Guide to the Human Genome
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Search of human proteins with 38488767

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|38488767 microtubule associated serine/threonine kinase
family member 4 isoform b [Homo sapiens]
         (250 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|38488767 microtubule associated serine/threonine kinase famil...   507   e-144
gi|112363080 microtubule associated serine/threonine kinase 2 [H...   112   2e-25
gi|148727255 microtubule associated serine/threonine kinase fami...    54   1e-07
gi|112421108 capicua homolog [Homo sapiens]                            47   2e-05
gi|163965366 nascent polypeptide-associated complex alpha subuni...    46   3e-05
gi|156104872 Ets2 repressor factor [Homo sapiens]                      46   3e-05
gi|149999378 inverted formin 2 isoform 2 [Homo sapiens]                45   5e-05
gi|149999380 inverted formin 2 isoform 1 [Homo sapiens]                45   5e-05
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]                     45   6e-05
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]                     45   6e-05
gi|66932986 filamin-binding LIM protein-1 isoform b [Homo sapiens]     45   6e-05
gi|66932982 filamin-binding LIM protein-1 isoform a [Homo sapiens]     45   6e-05
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    45   8e-05
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    45   8e-05
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    45   8e-05
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      44   1e-04
gi|160707881 formin 2 [Homo sapiens]                                   44   1e-04
gi|56549694 enabled homolog isoform a [Homo sapiens]                   43   2e-04
gi|39930375 enabled homolog isoform b [Homo sapiens]                   43   2e-04
gi|24431935 reticulon 4 isoform A [Homo sapiens]                       43   2e-04
gi|39812378 RAN binding protein 9 [Homo sapiens]                       42   4e-04
gi|169213924 PREDICTED: leucine rich repeat containing 68 [Homo ...    42   4e-04
gi|169214345 PREDICTED: leucine rich repeat containing 68 [Homo ...    42   4e-04
gi|169213302 PREDICTED: leucine rich repeat containing 68 [Homo ...    42   4e-04
gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Hom...    42   5e-04
gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Hom...    42   5e-04
gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo ...    42   5e-04
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      42   7e-04
gi|47519490 reticulon 4 isoform D [Homo sapiens]                       42   7e-04
gi|239754138 PREDICTED: hypothetical protein [Homo sapiens]            41   0.001

>gi|38488767 microtubule associated serine/threonine kinase family
           member 4 isoform b [Homo sapiens]
          Length = 250

 Score =  507 bits (1306), Expect = e-144
 Identities = 250/250 (100%), Positives = 250/250 (100%)

Query: 1   MGEKVSEAPEPVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSRE 60
           MGEKVSEAPEPVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSRE
Sbjct: 1   MGEKVSEAPEPVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSRE 60

Query: 61  HQPPPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDE 120
           HQPPPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDE
Sbjct: 61  HQPPPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDE 120

Query: 121 ELDHILSPPPMPFRKCSNPDVASGPGKSLKYKRQLSEDGRQLRRGSLGGALTGRYLLPNP 180
           ELDHILSPPPMPFRKCSNPDVASGPGKSLKYKRQLSEDGRQLRRGSLGGALTGRYLLPNP
Sbjct: 121 ELDHILSPPPMPFRKCSNPDVASGPGKSLKYKRQLSEDGRQLRRGSLGGALTGRYLLPNP 180

Query: 181 VAGQAWPASAETSNLVRMRSQALGQSAPSLTASLKELSLPRRGSLIDSQKWNCLVKRPVC 240
           VAGQAWPASAETSNLVRMRSQALGQSAPSLTASLKELSLPRRGSLIDSQKWNCLVKRPVC
Sbjct: 181 VAGQAWPASAETSNLVRMRSQALGQSAPSLTASLKELSLPRRGSLIDSQKWNCLVKRPVC 240

Query: 241 PNAGRTSPLG 250
           PNAGRTSPLG
Sbjct: 241 PNAGRTSPLG 250


>gi|112363080 microtubule associated serine/threonine kinase 2 [Homo
           sapiens]
          Length = 1798

 Score =  112 bits (281), Expect = 2e-25
 Identities = 84/207 (40%), Positives = 111/207 (53%), Gaps = 32/207 (15%)

Query: 62  QPPPPPPLGGTLGARAPAAWAPASVLLERGVLALPPP--LPGGAVPPAPRGSSASQEEQD 119
           +P PPPP     G +  A  + +          LPP    P G      R   A  E ++
Sbjct: 9   RPQPPPPDRREDGVQRAAELSQS----------LPPRRRAPPGRQRLEERTGPAGPEGKE 58

Query: 120 EELDHILSPPPMPFRKCSNPDVASGPGKSLKYKRQLSEDGRQLRRGSLGGALTGRYLLP- 178
           +++  +    P+ FRK SNPD+ S  GK +K +RQLS+D  +L RG+L  +L+G+ LLP 
Sbjct: 59  QDV--VTGVSPLLFRKLSNPDIFSSTGK-VKLQRQLSQDDCKLWRGNLASSLSGKQLLPL 115

Query: 179 -----NPVAGQAWPASAETSNLVRMRSQALGQSAPSLTASLKELSLPRRG---------S 224
                + V    W +S E SNLVRMR+Q+LGQSAPSLTA LKELSLPRRG         S
Sbjct: 116 SSSVHSSVGQVTWQSSGEASNLVRMRNQSLGQSAPSLTAGLKELSLPRRGSFCRTSNRKS 175

Query: 225 LIDSQKWNCLVKRPVCPNAGRT--SPL 249
           LI +   +  + RP  P  G T  SPL
Sbjct: 176 LIVTSSTSPTLPRPHSPLHGHTGNSPL 202


>gi|148727255 microtubule associated serine/threonine kinase family
           member 4 isoform a [Homo sapiens]
          Length = 2434

 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 27/36 (75%), Positives = 29/36 (80%), Gaps = 2/36 (5%)

Query: 215 KELSLPRRGSLIDSQKWNCLVKRPVCPNAGRTSPLG 250
           KELSLPRRGSLIDSQKWNCLVKR  C  + R S +G
Sbjct: 14  KELSLPRRGSLIDSQKWNCLVKR--CRTSNRKSLIG 47


>gi|112421108 capicua homolog [Homo sapiens]
          Length = 1608

 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 39/143 (27%), Positives = 53/143 (37%), Gaps = 3/143 (2%)

Query: 9   PEPVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPPP 68
           P+P      G+GS   +SA   ASS  +++   S GS T   +    G +     PPPP 
Sbjct: 518 PDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQGSTAGPLRPPPPG 577

Query: 69  LGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELDHILSP 128
            GG         + P      R      P   GG  PP P   +A        L  ++ P
Sbjct: 578 AGGPATPSKATRFLPMDPATFR---RKRPESVGGLEPPGPSVIAAPPSGGGNILQTLVLP 634

Query: 129 PPMPFRKCSNPDVASGPGKSLKY 151
           P    ++     V S P  SL Y
Sbjct: 635 PNKEEQEGGGARVPSAPAPSLAY 657



 Score = 30.0 bits (66), Expect = 2.0
 Identities = 33/120 (27%), Positives = 49/120 (40%), Gaps = 20/120 (16%)

Query: 24  PASALVAASSPGASS-AESSSGSETLSEEGEPGGFSREHQPPPPPPLGGTLGARAPAAWA 82
           P+ A   AS P AS+ ++  + S  ++ E  PGG        PP       GA  P +  
Sbjct: 55  PSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPERPP-------GATCPESPG 107

Query: 83  PASV----LLERGVLALPPPL---PGGAVPPAPRGSSASQEEQDEELDHILSPP---PMP 132
           P       ++E G    PPP         P  PR  S ++ + D+    I+SP    P+P
Sbjct: 108 PGPPHPLGVVESG--KGPPPTTEEEASGPPGEPRLDSETESDHDDAFLSIMSPEIQLPLP 165



 Score = 30.0 bits (66), Expect = 2.0
 Identities = 32/114 (28%), Positives = 45/114 (39%), Gaps = 15/114 (13%)

Query: 20   GSRTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPPPLGGTLGARAPA 79
            G   PA+A  A +SP  S+   ++GS T S         +  +P P  P       +  A
Sbjct: 1137 GPPAPATATPAPTSPFPSA---TAGSMTYSLVAP-----KAQRPSPKAP------QKVKA 1182

Query: 80   AWAPASV-LLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELDHILSPPPMP 132
            A A   V   E G    P P P   + P P     + E + E      +PPP+P
Sbjct: 1183 AIASIPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPLP 1236



 Score = 29.6 bits (65), Expect = 2.6
 Identities = 23/73 (31%), Positives = 29/73 (39%), Gaps = 19/73 (26%)

