Guide to the Human Genome
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Search of human proteins with 33286446

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|33286446 opioid growth factor receptor [Homo sapiens]
         (677 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|33286446 opioid growth factor receptor [Homo sapiens]             1413   0.0  
gi|55770902 opioid growth factor receptor-like 1 [Homo sapiens]       273   4e-73
gi|150170670 piccolo isoform 2 [Homo sapiens]                          91   3e-18
gi|150378539 piccolo isoform 1 [Homo sapiens]                          91   3e-18
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      89   1e-17
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     88   2e-17
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H...    85   3e-16
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...    82   1e-15
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...    82   1e-15
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...    82   1e-15
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]          81   4e-15
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...    80   8e-15
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...    80   8e-15
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...    80   8e-15
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    80   8e-15
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]       79   2e-14
gi|239745501 PREDICTED: similar to acyl-CoA synthetase medium-ch...    79   2e-14
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     77   4e-14
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    77   7e-14
gi|87196339 collagen, type VI, alpha 1 precursor [Homo sapiens]        77   7e-14
gi|157074225 nuclear pore complex interacting protein-like 3 [Ho...    76   9e-14
gi|139394646 iroquois homeobox protein 5 [Homo sapiens]                75   2e-13
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             75   3e-13
gi|62000702 diacylglycerol kinase kappa [Homo sapiens]                 74   3e-13
gi|48762934 alpha 2 type I collagen [Homo sapiens]                     74   4e-13
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      74   4e-13
gi|163965366 nascent polypeptide-associated complex alpha subuni...    73   8e-13
gi|169211436 PREDICTED: hypothetical protein [Homo sapiens]            72   2e-12
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    71   3e-12
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    71   3e-12

>gi|33286446 opioid growth factor receptor [Homo sapiens]
          Length = 677

 Score = 1413 bits (3658), Expect = 0.0
 Identities = 677/677 (100%), Positives = 677/677 (100%)

Query: 1   MDDPDCDSTWEEDEEDAEDAEDEDCEDGEAAGARDADAGDEDEESEEPRAARPSSFQSRM 60
           MDDPDCDSTWEEDEEDAEDAEDEDCEDGEAAGARDADAGDEDEESEEPRAARPSSFQSRM
Sbjct: 1   MDDPDCDSTWEEDEEDAEDAEDEDCEDGEAAGARDADAGDEDEESEEPRAARPSSFQSRM 60

Query: 61  TGSRNWRATRDMCRYRHNYPDLVERDCNGDTPNLSFYRNEIRFLPNGCFIEDILQNWTDN 120
           TGSRNWRATRDMCRYRHNYPDLVERDCNGDTPNLSFYRNEIRFLPNGCFIEDILQNWTDN
Sbjct: 61  TGSRNWRATRDMCRYRHNYPDLVERDCNGDTPNLSFYRNEIRFLPNGCFIEDILQNWTDN 120

Query: 121 YDLLEDNHSYIQWLFPLREPGVNWHAKPLTLREVEVFKSSQEIQERLVRAYELMLGFYGI 180
           YDLLEDNHSYIQWLFPLREPGVNWHAKPLTLREVEVFKSSQEIQERLVRAYELMLGFYGI
Sbjct: 121 YDLLEDNHSYIQWLFPLREPGVNWHAKPLTLREVEVFKSSQEIQERLVRAYELMLGFYGI 180

Query: 181 RLEDRGTGTVGRAQNYQKRFQNLNWRSHNNLRITRILKSLGELGLEHFQAPLVRFFLEET 240
           RLEDRGTGTVGRAQNYQKRFQNLNWRSHNNLRITRILKSLGELGLEHFQAPLVRFFLEET
Sbjct: 181 RLEDRGTGTVGRAQNYQKRFQNLNWRSHNNLRITRILKSLGELGLEHFQAPLVRFFLEET 240

Query: 241 LVRRELPGVRQSALDYFMFAVRCRHQRRQLVHFAWEHFRPRCKFVWGPQDKLRRFKPSSL 300
           LVRRELPGVRQSALDYFMFAVRCRHQRRQLVHFAWEHFRPRCKFVWGPQDKLRRFKPSSL
Sbjct: 241 LVRRELPGVRQSALDYFMFAVRCRHQRRQLVHFAWEHFRPRCKFVWGPQDKLRRFKPSSL 300

Query: 301 PHPLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLER 360
           PHPLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLER
Sbjct: 301 PHPLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLER 360

Query: 361 SQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALS 420
           SQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALS
Sbjct: 361 SQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALS 420

Query: 421 QGSLRTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLA 480
           QGSLRTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLA
Sbjct: 421 QGSLRTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLA 480

Query: 481 LAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSE 540
           LAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSE
Sbjct: 481 LAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSE 540

Query: 541 TPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSE 600
           TPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSE
Sbjct: 541 TPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSE 600

Query: 601 TPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEA 660
           TPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEA
Sbjct: 601 TPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEA 660

Query: 661 AELQDAEVESSAKSGKP 677
           AELQDAEVESSAKSGKP
Sbjct: 661 AELQDAEVESSAKSGKP 677


>gi|55770902 opioid growth factor receptor-like 1 [Homo sapiens]
          Length = 451

 Score =  273 bits (698), Expect = 4e-73
 Identities = 161/424 (37%), Positives = 233/424 (54%), Gaps = 43/424 (10%)

Query: 5   DCDSTWEEDEEDAEDA-------------EDEDCEDGEAAGARDADAGDEDEESEEPRAA 51
           DCDSTW+ D E   +               ++  +  E AG R   +   DE++E   A 
Sbjct: 18  DCDSTWQTDSEPEPEEPGPGGGSEGPGQESEQPAQPPEQAGGRPGASPAPDEDAEAAGAE 77

Query: 52  RPS-SFQSRMTGSRNWRATRDMCRYRHNYPDLVERDCNGDTPNLSFYRNEIRFLPNGCFI 110
           +   S ++     R++ A RD+ +YRH YP+  +     D  NL FY+N+I F P+G +I
Sbjct: 78  QGGDSTEATAKPKRSFYAARDLYKYRHQYPNFKDIRYQNDLSNLRFYKNKIPFKPDGVYI 137

Query: 111 EDILQNWTDNYDLLEDNHSYIQWLFPLREPGVNWHAKPLTLREVEVFKSSQEIQERLVRA 170
           E++L  W  +Y+ LE NH+YIQWLFPLRE G+N++AK LT  E+E FK ++E   R + A
Sbjct: 138 EEVLSKWKGDYEKLEHNHTYIQWLFPLREQGLNFYAKELTTYEIEEFKKTKEAIRRFLLA 197

Query: 171 YELMLGFYGIRLEDRGTGTVGRAQNYQKRFQNLNWRSHNNLRITRILKSLGELGLEHFQA 230
           Y++ML F+GI+L D+ TG V RA N+Q+RFQ+LN   HN LRITRILKSLGELG E F++
Sbjct: 198 YKMMLEFFGIKLTDK-TGNVARAVNWQERFQHLNESQHNYLRITRILKSLGELGYESFKS 256

Query: 231 PLVRFFLEETLVRRELPGVRQSALDYFMFAVRCRHQRRQLVHFAWEHFRPRCKFVWGPQD 290
           PLV+F L E LV   +P ++QSAL+YF++ +R R +RR+L+ FA +H+ P   F+WGP  
Sbjct: 257 PLVKFILHEALVENTIPNIKQSALEYFVYTIRDRRERRKLLRFAQKHYTPSENFIWGPPR 316

Query: 291 KLRRFKPSSLPHPLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRV---DEGPQP 347
           K             EGS K ++  SP    H + T       +       V    +  + 
Sbjct: 317 K----------EQSEGS-KAQKMSSPLASSHNSQTSMHKKAKDSKNSSSAVHLNSKTAED 365

Query: 348 RSVEPQDAGPLERSQGDEAGGHGEDRPEPLSPKE-SKKRKLEL-SRREQPPTEPGPQSAS 405
           + V P++  P+E +          DRP P    E +K R  E  S  E   ++P     +
Sbjct: 366 KKVAPKE--PVEET----------DRPSPEPSNEAAKPRNTEKDSNAENMNSQPEKTVTT 413

Query: 406 EVEK 409
             EK
Sbjct: 414 PTEK 417



 Score = 37.4 bits (85), Expect = 0.046
 Identities = 21/60 (35%), Positives = 28/60 (46%), Gaps = 5/60 (8%)

Query: 504 TEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG 563
           T+    P+E  PG  SE PG        ++PA+ P +  G   A PA DE AE+     G
Sbjct: 25  TDSEPEPEEPGPGGGSEGPGQE-----SEQPAQPPEQAGGRPGASPAPDEDAEAAGAEQG 79



 Score = 36.2 bits (82), Expect = 0.10
 Identities = 31/94 (32%), Positives = 42/94 (44%), Gaps = 15/94 (15%)

Query: 583 GPSPAGPTRDEPAESPSET---PGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPS 639
           G S   PT  E  +S  +T   P P   GP G       SE PG        ++PA+ P 
Sbjct: 7   GVSFREPTTVEDCDSTWQTDSEPEPEEPGPGGG------SEGPGQE-----SEQPAQPPE 55

Query: 640 ETPGPSPAGPTRDEPAKAGEAAELQDAEVESSAK 673
           +  G   A P  DE A+A  A +  D+  E++AK
Sbjct: 56  QAGGRPGASPAPDEDAEAAGAEQGGDS-TEATAK 88



 Score = 32.3 bits (72), Expect = 1.5
 Identities = 24/72 (33%), Positives = 31/72 (43%), Gaps = 12/72 (16%)

Query: 552 DEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAG 611
           D   ++ SE P P   GP G       SE PG        ++PA+ P +  G   A PA 
Sbjct: 20  DSTWQTDSE-PEPEEPGPGGG------SEGPGQES-----EQPAQPPEQAGGRPGASPAP 67

Query: 612 DEPAESPSETPG 623
           DE AE+     G
Sbjct: 68  DEDAEAAGAEQG 79



 Score = 32.3 bits (72), Expect = 1.5
 Identities = 21/62 (33%), Positives = 26/62 (41%), Gaps = 11/62 (17%)

Query: 522 PGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSET 581
           P P   GP G       SE PG        ++PA+ P +  G   A PA DE AE+    
Sbjct: 29  PEPEEPGPGGG------SEGPGQE-----SEQPAQPPEQAGGRPGASPAPDEDAEAAGAE 77

Query: 582 PG 583
            G
Sbjct: 78  QG 79



 Score = 32.0 bits (71), Expect = 1.9
 Identities = 26/84 (30%), Positives = 33/84 (39%), Gaps = 14/84 (16%)

Query: 523 GPSPAGPAGDEPAESPSET---PGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPS 579
           G S   P   E  +S  +T   P P   GP G       SE PG        ++PA+ P 
Sbjct: 7   GVSFREPTTVEDCDSTWQTDSEPEPEEPGPGGG------SEGPGQE-----SEQPAQPPE 55

Query: 580 ETPGPSPAGPTRDEPAESPSETPG 603
           +  G   A P  DE AE+     G
Sbjct: 56  QAGGRPGASPAPDEDAEAAGAEQG 79


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 91.3 bits (225), Expect = 3e-18
 Identities = 91/390 (23%), Positives = 151/390 (38%), Gaps = 36/390 (9%)

Query: 320 DHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGED-RPEPLS 378
           D EAS +  T   +  +      EG     ++ Q   P+ + QG       +D  P+ +S
Sbjct: 181 DSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSIS 240

Query: 379 PKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCA--LSQGSLRTGTQEVGGQDP 436
            ++ +K K +     +P   P     ++  K+ L  +       Q  +  G + V    P
Sbjct: 241 SQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRG-ESVKPSLP 299

Query: 437 GEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALA-----------GSP 485
             +  P +QP   +   +     K   G     A  SG  + LA             G+ 
Sbjct: 300 SPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTT 359

Query: 486 APSGHP----KAGHSENGVEEDTEGRTGPKE-----GTPGSPSETPGPSPAG-------- 528
            P   P    K    + G E+ +  + GPK      G   +P++ PGP+           
Sbjct: 360 KPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPK 419

Query: 529 PAGDEPA-ESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPA 587
           P   +P  +SP++ PGP         P + P++  GP         P + PS+ PGP+  
Sbjct: 420 PLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKP 479

Query: 588 GPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPA 647
            P +  PA+ P + PG   A P   +P  +      P PA P+  +P  +   +  P  A
Sbjct: 480 PPQQPGPAKPPPQQPG--SAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSA 537

Query: 648 GPTRDEPAKAGEAAELQDAEVESSAKSGKP 677
            P+  +P+ A  +A+ Q  +  S   SGKP
Sbjct: 538 KPSAQQPSPAKPSAQ-QSTKPVSQTGSGKP 566



 Score = 77.8 bits (190), Expect = 3e-14
 Identities = 84/370 (22%), Positives = 142/370 (38%), Gaps = 36/370 (9%)

Query: 306 GSRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERS---- 361
           G   ++++G+P     +   + ++  P    G G+  +GP           PL+R     
Sbjct: 226 GRDPLQQDGTPKSISSQQPEKIKSQPP----GTGKPIQGPTQTPQTDHAKLPLQRDASRP 281

Query: 362 QGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPG-----PQSASEVEKIALNLEG 416
           Q  +A     +  +P  P  SK    + +  + P  +PG     P  A    + +   + 
Sbjct: 282 QTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKP 341

Query: 417 CALSQGSLRTGTQEVGG-QDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGG 475
            A   G+++   Q  G  + P + + P + P     ++K    +   +       V    
Sbjct: 342 LAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTP 401

Query: 476 AQTLALAGSPAPS-GHPKAGHSENGVEEDTEG----RTGPKEGTPGS-PSETPGPSPAGP 529
           AQ    A  P    G PK    + G++   +     +T  ++  PG  P++  GP     
Sbjct: 402 AQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSA 461

Query: 530 AGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAES--PSETPGPSPA 587
               P + PS+ PGP    P    PA+ P + PG   A P   +P  +  P + PGP+  
Sbjct: 462 QQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPG--SAKPPSQQPGSTKPPPQQPGPAKP 519

Query: 588 GPTRDEPAESPSETPG--------PRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPS 639
            P +    + PS+ PG        P PA P+  +  +  S+T   +P  P    P  SPS
Sbjct: 520 SPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQP----PTVSPS 575

Query: 640 ETPGPSPAGP 649
               PS   P
Sbjct: 576 AKQPPSQGLP 585



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 84/356 (23%), Positives = 123/356 (34%), Gaps = 59/356 (16%)

Query: 345  PQPRSVEPQ-DAGPLERSQGDEAGGHGEDRPEPL--------SPKESKKRKLELSR--RE 393
            PQP+   P+ DA P +    D +      +P PL        SP    K+  E     + 
Sbjct: 677  PQPQQTSPKKDAAPKQ----DLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKP 732

Query: 394  QPPTEPGPQSASEVEKIA---------LNLEGCALSQGSLRTGTQEVGGQDPGEAVQPCR 444
             PP EP   S  +   +A         +      +S  S  T       +   +A +   
Sbjct: 733  APPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTT 792

Query: 445  QPLGARVADKVRKRRKVDEGAG--DSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEE 502
             PL    A   +      E     DS A+    + +  ++  P PS   K     + V++
Sbjct: 793  PPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIIS-HPGPSSESKGQKQVDPVQK 851

Query: 503  DTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRP-AGPAGDEPAESPSET 561
              E +   K  T  SP     P P G        SP+  PGPRP AG     P +SP   
Sbjct: 852  KEEPK---KAQTKMSPKPDAKPMPKG--------SPTP-PGPRPTAGQTVPTPQQSPKPQ 899

Query: 562  PGPRP----AGPAGDEPAESPSETPGPSPAGPTRDEPAE---------SPSETPGPRPAG 608
               R      G   D P   P+ TP  +  G      A          S +  PGP    
Sbjct: 900  EQSRRFSLNLGSITDAPKSQPT-TPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQS 958

Query: 609  PAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQ 664
              G    ++P+ +  P   GP    P  +    P P+ + P + E  KA  A +L+
Sbjct: 959  GPGAPMKQAPAPSQPPTSQGP----PKSTGQAPPAPAKSIPVKKE-TKAPAAEKLE 1009



 Score = 37.4 bits (85), Expect = 0.046
 Identities = 44/193 (22%), Positives = 73/193 (37%), Gaps = 15/193 (7%)

Query: 478 TLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAES 537
           T +     +P     +   +   ++D      PK+  P     T   SP+  A   P   
Sbjct: 668 TTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEAD 727

Query: 538 PSETPGP--RPAGPAGDEPAESPSETP-GPRPAGPAGDEPAESPSETPGPSPAGPTRDEP 594
               P P   P+ P+  + A    + P  P+   P  D  + S + T    P+   + + 
Sbjct: 728 SLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQA 787

Query: 595 AES---PSETPGPRPA---GPAGDEPAESPSETPGPRPAGPAG--DEPAESPSETPGPSP 646
            E    P +T   +P+    P G++ +   S+   PRPA  +     P  S SE+ G   
Sbjct: 788 EEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAI-PRPASDSKIISHPGPS-SESKGQKQ 845

Query: 647 AGPT--RDEPAKA 657
             P   ++EP KA
Sbjct: 846 VDPVQKKEEPKKA 858



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 60/284 (21%), Positives = 94/284 (33%), Gaps = 39/284 (13%)

Query: 345  PQPRSVEPQDAGPLERSQGDEAGGHGEDRPEP----LSPKESKKRKLELSR--REQPPTE 398
            P   + + Q+   LE+   D+A    E +P P    L P+E K R  E      E+ PT 
Sbjct: 1187 PMVTTDQKQEESKLEK---DKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTP 1243

Query: 399  PGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKR 458
               +   E +  A   +   L +  ++   +++ G+   + VQ  +QP          K 
Sbjct: 1244 EDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQ--------TKM 1295

Query: 459  RKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSP 518
              +  G   S         T  +   P P    K    E G E+  +        +   P
Sbjct: 1296 EGLPSGTPQSLP-KEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQP 1354

Query: 519  SETPGPSPAGPAGDEPAESPSETPG---------------------PRPAGPAGDEPAES 557
                G S  G + D  + S  E P                        P+ P+     ES
Sbjct: 1355 KSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLES 1414

Query: 558  PSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSET 601
               +     A    DE +E  ++    SP  P   E  +S SET
Sbjct: 1415 TVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSET 1458



 Score = 31.6 bits (70), Expect = 2.5
 Identities = 19/62 (30%), Positives = 25/62 (40%), Gaps = 1/62 (1%)

Query: 569  PAGDEPAESPSETPGPSPAGP-TRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPA 627
            PA   P+ SPS +  P+   P  R    +  ++ P P P  P    P   P   P P P 
Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPT 2431

Query: 628  GP 629
             P
Sbjct: 2432 SP 2433


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 91.3 bits (225), Expect = 3e-18
 Identities = 91/390 (23%), Positives = 151/390 (38%), Gaps = 36/390 (9%)

Query: 320 DHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGED-RPEPLS 378
           D EAS +  T   +  +      EG     ++ Q   P+ + QG       +D  P+ +S
Sbjct: 181 DSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSIS 240

Query: 379 PKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCA--LSQGSLRTGTQEVGGQDP 436
            ++ +K K +     +P   P     ++  K+ L  +       Q  +  G + V    P
Sbjct: 241 SQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRG-ESVKPSLP 299

Query: 437 GEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALA-----------GSP 485
             +  P +QP   +   +     K   G     A  SG  + LA             G+ 
Sbjct: 300 SPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTT 359

Query: 486 APSGHP----KAGHSENGVEEDTEGRTGPKE-----GTPGSPSETPGPSPAG-------- 528
            P   P    K    + G E+ +  + GPK      G   +P++ PGP+           
Sbjct: 360 KPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPK 419

Query: 529 PAGDEPA-ESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPA 587
           P   +P  +SP++ PGP         P + P++  GP         P + PS+ PGP+  
Sbjct: 420 PLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKP 479

Query: 588 GPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPA 647
            P +  PA+ P + PG   A P   +P  +      P PA P+  +P  +   +  P  A
Sbjct: 480 PPQQPGPAKPPPQQPG--SAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSA 537

Query: 648 GPTRDEPAKAGEAAELQDAEVESSAKSGKP 677
            P+  +P+ A  +A+ Q  +  S   SGKP
Sbjct: 538 KPSAQQPSPAKPSAQ-QSTKPVSQTGSGKP 566



 Score = 77.8 bits (190), Expect = 3e-14
 Identities = 84/370 (22%), Positives = 142/370 (38%), Gaps = 36/370 (9%)

Query: 306 GSRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERS---- 361
           G   ++++G+P     +   + ++  P    G G+  +GP           PL+R     
Sbjct: 226 GRDPLQQDGTPKSISSQQPEKIKSQPP----GTGKPIQGPTQTPQTDHAKLPLQRDASRP 281

Query: 362 QGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPG-----PQSASEVEKIALNLEG 416
           Q  +A     +  +P  P  SK    + +  + P  +PG     P  A    + +   + 
Sbjct: 282 QTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKP 341

Query: 417 CALSQGSLRTGTQEVGG-QDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGG 475
            A   G+++   Q  G  + P + + P + P     ++K    +   +       V    
Sbjct: 342 LAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTP 401

Query: 476 AQTLALAGSPAPS-GHPKAGHSENGVEEDTEG----RTGPKEGTPGS-PSETPGPSPAGP 529
           AQ    A  P    G PK    + G++   +     +T  ++  PG  P++  GP     
Sbjct: 402 AQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSA 461

Query: 530 AGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAES--PSETPGPSPA 587
               P + PS+ PGP    P    PA+ P + PG   A P   +P  +  P + PGP+  
Sbjct: 462 QQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPG--SAKPPSQQPGSTKPPPQQPGPAKP 519

Query: 588 GPTRDEPAESPSETPG--------PRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPS 639
            P +    + PS+ PG        P PA P+  +  +  S+T   +P  P    P  SPS
Sbjct: 520 SPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQP----PTVSPS 575

Query: 640 ETPGPSPAGP 649
               PS   P
Sbjct: 576 AKQPPSQGLP 585



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 84/356 (23%), Positives = 123/356 (34%), Gaps = 59/356 (16%)

Query: 345  PQPRSVEPQ-DAGPLERSQGDEAGGHGEDRPEPL--------SPKESKKRKLELSR--RE 393
            PQP+   P+ DA P +    D +      +P PL        SP    K+  E     + 
Sbjct: 677  PQPQQTSPKKDAAPKQ----DLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKP 732

Query: 394  QPPTEPGPQSASEVEKIA---------LNLEGCALSQGSLRTGTQEVGGQDPGEAVQPCR 444
             PP EP   S  +   +A         +      +S  S  T       +   +A +   
Sbjct: 733  APPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTT 792

Query: 445  QPLGARVADKVRKRRKVDEGAG--DSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEE 502
             PL    A   +      E     DS A+    + +  ++  P PS   K     + V++
Sbjct: 793  PPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIIS-HPGPSSESKGQKQVDPVQK 851

Query: 503  DTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRP-AGPAGDEPAESPSET 561
              E +   K  T  SP     P P G        SP+  PGPRP AG     P +SP   
Sbjct: 852  KEEPK---KAQTKMSPKPDAKPMPKG--------SPTP-PGPRPTAGQTVPTPQQSPKPQ 899

Query: 562  PGPRP----AGPAGDEPAESPSETPGPSPAGPTRDEPAE---------SPSETPGPRPAG 608
               R      G   D P   P+ TP  +  G      A          S +  PGP    
Sbjct: 900  EQSRRFSLNLGSITDAPKSQPT-TPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQS 958

Query: 609  PAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQ 664
              G    ++P+ +  P   GP    P  +    P P+ + P + E  KA  A +L+
Sbjct: 959  GPGAPMKQAPAPSQPPTSQGP----PKSTGQAPPAPAKSIPVKKE-TKAPAAEKLE 1009



 Score = 37.4 bits (85), Expect = 0.046
 Identities = 44/193 (22%), Positives = 73/193 (37%), Gaps = 15/193 (7%)

Query: 478 TLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAES 537
           T +     +P     +   +   ++D      PK+  P     T   SP+  A   P   
Sbjct: 668 TTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEAD 727

Query: 538 PSETPGP--RPAGPAGDEPAESPSETP-GPRPAGPAGDEPAESPSETPGPSPAGPTRDEP 594
               P P   P+ P+  + A    + P  P+   P  D  + S + T    P+   + + 
Sbjct: 728 SLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQA 787

Query: 595 AES---PSETPGPRPA---GPAGDEPAESPSETPGPRPAGPAG--DEPAESPSETPGPSP 646
            E    P +T   +P+    P G++ +   S+   PRPA  +     P  S SE+ G   
Sbjct: 788 EEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAI-PRPASDSKIISHPGPS-SESKGQKQ 845

Query: 647 AGPT--RDEPAKA 657
             P   ++EP KA
Sbjct: 846 VDPVQKKEEPKKA 858



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 60/284 (21%), Positives = 94/284 (33%), Gaps = 39/284 (13%)

Query: 345  PQPRSVEPQDAGPLERSQGDEAGGHGEDRPEP----LSPKESKKRKLELSR--REQPPTE 398
            P   + + Q+   LE+   D+A    E +P P    L P+E K R  E      E+ PT 
Sbjct: 1187 PMVTTDQKQEESKLEK---DKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTP 1243

Query: 399  PGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKR 458
               +   E +  A   +   L +  ++   +++ G+   + VQ  +QP          K 
Sbjct: 1244 EDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQ--------TKM 1295

Query: 459  RKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSP 518
              +  G   S         T  +   P P    K    E G E+  +        +   P
Sbjct: 1296 EGLPSGTPQSLP-KEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQP 1354

Query: 519  SETPGPSPAGPAGDEPAESPSETPG---------------------PRPAGPAGDEPAES 557
                G S  G + D  + S  E P                        P+ P+     ES
Sbjct: 1355 KSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLES 1414

Query: 558  PSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSET 601
               +     A    DE +E  ++    SP  P   E  +S SET
Sbjct: 1415 TVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSET 1458



 Score = 31.6 bits (70), Expect = 2.5
 Identities = 19/62 (30%), Positives = 25/62 (40%), Gaps = 1/62 (1%)

Query: 569  PAGDEPAESPSETPGPSPAGP-TRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPA 627
            PA   P+ SPS +  P+   P  R    +  ++ P P P  P    P   P   P P P 
Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPT 2431

Query: 628  GP 629
             P
Sbjct: 2432 SP 2433


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 89.0 bits (219), Expect = 1e-17
 Identities = 73/218 (33%), Positives = 95/218 (43%), Gaps = 28/218 (12%)

Query: 483 GSPAPSGHPKAGHSENGVEEDTEGRTGPK--EGTPGSPSETPGPSPAGPAGDEPAESPSE 540
           GSP P+G PK    E G   +  G  G K   G+PGSP       P GPAG +    P  
Sbjct: 512 GSPGPAG-PKGSPGEAGRPGEA-GLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPG 569

Query: 541 TPG----------PRPAGPAGDEPAESPSETPGPRPA-GPAGDEPAESPSETPGPSPAGP 589
            PG          P P G AG+         PGP  A GPAG +  E+ ++ P P PAGP
Sbjct: 570 PPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKD-GEAGAQGP-PGPAGP 627

Query: 590 TRDEPAESPSETPG----PRPAGPAGD--EPAES--PSETPGPRPAGPAGDE--PAESPS 639
             +   + P+ +PG    P PAGP G+  +P E   P +   P P+G  G+   P E   
Sbjct: 628 AGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGV 687

Query: 640 ETPGPSPAGPTRDEPAKAGEAAELQDAEVESSAKSGKP 677
           + P P PAGP     A   + A+       +    G P
Sbjct: 688 QGP-PGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAP 724



 Score = 75.9 bits (185), Expect = 1e-13
 Identities = 112/383 (29%), Positives = 134/383 (34%), Gaps = 47/383 (12%)

Query: 306 GSRKVEEEGSPGDPD-HEASTQGRTCGPEHSKGGGRVDEGPQ----PRSVEPQDAGPLER 360
           G+   E E  P  PD  E+ T   T G E  KG    D GP+    P     +D  P + 
Sbjct: 83  GAEVPEGECCPVCPDGSESPTDQETTGVEGPKG----DTGPRGPRGPAGPPGRDGIPGQP 138

Query: 361 SQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTE-PGPQSASEVEKIALNLEGCAL 419
                 G  G   P  L    + +       +       PGP   S          G   
Sbjct: 139 GLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPS-------GPRGLPG 191

Query: 420 SQGSLRTGTQEVGGQDPGEAVQP-CRQPLGARVADKVRKRRKVDEGAG------DSAAVA 472
             G+   G Q   G  PGE  +P    P+G R       +   D  AG      +     
Sbjct: 192 PPGA--PGPQGFQGP-PGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPG 248

Query: 473 SGGAQTL-ALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAG 531
             GA+ L   AG P   GH   G S     +   G  GPK G PGSP E   P   GP G
Sbjct: 249 PQGARGLPGTAGLPGMKGH--RGFSGLDGAKGDAGPAGPK-GEPGSPGENGAPGQMGPRG 305

Query: 532 DEPAESPSETPGPRPAGPAGDEPAESPSETPGPR-PAGPAGDEPAESPSETPGPSPAGPT 590
                     PG  PAG  G++ A   +  PGP  PAGP G   A       GP   GP 
Sbjct: 306 LPGERGRPGAPG--PAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQ--GPR 361

Query: 591 RDEPAESPSETPGP----RPAGPAGDEPAESPSETPG----PRPAGPAGDEPAESPSETP 642
             E  +     PGP      AGPAG+  A+      G    P  AG  G   A  PS   
Sbjct: 362 GSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQ 421

Query: 643 GP-SPAGP--TRDEPAKAGEAAE 662
           GP  P GP     EP   G   +
Sbjct: 422 GPGGPPGPKGNSGEPGAPGSKGD 444



 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 120/420 (28%), Positives = 153/420 (36%), Gaps = 96/420 (22%)

Query: 314 GSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGEDR 373
           G+PG P           GP   +G G    GP+  S EP   G    S+GD  G  GE  
Sbjct: 407 GAPGFPGAR--------GPSGPQGPGG-PPGPKGNSGEPGAPG----SKGD-TGAKGEPG 452

Query: 374 PEPLS--PKESKKRKLELSRREQPPTE-PGP--QSASEVEKIALNLEGCALSQGSL-RTG 427
           P  +   P  + +     +R E  PT  PGP  +      +     +G A  +G     G
Sbjct: 453 PVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERG 512

Query: 428 TQEVGGQ--DPGEAVQPCRQPL-GARVADKVRKRRKVDEGAGDSAAV------------- 471
           +    G    PGEA +P    L GA+           D   G                  
Sbjct: 513 SPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPG 572

Query: 472 ASGGAQTLALAGSPAPSGHP-KAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPA 530
           A G A  +   G    +G P KAG  E GV     G  GP  G  G       P PAGPA
Sbjct: 573 ARGQAGVMGFPGPKGAAGEPGKAG--ERGVP-GPPGAVGPA-GKDGEAGAQGPPGPAGPA 628

Query: 531 GDEPAESPSETPG----PRPAGPAGD--EPAES--PSETPGPRPAGPAGDE--PAESPSE 580
           G+   + P+ +PG    P PAGP G+  +P E   P +   P P+G  G+   P E   +
Sbjct: 629 GERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQ 688

Query: 581 TPGPSPAGPTR------DEPAESPSETPG----------------------PRPAGPAGD 612
            P P PAGP        ++ A+  +  PG                      P P G  GD
Sbjct: 689 GP-PGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGD 747

Query: 613 EPAESPSETPGPR----------PAGPAGDEPAESPSETPGPS-PAGPT--RDEPAKAGE 659
              +    +PG            P GPAG   A       GPS PAGPT  R  P   GE
Sbjct: 748 AGPKGADGSPGKDGVRGLTGPIGPPGPAG---APGDKGESGPSGPAGPTGARGAPGDRGE 804



 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 115/428 (26%), Positives = 139/428 (32%), Gaps = 134/428 (31%)

Query: 314  GSPGDPDHEASTQGRTCGPEHSKG----GGRVDE-GPQPRSVEPQDAGPLERSQGDEAGG 368
            G+PG      S      GP  + G     GRV   GP   +  P   GP  +  G   G 
Sbjct: 857  GAPGAKGARGSA-----GPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGK--GP 909

Query: 369  HGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGT 428
             GE  P          R  E+     PP  PGP      EK +   +G A + G+   G 
Sbjct: 910  RGETGPAG--------RPGEVG----PPGPPGPAG----EKGSPGADGPAGAPGT--PGP 951

Query: 429  QEVGGQD-----------------PGEAVQPCRQ-PLGARVADKVRKRRKVDEGAGDSAA 470
            Q + GQ                  PG + +P +Q P GA               +G+   
Sbjct: 952  QGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGA---------------SGERGP 996

Query: 471  VASGGAQTLALAGSPAPSGHPKAGHSENGVEED-------TEGRTGPKEGTPGSPSETPG 523
                G     LAG P  SG   A  +E     D         G TGP  G PG+P     
Sbjct: 997  PGPMGPP--GLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPA-GPPGAPGAPGA 1053

Query: 524  PSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPR------------------ 565
            P P GPAG   +    ET    PAGP G   A  P+   GPR                  
Sbjct: 1054 PGPVGPAGK--SGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHR 1111

Query: 566  -------PAGPAGDEPAESPSETPGPS-PAGPTRDEPAES---------PSETPGPRPAG 608
                   P GP G    + PS   GP+ P GP     A           P   PGPR  G
Sbjct: 1112 GFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPR--G 1169

Query: 609  PAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAG--------PTRDEPAKAGEA 660
              GD              AGP G      P   PGP  AG        P +++    G  
Sbjct: 1170 RTGD--------------AGPVGPPGPPGPPGPPGPPSAGFDFSFLPQPPQEKAHDGGRY 1215

Query: 661  AELQDAEV 668
                DA V
Sbjct: 1216 YRADDANV 1223



 Score = 69.7 bits (169), Expect = 8e-12
 Identities = 112/400 (28%), Positives = 133/400 (33%), Gaps = 71/400 (17%)

Query: 305 EGSRKVEEE----GSPGDPDHEASTQGR-------TCGPEHSKGGGRVDEGPQPRSVEPQ 353
           EG R    E    G PG P        R         GP+    G R   GP      P 
Sbjct: 466 EGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPK-GPAGERGSPGPAGPKGSPG 524

Query: 354 DAG-PLERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIAL 412
           +AG P E       G  G         K           R  PP  PG +  + V     
Sbjct: 525 EAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFP- 583

Query: 413 NLEGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVA 472
             +G A   G  + G + V G  P  AV P  +   A             E  G+     
Sbjct: 584 GPKGAAGEPG--KAGERGVPG--PPGAVGPAGKDGEAGAQGPPGPAGPAGE-RGEQGPAG 638

Query: 473 SGGAQTL-ALAGSPAPSGHPKAGHSENGVEEDTEGRTGP-----KEGTPGSPSETPGPSP 526
           S G Q L   AG P  +G P     E GV  D  G  GP     + G PG       P P
Sbjct: 639 SPGFQGLPGPAGPPGEAGKP----GEQGVPGDL-GAPGPSGARGERGFPGERGVQGPPGP 693

Query: 527 AGPAG------DEPAESPSETPG----------------------PRPAGPAGDEPAESP 558
           AGP G      ++ A+  +  PG                      P P G  GD   +  
Sbjct: 694 AGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGA 753

Query: 559 SETPGPR-------PAGPAGDEPAESPSETPGPS-PAGPTRDEPAESPSETPGPRPAGPA 610
             +PG         P GP G   A       GPS PAGPT    A  P +   P P GPA
Sbjct: 754 DGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGA--PGDRGEPGPPGPA 811

Query: 611 GDEPAESPSETPGPRPAGPAGDEPAESPSETPGPS-PAGP 649
           G   A  P     P   G  GD  A+  +  PGP+ PAGP
Sbjct: 812 GF--AGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGP 849



 Score = 69.7 bits (169), Expect = 8e-12
 Identities = 119/418 (28%), Positives = 139/418 (33%), Gaps = 103/418 (24%)

Query: 314 GSPGDPDHEAST--------QGRTC--GPEHSKGGGRVDEGPQPRSV--EPQDAGPL--- 358
           GSPG P  +  T         GR    GP  ++G   V   P P+    EP  AG     
Sbjct: 542 GSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVP 601

Query: 359 -------ERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPT-EPGPQSASEVEKI 410
                     +  EAG  G   P P  P           R EQ P   PG Q        
Sbjct: 602 GPPGAVGPAGKDGEAGAQGP--PGPAGPAGE--------RGEQGPAGSPGFQG------- 644

Query: 411 ALNLEGCALSQGSL-RTGTQEVGGQ--------------DPGE-AVQPCRQPLGARVADK 454
              L G A   G   + G Q V G                PGE  VQ    P G R A+ 
Sbjct: 645 ---LPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANG 701

Query: 455 VRKRRKVDEGAGDSAAVASGGAQTL-ALAGSPAPSGH-----PKAGHSENGVEEDTEGRT 508
                  D   GD+ A  + G+Q    L G P   G      PK    + G  +  +G  
Sbjct: 702 APGN---DGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAG-PKGADGSP 757

Query: 509 GPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPR-------------PAGPAGDEPA 555
           G K+G  G       P PAG  GD+    PS   GP              P GPAG    
Sbjct: 758 G-KDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGP 816

Query: 556 ESPSETPG----PRPAGPAGDEPAESPSETPG-PSPAGPTRDEPAESPSETPGPRPA--- 607
                 PG    P  AG  GD     P+   G P P G      A+    + GP  A   
Sbjct: 817 PGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGF 876

Query: 608 -GPAGDEPAESPSETPG-PRPAGPAGDE----------PAESPSETPGPSPAGPTRDE 653
            G AG      PS   G P P GPAG E          PA  P E   P P GP  ++
Sbjct: 877 PGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEK 934



 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 101/365 (27%), Positives = 126/365 (34%), Gaps = 48/365 (13%)

Query: 331 GPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGEDRPEPLSPKESKKRKLELS 390
           GP   +G       P P+  +     P E       G  G   P   +  + +  K    
Sbjct: 182 GPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRP 241

