Search of human proteins with 33413400

Search of human proteins with 33413400

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|33413400 esterase D/formylglutathione hydrolase [Homo
sapiens]
         (282 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|33413400 esterase D/formylglutathione hydrolase [Homo sapiens]     598   e-171
gi|85787627 dipeptidyl peptidase 10 isoform short [Homo sapiens]       34   0.13 
gi|52426756 dipeptidyl peptidase 10 isoform long [Homo sapiens]        34   0.13 
gi|83745141 bubblegum-related acyl-CoA synthetase 2 [Homo sapiens]     32   0.48 
gi|16933540 fibroblast activation protein, alpha subunit [Homo s...    31   1.4  
gi|117676384 splicing factor, arginine/serine-rich 2, interactin...    30   1.8  
gi|139394621 chondroitin sulfate proteoglycan 5 (neuroglycan C) ...    30   3.1  
gi|51242953 monoglyceride lipase isoform 2 [Homo sapiens]              29   4.1  
gi|6005786 monoglyceride lipase isoform 1 [Homo sapiens]               29   4.1  
gi|5453920 pancreatic lipase-related protein 1 [Homo sapiens]          29   5.3  
gi|22202619 cathepsin L1 preproprotein [Homo sapiens]                  28   6.9  
gi|4503155 cathepsin L1 preproprotein [Homo sapiens]                   28   6.9  
gi|53729352 WD repeat-containing protein 1 isoform 2 [Homo sapiens]    28   9.0  
gi|9257257 WD repeat-containing protein 1 isoform 1 [Homo sapiens]     28   9.0  

>gi|33413400 esterase D/formylglutathione hydrolase [Homo sapiens]
          Length = 282

 Score =  598 bits (1542), Expect = e-171
 Identities = 282/282 (100%), Positives = 282/282 (100%)

Query: 1   MALKQISSNKCFGGLQKVFEHDSVELNCKMKFAVYLPPKAETGKCPALYWLSGLTCTEQN 60
           MALKQISSNKCFGGLQKVFEHDSVELNCKMKFAVYLPPKAETGKCPALYWLSGLTCTEQN
Sbjct: 1   MALKQISSNKCFGGLQKVFEHDSVELNCKMKFAVYLPPKAETGKCPALYWLSGLTCTEQN 60

Query: 61  FISKSGYHQSASEHGLVVIAPDTSPRGCNIKGEDESWDFGTGAGFYVDATEDPWKTNYRM 120
           FISKSGYHQSASEHGLVVIAPDTSPRGCNIKGEDESWDFGTGAGFYVDATEDPWKTNYRM
Sbjct: 61  FISKSGYHQSASEHGLVVIAPDTSPRGCNIKGEDESWDFGTGAGFYVDATEDPWKTNYRM 120

Query: 121 YSYVTEELPQLINANFPVDPQRMSIFGHSMGGHGALICALKNPGKYKSVSAFAPICNPVL 180
           YSYVTEELPQLINANFPVDPQRMSIFGHSMGGHGALICALKNPGKYKSVSAFAPICNPVL
Sbjct: 121 YSYVTEELPQLINANFPVDPQRMSIFGHSMGGHGALICALKNPGKYKSVSAFAPICNPVL 180

Query: 181 CPWGKKAFSGYLGTDQSKWKAYDATHLVKSYPGSQLDILIDQGKDDQFLLDGQLLPDNFI 240
           CPWGKKAFSGYLGTDQSKWKAYDATHLVKSYPGSQLDILIDQGKDDQFLLDGQLLPDNFI
Sbjct: 181 CPWGKKAFSGYLGTDQSKWKAYDATHLVKSYPGSQLDILIDQGKDDQFLLDGQLLPDNFI 240

Query: 241 AACTEKKIPVVFRLQEGYDHSYYFIATFITDHIRHHAKYLNA 282
           AACTEKKIPVVFRLQEGYDHSYYFIATFITDHIRHHAKYLNA
Sbjct: 241 AACTEKKIPVVFRLQEGYDHSYYFIATFITDHIRHHAKYLNA 282


>gi|85787627 dipeptidyl peptidase 10 isoform short [Homo sapiens]
          Length = 789

