjct: 241 KITNLRVNLTRLHTLGDNLLD-PRREIRE-------KYYYALYELVVRGNCFCYGHASEC 292
Query: 280 P-------WDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNK 332
E C C+HNT G +C +C Y PWRP + C C CH
Sbjct: 293 APAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGH 352
Query: 333 AKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDE 392
C++D +V +++ GGVC C NT G +CE C +YR +
Sbjct: 353 THSCHFDMAVYLASGNVS-------GGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPA 405
Query: 393 PCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGY-----KD 447
CR C+CDP+GS + D H D G GQC CKE G +C +C+ G+ D
Sbjct: 406 VCRSCDCDPMGSQDGG--RCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISD 463
Query: 448 YPTCVSCGCNP----VGSASDEPCTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSEC 503
C C CN GS +P +G C CK V G+ CDRC PG + L + GC C
Sbjct: 464 RLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSH-DLLGCRPC 522
Query: 504 FC 505
C
Sbjct: 523 DC 524
Score = 231 bits (588), Expect = 1e-59
Identities = 149/465 (32%), Positives = 199/465 (42%), Gaps = 72/465 (15%)
Query: 721 ESCLSGYYRVDGILFGGICQPCECHGH---AAECNVHGVCIACAHNTTGVHCEQCLPGFY 777
E+C + +++ G PC+C+ ++ECN HG C G C+ C PG+Y
Sbjct: 763 EACAPLLISLSTLIYNGAL-PCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYY 821
Query: 778 GEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYG 837
G G CQ C C A S C G + C G G C+RC G +G
Sbjct: 822 GFGPTG----CQACQCSHEGA---LSSLCEKTSGQCL----CRTGAFGLRCDRCQRGQWG 870
Query: 838 NPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCADGFYGDAVT-- 895
P SC PC C+G+ D C++ TG CL C +T G HCERC GF+GD
Sbjct: 871 FP-----SCRPCVCNGHAD-----ECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPY 920
Query: 896 AKNCRACEC-HVKGSH---SAVCHLETG----LCDCKPNVTGQQCDQCLHGYYGLDSGHG 947
CR C C GS + CH + +C C+ TG +C+ C G++G S G
Sbjct: 921 GGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPG 980
Query: 948 --CRPCNCSVAGSVS----DGCTDE-GQC-HCVPGVAGKRCDRCAHGFYAYQDG-SCTPC 998
C+ C CS G++ D C GQC C+ G C C GF+ SC C
Sbjct: 981 GRCQLCECS--GNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSCHRC 1038
Query: 999 DC-----------PHTQNTCDPETGECVCPPHTQGVKCEECEDGHWGYDAEVGCQACNCS 1047
C Q CDP +G+C C P+ QG C+ C W + GCQ C C
Sbjct: 1039 TCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHGCQPCACH 1098
Query: 1048 LVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGYRDFP--DCVPCDCDLRGTSGDACNLE 1105
+ C+ TG C C++ FGGR C +C + P C CDCD RG C+
Sbjct: 1099 PSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQCHACDCDSRGIDTPQCH-- 1156
Query: 1106 QGLCGCVEETGACPCKENVFGPQCNECREGTFALRADNPLGCSPC 1150
TG C C+ V G +C++C G + C PC
Sbjct: 1157 -------RFTGHCSCRPGVSGVRCDQCARGFSGIFP----ACHPC 1190
Score = 182 bits (461), Expect = 6e-45
Identities = 192/743 (25%), Positives = 276/743 (37%), Gaps = 142/743 (19%)
Query: 890 YGDAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLD------ 943
YG A H +G + G C CK N G C+QC Y L
Sbjct: 286 YGHASECAPAPGAPAHAEG-------MVHGACICKHNTRGLNCEQCQDFYRDLPWRPAED 338
Query: 944 -SGHGCRPCNC---------SVAGSVSDGCTDEGQCH-CVPGVAGKRCDRCAHGFYA--- 989
H CR C C +A ++ G G C C AG+ C+ C FY
Sbjct: 339 GHSHACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPT 398
Query: 990 ---YQDGSCTPCDCP----HTQNTCDPE--------TGECVCPPHTQGVKCEECEDGHWG 1034
C CDC CD +G+C C H G +C++C DG +G
Sbjct: 399 KDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFG 458
Query: 1035 YDAE--VGCQACNCSLVGSTHHR--CDVVTGHCQCKSKFGGRACDQCSLGY----RDFPD 1086
+GC+ C C+ G+ CD +G C CK GR CD+C G+ D
Sbjct: 459 LSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLG 518
Query: 1087 CVPCDCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFALRADNPLG 1146
C PCDCD+ G C+ E TG C C++++ G +C + + G F D+ +
Sbjct: 519 CRPCDCDVGGALDPQCD---------EGTGQCHCRQHMVGRRCEQVQPGYFRPFLDHLIW 569
Query: 1147 CSPCFCSGLSHLCSELEDYVRTPVTLGSDQPLLRVVSQSNLRGTTEGVYYQAPDFLLDAA 1206
+ + + L TP GS +R+ L V +A D+ L
Sbjct: 570 EAEDTRGQVLDVVERLVTPGETPSWTGSG--FVRLQEGQTLEFLVASV-PKAMDYDL--- 623
Query: 1207 TVRQHIRAEPFYWRLPQQFQGDQLMAYGGKLKYSVAFYSLDGVGTSNFEPQVLIKGGRIR 1266
+R EP ++P+Q+ +L+ + V +SL G + P+ G ++
Sbjct: 624 ----LLRLEP---QVPEQWAELELIV---QRPGPVPAHSLCG----HLVPKDDRIQGTLQ 669
Query: 1267 KQVIYMDAPAPENGVRQEQEVAMRENFWKYFNSVSEKPVTREDFMSVLSD----IEYILI 1322
Y+ P P V E ++ + + S +P T +L D + +L+
Sbjct: 670 PHARYLIFPNP---VCLEPGISYKLHLKLVRTGGSAQPETPYSGPGLLIDSLVLLPRVLV 726
Query: 1323 KASYGQGLQQSRISDISME------VGRKAEKLHPEEEVASLLEN-----------CVC- 1364
+ G + + E G K P E A LL + C C
Sbjct: 727 LEMFSGGDAAALERQATFERYQCHEEGLVPSKTSPSEACAPLLISLSTLIYNGALPCQCN 786
Query: 1365 PPGTVGFSCQD------CAPGY--HRGKLPAGSDRGPRPLVAPCVPCSCNNH---SDTCD 1413
P G++ C C PG R L A G P C C C++ S C+
Sbjct: 787 PQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGP--TGCQACQCSHEGALSSLCE 844
Query: 1414 PNTGKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGDHD 1473
+G+CL C G CD C G +G C C C + C H
Sbjct: 845 KTSGQCL-CRTGAFGLRCDRCQRGQWG-----FPSCRPCVC-----NGHADEC---NTHT 890
Query: 1474 FRCDACLLGYEGKHCERCSSSYYGNPQTP-GGSCQKCDCNPHG---------SVHGDCDR 1523
C C G+HCERC + ++G+P+ P GG C+ C C P G S H D
Sbjct: 891 GACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPC-PEGPGSQRHFATSCHQDEYS 949
Query: 1524 TSGQCVCRLGASGLRCDECEPRH 1546
C CR G +GLRC+ C P H
Sbjct: 950 QQIVCHCRAGYTGLRCEACAPGH 972
Score = 174 bits (440), Expect = 2e-42
Identities = 100/281 (35%), Positives = 144/281 (51%), Gaps = 37/281 (13%)
Query: 742 CECHGHAAEC------------NVHGVCIACAHNTTGVHCEQCLPGFYGEPSR----GTP 785
C C+GHA+EC VHG CI C HNT G++CEQC + P R G
Sbjct: 283 CFCYGHASECAPAPGAPAHAEGMVHGACI-CKHNTRGLNCEQCQDFYRDLPWRPAEDGHS 341
Query: 786 GDCQPCACPLTIASNNFSPTCHLNDGDEV--VCDWCAPGYSGAWCERCADGYYGNPTVPG 843
C+ C C S +F +L G+ VCD C +G CE C +Y +PT
Sbjct: 342 HACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDL 401
Query: 844 ES---CVPCDCSGNVDPSEAGHCDS--------VTGECLKCLGNTDGAHCERCADGFYGD 892
C CDC + + G CDS V+G+C +C + G C++C DGF+G
Sbjct: 402 RDPAVCRSCDCD-PMGSQDGGRCDSHDDPALGLVSGQC-RCKEHVVGTRCQQCRDGFFGL 459
Query: 893 AVTAK-NCRACECHVKGS--HSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLDSG-HGC 948
+++ + CR C+C+ +G+ S C +G C CK VTG+ CD+CL G++GL GC
Sbjct: 460 SISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLGC 519
Query: 949 RPCNCSVAGSVSDGCTD-EGQCHCVPGVAGKRCDRCAHGFY 988
RPC+C V G++ C + GQCHC + G+RC++ G++
Sbjct: 520 RPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYF 560
Score = 144 bits (364), Expect = 1e-33
Identities = 93/288 (32%), Positives = 120/288 (41%), Gaps = 55/288 (19%)
Query: 849 CDCSGNVD-----PSEAGHCDS-VTGECLKCLGNTDGAHCERCADGFYGDAVT------- 895
C C G+ P H + V G C+ C NT G +CE+C D FY D
Sbjct: 283 CFCYGHASECAPAPGAPAHAEGMVHGACI-CKHNTRGLNCEQCQD-FYRDLPWRPAEDGH 340
Query: 896 AKNCRACECHVKGSHSAVCHLET-----------GLCD-CKPNVTGQQCDQCLHGYY--- 940
+ CR CECH H+ CH + G+CD C+ N G+ C+ C +Y
Sbjct: 341 SHACRKCECH---GHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDP 397
Query: 941 --GLDSGHGCRPCNCSVAGSVSDGCTDE----------GQCHCVPGVAGKRCDRCAHGFY 988
L CR C+C GS G D GQC C V G RC +C GF+
Sbjct: 398 TKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFF 457
Query: 989 AYQDGS---CTPCDCPHT-----QNTCDPETGECVCPPHTQGVKCEECEDGHWGYDAEV- 1039
C C C CDP +G C C G C+ C GHWG ++
Sbjct: 458 GLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLL 517
Query: 1040 GCQACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGY-RDFPD 1086
GC+ C+C + G+ +CD TG C C+ GR C+Q GY R F D
Sbjct: 518 GCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYFRPFLD 565
Score = 132 bits (331), Expect = 7e-30
Identities = 76/254 (29%), Positives = 107/254 (42%), Gaps = 25/254 (9%)
Query: 709 CECPQGYTGTSCESCLSGYYRV------DGILFGGICQPCECHGHAAECNVH-------- 754
C C G +CE C Y + DG C+ CECHGH C+
Sbjct: 310 CICKHNTRGLNCEQCQDFYRDLPWRPAEDG--HSHACRKCECHGHTHSCHFDMAVYLASG 367
Query: 755 ----GVCIACAHNTTGVHCEQCLPGFYGEPSRGT--PGDCQPCACPLTIASNNFSPTCHL 808
GVC C HNT G HCE C P FY +P++ P C+ C C + + H
Sbjct: 368 NVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHD 427
Query: 809 NDGDEVVCDWCA--PGYSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSV 866
+ +V C G C++C DG++G C C C+ + CD
Sbjct: 428 DPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPN 487
Query: 867 TGECLKCLGNTDGAHCERCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPN 926
+G C C G C+RC G +G + CR C+C V G+ C TG C C+ +
Sbjct: 488 SGSCY-CKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQH 546
Query: 927 VTGQQCDQCLHGYY 940
+ G++C+Q GY+
Sbjct: 547 MVGRRCEQVQPGYF 560
Score = 126 bits (317), Expect = 3e-28
Identities = 70/225 (31%), Positives = 99/225 (44%), Gaps = 44/225 (19%)
Query: 1362 CVCPPGTVGFSCQDCAPGY--------------HRGKLPAGSDRGPRPLVA--------- 1398
C+C PG VG C CAPGY H G L + ++ +
Sbjct: 802 CLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSHEGALSSLCEKTSGQCLCRTGAFGLRC 861
Query: 1399 -----------PCVPCSCNNHSDTCDPNTGKCLNCGDNTAGDHCDVCTSGYYGKV-TGSA 1446
C PC CN H+D C+ +TG CL C D+T G+HC+ C +G++G
Sbjct: 862 DRCQRGQWGFPSCRPCVCNGHADECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYG 921
Query: 1447 SDCALCACPHSPPAS--FSPTCVLEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQTPGG 1504
C C CP P + F+ +C + C GY G CE C+ ++G+P PGG
Sbjct: 922 GQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGG 981
Query: 1505 SCQKCDCNPHGSVH----GDCDRTSGQCV-CRLGASGLRCDECEP 1544
CQ C+C+ G++ CD +GQC+ C G C C+P
Sbjct: 982 RCQLCECS--GNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKP 1024
Score = 112 bits (280), Expect = 6e-24
Identities = 110/495 (22%), Positives = 192/495 (38%), Gaps = 80/495 (16%)
Query: 1346 AEKLHPEEEVASLLENCVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSC 1405
A H +E ++ C C G G C+ CAPG+ G C C C
Sbjct: 940 ATSCHQDEYSQQIV--CHCRAGYTGLRCEACAPGHFGDPSRPGGR---------CQLCEC 988
Query: 1406 NNH-----SDTCDPNTGKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCAC------ 1454
+ + D CDP+TG+CL C +T G HC C G++G+ + C C C
Sbjct: 989 SGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQ--AARQSCHRCTCNLLGTN 1046
Query: 1455 PHSPPASFSPTCVLEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPH 1514
P P+ C D CL +G C+RC+ +++ T G CQ C C+P
Sbjct: 1047 PQQCPSPDQCHC----DPSSGQCPCLPNVQGPSCDRCAPNFWN--LTSGHGCQPCACHPS 1100
Query: 1515 GSVHGDCDRTSGQCVCRLGASGLRCDECEPRHI-LMETDCVSCDDECVGV---------- 1563
+ C+ +GQC CR G G C EC+ H C +CD + G+
Sbjct: 1101 RARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQCHACDCDSRGIDTPQCHRFTG 1160
Query: 1564 ---LLNDLDEIGDAVLSLNLTGIIPVPYGILSNLENTTKYLQESLLK----ENMQKDLGK 1616
+ + + +GI P + + + + +Q+ + E ++L +
Sbjct: 1161 HCSCRPGVSGVRCDQCARGFSGIFPACHPCHACFGDWDRVVQDLAARTQRLEQRAQELQQ 1220
Query: 1617 IKLEGVAEETD-NLQKKL----------TRMLASTQKVNRATERIFKESQDLAIAIERLQ 1665
+ G E + ++Q+KL AST ++ ATE + +E + + +L+
Sbjct: 1221 TGVLGAFESSFWHMQEKLGIVQGIVGARNTSAASTAQLVEATEELRREIGEATEHLTQLE 1280
Query: 1666 MSITEIM-EKTTLNQT---LDEDFLLPNSTLQNMQQNGTSLLEIMQIRDFTQLH------ 1715
+T++ E N L+ D L N TL+ + Q+ L++++ +F +
Sbjct: 1281 ADLTDVQDENFNANHALSGLERDRLALNLTLRQLDQH----LDLLKHSNFLGAYDSIRHA 1336
Query: 1716 --QNATLELKAAEDLLSQIQENYQKPLEELEVLKEAASHVLSKHNNELKAAEALVREAEA 1773
Q+A E +A L+ P+ + ++ + + + A
Sbjct: 1337 HSQSAEAERRANTSALA-----VPSPVSNSASARHRTEALMDAQKEDFNSKHMANQRALG 1391
Query: 1774 KMQESNHLLLMVNAN 1788
K+ H L + + N
Sbjct: 1392 KLSAHTHTLSLTDIN 1406
Score = 99.4 bits (246), Expect = 5e-20
Identities = 75/261 (28%), Positives = 98/261 (37%), Gaps = 65/261 (24%)
Query: 270 CICYGHASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNC 329
C+C GHA C T C +T GE C RC G+H P P G C C C
Sbjct: 877 CVCNGHADEC---NTHTGACLGCRDHTGGEHCERCIAGFHGDPRLP----YGGQCRPCPC 929
Query: 330 -------HNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYY- 381
+ A C+ DE + + +C G+ CE C G++
Sbjct: 930 PEGPGSQRHFATSCHQDEYSQQ---------------IVCHCRAGYTGLRCEACAPGHFG 974
Query: 382 ---RPHKVSPYED-----EPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGY 433
RP + +P P CDP C LH+ + P CK G+
Sbjct: 975 DPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRC--------LHHTEGPHCAHCKPGF 1026
Query: 434 TGE----KCDRCQLGYKDYPTCVSCGCNPVGSASDEPC-----TGPCVCKENVEGKACDR 484
G+ C RC TC G NP S + C +G C C NV+G +CDR
Sbjct: 1027 HGQAARQSCHRC--------TCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDR 1078
Query: 485 CKPGFYNLKEKNPRGCSECFC 505
C P F+NL + GC C C
Sbjct: 1079 CAPNFWNL--TSGHGCQPCAC 1097
Score = 97.8 bits (242), Expect = 1e-19
Identities = 66/240 (27%), Positives = 92/240 (38%), Gaps = 44/240 (18%)
Query: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTC--------- 1412
C+C T G +C+ C Y D C C C+ H+ +C
Sbjct: 310 CICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHA----CRKCECHGHTHSCHFDMAVYLA 365
Query: 1413 --DPNTGKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALC-ACPHSPPASFSPTCVLE 1469
+ + G C C NTAG HC++C +Y T D A+C +C P S
Sbjct: 366 SGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGS-------- 417
Query: 1470 GDHDFRCDA--------------CLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHG 1515
RCD+ C G C++C ++G + C++C CN G
Sbjct: 418 -QDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARG 476
Query: 1516 SVHGD--CDRTSGQCVCRLGASGLRCDECEPRHILMETD---CVSCDDECVGVLLNDLDE 1570
+V G CD SG C C+ +G CD C P H + D C CD + G L DE
Sbjct: 477 TVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDE 536
Score = 87.8 bits (216), Expect = 1e-16
Identities = 70/284 (24%), Positives = 98/284 (34%), Gaps = 80/284 (28%)
Query: 276 ASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKD 335
A+SC DE ++++ C C G C C PG+ P RPG C+ C C
Sbjct: 940 ATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPG-----GRCQLCECSGNIDP 994
Query: 336 CYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCR 395
D G C+ CL +T G +C C G++ + C
Sbjct: 995 MDPDACDPHT-------------GQCLRCLHHTEGPHCAHCKPGFH-----GQAARQSCH 1036
Query: 396 PCNCDPVGSLSSVCIK-DDLHSDLHNGKQP------------------------------ 424
C C+ +G+ C D H D +G+ P
Sbjct: 1037 RCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHGCQPCA 1096
Query: 425 ---------------GQCPCKEGYTGEKCDRCQLGYKDYP--TCVSCGCNPVGSASDEPC 467
GQC C+ G+ G C CQ + P C +C C+ G + + C
Sbjct: 1097 CHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQCHACDCDSRGIDTPQ-C 1155
Query: 468 ---TGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECF-CFG 507
TG C C+ V G CD+C GF + C C CFG
Sbjct: 1156 HRFTGHCSCRPGVSGVRCDQCARGFSGIFP----ACHPCHACFG 1195
Score = 87.4 bits (215), Expect = 2e-16
Identities = 53/152 (34%), Positives = 73/152 (48%), Gaps = 25/152 (16%)
Query: 358 GGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSD 417
GG C+ C +G C+ C GYY + C+ C C G+LSS+C K
Sbjct: 799 GGQCL-CKPGVVGRRCDLCAPGYYG------FGPTGCQACQCSHEGALSSLCEKTS---- 847
Query: 418 LHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYPTCVSCGCNPVGSASD-EPCTGPCV-CKE 475
GQC C+ G G +CDRCQ G +P+C C CN G A + TG C+ C++
Sbjct: 848 -------GQCLCRTGAFGLRCDRCQRGQWGFPSCRPCVCN--GHADECNTHTGACLGCRD 898
Query: 476 NVEGKACDRCKPGFYNLKEKNPRG--CSECFC 505
+ G+ C+RC GF+ + P G C C C
Sbjct: 899 HTGGEHCERCIAGFHG-DPRLPYGGQCRPCPC 929
Score = 81.6 bits (200), Expect = 1e-14
Identities = 45/123 (36%), Positives = 59/123 (47%), Gaps = 20/123 (16%)
Query: 396 PCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDY-PT-CVS 453
PC C+P GSLSS C GQC CK G G +CD C GY + PT C +
Sbjct: 782 PCQCNPQGSLSSEC-----------NPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGCQA 830
Query: 454 CGCNPVGSASD--EPCTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFCFGVSDV 511
C C+ G+ S E +G C+C+ G CDRC+ G + C C C G +D
Sbjct: 831 CQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFP-----SCRPCVCNGHADE 885
Query: 512 CSS 514
C++
Sbjct: 886 CNT 888
Score = 58.9 bits (141), Expect = 7e-08
Identities = 30/74 (40%), Positives = 36/74 (48%), Gaps = 8/74 (10%)
Query: 448 YPTCVSCGCNPVGSASDE--PCTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFC 505
Y + C CNP GS S E P G C+CK V G+ CD C PG+Y P GC C C
Sbjct: 777 YNGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGF---GPTGCQACQC 833
Query: 506 F---GVSDVCSSLS 516
+S +C S
Sbjct: 834 SHEGALSSLCEKTS 847
Score = 52.4 bits (124), Expect = 7e-06
Identities = 23/57 (40%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
Query: 1509 CDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDECEPRHI-LMETDCVSCDDECVGVL 1564
C CNP GS+ +C+ GQC+C+ G G RCD C P + T C +C G L
Sbjct: 783 CQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSHEGAL 839
Score = 39.3 bits (90), Expect = 0.061
Identities = 29/95 (30%), Positives = 37/95 (38%), Gaps = 24/95 (25%)
Query: 290 CQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCH-NKAKDCYYDESVAKQKKS 348
C C+ G C+RC PG+ W G C C+C A D DE
Sbjct: 491 CYCKRLVTGRGCDRCLPGH----W--GLSHDLLGCRPCDCDVGGALDPQCDE-------- 536
Query: 349 LNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRP 383
G G C +C Q+ +G CE GY+RP
Sbjct: 537 --------GTGQC-HCRQHMVGRRCEQVQPGYFRP 562
>gi|219842266 usherin isoform B [Homo sapiens]
Length = 5202
Score = 264 bits (674), Expect = 1e-69
Identities = 161/496 (32%), Positives = 227/496 (45%), Gaps = 67/496 (13%)
Query: 713 QGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAAECNVHGVCIACAHN----TTGVH 768
Q YT + + YY VD I G CQ CHGHA C+ C + T G+H
Sbjct: 492 QYYTTETAVNLRHRYYAVDEITISGRCQ---CHGHADNCDTTSQPYRCLCSQESFTEGLH 548
Query: 769 CEQCLPGFYGEPSRGTPGD------CQPCACPLTIASNNFSPTCHLN-----------DG 811
C++CLP + +P R GD C+PC C N+ S +CH N G
Sbjct: 549 CDRCLPLYNDKPFR--QGDQVYAFNCKPCQC------NSHSKSCHYNISVDPFPFEHFRG 600
Query: 812 DEVVCDWCAPGYSGAWCERCADGYY---GNPTVPGESCVPCDCSGNVDPSEAGHCDSVTG 868
VCD C +G CE C D ++ G + C PCDC + + CD + G
Sbjct: 601 GGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGG 660
Query: 869 ECLKCLGNTDGAHCERCADGFYG-DAVTAKNCRACECHVKGS--HSAVCHLETGLCDCKP 925
+C C + G C +C +GFY + C C C+ G+ CH +G C CK
Sbjct: 661 QC-NCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKA 719
Query: 926 NVTGQQCDQCLHGYYGLDSGH--GCRPCNCSVAGSVSDGCT-DEGQCHCVPGVAGKRCDR 982
NV G +CD C G+ L S + GC PC C++ GSV+ C GQC C G +CD
Sbjct: 720 NVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDT 779
Query: 983 CAHGFYAYQDGSCTPCDCPHTQN----TCDPETGECVCPPHTQGVKCEECEDGHW--GYD 1036
C FY +C CDC + C+ +TG+C+C P+ +G +C +C +G++ +
Sbjct: 780 CRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQN 839
Query: 1037 AEVGCQACNCSLVGSTHHR--CDVVTGHCQCKSKFGGRACDQC-----SLGYRDFPDCVP 1089
C CNC G+ + C+ TG C CK G C+QC +L +F C
Sbjct: 840 NSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQM 899
Query: 1090 CDCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFALRADNPLGCSP 1149
C+CD GT L +C + +G C C N G +CN+C+ G F + N GC P
Sbjct: 900 CECDSLGT------LPGTICDPI--SGQCLCVPNRQGRRCNQCQPG-FYISPGNATGCLP 950
Query: 1150 CFC---SGLSHLCSEL 1162
C C ++H+C+ L
Sbjct: 951 CSCHTTGAVNHICNSL 966
Score = 260 bits (665), Expect = 1e-68
Identities = 167/536 (31%), Positives = 238/536 (44%), Gaps = 116/536 (21%)
Query: 709 CECPQ-GYT-GTSCESCLSGY----YRVDGILFGGICQPCECHGHAAECNVH-------- 754
C C Q +T G C+ CL Y +R ++ C+PC+C+ H+ C+ +
Sbjct: 536 CLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPF 595
Query: 755 -------GVCIACAHNTTGVHCEQCLPGFY----GEPSRGTPGDCQPCACPLTIASNNFS 803
GVC C HNTTG +CE C F+ +PS C+PC C T+ + N S
Sbjct: 596 EHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPS--AIDVCKPCDCD-TVGTRNGS 652
Query: 804 PTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNPTVPGESCVPCDC--SGNVDPSEAG 861
C G C+ C SG C +C +G+Y + + C PC+C SG VD
Sbjct: 653 ILCDQIGGQ---CN-CKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITC 708
Query: 862 HCDSVTGECLKCLGNTDGAHCERCADGF-YGDAVTAKNCRACECHVKGSHSAVCHLETGL 920
H +S G+C KC N G C+ C GF + + C C+C++ GS + C+ +G
Sbjct: 709 HQNS--GQC-KCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQ 765
Query: 921 CDCKPNVTGQQCDQCLHGYYGLDSGHGCRPCNCSVAGSVSDGCTD--EGQCHCVPGVAGK 978
C+CK G QCD C +YGLD + C+ C+C AGS+ + GQC C P V G+
Sbjct: 766 CECKKEAKGLQCDTCRENFYGLDVTN-CKACDCDTAGSLPGTVCNAKTGQCICKPNVEGR 824
Query: 979 RCDRCAHG-FYAYQDGS--CTPCDC----------------------------------P 1001
+C++C G FY Q+ S C PC+C P
Sbjct: 825 QCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEP 884
Query: 1002 HTQN-----------------------TCDPETGECVCPPHTQGVKCEECEDGHW-GYDA 1037
H N CDP +G+C+C P+ QG +C +C+ G +
Sbjct: 885 HRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGN 944
Query: 1038 EVGCQACNCSLVGSTHHRCDVVTGHCQCK-SKFGGRACDQCSLGYRDFPD----CVPCDC 1092
GC C+C G+ +H C+ +TG C C+ + G+ CDQC Y F C PC+C
