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Search of human proteins with 122937440
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|122937440 multiple EGF-like-domains 9 [Homo sapiens]
(639 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|122937440 multiple EGF-like-domains 9 [Homo sapiens] 1351 0.0
gi|167614504 laminin, beta 1 precursor [Homo sapiens] 199 6e-51
gi|119703755 laminin, beta 2 precursor [Homo sapiens] 192 1e-48
gi|143770880 laminin, beta 4 [Homo sapiens] 174 2e-43
gi|219842266 usherin isoform B [Homo sapiens] 162 7e-40
gi|219842259 usherin isoform A [Homo sapiens] 162 7e-40
gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s... 159 7e-39
gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa... 159 7e-39
gi|38788416 laminin, alpha 1 precursor [Homo sapiens] 155 1e-37
gi|21264602 laminin alpha 5 [Homo sapiens] 142 1e-33
gi|145309326 laminin, gamma 1 precursor [Homo sapiens] 139 8e-33
gi|110611156 laminin, gamma 3 precursor [Homo sapiens] 134 3e-31
gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens] 132 1e-30
gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens] 132 1e-30
gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens] 132 1e-30
gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens] 129 1e-29
gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens] 129 1e-29
gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens] 120 3e-27
gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens] 120 3e-27
gi|62868217 laminin, beta 3 precursor [Homo sapiens] 114 3e-25
gi|62868215 laminin, beta 3 precursor [Homo sapiens] 114 3e-25
gi|189083719 laminin, beta 3 precursor [Homo sapiens] 114 3e-25
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 105 1e-22
gi|14192943 multiple EGF-like-domains 10 [Homo sapiens] 102 1e-21
gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens] 102 1e-21
gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens] 102 1e-21
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] 101 2e-21
gi|122937343 platelet endothelial aggregation receptor 1 [Homo s... 100 5e-21
gi|93204871 netrin 4 [Homo sapiens] 99 2e-20
gi|145701025 multiple EGF-like-domains 8 [Homo sapiens] 94 5e-19
>gi|122937440 multiple EGF-like-domains 9 [Homo sapiens]
Length = 639
Score = 1351 bits (3497), Expect = 0.0
Identities = 639/639 (100%), Positives = 639/639 (100%)
Query: 1 MRSLPSLGGLALLCCAAAAAAAAVASAASAGNVTGGGGAAGQVDASPGPGLRGEPSHPFP 60
MRSLPSLGGLALLCCAAAAAAAAVASAASAGNVTGGGGAAGQVDASPGPGLRGEPSHPFP
Sbjct: 1 MRSLPSLGGLALLCCAAAAAAAAVASAASAGNVTGGGGAAGQVDASPGPGLRGEPSHPFP 60
Query: 61 RATAPTAQAPRTGPPRATVHRPLAATSPAQSPETTPLWATAGPSSTTFQAPLGPSPTTPP 120
RATAPTAQAPRTGPPRATVHRPLAATSPAQSPETTPLWATAGPSSTTFQAPLGPSPTTPP
Sbjct: 61 RATAPTAQAPRTGPPRATVHRPLAATSPAQSPETTPLWATAGPSSTTFQAPLGPSPTTPP 120
Query: 121 AAERTSTTSQAPTRPAPTTLSTTTGPAPTTPVATTVPAPTTPRTPTPDLPSSSNSSVLPT 180
AAERTSTTSQAPTRPAPTTLSTTTGPAPTTPVATTVPAPTTPRTPTPDLPSSSNSSVLPT
Sbjct: 121 AAERTSTTSQAPTRPAPTTLSTTTGPAPTTPVATTVPAPTTPRTPTPDLPSSSNSSVLPT 180
Query: 181 PPATEAPSSPPPGHQWPVAKMPQKYLGKYACESNLKSKYLPLTQPVMNLRVSEAVKTEYV 240
PPATEAPSSPPPGHQWPVAKMPQKYLGKYACESNLKSKYLPLTQPVMNLRVSEAVKTEYV
Sbjct: 181 PPATEAPSSPPPGHQWPVAKMPQKYLGKYACESNLKSKYLPLTQPVMNLRVSEAVKTEYV 240
Query: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALS 300
CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALS
Sbjct: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALS 300
Query: 301 IPCNSSGKCQCKVGVIGSICDRCQDGYYGFSKNGCLPCQCNNRSASCDALTGACLNCQEN 360
IPCNSSGKCQCKVGVIGSICDRCQDGYYGFSKNGCLPCQCNNRSASCDALTGACLNCQEN
Sbjct: 301 IPCNSSGKCQCKVGVIGSICDRCQDGYYGFSKNGCLPCQCNNRSASCDALTGACLNCQEN 360
Query: 361 SKGNHCEECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNC 420
SKGNHCEECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNC
Sbjct: 361 SKGNHCEECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNC 420
Query: 421 NKCENGYYNFDSICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGYVH 480
NKCENGYYNFDSICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGYVH
Sbjct: 421 NKCENGYYNFDSICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGYVH 480
Query: 481 DLEGNCIKKEVILPTPEGSTILVSNASLTTSVPTPVINSTFTPTTLQTIFSVSTSENSTS 540
DLEGNCIKKEVILPTPEGSTILVSNASLTTSVPTPVINSTFTPTTLQTIFSVSTSENSTS
Sbjct: 481 DLEGNCIKKEVILPTPEGSTILVSNASLTTSVPTPVINSTFTPTTLQTIFSVSTSENSTS 540
Query: 541 ALADVSWTQFNIIILTVIIIVVVLLMGFVGAVYMYREYQNRKLNAPFWTIELKEDNISFS 600
ALADVSWTQFNIIILTVIIIVVVLLMGFVGAVYMYREYQNRKLNAPFWTIELKEDNISFS
Sbjct: 541 ALADVSWTQFNIIILTVIIIVVVLLMGFVGAVYMYREYQNRKLNAPFWTIELKEDNISFS 600
Query: 601 SYHDSIPNADVSGLLEDDGNEVAPNGQLTLTTPIHNYKA 639
SYHDSIPNADVSGLLEDDGNEVAPNGQLTLTTPIHNYKA
Sbjct: 601 SYHDSIPNADVSGLLEDDGNEVAPNGQLTLTTPIHNYKA 639
>gi|167614504 laminin, beta 1 precursor [Homo sapiens]
Length = 1786
Score = 199 bits (506), Expect = 6e-51
Identities = 109/297 (36%), Positives = 154/297 (51%), Gaps = 21/297 (7%)
Query: 208 KYACESNLKSKY-LPLTQPVMNLRVSEAV---KTEYVCNCSVVGSLNVNRCNQTTGQCEC 263
+Y C N +S P+T N+ S + +T C C GSL+ + C+ GQC+C
Sbjct: 736 RYRCLENSRSVVKTPMTDVCRNIIFSISALLHQTGLACECDPQGSLS-SVCDPNGGQCQC 794
Query: 264 RPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALSIPCNS-SGKCQCKVGVIGSICDR 322
RP G C C G + SG C+PC+C G+++ CN +G+C C GV CDR
Sbjct: 795 RPNVVGRTCNRCAPGTFGFGPSG-CKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQCDR 853
Query: 323 CQDGYYGFSKNGCLPCQCNNRSASCDALTGACLNCQENSKGNHCEECKEGFYQSP--DAT 380
C G++GF C PCQCN + CD +TG CLNCQ+ + G++CE C G+Y P +
Sbjct: 854 CLPGHWGFPS--CQPCQCNGHADDCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSG 911
Query: 381 KECLRCPCSAVTSTGSCSIKSSELEPECDQ----CKDGYIGPNCNKCENGYYNFDS---- 432
C CPC +G +S +P Q C GYIG C+ C +GY+ S
Sbjct: 912 DHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGG 971
Query: 433 ICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGYVHD-LEGNCIK 488
C+ CQCH ++D P+ C E+G C+ CL++T G C+ C GY D L+ +C K
Sbjct: 972 SCQPCQCHNNID-TTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYYGDALQQDCRK 1027
Score = 116 bits (290), Expect = 7e-26
Identities = 75/237 (31%), Positives = 105/237 (44%), Gaps = 29/237 (12%)
Query: 241 CNC-SVVGSLNVNRCNQTTGQC-ECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGA 298
C C + + + + C++ TG+C +C +G HC+ C+ G+Y + C+ C C+ G
Sbjct: 976 CQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYYGDALQQDCRKCVCNYLGT 1035
Query: 299 LSIPCNSS--------GKCQCKVGVIGSICDRCQDGYYGF-SKNGCLPCQCN---NRSAS 346
+ CN S G+C C VIG CDRC + S GC PC CN + S
Sbjct: 1036 VQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQLASGTGCDPCNCNAAHSFGPS 1095
Query: 347 CDALTGACLNCQENSKGNHCEECKEGFYQSPDATKECLRCPC--------SAVTSTGSCS 398
C+ TG C C G C EC+E F+ PD EC C C STG C
Sbjct: 1096 CNEFTGQC-QCMPGFGGRTCSECQELFWGDPDV--ECRACDCDPRGIETPQCDQSTGQCV 1152
Query: 399 IKSSELEPECDQCKDGYIG--PNCNKCENGYYNFDSICRKC--QCHGHVDPVKTPKI 451
P CD+C GY G P+C C + +D I + + H ++ K KI
Sbjct: 1153 CVEGVEGPRCDKCTRGYSGVFPDCTPCHQCFALWDVIIAELTNRTHRFLEKAKALKI 1209
Score = 98.6 bits (244), Expect = 2e-20
Identities = 57/152 (37%), Positives = 78/152 (51%), Gaps = 19/152 (12%)
Query: 241 CNCSVVGSLNVNRCNQTT--------GQCECRPGYQGLHCETCKEGFY-LNYTSGL-CQP 290
C C GS N C+ T GQC C+ +G HC+ CKEGFY L+ C+
Sbjct: 398 CTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKS 457
Query: 291 CDCSPHGAL--SIPCNS-SGKCQCKVGVIGSICDRCQDGYYGFSK--NGCLPCQCNNRSA 345
C C+P G + PC+S +G C CK V G CD+C ++G S +GC PC C+ A
Sbjct: 458 CACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGA 517
Query: 346 ---SCDALTGACLNCQENSKGNHCEECKEGFY 374
SC A +G C +C+ + G C E + G+Y
Sbjct: 518 LNNSCFAESGQC-SCRPHMIGRQCNEVEPGYY 548
Score = 97.4 bits (241), Expect = 3e-20
Identities = 69/251 (27%), Positives = 101/251 (40%), Gaps = 48/251 (19%)
Query: 279 FYLNYTSGLCQPCDCSPHGALSIPCNS---------SGKCQCKVGVIGSICDRCQDGYY- 328
+Y Y + C C H + P + G C C+ G C+ C D Y+
Sbjct: 259 YYAVYDMVVRGNCFCYGHASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHD 318
Query: 329 -------GFSKNGCLPCQCNNRSASC-----------DALTGACLNCQENSKGNHCEECK 370
G + N C C CN S SC + G C +CQ N+ G +CE+CK
Sbjct: 319 LPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCK 378
Query: 371 EGFYQSPDA----TKECLRCPCSAVTS--TGSC----SIKSSELEPECDQCKDGYIGPNC 420
+YQ P+ C RC C S G C + + +C +CK G +C
Sbjct: 379 PFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQC-RCKLNVEGEHC 437
Query: 421 NKCENGYYNFDSI----CRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLE 476
+ C+ G+Y+ S C+ C C+ + + C E+G C C TG C+ CL
Sbjct: 438 DVCKEGFYDLSSEDPFGCKSCACN-PLGTIPGGNPCDSETGHCY-CKRLVTGQHCDQCLP 495
Query: 477 ---GYVHDLEG 484
G +DL+G
Sbjct: 496 EHWGLSNDLDG 506
Score = 93.2 bits (230), Expect = 7e-19
Identities = 83/346 (23%), Positives = 129/346 (37%), Gaps = 67/346 (19%)
Query: 185 EAPSSPPPGHQWPVAKMPQKYLGKYACESNLKSKYLPLTQPVMNLRVSEAVKTEYVC--- 241
E P SP + + + K++ + NL + + + V+ C
Sbjct: 217 EDPYSPRIQNLLKITNLRIKFVKLHTLGDNLLDSRMEIREKYYYAVYDMVVRGNCFCYGH 276
Query: 242 --NCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFY-------LNYTSGLCQPCD 292
C+ V N G C CR +GL+CE C + ++ S C+ C+
Sbjct: 277 ASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCN 336
Query: 293 CSPHGALSIPCN------------SSGKC-QCKVGVIGSICDRCQDGYYGFSK------N 333
C+ H SI C+ S G C C+ +G C++C+ YY + N
Sbjct: 337 CNEH---SISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPN 393
Query: 334 GCLPCQC----NNRSASCDALT--------GACLNCQENSKGNHCEECKEGFY----QSP 377
C C C + CD+ T G C C+ N +G HC+ CKEGFY + P
Sbjct: 394 FCERCTCDPAGSQNEGICDSYTDFSTGLIAGQC-RCKLNVEGEHCDVCKEGFYDLSSEDP 452
Query: 378 DATKECLRCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGYYNFDSI---C 434
K C P + C ++ CK G +C++C ++ + C
Sbjct: 453 FGCKSCACNPLGTIPGGNPCDSETGHC-----YCKRLVTGQHCDQCLPEHWGLSNDLDGC 507
Query: 435 RKCQCH--GHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGY 478
R C C G ++ C ESG+C +C + G C GY
Sbjct: 508 RPCDCDLGGALN-----NSCFAESGQC-SCRPHMIGRQCNEVEPGY 547
Score = 91.7 bits (226), Expect = 2e-18
Identities = 61/216 (28%), Positives = 95/216 (43%), Gaps = 31/216 (14%)
Query: 238 EYVCNCSVVGSLNVNRCNQTTGQCE-CRPGYQGLHCETCKEGFYLNYTSGL-----CQPC 291
E+ +C ++ + N + G C+ C+ G +CE CK +Y + + C+ C
Sbjct: 339 EHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERC 398
Query: 292 DCSPHGALSIP-CNS---------SGKCQCKVGVIGSICDRCQDGYYGFSKN---GCLPC 338
C P G+ + C+S +G+C+CK+ V G CD C++G+Y S GC C
Sbjct: 399 TCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSC 458
Query: 339 QCNNRSA-----SCDALTGACLNCQENSKGNHCEECKEGFYQSPDATKECLRCPCSAVTS 393
CN CD+ TG C C+ G HC++C + + C C C +
Sbjct: 459 ACNPLGTIPGGNPCDSETGHCY-CKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGA 517
Query: 394 -TGSCSIKSSELEPECDQCKDGYIGPNCNKCENGYY 428
SC +S + C+ IG CN+ E GYY
Sbjct: 518 LNNSCFAESGQCS-----CRPHMIGRQCNEVEPGYY 548
>gi|119703755 laminin, beta 2 precursor [Homo sapiens]
Length = 1798
Score = 192 bits (487), Expect = 1e-48
Identities = 98/250 (39%), Positives = 132/250 (52%), Gaps = 18/250 (7%)
Query: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALS 300
C C+ GSL+ + CN GQC C+PG G C+ C G+Y +G CQ C CS GALS
Sbjct: 783 CQCNPQGSLS-SECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTG-CQACQCSHEGALS 840
Query: 301 IPCN-SSGKCQCKVGVIGSICDRCQDGYYGFSKNGCLPCQCNNRSASCDALTGACLNCQE 359
C +SG+C C+ G G CDRCQ G +GF C PC CN + C+ TGACL C++
Sbjct: 841 SLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFPS--CRPCVCNGHADECNTHTGACLGCRD 898
Query: 360 NSKGNHCEECKEGFYQSPDAT--KECLRCPC-----SAVTSTGSCSIKSSELEPECDQCK 412
++ G HCE C GF+ P +C CPC S SC + C C+
Sbjct: 899 HTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVC-HCR 957
Query: 413 DGYIGPNCNKCENGYYNFDS----ICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTG 468
GY G C C G++ S C+ C+C G++DP+ P C P +G+C+ CLH+T G
Sbjct: 958 AGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNIDPM-DPDACDPHTGQCLRCLHHTEG 1016
Query: 469 FWCENCLEGY 478
C +C G+
Sbjct: 1017 PHCAHCKPGF 1026
Score = 113 bits (282), Expect = 6e-25
Identities = 81/255 (31%), Positives = 114/255 (44%), Gaps = 34/255 (13%)
Query: 250 NVNRCNQTTGQC-ECRPGYQGLHCETCKEGFY----LNYTSGLCQPCDCSP------HGA 298
+ + CN TG C CR G HCE C GF+ L Y G C+PC C H A
Sbjct: 882 HADECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPY-GGQCRPCPCPEGPGSQRHFA 940
Query: 299 LSIPCNSSGK---CQCKVGVIGSICDRCQDGYYGF-SKNG--CLPCQCNNR-----SASC 347
S + + C C+ G G C+ C G++G S+ G C C+C+ +C
Sbjct: 941 TSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDAC 1000
Query: 348 DALTGACLNCQENSKGNHCEECKEGFYQSPDATKECLRCPCSAV-TSTGSC-SIKSSELE 405
D TG CL C +++G HC CK GF+ A + C RC C+ + T+ C S +
Sbjct: 1001 DPHTGQCLRCLHHTEGPHCAHCKPGFH-GQAARQSCHRCTCNLLGTNPQQCPSPDQCHCD 1059
Query: 406 PECDQCK--DGYIGPNCNKCENGYYNFDS--ICRKCQCHGHVDPVKTPKICKPESGECIN 461
P QC GP+C++C ++N S C+ C C H + P C +G+C +
Sbjct: 1060 PSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHGCQPCAC--HPSRARGP-TCNEFTGQC-H 1115
Query: 462 CLHNTTGFWCENCLE 476
C G C C E
Sbjct: 1116 CRAGFGGRTCSECQE 1130
Score = 104 bits (260), Expect = 2e-22
Identities = 68/223 (30%), Positives = 95/223 (42%), Gaps = 23/223 (10%)
Query: 240 VCNCSV-VGSLNVNRCNQTTGQC-ECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHG 297
+C CS + ++ + C+ TGQC C +G HC CK GF+ C C C+ G
Sbjct: 985 LCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSCHRCTCNLLG 1044
Query: 298 ALSIPCNS---------SGKCQCKVGVIGSICDRCQDGYYGF-SKNGCLPCQCNN---RS 344
C S SG+C C V G CDRC ++ S +GC PC C+ R
Sbjct: 1045 TNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHGCQPCACHPSRARG 1104
Query: 345 ASCDALTGACLNCQENSKGNHCEECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKSSEL 404
+C+ TG C +C+ G C EC+E + P +C C C S G + +
Sbjct: 1105 PTCNEFTGQC-HCRAGFGGRTCSECQELHWGDPGL--QCHACDCD---SRGIDTPQCHRF 1158
Query: 405 EPECDQCKDGYIGPNCNKCENGYYNFDSICRKCQ-CHGHVDPV 446
C C+ G G C++C G+ C C C G D V
Sbjct: 1159 TGHCS-CRPGVSGVRCDQCARGFSGIFPACHPCHACFGDWDRV 1200
Score = 103 bits (257), Expect = 5e-22
Identities = 63/204 (30%), Positives = 93/204 (45%), Gaps = 41/204 (20%)
Query: 255 NQTTGQCE-CRPGYQGLHCETCKEGFYLNYTSGL-----CQPCDCSPHGALSIP-CNS-- 305
N + G C+ C+ G HCE C+ FY + T L C+ CDC P G+ C+S
Sbjct: 368 NVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHD 427
Query: 306 -------SGKCQCKVGVIGSICDRCQDGYYGFS---KNGCLPCQCNNR-----SASCDAL 350
SG+C+CK V+G+ C +C+DG++G S + GC CQCN R S CD
Sbjct: 428 DPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPN 487
Query: 351 TGACLNCQENSKGNHCEECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKSSELEPECDQ 410
+G+C C+ G C+ C G + C C C L+P+CD+
Sbjct: 488 SGSCY-CKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDV----------GGALDPQCDE 536
Query: 411 ------CKDGYIGPNCNKCENGYY 428
C+ +G C + + GY+
Sbjct: 537 GTGQCHCRQHMVGRRCEQVQPGYF 560
Score = 100 bits (250), Expect = 3e-21
Identities = 73/254 (28%), Positives = 102/254 (40%), Gaps = 54/254 (21%)
Query: 279 FYLNYTSGLCQPCDCSPHGALSIPCNSS---------GKCQCKVGVIGSICDRCQDGYYG 329
+Y Y + C C H + P + G C CK G C++CQD Y
Sbjct: 271 YYALYELVVRGNCFCYGHASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRD 330
Query: 330 FS--------KNGCLPCQCNNRSASC-----------DALTGACLNCQENSKGNHCEECK 370
+ C C+C+ + SC + G C CQ N+ G HCE C+
Sbjct: 331 LPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCR 390
Query: 371 EGFYQSPDATKE------CLRCPCSAVTST--GSCSIKSSE----LEPECDQCKDGYIGP 418
FY+ P TK+ C C C + S G C + +C +CK+ +G
Sbjct: 391 PFFYRDP--TKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQC-RCKEHVVGT 447
Query: 419 NCNKCENGYYNFDSI----CRKCQCHGH-VDPVKTPKICKPESGECINCLHNTTGFWCEN 473
C +C +G++ CR+CQC+ P TP C P SG C C TG C+
Sbjct: 448 RCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTP--CDPNSGSCY-CKRLVTGRGCDR 504
Query: 474 CLEGY---VHDLEG 484
CL G+ HDL G
Sbjct: 505 CLPGHWGLSHDLLG 518
Score = 93.6 bits (231), Expect = 5e-19
Identities = 59/173 (34%), Positives = 79/173 (45%), Gaps = 25/173 (14%)
Query: 333 NGCLPCQCNNR---SASCDALTGACLNCQENSKGNHCEECKEGFYQSPDATKECLRCPCS 389
NG LPCQCN + S+ C+ G CL C+ G C+ C G+Y C C CS
Sbjct: 778 NGALPCQCNPQGSLSSECNPHGGQCL-CKPGVVGRRCDLCAPGYYGF--GPTGCQACQCS 834
Query: 390 AVTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGYYNFDSICRKCQCHGHVDPVKTP 449
+ S K+S +C C+ G G C++C+ G + F S CR C C+GH D
Sbjct: 835 HEGALSSLCEKTSG---QC-LCRTGAFGLRCDRCQRGQWGFPS-CRPCVCNGHADE---- 885
Query: 450 KICKPESGECINCLHNTTGFWCENCLEGYVHD----LEGNCIKKEVILPTPEG 498
C +G C+ C +T G CE C+ G+ D G C P PEG
Sbjct: 886 --CNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRP----CPCPEG 932
Score = 39.3 bits (90), Expect = 0.011
Identities = 16/40 (40%), Positives = 25/40 (62%), Gaps = 1/40 (2%)
Query: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFY 280
C+C V G+L+ +C++ TGQC CR G CE + G++
Sbjct: 522 CDCDVGGALDP-QCDEGTGQCHCRQHMVGRRCEQVQPGYF 560
>gi|143770880 laminin, beta 4 [Homo sapiens]
Length = 1761
Score = 174 bits (441), Expect = 2e-43
Identities = 90/248 (36%), Positives = 125/248 (50%), Gaps = 16/248 (6%)
Query: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALS 300
C C GS+ + C++ GQC+C+P G C+ C G Y G C PC C P G+
Sbjct: 769 CKCHPQGSVG-SSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHG-CHPCHCHPQGSKD 826
Query: 301 IPCNS-SGKCQCKVGVIGSICDRCQDGYYGFSKNGCLPCQCNNRSASCDALTGACLNCQE 359
C+ +G+C C V G CDRC GY+GF C PC CN + CD TG+C NC
Sbjct: 827 TVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFPS--CHPCPCNRFAELCDPETGSCFNCGG 884
Query: 360 NSKGNHCEECKEGFYQSPDATKECLRCPCSAVTSTG-----SCSIKSSELEPECDQCKDG 414
+ G +CE C +G+Y +P + + C C C S+ SC + C+ C G
Sbjct: 885 FTTGRNCERCIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICN-CLQG 943
Query: 415 YIGPNCNKCENGYYNFDSI----CRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFW 470
Y G C +C G+Y I C+ C C+ ++D V P+ C +GEC+ CLHNT G
Sbjct: 944 YTGTQCGECSTGFYGNPRISGAPCQPCACNNNID-VTDPESCSRVTGECLRCLHNTQGAN 1002
Query: 471 CENCLEGY 478
C+ C G+
Sbjct: 1003 CQLCKPGH 1010
Score = 121 bits (303), Expect = 2e-27
Identities = 88/280 (31%), Positives = 112/280 (40%), Gaps = 49/280 (17%)
Query: 241 CNCSVVGSLNVNRCNQTTGQC-ECRPGYQGLHCETCKEGFYLNYTSGL-CQPCDCSP--- 295
C C+ L C+ TG C C G +CE C +G+Y N +SG C+PC C
Sbjct: 863 CPCNRFAEL----CDPETGSCFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPCLCPDDPS 918
Query: 296 ------HGALSIPCNSSGKCQCKVGVIGSICDRCQDGYYG---FSKNGCLPCQCNNR--- 343
H +S C C G G+ C C G+YG S C PC CNN
Sbjct: 919 SNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDV 978
Query: 344 --SASCDALTGACLNCQENSKGNHCEECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKS 401
SC +TG CL C N++G +C+ CK G Y S + C RC C A +
