BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|38488767 microtubule associated serine/threonine kinase family member 4 isoform b [Homo sapiens] (250 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|38488767 microtubule associated serine/threonine kinase famil... 507 e-144 gi|112363080 microtubule associated serine/threonine kinase 2 [H... 112 2e-25 gi|148727255 microtubule associated serine/threonine kinase fami... 54 1e-07 gi|112421108 capicua homolog [Homo sapiens] 47 2e-05 gi|163965366 nascent polypeptide-associated complex alpha subuni... 46 3e-05 gi|156104872 Ets2 repressor factor [Homo sapiens] 46 3e-05 gi|149999378 inverted formin 2 isoform 2 [Homo sapiens] 45 5e-05 gi|149999380 inverted formin 2 isoform 1 [Homo sapiens] 45 5e-05 gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 45 6e-05 gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 45 6e-05 gi|66932986 filamin-binding LIM protein-1 isoform b [Homo sapiens] 45 6e-05 gi|66932982 filamin-binding LIM protein-1 isoform a [Homo sapiens] 45 6e-05 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 45 8e-05 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 45 8e-05 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 45 8e-05 gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 44 1e-04 gi|160707881 formin 2 [Homo sapiens] 44 1e-04 gi|56549694 enabled homolog isoform a [Homo sapiens] 43 2e-04 gi|39930375 enabled homolog isoform b [Homo sapiens] 43 2e-04 gi|24431935 reticulon 4 isoform A [Homo sapiens] 43 2e-04 gi|39812378 RAN binding protein 9 [Homo sapiens] 42 4e-04 gi|169213924 PREDICTED: leucine rich repeat containing 68 [Homo ... 42 4e-04 gi|169214345 PREDICTED: leucine rich repeat containing 68 [Homo ... 42 4e-04 gi|169213302 PREDICTED: leucine rich repeat containing 68 [Homo ... 42 4e-04 gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Hom... 42 5e-04 gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Hom... 42 5e-04 gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo ... 42 5e-04 gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 42 7e-04 gi|47519490 reticulon 4 isoform D [Homo sapiens] 42 7e-04 gi|239754138 PREDICTED: hypothetical protein [Homo sapiens] 41 0.001 >gi|38488767 microtubule associated serine/threonine kinase family member 4 isoform b [Homo sapiens] Length = 250 Score = 507 bits (1306), Expect = e-144 Identities = 250/250 (100%), Positives = 250/250 (100%) Query: 1 MGEKVSEAPEPVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSRE 60 MGEKVSEAPEPVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSRE Sbjct: 1 MGEKVSEAPEPVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSRE 60 Query: 61 HQPPPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDE 120 HQPPPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDE Sbjct: 61 HQPPPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDE 120 Query: 121 ELDHILSPPPMPFRKCSNPDVASGPGKSLKYKRQLSEDGRQLRRGSLGGALTGRYLLPNP 180 ELDHILSPPPMPFRKCSNPDVASGPGKSLKYKRQLSEDGRQLRRGSLGGALTGRYLLPNP Sbjct: 121 ELDHILSPPPMPFRKCSNPDVASGPGKSLKYKRQLSEDGRQLRRGSLGGALTGRYLLPNP 180 Query: 181 VAGQAWPASAETSNLVRMRSQALGQSAPSLTASLKELSLPRRGSLIDSQKWNCLVKRPVC 240 VAGQAWPASAETSNLVRMRSQALGQSAPSLTASLKELSLPRRGSLIDSQKWNCLVKRPVC Sbjct: 181 VAGQAWPASAETSNLVRMRSQALGQSAPSLTASLKELSLPRRGSLIDSQKWNCLVKRPVC 240 Query: 241 PNAGRTSPLG 250 PNAGRTSPLG Sbjct: 241 PNAGRTSPLG 250 >gi|112363080 microtubule associated serine/threonine kinase 2 [Homo sapiens] Length = 1798 Score = 112 bits (281), Expect = 2e-25 Identities = 84/207 (40%), Positives = 111/207 (53%), Gaps = 32/207 (15%) Query: 62 QPPPPPPLGGTLGARAPAAWAPASVLLERGVLALPPP--LPGGAVPPAPRGSSASQEEQD 119 +P PPPP G + A + + LPP P G R A E ++ Sbjct: 9 RPQPPPPDRREDGVQRAAELSQS----------LPPRRRAPPGRQRLEERTGPAGPEGKE 58 Query: 120 EELDHILSPPPMPFRKCSNPDVASGPGKSLKYKRQLSEDGRQLRRGSLGGALTGRYLLP- 178 +++ + P+ FRK SNPD+ S GK +K +RQLS+D +L RG+L +L+G+ LLP Sbjct: 59 QDV--VTGVSPLLFRKLSNPDIFSSTGK-VKLQRQLSQDDCKLWRGNLASSLSGKQLLPL 115 Query: 179 -----NPVAGQAWPASAETSNLVRMRSQALGQSAPSLTASLKELSLPRRG---------S 224 + V W +S E SNLVRMR+Q+LGQSAPSLTA LKELSLPRRG S Sbjct: 116 SSSVHSSVGQVTWQSSGEASNLVRMRNQSLGQSAPSLTAGLKELSLPRRGSFCRTSNRKS 175 Query: 225 LIDSQKWNCLVKRPVCPNAGRT--SPL 249 LI + + + RP P G T SPL Sbjct: 176 LIVTSSTSPTLPRPHSPLHGHTGNSPL 202 >gi|148727255 microtubule associated serine/threonine kinase family member 4 isoform a [Homo sapiens] Length = 2434 Score = 54.3 bits (129), Expect = 1e-07 Identities = 27/36 (75%), Positives = 29/36 (80%), Gaps = 2/36 (5%) Query: 215 KELSLPRRGSLIDSQKWNCLVKRPVCPNAGRTSPLG 250 KELSLPRRGSLIDSQKWNCLVKR C + R S +G Sbjct: 14 KELSLPRRGSLIDSQKWNCLVKR--CRTSNRKSLIG 47 >gi|112421108 capicua homolog [Homo sapiens] Length = 1608 Score = 46.6 bits (109), Expect = 2e-05 Identities = 39/143 (27%), Positives = 53/143 (37%), Gaps = 3/143 (2%) Query: 9 PEPVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPPP 68 P+P G+GS +SA ASS +++ S GS T + G + PPPP Sbjct: 518 PDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQGSTAGPLRPPPPG 577 Query: 69 LGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELDHILSP 128 GG + P R P GG PP P +A L ++ P Sbjct: 578 AGGPATPSKATRFLPMDPATFR---RKRPESVGGLEPPGPSVIAAPPSGGGNILQTLVLP 634 Query: 129 PPMPFRKCSNPDVASGPGKSLKY 151 P ++ V S P SL Y Sbjct: 635 PNKEEQEGGGARVPSAPAPSLAY 657 Score = 30.0 bits (66), Expect = 2.0 Identities = 33/120 (27%), Positives = 49/120 (40%), Gaps = 20/120 (16%) Query: 24 PASALVAASSPGASS-AESSSGSETLSEEGEPGGFSREHQPPPPPPLGGTLGARAPAAWA 82 P+ A AS P AS+ ++ + S ++ E PGG PP GA P + Sbjct: 55 PSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPERPP-------GATCPESPG 107 Query: 83 PASV----LLERGVLALPPPL---PGGAVPPAPRGSSASQEEQDEELDHILSPP---PMP 132 P ++E G PPP P PR S ++ + D+ I+SP P+P Sbjct: 108 PGPPHPLGVVESG--KGPPPTTEEEASGPPGEPRLDSETESDHDDAFLSIMSPEIQLPLP 165 Score = 30.0 bits (66), Expect = 2.0 Identities = 32/114 (28%), Positives = 45/114 (39%), Gaps = 15/114 (13%) Query: 20 GSRTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPPPLGGTLGARAPA 79 G PA+A A +SP S+ ++GS T S + +P P P + A Sbjct: 1137 GPPAPATATPAPTSPFPSA---TAGSMTYSLVAP-----KAQRPSPKAP------QKVKA 1182 Query: 80 AWAPASV-LLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELDHILSPPPMP 132 A A V E G P P P + P P + E + E +PPP+P Sbjct: 1183 AIASIPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPLP 1236 Score = 29.6 bits (65), Expect = 2.6 Identities = 23/73 (31%), Positives = 29/73 (39%), Gaps = 19/73 (26%) Query: 78 PAAWAPASVLLERGVLALPPPLP---GGAVPPAPRGSSASQEEQDEELDHILSPPPMPFR 134 P A AP V G A P P P GG P +P S + + + PP+P Sbjct: 1529 PGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQ----------AAPPLP-- 1576 Query: 135 KCSNPDVASGPGK 147 P SGPG+ Sbjct: 1577 ----PPPESGPGQ 1585 Score = 28.5 bits (62), Expect = 5.8 Identities = 22/71 (30%), Positives = 27/71 (38%), Gaps = 11/71 (15%) Query: 6 SEAPEPVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETL---------SEEGEPGG 56 +EAP PVP + PA A P +S S SG+ S G+PG Sbjct: 1531 AEAPLPVPPPTGT--AAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESGPGQPGW 1588 Query: 57 FSREHQPPPPP 67 PPPP Sbjct: 1589 EGAPQPSPPPP 1599 Score = 27.7 bits (60), Expect = 9.8 Identities = 24/65 (36%), Positives = 25/65 (38%), Gaps = 15/65 (23%) Query: 63 PPPPPPLGGTLGARAPAAWA------------PASVLLERGVLALPP-PLPGGAVPPAPR 109 PP PPP A+ P A P L RG PP P P AV AP Sbjct: 1247 PPLPPPAEERTSAKGPETMASKFPSSSSDWRVPGQGLENRGEPPTPPSPAPAPAV--APG 1304 Query: 110 GSSAS 114 GSS S Sbjct: 1305 GSSES 1309 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 46.2 bits (108), Expect = 3e-05 Identities = 62/256 (24%), Positives = 94/256 (36%), Gaps = 29/256 (11%) Query: 11 PVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPP---- 66 P P+G + TP S ++P A ++ + S +G P + P PP Sbjct: 1212 PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATP 1271 Query: 67 PPLGGTL------GARAPAAWAPASVLLERGVLALPP---PLPGGAVPPAPRGSSASQEE 117 P L G L GA PA P S + G PP P P A PP+P+GS + Sbjct: 1272 PSLKGGLATPPHKGAPNPAVVTPPSP--KGGPATSPPKGAPTPPAATPPSPKGSPGTPPP 1329 Query: 118 QDEELDHILSPPP---MPFRKCSNPDVASGPGKSLKYKRQLSEDGRQLRRGSLGGALTGR 174 + ++PP P + P GP + +G G A+T Sbjct: 1330 KGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKG--GPAMTP- 1386 Query: 175 YLLPNPVAGQAWPA--SAETSNLVRMRSQALGQSAPSLTASLKELSLPRRGSLIDSQKWN 232 P+P G A P+ TS V S + AP+ + + + P +G L Sbjct: 1387 ---PSPKRGPAIPSPKGDPTSPAVIPLSP---KKAPATPVTREGAATPSKGDLTPPAVTP 1440 Query: 233 CLVKRPVCPNAGRTSP 248 +K+ +A + P Sbjct: 1441 VSLKKAPATSAPKGGP 1456 Score = 40.4 bits (93), Expect = 0.001 Identities = 35/132 (26%), Positives = 49/132 (37%), Gaps = 13/132 (9%) Query: 11 PVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEGEPG------GFSREHQPP 64 P P+G + TP S ++P A + S +G P G S Sbjct: 980 PSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAAT 1039 Query: 65 PPPPLGGTLGARAP--AAWAPASVLLE-RGVLALPP----PLPGGAVPPAPRGSSASQEE 117 PP P G P A PA+ L +G A P P P A PP+P+G A+ Sbjct: 1040 PPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSP 1099 Query: 118 QDEELDHILSPP 129 + + +PP Sbjct: 1100 KGAPMPPAATPP 1111 Score = 40.0 bits (92), Expect = 0.002 Identities = 36/132 (27%), Positives = 53/132 (40%), Gaps = 23/132 (17%) Query: 4 KVSEAPEPVPRGCSGHGSRTPASALVA-ASSPGASSAESSSGSETLSEEGEPGGFSREHQ 62 K S A P P+G S + TP S + A++P A ++ + S +G P S + Sbjct: 1020 KGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGA 1079 Query: 63 PPPPP-----PLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEE 117 P PP P GG PA +P P+P A PP+P+G A+ Sbjct: 1080 PTPPAATPPSPKGG------PATPSPKGA-----------PMPPAATPPSPKGGLATPPH 1122 Query: 118 QDEELDHILSPP 129 + +PP Sbjct: 1123 KGAPTTPAATPP 1134 Score = 35.8 bits (81), Expect = 0.036 Identities = 43/182 (23%), Positives = 60/182 (32%), Gaps = 25/182 (13%) Query: 11 PVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEG-----EPGGFSREHQPPP 65 P P+G + TP S ++P A ++ + S +G P G P Sbjct: 1097 PSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP 1156 Query: 66 PPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELDHI 125 P P GG A P AP + A PP GG P+P+G+ + Sbjct: 1157 PSPKGGL--ATPPPKGAPTTPA------ATPPSPKGGLATPSPKGAPTTP---------- 1198 Query: 126 LSPPPMPFRKCSNPDVASGPGKSLKYKRQLSEDGRQLRRGSLGGALTGRYLLPNPVAGQA 185 + PP P + P P + S G G T P+P G A Sbjct: 1199 AATPPSPKGGLATPSPKGAP--TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPA 1256 Query: 186 WP 187 P Sbjct: 1257 TP 1258 Score = 34.3 bits (77), Expect = 0.10 Identities = 39/138 (28%), Positives = 54/138 (39%), Gaps = 12/138 (8%) Query: 5 VSEAPEPVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPP 64 VS +P+ R + GS P + + SSP + S +LS +G + H P Sbjct: 799 VSVSPQ-TKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPT 857 Query: 65 PPPPLGGTLGARAPAAWAPASVLLERGVLALPP---PLPGGAVPPAPRGSSASQEEQDEE 121 PP P GA P+A P S +GV LPP P P P P+ A+ + Sbjct: 858 PPSP----KGAPTPSAVTPLS---PKGV-TLPPKETPTPSVVNLPFPKEGPATPAPKQAP 909 Query: 122 LDHILSPPPMPFRKCSNP 139 + S P R P Sbjct: 910 ALSMTSSSPKKARATPAP 927 Score = 33.1 bits (74), Expect = 0.23 Identities = 32/129 (24%), Positives = 43/129 (33%), Gaps = 20/129 (15%) Query: 4 KVSEAPEPVPRGCSGHGSRTPASALVAASSPGASS---AESSSGSETLSEEGEPGGFSRE 60 K + P V G TPA A S +SS A ++ + + P G Sbjct: 883 KETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTP 942 Query: 61 HQPPPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDE 120 PP P GG A WAP P A PP+P+G A+ + Sbjct: 943 PAATPPSPKGGP--ATPSPKWAPT---------------PPAATPPSPKGGPATPSPKGA 985 Query: 121 ELDHILSPP 129 +PP Sbjct: 986 PTPPAATPP 994 >gi|156104872 Ets2 repressor factor [Homo sapiens] Length = 548 Score = 45.8 bits (107), Expect = 3e-05 Identities = 48/158 (30%), Positives = 64/158 (40%), Gaps = 30/158 (18%) Query: 22 RTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPPPLGGTLGARAPA-- 79 + P + + P SSA SSS S + F + QPPP G +A A Sbjct: 347 KCPLPPMAPETPPVPSSASSSSSSSS-------SPFKFKLQPPPLGRRQRAAGEKAVAGA 399 Query: 80 --AWAPASVLLE-RGVLALPPPLPGGAVPPAPRGSS--------ASQEEQDEELDHILSP 128 + A L E G LA PPP P V P G S + ++E+D E+ Sbjct: 400 DKSGGSAGGLAEGAGALAPPPPPPQIKVEPISEGESEEVEVTDISDEDEEDGEVFKTPRA 459 Query: 129 PPMPFRKCSNPDVASGPGKS------LKYKRQLSEDGR 160 PP P P+ PG S L++KR+ SED R Sbjct: 460 PPAP----PKPEPGEAPGASQCMPLKLRFKRRWSEDCR 493 Score = 33.5 bits (75), Expect = 0.18 Identities = 36/107 (33%), Positives = 46/107 (42%), Gaps = 11/107 (10%) Query: 3 EKVSEAPEP-VPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSREH 61 E +S +P P CS S SA+VA S ++ S G+ SE EP G Sbjct: 151 EVLSPTEDPRSPPACSSSSSSL-FSAVVARRLGRGSVSDCSDGT---SELEEPLGEDPRA 206 Query: 62 QPPPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAP 108 +PP PP LG G P A P + GV + P GG