Sbjct: 945 ATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNC 1004
Query: 1093 DLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFALRADNPLGCS 1148
L G + C+L TG C CK+ V G +C+ C L +N LGCS
Sbjct: 1005 HLSGALNETCHL---------VTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGCS 1051
Score = 197 bits (500), Expect = 2e-49
Identities = 143/453 (31%), Positives = 206/453 (45%), Gaps = 61/453 (13%)
Query: 75 NPRERHPISHAIDG-TNNWWQSPSIQNGREYHW-VTITLDLRQ-VFQVAYVIIKAANAPR 131
NP E HP+S D W S N + + VTI++DL +QV Y+II+ + P+
Sbjct: 336 NP-EAHPLSFVNDNDVGTSWVSNVFTNITQLNQGVTISVDLENGQYQVFYIIIQFFS-PQ 393
Query: 132 PGNWILERSLDGTT-FSPWQYYAVSDSECLSRYNITPRRGPPTYRADDEVICTSYYSRLV 190
P ++R + + + WQY+A + + N D V C S
Sbjct: 394 PTEIRIQRKKENSLDWEDWQYFARNCGAFGMKNN-------GDLEKPDSVNCLQL-SNFT 445
Query: 191 PLEHGEIHTSLI----NGRPSADDL--SPKLLEFTSARYIRLRLQRIRTLNADLMTLSHR 244
P G + S++ N RP ++ +P L EF A IR + L HR
Sbjct: 446 PYSRGNVTFSILTPGPNYRPGYNNFYNTPSLQEFVKATQIRFHFHGQYYTTETAVNLRHR 505
Query: 245 EPKELDPIVTRRYYYSIKDISVGGMCICYGHASSCPWDETTKKLQCQC--EHNTCGESCN 302
YY++ +I++ G C C+GHA +C D T++ +C C E T G C+
Sbjct: 506 -------------YYAVDEITISGRCQCHGHADNC--DTTSQPYRCLCSQESFTEGLHCD 550
Query: 303 RCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKSLNTAGQFR-GGGVC 361
RC P Y+ +P+R G C+ C C++ +K C+Y+ SV FR GGGVC
Sbjct: 551 RCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFE-----HFRGGGGVC 605
Query: 362 INCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNG 421
+C NT G NCE C D ++R P + C+PC+CD VG+ + + D +
Sbjct: 606 DDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQI------- 658
Query: 422 KQPGQCPCKEGYTGEKCDRCQLGY-----KDYPTCVSCGCNPVGSA-SDEPC---TGPCV 472
GQC CK +G +C++CQ G+ D C C CN G+ D C +G C
Sbjct: 659 --GGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCK 716
Query: 473 CKENVEGKACDRCKPGFYNLKEKNPRGCSECFC 505
CK NV G CD C GF L+ N GC C C
Sbjct: 717 CKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQC 749
Score = 118 bits (296), Expect = 8e-26
Identities = 82/284 (28%), Positives = 109/284 (38%), Gaps = 45/284 (15%)
Query: 690 LDIASSNAIDLVVA---------ADVEHCECPQGYTGTSCESCLSG--YYRVDGILFGGI 738
LD+ + A D A A C C G C CL G Y R + +
Sbjct: 787 LDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSF---L 843
Query: 739 CQPCECH-----GHAAECNVHGVCIACAHNTTGVHCEQCLPGFYGEPSRGTPGDCQPCAC 793
C PC C + CN C TG+ C QC P Y CQ C C
Sbjct: 844 CLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQ-HCQMCEC 902
Query: 794 PLTIASNNFSPTCHLNDGDEVVCD------WCAPGYSGAWCERCADGYYGNPTVPGESCV 847
L +CD C P G C +C G+Y +P C+
Sbjct: 903 D------------SLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPG-NATGCL 949
Query: 848 PCDCSGNVDPSEAGH-CDSVTGECLKCLGNTDGAHCERCADGFYGDAVTAKNCRACECHV 906
PC C H C+S+TG+C+ + G C++C D ++G C+ C CH+
Sbjct: 950 PCSCHTT---GAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHL 1006
Query: 907 KGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLDSGH--GC 948
G+ + CHL TG C CK VTG +CD C+ LD + GC
Sbjct: 1007 SGALNETCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGC 1050
Score = 111 bits (278), Expect = 1e-23
Identities = 83/302 (27%), Positives = 132/302 (43%), Gaps = 57/302 (18%)
Query: 258 YYSIKDISVGGMCICYGHASSCPWDETT---KKLQCQCEHNTCGESCNRCCPGYHQ---- 310
+Y+++++ G C + S + T QC+C+ N G C+ C G+
Sbjct: 680 FYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSF 739
Query: 311 -----QPWRPGTVSSGNT-CEA----CNCHNKAK--------DCYYDESVAKQKK-SLNT 351
+P + S N C C C +AK + +Y V K +T
Sbjct: 740 NDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDT 799
Query: 352 AGQFRGG------GVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSL 405
AG G G CI C N G C C++G + + + + C PCNCD G++
Sbjct: 800 AGSLPGTVCNAKTGQCI-CKPNVEGRQCNKCLEGNFYLRQNNSFL---CLPCNCDKTGTI 855
Query: 406 SSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQ-----LGYKDYPTCVSCGCNPVG 460
+ L K GQCPCK G TG +C++C+ L ++ C C C+ +G
Sbjct: 856 NG---------SLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLG 906
Query: 461 SASD---EPCTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFCF---GVSDVCSS 514
+ +P +G C+C N +G+ C++C+PGFY + N GC C C V+ +C+S
Sbjct: 907 TLPGTICDPISGQCLCVPNRQGRRCNQCQPGFY-ISPGNATGCLPCSCHTTGAVNHICNS 965
Query: 515 LS 516
L+
Sbjct: 966 LT 967
Score = 105 bits (263), Expect = 5e-22
Identities = 63/212 (29%), Positives = 95/212 (44%), Gaps = 27/212 (12%)
Query: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDT---CDPNTGK 1418
C C +G C C G+ L + +D G C PC CN H C+P++G+
Sbjct: 715 CKCKANVIGLRCDHCNFGFKF--LRSFNDVG-------CEPCQCNLHGSVNKFCNPHSGQ 765
Query: 1419 CLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGDHDFRCDA 1478
C C G CD C +YG ++C C C A P V +C
Sbjct: 766 C-ECKKEAKGLQCDTCRENFYGL---DVTNCKACDCD---TAGSLPGTVCNAKTG-QC-I 816
Query: 1479 CLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGD--CDRTSGQCVCRLGASG 1536
C EG+ C +C + Q C C+C+ G+++G C++++GQC C+LG +G
Sbjct: 817 CKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTG 876
Query: 1537 LRCDECEPRHILMETD----CVSCDDECVGVL 1564
LRC++CEP + D C C+ + +G L
Sbjct: 877 LRCNQCEPHRYNLTIDNFQHCQMCECDSLGTL 908
Score = 100 bits (248), Expect = 3e-20
Identities = 64/207 (30%), Positives = 93/207 (44%), Gaps = 17/207 (8%)
Query: 1364 CPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCN-----NHSDTCDPNTGK 1418
C T G +C+ C + R G+D + C PC C+ N S CD G+
Sbjct: 608 CEHNTTGRNCELCKDYFFR---QVGADPSA---IDVCKPCDCDTVGTRNGSILCDQIGGQ 661
Query: 1419 CLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGDHDFRCDA 1478
C NC + +G C+ C +G+Y C+ C C S TC + +C A
Sbjct: 662 C-NCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCH-QNSGQCKCKA 719
Query: 1479 CLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLR 1538
++G C+ C+ + C+ C CN HGSV+ C+ SGQC C+ A GL+
Sbjct: 720 NVIGLR---CDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQ 776
Query: 1539 CDEC-EPRHILMETDCVSCDDECVGVL 1564
CD C E + L T+C +CD + G L
Sbjct: 777 CDTCRENFYGLDVTNCKACDCDTAGSL 803
Score = 99.0 bits (245), Expect = 6e-20
Identities = 60/202 (29%), Positives = 85/202 (42%), Gaps = 29/202 (14%)
Query: 1362 CVCPPG--TVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNT--- 1416
C+C T G C C P Y+ +G + C PC CN+HS +C N
Sbjct: 536 CLCSQESFTEGLHCDRCLPLYNDKPFR----QGDQVYAFNCKPCQCNSHSKSCHYNISVD 591
Query: 1417 -----------GKCLNCGDNTAGDHCDVCTSGYYGKVTGSASD---CALCACPHSPPASF 1462
G C +C NT G +C++C ++ +V S C C C +
Sbjct: 592 PFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNG 651
Query: 1463 SPTCVLEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGD-- 1520
S C G +C+ C G+ C +C + +Y + C C+CN G+V GD
Sbjct: 652 SILCDQIGG---QCN-CKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDIT 707
Query: 1521 CDRTSGQCVCRLGASGLRCDEC 1542
C + SGQC C+ GLRCD C
Sbjct: 708 CHQNSGQCKCKANVIGLRCDHC 729
Score = 99.0 bits (245), Expect = 6e-20
Identities = 95/337 (28%), Positives = 142/337 (42%), Gaps = 30/337 (8%)
Query: 2739 VELSIRTFASSGLIYYMAHQ-NQADYAVLQLHGGRLHFMFDLGKGRTKVS----HPALLS 2793
++ S RT GLI + A NQ +Y LQL GRL+F+FD +V+ H S
Sbjct: 1544 IKASFRTKVPEGLIVFAASPGNQEEYFALQLKKGRLYFLFDPQGSPVEVTTTNDHGKQYS 1603
Query: 2794 DGKWHTVKTDYVKRKGFITVDGRESPMVTVVGDGTMLDVEGLFYLGGLPSQYQ-ARKIGN 2852
DGKWH + + G IT+DG + ++ T++ +LGGLP Y RK
Sbjct: 1604 DGKWHEIIAIRHQAFGQITLDGIYTGSSAILNGSTVIGDNTGVFLGGLPRSYTILRKDPE 1663
Query: 2853 ITH-SIPACIGDV--------TVNSKQLDKDSPVSAFTV----NRCYAVAQEGTYFDGSG 2899
I C+ DV + + LD S V C A EG F G+G
Sbjct: 1664 IIQKGFVGCLKDVHFMKNYNPSAIWEPLDWQSSEEQINVYNSWEGCPASLNEGAQFLGAG 1723
Query: 2900 YAALVKEGYKVQSDVNITLEFRTSSQNGVLLGI-STAKVDAIGLELVDGKVLFHVNNGAG 2958
+ L + + I+ +FRT NG+LL + + D + +EL G + F +N
Sbjct: 1724 FLELHPYMFHGGMNFEISFKFRTDQLNGLLLFVYNKDGPDFLAMELKSGILTFRLNTSLA 1783
Query: 2959 RITAAYEPKTATVLCDGKWHTLQANKSKHRITLIVDGNAVGAESPHTQSTSVDTNNPIYV 3018
+ C+GKW+ + K I+ V+G A Q V N+P+YV
Sbjct: 1784 --FTQVDLLLGLSYCNGKWNKVIIKKEGSFISASVNGLMKHASESGDQPLVV--NSPVYV 1839
Query: 3019 GGYPA----GVKQKCLRSQTSFRGCLRKLALIKSPQV 3051
GG P + CL + F GC++ + + V
Sbjct: 1840 GGIPQELLNSYQHLCL--EQGFGGCMKDVKFTRGAVV 1874
Score = 96.3 bits (238), Expect = 4e-19
Identities = 62/194 (31%), Positives = 91/194 (46%), Gaps = 35/194 (18%)
Query: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNN----HSDTCDPNTG 1417
C C G G C C P HR L + + C C C++ CDP +G
Sbjct: 868 CPCKLGVTGLRCNQCEP--HRYNLTIDNFQH-------CQMCECDSLGTLPGTICDPISG 918
Query: 1418 KCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPA------SFSPTCVLEGD 1471
+CL C N G C+ C G+Y G+A+ C C+C H+ A S + CV +
Sbjct: 919 QCL-CVPNRQGRRCNQCQPGFYIS-PGNATGCLPCSC-HTTGAVNHICNSLTGQCVCQ-- 973
Query: 1472 HDFRCDACLLGYEGKHCERCSSSYYG-NPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVC 1530
DA + G + C++C Y+G +PQT G CQ C+C+ G+++ C +GQC C
Sbjct: 974 -----DASIAG---QRCDQCKDHYFGFDPQT--GRCQPCNCHLSGALNETCHLVTGQCFC 1023
Query: 1531 RLGASGLRCDECEP 1544
+ +G +CD C P
Sbjct: 1024 KQFVTGSKCDACVP 1037
Score = 92.4 bits (228), Expect = 6e-18
Identities = 82/302 (27%), Positives = 121/302 (40%), Gaps = 62/302 (20%)
Query: 244 REPKELDPIVTRRYYYSIKDISVGGMCICYGHASSCPWDETTKKL-QCQCEHNTCGESCN 302
+E K L R +Y + D++ C C A S P K QC C+ N G CN
Sbjct: 770 KEAKGLQCDTCRENFYGL-DVTNCKACDC-DTAGSLPGTVCNAKTGQCICKPNVEGRQCN 827
Query: 303 RCCPG--YHQQPW----------RPGTVSSGNTCEA----CNCH--------NKAKDCYY 338
+C G Y +Q + GT++ C C C N+ + Y
Sbjct: 828 KCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRY 887
Query: 339 DESVAK----QKKSLNTAGQFRG------GGVCINCLQNTMGINCETCIDGYYRPHKVSP 388
+ ++ Q ++ G G G C+ C+ N G C C G+Y +SP
Sbjct: 888 NLTIDNFQHCQMCECDSLGTLPGTICDPISGQCL-CVPNRQGRRCNQCQPGFY----ISP 942
Query: 389 YEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEG-YTGEKCDRCQLGYKD 447
C PC+C G+++ +C GQC C++ G++CD+C+ Y
Sbjct: 943 GNATGCLPCSCHTTGAVNHIC-----------NSLTGQCVCQDASIAGQRCDQCKDHYFG 991
Query: 448 YPT----CVSCGCNPVGSASDEPC---TGPCVCKENVEGKACDRCKPGFYNLKEKNPRGC 500
+ C C C+ G A +E C TG C CK+ V G CD C P +L N GC
Sbjct: 992 FDPQTGRCQPCNCHLSG-ALNETCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGC 1050
Query: 501 SE 502
S+
Sbjct: 1051 SK 1052
Score = 76.6 bits (187), Expect = 3e-13
Identities = 78/354 (22%), Positives = 150/354 (42%), Gaps = 45/354 (12%)
Query: 2136 STNYNTLTLNVKTQEPDNLLFYLGS-STASDFLAVEMRRGRVAFLWDLGSGSTRLEFPDF 2194
+T++ + + +T+ P+ L+ + S ++ A+++++GR+ FL+D + +
Sbjct: 1538 NTDFTGIKASFRTKVPEGLIVFAASPGNQEEYFALQLKKGRLYFLFDPQGSPVEVTTTND 1597
Query: 2195 ---PIDDNRWHSIHVARFGNIGSLSVKEMSSNQKSPTKTSKSPGTANVLDVNNSTLMFVG 2251
D +WH I R G +++ + + + S G ++T +F+G
Sbjct: 1598 HGKQYSDGKWHEIIAIRHQAFGQITLDGIYTGSSAILNGSTVIG--------DNTGVFLG 1649
Query: 2252 GLGGQ---IKKSPAVKVTHFKGCLGEAFL--NGKSIGLWNYIEREGK---------CRGC 2297
GL ++K P + F GCL + N +W ++ + GC
Sbjct: 1650 GLPRSYTILRKDPEIIQKGFVGCLKDVHFMKNYNPSAIWEPLDWQSSEEQINVYNSWEGC 1709
Query: 2298 FGSSQNEDPSFHFDGSGYSVVEKSL--PATVTQIIMLFNTFSPNGLLLYLGSYGTKDFLS 2355
+S NE F G+G+ + + +I F T NGLLL++ + DFL+
Sbjct: 1710 -PASLNEGAQFL--GAGFLELHPYMFHGGMNFEISFKFRTDQLNGLLLFVYNKDGPDFLA 1766
Query: 2356 IELFRG--RVKVMTDLGSGPITLLTDRRYNNGTWYKIAFQRNRKQGVLAVIDAYNTSNKE 2413
+EL G ++ T L + LL Y NG W K+ +K+G
Sbjct: 1767 MELKSGILTFRLNTSLAFTQVDLLLGLSYCNGKWNKVII---KKEGSFISASVNGLMKHA 1823
Query: 2414 TKQGETPGASSDLNRLDKDPIYVGGLPRSRV--VRRGVTTKSFVGCIKNLEISR 2465
++ G+ P + P+YVGG+P+ + + + F GC+K+++ +R
Sbjct: 1824 SESGDQP-------LVVNSPVYVGGIPQELLNSYQHLCLEQGFGGCMKDVKFTR 1870
Score = 75.1 bits (183), Expect = 1e-12
Identities = 55/189 (29%), Positives = 84/189 (44%), Gaps = 23/189 (12%)
Query: 1403 CSCNNHSDTCDPNTG--KCLNCGDN-TAGDHCDVCTSGYYGKVTGS-----ASDCALCAC 1454
C C+ H+D CD + +CL ++ T G HCD C Y K A +C C C
Sbjct: 518 CQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQC 577
Query: 1455 -PHSPPASFSPTCVLEGDHDFR-----CDACLLGYEGKHCERCSSSYY---GNPQTPGGS 1505
HS ++ + FR CD C G++CE C ++ G +
Sbjct: 578 NSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDV 637
Query: 1506 CQKCDCNPHGSVHGD--CDRTSGQCVCRLGASGLRCDECEPR-HILMETD---CVSCDDE 1559
C+ CDC+ G+ +G CD+ GQC C+ SG +C++C+ + L E D C C+
Sbjct: 638 CKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCN 697
Query: 1560 CVGVLLNDL 1568
G + D+
Sbjct: 698 TSGTVDGDI 706
Score = 72.8 bits (177), Expect = 5e-12
Identities = 98/432 (22%), Positives = 180/432 (41%), Gaps = 64/432 (14%)
Query: 2310 FDGSGYSVVEKS---LPATVTQIIMLFNTFSPNGLLLYLGSYGTKD-FLSIELFRGRVKV 2365
F G+GY S + T I F T P GL+++ S G ++ + +++L +GR+
Sbjct: 1522 FIGNGYCKFPSSTHPVNTDFTGIKASFRTKVPEGLIVFAASPGNQEEYFALQLKKGRLYF 1581
Query: 2366 MTDLGSGPITLLTD----RRYNNGTWYKIAFQRNRKQGVLAVIDAYNTSNKETKQGETPG 2421
+ D P+ + T ++Y++G W++I R++ G + + Y S+ G
Sbjct: 1582 LFDPQGSPVEVTTTNDHGKQYSDGKWHEIIAIRHQAFGQITLDGIYTGSSAILNGSTVIG 1641
Query: 2422 ASSDLNRLDKDPIYVGGLPRSRVVRRG---VTTKSFVGCIKNLEISRS------------ 2466
D +++GGLPRS + R + K FVGC+K++ ++
Sbjct: 1642 --------DNTGVFLGGLPRSYTILRKDPEIIQKGFVGCLKDVHFMKNYNPSAIWEPLDW 1693
Query: 2467 -TFDLLRNSYGVRKGCLLEPIRSVSFLKGGYIELPPKSLSPESEWLVT--FATTNSSGII 2523
+ + N Y +GC FL G++EL P + ++ F T +G++
Sbjct: 1694 QSSEEQINVYNSWEGCPASLNEGAQFLGAGFLELHPYMFHGGMNFEISFKFRTDQLNGLL 1753
Query: 2524 LAALGGDVEKRGDREEAHVPFFSVMLIGGNIEVHVNPGDGTGLRKALLHAPTG-TCSDGQ 2582
L D F ++ L G + +N T L + G + +G+
Sbjct: 1754 LFVYNKD----------GPDFLAMELKSGILTFRLN----TSLAFTQVDLLLGLSYCNGK 1799
Query: 2583 AHSISLVRNRRIITVQLDENNPVEMKLGTLVESRTINVSNLYVGGIPEGEGTSL--LTMR 2640
+ + + + I+ + N + + + S +YVGGIP+ S L +
Sbjct: 1800 WNKVIIKKEGSFISASV---NGLMKHASESGDQPLVVNSPVYVGGIPQELLNSYQHLCLE 1856
Query: 2641 RSFHGCIKNLIFN----LELLDFNSAVGHEQVDLDTCWLSERPKLAPDAEDSKLLPEPRA 2696
+ F GC+K++ F + L +S G +V+LD C LS + DS L+ + +
Sbjct: 1857 QGFGGCMKDVKFTRGAVVNLASVSS--GAVRVNLDGC-LSTDSAVNCRGNDSILVYQGK- 1912
Query: 2697 FPEQCVVDAALE 2708
EQ V + L+
Sbjct: 1913 --EQSVYEGGLQ 1922
>gi|219842259 usherin isoform A [Homo sapiens]
Length = 1546
Score = 264 bits (674), Expect = 1e-69
Identities = 161/496 (32%), Positives = 227/496 (45%), Gaps = 67/496 (13%)
Query: 713 QGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAAECNVHGVCIACAHN----TTGVH 768
Q YT + + YY VD I G CQ CHGHA C+ C + T G+H
Sbjct: 492 QYYTTETAVNLRHRYYAVDEITISGRCQ---CHGHADNCDTTSQPYRCLCSQESFTEGLH 548
Query: 769 CEQCLPGFYGEPSRGTPGD------CQPCACPLTIASNNFSPTCHLN-----------DG 811
C++CLP + +P R GD C+PC C N+ S +CH N G
Sbjct: 549 CDRCLPLYNDKPFR--QGDQVYAFNCKPCQC------NSHSKSCHYNISVDPFPFEHFRG 600
Query: 812 DEVVCDWCAPGYSGAWCERCADGYY---GNPTVPGESCVPCDCSGNVDPSEAGHCDSVTG 868
VCD C +G CE C D ++ G + C PCDC + + CD + G
Sbjct: 601 GGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGG 660
Query: 869 ECLKCLGNTDGAHCERCADGFYG-DAVTAKNCRACECHVKGS--HSAVCHLETGLCDCKP 925
+C C + G C +C +GFY + C C C+ G+ CH +G C CK
Sbjct: 661 QC-NCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKA 719
Query: 926 NVTGQQCDQCLHGYYGLDSGH--GCRPCNCSVAGSVSDGCT-DEGQCHCVPGVAGKRCDR 982
NV G +CD C G+ L S + GC PC C++ GSV+ C GQC C G +CD
Sbjct: 720 NVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDT 779
Query: 983 CAHGFYAYQDGSCTPCDCPHTQN----TCDPETGECVCPPHTQGVKCEECEDGHW--GYD 1036
C FY +C CDC + C+ +TG+C+C P+ +G +C +C +G++ +
Sbjct: 780 CRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQN 839
Query: 1037 AEVGCQACNCSLVGSTHHR--CDVVTGHCQCKSKFGGRACDQC-----SLGYRDFPDCVP 1089
C CNC G+ + C+ TG C CK G C+QC +L +F C
Sbjct: 840 NSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQM 899
Query: 1090 CDCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFALRADNPLGCSP 1149
C+CD GT L +C + +G C C N G +CN+C+ G F + N GC P
Sbjct: 900 CECDSLGT------LPGTICDPI--SGQCLCVPNRQGRRCNQCQPG-FYISPGNATGCLP 950
Query: 1150 CFC---SGLSHLCSEL 1162
C C ++H+C+ L
Sbjct: 951 CSCHTTGAVNHICNSL 966
Score = 260 bits (665), Expect = 1e-68
Identities = 167/536 (31%), Positives = 238/536 (44%), Gaps = 116/536 (21%)
Query: 709 CECPQ-GYT-GTSCESCLSGY----YRVDGILFGGICQPCECHGHAAECNVH-------- 754
C C Q +T G C+ CL Y +R ++ C+PC+C+ H+ C+ +
Sbjct: 536 CLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPF 595
Query: 755 -------GVCIACAHNTTGVHCEQCLPGFY----GEPSRGTPGDCQPCACPLTIASNNFS 803
GVC C HNTTG +CE C F+ +PS C+PC C T+ + N S
Sbjct: 596 EHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPS--AIDVCKPCDCD-TVGTRNGS 652
Query: 804 PTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNPTVPGESCVPCDC--SGNVDPSEAG 861
C G C+ C SG C +C +G+Y + + C PC+C SG VD
Sbjct: 653 ILCDQIGGQ---CN-CKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITC 708
Query: 862 HCDSVTGECLKCLGNTDGAHCERCADGF-YGDAVTAKNCRACECHVKGSHSAVCHLETGL 920
H +S G+C KC N G C+ C GF + + C C+C++ GS + C+ +G
Sbjct: 709 HQNS--GQC-KCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQ 765
Query: 921 CDCKPNVTGQQCDQCLHGYYGLDSGHGCRPCNCSVAGSVSDGCTD--EGQCHCVPGVAGK 978
C+CK G QCD C +YGLD + C+ C+C AGS+ + GQC C P V G+
Sbjct: 766 CECKKEAKGLQCDTCRENFYGLDVTN-CKACDCDTAGSLPGTVCNAKTGQCICKPNVEGR 824
Query: 979 RCDRCAHG-FYAYQDGS--CTPCDC----------------------------------P 1001
+C++C G FY Q+ S C PC+C P
Sbjct: 825 QCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEP 884
Query: 1002 HTQN-----------------------TCDPETGECVCPPHTQGVKCEECEDGHW-GYDA 1037
H N CDP +G+C+C P+ QG +C +C+ G +
Sbjct: 885 HRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGN 944
Query: 1038 EVGCQACNCSLVGSTHHRCDVVTGHCQCK-SKFGGRACDQCSLGYRDFPD----CVPCDC 1092
GC C+C G+ +H C+ +TG C C+ + G+ CDQC Y F C PC+C
Sbjct: 945 ATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNC 1004
Query: 1093 DLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFALRADNPLGCS 1148
L G + C+L TG C CK+ V G +C+ C L +N LGCS
Sbjct: 1005 HLSGALNETCHL---------VTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGCS 1051
Score = 197 bits (500), Expect = 2e-49
Identities = 143/453 (31%), Positives = 206/453 (45%), Gaps = 61/453 (13%)
Query: 75 NPRERHPISHAIDG-TNNWWQSPSIQNGREYHW-VTITLDLRQ-VFQVAYVIIKAANAPR 131
NP E HP+S D W S N + + VTI++DL +QV Y+II+ + P+
Sbjct: 336 NP-EAHPLSFVNDNDVGTSWVSNVFTNITQLNQGVTISVDLENGQYQVFYIIIQFFS-PQ 393
Query: 132 PGNWILERSLDGTT-FSPWQYYAVSDSECLSRYNITPRRGPPTYRADDEVICTSYYSRLV 190
P ++R + + + WQY+A + + N D V C S
Sbjct: 394 PTEIRIQRKKENSLDWEDWQYFARNCGAFGMKNN-------GDLEKPDSVNCLQL-SNFT 445
Query: 191 PLEHGEIHTSLI----NGRPSADDL--SPKLLEFTSARYIRLRLQRIRTLNADLMTLSHR 244
P G + S++ N RP ++ +P L EF A IR + L HR
Sbjct: 446 PYSRGNVTFSILTPGPNYRPGYNNFYNTPSLQEFVKATQIRFHFHGQYYTTETAVNLRHR 505
Query: 245 EPKELDPIVTRRYYYSIKDISVGGMCICYGHASSCPWDETTKKLQCQC--EHNTCGESCN 302
YY++ +I++ G C C+GHA +C D T++ +C C E T G C+
Sbjct: 506 -------------YYAVDEITISGRCQCHGHADNC--DTTSQPYRCLCSQESFTEGLHCD 550
Query: 303 RCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKSLNTAGQFR-GGGVC 361
RC P Y+ +P+R G C+ C C++ +K C+Y+ SV FR GGGVC
Sbjct: 551 RCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFE-----HFRGGGGVC 605
Query: 362 INCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNG 421
+C NT G NCE C D ++R P + C+PC+CD VG+ + + D +
Sbjct: 606 DDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQI------- 658
Query: 422 KQPGQCPCKEGYTGEKCDRCQLGY-----KDYPTCVSCGCNPVGSA-SDEPC---TGPCV 472
GQC CK +G +C++CQ G+ D C C CN G+ D C +G C
Sbjct: 659 --GGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCK 716
Query: 473 CKENVEGKACDRCKPGFYNLKEKNPRGCSECFC 505
CK NV G CD C GF L+ N GC C C
Sbjct: 717 CKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQC 749
Score = 118 bits (296), Expect = 8e-26
Identities = 82/284 (28%), Positives = 109/284 (38%), Gaps = 45/284 (15%)
Query: 690 LDIASSNAIDLVVA---------ADVEHCECPQGYTGTSCESCLSG--YYRVDGILFGGI 738
LD+ + A D A A C C G C CL G Y R + +
Sbjct: 787 LDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSF---L 843
Query: 739 CQPCECH-----GHAAECNVHGVCIACAHNTTGVHCEQCLPGFYGEPSRGTPGDCQPCAC 793
C PC C + CN C TG+ C QC P Y CQ C C
Sbjct: 844 CLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQ-HCQMCEC 902
Query: 794 PLTIASNNFSPTCHLNDGDEVVCD------WCAPGYSGAWCERCADGYYGNPTVPGESCV 847
L +CD C P G C +C G+Y +P C+
Sbjct: 903 D------------SLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPG-NATGCL 949
Query: 848 PCDCSGNVDPSEAGH-CDSVTGECLKCLGNTDGAHCERCADGFYGDAVTAKNCRACECHV 906
PC C H C+S+TG+C+ + G C++C D ++G C+ C CH+
Sbjct: 950 PCSCHTT---GAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHL 1006
Query: 907 KGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLDSGH--GC 948
G+ + CHL TG C CK VTG +CD C+ LD + GC
Sbjct: 1007 SGALNETCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGC 1050
Score = 111 bits (278), Expect = 1e-23
Identities = 83/302 (27%), Positives = 132/302 (43%), Gaps = 57/302 (18%)