Sbjct: 979 TDPESCSRVTGECLRCLHNTQGANCQLCKPGHYGSA-LNQTCRRCSCHA------SGVSP 1031
Query: 402 SELEPE-----CD------QCKDGYIGPNCNKCENGYYNF--DSICRKCQCHGHVDP-VK 447
E P CD C G C++C +GY+N C+ C C DP
Sbjct: 1032 MECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGRGCQSCDC----DPRTS 1087
Query: 448 TPKICKPESGECINCLHNTTGFWCENCLEGYVHDLEGNCI 487
C +G+C C G C C E Y D G CI
Sbjct: 1088 QSSHCDQLTGQC-PCKLGYGGKRCSECQENYYGDPPGRCI 1126
Score = 116 bits (290), Expect = 7e-26
Identities = 69/231 (29%), Positives = 101/231 (43%), Gaps = 35/231 (15%)
Query: 228 NLRVSEAVKTEYVCNCSVVGSLNVNRCNQTTGQC-ECRPGYQGLHCETCKEGFYLNYTSG 286
N R+S A CN ++ + C++ TG+C C QG +C+ CK G Y + +
Sbjct: 959 NPRISGAPCQPCACNNNI-DVTDPESCSRVTGECLRCLHNTQGANCQLCKPGHYGSALNQ 1017
Query: 287 LCQPCDCSPHGALSIPCNS----------SGKCQCKVGVIGSICDRCQDGYYGFSKN-GC 335
C+ C C G + C +G C C V G CDRC DGY+ GC
Sbjct: 1018 TCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGRGC 1077
Query: 336 LPCQCNNR---SASCDALTGACLNCQENSKGNHCEECKEGFYQSPDATKECLRCPCSAVT 392
C C+ R S+ CD LTG C C+ G C EC+E +Y P C+ C C+
Sbjct: 1078 QSCDCDPRTSQSSHCDQLTGQC-PCKLGYGGKRCSECQENYYGDPPG--RCIPCDCN--- 1131
Query: 393 STGSCSIKSSELEPECD------QCKDGYIGPNCNKCENGYYNFDSICRKC 437
++ +P CD +C++G G C++C G+ C +C
Sbjct: 1132 -------RAGTQKPICDPDTGMCRCREGVSGQRCDRCARGHSQEFPTCLQC 1175
Score = 109 bits (273), Expect = 7e-24
Identities = 50/137 (36%), Positives = 65/137 (47%), Gaps = 5/137 (3%)
Query: 254 CNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALSIPCNS-SGKCQCK 312
C+ TG C C P GL C+ C +G++ CQ CDC P + S C+ +G+C CK
Sbjct: 1043 CDPVTGACPCLPNVTGLACDRCADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCK 1102
Query: 313 VGVIGSICDRCQDGYYGFSKNGCLPCQCNNRSAS---CDALTGACLNCQENSKGNHCEEC 369
+G G C CQ+ YYG C+PC CN CD TG C C+E G C+ C
Sbjct: 1103 LGYGGKRCSECQENYYGDPPGRCIPCDCNRAGTQKPICDPDTGMC-RCREGVSGQRCDRC 1161
Query: 370 KEGFYQSPDATKECLRC 386
G Q +C C
Sbjct: 1162 ARGHSQEFPTCLQCHLC 1178
Score = 100 bits (248), Expect = 5e-21
Identities = 63/194 (32%), Positives = 90/194 (46%), Gaps = 30/194 (15%)
Query: 259 GQCE-CRPGYQGLHCETCKEGFYLNYTSGL-----CQPCDCSPHGALSIP-CNS------ 305
G CE C+ +G HC+ C+ FY + + C PC+C P G +S C S
Sbjct: 357 GVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHSDPAL 416
Query: 306 ---SGKCQCKVGVIGSICDRCQDGYYGFSKN---GCLPCQCNNRSA----SCDALTGACL 355
+G+C CK V G+ CD+C+ +YG S GC PC CN + +CD TG CL
Sbjct: 417 GSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCL 476
Query: 356 NCQENSKGNHCEECKEGFYQSPDATKECLRCPCS-AVTSTGSCSIKSSELEPECDQCKDG 414
C G HCEEC G++ + C C C + CS K+ + E C+
Sbjct: 477 -CLSYVTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQCE-----CRPH 530
Query: 415 YIGPNCNKCENGYY 428
G +C++ GY+
Sbjct: 531 VTGRSCSEPAPGYF 544
Score = 97.4 bits (241), Expect = 3e-20
Identities = 69/247 (27%), Positives = 103/247 (41%), Gaps = 41/247 (16%)
Query: 267 YQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALSIPCNSSGKCQCKVGVIGSICDRCQDG 326
Y L+ + + N + C+P S P G+C C+ G C+RC+D
Sbjct: 253 YYALYEMIVRGSCFCNGHASECRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERCKDF 312
Query: 327 YYG--------FSKNGCLPCQCNNRSASC--DALT---------GACLNCQENSKGNHCE 367
+ N C C CN+ S+ C D T G C +CQ N++G HC+
Sbjct: 313 FQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCD 372
Query: 368 ECKEGFYQSPDAT----KECLRCPC--SAVTSTGSCSIKS----SELEPECDQCKDGYIG 417
C+ FY+ P T C+ C C S G C S + +C CK+ G
Sbjct: 373 RCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQC-LCKENVEG 431
Query: 418 PNCNKCENGYYNFDSI----CRKCQCH--GHVDPVKTPKICKPESGECINCLHNTTGFWC 471
C++C+ +Y + C+ C C+ G + P T C ++G+C+ CL TG C
Sbjct: 432 AKCDQCKPNHYGLSATDPLGCQPCDCNPLGSL-PFLT---CDVDTGQCL-CLSYVTGAHC 486
Query: 472 ENCLEGY 478
E C GY
Sbjct: 487 EECTVGY 493
Score = 87.4 bits (215), Expect = 4e-17
Identities = 64/257 (24%), Positives = 104/257 (40%), Gaps = 43/257 (16%)
Query: 259 GQCECRPGYQGLHCETCKEGFY-------LNYTSGLCQPCDCSPHGA---------LSIP 302
GQC C+ G +CE CK+ F + C+ C C+ H + L+
Sbjct: 293 GQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASG 352
Query: 303 CNSSGKCQ-CKVGVIGSICDRCQDGYYG------FSKNGCLPCQC------------NNR 343
S G C+ C+ G CDRC+ +Y C+PC+C ++
Sbjct: 353 GLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHS 412
Query: 344 SASCDALTGACLNCQENSKGNHCEECKEGFY-QSPDATKECLRCPCSAVTSTGSCSIKSS 402
+ ++ G CL C+EN +G C++CK Y S C C C+ + GS +
Sbjct: 413 DPALGSVAGQCL-CKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPL---GSLPFLTC 468
Query: 403 ELEPECDQCKDGYIGPNCNKCENGYYNFDSICRKCQ-CHGHVDPVKTPKICKPESGECIN 461
+++ C G +C +C GY+ + C C + + +C P++G+C
Sbjct: 469 DVDTGQCLCLSYVTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYS-NVCSPKNGQC-E 526
Query: 462 CLHNTTGFWCENCLEGY 478
C + TG C GY
Sbjct: 527 CRPHVTGRSCSEPAPGY 543
Score = 72.0 bits (175), Expect = 2e-12
Identities = 36/91 (39%), Positives = 49/91 (53%), Gaps = 4/91 (4%)
Query: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFY--LNYTSGLCQPCDCSPHGA 298
C+C+ +GSL C+ TGQC C G HCE C G++ N+ G C PCDC GA
Sbjct: 455 CDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLGNHLHG-CSPCDCDIGGA 513
Query: 299 LSIPCN-SSGKCQCKVGVIGSICDRCQDGYY 328
S C+ +G+C+C+ V G C GY+
Sbjct: 514 YSNVCSPKNGQCECRPHVTGRSCSEPAPGYF 544
Score = 42.4 bits (98), Expect = 0.001
Identities = 23/85 (27%), Positives = 34/85 (40%), Gaps = 14/85 (16%)
Query: 411 CKDGYIGPNCNKCENGYYNF---------DSICRKCQCHGHVDPVKTPKICKPESGE--- 458
C+ GPNC +C++ + + D+ CR C C+ H SG
Sbjct: 297 CQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGGLSG 356
Query: 459 --CINCLHNTTGFWCENCLEGYVHD 481
C +C HNT G C+ C + D
Sbjct: 357 GVCEDCQHNTEGQHCDRCRPLFYRD 381
>gi|219842266 usherin isoform B [Homo sapiens]
Length = 5202
Score = 162 bits (411), Expect = 7e-40
Identities = 105/314 (33%), Positives = 154/314 (49%), Gaps = 24/314 (7%)
Query: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEG-FYLNY-TSGLCQPCDCSPHGA 298
C+C GSL CN TGQC C+P +G C C EG FYL S LC PC+C G
Sbjct: 795 CDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGT 854
Query: 299 L--SIPCN-SSGKCQCKVGVIGSICDRCQDGYYGFSKNG---CLPCQCNN----RSASCD 348
+ S+ CN S+G+C CK+GV G C++C+ Y + + C C+C++ CD
Sbjct: 855 INGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICD 914
Query: 349 ALTGACLNCQENSKGNHCEECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKSSELEPEC 408
++G CL C N +G C +C+ GFY SP CL C C +TG+ + + L +C
Sbjct: 915 PISGQCL-CVPNRQGRRCNQCQPGFYISPGNATGCLPCSCH---TTGAVNHICNSLTGQC 970
Query: 409 DQCKDGYI-GPNCNKCENGYYNFDSICRKCQ-CHGHVDPVKTPKICKPESGECINCLHNT 466
C+D I G C++C++ Y+ FD +CQ C+ H+ + C +G+C C
Sbjct: 971 -VCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALN-ETCHLVTGQCF-CKQFV 1027
Query: 467 TGFWCENCLEGYVH-DLEG--NCIKKEVILPTPEGSTILVSNASLTTSVPTPVINSTFTP 523
TG C+ C+ H D+ C K P P G S +L+ S P T
Sbjct: 1028 TGSKCDACVPSASHLDVNNLLGCSKTPFQQPPPRGQVQSSSAINLSWSPPDSPNAHWLTY 1087
Query: 524 TTLQTIFSVSTSEN 537
+ L+ F + T+E+
Sbjct: 1088 SLLRDGFEIYTTED 1101
Score = 152 bits (384), Expect = 9e-37
Identities = 87/253 (34%), Positives = 131/253 (51%), Gaps = 23/253 (9%)
Query: 241 CNCSVVGSLNVN-RCNQTTGQCECRPGYQGLHCETCKEGFYL--NYTSGLCQPCDCSPHG 297
CNC+ G+++ + C+Q +GQC+C+ GL C+ C GF ++ C+PC C+ HG
Sbjct: 694 CNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHG 753
Query: 298 ALSIPCN-SSGKCQCKVGVIGSICDRCQDGYYGFSKNGCLPCQCNNRSA----SCDALTG 352
+++ CN SG+C+CK G CD C++ +YG C C C+ + C+A TG
Sbjct: 754 SVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTG 813
Query: 353 ACLNCQENSKGNHCEECKEG-FYQSPDATKECLRCPCSAVTSTGSCSIKSSELEPECDQC 411
C+ C+ N +G C +C EG FY + + CL C C T T + S+ ++ +C C
Sbjct: 814 QCI-CKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDK-TGTINGSLLCNKSTGQC-PC 870
Query: 412 KDGYIGPNCNKCENGYYNFD----SICRKCQCHGHVDPVKT--PKICKPESGECINCLHN 465
K G G CN+CE YN C+ C+C D + T IC P SG+C+ C+ N
Sbjct: 871 KLGVTGLRCNQCEPHRYNLTIDNFQHCQMCEC----DSLGTLPGTICDPISGQCL-CVPN 925
Query: 466 TTGFWCENCLEGY 478
G C C G+
Sbjct: 926 RQGRRCNQCQPGF 938
Score = 134 bits (338), Expect = 2e-31
Identities = 89/285 (31%), Positives = 126/285 (44%), Gaps = 31/285 (10%)
Query: 211 CESNLKSKYLPLTQPVMNLRVS---EAVKTEYVCNCSVVGSLNVN-RCNQTTGQCECRPG 266
CE N + L + +V A+ C+C VG+ N + C+Q GQC C+
Sbjct: 608 CEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRH 667
Query: 267 YQGLHCETCKEGFY--LNYTSGLCQPCDCSPHGAL--SIPCN-SSGKCQCKVGVIGSICD 321
G C C+ GFY C PC+C+ G + I C+ +SG+C+CK VIG CD
Sbjct: 668 VSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCD 727
Query: 322 RCQDGY---YGFSKNGCLPCQCN---NRSASCDALTGACLNCQENSKGNHCEECKEGFYQ 375
C G+ F+ GC PCQCN + + C+ +G C C++ +KG C+ C+E FY
Sbjct: 728 HCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQC-ECKKEAKGLQCDTCRENFY- 785
Query: 376 SPDATKECLRCPCSAVTSTGS--CSIKSSELEPECDQCKDGYIGPNCNKCENGYY----N 429
D T C C C S C+ K+ + CK G CNKC G + N
Sbjct: 786 GLDVT-NCKACDCDTAGSLPGTVCNAKTGQC-----ICKPNVEGRQCNKCLEGNFYLRQN 839
Query: 430 FDSICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENC 474
+C C C + +C +G+C C TG C C
Sbjct: 840 NSFLCLPCNC-DKTGTINGSLLCNKSTGQC-PCKLGVTGLRCNQC 882
Score = 112 bits (280), Expect = 1e-24
Identities = 76/247 (30%), Positives = 109/247 (44%), Gaps = 29/247 (11%)
Query: 259 GQCE-CRPGYQGLHCETCKEGFYLNYTS-----GLCQPCDCSPHGAL--SIPCNS-SGKC 309
G C+ C G +CE CK+ F+ + +C+PCDC G SI C+ G+C
Sbjct: 603 GVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQC 662
Query: 310 QCKVGVIGSICDRCQDGYYGFSK---NGCLPCQCNNRSA-----SCDALTGACLNCQENS 361
CK V G C++CQ+G+Y + +GC PC CN +C +G C C+ N
Sbjct: 663 NCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQC-KCKANV 721
Query: 362 KGNHCEECKEGF-YQSPDATKECLRCPCSAVTSTGS-CSIKSSELEPECDQCKDGYIGPN 419
G C+ C GF + C C C+ S C+ S + E CK G
Sbjct: 722 IGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCE-----CKKEAKGLQ 776
Query: 420 CNKCENGYYNFD-SICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGY 478
C+ C +Y D + C+ C C T +C ++G+CI C N G C CLEG
Sbjct: 777 CDTCRENFYGLDVTNCKACDCDTAGSLPGT--VCNAKTGQCI-CKPNVEGRQCNKCLEGN 833
Query: 479 VHDLEGN 485
+ + N
Sbjct: 834 FYLRQNN 840
Score = 100 bits (250), Expect = 3e-21
Identities = 50/138 (36%), Positives = 75/138 (54%), Gaps = 9/138 (6%)
Query: 240 VCNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGL-CQPCDCSPHGA 298
+C C +G+L C+ +GQC C P QG C C+ GFY++ + C PC C GA
Sbjct: 899 MCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGA 958
Query: 299 LSIPCNS-SGKCQCK-VGVIGSICDRCQDGYYGF--SKNGCLPCQCNNRSA---SCDALT 351
++ CNS +G+C C+ + G CD+C+D Y+GF C PC C+ A +C +T
Sbjct: 959 VNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVT 1018
Query: 352 GACLNCQENSKGNHCEEC 369
G C C++ G+ C+ C
Sbjct: 1019 GQCF-CKQFVTGSKCDAC 1035
Score = 98.2 bits (243), Expect = 2e-20
Identities = 69/225 (30%), Positives = 94/225 (41%), Gaps = 46/225 (20%)
Query: 291 CDCSPHGALSIPCNSSGKCQCKVGVI--GSICDRCQ-----------DGYYGFSKNGCLP 337
C C H + +C C G CDRC D Y F+ C P
Sbjct: 518 CQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFN---CKP 574
Query: 338 CQCNNRSASCDALT--------------GACLNCQENSKGNHCEECKEGFYQ----SPDA 379
CQCN+ S SC G C +C+ N+ G +CE CK+ F++ P A
Sbjct: 575 CQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSA 634
Query: 380 TKECLRCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGYYNFDSI----CR 435
C C C V T + SI ++ +C+ CK G CN+C+NG+YN + C
Sbjct: 635 IDVCKPCDCDTV-GTRNGSILCDQIGGQCN-CKRHVSGRQCNQCQNGFYNLQELDPDGCS 692
Query: 436 KCQCH--GHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGY 478
C C+ G VD T C SG+C C N G C++C G+
Sbjct: 693 PCNCNTSGTVDGDIT---CHQNSGQC-KCKANVIGLRCDHCNFGF 733
Score = 96.7 bits (239), Expect = 6e-20
Identities = 72/253 (28%), Positives = 108/253 (42%), Gaps = 55/253 (21%)
Query: 268 QGLHCETC---------KEGFYLNYTSGLCQPCDCSPHGA-----LSIP-------CNSS 306
+GLHC+ C ++G + + C+PC C+ H +S+
Sbjct: 545 EGLHCDRCLPLYNDKPFRQGDQVYAFN--CKPCQCNSHSKSCHYNISVDPFPFEHFRGGG 602
Query: 307 GKC-QCKVGVIGSICDRCQDGYYGFSKNG--------CLPCQCN-----NRSASCDALTG 352
G C C+ G C+ C+D Y F + G C PC C+ N S CD + G
Sbjct: 603 GVCDDCEHNTTGRNCELCKD--YFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGG 660
Query: 353 ACLNCQENSKGNHCEECKEGFYQSPDATKE-CLRCPCSAVTSTGSCSIKSSELEPECDQC 411
C NC+ + G C +C+ GFY + + C C C+ + T I + +C +C
Sbjct: 661 QC-NCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCN-TSGTVDGDITCHQNSGQC-KC 717
Query: 412 KDGYIGPNCNKCENGY---YNFDSI-CRKCQC--HGHVDPVKTPKICKPESGECINCLHN 465
K IG C+ C G+ +F+ + C CQC HG V+ K C P SG+C C
Sbjct: 718 KANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVN-----KFCNPHSGQC-ECKKE 771
Query: 466 TTGFWCENCLEGY 478
G C+ C E +
Sbjct: 772 AKGLQCDTCRENF 784
Score = 33.1 bits (74), Expect = 0.81
Identities = 21/59 (35%), Positives = 25/59 (42%), Gaps = 15/59 (25%)
Query: 427 YYNFD--SICRKCQCHGHVDPVKTPK-----ICKPESGECINCLHNTTGFWCENCLEGY 478
YY D +I +CQCHGH D T +C ES T G C+ CL Y
Sbjct: 506 YYAVDEITISGRCQCHGHADNCDTTSQPYRCLCSQES--------FTEGLHCDRCLPLY 556
>gi|219842259 usherin isoform A [Homo sapiens]
Length = 1546
Score = 162 bits (411), Expect = 7e-40
Identities = 105/314 (33%), Positives = 154/314 (49%), Gaps = 24/314 (7%)
Query: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEG-FYLNY-TSGLCQPCDCSPHGA 298
C+C GSL CN TGQC C+P +G C C EG FYL S LC PC+C G
Sbjct: 795 CDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGT 854
Query: 299 L--SIPCN-SSGKCQCKVGVIGSICDRCQDGYYGFSKNG---CLPCQCNN----RSASCD 348
+ S+ CN S+G+C CK+GV G C++C+ Y + + C C+C++ CD
Sbjct: 855 INGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICD 914
Query: 349 ALTGACLNCQENSKGNHCEECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKSSELEPEC 408
++G CL C N +G C +C+ GFY SP CL C C +TG+ + + L +C
Sbjct: 915 PISGQCL-CVPNRQGRRCNQCQPGFYISPGNATGCLPCSCH---TTGAVNHICNSLTGQC 970
Query: 409 DQCKDGYI-GPNCNKCENGYYNFDSICRKCQ-CHGHVDPVKTPKICKPESGECINCLHNT 466
C+D I G C++C++ Y+ FD +CQ C+ H+ + C +G+C C
Sbjct: 971 -VCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALN-ETCHLVTGQCF-CKQFV 1027
Query: 467 TGFWCENCLEGYVH-DLEG--NCIKKEVILPTPEGSTILVSNASLTTSVPTPVINSTFTP 523
TG C+ C+ H D+ C K P P G S +L+ S P T
Sbjct: 1028 TGSKCDACVPSASHLDVNNLLGCSKTPFQQPPPRGQVQSSSAINLSWSPPDSPNAHWLTY 1087
Query: 524 TTLQTIFSVSTSEN 537
+ L+ F + T+E+
Sbjct: 1088 SLLRDGFEIYTTED 1101
Score = 152 bits (384), Expect = 9e-37
Identities = 87/253 (34%), Positives = 131/253 (51%), Gaps = 23/253 (9%)
Query: 241 CNCSVVGSLNVN-RCNQTTGQCECRPGYQGLHCETCKEGFYL--NYTSGLCQPCDCSPHG 297
CNC+ G+++ + C+Q +GQC+C+ GL C+ C GF ++ C+PC C+ HG
Sbjct: 694 CNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHG 753
Query: 298 ALSIPCN-SSGKCQCKVGVIGSICDRCQDGYYGFSKNGCLPCQCNNRSA----SCDALTG 352
+++ CN SG+C+CK G CD C++ +YG C C C+ + C+A TG
Sbjct: 754 SVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTG 813
Query: 353 ACLNCQENSKGNHCEECKEG-FYQSPDATKECLRCPCSAVTSTGSCSIKSSELEPECDQC 411
C+ C+ N +G C +C EG FY + + CL C C T T + S+ ++ +C C
Sbjct: 814 QCI-CKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDK-TGTINGSLLCNKSTGQC-PC 870
Query: 412 KDGYIGPNCNKCENGYYNFD----SICRKCQCHGHVDPVKT--PKICKPESGECINCLHN 465
K G G CN+CE YN C+ C+C D + T IC P SG+C+ C+ N
Sbjct: 871 KLGVTGLRCNQCEPHRYNLTIDNFQHCQMCEC----DSLGTLPGTICDPISGQCL-CVPN 925
Query: 466 TTGFWCENCLEGY 478
G C C G+
Sbjct: 926 RQGRRCNQCQPGF 938
Score = 134 bits (338), Expect = 2e-31
Identities = 89/285 (31%), Positives = 126/285 (44%), Gaps = 31/285 (10%)
Query: 211 CESNLKSKYLPLTQPVMNLRVS---EAVKTEYVCNCSVVGSLNVN-RCNQTTGQCECRPG 266
CE N + L + +V A+ C+C VG+ N + C+Q GQC C+
Sbjct: 608 CEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRH 667
Query: 267 YQGLHCETCKEGFY--LNYTSGLCQPCDCSPHGAL--SIPCN-SSGKCQCKVGVIGSICD 321
G C C+ GFY C PC+C+ G + I C+ +SG+C+CK VIG CD
Sbjct: 668 VSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCD 727
Query: 322 RCQDGY---YGFSKNGCLPCQCN---NRSASCDALTGACLNCQENSKGNHCEECKEGFYQ 375
C G+ F+ GC PCQCN + + C+ +G C C++ +KG C+ C+E FY
Sbjct: 728 HCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQC-ECKKEAKGLQCDTCRENFY- 785
Query: 376 SPDATKECLRCPCSAVTSTGS--CSIKSSELEPECDQCKDGYIGPNCNKCENGYY----N 429
D T C C C S C+ K+ + CK G CNKC G + N
Sbjct: 786 GLDVT-NCKACDCDTAGSLPGTVCNAKTGQC-----ICKPNVEGRQCNKCLEGNFYLRQN 839
Query: 430 FDSICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENC 474
+C C C + +C +G+C C TG C C
Sbjct: 840 NSFLCLPCNC-DKTGTINGSLLCNKSTGQC-PCKLGVTGLRCNQC 882
Score = 112 bits (280), Expect = 1e-24
Identities = 76/247 (30%), Positives = 109/247 (44%), Gaps = 29/247 (11%)
Query: 259 GQCE-CRPGYQGLHCETCKEGFYLNYTS-----GLCQPCDCSPHGAL--SIPCNS-SGKC 309
G C+ C G +CE CK+ F+ + +C+PCDC G SI C+ G+C
Sbjct: 603 GVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQC 662
Query: 310 QCKVGVIGSICDRCQDGYYGFSK---NGCLPCQCNNRSA-----SCDALTGACLNCQENS 361
CK V G C++CQ+G+Y + +GC PC CN +C +G C C+ N
Sbjct: 663 NCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQC-KCKANV 721
Query: 362 KGNHCEECKEGF-YQSPDATKECLRCPCSAVTSTGS-CSIKSSELEPECDQCKDGYIGPN 419
G C+ C GF + C C C+ S C+ S + E CK G
Sbjct: 722 IGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCE-----CKKEAKGLQ 776
Query: 420 CNKCENGYYNFD-SICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGY 478
C+ C +Y D + C+ C C T +C ++G+CI C N G C CLEG
Sbjct: 777 CDTCRENFYGLDVTNCKACDCDTAGSLPGT--VCNAKTGQCI-CKPNVEGRQCNKCLEGN 833
Query: 479 VHDLEGN 485
+ + N
Sbjct: 834 FYLRQNN 840
Score = 100 bits (250), Expect = 3e-21
Identities = 50/138 (36%), Positives = 75/138 (54%), Gaps = 9/138 (6%)
Query: 240 VCNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGL-CQPCDCSPHGA 298
+C C +G+L C+ +GQC C P QG C C+ GFY++ + C PC C GA
Sbjct: 899 MCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGA 958
Query: 299 LSIPCNS-SGKCQCK-VGVIGSICDRCQDGYYGF--SKNGCLPCQCNNRSA---SCDALT 351
++ CNS +G+C C+ + G CD+C+D Y+GF C PC C+ A +C +T
Sbjct: 959 VNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVT 1018
Query: 352 GACLNCQENSKGNHCEEC 369
G C C++ G+ C+ C
Sbjct: 1019 GQCF-CKQFVTGSKCDAC 1035
Score = 98.2 bits (243), Expect = 2e-20
Identities = 69/225 (30%), Positives = 94/225 (41%), Gaps = 46/225 (20%)
Query: 291 CDCSPHGALSIPCNSSGKCQCKVGVI--GSICDRCQ-----------DGYYGFSKNGCLP 337
C C H + +C C G CDRC D Y F+ C P
Sbjct: 518 CQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFN---CKP 574
Query: 338 CQCNNRSASCDALT--------------GACLNCQENSKGNHCEECKEGFYQ----SPDA 379
CQCN+ S SC G C +C+ N+ G +CE CK+ F++ P A
Sbjct: 575 CQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSA 634
Query: 380 TKECLRCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGYYNFDSI----CR 435
C C C V T + SI ++ +C+ CK G CN+C+NG+YN + C
Sbjct: 635 IDVCKPCDCDTV-GTRNGSILCDQIGGQCN-CKRHVSGRQCNQCQNGFYNLQELDPDGCS 692