P +P Sbjct: 207 RPPGPPDLGAFRG--PPLARLPH----DPGVFRVYPRPRGGPEPLSP 247 >gi|149999378 inverted formin 2 isoform 2 [Homo sapiens] Length = 1240 Score = 45.4 bits (106), Expect = 5e-05 Identities = 43/151 (28%), Positives = 59/151 (39%), Gaps = 14/151 (9%) Query: 7 EAPEPVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPP 66 E +P + +++ S P A ++S+ PG S E PPPP Sbjct: 384 EGQQPAAAAACEPVDHAQSESILKVSQPRALEQQASTPPPPPPPPLLPGS-SAEPPPPPP 442 Query: 67 PPLGGTLGARAPAAWAPASVLLERGVLA-----LPPPLPGGA--VPPAP-----RGSSAS 114 PP ++GA+A P L G +A LPPPLPG +PP P G Sbjct: 443 PPPLPSVGAKALPTAPPPPPLPGLGAMAPPAPPLPPPLPGSCEFLPPPPPPLPGLGCPPP 502 Query: 115 QEEQDEELDHILSPPPMPFRKCS-NPDVASG 144 + PPP P C+ +P VA G Sbjct: 503 PPPLLPGMGWGPPPPPPPLLPCTCSPPVAGG 533 >gi|149999380 inverted formin 2 isoform 1 [Homo sapiens] Length = 1249 Score = 45.4 bits (106), Expect = 5e-05 Identities = 43/151 (28%), Positives = 59/151 (39%), Gaps = 14/151 (9%) Query: 7 EAPEPVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPP 66 E +P + +++ S P A ++S+ PG S E PPPP Sbjct: 384 EGQQPAAAAACEPVDHAQSESILKVSQPRALEQQASTPPPPPPPPLLPGS-SAEPPPPPP 442 Query: 67 PPLGGTLGARAPAAWAPASVLLERGVLA-----LPPPLPGGA--VPPAP-----RGSSAS 114 PP ++GA+A P L G +A LPPPLPG +PP P G Sbjct: 443 PPPLPSVGAKALPTAPPPPPLPGLGAMAPPAPPLPPPLPGSCEFLPPPPPPLPGLGCPPP 502 Query: 115 QEEQDEELDHILSPPPMPFRKCS-NPDVASG 144 + PPP P C+ +P VA G Sbjct: 503 PPPLLPGMGWGPPPPPPPLLPCTCSPPVAGG 533 >gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] Length = 1263 Score = 45.1 bits (105), Expect = 6e-05 Identities = 35/103 (33%), Positives = 43/103 (41%), Gaps = 10/103 (9%) Query: 63 PPPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGG-AVPPAPRGSSASQEEQDEE 121 PPPPPPL G+ G P P E G+ PPPLPGG +PP P Sbjct: 679 PPPPPPLPGSAGIPPPPPPLPG----EAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPP 734 Query: 122 LDHILSPPPMPFRKCSNPDVASGPGKSLKYKRQLSEDGRQLRR 164 + PPP F + P + G YK ++ QLRR Sbjct: 735 GMGMPPPPPFGFGVPAAPVLPFGLTPKKLYKPEV-----QLRR 772 Score = 39.7 bits (91), Expect = 0.002 Identities = 35/113 (30%), Positives = 44/113 (38%), Gaps = 18/113 (15%) Query: 37 SSAESSSGSETLSEEGEPGGFSREHQPPPPPPLGGTLGARAPAAWAPASVLLERGVLALP 96 SS S G +S P S + PPPPPL +G +P++ + + P Sbjct: 619 SSPPSLPGGTAISP---PPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPP------P 669 Query: 97 PPLPGGA---VPPAPRGSSASQEEQDEELDHILSPPPMPFRKCSNPDVASGPG 146 PPLPG A PP P SA L PP P P + GPG Sbjct: 670 PPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPP------PPLPGGPG 716 Score = 36.6 bits (83), Expect = 0.021 Identities = 37/125 (29%), Positives = 44/125 (35%), Gaps = 28/125 (22%) Query: 24 PASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPPPLGGTLGARAPAAWAP 83 P S A P A SG+ + PG + PPPPPP P P Sbjct: 564 PPSVPSRAPVPPAPPLPGDSGT-IIPPPPAPGDSTTPPPPPPPPP---------PPPPLP 613 Query: 84 ASVLLERGVLALPPPLPGGAV--PPAPRGSSASQEEQDEELDHILSPPPMPFRKCSNPDV 141 V + PP LPGG PP P A+ I PPP+P P Sbjct: 614 GGVCISS-----PPSLPGGTAISPPPPLSGDAT----------IPPPPPLP-EGVGIPSP 657 Query: 142 ASGPG 146 +S PG Sbjct: 658 SSLPG 662 >gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] Length = 1272 Score = 45.1 bits (105), Expect = 6e-05 Identities = 35/103 (33%), Positives = 43/103 (41%), Gaps = 10/103 (9%) Query: 63 PPPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGG-AVPPAPRGSSASQEEQDEE 121 PPPPPPL G+ G P P E G+ PPPLPGG +PP P Sbjct: 688 PPPPPPLPGSAGIPPPPPPLPG----EAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPP 743 Query: 122 LDHILSPPPMPFRKCSNPDVASGPGKSLKYKRQLSEDGRQLRR 164 + PPP F + P + G YK ++ QLRR Sbjct: 744 GMGMPPPPPFGFGVPAAPVLPFGLTPKKLYKPEV-----QLRR 781 Score = 39.7 bits (91), Expect = 0.002 Identities = 35/113 (30%), Positives = 44/113 (38%), Gaps = 18/113 (15%) Query: 37 SSAESSSGSETLSEEGEPGGFSREHQPPPPPPLGGTLGARAPAAWAPASVLLERGVLALP 96 SS S G +S P S + PPPPPL +G +P++ + + P Sbjct: 628 SSPPSLPGGTAISP---PPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPP------P 678 Query: 97 PPLPGGA---VPPAPRGSSASQEEQDEELDHILSPPPMPFRKCSNPDVASGPG 146 PPLPG A PP P SA L PP P P + GPG Sbjct: 679 PPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPP------PPLPGGPG 725 Score = 36.6 bits (83), Expect = 0.021 Identities = 37/125 (29%), Positives = 44/125 (35%), Gaps = 28/125 (22%) Query: 24 PASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPPPLGGTLGARAPAAWAP 83 P S A P A SG+ + PG + PPPPPP P P Sbjct: 573 PPSVPSRAPVPPAPPLPGDSGT-IIPPPPAPGDSTTPPPPPPPPP---------PPPPLP 622 Query: 84 ASVLLERGVLALPPPLPGGAV--PPAPRGSSASQEEQDEELDHILSPPPMPFRKCSNPDV 141 V + PP LPGG PP P A+ I PPP+P P Sbjct: 623 GGVCISS-----PPSLPGGTAISPPPPLSGDAT----------IPPPPPLP-EGVGIPSP 666 Query: 142 ASGPG 146 +S PG Sbjct: 667 SSLPG 671 >gi|66932986 filamin-binding LIM protein-1 isoform b [Homo sapiens] Length = 374 Score = 45.1 bits (105), Expect = 6e-05 Identities = 42/144 (29%), Positives = 55/144 (38%), Gaps = 34/144 (23%) Query: 7 EAPEPVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPP 66 EAP P+ +TP + L SP + +++ + GG PPPP Sbjct: 44 EAPAPM---------KTPEAGLAGRPSPWTTPGRAAATVPAAPMQLFNGGC-----PPPP 89 Query: 67 PPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVP-----PAPRGSSASQEEQDEE 121 P L G VL + +L PPP P +P PAP G+S D E Sbjct: 90 PVLDGE------------DVLPDLDLLPPPPPPPPVLLPSEEEAPAPMGASLIA---DLE 134 Query: 122 LDHILSPPPMPFRKCSNPDVASGP 145 H+ PPP P P V GP Sbjct: 135 QLHLSPPPPPPQAPAEGPSVQPGP 158 >gi|66932982 filamin-binding LIM protein-1 isoform a [Homo sapiens] Length = 373 Score = 45.1 bits (105), Expect = 6e-05 Identities = 42/144 (29%), Positives = 55/144 (38%), Gaps = 34/144 (23%) Query: 7 EAPEPVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPP 66 EAP P+ +TP + L SP + +++ + GG PPPP Sbjct: 44 EAPAPM---------KTPEAGLAGRPSPWTTPGRAAATVPAAPMQLFNGGC-----PPPP 89 Query: 67 PPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVP-----PAPRGSSASQEEQDEE 121 P L G VL + +L PPP P +P PAP G+S D E Sbjct: 90 PVLDGE------------DVLPDLDLLPPPPPPPPVLLPSEEEAPAPMGASLIA---DLE 134 Query: 122 LDHILSPPPMPFRKCSNPDVASGP 145 H+ PPP P P V GP Sbjct: 135 QLHLSPPPPPPQAPAEGPSVQPGP 158 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 44.7 bits (104), Expect = 8e-05 Identities = 44/153 (28%), Positives = 57/153 (37%), Gaps = 16/153 (10%) Query: 8 APEPVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPP 67 AP P P SR+P+S L G SS+ +S+ E + P G + PP Sbjct: 608 