Query: 78   PAAWAPASVLLERGVLALPPPLP---GGAVPPAPRGSSASQEEQDEELDHILSPPPMPFR 134
            P A AP  V    G  A P P P   GG  P +P   S + +          + PP+P  
Sbjct: 1529 PGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQ----------AAPPLP-- 1576

Query: 135  KCSNPDVASGPGK 147
                P   SGPG+
Sbjct: 1577 ----PPPESGPGQ 1585



 Score = 28.5 bits (62), Expect = 5.8
 Identities = 22/71 (30%), Positives = 27/71 (38%), Gaps = 11/71 (15%)

Query: 6    SEAPEPVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETL---------SEEGEPGG 56
            +EAP PVP       +  PA     A  P  +S  S SG+            S  G+PG 
Sbjct: 1531 AEAPLPVPPPTGT--AAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESGPGQPGW 1588

Query: 57   FSREHQPPPPP 67
                   PPPP
Sbjct: 1589 EGAPQPSPPPP 1599



 Score = 27.7 bits (60), Expect = 9.8
 Identities = 24/65 (36%), Positives = 25/65 (38%), Gaps = 15/65 (23%)

Query: 63   PPPPPPLGGTLGARAPAAWA------------PASVLLERGVLALPP-PLPGGAVPPAPR 109
            PP PPP      A+ P   A            P   L  RG    PP P P  AV  AP 
Sbjct: 1247 PPLPPPAEERTSAKGPETMASKFPSSSSDWRVPGQGLENRGEPPTPPSPAPAPAV--APG 1304

Query: 110  GSSAS 114
            GSS S
Sbjct: 1305 GSSES 1309


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 62/256 (24%), Positives = 94/256 (36%), Gaps = 29/256 (11%)

Query: 11   PVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPP---- 66
            P P+G     + TP S     ++P    A ++  +   S +G P     +  P PP    
Sbjct: 1212 PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATP 1271

Query: 67   PPLGGTL------GARAPAAWAPASVLLERGVLALPP---PLPGGAVPPAPRGSSASQEE 117
            P L G L      GA  PA   P S   + G    PP   P P  A PP+P+GS  +   
Sbjct: 1272 PSLKGGLATPPHKGAPNPAVVTPPSP--KGGPATSPPKGAPTPPAATPPSPKGSPGTPPP 1329

Query: 118  QDEELDHILSPPP---MPFRKCSNPDVASGPGKSLKYKRQLSEDGRQLRRGSLGGALTGR 174
            +       ++PP     P    + P    GP      +           +G  G A+T  
Sbjct: 1330 KGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKG--GPAMTP- 1386

Query: 175  YLLPNPVAGQAWPA--SAETSNLVRMRSQALGQSAPSLTASLKELSLPRRGSLIDSQKWN 232
               P+P  G A P+     TS  V   S    + AP+   + +  + P +G L       
Sbjct: 1387 ---PSPKRGPAIPSPKGDPTSPAVIPLSP---KKAPATPVTREGAATPSKGDLTPPAVTP 1440

Query: 233  CLVKRPVCPNAGRTSP 248
              +K+    +A +  P
Sbjct: 1441 VSLKKAPATSAPKGGP 1456



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 35/132 (26%), Positives = 49/132 (37%), Gaps = 13/132 (9%)

Query: 11   PVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEGEPG------GFSREHQPP 64
            P P+G     + TP S     ++P    A +       S +G P       G S      
Sbjct: 980  PSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAAT 1039

Query: 65   PPPPLGGTLGARAP--AAWAPASVLLE-RGVLALPP----PLPGGAVPPAPRGSSASQEE 117
            PP P G       P  A   PA+ L   +G  A P     P P  A PP+P+G  A+   
Sbjct: 1040 PPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSP 1099

Query: 118  QDEELDHILSPP 129
            +   +    +PP
Sbjct: 1100 KGAPMPPAATPP 1111



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 36/132 (27%), Positives = 53/132 (40%), Gaps = 23/132 (17%)

Query: 4    KVSEAPEPVPRGCSGHGSRTPASALVA-ASSPGASSAESSSGSETLSEEGEPGGFSREHQ 62
            K S A  P P+G S   + TP S   + A++P    A ++  +   S +G P   S +  
Sbjct: 1020 KGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGA 1079

Query: 63   PPPPP-----PLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEE 117
            P PP      P GG      PA  +P              P+P  A PP+P+G  A+   
Sbjct: 1080 PTPPAATPPSPKGG------PATPSPKGA-----------PMPPAATPPSPKGGLATPPH 1122

Query: 118  QDEELDHILSPP 129
            +        +PP
Sbjct: 1123 KGAPTTPAATPP 1134



 Score = 35.8 bits (81), Expect = 0.036
 Identities = 43/182 (23%), Positives = 60/182 (32%), Gaps = 25/182 (13%)

Query: 11   PVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEG-----EPGGFSREHQPPP 65
            P P+G     + TP S     ++P    A ++  +   S +G      P G        P
Sbjct: 1097 PSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP 1156

Query: 66   PPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELDHI 125
            P P GG   A  P   AP +        A PP   GG   P+P+G+  +           
Sbjct: 1157 PSPKGGL--ATPPPKGAPTTPA------ATPPSPKGGLATPSPKGAPTTP---------- 1198

Query: 126  LSPPPMPFRKCSNPDVASGPGKSLKYKRQLSEDGRQLRRGSLGGALTGRYLLPNPVAGQA 185
             + PP P    + P     P  +       S  G        G   T     P+P  G A
Sbjct: 1199 AATPPSPKGGLATPSPKGAP--TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPA 1256

Query: 186  WP 187
             P
Sbjct: 1257 TP 1258



 Score = 34.3 bits (77), Expect = 0.10
 Identities = 39/138 (28%), Positives = 54/138 (39%), Gaps = 12/138 (8%)

Query: 5   VSEAPEPVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPP 64
           VS +P+   R  +  GS  P + +   SSP +    S     +LS +G     +  H P 
Sbjct: 799 VSVSPQ-TKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPT 857

Query: 65  PPPPLGGTLGARAPAAWAPASVLLERGVLALPP---PLPGGAVPPAPRGSSASQEEQDEE 121
           PP P     GA  P+A  P S    +GV  LPP   P P     P P+   A+   +   
Sbjct: 858 PPSP----KGAPTPSAVTPLS---PKGV-TLPPKETPTPSVVNLPFPKEGPATPAPKQAP 909

Query: 122 LDHILSPPPMPFRKCSNP 139
              + S  P   R    P
Sbjct: 910 ALSMTSSSPKKARATPAP 927



 Score = 33.1 bits (74), Expect = 0.23
 Identities = 32/129 (24%), Positives = 43/129 (33%), Gaps = 20/129 (15%)

Query: 4   KVSEAPEPVPRGCSGHGSRTPASALVAASSPGASS---AESSSGSETLSEEGEPGGFSRE 60
           K +  P  V       G  TPA     A S  +SS   A ++   + +     P G    
Sbjct: 883 KETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTP 942

Query: 61  HQPPPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDE 120
               PP P GG   A     WAP                P  A PP+P+G  A+   +  
Sbjct: 943 PAATPPSPKGGP--ATPSPKWAPT---------------PPAATPPSPKGGPATPSPKGA 985

Query: 121 ELDHILSPP 129
                 +PP
Sbjct: 986 PTPPAATPP 994


>gi|156104872 Ets2 repressor factor [Homo sapiens]
          Length = 548

 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 48/158 (30%), Positives = 64/158 (40%), Gaps = 30/158 (18%)

Query: 22  RTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPPPLGGTLGARAPA-- 79
           + P   +   + P  SSA SSS S +         F  + QPPP        G +A A  
Sbjct: 347 KCPLPPMAPETPPVPSSASSSSSSSS-------SPFKFKLQPPPLGRRQRAAGEKAVAGA 399

Query: 80  --AWAPASVLLE-RGVLALPPPLPGGAVPPAPRGSS--------ASQEEQDEELDHILSP 128
             +   A  L E  G LA PPP P   V P   G S        + ++E+D E+      
Sbjct: 400 DKSGGSAGGLAEGAGALAPPPPPPQIKVEPISEGESEEVEVTDISDEDEEDGEVFKTPRA 459

Query: 129 PPMPFRKCSNPDVASGPGKS------LKYKRQLSEDGR 160
           PP P      P+    PG S      L++KR+ SED R
Sbjct: 460 PPAP----PKPEPGEAPGASQCMPLKLRFKRRWSEDCR 493



 Score = 33.5 bits (75), Expect = 0.18
 Identities = 36/107 (33%), Positives = 46/107 (42%), Gaps = 11/107 (10%)