Query: 436 KCQCH--GHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGY 478
C C+ G VD T C SG+C C N G C++C G+
Sbjct: 693 PCNCNTSGTVDGDIT---CHQNSGQC-KCKANVIGLRCDHCNFGF 733
Score = 96.7 bits (239), Expect = 6e-20
Identities = 72/253 (28%), Positives = 108/253 (42%), Gaps = 55/253 (21%)
Query: 268 QGLHCETC---------KEGFYLNYTSGLCQPCDCSPHGA-----LSIP-------CNSS 306
+GLHC+ C ++G + + C+PC C+ H +S+
Sbjct: 545 EGLHCDRCLPLYNDKPFRQGDQVYAFN--CKPCQCNSHSKSCHYNISVDPFPFEHFRGGG 602
Query: 307 GKC-QCKVGVIGSICDRCQDGYYGFSKNG--------CLPCQCN-----NRSASCDALTG 352
G C C+ G C+ C+D Y F + G C PC C+ N S CD + G
Sbjct: 603 GVCDDCEHNTTGRNCELCKD--YFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGG 660
Query: 353 ACLNCQENSKGNHCEECKEGFYQSPDATKE-CLRCPCSAVTSTGSCSIKSSELEPECDQC 411
C NC+ + G C +C+ GFY + + C C C+ + T I + +C +C
Sbjct: 661 QC-NCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCN-TSGTVDGDITCHQNSGQC-KC 717
Query: 412 KDGYIGPNCNKCENGY---YNFDSI-CRKCQC--HGHVDPVKTPKICKPESGECINCLHN 465
K IG C+ C G+ +F+ + C CQC HG V+ K C P SG+C C
Sbjct: 718 KANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVN-----KFCNPHSGQC-ECKKE 771
Query: 466 TTGFWCENCLEGY 478
G C+ C E +
Sbjct: 772 AKGLQCDTCRENF 784
Score = 33.1 bits (74), Expect = 0.81
Identities = 21/59 (35%), Positives = 25/59 (42%), Gaps = 15/59 (25%)
Query: 427 YYNFD--SICRKCQCHGHVDPVKTPK-----ICKPESGECINCLHNTTGFWCENCLEGY 478
YY D +I +CQCHGH D T +C ES T G C+ CL Y
Sbjct: 506 YYAVDEITISGRCQCHGHADNCDTTSQPYRCLCSQES--------FTEGLHCDRCLPLY 556
>gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo
sapiens]
Length = 3118
Score = 159 bits (402), Expect = 7e-39
Identities = 81/243 (33%), Positives = 116/243 (47%), Gaps = 15/243 (6%)
Query: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALS 300
C C+ GS + C+ TGQCECR QG C+ CK G + ++ C PC+C+ G+ S
Sbjct: 918 CRCNAGGSFS-EVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKS 976
Query: 301 IPCNSSGKCQCKVGVIGSICDRCQDGYYGFSKNGCLPCQCNNRSASCDALTGACLNCQEN 360
C SG+C C+ GV G CDRC GY+ F + GC C+C++ +CD TG C+ C N
Sbjct: 977 FDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNNCDPKTGRCI-CPPN 1035
Query: 361 SKGNHCEECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNC 420
+ G C +C + T C C CS V GS + + +C+ C + G C
Sbjct: 1036 TIGEKCSKCAPNTW-GHSITTGCKACNCSTV---GSLDFQCNVNTGQCN-CHPKFSGAKC 1090
Query: 421 NKCENGYYNFDSICRKCQCH------GHVDPVKTPKICKPESGECINCLHNTTGFWCENC 474
+C G++N+ C C C D C ++G+C C N G C+ C
Sbjct: 1091 TECSRGHWNYPR-CNLCDCFLPGTDATTCDSETKKCSCSDQTGQC-TCKVNVEGIHCDRC 1148
Query: 475 LEG 477
G
Sbjct: 1149 RPG 1151
Score = 137 bits (345), Expect = 3e-32
Identities = 91/303 (30%), Positives = 127/303 (41%), Gaps = 81/303 (26%)
Query: 254 CNQTTGQC-ECRPGYQGLHCETCKEGFYLNYTSGL---CQPCDCSPHGALSIPCNS-SGK 308
C+ TG+C C+ G +C+ C GFY T G CQPC C L+IP N+ S
Sbjct: 766 CDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACP----LNIPSNNFSPT 821
Query: 309 CQ-----------CKVGVIGSICDRCQDGYYGFSK---NGCLPCQCNNR-----SASCDA 349
C C VG G C+RC +GY+G C PCQCN+ SCD+
Sbjct: 822 CHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDS 881
Query: 350 LTGACLNCQENSKGNHCEECKEGFYQSPDATKECLRCPCSAVTS--------TGSCSIKS 401
L+G+CL C+ + G +CE C +G++ K C C C+A S TG C ++
Sbjct: 882 LSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRA 941
Query: 402 SELEPECDQCK------------------------------------DGYIGPNCNKCEN 425
+ CD+CK G G C++C +
Sbjct: 942 NVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAH 1001
Query: 426 GYYNF-DSICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEG-YVHDLE 483
GY+NF + C C+C H+ C P++G CI C NT G C C + H +
Sbjct: 1002 GYFNFQEGGCTACEC-SHLG-----NNCDPKTGRCI-CPPNTIGEKCSKCAPNTWGHSIT 1054
Query: 484 GNC 486
C
Sbjct: 1055 TGC 1057
Score = 132 bits (333), Expect = 7e-31
Identities = 75/217 (34%), Positives = 107/217 (49%), Gaps = 27/217 (12%)
Query: 281 LNYTSGLCQPCDCSPHGALSIPCNSSGKCQCKVGVIGSICDRCQDGYYGFSKNG------ 334
+N S + P D S A+ + CQC G GS C+ C + NG
Sbjct: 703 VNLESAVSYPTDGSIAAAVEV-------CQCPPGYTGSSCESCWPRHRRV--NGTIFGGI 753
Query: 335 CLPCQCNNRSASCDALTGACLNCQENSKGNHCEECKEGFYQSP--DATKECLRCPC---- 388
C PCQC + SCD +TG CLNC++++ G +C++C GFY P +++C C C
Sbjct: 754 CEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNI 813
Query: 389 SAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGYYNFDSI----CRKCQCHGHVD 444
+ + +C + S L CD C GY GP C +C GY+ S+ C+ CQC+ ++D
Sbjct: 814 PSNNFSPTCHLDRS-LGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLD 872
Query: 445 PVKTPKICKPESGECINCLHNTTGFWCENCLEGYVHD 481
P C SG C+ C TTG +CE C +GY D
Sbjct: 873 -FSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGD 908
Score = 107 bits (268), Expect = 3e-23
Identities = 61/193 (31%), Positives = 86/193 (44%), Gaps = 25/193 (12%)
Query: 302 PCNSSGKCQCKVGVIGSICDRCQDGYY-----------GFSKNGCLPCQCNNRSASCDAL 350
P + KC C +G G C+ C G+Y G + C+PCQCN S+ CD
Sbjct: 1373 PADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPE 1432
Query: 351 TGACLNCQENSKGNHCEECKEGFYQ-SPDATKECLRCPCSAVTSTGSCS---IKSSELEP 406
T C NCQ ++ G+ CE C G+Y +C +C C ++S+ + S + +
Sbjct: 1433 TSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDY 1492
Query: 407 ECDQCKDGYIGPNCNKCENGYY----NFDSICRKCQCHGHVDPV-KTPKICKPESGECIN 461
C C GY G C +C GY N C++C+C DP P C P +G C
Sbjct: 1493 RCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECEC----DPYGSLPVPCDPVTGFC-T 1547
Query: 462 CLHNTTGFWCENC 474
C TG C+ C
Sbjct: 1548 CRPGATGRKCDGC 1560
Score = 98.6 bits (244), Expect = 2e-20
Identities = 56/202 (27%), Positives = 88/202 (43%), Gaps = 42/202 (20%)
Query: 302 PCNSSGKCQCKVGVIGSICDRCQDGYYG--------FSKNGCLPCQCNNRSASCD----- 348
P + +C+C+ G CD+C G++ +K C C C+ ++ C
Sbjct: 300 PATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENV 359
Query: 349 -----ALT--------GACLNCQENSKGNHCEECKEGFYQ----SPDATKECLRCPCSAV 391
+L G C+NC +N+ G +CE C +GF++ SP+ + C C C +
Sbjct: 360 ARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPI 419
Query: 392 TSTGSCSIKSSE-----LEPECDQCKDGYIGPNCNKCENGYYNFDSICRKCQCHG----H 442
S +K + L P CK G+ G +C++C GY + C+ C C G +
Sbjct: 420 GSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPD-CKACNCSGLGSKN 478
Query: 443 VDPVKTPKICKP--ESGECINC 462
DP P ICK E G+C C
Sbjct: 479 EDPCFGPCICKENVEGGDCSRC 500
Score = 97.4 bits (241), Expect = 3e-20
Identities = 63/185 (34%), Positives = 77/185 (41%), Gaps = 34/185 (18%)
Query: 260 QCECRPGYQGLHCETCKEGFYL----------NYTSGLCQPCDCSPHGALSIPCNSSGKC 309
+C+C GY GL CE C GFY T G C PC C+ H +L P + C
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDP--ETSIC 1436
Query: 310 Q-CKVGVIGSICDRCQDGYYGFSK---NGCLPCQC------NNRSASCDAL---TGACLN 356
Q C+ G C+RC GYYG K N C C C NN S SC A C
Sbjct: 1437 QNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTA 1496
Query: 357 CQENSKGNHCEECKEGFYQSP-DATKECLRCPCSAVTS--------TGSCSIKSSELEPE 407
C +G +CE C G+ SP + C C C S TG C+ + +
Sbjct: 1497 CPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRK 1556
Query: 408 CDQCK 412
CD CK
Sbjct: 1557 CDGCK 1561
Score = 95.9 bits (237), Expect = 1e-19
Identities = 60/165 (36%), Positives = 76/165 (46%), Gaps = 23/165 (13%)
Query: 248 SLNVNRCNQTTGQC-ECRPGYQGLHCETCKEGFYL------NYTSGLCQPCDCSPHGALS 300
SLN+ G C C G++CETC +GF+ NY CQPC C P G+L+
Sbjct: 365 SLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRP-CQPCHCDPIGSLN 423
Query: 301 IPCNSS----------GKCQCKVGVIGSICDRCQDGYYGFSKNGCLPCQCNNR-SASCDA 349
C G C CK G G CDRC GY G+ C C C+ S + D
Sbjct: 424 EVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPD--CKACNCSGLGSKNEDP 481
Query: 350 LTGACLNCQENSKGNHCEECKEGFYQ-SPDATKECLRCPCSAVTS 393
G C+ C+EN +G C CK GF+ D K C C CS V++
Sbjct: 482 CFGPCI-CKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCSGVSN 525
Score = 90.5 bits (223), Expect = 4e-18
Identities = 50/125 (40%), Positives = 62/125 (49%), Gaps = 17/125 (13%)
Query: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALS 300
CNCS VGSL+ +CN TGQC C P + G C C G + NY C CDC G +
Sbjct: 1060 CNCSTVGSLDF-QCNVNTGQCNCHPKFSGAKCTECSRGHW-NYPR--CNLCDCFLPGTDA 1115
Query: 301 IPCNS----------SGKCQCKVGVIGSICDRCQDGYYGF-SKN--GCLPCQCNNRSASC 347
C+S +G+C CKV V G CDRC+ G +G +KN GC C C + C
Sbjct: 1116 TTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTTQC 1175
Query: 348 DALTG 352
G
Sbjct: 1176 SEAKG 1180
Score = 69.7 bits (169), Expect = 8e-12
Identities = 40/121 (33%), Positives = 57/121 (47%), Gaps = 17/121 (14%)
Query: 241 CNCSVVGSLNV--------NRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGLCQPCD 292
C+C +GSLN R G C C+ G+ G+ C+ C G Y Y C+ C+
Sbjct: 414 CHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARG-YTGYPD--CKACN 470
Query: 293 CSPHGALSI-PCNSSGKCQCKVGVIGSICDRCQDGYYGFSKN---GCLPCQCNNRSASCD 348
CS G+ + PC G C CK V G C RC+ G++ ++ GC C C+ S C
Sbjct: 471 CSGLGSKNEDPC--FGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCSGVSNRCQ 528
Query: 349 A 349
+
Sbjct: 529 S 529
Score = 62.4 bits (150), Expect = 1e-09
Identities = 34/102 (33%), Positives = 47/102 (46%), Gaps = 19/102 (18%)
Query: 395 GSCSIKSSELEPECDQCKDGYIGPNCNKCENGYYNFDS------------ICRKCQCHGH 442
G+ ++L +CD C GY G +C C G+Y S C CQC+GH
Sbjct: 1367 GTTMTPPADLIEKCD-CPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGH 1425
Query: 443 VDPVKTPKICKPESGECINCLHNTTGFWCENCLEGYVHDLEG 484
+C PE+ C NC H+T G +CE C GY ++G
Sbjct: 1426 ------SSLCDPETSICQNCQHHTAGDFCERCALGYYGIVKG 1461
Score = 49.7 bits (117), Expect = 8e-06
Identities = 27/105 (25%), Positives = 39/105 (37%), Gaps = 15/105 (14%)
Query: 386 CPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGYYNFDSICRKCQCHGHVDP 445
CP T+ C + + CDQC G+ + G + + C C CHG +
Sbjct: 296 CPLDPATNKSRCECEHNTCGDSCDQCCPGF---HQKPWRAGTFLTKTECEACNCHGKAEE 352
Query: 446 VKTPKICKPES------------GECINCLHNTTGFWCENCLEGY 478
+ + G CINC NT G CE C +G+
Sbjct: 353 CYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGF 397
Score = 48.9 bits (115), Expect = 1e-05
Identities = 35/133 (26%), Positives = 46/133 (34%), Gaps = 10/133 (7%)
Query: 356 NCQENSKGNHCEECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKSSELEPE---CDQCK 412
+C G CE C GFY+ P C+ SS +PE C C+
Sbjct: 1381 DCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQ 1440
Query: 413 DGYIGPNCNKCENGYYNF----DSICRKCQCHGHVDPVKTPKICKPESGE---CINCLHN 465
G C +C GYY + C++C C C E + C C
Sbjct: 1441 HHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRG 1500
Query: 466 TTGFWCENCLEGY 478
G +CE C GY
Sbjct: 1501 YEGQYCERCAPGY 1513
Score = 40.0 bits (92), Expect = 0.007
Identities = 18/36 (50%), Positives = 20/36 (55%), Gaps = 1/36 (2%)
Query: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCK 276
C C GSL V C+ TG C CRPG G C+ CK
Sbjct: 1527 CECDPYGSLPVP-CDPVTGFCTCRPGATGRKCDGCK 1561
>gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo
sapiens]
Length = 3122
Score = 159 bits (402), Expect = 7e-39
Identities = 81/243 (33%), Positives = 116/243 (47%), Gaps = 15/243 (6%)
Query: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALS 300
C C+ GS + C+ TGQCECR QG C+ CK G + ++ C PC+C+ G+ S
Sbjct: 918 CRCNAGGSFS-EVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKS 976
Query: 301 IPCNSSGKCQCKVGVIGSICDRCQDGYYGFSKNGCLPCQCNNRSASCDALTGACLNCQEN 360
C SG+C C+ GV G CDRC GY+ F + GC C+C++ +CD TG C+ C N
Sbjct: 977 FDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNNCDPKTGRCI-CPPN 1035
Query: 361 SKGNHCEECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNC 420
+ G C +C + T C C CS V GS + + +C+ C + G C
Sbjct: 1036 TIGEKCSKCAPNTW-GHSITTGCKACNCSTV---GSLDFQCNVNTGQCN-CHPKFSGAKC 1090
Query: 421 NKCENGYYNFDSICRKCQCH------GHVDPVKTPKICKPESGECINCLHNTTGFWCENC 474
+C G++N+ C C C D C ++G+C C N G C+ C
Sbjct: 1091 TECSRGHWNYPR-CNLCDCFLPGTDATTCDSETKKCSCSDQTGQC-TCKVNVEGIHCDRC 1148
Query: 475 LEG 477
G
Sbjct: 1149 RPG 1151
Score = 137 bits (345), Expect = 3e-32
Identities = 91/303 (30%), Positives = 127/303 (41%), Gaps = 81/303 (26%)
Query: 254 CNQTTGQC-ECRPGYQGLHCETCKEGFYLNYTSGL---CQPCDCSPHGALSIPCNS-SGK 308
C+ TG+C C+ G +C+ C GFY T G CQPC C L+IP N+ S
Sbjct: 766 CDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACP----LNIPSNNFSPT 821
Query: 309 CQ-----------CKVGVIGSICDRCQDGYYGFSK---NGCLPCQCNNR-----SASCDA 349
C C VG G C+RC +GY+G C PCQCN+ SCD+
Sbjct: 822 CHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDS 881
Query: 350 LTGACLNCQENSKGNHCEECKEGFYQSPDATKECLRCPCSAVTS--------TGSCSIKS 401
L+G+CL C+ + G +CE C +G++ K C C C+A S TG C ++
Sbjct: 882 LSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRA 941
Query: 402 SELEPECDQCK------------------------------------DGYIGPNCNKCEN 425
+ CD+CK G G C++C +
Sbjct: 942 NVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAH 1001
Query: 426 GYYNF-DSICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEG-YVHDLE 483
GY+NF + C C+C H+ C P++G CI C NT G C C + H +
Sbjct: 1002 GYFNFQEGGCTACEC-SHLG-----NNCDPKTGRCI-CPPNTIGEKCSKCAPNTWGHSIT 1054
Query: 484 GNC 486
C
Sbjct: 1055 TGC 1057
Score = 132 bits (333), Expect = 7e-31
Identities = 75/217 (34%), Positives = 107/217 (49%), Gaps = 27/217 (12%)
Query: 281 LNYTSGLCQPCDCSPHGALSIPCNSSGKCQCKVGVIGSICDRCQDGYYGFSKNG------ 334
+N S + P D S A+ + CQC G GS C+ C + NG
Sbjct: 703 VNLESAVSYPTDGSIAAAVEV-------CQCPPGYTGSSCESCWPRHRRV--NGTIFGGI 753
Query: 335 CLPCQCNNRSASCDALTGACLNCQENSKGNHCEECKEGFYQSP--DATKECLRCPC---- 388
C PCQC + SCD +TG CLNC++++ G +C++C GFY P +++C C C
Sbjct: 754 CEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNI 813
Query: 389 SAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGYYNFDSI----CRKCQCHGHVD 444
+ + +C + S L CD C GY GP C +C GY+ S+ C+ CQC+ ++D
Sbjct: 814 PSNNFSPTCHLDRS-LGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLD 872
Query: 445 PVKTPKICKPESGECINCLHNTTGFWCENCLEGYVHD 481
P C SG C+ C TTG +CE C +GY D
Sbjct: 873 -FSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGD 908
Score = 107 bits (268), Expect = 3e-23
Identities = 61/193 (31%), Positives = 86/193 (44%), Gaps = 25/193 (12%)
Query: 302 PCNSSGKCQCKVGVIGSICDRCQDGYY-----------GFSKNGCLPCQCNNRSASCDAL 350
P + KC C +G G C+ C G+Y G + C+PCQCN S+ CD
Sbjct: 1373 PADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPE 1432
Query: 351 TGACLNCQENSKGNHCEECKEGFYQ-SPDATKECLRCPCSAVTSTGSCS---IKSSELEP 406
T C NCQ ++ G+ CE C G+Y +C +C C ++S+ + S + +
Sbjct: 1433 TSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDY 1492
Query: 407 ECDQCKDGYIGPNCNKCENGYY----NFDSICRKCQCHGHVDPV-KTPKICKPESGECIN 461
C C GY G C +C GY N C++C+C DP P C P +G C
Sbjct: 1493 RCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECEC----DPYGSLPVPCDPVTGFC-T 1547
Query: 462 CLHNTTGFWCENC 474
C TG C+ C
Sbjct: 1548 CRPGATGRKCDGC 1560
Score = 98.6 bits (244), Expect = 2e-20
Identities = 56/202 (27%), Positives = 88/202 (43%), Gaps = 42/202 (20%)
Query: 302 PCNSSGKCQCKVGVIGSICDRCQDGYYG--------FSKNGCLPCQCNNRSASCD----- 348
P + +C+C+ G CD+C G++ +K C C C+ ++ C
Sbjct: 300 PATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENV 359
Query: 349 -----ALT--------GACLNCQENSKGNHCEECKEGFYQ----SPDATKECLRCPCSAV 391
+L G C+NC +N+ G +CE C +GF++ SP+ + C C C +
Sbjct: 360 ARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPI 419
Query: 392 TSTGSCSIKSSE-----LEPECDQCKDGYIGPNCNKCENGYYNFDSICRKCQCHG----H 442
S +K + L P CK G+ G +C++C GY + C+ C C G +
Sbjct: 420 GSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPD-CKACNCSGLGSKN 478
Query: 443 VDPVKTPKICKP--ESGECINC 462
DP P ICK E G+C C
Sbjct: 479 EDPCFGPCICKENVEGGDCSRC 500
Score = 97.4 bits (241), Expect = 3e-20
Identities = 63/185 (34%), Positives = 77/185 (41%), Gaps = 34/185 (18%)
Query: 260 QCECRPGYQGLHCETCKEGFYL----------NYTSGLCQPCDCSPHGALSIPCNSSGKC 309
+C+C GY GL CE C GFY T G C PC C+ H +L P + C
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDP--ETSIC 1436
Query: 310 Q-CKVGVIGSICDRCQDGYYGFSK---NGCLPCQC------NNRSASCDAL---TGACLN 356
Q C+ G C+RC GYYG K N C C C NN S SC A C
Sbjct: 1437 QNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTA 1496
Query: 357 CQENSKGNHCEECKEGFYQSP-DATKECLRCPCSAVTS--------TGSCSIKSSELEPE 407
C +G +CE C G+ SP + C C C S TG C+ + +
Sbjct: 1497 CPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRK 1556
Query: 408 CDQCK 412
CD CK
Sbjct: 1557 CDGCK 1561
Score = 95.9 bits (237), Expect = 1e-19
Identities = 60/165 (36%), Positives = 76/165 (46%), Gaps = 23/165 (13%)
Query: 248 SLNVNRCNQTTGQC-ECRPGYQGLHCETCKEGFYL------NYTSGLCQPCDCSPHGALS 300
SLN+ G C C G++CETC +GF+ NY CQPC C P G+L+
Sbjct: 365 SLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRP-CQPCHCDPIGSLN 423
Query: 301 IPCNSS----------GKCQCKVGVIGSICDRCQDGYYGFSKNGCLPCQCNNR-SASCDA 349
C G C CK G G CDRC GY G+ C C C+ S + D
Sbjct: 424 EVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPD--CKACNCSGLGSKNEDP 481
Query: 350 LTGACLNCQENSKGNHCEECKEGFYQ-SPDATKECLRCPCSAVTS 393
G C+ C+EN +G C CK GF+ D K C C CS V++
Sbjct: 482 CFGPCI-CKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCSGVSN 525
Score = 90.5 bits (223), Expect = 4e-18
Identities = 50/125 (40%), Positives = 62/125 (49%), Gaps = 17/125 (13%)
Query: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALS 300
CNCS VGSL+ +CN TGQC C P + G C C G + NY C CDC G +
Sbjct: 1060 CNCSTVGSLDF-QCNVNTGQCNCHPKFSGAKCTECSRGHW-NYPR--CNLCDCFLPGTDA 1115
Query: 301 IPCNS----------SGKCQCKVGVIGSICDRCQDGYYGF-SKN--GCLPCQCNNRSASC 347
C+S +G+C CKV V G CDRC+ G +G +KN GC C C + C
Sbjct: 1116 TTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTTQC 1175
Query: 348 DALTG 352
G
Sbjct: 1176 SEAKG 1180
Score = 69.7 bits (169), Expect = 8e-12
Identities = 40/121 (33%), Positives = 57/121 (47%), Gaps = 17/121 (14%)
Query: 241 CNCSVVGSLNV--------NRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGLCQPCD 292
C+C +GSLN R G C C+ G+ G+ C+ C G Y Y C+ C+
Sbjct: 414 CHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARG-YTGYPD--CKACN 470
Query: 293 CSPHGALSI-PCNSSGKCQCKVGVIGSICDRCQDGYYGFSKN---GCLPCQCNNRSASCD 348
CS G+ + PC G C CK V G C RC+ G++ ++ GC C C+ S C
Sbjct: 471 CSGLGSKNEDPC--FGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCSGVSNRCQ 528
Query: 349 A 349
+
Sbjct: 529 S 529
Score = 62.4 bits (150), Expect = 1e-09
Identities = 34/102 (33%), Positives = 47/102 (46%), Gaps = 19/102 (18%)
Query: 395 GSCSIKSSELEPECDQCKDGYIGPNCNKCENGYYNFDS------------ICRKCQCHGH 442
G+ ++L +CD C GY G +C C G+Y S C CQC+GH
Sbjct: 1367 GTTMTPPADLIEKCD-CPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGH 1425
Query: 443 VDPVKTPKICKPESGECINCLHNTTGFWCENCLEGYVHDLEG 484
+C PE+ C NC H+T G +CE C GY ++G
Sbjct: 1426 ------SSLCDPETSICQNCQHHTAGDFCERCALGYYGIVKG 1461
Score = 49.7 bits (117), Expect = 8e-06