Query: 391 RREQPPTEPGPQSASEVEKIALNLEGCALSQG--SLRTGTQEVGGQDP-GEAVQPCRQPL 447
               PP   GPQ A  +   A  L G    +G   L     + G   P GE   P     
Sbjct: 242 GERGPP---GPQGARGLPGTA-GLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGA 297

Query: 448 GARVADKVRKRRKVDEGAGDSAAV-----ASGGAQTLALAGSPAPSGHPKA-GHSENGVE 501
             ++  +     +   GA   A       A+G A      G   P G P A G       
Sbjct: 298 PGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGP 357

Query: 502 EDTEGRTGPKEGTPGSPSETPGPS-PAGPAGDEPAESPSETPG----PRPAGPAGDEPAE 556
           +   G  GP +G  G P   PGP+  AGPAG+  A+      G    P  AG  G   A 
Sbjct: 358 QGPRGSEGP-QGVRGEPGP-PGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGAR 415

Query: 557 SPSETPGP-RPAGPAGD--EPAESPSE-------TPGP----SPAGPTRDEPAESPSETP 602
            PS   GP  P GP G+  EP    S+        PGP     P GP  +E        P
Sbjct: 416 GPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEP 475

Query: 603 GPRP-AGPAGDEPAESPSETPG----PRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKA 657
           GP    GP G+         PG      P GPAG        E   P PAGP +  P +A
Sbjct: 476 GPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAG--------ERGSPGPAGP-KGSPGEA 526

Query: 658 GEAAE 662
           G   E
Sbjct: 527 GRPGE 531



 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 76/254 (29%), Positives = 92/254 (36%), Gaps = 54/254 (21%)

Query: 463  EGAGDSAAV--ASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPK--EGTPGSP 518
            +GA  SA    A+G        G P PSG+  AG          EG  GP+   G  G P
Sbjct: 862  KGARGSAGPPGATGFPGAAGRVGPPGPSGN--AGPPGPPGPAGKEGGKGPRGETGPAGRP 919

Query: 519  SETPGPSPAGPAG-------DEPAESPSETPGPRPA----------------------GP 549
             E   P P GPAG       D PA +P  TPGP+                        GP
Sbjct: 920  GEVGPPGPPGPAGEKGSPGADGPAGAPG-TPGPQGIAGQRGVVGLPGQRGERGFPGLPGP 978

Query: 550  AGDEPAESPSETPG----PRPAGPAG--DEPAESPSETPGPSPAGPTRDEPAESPSETPG 603
            +G+   + PS   G    P P GP G    P ES  E    +   P RD    +  +   
Sbjct: 979  SGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGE 1038

Query: 604  PRPAGPAGDEPAESPSETPGPR-------PAGPAGDEPAESPSETPGPS-PAGPTRDEPA 655
              PAGP G   A       GP          GPAG      P    GP+ P GP  D+  
Sbjct: 1039 TGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDK-- 1096

Query: 656  KAGEAAELQDAEVE 669
              GE  E  D  ++
Sbjct: 1097 --GETGEQGDRGIK 1108



 Score = 66.2 bits (160), Expect = 9e-11
 Identities = 70/230 (30%), Positives = 85/230 (36%), Gaps = 45/230 (19%)

Query: 473  SGGAQTLALAGSPAPSGHP-KAGHSENGVEEDTEGRTGPK--EGTPGSPSETPGPSPAGP 529
            SG A      G+P   G P   G +        +G+ G K   G  G+  +   P PAGP
Sbjct: 787  SGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGP 846

Query: 530  AGDEPAESPSETPGPRPA-------------GPAGDEPAESPSETPG-PRPAGPAGDE-- 573
            AG          PG + A             G AG      PS   G P P GPAG E  
Sbjct: 847  AGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGG 906

Query: 574  --------PAESPSETPGPSPAGPTRDE---PAESPSETPG-PRPAGPAGDE-----PAE 616
                    PA  P E   P P GP  ++    A+ P+  PG P P G AG       P +
Sbjct: 907  KGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQ 966

Query: 617  SPSETPGPRPAGPAGDEPAESPSETPG----PSPAGPTRDEPAKAGEAAE 662
               E   P   GP+G+   + PS   G    P P GP    P  AG   E
Sbjct: 967  R-GERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGP----PGLAGPPGE 1011



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 54/175 (30%), Positives = 64/175 (36%), Gaps = 36/175 (20%)

Query: 515 PGSPSETPGPSPAGPAGDEP--------AESPSETPGPR----PAGPAGDEPAESPSETP 562
           PG+        P  P G E          E P    GPR    PAGP G +        P
Sbjct: 82  PGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLP 141

Query: 563 G-PRPAGPAG----------------DEPAESPSETPGPSPAGPTRDEPAESPSETPGPR 605
           G P P GP G                DE +      PG  P GP+       P   PGP+
Sbjct: 142 GPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPG--PMGPSGPRGLPGPPGAPGPQ 199

Query: 606 P-AGPAGDEPAESPSETP-GPR-PAGPAGDEPAESPSETPG-PSPAGPTRDEPAK 656
              GP G EP E  +  P GPR P GP G    +  +  PG P   GP   + A+
Sbjct: 200 GFQGPPG-EPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGAR 253



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 42/150 (28%), Positives = 52/150 (34%), Gaps = 40/150 (26%)

Query: 529 PAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPR-PAGPAGDEPAESPSETPG-PSP 586
           P   + +ESP++       GP GD          GPR P GPAG    +     PG P P
Sbjct: 93  PVCPDGSESPTDQETTGVEGPKGDT---------GPRGPRGPAGPPGRDGIPGQPGLPGP 143

Query: 587 AGPTRDEPAESPSETPGPRPAGPAG-------------DEPAESPSETPGPRPAGPAGDE 633
            GP              P P GP G             DE +      PGP   GP+G  
Sbjct: 144 PGP--------------PGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPM--GPSGPR 187

Query: 634 PAESPSETPGPSPAGPTRDEPAKAGEAAEL 663
               P   PGP        EP + G +  +
Sbjct: 188 GLPGPPGAPGPQGFQGPPGEPGEPGASGPM 217



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 90/336 (26%), Positives = 106/336 (31%), Gaps = 88/336 (26%)

Query: 287  GPQDKLRRFKPSSLPHPLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKG--------G 338
            GP  +     P   P P        E+GSPG  D  A   G T GP+   G        G
Sbjct: 914  GPAGRPGEVGPPGPPGP------AGEKGSPG-ADGPAGAPG-TPGPQGIAGQRGVVGLPG 965

Query: 339  GRVDEG----PQPRSVEPQDAGPLERSQGDEAGGHGEDRPE-PLSPKESKKRKLELSRRE 393
             R + G    P P S EP   GP        +G  GE  P  P+ P        E  R  
Sbjct: 966  QRGERGFPGLPGP-SGEPGKQGP--------SGASGERGPPGPMGPPGLAGPPGESGREG 1016

Query: 394  QPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGARVAD 453
             P  E  P             +G   ++G       E G   P  A      P     A 
Sbjct: 1017 APGAEGSP-----------GRDGSPGAKGD----RGETGPAGPPGAPGAPGAPGPVGPAG 1061

Query: 454  KVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDT--------E 505
            K   R +    AG +  V   GA+     G   P G P+    E G + D          
Sbjct: 1062 KSGDRGETGP-AGPAGPVGPVGAR-----GPAGPQG-PRGDKGETGEQGDRGIKGHRGFS 1114

Query: 506  GRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPG-------------PRPAGPAGD 552
            G  GP  G PGSP E      +GPAG       +  PG             P P G  GD
Sbjct: 1115 GLQGPP-GPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGD 1173

Query: 553  EPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAG 588
                          AGP G      P   PGP  AG
Sbjct: 1174 --------------AGPVGPPGPPGPPGPPGPPSAG 1195



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 25/80 (31%), Positives = 30/80 (37%), Gaps = 8/80 (10%)

Query: 572 DEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPR-PAGPA 630
           DE    P          P   + +ESP++       GP GD          GPR PAGP 
Sbjct: 76  DETKNCPGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPR------GPRGPAGPP 129

Query: 631 GDEPAESPSETPG-PSPAGP 649
           G +        PG P P GP
Sbjct: 130 GRDGIPGQPGLPGPPGPPGP 149


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 88.2 bits (217), Expect = 2e-17
 Identities = 97/369 (26%), Positives = 130/369 (35%), Gaps = 44/369 (11%)

Query: 319 PDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGEDRPEPLS 378
           P    S  G+  GP     GG   +GP P   +PQ  GP  +      G     +P+   
Sbjct: 47  PQGPPSPPGKPQGPPPQ--GGNQPQGPPPPPGKPQ--GPPPQGGNKPQGPPPPGKPQGPP 102

Query: 379 PKESKKRKLELSRREQP--PTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGGQDP 436
           P+  K R    S R  P  P  P PQ  ++ +       G     G  + G    GG  P
Sbjct: 103 PQGDKSR----SPRSPPGKPQGPPPQGGNQPQ-------GPPPPPGKPQ-GPPPQGGNKP 150

Query: 437 GEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHS 496
            +   P  +P G       + R               GG Q     G P P G P+    
Sbjct: 151 -QGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQP---QGPPPPPGKPQGPPP 206

Query: 497 ENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETP-GPRPAG---PAGD 552
           + G           K   P  P +  GP P G    + A SP   P GP P G   P G 
Sbjct: 207 QGG----------NKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGP 256

Query: 553 EPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETP-GPRPAG--- 608
            P   P +  GP P G    +    P +  GP P G ++   + SP   P GP P G   
Sbjct: 257 PPP--PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQ 314

Query: 609 PAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDAEV 668
           P G  P   P +  GP P G    +    P +  GP P G ++   A++         + 
Sbjct: 315 PQGPPPP--PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQ 372

Query: 669 ESSAKSGKP 677
           E +   G P
Sbjct: 373 EGNNPQGPP 381



 Score = 84.7 bits (208), Expect = 3e-16
 Identities = 94/363 (25%), Positives = 126/363 (34%), Gaps = 54/363 (14%)

Query: 303 PLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKG--------GGRVDEGPQPRSVEPQD 354
           P +G  K +    PG P        ++  P    G        GG   +GP P   +PQ 
Sbjct: 82  PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ- 140

Query: 355 AGPLERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQP--PTEPGPQSASEVEKIAL 412
            GP  +      G     +P+   P+   K +   S R  P  P  P PQ  ++ +    
Sbjct: 141 -GPPPQGGNKPQGPPPPGKPQGPPPQGDNKSR---SSRSPPGKPQGPPPQGGNQPQ---- 192

Query: 413 NLEGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVA 472
                         G     G+  G   Q   +P G     K +      +    SA   
Sbjct: 193 --------------GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSP 238

Query: 473 SGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGD 532
            G  Q     G   P G P       G  +    + G K   P  P +  GP P G +  
Sbjct: 239 PGKPQGPPPQGGNQPQGPPPPP----GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKS 294

Query: 533 EPAESPSETP-GPRPAG---PAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAG 588
             + SP   P GP P G   P G  P   P +  GP P G    +    P +  GP P G
Sbjct: 295 RSSRSPPGKPQGPPPQGGNQPQGPPPP--PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG 352

Query: 589 PTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAG 648
            ++   A SP   PG +P GP    P +  +   GP P  PAG  P + P   P   P G
Sbjct: 353 GSKSRSARSP---PG-KPQGP----PQQEGNNPQGPPP--PAGGNP-QQPQAPPAGQPQG 401

Query: 649 PTR 651
           P R
Sbjct: 402 PPR 404



 Score = 71.2 bits (173), Expect = 3e-12
 Identities = 66/236 (27%), Positives = 83/236 (35%), Gaps = 35/236 (14%)

Query: 462 DEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSET 521
           D    +S ++ +G  Q     G   P G P       G          P +G  G+  + 
Sbjct: 22  DVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGP---------PPQG--GNQPQG 70

Query: 522 PGPSPAGPAGDEP--------AESPSETPGPRPAGPAGDEPAESPSETPGPRPAG---PA 570
           P P P  P G  P           P +  GP P G     P   P +  GP P G   P 
Sbjct: 71  PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQ 130

Query: 571 GDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETP-GPRPAG- 628
           G  P   P +  GP P G  + +    P +  GP P G      + SP   P GP P G 
Sbjct: 131 G--PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGG 188

Query: 629 --PAGDEPAESPSETPGPSPAG---PTRDEPAKAGEAAELQDAEVESSAKS--GKP 677
             P G  P   P +  GP P G   P    P    +    Q      SA+S  GKP
Sbjct: 189 NQPQG--PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKP 242


>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
           sapiens]
          Length = 309

 Score = 84.7 bits (208), Expect = 3e-16
 Identities = 61/185 (32%), Positives = 84/185 (45%), Gaps = 11/185 (5%)

Query: 484 SPAPSGHPKAGHSENGVE-EDTEGRTGPKEGTP---GSPSETPGPSPAGPAGDEP-AESP 538
           +P P G P+    + G + +    R G  EG P   G+ S+ P P P  P G  P   + 
Sbjct: 50  TPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQ 109

Query: 539 SETPGPRPAGPAGDEP-AESPSETPGPRPAGPAGDEP-AESPSETPGPSPAGPTRDEP-A 595
           S+ P PRP  P G  P   + S+ P PRP  P G  P   + S+ P P P  P    P  
Sbjct: 110 SQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQG 169

Query: 596 ESPSETPGPRPAGPAGDEP-AESPSETPGPRPAGPAGDEPAESPSETPGPSP-AGPTRDE 653
            + S+ P P P  P G  P   + S+ P PRP  P G  P +  +++ GP P  G     
Sbjct: 170 GNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEG-PPPQGGNQSQGPPPRPGKPEGP 228

Query: 654 PAKAG 658
           P++ G
Sbjct: 229 PSQGG 233



 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 60/177 (33%), Positives = 78/177 (44%), Gaps = 10/177 (5%)

Query: 488 SGHPKAGHSENGVE-EDTEGRTGPKEGTP---GSPSETPGPSPAGPAGDEP-AESPSETP 542
           SG P+    + G + + T    G  EG P   G+ S+ P P P  P G  P   + S+ P
Sbjct: 33  SGKPEGRRPQGGNQPQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGP 92

Query: 543 GPRPAGPAGDEP-AESPSETPGPRPAGPAGDEP-AESPSETPGPSPAGPTRDEP-AESPS 599
            PRP  P G  P   + S+ P PRP  P G  P   + S+ P P P  P    P   + S
Sbjct: 93  PPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQS 152

Query: 600 ETPGPRPAGPAGDEP-AESPSETPGPRPAGPAGDEP-AESPSETPGPSPAGPTRDEP 654
           + P PRP  P G  P   + S+ P P P  P G  P   + S+ P P P  P    P
Sbjct: 153 QGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPP 209



 Score = 81.3 bits (199), Expect = 3e-15
 Identities = 72/252 (28%), Positives = 95/252 (37%), Gaps = 22/252 (8%)

Query: 427 GTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPA 486
           G +  GG  P     P  +P G       + +               GG Q+      P 
Sbjct: 38  GRRPQGGNQPQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPG 97

Query: 487 -PSGHPKAGHSENGVEEDTEGRTGPKEGTP---GSPSETPGPSPAGPAGDEP-AESPSET 541
            P G P  G +++   +    R G  EG P   G+ S+ P P P  P G  P   + S+ 
Sbjct: 98  KPEGQPPQGGNQS---QGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQG 154

Query: 542 PGPRPAGPAGDEP-AESPSETPGPRPAGPAGDEP-AESPSETPGPSPAGPTRDEP-AESP 598
           P PRP  P G  P   + S+ P P P  P G  P   + S+ P P P  P    P   + 
Sbjct: 155 PPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQ 214

Query: 599 SETPGPRPAGPAG-DEPAESPSETPGPRPAGPAGDEPAES--------PSETPGPSPAG- 648
           S+ P PRP  P G      +  + P P P  P G  P E         P    GP P G 
Sbjct: 215 SQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGG 274

Query: 649 -PTRDEPAKAGE 659
            P +  P  AG+
Sbjct: 275 NPQQPLPPPAGK 286



 Score = 79.0 bits (193), Expect = 1e-14
 Identities = 59/190 (31%), Positives = 80/190 (42%), Gaps = 13/190 (6%)

Query: 474 GGAQTLALAGSPA-PSGHPKAGHSENGVEEDTEGRTGPKEGTP---GSPSETPGPSPAGP 529
           GG Q+      P  P G P  G +++   +    R G  EG P   G+ S+ P P P  P
Sbjct: 106 GGNQSQGPPPRPGKPEGPPPQGGNQS---QGPPPRPGKPEGPPPQGGNQSQGPPPRPGKP 162

Query: 530 AGDEP-AESPSETPGPRPAGPAGDEP-AESPSETPGPRPAGPAGDEPAESPSETPGPSP- 586
            G  P   + S+ P P P  P G  P   + S+ P PRP  P G  P +  +++ GP P 
Sbjct: 163 EGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEG-PPPQGGNQSQGPPPR 221

Query: 587 AGPTRDEPAE--SPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGP 644
            G     P++  +  + P P P  P G  P E       P P  P G  P     + P P
Sbjct: 222 PGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLP 281

Query: 645 SPAGPTRDEP 654
            PAG  +  P
Sbjct: 282 PPAGKPQGPP 291



 Score = 76.6 bits (187), Expect = 7e-14
 Identities = 61/182 (33%), Positives = 80/182 (43%), Gaps = 10/182 (5%)

Query: 479 LALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEP-AES 537
           LAL+ + + +       S + +    EGR  P+ G    P  TP P P  P G  P   +
Sbjct: 11  LALSSAQSLNEDVSQEESPSVISGKPEGRR-PQGGN--QPQRTP-PPPGKPEGRPPQGGN 66

Query: 538 PSETPGPRPAGPAGDEP-AESPSETPGPRPAGPAGDEP-AESPSETPGPSPAGPTRDEP- 594
            S+ P PRP  P G  P   + S+ P PRP  P G  P   + S+ P P P  P    P 
Sbjct: 67  QSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQ 126

Query: 595 AESPSETPGPRPAGPAGDEP-AESPSETPGPRPAGPAGDEP-AESPSETPGPSPAGPTRD 652
             + S+ P PRP  P G  P   + S+ P PRP  P G  P   + S+ P P P  P   
Sbjct: 127 GGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGP 186

Query: 653 EP 654
            P
Sbjct: 187 PP 188



 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 76/297 (25%), Positives = 106/297 (35%), Gaps = 40/297 (13%)

Query: 371 EDRPEPLSPKESKKRKLELSRREQPPTEPG------PQSASEVEKIALNLEGCALSQGSL 424
           E+ P  +S K   +R    ++ ++ P  PG      PQ  ++ +       G     G  
Sbjct: 26  EESPSVISGKPEGRRPQGGNQPQRTPPPPGKPEGRPPQGGNQSQ-------GPPPRPGKP 78

Query: 425 RTGTQEVGGQDPGEAVQPCRQ----PLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLA 480
                + G Q  G   +P +     P G   +     R    EG         GG Q+  
Sbjct: 79  EGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQ-----GGNQSQG 133

Query: 481 LAGSPA-PSGHPKAGHSENGVEEDTEGRTGPKEGTP---GSPSETPGPSPAGPAGDEP-A 535
               P  P G P  G +++   +    R G  EG P   G+ S+ P P P  P G  P  
Sbjct: 134 PPPRPGKPEGPPPQGGNQS---QGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQG 190

Query: 536 ESPSETPGPRPAGPAGDEP-AESPSETPGPRPAGPAGDE---------PAESPSETPGPS 585
            + S+ P PRP  P G  P   + S+ P PRP  P G           P   P +  GP 
Sbjct: 191 GNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPP 250

Query: 586 PAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETP 642
           P    + +    P    GP P G    +P   P+  P   P  P G  P   P   P
Sbjct: 251 PQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQGGRPHRPPQGQP 307



 Score = 66.6 bits (161), Expect = 7e-11
 Identities = 80/333 (24%), Positives = 109/333 (32%), Gaps = 49/333 (14%)

Query: 289 QDKLRRFKPSSLPHPLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPR 348
           +D  +   PS +    EG R          P      +GR   P+    GG   +GP PR
Sbjct: 21  EDVSQEESPSVISGKPEGRRPQGGNQPQRTPPPPGKPEGRP--PQ----GGNQSQGPPPR 74

Query: 349 SVEPQDAGPLERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVE 408
             +P+   P         GG+    P P   K   +     ++ + PP  PG        
Sbjct: 75  PGKPEGPPP--------QGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKP------ 120

Query: 409 KIALNLEGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDS 468
                       +G    G  +  G  P         P G   +     R    EG    
Sbjct: 121 ------------EGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQ 168

Query: 469 AAVASGGAQTLALAGSPA-PSGHPKAGHSENGVEEDTEGRTGPKEGTP---GSPSETPGP 524
                GG Q+      P  P G P  G +++   +    R G  EG P   G+ S+ P P
Sbjct: 169 -----GGNQSQGPPPHPGKPEGPPPQGGNQS---QGPPPRPGKPEGPPPQGGNQSQGPPP 220

Query: 525 SPAGPAG-DEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG 583
            P  P G      +  + P P P  P G  P E       P P  P G  P     + P 
Sbjct: 221 RPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPL 280

Query: 584 PSPAGPTRDEPAESPSETPGPRPAGPAGDEPAE 616
           P PAG    +P   P    G RP  P   +P +
Sbjct: 281 PPPAG----KPQGPPPPPQGGRPHRPPQGQPPQ 309



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 33/110 (30%), Positives = 46/110 (41%), Gaps = 5/110 (4%)

Query: 557 SPSETPGPRPAGPAGDEP--AESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEP 614
           S  E+P      P G  P     P  TP P      R     + S+ P PRP  P G  P
Sbjct: 24  SQEESPSVISGKPEGRRPQGGNQPQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPP 83

Query: 615 -AESPSETPGPRPAGPAGDEPAESPSETPGPSP-AGPTRDEPAKAGEAAE 662
              + S+ P PRP  P G +P +  +++ GP P  G     P + G  ++
Sbjct: 84  QGGNQSQGPPPRPGKPEG-QPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQ 132


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
            sapiens]
          Length = 1650

 Score = 82.4 bits (202), Expect = 1e-15
 Identities = 114/436 (26%), Positives = 151/436 (34%), Gaps = 65/436 (14%)

Query: 297  PSSLPHPLEGSRKVEEEGSPGDPDH--EASTQGRTCGPEHSKG-----GGRVDEGPQPRS 349
            P+  P P        ++G PG P    E   QG+T GP    G     G   + GP    
Sbjct: 798  PNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKT-GPPGPPGVVGPQGAAGETGPMGER 856

Query: 350  VEPQDAGP-----------LERSQGDEA--GGHGEDRPEPLSPKESKKRKLE------LS 390
              P   GP            E ++GD    G  G+D P  L     ++          L 
Sbjct: 857  GHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLK 916

Query: 391  RREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGAR 450
              E P   PGP + S  E+ A    G     G  R G Q   G    + V   + P+G  
Sbjct: 917  GNEGPSGPPGP-AGSPGERGAAGSGGPIGPPG--RPGPQGPPGAAGEKGVPGEKGPIGPT 973

Query: 451  VADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGP 510
              D V+    +   AG        G +     G P   G  K    E+G      G  GP
Sbjct: 974  GRDGVQGPVGLPGPAGPPGVAGEDGDK--GEVGDPGQKG-TKGNKGEHG-PPGPPGPIGP 1029

Query: 511  KEGTPGSPSETPGPSPAGPAGDEPAESPSETPG-------------PRPAGPAGDEPAES 557
              G PG+      P   GP G   A+    T G             P P+G  G+     
Sbjct: 1030 V-GQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVG 1088

Query: 558  PSETPGPR-PAGPAGDEPAESPSETPGP-SPAGPTRDEPAESPSETPG----PRPAGPAG 611
            P   PGP  P GPAG   A+ P   PG     GP  ++     S +PG    P   GP G
Sbjct: 1089 PMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRG 1148

Query: 612  DEPAESPSETPG----PRPAGPAGDE-------PAESPSETPGPSPAGPTRDEPAKAGEA 660
            +   +  S  PG    P P GP GD+       P   P +   P   GP   + AK    
Sbjct: 1149 ERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRG 1208

Query: 661  AELQDAEVESSAKSGK 676
             + +  +  S   +G+
Sbjct: 1209 EDGEPGQPGSPGPTGE 1224



 Score = 82.4 bits (202), Expect = 1e-15
 Identities = 119/427 (27%), Positives = 146/427 (34%), Gaps = 79/427 (18%)

Query: 312  EEGSPGDPDHEASTQGR--TCGPEHSKGGGRVDEGPQPRSVEPQDAG----PLERSQGDE 365
            E G PG P      QG   T G E +KG    D GP     +   AG    P ER     
Sbjct: 855  ERGHPGPPGPPGE-QGLPGTAGKEGTKG----DPGPPGAPGKDGPAGLRGFPGERGLPGT 909

Query: 366  AGGHG----EDRPEPLSPKESKKRKLELSRREQ--PPTEPGPQ----SASEV----EKIA 411
            AGG G    E    P  P  S   +          PP  PGPQ    +A E     EK  
Sbjct: 910  AGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGP 969

Query: 412  LNLEGCALSQGSLR----TGTQEVGGQD--PGEAVQPCRQPLGARVADKVRKRRKVDEGA 465
            +   G    QG +      G   V G+D   GE   P           K  K  K + G 
Sbjct: 970  IGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDP---------GQKGTKGNKGEHGP 1020

Query: 466  GDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPK-----EGTPG---- 516
                       Q  A      P      GH     +E T G  GP      +G PG    
Sbjct: 1021 PGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGE 1080

Query: 517  -------SPSETPGP-SPAGPAGDEPAESPSETPGP-RPAGPAGDEPAESPSETPG---- 563
                    P   PGP  P GPAG   A+ P   PG     GP G++     S +PG    
Sbjct: 1081 KGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGE 1140

Query: 564  PRPAGPAGDEPAESPSETPG----PSPAGPTRDE-------PAESPSETPGPRPAGPAGD 612
            P   GP G+   +  S  PG    P P GPT D+       P   P +   P   GP G 
Sbjct: 1141 PGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQ 1200

Query: 613  EPAESPSETPG----PRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDAEV 668
            + A+      G    P   GP G+     P    G  PAG    E  + G+ A+     +
Sbjct: 1201 DGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRG--PAGSPGSEGRQGGKGAKGDPGAI 1258

Query: 669  ESSAKSG 675
             +  K+G
Sbjct: 1259 GAPGKTG 1265



 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 95/324 (29%), Positives = 117/324 (36%), Gaps = 55/324 (16%)

Query: 359 ERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSA-SEVEKIAL-NLEG 416
           +R +    G  GED PE   PK           R  P  +PGP     E  K+ +  L G
Sbjct: 669 DRGEVGVPGSRGEDGPE--GPKG----------RTGPTGDPGPPGLMGEKGKLGVPGLPG 716

Query: 417 CALSQGSLRT----GTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVA 472
               QG   +    G     G+     +     P G R     R +R      G   A  
Sbjct: 717 YPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQR------GPRGATG 770

Query: 473 SGGAQTLALAGSPAPSGHPKAGHSENGVE--EDTEGRTGPKEGTPGSPSETPGPSPAGPA 530
             GA+    +G   P G P     E G+   +   G  GPK G PG P +   P   G  
Sbjct: 771 KSGAK--GTSGGDGPHGPP----GERGLPGPQGPNGFPGPK-GPPGPPGKDGLPGHPGQR 823

Query: 531 GDEPAESPSETPGPRPA-GPAGDEPAESPSETPG-PRPAGPAGDEPA------ESPSETP 582
           G+   +  +  PGP    GP G      P    G P P GP G++        E     P
Sbjct: 824 GEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDP 883

Query: 583 GPSPAGPTRDEPAES---PSETPGPRPAGPAGDEPAESPSETPGPRPA----GPAGDEPA 635
           GP P  P +D PA     P E   P  AG  G +  E PS  PGP  +    G AG    
Sbjct: 884 GP-PGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGP 942

Query: 636 ESPSETPGPSPAGPTRDEPAKAGE 659
             P   PGP   GP    P  AGE
Sbjct: 943 IGPPGRPGPQ--GP----PGAAGE 960



 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 93/363 (25%), Positives = 119/363 (32%), Gaps = 75/363 (20%)

Query: 314  GSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPL-ERSQGDEAGGHG-E 371
            G PG P           GP    G    D GPQ       + GP  E+ +  E+G  G +
Sbjct: 1091 GPPGPP-----------GPRGPAGPNGAD-GPQGPPGGVGNLGPPGEKGEPGESGSPGIQ 1138

Query: 372  DRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEV 431
              P    P+  +  K E  +    P EPGP             +G     G         
Sbjct: 1139 GEPGVKGPRGERGEKGESGQ----PGEPGPPGP----------KGPTGDDGPKGNPGPVG 1184

Query: 432  GGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHP 491
               DPG   +      G R  D  +  R  D   G   +    G       G P P G  
Sbjct: 1185 FPGDPGPPGEG-----GPRGQDGAKGDRGEDGEPGQPGSPGPTGEN-----GPPGPLG-- 1232

Query: 492  KAGHSENGVEEDTEGRTGPK--EGTPGSPSETPGPSPAGPAGDEPAESPSETPG------ 543
            K G + +   E  +G  G K   G  G+P +T    PAGPAG    +     PG      
Sbjct: 1233 KRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQG 1292

Query: 544  -PRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG-------PSPAGPTRDEPA 595
             P   G AG      P   PG R     GD  A+     PG       P   G   D   
Sbjct: 1293 RPGATGQAGPPGPVGPPGLPGLR-----GDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGL 1347

Query: 596  ESPSETPGPR----------PAGPAGDEPAESPSETPGPR----PAGPAGDEPAESPSET 641
              P  +PG +          P GP G      P+   G +    P GP G++  + P   
Sbjct: 1348 PGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGH 1407

Query: 642  PGP 644
            PGP
Sbjct: 1408 PGP 1410



 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 97/391 (24%), Positives = 131/391 (33%), Gaps = 73/391 (18%)

Query: 306 GSRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQ---PRSVEPQDAGPLERSQ 362
           G+R ++EE   GD    A   G     E  +      EG Q   P++ +P  A    + Q
Sbjct: 192 GARILDEEVFEGDVQELAIVPGVQAAYESCEQKELECEGGQRERPQNQQPHRAQRSPQQQ 251

Query: 363 GDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEP---------GPQSASEVEKIALN 413
                      P+   P   ++ ++ L     PP E          G +    V +  + 
Sbjct: 252 PSRLHRPQNQEPQSQDPTPGEEEEI-LESSLLPPLEEAAHGPRGLKGEKGEPAVLEPGML 310

Query: 414 LEGCALSQGSLRT-GTQEVGGQ-----DPGEAVQPCRQPLGAR------VADKVRKRRKV 461
           +EG    +G     G   + G      DPGE   P R  L             +    + 
Sbjct: 311 VEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRF 370

Query: 462 DEGAGDSA-AVASGGAQT--------LALAGSPAPSGHPKAGHSENGVEEDTEGRTGP-- 510
             G GD    VA+  AQ         LAL G P P G+               GR GP  
Sbjct: 371 GSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYT--------------GRPGPLG 416

Query: 511 KEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG------- 563
           + G+PG   E+    P GP G +    P    G R  G AG + A      PG       
Sbjct: 417 QPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRR--GRAGADGARGMPGDPGVKGDRGF 474

Query: 564 ------PRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAES 617
                 P   G  GD  A+     PG    G   D+    P   PG   +GP G    + 
Sbjct: 475 DGLPGLPGEKGHRGDTGAQGLPGPPGED--GERGDDGEIGPRGLPG--ESGPRGLLGPKG 530

Query: 618 PSETPGPRPA----GPAGDEPAESPSETPGP 644
           P   PGP       GP G + +  P   PGP
Sbjct: 531 PPGIPGPPGVRGMDGPQGPKGSLGPQGEPGP 561



 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 53/184 (28%), Positives = 65/184 (35%), Gaps = 16/184 (8%)

Query: 473 SGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSE--TPG----PSP 526
           SG    L   G P   G P     +    +  +G  GP +G PG P +  TPG    P P
Sbjct: 520 SGPRGLLGPKGPPGIPGPPGVRGMDG--PQGPKGSLGP-QGEPGPPGQQGTPGTQGLPGP 576

Query: 527 AGPAGDEPAESPSETPG----PRPAGPAGDEPAESPSETPGPR-PAGPAGDEPAESPSET 581
            G  G    + P   PG    P   GP G    E P  T G + P+GP G      P   
Sbjct: 577 QGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGV 636

Query: 582 PGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPR-PAGPAGDEPAESPSE 640
            G       +    E   E   P   G  G +        PG R   GP G +    P+ 
Sbjct: 637 KGVDGIRGLKGHKGEK-GEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTG 695

Query: 641 TPGP 644
            PGP
Sbjct: 696 DPGP 699



 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 110/436 (25%), Positives = 128/436 (29%), Gaps = 133/436 (30%)

Query: 314 GSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGEDR 373
           G PGDP  +             + G R D G Q     P + G        E G  GE  
Sbjct: 461 GMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDG--------ERGDDGEIG 512

Query: 374 PEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGG 433
           P  L P ES  R L     + PP  PGP            ++G    +GSL  G Q   G
Sbjct: 513 PRGL-PGESGPRGL--LGPKGPPGIPGPPGVR-------GMDGPQGPKGSL--GPQGEPG 560

Query: 434 QDPGEAVQPCRQPLGARVADKVRKRRKVDEGA-GDSAAVASGGAQTL-ALAGSPAPSGHP 491
             PG+   P  Q L               +GA G        G   L  + GS  P GHP
Sbjct: 561 P-PGQQGTPGTQGLPG------------PQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHP 607

Query: 492 KAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPA---- 547
                              KEG PG+        P GP G          PGPR      
Sbjct: 608 G------------------KEGPPGTKGNQGPSGPQGPLG---------YPGPRGVKGVD 640

Query: 548 ---------------------GPAGDEPAESPSETPGPR-PAGPAGDEPAESPSETPGPS 585
                                G  G +        PG R   GP G +    P+  PGP 
Sbjct: 641 GIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPP 700

Query: 586 --------------PAGPTRDEPAES--------PSETPGPR----PAGPAGDEPAESPS 619
                         P  P R  P  S         S   G R     +GP G+     P 
Sbjct: 701 GLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPR 760

Query: 620 ETPGPR----------------PAGPAGDEPAESPSETPG-PSPAGPTRDEPAKAGEAAE 662
              GPR                P GP G+     P    G P P GP    P K G    
Sbjct: 761 GQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPP-GPPGKDGLPGH 819

Query: 663 L-QDAEVESSAKSGKP 677
             Q  EV    K+G P
Sbjct: 820 PGQRGEVGFQGKTGPP 835



 Score = 38.1 bits (87), Expect = 0.027
 Identities = 34/119 (28%), Positives = 41/119 (34%), Gaps = 3/119 (2%)

Query: 540 ETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPS 599
           E P  +    A   P + PS    P+   P   +P     E    S   P  +E A  P 
Sbjct: 234 ERPQNQQPHRAQRSPQQQPSRLHRPQNQEPQSQDPTPGEEEEILESSLLPPLEEAAHGPR 293

Query: 600 ETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAG 658
              G +   PA  EP       PGP   GPAG          PGP      R  P +AG
Sbjct: 294 GLKGEK-GEPAVLEPGMLVEGPPGPE--GPAGLIGPPGIQGNPGPVGDPGERGPPGRAG 349


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
            sapiens]
          Length = 1629

 Score = 82.4 bits (202), Expect = 1e-15
 Identities = 114/436 (26%), Positives = 151/436 (34%), Gaps = 65/436 (14%)

Query: 297  PSSLPHPLEGSRKVEEEGSPGDPDH--EASTQGRTCGPEHSKG-----GGRVDEGPQPRS 349
            P+  P P        ++G PG P    E   QG+T GP    G     G   + GP    
Sbjct: 777  PNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKT-GPPGPPGVVGPQGAAGETGPMGER 835

Query: 350  VEPQDAGP-----------LERSQGDEA--GGHGEDRPEPLSPKESKKRKLE------LS 390
              P   GP            E ++GD    G  G+D P  L     ++          L 
Sbjct: 836  GHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLK 895

Query: 391  RREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGAR 450
              E P   PGP + S  E+ A    G     G  R G Q   G    + V   + P+G  
Sbjct: 896  GNEGPSGPPGP-AGSPGERGAAGSGGPIGPPG--RPGPQGPPGAAGEKGVPGEKGPIGPT 952

Query: 451  VADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGP 510
              D V+    +   AG        G +     G P   G  K    E+G      G  GP
Sbjct: 953  GRDGVQGPVGLPGPAGPPGVAGEDGDK--GEVGDPGQKG-TKGNKGEHG-PPGPPGPIGP 1008

Query: 511  KEGTPGSPSETPGPSPAGPAGDEPAESPSETPG-------------PRPAGPAGDEPAES 557
              G PG+      P   GP G   A+    T G             P P+G  G+     
Sbjct: 1009 V-GQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVG 1067

Query: 558  PSETPGPR-PAGPAGDEPAESPSETPGP-SPAGPTRDEPAESPSETPG----PRPAGPAG 611
            P   PGP  P GPAG   A+ P   PG     GP  ++     S +PG    P   GP G
Sbjct: 1068 PMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRG 1127

Query: 612  DEPAESPSETPG----PRPAGPAGDE-------PAESPSETPGPSPAGPTRDEPAKAGEA 660
            +   +  S  PG    P P GP GD+       P   P +   P   GP   + AK    
Sbjct: 1128 ERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRG 1187

Query: 661  AELQDAEVESSAKSGK 676
             + +  +  S   +G+
Sbjct: 1188 EDGEPGQPGSPGPTGE 1203



 Score = 82.4 bits (202), Expect = 1e-15
 Identities = 119/427 (27%), Positives = 146/427 (34%), Gaps = 79/427 (18%)