Query: 258 YYSIKDISVGGMCICYGHASSCPWDETT---KKLQCQCEHNTCGESCNRCCPGYHQ---- 310
+Y+++++ G C + S + T QC+C+ N G C+ C G+
Sbjct: 680 FYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSF 739
Query: 311 -----QPWRPGTVSSGNT-CEA----CNCHNKAK--------DCYYDESVAKQKK-SLNT 351
+P + S N C C C +AK + +Y V K +T
Sbjct: 740 NDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDT 799
Query: 352 AGQFRGG------GVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSL 405
AG G G CI C N G C C++G + + + + C PCNCD G++
Sbjct: 800 AGSLPGTVCNAKTGQCI-CKPNVEGRQCNKCLEGNFYLRQNNSFL---CLPCNCDKTGTI 855
Query: 406 SSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQ-----LGYKDYPTCVSCGCNPVG 460
+ L K GQCPCK G TG +C++C+ L ++ C C C+ +G
Sbjct: 856 NG---------SLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLG 906
Query: 461 SASD---EPCTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFCF---GVSDVCSS 514
+ +P +G C+C N +G+ C++C+PGFY + N GC C C V+ +C+S
Sbjct: 907 TLPGTICDPISGQCLCVPNRQGRRCNQCQPGFY-ISPGNATGCLPCSCHTTGAVNHICNS 965
Query: 515 LS 516
L+
Sbjct: 966 LT 967
Score = 105 bits (263), Expect = 5e-22
Identities = 63/212 (29%), Positives = 95/212 (44%), Gaps = 27/212 (12%)
Query: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDT---CDPNTGK 1418
C C +G C C G+ L + +D G C PC CN H C+P++G+
Sbjct: 715 CKCKANVIGLRCDHCNFGFKF--LRSFNDVG-------CEPCQCNLHGSVNKFCNPHSGQ 765
Query: 1419 CLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGDHDFRCDA 1478
C C G CD C +YG ++C C C A P V +C
Sbjct: 766 C-ECKKEAKGLQCDTCRENFYGL---DVTNCKACDCD---TAGSLPGTVCNAKTG-QC-I 816
Query: 1479 CLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGD--CDRTSGQCVCRLGASG 1536
C EG+ C +C + Q C C+C+ G+++G C++++GQC C+LG +G
Sbjct: 817 CKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTG 876
Query: 1537 LRCDECEPRHILMETD----CVSCDDECVGVL 1564
LRC++CEP + D C C+ + +G L
Sbjct: 877 LRCNQCEPHRYNLTIDNFQHCQMCECDSLGTL 908
Score = 100 bits (248), Expect = 3e-20
Identities = 64/207 (30%), Positives = 93/207 (44%), Gaps = 17/207 (8%)
Query: 1364 CPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCN-----NHSDTCDPNTGK 1418
C T G +C+ C + R G+D + C PC C+ N S CD G+
Sbjct: 608 CEHNTTGRNCELCKDYFFR---QVGADPSA---IDVCKPCDCDTVGTRNGSILCDQIGGQ 661
Query: 1419 CLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGDHDFRCDA 1478
C NC + +G C+ C +G+Y C+ C C S TC + +C A
Sbjct: 662 C-NCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCH-QNSGQCKCKA 719
Query: 1479 CLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLR 1538
++G C+ C+ + C+ C CN HGSV+ C+ SGQC C+ A GL+
Sbjct: 720 NVIGLR---CDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQ 776
Query: 1539 CDEC-EPRHILMETDCVSCDDECVGVL 1564
CD C E + L T+C +CD + G L
Sbjct: 777 CDTCRENFYGLDVTNCKACDCDTAGSL 803
Score = 99.0 bits (245), Expect = 6e-20
Identities = 60/202 (29%), Positives = 85/202 (42%), Gaps = 29/202 (14%)
Query: 1362 CVCPPG--TVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNT--- 1416
C+C T G C C P Y+ +G + C PC CN+HS +C N
Sbjct: 536 CLCSQESFTEGLHCDRCLPLYNDKPFR----QGDQVYAFNCKPCQCNSHSKSCHYNISVD 591
Query: 1417 -----------GKCLNCGDNTAGDHCDVCTSGYYGKVTGSASD---CALCACPHSPPASF 1462
G C +C NT G +C++C ++ +V S C C C +
Sbjct: 592 PFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNG 651
Query: 1463 SPTCVLEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGD-- 1520
S C G +C+ C G+ C +C + +Y + C C+CN G+V GD
Sbjct: 652 SILCDQIGG---QCN-CKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDIT 707
Query: 1521 CDRTSGQCVCRLGASGLRCDEC 1542
C + SGQC C+ GLRCD C
Sbjct: 708 CHQNSGQCKCKANVIGLRCDHC 729
Score = 96.3 bits (238), Expect = 4e-19
Identities = 62/194 (31%), Positives = 91/194 (46%), Gaps = 35/194 (18%)
Query: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNN----HSDTCDPNTG 1417
C C G G C C P HR L + + C C C++ CDP +G
Sbjct: 868 CPCKLGVTGLRCNQCEP--HRYNLTIDNFQH-------CQMCECDSLGTLPGTICDPISG 918
Query: 1418 KCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPA------SFSPTCVLEGD 1471
+CL C N G C+ C G+Y G+A+ C C+C H+ A S + CV +
Sbjct: 919 QCL-CVPNRQGRRCNQCQPGFYIS-PGNATGCLPCSC-HTTGAVNHICNSLTGQCVCQ-- 973
Query: 1472 HDFRCDACLLGYEGKHCERCSSSYYG-NPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVC 1530
DA + G + C++C Y+G +PQT G CQ C+C+ G+++ C +GQC C
Sbjct: 974 -----DASIAG---QRCDQCKDHYFGFDPQT--GRCQPCNCHLSGALNETCHLVTGQCFC 1023
Query: 1531 RLGASGLRCDECEP 1544
+ +G +CD C P
Sbjct: 1024 KQFVTGSKCDACVP 1037
Score = 92.4 bits (228), Expect = 6e-18
Identities = 82/302 (27%), Positives = 121/302 (40%), Gaps = 62/302 (20%)
Query: 244 REPKELDPIVTRRYYYSIKDISVGGMCICYGHASSCPWDETTKKL-QCQCEHNTCGESCN 302
+E K L R +Y + D++ C C A S P K QC C+ N G CN
Sbjct: 770 KEAKGLQCDTCRENFYGL-DVTNCKACDC-DTAGSLPGTVCNAKTGQCICKPNVEGRQCN 827
Query: 303 RCCPG--YHQQPW----------RPGTVSSGNTCEA----CNCH--------NKAKDCYY 338
+C G Y +Q + GT++ C C C N+ + Y
Sbjct: 828 KCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRY 887
Query: 339 DESVAK----QKKSLNTAGQFRG------GGVCINCLQNTMGINCETCIDGYYRPHKVSP 388
+ ++ Q ++ G G G C+ C+ N G C C G+Y +SP
Sbjct: 888 NLTIDNFQHCQMCECDSLGTLPGTICDPISGQCL-CVPNRQGRRCNQCQPGFY----ISP 942
Query: 389 YEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEG-YTGEKCDRCQLGYKD 447
C PC+C G+++ +C GQC C++ G++CD+C+ Y
Sbjct: 943 GNATGCLPCSCHTTGAVNHIC-----------NSLTGQCVCQDASIAGQRCDQCKDHYFG 991
Query: 448 YPT----CVSCGCNPVGSASDEPC---TGPCVCKENVEGKACDRCKPGFYNLKEKNPRGC 500
+ C C C+ G A +E C TG C CK+ V G CD C P +L N GC
Sbjct: 992 FDPQTGRCQPCNCHLSG-ALNETCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGC 1050
Query: 501 SE 502
S+
Sbjct: 1051 SK 1052
Score = 75.1 bits (183), Expect = 1e-12
Identities = 55/189 (29%), Positives = 84/189 (44%), Gaps = 23/189 (12%)
Query: 1403 CSCNNHSDTCDPNTG--KCLNCGDN-TAGDHCDVCTSGYYGKVTGS-----ASDCALCAC 1454
C C+ H+D CD + +CL ++ T G HCD C Y K A +C C C
Sbjct: 518 CQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQC 577
Query: 1455 -PHSPPASFSPTCVLEGDHDFR-----CDACLLGYEGKHCERCSSSYY---GNPQTPGGS 1505
HS ++ + FR CD C G++CE C ++ G +
Sbjct: 578 NSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDV 637
Query: 1506 CQKCDCNPHGSVHGD--CDRTSGQCVCRLGASGLRCDECEPR-HILMETD---CVSCDDE 1559
C+ CDC+ G+ +G CD+ GQC C+ SG +C++C+ + L E D C C+
Sbjct: 638 CKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCN 697
Query: 1560 CVGVLLNDL 1568
G + D+
Sbjct: 698 TSGTVDGDI 706
>gi|148613884 netrin 1 [Homo sapiens]
Length = 604
Score = 248 bits (634), Expect = 5e-65
Identities = 167/520 (32%), Positives = 255/520 (49%), Gaps = 66/520 (12%)
Query: 1 MRGGVLLVLLLCVAAQ---CRQ-----RGLFPAILNLASNAHISTNATCGEKGPEMFCKL 52
+RGG L + AAQ C R P +N A + ++TCG + P +C +
Sbjct: 22 VRGGPGLSMFAGQAAQPDPCSDENGHPRRCIPDFVNAAFGKDVRVSSTCG-RPPARYCVV 80
Query: 53 VEHVPGRPVRNPQCRICDGNSANPRERHPISHAIDGTN----NWWQSPSIQNGREY-HWV 107
E R +R+ C +C N+++P++ HP + D N WQS +N ++ H V
Sbjct: 81 SERGEER-LRS--CHLC--NASDPKKAHPPAFLTDLNNPHNLTCWQS---ENYLQFPHNV 132
Query: 108 TITLDLRQVFQVAYVIIKAANAPRPGNWILERSLD-GTTFSPWQYYAVSDSECLSRYNIT 166
T+TL L + F+V YV ++ + PRP + + +S+D G T+ P+Q+Y+ ++C YN
Sbjct: 133 TLTLSLGKKFEVTYVSLQFCS-PRPESMAIYKSMDYGRTWVPFQFYS---TQCRKMYN-R 187
Query: 167 PRRGPPTYRADDEVICTSYYSRLVPLEHGEIHTSLINGRPSADDL--SPKLLEFTSARYI 224
P R P T + + E +CT ++ + PL G I S ++GRPSA D SP L ++ +A I
Sbjct: 188 PHRAPITKQNEQEAVCTDSHTDMRPLSGGLIAFSTLDGRPSAHDFDNSPVLQDWVTATDI 247
Query: 225 RLRLQRIRTLNADLMTLSHREPKELDPIVTRRYYYSIKDISVGGMCICYGHASSCPWDET 284
R+ R+ T E ++ + Y+Y++ D+ VGG C C GHA+ C D
Sbjct: 248 RVAFSRLHTFGD--------ENEDDSELARDSYFYAVSDLQVGGRCKCNGHAARCVRDRD 299
Query: 285 TKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAK 344
L C C HNT G C+RC P ++ +PW+ T N C ACNC+ A+ C ++ + K
Sbjct: 300 DS-LVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYK 358
Query: 345 QKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGS 404
+G+ + GGVC+NC NT G +C C +GYYR + C+ C+C PVG+
Sbjct: 359 ------LSGR-KSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGA 411
Query: 405 LSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYPTCVSCGCNPVGSASD 464
C + GQCPCK+G TG C+RC GY+ +P+
Sbjct: 412 AGKTC-----------NQTTGQCPCKDGVTGITCNRCAKGYQQ-------SRSPIAPCIK 453
Query: 465 EPCTGPCVCKENV-EGKACDR-CKPGFYNLKEKNPRGCSE 502
P P +V E + CD CK LK + C +
Sbjct: 454 IPVAPPTTAASSVEEPEDCDSYCKASKGKLKINMKKYCKK 493
Score = 92.4 bits (228), Expect = 6e-18
Identities = 52/156 (33%), Positives = 71/156 (45%), Gaps = 18/156 (11%)
Query: 800 NNFSPTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNP-----TVPGESCVPCDCS-- 852
N + C + D +VCD C +G C+RC +Y P CV C+C+
Sbjct: 288 NGHAARCVRDRDDSLVCD-CRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLH 346
Query: 853 -----GNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCADGFYGDA----VTAKNCRACE 903
N++ + S G CL C NT G HC C +G+Y D K C+AC+
Sbjct: 347 ARRCRFNMELYKLSGRKS-GGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACD 405
Query: 904 CHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGY 939
CH G+ C+ TG C CK VTG C++C GY
Sbjct: 406 CHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKGY 441
Score = 90.5 bits (223), Expect = 2e-17
Identities = 50/153 (32%), Positives = 71/153 (46%), Gaps = 13/153 (8%)
Query: 1403 CSCNNHSDTC--DPNTGKCLNCGDNTAGDHCDVCTSGYYGK-----VTGSASDCALCACP 1455
C CN H+ C D + +C NTAG CD C +Y + A++C C C
Sbjct: 285 CKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCN 344
Query: 1456 -HSPPASFSPTCV-LEGDHDFR-CDACLLGYEGKHCERCSSSYY---GNPQTPGGSCQKC 1509
H+ F+ L G C C G+HC C YY G P T +C+ C
Sbjct: 345 LHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKAC 404
Query: 1510 DCNPHGSVHGDCDRTSGQCVCRLGASGLRCDEC 1542
DC+P G+ C++T+GQC C+ G +G+ C+ C
Sbjct: 405 DCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRC 437
Score = 85.9 bits (211), Expect = 6e-16
Identities = 58/178 (32%), Positives = 76/178 (42%), Gaps = 20/178 (11%)
Query: 725 SGYYRVDGILFGGICQPCECHGHAAEC---NVHGVCIACAHNTTGVHCEQCLPGFYGEP- 780
S +Y V + GG C+C+GHAA C + C HNT G C++C P Y P
Sbjct: 271 SYFYAVSDLQVGG---RCKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPW 327
Query: 781 SRGT---PGDCQPCACPLTIASNNFSPTCHLNDGDEV--VCDWCAPGYSGAWCERCADGY 835
R T +C C C L F+ + G + VC C +G C C +GY
Sbjct: 328 QRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGY 387
Query: 836 Y---GNPTVPGESCVPCDCSGNVDPSEAGH-CDSVTGECLKCLGNTDGAHCERCADGF 889
Y G P ++C CDC AG C+ TG+C C G C RCA G+
Sbjct: 388 YRDMGKPITHRKACKACDCH---PVGAAGKTCNQTTGQC-PCKDGVTGITCNRCAKGY 441
Score = 70.5 bits (171), Expect = 2e-11
Identities = 49/175 (28%), Positives = 67/175 (38%), Gaps = 27/175 (15%)
Query: 933 DQCLHGYYGLDSGHGCRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCDRCAHGFY---- 988
D + L G C+ CN A V D D C C AG CDRC Y
Sbjct: 270 DSYFYAVSDLQVGGRCK-CNGHAARCVRDR-DDSLVCDCRHNTAGPECDRCKPFHYDRPW 327
Query: 989 ----AYQDGSCTPCDCPHTQNTCD-----------PETGECV-CPPHTQGVKCEECEDGH 1032
A + C C+C C G C+ C +T G C C++G+
Sbjct: 328 QRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGY 387
Query: 1033 WG-----YDAEVGCQACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGYR 1082
+ C+AC+C VG+ C+ TG C CK G C++C+ GY+
Sbjct: 388 YRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKGYQ 442
Score = 68.9 bits (167), Expect = 7e-11
Identities = 51/166 (30%), Positives = 61/166 (36%), Gaps = 25/166 (15%)
Query: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNT----- 1416
C C T G C C P ++ + R CV C+CN H+ C N
Sbjct: 304 CDCRHNTAGPECDRCKPFHYDRPWQRATAREANE----CVACNCNLHARRCRFNMELYKL 359
Query: 1417 ------GKCLNCGDNTAGDHCDVCTSGYY---GKVTGSASDCALCACPHSPPASFSPTCV 1467
G CLNC NTAG HC C GYY GK C C C P + TC
Sbjct: 360 SGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDC--HPVGAAGKTC- 416
Query: 1468 LEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNP 1513
+C C G G C RC+ Y ++P C K P
Sbjct: 417 --NQTTGQC-PCKDGVTGITCNRCAKGYQ-QSRSPIAPCIKIPVAP 458
Score = 67.4 bits (163), Expect = 2e-10
Identities = 52/182 (28%), Positives = 70/182 (38%), Gaps = 36/182 (19%)
Query: 709 CECPQGYTGTSCESCLSGYY----RVDGILFGGICQPCECHGHAAECNVH---------- 754
C+C G C+ C +Y + C C C+ HA C +
Sbjct: 304 CDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRK 363
Query: 755 --GVCIACAHNTTGVHCEQCLPGFY---GEPSRGTPGDCQPCAC-PLTIASNNFSPTCHL 808
GVC+ C HNT G HC C G+Y G+P C+ C C P+ A TC+
Sbjct: 364 SGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKA-CKACDCHPVGAAGK----TCNQ 418
Query: 809 NDGDEVVCDWCAPGYSGAWCERCADGYYGN-----PTVPGESCVPCDCSGNVDPSEAGHC 863
G C C G +G C RCA GY + P + P + +V+ E C
Sbjct: 419 TTGQ---CP-CKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVAPPTTAASSVEEPE--DC 472
Query: 864 DS 865
DS
Sbjct: 473 DS 474
Score = 65.5 bits (158), Expect = 8e-10
Identities = 46/149 (30%), Positives = 58/149 (38%), Gaps = 39/149 (26%)
Query: 1014 CVCPPHTQGVKCEECEDGHWGYDAEVG-------CQACNCSLVGSTHHRCDVVT------ 1060
C C +T G +C+ C+ H+ + C ACNC+L RC
Sbjct: 304 CDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHA---RRCRFNMELYKLS 360
Query: 1061 -----GHC-QCKSKFGGRACDQCSLGY-RDFPD-------CVPCDCDLRGTSGDACNLEQ 1106
G C C+ GR C C GY RD C CDC G +G CN
Sbjct: 361 GRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCN--- 417
Query: 1107 GLCGCVEETGACPCKENVFGPQCNECREG 1135
+ TG CPCK+ V G CN C +G
Sbjct: 418 ------QTTGQCPCKDGVTGITCNRCAKG 440
Score = 65.1 bits (157), Expect = 1e-09
Identities = 42/160 (26%), Positives = 62/160 (38%), Gaps = 32/160 (20%)
Query: 902 CECHVKGSHSAVCHLETG---LCDCKPNVTGQQCDQCLHGYYG-------LDSGHGCRPC 951
C+C+ H+A C + +CDC+ N G +CD+C +Y + C C
Sbjct: 285 CKCN---GHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVAC 341
Query: 952 NCSVAGS---------VSDGCTDEGQC-HCVPGVAGKRCDRCAHGFY------AYQDGSC 995
NC++ G G C +C AG+ C C G+Y +C
Sbjct: 342 NCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKAC 401
Query: 996 TPCDC---PHTQNTCDPETGECVCPPHTQGVKCEECEDGH 1032
CDC TC+ TG+C C G+ C C G+
Sbjct: 402 KACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKGY 441
Score = 42.4 bits (98), Expect = 0.007
Identities = 31/114 (27%), Positives = 46/114 (40%), Gaps = 15/114 (13%)
Query: 1036 DAEVGCQA-CNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGYRDFP--------- 1085
D +VG + CN R D + C C+ G CD+C + D P
Sbjct: 278 DLQVGGRCKCNGHAARCVRDRDDSLV--CDCRHNTAGPECDRCKPFHYDRPWQRATAREA 335
Query: 1086 -DCVPCDCDLRGTSGDACNLEQGLCGCVEETGAC-PCKENVFGPQCNECREGTF 1137
+CV C+C+L N+E + G C C+ N G C+ C+EG +
Sbjct: 336 NECVACNCNLHARRC-RFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYY 388
>gi|62868217 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 213 bits (541), Expect = 3e-54
Identities = 153/528 (28%), Positives = 229/528 (43%), Gaps = 90/528 (17%)
Query: 10 LLCVAAQCRQRGLFPAI--LNLASNAHISTNATCGEKGPEMFCKLVEHVPGRPVRNPQCR 67
LL C + +P + L + + ++TCG PE +C +C
Sbjct: 14 LLHAQQACSRGACYPPVGDLLVGRTRFLRASSTCGLTKPETYCTQYGEW------QMKCC 67
Query: 68 ICDGNSANPRERHPISHAID--GTNNWWQSPSIQNGREYHWVTITLDLRQVFQVAYVIIK 125
CD + H + + G WWQS + N V++ LDL + FQ+ V+++
Sbjct: 68 KCDSRQPHNYYSHRVENVASSSGPMRWWQSQNDVNP-----VSLQLDLDRRFQLQEVMME 122
Query: 126 AANAPRPGNWILERSLD-GTTFSPWQYYAVSDSECLSRYNITPRRGPPTYRADDEVICTS 184
P P ++ERS D G T+ +QY A ++C S + + P +++ +V C S
Sbjct: 123 F-QGPMPAGMLIERSSDFGKTWRVYQYLA---ADCTSTFPRVRQGRPQSWQ---DVRCQS 175
Query: 185 YYSRL-VPLEHGEIHTSL---INGRPSADDLSPKLLEFTSARYIRLRLQRIRTLNADLMT 240
R L G++ +L ++G P+ S K+ E +R+ R
Sbjct: 176 LPQRPNARLNGGKVQLNLMDLVSGIPATQ--SQKIQEVGEITNLRVNFTR---------- 223
Query: 241 LSHREPKELDPIVTRRY-----YYSIKDISVGGMCICYGHASSC---------PWDETTK 286
L P+ R Y YY++ + + G C C+GHA C P
Sbjct: 224 --------LAPVPQRGYHPPSAYYAVSQLRLQGSCFCHGHADRCAPKPGASAGPSTAVQV 275
Query: 287 KLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQK 346
C C+HNT G +C RC P Y+ +PWRP + C+ C+C+ ++ C++D +V
Sbjct: 276 HDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVF--- 332
Query: 347 KSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSL- 405
A Q GGVC NC +T G NCE C Y+R + E C C CDP G++
Sbjct: 333 ----AASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVP 388
Query: 406 SSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLG-----YKDYPTCVSCGCNPVG 460
+ C GQC CKE GE+CD C+ G Y + C C CN +G
Sbjct: 389 GAPC-----------DPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILG 437
Query: 461 SASDEPC---TGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFC 505
S D PC +G C+C NV G CD+C P Y+ K + +GC C C
Sbjct: 438 SRRDMPCDEESGRCLCLPNVVGPKCDQCAP--YHWKLASGQGCEPCAC 483
Score = 199 bits (507), Expect = 3e-50
Identities = 126/365 (34%), Positives = 159/365 (43%), Gaps = 61/365 (16%)
Query: 725 SGYYRVDGILFGGICQPCECHGHAAEC--------------NVHGVCIACAHNTTGVHCE 770
S YY V + G C CHGHA C VH VC+ C HNT G +CE
Sbjct: 236 SAYYAVSQLRLQG---SCFCHGHADRCAPKPGASAGPSTAVQVHDVCV-CQHNTAGPNCE 291
Query: 771 QCLPGFYGEPSRGTPG----DCQPCACPLTIASNNFSPTCHLNDGDEV--------VCDW 818
+C P + P R G +CQ C C N S TCH + VCD
Sbjct: 292 RCAPFYNNRPWRPAEGQDAHECQRCDC------NGHSETCHFDPAVFAASQGAYGGVCDN 345
Query: 819 CAPGYSGAWCERCADGYYGNPTVPG----ESCVPCDCSGNVDPSEA---GHCDSVTGECL 871
C G CERC Y+ N PG E+C+ C+C DP A CD VTG+C+
Sbjct: 346 CRDHTEGKNCERCQLHYFRNRR-PGASIQETCISCEC----DPDGAVPGAPCDPVTGQCV 400
Query: 872 KCLGNTDGAHCERCADGFYG-DAVTAKNCRACECHVKGSHSAV-CHLETGLCDCKPNVTG 929
C + G C+ C GF G + C C+C++ GS + C E+G C C PNV G
Sbjct: 401 -CKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVG 459
Query: 930 QQCDQCLHGYYGLDSGHGCRPCNCSVAGSVSDGCTD-EGQCHCVPGVAGKRCD-----RC 983
+CDQC ++ L SG GC PC C S+S C GQC C G G C +C
Sbjct: 460 PKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQC 519
Query: 984 AHGFYAYQDGSCTPCDCPHTQNT---CDPETGECVCPPHTQGVKCEECEDGHWG-YDAEV 1039
Y C CDC CD +G C+C P G +C++C+ G+ Y V
Sbjct: 520 PDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCV 579
Query: 1040 GCQAC 1044
C C
Sbjct: 580 ACHPC 584
Score = 181 bits (458), Expect = 1e-44
Identities = 114/353 (32%), Positives = 155/353 (43%), Gaps = 67/353 (18%)
Query: 849 CDCSGNVDP------SEAGHCDSV-TGECLKCLGNTDGAHCERCADGFYG-------DAV 894
C C G+ D + AG +V + C NT G +CERCA FY +
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAP-FYNNRPWRPAEGQ 308
Query: 895 TAKNCRACECHVKGSHSAVCHLET-----------GLCD-CKPNVTGQQCDQCLHGYY-- 940
A C+ C+C+ HS CH + G+CD C+ + G+ C++C Y+
Sbjct: 309 DAHECQRCDCN---GHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRN 365
Query: 941 ---GLDSGHGCRPCNCSVAGSVSDGCTDE--GQCHCVPGVAGKRCDRCAHGF----YAYQ 991
G C C C G+V D GQC C V G+RCD C GF YA
Sbjct: 366 RRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANP 425
Query: 992 DGSCTPCDC----PHTQNTCDPETGECVCPPHTQGVKCEECEDGHWGYDAEVGCQACNCS 1047
G C CDC CD E+G C+C P+ G KC++C HW + GC+ C C
Sbjct: 426 QG-CHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACD 484
Query: 1048 LVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGYRDFPD---------CVPCDCDLRGTS 1098
S +C+ TG C C+ FGG C ++ R PD C CDCD RGT
Sbjct: 485 PHNSLSPQCNQFTGQCPCREGFGGLMCSAAAI--RQCPDRTYGDVATGCRACDCDFRGTE 542
Query: 1099 GDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFALRADNPLGCSPCF 1151
G GC + +G C C+ + GP+C++C+ G + R + C PCF
Sbjct: 543 GP---------GCDKASGRCLCRPGLTGPRCDQCQRG-YCNRYPVCVACHPCF 585
Score = 135 bits (340), Expect = 6e-31
Identities = 100/331 (30%), Positives = 131/331 (39%), Gaps = 39/331 (11%)
Query: 693 ASSNAIDLVVAADVEHCECPQGYTGTSCESCLSGY----YRVDGILFGGICQPCECHGHA 748
AS+ V DV C C G +CE C Y +R CQ C+C+GH+
Sbjct: 265 ASAGPSTAVQVHDV--CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHS 322
Query: 749 AECNVH------------GVCIACAHNTTGVHCEQCLPGFY--GEPSRGTPGDCQPCACP 794
C+ GVC C +T G +CE+C ++ P C C C
Sbjct: 323 ETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECD 382
Query: 795 LTIASNNFSPTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNPTVPGESCVPCDCSGN 854
A C G V C G C+ C G+ G + C CDC N
Sbjct: 383 PDGAVP--GAPCDPVTGQCV----CKEHVQGERCDLCKPGFTGLTYANPQGCHRCDC--N 434
Query: 855 VDPSEAG-HCDSVTGECLKCLGNTDGAHCERCADGFYGDAVTAKNCRACECHVKGSHSAV 913
+ S CD +G CL CL N G C++CA ++ + + C C C S S
Sbjct: 435 ILGSRRDMPCDEESGRCL-CLPNVVGPKCDQCAP-YHWKLASGQGCEPCACDPHNSLSPQ 492
Query: 914 CHLETGLCDCKPNVTGQQCD-----QCLHGYYGLDSGHGCRPCNCSVAGSVSDGCTD-EG 967
C+ TG C C+ G C QC YG D GCR C+C G+ GC G
Sbjct: 493 CNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYG-DVATGCRACDCDFRGTEGPGCDKASG 551
Query: 968 QCHCVPGVAGKRCDRCAHGFYAYQDGSCTPC 998
+C C PG+ G RCD+C G Y + C C
Sbjct: 552 RCLCRPGLTGPRCDQCQRG-YCNRYPVCVAC 581
Score = 106 bits (264), Expect = 4e-22
Identities = 184/873 (21%), Positives = 315/873 (36%), Gaps = 164/873 (18%)