Query: 3   EKVSEAPEP-VPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSREH 61
           E +S   +P  P  CS   S    SA+VA      S ++ S G+   SE  EP G     
Sbjct: 151 EVLSPTEDPRSPPACSSSSSSL-FSAVVARRLGRGSVSDCSDGT---SELEEPLGEDPRA 206

Query: 62  QPPPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAP 108
           +PP PP LG   G   P A  P     + GV  + P   GG  P +P
Sbjct: 207 RPPGPPDLGAFRG--PPLARLPH----DPGVFRVYPRPRGGPEPLSP 247


>gi|149999378 inverted formin 2 isoform 2 [Homo sapiens]
          Length = 1240

 Score = 45.4 bits (106), Expect = 5e-05
 Identities = 43/151 (28%), Positives = 59/151 (39%), Gaps = 14/151 (9%)

Query: 7   EAPEPVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPP 66
           E  +P             + +++  S P A   ++S+          PG  S E  PPPP
Sbjct: 384 EGQQPAAAAACEPVDHAQSESILKVSQPRALEQQASTPPPPPPPPLLPGS-SAEPPPPPP 442

Query: 67  PPLGGTLGARAPAAWAPASVLLERGVLA-----LPPPLPGGA--VPPAP-----RGSSAS 114
           PP   ++GA+A     P   L   G +A     LPPPLPG    +PP P      G    
Sbjct: 443 PPPLPSVGAKALPTAPPPPPLPGLGAMAPPAPPLPPPLPGSCEFLPPPPPPLPGLGCPPP 502

Query: 115 QEEQDEELDHILSPPPMPFRKCS-NPDVASG 144
                  +     PPP P   C+ +P VA G
Sbjct: 503 PPPLLPGMGWGPPPPPPPLLPCTCSPPVAGG 533


>gi|149999380 inverted formin 2 isoform 1 [Homo sapiens]
          Length = 1249

 Score = 45.4 bits (106), Expect = 5e-05
 Identities = 43/151 (28%), Positives = 59/151 (39%), Gaps = 14/151 (9%)

Query: 7   EAPEPVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPP 66
           E  +P             + +++  S P A   ++S+          PG  S E  PPPP
Sbjct: 384 EGQQPAAAAACEPVDHAQSESILKVSQPRALEQQASTPPPPPPPPLLPGS-SAEPPPPPP 442

Query: 67  PPLGGTLGARAPAAWAPASVLLERGVLA-----LPPPLPGGA--VPPAP-----RGSSAS 114
           PP   ++GA+A     P   L   G +A     LPPPLPG    +PP P      G    
Sbjct: 443 PPPLPSVGAKALPTAPPPPPLPGLGAMAPPAPPLPPPLPGSCEFLPPPPPPLPGLGCPPP 502

Query: 115 QEEQDEELDHILSPPPMPFRKCS-NPDVASG 144
                  +     PPP P   C+ +P VA G
Sbjct: 503 PPPLLPGMGWGPPPPPPPLLPCTCSPPVAGG 533


>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
          Length = 1263

 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 35/103 (33%), Positives = 43/103 (41%), Gaps = 10/103 (9%)

Query: 63  PPPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGG-AVPPAPRGSSASQEEQDEE 121
           PPPPPPL G+ G   P    P     E G+   PPPLPGG  +PP P             
Sbjct: 679 PPPPPPLPGSAGIPPPPPPLPG----EAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPP 734

Query: 122 LDHILSPPPMPFRKCSNPDVASGPGKSLKYKRQLSEDGRQLRR 164
              +  PPP  F   + P +  G      YK ++     QLRR
Sbjct: 735 GMGMPPPPPFGFGVPAAPVLPFGLTPKKLYKPEV-----QLRR 772



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 35/113 (30%), Positives = 44/113 (38%), Gaps = 18/113 (15%)

Query: 37  SSAESSSGSETLSEEGEPGGFSREHQPPPPPPLGGTLGARAPAAWAPASVLLERGVLALP 96
           SS  S  G   +S    P   S +   PPPPPL   +G  +P++    + +        P
Sbjct: 619 SSPPSLPGGTAISP---PPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPP------P 669

Query: 97  PPLPGGA---VPPAPRGSSASQEEQDEELDHILSPPPMPFRKCSNPDVASGPG 146
           PPLPG A    PP P   SA        L      PP P      P +  GPG
Sbjct: 670 PPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPP------PPLPGGPG 716



 Score = 36.6 bits (83), Expect = 0.021
 Identities = 37/125 (29%), Positives = 44/125 (35%), Gaps = 28/125 (22%)

Query: 24  PASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPPPLGGTLGARAPAAWAP 83
           P S    A  P A      SG+  +     PG  +    PPPPPP         P    P
Sbjct: 564 PPSVPSRAPVPPAPPLPGDSGT-IIPPPPAPGDSTTPPPPPPPPP---------PPPPLP 613

Query: 84  ASVLLERGVLALPPPLPGGAV--PPAPRGSSASQEEQDEELDHILSPPPMPFRKCSNPDV 141
             V +       PP LPGG    PP P    A+          I  PPP+P      P  
Sbjct: 614 GGVCISS-----PPSLPGGTAISPPPPLSGDAT----------IPPPPPLP-EGVGIPSP 657

Query: 142 ASGPG 146
           +S PG
Sbjct: 658 SSLPG 662


>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
          Length = 1272

 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 35/103 (33%), Positives = 43/103 (41%), Gaps = 10/103 (9%)

Query: 63  PPPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGG-AVPPAPRGSSASQEEQDEE 121
           PPPPPPL G+ G   P    P     E G+   PPPLPGG  +PP P             
Sbjct: 688 PPPPPPLPGSAGIPPPPPPLPG----EAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPP 743

Query: 122 LDHILSPPPMPFRKCSNPDVASGPGKSLKYKRQLSEDGRQLRR 164
              +  PPP  F   + P +  G      YK ++     QLRR
Sbjct: 744 GMGMPPPPPFGFGVPAAPVLPFGLTPKKLYKPEV-----QLRR 781



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 35/113 (30%), Positives = 44/113 (38%), Gaps = 18/113 (15%)

Query: 37  SSAESSSGSETLSEEGEPGGFSREHQPPPPPPLGGTLGARAPAAWAPASVLLERGVLALP 96
           SS  S  G   +S    P   S +   PPPPPL   +G  +P++    + +        P
Sbjct: 628 SSPPSLPGGTAISP---PPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPP------P 678

Query: 97  PPLPGGA---VPPAPRGSSASQEEQDEELDHILSPPPMPFRKCSNPDVASGPG 146
           PPLPG A    PP P   SA        L      PP P      P +  GPG
Sbjct: 679 PPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPP------PPLPGGPG 725



 Score = 36.6 bits (83), Expect = 0.021
 Identities = 37/125 (29%), Positives = 44/125 (35%), Gaps = 28/125 (22%)

Query: 24  PASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPPPLGGTLGARAPAAWAP 83
           P S    A  P A      SG+  +     PG  +    PPPPPP         P    P
Sbjct: 573 PPSVPSRAPVPPAPPLPGDSGT-IIPPPPAPGDSTTPPPPPPPPP---------PPPPLP 622

Query: 84  ASVLLERGVLALPPPLPGGAV--PPAPRGSSASQEEQDEELDHILSPPPMPFRKCSNPDV 141
             V +       PP LPGG    PP P    A+          I  PPP+P      P  
Sbjct: 623 GGVCISS-----PPSLPGGTAISPPPPLSGDAT----------IPPPPPLP-EGVGIPSP 666

Query: 142 ASGPG 146
           +S PG
Sbjct: 667 SSLPG 671


>gi|66932986 filamin-binding LIM protein-1 isoform b [Homo sapiens]
          Length = 374

 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 42/144 (29%), Positives = 55/144 (38%), Gaps = 34/144 (23%)

Query: 7   EAPEPVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPP 66
           EAP P+         +TP + L    SP  +   +++       +   GG      PPPP
Sbjct: 44  EAPAPM---------KTPEAGLAGRPSPWTTPGRAAATVPAAPMQLFNGGC-----PPPP 89

Query: 67  PPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVP-----PAPRGSSASQEEQDEE 121
           P L G              VL +  +L  PPP P   +P     PAP G+S      D E
Sbjct: 90  PVLDGE------------DVLPDLDLLPPPPPPPPVLLPSEEEAPAPMGASLIA---DLE 134

Query: 122 LDHILSPPPMPFRKCSNPDVASGP 145
             H+  PPP P      P V  GP
Sbjct: 135 QLHLSPPPPPPQAPAEGPSVQPGP 158


>gi|66932982 filamin-binding LIM protein-1 isoform a [Homo sapiens]
          Length = 373

 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 42/144 (29%), Positives = 55/144 (38%), Gaps = 34/144 (23%)