Query: 312  EEGSPGDPDHEASTQGR--TCGPEHSKGGGRVDEGPQPRSVEPQDAG----PLERSQGDE 365
            E G PG P      QG   T G E +KG    D GP     +   AG    P ER     
Sbjct: 834  ERGHPGPPGPPGE-QGLPGTAGKEGTKG----DPGPPGAPGKDGPAGLRGFPGERGLPGT 888

Query: 366  AGGHG----EDRPEPLSPKESKKRKLELSRREQ--PPTEPGPQ----SASEV----EKIA 411
            AGG G    E    P  P  S   +          PP  PGPQ    +A E     EK  
Sbjct: 889  AGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGP 948

Query: 412  LNLEGCALSQGSLR----TGTQEVGGQD--PGEAVQPCRQPLGARVADKVRKRRKVDEGA 465
            +   G    QG +      G   V G+D   GE   P           K  K  K + G 
Sbjct: 949  IGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDP---------GQKGTKGNKGEHGP 999

Query: 466  GDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPK-----EGTPG---- 516
                       Q  A      P      GH     +E T G  GP      +G PG    
Sbjct: 1000 PGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGE 1059

Query: 517  -------SPSETPGP-SPAGPAGDEPAESPSETPGP-RPAGPAGDEPAESPSETPG---- 563
                    P   PGP  P GPAG   A+ P   PG     GP G++     S +PG    
Sbjct: 1060 KGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGE 1119

Query: 564  PRPAGPAGDEPAESPSETPG----PSPAGPTRDE-------PAESPSETPGPRPAGPAGD 612
            P   GP G+   +  S  PG    P P GPT D+       P   P +   P   GP G 
Sbjct: 1120 PGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQ 1179

Query: 613  EPAESPSETPG----PRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDAEV 668
            + A+      G    P   GP G+     P    G  PAG    E  + G+ A+     +
Sbjct: 1180 DGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRG--PAGSPGSEGRQGGKGAKGDPGAI 1237

Query: 669  ESSAKSG 675
             +  K+G
Sbjct: 1238 GAPGKTG 1244



 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 95/324 (29%), Positives = 117/324 (36%), Gaps = 55/324 (16%)

Query: 359 ERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSA-SEVEKIAL-NLEG 416
           +R +    G  GED PE   PK           R  P  +PGP     E  K+ +  L G
Sbjct: 648 DRGEVGVPGSRGEDGPE--GPKG----------RTGPTGDPGPPGLMGEKGKLGVPGLPG 695

Query: 417 CALSQGSLRT----GTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVA 472
               QG   +    G     G+     +     P G R     R +R      G   A  
Sbjct: 696 YPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQR------GPRGATG 749

Query: 473 SGGAQTLALAGSPAPSGHPKAGHSENGVE--EDTEGRTGPKEGTPGSPSETPGPSPAGPA 530
             GA+    +G   P G P     E G+   +   G  GPK G PG P +   P   G  
Sbjct: 750 KSGAK--GTSGGDGPHGPP----GERGLPGPQGPNGFPGPK-GPPGPPGKDGLPGHPGQR 802

Query: 531 GDEPAESPSETPGPRPA-GPAGDEPAESPSETPG-PRPAGPAGDEPA------ESPSETP 582
           G+   +  +  PGP    GP G      P    G P P GP G++        E     P
Sbjct: 803 GEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDP 862

Query: 583 GPSPAGPTRDEPAES---PSETPGPRPAGPAGDEPAESPSETPGPRPA----GPAGDEPA 635
           GP P  P +D PA     P E   P  AG  G +  E PS  PGP  +    G AG    
Sbjct: 863 GP-PGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGP 921

Query: 636 ESPSETPGPSPAGPTRDEPAKAGE 659
             P   PGP   GP    P  AGE
Sbjct: 922 IGPPGRPGPQ--GP----PGAAGE 939



 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 93/363 (25%), Positives = 119/363 (32%), Gaps = 75/363 (20%)

Query: 314  GSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPL-ERSQGDEAGGHG-E 371
            G PG P           GP    G    D GPQ       + GP  E+ +  E+G  G +
Sbjct: 1070 GPPGPP-----------GPRGPAGPNGAD-GPQGPPGGVGNLGPPGEKGEPGESGSPGIQ 1117

Query: 372  DRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEV 431
              P    P+  +  K E  +    P EPGP             +G     G         
Sbjct: 1118 GEPGVKGPRGERGEKGESGQ----PGEPGPPGP----------KGPTGDDGPKGNPGPVG 1163

Query: 432  GGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHP 491
               DPG   +      G R  D  +  R  D   G   +    G       G P P G  
Sbjct: 1164 FPGDPGPPGEG-----GPRGQDGAKGDRGEDGEPGQPGSPGPTGEN-----GPPGPLG-- 1211

Query: 492  KAGHSENGVEEDTEGRTGPK--EGTPGSPSETPGPSPAGPAGDEPAESPSETPG------ 543
            K G + +   E  +G  G K   G  G+P +T    PAGPAG    +     PG      
Sbjct: 1212 KRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQG 1271

Query: 544  -PRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG-------PSPAGPTRDEPA 595
             P   G AG      P   PG R     GD  A+     PG       P   G   D   
Sbjct: 1272 RPGATGQAGPPGPVGPPGLPGLR-----GDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGL 1326

Query: 596  ESPSETPGPR----------PAGPAGDEPAESPSETPGPR----PAGPAGDEPAESPSET 641
              P  +PG +          P GP G      P+   G +    P GP G++  + P   
Sbjct: 1327 PGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGH 1386

Query: 642  PGP 644
            PGP
Sbjct: 1387 PGP 1389



 Score = 60.5 bits (145), Expect = 5e-09
 Identities = 96/384 (25%), Positives = 128/384 (33%), Gaps = 80/384 (20%)

Query: 306 GSRKVEEEGSPGDPDHEASTQG-----RTCGPEHSKGGGRVDEGPQPRSVEPQDAGP--- 357
           G+R ++EE   GD    A   G      +C  +  +  G   E PQ +        P   
Sbjct: 192 GARILDEEVFEGDVQELAIVPGVQAAYESCEQKELECEGGQRERPQNQQPHRAQRSPQQQ 251

Query: 358 ---LERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNL 414
              L R Q  E        P  L  ++ +   LE     + P  PGP+  + +       
Sbjct: 252 PSRLHRPQNQEPQSQAAHGPRGLKGEKGEPAVLEPGMLVEGP--PGPEGPAGL------- 302

Query: 415 EGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGAR------VADKVRKRRKVDEGAGDS 468
               +    ++     VG  DPGE   P R  L             +    +   G GD 
Sbjct: 303 ----IGPPGIQGNPGPVG--DPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDK 356

Query: 469 A-AVASGGAQT--------LALAGSPAPSGHPKAGHSENGVEEDTEGRTGP--KEGTPGS 517
              VA+  AQ         LAL G P P G+               GR GP  + G+PG 
Sbjct: 357 GPVVAAQEAQAQAILQQARLALRGPPGPMGYT--------------GRPGPLGQPGSPGL 402

Query: 518 PSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG-------------P 564
             E+    P GP G +    P    G R  G AG + A      PG             P
Sbjct: 403 KGESGDLGPQGPRGPQGLTGPPGKAGRR--GRAGADGARGMPGDPGVKGDRGFDGLPGLP 460

Query: 565 RPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGP 624
              G  GD  A+     PG    G   D+    P   PG   +GP G    + P   PGP
Sbjct: 461 GEKGHRGDTGAQGLPGPPGED--GERGDDGEIGPRGLPG--ESGPRGLLGPKGPPGIPGP 516

Query: 625 RPA----GPAGDEPAESPSETPGP 644
                  GP G + +  P   PGP
Sbjct: 517 PGVRGMDGPQGPKGSLGPQGEPGP 540



 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 53/184 (28%), Positives = 65/184 (35%), Gaps = 16/184 (8%)

Query: 473 SGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSE--TPG----PSP 526
           SG    L   G P   G P     +    +  +G  GP +G PG P +  TPG    P P
Sbjct: 499 SGPRGLLGPKGPPGIPGPPGVRGMDG--PQGPKGSLGP-QGEPGPPGQQGTPGTQGLPGP 555

Query: 527 AGPAGDEPAESPSETPG----PRPAGPAGDEPAESPSETPGPR-PAGPAGDEPAESPSET 581
            G  G    + P   PG    P   GP G    E P  T G + P+GP G      P   
Sbjct: 556 QGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGV 615

Query: 582 PGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPR-PAGPAGDEPAESPSE 640
            G       +    E   E   P   G  G +        PG R   GP G +    P+ 
Sbjct: 616 KGVDGIRGLKGHKGEK-GEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTG 674

Query: 641 TPGP 644
            PGP
Sbjct: 675 DPGP 678



 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 110/436 (25%), Positives = 128/436 (29%), Gaps = 133/436 (30%)

Query: 314 GSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGEDR 373
           G PGDP  +             + G R D G Q     P + G        E G  GE  
Sbjct: 440 GMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDG--------ERGDDGEIG 491

Query: 374 PEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGG 433
           P  L P ES  R L     + PP  PGP            ++G    +GSL  G Q   G
Sbjct: 492 PRGL-PGESGPRGL--LGPKGPPGIPGPPGVR-------GMDGPQGPKGSL--GPQGEPG 539

Query: 434 QDPGEAVQPCRQPLGARVADKVRKRRKVDEGA-GDSAAVASGGAQTL-ALAGSPAPSGHP 491
             PG+   P  Q L               +GA G        G   L  + GS  P GHP
Sbjct: 540 P-PGQQGTPGTQGLPG------------PQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHP 586

Query: 492 KAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPA---- 547
                              KEG PG+        P GP G          PGPR      
Sbjct: 587 G------------------KEGPPGTKGNQGPSGPQGPLG---------YPGPRGVKGVD 619

Query: 548 ---------------------GPAGDEPAESPSETPGPR-PAGPAGDEPAESPSETPGPS 585
                                G  G +        PG R   GP G +    P+  PGP 
Sbjct: 620 GIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPP 679

Query: 586 --------------PAGPTRDEPAES--------PSETPGPR----PAGPAGDEPAESPS 619
                         P  P R  P  S         S   G R     +GP G+     P 
Sbjct: 680 GLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPR 739

Query: 620 ETPGPR----------------PAGPAGDEPAESPSETPG-PSPAGPTRDEPAKAGEAAE 662
              GPR                P GP G+     P    G P P GP    P K G    
Sbjct: 740 GQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPP-GPPGKDGLPGH 798

Query: 663 L-QDAEVESSAKSGKP 677
             Q  EV    K+G P
Sbjct: 799 PGQRGEVGFQGKTGPP 814


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score = 82.4 bits (202), Expect = 1e-15
 Identities = 114/436 (26%), Positives = 151/436 (34%), Gaps = 65/436 (14%)

Query: 297  PSSLPHPLEGSRKVEEEGSPGDPDH--EASTQGRTCGPEHSKG-----GGRVDEGPQPRS 349
            P+  P P        ++G PG P    E   QG+T GP    G     G   + GP    
Sbjct: 884  PNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKT-GPPGPPGVVGPQGAAGETGPMGER 942

Query: 350  VEPQDAGP-----------LERSQGDEA--GGHGEDRPEPLSPKESKKRKLE------LS 390
              P   GP            E ++GD    G  G+D P  L     ++          L 
Sbjct: 943  GHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLK 1002

Query: 391  RREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGAR 450
              E P   PGP + S  E+ A    G     G  R G Q   G    + V   + P+G  
Sbjct: 1003 GNEGPSGPPGP-AGSPGERGAAGSGGPIGPPG--RPGPQGPPGAAGEKGVPGEKGPIGPT 1059

Query: 451  VADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGP 510
              D V+    +   AG        G +     G P   G  K    E+G      G  GP
Sbjct: 1060 GRDGVQGPVGLPGPAGPPGVAGEDGDK--GEVGDPGQKG-TKGNKGEHG-PPGPPGPIGP 1115

Query: 511  KEGTPGSPSETPGPSPAGPAGDEPAESPSETPG-------------PRPAGPAGDEPAES 557
              G PG+      P   GP G   A+    T G             P P+G  G+     
Sbjct: 1116 V-GQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVG 1174

Query: 558  PSETPGPR-PAGPAGDEPAESPSETPGP-SPAGPTRDEPAESPSETPG----PRPAGPAG 611
            P   PGP  P GPAG   A+ P   PG     GP  ++     S +PG    P   GP G
Sbjct: 1175 PMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRG 1234

Query: 612  DEPAESPSETPG----PRPAGPAGDE-------PAESPSETPGPSPAGPTRDEPAKAGEA 660
            +   +  S  PG    P P GP GD+       P   P +   P   GP   + AK    
Sbjct: 1235 ERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRG 1294

Query: 661  AELQDAEVESSAKSGK 676
             + +  +  S   +G+
Sbjct: 1295 EDGEPGQPGSPGPTGE 1310



 Score = 82.4 bits (202), Expect = 1e-15
 Identities = 119/427 (27%), Positives = 146/427 (34%), Gaps = 79/427 (18%)

Query: 312  EEGSPGDPDHEASTQGR--TCGPEHSKGGGRVDEGPQPRSVEPQDAG----PLERSQGDE 365
            E G PG P      QG   T G E +KG    D GP     +   AG    P ER     
Sbjct: 941  ERGHPGPPGPPGE-QGLPGTAGKEGTKG----DPGPPGAPGKDGPAGLRGFPGERGLPGT 995

Query: 366  AGGHG----EDRPEPLSPKESKKRKLELSRREQ--PPTEPGPQ----SASEV----EKIA 411
            AGG G    E    P  P  S   +          PP  PGPQ    +A E     EK  
Sbjct: 996  AGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGP 1055

Query: 412  LNLEGCALSQGSLR----TGTQEVGGQD--PGEAVQPCRQPLGARVADKVRKRRKVDEGA 465
            +   G    QG +      G   V G+D   GE   P           K  K  K + G 
Sbjct: 1056 IGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDP---------GQKGTKGNKGEHGP 1106

Query: 466  GDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPK-----EGTPG---- 516
                       Q  A      P      GH     +E T G  GP      +G PG    
Sbjct: 1107 PGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGE 1166

Query: 517  -------SPSETPGP-SPAGPAGDEPAESPSETPGP-RPAGPAGDEPAESPSETPG---- 563
                    P   PGP  P GPAG   A+ P   PG     GP G++     S +PG    
Sbjct: 1167 KGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGE 1226

Query: 564  PRPAGPAGDEPAESPSETPG----PSPAGPTRDE-------PAESPSETPGPRPAGPAGD 612
            P   GP G+   +  S  PG    P P GPT D+       P   P +   P   GP G 
Sbjct: 1227 PGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQ 1286

Query: 613  EPAESPSETPG----PRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDAEV 668
            + A+      G    P   GP G+     P    G  PAG    E  + G+ A+     +
Sbjct: 1287 DGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRG--PAGSPGSEGRQGGKGAKGDPGAI 1344

Query: 669  ESSAKSG 675
             +  K+G
Sbjct: 1345 GAPGKTG 1351



 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 95/324 (29%), Positives = 117/324 (36%), Gaps = 55/324 (16%)

Query: 359  ERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSA-SEVEKIAL-NLEG 416
            +R +    G  GED PE   PK           R  P  +PGP     E  K+ +  L G
Sbjct: 755  DRGEVGVPGSRGEDGPE--GPKG----------RTGPTGDPGPPGLMGEKGKLGVPGLPG 802

Query: 417  CALSQGSLRT----GTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVA 472
                QG   +    G     G+     +     P G R     R +R      G   A  
Sbjct: 803  YPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQR------GPRGATG 856

Query: 473  SGGAQTLALAGSPAPSGHPKAGHSENGVE--EDTEGRTGPKEGTPGSPSETPGPSPAGPA 530
              GA+    +G   P G P     E G+   +   G  GPK G PG P +   P   G  
Sbjct: 857  KSGAK--GTSGGDGPHGPP----GERGLPGPQGPNGFPGPK-GPPGPPGKDGLPGHPGQR 909

Query: 531  GDEPAESPSETPGPRPA-GPAGDEPAESPSETPG-PRPAGPAGDEPA------ESPSETP 582
            G+   +  +  PGP    GP G      P    G P P GP G++        E     P
Sbjct: 910  GEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDP 969

Query: 583  GPSPAGPTRDEPAES---PSETPGPRPAGPAGDEPAESPSETPGPRPA----GPAGDEPA 635
            GP P  P +D PA     P E   P  AG  G +  E PS  PGP  +    G AG    
Sbjct: 970  GP-PGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGP 1028

Query: 636  ESPSETPGPSPAGPTRDEPAKAGE 659
              P   PGP   GP    P  AGE
Sbjct: 1029 IGPPGRPGPQ--GP----PGAAGE 1046



 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 93/363 (25%), Positives = 119/363 (32%), Gaps = 75/363 (20%)

Query: 314  GSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPL-ERSQGDEAGGHG-E 371
            G PG P           GP    G    D GPQ       + GP  E+ +  E+G  G +
Sbjct: 1177 GPPGPP-----------GPRGPAGPNGAD-GPQGPPGGVGNLGPPGEKGEPGESGSPGIQ 1224

Query: 372  DRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEV 431
              P    P+  +  K E  +    P EPGP             +G     G         
Sbjct: 1225 GEPGVKGPRGERGEKGESGQ----PGEPGPPGP----------KGPTGDDGPKGNPGPVG 1270

Query: 432  GGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHP 491
               DPG   +      G R  D  +  R  D   G   +    G       G P P G  
Sbjct: 1271 FPGDPGPPGEG-----GPRGQDGAKGDRGEDGEPGQPGSPGPTGEN-----GPPGPLG-- 1318

Query: 492  KAGHSENGVEEDTEGRTGPK--EGTPGSPSETPGPSPAGPAGDEPAESPSETPG------ 543
            K G + +   E  +G  G K   G  G+P +T    PAGPAG    +     PG      
Sbjct: 1319 KRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQG 1378

Query: 544  -PRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG-------PSPAGPTRDEPA 595
             P   G AG      P   PG R     GD  A+     PG       P   G   D   
Sbjct: 1379 RPGATGQAGPPGPVGPPGLPGLR-----GDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGL 1433

Query: 596  ESPSETPGPR----------PAGPAGDEPAESPSETPGPR----PAGPAGDEPAESPSET 641
              P  +PG +          P GP G      P+   G +    P GP G++  + P   
Sbjct: 1434 PGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGH 1493

Query: 642  PGP 644
            PGP
Sbjct: 1494 PGP 1496



 Score = 57.4 bits (137), Expect = 4e-08
 Identities = 108/407 (26%), Positives = 138/407 (33%), Gaps = 70/407 (17%)

Query: 314 GSPGDPDHEASTQGRTCGPEHSKGGGRVDEGP-QPRSVEPQDAGP--LERSQGDEA---- 366
           G PG+  H   T  +       + G R D+G   PR + P ++GP  L   +G       
Sbjct: 565 GLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGL-PGESGPRGLLGPKGPPGIPGP 623

Query: 367 -GGHGEDRPEPLSPKESKKRKLELSRREQPPTE-----PGPQSA-----SEVEKIALNLE 415
            G  G D P+   PK S   + E     Q  T      PGPQ A      +  +    L 
Sbjct: 624 PGVRGMDGPQ--GPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLP 681

Query: 416 GCALSQGSLRTGTQE-----VGGQDPGEAVQPCRQ--PLGARVADKVR--KRRKVDEGAG 466
           G   S G      +E      G Q P     P     P G +  D +R  K  K ++G  
Sbjct: 682 GMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGED 741

Query: 467 DSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGP--------------KE 512
                  G    + + G     G P     E+G  E  +GRTGP              K 
Sbjct: 742 G----FPGFKGDIGVKGDRGEVGVP-GSRGEDG-PEGPKGRTGPTGDPGPPGLMGEKGKL 795

Query: 513 GTPGSPSETPGPSPAGPAGDEPAESPSETPGPR----PAGPAGDEPAESPSETPGPRPA- 567
           G PG P       P G  G       S   G R     +GP G+     P    GPR A 
Sbjct: 796 GVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGAT 855

Query: 568 -------GPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPG----PRPAGPAGDEPAE 616
                     GD P   P E   P P GP      + P   PG    P   G  G+   +
Sbjct: 856 GKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQ 915

Query: 617 SPSETPG-PRPAGPAGDEPAESP-SETPGPSPAGPTRDE--PAKAGE 659
             +  PG P   GP G      P  E   P P GP  ++  P  AG+
Sbjct: 916 GKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGK 962



 Score = 57.0 bits (136), Expect = 6e-08
 Identities = 92/363 (25%), Positives = 124/363 (34%), Gaps = 81/363 (22%)

Query: 325 TQGRTCGPEHSKGGGRVDEGPQPRSV-------EPQDAGPLERSQGDEAGG--HGEDRPE 375
           T  R    E+ +GG    EGP   +        E  + GP   ++   +G   HG   P 
Sbjct: 323 TADRFQAEEYGEGGTDPPEGPYDYTYGYGDDYREETELGPALSAETAHSGAAAHG---PR 379

Query: 376 PLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGGQD 435
            L  ++ +   LE     + P  PGP+  + +           +    ++     VG  D
Sbjct: 380 GLKGEKGEPAVLEPGMLVEGP--PGPEGPAGL-----------IGPPGIQGNPGPVG--D 424

Query: 436 PGEAVQPCRQPLGAR------VADKVRKRRKVDEGAGDSA-AVASGGAQT--------LA 480
           PGE   P R  L             +    +   G GD    VA+  AQ         LA
Sbjct: 425 PGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLA 484

Query: 481 LAGSPAPSGHPKAGHSENGVEEDTEGRTGP--KEGTPGSPSETPGPSPAGPAGDEPAESP 538
           L G P P G+               GR GP  + G+PG   E+    P GP G +    P
Sbjct: 485 LRGPPGPMGYT--------------GRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGP 530

Query: 539 SETPGPRPAGPAGDEPAESPSETPG-------------PRPAGPAGDEPAESPSETPGPS 585
               G R  G AG + A      PG             P   G  GD  A+     PG  
Sbjct: 531 PGKAGRR--GRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGED 588

Query: 586 PAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPA----GPAGDEPAESPSET 641
             G   D+    P   PG   +GP G    + P   PGP       GP G + +  P   
Sbjct: 589 --GERGDDGEIGPRGLPG--ESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGE 644

Query: 642 PGP 644
           PGP
Sbjct: 645 PGP 647


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score = 80.9 bits (198), Expect = 4e-15
 Identities = 80/265 (30%), Positives = 89/265 (33%), Gaps = 48/265 (18%)

Query: 453  DKVRKRRKVDEGAGDSAAVASGGAQTLALAG-------SPAPSGHPKAGHSENGVEEDTE 505
            D V+    VD+G     AV SG A  L  A         P P   PK    E G E    
Sbjct: 1208 DSVQTFFAVDDGPSLDQAV-SGLATALCQASFTTQPRPEPCPVYCPKGQKGEPG-EMGLR 1265

Query: 506  GRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPG-------PRPAGPAGDEPAESP 558
            G+ GP  G PG P  T  P P GP G   A+     PG       P  AG  G   A   
Sbjct: 1266 GQVGPP-GDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGL 1324

Query: 559  SETPG-PRPAGPAGDEPAESPSETPG-------------------------PSPAGPTRD 592
              +PG P P G  G+     P   PG                         P P GP  D
Sbjct: 1325 KGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGD 1384

Query: 593  EPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRD 652
                 P   PG    G  GD     P   PGP   G A  EP   P     P P GP   
Sbjct: 1385 PGPRGPPGLPGTAMKGDKGDRGERGP---PGPGEGGIAPGEPG-LPGLPGSPGPQGPV-G 1439

Query: 653  EPAKAGEAAELQDAEVESSAKSGKP 677
             P K GE  + +D       + G P
Sbjct: 1440 PPGKKGEKGDSEDGAPGLPGQPGSP 1464



 Score = 73.9 bits (180), Expect = 4e-13
 Identities = 65/229 (28%), Positives = 82/229 (35%), Gaps = 36/229 (15%)

Query: 483  GSPAPSGHP-----KAGHSENGVEEDTEGRTGPK-EGTPGSPSETPGPSPAGPAGDEPAE 536
            G P P G P     +    E G      G  GP   G  G P  +  P P GP GD    
Sbjct: 1329 GLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPR 1388

Query: 537  SPSETPGPRPAGPAGDE-------PAE---SPSE--------TPGPR-PAGPAGDEPAES 577
             P   PG    G  GD        P E   +P E        +PGP+ P GP G +  + 
Sbjct: 1389 GPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKG 1448

Query: 578  PSETPGPSPAGPTRDEPAESPSETPG----------PRPAGPAGDEPAESPSETPGPRP- 626
             SE   P   G       + P   PG          P P G AG++    P    G R  
Sbjct: 1449 DSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGL 1508

Query: 627  AGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDAEVESSAKSG 675
             G AG   A+ P   PGP+     + EP + G+ A +  A      + G
Sbjct: 1509 PGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKG 1557



 Score = 69.7 bits (169), Expect = 8e-12
 Identities = 111/419 (26%), Positives = 143/419 (34%), Gaps = 70/419 (16%)

Query: 287  GPQDKLRRFKPSSLPHPLEGSRKVEEEGSPGDPDHEA--STQGR--TCGPEHSKG--GGR 340
            GP   +        P PL  + +  E G PG           GR    GPE   G  G +
Sbjct: 1471 GPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQ 1530

Query: 341  VDEGPQPRSVEPQDAGPLERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPG 400
             ++G   R  +P   GP       E G  G   P   +  + ++    L      P +PG
Sbjct: 1531 GEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVL----PGDPG 1586

Query: 401  PQSASEVEKIALNLEGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRK 460
            P+     ++  + L G A   G   +G     G DPG    P   P+G R  D      K
Sbjct: 1587 PKG-DPGDRGPIGLTGRAGPPGD--SGPPGEKG-DPGRPGPP--GPVGPRGRDG-EVGEK 1639

Query: 461  VDEGA-GDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPS 519
             DEG  GD       G +   L G+P   G                G  G  +G PG   
Sbjct: 1640 GDEGPPGDPGLPGKAGER--GLRGAPGVRG--------------PVGEKGD-QGDPGEDG 1682

Query: 520  ETPGPSPAGPAGDEPAESPSETPGPR-PAGPAGDEPAESPSETPGPRPAGPAGDEPAESP 578
                P  +GP GD     P   PG     GP   E  E P +     P GP GD     P
Sbjct: 1683 RNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGE-PGDRGQEGPRGPKGD-----P 1736

Query: 579  SETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPG-------PRPAGPAG 631
                 P   G         P   PG R  GPAG++    P    G       P  AGP+G
Sbjct: 1737 GLPGAPGERGIEGFRGPPGPQGDPGVR--GPAGEKGDRGPPGLDGRSGLDGKPGAAGPSG 1794

Query: 632  DEPAESPSETPG-------------PSPAGPTRDEPAKAGEAAELQDAEVESSAKSGKP 677
               A   +  PG             P P+GP    P K GE     D +   + K+G+P
Sbjct: 1795 PNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPP-GLPGKPGE-----DGKPGLNGKNGEP 1847



 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 109/384 (28%), Positives = 136/384 (35%), Gaps = 48/384 (12%)

Query: 312  EEGSPGDP----------DHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERS 361
            + G PGDP          D  AS +    GP+  +G   +  GPQ     P   GP  + 
Sbjct: 1843 KNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGI-LGPQGPPGLPGPVGPPGQG 1901

Query: 362  QGDEAGGHGE--DRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALN-----L 414
                 GG G   DR E  S K  +    E   R +P + P      E   I  +     +
Sbjct: 1902 FPGVPGGTGPKGDRGETGS-KGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIV 1960

Query: 415  EGCALSQGSLRTGTQEVGGQ--DPGEAVQPCRQ-PLGARVADKVRKRRKVDEGAGDSAAV 471
            E    S GS     +   G   D GE   P ++ P+G    ++  K  + D G      +
Sbjct: 1961 ETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFP-GERGLKGDRGDPGPQGPPGL 2019

Query: 472  A---SGGAQTLALAGSPAPSGHP----------KAGHSENGVEEDTEGRTGP--KEGTPG 516
            A    G      LAG P   G P          +AG      E   +G  G   ++G PG
Sbjct: 2020 ALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPG 2079

Query: 517  SPSETPGPSPAGP--AGDEPAESPSETPGPRPAGPAGDEPAESPSETP-GPRPA-GPAGD 572
             P     P P GP  + DEP    S   GP     A  EP  +  + P G R   G  GD
Sbjct: 2080 LPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGD 2139

Query: 573  EPAESPSETPG-PSPAGPTRDEPAESPSETPGPR-PAGPAGDEPAESPSETPG-PRPAGP 629
                 P    G P   G       E      GPR P GP G      P   PG   PAGP
Sbjct: 2140 RGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGP 2199

Query: 630  AGDEPAE-SPSET--PGPSPAGPT 650
             G    +  P ET  PG    GPT
Sbjct: 2200 QGPSGLKGEPGETGPPGRGLTGPT 2223



 Score = 63.9 bits (154), Expect = 5e-10
 Identities = 111/411 (27%), Positives = 134/411 (32%), Gaps = 118/411 (28%)

Query: 312  EEGSPGDPDHEASTQGRTCGPEHSKG-----------GGRVDEGPQPRSVEPQDAGPLER 360
            E+G PG P   A       GP+  KG           G + + GP P  V P D GP + 
Sbjct: 1532 EKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGP-PGLVLPGDPGP-KG 1589

Query: 361  SQGD--------------EAGGHGED----RPEPLSPKESKKRKLELSRR--EQPPTEPG 400
              GD              ++G  GE     RP P  P   + R  E+  +  E PP +PG
Sbjct: 1590 DPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPG 1649

Query: 401  -PQSASEVEKIALNLEGCALSQGSLRTGTQEVGGQ-DPGEAVQPCRQPLGARVADKVRKR 458
             P  A E       L G       +R    E G Q DPGE                    
Sbjct: 1650 LPGKAGE-----RGLRGAP----GVRGPVGEKGDQGDPGE-------------------- 1680

Query: 459  RKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKA------GHSENGVEEDT--EGRTGP 510
                    D    + G +      G P P G P        G  E G   D   EG  GP
Sbjct: 1681 --------DGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGP 1732

Query: 511  K--EGTPGSPSETPGPS---PAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPR 565
            K   G PG+P E        P GP GD     P+   G R  GP G +        PG  
Sbjct: 1733 KGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDR--GPPGLDGRSGLDGKPGA- 1789

Query: 566  PAGPAGDEPAESPSETPG-------------PSPAGP--TRDEPAE-----------SPS 599
             AGP+G   A   +  PG             P P+GP     +P E            P 
Sbjct: 1790 -AGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPG 1848

Query: 600  ETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG-PSPAGP 649
            +       G  GD  A       GP+  G  G      P   PG P P GP
Sbjct: 1849 DPGEDGRKGEKGDSGASGREGRDGPK--GERGAPGILGPQGPPGLPGPVGP 1897



 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 106/390 (27%), Positives = 138/390 (35%), Gaps = 59/390 (15%)

Query: 310  VEEEGSPGDPDHEASTQGRTCGPEHS-KGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGG 368
            V E+G  GDP  +    GR   P  S   G R + GP        D GP  R +G E G 
Sbjct: 1669 VGEKGDQGDPGED----GRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKG-EPGD 1723

Query: 369  HGEDRP-----EPLSPKESKKRKLELSRREQPPT-EPGPQ--SASEVEKIALNLEGCALS 420
             G++ P     +P  P    +R +E  R    P  +PG +  +  + ++    L+G +  
Sbjct: 1724 RGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGL 1783

Query: 421  QGSLRTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTL- 479
             G              G+A  P R  L       +R  + +   +G        G     
Sbjct: 1784 DGKPGAAGPSGPNGAAGKAGDPGRDGLPG-----LRGEQGLPGPSGPPGLPGKPGEDGKP 1838

Query: 480  ALAGSPAPSGHP----KAGHSENGVEEDTEGRTGPK--EGTPG--SPSETPG-PSPAGPA 530
             L G     G P    + G   +      EGR GPK   G PG   P   PG P P GP 
Sbjct: 1839 GLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPP 1898

Query: 531  GDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPS-----ETPGPS 585
            G      P    G  P G  G+  ++     PG R  G  G EP   P+     ET G  
Sbjct: 1899 GQG---FPGVPGGTGPKGDRGETGSKGEQGLPGER--GLRG-EPGSVPNVDRLLETAGIK 1952

Query: 586  PAG-----PTRDEPAESPSETPGPRPAGPAGDEPAESPSETPG----PRPAGPAGDEPAE 636
             +       T DE + S    P  R  GP GD   + P    G    P   G  GD    
Sbjct: 1953 ASALREIVETWDESSGSFLPVP-ERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDP 2011

Query: 637  SPSETPG--------PSPAGPTRDEPAKAG 658
             P   PG        P P+G    EP K G
Sbjct: 2012 GPQGPPGLALGERGPPGPSG-LAGEPGKPG 2040



 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 105/401 (26%), Positives = 123/401 (30%), Gaps = 75/401 (18%)

Query: 287  GPQDKLRRFKPSSLPHPLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQ 346
            GP+ K     P   P P+ G       G PG P   A       GP+          GP 
Sbjct: 2162 GPEGKPGLQGPRGPPGPVGG------HGDPGPPG--APGLAGPAGPQ----------GPS 2203

Query: 347  PRSVEPQDAGPLERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPG-PQSAS 405
                EP + GP  R      G  G   P P  P          S    P   PG P    
Sbjct: 2204 GLKGEPGETGPPGRGLTGPTGAVG--LPGPPGP----------SGLVGPQGSPGLPGQVG 2251

Query: 406  EVEKI-ALNLEGCALSQGSLRTGTQEVGGQ-----------DPGEAVQPCRQPLGARVAD 453
            E  K  A   +G +   G    G+  V G            +PG    P +  +G   A 
Sbjct: 2252 ETGKPGAPGRDGASGKDGD--RGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGA- 2308

Query: 454  KVRKRRKVDEGA-GDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKE 512
                  K ++GA G  A    G        G P P G           E+   GR G + 
Sbjct: 2309 ------KGEKGAPGGLAGDLVGEPGAKGDRGLPGPRG-----------EKGEAGRAG-EP 2350

Query: 513  GTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG----PRPAG 568
            G PG   +   P P G  GD     P     P P G  GD         PG    P   G
Sbjct: 2351 GDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTG 2410

Query: 569  PAGDEPAESPSETPGPSPAGPTRDEPAESPSETPG-PRPAGPAGDEPAESPSETPG---P 624
            P G+     PS   G   AGP   E    P   PG P   GP G    +     PG   P
Sbjct: 2411 PRGEMGQPGPSGERG--LAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLP 2468

Query: 625  RPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQD 665
             P G  G+         PG          P   GE  E  D
Sbjct: 2469 GPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGD 2509



 Score = 57.0 bits (136), Expect = 6e-08
 Identities = 63/220 (28%), Positives = 78/220 (35%), Gaps = 30/220 (13%)

Query: 483  GSPAPSGH--PKAGHSENGVEEDTEGRTGPK--EGTPGSPSET-----------PGP-SP 526
            G P  +G   PK      G++ D  G  GP+  +G PG P E             GP  P
Sbjct: 2117 GEPGSNGDQGPKGDRGVPGIKGD-RGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGP 2175

Query: 527  AGPAGDEPAESPSETPG-PRPAGPAGDEPAES-PSETPGPR-----PAGPAGDEPAESPS 579
             GP G      P   PG   PAGP G    +  P ET  P      P G  G      PS
Sbjct: 2176 PGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPS 2235

Query: 580  ETPGP--SPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPG-PRPAGPAGDEPAE 636
               GP  SP  P +      P        +G  GD  +     +PG P P GP G+    
Sbjct: 2236 GLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEP--- 2292

Query: 637  SPSETPGPSPAGPTRDEPAKAGEAAELQDAEVESSAKSGK 676
             P+  PG +  G    +  K        D   E  AK  +
Sbjct: 2293 GPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDR 2332



 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 98/370 (26%), Positives = 125/370 (33%), Gaps = 74/370 (20%)

Query: 313  EGSPGDPDHEASTQGRTCGPEHSKG--GGRVDEG-PQPRSVEPQDAGPLERSQGDEAGGH 369
            +G+ G+P           GP+  +G  G + D G P PR  +     P ER      G  
Sbjct: 2113 KGAKGEPGSNGDQ-----GPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKP 2167

Query: 370  GEDRPE-PLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGT 428
            G   P  P  P                  +PGP  A         L G A  QG   +G 
Sbjct: 2168 GLQGPRGPPGPVGGHG-------------DPGPPGAP-------GLAGPAGPQGP--SGL 2205

Query: 429  QEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPS 488
            +     +PGE   P R   G   A  +          G S  V   G+    L G    +
Sbjct: 2206 KG----EPGETGPPGRGLTGPTGAVGL------PGPPGPSGLVGPQGSP--GLPGQVGET 2253

Query: 489  GHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPR--- 545
            G P A   +    +D +  +    G+PG P         GP G  P ++    PG +   
Sbjct: 2254 GKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTG-APGQAVVGLPGAKGEK 2312

Query: 546  --PAGPAGD---EP-AESPSETPGPR----PAGPAGD--EPAESPSETPGPSPAGPTRDE 593
              P G AGD   EP A+     PGPR     AG AG+  +P E   +   P P G   D 
Sbjct: 2313 GAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGED-GQKGAPGPKGFKGDP 2371

Query: 594  PAESPSETPGPRPAGPAGDEPAESPSETPG----PRPAGPAGDEPAESPSETPG------ 643
                P     P P G  GD         PG    P   GP G+     PS   G      
Sbjct: 2372 GVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPG 2431

Query: 644  ----PSPAGP 649
                P P GP
Sbjct: 2432 REGIPGPLGP 2441



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 57/198 (28%), Positives = 71/198 (35%), Gaps = 23/198 (11%)

Query: 483  GSPAPSGHPKAGHSENGV----EEDTEGRTGPK-----EGTPGSPSETPGPSPAGPAGDE 533
            GSP   G P     +  V        +G  G K     +G  G   E   P   G AG +
Sbjct: 2599 GSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHK 2658