Query: 1362 CVCPPGTVGFSCQDCAPGY-HRGKLPA-GSDRGPRPLVAPCVPCSCNNHSDTC--DPNT- 1416
CVC T G +C+ CAP Y +R PA G D C C CN HS+TC DP
Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQD------AHECQRCDCNGHSETCHFDPAVF 332
Query: 1417 --------GKCLNCGDNTAGDHCDVCTSGYYGKVTGSAS---DCALCAC------PHSPP 1459
G C NC D+T G +C+ C Y+ AS C C C P +P
Sbjct: 333 AASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPC 392
Query: 1460 ASFSPTCVL-EGDHDFRCDACLLGYEG------KHCERCSSSYYGNPQ------------ 1500
+ CV E RCD C G+ G + C RC + G+ +
Sbjct: 393 DPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCL 452
Query: 1501 --------------------TPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLRCD 1540
G C+ C C+PH S+ C++ +GQC CR G GL C
Sbjct: 453 CLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCS 512
Query: 1541 -----ECEPR-HILMETDCVSCDDECVGVLLNDLDEI-GDAVLSLNLTG----------- 1582
+C R + + T C +CD + G D+ G + LTG
Sbjct: 513 AAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYC 572
Query: 1583 -IIPVPYGILSNLENTTKYLQESLLKENMQKDLGKIKLEGVAEETDNLQKKLTRMLASTQ 1641
PV + L+E L+ ++ G E L ++ + +
Sbjct: 573 NRYPVCVACHPCFQTYDADLREQALRFGRLRNATASLWSGPGLEDRGLASRILDAKSKIE 632
Query: 1642 KVNRATERIFKESQDLAIAIERLQMSITEIMEKTTLNQTLDEDFLLPNSTLQNMQQNGTS 1701
++ Q++A + +S+ ++ L+ L+E+ L L+++ ++
Sbjct: 633 QIRAVLSSPAVTEQEVAQVASAI-LSLRRTLQGLQLDLPLEEETLSLPRDLESLDRSFNG 691
Query: 1702 LLEIMQIRDFTQLHQNATLELKAAEDLLSQIQENYQKPLEELEVLKEAASHVLSKHNNEL 1761
LL + Q R Q + ++ + A +LS E + +++ +S +L + +
Sbjct: 692 LLTMYQ-RKREQFEKISSADPSGAFRMLSTAYEQSAQAAQQV----SDSSRLLDQLRDSR 746
Query: 1762 KAAEALVREAEAKMQESNHLLLMVNANLREFSD-----KKLHVQEEQNLTSELIVQG--- 1813
+ AE LVR+A + L+ + + D KL Q + + G
Sbjct: 747 REAERLVRQAGGGGGTGSPKLVALRLEMSSLPDLTPTFNKLCGNSRQMACTPISCPGELC 806
Query: 1814 ------------RGLIDAAAAQTDAVQDALEHLEDHQDKLLLWSAKIRHHIDDLVMHMSQ 1861
RG++ A E L +L IR + S
Sbjct: 807 PQDNGTACGSRCRGVLPRAGGAFLMAGQVAEQLRGFNAQLQRTRQMIRAAEESASQIQSS 866
Query: 1862 RNAVDLVYRAEDHAAE---------FQRLADVLY---SGLENIRNVSLNATSAAYVHYNI 1909
++ A E Q++ D L + I+ VS A A ++ +
Sbjct: 867 AQRLETQVSASRSQMEEDVRRTRLLIQQVRDFLTDPDTDAATIQEVS-EAVLALWLPTDS 925
Query: 1910 QSLIEESEELARDAHRTVTETSLLSESLVSNGKAAVQRSSRFLKEGNNLSRKLPGIALEL 1969
+++++ E+ A R +LS++ K + R+ R E + + ++
Sbjct: 926 ATVLQKMNEIQAIAARLPNVDLVLSQT-----KQDIARARRLQAEAEEARSRAHAVEGQV 980
Query: 1970 SE----LRNKTNRFQENAVEITRQTNESLLILR------------------AIPKGIRDK 2007
+ LR T QE A + + T+ SL +++ ++ K + D
Sbjct: 981 EDVVGNLRQGTVALQE-AQDTMQGTSRSLRLIQDRVAEVQQVLRPAEKLVTSMTKQLGDF 1039
Query: 2008 GAKTKELATSASQ---SAVSTLRDVAGLSQELLNTSASLSRVNTTLRETHQLLQDSTMAT 2064
+ +EL A Q AV + G S++ L+ R+ E L S+M
Sbjct: 1040 WTRMEELRHQARQQGAEAVQAQQLAEGASEQALSAQEGFERIKQKYAELKDRLGQSSMLG 1099
Query: 2065 LLAGRKVKDVEIQANLLF-------DRLKPLKM 2090
G +++ V+ +A LF DR+K +++
Sbjct: 1100 -EQGARIQSVKTEAEELFGETMEMMDRMKDMEL 1131
Score = 98.6 bits (244), Expect = 8e-20
Identities = 59/167 (35%), Positives = 76/167 (45%), Gaps = 26/167 (15%)
Query: 1403 CSCNNHSDTCDPNTGKCLN------------CGDNTAGDHCDVCTSGYYGKVTGSAS--- 1447
C C+ H+D C P G C NTAG +C+ C Y + A
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQD 309
Query: 1448 --DCALCACP-HSPPASFSPT--CVLEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQTP 1502
+C C C HS F P +G + CD C EGK+CERC Y+ N + P
Sbjct: 310 AHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRN-RRP 368
Query: 1503 GGS----CQKCDCNPHGSVHG-DCDRTSGQCVCRLGASGLRCDECEP 1544
G S C C+C+P G+V G CD +GQCVC+ G RCD C+P
Sbjct: 369 GASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKP 415
Score = 94.4 bits (233), Expect = 2e-18
Identities = 69/248 (27%), Positives = 101/248 (40%), Gaps = 51/248 (20%)
Query: 255 RRYYYSIKDISVGGMCICYGHASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWR 314
RR SI++ + C G P D T QC C+ + GE C+ C PG+
Sbjct: 366 RRPGASIQETCISCECDPDGAVPGAPCDPVTG--QCVCKEHVQGERCDLCKPGFTGL--- 420
Query: 315 PGTVSSGNTCEACNCH--NKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGIN 372
T ++ C C+C+ +D DE G C+ CL N +G
Sbjct: 421 --TYANPQGCHRCDCNILGSRRDMPCDEE----------------SGRCL-CLPNVVGPK 461
Query: 373 CETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEG 432
C+ C P+ + C PC CDP SLS C + GQCPC+EG
Sbjct: 462 CDQCA-----PYHWKLASGQGCEPCACDPHNSLSPQC-----------NQFTGQCPCREG 505
Query: 433 YTGEKCDRCQLG------YKDYPT-CVSCGCNPVGSASD--EPCTGPCVCKENVEGKACD 483
+ G C + Y D T C +C C+ G+ + +G C+C+ + G CD
Sbjct: 506 FGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCD 565
Query: 484 RCKPGFYN 491
+C+ G+ N
Sbjct: 566 QCQRGYCN 573
Score = 73.9 bits (180), Expect = 2e-12
Identities = 56/194 (28%), Positives = 73/194 (37%), Gaps = 47/194 (24%)
Query: 998 CDCPHTQNTCDPETGE-------------CVCPPHTQGVKCEECEDGH----W----GYD 1036
C C + C P+ G CVC +T G CE C + W G D
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQD 309
Query: 1037 AEVGCQACNCSLVGSTHHRCDVVTGHCQ---------CKSKFGGRACDQCSLGY------ 1081
A CQ C+C+ T H V Q C+ G+ C++C L Y
Sbjct: 310 AHE-CQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRP 368
Query: 1082 --RDFPDCVPCDCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFAL 1139
C+ C+CD G A C TG C CKE+V G +C+ C+ G L
Sbjct: 369 GASIQETCISCECDPDGAVPGA--------PCDPVTGQCVCKEHVQGERCDLCKPGFTGL 420
Query: 1140 RADNPLGCSPCFCS 1153
NP GC C C+
Sbjct: 421 TYANPQGCHRCDCN 434
>gi|62868215 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 213 bits (541), Expect = 3e-54
Identities = 153/528 (28%), Positives = 229/528 (43%), Gaps = 90/528 (17%)
Query: 10 LLCVAAQCRQRGLFPAI--LNLASNAHISTNATCGEKGPEMFCKLVEHVPGRPVRNPQCR 67
LL C + +P + L + + ++TCG PE +C +C
Sbjct: 14 LLHAQQACSRGACYPPVGDLLVGRTRFLRASSTCGLTKPETYCTQYGEW------QMKCC 67
Query: 68 ICDGNSANPRERHPISHAID--GTNNWWQSPSIQNGREYHWVTITLDLRQVFQVAYVIIK 125
CD + H + + G WWQS + N V++ LDL + FQ+ V+++
Sbjct: 68 KCDSRQPHNYYSHRVENVASSSGPMRWWQSQNDVNP-----VSLQLDLDRRFQLQEVMME 122
Query: 126 AANAPRPGNWILERSLD-GTTFSPWQYYAVSDSECLSRYNITPRRGPPTYRADDEVICTS 184
P P ++ERS D G T+ +QY A ++C S + + P +++ +V C S
Sbjct: 123 F-QGPMPAGMLIERSSDFGKTWRVYQYLA---ADCTSTFPRVRQGRPQSWQ---DVRCQS 175
Query: 185 YYSRL-VPLEHGEIHTSL---INGRPSADDLSPKLLEFTSARYIRLRLQRIRTLNADLMT 240
R L G++ +L ++G P+ S K+ E +R+ R
Sbjct: 176 LPQRPNARLNGGKVQLNLMDLVSGIPATQ--SQKIQEVGEITNLRVNFTR---------- 223
Query: 241 LSHREPKELDPIVTRRY-----YYSIKDISVGGMCICYGHASSC---------PWDETTK 286
L P+ R Y YY++ + + G C C+GHA C P
Sbjct: 224 --------LAPVPQRGYHPPSAYYAVSQLRLQGSCFCHGHADRCAPKPGASAGPSTAVQV 275
Query: 287 KLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQK 346
C C+HNT G +C RC P Y+ +PWRP + C+ C+C+ ++ C++D +V
Sbjct: 276 HDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVF--- 332
Query: 347 KSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSL- 405
A Q GGVC NC +T G NCE C Y+R + E C C CDP G++
Sbjct: 333 ----AASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVP 388
Query: 406 SSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLG-----YKDYPTCVSCGCNPVG 460
+ C GQC CKE GE+CD C+ G Y + C C CN +G
Sbjct: 389 GAPC-----------DPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILG 437
Query: 461 SASDEPC---TGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFC 505
S D PC +G C+C NV G CD+C P Y+ K + +GC C C
Sbjct: 438 SRRDMPCDEESGRCLCLPNVVGPKCDQCAP--YHWKLASGQGCEPCAC 483
Score = 199 bits (507), Expect = 3e-50
Identities = 126/365 (34%), Positives = 159/365 (43%), Gaps = 61/365 (16%)
Query: 725 SGYYRVDGILFGGICQPCECHGHAAEC--------------NVHGVCIACAHNTTGVHCE 770
S YY V + G C CHGHA C VH VC+ C HNT G +CE
Sbjct: 236 SAYYAVSQLRLQG---SCFCHGHADRCAPKPGASAGPSTAVQVHDVCV-CQHNTAGPNCE 291
Query: 771 QCLPGFYGEPSRGTPG----DCQPCACPLTIASNNFSPTCHLNDGDEV--------VCDW 818
+C P + P R G +CQ C C N S TCH + VCD
Sbjct: 292 RCAPFYNNRPWRPAEGQDAHECQRCDC------NGHSETCHFDPAVFAASQGAYGGVCDN 345
Query: 819 CAPGYSGAWCERCADGYYGNPTVPG----ESCVPCDCSGNVDPSEA---GHCDSVTGECL 871
C G CERC Y+ N PG E+C+ C+C DP A CD VTG+C+
Sbjct: 346 CRDHTEGKNCERCQLHYFRNRR-PGASIQETCISCEC----DPDGAVPGAPCDPVTGQCV 400
Query: 872 KCLGNTDGAHCERCADGFYG-DAVTAKNCRACECHVKGSHSAV-CHLETGLCDCKPNVTG 929
C + G C+ C GF G + C C+C++ GS + C E+G C C PNV G
Sbjct: 401 -CKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVG 459
Query: 930 QQCDQCLHGYYGLDSGHGCRPCNCSVAGSVSDGCTD-EGQCHCVPGVAGKRCD-----RC 983
+CDQC ++ L SG GC PC C S+S C GQC C G G C +C
Sbjct: 460 PKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQC 519
Query: 984 AHGFYAYQDGSCTPCDCPHTQNT---CDPETGECVCPPHTQGVKCEECEDGHWG-YDAEV 1039
Y C CDC CD +G C+C P G +C++C+ G+ Y V
Sbjct: 520 PDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCV 579
Query: 1040 GCQAC 1044
C C
Sbjct: 580 ACHPC 584
Score = 181 bits (458), Expect = 1e-44
Identities = 114/353 (32%), Positives = 155/353 (43%), Gaps = 67/353 (18%)
Query: 849 CDCSGNVDP------SEAGHCDSV-TGECLKCLGNTDGAHCERCADGFYG-------DAV 894
C C G+ D + AG +V + C NT G +CERCA FY +
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAP-FYNNRPWRPAEGQ 308
Query: 895 TAKNCRACECHVKGSHSAVCHLET-----------GLCD-CKPNVTGQQCDQCLHGYY-- 940
A C+ C+C+ HS CH + G+CD C+ + G+ C++C Y+
Sbjct: 309 DAHECQRCDCN---GHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRN 365
Query: 941 ---GLDSGHGCRPCNCSVAGSVSDGCTDE--GQCHCVPGVAGKRCDRCAHGF----YAYQ 991
G C C C G+V D GQC C V G+RCD C GF YA
Sbjct: 366 RRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANP 425
Query: 992 DGSCTPCDC----PHTQNTCDPETGECVCPPHTQGVKCEECEDGHWGYDAEVGCQACNCS 1047
G C CDC CD E+G C+C P+ G KC++C HW + GC+ C C
Sbjct: 426 QG-CHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACD 484
Query: 1048 LVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGYRDFPD---------CVPCDCDLRGTS 1098
S +C+ TG C C+ FGG C ++ R PD C CDCD RGT
Sbjct: 485 PHNSLSPQCNQFTGQCPCREGFGGLMCSAAAI--RQCPDRTYGDVATGCRACDCDFRGTE 542
Query: 1099 GDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFALRADNPLGCSPCF 1151
G GC + +G C C+ + GP+C++C+ G + R + C PCF
Sbjct: 543 GP---------GCDKASGRCLCRPGLTGPRCDQCQRG-YCNRYPVCVACHPCF 585
Score = 135 bits (340), Expect = 6e-31
Identities = 100/331 (30%), Positives = 131/331 (39%), Gaps = 39/331 (11%)
Query: 693 ASSNAIDLVVAADVEHCECPQGYTGTSCESCLSGY----YRVDGILFGGICQPCECHGHA 748
AS+ V DV C C G +CE C Y +R CQ C+C+GH+
Sbjct: 265 ASAGPSTAVQVHDV--CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHS 322
Query: 749 AECNVH------------GVCIACAHNTTGVHCEQCLPGFY--GEPSRGTPGDCQPCACP 794
C+ GVC C +T G +CE+C ++ P C C C
Sbjct: 323 ETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECD 382
Query: 795 LTIASNNFSPTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNPTVPGESCVPCDCSGN 854
A C G V C G C+ C G+ G + C CDC N
Sbjct: 383 PDGAVP--GAPCDPVTGQCV----CKEHVQGERCDLCKPGFTGLTYANPQGCHRCDC--N 434
Query: 855 VDPSEAG-HCDSVTGECLKCLGNTDGAHCERCADGFYGDAVTAKNCRACECHVKGSHSAV 913
+ S CD +G CL CL N G C++CA ++ + + C C C S S
Sbjct: 435 ILGSRRDMPCDEESGRCL-CLPNVVGPKCDQCAP-YHWKLASGQGCEPCACDPHNSLSPQ 492
Query: 914 CHLETGLCDCKPNVTGQQCD-----QCLHGYYGLDSGHGCRPCNCSVAGSVSDGCTD-EG 967
C+ TG C C+ G C QC YG D GCR C+C G+ GC G
Sbjct: 493 CNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYG-DVATGCRACDCDFRGTEGPGCDKASG 551
Query: 968 QCHCVPGVAGKRCDRCAHGFYAYQDGSCTPC 998
+C C PG+ G RCD+C G Y + C C
Sbjct: 552 RCLCRPGLTGPRCDQCQRG-YCNRYPVCVAC 581
Score = 106 bits (264), Expect = 4e-22
Identities = 184/873 (21%), Positives = 315/873 (36%), Gaps = 164/873 (18%)
Query: 1362 CVCPPGTVGFSCQDCAPGY-HRGKLPA-GSDRGPRPLVAPCVPCSCNNHSDTC--DPNT- 1416
CVC T G +C+ CAP Y +R PA G D C C CN HS+TC DP
Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQD------AHECQRCDCNGHSETCHFDPAVF 332
Query: 1417 --------GKCLNCGDNTAGDHCDVCTSGYYGKVTGSAS---DCALCAC------PHSPP 1459
G C NC D+T G +C+ C Y+ AS C C C P +P
Sbjct: 333 AASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPC 392
Query: 1460 ASFSPTCVL-EGDHDFRCDACLLGYEG------KHCERCSSSYYGNPQ------------ 1500
+ CV E RCD C G+ G + C RC + G+ +
Sbjct: 393 DPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCL 452
Query: 1501 --------------------TPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLRCD 1540
G C+ C C+PH S+ C++ +GQC CR G GL C
Sbjct: 453 CLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCS 512
Query: 1541 -----ECEPR-HILMETDCVSCDDECVGVLLNDLDEI-GDAVLSLNLTG----------- 1582
+C R + + T C +CD + G D+ G + LTG
Sbjct: 513 AAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYC 572
Query: 1583 -IIPVPYGILSNLENTTKYLQESLLKENMQKDLGKIKLEGVAEETDNLQKKLTRMLASTQ 1641
PV + L+E L+ ++ G E L ++ + +
Sbjct: 573 NRYPVCVACHPCFQTYDADLREQALRFGRLRNATASLWSGPGLEDRGLASRILDAKSKIE 632
Query: 1642 KVNRATERIFKESQDLAIAIERLQMSITEIMEKTTLNQTLDEDFLLPNSTLQNMQQNGTS 1701
++ Q++A + +S+ ++ L+ L+E+ L L+++ ++
Sbjct: 633 QIRAVLSSPAVTEQEVAQVASAI-LSLRRTLQGLQLDLPLEEETLSLPRDLESLDRSFNG 691
Query: 1702 LLEIMQIRDFTQLHQNATLELKAAEDLLSQIQENYQKPLEELEVLKEAASHVLSKHNNEL 1761
LL + Q R Q + ++ + A +LS E + +++ +S +L + +
Sbjct: 692 LLTMYQ-RKREQFEKISSADPSGAFRMLSTAYEQSAQAAQQV----SDSSRLLDQLRDSR 746
Query: 1762 KAAEALVREAEAKMQESNHLLLMVNANLREFSD-----KKLHVQEEQNLTSELIVQG--- 1813
+ AE LVR+A + L+ + + D KL Q + + G
Sbjct: 747 REAERLVRQAGGGGGTGSPKLVALRLEMSSLPDLTPTFNKLCGNSRQMACTPISCPGELC 806
Query: 1814 ------------RGLIDAAAAQTDAVQDALEHLEDHQDKLLLWSAKIRHHIDDLVMHMSQ 1861
RG++ A E L +L IR + S
Sbjct: 807 PQDNGTACGSRCRGVLPRAGGAFLMAGQVAEQLRGFNAQLQRTRQMIRAAEESASQIQSS 866
Query: 1862 RNAVDLVYRAEDHAAE---------FQRLADVLY---SGLENIRNVSLNATSAAYVHYNI 1909
++ A E Q++ D L + I+ VS A A ++ +
Sbjct: 867 AQRLETQVSASRSQMEEDVRRTRLLIQQVRDFLTDPDTDAATIQEVS-EAVLALWLPTDS 925
Query: 1910 QSLIEESEELARDAHRTVTETSLLSESLVSNGKAAVQRSSRFLKEGNNLSRKLPGIALEL 1969
+++++ E+ A R +LS++ K + R+ R E + + ++
Sbjct: 926 ATVLQKMNEIQAIAARLPNVDLVLSQT-----KQDIARARRLQAEAEEARSRAHAVEGQV 980
Query: 1970 SE----LRNKTNRFQENAVEITRQTNESLLILR------------------AIPKGIRDK 2007
+ LR T QE A + + T+ SL +++ ++ K + D
Sbjct: 981 EDVVGNLRQGTVALQE-AQDTMQGTSRSLRLIQDRVAEVQQVLRPAEKLVTSMTKQLGDF 1039
Query: 2008 GAKTKELATSASQ---SAVSTLRDVAGLSQELLNTSASLSRVNTTLRETHQLLQDSTMAT 2064
+ +EL A Q AV + G S++ L+ R+ E L S+M
Sbjct: 1040 WTRMEELRHQARQQGAEAVQAQQLAEGASEQALSAQEGFERIKQKYAELKDRLGQSSMLG 1099
Query: 2065 LLAGRKVKDVEIQANLLF-------DRLKPLKM 2090
G +++ V+ +A LF DR+K +++
Sbjct: 1100 -EQGARIQSVKTEAEELFGETMEMMDRMKDMEL 1131
Score = 98.6 bits (244), Expect = 8e-20
Identities = 59/167 (35%), Positives = 76/167 (45%), Gaps = 26/167 (15%)
Query: 1403 CSCNNHSDTCDPNTGKCLN------------CGDNTAGDHCDVCTSGYYGKVTGSAS--- 1447
C C+ H+D C P G C NTAG +C+ C Y + A
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQD 309
Query: 1448 --DCALCACP-HSPPASFSPT--CVLEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQTP 1502
+C C C HS F P +G + CD C EGK+CERC Y+ N + P
Sbjct: 310 AHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRN-RRP 368
Query: 1503 GGS----CQKCDCNPHGSVHG-DCDRTSGQCVCRLGASGLRCDECEP 1544
G S C C+C+P G+V G CD +GQCVC+ G RCD C+P
Sbjct: 369 GASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKP 415
Score = 94.4 bits (233), Expect = 2e-18
Identities = 69/248 (27%), Positives = 101/248 (40%), Gaps = 51/248 (20%)
Query: 255 RRYYYSIKDISVGGMCICYGHASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWR 314
RR SI++ + C G P D T QC C+ + GE C+ C PG+
Sbjct: 366 RRPGASIQETCISCECDPDGAVPGAPCDPVTG--QCVCKEHVQGERCDLCKPGFTGL--- 420
Query: 315 PGTVSSGNTCEACNCH--NKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGIN 372
T ++ C C+C+ +D DE G C+ CL N +G
Sbjct: 421 --TYANPQGCHRCDCNILGSRRDMPCDEE----------------SGRCL-CLPNVVGPK 461
Query: 373 CETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEG 432
C+ C P+ + C PC CDP SLS C + GQCPC+EG
Sbjct: 462 CDQCA-----PYHWKLASGQGCEPCACDPHNSLSPQC-----------NQFTGQCPCREG 505
Query: 433 YTGEKCDRCQLG------YKDYPT-CVSCGCNPVGSASD--EPCTGPCVCKENVEGKACD 483
+ G C + Y D T C +C C+ G+ + +G C+C+ + G CD
Sbjct: 506 FGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCD 565
Query: 484 RCKPGFYN 491
+C+ G+ N
Sbjct: 566 QCQRGYCN 573
Score = 73.9 bits (180), Expect = 2e-12
Identities = 56/194 (28%), Positives = 73/194 (37%), Gaps = 47/194 (24%)
Query: 998 CDCPHTQNTCDPETGE-------------CVCPPHTQGVKCEECEDGH----W----GYD 1036
C C + C P+ G CVC +T G CE C + W G D
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQD 309
Query: 1037 AEVGCQACNCSLVGSTHHRCDVVTGHCQ---------CKSKFGGRACDQCSLGY------ 1081
A CQ C+C+ T H V Q C+ G+ C++C L Y
Sbjct: 310 AHE-CQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRP 368
Query: 1082 --RDFPDCVPCDCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFAL 1139
C+ C+CD G A C TG C CKE+V G +C+ C+ G L
Sbjct: 369 GASIQETCISCECDPDGAVPGA--------PCDPVTGQCVCKEHVQGERCDLCKPGFTGL 420
Query: 1140 RADNPLGCSPCFCS 1153
NP GC C C+
Sbjct: 421 TYANPQGCHRCDCN 434
>gi|189083719 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 213 bits (541), Expect = 3e-54
Identities = 153/528 (28%), Positives = 229/528 (43%), Gaps = 90/528 (17%)
Query: 10 LLCVAAQCRQRGLFPAI--LNLASNAHISTNATCGEKGPEMFCKLVEHVPGRPVRNPQCR 67
LL C + +P + L + + ++TCG PE +C +C
Sbjct: 14 LLHAQQACSRGACYPPVGDLLVGRTRFLRASSTCGLTKPETYCTQYGEW------QMKCC 67
Query: 68 ICDGNSANPRERHPISHAID--GTNNWWQSPSIQNGREYHWVTITLDLRQVFQVAYVIIK 125
CD + H + + G WWQS + N V++ LDL + FQ+ V+++
Sbjct: 68 KCDSRQPHNYYSHRVENVASSSGPMRWWQSQNDVNP-----VSLQLDLDRRFQLQEVMME 122
Query: 126 AANAPRPGNWILERSLD-GTTFSPWQYYAVSDSECLSRYNITPRRGPPTYRADDEVICTS 184
P P ++ERS D G T+ +QY A ++C S + + P +++ +V C S
Sbjct: 123 F-QGPMPAGMLIERSSDFGKTWRVYQYLA---ADCTSTFPRVRQGRPQSWQ---DVRCQS 175
Query: 185 YYSRL-VPLEHGEIHTSL---INGRPSADDLSPKLLEFTSARYIRLRLQRIRTLNADLMT 240
R L G++ +L ++G P+ S K+ E +R+ R
Sbjct: 176 LPQRPNARLNGGKVQLNLMDLVSGIPATQ--SQKIQEVGEITNLRVNFTR---------- 223
Query: 241 LSHREPKELDPIVTRRY-----YYSIKDISVGGMCICYGHASSC---------PWDETTK 286
L P+ R Y YY++ + + G C C+GHA C P
Sbjct: 224 --------LAPVPQRGYHPPSAYYAVSQLRLQGSCFCHGHADRCAPKPGASAGPSTAVQV 275
Query: 287 KLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQK 346
C C+HNT G +C RC P Y+ +PWRP + C+ C+C+ ++ C++D +V
Sbjct: 276 HDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVF--- 332
Query: 347 KSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSL- 405
A Q GGVC NC +T G NCE C Y+R + E C C CDP G++
Sbjct: 333 ----AASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVP 388
Query: 406 SSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLG-----YKDYPTCVSCGCNPVG 460
+ C GQC CKE GE+CD C+ G Y + C C CN +G
Sbjct: 389 GAPC-----------DPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILG 437
Query: 461 SASDEPC---TGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFC 505
S D PC +G C+C NV G CD+C P Y+ K + +GC C C
Sbjct: 438 SRRDMPCDEESGRCLCLPNVVGPKCDQCAP--YHWKLASGQGCEPCAC 483
Score = 199 bits (507), Expect = 3e-50
Identities = 126/365 (34%), Positives = 159/365 (43%), Gaps = 61/365 (16%)
Query: 725 SGYYRVDGILFGGICQPCECHGHAAEC--------------NVHGVCIACAHNTTGVHCE 770
S YY V + G C CHGHA C VH VC+ C HNT G +CE
Sbjct: 236 SAYYAVSQLRLQG---SCFCHGHADRCAPKPGASAGPSTAVQVHDVCV-CQHNTAGPNCE 291
Query: 771 QCLPGFYGEPSRGTPG----DCQPCACPLTIASNNFSPTCHLNDGDEV--------VCDW 818
+C P + P R G +CQ C C N S TCH + VCD
Sbjct: 292 RCAPFYNNRPWRPAEGQDAHECQRCDC------NGHSETCHFDPAVFAASQGAYGGVCDN 345
Query: 819 CAPGYSGAWCERCADGYYGNPTVPG----ESCVPCDCSGNVDPSEA---GHCDSVTGECL 871
C G CERC Y+ N PG E+C+ C+C DP A CD VTG+C+
Sbjct: 346 CRDHTEGKNCERCQLHYFRNRR-PGASIQETCISCEC----DPDGAVPGAPCDPVTGQCV 400
Query: 872 KCLGNTDGAHCERCADGFYG-DAVTAKNCRACECHVKGSHSAV-CHLETGLCDCKPNVTG 929
C + G C+ C GF G + C C+C++ GS + C E+G C C PNV G
Sbjct: 401 -CKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVG 459
Query: 930 QQCDQCLHGYYGLDSGHGCRPCNCSVAGSVSDGCTD-EGQCHCVPGVAGKRCD-----RC 983
+CDQC ++ L SG GC PC C S+S C GQC C G G C +C
Sbjct: 460 PKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQC 519
Query: 984 AHGFYAYQDGSCTPCDCPHTQNT---CDPETGECVCPPHTQGVKCEECEDGHWG-YDAEV 1039
Y C CDC CD +G C+C P G +C++C+ G+ Y V
Sbjct: 520 PDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCV 579
Query: 1040 GCQAC 1044
C C
Sbjct: 580 ACHPC 584
Score = 181 bits (458), Expect = 1e-44
Identities = 114/353 (32%), Positives = 155/353 (43%), Gaps = 67/353 (18%)
Query: 849 CDCSGNVDP------SEAGHCDSV-TGECLKCLGNTDGAHCERCADGFYG-------DAV 894
C C G+ D + AG +V + C NT G +CERCA FY +
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAP-FYNNRPWRPAEGQ 308
Query: 895 TAKNCRACECHVKGSHSAVCHLET-----------GLCD-CKPNVTGQQCDQCLHGYY-- 940
A C+ C+C+ HS CH + G+CD C+ + G+ C++C Y+
Sbjct: 309 DAHECQRCDCN---GHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRN 365