APGPPPPP-----SRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPP--- 659 Query: 68 PLGGTLGARAPAAWA--PASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEE---- 121 L A PAAW+ PA L RG P P P P + G E + E Sbjct: 660 --DAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATP 717 Query: 122 LDHILSPPPMPFRKCSNPDVASGPGKSLKYKRQ 154 L P P P +G G S + +Q Sbjct: 718 APGALDPGPSPGTSGGKAAAGAGAGASSRSPKQ 750 Score = 32.3 bits (72), Expect = 0.40 Identities = 45/173 (26%), Positives = 61/173 (35%), Gaps = 21/173 (12%) Query: 8 APEPVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPP 67 AP P +G SR PAS A+ + ++ +S G G +R P P Sbjct: 74 APRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTR---PGPLG 130 Query: 68 PLGGTLGARAPAAWAPASVLLERGVLA------LPPPLPGGAVPPAPRGSSASQEEQDEE 121 G + A A A+ +R L+ P PG P R S A+ E Sbjct: 131 QKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE---- 186 Query: 122 LDHILSPPPMPFRKCSNPDVASGPGKSLKYKRQLS---EDGRQLRRGSLGGAL 171 + P P P + P GP KS+ + S RR S GG L Sbjct: 187 ---VGLPRPAPSARPRPP--TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGL 234 Score = 29.6 bits (65), Expect = 2.6 Identities = 29/89 (32%), Positives = 35/89 (39%), Gaps = 5/89 (5%) Query: 21 SRTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPPPLGGTLGARA-PA 79 S P+ + A SP AS S S T + P + Q PP PP + A P Sbjct: 441 SPPPSPPVQAPFSPPASPPVSPSA--TPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPP 498 Query: 80 AWAPASVLLERGVLALPPPL--PGGAVPP 106 AP + LA PPP P A PP Sbjct: 499 PQAPPPLAAPPLQLAKPPPQAPPALATPP 527 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 44.7 bits (104), Expect = 8e-05 Identities = 44/153 (28%), Positives = 57/153 (37%), Gaps = 16/153 (10%) Query: 8 APEPVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPP 67 AP P P SR+P+S L G SS+ +S+ E + P G + PP Sbjct: 877 APGPPPPP-----SRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPP--- 928 Query: 68 PLGGTLGARAPAAWA--PASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEE---- 121 L A PAAW+ PA L RG P P P P + G E + E Sbjct: 929 --DAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATP 986 Query: 122 LDHILSPPPMPFRKCSNPDVASGPGKSLKYKRQ 154 L P P P +G G S + +Q Sbjct: 987 APGALDPGPSPGTSGGKAAAGAGAGASSRSPKQ 1019 Score = 35.0 bits (79), Expect = 0.061 Identities = 31/110 (28%), Positives = 43/110 (39%), Gaps = 11/110 (10%) Query: 10 EPVP----RGCSGHGSRTPASALVAAS-----SPGAS--SAESSSGSETLSEEGEPGGFS 58 EP P R +G G + PAS +++S SP S SA + + + +P G Sbjct: 219 EPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQ 278 Query: 59 REHQPPPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAP 108 P PP A P + +P + G A P P P A P P Sbjct: 279 ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLP 328 Score = 32.3 bits (72), Expect = 0.40 Identities = 45/173 (26%), Positives = 61/173 (35%), Gaps = 21/173 (12%) Query: 8 APEPVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPP 67 AP P +G SR PAS A+ + ++ +S G G +R P P Sbjct: 74 APRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTR---PGPLG 130 Query: 68 PLGGTLGARAPAAWAPASVLLERGVLA------LPPPLPGGAVPPAPRGSSASQEEQDEE 121 G + A A A+ +R L+ P PG P R S A+ E Sbjct: 131 QKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE---- 186 Query: 122 LDHILSPPPMPFRKCSNPDVASGPGKSLKYKRQLS---EDGRQLRRGSLGGAL 171 + P P P + P GP KS+ + S RR S GG L Sbjct: 187 ---VGLPRPAPSARPRPP--TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGL 234 Score = 28.1 bits (61), Expect = 7.5 Identities = 16/44 (36%), Positives = 19/44 (43%), Gaps = 4/44 (9%) Query: 64 PPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPA 107 PP PPL L P+ AP S+ L PP P PP+ Sbjct: 332 PPSPPLATPLPLAPPSPSAPPSL----QTLPSPPATPPSQAPPS 371 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 44.7 bits (104), Expect = 8e-05 Identities = 44/153 (28%), Positives = 57/153 (37%), Gaps = 16/153 (10%) Query: 8 APEPVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPP 67 AP P P SR+P+S L G SS+ +S+ E + P G + PP Sbjct: 569 APGPPPPP-----SRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPP--- 620 Query: 68 PLGGTLGARAPAAWA--PASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEE---- 121 L A PAAW+ PA L RG P P P P + G E + E Sbjct: 621 --DAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATP 678 Query: 122 LDHILSPPPMPFRKCSNPDVASGPGKSLKYKRQ 154 L P P P +G G S + +Q Sbjct: 679 APGALDPGPSPGTSGGKAAAGAGAGASSRSPKQ 711 Score = 30.8 bits (68), Expect = 1.2 Identities = 34/129 (26%), Positives = 44/129 (34%), Gaps = 20/129 (15%) Query: 24 PASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPPPLGGTLGARAPAAWAP 83 P A P +SS ++ P PP PP T +P A Sbjct: 279 PRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQAT 338 Query: 84 ASVLLERGV--LALPPP-------LPGGAVPPAPRGS-------SASQEEQDEELDHIL- 126 S L + LA PPP LP PP+P S + S + + H+L Sbjct: 339 HSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ 398 Query: 127 ---SPPPMP 132 SPPP P Sbjct: 399 APFSPPPSP 407 Score = 29.6 bits (65), Expect = 2.6 Identities = 29/89 (32%), Positives = 35/89 (39%), Gaps = 5/89 (5%) Query: 21 SRTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPPPLGGTLGARA-PA 79 S P+ + A SP AS S S T + P + Q PP PP + A P Sbjct: 402 SPPPSPPVQAPFSPPASPPVSPSA--TPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPP 459 Query: 80 AWAPASVLLERGVLALPPPL--PGGAVPP 106 AP + LA PPP P A PP Sbjct: 460 PQAPPPLAAPPLQLAKPPPQAPPALATPP 488 >gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] Length = 1464 Score = 43.9 bits (102), Expect = 1e-04 Identities = 47/163 (28%), Positives = 58/163 (35%), Gaps = 29/163 (17%) Query: 2 GEKVSEAPEPVPRGCSGHGSRT-PASALVAASSPGASSAESSSGSETLSEEGEPGGFSRE 60 G + S P P G G R P A PG G + E P G E Sbjct: 863 GARGSAGP-PGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGE 921 Query: 61 HQPPPPPPLGGTLG-------ARAPAAWAPASVLLERGVLALP--------PPLPGGAVP 105 PP PP G G A AP P + +RGV+ LP P LPG + Sbjct: 922 VGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGE 981 Query: 106 PAPRGSSASQEEQDEELDHILSPPPMPFRKCSNPDVASGPGKS 148 P +G S + E+ PP P P +A PG+S Sbjct: 982 PGKQGPSGASGERG---------PPGPM---GPPGLAGPPGES 1012 Score = 39.3 bits (90), Expect = 0.003 Identities = 41/123 (33%), Positives = 51/123 (41%), Gaps = 20/123 (16%) Query: 2 GEKVSEAPEPVPRGCSGHGSRTPASALVAASSPGASSAESSSGSE-TLSEEGEPGGFSRE 60 GE+ S P P+G G R + L PGA S GS + G PG ++ Sbjct: 509 