Identities = 27/105 (25%), Positives = 39/105 (37%), Gaps = 15/105 (14%)
Query: 386 CPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGYYNFDSICRKCQCHGHVDP 445
CP T+ C + + CDQC G+ + G + + C C CHG +
Sbjct: 296 CPLDPATNKSRCECEHNTCGDSCDQCCPGF---HQKPWRAGTFLTKTECEACNCHGKAEE 352
Query: 446 VKTPKICKPES------------GECINCLHNTTGFWCENCLEGY 478
+ + G CINC NT G CE C +G+
Sbjct: 353 CYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGF 397
Score = 48.9 bits (115), Expect = 1e-05
Identities = 35/133 (26%), Positives = 46/133 (34%), Gaps = 10/133 (7%)
Query: 356 NCQENSKGNHCEECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKSSELEPE---CDQCK 412
+C G CE C GFY+ P C+ SS +PE C C+
Sbjct: 1381 DCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQ 1440
Query: 413 DGYIGPNCNKCENGYYNF----DSICRKCQCHGHVDPVKTPKICKPESGE---CINCLHN 465
G C +C GYY + C++C C C E + C C
Sbjct: 1441 HHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRG 1500
Query: 466 TTGFWCENCLEGY 478
G +CE C GY
Sbjct: 1501 YEGQYCERCAPGY 1513
Score = 40.0 bits (92), Expect = 0.007
Identities = 18/36 (50%), Positives = 20/36 (55%), Gaps = 1/36 (2%)
Query: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCK 276
C C GSL V C+ TG C CRPG G C+ CK
Sbjct: 1527 CECDPYGSLPVP-CDPVTGFCTCRPGATGRKCDGCK 1561
>gi|38788416 laminin, alpha 1 precursor [Homo sapiens]
Length = 3075
Score = 155 bits (392), Expect = 1e-37
Identities = 85/244 (34%), Positives = 116/244 (47%), Gaps = 17/244 (6%)
Query: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALS 300
C C V GS + C+ TG C+C+P G C+ C G+Y + C+PC+CS G++S
Sbjct: 902 CECHVKGSHSAV-CHLETGLCDCKPNVTGQQCDQCLHGYYGLDSGHGCRPCNCSVAGSVS 960
Query: 301 IPCNSSGKCQCKVGVIGSICDRCQDGYYGFSKNGCLPCQCNNRSASCDALTGACLNCQEN 360
C G+C C GV G CDRC G+Y + C PC C + +CD TG C+ C +
Sbjct: 961 DGCTDEGQCHCVPGVAGKRCDRCAHGFYAYQDGSCTPCDCPHTQNTCDPETGECV-CPPH 1019
Query: 361 SKGNHCEECKEGFYQSPDATKECLRCPCSAVTST-GSCSIKSSELEPECDQCKDGYIGPN 419
++G CEEC++G + DA C C CS V ST C + + QCK + G
Sbjct: 1020 TQGVKCEECEDGHW-GYDAEVGCQACNCSLVGSTHHRCDVVTGHC-----QCKSKFGGRA 1073
Query: 420 CNKCENGYYNFDSICRKCQCHGHVDPVKTPKI------CKPESGECINCLHNTTGFWCEN 473
C++C GY +F C C C + C E+G C C N G C
Sbjct: 1074 CDQCSLGYRDFPD-CVPCDCDLRGTSGDACNLEQGLCGCVEETGAC-PCKENVFGPQCNE 1131
Query: 474 CLEG 477
C EG
Sbjct: 1132 CREG 1135
Score = 145 bits (367), Expect = 9e-35
Identities = 110/354 (31%), Positives = 139/354 (39%), Gaps = 93/354 (26%)
Query: 202 PQKYLGKYACESNLKSKYLPLTQPVMNLRVSEAVKTEYVCNCSVVGSLNVNRCNQTTGQC 261
PQ Y G +CES L Y RV + C G + CN
Sbjct: 712 PQGYTGT-SCESCLSGYY----------RVDGILFGGICQPCECHG--HAAECNVHGVCI 758
Query: 262 ECRPGYQGLHCETCKEGFY---LNYTSGLCQPCDCSPHGALSIPCNS-SGKCQ------- 310
C G+HCE C GFY T G CQPC C L+I N+ S C
Sbjct: 759 ACAHNTTGVHCEQCLPGFYGEPSRGTPGDCQPCACP----LTIASNNFSPTCHLNDGDEV 814
Query: 311 ----CKVGVIGSICDRCQDGYYG---FSKNGCLPCQCN-----NRSASCDALTGACLNCQ 358
C G G+ C+RC DGYYG C+PC C+ + + CD++TG CL C
Sbjct: 815 VCDWCAPGYSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCL 874
Query: 359 ENSKGNHCEECKEGFYQSPDATKECLRCPC------SAV--TSTGSCSIKSSELEPECDQ 410
N+ G HCE C +GFY K C C C SAV TG C K + +CDQ
Sbjct: 875 GNTDGAHCERCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQ 934
Query: 411 CKDGY------------------------------------IGPNCNKCENGYYNF-DSI 433
C GY G C++C +G+Y + D
Sbjct: 935 CLHGYYGLDSGHGCRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCDRCAHGFYAYQDGS 994
Query: 434 CRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEG-YVHDLEGNC 486
C C C T C PE+GEC+ C +T G CE C +G + +D E C
Sbjct: 995 CTPCDC------PHTQNTCDPETGECV-CPPHTQGVKCEECEDGHWGYDAEVGC 1041
Score = 115 bits (289), Expect = 9e-26
Identities = 69/231 (29%), Positives = 104/231 (45%), Gaps = 29/231 (12%)
Query: 309 CQCKVGVIGSICDRCQDGYY-----GFSKNG-------CLPCQCNNRSASCDALTGACLN 356
C C G +G C C GY+ S G C+PC CNN S +CD TG CLN
Sbjct: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKCLN 1421
Query: 357 CQENSKGNHCEECKEGFY-QSPDATKECLRCPC--SAVTSTGSCSIKSSELEPECDQCKD 413
C +N+ G+HC+ C G+Y + + +C C C S S + + + CD C
Sbjct: 1422 CGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGDHDFRCDACLL 1481
Query: 414 GYIGPNCNKCENGYYNFDSI----CRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGF 469
GY G +C +C + YY C+KC C+ H C SG+C+ C +G
Sbjct: 1482 GYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPH---GSVHGDCDRTSGQCV-CRLGASGL 1537
Query: 470 WCENCLEGYVHDLEGNCIKKE-----VILPTPEGSTILVSNASLTTSVPTP 515
C+ C ++ +E +C+ + V+L + V + +LT +P P
Sbjct: 1538 RCDECEPRHIL-METDCVSCDDECVGVLLNDLDEIGDAVLSLNLTGIIPVP 1587
Score = 101 bits (252), Expect = 2e-21
Identities = 73/235 (31%), Positives = 107/235 (45%), Gaps = 48/235 (20%)
Query: 291 CDCSPHGALSIPCNSSGK---CQCKVGVIGSICDRCQDGYYG--------FSKNGCLPCQ 339
C C H A S P + + K CQC+ G C+RC GY+ S N C C
Sbjct: 270 CICYGH-ASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACN 328
Query: 340 CNNRSASC----------DALT--------GACLNCQENSKGNHCEECKEGFYQ----SP 377
C+N++ C +L G C+NC +N+ G +CE C +G+Y+ SP
Sbjct: 329 CHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSP 388
Query: 378 DATKECLRCPCSAVTSTGSCSIKS---SEL----EPECDQCKDGYIGPNCNKCENGYYNF 430
+ C C C V S S IK S+L +P CK+GY G C++C+ GY ++
Sbjct: 389 YEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDY 448
Query: 431 DSICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGYVHDLEGN 485
+ C C C +PV + +P +G C+ C N G C+ C G+ + E N
Sbjct: 449 PT-CVSCGC----NPVGSAS-DEPCTGPCV-CKENVEGKACDRCKPGFYNLKEKN 496
Score = 99.8 bits (247), Expect = 7e-21
Identities = 61/169 (36%), Positives = 80/169 (47%), Gaps = 23/169 (13%)
Query: 248 SLNVNRCNQTTGQC-ECRPGYQGLHCETCKEGFYLN-----YTSGLCQPCDCSPHGALSI 301
SLN + G C C G++CETC +G+Y Y C+PC+C P G+LS
Sbjct: 348 SLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSS 407
Query: 302 PC------------NSSGKCQCKVGVIGSICDRCQDGYYGFSKNGCLPCQCNN-RSASCD 348
C G+C CK G G CDRCQ GY + C+ C CN SAS +
Sbjct: 408 VCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYPT--CVSCGCNPVGSASDE 465
Query: 349 ALTGACLNCQENSKGNHCEECKEGFYQSPDAT-KECLRCPCSAVTSTGS 396
TG C+ C+EN +G C+ CK GFY + + C C C V+ S
Sbjct: 466 PCTGPCV-CKENVEGKACDRCKPGFYNLKEKNPRGCSECFCFGVSDVCS 513
Score = 83.2 bits (204), Expect = 7e-16
Identities = 43/123 (34%), Positives = 60/123 (48%), Gaps = 17/123 (13%)
Query: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALS 300
CNCS+VGS + +RC+ TG C+C+ + G C+ C G Y ++ C PCDC G
Sbjct: 1044 CNCSLVGSTH-HRCDVVTGHCQCKSKFGGRACDQCSLG-YRDFPD--CVPCDCDLRGTSG 1099
Query: 301 IPCN----------SSGKCQCKVGVIGSICDRCQDGYYGFSKN---GCLPCQCNNRSASC 347
CN +G C CK V G C+ C++G + + GC PC C+ S C
Sbjct: 1100 DACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFALRADNPLGCSPCFCSGLSHLC 1159
Query: 348 DAL 350
L
Sbjct: 1160 SEL 1162
Score = 81.3 bits (199), Expect = 3e-15
Identities = 60/209 (28%), Positives = 82/209 (39%), Gaps = 36/209 (17%)
Query: 261 CECRPGYQGLHCETCKEGFYLNYTS-----------GLCQPCDCSPHGALSIPCNSSGKC 309
C C PG G C+ C G++ C PC C+ H P ++GKC
Sbjct: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDP--NTGKC 1419
Query: 310 -QCKVGVIGSICDRCQDGYYG---FSKNGCLPCQCNNR-----SASCDALTG----ACLN 356
C G CD C GYYG S + C C C + S +C L G C
Sbjct: 1420 LNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPTC-VLEGDHDFRCDA 1478
Query: 357 CQENSKGNHCEECKEGFYQSPDAT-KECLRCPCSAVTST-GSCSIKSSELEPECDQCKDG 414
C +G HCE C +Y +P C +C C+ S G C S + C+ G
Sbjct: 1479 CLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQC-----VCRLG 1533
Query: 415 YIGPNCNKCENGYYNFDSICRKC--QCHG 441
G C++CE + ++ C C +C G
Sbjct: 1534 ASGLRCDECEPRHILMETDCVSCDDECVG 1562
Score = 78.6 bits (192), Expect = 2e-14
Identities = 47/126 (37%), Positives = 63/126 (50%), Gaps = 21/126 (16%)
Query: 241 CNCSVVGSLNVNRC-----------NQTTGQCECRPGYQGLHCETCKEGFYLNYTSGLCQ 289
CNC VGSL+ + C + GQC C+ GY G C+ C+ G Y +Y + C
Sbjct: 397 CNCDPVGSLS-SVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLG-YKDYPT--CV 452
Query: 290 PCDCSPHGALS-IPCNSSGKCQCKVGVIGSICDRCQDGYYGFSK---NGCLPCQCNNRSA 345
C C+P G+ S PC +G C CK V G CDRC+ G+Y + GC C C S
Sbjct: 453 SCGCNPVGSASDEPC--TGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFCFGVSD 510
Query: 346 SCDALT 351
C +L+
Sbjct: 511 VCSSLS 516
Score = 64.3 bits (155), Expect = 3e-10
Identities = 58/239 (24%), Positives = 85/239 (35%), Gaps = 71/239 (29%)
Query: 260 QCECRPGYQGLHCETCKEGFYLN-------YTSGLCQPCDC----------SPHGALSIP 302
QC+C G C C G++ + C+ C+C
Sbjct: 289 QCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKS 348
Query: 303 CNSSGK-------CQCKVGVIGSICDRCQDGYY------GFSKNGCLPCQCN---NRSAS 346
N++G+ C +G C+ C DGYY + C PC C+ + S+
Sbjct: 349 LNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSV 408
Query: 347 C--DAL---------TGACLNCQENSKGNHCEECKEGFYQSPDATKECLRCPCSAVTS-- 393
C D L G C C+E G C+ C+ G+ P C+ C C+ V S
Sbjct: 409 CIKDDLHSDLHNGKQPGQC-PCKEGYTGEKCDRCQLGYKDYP----TCVSCGCNPVGSAS 463
Query: 394 ----TGSCSIKSSELEPECDQCKDGYIGPNCNKCENGYYNFDSI----CRKCQCHGHVD 444
TG C CK+ G C++C+ G+YN C +C C G D
Sbjct: 464 DEPCTGPC------------VCKENVEGKACDRCKPGFYNLKEKNPRGCSECFCFGVSD 510
Score = 45.1 bits (105), Expect = 2e-04
Identities = 26/79 (32%), Positives = 39/79 (49%), Gaps = 3/79 (3%)
Query: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALS 300
C+C+ GS++ + C++T+GQC CR G GL C+ C+ L T C CD G L
Sbjct: 1509 CDCNPHGSVHGD-CDRTSGQCVCRLGASGLRCDECEPRHILMETD--CVSCDDECVGVLL 1565
Query: 301 IPCNSSGKCQCKVGVIGSI 319
+ G + + G I
Sbjct: 1566 NDLDEIGDAVLSLNLTGII 1584
>gi|21264602 laminin alpha 5 [Homo sapiens]
Length = 3695
Score = 142 bits (357), Expect = 1e-33
Identities = 99/321 (30%), Positives = 136/321 (42%), Gaps = 38/321 (11%)
Query: 165 PTPDLPSSSNSSVLPTPPATEAPSSPPPGHQWPVAKMPQKYLGKYACESNLKSKYLPLTQ 224
PTP + + VLP S K P+ +G+ C+ N + + L
Sbjct: 473 PTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPR--VGRCLCKPNFQGTHCELCA 530
Query: 225 PVMNLRVSEAVKTEYVCNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFYLNYT 284
P + C CS G + +RC+ TGQC CR G++G C+ C G++
Sbjct: 531 PGFYGPGCQP------CQCSSPGVAD-DRCDPDTGQCRCRVGFEGATCDRCAPGYF---H 580
Query: 285 SGLCQPCDCSPHGALSIPCNSSGKCQCKVGVIGSICDRCQDGYYGFSKNGCLPCQCNNRS 344
LCQ C CSP G L C+ +G+C C+ G CDRC+ GY+GF C C C+ R
Sbjct: 581 FPLCQLCGCSPAGTLPEGCDEAGRCLCQPEFAGPHCDRCRPGYHGFP--NCQACTCDPRG 638
Query: 345 ASCDALTGA--CLNCQENSKGNHCEECKEGFYQSPDATKECLRCPCSAVTST-GSCSIKS 401
A D L GA C+ G C+EC GF+ P C+ C CSA S +C +S
Sbjct: 639 A-LDQLCGAGGLCRCRPGYTGTACQECSPGFHGFP----SCVPCHCSAEGSLHAACDPRS 693
Query: 402 SELEPECDQCKDGYIGPNCNKCENGYYNFDSICRKCQCH----GHVDPVKTPKICKPESG 457
+ C+ G C+ C G YNF C CH VDP PE+
Sbjct: 694 GQC-----SCRPRVTGLRCDTCVPGAYNF-PYCEAGSCHPAGLAPVDP------ALPEAQ 741
Query: 458 ECINCLHNTTGFWCENCLEGY 478
C + G C+ C G+
Sbjct: 742 VPCMCRAHVEGPSCDRCKPGF 762
Score = 139 bits (349), Expect = 1e-32
Identities = 82/251 (32%), Positives = 112/251 (44%), Gaps = 39/251 (15%)
Query: 252 NRCNQTTGQC-ECRPGYQGLHCETCKEGFYLNYT--SGLCQPCDCSPHGALSIPCNSSGK 308
+RC +G C +C+ +G HCE C+ GF + S C C C LS+P N+ +
Sbjct: 1871 DRCLPGSGVCVDCQHNTEGAHCERCQAGFVSSRDDPSAPCVSCPCP----LSVPSNNFAE 1926
Query: 309 ----------CQCKVGVIGSICDRCQDGYYG---FSKNGCLPCQCNNRS------ASCDA 349
C CK G G+ C+RC G++G + C PC C+ + CD
Sbjct: 1927 GCVLRGGRTQCLCKPGYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDP 1986
Query: 350 LTGACLNCQENSKGNHCEECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKSSELEPECD 409
LTGAC C ++ G CE C GFY + C RC C+ T +C S
Sbjct: 1987 LTGACRGCLRHTTGPRCEICAPGFYGNALLPGNCTRCDCTP-CGTEACDPHSGHC----- 2040
Query: 410 QCKDGYIGPNCNKCENGYYNFDSI--CRKCQCHGHVDPVKTPKICKPESGECINCLHNTT 467
CK G G C++C+ G++ FD CR C C P C P+SG+C +C T
Sbjct: 2041 LCKAGVTGRRCDRCQEGHFGFDGCGGCRPCAC----GPAAEGSECHPQSGQC-HCRPGTM 2095
Query: 468 GFWCENCLEGY 478
G C C GY
Sbjct: 2096 GPQCRECAPGY 2106
Score = 130 bits (326), Expect = 5e-30
Identities = 71/210 (33%), Positives = 100/210 (47%), Gaps = 19/210 (9%)
Query: 294 SPHGALSIPCNSSGKCQCKVGVIGSICDRCQDGYY----GFSKNGCLPCQCNNRSASCDA 349
SP G ++ N C C G C C G+Y G C+PCQC+ S C
Sbjct: 1817 SPAGQGALASNVE-LCLCPASYRGDSCQECAPGFYRDVKGLFLGRCVPCQCHGHSDRCLP 1875
Query: 350 LTGACLNCQENSKGNHCEECKEGFYQS-PDATKECLRCPCSAVTSTGS----CSIKSSEL 404
+G C++CQ N++G HCE C+ GF S D + C+ CPC + + C ++
Sbjct: 1876 GSGVCVDCQHNTEGAHCERCQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGG-- 1933
Query: 405 EPECDQCKDGYIGPNCNKCENGYYN----FDSICRKCQCHGHVDPVKTPKICKPESGECI 460
+C CK GY G +C +C G++ S C+ C C G+ DP C P +G C
Sbjct: 1934 RTQC-LCKPGYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACR 1992
Query: 461 NCLHNTTGFWCENCLEGYVHD--LEGNCIK 488
CL +TTG CE C G+ + L GNC +
Sbjct: 1993 GCLRHTTGPRCEICAPGFYGNALLPGNCTR 2022
Score = 125 bits (314), Expect = 1e-28
Identities = 87/298 (29%), Positives = 114/298 (38%), Gaps = 74/298 (24%)
Query: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGF------YLNYTS--------- 285
CNC C TG+C CRP + G C+ C EGF Y +S
Sbjct: 429 CNCE--SDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVL 486
Query: 286 --GLCQPCDCSPHGALSIPCNSS---GKCQCKVGVIGSICDRCQDGYYGFSKNGCLPCQC 340
G CDCS G C G+C CK G+ C+ C G+YG GC PCQC
Sbjct: 487 PAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFYG---PGCQPCQC 543
Query: 341 NNRSAS---CDALTGACLNCQENSKGNHCEECKEGFYQSPDATKECLRCPCS-------A 390
++ + CD TG C C+ +G C+ C G++ P C C CS
Sbjct: 544 SSPGVADDRCDPDTGQC-RCRVGFEGATCDRCAPGYFHFP----LCQLCGCSPAGTLPEG 598
Query: 391 VTSTGSCSIKSSELEPECDQCKDGYIG-PNCN--------------------KCENGYYN 429
G C + P CD+C+ GY G PNC +C GY
Sbjct: 599 CDEAGRCLCQPEFAGPHCDRCRPGYHGFPNCQACTCDPRGALDQLCGAGGLCRCRPGYTG 658
Query: 430 FDSICRKCQCHGHVDPVKTP----------KICKPESGECINCLHNTTGFWCENCLEG 477
+ C++C H P P C P SG+C +C TG C+ C+ G
Sbjct: 659 --TACQECSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQC-SCRPRVTGLRCDTCVPG 713
Score = 125 bits (313), Expect = 2e-28
Identities = 90/326 (27%), Positives = 133/326 (40%), Gaps = 86/326 (26%)
Query: 240 VCNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGAL 299
+C CS G+L C++ G+C C+P + G HC+ C+ G++ + + CQ C C P GAL
Sbjct: 586 LCGCSPAGTLPEG-CDEA-GRCLCQPEFAGPHCDRCRPGYH-GFPN--CQACTCDPRGAL 640
Query: 300 SIPCNSSGKCQCKVGVIGSICDRCQDGYYGFSKNGCLPCQCNNRS---ASCDALTGAC-- 354
C + G C+C+ G G+ C C G++GF C+PC C+ A+CD +G C
Sbjct: 641 DQLCGAGGLCRCRPGYTGTACQECSPGFHGFPS--CVPCHCSAEGSLHAACDPRSGQCSC 698
Query: 355 ---------------------------------------------LNCQENSKGNHCEEC 369
C+ + +G C+ C
Sbjct: 699 RPRVTGLRCDTCVPGAYNFPYCEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRC 758
Query: 370 KEGFYQ-SPDATKECLRCPCS----------AVTSTGSCSIKSSELEPECDQCKDGYIGP 418
K GF+ SP + C RC C TG C K C CKDG+ G
Sbjct: 759 KPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFFGL 818
Query: 419 NCNKCENGYYNFDSICRKCQCH--GHVDPVKTPKICKPESGECINCLHNTTGFWC-ENCL 475
+ + Y+ CR C+C G + + C+P +G C C NT G C E
Sbjct: 819 D----QADYFG----CRSCRCDIGGALG-----QSCEPRTGVC-RCRPNTQGPTCSEPAR 864
Query: 476 EGYVHDLEGNCIKKEVILPTPEGSTI 501
+ Y+ DL ++ E TPEG +
Sbjct: 865 DHYLPDLHHLRLELEE-AATPEGHAV 889
Score = 103 bits (257), Expect = 5e-22
Identities = 72/232 (31%), Positives = 91/232 (39%), Gaps = 50/232 (21%)
Query: 265 PGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALSIPCNS-SGKCQCKVGVIGSICDRC 323
P L C L Y +G +PC C GA C G+C C VIG C RC
Sbjct: 1413 PSSSSLFCRNAAASLSLFYNNG-ARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRC 1471
Query: 324 QDGYYGFSKNGCLPCQCNNRSASCDALTGA-----------CLNCQENSKGNH----CEE 368
GY+GF C PC C R CD LTG CL CQ + G H CEE
Sbjct: 1472 ATGYWGFP--NCRPCDCGAR--LCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEE 1527
Query: 369 CK---EGFYQSPDATKECLRCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCEN 425
C G + D T + T +G C +C+ G C+ C
Sbjct: 1528 CNCSGPGIQELTDPTCD---------TDSGQC------------KCRPNVTGRRCDTCSP 1566
Query: 426 GYYNFDSICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEG 477
G++ + CR C CH + P +C P +G+C C N G C+ C G
Sbjct: 1567 GFHGYPR-CRPCDCH---EAGTAPGVCDPLTGQCY-CKENVQGPKCDQCSLG 1613
Score = 99.8 bits (247), Expect = 7e-21
Identities = 75/255 (29%), Positives = 110/255 (43%), Gaps = 51/255 (20%)
Query: 256 QTTGQC-ECRPGYQGLHCETCKEGFYLNYTSGL-----CQPCDCSPHGALSIPCNSSGKC 309
Q G C +C+ G++CE C GFY + L C+ C+C + +G+C
Sbjct: 388 QGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTCEDLTGRC 447
Query: 310 QCKVGVIGSICDRCQDGYYGF------------SKNGCLP------CQCN---NRSASC- 347
C+ G CD C +G+ GF ++ LP C C+ + +C
Sbjct: 448 YCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACR 507
Query: 348 -DALTGACLNCQENSKGNHCEECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKSSELEP 406
D G CL C+ N +G HCE C GFY C C CS S + +P
Sbjct: 508 KDPRVGRCL-CKPNFQGTHCELCAPGFY-----GPGCQPCQCS------SPGVADDRCDP 555
Query: 407 ECDQ--CKDGYIGPNCNKCENGYYNFDSICRKCQCHGHVDPVKT-PKICKPESGECINCL 463
+ Q C+ G+ G C++C GY++F +C+ C C P T P+ C E+G C+ C
Sbjct: 556 DTGQCRCRVGFEGATCDRCAPGYFHF-PLCQLCGC----SPAGTLPEGC-DEAGRCL-CQ 608
Query: 464 HNTTGFWCENCLEGY 478
G C+ C GY
Sbjct: 609 PEFAGPHCDRCRPGY 623
Score = 97.8 bits (242), Expect = 3e-20
Identities = 46/131 (35%), Positives = 63/131 (48%), Gaps = 6/131 (4%)
Query: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALS 300
C+C+ G+ C+ +G C C+ G G C+ C+EG + G C+PC C P S
Sbjct: 2023 CDCTPCGT---EACDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGCGGCRPCACGPAAEGS 2079
Query: 301 IPCNSSGKCQCKVGVIGSICDRCQDGYYGFSKNGCLPCQCNNRSASCDALTGACLNCQEN 360
SG+C C+ G +G C C GY+G + GC CQC CD TG C NC
Sbjct: 2080 ECHPQSGQCHCRPGTMGPQCRECAPGYWGLPEQGCRRCQC--PGGRCDPHTGRC-NCPPG 2136
Query: 361 SKGNHCEECKE 371
G C+ C +
Sbjct: 2137 LSGERCDTCSQ 2147
Score = 94.0 bits (232), Expect = 4e-19
Identities = 72/269 (26%), Positives = 103/269 (38%), Gaps = 57/269 (21%)
Query: 260 QCECRPGYQGLHCETCKEGFYLN-------YTSGLCQPCDCSPHG--------------- 297
QC C+ G C+ C GF ++ CQ C+C H
Sbjct: 321 QCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHATDCYYDPEVDRRRAS 380
Query: 298 -ALSIPCNSSGKC-QCKVGVIGSICDRCQDGYYGF------SKNGCLPCQCNN--RSASC 347
+L G C C+ G C+RC G+Y S + C C C + +C
Sbjct: 381 QSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTC 440
Query: 348 DALTGACLNCQENSKGNHCEECKEGF------YQSPDATK----------ECLRCPCSAV 391
+ LTG C C+ N G C+ C EGF Y +P ++ + + C CSA
Sbjct: 441 EDLTGRCY-CRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAA 499
Query: 392 TSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGYYNFDSICRKCQCHGHVDPVKTPKI 451
+ G+ K + C CK + G +C C G+Y C+ CQC P
Sbjct: 500 GTQGNACRKDPRV-GRC-LCKPNFQGTHCELCAPGFYG--PGCQPCQCS---SPGVADDR 552
Query: 452 CKPESGECINCLHNTTGFWCENCLEGYVH 480
C P++G+C C G C+ C GY H
Sbjct: 553 CDPDTGQC-RCRVGFEGATCDRCAPGYFH 580
Score = 93.2 bits (230), Expect = 7e-19