Query: 941 ---GLDSGHGCRPCNCSVAGSVSDGCTDE--GQCHCVPGVAGKRCDRCAHGF----YAYQ 991
G C C C G+V D GQC C V G+RCD C GF YA
Sbjct: 366 RRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANP 425
Query: 992 DGSCTPCDC----PHTQNTCDPETGECVCPPHTQGVKCEECEDGHWGYDAEVGCQACNCS 1047
G C CDC CD E+G C+C P+ G KC++C HW + GC+ C C
Sbjct: 426 QG-CHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACD 484
Query: 1048 LVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGYRDFPD---------CVPCDCDLRGTS 1098
S +C+ TG C C+ FGG C ++ R PD C CDCD RGT
Sbjct: 485 PHNSLSPQCNQFTGQCPCREGFGGLMCSAAAI--RQCPDRTYGDVATGCRACDCDFRGTE 542
Query: 1099 GDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFALRADNPLGCSPCF 1151
G GC + +G C C+ + GP+C++C+ G + R + C PCF
Sbjct: 543 GP---------GCDKASGRCLCRPGLTGPRCDQCQRG-YCNRYPVCVACHPCF 585
Score = 135 bits (340), Expect = 6e-31
Identities = 100/331 (30%), Positives = 131/331 (39%), Gaps = 39/331 (11%)
Query: 693 ASSNAIDLVVAADVEHCECPQGYTGTSCESCLSGY----YRVDGILFGGICQPCECHGHA 748
AS+ V DV C C G +CE C Y +R CQ C+C+GH+
Sbjct: 265 ASAGPSTAVQVHDV--CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHS 322
Query: 749 AECNVH------------GVCIACAHNTTGVHCEQCLPGFY--GEPSRGTPGDCQPCACP 794
C+ GVC C +T G +CE+C ++ P C C C
Sbjct: 323 ETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECD 382
Query: 795 LTIASNNFSPTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNPTVPGESCVPCDCSGN 854
A C G V C G C+ C G+ G + C CDC N
Sbjct: 383 PDGAVP--GAPCDPVTGQCV----CKEHVQGERCDLCKPGFTGLTYANPQGCHRCDC--N 434
Query: 855 VDPSEAG-HCDSVTGECLKCLGNTDGAHCERCADGFYGDAVTAKNCRACECHVKGSHSAV 913
+ S CD +G CL CL N G C++CA ++ + + C C C S S
Sbjct: 435 ILGSRRDMPCDEESGRCL-CLPNVVGPKCDQCAP-YHWKLASGQGCEPCACDPHNSLSPQ 492
Query: 914 CHLETGLCDCKPNVTGQQCD-----QCLHGYYGLDSGHGCRPCNCSVAGSVSDGCTD-EG 967
C+ TG C C+ G C QC YG D GCR C+C G+ GC G
Sbjct: 493 CNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYG-DVATGCRACDCDFRGTEGPGCDKASG 551
Query: 968 QCHCVPGVAGKRCDRCAHGFYAYQDGSCTPC 998
+C C PG+ G RCD+C G Y + C C
Sbjct: 552 RCLCRPGLTGPRCDQCQRG-YCNRYPVCVAC 581
Score = 106 bits (264), Expect = 4e-22
Identities = 184/873 (21%), Positives = 315/873 (36%), Gaps = 164/873 (18%)
Query: 1362 CVCPPGTVGFSCQDCAPGY-HRGKLPA-GSDRGPRPLVAPCVPCSCNNHSDTC--DPNT- 1416
CVC T G +C+ CAP Y +R PA G D C C CN HS+TC DP
Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQD------AHECQRCDCNGHSETCHFDPAVF 332
Query: 1417 --------GKCLNCGDNTAGDHCDVCTSGYYGKVTGSAS---DCALCAC------PHSPP 1459
G C NC D+T G +C+ C Y+ AS C C C P +P
Sbjct: 333 AASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPC 392
Query: 1460 ASFSPTCVL-EGDHDFRCDACLLGYEG------KHCERCSSSYYGNPQ------------ 1500
+ CV E RCD C G+ G + C RC + G+ +
Sbjct: 393 DPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCL 452
Query: 1501 --------------------TPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLRCD 1540
G C+ C C+PH S+ C++ +GQC CR G GL C
Sbjct: 453 CLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCS 512
Query: 1541 -----ECEPR-HILMETDCVSCDDECVGVLLNDLDEI-GDAVLSLNLTG----------- 1582
+C R + + T C +CD + G D+ G + LTG
Sbjct: 513 AAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYC 572
Query: 1583 -IIPVPYGILSNLENTTKYLQESLLKENMQKDLGKIKLEGVAEETDNLQKKLTRMLASTQ 1641
PV + L+E L+ ++ G E L ++ + +
Sbjct: 573 NRYPVCVACHPCFQTYDADLREQALRFGRLRNATASLWSGPGLEDRGLASRILDAKSKIE 632
Query: 1642 KVNRATERIFKESQDLAIAIERLQMSITEIMEKTTLNQTLDEDFLLPNSTLQNMQQNGTS 1701
++ Q++A + +S+ ++ L+ L+E+ L L+++ ++
Sbjct: 633 QIRAVLSSPAVTEQEVAQVASAI-LSLRRTLQGLQLDLPLEEETLSLPRDLESLDRSFNG 691
Query: 1702 LLEIMQIRDFTQLHQNATLELKAAEDLLSQIQENYQKPLEELEVLKEAASHVLSKHNNEL 1761
LL + Q R Q + ++ + A +LS E + +++ +S +L + +
Sbjct: 692 LLTMYQ-RKREQFEKISSADPSGAFRMLSTAYEQSAQAAQQV----SDSSRLLDQLRDSR 746
Query: 1762 KAAEALVREAEAKMQESNHLLLMVNANLREFSD-----KKLHVQEEQNLTSELIVQG--- 1813
+ AE LVR+A + L+ + + D KL Q + + G
Sbjct: 747 REAERLVRQAGGGGGTGSPKLVALRLEMSSLPDLTPTFNKLCGNSRQMACTPISCPGELC 806
Query: 1814 ------------RGLIDAAAAQTDAVQDALEHLEDHQDKLLLWSAKIRHHIDDLVMHMSQ 1861
RG++ A E L +L IR + S
Sbjct: 807 PQDNGTACGSRCRGVLPRAGGAFLMAGQVAEQLRGFNAQLQRTRQMIRAAEESASQIQSS 866
Query: 1862 RNAVDLVYRAEDHAAE---------FQRLADVLY---SGLENIRNVSLNATSAAYVHYNI 1909
++ A E Q++ D L + I+ VS A A ++ +
Sbjct: 867 AQRLETQVSASRSQMEEDVRRTRLLIQQVRDFLTDPDTDAATIQEVS-EAVLALWLPTDS 925
Query: 1910 QSLIEESEELARDAHRTVTETSLLSESLVSNGKAAVQRSSRFLKEGNNLSRKLPGIALEL 1969
+++++ E+ A R +LS++ K + R+ R E + + ++
Sbjct: 926 ATVLQKMNEIQAIAARLPNVDLVLSQT-----KQDIARARRLQAEAEEARSRAHAVEGQV 980
Query: 1970 SE----LRNKTNRFQENAVEITRQTNESLLILR------------------AIPKGIRDK 2007
+ LR T QE A + + T+ SL +++ ++ K + D
Sbjct: 981 EDVVGNLRQGTVALQE-AQDTMQGTSRSLRLIQDRVAEVQQVLRPAEKLVTSMTKQLGDF 1039
Query: 2008 GAKTKELATSASQ---SAVSTLRDVAGLSQELLNTSASLSRVNTTLRETHQLLQDSTMAT 2064
+ +EL A Q AV + G S++ L+ R+ E L S+M
Sbjct: 1040 WTRMEELRHQARQQGAEAVQAQQLAEGASEQALSAQEGFERIKQKYAELKDRLGQSSMLG 1099
Query: 2065 LLAGRKVKDVEIQANLLF-------DRLKPLKM 2090
G +++ V+ +A LF DR+K +++
Sbjct: 1100 -EQGARIQSVKTEAEELFGETMEMMDRMKDMEL 1131
Score = 98.6 bits (244), Expect = 8e-20
Identities = 59/167 (35%), Positives = 76/167 (45%), Gaps = 26/167 (15%)
Query: 1403 CSCNNHSDTCDPNTGKCLN------------CGDNTAGDHCDVCTSGYYGKVTGSAS--- 1447
C C+ H+D C P G C NTAG +C+ C Y + A
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQD 309
Query: 1448 --DCALCACP-HSPPASFSPT--CVLEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQTP 1502
+C C C HS F P +G + CD C EGK+CERC Y+ N + P
Sbjct: 310 AHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRN-RRP 368
Query: 1503 GGS----CQKCDCNPHGSVHG-DCDRTSGQCVCRLGASGLRCDECEP 1544
G S C C+C+P G+V G CD +GQCVC+ G RCD C+P
Sbjct: 369 GASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKP 415
Score = 94.4 bits (233), Expect = 2e-18
Identities = 69/248 (27%), Positives = 101/248 (40%), Gaps = 51/248 (20%)
Query: 255 RRYYYSIKDISVGGMCICYGHASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWR 314
RR SI++ + C G P D T QC C+ + GE C+ C PG+
Sbjct: 366 RRPGASIQETCISCECDPDGAVPGAPCDPVTG--QCVCKEHVQGERCDLCKPGFTGL--- 420
Query: 315 PGTVSSGNTCEACNCH--NKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGIN 372
T ++ C C+C+ +D DE G C+ CL N +G
Sbjct: 421 --TYANPQGCHRCDCNILGSRRDMPCDEE----------------SGRCL-CLPNVVGPK 461
Query: 373 CETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEG 432
C+ C P+ + C PC CDP SLS C + GQCPC+EG
Sbjct: 462 CDQCA-----PYHWKLASGQGCEPCACDPHNSLSPQC-----------NQFTGQCPCREG 505
Query: 433 YTGEKCDRCQLG------YKDYPT-CVSCGCNPVGSASD--EPCTGPCVCKENVEGKACD 483
+ G C + Y D T C +C C+ G+ + +G C+C+ + G CD
Sbjct: 506 FGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCD 565
Query: 484 RCKPGFYN 491
+C+ G+ N
Sbjct: 566 QCQRGYCN 573
Score = 73.9 bits (180), Expect = 2e-12
Identities = 56/194 (28%), Positives = 73/194 (37%), Gaps = 47/194 (24%)
Query: 998 CDCPHTQNTCDPETGE-------------CVCPPHTQGVKCEECEDGH----W----GYD 1036
C C + C P+ G CVC +T G CE C + W G D
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQD 309
Query: 1037 AEVGCQACNCSLVGSTHHRCDVVTGHCQ---------CKSKFGGRACDQCSLGY------ 1081
A CQ C+C+ T H V Q C+ G+ C++C L Y
Sbjct: 310 AHE-CQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRP 368
Query: 1082 --RDFPDCVPCDCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFAL 1139
C+ C+CD G A C TG C CKE+V G +C+ C+ G L
Sbjct: 369 GASIQETCISCECDPDGAVPGA--------PCDPVTGQCVCKEHVQGERCDLCKPGFTGL 420
Query: 1140 RADNPLGCSPCFCS 1153
NP GC C C+
Sbjct: 421 TYANPQGCHRCDCN 434
>gi|93204871 netrin 4 [Homo sapiens]
Length = 628
Score = 205 bits (521), Expect = 6e-52
Identities = 149/489 (30%), Positives = 215/489 (43%), Gaps = 80/489 (16%)
Query: 13 VAAQCRQRGLFPAILNLASNAHISTNATCGEKGPEMFCKLVEHVPGRPVRNPQCRICDGN 72
V+++C ++ P + NLA + + TCG+ E++C E+ R P+C C N
Sbjct: 26 VSSRC-EKACNPRMGNLALGRKLWADTTCGQNATELYCFYSENTD-LTCRQPKCDKC--N 81
Query: 73 SANPRERHPISHAIDGT----NNWWQSPSIQNGREYHWVTITLDLRQVFQVAYVIIKAAN 128
+A P H S D + WWQS + H I LDL F ++I+
Sbjct: 82 AAYPHLAHLPSAMADSSFRFPRTWWQS-----AEDVHREKIQLDLEAEFYFTHLIVMF-K 135
Query: 129 APRPGNWILERSLD-GTTFSPWQYYAVSDSECLSRYNITPRRGPPTYRADDEVICTSYYS 187
+PRP +L+RS D G T+ P++Y+A + S + ++G ICTS YS
Sbjct: 136 SPRPAAMVLDRSQDFGKTWKPYKYFATNCSATFGLEDDVVKKG---------AICTSKYS 186
Query: 188 RLVPLEHGEIHTSLINGRPSADDLSP------KLLEFTSARYIRLRLQRIRTLNADLMTL 241
P GE+ ++ P D +P + L+ T+ R L+ Q DL
Sbjct: 187 SPFPCTGGEVIFKALS--PPYDTENPYSAKVQEQLKITNLRVQLLKRQSCPCQRNDL--- 241
Query: 242 SHREPKELDPIVTRRYYYSIKDISVGGMCICYGHASSC-----------PWDETTKKLQC 290
+ EP+ +Y+I D V G C C GHA C P +C
Sbjct: 242 -NEEPQHFT-------HYAIYDFIVKGSCFCNGHADQCIPVHGFRPVKAPGTFHMVHGKC 293
Query: 291 QCEHNTCGESCNRCCPGYHQQPWRP--GTVSSGNTCEACNCHNKAKDCYYDESVAKQKKS 348
C+HNT G C C P Y+ +PW G + N C C C+ A C++D +V +
Sbjct: 294 MCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWE---- 349
Query: 349 LNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGS---- 404
A R GGVC +C NT G C+ C G+YR + + C+PC+C PVGS
Sbjct: 350 ---ASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLP 406
Query: 405 LSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYPTCVSCGCNPVGSA-S 463
+SV D + G CPCK G G +CDRC +GY + GC P A S
Sbjct: 407 ANSVTFCDPSN---------GDCPCKPGVAGRRCDRCMVGYWGFG---DYGCRPCDCAGS 454
Query: 464 DEPCTGPCV 472
+P TG C+
Sbjct: 455 CDPITGDCI 463
Score = 122 bits (305), Expect = 7e-27
Identities = 79/255 (30%), Positives = 110/255 (43%), Gaps = 65/255 (25%)
Query: 849 CDCSGNVD---------PSEA-GHCDSVTGECLKCLGNTDGAHCERCA--------DGFY 890
C C+G+ D P +A G V G+C+ C NT G+HC+ CA +
Sbjct: 262 CFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCM-CKHNTAGSHCQHCAPLYNDRPWEAAD 320
Query: 891 GDAVTAKNCRACECHVKGSHSAVCHLET-----------GLCD-CKPNVTGQQCDQCLHG 938
G CR C+C+ H+ CH + G+CD C+ N GQ C +C G
Sbjct: 321 GKTGAPNECRTCKCN---GHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPG 377
Query: 939 YYG-----LDSGHGCRPCNCSVAGSV---SDGCT----DEGQCHCVPGVAGKRCDRCAHG 986
+Y + C+PC+C GS ++ T G C C PGVAG+RCDRC G
Sbjct: 378 FYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVG 437
Query: 987 FYAYQDGSCTPCDCPHTQNTCDPETGECVC---------------PPHTQGVKCEECEDG 1031
++ + D C PCDC +CDP TG+C+ P H + E ED
Sbjct: 438 YWGFGDYGCRPCDC---AGSCDPITGDCISSHTDIDWYHEVPDFRPVHNKSEPAWEWEDA 494
Query: 1032 HWGYDAEVGCQACNC 1046
G+ A + C C
Sbjct: 495 Q-GFSALLHSGKCEC 508
Score = 105 bits (263), Expect = 5e-22
Identities = 78/244 (31%), Positives = 105/244 (43%), Gaps = 45/244 (18%)
Query: 709 CECPQGYTGTSCESCLSGYY-----RVDGILFG-GICQPCECHGHAAECNVH-------- 754
C C G+ C+ C Y DG C+ C+C+GHA C+
Sbjct: 293 CMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEASG 352
Query: 755 ----GVCIACAHNTTGVHCEQCLPGFYGEPSR--GTPGDCQPCAC-PL--TIASNNFSPT 805
GVC C HNT G +C++C PGFY + R P C+PC+C P+ + N
Sbjct: 353 NRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTF 412
Query: 806 CHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDS 865
C ++GD C C PG +G C+RC GY+G C PCDC AG CD
Sbjct: 413 CDPSNGD---CP-CKPGVAGRRCDRCMVGYWG---FGDYGCRPCDC--------AGSCDP 457
Query: 866 VTGECLKCLGNTDGAHCERCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCDCKP 925
+TG+C+ + D H D V K+ A E SA+ H +G C+CK
Sbjct: 458 ITGDCISSHTDIDWYH--EVPD---FRPVHNKSEPAWEWEDAQGFSALLH--SGKCECKE 510
Query: 926 NVTG 929
G
Sbjct: 511 QTLG 514
Score = 100 bits (248), Expect = 3e-20
Identities = 60/200 (30%), Positives = 83/200 (41%), Gaps = 47/200 (23%)
Query: 742 CECHGHAAEC----------------NVHGVCIACAHNTTGVHCEQCLPGFYGEP----- 780
C C+GHA +C VHG C+ C HNT G HC+ C P + P
Sbjct: 262 CFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCM-CKHNTAGSHCQHCAPLYNDRPWEAAD 320
Query: 781 -SRGTPGDCQPCACPLTIASNNFSPTCHLN--------DGDEVVCDWCAPGYSGAWCERC 831
G P +C+ C C N + TCH + + VCD C G +C+RC
Sbjct: 321 GKTGAPNECRTCKC------NGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRC 374
Query: 832 ADGYYGN---PTVPGESCVPCDC----SGNVDPSEAGHCDSVTGECLKCLGNTDGAHCER 884
G+Y + P ++C PC C S + + CD G+C C G C+R
Sbjct: 375 KPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDC-PCKPGVAGRRCDR 433
Query: 885 CADGFYGDAVTAKNCRACEC 904
C G++G CR C+C
Sbjct: 434 CMVGYWG--FGDYGCRPCDC 451
Score = 86.7 bits (213), Expect = 3e-16
Identities = 53/174 (30%), Positives = 73/174 (41%), Gaps = 35/174 (20%)
Query: 1403 CSCNNHSDTCDPNTG---------------KCLNCGDNTAGDHCDVCTSGYYGKV----- 1442
C CN H+D C P G KC+ C NTAG HC C Y +
Sbjct: 262 CFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCM-CKHNTAGSHCQHCAPLYNDRPWEAAD 320
Query: 1443 --TGSASDCALCACPHSPPASFSPTCVLEGDHDFR---CDACLLGYEGKHCERCSSSYYG 1497
TG+ ++C C C V E + CD C EG++C+RC +Y
Sbjct: 321 GKTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYR 380
Query: 1498 NPQTPGGS---CQKCDCNPHGSVHGD------CDRTSGQCVCRLGASGLRCDEC 1542
+ + P + C+ C C+P GS CD ++G C C+ G +G RCD C
Sbjct: 381 DLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRC 434
Score = 85.9 bits (211), Expect = 6e-16
Identities = 58/182 (31%), Positives = 73/182 (40%), Gaps = 25/182 (13%)
Query: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTC--DPNT--- 1416
C+C T G CQ CAP Y+ A + P C C CN H+DTC D N
Sbjct: 293 CMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAP--NECRTCKCNGHADTCHFDVNVWEA 350
Query: 1417 ------GKCLNCGDNTAGDHCDVCTSGYYGKVTG--SASD-CALCACPHSPPASFSPTCV 1467
G C +C NT G +C C G+Y + SA D C C+C A V
Sbjct: 351 SGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSV 410
Query: 1468 LEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQ 1527
D C G G+ C+RC Y+G C+ CDC G CD +G
Sbjct: 411 TFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDY---GCRPCDC------AGSCDPITGD 461
Query: 1528 CV 1529
C+
Sbjct: 462 CI 463
Score = 75.9 bits (185), Expect = 6e-13
Identities = 50/161 (31%), Positives = 66/161 (40%), Gaps = 35/161 (21%)
Query: 967 GQCHCVPGVAGKRCDRCAHGF----YAYQDGS------CTPCDCPHTQNTCDPET----- 1011
G+C C AG C CA + + DG C C C +TC +
Sbjct: 291 GKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEA 350
Query: 1012 ------GECV-CPPHTQGVKCEECEDGHWG-----YDAEVGCQACNCSLVGS------TH 1053
G C C +T+G C+ C+ G + + A C+ C+C VGS +
Sbjct: 351 SGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSV 410
Query: 1054 HRCDVVTGHCQCKSKFGGRACDQCSLGYRDFPD--CVPCDC 1092
CD G C CK GR CD+C +GY F D C PCDC
Sbjct: 411 TFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDC 451
Score = 71.2 bits (173), Expect = 1e-11
Identities = 63/219 (28%), Positives = 84/219 (38%), Gaps = 54/219 (24%)
Query: 966 EGQCHCVPGVAGKRCDRC--AHGFYAYQDGSCTPCDCPHTQNTCDPETGECVCPPHTQGV 1023
+G C C D+C HGF P P T + G+C+C +T G
Sbjct: 259 KGSCFC-----NGHADQCIPVHGF--------RPVKAPGTFHMVH---GKCMCKHNTAGS 302
Query: 1024 KCEEC----EDGHW-GYDAEVG----CQACNCSLVGSTHH-----------RCDVVTGHC 1063
C+ C D W D + G C+ C C+ T H R V C
Sbjct: 303 HCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDC 362
Query: 1064 QCKSKFGGRACDQCSLG-YRDF------PD-CVPCDCDLRGTSGDACNLEQGLCGCVEET 1115
Q ++ G+ C +C G YRD PD C PC C G++ N + C
Sbjct: 363 QHNTE--GQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPAN---SVTFCDPSN 417
Query: 1116 GACPCKENVFGPQCNECREGTFALRADNPLGCSPCFCSG 1154
G CPCK V G +C+ C G + GC PC C+G
Sbjct: 418 GDCPCKPGVAGRRCDRCMVGYWGF---GDYGCRPCDCAG 453
Score = 38.1 bits (87), Expect = 0.14
Identities = 21/61 (34%), Positives = 26/61 (42%), Gaps = 15/61 (24%)
Query: 1361 NCVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKCL 1420
+C C PG G C C GY D G C PC C + +CDP TG C+
Sbjct: 419 DCPCKPGVAGRRCDRCMVGYW-----GFGDYG-------CRPCDC---AGSCDPITGDCI 463
Query: 1421 N 1421
+
Sbjct: 464 S 464
Score = 36.6 bits (83), Expect = 0.39
Identities = 17/51 (33%), Positives = 21/51 (41%), Gaps = 7/51 (13%)
Query: 469 GPCVCKENVEGKACDRCKPGFYNL-------KEKNPRGCSECFCFGVSDVC 512
G C+CK N G C C P + + K P C C C G +D C
Sbjct: 291 GKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTC 341
>gi|5453810 netrin 3 [Homo sapiens]
Length = 580
Score = 190 bits (483), Expect = 2e-47
Identities = 141/486 (29%), Positives = 219/486 (45%), Gaps = 76/486 (15%)
Query: 20 RGLFPAILNLASNAHISTNATCGEKGPEMFCKLVEHVPGRPVRNPQCRICDGNSANPRER 79
RG P ++N A + ++TCG P R CD +++PR
Sbjct: 38 RGCVPGLVNAALGREVLASSTCGR--------------------PATRACD--ASDPRRA 75
Query: 80 HP--ISHAIDGTNN--WWQSPSIQNGREYHWVTITLDLRQVFQVAYVIIKAANAPRPGNW 135
H + + GT + W+S S+ R VT+T+ L + F++ +V ++ +AP
Sbjct: 76 HSPALLTSPGGTASPLCWRSESLP--RAPLNVTLTVPLGKAFELVFVSLRFCSAPPASVA 133
Query: 136 ILERSLDGTTFSPWQYYAVSDSECLSRYNITPRRGPPTYRADDEVICTSYYSRLV-PLEH 194
+L+ G +++P +++ S C Y P E +C + + L P
Sbjct: 134 LLKSQDHGRSWAPLGFFS---SHCDLDYGRLPAPANGPAGPGPEALC--FPAPLAQPDGS 188
Query: 195 GEIHTSLINGRPSADDL--SPKLLEFTSARYIRLRLQRIRTLNADLMTLSHREPKELDPI 252
G + S+ + P DL SP L ++ +A +R+ L R T +P++++ +
Sbjct: 189 GLLAFSMQDSSPPGLDLDSSPVLQDWVTATDVRVVLTRPSTAG---------DPRDMEAV 239
Query: 253 VTRRYYYSIKDISVGGMCICYGHASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQP 312
V Y Y+ D+ VGG C C GHAS C D T L C C H T G C RC P Y +P
Sbjct: 240 VP--YSYAATDLQVGGRCKCNGHASRCLLD-TQGHLICDCRHGTEGPDCGRCKPFYCDRP 296
Query: 313 WRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGIN 372
W+ T + C AC+C+ A+ C ++ + + +G+ R GGVC+NC NT G +
Sbjct: 297 WQRATARESHACLACSCNGHARRCRFNMELYR------LSGR-RSGGVCLNCRHNTAGRH 349
Query: 373 CETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEG 432
C C +G+YR + + CR C+C PVG+ C + GQCPCK+G
Sbjct: 350 CHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTC-----------NQTTGQCPCKDG 398
Query: 433 YTGEKCDRCQLGYKDYPTCVSCGCNPVGSASDEPCTGPCVCKENVEGKACD-RCKP--GF 489
TG C+RC G++ +PV P GP V+ + CD CKP G
Sbjct: 399 VTGLTCNRCAPGFQQ-------SRSPVAPCVKTPIPGPTEDSSPVQPQDCDSHCKPARGS 451
Query: 490 YNLKEK 495
Y + K
Sbjct: 452 YRISLK 457
Score = 94.4 bits (233), Expect = 2e-18
Identities = 61/195 (31%), Positives = 80/195 (41%), Gaps = 26/195 (13%)
Query: 800 NNFSPTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNP-----TVPGESCVPCDCSGN 854
N + C L+ ++CD C G G C RC Y P +C+ C C+G+
Sbjct: 258 NGHASRCLLDTQGHLICD-CRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGH 316
Query: 855 VDPSE--------AGHCDSVTGECLKCLGNTDGAHCERCADGFYGDAVTA----KNCRAC 902
+G G CL C NT G HC C +GFY D A + CRAC
Sbjct: 317 ARRCRFNMELYRLSGRRSG--GVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRAC 374
Query: 903 ECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLDSGHGCRPC-NCSVAGSVSD 961
+CH G+ C+ TG C CK VTG C++C G+ S PC + G D
Sbjct: 375 DCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGFQ--QSRSPVAPCVKTPIPGPTED 432
Query: 962 GCTDEGQ---CHCVP 973
+ Q HC P
Sbjct: 433 SSPVQPQDCDSHCKP 447
Score = 80.5 bits (197), Expect = 2e-14
Identities = 55/189 (29%), Positives = 73/189 (38%), Gaps = 25/189 (13%)
Query: 709 CECPQGYTGTSCESCLSGY----YRVDGILFGGICQPCECHGHAAECNVH---------- 754
C+C G G C C Y ++ C C C+GHA C +
Sbjct: 274 CDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGRR 333
Query: 755 --GVCIACAHNTTGVHCEQCLPGFYGEPSRGTPG--DCQPCAC-PLTIASNNFSPT---C 806
GVC+ C HNT G HC C GFY +P R C+ C C P+ A + T C
Sbjct: 334 SGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQC 393
Query: 807 HLNDG-DEVVCDWCAPGY--SGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHC 863
DG + C+ CAPG+ S + C PT P DC + P+ +
Sbjct: 394 PCKDGVTGLTCNRCAPGFQQSRSPVAPCVKTPIPGPTEDSSPVQPQDCDSHCKPARGSYR 453
Query: 864 DSVTGECLK 872
S+ C K
Sbjct: 454 ISLKKFCKK 462
Score = 77.4 bits (189), Expect = 2e-13
Identities = 47/155 (30%), Positives = 68/155 (43%), Gaps = 13/155 (8%)
Query: 1403 CSCNNHSDTC--DPNTGKCLNCGDNTAGDHCDVCTSGY----YGKVTGSASD-CALCACP 1455
C CN H+ C D +C T G C C Y + + T S C C+C
Sbjct: 255 CKCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCN 314
Query: 1456 -HSPPASFSPTCV-LEGDHDFR-CDACLLGYEGKHCERCSSSYYGNPQ---TPGGSCQKC 1509
H+ F+ L G C C G+HC C +Y +P + +C+ C
Sbjct: 315 GHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRAC 374
Query: 1510 DCNPHGSVHGDCDRTSGQCVCRLGASGLRCDECEP 1544
DC+P G+ C++T+GQC C+ G +GL C+ C P
Sbjct: 375 DCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAP 409
Score = 73.2 bits (178), Expect = 4e-12
Identities = 53/169 (31%), Positives = 67/169 (39%), Gaps = 42/169 (24%)
Query: 849 CDCSGNVDP---SEAGH--CDSVTGECLKCLGNTDGAHCERCADGFYGDA----VTAKN- 898
C C+G+ GH CD C T+G C RC FY D TA+
Sbjct: 255 CKCNGHASRCLLDTQGHLICD--------CRHGTEGPDCGRCKP-FYCDRPWQRATARES 305
Query: 899 --CRACECHVKGSHSAVCHLET-----------GLC-DCKPNVTGQQCDQCLHGYY---- 940
C AC C+ H+ C G+C +C+ N G+ C C G+Y
Sbjct: 306 HACLACSCN---GHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPG 362
Query: 941 -GLDSGHGCRPCNCSVAGSVSDGCTDE-GQCHCVPGVAGKRCDRCAHGF 987
L CR C+C G+ C GQC C GV G C+RCA GF