Query: 7   EAPEPVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPP 66
           EAP P+         +TP + L    SP  +   +++       +   GG      PPPP
Sbjct: 44  EAPAPM---------KTPEAGLAGRPSPWTTPGRAAATVPAAPMQLFNGGC-----PPPP 89

Query: 67  PPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVP-----PAPRGSSASQEEQDEE 121
           P L G              VL +  +L  PPP P   +P     PAP G+S      D E
Sbjct: 90  PVLDGE------------DVLPDLDLLPPPPPPPPVLLPSEEEAPAPMGASLIA---DLE 134

Query: 122 LDHILSPPPMPFRKCSNPDVASGP 145
             H+  PPP P      P V  GP
Sbjct: 135 QLHLSPPPPPPQAPAEGPSVQPGP 158


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 44.7 bits (104), Expect = 8e-05
 Identities = 44/153 (28%), Positives = 57/153 (37%), Gaps = 16/153 (10%)

Query: 8   APEPVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPP 67
           AP P P       SR+P+S L      G SS+ +S+  E    +  P G +    PP   
Sbjct: 608 APGPPPPP-----SRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPP--- 659

Query: 68  PLGGTLGARAPAAWA--PASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEE---- 121
                L A  PAAW+  PA  L  RG    P P P    P +  G     E +  E    
Sbjct: 660 --DAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATP 717

Query: 122 LDHILSPPPMPFRKCSNPDVASGPGKSLKYKRQ 154
               L P P P          +G G S +  +Q
Sbjct: 718 APGALDPGPSPGTSGGKAAAGAGAGASSRSPKQ 750



 Score = 32.3 bits (72), Expect = 0.40
 Identities = 45/173 (26%), Positives = 61/173 (35%), Gaps = 21/173 (12%)

Query: 8   APEPVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPP 67
           AP   P   +G  SR PAS   A+     +    ++    +S  G   G +R   P P  
Sbjct: 74  APRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTR---PGPLG 130

Query: 68  PLGGTLGARAPAAWAPASVLLERGVLA------LPPPLPGGAVPPAPRGSSASQEEQDEE 121
             G  + A    A   A+   +R  L+         P PG   P   R S A+  E    
Sbjct: 131 QKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE---- 186

Query: 122 LDHILSPPPMPFRKCSNPDVASGPGKSLKYKRQLS---EDGRQLRRGSLGGAL 171
              +  P P P  +   P    GP KS+    + S         RR S GG L
Sbjct: 187 ---VGLPRPAPSARPRPP--TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGL 234



 Score = 29.6 bits (65), Expect = 2.6
 Identities = 29/89 (32%), Positives = 35/89 (39%), Gaps = 5/89 (5%)

Query: 21  SRTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPPPLGGTLGARA-PA 79
           S  P+  + A  SP AS   S S   T   +  P   +   Q PP PP    +   A P 
Sbjct: 441 SPPPSPPVQAPFSPPASPPVSPSA--TPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPP 498

Query: 80  AWAPASVLLERGVLALPPPL--PGGAVPP 106
             AP  +      LA PPP   P  A PP
Sbjct: 499 PQAPPPLAAPPLQLAKPPPQAPPALATPP 527


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 1124

 Score = 44.7 bits (104), Expect = 8e-05
 Identities = 44/153 (28%), Positives = 57/153 (37%), Gaps = 16/153 (10%)

Query: 8    APEPVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPP 67
            AP P P       SR+P+S L      G SS+ +S+  E    +  P G +    PP   
Sbjct: 877  APGPPPPP-----SRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPP--- 928

Query: 68   PLGGTLGARAPAAWA--PASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEE---- 121
                 L A  PAAW+  PA  L  RG    P P P    P +  G     E +  E    
Sbjct: 929  --DAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATP 986

Query: 122  LDHILSPPPMPFRKCSNPDVASGPGKSLKYKRQ 154
                L P P P          +G G S +  +Q
Sbjct: 987  APGALDPGPSPGTSGGKAAAGAGAGASSRSPKQ 1019



 Score = 35.0 bits (79), Expect = 0.061
 Identities = 31/110 (28%), Positives = 43/110 (39%), Gaps = 11/110 (10%)

Query: 10  EPVP----RGCSGHGSRTPASALVAAS-----SPGAS--SAESSSGSETLSEEGEPGGFS 58
           EP P    R  +G G + PAS  +++S     SP  S  SA  +  +     + +P G  
Sbjct: 219 EPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQ 278

Query: 59  REHQPPPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAP 108
               P   PP      A  P + +P +     G  A P P P  A  P P
Sbjct: 279 ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLP 328



 Score = 32.3 bits (72), Expect = 0.40
 Identities = 45/173 (26%), Positives = 61/173 (35%), Gaps = 21/173 (12%)

Query: 8   APEPVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPP 67
           AP   P   +G  SR PAS   A+     +    ++    +S  G   G +R   P P  
Sbjct: 74  APRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTR---PGPLG 130

Query: 68  PLGGTLGARAPAAWAPASVLLERGVLA------LPPPLPGGAVPPAPRGSSASQEEQDEE 121
             G  + A    A   A+   +R  L+         P PG   P   R S A+  E    
Sbjct: 131 QKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE---- 186

Query: 122 LDHILSPPPMPFRKCSNPDVASGPGKSLKYKRQLS---EDGRQLRRGSLGGAL 171
              +  P P P  +   P    GP KS+    + S         RR S GG L
Sbjct: 187 ---VGLPRPAPSARPRPP--TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGL 234



 Score = 28.1 bits (61), Expect = 7.5
 Identities = 16/44 (36%), Positives = 19/44 (43%), Gaps = 4/44 (9%)

Query: 64  PPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPA 107
           PP PPL   L    P+  AP S+      L  PP  P    PP+
Sbjct: 332 PPSPPLATPLPLAPPSPSAPPSL----QTLPSPPATPPSQAPPS 371


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 44.7 bits (104), Expect = 8e-05
 Identities = 44/153 (28%), Positives = 57/153 (37%), Gaps = 16/153 (10%)

Query: 8   APEPVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPP 67
           AP P P       SR+P+S L      G SS+ +S+  E    +  P G +    PP   
Sbjct: 569 APGPPPPP-----SRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPP--- 620

Query: 68  PLGGTLGARAPAAWA--PASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEE---- 121
                L A  PAAW+  PA  L  RG    P P P    P +  G     E +  E    
Sbjct: 621 --DAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATP 678

Query: 122 LDHILSPPPMPFRKCSNPDVASGPGKSLKYKRQ 154
               L P P P          +G G S +  +Q
Sbjct: 679 APGALDPGPSPGTSGGKAAAGAGAGASSRSPKQ 711



 Score = 30.8 bits (68), Expect = 1.2
 Identities = 34/129 (26%), Positives = 44/129 (34%), Gaps = 20/129 (15%)

Query: 24  PASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPPPLGGTLGARAPAAWAP 83
           P      A  P +SS  ++           P        PP  PP   T    +P   A 
Sbjct: 279 PRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQAT 338

Query: 84  ASVLLERGV--LALPPP-------LPGGAVPPAPRGS-------SASQEEQDEELDHIL- 126
            S L    +  LA PPP       LP    PP+P  S       + S +  +    H+L 
Sbjct: 339 HSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ 398

Query: 127 ---SPPPMP 132
              SPPP P
Sbjct: 399 APFSPPPSP 407



 Score = 29.6 bits (65), Expect = 2.6
 Identities = 29/89 (32%), Positives = 35/89 (39%), Gaps = 5/89 (5%)

Query: 21  SRTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPPPLGGTLGARA-PA 79
           S  P+  + A  SP AS   S S   T   +  P   +   Q PP PP    +   A P 
Sbjct: 402 SPPPSPPVQAPFSPPASPPVSPSA--TPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPP 459

Query: 80  AWAPASVLLERGVLALPPPL--PGGAVPP 106
             AP  +      LA PPP   P  A PP
Sbjct: 460 PQAPPPLAAPPLQLAKPPPQAPPALATPP 488


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 47/163 (28%), Positives = 58/163 (35%), Gaps = 29/163 (17%)

Query: 2    GEKVSEAPEPVPRGCSGHGSRT-PASALVAASSPGASSAESSSGSETLSEEGEPGGFSRE 60
            G + S  P P   G  G   R  P      A  PG        G +    E  P G   E
Sbjct: 863  GARGSAGP-PGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGE 921

Query: 61   HQPPPPPPLGGTLG-------ARAPAAWAPASVLLERGVLALP--------PPLPGGAVP 105
              PP PP   G  G       A AP    P  +  +RGV+ LP        P LPG +  
Sbjct: 922  VGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGE 981