Identities = 64/227 (28%), Positives = 93/227 (40%), Gaps = 30/227 (13%)
Query: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALS 300
C C VG+ C GQC C G C C G++ + + C+PCDC
Sbjct: 1438 CGCHEVGATGPT-CEPFGGQCPCHAHVIGRDCSRCATGYW-GFPN--CRPCDCGARLCDE 1493
Query: 301 IPCNSSGKCQCKVGVIGSICDRCQDGYYGFSKN-GCLPCQCNN------RSASCDALTGA 353
+ +G+C C I C CQ +G GC C C+ +CD +G
Sbjct: 1494 L----TGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQ 1549
Query: 354 CLNCQENSKGNHCEECKEGFYQSPDATKECLRCPC-SAVTSTGSCSIKSSELEPECDQCK 412
C C+ N G C+ C GF+ P C C C A T+ G C L +C CK
Sbjct: 1550 C-KCRPNVTGRRCDTCSPGFHGYP----RCRPCDCHEAGTAPGVCD----PLTGQC-YCK 1599
Query: 413 DGYIGPNCNKCENGYYNFDSI----CRKCQCHGHVDPVKTPKICKPE 455
+ GP C++C G ++ D+ C +C C G + ++ + E
Sbjct: 1600 ENVQGPKCDQCSLGTFSLDAANPKGCTRCFCFGATERCRSSSYTRQE 1646
Score = 65.9 bits (159), Expect = 1e-10
Identities = 44/155 (28%), Positives = 60/155 (38%), Gaps = 22/155 (14%)
Query: 330 FSKNGCLPCQCNNRSAS---CDALTGACLNCQENSKGNHCEECKEGFYQSPDATKECLRC 386
F NG PC C+ A+ C+ G C C + G C C G++ P+ C C
Sbjct: 1430 FYNNGARPCGCHEVGATGPTCEPFGGQC-PCHAHVIGRDCSRCATGYWGFPN----CRPC 1484
Query: 387 PCSAVTS---TGSCSIKSSELEPECDQCKDGYIGPNCNKCENGYYNFDSICRKCQCHGHV 443
C A TG C + P+C C+ G C+ C +C C G
Sbjct: 1485 DCGARLCDELTGQCICPPRTIPPDCLLCQPQTFG--CHPLVG--------CEECNCSGPG 1534
Query: 444 DPVKTPKICKPESGECINCLHNTTGFWCENCLEGY 478
T C +SG+C C N TG C+ C G+
Sbjct: 1535 IQELTDPTCDTDSGQC-KCRPNVTGRRCDTCSPGF 1568
Score = 48.9 bits (115), Expect = 1e-05
Identities = 30/115 (26%), Positives = 46/115 (40%), Gaps = 22/115 (19%)
Query: 385 RCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGYY---------NFDSICR 435
RC C + +C C+ G C++C G+ N + C+
Sbjct: 299 RCVCHGHADACDAKDPTDPFRLQCT-CQHNTCGGTCDRCCPGFNQQPWKPATANSANECQ 357
Query: 436 KCQCHGHV-DPVKTPKICKPES-----------GECINCLHNTTGFWCENCLEGY 478
C C+GH D P++ + + G CI+C H+TTG CE CL G+
Sbjct: 358 SCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGF 412
Score = 39.7 bits (91), Expect = 0.009
Identities = 20/54 (37%), Positives = 25/54 (46%), Gaps = 3/54 (5%)
Query: 427 YYNFD--SICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGY 478
YY+ SI +C CHGH D P +C C HNT G C+ C G+
Sbjct: 288 YYSIKDISIGGRCVCHGHADACDAKDPTDPFRLQC-TCQHNTCGGTCDRCCPGF 340
>gi|145309326 laminin, gamma 1 precursor [Homo sapiens]
Length = 1609
Score = 139 bits (350), Expect = 8e-33
Identities = 66/192 (34%), Positives = 96/192 (50%), Gaps = 19/192 (9%)
Query: 301 IPCNSSGKCQCKVGVIGSICDRCQDGYYGFSKN-----GCLPCQCNNRSASCDALTGACL 355
+P C C VG G C+ C GY + N C+ C CN S +CD TG C
Sbjct: 682 VPATWVESCTCPVGYGGQFCEMCLSGYRRETPNLGPYSPCVLCACNGHSETCDPETGVC- 740
Query: 356 NCQENSKGNHCEECKEGFYQSPDA--TKECLRCPCSAVTSTGSCSIKSSELEPECDQCKD 413
NC++N+ G HCE+C +G+Y A + +C CPC +S C++ E C C
Sbjct: 741 NCRDNTAGPHCEKCSDGYYGDSTAGTSSDCQPCPCPGGSS---CAVVPKTKEVVCTNCPT 797
Query: 414 GYIGPNCNKCENGYYNFD-------SICRKCQCHGHVDPVKTPKICKPESGECINCLHNT 466
G G C C++GY+ +CR CQC ++DP C +GEC+ C++NT
Sbjct: 798 GTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGN-CNRLTGECLKCIYNT 856
Query: 467 TGFWCENCLEGY 478
GF+C+ C +G+
Sbjct: 857 AGFYCDRCKDGF 868
Score = 139 bits (350), Expect = 8e-33
Identities = 81/245 (33%), Positives = 114/245 (46%), Gaps = 33/245 (13%)
Query: 254 CNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGL---CQPCDCSPHGALSI-PCNSSGKC 309
C+ TG C CR G HCE C +G+Y + T+G CQPC C + ++ P C
Sbjct: 733 CDPETGVCNCRDNTAGPHCEKCSDGYYGDSTAGTSSDCQPCPCPGGSSCAVVPKTKEVVC 792
Query: 310 -QCKVGVIGSICDRCQDGYYG--FSKNG----CLPCQCN-----NRSASCDALTGACLNC 357
C G G C+ C DGY+G +NG C CQC+ N +C+ LTG CL C
Sbjct: 793 TNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNRLTGECLKC 852
Query: 358 QENSKGNHCEECKEGFY---QSPDATKECLRCPCS---AVTSTGSCSIKSSELEPECDQC 411
N+ G +C+ CK+GF+ +P+ +C C C+ + SC+ + + E C
Sbjct: 853 IYNTAGFYCDRCKDGFFGNPLAPNPADKCKACNCNLYGTMKQQSSCNPVTGQCE-----C 907
Query: 412 KDGYIGPNCNKCENGYYNFDS--ICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGF 469
G +C C+ G+YN S C +C CH T C +G+C C TG
Sbjct: 908 LPHVTGQDCGACDPGFYNLQSGQGCERCDCHA---LGSTNGQCDIRTGQC-ECQPGITGQ 963
Query: 470 WCENC 474
CE C
Sbjct: 964 HCERC 968
Score = 121 bits (303), Expect = 2e-27
Identities = 54/134 (40%), Positives = 77/134 (57%), Gaps = 5/134 (3%)
Query: 259 GQC-ECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALSIPCNSSGKCQCKVGVIG 317
G C C+ G HCE C+E F+ + C C CSP G+LS C+S G+C CK GV+G
Sbjct: 365 GHCTNCQDNTDGAHCERCRENFFRLGNNEACSSCHCSPVGSLSTQCDSYGRCSCKPGVMG 424
Query: 318 SICDRCQDGYYGFSKNGCLPCQCNNRSA--SCDALTGACLNCQENSKGNHCEECKEGFYQ 375
CDRCQ G++ ++ GC PC C+ + C+ TG C+ C++N +G +CE CK GF+
Sbjct: 425 DKCDRCQPGFHSLTEAGCRPCSCDPSGSIDECNIETGRCV-CKDNVEGFNCERCKPGFFN 483
Query: 376 SPDAT-KECLRCPC 388
+ + C C C
Sbjct: 484 LESSNPRGCTPCFC 497
Score = 117 bits (294), Expect = 2e-26
Identities = 57/170 (33%), Positives = 86/170 (50%), Gaps = 5/170 (2%)
Query: 241 CNCSVVGSLNV-NRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGAL 299
CNC++ G++ + CN TGQCEC P G C C GFY + C+ CDC G+
Sbjct: 884 CNCNLYGTMKQQSSCNPVTGQCECLPHVTGQDCGACDPGFYNLQSGQGCERCDCHALGST 943
Query: 300 SIPCN-SSGKCQCKVGVIGSICDRCQDGYYGFSKNGCLPCQCN-NRSASCDALTGACLNC 357
+ C+ +G+C+C+ G+ G C+RC+ ++GF GC PC C+ S S C
Sbjct: 944 NGQCDIRTGQCECQPGITGQHCERCEVNHFGFGPEGCKPCDCHPEGSLSLQCKDDGRCEC 1003
Query: 358 QENSKGNHCEECKEGFY--QSPDATKECLRCPCSAVTSTGSCSIKSSELE 405
+E GN C++C+E ++ +S +EC C +K ELE
Sbjct: 1004 REGFVGNRCDQCEENYFYNRSWPGCQECPACYRLVKDKVADHRVKLQELE 1053
Score = 114 bits (284), Expect = 4e-25
Identities = 76/244 (31%), Positives = 105/244 (43%), Gaps = 36/244 (14%)
Query: 261 CECRPGYQGLHCETCKEGFYLNYTSGL-----CQPCDCSPHGALSIPCNSSGKCQCKVGV 315
C C GY G CE C G Y T L C C C+ H P +G C C+
Sbjct: 690 CTCPVGYGGQFCEMCLSG-YRRETPNLGPYSPCVLCACNGHSETCDP--ETGVCNCRDNT 746
Query: 316 IGSICDRCQDGYYGFSKNG----CLPCQCNNRSASCDALTG----ACLNCQENSKGNHCE 367
G C++C DGYYG S G C PC C S SC + C NC + G CE
Sbjct: 747 AGPHCEKCSDGYYGDSTAGTSSDCQPCPCPGGS-SCAVVPKTKEVVCTNCPTGTTGKRCE 805
Query: 368 ECKEGFYQSP----DATKECLRCPCS---AVTSTGSCSIKSSELEPECDQCKDGYIGPNC 420
C +G++ P + C C CS + G+C + L EC +C G C
Sbjct: 806 LCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNC----NRLTGECLKCIYNTAGFYC 861
Query: 421 NKCENGYY------NFDSICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENC 474
++C++G++ N C+ C C+ + +K C P +G+C CL + TG C C
Sbjct: 862 DRCKDGFFGNPLAPNPADKCKACNCNLY-GTMKQQSSCNPVTGQC-ECLPHVTGQDCGAC 919
Query: 475 LEGY 478
G+
Sbjct: 920 DPGF 923
Score = 110 bits (276), Expect = 3e-24
Identities = 68/213 (31%), Positives = 96/213 (45%), Gaps = 42/213 (19%)
Query: 291 CDCSPHGALSIPCNSSGK--CQCKVGVIGSICDRCQDGYY--------GFSKNGCLPCQC 340
C C+ H + + N K C CK G C++C + S + CLPC C
Sbjct: 286 CKCNGHASECMK-NEFDKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDC 344
Query: 341 NNRSASC---------DALTGACLNCQENSKGNHCEECKEGFYQSPDATKECLRCPCSAV 391
N RS C G C NCQ+N+ G HCE C+E F++ + + C C CS V
Sbjct: 345 NGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFRLGN-NEACSSCHCSPV 403
Query: 392 TSTGSCSIKSSELEPECDQ-----CKDGYIGPNCNKCENGYYNF-DSICRKCQCHGHVDP 445
S L +CD CK G +G C++C+ G+++ ++ CR C C DP
Sbjct: 404 GS----------LSTQCDSYGRCSCKPGVMGDKCDRCQPGFHSLTEAGCRPCSC----DP 449
Query: 446 VKTPKICKPESGECINCLHNTTGFWCENCLEGY 478
+ C E+G C+ C N GF CE C G+
Sbjct: 450 SGSIDECNIETGRCV-CKDNVEGFNCERCKPGF 481
Score = 110 bits (274), Expect = 5e-24
Identities = 67/213 (31%), Positives = 105/213 (49%), Gaps = 23/213 (10%)
Query: 240 VCNCSVVGSLN-VNRCNQTTGQC-ECRPGYQGLHCETCKEGFYLN----YTSGLCQPCDC 293
+C CS N V CN+ TG+C +C G +C+ CK+GF+ N + C+ C+C
Sbjct: 827 LCQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKDGFFGNPLAPNPADKCKACNC 886
Query: 294 SPHGALS--IPCNS-SGKCQCKVGVIGSICDRCQDGYYGF-SKNGCLPCQCN---NRSAS 346
+ +G + CN +G+C+C V G C C G+Y S GC C C+ + +
Sbjct: 887 NLYGTMKQQSSCNPVTGQCECLPHVTGQDCGACDPGFYNLQSGQGCERCDCHALGSTNGQ 946
Query: 347 CDALTGACLNCQENSKGNHCEECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKSSELEP 406
CD TG C CQ G HCE C+ + + C C C GS S++ + +
Sbjct: 947 CDIRTGQC-ECQPGITGQHCERCEVNHFGF--GPEGCKPCDCHP---EGSLSLQCKD-DG 999
Query: 407 ECDQCKDGYIGPNCNKCENGYYNFDSI--CRKC 437
C+ C++G++G C++CE Y+ S C++C
Sbjct: 1000 RCE-CREGFVGNRCDQCEENYFYNRSWPGCQEC 1031
Score = 92.4 bits (228), Expect = 1e-18
Identities = 45/116 (38%), Positives = 67/116 (57%), Gaps = 8/116 (6%)
Query: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALS 300
C+CS VGSL+ +C+ + G+C C+PG G C+ C+ GF+ + T C+PC C P G++
Sbjct: 398 CHCSPVGSLST-QCD-SYGRCSCKPGVMGDKCDRCQPGFH-SLTEAGCRPCSCDPSGSID 454
Query: 301 IPCN-SSGKCQCKVGVIGSICDRCQDGYYGFSKN---GCLPCQCNNRSASCDALTG 352
CN +G+C CK V G C+RC+ G++ + GC PC C S+ C G
Sbjct: 455 -ECNIETGRCVCKDNVEGFNCERCKPGFFNLESSNPRGCTPCFCFGHSSVCTNAVG 509
Score = 90.1 bits (222), Expect = 6e-18
Identities = 57/205 (27%), Positives = 87/205 (42%), Gaps = 32/205 (15%)
Query: 261 CECRPGYQGLHCETCKEGFY-------LNYTSGLCQPCDCSPHGA-------LSIPCNSS 306
C C+ G+ CE C F ++ C PCDC+ L
Sbjct: 305 CNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCNGRSQECYFDPELYRSTGHG 364
Query: 307 GKC-QCKVGVIGSICDRCQDGYYGFSKN-GCLPCQCN---NRSASCDALTGACLNCQENS 361
G C C+ G+ C+RC++ ++ N C C C+ + S CD+ G C +C+
Sbjct: 365 GHCTNCQDNTDGAHCERCRENFFRLGNNEACSSCHCSPVGSLSTQCDSY-GRC-SCKPGV 422
Query: 362 KGNHCEECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNCN 421
G+ C+ C+ GF+ +A C C C S C+I++ CKD G NC
Sbjct: 423 MGDKCDRCQPGFHSLTEAG--CRPCSCDPSGSIDECNIETGRCV-----CKDNVEGFNCE 475
Query: 422 KCENGYYNFDSI----CRKCQCHGH 442
+C+ G++N +S C C C GH
Sbjct: 476 RCKPGFFNLESSNPRGCTPCFCFGH 500
Score = 63.5 bits (153), Expect = 6e-10
Identities = 42/135 (31%), Positives = 56/135 (41%), Gaps = 22/135 (16%)
Query: 357 CQENSKGNHCEECKEGFY-QSPDAT--KECLRCPCSAVTSTGSCSIKSSELEPECD--QC 411
C G CE C G+ ++P+ C+ C C+ + T +PE C
Sbjct: 692 CPVGYGGQFCEMCLSGYRRETPNLGPYSPCVLCACNGHSET---------CDPETGVCNC 742
Query: 412 KDGYIGPNCNKCENGYYN-----FDSICRKCQCHGHVDPVKTPKICKPESGECINCLHNT 466
+D GP+C KC +GYY S C+ C C G PK + C NC T
Sbjct: 743 RDNTAGPHCEKCSDGYYGDSTAGTSSDCQPCPCPGGSSCAVVPKT---KEVVCTNCPTGT 799
Query: 467 TGFWCENCLEGYVHD 481
TG CE C +GY D
Sbjct: 800 TGKRCELCDDGYFGD 814
Score = 55.5 bits (132), Expect = 2e-07
Identities = 38/113 (33%), Positives = 47/113 (41%), Gaps = 16/113 (14%)
Query: 411 CKDGYIGPNCNKCENGYYNFD------SICRKCQCHGHVDPVKTPKICKPESGECINCLH 464
C GY G C C +GY S C C C+GH + C PE+G C NC
Sbjct: 692 CPVGYGGQFCEMCLSGYRRETPNLGPYSPCVLCACNGHSET------CDPETGVC-NCRD 744
Query: 465 NTTGFWCENCLEGYVHDLEGNCIKKEVILPTPEGSTILV---SNASLTTSVPT 514
NT G CE C +GY D P P GS+ V + + T+ PT
Sbjct: 745 NTAGPHCEKCSDGYYGDSTAGTSSDCQPCPCPGGSSCAVVPKTKEVVCTNCPT 797
Score = 52.0 bits (123), Expect = 2e-06
Identities = 32/96 (33%), Positives = 47/96 (48%), Gaps = 9/96 (9%)
Query: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGL--CQPCDCSPHGA 298
C+C GS ++ CN TG+C C+ +G +CE CK GF+ +S C PC C H
Sbjct: 445 CSCDPSGS--IDECNIETGRCVCKDNVEGFNCERCKPGFFNLESSNPRGCTPCFCFGHS- 501
Query: 299 LSIPCNSSGKCQCKVGVIGSICDRCQDGYYGFSKNG 334
S+ N+ G V I S +DG+ ++G
Sbjct: 502 -SVCTNAVG---YSVYSISSTFQIDEDGWRAEQRDG 533
Score = 40.4 bits (93), Expect = 0.005
Identities = 28/106 (26%), Positives = 37/106 (34%), Gaps = 16/106 (15%)
Query: 385 RCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNKC---------ENGYYNFDSICR 435
RC C+ S +E + CK G +C KC S C
Sbjct: 285 RCKCNGHAS----ECMKNEFDKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECL 340
Query: 436 KCQCHGHVDPVK-TPKICKP--ESGECINCLHNTTGFWCENCLEGY 478
C C+G P++ + G C NC NT G CE C E +
Sbjct: 341 PCDCNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENF 386
>gi|110611156 laminin, gamma 3 precursor [Homo sapiens]
Length = 1575
Score = 134 bits (337), Expect = 3e-31
Identities = 104/363 (28%), Positives = 149/363 (41%), Gaps = 69/363 (19%)
Query: 140 LSTTTGPAPTTPVATTVPAPTTPRTPTPDLPSSSNSSVLPTPPATEAPSSPPPGHQWPVA 199
L + GP+P PV T T+ R P PP +
Sbjct: 637 LRVSPGPSPAGPVFLTEVRLTSAR-----------------------PGLSPPASWVEIC 673
Query: 200 KMPQKYLGKYACESNLKS--KYLPLTQPVMNLRVSEAVKTEYVCNCSVVGSLNVNRCNQT 257
P Y G++ CES + +P P + C C+ G+ C+
Sbjct: 674 SCPTGYTGQF-CESCAPGYKREMPQGGPYASC---------VPCTCNQHGT-----CDPN 718
Query: 258 TGQCECRPGYQGLHCETCKEGFYLNYTSGL---CQPCDCSPHGALS-IPCNSSGKC-QCK 312
TG C C +G CE C GFY N +G CQPC C A + IP + C C
Sbjct: 719 TGICVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCP 778
Query: 313 VGVIGSICDRCQDGYYGFS------KNGCLPCQCN-----NRSASCDALTGACLNCQENS 361
G G C+ C DG++G C CQC+ N +CD L+G CL C N+
Sbjct: 779 PGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNT 838
Query: 362 KGNHCEECKEGFYQS---PDATKECLRCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGP 418
G+HCE C+EGFY S P +C+ C C S S + + +C C
Sbjct: 839 TGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSV-SEQMPCDPVTGQC-SCLPHVTAR 896
Query: 419 NCNKCENGYYNFD--SICRKCQCHGHVDPVKTPK-ICKPESGECINCLHNTTGFWCENCL 475
+C++C G+++ CR C+CH P+ + + C P++G+C C TG C+ C
Sbjct: 897 DCSRCYPGFFDLQPGRGCRSCKCH----PLGSQEDQCHPKTGQC-TCRPGVTGQACDRCQ 951
Query: 476 EGY 478
G+
Sbjct: 952 LGF 954
Score = 115 bits (289), Expect = 9e-26
Identities = 63/166 (37%), Positives = 81/166 (48%), Gaps = 10/166 (6%)
Query: 232 SEAVKTEYVCNCS-----VVGSLNVNRCNQTTGQCE-CRPGYQGLHCETCKEGFYLNYTS 285
+EA CNCS + R G+C CR G HCE C+E FY
Sbjct: 318 AEAAHECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPR 377
Query: 286 GLCQPCDCSPHGALSIPCNSSGKCQCKVGVIGSICDRCQDGYYGFSKNGCLPCQCNNRSA 345
CQPCDC G+L + C+ +G C CK V G CDRC G++ S+ GC PC CN +
Sbjct: 378 MPCQPCDCQSAGSLHLQCDDTGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGS 437
Query: 346 --SCDALTGACLNCQENSKGNHCEECKEG-FYQSPDATKECLRCPC 388
+CD +G C C+EN +GN C+ C+ G F P C C C
Sbjct: 438 LDTCDPRSGRC-PCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFC 482
Score = 111 bits (278), Expect = 2e-24
Identities = 58/167 (34%), Positives = 85/167 (50%), Gaps = 9/167 (5%)
Query: 241 CNCSVVGSLNVNR-CNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGAL 299
C+C GS++ C+ TGQC C P C C GF+ C+ C C P G+
Sbjct: 866 CSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGSQ 925
Query: 300 SIPCN-SSGKCQCKVGVIGSICDRCQDGYYGFSKNGCLPCQCN---NRSASCDALTGACL 355
C+ +G+C C+ GV G CDRCQ G++GFS GC C+C+ SA C G C+
Sbjct: 926 EDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRACRCSPLGAASAQCHE-NGTCV 984
Query: 356 NCQENSKGNHCEECKEGFYQSPDATKECLRCP-CSAVTSTGSCSIKS 401
C+ +G C+ C + F+ + D T C +CP C A+ + +K+
Sbjct: 985 -CRPGFEGYKCDRCHDNFFLTADGT-HCQQCPSCYALVKEEAAKLKA 1029
Score = 82.8 bits (203), Expect = 9e-16
Identities = 59/224 (26%), Positives = 84/224 (37%), Gaps = 66/224 (29%)
Query: 291 CDCSPHGALSIPCNSSGKCQCKVGVIGSICDRCQDGYYGF-------------------- 330
C C+ H + +C V G + RCQ G
Sbjct: 271 CKCNGHAS-----------ECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAE 319
Query: 331 SKNGCLPCQCNNRSASC---------DALTGACLNCQENSKGNHCEECKEGFYQSPDATK 381
+ + CLPC C+ RS C G C +C++++ G HCE C+E FY D
Sbjct: 320 AAHECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHW-DPRM 378
Query: 382 ECLRCPCSAVTS-------TGSCSIKSSELEPECDQCKDGYIGPNCNKCENGYYNF-DSI 433
C C C + S TG+C+ CK G C++C G+++ +
Sbjct: 379 PCQPCDCQSAGSLHLQCDDTGTCA------------CKPTVTGWKCDRCLPGFHSLSEGG 426
Query: 434 CRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEG 477
CR C C +P + C P SG C C N G C+ C G
Sbjct: 427 CRPCTC----NPAGSLDTCDPRSGRC-PCKENVEGNLCDRCRPG 465
Score = 80.1 bits (196), Expect = 6e-15
Identities = 52/179 (29%), Positives = 76/179 (42%), Gaps = 23/179 (12%)
Query: 324 QDGYYG---FSKNGCLPCQCNNRSASC--DALTGACLNCQENSKGNHCEECKEGFYQSP- 377
Q YY FS G C+CN ++ C D CQ N+ G CE C F P
Sbjct: 256 QSYYYAVSDFSVGG--RCKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPW 313
Query: 378 -----DATKECLRCPCSAVTSTGSCS---IKSSELEPECDQCKDGYIGPNCNKCENGYYN 429
+A ECL C CS + + +S+ C C+D GP+C +C+ +Y+
Sbjct: 314 ARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYH 373
Query: 430 FD--SICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGYVHDLEGNC 486
+D C+ C C + + ++G C C TG+ C+ CL G+ EG C
Sbjct: 374 WDPRMPCQPCDCQS----AGSLHLQCDDTGTCA-CKPTVTGWKCDRCLPGFHSLSEGGC 427
Score = 79.7 bits (195), Expect = 8e-15
Identities = 56/205 (27%), Positives = 81/205 (39%), Gaps = 32/205 (15%)
Query: 261 CECRPGYQGLHCETCKEGFYLN-YTSGL------CQPCDCSPHGA-------LSIPCNSS 306
C C+ G CE C F + G C PC+CS L
Sbjct: 290 CRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHG 349
Query: 307 GKCQ-CKVGVIGSICDRCQDGYYGFS-KNGCLPCQCNNRSA---SCDALTGACLNCQENS 361
G+C C+ G C+RCQ+ +Y + + C PC C + + CD TG C C+
Sbjct: 350 GRCHHCRDHTAGPHCERCQENFYHWDPRMPCQPCDCQSAGSLHLQCDD-TGTCA-CKPTV 407
Query: 362 KGNHCEECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNCN 421
G C+ C GF+ + C C C+ S +C +S CK+ G C+
Sbjct: 408 TGWKCDRCLPGFHSLSEGG--CRPCTCNPAGSLDTCDPRSGRCP-----CKENVEGNLCD 460
Query: 422 KCENGYYNFD----SICRKCQCHGH 442
+C G +N + C C C+GH
Sbjct: 461 RCRPGTFNLQPHNPAGCSSCFCYGH 485
Score = 45.4 bits (106), Expect = 2e-04
Identities = 36/137 (26%), Positives = 53/137 (38%), Gaps = 25/137 (18%)
Query: 356 NCQENSKGNHCEECKEGFYQS-----PDATKECLRCPCS----AVTSTGSCSIKSSELEP 406
+C G CE C G+ + P A+ C+ C C+ +TG C P
Sbjct: 674 SCPTGYTGQFCESCAPGYKREMPQGGPYAS--CVPCTCNQHGTCDPNTGICVCSHHTEGP 731
Query: 407 ECDQCKDGYIGPNCNKCENGYYNFDSICRKCQCHGHVDPVKTPKICKPESGE--CINCLH 464
C++C G+ G N + C+ C C G ++ PES E C +C
Sbjct: 732 SCERCLPGFYG-------NPFAGQADDCQPCPCPG-----QSACTTIPESREVVCTHCPP 779
Query: 465 NTTGFWCENCLEGYVHD 481
G CE C +G+ D
Sbjct: 780 GQRGRRCEVCDDGFFGD 796
>gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
Length = 1816
Score = 132 bits (331), Expect = 1e-30
Identities = 66/185 (35%), Positives = 92/185 (49%), Gaps = 14/185 (7%)
Query: 313 VGVIGSICDRCQDGYYGFSKNGCLPCQCNNRSASCDALTGACLNCQENSKGNHCEECKEG 372
+G + ++C G++ C+PC CN S C +G C++CQ N+ G HCE+C +G
Sbjct: 57 LGRLPPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDG 116
Query: 373 FYQSP--DATKECLRCPCSA---VTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGY 427
+ A + C CPC SC K+ + C++ Y GPNC +C GY
Sbjct: 117 YIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNE---NYAGPNCERCAPGY 173
Query: 428 YN----FDSICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGYVHD-- 481
Y S C+KC C G+ DP + C +G+C NCL NTTGF CE C GY D
Sbjct: 174 YGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDAR 233
Query: 482 LEGNC 486
+ NC
Sbjct: 234 IAKNC 238
Score = 105 bits (262), Expect = 1e-22
Identities = 66/194 (34%), Positives = 85/194 (43%), Gaps = 29/194 (14%)
Query: 241 CNCSVVGSLNVNRCNQTTGQC-ECRPGYQGLHCETCKEGFYLNYTSG---LCQPCDCS-P 295
C+C+ N N C +G C C+ G HCE C +G+ + G CQPC C P
Sbjct: 82 CDCNG----NSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLP 137