Query: 534  PAESPSETPGPRPAGPAGDEPAESPSETPG-PRPAGPAGDEPAESPSETPG----PSPAG 588
                    PG   +G  G E    P    G     GP GD+  +    TPG    P P+G
Sbjct: 2659 GEMGEPGVPGQ--SGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSG 2716

Query: 589  PTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG-PSPA 647
                     P  + GPR  GP G +  +     PG R  G  G   A       G P PA
Sbjct: 2717 NDGSAGPPGPPGSVGPR--GPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPA 2774

Query: 648  GPTRDEPAKAGEAAELQD 665
            GP  ++    GEAA  +D
Sbjct: 2775 GPRGEK----GEAALTED 2788



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 113/441 (25%), Positives = 138/441 (31%), Gaps = 108/441 (24%)

Query: 312  EEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDE-----A 366
            E+G PGD   E        GP   KG   +   P  R +E     P    QGD      A
Sbjct: 1717 EKGEPGDRGQE--------GPRGPKGDPGLPGAPGERGIEGFRGPP--GPQGDPGVRGPA 1766

Query: 367  GGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLR- 425
            G  G+  P  L  +      L+       P+ P   +    +     L G    QG    
Sbjct: 1767 GEKGDRGPPGLDGRSG----LDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGP 1822

Query: 426  TGTQEVGGQDPGEAVQPCRQPLGARVADKV---RKRRKVDEGA----------GDSAAVA 472
            +G   + G+ PGE  +P          D     RK  K D GA          G+  A  
Sbjct: 1823 SGPPGLPGK-PGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPG 1881

Query: 473  SGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPK--EGTPGSPSETPGPSPAGPA 530
              G Q     G P P G P  G           G TGPK   G  GS  E   P   G  
Sbjct: 1882 ILGPQ--GPPGLPGPVGPPGQGFP------GVPGGTGPKGDRGETGSKGEQGLPGERGLR 1933

Query: 531  GDEPAESPS-----ETPG------------------------PRPAGPAGDEPAESPSET 561
            G EP   P+     ET G                         R  GP GD   + P   
Sbjct: 1934 G-EPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGK 1992

Query: 562  PGP----RPAGPAGDEPAESPSETPGPS-----PAGPT--RDEPAE-------------S 597
             GP       G  GD     P   PG +     P GP+    EP +              
Sbjct: 1993 EGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVG 2052

Query: 598  PSETPGPR----PAGPAGDEPAESPSETPG-PRPAGPAG-----DEPAESPSETPGPSPA 647
             +  PG R      G  G++  + P   PG P P GP G     DEP    S   GP   
Sbjct: 2053 EAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGL 2112

Query: 648  GPTRDEPAKAGEAAELQDAEV 668
               + EP   G+     D  V
Sbjct: 2113 KGAKGEPGSNGDQGPKGDRGV 2133



 Score = 38.1 bits (87), Expect = 0.027
 Identities = 40/143 (27%), Positives = 50/143 (34%), Gaps = 8/143 (5%)

Query: 435  DPGEAVQPCRQPLGARVADKVRKRRKVDEGA-GDSAAVASGGAQTLALAGSPAPSGHPKA 493
            D GEA  P R  L     +          GA G    +   G +     G P P G  + 
Sbjct: 2642 DKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDR--GFDGQPGPKGD-QG 2698

Query: 494  GHSENGVEEDTEGRTGPK--EGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAG 551
               E G      G  GP   +G+ G P       P GP G +  +     PG R  G  G
Sbjct: 2699 EKGERGTP-GIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPG 2757

Query: 552  DEPAESPSETPG-PRPAGPAGDE 573
               A       G P PAGP G++
Sbjct: 2758 VPGAPGERGEQGRPGPAGPRGEK 2780



 Score = 32.0 bits (71), Expect = 1.9
 Identities = 58/246 (23%), Positives = 80/246 (32%), Gaps = 50/246 (20%)

Query: 312  EEGSPGDPDHEASTQ----GRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAG 367
            ++GS G+P  + S          GP+   G   +   P       +D  P  R +  + G
Sbjct: 2561 DKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPG---KDGVPGIRGEKGDVG 2617

Query: 368  GHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTG 427
              G   P  L  +   K    L   +    E GP              G A  +G +  G
Sbjct: 2618 FMG---PRGLKGERGVKGACGLDGEKGDKGEAGPPGRP----------GLAGHKGEM--G 2662

Query: 428  TQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAP 487
               V GQ      +    P G R  D  +   K D+G         G   T  + G P P
Sbjct: 2663 EPGVPGQSGAPGKEGLIGPKGDRGFDG-QPGPKGDQGE-------KGERGTPGIGGFPGP 2714

Query: 488  SGH--------PKAGHSENGVE--EDTEGRTGPK----------EGTPGSPSETPGPSPA 527
            SG+        P       G E  +  +G  GP            G PG   E   P PA
Sbjct: 2715 SGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPA 2774

Query: 528  GPAGDE 533
            GP G++
Sbjct: 2775 GPRGEK 2780


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score = 79.7 bits (195), Expect = 8e-15
 Identities = 112/381 (29%), Positives = 139/381 (36%), Gaps = 63/381 (16%)

Query: 297  PSSLPHPLEGSRKVEEEGSPGDPDHEAST--QGRTCGPEHSKGGGRVDEGPQPRSVEPQD 354
            P   P P        ++G PG P     T  QG+T  P    G G V  GPQ  + E   
Sbjct: 938  PVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPP----GPGGV-VGPQGPTGE--- 989

Query: 355  AGPL-ERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALN 413
             GP+ ER      G  GE      + KE  K             +PGPQ  S  +  A  
Sbjct: 990  TGPIGERGHPGPPGPPGEQGLPGAAGKEGAKG------------DPGPQGISGKDGPA-G 1036

Query: 414  LEGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVAS 473
            L G    +G    G Q   G   GE  Q    P+G+              G   SA    
Sbjct: 1037 LRGFPGERGL--PGAQGAPGLKGGEGPQGPPGPVGS-------------PGERGSA---- 1077

Query: 474  GGAQTLALAGSPAPSGHP-KAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPS-PAGPAG 531
            G A  + L G P P G P  AG      E+  +G  G ++G  G P   PGP+ PAG  G
Sbjct: 1078 GTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAG-RDGVQG-PVGLPGPAGPAGSPG 1135

Query: 532  DEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGP----SPA 587
            ++  +     PG +  G  GD+    P   PG +  GP G          PGP       
Sbjct: 1136 EDGDKGEIGEPGQK--GSKGDKGENGPPGPPGLQ--GPVGAPGIAGGDGEPGPRGQQGMF 1191

Query: 588  GPTRDEPAESPSETPG-------PRPAGPAGDEPAESPSETPG-PRPAGPAGDEPAESPS 639
            G   DE A      PG       P P G  G+     P   PG P P GP G   A+ P 
Sbjct: 1192 GQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQ 1251

Query: 640  ETPGPSPAGPTRDEPAKAGEA 660
              PG   +     E  + GEA
Sbjct: 1252 GPPGSVGSVGGVGEKGEPGEA 1272



 Score = 69.7 bits (169), Expect = 8e-12
 Identities = 121/422 (28%), Positives = 150/422 (35%), Gaps = 80/422 (18%)

Query: 310  VEEEGSPGDPDHEASTQGR--TCGPEHSKGGGRVDEGPQPRSVEPQDAG----PLER--- 360
            + E G PG P      QG     G E +KG    D GPQ  S +   AG    P ER   
Sbjct: 993  IGERGHPGPPGPPGE-QGLPGAAGKEGAKG----DPGPQGISGKDGPAGLRGFPGERGLP 1047

Query: 361  -SQGDEAGGHGEDRPEPLSPKESKKRK--------LELSRREQPPTEPGPQSASEVEKIA 411
             +QG      GE    P  P  S   +        + L  R  P   PGP      EK A
Sbjct: 1048 GAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAG----EKGA 1103

Query: 412  LNLEGCALSQGSLRTGTQ-EVGGQDP-GEAVQPCRQPLGARVADKVRKRRKVDEGA---- 465
               +G     G  R G Q  VG   P G A  P        + +  +K  K D+G     
Sbjct: 1104 PGEKGPQGPAG--RDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPP 1161

Query: 466  GDSAAVASGGAQTLALA-GSPAPSGHPKAGHSENGVEEDTEGRTGPK-----EGTPGSPS 519
            G        GA  +A   G P P G  + G      +E   G  GP      +G PG P 
Sbjct: 1162 GPPGLQGPVGAPGIAGGDGEPGPRG--QQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPG 1219

Query: 520  ETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGP-RPAGPAGDEPAESP 578
            E       GP G      P   PGPR  GP G   A+ P   PG     G  G++     
Sbjct: 1220 EKGENGDVGPMG------PPGPPGPR--GPQGPNGADGPQGPPGSVGSVGGVGEKGEPGE 1271

Query: 579  SETPGP-------SPAGPTRDEPAESPSETPGPRPA-GPAGDE-PAESPSETPGPRPAGP 629
            +  PGP        P G   ++    P    GP  A GP GD+ P  +P     P   GP
Sbjct: 1272 AGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGP 1331

Query: 630  AGDEPAESPSETPG-----------PSPAGPTRD-----EPAKAGE--AAELQDAEVESS 671
             G EP  +  +  G           P P GP+ +      P K G   AA  +  + E  
Sbjct: 1332 PG-EPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKG 1390

Query: 672  AK 673
            AK
Sbjct: 1391 AK 1392



 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 98/359 (27%), Positives = 120/359 (33%), Gaps = 77/359 (21%)

Query: 359  ERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQS-ASEVEKIAL-NLEG 416
            +R +  + G  GED PE   PK           R  P  +PGP   A E  K+ +  L G
Sbjct: 809  DRGEVGQIGPRGEDGPE--GPKG----------RAGPTGDPGPSGQAGEKGKLGVPGLPG 856

Query: 417  CALSQGSLRT----GTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVA 472
                QG   +    G     G+     V     P G R     R  R      G      
Sbjct: 857  YPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKG 916

Query: 473  SGGAQTLALAGSPAPSGH--PKAGHSENGVEEDTEGRTGP--KEGTPGSPSET------- 521
            + G       G P P G   P+      G     +G  GP  K+G PG P +        
Sbjct: 917  TSGGD-----GPPGPPGERGPQGPQGPVGFP-GPKGPPGPPGKDGLPGHPGQRGETGFQG 970

Query: 522  ----PGPS----PAGPAGDEPAESPSETPGPRPAGPAGDEPA------ESPSETPGPRPA 567
                PGP     P GP G+         PGP   GP G++        E     PGP+  
Sbjct: 971  KTGPPGPGGVVGPQGPTGETGPIGERGHPGP--PGPPGEQGLPGAAGKEGAKGDPGPQGI 1028

Query: 568  ----GPAGDE--PAE--------SPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDE 613
                GPAG    P E        +P    G  P GP    P  SP E      AGP G  
Sbjct: 1029 SGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPG--PVGSPGERGSAGTAGPIGLP 1086

Query: 614  PAESPSETPGPR----------PAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAE 662
                P   PGP           P GPAG +  + P   PGP+    +  E    GE  E
Sbjct: 1087 GRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGE 1145



 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 113/424 (26%), Positives = 145/424 (34%), Gaps = 65/424 (15%)

Query: 288  PQDKLRRFK--PSSLPHPL--EGSRKVEEEGSPGDPDHEASTQGR-----TCGPEHSKGG 338
            P DK  R +  P   P P   +G R  + E  P     EA  +G      T G     G 
Sbjct: 621  PGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGM 680

Query: 339  GRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGEDRPE-PLSPK-----ESKKRKLELSRR 392
              VD  P P+        P    Q    G  G   P+ P+ P      + K     L   
Sbjct: 681  AGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGA 740

Query: 393  EQPPTEPGPQSASEVEKIALNLEGCALSQGSLR-TGTQEVGGQDPGEAVQPCRQPLGARV 451
            + PP  PG +  S  EK AL   G    QG +   G + V G D    ++  +   G   
Sbjct: 741  DGPPGHPGKEGQSG-EKGALGPPG---PQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDG 796

Query: 452  ADKVRKRRKVDEGAGDSAAVASGGAQ-------TLALAGSPAPSGHPKAGHSEN-GVE-- 501
                +    +    G+   +   G              G P PSG  +AG     GV   
Sbjct: 797  FPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSG--QAGEKGKLGVPGL 854

Query: 502  EDTEGRTGPKEGT--PGSPSET-----------PGP----SPAGPAGDEPAESPSETPGP 544
                GR GPK  T  PG P              PGP     P GP G   A  P+  PGP
Sbjct: 855  PGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGP 914

Query: 545  RPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG----PSPAGPTRDEPAESPSE 600
            +     GD P   P E     P GP G    + P   PG    P   G   +   +  + 
Sbjct: 915  KGTS-GGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTG 973

Query: 601  TPGP----RPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG----PSPAGPT-R 651
             PGP     P GP G+         PG  P GP G++     +   G    P P G + +
Sbjct: 974  PPGPGGVVGPQGPTGETGPIGERGHPG--PPGPPGEQGLPGAAGKEGAKGDPGPQGISGK 1031

Query: 652  DEPA 655
            D PA
Sbjct: 1032 DGPA 1035



 Score = 66.6 bits (161), Expect = 7e-11
 Identities = 100/367 (27%), Positives = 128/367 (34%), Gaps = 56/367 (15%)

Query: 314  GSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGEDR 373
            GSPG+ D +    G   G + SKG    +  P P  ++     P        AGG GE  
Sbjct: 1132 GSPGE-DGDKGEIGEP-GQKGSKGDKGENGPPGPPGLQGPVGAP------GIAGGDGE-- 1181

Query: 374  PEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGG 433
            P P   +    +K +   R  P   PGP          + L+G     G  +    +VG 
Sbjct: 1182 PGPRGQQGMFGQKGDEGARGFPGP-PGP----------IGLQGLPGPPGE-KGENGDVGP 1229

Query: 434  QDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGH--- 490
              P     P R P G   AD  +         G    V   G      AG+P P G    
Sbjct: 1230 MGPPGPPGP-RGPQGPNGADGPQGP---PGSVGSVGGVGEKGEP--GEAGNPGPPGEAGV 1283

Query: 491  --PKAGHSENGVEEDTEGRTGPK--EGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRP 546
              PK    E G E    G  GP   +G PG       P P G  GD     P     P P
Sbjct: 1284 GGPKGERGEKG-EAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGD-----PGPPGEPGP 1337

Query: 547  AGPAGDEPAESPSETPG-PRPAGPAGDEPAESPSETPGPSPAGPTRDEPAE--SPSETPG 603
            AG  G    +     PG P P GP+G+     P    GP  A        E  +  E   
Sbjct: 1338 AGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGA 1397

Query: 604  PRPAGPAGDEPAESPSETPGPRP----AGPAGDE--PAESPSETPGPSPAGP-----TRD 652
              P G  G    + P+  PGP       GP G++  P  +  + P P P GP      + 
Sbjct: 1398 EGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGP-PGPMGPPGLPGLKG 1456

Query: 653  EPAKAGE 659
            +P   GE
Sbjct: 1457 DPGSKGE 1463



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 61/211 (28%), Positives = 77/211 (36%), Gaps = 28/211 (13%)

Query: 479 LALAGSPAPSGHPKA----GHSENGVEEDTEGRTGP--------KEGTPGSPSETPGPSP 526
           + L G P P G P +    G S +   +   G  GP        K G PG+      P  
Sbjct: 546 MGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGE 605

Query: 527 AGPAGDEPAESPSETPGPR----------PAGPAGDEPAESPSETPGPRPA-GPAGDEPA 575
            G  GD   +     PG +          P GP GD+         GPR   G AG    
Sbjct: 606 PGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGL 665

Query: 576 ESPSETPG-PSPAGPTRDEPAESPSETPGPR-PAGPAGDEPAESPSETPGPR-PAGPAGD 632
             P  TPG P   G    +    P    GP+   GP G +    P   PGP+ P GP G+
Sbjct: 666 LGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGE 725

Query: 633 E-PAESPSETPGPSPAGPTRDEPAKAGEAAE 662
           + P   P     P   GP    P K G++ E
Sbjct: 726 KGPQGKPGLAGLPGADGPP-GHPGKEGQSGE 755



 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 114/439 (25%), Positives = 145/439 (33%), Gaps = 105/439 (23%)

Query: 312  EEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGE 371
            E G PG P  +        GP  + G    D  P PR  +          +GDE      
Sbjct: 1157 ENGPPGPPGLQ--------GPVGAPGIAGGDGEPGPRGQQGMFG-----QKGDEGARGFP 1203

Query: 372  DRPEPLS------PKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLR 425
              P P+       P   K    ++     PP  PGP+        A   +G   S GS+ 
Sbjct: 1204 GPPGPIGLQGLPGPPGEKGENGDVGPMG-PPGPPGPRGPQGPNG-ADGPQGPPGSVGSVG 1261

Query: 426  TGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQ-------- 477
             G  E G  +PGEA  P   P G       +  R     AG   A    GA+        
Sbjct: 1262 -GVGEKG--EPGEAGNP--GPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGP 1316

Query: 478  -----TLALAGSPAPSGHPKAGHSENGV-----EEDTEGRTGP-----KEGTPGSPSETP 522
                  +   G P P G P     ++GV     E+   G+ GP     + G PG P +  
Sbjct: 1317 KGNPGPVGFPGDPGPPGEPGPA-GQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRG 1375

Query: 523  GPSPAGPAG---------DEPAESPSETPGP-RPAGPAGDEPAESPSETPGP-------- 564
             P  AG  G         +  AE P    GP  P GPAG    E     PGP        
Sbjct: 1376 PPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPG 1435

Query: 565  --------RPAGPAG------DEPAESPSETPG-------PSPAGPTRDEPAESPSETPG 603
                     P GP G      D  ++     PG       P   G   D        +PG
Sbjct: 1436 AAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPG 1495

Query: 604  -------PRPAGPAGDEPAESPSETPG-PRPAGPAGDEPAESPSETPGPSPAGPTRDEPA 655
                   P PAGP G      P   PG P P GP G++ +  P+   G S        P 
Sbjct: 1496 AKGDGGIPGPAGPLG------PPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1549

Query: 656  KAGEAAELQDAEVESSAKS 674
              GE   +Q   + SS K+
Sbjct: 1550 PPGEV--IQPLPILSSKKT 1566



 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 95/365 (26%), Positives = 121/365 (33%), Gaps = 81/365 (22%)

Query: 287  GPQDKLRRFKPSSLPHPLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQ 346
            GPQ       P   P  +     V E+G PG+  +         GP    G G    GP+
Sbjct: 1240 GPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNP--------GPPGEAGVG----GPK 1287

Query: 347  PRSVEPQDAGPLERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASE 406
                E  +AGP        AG  G   P      +     +       PP EPGP     
Sbjct: 1288 GERGEKGEAGP-----PGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQ-- 1340

Query: 407  VEKIALNLEGCALSQGSLRTGTQEVGGQDPGEAVQPC----RQPLGARVADKVRKRRKVD 462
                    +G    +G      Q       GEA  P     R P GA  A+     R+ +
Sbjct: 1341 --------DGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEG----RQGE 1388

Query: 463  EGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGP--KEGTPGSPSE 520
            +GA   A  A G        G   P+G P          E   G  GP  ++G PG+  +
Sbjct: 1389 KGAKGEAG-AEGPPGKTGPVGPQGPAGKPGP--------EGLRGIPGPVGEQGLPGAAGQ 1439

Query: 521  TPGPSPAGPAG------DEPAESPSETPG-------PRPAGPAGDEPAESPSETPG---- 563
               P P GP G      D  ++     PG       P   G  GD        +PG    
Sbjct: 1440 DGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGD 1499

Query: 564  ---PRPAGPAGDEPAESPSETPG-PSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPS 619
               P PAGP G      P   PG P P GP  ++ +  P        AG  GD     P 
Sbjct: 1500 GGIPGPAGPLG------PPGPPGLPGPQGPKGNKGSTGP--------AGQKGDSGLPGPP 1545

Query: 620  ETPGP 624
             +PGP
Sbjct: 1546 GSPGP 1550



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 52/184 (28%), Positives = 62/184 (33%), Gaps = 49/184 (26%)

Query: 513 GTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG--------- 563
           G PG    T  P P G  G   A+  S  PGP+  GP G +    P+  PG         
Sbjct: 541 GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQ--GPRGVQGPPGPTGKPGKRGRPGADG 598

Query: 564 ----PRPAGPAGDEPAESPSETPG----------PSPAGPTRDE--------------PA 595
               P   G  GD   +     PG            P GP  D+              P 
Sbjct: 599 GRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPG 658

Query: 596 ES-------PSETPG-PRPAGPAGDEPAESPSETPGPR-PAGPAGDEPAESPSETPGP-S 645
           E+       P  TPG P   G AG +    P    GP+   GP G +    P   PGP  
Sbjct: 659 EAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQG 718

Query: 646 PAGP 649
           P GP
Sbjct: 719 PIGP 722



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 56/192 (29%), Positives = 68/192 (35%), Gaps = 31/192 (16%)

Query: 483 GSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETP 542
           G PA +   +   + +G   +   +  P    PG   E P P PAGPAG      P    
Sbjct: 416 GVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGP-PGPAGPAG---IMGPPGLQ 471

Query: 543 GPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAES---PSETPGPSPAGPTRD-EPAESP 598
           GP   GP GD     P   PG   A      P      P    G    GPT   + A++ 
Sbjct: 472 GP--TGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQ 529

Query: 599 SETPGPR-----PAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGP-------SP 646
           +     R     P GP G         T  P P G  G   A+  S  PGP        P
Sbjct: 530 AILQQARIALRGPPGPMG--------LTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGP 581

Query: 647 AGPTRDEPAKAG 658
            GPT  +P K G
Sbjct: 582 PGPT-GKPGKRG 592


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score = 79.7 bits (195), Expect = 8e-15
 Identities = 112/381 (29%), Positives = 139/381 (36%), Gaps = 63/381 (16%)

Query: 297  PSSLPHPLEGSRKVEEEGSPGDPDHEAST--QGRTCGPEHSKGGGRVDEGPQPRSVEPQD 354
            P   P P        ++G PG P     T  QG+T  P    G G V  GPQ  + E   
Sbjct: 887  PVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPP----GPGGV-VGPQGPTGE--- 938

Query: 355  AGPL-ERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALN 413
             GP+ ER      G  GE      + KE  K             +PGPQ  S  +  A  
Sbjct: 939  TGPIGERGHPGPPGPPGEQGLPGAAGKEGAKG------------DPGPQGISGKDGPA-G 985

Query: 414  LEGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVAS 473
            L G    +G    G Q   G   GE  Q    P+G+              G   SA    
Sbjct: 986  LRGFPGERGL--PGAQGAPGLKGGEGPQGPPGPVGS-------------PGERGSA---- 1026

Query: 474  GGAQTLALAGSPAPSGHP-KAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPS-PAGPAG 531
            G A  + L G P P G P  AG      E+  +G  G ++G  G P   PGP+ PAG  G
Sbjct: 1027 GTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAG-RDGVQG-PVGLPGPAGPAGSPG 1084

Query: 532  DEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGP----SPA 587
            ++  +     PG +  G  GD+    P   PG +  GP G          PGP       
Sbjct: 1085 EDGDKGEIGEPGQK--GSKGDKGENGPPGPPGLQ--GPVGAPGIAGGDGEPGPRGQQGMF 1140

Query: 588  GPTRDEPAESPSETPG-------PRPAGPAGDEPAESPSETPG-PRPAGPAGDEPAESPS 639
            G   DE A      PG       P P G  G+     P   PG P P GP G   A+ P 
Sbjct: 1141 GQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQ 1200

Query: 640  ETPGPSPAGPTRDEPAKAGEA 660
              PG   +     E  + GEA
Sbjct: 1201 GPPGSVGSVGGVGEKGEPGEA 1221



 Score = 69.7 bits (169), Expect = 8e-12
 Identities = 121/422 (28%), Positives = 150/422 (35%), Gaps = 80/422 (18%)

Query: 310  VEEEGSPGDPDHEASTQGR--TCGPEHSKGGGRVDEGPQPRSVEPQDAG----PLER--- 360
            + E G PG P      QG     G E +KG    D GPQ  S +   AG    P ER   
Sbjct: 942  IGERGHPGPPGPPGE-QGLPGAAGKEGAKG----DPGPQGISGKDGPAGLRGFPGERGLP 996

Query: 361  -SQGDEAGGHGEDRPEPLSPKESKKRK--------LELSRREQPPTEPGPQSASEVEKIA 411
             +QG      GE    P  P  S   +        + L  R  P   PGP      EK A
Sbjct: 997  GAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAG----EKGA 1052

Query: 412  LNLEGCALSQGSLRTGTQ-EVGGQDP-GEAVQPCRQPLGARVADKVRKRRKVDEGA---- 465
               +G     G  R G Q  VG   P G A  P        + +  +K  K D+G     
Sbjct: 1053 PGEKGPQGPAG--RDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPP 1110

Query: 466  GDSAAVASGGAQTLALA-GSPAPSGHPKAGHSENGVEEDTEGRTGPK-----EGTPGSPS 519
            G        GA  +A   G P P G  + G      +E   G  GP      +G PG P 
Sbjct: 1111 GPPGLQGPVGAPGIAGGDGEPGPRG--QQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPG 1168

Query: 520  ETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGP-RPAGPAGDEPAESP 578
            E       GP G      P   PGPR  GP G   A+ P   PG     G  G++     
Sbjct: 1169 EKGENGDVGPMG------PPGPPGPR--GPQGPNGADGPQGPPGSVGSVGGVGEKGEPGE 1220

Query: 579  SETPGP-------SPAGPTRDEPAESPSETPGPRPA-GPAGDE-PAESPSETPGPRPAGP 629
            +  PGP        P G   ++    P    GP  A GP GD+ P  +P     P   GP
Sbjct: 1221 AGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGP 1280

Query: 630  AGDEPAESPSETPG-----------PSPAGPTRD-----EPAKAGE--AAELQDAEVESS 671
             G EP  +  +  G           P P GP+ +      P K G   AA  +  + E  
Sbjct: 1281 PG-EPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKG 1339

Query: 672  AK 673
            AK
Sbjct: 1340 AK 1341



 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 98/359 (27%), Positives = 120/359 (33%), Gaps = 77/359 (21%)

Query: 359  ERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQS-ASEVEKIAL-NLEG 416
            +R +  + G  GED PE   PK           R  P  +PGP   A E  K+ +  L G
Sbjct: 758  DRGEVGQIGPRGEDGPE--GPKG----------RAGPTGDPGPSGQAGEKGKLGVPGLPG 805

Query: 417  CALSQGSLRT----GTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVA 472
                QG   +    G     G+     V     P G R     R  R      G      
Sbjct: 806  YPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKG 865

Query: 473  SGGAQTLALAGSPAPSGH--PKAGHSENGVEEDTEGRTGP--KEGTPGSPSET------- 521
            + G       G P P G   P+      G     +G  GP  K+G PG P +        
Sbjct: 866  TSGGD-----GPPGPPGERGPQGPQGPVGFP-GPKGPPGPPGKDGLPGHPGQRGETGFQG 919

Query: 522  ----PGPS----PAGPAGDEPAESPSETPGPRPAGPAGDEPA------ESPSETPGPRPA 567
                PGP     P GP G+         PGP   GP G++        E     PGP+  
Sbjct: 920  KTGPPGPGGVVGPQGPTGETGPIGERGHPGP--PGPPGEQGLPGAAGKEGAKGDPGPQGI 977

Query: 568  ----GPAGDE--PAE--------SPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDE 613
                GPAG    P E        +P    G  P GP    P  SP E      AGP G  
Sbjct: 978  SGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPG--PVGSPGERGSAGTAGPIGLP 1035

Query: 614  PAESPSETPGPR----------PAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAE 662
                P   PGP           P GPAG +  + P   PGP+    +  E    GE  E
Sbjct: 1036 GRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGE 1094



 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 113/424 (26%), Positives = 145/424 (34%), Gaps = 65/424 (15%)

Query: 288 PQDKLRRFK--PSSLPHPL--EGSRKVEEEGSPGDPDHEASTQGR-----TCGPEHSKGG 338
           P DK  R +  P   P P   +G R  + E  P     EA  +G      T G     G 
Sbjct: 570 PGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGM 629

Query: 339 GRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGEDRPE-PLSPK-----ESKKRKLELSRR 392
             VD  P P+        P    Q    G  G   P+ P+ P      + K     L   
Sbjct: 630 AGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGA 689

Query: 393 EQPPTEPGPQSASEVEKIALNLEGCALSQGSLR-TGTQEVGGQDPGEAVQPCRQPLGARV 451
           + PP  PG +  S  EK AL   G    QG +   G + V G D    ++  +   G   
Sbjct: 690 DGPPGHPGKEGQSG-EKGALGPPG---PQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDG 745

Query: 452 ADKVRKRRKVDEGAGDSAAVASGGAQ-------TLALAGSPAPSGHPKAGHSEN-GVE-- 501
               +    +    G+   +   G              G P PSG  +AG     GV   
Sbjct: 746 FPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSG--QAGEKGKLGVPGL 803

Query: 502 EDTEGRTGPKEGT--PGSPSET-----------PGP----SPAGPAGDEPAESPSETPGP 544
               GR GPK  T  PG P              PGP     P GP G   A  P+  PGP
Sbjct: 804 PGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGP 863

Query: 545 RPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG----PSPAGPTRDEPAESPSE 600
           +     GD P   P E     P GP G    + P   PG    P   G   +   +  + 
Sbjct: 864 KGTS-GGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTG 922

Query: 601 TPGP----RPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG----PSPAGPT-R 651
            PGP     P GP G+         PG  P GP G++     +   G    P P G + +
Sbjct: 923 PPGPGGVVGPQGPTGETGPIGERGHPG--PPGPPGEQGLPGAAGKEGAKGDPGPQGISGK 980

Query: 652 DEPA 655
           D PA
Sbjct: 981 DGPA 984



 Score = 66.6 bits (161), Expect = 7e-11
 Identities = 100/367 (27%), Positives = 128/367 (34%), Gaps = 56/367 (15%)

Query: 314  GSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGEDR 373
            GSPG+ D +    G   G + SKG    +  P P  ++     P        AGG GE  
Sbjct: 1081 GSPGE-DGDKGEIGEP-GQKGSKGDKGENGPPGPPGLQGPVGAP------GIAGGDGE-- 1130

Query: 374  PEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGG 433
            P P   +    +K +   R  P   PGP          + L+G     G  +    +VG 
Sbjct: 1131 PGPRGQQGMFGQKGDEGARGFPGP-PGP----------IGLQGLPGPPGE-KGENGDVGP 1178

Query: 434  QDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGH--- 490
              P     P R P G   AD  +         G    V   G      AG+P P G    
Sbjct: 1179 MGPPGPPGP-RGPQGPNGADGPQGP---PGSVGSVGGVGEKGEP--GEAGNPGPPGEAGV 1232

Query: 491  --PKAGHSENGVEEDTEGRTGPK--EGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRP 546
              PK    E G E    G  GP   +G PG       P P G  GD     P     P P
Sbjct: 1233 GGPKGERGEKG-EAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGD-----PGPPGEPGP 1286

Query: 547  AGPAGDEPAESPSETPG-PRPAGPAGDEPAESPSETPGPSPAGPTRDEPAE--SPSETPG 603
            AG  G    +     PG P P GP+G+     P    GP  A        E  +  E   
Sbjct: 1287 AGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGA 1346

Query: 604  PRPAGPAGDEPAESPSETPGPRP----AGPAGDE--PAESPSETPGPSPAGP-----TRD 652
              P G  G    + P+  PGP       GP G++  P  +  + P P P GP      + 
Sbjct: 1347 EGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGP-PGPMGPPGLPGLKG 1405

Query: 653  EPAKAGE 659
            +P   GE
Sbjct: 1406 DPGSKGE 1412



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 61/211 (28%), Positives = 77/211 (36%), Gaps = 28/211 (13%)

Query: 479 LALAGSPAPSGHPKA----GHSENGVEEDTEGRTGP--------KEGTPGSPSETPGPSP 526
           + L G P P G P +    G S +   +   G  GP        K G PG+      P  
Sbjct: 495 MGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGE 554

Query: 527 AGPAGDEPAESPSETPGPR----------PAGPAGDEPAESPSETPGPRPA-GPAGDEPA 575
            G  GD   +     PG +          P GP GD+         GPR   G AG    
Sbjct: 555 PGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGL 614

Query: 576 ESPSETPG-PSPAGPTRDEPAESPSETPGPR-PAGPAGDEPAESPSETPGPR-PAGPAGD 632
             P  TPG P   G    +    P    GP+   GP G +    P   PGP+ P GP G+
Sbjct: 615 LGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGE 674

Query: 633 E-PAESPSETPGPSPAGPTRDEPAKAGEAAE 662
           + P   P     P   GP    P K G++ E
Sbjct: 675 KGPQGKPGLAGLPGADGPP-GHPGKEGQSGE 704



 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 114/439 (25%), Positives = 145/439 (33%), Gaps = 105/439 (23%)

Query: 312  EEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGE 371
            E G PG P  +        GP  + G    D  P PR  +          +GDE      
Sbjct: 1106 ENGPPGPPGLQ--------GPVGAPGIAGGDGEPGPRGQQGMFG-----QKGDEGARGFP 1152

Query: 372  DRPEPLS------PKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLR 425
              P P+       P   K    ++     PP  PGP+        A   +G   S GS+ 
Sbjct: 1153 GPPGPIGLQGLPGPPGEKGENGDVGPMG-PPGPPGPRGPQGPNG-ADGPQGPPGSVGSVG 1210

Query: 426  TGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQ-------- 477
             G  E G  +PGEA  P   P G       +  R     AG   A    GA+        
Sbjct: 1211 -GVGEKG--EPGEAGNP--GPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGP 1265

Query: 478  -----TLALAGSPAPSGHPKAGHSENGV-----EEDTEGRTGP-----KEGTPGSPSETP 522
                  +   G P P G P     ++GV     E+   G+ GP     + G PG P +  
Sbjct: 1266 KGNPGPVGFPGDPGPPGEPGPA-GQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRG 1324

Query: 523  GPSPAGPAG---------DEPAESPSETPGP-RPAGPAGDEPAESPSETPGP-------- 564
             P  AG  G         +  AE P    GP  P GPAG    E     PGP        
Sbjct: 1325 PPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPG 1384

Query: 565  --------RPAGPAG------DEPAESPSETPG-------PSPAGPTRDEPAESPSETPG 603
                     P GP G      D  ++     PG       P   G   D        +PG
Sbjct: 1385 AAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPG 1444

Query: 604  -------PRPAGPAGDEPAESPSETPG-PRPAGPAGDEPAESPSETPGPSPAGPTRDEPA 655
                   P PAGP G      P   PG P P GP G++ +  P+   G S        P 
Sbjct: 1445 AKGDGGIPGPAGPLG------PPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1498

Query: 656  KAGEAAELQDAEVESSAKS 674
              GE   +Q   + SS K+
Sbjct: 1499 PPGEV--IQPLPILSSKKT 1515



 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 95/365 (26%), Positives = 121/365 (33%), Gaps = 81/365 (22%)

Query: 287  GPQDKLRRFKPSSLPHPLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQ 346
            GPQ       P   P  +     V E+G PG+  +         GP    G G    GP+
Sbjct: 1189 GPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNP--------GPPGEAGVG----GPK 1236

Query: 347  PRSVEPQDAGPLERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASE 406
                E  +AGP        AG  G   P      +     +       PP EPGP     
Sbjct: 1237 GERGEKGEAGP-----PGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQ-- 1289

Query: 407  VEKIALNLEGCALSQGSLRTGTQEVGGQDPGEAVQPC----RQPLGARVADKVRKRRKVD 462
                    +G    +G      Q       GEA  P     R P GA  A+     R+ +
Sbjct: 1290 --------DGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEG----RQGE 1337

Query: 463  EGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGP--KEGTPGSPSE 520
            +GA   A  A G        G   P+G P          E   G  GP  ++G PG+  +
Sbjct: 1338 KGAKGEAG-AEGPPGKTGPVGPQGPAGKPGP--------EGLRGIPGPVGEQGLPGAAGQ 1388

Query: 521  TPGPSPAGPAG------DEPAESPSETPG-------PRPAGPAGDEPAESPSETPG---- 563
               P P GP G      D  ++     PG       P   G  GD        +PG    
Sbjct: 1389 DGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGD 1448

Query: 564  ---PRPAGPAGDEPAESPSETPG-PSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPS 619
               P PAGP G      P   PG P P GP  ++ +  P        AG  GD     P 
Sbjct: 1449 GGIPGPAGPLG------PPGPPGLPGPQGPKGNKGSTGP--------AGQKGDSGLPGPP 1494

Query: 620  ETPGP 624
             +PGP
Sbjct: 1495 GSPGP 1499



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 52/184 (28%), Positives = 62/184 (33%), Gaps = 49/184 (26%)

Query: 513 GTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG--------- 563
           G PG    T  P P G  G   A+  S  PGP+  GP G +    P+  PG         
Sbjct: 490 GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQ--GPRGVQGPPGPTGKPGKRGRPGADG 547

Query: 564 ----PRPAGPAGDEPAESPSETPG----------PSPAGPTRDE--------------PA 595
               P   G  GD   +     PG            P GP  D+              P 
Sbjct: 548 GRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPG 607

Query: 596 ES-------PSETPG-PRPAGPAGDEPAESPSETPGPR-PAGPAGDEPAESPSETPGP-S 645
           E+       P  TPG P   G AG +    P    GP+   GP G +    P   PGP  
Sbjct: 608 EAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQG 667

Query: 646 PAGP 649
           P GP
Sbjct: 668 PIGP 671



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 56/192 (29%), Positives = 68/192 (35%), Gaps = 31/192 (16%)

Query: 483 GSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETP 542
           G PA +   +   + +G   +   +  P    PG   E P P PAGPAG      P    
Sbjct: 365 GVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGP-PGPAGPAG---IMGPPGLQ 420

Query: 543 GPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAES---PSETPGPSPAGPTRD-EPAESP 598
           GP   GP GD     P   PG   A      P      P    G    GPT   + A++ 
Sbjct: 421 GP--TGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQ 478