Sbjct: 363 RALSDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGF 411
Score = 72.0 bits (175), Expect = 8e-12
Identities = 64/220 (29%), Positives = 86/220 (39%), Gaps = 31/220 (14%)
Query: 690 LDIASSNAI-DLVVAADVEHCECPQGYTGT--SCESCLSGYYRVDGILFGGICQPCECHG 746
LD+ SS + D V A DV G E+ + Y + GG C+C+G
Sbjct: 203 LDLDSSPVLQDWVTATDVRVVLTRPSTAGDPRDMEAVVPYSYAATDLQVGG---RCKCNG 259
Query: 747 HAAECNV----HGVCIACAHNTTGVHCEQCLPGFYGEP-SRGTPGDCQPCACPLTIASNN 801
HA+ C + H +C C H T G C +C P + P R T + C L + N
Sbjct: 260 HASRCLLDTQGHLIC-DCRHGTEGPDCGRCKPFYCDRPWQRATARESHAC---LACSCNG 315
Query: 802 FSPTCHLN--------DGDEVVCDWCAPGYSGAWCERCADGYYGNP---TVPGESCVPCD 850
+ C N VC C +G C C +G+Y +P +C CD
Sbjct: 316 HARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACD 375
Query: 851 CSGNVDPSEAGH-CDSVTGECLKCLGNTDGAHCERCADGF 889
C AG C+ TG+C C G C RCA GF
Sbjct: 376 CH---PVGAAGKTCNQTTGQC-PCKDGVTGLTCNRCAPGF 411
Score = 69.3 bits (168), Expect = 5e-11
Identities = 50/159 (31%), Positives = 61/159 (38%), Gaps = 21/159 (13%)
Query: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNT----- 1416
C C GT G C C P Y + R C+ CSCN H+ C N
Sbjct: 274 CDCRHGTEGPDCGRCKPFYCDRPWQRATARESHA----CLACSCNGHARRCRFNMELYRL 329
Query: 1417 ------GKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALC-ACPHSPPASFSPTCVLE 1469
G CLNC NTAG HC C G+Y + SD C AC P + TC
Sbjct: 330 SGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTC--- 386
Query: 1470 GDHDFRCDACLLGYEGKHCERCSSSYYGNPQTPGGSCQK 1508
+C C G G C RC+ + ++P C K
Sbjct: 387 NQTTGQC-PCKDGVTGLTCNRCAPGFQ-QSRSPVAPCVK 423
Score = 59.7 bits (143), Expect = 4e-08
Identities = 41/149 (27%), Positives = 56/149 (37%), Gaps = 28/149 (18%)
Query: 969 CHCVPGVAGKRCDRCAHGFY---------AYQDGSCTPCDCPHTQNTCD----------- 1008
C C G G C RC FY A + +C C C C
Sbjct: 274 CDCRHGTEGPDCGRCKP-FYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGR 332
Query: 1009 PETGECV-CPPHTQGVKCEECEDGHWGYDAEV-----GCQACNCSLVGSTHHRCDVVTGH 1062
G C+ C +T G C C +G + C+AC+C VG+ C+ TG
Sbjct: 333 RSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQ 392
Query: 1063 CQCKSKFGGRACDQCSLGYRDFPDCV-PC 1090
C CK G C++C+ G++ V PC
Sbjct: 393 CPCKDGVTGLTCNRCAPGFQQSRSPVAPC 421
Score = 55.5 bits (132), Expect = 8e-07
Identities = 46/161 (28%), Positives = 54/161 (33%), Gaps = 47/161 (29%)
Query: 998 CDCPHTQNTCDPETGEC---VCPPHTQGVKCEECEDGHWGYDAEVGCQACNCSLVGSTHH 1054
CDC H T P+ G C C Q E C AC+C+
Sbjct: 274 CDCRH--GTEGPDCGRCKPFYCDRPWQRATARESH----------ACLACSCN---GHAR 318
Query: 1055 RCDVVT-----------GHC-QCKSKFGGRACDQCSLGYRDFPD--------CVPCDCDL 1094
RC G C C+ GR C C G+ P C CDC
Sbjct: 319 RCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHP 378
Query: 1095 RGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREG 1135
G +G CN + TG CPCK+ V G CN C G
Sbjct: 379 VGAAGKTCN---------QTTGQCPCKDGVTGLTCNRCAPG 410
Score = 37.7 bits (86), Expect = 0.18
Identities = 19/61 (31%), Positives = 26/61 (42%), Gaps = 8/61 (13%)
Query: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAG-----SDRGPRPLVAPCVPCSCNNHSDTCDPNT 1416
C C G G +C CAPG+ + + P GP +P P C++H C P
Sbjct: 393 CPCKDGVTGLTCNRCAPGFQQSRSPVAPCVKTPIPGPTEDSSPVQPQDCDSH---CKPAR 449
Query: 1417 G 1417
G
Sbjct: 450 G 450
Score = 35.8 bits (81), Expect = 0.67
Identities = 37/134 (27%), Positives = 50/134 (37%), Gaps = 22/134 (16%)
Query: 1036 DAEVGCQACNCSLVGSTHHRCDVVT-GH--CQCKSKFGGRACDQCSLGYRDFP------- 1085
D +VG + C C+ S RC + T GH C C+ G C +C Y D P
Sbjct: 248 DLQVGGR-CKCNGHAS---RCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATAR 303
Query: 1086 ---DCVPCDCDLRGTSGDACNLEQGLCGCVEETGAC-PCKENVFGPQCNECREGTF---A 1138
C+ C C+ N+E G C C+ N G C+ CREG +
Sbjct: 304 ESHACLACSCNGHARRC-RFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPG 362
Query: 1139 LRADNPLGCSPCFC 1152
+ C C C
Sbjct: 363 RALSDRRACRACDC 376
>gi|164414431 netrin G1 isoform 1 [Homo sapiens]
Length = 539
Score = 171 bits (433), Expect = 1e-41
Identities = 136/454 (29%), Positives = 197/454 (43%), Gaps = 92/454 (20%)
Query: 40 TCGEKGPEMFCKLVEHVPGRPVR-NPQCRICDGNSANPRE-------RHPISHAIDGTNN 91
TCG+ PE FC + G P N +C A+P E RHP +
Sbjct: 71 TCGDP-PETFCAM-----GNPYMCNNECDASTPELAHPPELMFDFEGRHP--------ST 116
Query: 92 WWQSPSIQNGREYHWVTITLDLRQVFQVAYVIIKAANAPRPGNWILERSLD-GTTFSPWQ 150
+WQS + + + V ITL + ++ I+ + RP ILE+SLD G T+ P+Q
Sbjct: 117 FWQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQ 176
Query: 151 YYAVSDSECLSRYNITPRRGPP-TYRADDEVICTSYYSRLVPLEHGEIHTSLING----- 204
YYA ++CL +++ P+ + E+ICT YS IH + +
Sbjct: 177 YYA---TDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFA 233
Query: 205 ----RPSAD-----DLSPKLLEFTSARYIRLRLQRIRTLNADLMTLSHREPKELDPIVTR 255
R A D + KL +F + +R+RL +R ++ +D +
Sbjct: 234 GPRLRNMASLYGQLDTTKKLRDFFTVTDLRIRL--LRPAVGEIF---------VDELHLA 282
Query: 256 RYYYSIKDISVGGMCICYGHASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRP 315
RY+Y+I DI V G C C HA+ C +D + KL C+CEHNT G C +C Y +PW P
Sbjct: 283 RYFYAISDIKVRGRCKCNLHATVCVYDNS--KLTCECEHNTTGPDCGKCKKNYQGRPWSP 340
Query: 316 GTV-----SSGNTCEA-------CNCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCIN 363
G+ + NTC C C + C Y + LNT +C++
Sbjct: 341 GSYLPIPKGTANTCIPSISSIGNCECFGHSNRCSYIDL-------LNTV-------ICVS 386
Query: 364 CLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQ 423
C NT G +CE C GY+R ++ C C C+P+GS+ C NG
Sbjct: 387 CKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRC----------NGS- 435
Query: 424 PGQCPCKEGYTGEKCDRCQLGYKDYPTCVSCGCN 457
G C CK G TG KCD C G + C C+
Sbjct: 436 -GFCECKTGTTGPKCDECLPGNSWHYGCQPNVCD 468
Score = 87.8 bits (216), Expect = 1e-16
Identities = 75/255 (29%), Positives = 98/255 (38%), Gaps = 54/255 (21%)
Query: 801 NFSPTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNPTVPGESC-VPCDCSGNVDPSE 859
N T + D ++ C+ C +G C +C Y G P PG +P + PS
Sbjct: 300 NLHATVCVYDNSKLTCE-CEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSI 358
Query: 860 AGHCDSVTGECLKCLGNTDGAHCERCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETG 919
S G C +C G H RC S + L T
Sbjct: 359 -----SSIGNC-ECFG-----HSNRC-------------------------SYIDLLNTV 382
Query: 920 LC-DCKPNVTGQQCDQCLHGYYG-----LDSGHGCRPCNCSVAGSVSDGCTDEGQCHCVP 973
+C CK N GQ C+ C GY+ LD + C C C+ GS+ D C G C C
Sbjct: 383 ICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNGSGFCECKT 442
Query: 974 GVAGKRCDRCAHG---FYAYQDGSCTPCDCPHTQN--TCDPETGECVCPPHTQGVKCEE- 1027
G G +CD C G Y Q C + H QN TC C+CP G+ CE+
Sbjct: 443 GTTGPKCDECLPGNSWHYGCQPNVCDN-ELLHCQNGGTCHNNV-RCLCPAAYTGILCEKL 500
Query: 1028 -CED-GHWGYDAEVG 1040
CE+ G G D+ G
Sbjct: 501 RCEEAGSCGSDSGQG 515
Score = 79.0 bits (193), Expect = 7e-14
Identities = 51/164 (31%), Positives = 69/164 (42%), Gaps = 28/164 (17%)
Query: 1403 CSCNNHSDTCDPNTGKCL-NCGDNTAGDHCDVCTSGYYGKV----------TGSASDC-- 1449
C CN H+ C + K C NT G C C Y G+ G+A+ C
Sbjct: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIP 356
Query: 1450 -----ALCAC-PHSPPASFSPTCVLEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQTP- 1502
C C HS S+ ++ + C +C G+HCE C Y+ N
Sbjct: 357 SISSIGNCECFGHSNRCSY-----IDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQL 411
Query: 1503 --GGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDECEP 1544
C +C CNP GS+H C+ SG C C+ G +G +CDEC P
Sbjct: 412 DDENVCIECYCNPLGSIHDRCNG-SGFCECKTGTTGPKCDECLP 454
Score = 74.3 bits (181), Expect = 2e-12
Identities = 68/261 (26%), Positives = 101/261 (38%), Gaps = 52/261 (19%)
Query: 902 CECHVKGSHSAVCHLETG--LCDCKPNVTGQQCDQCLHGYYGLDSGHGCRPCNCSVAGSV 959
C+C++ H+ VC + C+C+ N TG C +C Y G RP + +
Sbjct: 297 CKCNL---HATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQG-------RPWSPGSYLPI 346
Query: 960 SDGCTDEGQCHCVPGVAGKRCDRCAHGFYAYQDGSCTPCDCPHTQNTCDP----ETGECV 1015
G + C+P ++ S C+C N C T CV
Sbjct: 347 PKGTANT----CIPSIS-----------------SIGNCECFGHSNRCSYIDLLNTVICV 385
Query: 1016 -CPPHTQGVKCEECEDGHWG-----YDAEVGCQACNCSLVGSTHHRCDVVTGHCQCKSKF 1069
C +T+G CE C G++ D E C C C+ +GS H RC+ +G C+CK+
Sbjct: 386 SCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNG-SGFCECKTGT 444
Query: 1070 GGRACDQCSLGYRDFPDCVPCDCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQC 1129
G CD+C G C P CD + + + G G C C G C
Sbjct: 445 TGPKCDECLPGNSWHYGCQPNVCD-----NELLHCQNG--GTCHNNVRCLCPAAYTGILC 497
Query: 1130 NECR-EGTFALRADNPLGCSP 1149
+ R E + +D+ G P
Sbjct: 498 EKLRCEEAGSCGSDSGQGAPP 518
Score = 71.2 bits (173), Expect = 1e-11
Identities = 73/264 (27%), Positives = 104/264 (39%), Gaps = 44/264 (16%)
Query: 1309 DFMSVLSDIEYILIKASYGQ----GLQQSR----ISDISMEVGRKAEKLHPEEEVASLLE 1360
DF +V +D+ L++ + G+ L +R ISDI + GR LH V +
Sbjct: 255 DFFTV-TDLRIRLLRPAVGEIFVDELHLARYFYAISDIKVR-GRCKCNLHATVCVYDNSK 312
Query: 1361 -NCVCPPGTVGFSCQDCAPGYHRGKLPAGSDRG-PRPLVAPCVP-------CSCNNHSDT 1411
C C T G C C Y GS P+ C+P C C HS+
Sbjct: 313 LTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNR 372
Query: 1412 CDP----NTGKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALC-ACPHSPPASFSPTC 1466
C NT C++C NT G HC++C GY+ + D +C C +P S C
Sbjct: 373 CSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRC 432
Query: 1467 VLEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCD-----CNPHGSVHGDC 1521
G C+ C G G C+ C GN G CD C G+ H +
Sbjct: 433 NGSG----FCE-CKTGTTGPKCDECLP---GNSWHYGCQPNVCDNELLHCQNGGTCHNNV 484
Query: 1522 DRTSGQCVCRLGASGLRCDE--CE 1543
+C+C +G+ C++ CE
Sbjct: 485 -----RCLCPAAYTGILCEKLRCE 503
Score = 67.8 bits (164), Expect = 2e-10
Identities = 69/235 (29%), Positives = 87/235 (37%), Gaps = 39/235 (16%)
Query: 742 CECHGHAAEC---NVHGVCIACAHNTTGVHCEQCLPGFYGEP---------SRGTPGDCQ 789
C+C+ HA C N C C HNTTG C +C + G P +GT C
Sbjct: 297 CKCNLHATVCVYDNSKLTC-ECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCI 355
Query: 790 PCA-----CPLTIASNNFSPTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNPTVPGE 844
P C SN S LN V+C C G CE C GY+ N + +
Sbjct: 356 PSISSIGNCECFGHSNRCSYIDLLN---TVICVSCKHNTRGQHCELCRLGYFRNASAQLD 412
Query: 845 S---CVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCADG---FYGDAVTAKN 898
C+ C C N S C+ +G C +C T G C+ C G YG +
Sbjct: 413 DENVCIECYC--NPLGSIHDRCNG-SGFC-ECKTGTTGPKCDECLPGNSWHYGCQPNVCD 468
Query: 899 CRACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCL---HGYYGLDSGHGCRP 950
C G+ CH C C TG C++ G G DSG G P
Sbjct: 469 NELLHCQNGGT----CH-NNVRCLCPAAYTGILCEKLRCEEAGSCGSDSGQGAPP 518
Score = 65.9 bits (159), Expect = 6e-10
Identities = 53/184 (28%), Positives = 66/184 (35%), Gaps = 47/184 (25%)
Query: 327 CNCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYY-RPHK 385
C C+ A C YD S + C NT G +C C Y RP
Sbjct: 297 CKCNLHATVCVYDNSK-----------------LTCECEHNTTGPDCGKCKKNYQGRPWS 339
Query: 386 VSPYEDEP------CRPC-----NCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYT 434
Y P C P NC+ G + D L++ + CK
Sbjct: 340 PGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCSYIDLLNTVIC-------VSCKHNTR 392
Query: 435 GEKCDRCQLGY--------KDYPTCVSCGCNPVGSASDEPCTGP--CVCKENVEGKACDR 484
G+ C+ C+LGY D C+ C CNP+GS D C G C CK G CD
Sbjct: 393 GQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDR-CNGSGFCECKTGTTGPKCDE 451
Query: 485 CKPG 488
C PG
Sbjct: 452 CLPG 455
Score = 62.0 bits (149), Expect = 9e-09
Identities = 53/195 (27%), Positives = 70/195 (35%), Gaps = 51/195 (26%)
Query: 709 CECPQGYTGTSCESCLSGY---------YRVDGILFGGICQP-------CECHGHAAECN 752
CEC TG C C Y Y C P CEC GH+ C+
Sbjct: 315 CECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCS 374
Query: 753 VHG-----VCIACAHNTTGVHCEQCLPGFYGEPSRGTPGD--CQPCACPLTIASNNFSPT 805
+C++C HNT G HCE C G++ S + C C C N +
Sbjct: 375 YIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYC-------NPLGS 427
Query: 806 CHLNDGDEVVCDWCAPGYSGAWCERCADG---YYGNPTVPGESCVPCDCSGNVDPSEAGH 862
H C+ C G +G C+ C G +YG C NV +E H
Sbjct: 428 IHDRCNGSGFCE-CKTGTTGPKCDECLPGNSWHYG-------------CQPNVCDNELLH 473
Query: 863 CDSVTGEC---LKCL 874
C + G C ++CL
Sbjct: 474 CQN-GGTCHNNVRCL 487
Score = 38.9 bits (89), Expect = 0.079
Identities = 29/110 (26%), Positives = 44/110 (40%), Gaps = 33/110 (30%)
Query: 427 CPCKEGYTGEKCDRCQLGYKDYP---------------TCVSC-----GCNPVGSAS--- 463
C C+ TG C +C+ Y+ P TC+ C G ++
Sbjct: 315 CECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCS 374
Query: 464 --DEPCTGPCV-CKENVEGKACDRCKPGFY-----NLKEKNPRGCSECFC 505
D T CV CK N G+ C+ C+ G++ L ++N C EC+C
Sbjct: 375 YIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENV--CIECYC 422
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 167 bits (424), Expect = 1e-40
Identities = 148/437 (33%), Positives = 178/437 (40%), Gaps = 83/437 (18%)
Query: 709 CECPQGYTGTSCES-CLSGYYRVDGILFGGIC-QPCECHGHAAECNVHGVCIACAHNTTG 766
C CP G+TG C+S CL G+ FG C Q C C AA +V G C C TG
Sbjct: 1104 CLCPAGWTGDKCQSPCLRGW-------FGEACAQRCSCPPGAACHHVTGAC-RCPPGFTG 1155
Query: 767 VHCEQ-CLPGFYGEPSRGTPGDC-QPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYS 824
CEQ C PG +GE DC Q C CP +P CH G C CA GY
Sbjct: 1156 SGCEQACPPGSFGE-------DCAQMCQCP------GENPACHPATG---TCS-CAAGYH 1198
Query: 825 GAWCE-RCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCE 883
G C+ RC G YG PG + C C G CD+ TG C +C G C
Sbjct: 1199 GPSCQQRCPPGRYG----PGCEQL-CGCLNG------GSCDAATGAC-RCPTGFLGTDCN 1246
Query: 884 -RCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQ-CLHGYYG 941
C G +G T C C A C TG C C P G +C++ C +G
Sbjct: 1247 LTCPQGRFGPNCT----HVCGC----GQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFG 1298
Query: 942 LDSGHGCRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCD-RCAHGFYAYQDGSC-TPCD 999
+ H C+C G G C C G G+ C+ C G Y +C C
Sbjct: 1299 VGCEH---TCSCRNGGLCH---ASNGSCSCGLGWTGRHCELACPPGRYG---AACHLECS 1349
Query: 1000 CPHTQNTCDPETGECVCPPHTQGVKCEE-CEDGHWGYDAEVGCQA-CNCSLVGSTHHRCD 1057
C H +TC+P TG C C P G CE C G G GCQ C C CD
Sbjct: 1350 C-HNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHG----AGCQGLCWCQHGAP----CD 1400
Query: 1058 VVTGHCQCKSKFGGRACDQ-CSLGYRDFPDCVPCDCDLRGTSGDACNLEQGLCGCVE-ET 1115
++G C C + F G C++ C G CDCD G C+ GLC C +
Sbjct: 1401 PISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCD----GGAPCDPVTGLCLCPPGRS 1456
Query: 1116 GA---CPCKENVFGPQC 1129
GA C+ FGP C
Sbjct: 1457 GATCNLDCRRGQFGPSC 1473
Score = 167 bits (423), Expect = 1e-40
Identities = 158/557 (28%), Positives = 203/557 (36%), Gaps = 168/557 (30%)
Query: 709 CECPQGYTGTSCES-CLSGYYRVDGILFGGICQPCECHGHAAECNVHGVCIACAHNTTGV 767
C CP G TG CE+ C G + G+ IC C+ HAA C+ C G
Sbjct: 758 CRCPPGRTGEDCEADCPEGRW---GLGCQEICPACQ---HAARCDPETGACLCLPGFVGS 811
Query: 768 HCEQCLP-GFYGEPSRGTPGDCQP-CACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYSG 825
C+ P G+YG PS CQ C+C A++ CH G C CAPG++G
Sbjct: 812 RCQDVCPAGWYG-PS------CQTRCSC----ANDGH---CHPATGH---CS-CAPGWTG 853
Query: 826 AWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCER- 884
C+R D + P + PC+CS G CD+++G CL C G CE+
Sbjct: 854 FSCQRACDTGHWGP----DCSHPCNCSAG-----HGSCDAISGLCL-CEAGYVGPRCEQQ 903
Query: 885 CADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQ-CLHGYYGLD 943
C G +G + C+C H A C +G C C G C+ C G++GLD
Sbjct: 904 CPQGHFGPGCEQR----CQCQ----HGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLD 955
Query: 944 SGHGCR---------------------------PC-------NCSVAGSVSDGCTDE--- 966
C C NCS A + +G + +
Sbjct: 956 CRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVH 1015
Query: 967 GQCHCVPGVAGKRC----------DRCAHGFYAYQDGSCTP----CDCPH---------- 1002
GQCHC PG G C D C H G+C P C CP
Sbjct: 1016 GQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKE 1075
Query: 1003 -----------------TQNTCDPETGECVCPPHTQGVKCEE-CEDGHWGYDAEVGCQAC 1044
CDP TG C+CP G KC+ C G +G E Q C
Sbjct: 1076 CLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFG---EACAQRC 1132
Query: 1045 NCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQ-CSLGY------------RDFPDCVP-- 1089
+C + HH VTG C+C F G C+Q C G + P C P
Sbjct: 1133 SCPPGAACHH----VTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPAT 1188
Query: 1090 --CDCDLRGTSGDACNLE----------QGLCGCVE------ETGACPCKENVFGPQCN- 1130
C C G G +C + LCGC+ TGAC C G CN
Sbjct: 1189 GTCSC-AAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNL 1247
Query: 1131 ECREGTFALRADNPLGC 1147
C +G F + GC
Sbjct: 1248 TCPQGRFGPNCTHVCGC 1264
Score = 145 bits (366), Expect = 6e-34
Identities = 154/617 (24%), Positives = 201/617 (32%), Gaps = 199/617 (32%)
Query: 687 SVSLDIASSNAIDLVVAADVEHCECPQGYTGTSCES-CLSGYYR---------------- 729
S S + D V A C CP G +GT+CE C GYY
Sbjct: 565 SFSCSCQNGGTCDSVTGA----CRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCH 620
Query: 730 -------VDGILFGGIC--------------QPCEC-HGHAAECNVHGVCIACAHNTTGV 767
D L+G C + C+C H C+ +C G
Sbjct: 621 RLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGE 680
Query: 768 HCE-QCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYSGA 826
C+ +C G++G PG Q C CP+ +A ++ S C C G+ G
Sbjct: 681 RCQAECELGYFG------PGCWQACTCPVGVACDSVSGECGKR---------CPAGFQGE 725
Query: 827 WC-ERCADGYYGNPTVPGESC--VPC----------------DCSGNVDPSE-------- 859
C + C G +G SC PC DC +
Sbjct: 726 DCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEI 785
Query: 860 ------AGHCDSVTGECLKCLGNTDGAHCER-CADGFYGDAVTAKNCRACECHVKGSHSA 912
A CD TG CL CL G+ C+ C G+YG + + C C G
Sbjct: 786 CPACQHAARCDPETGACL-CLPGFVGSRCQDVCPAGWYGPSCQTR----CSCANDGH--- 837
Query: 913 VCHLETGLCDCKPNVTGQQCDQ-CLHGYYGLDSGHGCRPCNCSVAGSVSDGCTDEGQCHC 971
CH TG C C P TG C + C G++G D H PCNCS D + G C C
Sbjct: 838 -CHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSH---PCNCSAGHGSCDAIS--GLCLC 891
Query: 972 VPGVAGKRCDR----------------CAHGFYA-YQDGSCT------------------ 996
G G RC++ C HG + G+CT
Sbjct: 892 EAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGF 951
Query: 997 -PCDCPHTQN-----TCDPETGECVCPPHTQGVKC-EECEDGHWGYDAEVGC-------- 1041
DC N CD G C+CP +G +C E C +G++ C
Sbjct: 952 FGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASC 1011
Query: 1042 -------------------QACNCSLVGSTHHR---------CDVVTGHCQCKSKFGGRA 1073
QAC L G CD V+GHC C + G A
Sbjct: 1012 DPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLA 1071
Query: 1074 CDQCSLGYRDFPDCVPCDCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQC-NEC 1132
C++ +C+P D C L GLC TG C C G +C + C
Sbjct: 1072 CEK---------ECLPRDVRAGCRHSGGC-LNGGLCD--PHTGRCLCPAGWTGDKCQSPC 1119
Query: 1133 REGTFALRADNPLGCSP 1149
G F C P
Sbjct: 1120 LRGWFGEACAQRCSCPP 1136
Score = 145 bits (366), Expect = 6e-34
Identities = 141/502 (28%), Positives = 184/502 (36%), Gaps = 140/502 (27%)
Query: 709 CECPQGYTGTSCE-SCLSGYYRVDGILFGGICQP-CECHGHAAECNVHGVCIA------- 759
C CP G+ GT CE +C +G++ +D C+ C C AA V+G C+
Sbjct: 932 CTCPAGWRGTFCEHACPAGFFGLD-------CRSACNCTAGAACDAVNGSCLCPAGRRGP 984
Query: 760 -----CAHNTTGVHCEQ---CLPGFYGEPSRG----TPGDCQPC---ACPLTIASNNFSP 804
C +T G +C Q C G +P G PG P ACP + +N
Sbjct: 985 RCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRH 1044
Query: 805 TCHLNDGDEVVCD------WCAPGYSGAWCERCADGYYGNPTVPGESCVPCD----CSGN 854
+C +G CD C G++G CE+ C+P D C +
Sbjct: 1045 SCLCQNGG--TCDPVSGHCACPEGWAGLACEK--------------ECLPRDVRAGCRHS 1088
Query: 855 VDPSEAGHCDSVTGECLKCLGNTDGAHCER-CADGFYGDAVTAKNCRACECHVKGSHSAV 913
G CD TG CL C G C+ C G++G+A + C C A
Sbjct: 1089 GGCLNGGLCDPHTGRCL-CPAGWTGDKCQSPCLRGWFGEACAQR----CSC----PPGAA 1139
Query: 914 CHLETGLCDCKPNVTGQQCDQ-CLHGYYGLDSGHGCR-------------PCNCSVA--- 956
CH TG C C P TG C+Q C G +G D C+ C+C+
Sbjct: 1140 CHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHG 1199
Query: 957 ---------GSVSDGCTD-------------EGQCHCVPGVAGKRCD-RCAHGFYAYQDG 993
G GC G C C G G C+ C G +
Sbjct: 1200 PSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFG---P 1256
Query: 994 SCTP-CDCPHTQNTCDPETGECVCPPHTQGVKCEE-CEDGHWGYDAEVGCQ-ACNCSLVG 1050
+CT C C CDP TG C+CPP GV+CE C +G VGC+ C+C G
Sbjct: 1257 NCTHVCGCGQGA-ACDPVTGTCLCPPGRAGVRCERGCPQNRFG----VGCEHTCSCRNGG 1311
Query: 1051 STHHRCDVVTGHCQCKSKFGGRACDQCSLGYRDFPDCVPCDCDLRGTSGDACNLE---QG 1107
C G C C + GR C+ C P G G AC+LE
Sbjct: 1312 ----LCHASNGSCSCGLGWTGRHCELA---------CPP------GRYGAACHLECSCHN 1352
Query: 1108 LCGCVEETGACPCKENVFGPQC 1129
C TG C C +G C
Sbjct: 1353 NSTCEPATGTCRCGPGFYGQAC 1374
Score = 144 bits (364), Expect = 1e-33
Identities = 130/468 (27%), Positives = 178/468 (38%), Gaps = 84/468 (17%)
Query: 706 VEHCECPQGYTGTSC-ESCLSGYYRVDGILFGGICQ-PCECHGHAAECNVHGVCIACAHN 763
++ C+CP+G+TG C E+C FG C C C +V G C C
Sbjct: 537 LDGCDCPEGWTGLICNETCPPD-------TFGKNCSFSCSCQNGGTCDSVTGAC-RCPPG 588
Query: 764 TTGVHCEQ-CLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPG 822