Query: 296 HGA-LSIPC---NSSGKCQCKVGVIGSICDRCQDGYYG---FSKNGCLPCQCNNRS---- 344
H A + C N + +C C G C+RC GYYG + C C C+ S
Sbjct: 138 HLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNL 197
Query: 345 --ASCDALTGACLNCQENSKGNHCEECKEGFYQSPDATKECLRC-----PCSAVTSTGSC 397
CD +TG C NC N+ G CE C G+Y K C C PC +V TG C
Sbjct: 198 IFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGGPCDSV--TGEC 255
Query: 398 SIKSSELEPECDQC 411
+ E CD+C
Sbjct: 256 LEEGFEPPTGCDKC 269
Score = 98.2 bits (243), Expect = 2e-20
Identities = 71/220 (32%), Positives = 93/220 (42%), Gaps = 31/220 (14%)
Query: 273 ETCKEGFYLNYTSGLCQPCDCSPHGALSIPCNSSGKC-QCKVGVIGSICDRCQDGYYGFS 331
E C GF+ + SG C PCDC +G + + SG C C+ G C++C DGY G S
Sbjct: 65 EKCNAGFF-HTLSGECVPCDC--NGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDS 121
Query: 332 KNG----CLPCQC-----NNRSASCDALTGA--CLNCQENSKGNHCEECKEGFYQSPDAT 380
G C PC C N + SC GA C+ C EN G +CE C G+Y +P
Sbjct: 122 IRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCI-CNENYAGPNCERCAPGYYGNPLLI 180
Query: 381 -KECLRCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGYYNFDSI---CRK 436
C +C CS + E+ +C C G C +C GYY I C
Sbjct: 181 GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV 240
Query: 437 CQCHGHVDPVKTPKICKPESGECI-NCLHNTTGFWCENCL 475
C C G C +GEC+ TG C+ C+
Sbjct: 241 CNCGGGP--------CDSVTGECLEEGFEPPTG--CDKCV 270
>gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens]
Length = 1823
Score = 132 bits (331), Expect = 1e-30
Identities = 66/185 (35%), Positives = 92/185 (49%), Gaps = 14/185 (7%)
Query: 313 VGVIGSICDRCQDGYYGFSKNGCLPCQCNNRSASCDALTGACLNCQENSKGNHCEECKEG 372
+G + ++C G++ C+PC CN S C +G C++CQ N+ G HCE+C +G
Sbjct: 57 LGRLPPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDG 116
Query: 373 FYQSP--DATKECLRCPCSA---VTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGY 427
+ A + C CPC SC K+ + C++ Y GPNC +C GY
Sbjct: 117 YIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNE---NYAGPNCERCAPGY 173
Query: 428 YN----FDSICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGYVHD-- 481
Y S C+KC C G+ DP + C +G+C NCL NTTGF CE C GY D
Sbjct: 174 YGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDAR 233
Query: 482 LEGNC 486
+ NC
Sbjct: 234 IAKNC 238
Score = 100 bits (250), Expect = 3e-21
Identities = 66/203 (32%), Positives = 86/203 (42%), Gaps = 28/203 (13%)
Query: 241 CNCSVVGSLNVNRCNQTTGQC-ECRPGYQGLHCETCKEGFYLNYTSG---LCQPCDCS-P 295
C+C+ N N C +G C C+ G HCE C +G+ + G CQPC C P
Sbjct: 82 CDCNG----NSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLP 137
Query: 296 HGA-LSIPC---NSSGKCQCKVGVIGSICDRCQDGYYG---FSKNGCLPCQCNNRS---- 344
H A + C N + +C C G C+RC GYYG + C C C+ S
Sbjct: 138 HLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNL 197
Query: 345 --ASCDALTGACLNCQENSKGNHCEECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKSS 402
CD +TG C NC N+ G CE C G+Y K C C C G C +
Sbjct: 198 IFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGG----GPCDSVTG 253
Query: 403 ELEPECDQCKDGYIGP--NCNKC 423
E E + G P +C+KC
Sbjct: 254 ECLEEGFEPPTGMDCPTISCDKC 276
Score = 97.8 bits (242), Expect = 3e-20
Identities = 67/204 (32%), Positives = 87/204 (42%), Gaps = 28/204 (13%)
Query: 273 ETCKEGFYLNYTSGLCQPCDCSPHGALSIPCNSSGKC-QCKVGVIGSICDRCQDGYYGFS 331
E C GF+ + SG C PCDC +G + + SG C C+ G C++C DGY G S
Sbjct: 65 EKCNAGFF-HTLSGECVPCDC--NGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDS 121
Query: 332 KNG----CLPCQC-----NNRSASCDALTGA--CLNCQENSKGNHCEECKEGFYQSPDAT 380
G C PC C N + SC GA C+ C EN G +CE C G+Y +P
Sbjct: 122 IRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCI-CNENYAGPNCERCAPGYYGNPLLI 180
Query: 381 -KECLRCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGYYNFDSI---CRK 436
C +C CS + E+ +C C G C +C GYY I C
Sbjct: 181 GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV 240
Query: 437 CQCHGHVDPVKTPKICKPESGECI 460
C C G C +GEC+
Sbjct: 241 CNCGGGP--------CDSVTGECL 256
>gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
Length = 1816
Score = 132 bits (331), Expect = 1e-30
Identities = 66/185 (35%), Positives = 92/185 (49%), Gaps = 14/185 (7%)
Query: 313 VGVIGSICDRCQDGYYGFSKNGCLPCQCNNRSASCDALTGACLNCQENSKGNHCEECKEG 372
+G + ++C G++ C+PC CN S C +G C++CQ N+ G HCE+C +G
Sbjct: 57 LGRLPPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDG 116
Query: 373 FYQSP--DATKECLRCPCSA---VTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGY 427
+ A + C CPC SC K+ + C++ Y GPNC +C GY
Sbjct: 117 YIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNE---NYAGPNCERCAPGY 173
Query: 428 YN----FDSICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGYVHD-- 481
Y S C+KC C G+ DP + C +G+C NCL NTTGF CE C GY D
Sbjct: 174 YGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDAR 233
Query: 482 LEGNC 486
+ NC
Sbjct: 234 IAKNC 238
Score = 105 bits (262), Expect = 1e-22
Identities = 66/194 (34%), Positives = 85/194 (43%), Gaps = 29/194 (14%)
Query: 241 CNCSVVGSLNVNRCNQTTGQC-ECRPGYQGLHCETCKEGFYLNYTSG---LCQPCDCS-P 295
C+C+ N N C +G C C+ G HCE C +G+ + G CQPC C P
Sbjct: 82 CDCNG----NSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLP 137
Query: 296 HGA-LSIPC---NSSGKCQCKVGVIGSICDRCQDGYYG---FSKNGCLPCQCNNRS---- 344
H A + C N + +C C G C+RC GYYG + C C C+ S
Sbjct: 138 HLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNL 197
Query: 345 --ASCDALTGACLNCQENSKGNHCEECKEGFYQSPDATKECLRC-----PCSAVTSTGSC 397
CD +TG C NC N+ G CE C G+Y K C C PC +V TG C
Sbjct: 198 IFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGGPCDSV--TGEC 255
Query: 398 SIKSSELEPECDQC 411
+ E CD+C
Sbjct: 256 LEEGFEPPTGCDKC 269
Score = 98.2 bits (243), Expect = 2e-20
Identities = 71/220 (32%), Positives = 93/220 (42%), Gaps = 31/220 (14%)
Query: 273 ETCKEGFYLNYTSGLCQPCDCSPHGALSIPCNSSGKC-QCKVGVIGSICDRCQDGYYGFS 331
E C GF+ + SG C PCDC +G + + SG C C+ G C++C DGY G S
Sbjct: 65 EKCNAGFF-HTLSGECVPCDC--NGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDS 121
Query: 332 KNG----CLPCQC-----NNRSASCDALTGA--CLNCQENSKGNHCEECKEGFYQSPDAT 380
G C PC C N + SC GA C+ C EN G +CE C G+Y +P
Sbjct: 122 IRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCI-CNENYAGPNCERCAPGYYGNPLLI 180
Query: 381 -KECLRCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGYYNFDSI---CRK 436
C +C CS + E+ +C C G C +C GYY I C
Sbjct: 181 GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV 240
Query: 437 CQCHGHVDPVKTPKICKPESGECI-NCLHNTTGFWCENCL 475
C C G C +GEC+ TG C+ C+
Sbjct: 241 CNCGGGP--------CDSVTGECLEEGFEPPTG--CDKCV 270
>gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens]
Length = 3333
Score = 129 bits (323), Expect = 1e-29
Identities = 86/296 (29%), Positives = 125/296 (42%), Gaps = 55/296 (18%)
Query: 211 CESNLKSKYLPLTQPVMNLRVSEAVKTEYVCNCSVVGSLNVNRCNQTTGQCECRPGYQGL 270
CE K Y P PV +A C+C + + C Q +G+C C+P + G
Sbjct: 402 CEQCAKGYYRPYGVPV------DAPDGCIPCSCDPE---HADGCEQGSGRCHCKPNFHGD 452
Query: 271 HCETCKEGFYLNY-------------------TSGLCQPCDCSPHGALSIPCNSSGKCQC 311
+CE C G+Y N+ +G + CDC+ G L C++ G+C C
Sbjct: 453 NCEKCAIGYY-NFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCLC 511
Query: 312 KVGVIGSICDRCQDGYYGFSKNGCLPCQCN---NRSASCDALTGACLNCQENSKGNHCEE 368
+ GV G CD C+ G+Y F C C C+ + C ++TG C C+ G C+
Sbjct: 512 RPGVEGPRCDTCRSGFYSFPI--CQACWCSALGSYQMPCSSVTGQC-ECRPGVTGQRCDR 568
Query: 369 CKEGFYQSPDATKECLRC-PCSAVTST-GSCSIKSSELEPECDQCKDGYIGPNCNKCENG 426
C G Y P C P + S G C QCK GP C++C+
Sbjct: 569 CLSGAYDFPHCQGSSSACDPAGTINSNLGYC------------QCKLHVEGPTCSRCKLL 616
Query: 427 YYNFD----SICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGY 478
Y+N D S C +C+CH V C+ G+C +C + G C+ C +GY
Sbjct: 617 YWNLDKENPSGCSECKCH-KAGTVSGTGECRQGDGDC-HCKSHVGGDSCDTCEDGY 670
Score = 124 bits (311), Expect = 3e-28
Identities = 86/290 (29%), Positives = 131/290 (45%), Gaps = 44/290 (15%)
Query: 206 LGKYACESNLKSKYLPLTQPVMNLRVSEAVKTEYVCNCSVVGSLNVNRCNQTTGQCECRP 265
+G Y L+ P++ P V+ +K C+C++ G L G+C CRP
Sbjct: 459 IGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKG---CDCNLEGVLP--EICDAHGRCLCRP 513
Query: 266 GYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALSIPCNS-SGKCQCKVGVIGSICDRCQ 324
G +G C+TC+ GFY + +CQ C CS G+ +PC+S +G+C+C+ GV G CDRC
Sbjct: 514 GVEGPRCDTCRSGFY---SFPICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCL 570
Query: 325 DGYYGFSKNGCLPCQCNNRSASCDAL------TGACLNCQENSKGNHCEECKEGFY---- 374
G Y F C S++CD G C C+ + +G C CK ++
Sbjct: 571 SGAYDFP-------HCQGSSSACDPAGTINSNLGYC-QCKLHVEGPTCSRCKLLYWNLDK 622
Query: 375 QSPDATKECLRCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGYYNFDSI- 433
++P EC V+ TG C + + +C CK G +C+ CE+GY+ +
Sbjct: 623 ENPSGCSECKCHKAGTVSGTGECR----QGDGDC-HCKSHVGGDSCDTCEDGYFALEKSN 677
Query: 434 ---CRKCQCH--GHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGY 478
C+ CQC G + +C SG C C + G C+ Y
Sbjct: 678 YFGCQGCQCDIGGALS-----SMCSGPSGVC-QCREHVVGKVCQRPENNY 721
Score = 111 bits (277), Expect = 2e-24
Identities = 56/162 (34%), Positives = 74/162 (45%), Gaps = 17/162 (10%)
Query: 309 CQCKVGVIGSICDRCQDGYY----GFSKNGCLPCQCNNRSASCDALTGACLNCQENSKGN 364
C C G C C GYY G C+PC CN S C +G C+NCQ N+ G
Sbjct: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGE 1713
Query: 365 HCEECKEGFYQSPDATKECLRCPCSAVTSTGS-CSIKSSELEPECDQCKDGYIGPNCNKC 423
HCE C+EG+Y + C CPC S + C + ++ C CK GY G C +C
Sbjct: 1714 HCERCQEGYYGNA-VHGSCRACPCPHTNSFATGCVVNGGDV--RC-SCKAGYTGTQCERC 1769
Query: 424 ENGYY----NFDSICRKCQCHGHVDPVKTPKICKPESGECIN 461
GY+ F C+ C C+ + C P +G+CIN
Sbjct: 1770 APGYFGNPQKFGGSCQPCSCNSNGQLGS----CHPLTGDCIN 1807
Score = 108 bits (270), Expect = 2e-23
Identities = 55/148 (37%), Positives = 73/148 (49%), Gaps = 11/148 (7%)
Query: 254 CNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALSIPC----NSSGKC 309
C + TGQC C P CE C+ + + C+ C+CS G + SG+C
Sbjct: 1319 CEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQC 1378
Query: 310 QCKVGVIGSICDRCQDGYYGFSKNGCLPCQCNNRSAS---CDALTGACLNCQENSKGNHC 366
+CK + G CDRC G+Y F + C+PC CN CD TGACL C+EN +G C
Sbjct: 1379 RCKPRITGRQCDRCASGFYRFPE--CVPCNCNRDGTEPGVCDPGTGACL-CKENVEGTEC 1435
Query: 367 EECKEG-FYQSPDATKECLRCPCSAVTS 393
C+EG F+ P K C C C V +
Sbjct: 1436 NVCREGSFHLDPANLKGCTSCFCFGVNN 1463
Score = 108 bits (269), Expect = 2e-23
Identities = 68/199 (34%), Positives = 89/199 (44%), Gaps = 27/199 (13%)
Query: 290 PCDCSPHGALSIPCN-SSGKCQCKVGVIGSICDRCQDGYYGFSKNGCLPCQCNNRSASCD 348
PC+C P GA C+ G+C C+ VIG C RC G+YGF + C PC C R C+
Sbjct: 1265 PCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPR--CKPCSCGRR--LCE 1320
Query: 349 ALTGACLNCQENSKGNHCEECK-EGFYQSPDATKECLRCPCSAVTSTGSCSIKSSELEPE 407
+TG C C + CE C+ F P A C C CS + + PE
Sbjct: 1321 EMTGQC-RCPPRTVRPQCEVCETHSFSFHPMA--GCEGCNCSRRGTIEAAM-------PE 1370
Query: 408 CD------QCKDGYIGPNCNKCENGYYNFDSICRKCQCHGHVDPVKTPKICKPESGECIN 461
CD +CK G C++C +G+Y F C C C+ P +C P +G C+
Sbjct: 1371 CDRDSGQCRCKPRITGRQCDRCASGFYRFPE-CVPCNCN---RDGTEPGVCDPGTGACL- 1425
Query: 462 CLHNTTGFWCENCLEGYVH 480
C N G C C EG H
Sbjct: 1426 CKENVEGTECNVCREGSFH 1444
Score = 98.2 bits (243), Expect = 2e-20
Identities = 49/140 (35%), Positives = 72/140 (51%), Gaps = 15/140 (10%)
Query: 241 CNCSVVGSLNVNRCNQTTGQC-ECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGAL 299
CNC+ + N+C +G C C+ G HCE C+EG+Y N G C+ C C +
Sbjct: 1687 CNCNG----HSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRACPCPHTNSF 1742
Query: 300 SIPCNSSG---KCQCKVGVIGSICDRCQDGYYGFSK---NGCLPCQCNNRS--ASCDALT 351
+ C +G +C CK G G+ C+RC GY+G + C PC CN+ SC LT
Sbjct: 1743 ATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLT 1802
Query: 352 GACLNCQ--ENSKGNHCEEC 369
G C+N + ++S C++C
Sbjct: 1803 GDCINQEPKDSSPAEECDDC 1822
Score = 95.5 bits (236), Expect = 1e-19
Identities = 60/213 (28%), Positives = 85/213 (39%), Gaps = 30/213 (14%)
Query: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALS 300
C C G+ + C+ GQC C+P G C C G +Y C+PC C
Sbjct: 1266 CECHPTGATGPH-CSPEGGQCPCQPNVIGRQCTRCATG---HYGFPRCKPCSCGRR---- 1317
Query: 301 IPCNSSGKCQCKVGVIGSICDRCQDGYYGF-SKNGCLPCQCNNRSA------SCDALTGA 353
+ +G+C+C + C+ C+ + F GC C C+ R CD +G
Sbjct: 1318 LCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQ 1377
Query: 354 CLNCQENSKGNHCEECKEGFYQSPDATKECLRCPCSA-VTSTGSCSIKSSELEPECDQCK 412
C C+ G C+ C GFY+ P EC+ C C+ T G C + CK
Sbjct: 1378 C-RCKPRITGRQCDRCASGFYRFP----ECVPCNCNRDGTEPGVCDPGTGAC-----LCK 1427
Query: 413 DGYIGPNCNKCENGYYNFDSI----CRKCQCHG 441
+ G CN C G ++ D C C C G
Sbjct: 1428 ENVEGTECNVCREGSFHLDPANLKGCTSCFCFG 1460
Score = 91.7 bits (226), Expect = 2e-18
Identities = 66/232 (28%), Positives = 91/232 (39%), Gaps = 55/232 (23%)
Query: 291 CDCSPHGALSIPCNSSG-----KCQCKVGVIGSICDRCQDGYYGF--------SKNGCLP 337
C C+ H + CN + +C+C+ G CDRC GY + C
Sbjct: 299 CVCNGHAEV---CNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEA 355
Query: 338 CQCNNRSASCD------------------ALTGACLNCQENSKGNHCEECKEGFYQ---- 375
C C+ +++C A G C+NCQ N+ G +CE+C +G+Y+
Sbjct: 356 CNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGV 415
Query: 376 SPDATKECLRCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGYYNFDSICR 435
DA C+ C C + G C S CK + G NC KC GYYNF R
Sbjct: 416 PVDAPDGCIPCSCDPEHADG-CEQGSGRC-----HCKPNFHGDNCEKCAIGYYNFPFCLR 469
Query: 436 KCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGYVHDLEGNCI 487
+ PV TP P +G+ C N G E C D G C+
Sbjct: 470 I-----PIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEIC------DAHGRCL 510
Score = 91.3 bits (225), Expect = 2e-18
Identities = 56/172 (32%), Positives = 78/172 (45%), Gaps = 24/172 (13%)
Query: 261 CECRPGYQGLHCETCKEGFYLNYT---SGLCQPCDCSPHGALSIPC-NSSGKC-QCKVGV 315
C C P Y G C+ C G+Y ++ +G C PC+C+ H S C + SG C C+
Sbjct: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGH---SNQCQDGSGICVNCQHNT 1710
Query: 316 IGSICDRCQDGYYGFSKNG-CLPCQC---NNRSASCDALTG-ACLNCQENSKGNHCEECK 370
G C+RCQ+GYYG + +G C C C N+ + C G +C+ G CE C
Sbjct: 1711 AGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCA 1770
Query: 371 EGFYQSPDA-TKECLRCPCSAVTSTGSC----------SIKSSELEPECDQC 411
G++ +P C C C++ GSC K S ECD C
Sbjct: 1771 PGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 1822
Score = 83.6 bits (205), Expect = 5e-16
Identities = 55/189 (29%), Positives = 74/189 (39%), Gaps = 57/189 (30%)
Query: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFY----LNYTSGLCQP------ 290
C CS +GS + C+ TGQCECRPG G C+ C G Y +S C P
Sbjct: 536 CWCSALGSYQMP-CSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINS 594
Query: 291 ----CDC----------------------SPHGALSIPCNSSGK-------------CQC 311
C C +P G C+ +G C C
Sbjct: 595 NLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHC 654
Query: 312 KVGVIGSICDRCQDGYYGFSKN---GCLPCQCN---NRSASCDALTGACLNCQENSKGNH 365
K V G CD C+DGY+ K+ GC CQC+ S+ C +G C C+E+ G
Sbjct: 655 KSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVC-QCREHVVGKV 713
Query: 366 CEECKEGFY 374
C+ + +Y
Sbjct: 714 CQRPENNYY 722
Score = 65.5 bits (158), Expect = 1e-10
Identities = 37/101 (36%), Positives = 47/101 (46%), Gaps = 15/101 (14%)
Query: 392 TSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGYYN-----FDSICRKCQCHGHVDPV 446
+ TGS I L E C Y G +C C GYY + C C C+GH +
Sbjct: 1640 SDTGSGRIA---LAVEICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQ- 1695
Query: 447 KTPKICKPESGECINCLHNTTGFWCENCLEGYV-HDLEGNC 486
C+ SG C+NC HNT G CE C EGY + + G+C
Sbjct: 1696 -----CQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSC 1731
Score = 55.8 bits (133), Expect = 1e-07
Identities = 35/126 (27%), Positives = 49/126 (38%), Gaps = 12/126 (9%)
Query: 357 CQENSKGNHCEECKEGFYQSPDA--TKECLRCPCSAVTSTGSCSIKSSELEPECDQCKDG 414
C G+ C+ C G+Y+ T C+ C C+ + C S C C+
Sbjct: 1656 CPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNG--HSNQCQDGSGI----CVNCQHN 1709
Query: 415 YIGPNCNKCENGYYN--FDSICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCE 472
G +C +C+ GYY CR C C H + T + C +C TG CE
Sbjct: 1710 TAGEHCERCQEGYYGNAVHGSCRACPCP-HTNSFATGCVVNGGDVRC-SCKAGYTGTQCE 1767
Query: 473 NCLEGY 478
C GY
Sbjct: 1768 RCAPGY 1773
>gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens]
Length = 3277
Score = 129 bits (323), Expect = 1e-29
Identities = 86/296 (29%), Positives = 125/296 (42%), Gaps = 55/296 (18%)
Query: 211 CESNLKSKYLPLTQPVMNLRVSEAVKTEYVCNCSVVGSLNVNRCNQTTGQCECRPGYQGL 270
CE K Y P PV +A C+C + + C Q +G+C C+P + G
Sbjct: 402 CEQCAKGYYRPYGVPV------DAPDGCIPCSCDPE---HADGCEQGSGRCHCKPNFHGD 452
Query: 271 HCETCKEGFYLNY-------------------TSGLCQPCDCSPHGALSIPCNSSGKCQC 311
+CE C G+Y N+ +G + CDC+ G L C++ G+C C
Sbjct: 453 NCEKCAIGYY-NFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCLC 511
Query: 312 KVGVIGSICDRCQDGYYGFSKNGCLPCQCN---NRSASCDALTGACLNCQENSKGNHCEE 368
+ GV G CD C+ G+Y F C C C+ + C ++TG C C+ G C+
Sbjct: 512 RPGVEGPRCDTCRSGFYSFPI--CQACWCSALGSYQMPCSSVTGQC-ECRPGVTGQRCDR 568
Query: 369 CKEGFYQSPDATKECLRC-PCSAVTST-GSCSIKSSELEPECDQCKDGYIGPNCNKCENG 426
C G Y P C P + S G C QCK GP C++C+
Sbjct: 569 CLSGAYDFPHCQGSSSACDPAGTINSNLGYC------------QCKLHVEGPTCSRCKLL 616
Query: 427 YYNFD----SICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGY 478
Y+N D S C +C+CH V C+ G+C +C + G C+ C +GY
Sbjct: 617 YWNLDKENPSGCSECKCH-KAGTVSGTGECRQGDGDC-HCKSHVGGDSCDTCEDGY 670
Score = 124 bits (311), Expect = 3e-28
Identities = 86/290 (29%), Positives = 131/290 (45%), Gaps = 44/290 (15%)
Query: 206 LGKYACESNLKSKYLPLTQPVMNLRVSEAVKTEYVCNCSVVGSLNVNRCNQTTGQCECRP 265
+G Y L+ P++ P V+ +K C+C++ G L G+C CRP
Sbjct: 459 IGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKG---CDCNLEGVLP--EICDAHGRCLCRP 513
Query: 266 GYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALSIPCNS-SGKCQCKVGVIGSICDRCQ 324
G +G C+TC+ GFY + +CQ C CS G+ +PC+S +G+C+C+ GV G CDRC
Sbjct: 514 GVEGPRCDTCRSGFY---SFPICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCL 570
Query: 325 DGYYGFSKNGCLPCQCNNRSASCDAL------TGACLNCQENSKGNHCEECKEGFY---- 374
G Y F C S++CD G C C+ + +G C CK ++
Sbjct: 571 SGAYDFP-------HCQGSSSACDPAGTINSNLGYC-QCKLHVEGPTCSRCKLLYWNLDK 622
Query: 375 QSPDATKECLRCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGYYNFDSI- 433
++P EC V+ TG C + + +C CK G +C+ CE+GY+ +
Sbjct: 623 ENPSGCSECKCHKAGTVSGTGECR----QGDGDC-HCKSHVGGDSCDTCEDGYFALEKSN 677
Query: 434 ---CRKCQCH--GHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGY 478
C+ CQC G + +C SG C C + G C+ Y
Sbjct: 678 YFGCQGCQCDIGGALS-----SMCSGPSGVC-QCREHVVGKVCQRPENNY 721
Score = 111 bits (277), Expect = 2e-24
Identities = 56/162 (34%), Positives = 74/162 (45%), Gaps = 17/162 (10%)
Query: 309 CQCKVGVIGSICDRCQDGYY----GFSKNGCLPCQCNNRSASCDALTGACLNCQENSKGN 364