Query: 599 SETPGPR-----PAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGP-------SP 646
           +     R     P GP G         T  P P G  G   A+  S  PGP        P
Sbjct: 479 AILQQARIALRGPPGPMG--------LTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGP 530

Query: 647 AGPTRDEPAKAG 658
            GPT  +P K G
Sbjct: 531 PGPT-GKPGKRG 541


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score = 79.7 bits (195), Expect = 8e-15
 Identities = 112/381 (29%), Positives = 139/381 (36%), Gaps = 63/381 (16%)

Query: 297  PSSLPHPLEGSRKVEEEGSPGDPDHEAST--QGRTCGPEHSKGGGRVDEGPQPRSVEPQD 354
            P   P P        ++G PG P     T  QG+T  P    G G V  GPQ  + E   
Sbjct: 926  PVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPP----GPGGV-VGPQGPTGE--- 977

Query: 355  AGPL-ERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALN 413
             GP+ ER      G  GE      + KE  K             +PGPQ  S  +  A  
Sbjct: 978  TGPIGERGHPGPPGPPGEQGLPGAAGKEGAKG------------DPGPQGISGKDGPA-G 1024

Query: 414  LEGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVAS 473
            L G    +G    G Q   G   GE  Q    P+G+              G   SA    
Sbjct: 1025 LRGFPGERGL--PGAQGAPGLKGGEGPQGPPGPVGS-------------PGERGSA---- 1065

Query: 474  GGAQTLALAGSPAPSGHP-KAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPS-PAGPAG 531
            G A  + L G P P G P  AG      E+  +G  G ++G  G P   PGP+ PAG  G
Sbjct: 1066 GTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAG-RDGVQG-PVGLPGPAGPAGSPG 1123

Query: 532  DEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGP----SPA 587
            ++  +     PG +  G  GD+    P   PG +  GP G          PGP       
Sbjct: 1124 EDGDKGEIGEPGQK--GSKGDKGENGPPGPPGLQ--GPVGAPGIAGGDGEPGPRGQQGMF 1179

Query: 588  GPTRDEPAESPSETPG-------PRPAGPAGDEPAESPSETPG-PRPAGPAGDEPAESPS 639
            G   DE A      PG       P P G  G+     P   PG P P GP G   A+ P 
Sbjct: 1180 GQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQ 1239

Query: 640  ETPGPSPAGPTRDEPAKAGEA 660
              PG   +     E  + GEA
Sbjct: 1240 GPPGSVGSVGGVGEKGEPGEA 1260



 Score = 69.7 bits (169), Expect = 8e-12
 Identities = 121/422 (28%), Positives = 150/422 (35%), Gaps = 80/422 (18%)

Query: 310  VEEEGSPGDPDHEASTQGR--TCGPEHSKGGGRVDEGPQPRSVEPQDAG----PLER--- 360
            + E G PG P      QG     G E +KG    D GPQ  S +   AG    P ER   
Sbjct: 981  IGERGHPGPPGPPGE-QGLPGAAGKEGAKG----DPGPQGISGKDGPAGLRGFPGERGLP 1035

Query: 361  -SQGDEAGGHGEDRPEPLSPKESKKRK--------LELSRREQPPTEPGPQSASEVEKIA 411
             +QG      GE    P  P  S   +        + L  R  P   PGP      EK A
Sbjct: 1036 GAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAG----EKGA 1091

Query: 412  LNLEGCALSQGSLRTGTQ-EVGGQDP-GEAVQPCRQPLGARVADKVRKRRKVDEGA---- 465
               +G     G  R G Q  VG   P G A  P        + +  +K  K D+G     
Sbjct: 1092 PGEKGPQGPAG--RDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPP 1149

Query: 466  GDSAAVASGGAQTLALA-GSPAPSGHPKAGHSENGVEEDTEGRTGPK-----EGTPGSPS 519
            G        GA  +A   G P P G  + G      +E   G  GP      +G PG P 
Sbjct: 1150 GPPGLQGPVGAPGIAGGDGEPGPRG--QQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPG 1207

Query: 520  ETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGP-RPAGPAGDEPAESP 578
            E       GP G      P   PGPR  GP G   A+ P   PG     G  G++     
Sbjct: 1208 EKGENGDVGPMG------PPGPPGPR--GPQGPNGADGPQGPPGSVGSVGGVGEKGEPGE 1259

Query: 579  SETPGP-------SPAGPTRDEPAESPSETPGPRPA-GPAGDE-PAESPSETPGPRPAGP 629
            +  PGP        P G   ++    P    GP  A GP GD+ P  +P     P   GP
Sbjct: 1260 AGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGP 1319

Query: 630  AGDEPAESPSETPG-----------PSPAGPTRD-----EPAKAGE--AAELQDAEVESS 671
             G EP  +  +  G           P P GP+ +      P K G   AA  +  + E  
Sbjct: 1320 PG-EPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKG 1378

Query: 672  AK 673
            AK
Sbjct: 1379 AK 1380



 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 98/359 (27%), Positives = 120/359 (33%), Gaps = 77/359 (21%)

Query: 359  ERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQS-ASEVEKIAL-NLEG 416
            +R +  + G  GED PE   PK           R  P  +PGP   A E  K+ +  L G
Sbjct: 797  DRGEVGQIGPRGEDGPE--GPKG----------RAGPTGDPGPSGQAGEKGKLGVPGLPG 844

Query: 417  CALSQGSLRT----GTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVA 472
                QG   +    G     G+     V     P G R     R  R      G      
Sbjct: 845  YPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKG 904

Query: 473  SGGAQTLALAGSPAPSGH--PKAGHSENGVEEDTEGRTGP--KEGTPGSPSET------- 521
            + G       G P P G   P+      G     +G  GP  K+G PG P +        
Sbjct: 905  TSGGD-----GPPGPPGERGPQGPQGPVGFP-GPKGPPGPPGKDGLPGHPGQRGETGFQG 958

Query: 522  ----PGPS----PAGPAGDEPAESPSETPGPRPAGPAGDEPA------ESPSETPGPRPA 567
                PGP     P GP G+         PGP   GP G++        E     PGP+  
Sbjct: 959  KTGPPGPGGVVGPQGPTGETGPIGERGHPGP--PGPPGEQGLPGAAGKEGAKGDPGPQGI 1016

Query: 568  ----GPAGDE--PAE--------SPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDE 613
                GPAG    P E        +P    G  P GP    P  SP E      AGP G  
Sbjct: 1017 SGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPG--PVGSPGERGSAGTAGPIGLP 1074

Query: 614  PAESPSETPGPR----------PAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAE 662
                P   PGP           P GPAG +  + P   PGP+    +  E    GE  E
Sbjct: 1075 GRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGE 1133



 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 113/424 (26%), Positives = 145/424 (34%), Gaps = 65/424 (15%)

Query: 288  PQDKLRRFK--PSSLPHPL--EGSRKVEEEGSPGDPDHEASTQGR-----TCGPEHSKGG 338
            P DK  R +  P   P P   +G R  + E  P     EA  +G      T G     G 
Sbjct: 609  PGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGM 668

Query: 339  GRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGEDRPE-PLSPK-----ESKKRKLELSRR 392
              VD  P P+        P    Q    G  G   P+ P+ P      + K     L   
Sbjct: 669  AGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGA 728

Query: 393  EQPPTEPGPQSASEVEKIALNLEGCALSQGSLR-TGTQEVGGQDPGEAVQPCRQPLGARV 451
            + PP  PG +  S  EK AL   G    QG +   G + V G D    ++  +   G   
Sbjct: 729  DGPPGHPGKEGQSG-EKGALGPPG---PQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDG 784

Query: 452  ADKVRKRRKVDEGAGDSAAVASGGAQ-------TLALAGSPAPSGHPKAGHSEN-GVE-- 501
                +    +    G+   +   G              G P PSG  +AG     GV   
Sbjct: 785  FPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSG--QAGEKGKLGVPGL 842

Query: 502  EDTEGRTGPKEGT--PGSPSET-----------PGP----SPAGPAGDEPAESPSETPGP 544
                GR GPK  T  PG P              PGP     P GP G   A  P+  PGP
Sbjct: 843  PGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGP 902

Query: 545  RPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG----PSPAGPTRDEPAESPSE 600
            +     GD P   P E     P GP G    + P   PG    P   G   +   +  + 
Sbjct: 903  KGTS-GGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTG 961

Query: 601  TPGP----RPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG----PSPAGPT-R 651
             PGP     P GP G+         PG  P GP G++     +   G    P P G + +
Sbjct: 962  PPGPGGVVGPQGPTGETGPIGERGHPG--PPGPPGEQGLPGAAGKEGAKGDPGPQGISGK 1019

Query: 652  DEPA 655
            D PA
Sbjct: 1020 DGPA 1023



 Score = 66.6 bits (161), Expect = 7e-11
 Identities = 100/367 (27%), Positives = 128/367 (34%), Gaps = 56/367 (15%)

Query: 314  GSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGEDR 373
            GSPG+ D +    G   G + SKG    +  P P  ++     P        AGG GE  
Sbjct: 1120 GSPGE-DGDKGEIGEP-GQKGSKGDKGENGPPGPPGLQGPVGAP------GIAGGDGE-- 1169

Query: 374  PEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGG 433
            P P   +    +K +   R  P   PGP          + L+G     G  +    +VG 
Sbjct: 1170 PGPRGQQGMFGQKGDEGARGFPGP-PGP----------IGLQGLPGPPGE-KGENGDVGP 1217

Query: 434  QDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGH--- 490
              P     P R P G   AD  +         G    V   G      AG+P P G    
Sbjct: 1218 MGPPGPPGP-RGPQGPNGADGPQGP---PGSVGSVGGVGEKGEP--GEAGNPGPPGEAGV 1271

Query: 491  --PKAGHSENGVEEDTEGRTGPK--EGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRP 546
              PK    E G E    G  GP   +G PG       P P G  GD     P     P P
Sbjct: 1272 GGPKGERGEKG-EAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGD-----PGPPGEPGP 1325

Query: 547  AGPAGDEPAESPSETPG-PRPAGPAGDEPAESPSETPGPSPAGPTRDEPAE--SPSETPG 603
            AG  G    +     PG P P GP+G+     P    GP  A        E  +  E   
Sbjct: 1326 AGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGA 1385

Query: 604  PRPAGPAGDEPAESPSETPGPRP----AGPAGDE--PAESPSETPGPSPAGP-----TRD 652
              P G  G    + P+  PGP       GP G++  P  +  + P P P GP      + 
Sbjct: 1386 EGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGP-PGPMGPPGLPGLKG 1444

Query: 653  EPAKAGE 659
            +P   GE
Sbjct: 1445 DPGSKGE 1451



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 61/211 (28%), Positives = 77/211 (36%), Gaps = 28/211 (13%)

Query: 479 LALAGSPAPSGHPKA----GHSENGVEEDTEGRTGP--------KEGTPGSPSETPGPSP 526
           + L G P P G P +    G S +   +   G  GP        K G PG+      P  
Sbjct: 534 MGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGE 593

Query: 527 AGPAGDEPAESPSETPGPR----------PAGPAGDEPAESPSETPGPRPA-GPAGDEPA 575
            G  GD   +     PG +          P GP GD+         GPR   G AG    
Sbjct: 594 PGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGL 653

Query: 576 ESPSETPG-PSPAGPTRDEPAESPSETPGPR-PAGPAGDEPAESPSETPGPR-PAGPAGD 632
             P  TPG P   G    +    P    GP+   GP G +    P   PGP+ P GP G+
Sbjct: 654 LGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGE 713

Query: 633 E-PAESPSETPGPSPAGPTRDEPAKAGEAAE 662
           + P   P     P   GP    P K G++ E
Sbjct: 714 KGPQGKPGLAGLPGADGPP-GHPGKEGQSGE 743



 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 114/439 (25%), Positives = 145/439 (33%), Gaps = 105/439 (23%)

Query: 312  EEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGE 371
            E G PG P  +        GP  + G    D  P PR  +          +GDE      
Sbjct: 1145 ENGPPGPPGLQ--------GPVGAPGIAGGDGEPGPRGQQGMFG-----QKGDEGARGFP 1191

Query: 372  DRPEPLS------PKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLR 425
              P P+       P   K    ++     PP  PGP+        A   +G   S GS+ 
Sbjct: 1192 GPPGPIGLQGLPGPPGEKGENGDVGPMG-PPGPPGPRGPQGPNG-ADGPQGPPGSVGSVG 1249

Query: 426  TGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQ-------- 477
             G  E G  +PGEA  P   P G       +  R     AG   A    GA+        
Sbjct: 1250 -GVGEKG--EPGEAGNP--GPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGP 1304

Query: 478  -----TLALAGSPAPSGHPKAGHSENGV-----EEDTEGRTGP-----KEGTPGSPSETP 522
                  +   G P P G P     ++GV     E+   G+ GP     + G PG P +  
Sbjct: 1305 KGNPGPVGFPGDPGPPGEPGPA-GQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRG 1363

Query: 523  GPSPAGPAG---------DEPAESPSETPGP-RPAGPAGDEPAESPSETPGP-------- 564
             P  AG  G         +  AE P    GP  P GPAG    E     PGP        
Sbjct: 1364 PPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPG 1423

Query: 565  --------RPAGPAG------DEPAESPSETPG-------PSPAGPTRDEPAESPSETPG 603
                     P GP G      D  ++     PG       P   G   D        +PG
Sbjct: 1424 AAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPG 1483

Query: 604  -------PRPAGPAGDEPAESPSETPG-PRPAGPAGDEPAESPSETPGPSPAGPTRDEPA 655
                   P PAGP G      P   PG P P GP G++ +  P+   G S        P 
Sbjct: 1484 AKGDGGIPGPAGPLG------PPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1537

Query: 656  KAGEAAELQDAEVESSAKS 674
              GE   +Q   + SS K+
Sbjct: 1538 PPGEV--IQPLPILSSKKT 1554



 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 95/365 (26%), Positives = 121/365 (33%), Gaps = 81/365 (22%)

Query: 287  GPQDKLRRFKPSSLPHPLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQ 346
            GPQ       P   P  +     V E+G PG+  +         GP    G G    GP+
Sbjct: 1228 GPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNP--------GPPGEAGVG----GPK 1275

Query: 347  PRSVEPQDAGPLERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASE 406
                E  +AGP        AG  G   P      +     +       PP EPGP     
Sbjct: 1276 GERGEKGEAGP-----PGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQ-- 1328

Query: 407  VEKIALNLEGCALSQGSLRTGTQEVGGQDPGEAVQPC----RQPLGARVADKVRKRRKVD 462
                    +G    +G      Q       GEA  P     R P GA  A+     R+ +
Sbjct: 1329 --------DGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEG----RQGE 1376

Query: 463  EGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGP--KEGTPGSPSE 520
            +GA   A  A G        G   P+G P          E   G  GP  ++G PG+  +
Sbjct: 1377 KGAKGEAG-AEGPPGKTGPVGPQGPAGKPGP--------EGLRGIPGPVGEQGLPGAAGQ 1427

Query: 521  TPGPSPAGPAG------DEPAESPSETPG-------PRPAGPAGDEPAESPSETPG---- 563
               P P GP G      D  ++     PG       P   G  GD        +PG    
Sbjct: 1428 DGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGD 1487

Query: 564  ---PRPAGPAGDEPAESPSETPG-PSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPS 619
               P PAGP G      P   PG P P GP  ++ +  P        AG  GD     P 
Sbjct: 1488 GGIPGPAGPLG------PPGPPGLPGPQGPKGNKGSTGP--------AGQKGDSGLPGPP 1533

Query: 620  ETPGP 624
             +PGP
Sbjct: 1534 GSPGP 1538



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 52/184 (28%), Positives = 62/184 (33%), Gaps = 49/184 (26%)

Query: 513 GTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG--------- 563
           G PG    T  P P G  G   A+  S  PGP+  GP G +    P+  PG         
Sbjct: 529 GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQ--GPRGVQGPPGPTGKPGKRGRPGADG 586

Query: 564 ----PRPAGPAGDEPAESPSETPG----------PSPAGPTRDE--------------PA 595
               P   G  GD   +     PG            P GP  D+              P 
Sbjct: 587 GRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPG 646

Query: 596 ES-------PSETPG-PRPAGPAGDEPAESPSETPGPR-PAGPAGDEPAESPSETPGP-S 645
           E+       P  TPG P   G AG +    P    GP+   GP G +    P   PGP  
Sbjct: 647 EAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQG 706

Query: 646 PAGP 649
           P GP
Sbjct: 707 PIGP 710



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 56/192 (29%), Positives = 68/192 (35%), Gaps = 31/192 (16%)

Query: 483 GSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETP 542
           G PA +   +   + +G   +   +  P    PG   E P P PAGPAG      P    
Sbjct: 404 GVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGP-PGPAGPAG---IMGPPGLQ 459

Query: 543 GPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAES---PSETPGPSPAGPTRD-EPAESP 598
           GP   GP GD     P   PG   A      P      P    G    GPT   + A++ 
Sbjct: 460 GP--TGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQ 517

Query: 599 SETPGPR-----PAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGP-------SP 646
           +     R     P GP G         T  P P G  G   A+  S  PGP        P
Sbjct: 518 AILQQARIALRGPPGPMG--------LTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGP 569

Query: 647 AGPTRDEPAKAG 658
            GPT  +P K G
Sbjct: 570 PGPT-GKPGKRG 580


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 79.7 bits (195), Expect = 8e-15
 Identities = 90/328 (27%), Positives = 119/328 (36%), Gaps = 45/328 (13%)

Query: 327 GRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGEDRPEPLSPKESKKRK 386
           G   GP  S  GG   +GP P   +PQ  GP  +      G     +P+   P+  K R 
Sbjct: 34  GNPQGP--SPQGGNKPQGPPPPPGKPQ--GPPPQGGNKPQGPPPPGKPQGPPPQGDKSR- 88

Query: 387 LELSRREQP--PTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGGQDPGEAVQPCR 444
              S R  P  P  P PQ  ++ +       G     G  + G    GG  P     P +
Sbjct: 89  ---SPRSPPGKPQGPPPQGGNQPQ-------GPPPPPGKPQ-GPPPQGGNRPQGPPPPGK 137

Query: 445 QPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDT 504
                   DK R  R              GG Q     G P P G P+    + G     
Sbjct: 138 PQGPPPQGDKSRSPRSPP--GKPQGPPPQGGNQP---QGPPPPPGKPQGPPPQGG----- 187

Query: 505 EGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGP 564
                 K   P  P +  GP P G         P +  GP P G  G++P + P   PG 
Sbjct: 188 -----KKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQG--GNQP-QGPPPPPG- 238

Query: 565 RPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPR-PAGPAGDEPAESPSETPG 623
           +P GP    P +  ++  GP P G  +  PA+  S++   R P G     P +  +   G
Sbjct: 239 KPQGP----PPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQG 294

Query: 624 PRPAGPAGDEPAESPSETPGPSPAGPTR 651
           P P  PAG  P + P   P   P GP R
Sbjct: 295 PPP--PAGGNP-QQPQAPPAGQPQGPPR 319



 Score = 77.0 bits (188), Expect = 5e-14
 Identities = 61/219 (27%), Positives = 83/219 (37%), Gaps = 24/219 (10%)

Query: 462 DEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSET 521
           D    +S ++ +G  Q  +  G   P G P       G  +    + G K   P  P + 
Sbjct: 22  DVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPP----GKPQGPPPQGGNKPQGPPPPGKP 77

Query: 522 PGPSPAGPAGDEPAESPSETPGPRPAG---PAGDEPAESPSETPGPRPAGPAGDEPAESP 578
            GP P G     P   P +  GP P G   P G  P   P +  GP P G    +    P
Sbjct: 78  QGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQG--PPPPPGKPQGPPPQGGNRPQGPPPP 135

Query: 579 SETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESP 638
            +  GP P G     P   P +  GP P G  G++P + P   PG +P GP    P +  
Sbjct: 136 GKPQGPPPQGDKSRSPRSPPGKPQGPPPQG--GNQP-QGPPPPPG-KPQGP----PPQGG 187

Query: 639 SETPGPSPAGPTRDEPAKAGEAAELQDAEVESSAKSGKP 677
            +  GP P G  +  P +        D    S +  GKP
Sbjct: 188 KKPQGPPPPGKPQGPPPQG-------DKSRSSQSPPGKP 219



 Score = 76.6 bits (187), Expect = 7e-14
 Identities = 60/215 (27%), Positives = 75/215 (34%), Gaps = 26/215 (12%)

Query: 485 PAPSGHPKAGHSENGVEEDTEGRTGPKEGTP---GSPSETPGPSPAGPAGDEP------- 534
           P P G P+    +           G  +G P   G+  + P P P  P G  P       
Sbjct: 71  PPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQ 130

Query: 535 -AESPSETPGPRPAGPAGDEPAESPSETPGPRPAG---PAGDEPAESPSETPGPSPAGPT 590
               P +  GP P G     P   P +  GP P G   P G  P   P +  GP P G  
Sbjct: 131 GPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQG--PPPPPGKPQGPPPQGGK 188

Query: 591 RDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAG---PAGDEPAESPSETPGPSPA 647
           + +    P +  GP P G         P +  GP P G   P G  P   P +  GP P 
Sbjct: 189 KPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQG--PPPPPGKPQGPPPQ 246

Query: 648 G---PTRDEPAKAGEAAELQDAEVESSAKS--GKP 677
           G   P    P    +    Q      SA+S  GKP
Sbjct: 247 GGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKP 281



 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 55/201 (27%), Positives = 72/201 (35%), Gaps = 20/201 (9%)

Query: 483 GSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETP 542
           G P P G P+    + G         GP    PG P    GP P G     P   P +  
Sbjct: 110 GPPPPPGKPQGPPPQGGNRPQ-----GPPP--PGKPQ---GPPPQGDKSRSPRSPPGKPQ 159

Query: 543 GPRPAG---PAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPS 599
           GP P G   P G  P   P +  GP P G    +    P +  GP P G         P 
Sbjct: 160 GPPPQGGNQPQGPPPP--PGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPG 217

Query: 600 ETPGPRPAG---PAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAK 656
           +  GP P G   P G  P   P +  GP P G    +    P +  GP   G ++ + A+
Sbjct: 218 KPQGPPPQGGNQPQGPPPP--PGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSAR 275

Query: 657 AGEAAELQDAEVESSAKSGKP 677
           +         + E +   G P
Sbjct: 276 SPPGKPQGPPQQEGNNPQGPP 296



 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 72/291 (24%), Positives = 98/291 (33%), Gaps = 36/291 (12%)

Query: 303 PLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKG--------GGRVDEGPQPRSVEPQD 354
           P +G  K +    PG P        ++  P    G        GG   +GP P   +PQ 
Sbjct: 61  PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 120

Query: 355 AGPL--ERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQP--PTEPGPQSASEVEKI 410
             P    R QG    G    +P+   P+  K R    S R  P  P  P PQ  ++ +  
Sbjct: 121 PPPQGGNRPQGPPPPG----KPQGPPPQGDKSR----SPRSPPGKPQGPPPQGGNQPQ-- 170

Query: 411 ALNLEGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAA 470
                G     G  + G    GG+ P     P +        DK R  +           
Sbjct: 171 -----GPPPPPGKPQ-GPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPP--GKPQGP 222

Query: 471 VASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTP---GSPSETPGPSPA 527
              GG Q     G P P G P+    + G +       G  +G P   GS S++    P 
Sbjct: 223 PPQGGNQP---QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPG 279

Query: 528 GPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESP 578
            P G    E  +    P PAG    +P   P+  P   P  P G  P+  P
Sbjct: 280 KPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 330


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score = 78.6 bits (192), Expect = 2e-14
 Identities = 115/389 (29%), Positives = 143/389 (36%), Gaps = 67/389 (17%)

Query: 300  LPHPLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLE 359
            LP P+        EG PG P    S   R  GP  + G   +   P P+   P  AG   
Sbjct: 1064 LPGPVGALGLKGNEGPPGPPGPAGSPGER--GPAGAAGPIGIPGRPGPQG-PPGPAG--- 1117

Query: 360  RSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCAL 419
                 E G  GE  P+  + ++  +  + L     P   PG       +K  +   G   
Sbjct: 1118 -----EKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDG----DKGEIGEPGQKG 1168

Query: 420  SQGSLRTGTQEVGGQDPGEAVQPCRQP--LGARVADKVRKRRKVDEGAGDSAAVASGGAQ 477
            S+G       E G   P     P  QP   GA      R ++ +    GD       G  
Sbjct: 1169 SKGD----KGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPP 1224

Query: 478  -TLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPG--SPSETPGPS-PAGPAGD- 532
              + L G P P G       E G   D  G+ GP  G PG   PS  PG   P GP G  
Sbjct: 1225 GPVGLQGLPGPPG-------EKGETGDV-GQMGPP-GPPGPRGPSGAPGADGPQGPPGGI 1275

Query: 533  ----------EPAES-----PSETPGPRPAGPAGDEPAESPSETPGPR-PAGPAGDE-PA 575
                      EP E+     P E   P P G  G++    PS   GP  P GP GD+ P 
Sbjct: 1276 GNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPK 1335

Query: 576  ESPSETPGPSPAGPTRDEPAESPSETPGPR-PAGPAGDEPAE-SPSETPGPRPAGPAGDE 633
             SP     P   GP    P E     PGP    GP GD+  +  P +T  P P G  G  
Sbjct: 1336 GSPGPVGFPGDPGP----PGE-----PGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPG-- 1384

Query: 634  PAESPSETPGPSPAGP--TRDEPAKAGEA 660
            P+  P +   P PAGP   + E    GEA
Sbjct: 1385 PSGPPGKRGPPGPAGPEGRQGEKGAKGEA 1413



 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 119/435 (27%), Positives = 148/435 (34%), Gaps = 73/435 (16%)

Query: 297  PSSLPHPLEGSRKVEEEGSPGDPDHEAST--QGRTCGPEHSKG-----GGRVDEGPQPRS 349
            P+  P P        ++G PG P     T  QG+T GP    G     G   + GP    
Sbjct: 956  PTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKT-GPPGPPGVVGPQGPTGETGPMGER 1014

Query: 350  VEPQDAGP-----------LERSQGDE--AGGHGEDRPEPLSPKESKKR------KLELS 390
              P   GP            E ++GD   AG  G+D P  L      +        L L 
Sbjct: 1015 GHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLK 1074

Query: 391  RREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGAR 450
              E PP  PGP + S  E+      G     G  R G Q   G    +     + P G  
Sbjct: 1075 GNEGPPGPPGP-AGSPGERGPAGAAGPIGIPG--RPGPQGPPGPAGEKGAPGEKGPQGPA 1131

Query: 451  VADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGP 510
              D ++    +   AG        G +     G P   G  K    E G      G TGP
Sbjct: 1132 GRDGLQGPVGLPGPAGPVGPPGEDGDK--GEIGEPGQKGS-KGDKGEQG----PPGPTGP 1184

Query: 511  KE--GTPGSPSETPGPSPAGPAG---DEPAESPSETPGPR-------------PAGPAGD 552
            +   G PG       P P G  G    +  E P   PGP                G  GD
Sbjct: 1185 QGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGD 1244

Query: 553  EPAESPSETPGPRPAGPAGDEPAESPSETPG----PSPAGPTRDEPAES-----PSETPG 603
                 P   PGPR  GP+G   A+ P   PG    P   G  + EP E+     P E   
Sbjct: 1245 VGQMGPPGPPGPR--GPSGAPGADGPQGPPGGIGNPGAVGE-KGEPGEAGEPGLPGEGGP 1301

Query: 604  PRPAGPAGDEPAESPSETPGPR-PAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAE 662
            P P G  G++    PS   GP  P GP GD+    P  +PGP         P + G A  
Sbjct: 1302 PGPKGERGEKGESGPSGAAGPPGPKGPPGDD---GPKGSPGPVGFPGDPGPPGEPGPAG- 1357

Query: 663  LQDAEVESSAKSGKP 677
             QD         G+P
Sbjct: 1358 -QDGPPGDKGDDGEP 1371



 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 102/361 (28%), Positives = 127/361 (35%), Gaps = 59/361 (16%)

Query: 338  GGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPT 397
            G R + GP     E    GP  R      GG   D P PL P   +K KL +      P 
Sbjct: 826  GDRGEIGPPGPRGEDGPEGPKGR------GGPNGD-PGPLGPP-GEKGKLGVPGLPGYPG 877

Query: 398  EPGPQSASEVEKIALNLEGCALSQGSLRT-GTQEVGGQDPGEAVQPCRQPLGARVADKVR 456
              GP+ +           G    +G   T G     GQ      +  R P G       +
Sbjct: 878  RQGPKGSIGFP----GFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPK 933

Query: 457  KRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKA-------GHSENGVEEDTEGRTG 509
                 D  AG        G Q     G P P G P         GH     E   +G+TG
Sbjct: 934  GNSGGDGPAGPPGERGPNGPQ--GPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTG 991

Query: 510  PKEGTPGSPSETPGPSPAGPAGDEPAESPSETPG----PRPAGPAGDEPAESPSETPG-- 563
            P  G PG           GP G+     P   PG    P  AG  G +    P+  PG  
Sbjct: 992  PP-GPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKD 1050

Query: 564  --------------PRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSET-----PGP 604
                          P P G  G +  E P   PGP+   P    PA +         PGP
Sbjct: 1051 GPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPA-GSPGERGPAGAAGPIGIPGRPGP 1109

Query: 605  R-PAGPAGDEPAESPSETPGPR-PAGPAGDEPAESPSETPGPS-PAGPTRDEPAKAGEAA 661
            + P GPAG++ A      PG + P GPAG +  + P   PGP+ P GP  ++  K GE  
Sbjct: 1110 QGPPGPAGEKGA------PGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDK-GEIG 1162

Query: 662  E 662
            E
Sbjct: 1163 E 1163



 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 103/369 (27%), Positives = 129/369 (34%), Gaps = 45/369 (12%)

Query: 313  EGSPGDPDHEASTQGRTCGPEHSKG--GGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHG 370
            +G PG P      QG   GP   +G  G +   GPQ     P + GPL +      G  G
Sbjct: 702  DGQPG-PKGNVGPQGEP-GPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKP--GLPGMPG 757

Query: 371  EDRPEPLSPKES---KKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLR-- 425
             D P     KE    +K        + P   PGP+     + I   L+G    +G     
Sbjct: 758  ADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIR-GLKGTKGEKGEDGFP 816

Query: 426  --TGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQ-TLALA 482
               G   + G D GE   P     G R  D     +      GD   +   G +  L + 
Sbjct: 817  GFKGDMGIKG-DRGEIGPP-----GPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVP 870

Query: 483  GSPAPSGH--PKAGHSENGVEEDTEGRTGPK--EGTPGSPSETPGPSPAGPAGDEPAESP 538
            G P   G   PK      G      G  G K   GTPG P       P GP G+      
Sbjct: 871  GLPGYPGRQGPKGSIGFPGFP----GANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGI 926

Query: 539  SETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG-------PSPAGPTR 591
            +  PGP+     GD PA  P E     P GP G    + P   PG       P   G T 
Sbjct: 927  TGKPGPK-GNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETG 985

Query: 592  DEPAESPSETPG-PRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG----PSP 646
             +    P   PG   P GP G+         PG  P GP G++     +   G    P P
Sbjct: 986  FQGKTGPPGPPGVVGPQGPTGETGPMGERGHPG--PPGPPGEQGLPGLAGKEGTKGDPGP 1043

Query: 647  AG-PTRDEP 654
            AG P +D P
Sbjct: 1044 AGLPGKDGP 1052



 Score = 66.2 bits (160), Expect = 9e-11
 Identities = 63/218 (28%), Positives = 79/218 (36%), Gaps = 32/218 (14%)

Query: 474 GGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPK--EGTPGSPSETPG-------- 523
           G A  + L G P P G P +G  +   E    G  GP+  +G PG P+  PG        
Sbjct: 559 GPAGPMGLTGRPGPVGPPGSGGLKG--EPGDVGPQGPRGVQGPPG-PAGKPGRRGRAGSD 615

Query: 524 -----PSPAGPAGDEPAESPSETPGPR----------PAGPAGDEPAESPSETPGPRP-A 567
                P   GP GD   +  +  PG +          P GP GD+         GPR   
Sbjct: 616 GARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLP 675

Query: 568 GPAGDEPAESPSETPG-PSPAGPTRDEPAESPSETPGPR-PAGPAGDEPAESPSETPGPR 625
           G  G      P   PG P P G T  +    P    GP+   GP G +        PGP+
Sbjct: 676 GEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQ 735

Query: 626 PA-GPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAE 662
            A GP G++        PG   A      P K G   E
Sbjct: 736 GAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGE 773



 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 106/438 (24%), Positives = 143/438 (32%), Gaps = 97/438 (22%)

Query: 312  EEGSPGDPDHEASTQGRTC--GPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGH 369
            ++GS GD   E    G T   GP    G    D  P PR  +      L   +GDE    
Sbjct: 1166 QKGSKGDKG-EQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQG-----LFGQKGDEGPRG 1219

Query: 370  GEDRPEPLS------PKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGS 423
                P P+       P   K    ++ +   PP  PGP+  S     A   +G     G 
Sbjct: 1220 FPGPPGPVGLQGLPGPPGEKGETGDVGQMG-PPGPPGPRGPSG----APGADGPQGPPGG 1274

Query: 424  LRTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVAS---------- 473
            +          +PGEA +P     G     K  +  K + G   +A              
Sbjct: 1275 IGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGP 1334

Query: 474  -GGAQTLALAGSPAPSGHP-KAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPS------ 525
             G    +   G P P G P  AG      ++  +G  G + G+PG P+  PGPS      
Sbjct: 1335 KGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPG-QTGSPG-PTGEPGPSGPPGKR 1392

Query: 526  -PAGPAGDEPAESPSETPG-------PRPAGPAGDEPAESPSETPG----PRPAGPAGDE 573
             P GPAG E  +      G       P   GP G + A       G    P P G  G  
Sbjct: 1393 GPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLP 1452

Query: 574  PAESPSETPGPSPA-------------------------GPTRDEPAESPSETPGPR-PA 607
             +  P   PGP                            GP  ++  +     PGP+  +
Sbjct: 1453 GSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSS 1512

Query: 608  GPAGDEPAESPSET------------PGPR-------PAGPAGDEPAESPSETPGPSPAG 648
            GP G++    PS              PGP+       P GP G+     P   PGP P  
Sbjct: 1513 GPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGP-PGE 1571

Query: 649  PTRDEPAKAGEAAELQDA 666
              +  P +A       DA
Sbjct: 1572 VIQPLPIQASRTRRNIDA 1589



 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 89/326 (27%), Positives = 110/326 (33%), Gaps = 56/326 (17%)

Query: 313 EGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGE- 371
           +G PG P        R  G     GG    +GP   + E Q    L++++    G  G  
Sbjct: 510 DGLPGPPGTMLMLPFRFGG-----GGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPM 564

Query: 372 ---DRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGT 428
               RP P+ P  S   K E       P + GPQ                        G 
Sbjct: 565 GLTGRPGPVGPPGSGGLKGE-------PGDVGPQ------------------------GP 593

Query: 429 QEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQ-TLALAGSPAP 487
           + V G  PG A +P R+  G   +D  R         GD       G        G P P
Sbjct: 594 RGVQGP-PGPAGKPGRR--GRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGP 650

Query: 488 SGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETP--GP-SPAGPAGDEPAESPSETPGP 544
           SG P  G   +  E   +G  GP+ G PG P      GP  P GP G          PGP
Sbjct: 651 SGPP--GPPGDDGERGDDGEVGPR-GLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGP 707

Query: 545 R-PAGPAGDEPAESPSETPG----PRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPS 599
           +   GP G+         PG    P P G  G    + P   PG  P  P  D P   P 
Sbjct: 708 KGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPG-LPGMPGADGPPGHPG 766

Query: 600 ETPGPRPAGPAGDEPAESPSETPGPR 625
           +   P   G  G    + P   PGPR
Sbjct: 767 KEGPPGEKGGQGPPGPQGPIGYPGPR 792



 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 54/204 (26%), Positives = 68/204 (33%), Gaps = 37/204 (18%)

Query: 483 GSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETP 542
           G  A S  P     E+  +   +       G  G    T  P P GP G    +      
Sbjct: 529 GGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDV 588

Query: 543 GPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETP 602
           GP+  GP G +    P+  PG R  G AG + A        P   GP  D   +  +  P
Sbjct: 589 GPQ--GPRGVQGPPGPAGKPGRR--GRAGSDGARGM-----PGQTGPKGDRGFDGLAGLP 639

Query: 603 GPR----------PAGPAGDE----------PAESPSETPGPR-------PAGPAGDEPA 635
           G +          P GP GD+          P   P E PGPR       P GP G    
Sbjct: 640 GEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGE-PGPRGLLGPKGPPGPPGPPGV 698

Query: 636 ESPSETPGPSPAGPTRDEPAKAGE 659
                 PGP      + EP   G+
Sbjct: 699 TGMDGQPGPKGNVGPQGEPGPPGQ 722



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 59/217 (27%), Positives = 73/217 (33%), Gaps = 50/217 (23%)

Query: 505 EGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPG-------PRPAGP-------- 549
           EG  GP EG  G P       P G  GD     P   PG       P P G         
Sbjct: 468 EGPPGP-EGPAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRF 526

Query: 550 --AGDEPAESPSETPGPRPA------------GPAGDEPAESPSETPGPSPAGPTRDEPA 595
              GD  ++ P  +     A            GPAG           GP  +G  + EP 
Sbjct: 527 GGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPG 586

Query: 596 ESPSETPGPR----PAGPAGDEPAESPSETPG----PRPAGPAGDEPAESPSETPG---- 643
           +   +  GPR    P GPAG       + + G    P   GP GD   +  +  PG    
Sbjct: 587 DVGPQ--GPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGH 644

Query: 644 ---PSPAGPTRDEPAKAGEAAELQDAEVESSAKSGKP 677
              P P+GP    P   GE  +  D EV      G+P
Sbjct: 645 RGDPGPSGPP-GPPGDDGERGD--DGEVGPRGLPGEP 678



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 54/215 (25%), Positives = 67/215 (31%), Gaps = 25/215 (11%)