 Score = 34.3 bits (77), Expect = 0.13
 Identities = 29/91 (31%), Positives = 43/91 (47%), Gaps = 5/91 (5%)

Query: 138 VDPQRMSIFGHSMGGHGALICALKNPGKYKSVSAFAPICNPVLCPWGKKAFS-GYLGTDQ 196
           +D +R+SIFG   GG+ A +    +   +K  S  API +  L      AFS  YLG   
Sbjct: 633 IDSKRLSIFGKGYGGYIASMILKSDEKLFKCGSVVAPITDLKLY---ASAFSERYLGMPS 689

Query: 197 SKWKAYDATHLVKSYPG-SQLDILIDQGKDD 226
            +   Y A  ++ +  G  + +ILI  G  D
Sbjct: 690 KEESTYQAASVLHNVHGLKEENILIIHGTAD 720


>gi|52426756 dipeptidyl peptidase 10 isoform long [Homo sapiens]
          Length = 796

 Score = 34.3 bits (77), Expect = 0.13
 Identities = 29/91 (31%), Positives = 43/91 (47%), Gaps = 5/91 (5%)

Query: 138 VDPQRMSIFGHSMGGHGALICALKNPGKYKSVSAFAPICNPVLCPWGKKAFS-GYLGTDQ 196
           +D +R+SIFG   GG+ A +    +   +K  S  API +  L      AFS  YLG   
Sbjct: 640 IDSKRLSIFGKGYGGYIASMILKSDEKLFKCGSVVAPITDLKLY---ASAFSERYLGMPS 696

Query: 197 SKWKAYDATHLVKSYPG-SQLDILIDQGKDD 226
            +   Y A  ++ +  G  + +ILI  G  D
Sbjct: 697 KEESTYQAASVLHNVHGLKEENILIIHGTAD 727


>gi|83745141 bubblegum-related acyl-CoA synthetase 2 [Homo sapiens]
          Length = 666

 Score = 32.3 bits (72), Expect = 0.48
 Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 5/77 (6%)

Query: 180 LCPWGKKAFSGYLGTDQSKWKAYDATHLVKSYPGSQLD---ILIDQGKDDQFLL--DGQL 234
           +C WG+  F GYL ++    +A D    + S    QLD    L   G   + L+   G+ 
Sbjct: 464 ICLWGRHIFMGYLESETETTEAIDDEGWLHSGDLGQLDGLGFLYVTGHIKEILITAGGEN 523

Query: 235 LPDNFIAACTEKKIPVV 251
           +P   +    +KKIP++
Sbjct: 524 VPPIPVETLVKKKIPII 540


>gi|16933540 fibroblast activation protein, alpha subunit [Homo
           sapiens]
          Length = 760

 Score = 30.8 bits (68), Expect = 1.4
 Identities = 40/162 (24%), Positives = 68/162 (41%), Gaps = 23/162 (14%)

Query: 17  KVFEHDSVELNCKMKFAVYLPPKAETGK-CPALYWLSGLTCTE--QNFISKSGYHQSASE 73
           K  E D + L  KM     LPP+ +  K  P L  + G  C++  ++  + +     AS+
Sbjct: 509 KKLEVDEITLWYKM----ILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASK 564

Query: 74  HGLVVIAPDTSPRGCNIKGEDESWDFGTGAGFYVDATEDPWKTNYRMYSYVTEELPQLIN 133
            G+V+   D   RG   +G+   +      G Y    ED               + + I 
Sbjct: 565 EGMVIALVDG--RGTAFQGDKLLYAVYRKLGVY--EVEDQ-----------ITAVRKFIE 609

Query: 134 ANFPVDPQRMSIFGHSMGGHGALICALKNPGKYKSVSAFAPI 175
             F +D +R++I+G S GG+ + +      G +K   A AP+
Sbjct: 610 MGF-IDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPV 650


>gi|117676384 splicing factor, arginine/serine-rich 2, interacting
            protein [Homo sapiens]
          Length = 1463

 Score = 30.4 bits (67), Expect = 1.8
 Identities = 38/164 (23%), Positives = 65/164 (39%), Gaps = 22/164 (13%)