C C G C C GYY G C+PC CN S C +G C+NCQ N+ G
Sbjct: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGE 1713
Query: 365 HCEECKEGFYQSPDATKECLRCPCSAVTSTGS-CSIKSSELEPECDQCKDGYIGPNCNKC 423
HCE C+EG+Y + C CPC S + C + ++ C CK GY G C +C
Sbjct: 1714 HCERCQEGYYGNA-VHGSCRACPCPHTNSFATGCVVNGGDV--RC-SCKAGYTGTQCERC 1769
Query: 424 ENGYY----NFDSICRKCQCHGHVDPVKTPKICKPESGECIN 461
GY+ F C+ C C+ + C P +G+CIN
Sbjct: 1770 APGYFGNPQKFGGSCQPCSCNSNGQLGS----CHPLTGDCIN 1807
Score = 108 bits (270), Expect = 2e-23
Identities = 55/148 (37%), Positives = 73/148 (49%), Gaps = 11/148 (7%)
Query: 254 CNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALSIPC----NSSGKC 309
C + TGQC C P CE C+ + + C+ C+CS G + SG+C
Sbjct: 1319 CEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQC 1378
Query: 310 QCKVGVIGSICDRCQDGYYGFSKNGCLPCQCNNRSAS---CDALTGACLNCQENSKGNHC 366
+CK + G CDRC G+Y F + C+PC CN CD TGACL C+EN +G C
Sbjct: 1379 RCKPRITGRQCDRCASGFYRFPE--CVPCNCNRDGTEPGVCDPGTGACL-CKENVEGTEC 1435
Query: 367 EECKEG-FYQSPDATKECLRCPCSAVTS 393
C+EG F+ P K C C C V +
Sbjct: 1436 NVCREGSFHLDPANLKGCTSCFCFGVNN 1463
Score = 108 bits (269), Expect = 2e-23
Identities = 68/199 (34%), Positives = 89/199 (44%), Gaps = 27/199 (13%)
Query: 290 PCDCSPHGALSIPCN-SSGKCQCKVGVIGSICDRCQDGYYGFSKNGCLPCQCNNRSASCD 348
PC+C P GA C+ G+C C+ VIG C RC G+YGF + C PC C R C+
Sbjct: 1265 PCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPR--CKPCSCGRR--LCE 1320
Query: 349 ALTGACLNCQENSKGNHCEECK-EGFYQSPDATKECLRCPCSAVTSTGSCSIKSSELEPE 407
+TG C C + CE C+ F P A C C CS + + PE
Sbjct: 1321 EMTGQC-RCPPRTVRPQCEVCETHSFSFHPMA--GCEGCNCSRRGTIEAAM-------PE 1370
Query: 408 CD------QCKDGYIGPNCNKCENGYYNFDSICRKCQCHGHVDPVKTPKICKPESGECIN 461
CD +CK G C++C +G+Y F C C C+ P +C P +G C+
Sbjct: 1371 CDRDSGQCRCKPRITGRQCDRCASGFYRFPE-CVPCNCN---RDGTEPGVCDPGTGACL- 1425
Query: 462 CLHNTTGFWCENCLEGYVH 480
C N G C C EG H
Sbjct: 1426 CKENVEGTECNVCREGSFH 1444
Score = 98.2 bits (243), Expect = 2e-20
Identities = 49/140 (35%), Positives = 72/140 (51%), Gaps = 15/140 (10%)
Query: 241 CNCSVVGSLNVNRCNQTTGQC-ECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGAL 299
CNC+ + N+C +G C C+ G HCE C+EG+Y N G C+ C C +
Sbjct: 1687 CNCNG----HSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRACPCPHTNSF 1742
Query: 300 SIPCNSSG---KCQCKVGVIGSICDRCQDGYYGFSK---NGCLPCQCNNRS--ASCDALT 351
+ C +G +C CK G G+ C+RC GY+G + C PC CN+ SC LT
Sbjct: 1743 ATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLT 1802
Query: 352 GACLNCQ--ENSKGNHCEEC 369
G C+N + ++S C++C
Sbjct: 1803 GDCINQEPKDSSPAEECDDC 1822
Score = 95.5 bits (236), Expect = 1e-19
Identities = 60/213 (28%), Positives = 85/213 (39%), Gaps = 30/213 (14%)
Query: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALS 300
C C G+ + C+ GQC C+P G C C G +Y C+PC C
Sbjct: 1266 CECHPTGATGPH-CSPEGGQCPCQPNVIGRQCTRCATG---HYGFPRCKPCSCGRR---- 1317
Query: 301 IPCNSSGKCQCKVGVIGSICDRCQDGYYGF-SKNGCLPCQCNNRSA------SCDALTGA 353
+ +G+C+C + C+ C+ + F GC C C+ R CD +G
Sbjct: 1318 LCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQ 1377
Query: 354 CLNCQENSKGNHCEECKEGFYQSPDATKECLRCPCSA-VTSTGSCSIKSSELEPECDQCK 412
C C+ G C+ C GFY+ P EC+ C C+ T G C + CK
Sbjct: 1378 C-RCKPRITGRQCDRCASGFYRFP----ECVPCNCNRDGTEPGVCDPGTGAC-----LCK 1427
Query: 413 DGYIGPNCNKCENGYYNFDSI----CRKCQCHG 441
+ G CN C G ++ D C C C G
Sbjct: 1428 ENVEGTECNVCREGSFHLDPANLKGCTSCFCFG 1460
Score = 91.7 bits (226), Expect = 2e-18
Identities = 66/232 (28%), Positives = 91/232 (39%), Gaps = 55/232 (23%)
Query: 291 CDCSPHGALSIPCNSSG-----KCQCKVGVIGSICDRCQDGYYGF--------SKNGCLP 337
C C+ H + CN + +C+C+ G CDRC GY + C
Sbjct: 299 CVCNGHAEV---CNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEA 355
Query: 338 CQCNNRSASCD------------------ALTGACLNCQENSKGNHCEECKEGFYQ---- 375
C C+ +++C A G C+NCQ N+ G +CE+C +G+Y+
Sbjct: 356 CNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGV 415
Query: 376 SPDATKECLRCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGYYNFDSICR 435
DA C+ C C + G C S CK + G NC KC GYYNF R
Sbjct: 416 PVDAPDGCIPCSCDPEHADG-CEQGSGRC-----HCKPNFHGDNCEKCAIGYYNFPFCLR 469
Query: 436 KCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGYVHDLEGNCI 487
+ PV TP P +G+ C N G E C D G C+
Sbjct: 470 I-----PIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEIC------DAHGRCL 510
Score = 91.3 bits (225), Expect = 2e-18
Identities = 56/172 (32%), Positives = 78/172 (45%), Gaps = 24/172 (13%)
Query: 261 CECRPGYQGLHCETCKEGFYLNYT---SGLCQPCDCSPHGALSIPC-NSSGKC-QCKVGV 315
C C P Y G C+ C G+Y ++ +G C PC+C+ H S C + SG C C+
Sbjct: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGH---SNQCQDGSGICVNCQHNT 1710
Query: 316 IGSICDRCQDGYYGFSKNG-CLPCQC---NNRSASCDALTG-ACLNCQENSKGNHCEECK 370
G C+RCQ+GYYG + +G C C C N+ + C G +C+ G CE C
Sbjct: 1711 AGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCA 1770
Query: 371 EGFYQSPDA-TKECLRCPCSAVTSTGSC----------SIKSSELEPECDQC 411
G++ +P C C C++ GSC K S ECD C
Sbjct: 1771 PGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 1822
Score = 83.6 bits (205), Expect = 5e-16
Identities = 55/189 (29%), Positives = 74/189 (39%), Gaps = 57/189 (30%)
Query: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFY----LNYTSGLCQP------ 290
C CS +GS + C+ TGQCECRPG G C+ C G Y +S C P
Sbjct: 536 CWCSALGSYQMP-CSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINS 594
Query: 291 ----CDC----------------------SPHGALSIPCNSSGK-------------CQC 311
C C +P G C+ +G C C
Sbjct: 595 NLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHC 654
Query: 312 KVGVIGSICDRCQDGYYGFSKN---GCLPCQCN---NRSASCDALTGACLNCQENSKGNH 365
K V G CD C+DGY+ K+ GC CQC+ S+ C +G C C+E+ G
Sbjct: 655 KSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVC-QCREHVVGKV 713
Query: 366 CEECKEGFY 374
C+ + +Y
Sbjct: 714 CQRPENNYY 722
Score = 65.5 bits (158), Expect = 1e-10
Identities = 37/101 (36%), Positives = 47/101 (46%), Gaps = 15/101 (14%)
Query: 392 TSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGYYN-----FDSICRKCQCHGHVDPV 446
+ TGS I L E C Y G +C C GYY + C C C+GH +
Sbjct: 1640 SDTGSGRIA---LAVEICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQ- 1695
Query: 447 KTPKICKPESGECINCLHNTTGFWCENCLEGYV-HDLEGNC 486
C+ SG C+NC HNT G CE C EGY + + G+C
Sbjct: 1696 -----CQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSC 1731
Score = 55.8 bits (133), Expect = 1e-07
Identities = 35/126 (27%), Positives = 49/126 (38%), Gaps = 12/126 (9%)
Query: 357 CQENSKGNHCEECKEGFYQSPDA--TKECLRCPCSAVTSTGSCSIKSSELEPECDQCKDG 414
C G+ C+ C G+Y+ T C+ C C+ + C S C C+
Sbjct: 1656 CPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNG--HSNQCQDGSGI----CVNCQHN 1709
Query: 415 YIGPNCNKCENGYYN--FDSICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCE 472
G +C +C+ GYY CR C C H + T + C +C TG CE
Sbjct: 1710 TAGEHCERCQEGYYGNAVHGSCRACPCP-HTNSFATGCVVNGGDVRC-SCKAGYTGTQCE 1767
Query: 473 NCLEGY 478
C GY
Sbjct: 1768 RCAPGY 1773
>gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens]
Length = 1111
Score = 120 bits (302), Expect = 3e-27
Identities = 64/186 (34%), Positives = 83/186 (44%), Gaps = 18/186 (9%)
Query: 308 KCQCKVGVIGSICDRCQDGYYGFSKN-----GCLPCQCNNRSASCDALTGACLNCQENSK 362
+C C VG G C C GY S C+PC C A CD TG C + EN
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA-CDPDTGDCYSGDENPD 439
Query: 363 GNHCEECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNK 422
C +C GFY P + C CPC + SCS+ E C+ C G G C
Sbjct: 440 -IECADCPIGFYNDPHDPRSCKPCPCH---NGFSCSVMPETEEVVCNNCPPGVTGARCEL 495
Query: 423 CENGYYNFD-------SICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCL 475
C +GY+ C+ CQC+ +VDP + C +G C+ C+HNT G +C+ C
Sbjct: 496 CADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGN-CDRLTGRCLKCIHNTAGIYCDQCK 554
Query: 476 EGYVHD 481
GY D
Sbjct: 555 AGYFGD 560
Score = 110 bits (276), Expect = 3e-24
Identities = 68/204 (33%), Positives = 95/204 (46%), Gaps = 41/204 (20%)
Query: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFYLN-YTSGLCQPCDCSPHGAL 299
CNC G+ C+ TG C + C C GFY + + C+PC C +
Sbjct: 416 CNCQGGGA-----CDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSC 470
Query: 300 SI-PCNSSGKCQ-CKVGVIGSICDRCQDGYYG--FSKNG----CLPCQCNNR-----SAS 346
S+ P C C GV G+ C+ C DGY+G F ++G C PCQCNN S +
Sbjct: 471 SVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGN 530
Query: 347 CDALTGACLNCQENSKGNHCEECKEGFY---QSPDATKECLRCPCSAV-------TSTGS 396
CD LTG CL C N+ G +C++CK G++ +P+ +C C C+ + S G+
Sbjct: 531 CDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGT 590
Query: 397 CSIKSSELEPECDQCKDGYIGPNC 420
C CK G+ GPNC
Sbjct: 591 C------------VCKPGFGGPNC 602
Score = 106 bits (264), Expect = 7e-23
Identities = 64/205 (31%), Positives = 92/205 (44%), Gaps = 33/205 (16%)
Query: 201 MPQKYLGKYACESNLKSKYLPLTQPVMNLRVSEAVKTEYVCNCS-----VVGSLNVNRCN 255
MP +LG C S L L + A VC+C+ + ++R
Sbjct: 1 MPALWLGCCLCFSLL-------------LPAARATSRREVCDCNGKSRQCIFDRELHRQT 47
Query: 256 QTTGQC-ECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALSIPCNSSGKCQCKVG 314
+C C G+HCE CK GFY + C PC+C+ G+LS C++SG+C CK G
Sbjct: 48 GNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRCSCKPG 107
Query: 315 VIGSICDRCQDGYYGFSKNGCL--------PCQCN--NRSASCDALTGACLNCQENSKGN 364
V G+ CDRC G++ + GC C C+ + CDA G C+ C+ G
Sbjct: 108 VTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDA--GRCV-CKPAVTGE 164
Query: 365 HCEECKEGFYQSPDATKE-CLRCPC 388
C+ C+ G+Y E C +C C
Sbjct: 165 RCDRCRSGYYNLDGGNPEGCTQCFC 189
Score = 95.1 bits (235), Expect = 2e-19
Identities = 49/117 (41%), Positives = 66/117 (56%), Gaps = 14/117 (11%)
Query: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGLCQP-------CDC 293
CNC+ GSL+ RC+ + G+C C+PG G C+ C GF++ +G Q CDC
Sbjct: 84 CNCNSKGSLSA-RCDNS-GRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDC 141
Query: 294 SPHGALSIPCNSSGKCQCKVGVIGSICDRCQDGYY---GFSKNGCLPCQCNNRSASC 347
P G ++ PC++ G+C CK V G CDRC+ GYY G + GC C C SASC
Sbjct: 142 DPAG-IAGPCDA-GRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSASC 196
Score = 80.5 bits (197), Expect = 4e-15
Identities = 60/181 (33%), Positives = 81/181 (44%), Gaps = 41/181 (22%)
Query: 338 CQCNNRSASC------DALTG---ACLNCQENSKGNHCEECKEGFYQSPDATKECLRCPC 388
C CN +S C TG CLNC +N+ G HCE+CK GFY+ + + CL C C
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDR-CLPCNC 86
Query: 389 SAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGYYNF-DSICR--------KCQC 439
+ S GS S + C CK G G C++C G++ D+ C KC C
Sbjct: 87 N---SKGSLSARCDN-SGRCS-CKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDC 141
Query: 440 HGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGYVHDLEGNCIKKEVILPTPEGS 499
DP C ++G C+ C TG C+ C GY ++L+G PEG
Sbjct: 142 ----DPAGIAGPC--DAGRCV-CKPAVTGERCDRCRSGY-YNLDGG---------NPEGC 184
Query: 500 T 500
T
Sbjct: 185 T 185
Score = 79.7 bits (195), Expect = 8e-15
Identities = 45/144 (31%), Positives = 66/144 (45%), Gaps = 19/144 (13%)
Query: 311 CKVGVIGSICDRCQDGYYGF-SKNGCLPCQCNNR---SASCDALTGACLNCQENSKGNHC 366
C G C++C++G+Y ++ CLPC CN++ SA CD +G C +C+ G C
Sbjct: 56 CNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDN-SGRC-SCKPGVTGARC 113
Query: 367 EECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKSSELEPECDQ----CKDGYIGPNCNK 422
+ C GF+ DA C C + + CD CK G C++
Sbjct: 114 DRCLPGFHMLTDAG-----CTQDQRLLDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCDR 168
Query: 423 CENGYYNFD----SICRKCQCHGH 442
C +GYYN D C +C C+GH
Sbjct: 169 CRSGYYNLDGGNPEGCTQCFCYGH 192
Score = 58.2 bits (139), Expect = 2e-08
Identities = 29/86 (33%), Positives = 48/86 (55%), Gaps = 6/86 (6%)
Query: 241 CNCSVVGSLNVNRCNQTTGQC-ECRPGYQGLHCETCKEGFYLN----YTSGLCQPCDCSP 295
CN +V S + N C++ TG+C +C G++C+ CK G++ + + C+ C+C+P
Sbjct: 519 CNNNVDPSASGN-CDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNP 577
Query: 296 HGALSIPCNSSGKCQCKVGVIGSICD 321
G+ + C S G C CK G G C+
Sbjct: 578 MGSEPVGCRSDGTCVCKPGFGGPNCE 603
>gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens]
Length = 1193
Score = 120 bits (302), Expect = 3e-27
Identities = 64/186 (34%), Positives = 83/186 (44%), Gaps = 18/186 (9%)
Query: 308 KCQCKVGVIGSICDRCQDGYYGFSKN-----GCLPCQCNNRSASCDALTGACLNCQENSK 362
+C C VG G C C GY S C+PC C A CD TG C + EN
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA-CDPDTGDCYSGDENPD 439
Query: 363 GNHCEECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNK 422
C +C GFY P + C CPC + SCS+ E C+ C G G C
Sbjct: 440 -IECADCPIGFYNDPHDPRSCKPCPCH---NGFSCSVMPETEEVVCNNCPPGVTGARCEL 495
Query: 423 CENGYYNFD-------SICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCL 475
C +GY+ C+ CQC+ +VDP + C +G C+ C+HNT G +C+ C
Sbjct: 496 CADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGN-CDRLTGRCLKCIHNTAGIYCDQCK 554
Query: 476 EGYVHD 481
GY D
Sbjct: 555 AGYFGD 560
Score = 110 bits (276), Expect = 3e-24
Identities = 68/204 (33%), Positives = 95/204 (46%), Gaps = 41/204 (20%)
Query: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFYLN-YTSGLCQPCDCSPHGAL 299
CNC G+ C+ TG C + C C GFY + + C+PC C +
Sbjct: 416 CNCQGGGA-----CDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSC 470
Query: 300 SI-PCNSSGKCQ-CKVGVIGSICDRCQDGYYG--FSKNG----CLPCQCNNR-----SAS 346
S+ P C C GV G+ C+ C DGY+G F ++G C PCQCNN S +
Sbjct: 471 SVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGN 530
Query: 347 CDALTGACLNCQENSKGNHCEECKEGFY---QSPDATKECLRCPCSAV-------TSTGS 396
CD LTG CL C N+ G +C++CK G++ +P+ +C C C+ + S G+
Sbjct: 531 CDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGT 590
Query: 397 CSIKSSELEPECDQCKDGYIGPNC 420
C CK G+ GPNC
Sbjct: 591 C------------VCKPGFGGPNC 602
Score = 106 bits (264), Expect = 7e-23
Identities = 64/205 (31%), Positives = 92/205 (44%), Gaps = 33/205 (16%)
Query: 201 MPQKYLGKYACESNLKSKYLPLTQPVMNLRVSEAVKTEYVCNCS-----VVGSLNVNRCN 255
MP +LG C S L L + A VC+C+ + ++R
Sbjct: 1 MPALWLGCCLCFSLL-------------LPAARATSRREVCDCNGKSRQCIFDRELHRQT 47
Query: 256 QTTGQC-ECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALSIPCNSSGKCQCKVG 314
+C C G+HCE CK GFY + C PC+C+ G+LS C++SG+C CK G
Sbjct: 48 GNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRCSCKPG 107
Query: 315 VIGSICDRCQDGYYGFSKNGCL--------PCQCN--NRSASCDALTGACLNCQENSKGN 364
V G+ CDRC G++ + GC C C+ + CDA G C+ C+ G
Sbjct: 108 VTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDA--GRCV-CKPAVTGE 164
Query: 365 HCEECKEGFYQSPDATKE-CLRCPC 388
C+ C+ G+Y E C +C C
Sbjct: 165 RCDRCRSGYYNLDGGNPEGCTQCFC 189
Score = 95.1 bits (235), Expect = 2e-19
Identities = 49/117 (41%), Positives = 66/117 (56%), Gaps = 14/117 (11%)
Query: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGLCQP-------CDC 293
CNC+ GSL+ RC+ + G+C C+PG G C+ C GF++ +G Q CDC
Sbjct: 84 CNCNSKGSLSA-RCDNS-GRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDC 141
Query: 294 SPHGALSIPCNSSGKCQCKVGVIGSICDRCQDGYY---GFSKNGCLPCQCNNRSASC 347
P G ++ PC++ G+C CK V G CDRC+ GYY G + GC C C SASC
Sbjct: 142 DPAG-IAGPCDA-GRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSASC 196
Score = 80.5 bits (197), Expect = 4e-15
Identities = 60/181 (33%), Positives = 81/181 (44%), Gaps = 41/181 (22%)
Query: 338 CQCNNRSASC------DALTG---ACLNCQENSKGNHCEECKEGFYQSPDATKECLRCPC 388
C CN +S C TG CLNC +N+ G HCE+CK GFY+ + + CL C C
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDR-CLPCNC 86
Query: 389 SAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGYYNF-DSICR--------KCQC 439
+ S GS S + C CK G G C++C G++ D+ C KC C
Sbjct: 87 N---SKGSLSARCDN-SGRCS-CKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDC 141
Query: 440 HGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGYVHDLEGNCIKKEVILPTPEGS 499
DP C ++G C+ C TG C+ C GY ++L+G PEG
Sbjct: 142 ----DPAGIAGPC--DAGRCV-CKPAVTGERCDRCRSGY-YNLDGG---------NPEGC 184
Query: 500 T 500
T
Sbjct: 185 T 185
Score = 79.7 bits (195), Expect = 8e-15
Identities = 45/144 (31%), Positives = 66/144 (45%), Gaps = 19/144 (13%)
Query: 311 CKVGVIGSICDRCQDGYYGF-SKNGCLPCQCNNR---SASCDALTGACLNCQENSKGNHC 366
C G C++C++G+Y ++ CLPC CN++ SA CD +G C +C+ G C
Sbjct: 56 CNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDN-SGRC-SCKPGVTGARC 113
Query: 367 EECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKSSELEPECDQ----CKDGYIGPNCNK 422
+ C GF+ DA C C + + CD CK G C++
Sbjct: 114 DRCLPGFHMLTDAG-----CTQDQRLLDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCDR 168
Query: 423 CENGYYNFD----SICRKCQCHGH 442
C +GYYN D C +C C+GH
Sbjct: 169 CRSGYYNLDGGNPEGCTQCFCYGH 192
Score = 58.2 bits (139), Expect = 2e-08
Identities = 29/86 (33%), Positives = 48/86 (55%), Gaps = 6/86 (6%)
Query: 241 CNCSVVGSLNVNRCNQTTGQC-ECRPGYQGLHCETCKEGFYLN----YTSGLCQPCDCSP 295
CN +V S + N C++ TG+C +C G++C+ CK G++ + + C+ C+C+P
Sbjct: 519 CNNNVDPSASGN-CDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNP 577
Query: 296 HGALSIPCNSSGKCQCKVGVIGSICD 321
G+ + C S G C CK G G C+
Sbjct: 578 MGSEPVGCRSDGTCVCKPGFGGPNCE 603
>gi|62868217 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 114 bits (285), Expect = 3e-25
Identities = 72/211 (34%), Positives = 99/211 (46%), Gaps = 22/211 (10%)
Query: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFY-LNYTSGL-CQPCDCSPHGA 298
C C G++ C+ TGQC C+ QG C+ CK GF L Y + C CDC+ G+
Sbjct: 379 CECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGS 438
Query: 299 -LSIPCN-SSGKCQCKVGVIGSICDRCQDGYYGF-SKNGCLPCQC---NNRSASCDALTG 352
+PC+ SG+C C V+G CD+C ++ S GC PC C N+ S C+ TG
Sbjct: 439 RRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTG 498
Query: 353 ACLNCQENSKGNHCEECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKSSELEPECDQ-- 410
C C+E G C Q PD T + C A C + +E P CD+
Sbjct: 499 QC-PCREGFGGLMCSAA--AIRQCPDRTYGDVATGCRAC----DCDFRGTE-GPGCDKAS 550
Query: 411 ----CKDGYIGPNCNKCENGYYNFDSICRKC 437
C+ G GP C++C+ GY N +C C
Sbjct: 551 GRCLCRPGLTGPRCDQCQRGYCNRYPVCVAC 581
Score = 101 bits (252), Expect = 2e-21
Identities = 75/249 (30%), Positives = 107/249 (42%), Gaps = 47/249 (18%)
Query: 259 GQCE-CRPGYQGLHCETCKEGFYLNYTSG-----LCQPCDCSPHGAL-SIPCNS-SGKCQ 310
G C+ CR +G +CE C+ ++ N G C C+C P GA+ PC+ +G+C
Sbjct: 341 GVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCV 400
Query: 311 CKVGVIGSICDRCQDGYYGF---SKNGCLPCQCN----NRSASCDALTGACLNCQENSKG 363
CK V G CD C+ G+ G + GC C CN R CD +G CL C N G
Sbjct: 401 CKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCL-CLPNVVG 459
Query: 364 NHCEECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKSSELEPECDQ------CKDGYIG 417
C++C ++ + + C C C S L P+C+Q C++G+ G
Sbjct: 460 PKCDQCAP-YHWKLASGQGCEPCACDPHNS----------LSPQCNQFTGQCPCREGFGG 508
Query: 418 PNCNKC------ENGYYNFDSICRKCQC--HGHVDPVKTPKICKPESGECINCLHNTTGF 469