Query: 460 KVDEGAGDSAAVASGGAQTLALAG--SPAPSGHPKAGHSENGVEEDTEGRTG---PKEGT 514
           +  EGAG    V  G    +      +P+P      G  E   ++ T+   G   P    
Sbjct: 322 ETSEGAGKEEDVGIGDYDYVPSEDYYTPSPYDDLTYGEGEENPDQPTDPGAGAEIPTSTA 381

Query: 515 PGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEP 574
             S S  P P P   A D   E   ET          DE    P   P   P+      P
Sbjct: 382 DTSNSSNPAPPPGEGADDLEGEFTEETIRNL------DENYYDPYYDPTSSPSEIGPGMP 435

Query: 575 AESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGP----RPAGPA 630
           A   +   G       + +  E     PG    GP G    E P+  PGP     P G  
Sbjct: 436 ANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPG---PEGPAGLPGPPGTMGPTGQV 492

Query: 631 GDEPAESPSETPG-------PSPAGPTRDEPAKAG 658
           GD     P   PG       P P G     P + G
Sbjct: 493 GDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFG 527



 Score = 31.6 bits (70), Expect = 2.5
 Identities = 39/154 (25%), Positives = 50/154 (32%), Gaps = 5/154 (3%)

Query: 490 HPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGP 549
           +P   ++E   E +T     P    P    + P PS       E A+  +E P      P
Sbjct: 258 NPDEYYTEGDGEGETYYYEYPYYEDPEDLGKEPTPSKKPV---EAAKETTEVPEELTPTP 314

Query: 550 AGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGP-TRDEPAESPSETPGPRPAG 608
               P    SE  G       GD       +   PSP    T  E  E+P +   P    
Sbjct: 315 TEAAPMPETSEGAGKEEDVGIGDYDYVPSEDYYTPSPYDDLTYGEGEENPDQPTDPGAGA 374

Query: 609 PAGDEPAE-SPSETPGPRPAGPAGDEPAESPSET 641
                 A+ S S  P P P   A D   E   ET
Sbjct: 375 EIPTSTADTSNSSNPAPPPGEGADDLEGEFTEET 408


>gi|239745501 PREDICTED: similar to acyl-CoA synthetase medium-chain
           family member 2 [Homo sapiens]
          Length = 1122

 Score = 78.6 bits (192), Expect = 2e-14
 Identities = 64/186 (34%), Positives = 94/186 (50%), Gaps = 22/186 (11%)

Query: 487 PSGHPKAGHSENGVEEDTEGRTGPKEG----TPGSPSETPGPSPAGPAGDEPAESPSE-T 541
           PS  P A  +     E   G   P       TP     TP P  A P+ D+  ++P+E  
Sbjct: 360 PSAPPSADDNIKTTAERLRGPLPPSADDNLKTPSERQLTPLPPSAPPSADDNIKTPAEHL 419

Query: 542 PGPRPAGPAGDEPAESPSE---TPGPRPAGPAGDEPAESPSE-TPGPSPAGPTRDEPAES 597
            GP P  P+ D+  ++PSE   TP P  A P+ D+  ++P+E   GP P  P+ D+  ++
Sbjct: 420 RGPLP--PSADDNLKTPSERQLTPLPPSAPPSADDNIKTPAERLRGPLP--PSADDNLKT 475

Query: 598 PSE---TPGPRPAGPAGDEPAESPSE-TPGPRPAGPAGDEPAESPSE---TPGPSPAGPT 650
           PSE   TP P  A P+ D+  ++P+E   GP P  P+ D+  ++PSE   TP P  A P+
Sbjct: 476 PSERQLTPLPPSAPPSADDNIKTPAEHLRGPLP--PSADDNLKTPSERQLTPLPPSAPPS 533

Query: 651 RDEPAK 656
            D+  K
Sbjct: 534 ADDNIK 539



 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 57/177 (32%), Positives = 86/177 (48%), Gaps = 19/177 (10%)

Query: 514  TPGSPSETPGPSPAGPAGDEPAESPSE-TPGPRPAGPAGDEPAESPSE---TPGPRPAGP 569
            TP     TP P  A P+ D+  ++P+E   GP P  P+ D+  ++PSE   TP P  A P
Sbjct: 902  TPSKRQLTPLPPSAPPSADDNIKTPAERLRGPLP--PSADDNLKTPSERQLTPLPPSAPP 959

Query: 570  AGDEPAESPSE-TPGPSPAGPTRDEPAESPSE---TPGPRPAGPAGDEPAESPSE-TPGP 624
            + D+  ++P+E   GP P  P+ D+  ++PSE   TP P  A  + D+  ++P+E   GP
Sbjct: 960  SADDNIKTPAERLRGPLP--PSADDNLKTPSERQLTPLPPSAPTSADDNIKTPAERLRGP 1017

Query: 625  RPAGPAGDEPAESP----SETPGPSPAGPTRDEPAKAGEAAELQDAEVESSAKSGKP 677
             P  P+ D+  ++P     E     P  P R   A+     E +   V     S KP
Sbjct: 1018 LP--PSADDNLKTPPLATQEAEAEKPRKPKRQRAAEMEPPPEPKRRRVGDVEPSRKP 1072


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 77.4 bits (189), Expect = 4e-14
 Identities = 59/188 (31%), Positives = 80/188 (42%), Gaps = 15/188 (7%)

Query: 497 ENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPR------PAGPA 550
           E G EE+ EG     +  P   + +P      P  +E A+SP+E   P       PA   
Sbjct: 487 EGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEE-AKSPAEAKSPEKEEAKSPAEVK 545

Query: 551 GDEPAESPS--ETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAG 608
             E A+SP+  E   P  A     E A+SP+E   P  A     E A+SP+E   P  A 
Sbjct: 546 SPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAK 605

Query: 609 PAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDAEV 668
               E A+SP+E   P        E A+SP+E   P  A     E AK+ E A+  + E 
Sbjct: 606 SPVKEEAKSPAEAKSP------VKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEE 659

Query: 669 ESSAKSGK 676
             S +  K
Sbjct: 660 AKSPEKAK 667



 Score = 73.2 bits (178), Expect = 8e-13
 Identities = 76/308 (24%), Positives = 116/308 (37%), Gaps = 34/308 (11%)

Query: 381 ESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGGQDPGEAV 440
           E K + +E S +E    E   +     E++    E     +     G +E GG++     
Sbjct: 441 EEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEE----KEAKEEEGKEEEGGEEEE--- 493

Query: 441 QPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGV 500
                   A   ++  K    +E A       S   +    A SPA +  P+   +++  
Sbjct: 494 --------AEGGEEETKSPPAEEAASPEKEAKSPVKEE---AKSPAEAKSPEKEEAKSPA 542

Query: 501 EEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSE 560
           E  +     P++    +  E   P  A     E A+SP+E   P  A     E A+SP+E
Sbjct: 543 EVKS-----PEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAE 597

Query: 561 TPGPRPAGPAGDEPAESPSETPGP------SPAGPTRDEPAESPS--ETPGPRPAGPAGD 612
              P  A     E A+SP+E   P      SPA     E A+SP+  E   P  A     
Sbjct: 598 AKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEK 657

Query: 613 EPAESPSETPGPRPAGPAGDEPAESPSETPGPSP---AGPTRDEPAKAGEAAELQDAEVE 669
           E A+SP +   P  A     E A+SP +    SP     P ++E     +A      E +
Sbjct: 658 EEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAK 717

Query: 670 SSAKSGKP 677
           S  K+  P
Sbjct: 718 SPEKAKSP 725



 Score = 63.9 bits (154), Expect = 5e-10
 Identities = 73/300 (24%), Positives = 115/300 (38%), Gaps = 12/300 (4%)

Query: 375 EPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGGQ 434
           E ++ +E K+ K E  + E+   E   +   E  K +   E  A  +   ++  +E   +
Sbjct: 468 EEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETK-SPPAEEAASPEKEAKSPVKEEA-K 525

Query: 435 DPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSA-AVASGGAQTLALAGSPAPSGHPKA 493
            P EA  P ++   A+   +V+   K    A + A +     +     A SPA    P+ 
Sbjct: 526 SPAEAKSPEKEE--AKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEK 583

Query: 494 GHSENGVEEDTEGRT-GPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGD 552
             S    E  +      P++       E   P+ A     E A+SP+E   P  A     
Sbjct: 584 AKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTK 643

Query: 553 EPAESPSETPGPRPAGPAGDEPAESPSETPGPSP---AGPTRDEPAESPSETPGPRPAGP 609
           E A+SP +   P        E A+SP +    SP     P + E A+SP +   P     
Sbjct: 644 EEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAE-AKSPEKAKSPVKEEA 702

Query: 610 AGDEPAESP--SETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDAE 667
              E A+SP   E   P  A     E A++P +   P        E AK+ E A+  D +
Sbjct: 703 KSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVK 762



 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 87/377 (23%), Positives = 134/377 (35%), Gaps = 28/377 (7%)

Query: 311 EEEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHG 370
           EEEG   +   E   +G   G E +K         +  S E +   P++      A    
Sbjct: 480 EEEGKEEEGGEEEEAEG---GEEETKS----PPAEEAASPEKEAKSPVKEEAKSPAEAKS 532

Query: 371 EDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQE 430
            ++ E  SP E K  +   S  ++    P    + E E+     E    S    ++  +E
Sbjct: 533 PEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAE--VKSPEKAKSPAKE 590

Query: 431 VGGQDPGEAVQP--CRQPLGARVADKVRKRRKVDEGAGDSAAVAS---GGAQTLALAGSP 485
              + P EA  P   + P+          +  V E A   A V S     + T   A SP
Sbjct: 591 EA-KSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSP 649

Query: 486 APSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESP--SETPG 543
                 KA   E    +  E    P +    SP +   P  A     E A+SP   E   
Sbjct: 650 E-----KAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKS 704

Query: 544 PRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPG 603
           P  A     E A+SP +   P        E A+SP +    SP      E A++  +   
Sbjct: 705 PEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKT-LDVKS 763

Query: 604 PRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGP---SPAGPTRDEPAKAGEA 660
           P    PA +E A SP++    +   P  +E  +SP +   P       P ++ P K    
Sbjct: 764 PEAKTPAKEE-ARSPADKFPEKAKSPVKEE-VKSPEKAKSPLKEDAKAPEKEIPKKEEVK 821

Query: 661 AELQDAEVESSAKSGKP 677
           + +++ E     K  +P
Sbjct: 822 SPVKEEEKPQEVKVKEP 838



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 75/330 (22%), Positives = 126/330 (38%), Gaps = 34/330 (10%)

Query: 346 QPRSVEPQDAGPLERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSAS 405
           + +  + ++    E  + +EA G  E+   P + + +   K   S  ++    P    + 
Sbjct: 474 EEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSP 533

Query: 406 EVEKIALNLEGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGA 465
           E E+     E    S    ++  +E   + P EA  P ++   A+   +V+   K    A
Sbjct: 534 EKEEAKSPAE--VKSPEKAKSPAKEEA-KSPPEAKSPEKEE--AKSPAEVKSPEKAKSPA 588

Query: 466 GDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPS 525
            + A  +   A++   A SP          +++ V+E+ +           SP+E   P 
Sbjct: 589 KEEAK-SPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAK-----------SPAEVKSPE 636

Query: 526 PAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPS 585
            A     E A+SP +   P        E A+SP +   P  A     E A+SP +    S
Sbjct: 637 KAKSPTKEEAKSPEKAKSPE------KEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKS 690

Query: 586 PAGPTRDEPAESP--SETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG 643
           P      E A+SP   E   P  A     E A+SP +   P        E A+SP +   
Sbjct: 691 P------EKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEA 744

Query: 644 PSPAGPTRDEPAKAGEAAELQDAEVESSAK 673
            SP      E AK     +++  E ++ AK
Sbjct: 745 KSPEKAKSPEKAK---TLDVKSPEAKTPAK 771



 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 80/385 (20%), Positives = 144/385 (37%), Gaps = 36/385 (9%)

Query: 307 SRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEA 366
           ++  E+  SP   + ++  + ++   E +K    V    + +S   ++A   E+++  E 
Sbjct: 598 AKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPE- 656

Query: 367 GGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRT 426
                 + E  SP+++K      ++  +    P    A   EK    ++  A S    ++
Sbjct: 657 ------KEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKS 710

Query: 427 GTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPA 486
             +E   + P +A  P ++   A+  +K +   K +E      A +   A+TL +    A
Sbjct: 711 PVKEEA-KSPEKAKSPVKEE--AKTPEKAKSPVK-EEAKSPEKAKSPEKAKTLDVKSPEA 766

Query: 487 PSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGP---SPAGPAGDEPAESPSETPG 543
            +  P    + +  ++  E    P +    SP +   P       P  + P +   ++P 
Sbjct: 767 KT--PAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPV 824

Query: 544 PRPAGPAGDEPAESPSETPGPR-PAGPAGDEPAESPSETP----GPSPAGPTRDEPA-ES 597
                P   +  E P +    + PA P  +E  +S  E       P P    + EPA E 
Sbjct: 825 KEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEK 884

Query: 598 PSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESP-----SETPGPSPAGPTRD 652
           P E+        A  E AE   + P P    PA  E  E       +E     P      
Sbjct: 885 PKESKVE-----AKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAK 939

Query: 653 EPAKAGE----AAELQDAEVESSAK 673
           EP+K  E    A E +D + E + K
Sbjct: 940 EPSKPAEKKEAAPEKKDTKEEKAKK 964



 Score = 38.5 bits (88), Expect = 0.021
 Identities = 45/177 (25%), Positives = 64/177 (36%), Gaps = 20/177 (11%)

Query: 491  PKAGHSENGVEEDTEGRTGPK---EGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPA 547
            PK    ++  +E+   +  PK   E       E P  S    A  E AE   + P P   
Sbjct: 851  PKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKV-EAKKEEAEDKKKVPTPEKE 909

Query: 548  GPAGDEPAES--PSETPGPRPAGPAGDEPAESPSETPGPSPAGP----TRDEPAESPSET 601
             PA  E  E   P E        P  D  A+ PS+      A P    T++E A+ P E 
Sbjct: 910  APAKVEVKEDAKPKEKTEVAKKEP-DDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEK 968

Query: 602  PGPRPAGPAGDEPAESPSETPGPRPAGPAGD--EPAESPSETPGPSPAGPTRDEPAK 656
                   P  +  A+   +T    P+ P  +  E + S  +     P   T D+ AK
Sbjct: 969  -------PKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAAK 1018



 Score = 37.7 bits (86), Expect = 0.035
 Identities = 78/384 (20%), Positives = 134/384 (34%), Gaps = 43/384 (11%)

Query: 305  EGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDA-GPLERSQG 363
            E ++  E+  SP   + ++  + ++     +K   +     +  +  P+ A  P++    
Sbjct: 644  EEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAK 703

Query: 364  DEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGS 423
                     + E  SP+++K    E ++  +    P  + A   EK     +   L   S
Sbjct: 704  SPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKS 763

Query: 424  --LRTGTQEVGGQDPGEAVQPCRQPLGARVA--DKVRKRRKVDEGAGD----------SA 469
               +T  +E       +  +  + P+   V   +K +   K D  A +          S 
Sbjct: 764  PEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSP 823

Query: 470  AVASGGAQTLALAGSPAPSGHPKAGHSENGVEE-DTEGRTGPKEGTPGSPSETPGPSPAG 528
                   Q + +   P  +   KA  +    E+ D++    PK+  P    E        
Sbjct: 824  VKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVE----EKKE 879

Query: 529  PAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAES--PSETPGPSP 586
            PA ++P ES  E         A  E AE   + P P    PA  E  E   P E    + 
Sbjct: 880  PAVEKPKESKVE---------AKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAK 930

Query: 587  AGPTRDEPAESPSETPGPRPAGP----AGDEPAESPSETPGPRPAGPAGD-----EPAES 637
              P  D  A+ PS+    + A P      +E A+ P E P         D     EP++ 
Sbjct: 931  KEPD-DAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKP 989

Query: 638  PSETPGPSPAGPTRDE--PAKAGE 659
             +E    S +   +D   P KA E
Sbjct: 990  KAEKAEKSSSTDQKDSKPPEKATE 1013


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 76.6 bits (187), Expect = 7e-14
 Identities = 110/410 (26%), Positives = 132/410 (32%), Gaps = 73/410 (17%)

Query: 299 SLPHPLEGSRKVEEEGSPGDPDHEASTQGR------TCGPEHSKGGGRVD--EGPQPRSV 350
           SL   L  S       +P  P+  A+  G       +  P  + G G     EG    + 
Sbjct: 28  SLESQLAASAAHHHHLAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAP 87

Query: 351 EPQDAGPLERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKI 410
           EP  AG          GG G  RP P SP           RR   P  P P +A    K+
Sbjct: 88  EPPPAGRAR------PGGGGPQRPGPPSP-----------RRPLVPAGPAPPAA----KL 126

Query: 411 ALNLEGCALSQGSLRTGTQEVGGQDP---GEAVQPCRQPLGARVADKVRKRRKVDEGAGD 467
               EG A S   +        G +P   G A       L AR             G G 
Sbjct: 127 RPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGP 186

Query: 468 SAAVASGGAQTLALAGSPAPSGH---PKAGHSENG----------VEEDTEGRTGPKEGT 514
                 G AQTL  + +   S H   P      NG              T  +T P  G 
Sbjct: 187 GKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGA 246

Query: 515 -----PGSPSETPGPSPAGPAGDEPAESPSET----PGPRPAGPAGDEPAESP------- 558
                P +PS    P+PA PA   P   P+      P   PAGP    PA  P       
Sbjct: 247 AAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNG 306

Query: 559 -----SETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDE 613
                +  P P   GPAG     S    PG + A P     AESP       P  PA   
Sbjct: 307 GSAGAAPAPAPAAGGPAG----VSGQPGPGAAAAAPAPGVKAESPKRVVQAAP--PAAQT 360

Query: 614 PAES-PSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAE 662
            A S P+ T      GP       SP+  P P+P  PT      AG   +
Sbjct: 361 LAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQ 410



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 72/254 (28%), Positives = 86/254 (33%), Gaps = 43/254 (16%)

Query: 432 GGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHP 491
           G Q PG    P R  + A  A    K R   EG+  S A     A   A+A  P P+   
Sbjct: 101 GPQRPGPP-SPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAA---AVAAGPEPA--- 153

Query: 492 KAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSP-AGPAGDEPAESPSETPGPRPAGPA 550
                                  P  P++  GP+  A  AG  P   P   PGP P  PA
Sbjct: 154 -----------------------PAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPA 190

Query: 551 GDEPAE----SPSETPGPRPAGPAGDEPAESPSET-PGPSPAGP-TRDEPAESPSETPGP 604
           G   A+    S +       A PA       P+   P P PA P T  +          P
Sbjct: 191 GPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPP 250

Query: 605 RPAGP---AGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAA 661
            PA P   A   PA +P+  P P P  PA    A  P    GP  A P    PA A    
Sbjct: 251 APAAPSPPAAPAPA-APAAAPPPPPPAPA--TLARPPGHPAGPPTAAPAVPPPAAAQNGG 307

Query: 662 ELQDAEVESSAKSG 675
               A   + A  G
Sbjct: 308 SAGAAPAPAPAAGG 321



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 36/114 (31%), Positives = 44/114 (38%), Gaps = 11/114 (9%)

Query: 567 AGPAGDEPAE-SPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGP- 624
           AG  G+     SP+   G  PA P    P  +P   P  R A P G  P     + PGP 
Sbjct: 55  AGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGR-ARPGGGGP-----QRPGPP 108

Query: 625 ---RPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDAEVESSAKSG 675
              RP  PAG  P  +    P    AG     PA A  AA  + A    +  +G
Sbjct: 109 SPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAG 162


>gi|87196339 collagen, type VI, alpha 1 precursor [Homo sapiens]
          Length = 1028

 Score = 76.6 bits (187), Expect = 7e-14
 Identities = 63/187 (33%), Positives = 71/187 (37%), Gaps = 26/187 (13%)

Query: 481 LAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSE 540
           + G P P G P A            G  G K G PG+  E   P  +GP+GDE    P E
Sbjct: 354 IQGPPGPKGDPGAF-----------GLKGEK-GEPGADGEAGRPGSSGPSGDEG--QPGE 399

Query: 541 TPGPRPAGPAGDE----PAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAE 596
              P   G AGDE    P  +P E  GP   GP G      P   PG   AGP  D+  E
Sbjct: 400 PGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGE--AGPQGDQGRE 457

Query: 597 SPSETPG-PRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPA 655
            P   PG P  AGP G +        PG       G   A  P+  PG       R E  
Sbjct: 458 GPVGVPGDPGEAGPIGPKGYRGDEGPPGSE-----GARGAPGPAGPPGDPGLMGERGEDG 512

Query: 656 KAGEAAE 662
            AG   E
Sbjct: 513 PAGNGTE 519



 Score = 63.9 bits (154), Expect = 5e-10
 Identities = 100/355 (28%), Positives = 130/355 (36%), Gaps = 42/355 (11%)

Query: 330 CGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGEDRPEPLSPKESKKRKLEL 389
           C P     G R D G +    +P   G     +  EAG  G  RP  L P   +  K E 
Sbjct: 252 CQPARGPPGLRGDPGFEGERGKPGLPG-----EKGEAGDPG--RPGDLGPVGYQGMKGEK 304

Query: 390 SRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLR-TGTQEVGGQDPGEAVQPCRQPLG 448
             R +  +  GP+     EK    ++G    +G +   G     G    + +Q    P G
Sbjct: 305 GSRGEKGSR-GPKGYKG-EKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKG 362

Query: 449 ARVADKVRKRRKVDEGAGDSAAV--ASGGAQTLALAGSPAPSGHP-KAGHSENGVEEDTE 505
              A  + K  K + GA   A    +SG +      G P P G   +AG   N   +   
Sbjct: 363 DPGAFGL-KGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAP 421

Query: 506 G-RTGPKE----GTPGSPSETPGPSPAGPAGDEPAESPSETPG-PRPAGPAGDEPAESPS 559
           G R GP E    GTPG+      P  AGP GD+  E P   PG P  AGP G +      
Sbjct: 422 GERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDE 481

Query: 560 ETPG-------PRPAGPAGDEPAESPSETPGPSPAGP-----------TRDEPAESPSE- 600
             PG       P PAGP GD          GP+  G             R  P  + ++ 
Sbjct: 482 GPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKG 541

Query: 601 TPGPR-PAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG-PSPAGPTRDE 653
            PG +   G AGD P +  ++       G  G    E P   PG   P GP   E
Sbjct: 542 YPGLKGDEGEAGD-PGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPDECE 595


>gi|157074225 nuclear pore complex interacting protein-like 3 [Homo
           sapiens]
          Length = 678

 Score = 76.3 bits (186), Expect = 9e-14
 Identities = 57/155 (36%), Positives = 86/155 (55%), Gaps = 18/155 (11%)

Query: 514 TPGSPSETPGPSPAGPAGDEPAESPSE-TPGPRPAGPAGDEPAESPSE---TPGPRPAGP 569
           TP     TP P  A P+ D+  ++P+E   GP P  P+ D+  ++PSE   TP P  A P
Sbjct: 387 TPSERQLTPLPPSAPPSADDNIKTPAERLRGPLP--PSADDNLKTPSERQLTPLPPSAPP 444

Query: 570 AGDEPAESPSE-TPGPSPAGPTRDEPAESPSE---TPGPRPAGPAGDEPAESPSE-TPGP 624
           + D+  ++P+E   GP P  P+ D+  ++PSE   TP P  A P+ D+  ++P+E   GP
Sbjct: 445 SADDNIKTPAERLRGPLP--PSADDNLKTPSERQLTPLPPSAPPSADDNIKTPAERLRGP 502

Query: 625 RPAGPAGDEPAESPSE---TPGPSPAGPTRDEPAK 656
            P  P+ D+  ++PSE   TP P  A P+ D+  K
Sbjct: 503 LP--PSADDNLKTPSERQLTPLPPSAPPSADDNIK 535



 Score = 39.7 bits (91), Expect = 0.009
 Identities = 47/196 (23%), Positives = 68/196 (34%), Gaps = 29/196 (14%)

Query: 487 PSGHPKAGHSENGVEEDTEGRTGPKEG----TPGSPSETPGPSPAGPAGDEPAESPSE-T 541
           PS  P A  +     E   G   P       TP     TP P  A P+ D+  ++P+E  
Sbjct: 482 PSAPPSADDNIKTPAERLRGPLPPSADDNLKTPSERQLTPLPPSAPPSADDNIKTPAERL 541

Query: 542 PGPRPAGPAGDEPAESP----SETPGPRPAGPAGDEPAE-SPSETPGPSPAG-------P 589
            GP P  P+ D+  ++P     E    +P  P     AE  P   P     G       P
Sbjct: 542 RGPLP--PSADDNLKTPPLATQEAEAEKPRKPKRQRAAEMEPPPEPKRRRVGDVEPSRKP 599

Query: 590 TRDEPAESPSETPGPRPAGPAGDEPAESPS---------ETPGPRPAGPAGDEPAESPSE 640
            R   A+    +P P+       EP+  P           +P P+       EP+  P  
Sbjct: 600 KRRRAADVEPSSPEPKRRRVGDVEPSRKPKRRRAADVEPSSPEPKRRRVGDVEPSRKPKR 659

Query: 641 TPGPSPAGPTRDEPAK 656
               +   P+  EP +
Sbjct: 660 RRA-ADVEPSLPEPKR 674


>gi|139394646 iroquois homeobox protein 5 [Homo sapiens]
          Length = 483

 Score = 75.5 bits (184), Expect = 2e-13
 Identities = 67/203 (33%), Positives = 85/203 (41%), Gaps = 20/203 (9%)

Query: 463 EGAGDSAAVASGGAQTLALAGSPAPSGHPK-AGHSENGVEEDTEGRTGPKEGTPGS---P 518
           E  GD     +GGA+  A +G     G P  AG    G   D++ +  P EG   +   P
Sbjct: 208 EDKGDPEGPEAGGAEQKAASGCERLQGPPTPAGKETEGSLSDSDFKEPPSEGRLDALQGP 267

Query: 519 SETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESP 578
             T GPSPAGPA    AE P+      P  PAG  PA  P    G  P GP G     SP
Sbjct: 268 PRTGGPSPAGPAAARLAEDPA------PHYPAG-APAPGPHPAAGEVPPGPGGPSVIHSP 320

Query: 579 SETPGPSP-AGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGP---RPAGPAGDEP 634
              P P+  A P     AE  + +   +  G  G+E +  P   PGP   +  G +   P
Sbjct: 321 PPPPPPAVLAKPKLWSLAEIATSSDKVKDGG-GGNEGSPCP-PCPGPIAGQALGGSRASP 378

Query: 635 AESPSETPG---PSPAGPTRDEP 654
           A +PS +P    P P G     P
Sbjct: 379 APAPSRSPSAQCPFPGGTVLSRP 401



 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 44/129 (34%), Positives = 52/129 (40%), Gaps = 18/129 (13%)

Query: 532 DEPA--ESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGP 589
           DEP   E   +  GP  AG A  + A       GP    PAG E   S S++    P   
Sbjct: 202 DEPQKPEDKGDPEGPE-AGGAEQKAASGCERLQGPPT--PAGKETEGSLSDSDFKEPPSE 258

Query: 590 TRDEPAESPSETPGPRPAGPAGDEPAESP-------SETPGPRPA------GPAGDEPAE 636
            R +  + P  T GP PAGPA    AE P       +  PGP PA      GP G     
Sbjct: 259 GRLDALQGPPRTGGPSPAGPAAARLAEDPAPHYPAGAPAPGPHPAAGEVPPGPGGPSVIH 318

Query: 637 SPSETPGPS 645
           SP   P P+
Sbjct: 319 SPPPPPPPA 327



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 36/106 (33%), Positives = 44/106 (41%), Gaps = 14/106 (13%)

Query: 552 DEPA--ESPSETPGPRPAGPAGDEPAESPSETPGP-SPAGPTRDEPAESPSETPGPRPAG 608
           DEP   E   +  GP  AG A  + A       GP +PAG    E   S S++    P  
Sbjct: 202 DEPQKPEDKGDPEGPE-AGGAEQKAASGCERLQGPPTPAGK---ETEGSLSDSDFKEPPS 257

Query: 609 PAGDEPAESPSETPGPRPAGPAGDEPAESP-------SETPGPSPA 647
               +  + P  T GP PAGPA    AE P       +  PGP PA
Sbjct: 258 EGRLDALQGPPRTGGPSPAGPAAARLAEDPAPHYPAGAPAPGPHPA 303



 Score = 37.0 bits (84), Expect = 0.060
 Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 5/80 (6%)

Query: 572 DEPA--ESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGP 629
           DEP   E   +  GP  AG    + A       GP    PAG E   S S++    P   
Sbjct: 202 DEPQKPEDKGDPEGPE-AGGAEQKAASGCERLQGPPT--PAGKETEGSLSDSDFKEPPSE 258

Query: 630 AGDEPAESPSETPGPSPAGP 649
              +  + P  T GPSPAGP
Sbjct: 259 GRLDALQGPPRTGGPSPAGP 278


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 74.7 bits (182), Expect = 3e-13
 Identities = 78/261 (29%), Positives = 100/261 (38%), Gaps = 38/261 (14%)

Query: 436  PGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGH 495
            P  AV P  +P     A         +E    +AAV +    T   A  P P        
Sbjct: 1029 PAAAVPPPEEPTSPAAAVPTP-----EEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAA 1083

Query: 496  SENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPR-PAGPAGDEP 554
            +    EE T     P    P +P E   P+ A P  +EPA   +  P P  PA PA   P
Sbjct: 1084 AVPTPEEPTS----PAAAVP-TPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVP 1138

Query: 555  AESPSETPGPRPAGPAGDEPAES------PSETPGPSPAGPTRDEPAESPSETPG----P 604
              +P E   P PA P  +E A +      P E+  P+ A PT   PAES S         
Sbjct: 1139 --TPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPT---PAESASFAAVVATLE 1193

Query: 605  RPAGPAGDEPAESP-----SETPGPRPAGPAGDEPAE------SPSETPGPSPAGPTRDE 653
             P  PA   P  +       E   P  + P  +EPA       +P E   P+ A PT +E
Sbjct: 1194 EPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEE 1253

Query: 654  PAKAGEAAELQDAEVESSAKS 674
            P  +  AA L   E+ S A S
Sbjct: 1254 PTSSA-AAVLTPEELSSPAAS 1273



 Score = 74.3 bits (181), Expect = 3e-13
 Identities = 62/198 (31%), Positives = 78/198 (39%), Gaps = 25/198 (12%)

Query: 501  EEDTEGRTGPKEGTPGSPSET-PGPS-PAGPAGDEPAESPSETPGPRPAGPAGDEPAE-- 556
            E DT          P SP+   P P  P  PA   P  +P E   P  A P  +EP    
Sbjct: 986  EPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVP--TPEEPTSPAAAVPPPEEPTSPA 1043

Query: 557  ----SPSETPGPRPAGPAGDEPAE------SPSETPGPSPAGPTRDEPAE------SPSE 600
                +P E   P  A P  +EP        +P E   P+ A PT +EP        +P E
Sbjct: 1044 AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE 1103

Query: 601  TPGPRPAGPAGDEPAESPSETPGP-RPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGE 659
               P  A P  +EPA   +  P P  PA PA   P  +P E   P+PA PT +E A A  
Sbjct: 1104 PTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVP--TPEEPAFPAPAVPTPEESASAAV 1161

Query: 660  AAELQDAEVESSAKSGKP 677
            A    +     +A    P
Sbjct: 1162 AVPTPEESASPAAAVPTP 1179



 Score = 73.9 bits (180), Expect = 4e-13
 Identities = 67/213 (31%), Positives = 87/213 (40%), Gaps = 25/213 (11%)

Query: 462  DEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSET 521
            +E A  +AAV +    T   A  P P        +    EE T         +P +   T
Sbjct: 998  EEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPT---------SPAAAVPT 1048

Query: 522  PGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGP-RPAGPAGDEPAESPSE 580
            P   P  PA   P  +P E   P  A P  +EP    +  P P  P  PA   P  +P E
Sbjct: 1049 P-EEPTSPAAAVP--TPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP--TPEE 1103

Query: 581  TPGPSPAGPTRDEPAESPSETPGP-RPAGPAGDEPAESPSETPGPRPAGPAGDEPAE--- 636
               P+ A PT +EPA   +  P P  PA PA   P  +P E   P PA P  +E A    
Sbjct: 1104 PTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVP--TPEEPAFPAPAVPTPEESASAAV 1161

Query: 637  ---SPSETPGPSPAGPTRDEPAK-AGEAAELQD 665
               +P E+  P+ A PT  E A  A   A L++
Sbjct: 1162 AVPTPEESASPAAAVPTPAESASFAAVVATLEE 1194



 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 66/224 (29%), Positives = 86/224 (38%), Gaps = 27/224 (12%)

Query: 461  VDEGAGDSAAVASGGAQTLALAGSPAPSGHPK-AGHSENGVEEDTEGRTGPKEGTPGSPS 519
            V EG    AAV+S      A+A +    G    AG S              ++GTP  P 
Sbjct: 916  VPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPV 975

Query: 520  ETPGPSPAGPAGDEPA----ESPSETPGPRPAGPAGDEPAE------SPSETPGPRPAGP 569
             TP  +   P   + A     +P E   P  A P  +EP        +P E   P  A P
Sbjct: 976  -TPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP 1034

Query: 570  AGDEPAE------SPSETPGPSPAGPTRDEPAE------SPSETPGPRPAGPAGDEPAES 617
              +EP        +P E   P+ A PT +EP        +P E   P  A P  +EP   
Sbjct: 1035 PPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSP 1094

Query: 618  PSETPGP-RPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEA 660
             +  P P  P  PA   P  +P E   P+ A PT +EPA    A
Sbjct: 1095 AAAVPTPEEPTSPAAAVP--TPEEPASPAAAVPTPEEPASPAAA 1136



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 40/171 (23%), Positives = 56/171 (32%), Gaps = 10/171 (5%)

Query: 508  TGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPA 567
            + P+E  P   +       +  AG  P  +      P        E   +P+ T      
Sbjct: 927  SSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEE 986

Query: 568  GPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPR-PAGPAGDEPAESPSETPGPRP 626
                     +P E   P+ A PT +EP    +  P P  P  PA   P       P   P
Sbjct: 987  PDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP-------PPEEP 1039

Query: 627  AGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDAEVESSAKSGKP 677
              PA   P  +P E   P+ A PT +EP     A    +     +A    P
Sbjct: 1040 TSPAAAVP--TPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTP 1088


>gi|62000702 diacylglycerol kinase kappa [Homo sapiens]
          Length = 1271

 Score = 74.3 bits (181), Expect = 3e-13
 Identities = 51/153 (33%), Positives = 65/153 (42%), Gaps = 17/153 (11%)

Query: 505 EGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGP 564
           +G   P++G    P+E+P P P  P        P   P P PA P   E +  P   P P
Sbjct: 9   QGTAPPQDGE--QPAESPEPPPPWPP-------PPPPPAPPPAPPLLSEASPEPIPEPCP 59

Query: 565 RPA-GPAGDEPAESPSET-PGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETP 622
             A GP  +  +ES +E    P+P      EPA  P+  P P PA     EPA  P+  P
Sbjct: 60  ELAPGPCPEATSESATELYTEPTP------EPATEPASEPAPEPATEPAPEPATEPAPEP 113

Query: 623 GPRPAGPAGDEPAESPSETPGPSPAGPTRDEPA 655
            P PA  +  EP   P+    P PA     E A
Sbjct: 114 APEPATESAPEPTPEPALESVPEPAPELTPEVA 146



 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 54/165 (32%), Positives = 65/165 (39%), Gaps = 16/165 (9%)

Query: 501 EEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPA-GPAGDEPAESPS 559
           E+  E    P    P  P   P P PA P   E +  P   P P  A GP  +  +ES +
Sbjct: 18  EQPAESPEPPPPWPP--PPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATSESAT 75

Query: 560 ET---PGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAE 616
           E    P P PA     EPA  P+  P P        EPA  P+  P P PA  +  EP  
Sbjct: 76  ELYTEPTPEPATEPASEPAPEPATEPAP--------EPATEPAPEPAPEPATESAPEPTP 127

Query: 617 SPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAA 661
            P+    P PA      P  +P   P P+P   T   P    EAA
Sbjct: 128 EPALESVPEPAPEL--TPEVAPELAPEPTPEPVTELAPEFCPEAA 170



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 46/150 (30%), Positives = 54/150 (36%), Gaps = 18/150 (12%)

Query: 518 PSETPGPSP--AGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPA 575
           P   PGP P     +  E    P+  P   PA     EPA  P+  P   PA     EPA
Sbjct: 59  PELAPGPCPEATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPAPEPA 118

Query: 576 ESPSETPGPSPAGPTRDEPAE------SPSETPGPRPAGPAGDEPAESPSETP--GPRPA 627
              +  P P PA  +  EPA       +P   P P P       P   P   P   P PA
Sbjct: 119 TESAPEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPA 178

Query: 628 GPAGDEPAE--------SPSETPGPSPAGP 649
                 P +        SPS +P PSP  P
Sbjct: 179 PCLLQCPVDTRERGLKTSPSPSPSPSPRTP 208



 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 45/150 (30%), Positives = 56/150 (37%), Gaps = 15/150 (10%)

Query: 486 APSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPR 545
           AP   P+A  SE+  E  TE    P       P+  P   PA     EPA  P+    P 
Sbjct: 62  APGPCPEAT-SESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPA----PE 116

Query: 546 PAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDE--PAESPSETPG 603
           PA  +  EP   P+    P PA     E A   +  P P P      E  P  +P   P 
Sbjct: 117 PATESAPEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPS 176

Query: 604 PRP--------AGPAGDEPAESPSETPGPR 625
           P P            G + + SPS +P PR
Sbjct: 177 PAPCLLQCPVDTRERGLKTSPSPSPSPSPR 206


>gi|48762934 alpha 2 type I collagen [Homo sapiens]
          Length = 1366

 Score = 73.9 bits (180), Expect = 4e-13
 Identities = 107/369 (28%), Positives = 128/369 (34%), Gaps = 106/369 (28%)