Query: 106  PAPRGSSASQEEQDEELDHILSPPPMPFRKCSNPDVASGPGKS 148
            P  +G S +  E+          PP P      P +A  PG+S
Sbjct: 982  PGKQGPSGASGERG---------PPGPM---GPPGLAGPPGES 1012



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 41/123 (33%), Positives = 51/123 (41%), Gaps = 20/123 (16%)

Query: 2   GEKVSEAPEPVPRGCSGHGSRTPASALVAASSPGASSAESSSGSE-TLSEEGEPGGFSRE 60
           GE+ S  P   P+G  G   R   + L     PGA     S GS     + G PG   ++
Sbjct: 509 GERGSPGPAG-PKGSPGEAGRPGEAGL-----PGAKGLTGSPGSPGPDGKTGPPGPAGQD 562

Query: 61  HQPPPPPPLG-----GTLGARAP--AAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSA 113
            +P PP P G     G +G   P  AA  P     ERGV     P P GAV PA +   A
Sbjct: 563 GRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKA-GERGV-----PGPPGAVGPAGKDGEA 616

Query: 114 SQE 116
             +
Sbjct: 617 GAQ 619



 Score = 38.5 bits (88), Expect = 0.006
 Identities = 43/153 (28%), Positives = 51/153 (33%), Gaps = 22/153 (14%)

Query: 13   PRGCSGH-GSRTPASALVAASSPGASSAESSSGSE-TLSEEGEPGGFSREHQPPPPPPLG 70
            P G SG  G   P      A  PG S  E + G+E +   +G PG      +  P  P G
Sbjct: 987  PSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPG 1046

Query: 71   GTLGARAPAAWAPASVLLERGVLALPPP--------LPGGAVPPAPRGSSASQEEQDEE- 121
                  AP    PA    +RG      P          G A P  PRG      EQ +  
Sbjct: 1047 APGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRG 1106

Query: 122  ---------LDHILSPPPMPFRKCSNPDVASGP 145
                     L     PP  P  +   P  ASGP
Sbjct: 1107 IKGHRGFSGLQGPPGPPGSPGEQ--GPSGASGP 1137



 Score = 36.6 bits (83), Expect = 0.021
 Identities = 42/121 (34%), Positives = 48/121 (39%), Gaps = 22/121 (18%)

Query: 8    APEPV-PRGCSGHGSRT----PASAL--VAASSPGASSAESSSGSETLSEEGEPG----- 55
            AP PV P G SG    T    PA  +  V A  P           ET  E+G+ G     
Sbjct: 1053 APGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGET-GEQGDRGIKGHR 1111

Query: 56   GFSREHQPPPPPPLGGTLGARAPA-AWAPASVLLERGVLALPPP-----LPGGAVPPAPR 109
            GFS    PP PP   G+ G + P+ A  PA      G    P       LPG   PP PR
Sbjct: 1112 GFSGLQGPPGPP---GSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPR 1168

Query: 110  G 110
            G
Sbjct: 1169 G 1169



 Score = 32.3 bits (72), Expect = 0.40
 Identities = 49/197 (24%), Positives = 65/197 (32%), Gaps = 38/197 (19%)

Query: 11  PVPRGCSGHGSRTPASALVAASSP-------GASSAESSSGSETLSEEGEPGGFSREHQP 63
           P P G  G+   T A+     + P       GA  A+  +G +     G  G      +P
Sbjct: 316 PGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQ--GPRGSEGPQGVRGEP 373

Query: 64  PPPPPLGGTLGARAPAAWAPASVLLERGV--LALPPPLPGG---------AVPPAPRGSS 112
            PP P G    A  P A          G   +A  P  PG            PP P+G+S
Sbjct: 374 GPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNS 433

Query: 113 ASQEEQDEELDHILSPPPMPFRKCSNPDVASGPGKSLKYKRQLSEDGRQLRRGSLGGALT 172
                   + D      P P        V   PG +        E+G++  RG  G   T
Sbjct: 434 GEPGAPGSKGDTGAKGEPGPV------GVQGPPGPA-------GEEGKRGARGEPGP--T 478

Query: 173 GRYLLPNPVAGQAWPAS 189
           G   LP P   +  P S
Sbjct: 479 G---LPGPPGERGGPGS 492


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 46/164 (28%), Positives = 53/164 (32%), Gaps = 38/164 (23%)

Query: 9    PEPVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPPP 68
            P P P  C+   S  P   +V    P        +   T   +  P     E  PPPPPP
Sbjct: 856  PSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQ-GTEMLPPPPPP 914

Query: 69   LGGT-------------------LGARAP-------AAWAPASVLLERGVLALPPPLPGG 102
            L G                     GA  P       AA  P   L   G+  LPPPLPG 
Sbjct: 915  LPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGI-PLPPPLPGA 973

Query: 103  AVPPAPRGSSASQEEQDEELDHILSPPPMPFRKCSNPDVASGPG 146
             +PP P    A           I  PPP+P      P    G G
Sbjct: 974  GIPPPPPLPGAG----------IPPPPPLPGAGIPPPPPLPGAG 1007



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 30/86 (34%), Positives = 33/86 (38%), Gaps = 13/86 (15%)

Query: 64   PPPPPLGGT---LGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDE 120
            PPPPPL G    L    P A  P    L    +  PPPLPG  +PP P    A       
Sbjct: 954  PPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG------ 1007

Query: 121  ELDHILSPPPMPFRKCSNPDVASGPG 146
                I  PPP+P      P    G G
Sbjct: 1008 ----IPPPPPLPGAGIPPPPPLPGAG 1029



 Score = 41.2 bits (95), Expect = 9e-04
 Identities = 26/69 (37%), Positives = 29/69 (42%), Gaps = 18/69 (26%)

Query: 64   PPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELD 123
            PPPPPL        P A  P    L R  +  PPPLPG  +PP P    A          
Sbjct: 1130 PPPPPL--------PGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAG--------- 1172

Query: 124  HILSPPPMP 132
             I  PPP+P
Sbjct: 1173 -IPPPPPLP 1180



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 28/83 (33%), Positives = 31/83 (37%), Gaps = 18/83 (21%)

Query: 64   PPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELD 123
            PPPPPL        P A  P    L    +  PPPLPG  +PP P    A          
Sbjct: 976  PPPPPL--------PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG--------- 1018

Query: 124  HILSPPPMPFRKCSNPDVASGPG 146
             I  PPP+P      P    G G
Sbjct: 1019 -IPPPPPLPGAGIPPPPPLPGAG 1040



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 28/83 (33%), Positives = 31/83 (37%), Gaps = 18/83 (21%)

Query: 64   PPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELD 123
            PPPPPL        P A  P    L    +  PPPLPG  +PP P    A          
Sbjct: 987  PPPPPL--------PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG--------- 1029

Query: 124  HILSPPPMPFRKCSNPDVASGPG 146
             I  PPP+P      P    G G
Sbjct: 1030 -IPPPPPLPGAGIPPPPPLPGAG 1051



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 28/83 (33%), Positives = 31/83 (37%), Gaps = 18/83 (21%)

Query: 64   PPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELD 123
            PPPPPL        P A  P    L    +  PPPLPG  +PP P    A          
Sbjct: 998  PPPPPL--------PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG--------- 1040

Query: 124  HILSPPPMPFRKCSNPDVASGPG 146
             I  PPP+P      P    G G
Sbjct: 1041 -IPPPPPLPGAGIPPPPPLPGAG 1062



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 28/83 (33%), Positives = 31/83 (37%), Gaps = 18/83 (21%)

Query: 64   PPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELD 123
            PPPPPL        P A  P    L    +  PPPLPG  +PP P    A          
Sbjct: 1009 PPPPPL--------PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG--------- 1051

Query: 124  HILSPPPMPFRKCSNPDVASGPG 146
             I  PPP+P      P    G G
Sbjct: 1052 -IPPPPPLPGAGIPPPPPLPGAG 1073



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 28/83 (33%), Positives = 31/83 (37%), Gaps = 18/83 (21%)

Query: 64   PPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELD 123
            PPPPPL        P A  P    L    +  PPPLPG  +PP P    A          
Sbjct: 1020 PPPPPL--------PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG--------- 1062

Query: 124  HILSPPPMPFRKCSNPDVASGPG 146
             I  PPP+P      P    G G
Sbjct: 1063 -IPPPPPLPGAGIPPPPPLPGAG 1084



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 28/83 (33%), Positives = 31/83 (37%), Gaps = 18/83 (21%)

Query: 64   PPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELD 123
            PPPPPL        P A  P    L    +  PPPLPG  +PP P    A          
Sbjct: 1031 PPPPPL--------PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG--------- 1073