Query: 4    KQISSNKCFGGLQ--KVFEHDSVELNCKMKFAVYLPPKAETGKCPALYWL--SGLTCTEQ 59
            K +S N    G +  K  E  S +   + +F+ +  P   +G   A  W     L    Q
Sbjct: 1101 KPLSGNSNSSGSESFKFVEQQSYKRKSEQEFS-FDTPADRSGWTSASSWAVRKTLPADVQ 1159

Query: 60   NFISKSGYHQSASEHGLVVIAPDTSPRGCNIKGEDESWDFGTGAGFYVDATEDPWKTNYR 119
            N+ S+ G + S  + G +    +TS +  ++K +             VD ++ P      
Sbjct: 1160 NYYSRRGRNSSGPQSGWMKQEEETSGQDSSLKDQTNQ---------QVDGSQLP----IN 1206

Query: 120  MYSYVTEELPQLINANFPVDPQRMSIFGHSMGGHGALICALKNP 163
            M       + Q +NA      Q M+IF + +G H  L+   +NP
Sbjct: 1207 MMQPQMNVMQQQMNAQH----QPMNIFPYPVGVHAPLMNIQRNP 1246


>gi|139394621 chondroitin sulfate proteoglycan 5 (neuroglycan C)
           precursor [Homo sapiens]
          Length = 539

 Score = 29.6 bits (65), Expect = 3.1
 Identities = 14/40 (35%), Positives = 18/40 (45%)

Query: 177 NPVLCPWGKKAFSGYLGTDQSKWKAYDATHLVKSYPGSQL 216
           N +L P GK       G   S+W A    H + S PGS +
Sbjct: 298 NELLVPTGKPGLGPGTGQPTSRWHAVPPQHTLGSVPGSSI 337


>gi|51242953 monoglyceride lipase isoform 2 [Homo sapiens]
          Length = 303

 Score = 29.3 bits (64), Expect = 4.1
 Identities = 11/31 (35%), Positives = 19/31 (61%)

Query: 145 IFGHSMGGHGALICALKNPGKYKSVSAFAPI 175
           + GHSMGG  A++ A + PG +  +   +P+
Sbjct: 118 LLGHSMGGAIAILTAAERPGHFAGMVLISPL 148


>gi|6005786 monoglyceride lipase isoform 1 [Homo sapiens]
          Length = 313

 Score = 29.3 bits (64), Expect = 4.1
 Identities = 11/31 (35%), Positives = 19/31 (61%)

Query: 145 IFGHSMGGHGALICALKNPGKYKSVSAFAPI 175
           + GHSMGG  A++ A + PG +  +   +P+
Sbjct: 128 LLGHSMGGAIAILTAAERPGHFAGMVLISPL 158


>gi|5453920 pancreatic lipase-related protein 1 [Homo sapiens]
          Length = 467

 Score = 28.9 bits (63), Expect = 5.3
 Identities = 14/56 (25%), Positives = 24/56 (42%)

Query: 109 ATEDPWKTNYRMYSYVTEELPQLINANFPVDPQRMSIFGHSMGGHGALICALKNPG 164
           AT      N R+      ++  ++   +   P ++ + GHS+G H A     K PG
Sbjct: 131 ATYTQAANNVRVVGAQVAQMLDILLTEYSYPPSKVHLIGHSLGAHVAGEAGSKTPG 186


>gi|22202619 cathepsin L1 preproprotein [Homo sapiens]
          Length = 333

 Score = 28.5 bits (62), Expect = 6.9
 Identities = 23/90 (25%), Positives = 35/90 (38%), Gaps = 7/90 (7%)

Query: 35  YLPPKAETGKCPALYWLSGLTCTEQNFISKSGYHQSASEHGLVVIAPDTSPRGCNIKGED 94
           Y+ P    G+C + +  S     E     K+G   S SE  LV  +      GCN    D
Sbjct: 125 YVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMD 184

Query: 95  ESWDFGTGAG-------FYVDATEDPWKTN 117
            ++ +    G       +  +ATE+  K N
Sbjct: 185 YAFQYVQDNGGLDSEESYPYEATEESCKYN 214


>gi|4503155 cathepsin L1 preproprotein [Homo sapiens]
          Length = 333

 Score = 28.5 bits (62), Expect = 6.9
 Identities = 23/90 (25%), Positives = 35/90 (38%), Gaps = 7/90 (7%)