+G +CE C G+YG+ R + C C + C C PG
Sbjct: 589 VSGTNCEDGCPKGYYGKHCR------KKCNCANRGRCHRLYGAC-----------LCDPG 631
Query: 823 YSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHC 882
G +C + P E C C V P CD G C C G C
Sbjct: 632 LYGRFCHLTCPPWAFGPGCSEE----CQC---VQPHTQS-CDKRDGSC-SCKAGFRGERC 682
Query: 883 E-RCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCD--CKPNVTGQQCDQ-CLHG 938
+ C G++G +AC C V C +G C C G+ C Q C G
Sbjct: 683 QAECELGYFGPGCW----QACTCPV----GVACDSVSGECGKRCPAGFQGEDCGQECPVG 734
Query: 939 YYGLDSGHGCRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCDR-CAHGFYAYQDGSCTP 997
+G++ +CS G+ G T GQC C PG G+ C+ C G + P
Sbjct: 735 TFGVNCSS-----SCSCGGAPCHGVT--GQCRCPPGRTGEDCEADCPEGRWGLGCQEICP 787
Query: 998 CDCPHTQNTCDPETGECVCPPHTQGVKCEE-CEDGHWGYDAEVGCQACNCSLVGSTHHRC 1056
C H CDPETG C+C P G +C++ C G +G + C N C
Sbjct: 788 A-CQHAAR-CDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCAN-------DGHC 838
Query: 1057 DVVTGHCQCKSKFGGRACDQ-CSLGYRDFPDCV-PCDCDLRGTSGDACNLEQGLCGCVEE 1114
TGHC C + G +C + C G+ PDC PC+C S DA
Sbjct: 839 HPATGHCSCAPGWTGFSCQRACDTGHWG-PDCSHPCNCSAGHGSCDAI------------ 885
Query: 1115 TGACPCKENVFGPQC-NECREGTFALRADNPLGCS-PCFCSGLSHLCS 1160
+G C C+ GP+C +C +G F + C C +S C+
Sbjct: 886 SGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACT 933
Score = 119 bits (298), Expect = 5e-26
Identities = 114/389 (29%), Positives = 140/389 (35%), Gaps = 100/389 (25%)
Query: 709 CECPQGYTGTSCE-SCLSGYYRVDGILFGGICQPCECHGHAAECNVHGVCIACAHNTTGV 767
C CP G+TG+ CE +C G + D Q C+C G C+ +CA G
Sbjct: 1147 CRCPPGFTGSGCEQACPPGSFGED------CAQMCQCPGENPACHPATGTCSCAAGYHGP 1200
Query: 768 HCEQ-CLPGFYGEPSRG-----TPGDCQP----CACP---------LTIASNNFSPTC-H 807
C+Q C PG YG G C C CP LT F P C H
Sbjct: 1201 SCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTH 1260
Query: 808 L-NDGDEVVCD------WCAPGYSGAWCER-CADGYYGNPTVPGESCVPCDCSGNVDPSE 859
+ G CD C PG +G CER C +G C
Sbjct: 1261 VCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFG-----------VGCEHTCSCRN 1309
Query: 860 AGHCDSVTGECLKCLGNTDGAHCE-RCADGFYGDAVTAKNCRACECHVKGSHSAVCHLET 918
G C + G C LG T G HCE C G YG A + C CH +++ C T
Sbjct: 1310 GGLCHASNGSCSCGLGWT-GRHCELACPPGRYGAACHLE----CSCH----NNSTCEPAT 1360
Query: 919 GLCDCKPNVTGQQCDQ-CLHGYYGL--------DSGHGCRP----CNCSVA--------- 956
G C C P GQ C+ C G++G G C P C C
Sbjct: 1361 GTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERG 1420
Query: 957 ---GSVSDGCTDE-------------GQCHCVPGVAGKRCDR-CAHGFYAYQDGSCT-PC 998
GS +GC G C C PG +G C+ C G + SCT C
Sbjct: 1421 CEPGSFGEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFG---PSCTLHC 1477
Query: 999 DCPHTQNTCDPETGECVCPPHTQGVKCEE 1027
DC + CDP +G+C C G C E
Sbjct: 1478 DCGGGAD-CDPVSGQCHCVDGYMGPTCRE 1505
Score = 79.7 bits (195), Expect = 4e-14
Identities = 130/553 (23%), Positives = 168/553 (30%), Gaps = 150/553 (27%)
Query: 702 VAADVEHCECPQGYT----GTSCES---CLSGYYR-VDGILFGGICQPCECHG------- 746
V + CEC GY G +CE C +G + G L C CH
Sbjct: 261 VVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGAD 320
Query: 747 ------------HAAECNVHGVCIACAHNTTGVHCEQCLPGFYGEPSRGTPGDCQPCA-- 792
++ E N G C+H + G C C G+ + + T D CA
Sbjct: 321 GRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCT-CPRGYELDTDQRTCIDVDDCADS 379
Query: 793 --CPLTIASNNFSPTCHLNDGDEVVCDWCAPGYSGAWCE---RCADGYYGNP----TVPG 843
C +N C G + D C CE CA G + G
Sbjct: 380 PCCQQVCTNNPGGYECGCYAGYRLSADGCG-------CEDVDECASSRGGCEHHCTNLAG 432
Query: 844 ESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGA----HCERCADG----FYGDAVT 895
C+ + G C + + G H D F D V
Sbjct: 433 SFQCSCEAGYRLHEDRRG-CSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVG 491
Query: 896 AKNCRACECHVKGSHSA----VCHLETGLCDCKPNVTGQQCDQCLHG---YYGLDSGHGC 948
A E ++G H+ VC ++ DC CD C +G GLD
Sbjct: 492 ADEE---EAELRGEHTLTEKFVCLDDSFGHDCSLT-----CDDCRNGGTCLLGLDG---- 539
Query: 949 RPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCDRCAHGFYAYQDGSCTPCDCPHTQNTCD 1008
C+C G C + C P GK C C C + TCD
Sbjct: 540 --CDCP-EGWTGLICNET----CPPDTFGKNCS--------------FSCSCQNG-GTCD 577
Query: 1009 PETGECVCPPHTQGVKCEE-CEDGHWGYDAEVGCQACN---------------------- 1045
TG C CPP G CE+ C G++G C N
Sbjct: 578 SVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFC 637
Query: 1046 ----------------CSLVGSTHHRCDVVTGHCQCKSKFGGRACD-QCSLGYRDFPDC- 1087
C V CD G C CK+ F G C +C LGY P C
Sbjct: 638 HLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFG-PGCW 696
Query: 1088 VPCDCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQC-NECREGTFALRADNPLG 1146
C C + G AC+ G CG C G C EC GTF + +
Sbjct: 697 QACTCPV----GVACDSVSGECG-------KRCPAGFQGEDCGQECPVGTFGVNCSSSCS 745
Query: 1147 CSPCFCSGLSHLC 1159
C C G++ C
Sbjct: 746 CGGAPCHGVTGQC 758
Score = 75.9 bits (185), Expect = 6e-13
Identities = 72/237 (30%), Positives = 87/237 (36%), Gaps = 64/237 (27%)
Query: 1359 LENCVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGK 1418
L+ C CP G G C + P GK + S CSC N TCD TG
Sbjct: 537 LDGCDCPEGWTGLICNETCPPDTFGKNCSFS-------------CSCQN-GGTCDSVTGA 582
Query: 1419 CLNCGDNTAGDHC-DVCTSGYYGKVTGSASDCA----------LCACPHS---------- 1457
C C +G +C D C GYYGK +CA C C
Sbjct: 583 C-RCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTC 641
Query: 1458 PPASFSPTCVLE----GDHDFRCD------ACLLGYEGKHCE-RCSSSYYGNPQTPGGSC 1506
PP +F P C E H CD +C G+ G+ C+ C Y+G G
Sbjct: 642 PPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFG-----PGCW 696
Query: 1507 QKCDCNPHGSVHGDCDRTSGQC--VCRLGASGLRC-DECEPRHILMETDCVSCDDEC 1560
Q C C P G CD SG+C C G G C EC + T V+C C
Sbjct: 697 QACTC-PVGVA---CDSVSGECGKRCPAGFQGEDCGQECP-----VGTFGVNCSSSC 744
Score = 75.1 bits (183), Expect = 1e-12
Identities = 58/186 (31%), Positives = 78/186 (41%), Gaps = 39/186 (20%)
Query: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKCLN 1421
C CPPG G C+ P G+ G C H+ CDP TG CL
Sbjct: 758 CRCPPGRTGEDCEADCP---EGRWGLGCQE----------ICPACQHAARCDPETGACL- 803
Query: 1422 CGDNTAGDHC-DVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGDHDFRCDACL 1480
C G C DVC +G+YG + CA H PA+ C +C
Sbjct: 804 CLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDG--HCHPATG------------HC-SCA 848
Query: 1481 LGYEGKHCER-CSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLRC 1539
G+ G C+R C + ++G P S C+C+ + HG CD SG C+C G G RC
Sbjct: 849 PGWTGFSCQRACDTGHWG----PDCS-HPCNCS---AGHGSCDAISGLCLCEAGYVGPRC 900
Query: 1540 DECEPR 1545
++ P+
Sbjct: 901 EQQCPQ 906
Score = 72.0 bits (175), Expect = 8e-12
Identities = 61/217 (28%), Positives = 79/217 (36%), Gaps = 57/217 (26%)
Query: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKCLN 1421
C+C PG VG CQD P G P+ R CSC N C P TG C +
Sbjct: 802 CLCLPGFVGSRCQDVCPAGWYG--PSCQTR-----------CSCANDGH-CHPATGHC-S 846
Query: 1422 CGDNTAGDHCD-VCTSGYYGKVTGSASDCA-----------LCACP----------HSPP 1459
C G C C +G++G +C+ LC C P
Sbjct: 847 CAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQ 906
Query: 1460 ASFSPTCV--LEGDHDFRCD------ACLLGYEGKHCER-CSSSYYGNPQTPGGSCQK-C 1509
F P C + H CD C G+ G CE C + ++G C+ C
Sbjct: 907 GHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGL------DCRSAC 960
Query: 1510 DCNPHGSVHGDCDRTSGQCVCRLGASGLRCDECEPRH 1546
+C + CD +G C+C G G RC E P H
Sbjct: 961 NCTAGAA----CDAVNGSCLCPAGRRGPRCAETCPAH 993
Score = 67.0 bits (162), Expect = 3e-10
Identities = 67/252 (26%), Positives = 86/252 (34%), Gaps = 79/252 (31%)
Query: 1361 NCVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKCL 1420
+C C PG GFSCQ H G P S PC+C+ +CD +G CL
Sbjct: 844 HCSCAPGWTGFSCQRACDTGHWG--PDCSH-----------PCNCSAGHGSCDAISGLCL 890
Query: 1421 NCGDNTAGDHCDV-CTSGYYGKVTGSASDC----------ALCACP---------HSPPA 1460
C G C+ C G++G C C CP H+ PA
Sbjct: 891 -CEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPA 949
Query: 1461 SF-------SPTCVLEGDHDFRCDACLL--GYEGKHC-ERCSSSYYGNPQTPGGSC-QKC 1509
F + C D +CL G G C E C + YG+ + +C
Sbjct: 950 GFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGA 1009
Query: 1510 DCNP-HGSVH--------------------------------GDCDRTSGQCVCRLGASG 1536
C+P HG H G CD SG C C G +G
Sbjct: 1010 SCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAG 1069
Query: 1537 LRCD-ECEPRHI 1547
L C+ EC PR +
Sbjct: 1070 LACEKECLPRDV 1081
Score = 67.0 bits (162), Expect = 3e-10
Identities = 70/239 (29%), Positives = 85/239 (35%), Gaps = 63/239 (26%)
Query: 1362 CVCPPGTVGFSCQDCAPGYH--------------------RGKLPAGSDRGPRPLVAPCV 1401
C+CPPG G C+ P G G R C
Sbjct: 1277 CLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACP 1336
Query: 1402 P----------CSCNNHSDTCDPNTGKCLNCGDNTAGDHCD-VCTSGYYGKVTGSASDCA 1450
P CSC+N+S TC+P TG C CG G C+ C G++G A
Sbjct: 1337 PGRYGAACHLECSCHNNS-TCEPATGTC-RCGPGFYGQACEHPCPPGFHG-----AGCQG 1389
Query: 1451 LCACPHSPPAS-FSPTCVLE-GDHDFRCD-ACLLGYEGKHCER---CSSSYYGNPQT--- 1501
LC C H P S C+ G H C+ C G G+ C + C +P T
Sbjct: 1390 LCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLC 1449
Query: 1502 ---PGGSCQKC--DCN-----PHGSVH------GDCDRTSGQCVCRLGASGLRCDECEP 1544
PG S C DC P ++H DCD SGQC C G G C E P
Sbjct: 1450 LCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGGP 1508
Score = 65.5 bits (158), Expect = 8e-10
Identities = 68/266 (25%), Positives = 92/266 (34%), Gaps = 86/266 (32%)
Query: 1361 NCVCPPGTVGFSCQ-DCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKC 1419
+C CP G G +C+ +C P R + A C + CDP+TG+C
Sbjct: 1060 HCACPEGWAGLACEKECLP---------------RDVRAGCRHSGGCLNGGLCDPHTGRC 1104
Query: 1420 LNCGDNTAGDHCDV-CTSGYYGKVTGSASDC----------ALCACPHS----------P 1458
L C GD C C G++G+ C C CP P
Sbjct: 1105 L-CPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACP 1163
Query: 1459 PASFSPTCV----LEGDHDFRCDA-----CLLGYEGKHCE-RCSSSYYGNPQTP------ 1502
P SF C G++ A C GY G C+ RC YG
Sbjct: 1164 PGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLN 1223
Query: 1503 GGSCQ------KC-------DCN---PHGSVHGDC------------DRTSGQCVCRLGA 1534
GGSC +C DCN P G +C D +G C+C G
Sbjct: 1224 GGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGR 1283
Query: 1535 SGLRCDECEPRHILMETDCVSCDDEC 1560
+G+RC+ P++ V C+ C
Sbjct: 1284 AGVRCERGCPQNRF----GVGCEHTC 1305
Score = 65.1 bits (157), Expect = 1e-09
Identities = 69/268 (25%), Positives = 96/268 (35%), Gaps = 53/268 (19%)
Query: 263 DISVGGMCICYGHASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGN 322
D GG C+ CP T C +T G++C+ C + +G
Sbjct: 526 DCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSC-----------SCQNGG 574
Query: 323 TCE----AC---------NCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTM 369
TC+ AC NC + YY + K+ N R G C+ C
Sbjct: 575 TCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACL-CDPGLY 633
Query: 370 GINCE-TCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCP 428
G C TC P P E C+ C++ S K+ G C
Sbjct: 634 GRFCHLTC-----PPWAFGPGCSEECQ-------------CVQPHTQSC---DKRDGSCS 672
Query: 429 CKEGYTGEKCD-RCQLGYKDYPTCVSCGCNPVGSASDEPCTGPC--VCKENVEGKAC-DR 484
CK G+ GE+C C+LGY +C C PVG A D +G C C +G+ C
Sbjct: 673 CKAGFRGERCQAECELGYFGPGCWQACTC-PVGVACDS-VSGECGKRCPAGFQGEDCGQE 730
Query: 485 CKPGFYNLKEKNPRGCSECFCFGVSDVC 512
C G + + + C C GV+ C
Sbjct: 731 CPVGTFGVNCSSSCSCGGAPCHGVTGQC 758
Score = 61.6 bits (148), Expect = 1e-08
Identities = 64/216 (29%), Positives = 73/216 (33%), Gaps = 58/216 (26%)
Query: 1362 CVCPPGTVGFSC-QDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKCL 1420
C CPPG G C Q C PG G D C C + C P TG C
Sbjct: 1147 CRCPPGFTGSGCEQACPPGSF------GEDCAQM--------CQCPGENPACHPATGTC- 1191
Query: 1421 NCGDNTAGDHCDV-CTSGYYGK--------VTGSASDCAL--CACPHS----------PP 1459
+C G C C G YG + G + D A C CP P
Sbjct: 1192 SCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQ 1251
Query: 1460 ASFSPTC--VLEGDHDFRCDA------CLLGYEGKHCERCSSSYYGNPQTPGG-SCQK-C 1509
F P C V CD C G G CER G PQ G C+ C
Sbjct: 1252 GRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCER------GCPQNRFGVGCEHTC 1305
Query: 1510 DCNPHGSVHGDCDRTSGQCVCRLGASGLRCD-ECEP 1544
C G H ++G C C LG +G C+ C P
Sbjct: 1306 SCRNGGLCHA----SNGSCSCGLGWTGRHCELACPP 1337
Score = 58.5 bits (140), Expect = 1e-07
Identities = 66/267 (24%), Positives = 90/267 (33%), Gaps = 38/267 (14%)
Query: 267 GGMCICYGHASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPW---RPGTVSSGNT 323
G C A CP T + C + GE C + C + P GT S
Sbjct: 1137 GAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAG 1196
Query: 324 CEACNCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCE-TCIDGYYR 382
+C + Y + LN G C C +G +C TC G +
Sbjct: 1197 YHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGAC-RCPTGFLGTDCNLTCPQGRFG 1255
Query: 383 P---HKVSPYEDEPCRP----CNCDPVGSLSSVCIKD----------DLHSDLHNG---- 421
P H + C P C C P G C + + NG
Sbjct: 1256 PNCTHVCGCGQGAACDPVTGTCLCPP-GRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCH 1314
Query: 422 KQPGQCPCKEGYTGEKCD-RCQLGYKDYPTCVSCGCNPVGSASDEPCTGPCVCKENVEGK 480
G C C G+TG C+ C G + C C+ +++ EP TG C C G+
Sbjct: 1315 ASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCH--NNSTCEPATGTCRCGPGFYGQ 1372
Query: 481 ACDR-CKPGFYNLKEKNPRGCSE-CFC 505
AC+ C PGF+ GC C+C
Sbjct: 1373 ACEHPCPPGFHG------AGCQGLCWC 1393
Score = 53.9 bits (128), Expect = 2e-06
Identities = 60/249 (24%), Positives = 87/249 (34%), Gaps = 55/249 (22%)
Query: 289 QCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCE-ACNCHNKAKDC----------- 336
QC+C GE C CP + W G C+ A C + C
Sbjct: 757 QCRCPPGRTGEDCEADCP---EGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRC 813
Query: 337 -------YYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCE-TCIDGYYRPHKVSP 388
+Y S + N G C +C G +C+ C G++ P
Sbjct: 814 QDVCPAGWYGPSCQTRCSCANDGHCHPATGHC-SCAPGWTGFSCQRACDTGHWGP----- 867
Query: 389 YEDEPCRPCNCDP-VGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCD-RCQLGYK 446
+ PCNC GS ++ G C C+ GY G +C+ +C G+
Sbjct: 868 ---DCSHPCNCSAGHGSCDAI---------------SGLCLCEAGYVGPRCEQQCPQGHF 909
Query: 447 DYPTCVS-CGCNPVGSASDEPCTGPCVCKENVEGKACDR-CKPGFYNLKEKNPRGCSE-C 503
P C C C G+A D +G C C G C+ C GF+ L ++ C+
Sbjct: 910 G-PGCEQRCQCQH-GAACDH-VSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGA 966
Query: 504 FCFGVSDVC 512
C V+ C
Sbjct: 967 ACDAVNGSC 975
Score = 52.0 bits (123), Expect = 9e-06
Identities = 60/236 (25%), Positives = 85/236 (36%), Gaps = 49/236 (20%)
Query: 290 CQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKSL 349
C C+ G C+ CP PW G S E C C + +S K+ S
Sbjct: 626 CLCDPGLYGRFCHLTCP-----PWAFGPGCS----EECQCVQP-----HTQSCDKRDGSC 671
Query: 350 NTAGQFRG------------GGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPC-RP 396
+ FRG G C +G+ C++ + G + ++ E C +
Sbjct: 672 SCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDS-VSGECGKRCPAGFQGEDCGQE 730
Query: 397 CNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCD------RCQLGYKDYPT 450
C PVG+ C GQC C G TGE C+ R LG ++
Sbjct: 731 C---PVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQE--I 785
Query: 451 CVSCGCNPVGSASDEPCTGPCVCKENVEGKAC-DRCKPGFYNLKEKNPRGCSECFC 505
C +C +A +P TG C+C G C D C G+Y P + C C
Sbjct: 786 CPAC----QHAARCDPETGACLCLPGFVGSRCQDVCPAGWY-----GPSCQTRCSC 832
Score = 48.9 bits (115), Expect = 8e-05
Identities = 79/314 (25%), Positives = 105/314 (33%), Gaps = 76/314 (24%)
Query: 934 QCLHGYYGLDSGHGCRPCNCSVAGSVSDGCTDEGQ---CHCVPGVAGKRC----DRCAHG 986
+C G+ GC CS + G G CHC PG G RC D C
Sbjct: 109 RCCRGWMQQPDEEGCLSAECSASLCFHGGRCVPGSAQPCHCPPGFQGPRCQYDVDEC--- 165
Query: 987 FYAYQDGSCTPCDCPHTQNTC--DPETGECVCPP----HTQGVKC---EECEDGHWGYDA 1037
+G C Q+ C P + C C P HT C C G+
Sbjct: 166 --RTHNGGC--------QHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNG---- 211
Query: 1038 EVGCQACNCSLVGSTHHRCDVVTG--------HC----QCKSKFG----------GRACD 1075
GCQ +C + T HRC G HC C ++ G G A
Sbjct: 212 --GCQH-HCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARC 268
Query: 1076 QCSLGYRDFPDCVPCDCDLRGTSGDACNLEQGLCGCVEETGACPC------KENVFGPQC 1129
+C +GY+ D C+ A L Q GC+ G+ C + G QC
Sbjct: 269 ECHVGYQLAADGKACE----DVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQC 324
Query: 1130 NECREGTFALRADNPLGCS-PCFCSGLSHLCS-----ELEDYVRTPVTLG--SDQPLLRV 1181
N GCS C + LC+ EL+ RT + + +D P +
Sbjct: 325 YRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQ 384
Query: 1182 VSQSNLRGTTEGVY 1195
V +N G G Y
Sbjct: 385 VCTNNPGGYECGCY 398
Score = 48.9 bits (115), Expect = 8e-05
Identities = 56/239 (23%), Positives = 75/239 (31%), Gaps = 55/239 (23%)
Query: 290 CQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKSL 349
C+C G CN CP P N C C A
Sbjct: 1234 CRCPTGFLGTDCNLTCPQGRFGP---------NCTHVCGCGQGA--------ACDPVTGT 1276
Query: 350 NTAGQFRGGGVCIN-CLQNTMGINCETCIDGYYRPHKVSPYEDEPCRP----CNCD---- 400
R G C C QN G+ CE H S C C+C
Sbjct: 1277 CLCPPGRAGVRCERGCPQNRFGVGCE---------HTCSCRNGGLCHASNGSCSCGLGWT 1327
Query: 401 --------PVGSLSSVC-IKDDLHSDLHNGKQPGQCPCKEGYTGEKCDR-CQLGYKDYPT 450
P G + C ++ H++ G C C G+ G+ C+ C G+
Sbjct: 1328 GRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGC 1387
Query: 451 CVSCGCNPVGSASDEPCTGPCVCKENVEGKACDR-CKPGFYNLKEKNPRGCSE-CFCFG 507
C C A +P +G C+C G C+R C+PG + GC + C C G
Sbjct: 1388 QGLCWCQH--GAPCDPISGRCLCPAGFHGHFCERGCEPGSFG------EGCHQRCDCDG 1438
Score = 48.1 bits (113), Expect = 1e-04
Identities = 89/348 (25%), Positives = 114/348 (32%), Gaps = 89/348 (25%)
Query: 776 FYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYSGAWCERCADGY 835
F+G R PG QPC CP P C D DE ++G RC +
Sbjct: 134 FHG--GRCVPGSAQPCHCPPGFQ----GPRCQY-DVDE------CRTHNGGCQHRCVN-- 178
Query: 836 YGNPTVPGESCVPCDCSGNVDPSEAGHCDSVT-----------GECL-KCLGNTDGAHCE 883
PG C+C P H DS T G C C+ T H
Sbjct: 179 -----TPGSYL--CECK----PGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRC 227
Query: 884 RCADGFYGDAVTAKNCRACEC-HVKGSHSAVCHLETGLCDCKPNV------TGQQC---D 933
+C GF R C + GS C + GL C+ +V G+ C D
Sbjct: 228 QCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVD 287
Query: 934 QCLHGY----YGLDSGHGCRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCDR----CAH 985
+C G +G + G C C + D QC+ + C+ C+H
Sbjct: 288 ECAAGLAQCAHGCLNTQGSFKCVCHAGYELG---ADGRQCYRIEMEIVNSCEANNGGCSH 344
Query: 986 GFYAYQDGSCTPCDCPH------TQNTCDPETGECVCPPHTQGVKCEECEDGHWGYDAEV 1039
G G C CP Q TC + +C P Q V C + GY E
Sbjct: 345 GCSHTSAGPL--CTCPRGYELDTDQRTC-IDVDDCADSPCCQQV----CTNNPGGY--EC 395
Query: 1040 GCQA--------CNCSLV-------GSTHHRCDVVTGHCQCKSKFGGR 1072
GC A C C V G H C + G QC + G R
Sbjct: 396 GCYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYR 443
Score = 47.8 bits (112), Expect = 2e-04
Identities = 66/260 (25%), Positives = 85/260 (32%), Gaps = 76/260 (29%)
Query: 265 SVGGMCICYGH------ASSCPWDETTK--KLQCQCEHNT-CGESCNRC-CPGYHQQPWR 314
++ G+C+C CP + +CQC+H C C CP WR
Sbjct: 884 AISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPA----GWR 939
Query: 315 PGTVSS--------GNTCE-ACNCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCL 365
GT G C ACNC A A L AG+ RG C
Sbjct: 940 -GTFCEHACPAGFFGLDCRSACNCTAGAA------CDAVNGSCLCPAGR-RGPRCAETCP 991
Query: 366 QNTMGINCE---TCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGK 422
+T G NC C +G +CDPV
Sbjct: 992 AHTYGHNCSQACACFNG-----------------ASCDPVH------------------- 1015
Query: 423 QPGQCPCKEGYTGEKC-DRCQLGYKDYPTCVSCGCNPVGSASDEPCTGPCVCKENVEGKA 481
GQC C G+ G C C G SC C G+ +P +G C C E G A
Sbjct: 1016 --GQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTC--DPVSGHCACPEGWAGLA 1071
Query: 482 CDR-CKPGFYNLKEKNPRGC 500
C++ C P ++ GC
Sbjct: 1072 CEKECLPRDVRAGCRHSGGC 1091
Score = 43.1 bits (100), Expect = 0.004
Identities = 29/90 (32%), Positives = 37/90 (41%), Gaps = 9/90 (10%)
Query: 1461 SFSPTCVLEGDHDFRCDACLLGYEGKHCERCSSSYYGN----PQTPGGSCQ-KCDCNPHG 1515
SF C L D CLLG +G C + N P T G +C C C G
Sbjct: 515 SFGHDCSLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGG 574
Query: 1516 SVHGDCDRTSGQCVCRLGASGLRCDECEPR 1545
+ CD +G C C G SG C++ P+
Sbjct: 575 T----CDSVTGACRCPPGVSGTNCEDGCPK 600
Score = 35.0 bits (79), Expect = 1.1
Identities = 50/179 (27%), Positives = 63/179 (35%), Gaps = 49/179 (27%)
Query: 288 LQCQCEHNTCGESCN---RCCPGYHQQ----PWRPGTVSSGNTCEA-CNCHNKAKDCYYD 339
L+C C +N+ E RC PG++ Q P PG +G C+ C C + A
Sbjct: 1346 LECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAG--CQGLCWCQHGAP----- 1398
Query: 340 ESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINC-ETC-IDGYYRPHKVSPYEDEPCRP- 396
+ L AG F G C + G C + C DG PC P
Sbjct: 1399 -CDPISGRCLCPAG-FHGHFCERGCEPGSFGEGCHQRCDCDG-----------GAPCDPV 1445
Query: 397 ---CNCDPVGSLSSVCIKD----------DLHSDLHNGKQ----PGQCPCKEGYTGEKC 438
C C P G + C D LH D G GQC C +GY G C