Query: 124  HILSPPPMPFRKCSNPDVASGPG 146
             I  PPP+P      P    G G
Sbjct: 1074 -IPPPPPLPGAGIPPPPPLPGAG 1095



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 28/83 (33%), Positives = 31/83 (37%), Gaps = 18/83 (21%)

Query: 64   PPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELD 123
            PPPPPL        P A  P    L    +  PPPLPG  +PP P    A          
Sbjct: 1042 PPPPPL--------PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG--------- 1084

Query: 124  HILSPPPMPFRKCSNPDVASGPG 146
             I  PPP+P      P    G G
Sbjct: 1085 -IPPPPPLPGAGIPPPPPLPGVG 1106



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 28/83 (33%), Positives = 31/83 (37%), Gaps = 18/83 (21%)

Query: 64   PPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELD 123
            PPPPPL        P A  P    L    +  PPPLPG  +PP P    A          
Sbjct: 1053 PPPPPL--------PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG--------- 1095

Query: 124  HILSPPPMPFRKCSNPDVASGPG 146
             I  PPP+P      P    G G
Sbjct: 1096 -IPPPPPLPGVGIPPPPPLPGAG 1117



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 27/86 (31%), Positives = 31/86 (36%), Gaps = 20/86 (23%)

Query: 64   PPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELD 123
            PPPPPL        P A  P    L    +  PPPLPG  +PP P             L 
Sbjct: 1108 PPPPPL--------PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP------------PLP 1147

Query: 124  HILSPPPMPFRKCSNPDVASGPGKSL 149
             +  PPP P      P     PG  +
Sbjct: 1148 RVGIPPPPPLPGAGIPPPPPLPGAGI 1173



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 28/83 (33%), Positives = 31/83 (37%), Gaps = 18/83 (21%)

Query: 64   PPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELD 123
            PPPPPL        P A  P    L    +  PPPLPG  +PP P    A          
Sbjct: 1075 PPPPPL--------PGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAG--------- 1117

Query: 124  HILSPPPMPFRKCSNPDVASGPG 146
             I  PPP+P      P    G G
Sbjct: 1118 -IPPPPPLPGAGIPPPPPLPGAG 1139



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 27/83 (32%), Positives = 30/83 (36%), Gaps = 18/83 (21%)

Query: 64   PPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELD 123
            PPPPPL        P A  P    L    +  PPPLPG  +PP P               
Sbjct: 1064 PPPPPL--------PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVG--------- 1106

Query: 124  HILSPPPMPFRKCSNPDVASGPG 146
             I  PPP+P      P    G G
Sbjct: 1107 -IPPPPPLPGAGIPPPPPLPGAG 1128



 Score = 38.1 bits (87), Expect = 0.007
 Identities = 27/86 (31%), Positives = 31/86 (36%), Gaps = 20/86 (23%)

Query: 64   PPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELD 123
            PPPPPL        P A  P    L    +  PPPLPG  +PP P             L 
Sbjct: 1152 PPPPPL--------PGAGIPPPPPLPGAGIPPPPPLPGVGIPPPP------------PLP 1191

Query: 124  HILSPPPMPFRKCSNPDVASGPGKSL 149
             +  PPP P      P     PG  +
Sbjct: 1192 GVGIPPPPPLPGAGIPPPPPLPGMGI 1217



 Score = 37.0 bits (84), Expect = 0.016
 Identities = 26/86 (30%), Positives = 30/86 (34%), Gaps = 20/86 (23%)

Query: 64   PPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELD 123
            PPPPPL        P    P    L    +  PPPLPG  +PP P             L 
Sbjct: 1141 PPPPPL--------PRVGIPPPPPLPGAGIPPPPPLPGAGIPPPP------------PLP 1180

Query: 124  HILSPPPMPFRKCSNPDVASGPGKSL 149
             +  PPP P      P     PG  +
Sbjct: 1181 GVGIPPPPPLPGVGIPPPPPLPGAGI 1206



 Score = 36.6 bits (83), Expect = 0.021
 Identities = 19/45 (42%), Positives = 21/45 (46%), Gaps = 8/45 (17%)

Query: 64   PPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAP 108
            PPPPPL        P    P    L    +  PPPLPG  +PPAP
Sbjct: 1185 PPPPPL--------PGVGIPPPPPLPGAGIPPPPPLPGMGIPPAP 1221



 Score = 36.2 bits (82), Expect = 0.028
 Identities = 27/83 (32%), Positives = 30/83 (36%), Gaps = 18/83 (21%)

Query: 64   PPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELD 123
            PPPPPL        P A  P    L    +  PPPLP   +PP P    A          
Sbjct: 1119 PPPPPL--------PGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAG--------- 1161

Query: 124  HILSPPPMPFRKCSNPDVASGPG 146
             I  PPP+P      P    G G
Sbjct: 1162 -IPPPPPLPGAGIPPPPPLPGVG 1183



 Score = 33.1 bits (74), Expect = 0.23
 Identities = 32/125 (25%), Positives = 40/125 (32%), Gaps = 39/125 (31%)

Query: 62  QPPPPPPLGGTLGARAPAAWAPASVLLE-------------------------------- 89
           QPPPPP L  + G   P +  P S+  E                                
Sbjct: 809 QPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSS 868

Query: 90  -----RGVLALPPPLPGGAVPPAPRGSSASQEEQDEELDHILSPPPMPFRKCSNPDVASG 144
                  V   PPPLPG  VP  P  S+A  +    +   +L PPP P      P     
Sbjct: 869 SMPGLGMVPPPPPPLPGMTVPTLP--STAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPL 926

Query: 145 PGKSL 149
           PG  +
Sbjct: 927 PGAGI 931



 Score = 28.1 bits (61), Expect = 7.5
 Identities = 17/45 (37%), Positives = 18/45 (40%), Gaps = 15/45 (33%)

Query: 64   PPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAP 108
            PPPPPL G     APA                P P PG  +PP P
Sbjct: 1207 PPPPPLPGMGIPPAPAP---------------PLPPPGTGIPPPP 1236



 Score = 27.7 bits (60), Expect = 9.8
 Identities = 24/93 (25%), Positives = 34/93 (36%), Gaps = 1/93 (1%)

Query: 30  AASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPPPLGGTLGARAPAAWAPASVLLE 89
           A  +PG+   E +  + +   E          QPP P  L  +     PAA   A     
Sbjct: 260 AGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPS 319

Query: 90  RGVLALPPPLPGGAVPPAP-RGSSASQEEQDEE 121
                 P   PG     AP RG+  + EE +E+
Sbjct: 320 STAFPFPEAGPGEEAAGAPVRGAGDTDEEGEED 352


>gi|56549694 enabled homolog isoform a [Homo sapiens]
          Length = 591

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 52/157 (33%), Positives = 68/157 (43%), Gaps = 33/157 (21%)

Query: 23  TPASALV---AASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPPPLGGTLGARAPA 79
           TP ++++   +AS PG  +A  S  +ET S++G   G      PPPPPPL        P 
Sbjct: 275 TPLNSVLGDSSASEPGLQAA--SQPAETPSQQGIVLG---PLAPPPPPPL--------PP 321

Query: 80  AWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELDHILSPPPMPFRKCSNP 139
             A ASV       ALPPP PG   PP    +          L + + PPP P    + P
Sbjct: 322 GPAQASV-------ALPPP-PGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPP--PPAPP 371

Query: 140 DVASGPGKSLKYKRQLSEDGRQLRRGSLGGALTGRYL 176
             ASG      +   +SED R L    L  A+ G  L
Sbjct: 372 LPASG-----FFLASMSEDNRPLT--GLAAAIAGAKL 401


>gi|39930375 enabled homolog isoform b [Homo sapiens]
          Length = 570

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 52/157 (33%), Positives = 68/157 (43%), Gaps = 33/157 (21%)

Query: 23  TPASALV---AASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPPPLGGTLGARAPA 79
           TP ++++   +AS PG  +A  S  +ET S++G   G      PPPPPPL        P 
Sbjct: 275 TPLNSVLGDSSASEPGLQAA--SQPAETPSQQGIVLG---PLAPPPPPPL--------PP 321

Query: 80  AWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELDHILSPPPMPFRKCSNP 139
             A ASV       ALPPP PG   PP    +          L + + PPP P    + P
Sbjct: 322 GPAQASV-------ALPPP-PGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPP--PPAPP 371

Query: 140 DVASGPGKSLKYKRQLSEDGRQLRRGSLGGALTGRYL 176
             ASG      +   +SED R L    L  A+ G  L
Sbjct: 372 LPASG-----FFLASMSEDNRPLT--GLAAAIAGAKL 401