Query: 314  GSPGDPDHEASTQGRTCGPEHSKG--GGRVDEGPQPRSVEPQDAGPL----ERSQGDEAG 367
            G PG P           GP   +G  G R D+GP  R+ E    GP     E+    EAG
Sbjct: 805  GPPGPP-----------GPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAG 853

Query: 368  GHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTG 427
              G                        PP  PGPQ       I L L G   S+G    G
Sbjct: 854  TAG------------------------PPGTPGPQGLLGAPGI-LGLPG---SRGE--RG 883

Query: 428  TQEVGGQ--DPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSP 485
               V G   +PG        PLG                AG   A    GA      GSP
Sbjct: 884  LPGVAGAVGEPG--------PLGI---------------AGPPGARGPPGA-----VGSP 915

Query: 486  APSGHP-KAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGP 544
              +G P +AG   N   +   GR    +G PG   E   P   GP G   A  P    GP
Sbjct: 916  GVNGAPGEAGRDGNPGNDGPPGR----DGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGP 971

Query: 545  R----------PAGPAGDEPAESPSETPGPRP-AGPAGDEPAESPSETPG---------- 583
                       P+GP G   A  P    GP+   G  G+   + P   PG          
Sbjct: 972  AGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGL 1031

Query: 584  PSPAGPTRDEPAESPSETPGPR-PAGPAGDEPAESPSETPGP-RPAGPAGDEPAESPSET 641
            P  AG   D+ A       GPR PAGP+G    +  +  PG   PAG  G +  + P+  
Sbjct: 1032 PGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAGP 1091

Query: 642  PG-PSPAGP 649
            PG P P GP
Sbjct: 1092 PGPPGPPGP 1100



 Score = 67.4 bits (163), Expect = 4e-11
 Identities = 93/291 (31%), Positives = 115/291 (39%), Gaps = 39/291 (13%)

Query: 398 EPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGGQDP----GEAVQPCRQPLGARVAD 453
           EPGP + S+ E       G A  QG      +E G + P    G A  P   P G R + 
Sbjct: 347 EPGP-AGSKGESGNKGEPGSAGPQGPPGPSGEE-GKRGPNGEAGSAGPP--GPPGLRGSP 402

Query: 454 KVRKRRKVDEGAGDSAAVASGGAQTLA-LAGSPAPSGHP-KAGHSENGVEEDTEGRTGP- 510
             R     D  AG      S GA   A + G    +G P + G         + G  GP 
Sbjct: 403 GSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPA 462

Query: 511 -KEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPR-PAGPAGDEPAESPSETPGPRPA- 567
            KEG  G P     P P GPAG          PGP+ P G  G    +  +   G R A 
Sbjct: 463 GKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAP 522

Query: 568 GPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPG----PRPAGPAGD--EPAES--PS 619
           GP G+  A+ P     P P G    +  + P   PG    P P+GPAG+  +P E     
Sbjct: 523 GPDGNNGAQGP-----PGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHG 577

Query: 620 ETPGPRPAGPAGDE--PAESPSETP-------GPS-PAGP--TRDEPAKAG 658
           E   P PAGP G+   P ES +  P       GPS P GP   + EP   G
Sbjct: 578 EFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVG 628



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 107/414 (25%), Positives = 138/414 (33%), Gaps = 74/414 (17%)

Query: 297 PSSLPHPLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKG--GGRVDEGPQPRSVEPQD 354
           P  +P P+  +      G  G+P    S      G   +KG  G    +GP   S E   
Sbjct: 326 PRGIPGPVGAAGATGARGLVGEPGPAGSK-----GESGNKGEPGSAGPQGPPGPSGEEGK 380

Query: 355 AGPLERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIA--- 411
            GP       EAG  G   P  L      +       R      PG + AS    +    
Sbjct: 381 RGP-----NGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPN 435

Query: 412 -----------LNLEGCALSQGSLRTGTQEVGGQDPGEAVQPCR-QPLGAR-----VADK 454
                      +   G   S G++    +E     PG   +P    P GAR     +   
Sbjct: 436 GDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFP 495

Query: 455 VRKRRKVDEGA-GDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEG 513
             K    D G  GD       GA+     G+P P G+  A        +  +G  G ++G
Sbjct: 496 GPKGPTGDPGKNGDKGHAGLAGAR-----GAPGPDGNNGAQGPPG--PQGVQGGKG-EQG 547

Query: 514 TPGSPSETPGPSPAGPAGD--EPAESP--SETPGPRPAGPAGDEPAESPSETPGPRPAGP 569
            PG P     P P+GPAG+  +P E     E   P PAGP G+     P E+    P GP
Sbjct: 548 PPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGP--PGESGAAGPTGP 605

Query: 570 AGDEPAESPSETPG----PSPAGPTRDEPAESPSETPGPRPAG----------------- 608
            G      P    G    P   G         PS  PG R A                  
Sbjct: 606 IGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGE 665

Query: 609 ---PAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGE 659
              P  D    +P     P PAG  GD   E+ +  P   PAGP R  P + GE
Sbjct: 666 IGNPGRDGARGAPGAVGAPGPAGATGDR-GEAGAAGPA-GPAGP-RGSPGERGE 716



 Score = 63.9 bits (154), Expect = 5e-10
 Identities = 65/204 (31%), Positives = 76/204 (37%), Gaps = 32/204 (15%)

Query: 483 GSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETP 542
           G+P   G P A   ENG    T G+TG + G PG       P PAG  G + +  P    
Sbjct: 193 GAPGVKGEPGAP-GENG----TPGQTGAR-GLPGERGRVGAPGPAGARGSDGSVGPVGPA 246

Query: 543 GP-RPAGPAGDEPAESP-SETPGPRPAGPAGDEPAESPSETPGPS-PAGPTRDEPAESPS 599
           GP   AGP G   A  P  E      AGPAG          PG S P GP  +  A   +
Sbjct: 247 GPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLT 306

Query: 600 ET---------------PGPR----PAGPAGDEPAESPSETPGPR----PAGPAGDEPAE 636
                            PGPR    P G AG   A      PGP      +G  G+  + 
Sbjct: 307 GAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSA 366

Query: 637 SPSETPGPSPAGPTRDEPAKAGEA 660
            P   PGPS     R    +AG A
Sbjct: 367 GPQGPPGPSGEEGKRGPNGEAGSA 390



 Score = 63.2 bits (152), Expect = 8e-10
 Identities = 67/211 (31%), Positives = 80/211 (37%), Gaps = 40/211 (18%)

Query: 481 LAGSPAPSGHPKAGHSENGVEEDTEGRTGPK--EGTPGSPSETPGPSPAGPAGDEPAESP 538
           L+G   P G+P A    NG+    +G  G     G PG P     P P G AG   A   
Sbjct: 290 LSGPVGPPGNPGA----NGLT-GAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGL 344

Query: 539 SETPGPRPAGPAGDEPAESPSETPGPR-PAGPAGDEPAESP------SETPGP-----SP 586
              PG  PAG  G+   +    + GP+ P GP+G+E    P      +  PGP     SP
Sbjct: 345 VGEPG--PAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSP 402

Query: 587 A--------------GPTRDEPAESPSETPGPR-PAGPAGDEPAESPSETPG-PRPAGPA 630
                          GP     A  P+   GP   AG  G+     P   PG P   GPA
Sbjct: 403 GSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPA 462

Query: 631 GDE-PAESPSETPGPSPAGP--TRDEPAKAG 658
           G E P   P     P P GP   R EP   G
Sbjct: 463 GKEGPVGLPGIDGRPGPIGPAGARGEPGNIG 493



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 103/368 (27%), Positives = 124/368 (33%), Gaps = 47/368 (12%)

Query: 312 EEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAG-------------PL 358
           E G PG    E+   G T GP  S+G      GP     EP   G             P 
Sbjct: 590 ERGPPG----ESGAAGPT-GPIGSRGPSG-PPGPDGNKGEPGVVGAVGTAGPSGPSGLPG 643

Query: 359 ERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSAS--EVEKIALNLEG 416
           ER      GG GE     L  +     +            PGP  A+    E  A    G
Sbjct: 644 ERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAG 703

Query: 417 CALSQGSLRTGTQ-EVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGG 475
            A  +GS   G + EVG   P     P     GA      +  R      G++  V   G
Sbjct: 704 PAGPRGS--PGERGEVGPAGPNGFAGPA----GAAGQPGAKGERGAKGPKGENGVVGPTG 757

Query: 476 AQTLALAGSPAPSGHP-KAGHSENGVEEDTEGRTGP--KEGTPGSPSETPGPSPAGPAGD 532
              +  AG   P+G P  AG   +G      G  G   + G PG    +  P P GPAG 
Sbjct: 758 P--VGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGK 815

Query: 533 EPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSP--AGPT 590
           E    P    G  P G  G+  A  P    G +  GP+G+     P  TPGP      P 
Sbjct: 816 EGLRGPRGDQG--PVGRTGEVGAVGPPGFAGEK--GPSGEAGTAGPPGTPGPQGLLGAPG 871

Query: 591 RDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAG-- 648
                 S  E   P  AG  G+      +  PG R  GP G     SP     P  AG  
Sbjct: 872 ILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGAR--GPPG--AVGSPGVNGAPGEAGRD 927

Query: 649 --PTRDEP 654
             P  D P
Sbjct: 928 GNPGNDGP 935



 Score = 49.7 bits (117), Expect = 9e-06
 Identities = 41/132 (31%), Positives = 48/132 (36%), Gaps = 9/132 (6%)

Query: 528 GPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPA 587
           GPAGD         PGP P     D P   P     P P G  G+  A+   +  G  P 
Sbjct: 33  GPAGDRGPRGERGPPGP-PGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPG 91

Query: 588 GPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPA 647
                 P   P     P P G  G  PA  P E   P   GPAG   A  P+  PG +  
Sbjct: 92  PMGLMGPRGPPGAAGAPGPQGFQG--PAGEPGE---PGQTGPAG---ARGPAGPPGKAGE 143

Query: 648 GPTRDEPAKAGE 659
                +P + GE
Sbjct: 144 DGHPGKPGRPGE 155



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 49/156 (31%), Positives = 55/156 (35%), Gaps = 19/156 (12%)

Query: 497 ENGVEEDTEGRTGPK--EGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEP 554
           E  V +   G  GP+   G PG P       P GP G      P   PGP   G      
Sbjct: 27  EETVRKGPAGDRGPRGERGPPGPPGRDGEDGPTGPPG------PPGPPGPPGLGGNFAAQ 80

Query: 555 AESPSETPGPRPAGPAGDEPAESPSETPGPSPAG--PTRDEPAESPSETPGPR----PAG 608
            +      GP P G  G  P   P     P P G      EP E P +T GP     PAG
Sbjct: 81  YDGKGVGLGPGPMGLMG--PRGPPGAAGAPGPQGFQGPAGEPGE-PGQT-GPAGARGPAG 136

Query: 609 PAGDEPAESPSETPG-PRPAGPAGDEPAESPSETPG 643
           P G    +     PG P   G  G + A     TPG
Sbjct: 137 PPGKAGEDGHPGKPGRPGERGVVGPQGARGFPGTPG 172



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 57/198 (28%), Positives = 71/198 (35%), Gaps = 37/198 (18%)

Query: 483 GSPAPSGHPKAGHSEN--------GVEEDTEGRTGPKEGTPGSPSETPGPS----PAGPA 530
           G P P G P  G +          G+     G  GP+ G PG+    PGP     PAG  
Sbjct: 63  GPPGPPGPPGLGGNFAAQYDGKGVGLGPGPMGLMGPR-GPPGAAG-APGPQGFQGPAGEP 120

Query: 531 GDEPAESPSETPGPR-PAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG-PSPAG 588
           G+     P+   GP  P G AG++        PG R  G  G + A     TPG P   G
Sbjct: 121 GEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGER--GVVGPQGARGFPGTPGLPGFKG 178

Query: 589 PTRDEPAESPSETPGPRPAGPAGDEPAESPSETPG----------------PRPAGPAGD 632
                  +     PG    G  G+  A   + TPG                P PAG  G 
Sbjct: 179 IRGHNGLDGLKGQPGA--PGVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGS 236

Query: 633 EPAESPSETPGP-SPAGP 649
           + +  P    GP   AGP
Sbjct: 237 DGSVGPVGPAGPIGSAGP 254



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 54/165 (32%), Positives = 65/165 (39%), Gaps = 20/165 (12%)

Query: 506 GRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPG--PRPAGPAGDEPAESPSETPG 563
           GR G ++G  G P     P P G  G+  A+   +  G  P P G  G  P   P     
Sbjct: 51  GRDG-EDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPGPMGLMG--PRGPPGAAGA 107

Query: 564 PRP---AGPAGDEPAESPSETPGPS----PAGPTRDEPAESPSETPG-PRPAGPAGDEPA 615
           P P    GPAG EP E P +T GP+    PAGP      +     PG P   G  G + A
Sbjct: 108 PGPQGFQGPAG-EPGE-PGQT-GPAGARGPAGPPGKAGEDGHPGKPGRPGERGVVGPQGA 164

Query: 616 ESPSETPG-PRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGE 659
                TPG P   G  G    +     PG   A   + EP   GE
Sbjct: 165 RGFPGTPGLPGFKGIRGHNGLDGLKGQPG---APGVKGEPGAPGE 206


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 73.9 bits (180), Expect = 4e-13
 Identities = 99/356 (27%), Positives = 125/356 (35%), Gaps = 46/356 (12%)

Query: 312  EEGSPGDPDHEASTQGRTC-GPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEA-GGH 369
            E GSPG P        R   GP  S G    + GP   S  P   GP   +    A G  
Sbjct: 862  ERGSPGGPGAAGFPGARGLPGPPGSNG----NPGPPGPSGSPGKDGPPGPAGNTGAPGSP 917

Query: 370  GEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQ 429
            G   P+  + +  +K        + PP  PGP          L + G   ++G    G  
Sbjct: 918  GVSGPKGDAGQPGEKGS---PGAQGPPGAPGP----------LGIAGITGARGL--AGPP 962

Query: 430  EVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSG 489
             + G       Q  +   G   A+ +   R      G      + G       G+P   G
Sbjct: 963  GMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEP--GRDGNPGSDG 1020

Query: 490  HPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGP-SPAGPAGDEPAESPSETPGPRPA- 547
             P    S  G  +  E  +    G PG P   PGP  PAG +GD     P+   GP  A 
Sbjct: 1021 LPGRDGSPGGKGDRGENGSPGAPGAPGHPGP-PGPVGPAGKSGDRGESGPA---GPAGAP 1076

Query: 548  GPAGDEPAESPSETPGPR-PAGPAGDEPAES-------PSETPGPSPAGPTRDEPAESPS 599
            GPAG   A  P    GPR   G  G+  A         P     P   GP   + A    
Sbjct: 1077 GPAGSRGAPGPQ---GPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSP 1133

Query: 600  ETPGPR-PAGPAGDEPAESPSETPGP-RPAGPAGDEPAESPSETPG----PSPAGP 649
               GPR P GP+G    +  S  PGP  P GP G+        +PG    P P GP
Sbjct: 1134 GPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGP 1189



 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 69/226 (30%), Positives = 82/226 (36%), Gaps = 36/226 (15%)

Query: 472 ASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGR-TGPKEGTPGSPSETPGPSPAGPA 530
           A G A     AG P   G P  G    G+     G  +  K G PGS  E+  P P GP+
Sbjct: 511 APGPAGPRGAAGEPGRDGVP-GGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPS 569

Query: 531 GDEPAESPSETPGPRP-----------AGPAGDEPAESPSET--PGPR----PAGPAGDE 573
           G          PGP+             GP G  P   P +    GP+    P GP GD+
Sbjct: 570 GPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDK 629

Query: 574 PAESPSETPGPSPAGPTRDEPAES--PSETPGPR-----PAGPAGDEPAESPSE------ 620
               P    G      T   P E+  P E PGP+     P  P G   A +P E      
Sbjct: 630 GDTGPPGPQGLQGLPGTGGPPGENGKPGE-PGPKGDAGAPGAPGGKGDAGAPGERGPPGL 688

Query: 621 --TPGPR-PAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAEL 663
              PG R  AGP G E  +  +  PGP  A  T       GE   L
Sbjct: 689 AGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGL 734



 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 108/369 (29%), Positives = 127/369 (34%), Gaps = 65/369 (17%)

Query: 313 EGSPGDPDHEASTQGRTC--GPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHG 370
           +G PG P  +  + GR    GP   +G   V   P P+     D  P    +  E GG G
Sbjct: 548 DGKPGPPGSQGES-GRPGPPGPSGPRGQPGVMGFPGPKG---NDGAP---GKNGERGGPG 600

Query: 371 EDRPEPLSPKESKKRKLELSRREQP-PTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQ 429
              P+    K       E   +  P PT PG             L+G          GT 
Sbjct: 601 GPGPQGPPGKNG-----ETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLP--------GT- 646

Query: 430 EVGGQDPGEAVQPCRQ-PLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPS 488
              G  PGE  +P    P G   A           G GD+ A    G     LAG+P   
Sbjct: 647 ---GGPPGENGKPGEPGPKGDAGAPGA------PGGKGDAGAPGERGPP--GLAGAPGLR 695

Query: 489 GHPKAGHSENGVEEDTEGRTGPK--EGTPG---SPSETPGPSPAGPAGDEPAESPSETPG 543
           G       E G  +   G  GP    GTPG    P E  G    GP GD+      E  G
Sbjct: 696 GGAGPPGPEGG--KGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDK-----GEPGG 748

Query: 544 PRPAGPAGDEPAESPSETPGPR-PAGPAGDEPAESPSETPG-PSPAGPTRDEPAESPSET 601
           P   G  G +    P+   GP  PAG  GD   +     PG P  AGP R  P E   ET
Sbjct: 749 PGADGVPGKDGPRGPTGPIGPPGPAGQPGD---KGEGGAPGLPGIAGP-RGSPGER-GET 803

Query: 602 PGPRPAG----------PAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTR 651
             P PAG          P G     +P E     P G AG      P+  PGP      R
Sbjct: 804 GPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGER 863

Query: 652 DEPAKAGEA 660
             P   G A
Sbjct: 864 GSPGGPGAA 872



 Score = 66.6 bits (161), Expect = 7e-11
 Identities = 63/204 (30%), Positives = 81/204 (39%), Gaps = 31/204 (15%)

Query: 483  GSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETP 542
            G+P  +G P  G  E G   + +G  GP    PG      G  PAGP G +  +    +P
Sbjct: 813  GAPGQNGEP-GGKGERGAPGE-KGEGGP----PGVAGPPGGSGPAGPPGPQGVKGERGSP 866

Query: 543  G-------------PRPAGPAGDEPAESPSETPG-PRPAGPAGDEPAESPSETPGP-SPA 587
            G             P P G  G+     PS +PG   P GPAG+  A       GP   A
Sbjct: 867  GGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDA 926

Query: 588  GPTRDEPAESPSETPG-PRPAGPAGDEPAESPSETPG-PRPAGPAGDEPAESPSETPGPS 645
            G   ++ +      PG P P G AG   A   +  PG P P G  G +  +  S  PG +
Sbjct: 927  GQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGAN 986

Query: 646  -------PAGPTRDEPAKAGEAAE 662
                   P GP +  P  AG A E
Sbjct: 987  GLSGERGPPGP-QGLPGLAGTAGE 1009



 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 72/249 (28%), Positives = 86/249 (34%), Gaps = 54/249 (21%)

Query: 470 AVASGGAQTLALAGSPAPSGH-----PKAGHSENGVE--EDTEGRTGPKEGTPGSPSET- 521
           A A+G       AG P  +G      P+    E G+      +G  G K+G+PG P    
Sbjct: 419 AGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDG-KDGSPGEPGANG 477

Query: 522 -PGPS----------PAGPAGDEPAESPS-ETPGPRPAGPAG--DEPAES---------- 557
            PG +          PAGP G    + P+ E   P PAGP G   EP             
Sbjct: 478 LPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRG 537

Query: 558 -PSETPGPRPAGPAGDEPAESPSETPG-PSPAGPTRDEPAESPSETP------------- 602
            P    GP   G  G   ++  S  PG P P+GP R +P       P             
Sbjct: 538 MPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGP-RGQPGVMGFPGPKGNDGAPGKNGER 596

Query: 603 ----GPRPAGPAGDEPAESPSETPGPR-PAGPAGDEPAESPSETPGPSPAGPTRDEPAKA 657
               GP P GP G      P   PGP  P G  GD     P    G    G    E  K 
Sbjct: 597 GGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKP 656

Query: 658 GEAAELQDA 666
           GE     DA
Sbjct: 657 GEPGPKGDA 665



 Score = 64.3 bits (155), Expect = 3e-10
 Identities = 68/235 (28%), Positives = 81/235 (34%), Gaps = 53/235 (22%)

Query: 464 GAGDSAAVASGGAQTLALA-GSPAPSGHPKAGHSENGVEE----DTEGRTGP-------- 510
           G G+       GA  L  A G P P+G   A     G  E      +G  GP        
Sbjct: 394 GKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAG 453

Query: 511 ------------KEGTPGSPSETPGPSPAGPAGDEPAESPSETPG-PRPAGPAGDEPAES 557
                       K+G+PG P     P  AG  G      P+   G P   GPAG+  A  
Sbjct: 454 IPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPG 513

Query: 558 PSETPGPRPAGPAGDEPAESPSETPG-----PSPAGPTRD---EPAESPSETPGPRPAGP 609
           P+   GPR  G AG+   +     PG      SP GP  D    P  S  E+  P P GP
Sbjct: 514 PA---GPR--GAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGP 568

Query: 610 AGDEPAESPSETPGPR--------------PAGPAGDEPAESPSETPGPSPAGPT 650
           +G          PGP+              P GP    P     ET    P GPT
Sbjct: 569 SGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPT 623



 Score = 63.5 bits (153), Expect = 6e-10
 Identities = 102/389 (26%), Positives = 129/389 (33%), Gaps = 67/389 (17%)

Query: 314  GSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGEDR 373
            GSPG    +    G        K G R   GP      P  AG      GD+  G     
Sbjct: 735  GSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIG---PPGPAG----QPGDKGEGGAPGL 787

Query: 374  PEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGG 433
            P    P+ S   + E          PGP         A    G    +G      ++  G
Sbjct: 788  PGIAGPRGSPGERGETG-------PPGPAGFPG----APGQNGEPGGKGERGAPGEKGEG 836

Query: 434  QDPGEAVQPCRQ-PLGARVADKVRKRRKVDEGAGDSAAVASGGAQ----TLALAGSPAPS 488
              PG A  P    P G      V+  R    G G +    + G      +    G P PS
Sbjct: 837  GPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPS 896

Query: 489  GHP----KAGHSENGVEEDTEGRTGPK--------EGTPGSPSETPGPSPAGPAGDEPAE 536
            G P      G + N     + G +GPK        +G+PG+      P P G AG   A 
Sbjct: 897  GSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGAR 956

Query: 537  SPSETPG-PRPAGPAGDEPAESPSETPGPR-------PAGPAG--------DEPAES--- 577
              +  PG P P G  G +  +  S  PG         P GP G         EP      
Sbjct: 957  GLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNP 1016

Query: 578  -----PSETPGPSPAGPTRDEPAESPSETPG-PRPAGPAGDEPAESPSETPGPRPAGPAG 631
                 P     P   G   +  +      PG P P GP G  PA    +     PAGPAG
Sbjct: 1017 GSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVG--PAGKSGDRGESGPAGPAG 1074

Query: 632  DEPAESPSETPG-PSPAGPTRDEPAKAGE 659
               A  P+ + G P P GP R +  + GE
Sbjct: 1075 ---APGPAGSRGAPGPQGP-RGDKGETGE 1099



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 72/251 (28%), Positives = 80/251 (31%), Gaps = 78/251 (31%)

Query: 467 DSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSP 526
           DS  V SG A    LAG P P+G P              G  GP  GT G P     P  
Sbjct: 156 DSYDVKSGVAVG-GLAGYPGPAGPP--------------GPPGPP-GTSGHPGSPGSPGY 199

Query: 527 AGPAGDEPAESPSETPGPR----PAGPAGDEPAESPSETPGPRPA-------GPAG---- 571
            GP G+     PS  PGP     P+GPAG +        PG R         GPAG    
Sbjct: 200 QGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGF 259

Query: 572 -------------DEPAES-----------PSETPGPSPAGPTRDEPAESPSETPG-PRP 606
                         E  E+           P E   P P GP R  P E     PG P  
Sbjct: 260 PGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGP-RGAPGERGR--PGLPGA 316

Query: 607 AGPAGDEPAESPSETPGPR-------------------PAGPAGDEPAESPSETPGPSPA 647
           AG  G++ A      PGP                    PAG  G   A      PGP   
Sbjct: 317 AGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGH 376

Query: 648 GPTRDEPAKAG 658
              +  P   G
Sbjct: 377 AGAQGPPGPPG 387



 Score = 57.4 bits (137), Expect = 4e-08
 Identities = 62/204 (30%), Positives = 76/204 (37%), Gaps = 30/204 (14%)

Query: 481 LAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSE 540
           + G P   GH +     NG + +T G  G K G  G P E   P P GP G   A     
Sbjct: 256 IPGFPGMKGH-RGFDGRNGEKGET-GAPGLK-GENGLPGENGAPGPMGPRG---APGERG 309

Query: 541 TPG-PRPAGPAGDEPAESPSETPGPR-PAGPAGDEPAES------PSETPGPSPAGPTRD 592
            PG P  AG  G++ A      PGP  P G AG   +        P+ +PG + A   R 
Sbjct: 310 RPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRG 369

Query: 593 EP-------AESPSETPGPRPAGPAGDEPAESPSETPGPR-------PAGPAGDEPAESP 638
           EP       A+ P   PG    G  G +    P+  PG         P GPAG   A   
Sbjct: 370 EPGPQGHAGAQGPPGPPGIN--GSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGL 427

Query: 639 SETPGPSPAGPTRDEPAKAGEAAE 662
               G       + EP   GE  E
Sbjct: 428 RGGAGEPGKNGAKGEPGPRGERGE 451



 Score = 53.1 bits (126), Expect = 8e-07
 Identities = 50/178 (28%), Positives = 59/178 (33%), Gaps = 22/178 (12%)

Query: 505 EGRTGPK--EGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETP 562
           +G  GPK   G PG P     P   G  G   +  P       P GP    P     +  
Sbjct: 102 QGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVK 161

Query: 563 G----------PRPAGPAGDEPAESPSETPG----PSPAGPTRDEPAESPSETPGP---- 604
                      P PAGP G       S  PG    P   GP  +     PS  PGP    
Sbjct: 162 SGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAI 221

Query: 605 RPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAE 662
            P+GPAG +        PG R  G  G    + P+  PG       R    + GE  E
Sbjct: 222 GPSGPAGKDGESGRPGRPGER--GLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGE 277


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 73.2 bits (178), Expect = 8e-13
 Identities = 99/379 (26%), Positives = 135/379 (35%), Gaps = 54/379 (14%)

Query: 343  EGPQPR--SVEPQDAGPLERSQGDEAGGHGEDRP-----EPLSPKESK---KRKLELS-R 391
            + P P   SV PQ   P  +      G  G D P      P+SP E+    +  L     
Sbjct: 792  DSPSPLGVSVSPQTKRPPTKK-----GSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGS 846

Query: 392  REQP-----PTEPGPQSASEVEKIA-LNLEGCALSQGSLRT-GTQEVGGQDPGEAVQ-PC 443
            ++ P     PT P P+ A     +  L+ +G  L      T     +     G A   P 
Sbjct: 847  KDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPK 906

Query: 444  RQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEED 503
            + P  +  +   +K R      G  A+ +  GA T   A  P+P G P     +      
Sbjct: 907  QAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPP 966

Query: 504  TEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPR--PAGPAGDEPAE--SPS 559
                  PK G P +PS    P+P       P   P+ TP P+  P  PA   P+   SP+
Sbjct: 967  AATPPSPKGG-PATPSPKGAPTPPAATPPSPKGGPA-TPSPKGAPTPPAVTPPSPKGSPA 1024

Query: 560  ETPGPRPAG--PAGDEPAE--SPSETPGPS----------------PAGPTRDEPAESPS 599
             TP P+ A   PA   P+   SP+ TP P                 PA P+       P+
Sbjct: 1025 ATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPA 1084

Query: 600  ETPGPRPAGPAGDEPAESP---SETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAK 656
             TP     GPA   P  +P   + TP P P G     P +    TP  +P  P       
Sbjct: 1085 ATPPSPKGGPATPSPKGAPMPPAATP-PSPKGGLATPPHKGAPTTPAATPPSPKGGLATP 1143

Query: 657  AGEAAELQDAEVESSAKSG 675
              + A    A    S K G
Sbjct: 1144 PPKGAPTTPAATPPSPKGG 1162



 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 95/375 (25%), Positives = 133/375 (35%), Gaps = 71/375 (18%)

Query: 347  PRSVEPQDAGPLERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPG------ 400
            P+    +D+G    +       +  D P PL    S + K       +PPT+ G      
Sbjct: 767  PKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTK-------RPPTKKGSAGPDT 819

Query: 401  ----------PQSASEVEKIALNLEGCALSQGSLRTGT--QEVGGQDP---------GEA 439
                      P  AS + + +L+ +G   S  +  + T     G   P         G  
Sbjct: 820  PIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVT 879

Query: 440  VQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENG 499
            + P   P  + V     K          + A++   +       +PAP G P +      
Sbjct: 880  LPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPAS------ 933

Query: 500  VEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPS 559
                      PK G P  P+ TP     GPA   P  +P+  P   P  P G     SP 
Sbjct: 934  --------PSPK-GAPTPPAATPPSPKGGPATPSPKWAPTP-PAATPPSPKGGPATPSPK 983

Query: 560  ETPGPRPAGPAGDE--PAESPSETPGPSPAGPTRDEPAESPSETPGPRPAG--PAGDEPA 615
              P P  A P   +  PA +PS    P+P   T   P  SP+ TP P+ A   PA   P+
Sbjct: 984  GAPTPPAATPPSPKGGPA-TPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPS 1042

Query: 616  E--SPSETPGPR--PAGPAGDEPA-----ESPSETPGPSPAGPTRDEPAKAGEA------ 660
               SP+ TP P+  P  PA   P+      +PS    P+P   T   P K G A      
Sbjct: 1043 PKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSP-KGGPATPSPKG 1101

Query: 661  AELQDAEVESSAKSG 675
            A +  A    S K G
Sbjct: 1102 APMPPAATPPSPKGG 1116



 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 62/221 (28%), Positives = 80/221 (36%), Gaps = 21/221 (9%)

Query: 466  GDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPS 525
            G  A  +  GA T      P+P G P A           +G + P   TP SP  +P  +
Sbjct: 998  GGPATPSPKGAPTPPAVTPPSPKGSPAA-------TPFPKGASTPPAATPPSPKGSPAAT 1050

Query: 526  PAGPAGDEPAESPSETPGPR--PAGPAGDEPAESPSETPGPRPAGPAGDEPAESP---SE 580
            P  P G  P    +  P P+  PA P+       P+ TP     GPA   P  +P   + 
Sbjct: 1051 PL-PKG-APTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAA 1108

Query: 581  TPGPSPAGPTRDEPAESPSETPGPRPAGPAGD---EPAESPSETPGPRPAGPAGD---EP 634
            TP PSP G     P +    TP   P  P G     P +    TP   P  P G     P
Sbjct: 1109 TP-PSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPP 1167

Query: 635  AESPSETPGPSPAGPTRDEPAKAGEAAELQDAEVESSAKSG 675
             +    TP  +P  P       + + A    A    S K G
Sbjct: 1168 PKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG 1208



 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 91/383 (23%), Positives = 112/383 (29%), Gaps = 58/383 (15%)

Query: 313  EGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGED 372
            +G P  P  + +       P   KGG      P+     P    P  +         G  
Sbjct: 928  KGIPASPSPKGAPTPPAATPPSPKGGPATPS-PKWAPTPPAATPPSPKGGPATPSPKGAP 986

Query: 373  RPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVG 432
             P   +P   K            P  P P+ A     +          +GS        G
Sbjct: 987  TPPAATPPSPKGG----------PATPSPKGAPTPPAVTP-----PSPKGSPAATPFPKG 1031

Query: 433  GQDPGEAVQPCRQPLGARVADKVRKRRKVDEGA------GDSAAVASGGAQTLALAGSPA 486
               P  A  P   P G+  A  + K       A      G  A  +  GA T   A  P+
Sbjct: 1032 ASTPPAATPP--SPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPS 1089

Query: 487  PSGHPKAGHSENGVEEDTEGR---------TGPKEGTPGSPSETPGPSPAGPAGDEPAES 537
            P G P A  S  G                 T P +G P +P+ TP PSP G     P + 
Sbjct: 1090 PKGGP-ATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATP-PSPKGGLATPPPKG 1147

Query: 538  PSETPGPRPAGPAGD---EPAESPSETPGPRPAGPAGDEPAESPSETPG------PSPAG 588
               TP   P  P G     P +    TP   P  P G     SP   P       PSP G
Sbjct: 1148 APTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKG 1207

Query: 589  PTRDEPAESPSETPGPRPAGPAGDEPAESPS---ETPGPRPAGPAGDE-----------P 634
                   +    TP   P  P G     SP     TP   P  P G             P
Sbjct: 1208 GLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPP 1267

Query: 635  AESPSETPGPSPAGPTRDEPAKA 657
            A +P    G     P +  P  A
Sbjct: 1268 AATPPSLKGGLATPPHKGAPNPA 1290



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 96/400 (24%), Positives = 124/400 (31%), Gaps = 45/400 (11%)

Query: 297  PSSLPHPLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAG 356
            P   P P   +     +G P  P  + +       P   KGG      P P+      A 
Sbjct: 936  PKGAPTP-PAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPAT---PSPKGAPTPPAA 991

Query: 357  PLERSQGDEAGGHGEDRPEPL-----SPKESKK-----RKLELSRREQPPTEPGPQSASE 406
                 +G  A    +  P P      SPK S       +         PP+  G  +A+ 
Sbjct: 992  TPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATP 1051

Query: 407  VEKIALNLEGCALSQGSLRTGTQEV-GGQDPGEAVQPCRQPLGARVADK---VRKRRKVD 462
            + K A       L        T  + G   P  A  P  +   A  + K   +       
Sbjct: 1052 LPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPP 1111

Query: 463  EGAGDSAAVASGGAQTLALAGSPAPSGH-----PKAGHSENGVEEDTEG---RTGPKEGT 514
               G  A     GA T   A  P+P G      PK   +       +      T P +G 
Sbjct: 1112 SPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGA 1171

Query: 515  PGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPS---ETPGPRPAGPAG 571
            P +P+ TP PSP G       +    TP   P  P G     SP     TP   P  P G
Sbjct: 1172 PTTPAATP-PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKG 1230

Query: 572  DEPAESPS---ETPGPSPAGPTRDEPAESPSETPGPRPAGPAG---------DEPAESPS 619
                 SP     TP  +P  P        P   P P  A P            + A +P+
Sbjct: 1231 GLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPA 1290

Query: 620  ETPGPRP-AGPAGDEP--AESPSETPGPSPAGPTRDEPAK 656
                P P  GPA   P  A +P     PSP G     P K
Sbjct: 1291 VVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPK 1330



 Score = 64.3 bits (155), Expect = 3e-10
 Identities = 53/185 (28%), Positives = 66/185 (35%), Gaps = 20/185 (10%)

Query: 484  SPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPG 543
            +P+P G P    +     +       PK G P +P+ TP PSP G       +    TP 
Sbjct: 1188 TPSPKGAPTTPAATPPSPKGGLATPSPK-GAPTTPAATP-PSPKGGLATPSPKGAPTTPA 1245

Query: 544  PRPAGPAGDEPAESPSETPGPRPAGPAG---------DEPAESPSETPGPSPAGPTRDEP 594
              P  P G      P   P P  A P            + A +P+    PSP G     P
Sbjct: 1246 ATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSP 1305

Query: 595  ---AESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDE--PAESPSETPGP----S 645
               A +P     P P G  G  P +     P   P  P G    PA +PS   GP    S
Sbjct: 1306 PKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSS 1365

Query: 646  PAGPT 650
              GPT
Sbjct: 1366 KEGPT 1370



 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 66/225 (29%), Positives = 79/225 (35%), Gaps = 60/225 (26%)

Query: 466  GDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETP--- 522
            G  A  +  GA T   A  P+P G P                T P +G P  P+ TP   
Sbjct: 1230 GGLATPSPKGAPTTPAATPPSPKGGPA---------------TPPPKGAPTPPAATPPSL 1274

Query: 523  -----------GPSPA---------GPAGDEP--AESPSETPGPRPAGPAGDEPAESPSE 560
                        P+PA         GPA   P  A +P     P P G  G  P +    
Sbjct: 1275 KGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPT 1334

Query: 561  TPGPRPAGPAGDE--PAESPSETPGP----SPAGPTRDEPAESPSETPGPR------PAG 608
             P   P  P G    PA +PS   GP    S  GPT   PA +PS   GP         G
Sbjct: 1335 PPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPT--PPAATPSHKGGPAMTPPSPKRG 1392

Query: 609  PAGDEPAESPSE------TPGPRPAGPAGDEPAESPSETPGPSPA 647
            PA   P   P+       +P   PA P   E A +PS+     PA
Sbjct: 1393 PAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPA 1437



 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 69/216 (31%), Positives = 82/216 (37%), Gaps = 45/216 (20%)

Query: 466  GDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPS 525
            G  A     GA T   A  P+P G P                T P +G P  P+ TP PS
Sbjct: 1299 GGPATSPPKGAPTPPAATPPSPKGSPG---------------TPPPKGAPTPPAVTP-PS 1342

Query: 526  PAGPAGDEPAESPSETPGPR-PAGPAGDEP-AESPSETPGPR------PAGPAGDEPAES 577
            P G     PA +PS   GP  P+   G  P A +PS   GP         GPA   P   
Sbjct: 1343 PKGTP-TLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGD 1401