GERGSPGPAG-PKGSPGEAGRPGEAGL-----PGAKGLTGSPGSPGPDGKTGPPGPAGQD 562 Query: 61 HQPPPPPPLG-----GTLGARAP--AAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSA 113 +P PP P G G +G P AA P ERGV P P GAV PA + A Sbjct: 563 GRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKA-GERGV-----PGPPGAVGPAGKDGEA 616 Query: 114 SQE 116 + Sbjct: 617 GAQ 619 Score = 38.5 bits (88), Expect = 0.006 Identities = 43/153 (28%), Positives = 51/153 (33%), Gaps = 22/153 (14%) Query: 13 PRGCSGH-GSRTPASALVAASSPGASSAESSSGSE-TLSEEGEPGGFSREHQPPPPPPLG 70 P G SG G P A PG S E + G+E + +G PG + P P G Sbjct: 987 PSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPG 1046 Query: 71 GTLGARAPAAWAPASVLLERGVLALPPP--------LPGGAVPPAPRGSSASQEEQDEE- 121 AP PA +RG P G A P PRG EQ + Sbjct: 1047 APGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRG 1106 Query: 122 ---------LDHILSPPPMPFRKCSNPDVASGP 145 L PP P + P ASGP Sbjct: 1107 IKGHRGFSGLQGPPGPPGSPGEQ--GPSGASGP 1137 Score = 36.6 bits (83), Expect = 0.021 Identities = 42/121 (34%), Positives = 48/121 (39%), Gaps = 22/121 (18%) Query: 8 APEPV-PRGCSGHGSRT----PASAL--VAASSPGASSAESSSGSETLSEEGEPG----- 55 AP PV P G SG T PA + V A P ET E+G+ G Sbjct: 1053 APGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGET-GEQGDRGIKGHR 1111 Query: 56 GFSREHQPPPPPPLGGTLGARAPA-AWAPASVLLERGVLALPPP-----LPGGAVPPAPR 109 GFS PP PP G+ G + P+ A PA G P LPG PP PR Sbjct: 1112 GFSGLQGPPGPP---GSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPR 1168 Query: 110 G 110 G Sbjct: 1169 G 1169 Score = 32.3 bits (72), Expect = 0.40 Identities = 49/197 (24%), Positives = 65/197 (32%), Gaps = 38/197 (19%) Query: 11 PVPRGCSGHGSRTPASALVAASSP-------GASSAESSSGSETLSEEGEPGGFSREHQP 63 P P G G+ T A+ + P GA A+ +G + G G +P Sbjct: 316 PGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQ--GPRGSEGPQGVRGEP 373 Query: 64 PPPPPLGGTLGARAPAAWAPASVLLERGV--LALPPPLPGG---------AVPPAPRGSS 112 PP P G A P A G +A P PG PP P+G+S Sbjct: 374 GPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNS 433 Query: 113 ASQEEQDEELDHILSPPPMPFRKCSNPDVASGPGKSLKYKRQLSEDGRQLRRGSLGGALT 172 + D P P V PG + E+G++ RG G T Sbjct: 434 GEPGAPGSKGDTGAKGEPGPV------GVQGPPGPA-------GEEGKRGARGEPGP--T 478 Query: 173 GRYLLPNPVAGQAWPAS 189 G LP P + P S Sbjct: 479 G---LPGPPGERGGPGS 492 >gi|160707881 formin 2 [Homo sapiens] Length = 1722 Score = 43.9 bits (102), Expect = 1e-04 Identities = 46/164 (28%), Positives = 53/164 (32%), Gaps = 38/164 (23%) Query: 9 PEPVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPPP 68 P P P C+ S P +V P + T + P E PPPPPP Sbjct: 856 PSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQ-GTEMLPPPPPP 914 Query: 69 LGGT-------------------LGARAP-------AAWAPASVLLERGVLALPPPLPGG 102 L G GA P AA P L G+ LPPPLPG Sbjct: 915 LPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGI-PLPPPLPGA 973 Query: 103 AVPPAPRGSSASQEEQDEELDHILSPPPMPFRKCSNPDVASGPG 146 +PP P A I PPP+P P G G Sbjct: 974 GIPPPPPLPGAG----------IPPPPPLPGAGIPPPPPLPGAG 1007 Score = 43.5 bits (101), Expect = 2e-04 Identities = 30/86 (34%), Positives = 33/86 (38%), Gaps = 13/86 (15%) Query: 64 PPPPPLGGT---LGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDE 120 PPPPPL G L P A P L + PPPLPG +PP P A Sbjct: 954 PPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG------ 1007 Query: 121 ELDHILSPPPMPFRKCSNPDVASGPG 146 I PPP+P P G G Sbjct: 1008 ----IPPPPPLPGAGIPPPPPLPGAG 1029 Score = 41.2 bits (95), Expect = 9e-04 Identities = 26/69 (37%), Positives = 29/69 (42%), Gaps = 18/69 (26%) Query: 64 PPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELD 123 PPPPPL P A P L R + PPPLPG +PP P A Sbjct: 1130 PPPPPL--------PGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAG--------- 1172 Query: 124 HILSPPPMP 132 I PPP+P Sbjct: 1173 -IPPPPPLP 1180 Score = 40.8 bits (94), Expect = 0.001 Identities = 28/83 (33%), Positives = 31/83 (37%), Gaps = 18/83 (21%) Query: 64 PPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELD 123 PPPPPL P A P L + PPPLPG +PP P A Sbjct: 976 PPPPPL--------PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG--------- 1018 Query: 124 HILSPPPMPFRKCSNPDVASGPG 146 I PPP+P P G G Sbjct: 1019 -IPPPPPLPGAGIPPPPPLPGAG 1040 Score = 40.8 bits (94), Expect = 0.001 Identities = 28/83 (33%), Positives = 31/83 (37%), Gaps = 18/83 (21%) Query: 64 PPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELD 123 PPPPPL P A P L + PPPLPG +PP P A Sbjct: 987 PPPPPL--------PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG--------- 1029 Query: 124 HILSPPPMPFRKCSNPDVASGPG 146 I PPP+P P G G Sbjct: 1030 -IPPPPPLPGAGIPPPPPLPGAG 1051 Score = 40.8 bits (94), Expect = 0.001 Identities = 28/83 (33%), Positives = 31/83 (37%), Gaps = 18/83 (21%) Query: 64 PPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELD 123 PPPPPL P A P L + PPPLPG +PP P A Sbjct: 998 PPPPPL--------PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG--------- 1040 Query: 124 HILSPPPMPFRKCSNPDVASGPG 146 I PPP+P P G G Sbjct: 1041 -IPPPPPLPGAGIPPPPPLPGAG 1062 Score = 40.8 bits (94), Expect = 0.001 Identities = 28/83 (33%), Positives = 31/83 (37%), Gaps = 18/83 (21%) Query: 64 PPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELD 123 PPPPPL P A P L + PPPLPG +PP P A Sbjct: 1009 PPPPPL--------PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG--------- 1051 Query: 124 HILSPPPMPFRKCSNPDVASGPG 146 I PPP+P P G G Sbjct: 1052 -IPPPPPLPGAGIPPPPPLPGAG 1073 Score = 40.8 bits (94), Expect = 0.001 Identities = 28/83 (33%), Positives = 31/83 (37%), Gaps = 18/83 (21%) Query: 64 PPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELD 123 PPPPPL P A P L + PPPLPG +PP P A Sbjct: 1020 PPPPPL--------PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG--------- 1062 Query: 124 HILSPPPMPFRKCSNPDVASGPG 146 I PPP+P P G G Sbjct: 1063 -IPPPPPLPGAGIPPPPPLPGAG 1084 Score = 40.8 bits (94), Expect = 0.001 Identities = 28/83 (33%), Positives = 31/83 (37%), Gaps = 18/83 (21%) Query: 64 PPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELD 123 PPPPPL P A P L + PPPLPG +PP P A Sbjct: 1031 PPPPPL--------PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG--------- 1073 Query: 124 HILSPPPMPFRKCSNPDVASGPG 146 I PPP+P P G G Sbjct: 1074 -IPPPPPLPGAGIPPPPPLPGAG 1095 Score = 40.4 bits (93), Expect = 0.001 Identities = 28/83 (33%), Positives = 31/83 (37%), Gaps = 18/83 (21%) Query: 64 PPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELD 123 PPPPPL P A P L + PPPLPG +PP P A Sbjct: 1042 PPPPPL--------PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG--------- 1084 Query: 124 HILSPPPMPFRKCSNPDVASGPG 146 I PPP+P P G G Sbjct: 1085 -IPPPPPLPGAGIPPPPPLPGVG 1106 Score = 40.0 bits (92), Expect = 0.002 Identities = 28/83 (33%), Positives = 31/83 (37%), Gaps = 18/83 (21%) Query: 64 PPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELD 123 PPPPPL P A P L + PPPLPG +PP P A Sbjct: 1053 PPPPPL--------PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG--------- 1095 Query: 124 HILSPPPMPFRKCSNPDVASGPG 146 I PPP+P P G G Sbjct: 1096 -IPPPPPLPGVGIPPPPPLPGAG 1117 Score = 40.0 bits (92), Expect = 0.002 Identities = 27/86 (31%), Positives = 31/86 (36%), Gaps = 20/86 (23%) Query: 64 PPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELD 123 PPPPPL P A P L + PPPLPG +PP P L Sbjct: 1108 PPPPPL--------PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP------------PLP 1147 Query: 124 HILSPPPMPFRKCSNPDVASGPGKSL 149 + PPP P P PG + Sbjct: 1148 RVGIPPPPPLPGAGIPPPPPLPGAGI 1173 Score = 39.7 bits (91), Expect = 0.002 Identities = 28/83 (33%), Positives = 31/83 (37%), Gaps = 18/83 (21%) Query: 64 PPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELD 123 PPPPPL P A P L + PPPLPG +PP P A Sbjct: 1075 PPPPPL--------PGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAG--------- 1117 Query: 124 HILSPPPMPFRKCSNPDVASGPG 146 I PPP+P P G G Sbjct: 1118 -IPPPPPLPGAGIPPPPPLPGAG 1139 Score = 39.3 bits (90), Expect = 0.003 Identities = 27/83 (32%), Positives = 30/83 (36%), Gaps = 18/83 (21%) Query: 64 PPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELD 123 PPPPPL P A P L + PPPLPG +PP P Sbjct: 1064 PPPPPL--------PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVG--------- 1106 Query: 124 HILSPPPMPFRKCSNPDVASGPG 146 I PPP+P P G G Sbjct: 1107 -IPPPPPLPGAGIPPPPPLPGAG 1128 Score = 38.1 bits (87), Expect = 0.007 Identities = 27/86 (31%), Positives = 31/86 (36%), Gaps = 20/86 (23%) Query: 64 PPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELD 123 PPPPPL P A P L + PPPLPG +PP P L Sbjct: 1152 PPPPPL--------PGAGIPPPPPLPGAGIPPPPPLPGVGIPPPP------------PLP 1191 Query: 124 HILSPPPMPFRKCSNPDVASGPGKSL 149 + PPP P P PG + Sbjct: 1192 GVGIPPPPPLPGAGIPPPPPLPGMGI 1217 Score = 37.0 bits (84), Expect = 0.016 Identities = 26/86 (30%), Positives = 30/86 (34%), Gaps = 20/86 (23%) Query: 64 PPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELD 123 PPPPPL P P L + PPPLPG +PP P L Sbjct: 1141 PPPPPL--------PRVGIPPPPPLPGAGIPPPPPLPGAGIPPPP------------PLP 1180 Query: 124 HILSPPPMPFRKCSNPDVASGPGKSL 149 + PPP P P PG + Sbjct: 1181 GVGIPPPPPLPGVGIPPPPPLPGAGI 1206 Score = 36.6 bits (83), Expect = 0.021 Identities = 19/45 (42%), Positives = 21/45 (46%), Gaps = 8/45 (17%) Query: 64 PPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAP 108 PPPPPL P P L + PPPLPG +PPAP Sbjct: 1185 PPPPPL--------PGVGIPPPPPLPGAGIPPPPPLPGMGIPPAP 1221 Score = 36.2 bits (82), Expect = 0.028 Identities = 27/83 (32%), Positives = 30/83 (36%), Gaps = 18/83 (21%) Query: 64 PPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELD 123 PPPPPL P A P L + PPPLP +PP P A Sbjct: 1119 PPPPPL--------PGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAG--------- 1161 Query: 124 HILSPPPMPFRKCSNPDVASGPG 146 I PPP+P P G G Sbjct: 1162 -IPPPPPLPGAGIPPPPPLPGVG 1183 Score = 33.1 bits (74), Expect = 0.23 Identities = 32/125 (25%), Positives = 40/125 (32%), Gaps = 39/125 (31%) Query: 62 QPPPPPPLGGTLGARAPAAWAPASVLLE-------------------------------- 89 QPPPPP L + G P + P S+ E Sbjct: 809 QPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSS 868 Query: 90 -----RGVLALPPPLPGGAVPPAPRGSSASQEEQDEELDHILSPPPMPFRKCSNPDVASG 144 V PPPLPG VP P S+A + + +L PPP P P Sbjct: 869 SMPGLGMVPPPPPPLPGMTVPTLP--STAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPL 926 Query: 145 PGKSL 149 PG + Sbjct: 927 PGAGI 931 Score = 28.1 bits (61), Expect = 7.5 Identities = 17/45 (37%), Positives = 18/45 (40%), Gaps = 15/45 (33%) Query: 64 PPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAP 108 PPPPPL G APA P P PG +PP P Sbjct: 1207 PPPPPLPGMGIPPAPAP---------------PLPPPGTGIPPPP 1236 Score = 27.7 bits (60), Expect = 9.8 Identities = 24/93 (25%), Positives = 34/93 (36%), Gaps = 1/93 (1%) Query: 30 AASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPPPLGGTLGARAPAAWAPASVLLE 89 A +PG+ E + + + E QPP P L + PAA A Sbjct: 260 AGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPS 319 Query: 90 RGVLALPPPLPGGAVPPAP-RGSSASQEEQDEE 121 P PG AP RG+ + EE +E+ Sbjct: 320 STAFPFPEAGPGEEAAGAPVRGAGDTDEEGEED 352 >gi|56549694 enabled homolog isoform a [Homo sapiens] Length = 591 Score = 43.1 bits (100), Expect = 2e-04 Identities = 52/157 (33%), Positives = 68/157 (43%), Gaps = 33/157 (21%) Query: 23 TPASALV---AASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPPPLGGTLGARAPA 79 TP ++++ +AS PG +A S +ET S++G G PPPPPPL P Sbjct: 275 TPLNSVLGDSSASEPGLQAA--SQPAETPSQQGIVLG---PLAPPPPPPL--------PP 321 Query: 80 AWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELDHILSPPPMPFRKCSNP 139 A ASV ALPPP PG PP + L + + PPP P + P Sbjct: 322 GPAQASV-------ALPPP-PGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPP--PPAPP 371 Query: 140 DVASGPGKSLKYKRQLSEDGRQLRRGSLGGALTGRYL 176 ASG + +SED R L L A+ G L Sbjct: 372 LPASG-----FFLASMSEDNRPLT--GLAAAIAGAKL 401 >gi|39930375 enabled homolog isoform b [Homo sapiens] Length = 570 Score = 43.1 bits (100), Expect = 2e-04 Identities = 52/157 (33%), Positives = 68/157 (43%), Gaps = 33/157 (21%) Query: 23 TPASALV---AASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPPPLGGTLGARAPA 79 TP ++++ +AS PG +A S +ET S++G G PPPPPPL P Sbjct: 275 TPLNSVLGDSSASEPGLQAA--SQPAETPSQQGIVLG---PLAPPPPPPL--------PP 321 Query: 80 AWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELDHILSPPPMPFRKCSNP 139 A ASV ALPPP PG PP + L + + PPP P + P Sbjct: 322 GPAQASV-------ALPPP-PGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPP--PPAPP 371 Query: 140 DVASGPGKSLKYKRQLSEDGRQLRRGSLGGALTGRYL 176 ASG + +SED R L L A+ G L Sbjct: 372 LPASG-----FFLASMSEDNRPLT--GLAAAIAGAKL 401 >gi|24431935 reticulon 4 isoform A [Homo sapiens] Length = 1192 Score = 43.1 bits (100), Expect = 2e-04 Identities = 39/127 (30%), Positives = 56/127 (44%), Gaps = 20/127 (15%) Query: 23 TPASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPPPLGGTLGARAPAAWA 82 +P S+ V A SP +++A S S L E+ EP +PPPPPP ++ +A W Sbjct: 111 SPVSSTVPAPSPLSAAAVSPS---KLPEDDEPPA-----RPPPPPP--ASVSPQAEPVWT 160 Query: 83 PASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELDHILSPPPMPFRKCSNPDVA 142 P + A PP P P RGSS S +E L + P+ N D+ Sbjct: 161 PPA-----PAPAAPPSTPAA---PKRRGSSGSVDETLFALP--AASEPVIRSSAENMDLK 210 Query: 143 SGPGKSL 149 PG ++ Sbjct: 211 EQPGNTI 217 Score = 27.7 bits (60), Expect = 9.8 Identities = 20/65 (30%), Positives = 25/65 (38%), Gaps = 1/65 (1%) Query: 68 PLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELDHILS 127 P G A P A A + L++ G PP P G +P AP + Q D Sbjct: 59 PAAGLSAAPVPTAPAAGAPLMDFGN-DFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTV 117 Query: 128 PPPMP 132 P P P Sbjct: 118 PAPSP 122 >gi|39812378 RAN binding protein 9 [Homo sapiens] Length = 729 Score = 42.4 bits (98), Expect = 4e-04 Identities = 35/118 (29%), Positives = 42/118 (35%), Gaps = 21/118 (17%) Query: 24 PASALVAASSPGASSAESSSGSETLSEEGEPGGFSRE----HQPPPPPPLGGTLGARAPA 79 P S +V + P S+ S +GS GE G + H PPPPPP P Sbjct: 29 PVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAAAALLLHPPPPPPPATAAPPPPPPP 88 Query: 80 AWAPASVLLERGVLALPP-----PLPGGAVP------------PAPRGSSASQEEQDE 120 PAS PP P P G P P P G SA E++ E Sbjct: 89 PPPPASAAAPASGPPAPPGLAAGPGPAGGAPTPALVAGSSAAAPFPHGDSALNEQEKE 146 Score = 37.4 bits (85), Expect = 0.012 Identities = 27/75 (36%), Positives = 31/75 (41%), Gaps = 8/75 (10%) Query: 62 QPPPPPPLGGT----LGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEE 117 QPPPPPP L PAA AP S + VL PP + G+ P G A E Sbjct: 4 QPPPPPPQQQQQQQQLSPPPPAALAPVSGV----VLPAPPAVSAGSSPAGSPGGGAGGEG 59 Query: 118 QDEELDHILSPPPMP 132 +L PP P Sbjct: 60 LGAAAAALLLHPPPP 74 >gi|169213924 PREDICTED: leucine rich repeat containing 68 [Homo sapiens] Length = 625 Score = 42.4 bits (98), Expect = 4e-04 Identities = 44/143 (30%), Positives = 56/143 (39%), Gaps = 33/143 (23%) Query: 1 MGEKVSEAPEPVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEGE----PGG 56 M E + P+P +G + P+ A SP + S S G E EEGE P G Sbjct: 487 MPETTATEPQPDDEPAAGVQNGAPSPA----PSPDSDSDSDSDGEEEEEEEGERDETPSG 542 Query: 57 F-------SREHQPPPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPR 109 S E QPPP PP G P P LALPP P G P + Sbjct: 543 AIDTRDTGSSEPQPPPEPPRS---GPPLPNGLKP------EFALALPPEPPPG---PEVK 590 Query: 110 GSSASQEEQ------DEELDHIL 126 G S E + ++EL+ +L Sbjct: 591 GGSCGLEHELSCSKNEKELEELL 613 >gi|169214345 PREDICTED: leucine rich repeat containing 68 [Homo sapiens] Length = 625 Score = 42.4 bits (98), Expect = 4e-04 Identities = 44/143 (30%), Positives = 56/143 (39%), Gaps = 33/143 (23%) Query: 1 MGEKVSEAPEPVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEGE----PGG 56 M E + P+P +G + P+ A SP + S S G E EEGE P G Sbjct: 487 MPETTATEPQPDDEPAAGVQNGAPSPA----PSPDSDSDSDSDGEEEEEEEGERDETPSG 542 Query: 57 F-------SREHQPPPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPR 109 S E QPPP PP G P P LALPP P G P + Sbjct: 543 AIDTRDTGSSEPQPPPEPPRS---GPPLPNGLKP------EFALALPPEPPPG---PEVK 590 Query: 110 GSSASQEEQ------DEELDHIL 126 G S E + ++EL+ +L Sbjct: 591 GGSCGLEHELSCSKNEKELEELL 613 >gi|169213302 PREDICTED: leucine rich repeat containing 68 [Homo sapiens] Length = 625 Score = 42.4 bits (98), Expect = 4e-04 Identities = 44/143 (30%), Positives = 56/143 (39%), Gaps = 33/143 (23%) Query: 1 MGEKVSEAPEPVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEGE----PGG 56 M E + P+P +G + P+ A SP + S S G E EEGE P G Sbjct: 487 MPETTATEPQPDDEPAAGVQNGAPSPA----PSPDSDSDSDSDGEEEEEEEGERDETPSG 542 Query: 57 F-------SREHQPPPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPR 109 S E QPPP PP G P P LALPP P G P + Sbjct: 543 AIDTRDTGSSEPQPPPEPPRS---GPPLPNGLKP------EFALALPPEPPPG---PEVK 590 Query: 110 GSSASQEEQ------DEELDHIL 126 G S E + ++EL+ +L Sbjct: 591 GGSCGLEHELSCSKNEKELEELL 613 >gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Homo sapiens] Length = 305 Score = 42.0 bits (97), Expect = 5e-04 Identities = 48/163 (29%), Positives = 63/163 (38%), Gaps = 16/163 (9%) Query: 24 PASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPPPLGGTLGARAPA-AWA 82 P + VA S P +AES G E E+ PPP P+ A APA A Sbjct: 97 PVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAA 156 Query: 83 PASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELDHILSPPPMPFRKCSNPDVA 142 P + + VLA P P P A PAP +A +P P P PD A Sbjct: 157 PVAAPVAVAVLA-PAPAPAPAPAPAPAPVAAPAPAPAP------APAPAP-APAPAPDAA 208 Query: 143 SGPGKSLKYKRQLSEDGRQLRRGSLGGALTGRYLLPNPVAGQA 185 P +S + + G++ L ++GR P AG A Sbjct: 209 --PQESAEQGANQGQRGQEPLADQLHSGISGR-----PAAGTA 244 >gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Homo sapiens] Length = 305 Score = 42.0 bits (97), Expect = 5e-04 Identities = 48/163 (29%), Positives = 63/163 (38%), Gaps = 16/163 (9%) Query: 24 PASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPPPLGGTLGARAPA-AWA 82 P + VA S P +AES G E E+ PPP P+ A APA A Sbjct: 97 PVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAA 156 Query: 83 PASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELDHILSPPPMPFRKCSNPDVA 142 P + + VLA P P P A PAP +A +P P P PD A Sbjct: 157 PVAAPVAVAVLA-PAPAPAPAPAPAPAPVAAPAPAPAP------APAPAP-APAPAPDAA 208 Query: 143 SGPGKSLKYKRQLSEDGRQLRRGSLGGALTGRYLLPNPVAGQA 185 P +S + + G++ L ++GR P AG A Sbjct: 209 --PQESAEQGANQGQRGQEPLADQLHSGISGR-----PAAGTA 244 >gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo sapiens] Length = 316 Score = 42.0 bits (97), Expect = 5e-04 Identities = 48/163 (29%), Positives = 63/163 (38%), Gaps = 16/163 (9%) Query: 24 PASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPPPLGGTLGARAPA-AWA 82 P + VA S P +AES G E E+ PPP P+ A APA A Sbjct: 108 PVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAA 167 Query: 83 PASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELDHILSPPPMPFRKCSNPDVA 142 P + + VLA P P P A PAP +A +P P P PD A Sbjct: 168 PVAAPVAVAVLA-PAPAPAPAPAPAPAPVAAPAPAPAP------APAPAP-APAPAPDAA 219 Query: 143 SGPGKSLKYKRQLSEDGRQLRRGSLGGALTGRYLLPNPVAGQA 185 P +S + + G++ L ++GR P AG A Sbjct: 220 --PQESAEQGANQGQRGQEPLADQLHSGISGR-----PAAGTA 255 >gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] Length = 1466 Score = 41.6 bits (96), Expect = 