>gi|24431935 reticulon 4 isoform A [Homo sapiens]
          Length = 1192

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 39/127 (30%), Positives = 56/127 (44%), Gaps = 20/127 (15%)

Query: 23  TPASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPPPLGGTLGARAPAAWA 82
           +P S+ V A SP +++A S S    L E+ EP       +PPPPPP   ++  +A   W 
Sbjct: 111 SPVSSTVPAPSPLSAAAVSPS---KLPEDDEPPA-----RPPPPPP--ASVSPQAEPVWT 160

Query: 83  PASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELDHILSPPPMPFRKCSNPDVA 142
           P +        A PP  P     P  RGSS S +E    L    +  P+      N D+ 
Sbjct: 161 PPA-----PAPAAPPSTPAA---PKRRGSSGSVDETLFALP--AASEPVIRSSAENMDLK 210

Query: 143 SGPGKSL 149
             PG ++
Sbjct: 211 EQPGNTI 217



 Score = 27.7 bits (60), Expect = 9.8
 Identities = 20/65 (30%), Positives = 25/65 (38%), Gaps = 1/65 (1%)

Query: 68  PLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELDHILS 127
           P  G   A  P A A  + L++ G     PP P G +P AP  +   Q   D        
Sbjct: 59  PAAGLSAAPVPTAPAAGAPLMDFGN-DFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTV 117

Query: 128 PPPMP 132
           P P P
Sbjct: 118 PAPSP 122


>gi|39812378 RAN binding protein 9 [Homo sapiens]
          Length = 729

 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 35/118 (29%), Positives = 42/118 (35%), Gaps = 21/118 (17%)

Query: 24  PASALVAASSPGASSAESSSGSETLSEEGEPGGFSRE----HQPPPPPPLGGTLGARAPA 79
           P S +V  + P  S+  S +GS      GE  G +      H PPPPPP         P 
Sbjct: 29  PVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAAAALLLHPPPPPPPATAAPPPPPPP 88

Query: 80  AWAPASVLLERGVLALPP-----PLPGGAVP------------PAPRGSSASQEEQDE 120
              PAS          PP     P P G  P            P P G SA  E++ E
Sbjct: 89  PPPPASAAAPASGPPAPPGLAAGPGPAGGAPTPALVAGSSAAAPFPHGDSALNEQEKE 146



 Score = 37.4 bits (85), Expect = 0.012
 Identities = 27/75 (36%), Positives = 31/75 (41%), Gaps = 8/75 (10%)

Query: 62  QPPPPPPLGGT----LGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEE 117
           QPPPPPP        L    PAA AP S +    VL  PP +  G+ P    G  A  E 
Sbjct: 4   QPPPPPPQQQQQQQQLSPPPPAALAPVSGV----VLPAPPAVSAGSSPAGSPGGGAGGEG 59

Query: 118 QDEELDHILSPPPMP 132
                  +L  PP P
Sbjct: 60  LGAAAAALLLHPPPP 74


>gi|169213924 PREDICTED: leucine rich repeat containing 68 [Homo
           sapiens]
          Length = 625

 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 44/143 (30%), Positives = 56/143 (39%), Gaps = 33/143 (23%)

Query: 1   MGEKVSEAPEPVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEGE----PGG 56
           M E  +  P+P     +G  +  P+ A     SP + S   S G E   EEGE    P G
Sbjct: 487 MPETTATEPQPDDEPAAGVQNGAPSPA----PSPDSDSDSDSDGEEEEEEEGERDETPSG 542

Query: 57  F-------SREHQPPPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPR 109
                   S E QPPP PP     G   P    P         LALPP  P G   P  +
Sbjct: 543 AIDTRDTGSSEPQPPPEPPRS---GPPLPNGLKP------EFALALPPEPPPG---PEVK 590

Query: 110 GSSASQEEQ------DEELDHIL 126
           G S   E +      ++EL+ +L
Sbjct: 591 GGSCGLEHELSCSKNEKELEELL 613


>gi|169214345 PREDICTED: leucine rich repeat containing 68 [Homo
           sapiens]
          Length = 625

 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 44/143 (30%), Positives = 56/143 (39%), Gaps = 33/143 (23%)

Query: 1   MGEKVSEAPEPVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEGE----PGG 56
           M E  +  P+P     +G  +  P+ A     SP + S   S G E   EEGE    P G
Sbjct: 487 MPETTATEPQPDDEPAAGVQNGAPSPA----PSPDSDSDSDSDGEEEEEEEGERDETPSG 542

Query: 57  F-------SREHQPPPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPR 109
                   S E QPPP PP     G   P    P         LALPP  P G   P  +
Sbjct: 543 AIDTRDTGSSEPQPPPEPPRS---GPPLPNGLKP------EFALALPPEPPPG---PEVK 590

Query: 110 GSSASQEEQ------DEELDHIL 126
           G S   E +      ++EL+ +L
Sbjct: 591 GGSCGLEHELSCSKNEKELEELL 613


>gi|169213302 PREDICTED: leucine rich repeat containing 68 [Homo
           sapiens]
          Length = 625

 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 44/143 (30%), Positives = 56/143 (39%), Gaps = 33/143 (23%)

Query: 1   MGEKVSEAPEPVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEGE----PGG 56
           M E  +  P+P     +G  +  P+ A     SP + S   S G E   EEGE    P G
Sbjct: 487 MPETTATEPQPDDEPAAGVQNGAPSPA----PSPDSDSDSDSDGEEEEEEEGERDETPSG 542

Query: 57  F-------SREHQPPPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPR 109
                   S E QPPP PP     G   P    P         LALPP  P G   P  +
Sbjct: 543 AIDTRDTGSSEPQPPPEPPRS---GPPLPNGLKP------EFALALPPEPPPG---PEVK 590

Query: 110 GSSASQEEQ------DEELDHIL 126
           G S   E +      ++EL+ +L
Sbjct: 591 GGSCGLEHELSCSKNEKELEELL 613


>gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Homo
           sapiens]
          Length = 305

 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 48/163 (29%), Positives = 63/163 (38%), Gaps = 16/163 (9%)

Query: 24  PASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPPPLGGTLGARAPA-AWA 82
           P +  VA S P   +AES  G E   E+            PPP P+     A APA   A
Sbjct: 97  PVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAA 156

Query: 83  PASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELDHILSPPPMPFRKCSNPDVA 142
           P +  +   VLA P P P  A  PAP   +A             +P P P      PD A
Sbjct: 157 PVAAPVAVAVLA-PAPAPAPAPAPAPAPVAAPAPAPAP------APAPAP-APAPAPDAA 208

Query: 143 SGPGKSLKYKRQLSEDGRQLRRGSLGGALTGRYLLPNPVAGQA 185
             P +S +      + G++     L   ++GR     P AG A
Sbjct: 209 --PQESAEQGANQGQRGQEPLADQLHSGISGR-----PAAGTA 244


>gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Homo
           sapiens]
          Length = 305

 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 48/163 (29%), Positives = 63/163 (38%), Gaps = 16/163 (9%)

Query: 24  PASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPPPLGGTLGARAPA-AWA 82
           P +  VA S P   +AES  G E   E+            PPP P+     A APA   A
Sbjct: 97  PVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAA 156

Query: 83  PASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELDHILSPPPMPFRKCSNPDVA 142
           P +  +   VLA P P P  A  PAP   +A             +P P P      PD A
Sbjct: 157 PVAAPVAVAVLA-PAPAPAPAPAPAPAPVAAPAPAPAP------APAPAP-APAPAPDAA 208

Query: 143 SGPGKSLKYKRQLSEDGRQLRRGSLGGALTGRYLLPNPVAGQA 185
             P +S +      + G++     L   ++GR     P AG A
Sbjct: 209 --PQESAEQGANQGQRGQEPLADQLHSGISGR-----PAAGTA 244


>gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo
           sapiens]
          Length = 316

 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 48/163 (29%), Positives = 63/163 (38%), Gaps = 16/163 (9%)

Query: 24  PASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPPPLGGTLGARAPA-AWA 82
           P +  VA S P   +AES  G E   E+            PPP P+     A APA   A
Sbjct: 108 PVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAA 167

Query: 83  PASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELDHILSPPPMPFRKCSNPDVA 142
           P +  +   VLA P P P  A  PAP   +A             +P P P      PD A
Sbjct: 168 PVAAPVAVAVLA-PAPAPAPAPAPAPAPVAAPAPAPAP------APAPAP-APAPAPDAA 219

Query: 143 SGPGKSLKYKRQLSEDGRQLRRGSLGGALTGRYLLPNPVAGQA 185
             P +S +      + G++     L   ++GR     P AG A
Sbjct: 220 --PQESAEQGANQGQRGQEPLADQLHSGISGR-----PAAGTA 255