Sbjct: 1446 TGLCLCPP-GRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTC 1503
>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
Length = 1044
Score = 165 bits (417), Expect = 7e-40
Identities = 158/541 (29%), Positives = 197/541 (36%), Gaps = 140/541 (25%)
Query: 709 CECPQGYTGTSCES-CLSGYYRVDGILFGGICQ-PCECHGHAAECNVHGVCIACAHNTTG 766
C C G+ G CE C G + G CQ PC+C H A C+ CA TG
Sbjct: 161 CVCAAGFRGWRCEELCAPGTH-------GKGCQLPCQCR-HGASCDPRAGECLCAPGYTG 212
Query: 767 VHCEQ-CLPGFYGE--------PSRGT----PGDCQ--------PCA--CPLTIASNNFS 803
V+CE+ C PG +G + GT G+C CA CP N S
Sbjct: 213 VYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQPCPPGTFGQNCS 272
Query: 804 PTCHLNDGDEVVCDW------CAPGYSGAWC-ERCADGYYGNPTVPGESCVPCDCSGNVD 856
C + G + CD C GY G C E C G +G CS + D
Sbjct: 273 QDCPCHHGGQ--CDHVTGQCHCTAGYMGDRCQEECPFGSFG-----------FQCSQHCD 319
Query: 857 PSEAGHCDSVTGECLKCLGNTDGAHCER--CADGFYGDAVTAKNCRACECHVKGSHSAVC 914
G C TG C +C G C+ C +G +G T C C + S C
Sbjct: 320 CHNGGQCSPTTGAC-ECEPGYKGPRCQERLCPEGLHGPGCTLP----CPCDADNTIS--C 372
Query: 915 HLETGLCDCKPNVTGQQCDQ-CLHGYYGLDSGHGCR-PCNCSVAG---SVSDGCTDEGQC 969
H TG C C+P +G C++ C GYYG GC+ PC C S++ GCT
Sbjct: 373 HPVTGACTCQPGWSGHHCNESCPVGYYG----DGCQLPCTCQNGADCHSITGGCT----- 423
Query: 970 HCVPGVAGKRCD-RCAHGFYAYQDGSCTPCDCPHTQNTCDPETGECVCPPHTQGVKCE-E 1027
C PG G+ C CA G Y S C+ TC P G C C QG+ C
Sbjct: 424 -CAPGFMGEVCAVSCAAGTYGPNCSSICSCN---NGGTCSPVDGSCTCKEGWQGLDCTLP 479
Query: 1028 CEDGHWGYDAEVGCQ-----AC-----------------------------NCSLVGSTH 1053
C G WG + C AC NCS
Sbjct: 480 CPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCS 539
Query: 1054 HR--CDVVTGHCQCKSKFGGRACDQCSLGYRDFPDC-VPCDCDLRGTSGDACNLEQGLCG 1110
H CD VTGHC C + + G CD R P+C V C C+ G+
Sbjct: 540 HADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGS------------- 586
Query: 1111 CVEETGACPCKENVFGPQCNE-CREGTFALRADNPLGCSPCF-----CSGLSHLCSELED 1164
C E G+C C GP C C G + P C C C +S +C L
Sbjct: 587 CSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQP--CPLCVHSSRPCHHISGICECLPG 644
Query: 1165 Y 1165
+
Sbjct: 645 F 645
Score = 159 bits (402), Expect = 4e-38
Identities = 143/498 (28%), Positives = 178/498 (35%), Gaps = 115/498 (23%)
Query: 709 CECPQGYTGTSC-ESCLSGYYRVDGILFGGIC-QPCECHGHAAECNVHGVCIACAHNTTG 766
C C GY G C E C G FG C Q C+CH G C C G
Sbjct: 290 CHCTAGYMGDRCQEECPFGS-------FGFQCSQHCDCHNGGQCSPTTGAC-ECEPGYKG 341
Query: 767 VHCEQ--CLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYS 824
C++ C G +G PG PC C A N S CH G C C PG+S
Sbjct: 342 PRCQERLCPEGLHG------PGCTLPCPCD---ADNTIS--CHPVTG---ACT-CQPGWS 386
Query: 825 GAWC-ERCADGYYGNPTVPGESC-VPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHC 882
G C E C GYYG + C +PC C D C S+TG C G
Sbjct: 387 GHHCNESCPVGYYG------DGCQLPCTCQNGAD------CHSITGGCTCAPGFMGEVCA 434
Query: 883 ERCADGFYGDAVTAKNCRA-CECHVKGSHSAVCHLETGLCDCKPNVTGQQCD-QCLHGYY 940
CA G YG NC + C C+ G+ S V G C CK G C C G +
Sbjct: 435 VSCAAGTYGP-----NCSSICSCNNGGTCSPV----DGSCTCKEGWQGLDCTLPCPSGTW 485
Query: 941 GLDSGHGCRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCDR-CAHGFYAYQDGSCTP-C 998
GL+ C N + + +G C C PG G C+ C G + +C+ C
Sbjct: 486 GLNCNESCTCANGAACSPI------DGSCSCTPGWLGDTCELPCPDGTFGL---NCSEHC 536
Query: 999 DCPHTQNTCDPETGECVCPPHTQGVKCEE-CEDGHWGYDAEVGCQACN------------ 1045
DC H CDP TG C C G++C+ C G WG + V C N
Sbjct: 537 DCSHADG-CDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSCE 595
Query: 1046 --------------------------CSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSL 1079
C L + C ++G C+C F G C+Q
Sbjct: 596 CAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCA 655
Query: 1080 GYRDFPDCVP-CDCDLRGTSGDACNLEQGLCGC----VEETGACPCKENVFGPQC---NE 1131
G DC C C GT C+ G C C + + + C +GP C
Sbjct: 656 GGYFGQDCAQLCSCANNGT----CSPIDGSCQCFPGWIGKDCSQACPPGFWGPACFHACS 711
Query: 1132 CREGTFALRADNPLGCSP 1149
C G D C+P
Sbjct: 712 CHNGASCSAEDGACHCTP 729
Score = 149 bits (375), Expect = 5e-35
Identities = 111/328 (33%), Positives = 148/328 (45%), Gaps = 61/328 (18%)
Query: 708 HCECPQGYTGTSCES-CLSGYYRVDGILFGGICQ-PCECHGHAAECNVHGVCIACAHNTT 765
HC C G+TG C+S C G + G C C C + C+ CA
Sbjct: 550 HCCCLAGWTGIRCDSTCPPGRW-------GPNCSVSCSCE-NGGSCSPEDGSCECAPGFR 601
Query: 766 GVHCEQ-CLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYS 824
G C++ C PGFYG G QPC PL + S S CH G +C+ C PG+S
Sbjct: 602 GPLCQRICPPGFYGH------GCAQPC--PLCVHS---SRPCHHISG---ICE-CLPGFS 646
Query: 825 GAWCER-CADGYYGNPTVPGESCVP-CDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHC 882
GA C + CA GY+G + C C C+ N G C + G C +C G C
Sbjct: 647 GALCNQVCAGGYFG------QDCAQLCSCANN------GTCSPIDGSC-QCFPGWIGKDC 693
Query: 883 ER-CADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQ-CLHGYY 940
+ C GF+G A AC CH + A C E G C C P TG C Q C ++
Sbjct: 694 SQACPPGFWGPACF----HACSCH----NGASCSAEDGACHCTPGWTGLFCTQRCPAAFF 745
Query: 941 GLDSGHGCRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCD-RCAHGFYAYQDGSCTPCD 999
G D G C+ N + +S G+C C G G+ C+ RCA G + Y G C+
Sbjct: 746 GKDCGRVCQCQNGASCDHIS------GKCTCRTGFTGQHCEQRCAPGTFGY--GCQQLCE 797
Query: 1000 CPHTQNTCDPETGECVCPPHTQGVKCEE 1027
C + +TCD TG C C P +G++C++
Sbjct: 798 CMNN-STCDHVTGTCYCSPGFKGIRCDQ 824
Score = 148 bits (374), Expect = 7e-35
Identities = 122/381 (32%), Positives = 164/381 (43%), Gaps = 71/381 (18%)
Query: 709 CECPQGYTGTSCE-SCLSGYYRVDGILFGGIC-QPCECHGHAAECN-VHGVCIACAHNTT 765
C C G+ G +CE C G FG C + C+C HA C+ V G C C T
Sbjct: 508 CSCTPGWLGDTCELPCPDG-------TFGLNCSEHCDC-SHADGCDPVTGHC-CCLAGWT 558
Query: 766 GVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYSG 825
G+ C+ P P R P C+C +C DG C+ CAPG+ G
Sbjct: 559 GIRCDSTCP-----PGRWGPNCSVSCSC-------ENGGSCSPEDGS---CE-CAPGFRG 602
Query: 826 AWCER-CADGYYGNPTVPGESCVPCD-CSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCE 883
C+R C G+YG+ PC C + P C ++G C +CL GA C
Sbjct: 603 PLCQRICPPGFYGHGCAQ-----PCPLCVHSSRP-----CHHISGIC-ECLPGFSGALCN 651
Query: 884 R-CADGFYGDAVTAKNC-RACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQ-CLHGYY 940
+ CA G++G ++C + C C G+ S + G C C P G+ C Q C G++
Sbjct: 652 QVCAGGYFG-----QDCAQLCSCANNGTCSPI----DGSCQCFPGWIGKDCSQACPPGFW 702
Query: 941 GLDSGHGCRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRC-DRCAHGFYAYQDGSCTPCD 999
G H C +C S S ++G CHC PG G C RC F+ G C
Sbjct: 703 GPACFHAC---SCHNGASCS---AEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRV--CQ 754
Query: 1000 CPHTQNTCDPETGECVCPPHTQGVKCEE-CEDGHWGYDAEVGCQACNCSLVGSTHHRCDV 1058
C + + CD +G+C C G CE+ C G +GY + C+ N S CD
Sbjct: 755 CQNGAS-CDHISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQLCECMNNST-------CDH 806
Query: 1059 VTGHCQCKSKFGGRACDQCSL 1079
VTG C C F G CDQ +L
Sbjct: 807 VTGTCYCSPGFKGIRCDQAAL 827
Score = 137 bits (345), Expect = 2e-31
Identities = 126/434 (29%), Positives = 159/434 (36%), Gaps = 110/434 (25%)
Query: 771 QCLPGFYGEPSRGTPGD-CQPCACPLTIASNNFSP-TCHLNDGDEVVCDWCAPGYSGAWC 828
QC PG+Y GD C P + SP TCH C PG+ G C
Sbjct: 87 QCCPGYYES------GDFCIPLCTEECVHGRCVSPDTCH-----------CEPGWGGPDC 129
Query: 829 ERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCER-CAD 887
D + P CS C+ +TG C+ C G CE CA
Sbjct: 130 SSGCDSDHWGP----------HCSNRCQCQNGALCNPITGACV-CAAGFRGWRCEELCAP 178
Query: 888 GFYGDAVTAKNCR-ACECH---------------------------VKGSHSA------- 912
G +G K C+ C+C GSH A
Sbjct: 179 GTHG-----KGCQLPCQCRHGASCDPRAGECLCAPGYTGVYCEELCPPGSHGAHCELRCP 233
Query: 913 -----VCHLETGLCDCKPNVTGQQCDQ-CLHGYYGLDSGHGCRPCNCSVAGSVSDGCTDE 966
CH TG C C P TG C Q C G +G + C PC+ G D T
Sbjct: 234 CQNGGTCHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDC-PCH---HGGQCDHVT-- 287
Query: 967 GQCHCVPGVAGKRC-DRCAHGFYAYQDGSCTP-CDCPHTQNTCDPETGECVCPPHTQGVK 1024
GQCHC G G RC + C G + +Q C+ CDC H C P TG C C P +G +
Sbjct: 288 GQCHCTAGYMGDRCQEECPFGSFGFQ---CSQHCDC-HNGGQCSPTTGACECEPGYKGPR 343
Query: 1025 CEE--CEDGHWGYDAEVGCQ-ACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQ-CSLG 1080
C+E C +G G GC C C + C VTG C C+ + G C++ C +G
Sbjct: 344 CQERLCPEGLHG----PGCTLPCPCDADNTI--SCHPVTGACTCQPGWSGHHCNESCPVG 397
Query: 1081 YRDFPDCVPCDCDLRGTSGDACNLEQGLCGC----VEETGACPCKENVFGPQCN---ECR 1133
Y +PC C +G C+ G C C + E A C +GP C+ C
Sbjct: 398 YYGDGCQLPCTCQ----NGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCN 453
Query: 1134 EGTFALRADNPLGC 1147
G D C
Sbjct: 454 NGGTCSPVDGSCTC 467
Score = 108 bits (269), Expect = 1e-22
Identities = 90/297 (30%), Positives = 113/297 (38%), Gaps = 78/297 (26%)
Query: 921 CDCKPNVTGQQCDQ-CLHGYYGLDSGHGCRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKR 979
C C+P G C C ++G + C+ N ++ ++ G C C G G R
Sbjct: 118 CHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPIT------GACVCAAGFRGWR 171
Query: 980 CDR-CAHGFYAYQDGSCTPCDCPHTQNTCDPETGECVCPPHTQGVKCEE-CEDGHWGYDA 1037
C+ CA G + G PC C H + CDP GEC+C P GV CEE C G G
Sbjct: 172 CEELCAPGTHG--KGCQLPCQCRHGAS-CDPRAGECLCAPGYTGVYCEELCPPGSHGAHC 228
Query: 1038 EVGC---------------------------QAC-------NCSLVGSTHH--RCDVVTG 1061
E+ C Q C NCS HH +CD VTG
Sbjct: 229 ELRCPCQNGGTCHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTG 288
Query: 1062 HCQCKSKFGGRAC-DQCSLGYRDFPDCVPCDCDLRGTSGDACNLEQGLCGCVEETGACPC 1120
C C + + G C ++C G F CDC G C TGAC C
Sbjct: 289 QCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQ-------------CSPTTGACEC 335
Query: 1121 KENVFGPQCNE--CREGTFA--------LRADNPLGCSP----CFCS-GLS-HLCSE 1161
+ GP+C E C EG ADN + C P C C G S H C+E
Sbjct: 336 EPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNE 392
Score = 77.4 bits (189), Expect = 2e-13
Identities = 63/211 (29%), Positives = 82/211 (38%), Gaps = 56/211 (26%)
Query: 1362 CVCPPGTVGFSCQD-CAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKCL 1420
CVC G G+ C++ CAPG H +G + +PC C H +CDP G+CL
Sbjct: 161 CVCAAGFRGWRCEELCAPGTH--------GKGCQ------LPCQCR-HGASCDPRAGECL 205
Query: 1421 NCGDNTAGDHCD-VCTSGYYGKVTGSASDC----------ALCACPHS----------PP 1459
C G +C+ +C G +G C CACP PP
Sbjct: 206 -CAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQPCPP 264
Query: 1460 ASFSPTCVLEGD--HDFRCDA------CLLGYEGKHC-ERCSSSYYGNPQTPGGSCQKCD 1510
+F C + H +CD C GY G C E C +G + Q CD
Sbjct: 265 GTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCS-----QHCD 319
Query: 1511 CNPHGSVHGDCDRTSGQCVCRLGASGLRCDE 1541
C+ G C T+G C C G G RC E
Sbjct: 320 CHNGGQ----CSPTTGACECEPGYKGPRCQE 346
Score = 72.0 bits (175), Expect = 8e-12
Identities = 77/287 (26%), Positives = 105/287 (36%), Gaps = 54/287 (18%)
Query: 269 MCICYGHASSCPWDETTKKLQCQCEHNTCGESCNR------CCPGYH----QQPWRPGTV 318
+C H C +L CQC H G SC+ C PGY ++ PG
Sbjct: 175 LCAPGTHGKGC-------QLPCQCRH---GASCDPRAGECLCAPGYTGVYCEELCPPG-- 222
Query: 319 SSGNTCEA-CNCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCIN-CLQNTMGINCET- 375
S G CE C C N C++ G VC C T G NC
Sbjct: 223 SHGAHCELRCPCQNGGT-CHHITGECACPPGWT-------GAVCAQPCPPGTFGQNCSQD 274
Query: 376 --------CIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQ---- 423
C + H + Y + C+ C P GS C + H D HNG Q
Sbjct: 275 CPCHHGGQCDHVTGQCHCTAGYMGDRCQE-EC-PFGSFGFQCSQ---HCDCHNGGQCSPT 329
Query: 424 PGQCPCKEGYTGEKCDR--CQLGYKDYPTCVSCGCNPVGSASDEPCTGPCVCKENVEGKA 481
G C C+ GY G +C C G + C C+ + S P TG C C+ G
Sbjct: 330 TGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHH 389
Query: 482 C-DRCKPGFYNLKEKNPRGCSE-CFCFGVSDVCSSLSWPVGQVNSMS 526
C + C G+Y + P C C ++ C+ +G+V ++S
Sbjct: 390 CNESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVS 436
Score = 71.2 bits (173), Expect = 1e-11
Identities = 65/213 (30%), Positives = 80/213 (37%), Gaps = 60/213 (28%)
Query: 1362 CVCPPGTVGFSC-QDCAPGYHRGKLPAGSDRGPRPLVAPCVP-CSCNNHSDTCDPNTGKC 1419
C C PG G C Q CA GY G D C CSC N+ TC P G C
Sbjct: 639 CECLPGFSGALCNQVCAGGYF------GQD---------CAQLCSCANNG-TCSPIDGSC 682
Query: 1420 LNCGDNTAGDHCD-VCTSGYYGKVTGSASDC----------ALCACP----------HSP 1458
C G C C G++G A C C C P
Sbjct: 683 -QCFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQRCP 741
Query: 1459 PASFSPTC--VLEGDHDFRCD------ACLLGYEGKHCE-RCSSSYYGNPQTPGGSCQK- 1508
A F C V + + CD C G+ G+HCE RC+ P T G CQ+
Sbjct: 742 AAFFGKDCGRVCQCQNGASCDHISGKCTCRTGFTGQHCEQRCA------PGTFGYGCQQL 795
Query: 1509 CDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDE 1541
C+C + + CD +G C C G G+RCD+
Sbjct: 796 CECMNNST----CDHVTGTCYCSPGFKGIRCDQ 824
Score = 69.7 bits (169), Expect = 4e-11
Identities = 75/277 (27%), Positives = 97/277 (35%), Gaps = 64/277 (23%)
Query: 290 CQCEHNTCGESCNRCCP-GYHQQPWR-PGTVSSGNTCEA----CNCHN--KAKDCYYDES 341
C C+ G CN CP GY+ + P T +G C + C C + C +
Sbjct: 379 CTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCA 438
Query: 342 VAKQKKSLNTAGQFRGGGVC-------------------INCLQNTMGINCE---TCIDG 379
+ ++ GG C + C T G+NC TC +G
Sbjct: 439 AGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANG 498
Query: 380 YYRPHKVSPYEDEPCRPCNCDPVGSLSSVC----------IKDDLHSDLHN--GKQP--G 425
SP + C+C P G L C + H D + G P G
Sbjct: 499 A----ACSPIDGS----CSCTP-GWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTG 549
Query: 426 QCPCKEGYTGEKCDRCQLGYKDYPTC-VSCGCNPVGSASDEPCTGPCVCKENVEGKACDR 484
C C G+TG +CD + P C VSC C GS S E G C C G C R
Sbjct: 550 HCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPE--DGSCECAPGFRGPLCQR 607
Query: 485 -CKPGFYNLKEKNPRGCSECF-----CFGVSDVCSSL 515
C PGFY P C C C +S +C L
Sbjct: 608 ICPPGFYGHGCAQP--CPLCVHSSRPCHHISGICECL 642
Score = 64.3 bits (155), Expect = 2e-09
Identities = 65/231 (28%), Positives = 83/231 (35%), Gaps = 60/231 (25%)
Query: 1362 CVCPPGTVGFSCQDCAP-GYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKCL 1420
C C PG G C + P GY+ +PC+C N +D C TG C
Sbjct: 379 CTCQPGWSGHHCNESCPVGYYGDGCQ--------------LPCTCQNGAD-CHSITGGC- 422
Query: 1421 NCGDNTAGDHCDV-CTSGYYGKVTGSASDCALCACPHS---PPASFSPTCVLEGDHDFRC 1476
C G+ C V C +G YG S +C+C + P S TC EG C
Sbjct: 423 TCAPGFMGEVCAVSCAAGTYGPNCSS-----ICSCNNGGTCSPVDGSCTCK-EGWQGLDC 476
Query: 1477 DA-CLLGYEGKHCERCSSSYYGNPQTP-GGSC-------------------------QKC 1509
C G G +C + G +P GSC + C
Sbjct: 477 TLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHC 536
Query: 1510 DCNPHGSVHGD-CDRTSGQCVCRLGASGLRCDECEPRHILMETDCVSCDDE 1559
DC+ H D CD +G C C G +G+RCD P VSC E
Sbjct: 537 DCS-----HADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCE 582
Score = 63.5 bits (153), Expect = 3e-09
Identities = 60/197 (30%), Positives = 81/197 (41%), Gaps = 43/197 (21%)
Query: 1364 CPPGTVGFSCQD---CAPGYHRGKLPAGSDRGPRPLVAPC-VPC-------SCN-----N 1407
CP GT G +C + CA G + P L C +PC +C+ +
Sbjct: 480 CPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCS 539
Query: 1408 HSDTCDPNTGKCLNCGDNTAGDHCD-VCTSGYYGKVTGSASDCAL-CACPHSPPASFSPT 1465
H+D CDP TG C C G CD C G +G +C++ C+C + S SP
Sbjct: 540 HADGCDPVTGHCC-CLAGWTGIRCDSTCPPGRWGP------NCSVSCSCENG--GSCSP- 589
Query: 1466 CVLEGDHDFRCDACLLGYEGKHCER-CSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRT 1524
D C+ C G+ G C+R C +YG+ G Q C H S C
Sbjct: 590 ------EDGSCE-CAPGFRGPLCQRICPPGFYGH-----GCAQPCPLCVHSS--RPCHHI 635
Query: 1525 SGQCVCRLGASGLRCDE 1541
SG C C G SG C++
Sbjct: 636 SGICECLPGFSGALCNQ 652
Score = 56.6 bits (135), Expect = 4e-07
Identities = 55/233 (23%), Positives = 85/233 (36%), Gaps = 68/233 (29%)
Query: 269 MCICYGHASSCPWDETTKKLQCQCEHNTCGESCNRCCP-GYHQQPWRPGTVSSGNTCEAC 327
+C C + + P D + CQC G+ C++ CP G+ W P AC
Sbjct: 666 LCSCANNGTCSPIDGS-----CQCFPGWIGKDCSQACPPGF----WGPACF------HAC 710
Query: 328 NCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINC-ETCIDGYYRPHKV 386
+CHN A D G C +C G+ C + C ++
Sbjct: 711 SCHNGASCSAED-------------------GAC-HCTPGWTGLFCTQRCPAAFF----- 745
Query: 387 SPYEDEPC-RPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCD-RCQLG 444
+ C R C C S + G+C C+ G+TG+ C+ RC G
Sbjct: 746 ----GKDCGRVCQCQNGASCDHIS---------------GKCTCRTGFTGQHCEQRCAPG 786
Query: 445 YKDYPTCVSCGCNPVGSASDEPCTGPCVCKENVEGKACDRCKPGFYNLKEKNP 497
Y C C + +++ + TG C C +G CD+ ++E NP
Sbjct: 787 TFGYGCQQLCEC--MNNSTCDHVTGTCYCSPGFKGIRCDQAA---LMMEELNP 834
Score = 55.1 bits (131), Expect = 1e-06
Identities = 62/221 (28%), Positives = 74/221 (33%), Gaps = 59/221 (26%)
Query: 1357 SLLENCVCPPGTVGFSCQ-DCAPGYHRGKLPAGSDRGPRPLVAPCVP-CSCNNHSDTCDP 1414
S+ C C PG +G C CA G + GP C CSCNN TC P
Sbjct: 417 SITGGCTCAPGFMGEVCAVSCAAGTY----------GPN-----CSSICSCNN-GGTCSP 460
Query: 1415 NTGKCLNCGDNTAGDHCDV-CTSGYYGKVTGSASDCA----------LCACPHS------ 1457
G C C + G C + C SG +G + CA C+C
Sbjct: 461 VDGSC-TCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTC 519
Query: 1458 ----PPASFSPTCVLEGD--HDFRCD------ACLLGYEGKHCERCSSSYYGNPQTPGGS 1505
P +F C D H CD CL G+ G C+ P G +
Sbjct: 520 ELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCP-----PGRWGPN 574
Query: 1506 CQ-KCDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDE-CEP 1544
C C C GS C G C C G G C C P
Sbjct: 575 CSVSCSCENGGS----CSPEDGSCECAPGFRGPLCQRICPP 611
Score = 51.6 bits (122), Expect = 1e-05
Identities = 76/298 (25%), Positives = 101/298 (33%), Gaps = 74/298 (24%)
Query: 270 CICYGHASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNC 329
C C A+ P D + C C G++C CP GT N E C+C
Sbjct: 493 CTCANGAACSPIDGS-----CSCTPGWLGDTCELPCPD--------GTFGL-NCSEHCDC 538
Query: 330 HNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCE-TCIDGYYRPH---K 385
+ A C + V G C CL GI C+ TC G + P+
Sbjct: 539 SH-ADGC---DPVT--------------GHCC--CLAGWTGIRCDSTCPPGRWGPNCSVS 578
Query: 386 VSPYEDEPCRP----CNCDPVGSLSSVCIKDD----------------LHSDLHNGKQPG 425
S C P C C P G +C + +HS G
Sbjct: 579 CSCENGGSCSPEDGSCECAP-GFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISG 637
Query: 426 QCPCKEGYTGEKCDR-CQLGYKDYPTCVSCGCNPVGSASDEPCTGPCVCKENVEGKACDR 484
C C G++G C++ C GY C C G+ S P G C C GK C +
Sbjct: 638 ICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCS--PIDGSCQCFPGWIGKDCSQ 695
Query: 485 -CKPGFYNLKEKNPRGCSECFCFGVSDVCSSLSWPVGQVNSMSGWLVTDLISPRKIPS 541
C PGF+ P C C +S S G + GW T L ++ P+
Sbjct: 696 ACPPGFW-----GPACFHACSCHN----GASCSAEDGACHCTPGW--TGLFCTQRCPA 742
Score = 45.8 bits (107), Expect = 6e-04
Identities = 48/178 (26%), Positives = 67/178 (37%), Gaps = 53/178 (29%)
Query: 1376 CAPGYHRGK---LPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKCLNCGDNTAGDHCD 1432
C PGY+ +P ++ CV C + DTC +C G C
Sbjct: 88 CCPGYYESGDFCIPLCTEE--------CVHGRCVS-PDTC--------HCEPGWGGPDCS 130
Query: 1433 V-CTSGYYGKVTGSASDC---ALCACPHSPPASFSPTCVLEGDHDFRCDACLLGYEGKHC 1488
C S ++G + C ALC + CV C G+ G C
Sbjct: 131 SGCDSDHWGPHCSNRCQCQNGALCN-------PITGACV-----------CAAGFRGWRC 172
Query: 1489 ERCSSSYYGNPQTPGGSCQ-KCDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDE-CEP 1544
E + P T G CQ C C HG+ CD +G+C+C G +G+ C+E C P
Sbjct: 173 EELCA-----PGTHGKGCQLPCQCR-HGA---SCDPRAGECLCAPGYTGVYCEELCPP 221
Score = 41.6 bits (96), Expect = 0.012
Identities = 68/298 (22%), Positives = 91/298 (30%), Gaps = 89/298 (29%)
Query: 302 NRCCPGY--------------------------HQQP-WRPGTVSSG-----------NT 323
++CCPGY H +P W SSG N
Sbjct: 86 SQCCPGYYESGDFCIPLCTEECVHGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNR 145
Query: 324 CE------------ACNCHNKAKDCYYDESVA--KQKKSLNTAGQFRGGGVC------IN 363
C+ AC C + +E A K Q R G C
Sbjct: 146 CQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAGECL 205
Query: 364 CLQNTMGINC-ETCIDGYYRPH---KVSPYEDEPCR----PCNCDPVGSLSSVCIKD--- 412
C G+ C E C G + H + C C C P G +VC +
Sbjct: 206 CAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPP-GWTGAVCAQPCPP 264
Query: 413 -------DLHSDLHNGKQ----PGQCPCKEGYTGEKC-DRCQLGYKDYPTCVSCGCNPVG 460
H+G Q GQC C GY G++C + C G + C C+ G
Sbjct: 265 GTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGG 324
Query: 461 SASDEPCTGPCVCKENVEGKACDR--CKPGFYNLKEKNPRGC---SECFCFGVSDVCS 513
S P TG C C+ +G C C G + P C + C V+ C+
Sbjct: 325 QCS--PTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACT 380
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.420
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 125,287,905
Number of Sequences: 37866
Number of extensions: 6358023
Number of successful extensions: 31376
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 124
Number of HSP's successfully gapped in prelim test: 646
Number of HSP's that attempted gapping in prelim test: 17101
Number of HSP's gapped (non-prelim): 5975
length of query: 3075
length of database: 18,247,518
effective HSP length: 121
effective length of query: 2954
effective length of database: 13,665,732
effective search space: 40368572328
effective search space used: 40368572328
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.