7e-04 Identities = 44/165 (26%), Positives = 57/165 (34%), Gaps = 24/165 (14%) Query: 11 PVPRGCSGHGSRTPASALVAASSPGASSAESS----SGSETLSEEGEPGGFSREHQPPPP 66 P P+G G T + PG ++ G + L G P G +P P Sbjct: 602 PGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPG--ENGKPGEP 659 Query: 67 PPLGGTLGARAPAAWAPASVLLERGV--LALPPPLPGGAVPPAPRGSSASQEEQDEELDH 124 P G AP A ERG LA P L GGA PP P G + Sbjct: 660 GPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGA---------- 709 Query: 125 ILSPPPMPFRKCSNPDVASGPGKSLKYKRQLSEDGRQLRRGSLGG 169 + PP P P + PG+ + L G + +G GG Sbjct: 710 --AGPPGPPGAAGTPGLQGMPGE----RGGLGSPGPKGDKGEPGG 748 Score = 37.7 bits (86), Expect = 0.009 Identities = 31/107 (28%), Positives = 43/107 (40%), Gaps = 20/107 (18%) Query: 11 PVPRGCSGH-GSRTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPPPL 69 P P G +G GS + A SPG++ A G E P G + PP PP + Sbjct: 335 PGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRG------EPGPQGHAGAQGPPGPPGI 388 Query: 70 GGTLGARAPAAWAPASVLLERGVLALP--PPLPGGAVPPAPRGSSAS 114 G+ G + E G +P P L G PP P G++ + Sbjct: 389 NGSPGGKG-----------EMGPAGIPGAPGLMGARGPPGPAGANGA 424 Score = 33.9 bits (76), Expect = 0.14 Identities = 39/137 (28%), Positives = 47/137 (34%), Gaps = 18/137 (13%) Query: 2 GEKVSEAPEPVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLS-EEGEPG--GFS 58 GEK S + P G A A PG S G + + E G+PG G S Sbjct: 930 GEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLS 989 Query: 59 REHQPPPP---PPLGGTLGARA----------PAAWAPASVLLERGVLALP--PPLPGGA 103 E PP P P L GT G P +RG P P PG Sbjct: 990 GERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHP 1049 Query: 104 VPPAPRGSSASQEEQDE 120 PP P G + ++ E Sbjct: 1050 GPPGPVGPAGKSGDRGE 1066 Score = 32.0 bits (71), Expect = 0.52 Identities = 48/189 (25%), Positives = 56/189 (29%), Gaps = 36/189 (19%) Query: 8 APEPVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPP 67 A P P+G G R AA PGA GS G PG + PP Sbjct: 851 AGPPGPQGVKGE--RGSPGGPGAAGFPGARGLPGPPGSN--GNPGPPGPSGSPGKDGPPG 906 Query: 68 PLGGTLGARAPAAWAP---------------------------ASVLLERGVLALPPPLP 100 P G T +P P A + RG LA PP +P Sbjct: 907 PAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARG-LAGPPGMP 965 Query: 101 GGAVPPAPRGSSASQEEQDEELDHILSPPPMPFRKCSNPDVASGPGKSLKYKRQLSEDGR 160 G P P+G + PP P A PG+ DG Sbjct: 966 GPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRD----GNPGSDGL 1021 Query: 161 QLRRGSLGG 169 R GS GG Sbjct: 1022 PGRDGSPGG 1030 Score = 29.6 bits (65), Expect = 2.6 Identities = 35/133 (26%), Positives = 43/133 (32%), Gaps = 32/133 (24%) Query: 7 EAPEPVPRGCSGH-GSRTPASALVAASSPGASSAESSSGSETL-------------SEEG 52 E+ +P G SG G P A + G + + GS+ L E G Sbjct: 979 ESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENG 1038 Query: 53 EPGGFSREHQPPPPPPLG-----GTLGARAPA--AWAPASVLLERGVLALPPPLPGGAVP 105 PG P PP P+G G G PA A AP P G P Sbjct: 1039 SPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPG-----------PAGSRGAPGP 1087 Query: 106 PAPRGSSASQEEQ 118 PRG E+ Sbjct: 1088 QGPRGDKGETGER 1100 Score = 29.6 bits (65), Expect = 2.6 Identities = 32/110 (29%), Positives = 39/110 (35%), Gaps = 7/110 (6%) Query: 8 APEPV-PRGCSGHGSRTPASALVA----ASSPGASSAESSSGSETLSEEGEPGGFSREHQ 62 AP P PRG G A+ + +PGA + +G + P G Sbjct: 1084 APGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVG 1143 Query: 63 PPPPPPLGGTLGARAP-AAWAPASVLLERGVLALPPPLPGGAVPPAPRGS 111 P PP GT G P P ERG P PG PP P G+ Sbjct: 1144 PSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEG-SPGHPGQPGPPGPPGA 1192 Score = 29.3 bits (64), Expect = 3.4 Identities = 35/117 (29%), Positives = 41/117 (35%), Gaps = 19/117 (16%) Query: 8 APEPV-PRGCSGHGSRTPASALVAASS-PGASSAESSSGSETLSEEGEPGGFSREHQPPP 65 AP P PRG +G R PG+ S G + G PG +P P Sbjct: 511 APGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDG-----KPGPPGSQGESGRPGP 565 Query: 66 PPPLG-----GTLGARAPAA--WAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQ 115 P P G G +G P AP ERG P PG PP G + Q Sbjct: 566 PGPSGPRGQPGVMGFPGPKGNDGAPGK-NGERG----GPGGPGPQGPPGKNGETGPQ 617 >gi|47519490 reticulon 4 isoform D [Homo sapiens] Length = 392 Score = 41.6 bits (96), Expect = 7e-04 Identities = 33/95 (34%), Positives = 45/95 (47%), Gaps = 18/95 (18%) Query: 23 TPASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPPPLGGTLGARAPAAWA 82 +P S+ V A SP +++A S S L E+ EP +PPPPPP ++ +A W Sbjct: 111 SPVSSTVPAPSPLSAAAVSPS---KLPEDDEPPA-----RPPPPPP--ASVSPQAEPVWT 160 Query: 83 PASVLLERGVLALPPPLPGGAVPPAPRGSSASQEE 117 P + A PP P P RGSS S +E Sbjct: 161 PPA-----PAPAAPPSTPAA---PKRRGSSGSVDE 187 Score = 27.7 bits (60), Expect = 9.8 Identities = 20/65 (30%), Positives = 25/65 (38%), Gaps = 1/65 (1%) Query: 68 PLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELDHILS 127 P G A P A A + L++ G PP P G +P AP + Q D Sbjct: 59 PAAGLSAAPVPTAPAAGAPLMDFGN-DFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTV 117 Query: 128 PPPMP 132 P P P Sbjct: 118 PAPSP 122 >gi|239754138 PREDICTED: hypothetical protein [Homo sapiens] Length = 274 Score = 40.8 bits (94), Expect = 0.001 Identities = 41/148 (27%), Positives = 52/148 (35%), Gaps = 24/148 (16%) Query: 34 PGASSAESSSGSETLSEEGEPGGFSREHQPPPPPPLGG--TLGARAPAA-----WAPASV 86 PG S S S P +PPPPPP LGAR A A S Sbjct: 42 PGPPSRSRSPSSRLKLPADPPRALPGSPEPPPPPPPAAPHVLGARVAAGPTHRLSASHSR 101 Query: 87 LLERGVLALPPPLPG----------GAVPPAPRGSSASQEEQDEELDHILSPPPMPFRKC 136 + RG + P PG A P +PR +A PPP P R Sbjct: 102 VSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRARAARAISNQSS-----PPPPPPSRAR 156 Query: 137 SNPDVASGPGKSLKYKRQLSEDGRQLRR 164 S S PG ++ + + + +LRR Sbjct: 157 SRSLRLSAPGS--RHDAEKASERNRLRR 182 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.309 0.129 0.388 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 14,142,191 Number of Sequences: 37866 Number of extensions: 967421 Number of successful extensions: 10917 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 232 Number of HSP's successfully gapped in prelim test: 1114 Number of HSP's that attempted gapping in prelim test: 6873 Number of HSP's gapped (non-prelim): 3630 length of query: 250 length of database: 18,247,518 effective HSP length: 100 effective length of query: 150 effective length of database: 14,460,918 effective search space: 2169137700 effective search space used: 2169137700 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.