Query: 578  PSE------TPGPSPAGPTRDEPAESPSE--------TPGPRPAGPAGDEPAESPSETPG 623
            P+       +P  +PA P   E A +PS+        TP      PA   P   P+ TP 
Sbjct: 1402 PTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPA-TPS 1460

Query: 624  PR--PAGPAGDEPAESPSETPGPSPAGPTRDEPAKA 657
             +  P  PA   P  SP E P P     T   P KA
Sbjct: 1461 SKGDPTLPAVTPP--SPKEPPAPKQVA-TSSSPKKA 1493



 Score = 59.7 bits (143), Expect = 9e-09
 Identities = 54/195 (27%), Positives = 68/195 (34%), Gaps = 13/195 (6%)

Query: 466  GDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEG----TPGSPSET 521
            G  A  +  GA T   A  P+P G       +            PK G    +P     T
Sbjct: 1184 GGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTT 1243

Query: 522  PGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPA-ESPSETPGPRPAGPAGDEPAESPSE 580
            P  +P  P G      P   P P  A P   +    +P     P PA      P   P+ 
Sbjct: 1244 PAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPAT 1303

Query: 581  TP---GPSPAGPTRDEPAESPSETPGPR--PAGPAGDEPAESPSETPGPRPAGPAGDEPA 635
            +P    P+P   T   P  SP  TP P+  P  PA   P  SP  TP      P+     
Sbjct: 1304 SPPKGAPTPPAATPPSPKGSPG-TPPPKGAPTPPAVTPP--SPKGTPTLPATTPSSKGGP 1360

Query: 636  ESPSETPGPSPAGPT 650
             +PS   GP+P   T
Sbjct: 1361 TTPSSKEGPTPPAAT 1375



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 100/430 (23%), Positives = 142/430 (33%), Gaps = 61/430 (14%)

Query: 297  PSSLPHPLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKG------------GGRVD-- 342
            P   P P   +     +GSPG P  + +       P   KG            GG     
Sbjct: 1306 PKGAPTP-PAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPS 1364

Query: 343  --EGPQPRSVEPQDAGPLERSQGDEAGGHGEDRP--EPLSPKESKKRKLELSRREQPPTE 398
              EGP P +  P   G    +      G     P  +P SP       + LS ++ P T 
Sbjct: 1365 SKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAV-----IPLSPKKAPATP 1419

Query: 399  PGPQSASEVEKIALNLEGCALSQGSLR----TGTQEVGGQDP---GEAVQPCRQPLGARV 451
               + A+   K   +L   A++  SL+    T   + G   P   G+   P   P   + 
Sbjct: 1420 VTREGAATPSKG--DLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKE 1477

Query: 452  ADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPK 511
                ++           A  A  GA TL      +P   P    S       T      K
Sbjct: 1478 PPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKK 1537

Query: 512  EGTPGSPSETPGPSPAGPAGDEPAESPS-ETPGPRPAGPAGDEPAESPSETPGPRPAGPA 570
              TP + +      P       P ++P+  TP   PA P+  E +  P+ TP      P+
Sbjct: 1538 --TPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPS 1595

Query: 571  GDE-------PAESPSETPGP---SPAGPTRDEPAESPSETPGPRPAGPAG--DEP---- 614
              E        + SP E P P   +P  P +     +P  TP   P  P+   D P    
Sbjct: 1596 PKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPA 1655

Query: 615  -------AESPSETPG-PRPAGP-AGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQD 665
                   A  P  + G P   GP A  E   +P+    P    PTR  P     +A    
Sbjct: 1656 SVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPP 1715

Query: 666  AEVESSAKSG 675
               + SAK+G
Sbjct: 1716 ICPDPSAKNG 1725



 Score = 29.6 bits (65), Expect = 9.5
 Identities = 36/148 (24%), Positives = 46/148 (31%), Gaps = 21/148 (14%)

Query: 510 PKEGTPGSPS-ETPGPSPAGPAGDEPAESPSET------PGPRPAGPAGDEPAESPSETP 562
           P E T   P+ E   P P       P  S          PGP    P    P + P    
Sbjct: 2   PGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAA 61

Query: 563 GPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETP 622
                 P+    A +P E P P  +  T               P G A + P   P+   
Sbjct: 62  NQASPFPSPSTIASTPLEVPFPQSSSGT-------------ALPLGTAPEAPTFLPNLIG 108

Query: 623 GP-RPAGPAGDEPAESPSETPGPSPAGP 649
            P  PA  A   P  +P+    PS + P
Sbjct: 109 PPISPAALALASPMIAPTLKGTPSSSAP 136


>gi|169211436 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 280

 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 48/162 (29%), Positives = 71/162 (43%), Gaps = 4/162 (2%)

Query: 485 PAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGP 544
           P  SG  + G+  + V E T G  GP+E   G+P+ TP   P     + P  +P  TP  
Sbjct: 23  PGESGG-RTGNWVSSVGEMT-GPYGPRE--MGTPTLTPSSPPTLTPSNTPTLTPCSTPTL 78

Query: 545 RPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGP 604
            P       P+ +P+ TP   P       P  +PS TP  +P+      P+ +P+ TP  
Sbjct: 79  TPCSTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSS 138

Query: 605 RPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSP 646
            P       P  +PS TP   P+      P+ +P+ TP  +P
Sbjct: 139 TPTLTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTP 180



 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 42/135 (31%), Positives = 60/135 (44%), Gaps = 5/135 (3%)

Query: 514 TPGS-PSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGD 572
           TP S P+ T   +P       P  +PS TP   P+      P+ +P+ TP  RP      
Sbjct: 135 TPSSTPTLTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSS 194

Query: 573 EPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGD 632
            P  +PS TP  +P+      P  +PS TP   P+      P+ +P+ TP  RP      
Sbjct: 195 TPTLTPSSTPTLTPSST----PTLTPSNTPTLIPSSTPTLTPSSTPTLTPSSRPTLTRSS 250

Query: 633 EPAESPSETPGPSPA 647
            P  +PS TP  +P+
Sbjct: 251 TPTLTPSSTPTLTPS 265



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 39/134 (29%), Positives = 58/134 (43%), Gaps = 1/134 (0%)

Query: 514 TPGS-PSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGD 572
           TP S P+ TP  +P       P  +PS TP   P+      P+ +P+ T    P      
Sbjct: 95  TPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTRSSTPTLTPSS 154

Query: 573 EPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGD 632
            P  +PS TP  +P+      P+ +P+ TP  RP       P  +PS TP   P+     
Sbjct: 155 TPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTL 214

Query: 633 EPAESPSETPGPSP 646
            P+ +P+  P  +P
Sbjct: 215 TPSNTPTLIPSSTP 228



 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 37/131 (28%), Positives = 57/131 (43%)

Query: 517 SPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAE 576
           +P  TP  +P+      P+ +P+ TP   P       P  +PS TP   P+      P+ 
Sbjct: 79  TPCSTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSS 138

Query: 577 SPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAE 636
           +P+ T   +P       P  +PS TP   P+      P+ +P+ TP  RP       P  
Sbjct: 139 TPTLTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTL 198

Query: 637 SPSETPGPSPA 647
           +PS TP  +P+
Sbjct: 199 TPSSTPTLTPS 209



 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 45/162 (27%), Positives = 64/162 (39%), Gaps = 6/162 (3%)

Query: 486 APSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPR 545
           A   HP A   E+G      GRTG    + G  +   GP   G     P+  P+ TP   
Sbjct: 14  AAKEHPMAVPGESG------GRTGNWVSSVGEMTGPYGPREMGTPTLTPSSPPTLTPSNT 67

Query: 546 PAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPR 605
           P       P  +P  TP   P+      P+ +P+ TP  +P       P  +PS TP   
Sbjct: 68  PTLTPCSTPTLTPCSTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLT 127

Query: 606 PAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPA 647
           P+      P+ +P+ T    P       P  +PS TP  +P+
Sbjct: 128 PSSTPTLTPSSTPTLTRSSTPTLTPSSTPTLTPSSTPTLTPS 169



 Score = 64.3 bits (155), Expect = 3e-10
 Identities = 36/130 (27%), Positives = 56/130 (43%)

Query: 517 SPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAE 576
           +P+ TP  +P       P  +PS TP   P+      P+ +P+ TP   P       P  
Sbjct: 91  TPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTRSSTPTL 150

Query: 577 SPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAE 636
           +PS TP  +P+      P+ +P+ TP   P       P  + S TP   P+      P+ 
Sbjct: 151 TPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSS 210

Query: 637 SPSETPGPSP 646
           +P+ TP  +P
Sbjct: 211 TPTLTPSNTP 220



 Score = 63.9 bits (154), Expect = 5e-10
 Identities = 37/131 (28%), Positives = 57/131 (43%)

Query: 517 SPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAE 576
           +PS TP  +P+      P+ +P+ TP   P       P  +PS TP   P+      P+ 
Sbjct: 111 TPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTRSSTPTLTPSSTPTLTPSSTPTLTPSS 170

Query: 577 SPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAE 636
           +P+ TP  +P       P  + S TP   P+      P+ +P+ TP   P       P  
Sbjct: 171 TPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSNTPTLIPSSTPTL 230

Query: 637 SPSETPGPSPA 647
           +PS TP  +P+
Sbjct: 231 TPSSTPTLTPS 241



 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 49/177 (27%), Positives = 70/177 (39%), Gaps = 21/177 (11%)

Query: 476 AQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGS-----PSETPGPSPAGPA 530
           + T  L  S  P+  P +  +       T  R+     TP S     PS TP  +P+   
Sbjct: 113 SSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTRSSTPTLTPSSTPTLTPSSTPTLTPSSTP 172

Query: 531 GDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPT 590
              P+ +P+ TP  RP       P  +PS TP   P+      P  +PS TP   P+   
Sbjct: 173 TLTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSST----PTLTPSNTPTLIPSSTP 228

Query: 591 RDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPA 647
              P+ +P+ TP  RP       P  +PS TP              +PS TP  +P+
Sbjct: 229 TLTPSSTPTLTPSSRPTLTRSSTPTLTPSSTP------------TLTPSSTPTLTPS 273



 Score = 59.7 bits (143), Expect = 9e-09
 Identities = 47/172 (27%), Positives = 67/172 (38%), Gaps = 7/172 (4%)

Query: 478 TLALAGSPA--PSGHPKAGHSENGVEEDTEGRTGPKEGTPG-SPSETPGPSPAGPAGDEP 534
           TL    +P   PS  P    S       +   T     TP  +PS TP  +P+      P
Sbjct: 77  TLTPCSTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTP 136

Query: 535 AESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEP 594
           + +P+ T    P       P  +PS TP   P+      P+ +P+ TP   P       P
Sbjct: 137 SSTPTLTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTP 196

Query: 595 AESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSP 646
             +PS TP   P+      P  +PS TP   P+      P+ +P+ TP   P
Sbjct: 197 TLTPSSTPTLTPS----STPTLTPSNTPTLIPSSTPTLTPSSTPTLTPSSRP 244


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
            sapiens]
          Length = 1487

 Score = 71.2 bits (173), Expect = 3e-12
 Identities = 109/402 (27%), Positives = 142/402 (35%), Gaps = 52/402 (12%)

Query: 301  PHPLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPL-E 359
            P P   + +  E+G+PG P       G    P   +GG   D+G    +  P   GP  E
Sbjct: 644  PGPAGPAGERGEQGAPG-PSGFQGLPGPPGPP--GEGGKPGDQGVPGEAGAPGLVGPRGE 700

Query: 360  RSQGDEAGGHGEDR---PEPLSPKESKKRKLELSRREQPPTEPGPQSASEV--EKIALNL 414
            R    E G  G      P  L            S    PP   GP     +  E+ A  +
Sbjct: 701  RGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGI 760

Query: 415  EGCALSQGSL-RTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVAS 473
             G    +G +   G +   G+D G  +     P G   A+  +        AG + A  +
Sbjct: 761  AGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGA 820

Query: 474  GGAQTLALAGSPAPSGH--PKAGHSENGVEEDTEGRTGPK--EGTPG--SPSETPGPSP- 526
             G +     G P P+G   P     + G + + +G  G K   G PG   PS  PGP   
Sbjct: 821  PGER--GETGPPGPAGFAGPPGADGQPGAKGE-QGEAGQKGDAGAPGPQGPSGAPGPQGP 877

Query: 527  ---AGPAGDEPAESPSETPG-PRPAGPAGDEPAESPSETPGPRPAGPAG-DEPAESPSET 581
                GP G   A+ P    G P  AG  G  P  S      P P GP+G D P  +  ++
Sbjct: 878  TGVTGPKGARGAQGPPGATGFPGAAGRVG--PPGSNGNPGPPGPPGPSGKDGPKGARGDS 935

Query: 582  PGPSPAG-PTRDEPAESPSETPGPRPAGPAGDEPAESPSETPG----------------- 623
              P  AG P    PA  P E   P   GP+G E    P    G                 
Sbjct: 936  GPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFP 995

Query: 624  --PRPAGPAGDEPAESPSETPG-PSPAGPTRDEPAKAGEAAE 662
              P P+G  G + A   S   G P P GP    P   G A E
Sbjct: 996  GLPGPSGEPGKQGAPGASGDRGPPGPVGP----PGLTGPAGE 1033



 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 109/399 (27%), Positives = 131/399 (32%), Gaps = 63/399 (15%)

Query: 312 EEGSPGD--PDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEA-GG 368
           E GSPG   P      +GRT GP  + G    D  P P    P   GP        A G 
Sbjct: 316 ENGSPGPMGPRGLPGERGRT-GPAGAAGARGNDGQPGPAG-PPGPVGPAGGPGFPGAPGA 373

Query: 369 HGEDRPEPLSPKESKKRKLELSRREQP--PTEPGPQSASEVEKIALNLEGCALSQGSLRT 426
            GE  P      E  +       R +P  P  PGP  AS         +G   ++GS   
Sbjct: 374 KGEAGPTGARGPEGAQ-----GPRGEPGTPGSPGPAGASGNP----GTDGIPGAKGS--A 422

Query: 427 GTQEVGGQD--PGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGS 484
           G   + G    PG    P  Q     +  K +         G+       G Q     G 
Sbjct: 423 GAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQ--------TGEPGIAGFKGEQ--GPKGE 472

Query: 485 PAPSGHPKAGHSENGVEEDTEGRTGPKEGTP--GSPSETPGPSPAGPAGDEPAESPSETP 542
           P P+G P+      G EE   G  G   G    G P E   P   G  G +    P   P
Sbjct: 473 PGPAG-PQGAPGPAG-EEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAP 530

Query: 543 GPR-PAGPAGDEPAESPSETPG-------------PRPAGPAGDE-PAESPSETPGPSPA 587
           G R P+G AG + A      PG             P  AGP G   P+ +P E   P P 
Sbjct: 531 GERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPP 590

Query: 588 GPTRDEPAESPSETPGPRPA----GPAGDEPAESP----------SETPGPRPAGPAGDE 633
           GP            PGP+ A    G AG++                ET    P GPAG  
Sbjct: 591 GPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPA 650

Query: 634 PAESPSETPGPSPAGPTRDEPAKAGEAAELQDAEVESSA 672
                   PGPS        P   GE  +  D  V   A
Sbjct: 651 GERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEA 689



 Score = 66.2 bits (160), Expect = 9e-11
 Identities = 77/279 (27%), Positives = 98/279 (35%), Gaps = 58/279 (20%)

Query: 436 PGEAVQPCRQPLGARVADKVRKRRKVDEGA-GDSAAVASGGAQTLALAGSPAPSGHP--K 492
           PGE   P  + L  R  D   + +    GA G+       G Q     G P   G P  K
Sbjct: 551 PGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQ--GARGQPGVMGFPGPK 608

Query: 493 AGHSENGV--EEDTEGRTGPKEGTPGSPSETPGPSPAGPA------GDEPAESPSETPG- 543
             + E G   E+   G  G + G PG   ET    P GPA      G++ A  PS   G 
Sbjct: 609 GANGEPGKAGEKGLPGAPGLR-GLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGL 667

Query: 544 PRPAGPAGD--EPAES--PSETPGPRPAGPAGDEPAESPSETPGPS--------PAGPTR 591
           P P GP G+  +P +   P E   P   GP G+        +PG          P  P  
Sbjct: 668 PGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGT 727

Query: 592 DEP--AESPSETPGPR-------------------PAGPAGDEPAESPSETPGP------ 624
           D P  A  P+  PG +                   P G  GD   + P   PG       
Sbjct: 728 DGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGL 787

Query: 625 ----RPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGE 659
                P GPAG    +     PGP+ +   R  P + GE
Sbjct: 788 TGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGE 826



 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 106/381 (27%), Positives = 133/381 (34%), Gaps = 62/381 (16%)

Query: 309 KVEEEGSPGDPDHEA--STQGRT--CGPEHSKG--GGRVDEG-PQPRSVEPQDAGPLERS 361
           K  E+G PG P         G T   GP    G  G R ++G P P   +     P    
Sbjct: 616 KAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPG 675

Query: 362 QGDEAGGHGEDRPEPLSPKESKKRKLELSRREQP-PTEPGPQSASEVEKIALNLEGCALS 420
           +G + G  G        P E+    L   R E+  P E G   A  ++     L G   +
Sbjct: 676 EGGKPGDQGV-------PGEAGAPGLVGPRGERGFPGERGSPGAQGLQG-PRGLPGTPGT 727

Query: 421 QGSLRTGTQEVGGQDPGEAVQPCRQPL-----GARVADKVRKRRKVDEGAGDSAAVASGG 475
            G    G     G  PG    P  Q +      A +A     R  V E   + A    GG
Sbjct: 728 DGP--KGASGPAGP-PGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGG 784

Query: 476 AQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPK-----EGTPGSPSETPGPSPAGPA 530
                  G P P+G        NG E+   G  GP       G PG   ET  P PAG A
Sbjct: 785 RGLTGPIGPPGPAG-------ANG-EKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFA 836

Query: 531 GDEPAESPSETPGPR-PAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGP 589
           G   A+      G +  AG  GD  A        P P GP+G    + P+   GP  A  
Sbjct: 837 GPPGADGQPGAKGEQGEAGQKGDAGA--------PGPQGPSGAPGPQGPTGVTGPKGARG 888

Query: 590 TRDEPAESPSETPGPRPAGPAGDEPAESPSETPG-PRPAGPAGDEPAESPSETPG----- 643
            +  P      T  P  AG  G   +      PG P P+G  G + A   S  PG     
Sbjct: 889 AQGPPGA----TGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEP 944

Query: 644 --PSPAGPTRDEPAKAGEAAE 662
               PAGP    P + GE  +
Sbjct: 945 GLQGPAGP----PGEKGEPGD 961



 Score = 64.3 bits (155), Expect = 3e-10
 Identities = 77/265 (29%), Positives = 94/265 (35%), Gaps = 43/265 (16%)

Query: 435 DPGEAVQP-CRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQ-TLALAGSPAPSGHPK 492
           +PGE  +P    P+G R       +   D  AG        G        G P   G P 
Sbjct: 226 NPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPG 285

Query: 493 A-GHSENGVEEDTEGRTGPK--EGTPGSPSETPGPSP------------AGPAGDEPAES 537
             GH      +  +G  G    +G  GSP E   P P             GPAG   A  
Sbjct: 286 VKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARG 345

Query: 538 PSETPGPR-PAGPAGDEPAESPSETPGPR----PAGPAGDEPAESPSETPG----PSPAG 588
               PGP  P GP G          PG +    P G  G E A+ P   PG    P PAG
Sbjct: 346 NDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAG 405

Query: 589 PTRD------EPAESPSETPG-------PRPAGPAGDEPAESPSETPGPR-PAGPAGDEP 634
            + +        A+  +  PG       P P GP G + A  P    G     G AG + 
Sbjct: 406 ASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKG 465

Query: 635 AESPSETPGPSPAGPTRDEPAKAGE 659
            + P   PG  PAGP +  P  AGE
Sbjct: 466 EQGPKGEPG--PAGP-QGAPGPAGE 487



 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 65/224 (29%), Positives = 72/224 (32%), Gaps = 34/224 (15%)

Query: 462 DEGAGDSAAVASGGAQTLALAGSPAPSGHP-KAGHSENGVEEDTEGRTGPKEGTPGSPSE 520
           ++  G    V  G    +   G P P+G P   G   N  E    G +GP       P  
Sbjct: 189 EKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPM-----GPRG 243

Query: 521 TPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG-------PRPAGPAGDE 573
            PGP P  P  D  A  P +     P GP G          PG       P   G  G+ 
Sbjct: 244 PPGP-PGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEA 302

Query: 574 PAE-------SPSETPGPSPAGPTRDEPAESPSETPG-----------PRPAGPAGD-EP 614
            A        SP E   P P GP R  P E     P            P PAGP G   P
Sbjct: 303 GAPGVKGESGSPGENGSPGPMGP-RGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGP 361

Query: 615 AESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAG 658
           A  P     P   G AG   A  P    GP     T   P  AG
Sbjct: 362 AGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAG 405



 Score = 59.7 bits (143), Expect = 9e-09
 Identities = 114/413 (27%), Positives = 141/413 (34%), Gaps = 115/413 (27%)

Query: 314  GSPGDPDHEASTQGRTCGPEHSKG--GGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGE 371
            G+PG P           GP    G  G R D GP  R+ EP   GP       E G  G+
Sbjct: 912  GNPGPPGPP--------GPSGKDGPKGARGDSGPPGRAGEPGLQGPA--GPPGEKGEPGD 961

Query: 372  DRPE----PLSPKESKKRK----LELSRREQP-PTEPGPQSASEVEKIALNLEGCALSQG 422
            D P     P  P+    ++    L   R E+  P  PGP S    ++ A    G     G
Sbjct: 962  DGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGP-SGEPGKQGAPGASGDRGPPG 1020

Query: 423  SLRTGTQEVGGQDPGEAVQPCRQ-PLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLAL 481
             +          +PG    P    P G   A  V+  R      G++ AV + GA     
Sbjct: 1021 PVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDR------GETGAVGAPGAP--GP 1072

Query: 482  AGSPAPSGHPKAGHSENGVEEDTEGRTGPK-----------------EGTPGSPSET--- 521
             GSP P+G P     + G E   +G  GP                  +G  G P E    
Sbjct: 1073 PGSPGPAG-PTGKQGDRG-EAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLK 1130

Query: 522  --------------PGPS----PAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG 563
                          PGPS     +GPAG      P     P P GP+G + A      PG
Sbjct: 1131 GHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGP-----PGPVGPSGKDGANG---IPG 1182

Query: 564  P-RPAGPAGDEPAESPSETPG-PSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSET 621
            P  P GP G      P+  PG P P GP              P P GP  D  A      
Sbjct: 1183 PIGPPGPRGRSGETGPAGPPGNPGPPGP--------------PGPPGPGIDMSAF----- 1223

Query: 622  PGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDAEVESSAKS 674
                    AG  P E      GP P    R + A  G      DAEV+++ KS
Sbjct: 1224 --------AGLGPREK-----GPDPLQYMRADQAAGG--LRQHDAEVDATLKS 1261



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 63/217 (29%), Positives = 71/217 (32%), Gaps = 44/217 (20%)

Query: 483 GSPAPSGHPKAGHSENGVEEDT--EGRTGPK-----EGTPGSPSETPGPSPAGPAG---- 531
           G P P G P       G   D   +G  GP+      GTPG+P     P P GP G    
Sbjct: 120 GPPGPQG-PAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGN 178

Query: 532 ---------DEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAE------ 576
                    DE A          P GP G      P+  PGP+       EP E      
Sbjct: 179 FAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGP 238

Query: 577 -SPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPG-------PRPAG 628
             P   PGP P  P  D  A  P +     P GP G          PG       P   G
Sbjct: 239 MGPRGPPGP-PGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDG 297

Query: 629 PAGDEPAE-------SPSETPGPSPAGPTRDEPAKAG 658
             G+  A        SP E   P P GP R  P + G
Sbjct: 298 AKGEAGAPGVKGESGSPGENGSPGPMGP-RGLPGERG 333



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 63/219 (28%), Positives = 73/219 (33%), Gaps = 49/219 (22%)

Query: 506 GRTGPK--EGTPGS------PSETPGPS-PAG---PAGDEPAESPSETPGPR----PAGP 549
           G+ GPK  +G PG       P   PGP  PAG   P GD   +     PGPR      G 
Sbjct: 98  GQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGT 157

Query: 550 AGDEPAESPSETPGP----------------------------RPAGPAGDEPAESPSET 581
            G+     P   PGP                             P GP G      P+  
Sbjct: 158 PGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGA 217

Query: 582 PGPSPAGPTRDEPAESPSETP-GPR-PAGPAGDEPAESPSETPGPR-PAGPAGDEPAESP 638
           PGP        EP E     P GPR P GP G    +  +  PG     GP G + A   
Sbjct: 218 PGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGF 277

Query: 639 SETPGPSPAGPTRDEPAKAGEAAELQDAEVESSAKSGKP 677
             TPG       R  P   G   E     V+   +SG P
Sbjct: 278 PGTPGLPGVKGHRGYPGLDGAKGEAGAPGVK--GESGSP 314


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 1418

 Score = 71.2 bits (173), Expect = 3e-12
 Identities = 109/402 (27%), Positives = 142/402 (35%), Gaps = 52/402 (12%)

Query: 301 PHPLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPL-E 359
           P P   + +  E+G+PG P       G    P   +GG   D+G    +  P   GP  E
Sbjct: 575 PGPAGPAGERGEQGAPG-PSGFQGLPGPPGPP--GEGGKPGDQGVPGEAGAPGLVGPRGE 631

Query: 360 RSQGDEAGGHGEDR---PEPLSPKESKKRKLELSRREQPPTEPGPQSASEV--EKIALNL 414
           R    E G  G      P  L            S    PP   GP     +  E+ A  +
Sbjct: 632 RGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGI 691

Query: 415 EGCALSQGSL-RTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVAS 473
            G    +G +   G +   G+D G  +     P G   A+  +        AG + A  +
Sbjct: 692 AGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGA 751

Query: 474 GGAQTLALAGSPAPSGH--PKAGHSENGVEEDTEGRTGPK--EGTPG--SPSETPGPSP- 526
            G +     G P P+G   P     + G + + +G  G K   G PG   PS  PGP   
Sbjct: 752 PGER--GETGPPGPAGFAGPPGADGQPGAKGE-QGEAGQKGDAGAPGPQGPSGAPGPQGP 808

Query: 527 ---AGPAGDEPAESPSETPG-PRPAGPAGDEPAESPSETPGPRPAGPAG-DEPAESPSET 581
               GP G   A+ P    G P  AG  G  P  S      P P GP+G D P  +  ++
Sbjct: 809 TGVTGPKGARGAQGPPGATGFPGAAGRVG--PPGSNGNPGPPGPPGPSGKDGPKGARGDS 866

Query: 582 PGPSPAG-PTRDEPAESPSETPGPRPAGPAGDEPAESPSETPG----------------- 623
             P  AG P    PA  P E   P   GP+G E    P    G                 
Sbjct: 867 GPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFP 926

Query: 624 --PRPAGPAGDEPAESPSETPG-PSPAGPTRDEPAKAGEAAE 662
             P P+G  G + A   S   G P P GP    P   G A E
Sbjct: 927 GLPGPSGEPGKQGAPGASGDRGPPGPVGP----PGLTGPAGE 964



 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 109/399 (27%), Positives = 131/399 (32%), Gaps = 63/399 (15%)

Query: 312 EEGSPGD--PDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEA-GG 368
           E GSPG   P      +GRT GP  + G    D  P P    P   GP        A G 
Sbjct: 247 ENGSPGPMGPRGLPGERGRT-GPAGAAGARGNDGQPGPAG-PPGPVGPAGGPGFPGAPGA 304

Query: 369 HGEDRPEPLSPKESKKRKLELSRREQP--PTEPGPQSASEVEKIALNLEGCALSQGSLRT 426
            GE  P      E  +       R +P  P  PGP  AS         +G   ++GS   
Sbjct: 305 KGEAGPTGARGPEGAQ-----GPRGEPGTPGSPGPAGASGNP----GTDGIPGAKGS--A 353

Query: 427 GTQEVGGQD--PGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGS 484
           G   + G    PG    P  Q     +  K +         G+       G Q     G 
Sbjct: 354 GAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQ--------TGEPGIAGFKGEQ--GPKGE 403

Query: 485 PAPSGHPKAGHSENGVEEDTEGRTGPKEGTP--GSPSETPGPSPAGPAGDEPAESPSETP 542
           P P+G P+      G EE   G  G   G    G P E   P   G  G +    P   P
Sbjct: 404 PGPAG-PQGAPGPAG-EEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAP 461

Query: 543 GPR-PAGPAGDEPAESPSETPG-------------PRPAGPAGDE-PAESPSETPGPSPA 587
           G R P+G AG + A      PG             P  AGP G   P+ +P E   P P 
Sbjct: 462 GERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPP 521

Query: 588 GPTRDEPAESPSETPGPRPA----GPAGDEPAESP----------SETPGPRPAGPAGDE 633
           GP            PGP+ A    G AG++                ET    P GPAG  
Sbjct: 522 GPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPA 581

Query: 634 PAESPSETPGPSPAGPTRDEPAKAGEAAELQDAEVESSA 672
                   PGPS        P   GE  +  D  V   A
Sbjct: 582 GERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEA 620



 Score = 66.2 bits (160), Expect = 9e-11
 Identities = 77/279 (27%), Positives = 98/279 (35%), Gaps = 58/279 (20%)

Query: 436 PGEAVQPCRQPLGARVADKVRKRRKVDEGA-GDSAAVASGGAQTLALAGSPAPSGHP--K 492
           PGE   P  + L  R  D   + +    GA G+       G Q     G P   G P  K
Sbjct: 482 PGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQ--GARGQPGVMGFPGPK 539

Query: 493 AGHSENGV--EEDTEGRTGPKEGTPGSPSETPGPSPAGPA------GDEPAESPSETPG- 543
             + E G   E+   G  G + G PG   ET    P GPA      G++ A  PS   G 
Sbjct: 540 GANGEPGKAGEKGLPGAPGLR-GLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGL 598

Query: 544 PRPAGPAGD--EPAES--PSETPGPRPAGPAGDEPAESPSETPGPS--------PAGPTR 591
           P P GP G+  +P +   P E   P   GP G+        +PG          P  P  
Sbjct: 599 PGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGT 658

Query: 592 DEP--AESPSETPGPR-------------------PAGPAGDEPAESPSETPGP------ 624
           D P  A  P+  PG +                   P G  GD   + P   PG       
Sbjct: 659 DGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGL 718

Query: 625 ----RPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGE 659
                P GPAG    +     PGP+ +   R  P + GE
Sbjct: 719 TGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGE 757



 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 106/381 (27%), Positives = 133/381 (34%), Gaps = 62/381 (16%)

Query: 309 KVEEEGSPGDPDHEA--STQGRT--CGPEHSKG--GGRVDEG-PQPRSVEPQDAGPLERS 361
           K  E+G PG P         G T   GP    G  G R ++G P P   +     P    
Sbjct: 547 KAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPG 606

Query: 362 QGDEAGGHGEDRPEPLSPKESKKRKLELSRREQP-PTEPGPQSASEVEKIALNLEGCALS 420
           +G + G  G        P E+    L   R E+  P E G   A  ++     L G   +
Sbjct: 607 EGGKPGDQGV-------PGEAGAPGLVGPRGERGFPGERGSPGAQGLQG-PRGLPGTPGT 658

Query: 421 QGSLRTGTQEVGGQDPGEAVQPCRQPL-----GARVADKVRKRRKVDEGAGDSAAVASGG 475
            G    G     G  PG    P  Q +      A +A     R  V E   + A    GG
Sbjct: 659 DGP--KGASGPAGP-PGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGG 715

Query: 476 AQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPK-----EGTPGSPSETPGPSPAGPA 530
                  G P P+G        NG E+   G  GP       G PG   ET  P PAG A
Sbjct: 716 RGLTGPIGPPGPAG-------ANG-EKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFA 767

Query: 531 GDEPAESPSETPGPR-PAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGP 589
           G   A+      G +  AG  GD  A        P P GP+G    + P+   GP  A  
Sbjct: 768 GPPGADGQPGAKGEQGEAGQKGDAGA--------PGPQGPSGAPGPQGPTGVTGPKGARG 819

Query: 590 TRDEPAESPSETPGPRPAGPAGDEPAESPSETPG-PRPAGPAGDEPAESPSETPG----- 643
            +  P      T  P  AG  G   +      PG P P+G  G + A   S  PG     
Sbjct: 820 AQGPPGA----TGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEP 875

Query: 644 --PSPAGPTRDEPAKAGEAAE 662
               PAGP    P + GE  +
Sbjct: 876 GLQGPAGP----PGEKGEPGD 892



 Score = 64.3 bits (155), Expect = 3e-10
 Identities = 77/265 (29%), Positives = 94/265 (35%), Gaps = 43/265 (16%)

Query: 435 DPGEAVQP-CRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQ-TLALAGSPAPSGHPK 492
           +PGE  +P    P+G R       +   D  AG        G        G P   G P 
Sbjct: 157 NPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPG 216

Query: 493 A-GHSENGVEEDTEGRTGPK--EGTPGSPSETPGPSP------------AGPAGDEPAES 537
             GH      +  +G  G    +G  GSP E   P P             GPAG   A  
Sbjct: 217 VKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARG 276

Query: 538 PSETPGPR-PAGPAGDEPAESPSETPGPR----PAGPAGDEPAESPSETPG----PSPAG 588
               PGP  P GP G          PG +    P G  G E A+ P   PG    P PAG
Sbjct: 277 NDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAG 336

Query: 589 PTRD------EPAESPSETPG-------PRPAGPAGDEPAESPSETPGPR-PAGPAGDEP 634
            + +        A+  +  PG       P P GP G + A  P    G     G AG + 
Sbjct: 337 ASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKG 396

Query: 635 AESPSETPGPSPAGPTRDEPAKAGE 659
            + P   PG  PAGP +  P  AGE
Sbjct: 397 EQGPKGEPG--PAGP-QGAPGPAGE 418



 Score = 63.2 bits (152), Expect = 8e-10
 Identities = 91/323 (28%), Positives = 107/323 (33%), Gaps = 45/323 (13%)

Query: 370 GEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSL----R 425
           G+D  +P  PK  K    ++     P   PGPQ  +  E+      G    +G+     R
Sbjct: 25  GQDVRQP-GPKGQKGEPGDIKDIVGPKGPPGPQGPAG-EQGPRGDRGDKGEKGAPGPRGR 82

Query: 426 TGTQEVGGQD--PGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSA-AVASGGAQTLALA 482
            G     G    PG    P    LG   A ++      DE AG +   V  G    +   
Sbjct: 83  DGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGG--FDEKAGGAQLGVMQGPMGPMGPR 140

Query: 483 GSPAPSGHP-KAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSET 541
           G P P+G P   G   N  E    G +GP       P   PGP P  P  D  A  P + 
Sbjct: 141 GPPGPAGAPGPQGFQGNPGEPGEPGVSGPM-----GPRGPPGP-PGKPGDDGEAGKPGKA 194

Query: 542 PGPRPAGPAGDEPAESPSETPG-------PRPAGPAGDEPAE-------SPSETPGPSPA 587
               P GP G          PG       P   G  G+  A        SP E   P P 
Sbjct: 195 GERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPM 254

Query: 588 GPTRDEPAESPSETPG-----------PRPAGPAGD-EPAESPSETPGPRPAGPAGDEPA 635
           GP R  P E     P            P PAGP G   PA  P     P   G AG   A
Sbjct: 255 GP-RGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGA 313

Query: 636 ESPSETPGPSPAGPTRDEPAKAG 658
             P    GP     T   P  AG
Sbjct: 314 RGPEGAQGPRGEPGTPGSPGPAG 336



 Score = 59.7 bits (143), Expect = 9e-09
 Identities = 114/413 (27%), Positives = 141/413 (34%), Gaps = 115/413 (27%)

Query: 314  GSPGDPDHEASTQGRTCGPEHSKG--GGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGE 371
            G+PG P           GP    G  G R D GP  R+ EP   GP       E G  G+
Sbjct: 843  GNPGPPGPP--------GPSGKDGPKGARGDSGPPGRAGEPGLQGPA--GPPGEKGEPGD 892

Query: 372  DRPE----PLSPKESKKRK----LELSRREQP-PTEPGPQSASEVEKIALNLEGCALSQG 422
            D P     P  P+    ++    L   R E+  P  PGP S    ++ A    G     G
Sbjct: 893  DGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGP-SGEPGKQGAPGASGDRGPPG 951

Query: 423  SLRTGTQEVGGQDPGEAVQPCRQ-PLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLAL 481
             +          +PG    P    P G   A  V+  R      G++ AV + GA     
Sbjct: 952  PVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDR------GETGAVGAPGAP--GP 1003

Query: 482  AGSPAPSGHPKAGHSENGVEEDTEGRTGPK-----------------EGTPGSPSET--- 521
             GSP P+G P     + G E   +G  GP                  +G  G P E    
Sbjct: 1004 PGSPGPAG-PTGKQGDRG-EAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLK 1061

Query: 522  --------------PGPS----PAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG 563
                          PGPS     +GPAG      P     P P GP+G + A      PG
Sbjct: 1062 GHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGP-----PGPVGPSGKDGANG---IPG 1113

Query: 564  P-RPAGPAGDEPAESPSETPG-PSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSET 621
            P  P GP G      P+  PG P P GP              P P GP  D  A      
Sbjct: 1114 PIGPPGPRGRSGETGPAGPPGNPGPPGP--------------PGPPGPGIDMSAF----- 1154

Query: 622  PGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDAEVESSAKS 674
                    AG  P E      GP P    R + A  G      DAEV+++ KS
Sbjct: 1155 --------AGLGPREK-----GPDPLQYMRADQAAGG--LRQHDAEVDATLKS 1192


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.132    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,401,440
Number of Sequences: 37866
Number of extensions: 3052959
Number of successful extensions: 72272
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 906
Number of HSP's successfully gapped in prelim test: 2518
Number of HSP's that attempted gapping in prelim test: 18644
Number of HSP's gapped (non-prelim): 21759
length of query: 677
length of database: 18,247,518
effective HSP length: 109
effective length of query: 568
effective length of database: 14,120,124
effective search space: 8020230432
effective search space used: 8020230432
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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