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 44/165 (26%), Positives = 57/165 (34%), Gaps = 24/165 (14%)

Query: 11  PVPRGCSGHGSRTPASALVAASSPGASSAESS----SGSETLSEEGEPGGFSREHQPPPP 66
           P P+G  G    T        + PG    ++      G + L   G P G     +P  P
Sbjct: 602 PGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPG--ENGKPGEP 659

Query: 67  PPLGGTLGARAPAAWAPASVLLERGV--LALPPPLPGGAVPPAPRGSSASQEEQDEELDH 124
            P G      AP     A    ERG   LA  P L GGA PP P G   +          
Sbjct: 660 GPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGA---------- 709

Query: 125 ILSPPPMPFRKCSNPDVASGPGKSLKYKRQLSEDGRQLRRGSLGG 169
             + PP P      P +   PG+    +  L   G +  +G  GG
Sbjct: 710 --AGPPGPPGAAGTPGLQGMPGE----RGGLGSPGPKGDKGEPGG 748



 Score = 37.7 bits (86), Expect = 0.009
 Identities = 31/107 (28%), Positives = 43/107 (40%), Gaps = 20/107 (18%)

Query: 11  PVPRGCSGH-GSRTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPPPL 69
           P P G +G  GS      +  A SPG++ A    G      E  P G +    PP PP +
Sbjct: 335 PGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRG------EPGPQGHAGAQGPPGPPGI 388

Query: 70  GGTLGARAPAAWAPASVLLERGVLALP--PPLPGGAVPPAPRGSSAS 114
            G+ G +            E G   +P  P L G   PP P G++ +
Sbjct: 389 NGSPGGKG-----------EMGPAGIPGAPGLMGARGPPGPAGANGA 424



 Score = 33.9 bits (76), Expect = 0.14
 Identities = 39/137 (28%), Positives = 47/137 (34%), Gaps = 18/137 (13%)

Query: 2    GEKVSEAPEPVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLS-EEGEPG--GFS 58
            GEK S   +  P      G      A   A  PG      S G + +  E G+PG  G S
Sbjct: 930  GEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLS 989

Query: 59   REHQPPPP---PPLGGTLGARA----------PAAWAPASVLLERGVLALP--PPLPGGA 103
             E  PP P   P L GT G             P          +RG    P  P  PG  
Sbjct: 990  GERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHP 1049

Query: 104  VPPAPRGSSASQEEQDE 120
             PP P G +    ++ E
Sbjct: 1050 GPPGPVGPAGKSGDRGE 1066



 Score = 32.0 bits (71), Expect = 0.52
 Identities = 48/189 (25%), Positives = 56/189 (29%), Gaps = 36/189 (19%)

Query: 8    APEPVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPP 67
            A  P P+G  G   R       AA  PGA       GS      G PG      +  PP 
Sbjct: 851  AGPPGPQGVKGE--RGSPGGPGAAGFPGARGLPGPPGSN--GNPGPPGPSGSPGKDGPPG 906

Query: 68   PLGGTLGARAPAAWAP---------------------------ASVLLERGVLALPPPLP 100
            P G T    +P    P                           A +   RG LA PP +P
Sbjct: 907  PAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARG-LAGPPGMP 965

Query: 101  GGAVPPAPRGSSASQEEQDEELDHILSPPPMPFRKCSNPDVASGPGKSLKYKRQLSEDGR 160
            G    P P+G      +           PP P         A  PG+          DG 
Sbjct: 966  GPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRD----GNPGSDGL 1021

Query: 161  QLRRGSLGG 169
              R GS GG
Sbjct: 1022 PGRDGSPGG 1030



 Score = 29.6 bits (65), Expect = 2.6
 Identities = 35/133 (26%), Positives = 43/133 (32%), Gaps = 32/133 (24%)

Query: 7    EAPEPVPRGCSGH-GSRTPASALVAASSPGASSAESSSGSETL-------------SEEG 52
            E+ +P   G SG  G   P      A + G    + + GS+ L              E G
Sbjct: 979  ESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENG 1038

Query: 53   EPGGFSREHQPPPPPPLG-----GTLGARAPA--AWAPASVLLERGVLALPPPLPGGAVP 105
             PG       P PP P+G     G  G   PA  A AP            P    G   P
Sbjct: 1039 SPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPG-----------PAGSRGAPGP 1087

Query: 106  PAPRGSSASQEEQ 118
              PRG      E+
Sbjct: 1088 QGPRGDKGETGER 1100



 Score = 29.6 bits (65), Expect = 2.6
 Identities = 32/110 (29%), Positives = 39/110 (35%), Gaps = 7/110 (6%)

Query: 8    APEPV-PRGCSGHGSRTPASALVA----ASSPGASSAESSSGSETLSEEGEPGGFSREHQ 62
            AP P  PRG  G      A+ +        +PGA  +   +G +       P G      
Sbjct: 1084 APGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVG 1143

Query: 63   PPPPPPLGGTLGARAP-AAWAPASVLLERGVLALPPPLPGGAVPPAPRGS 111
            P  PP   GT G   P     P     ERG     P  PG   PP P G+
Sbjct: 1144 PSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEG-SPGHPGQPGPPGPPGA 1192



 Score = 29.3 bits (64), Expect = 3.4
 Identities = 35/117 (29%), Positives = 41/117 (35%), Gaps = 19/117 (16%)

Query: 8   APEPV-PRGCSGHGSRTPASALVAASS-PGASSAESSSGSETLSEEGEPGGFSREHQPPP 65
           AP P  PRG +G   R            PG+     S G     + G PG      +P P
Sbjct: 511 APGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDG-----KPGPPGSQGESGRPGP 565

Query: 66  PPPLG-----GTLGARAPAA--WAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQ 115
           P P G     G +G   P     AP     ERG     P  PG   PP   G +  Q
Sbjct: 566 PGPSGPRGQPGVMGFPGPKGNDGAPGK-NGERG----GPGGPGPQGPPGKNGETGPQ 617


>gi|47519490 reticulon 4 isoform D [Homo sapiens]
          Length = 392

 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 33/95 (34%), Positives = 45/95 (47%), Gaps = 18/95 (18%)

Query: 23  TPASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPPPLGGTLGARAPAAWA 82
           +P S+ V A SP +++A S S    L E+ EP       +PPPPPP   ++  +A   W 
Sbjct: 111 SPVSSTVPAPSPLSAAAVSPS---KLPEDDEPPA-----RPPPPPP--ASVSPQAEPVWT 160

Query: 83  PASVLLERGVLALPPPLPGGAVPPAPRGSSASQEE 117
           P +        A PP  P     P  RGSS S +E
Sbjct: 161 PPA-----PAPAAPPSTPAA---PKRRGSSGSVDE 187



 Score = 27.7 bits (60), Expect = 9.8
 Identities = 20/65 (30%), Positives = 25/65 (38%), Gaps = 1/65 (1%)

Query: 68  PLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELDHILS 127
           P  G   A  P A A  + L++ G     PP P G +P AP  +   Q   D        
Sbjct: 59  PAAGLSAAPVPTAPAAGAPLMDFGN-DFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTV 117

Query: 128 PPPMP 132
           P P P
Sbjct: 118 PAPSP 122


>gi|239754138 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 274

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 41/148 (27%), Positives = 52/148 (35%), Gaps = 24/148 (16%)

Query: 34  PGASSAESSSGSETLSEEGEPGGFSREHQPPPPPPLGG--TLGARAPAA-----WAPASV 86
           PG  S   S  S        P       +PPPPPP      LGAR  A       A  S 
Sbjct: 42  PGPPSRSRSPSSRLKLPADPPRALPGSPEPPPPPPPAAPHVLGARVAAGPTHRLSASHSR 101

Query: 87  LLERGVLALPPPLPG----------GAVPPAPRGSSASQEEQDEELDHILSPPPMPFRKC 136
           +  RG +   P  PG           A P +PR  +A              PPP P R  
Sbjct: 102 VSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRARAARAISNQSS-----PPPPPPSRAR 156

Query: 137 SNPDVASGPGKSLKYKRQLSEDGRQLRR 164
           S     S PG   ++  + + +  +LRR
Sbjct: 157 SRSLRLSAPGS--RHDAEKASERNRLRR 182


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.129    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,142,191
Number of Sequences: 37866
Number of extensions: 967421
Number of successful extensions: 10917
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 232
Number of HSP's successfully gapped in prelim test: 1114
Number of HSP's that attempted gapping in prelim test: 6873
Number of HSP's gapped (non-prelim): 3630
length of query: 250
length of database: 18,247,518
effective HSP length: 100
effective length of query: 150
effective length of database: 14,460,918
effective search space: 2169137700
effective search space used: 2169137700
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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