Query: 35  YLPPKAETGKCPALYWLSGLTCTEQNFISKSGYHQSASEHGLVVIAPDTSPRGCNIKGED 94
           Y+ P    G+C + +  S     E     K+G   S SE  LV  +      GCN    D
Sbjct: 125 YVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMD 184

Query: 95  ESWDFGTGAG-------FYVDATEDPWKTN 117
            ++ +    G       +  +ATE+  K N
Sbjct: 185 YAFQYVQDNGGLDSEESYPYEATEESCKYN 214


>gi|53729352 WD repeat-containing protein 1 isoform 2 [Homo sapiens]
          Length = 466

 Score = 28.1 bits (61), Expect = 9.0
 Identities = 53/214 (24%), Positives = 72/214 (33%), Gaps = 50/214 (23%)

Query: 92  GEDESWDFGTGAGFYVDATEDPWKTNYRMYSYVTEELPQLINANFPVDPQRMSIFGHSMG 151
           G    WD  TG     D+      TN ++     +E  QLI+ +     +  S+      
Sbjct: 204 GHINYWDSETGEN---DSFAGKGHTN-QVSRMTVDESGQLISCSMDDTVRYTSLMLRDYS 259

Query: 152 GHGALI------CALKNPGKYKSVSAFAPICNPVLCPWGKKAFS----GYL--------G 193
           G G +       C    PG Y  V     I   VL    +K FS    GY         G
Sbjct: 260 GQGVVKLDVQPKCVAVGPGGYAVVVCIGQI---VLLKDQRKCFSIDNPGYEPEVVAVHPG 316

Query: 194 TDQSKWKAYDATHLVKSYPGSQLDILIDQGK---------DDQFLLDGQLLPDNFIAACT 244
            D       D    + S  G+ L    D+GK         D  +  DG      F+A C 
Sbjct: 317 GDTVAIGGVDGNVRLYSILGTTLK---DEGKLLEAKGPVTDVAYSHDGA-----FLAVCD 368

Query: 245 EKKIPVVFRLQEGYDHSYYFIATFITDHIRHHAK 278
             K+  VF + +GY  +  F          HHAK
Sbjct: 369 ASKVVTVFSVADGYSENNVFYG--------HHAK 394


>gi|9257257 WD repeat-containing protein 1 isoform 1 [Homo sapiens]
          Length = 606

 Score = 28.1 bits (61), Expect = 9.0
 Identities = 53/214 (24%), Positives = 72/214 (33%), Gaps = 50/214 (23%)

Query: 92  GEDESWDFGTGAGFYVDATEDPWKTNYRMYSYVTEELPQLINANFPVDPQRMSIFGHSMG 151
           G    WD  TG     D+      TN ++     +E  QLI+ +     +  S+      
Sbjct: 344 GHINYWDSETGEN---DSFAGKGHTN-QVSRMTVDESGQLISCSMDDTVRYTSLMLRDYS 399

Query: 152 GHGALI------CALKNPGKYKSVSAFAPICNPVLCPWGKKAFS----GYL--------G 193
           G G +       C    PG Y  V     I   VL    +K FS    GY         G
Sbjct: 400 GQGVVKLDVQPKCVAVGPGGYAVVVCIGQI---VLLKDQRKCFSIDNPGYEPEVVAVHPG 456

Query: 194 TDQSKWKAYDATHLVKSYPGSQLDILIDQGK---------DDQFLLDGQLLPDNFIAACT 244
            D       D    + S  G+ L    D+GK         D  +  DG      F+A C 
Sbjct: 457 GDTVAIGGVDGNVRLYSILGTTLK---DEGKLLEAKGPVTDVAYSHDGA-----FLAVCD 508

Query: 245 EKKIPVVFRLQEGYDHSYYFIATFITDHIRHHAK 278
             K+  VF + +GY  +  F          HHAK
Sbjct: 509 ASKVVTVFSVADGYSENNVFYG--------HHAK 534


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.438 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,837,430
Number of Sequences: 37866
Number of extensions: 543800
Number of successful extensions: 976
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 966
Number of HSP's gapped (non-prelim): 14
length of query: 282
length of database: 18,247,518
effective HSP length: 101
effective length of query: 181
effective length of database: 14,423,052
effective search space: 2610572412
effective search space used: 2610572412
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.