C+ + Y + + CR C C G P C SG C+ C TG
Sbjct: 509 LMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPG-----CDKASGRCL-CRPGLTGP 562
Query: 470 WCENCLEGY 478
C+ C GY
Sbjct: 563 RCDQCQRGY 571
Score = 101 bits (252), Expect = 2e-21
Identities = 53/189 (28%), Positives = 87/189 (46%), Gaps = 10/189 (5%)
Query: 207 GKYACESNLKSKYLPLTQPVMNLRVSEAVKTEYVCNCSVVGSLNVNRCNQTTGQCECRPG 266
G+ C+ +++ + L +P + + C+C+++GS C++ +G+C C P
Sbjct: 397 GQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPN 456
Query: 267 YQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALSIPCNS-SGKCQCKVGVIGSICD---- 321
G C+ C + + C+PC C PH +LS CN +G+C C+ G G +C
Sbjct: 457 VVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAI 516
Query: 322 -RCQDGYYGFSKNGCLPCQCNNRSAS---CDALTGACLNCQENSKGNHCEECKEGFYQSP 377
+C D YG GC C C+ R CD +G CL C+ G C++C+ G+
Sbjct: 517 RQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCL-CRPGLTGPRCDQCQRGYCNRY 575
Query: 378 DATKECLRC 386
C C
Sbjct: 576 PVCVACHPC 584
Score = 77.8 bits (190), Expect = 3e-14
Identities = 55/200 (27%), Positives = 80/200 (40%), Gaps = 47/200 (23%)
Query: 309 CQCKVGVIGSICDRCQDGYY--------GFSKNGCLPCQCNNRSASCD-----------A 349
C C+ G C+RC Y G + C C CN S +C A
Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 338
Query: 350 LTGACLNCQENSKGNHCEECKEGFYQS--PDAT--KECLRC-----------PCSAVTST 394
G C NC+++++G +CE C+ ++++ P A+ + C+ C PC V T
Sbjct: 339 YGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPV--T 396
Query: 395 GSCSIKSSELEPECDQCKDGYIGPNCNKCENGYYNFDSICRKCQCHGHVDPVKTPKICKP 454
G C K CD CK G+ G Y C +C C ++ + C
Sbjct: 397 GQCVCKEHVQGERCDLCKPGFTGLT--------YANPQGCHRCDC--NILGSRRDMPCDE 446
Query: 455 ESGECINCLHNTTGFWCENC 474
ESG C+ CL N G C+ C
Sbjct: 447 ESGRCL-CLPNVVGPKCDQC 465
Score = 31.2 bits (69), Expect = 3.1
Identities = 19/55 (34%), Positives = 21/55 (38%), Gaps = 20/55 (36%)
Query: 437 CQCHGHVDPVKTPKICKPESGE-------------CINCLHNTTGFWCENCLEGY 478
C CHGH D C P+ G C+ C HNT G CE C Y
Sbjct: 250 CFCHGHADR------CAPKPGASAGPSTAVQVHDVCV-CQHNTAGPNCERCAPFY 297
>gi|62868215 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 114 bits (285), Expect = 3e-25
Identities = 72/211 (34%), Positives = 99/211 (46%), Gaps = 22/211 (10%)
Query: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFY-LNYTSGL-CQPCDCSPHGA 298
C C G++ C+ TGQC C+ QG C+ CK GF L Y + C CDC+ G+
Sbjct: 379 CECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGS 438
Query: 299 -LSIPCN-SSGKCQCKVGVIGSICDRCQDGYYGF-SKNGCLPCQC---NNRSASCDALTG 352
+PC+ SG+C C V+G CD+C ++ S GC PC C N+ S C+ TG
Sbjct: 439 RRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTG 498
Query: 353 ACLNCQENSKGNHCEECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKSSELEPECDQ-- 410
C C+E G C Q PD T + C A C + +E P CD+
Sbjct: 499 QC-PCREGFGGLMCSAA--AIRQCPDRTYGDVATGCRAC----DCDFRGTE-GPGCDKAS 550
Query: 411 ----CKDGYIGPNCNKCENGYYNFDSICRKC 437
C+ G GP C++C+ GY N +C C
Sbjct: 551 GRCLCRPGLTGPRCDQCQRGYCNRYPVCVAC 581
Score = 101 bits (252), Expect = 2e-21
Identities = 75/249 (30%), Positives = 107/249 (42%), Gaps = 47/249 (18%)
Query: 259 GQCE-CRPGYQGLHCETCKEGFYLNYTSG-----LCQPCDCSPHGAL-SIPCNS-SGKCQ 310
G C+ CR +G +CE C+ ++ N G C C+C P GA+ PC+ +G+C
Sbjct: 341 GVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCV 400
Query: 311 CKVGVIGSICDRCQDGYYGF---SKNGCLPCQCN----NRSASCDALTGACLNCQENSKG 363
CK V G CD C+ G+ G + GC C CN R CD +G CL C N G
Sbjct: 401 CKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCL-CLPNVVG 459
Query: 364 NHCEECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKSSELEPECDQ------CKDGYIG 417
C++C ++ + + C C C S L P+C+Q C++G+ G
Sbjct: 460 PKCDQCAP-YHWKLASGQGCEPCACDPHNS----------LSPQCNQFTGQCPCREGFGG 508
Query: 418 PNCNKC------ENGYYNFDSICRKCQC--HGHVDPVKTPKICKPESGECINCLHNTTGF 469
C+ + Y + + CR C C G P C SG C+ C TG
Sbjct: 509 LMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPG-----CDKASGRCL-CRPGLTGP 562
Query: 470 WCENCLEGY 478
C+ C GY
Sbjct: 563 RCDQCQRGY 571
Score = 101 bits (252), Expect = 2e-21
Identities = 53/189 (28%), Positives = 87/189 (46%), Gaps = 10/189 (5%)
Query: 207 GKYACESNLKSKYLPLTQPVMNLRVSEAVKTEYVCNCSVVGSLNVNRCNQTTGQCECRPG 266
G+ C+ +++ + L +P + + C+C+++GS C++ +G+C C P
Sbjct: 397 GQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPN 456
Query: 267 YQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALSIPCNS-SGKCQCKVGVIGSICD---- 321
G C+ C + + C+PC C PH +LS CN +G+C C+ G G +C
Sbjct: 457 VVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAI 516
Query: 322 -RCQDGYYGFSKNGCLPCQCNNRSAS---CDALTGACLNCQENSKGNHCEECKEGFYQSP 377
+C D YG GC C C+ R CD +G CL C+ G C++C+ G+
Sbjct: 517 RQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCL-CRPGLTGPRCDQCQRGYCNRY 575
Query: 378 DATKECLRC 386
C C
Sbjct: 576 PVCVACHPC 584
Score = 77.8 bits (190), Expect = 3e-14
Identities = 55/200 (27%), Positives = 80/200 (40%), Gaps = 47/200 (23%)
Query: 309 CQCKVGVIGSICDRCQDGYY--------GFSKNGCLPCQCNNRSASCD-----------A 349
C C+ G C+RC Y G + C C CN S +C A
Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 338
Query: 350 LTGACLNCQENSKGNHCEECKEGFYQS--PDAT--KECLRC-----------PCSAVTST 394
G C NC+++++G +CE C+ ++++ P A+ + C+ C PC V T
Sbjct: 339 YGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPV--T 396
Query: 395 GSCSIKSSELEPECDQCKDGYIGPNCNKCENGYYNFDSICRKCQCHGHVDPVKTPKICKP 454
G C K CD CK G+ G Y C +C C ++ + C
Sbjct: 397 GQCVCKEHVQGERCDLCKPGFTGLT--------YANPQGCHRCDC--NILGSRRDMPCDE 446
Query: 455 ESGECINCLHNTTGFWCENC 474
ESG C+ CL N G C+ C
Sbjct: 447 ESGRCL-CLPNVVGPKCDQC 465
Score = 31.2 bits (69), Expect = 3.1
Identities = 19/55 (34%), Positives = 21/55 (38%), Gaps = 20/55 (36%)
Query: 437 CQCHGHVDPVKTPKICKPESGE-------------CINCLHNTTGFWCENCLEGY 478
C CHGH D C P+ G C+ C HNT G CE C Y
Sbjct: 250 CFCHGHADR------CAPKPGASAGPSTAVQVHDVCV-CQHNTAGPNCERCAPFY 297
>gi|189083719 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 114 bits (285), Expect = 3e-25
Identities = 72/211 (34%), Positives = 99/211 (46%), Gaps = 22/211 (10%)
Query: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFY-LNYTSGL-CQPCDCSPHGA 298
C C G++ C+ TGQC C+ QG C+ CK GF L Y + C CDC+ G+
Sbjct: 379 CECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGS 438
Query: 299 -LSIPCN-SSGKCQCKVGVIGSICDRCQDGYYGF-SKNGCLPCQC---NNRSASCDALTG 352
+PC+ SG+C C V+G CD+C ++ S GC PC C N+ S C+ TG
Sbjct: 439 RRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTG 498
Query: 353 ACLNCQENSKGNHCEECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKSSELEPECDQ-- 410
C C+E G C Q PD T + C A C + +E P CD+
Sbjct: 499 QC-PCREGFGGLMCSAA--AIRQCPDRTYGDVATGCRAC----DCDFRGTE-GPGCDKAS 550
Query: 411 ----CKDGYIGPNCNKCENGYYNFDSICRKC 437
C+ G GP C++C+ GY N +C C
Sbjct: 551 GRCLCRPGLTGPRCDQCQRGYCNRYPVCVAC 581
Score = 101 bits (252), Expect = 2e-21
Identities = 75/249 (30%), Positives = 107/249 (42%), Gaps = 47/249 (18%)
Query: 259 GQCE-CRPGYQGLHCETCKEGFYLNYTSG-----LCQPCDCSPHGAL-SIPCNS-SGKCQ 310
G C+ CR +G +CE C+ ++ N G C C+C P GA+ PC+ +G+C
Sbjct: 341 GVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCV 400
Query: 311 CKVGVIGSICDRCQDGYYGF---SKNGCLPCQCN----NRSASCDALTGACLNCQENSKG 363
CK V G CD C+ G+ G + GC C CN R CD +G CL C N G
Sbjct: 401 CKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCL-CLPNVVG 459
Query: 364 NHCEECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKSSELEPECDQ------CKDGYIG 417
C++C ++ + + C C C S L P+C+Q C++G+ G
Sbjct: 460 PKCDQCAP-YHWKLASGQGCEPCACDPHNS----------LSPQCNQFTGQCPCREGFGG 508
Query: 418 PNCNKC------ENGYYNFDSICRKCQC--HGHVDPVKTPKICKPESGECINCLHNTTGF 469
C+ + Y + + CR C C G P C SG C+ C TG
Sbjct: 509 LMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPG-----CDKASGRCL-CRPGLTGP 562
Query: 470 WCENCLEGY 478
C+ C GY
Sbjct: 563 RCDQCQRGY 571
Score = 101 bits (252), Expect = 2e-21
Identities = 53/189 (28%), Positives = 87/189 (46%), Gaps = 10/189 (5%)
Query: 207 GKYACESNLKSKYLPLTQPVMNLRVSEAVKTEYVCNCSVVGSLNVNRCNQTTGQCECRPG 266
G+ C+ +++ + L +P + + C+C+++GS C++ +G+C C P
Sbjct: 397 GQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPN 456
Query: 267 YQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALSIPCNS-SGKCQCKVGVIGSICD---- 321
G C+ C + + C+PC C PH +LS CN +G+C C+ G G +C
Sbjct: 457 VVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAI 516
Query: 322 -RCQDGYYGFSKNGCLPCQCNNRSAS---CDALTGACLNCQENSKGNHCEECKEGFYQSP 377
+C D YG GC C C+ R CD +G CL C+ G C++C+ G+
Sbjct: 517 RQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCL-CRPGLTGPRCDQCQRGYCNRY 575
Query: 378 DATKECLRC 386
C C
Sbjct: 576 PVCVACHPC 584
Score = 77.8 bits (190), Expect = 3e-14
Identities = 55/200 (27%), Positives = 80/200 (40%), Gaps = 47/200 (23%)
Query: 309 CQCKVGVIGSICDRCQDGYY--------GFSKNGCLPCQCNNRSASCD-----------A 349
C C+ G C+RC Y G + C C CN S +C A
Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 338
Query: 350 LTGACLNCQENSKGNHCEECKEGFYQS--PDAT--KECLRC-----------PCSAVTST 394
G C NC+++++G +CE C+ ++++ P A+ + C+ C PC V T
Sbjct: 339 YGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPV--T 396
Query: 395 GSCSIKSSELEPECDQCKDGYIGPNCNKCENGYYNFDSICRKCQCHGHVDPVKTPKICKP 454
G C K CD CK G+ G Y C +C C ++ + C
Sbjct: 397 GQCVCKEHVQGERCDLCKPGFTGLT--------YANPQGCHRCDC--NILGSRRDMPCDE 446
Query: 455 ESGECINCLHNTTGFWCENC 474
ESG C+ CL N G C+ C
Sbjct: 447 ESGRCL-CLPNVVGPKCDQC 465
Score = 31.2 bits (69), Expect = 3.1
Identities = 19/55 (34%), Positives = 21/55 (38%), Gaps = 20/55 (36%)
Query: 437 CQCHGHVDPVKTPKICKPESGE-------------CINCLHNTTGFWCENCLEGY 478
C CHGH D C P+ G C+ C HNT G CE C Y
Sbjct: 250 CFCHGHADR------CAPKPGASAGPSTAVQVHDVCV-CQHNTAGPNCERCAPFY 297
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 105 bits (263), Expect = 1e-22
Identities = 77/258 (29%), Positives = 110/258 (42%), Gaps = 33/258 (12%)
Query: 304 NSSGKCQCKVGVIGSICDRCQDGYYGFSKNG-----CLPCQCNNRSASCDALTGACLNCQ 358
+S +C+C +G G C+ C D ++ G C C CN ++SCD + G CLNCQ
Sbjct: 726 HSVEECRCPIGYSGLSCESC-DAHFTRVPGGPYLGTCSGCNCNGHASSCDPVYGHCLNCQ 784
Query: 359 ENSKGNHCEECKEGFYQSPDATK----ECLRCPCSAVTSTGSCS---IKSSELEPECDQC 411
N++G C +CK GF+ DA K C CPC + ++ S ++ + CD C
Sbjct: 785 HNTEGPQCNKCKAGFF--GDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDAC 842
Query: 412 KDGYIGPNCNKCENGYYNFDSICRKCQCHGHVDPVKTPKICKPE------SGECINCLHN 465
GY G C C GY Q G PV + E SGE C +N
Sbjct: 843 APGYTGRRCESCAPGYEG-----NPIQPGGKCRPVNQEIVRCDERGSMGTSGEACRCKNN 897
Query: 466 TTGFWCENCLEGYVHDLEGN---CIKKEVILPTPEGSTILVSNASLTTSVPTP----VIN 518
G C C +G H N C+K + + ++ S A L + P + N
Sbjct: 898 VVGRLCNECADGSFHLSTRNPDGCLKCFCMGVSRHCTSSSWSRAQLHGASEEPGHFSLTN 957
Query: 519 STFTPTTLQTIFSVSTSE 536
+ T TT + IFS + E
Sbjct: 958 AASTHTTNEGIFSPTPGE 975
Score = 101 bits (251), Expect = 2e-21
Identities = 55/190 (28%), Positives = 80/190 (42%), Gaps = 18/190 (9%)
Query: 308 KCQCKVGVIGSICDRCQDGYY----GFSKNGCLPCQCNNRSASCDALTGACLNCQENSKG 363
+C C G G C C GY G C C C+ S +C+ TGAC CQ +++G
Sbjct: 1125 QCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACEPETGACQGCQHHTEG 1184
Query: 364 NHCEECKEGFYQSPD--ATKECLRCPCSAVTSTGSCS---IKSSELEPECDQCKDGYIGP 418
CE+C+ G+Y ++C CPC + G + ++ P CD C G+ G
Sbjct: 1185 PRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHSGR 1244
Query: 419 NCNKCENGYYNFDSICRKCQCHGHV--------DPVKTPKICKPESGECINCLHNTTGFW 470
+C +C GYY S + CQ V DP + +G+C C G
Sbjct: 1245 HCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDAAGQC-QCKAQVEGLT 1303
Query: 471 CENCLEGYVH 480
C +C + H
Sbjct: 1304 CSHCRPHHFH 1313
Score = 92.4 bits (228), Expect = 1e-18
Identities = 64/210 (30%), Positives = 85/210 (40%), Gaps = 33/210 (15%)
Query: 260 QCECRPGYQGLHCETCKEGFYLNYTSGL----CQPCDCSPHGALSIPCNSSGKCQ-CKVG 314
QC C PGY+G C+ C G Y SGL C+ C C H P +G CQ C+
Sbjct: 1125 QCSCPPGYRGPSCQDCDTG-YTRTPSGLYLGTCERCSCHGHSEACEP--ETGACQGCQHH 1181
Query: 315 VIGSICDRCQDGYYGFSKNG----CLPCQCNNRSASCDAL---------TGACLNCQENS 361
G C++CQ GYYG ++ G C C C A+ A C C
Sbjct: 1182 TEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGH 1241
Query: 362 KGNHCEECKEGFYQSPDATKECLRCPCSAVTSTGSCSI-KSSELEPECD-----QCKDGY 415
G HCE C G+Y +P + C R S V C+ + +CD QCK
Sbjct: 1242 SGRHCERCAPGYYGNPSQGQPCQR--DSQVPGPIGCNCDPQGSVSSQCDAAGQCQCKAQV 1299
Query: 416 IGPNCNKCENGYYNFDSI----CRKCQCHG 441
G C+ C +++ + C C C G
Sbjct: 1300 EGLTCSHCRPHHFHLSASNPDGCLPCFCMG 1329
Score = 84.3 bits (207), Expect = 3e-16
Identities = 48/136 (35%), Positives = 65/136 (47%), Gaps = 21/136 (15%)
Query: 260 QCECRPGYQGLHCETCKEGFYLNYTSGL----CQPCDCSPHGALSIPCNSSGKC-QCKVG 314
+C C PGY GL C+ C G Y SGL C+ C+C+ H L P +G C QC+
Sbjct: 1529 ECRCPPGYIGLSCQDCAPG-YTRTGSGLYLGHCELCECNGHSDLCHP--ETGACSQCQHN 1585
Query: 315 VIGSICDRCQDGYYGFSKNG----CLPCQC------NNRSASCDALTGA---CLNCQENS 361
G C+ C GYYG + G C PC C N S +C++L C C+
Sbjct: 1586 AAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGY 1645
Query: 362 KGNHCEECKEGFYQSP 377
G +CE+C G+ +P
Sbjct: 1646 TGQYCEQCGPGYVGNP 1661
Score = 82.8 bits (203), Expect = 9e-16
Identities = 45/135 (33%), Positives = 55/135 (40%), Gaps = 9/135 (6%)
Query: 308 KCQCKVGVIGSICDRCQDGYY----GFSKNGCLPCQCNNRSASCDALTGACLNCQENSKG 363
+C+C G IG C C GY G C C+CN S C TGAC CQ N+ G
Sbjct: 1529 ECRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDLCHPETGACSQCQHNAAG 1588
Query: 364 NHCEECKEGFYQSPDA--TKECLRCPCSAVTSTGSCSIKSSELEP---ECDQCKDGYIGP 418
CE C G+Y A ++C C C S L C C+ GY G
Sbjct: 1589 EFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGYTGQ 1648
Query: 419 NCNKCENGYYNFDSI 433
C +C GY S+
Sbjct: 1649 YCEQCGPGYVGNPSV 1663
Score = 82.4 bits (202), Expect = 1e-15
Identities = 67/260 (25%), Positives = 102/260 (39%), Gaps = 50/260 (19%)
Query: 215 LKSKYLPLTQPVMNLRVSEAVKTEYVCNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCET 274
L+S L Q V N +++ ++ + +V + + R + +C C GY GL CE+
Sbjct: 686 LQSLEAVLIQTVYNTKMASVGLSDIAMDTTVTHATSHGRAHSVE-ECRCPIGYSGLSCES 744
Query: 275 CKEGF-------YLNYTSGLCQPCDCSPHGALSIPCNSSGKC-QCKVGVIGSICDRCQDG 326
C F YL G C C+C+ H + P G C C+ G C++C+ G
Sbjct: 745 CDAHFTRVPGGPYL----GTCSGCNCNGHASSCDPV--YGHCLNCQHNTEGPQCNKCKAG 798
Query: 327 YYG----FSKNGCLPCQCNNRSAS------CDALT---GACLNCQENSKGNHCEECKEGF 373
++G + C PC C AS C T C C G CE C G+
Sbjct: 799 FFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGYTGRRCESCAPGY 858
Query: 374 YQSP--------DATKECLRCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCEN 425
+P +E +RC T E +CK+ +G CN+C +
Sbjct: 859 EGNPIQPGGKCRPVNQEIVRCDERGSMGTSG----------EACRCKNNVVGRLCNECAD 908
Query: 426 GYYNFDSI----CRKCQCHG 441
G ++ + C KC C G
Sbjct: 909 GSFHLSTRNPDGCLKCFCMG 928
Score = 79.0 bits (193), Expect = 1e-14
Identities = 37/98 (37%), Positives = 52/98 (53%), Gaps = 13/98 (13%)
Query: 263 CRPGYQGLHCETCKEGFYLNYTSGL-CQP---------CDCSPHGALSIPCNSSGKCQCK 312
C PG+ G HCE C G+Y N + G CQ C+C P G++S C+++G+CQCK
Sbjct: 1237 CSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDAAGQCQCK 1296
Query: 313 VGVIGSICDRCQDGYYGFS---KNGCLPCQCNNRSASC 347
V G C C+ ++ S +GCLPC C + C
Sbjct: 1297 AQVEGLTCSHCRPHHFHLSASNPDGCLPCFCMGITQQC 1334
Score = 71.6 bits (174), Expect = 2e-12
Identities = 34/85 (40%), Positives = 42/85 (49%), Gaps = 11/85 (12%)
Query: 404 LEPECDQCKDGYIGPNCNKCENGYYNFDS-----ICRKCQCHGHVDPVKTPKICKPESGE 458
LE E C GY GP+C C+ GY S C +C CHGH + C+PE+G
Sbjct: 1121 LEVEQCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEA------CEPETGA 1174
Query: 459 CINCLHNTTGFWCENCLEGYVHDLE 483
C C H+T G CE C GY D +
Sbjct: 1175 CQGCQHHTEGPRCEQCQPGYYGDAQ 1199
Score = 68.6 bits (166), Expect = 2e-11
Identities = 49/144 (34%), Positives = 61/144 (42%), Gaps = 38/144 (26%)
Query: 370 KEGFYQSPD---ATKECL------------RCPCSAVTSTGSCSIKSSE----------- 403
+E F++ PD AT+E L R S+V S S S E
Sbjct: 1464 REEFWRRPDGQPATREHLLMALADLDELLIRATFSSVPLAASISAVSLEVAQPGPSNRPR 1523
Query: 404 -LEPECDQCKDGYIGPNCNKCENGYYNFDS-----ICRKCQCHGHVDPVKTPKICKPESG 457
LE E +C GYIG +C C GY S C C+C+GH D +C PE+G
Sbjct: 1524 ALEVEECRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSD------LCHPETG 1577
Query: 458 ECINCLHNTTGFWCENCLEGYVHD 481
C C HN G +CE C GY D
Sbjct: 1578 ACSQCQHNAAGEFCELCAPGYYGD 1601
Score = 59.3 bits (142), Expect = 1e-08
Identities = 51/190 (26%), Positives = 77/190 (40%), Gaps = 28/190 (14%)
Query: 163 RTPTPDLPSSSNSSVLPTPPATEAPSSPPPGHQWPVAKMPQKYLGKYACESNLKSKYLPL 222
R +P +++ S + A PS+ P + + P Y+G +C+
Sbjct: 1494 RATFSSVPLAASISAVSLEVAQPGPSNRPRALEVEECRCPPGYIG-LSCQDCAPG----Y 1548
Query: 223 TQPVMNLRVSEAVKTEYVCNCSVVGSLNVNRCNQTTGQC-ECRPGYQGLHCETCKEGFYL 281
T+ L + +C C+ L C+ TG C +C+ G CE C G+Y
Sbjct: 1549 TRTGSGLYLGHCE----LCECNGHSDL----CHPETGACSQCQHNAAGEFCELCAPGYYG 1600
Query: 282 NYTSGL---CQPCDC---SPHGALSIPCNSSG----KC-QCKVGVIGSICDRCQDGYYG- 329
+ T+G CQPC C +P S C S G +C C+ G G C++C GY G
Sbjct: 1601 DATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGYTGQYCEQCGPGYVGN 1660
Query: 330 --FSKNGCLP 337
CLP
Sbjct: 1661 PSVQGGQCLP 1670
Score = 43.9 bits (102), Expect = 5e-04
Identities = 36/141 (25%), Positives = 49/141 (34%), Gaps = 32/141 (22%)
Query: 357 CQENSKGNHCEECKEGFYQSPDATK--ECLRCPCSAVTSTGSCSIKSSELEPE---CDQC 411
C G C++C G+ ++ C C C+ S PE C QC
Sbjct: 1532 CPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNG---------HSDLCHPETGACSQC 1582
Query: 412 KDGYIGPNCNKCENGYYNFDSI-----CRKCQCHGHVDPVKTP-----KICKPESG---E 458
+ G C C GYY + C+ C C P+ P + C+
Sbjct: 1583 QHNAAGEFCELCAPGYYGDATAGTPEDCQPCAC-----PLTNPENMFSRTCESLGAGGYR 1637
Query: 459 CINCLHNTTGFWCENCLEGYV 479
C C TG +CE C GYV
Sbjct: 1638 CTACEPGYTGQYCEQCGPGYV 1658
Score = 38.5 bits (88), Expect = 0.019
Identities = 20/55 (36%), Positives = 33/55 (60%), Gaps = 4/55 (7%)
Query: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCK-EGFYLNYTS-GLCQPCDC 293
CNC GS++ ++C+ GQC+C+ +GL C C+ F+L+ ++ C PC C
Sbjct: 1275 CNCDPQGSVS-SQCD-AAGQCQCKAQVEGLTCSHCRPHHFHLSASNPDGCLPCFC 1327
>gi|14192943 multiple EGF-like-domains 10 [Homo sapiens]
Length = 1140
Score = 102 bits (254), Expect = 1e-21
Identities = 92/308 (29%), Positives = 122/308 (39%), Gaps = 82/308 (26%)
Query: 235 VKTEYVCNCSVVGSLNVNRCNQTTGQCECRPGYQGLHC-ETCKEGFYLNYTSGLCQ---- 289
+K + C C + N + C+ +G+C C+PG+ GL+C ETC GFY +C
Sbjct: 362 IKCDKRCPCHLE---NTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNG 418
Query: 290 --------PCDCSPH------------GALSIPCNS-------------SGKCQCKVGVI 316
C C+P G I C+S G C CK G
Sbjct: 419 ADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWH 478
Query: 317 GSICD-RCQDGYYGFSKNGCLPCQCNNRSASCDALTGACLNCQENSKGNHCE-ECKEGFY 374
G C RC G +GF N L CQC N A C+ L G C C +G CE C++G Y
Sbjct: 479 GVDCSIRCPSGTWGFGCN--LTCQCLNGGA-CNTLDGTC-TCAPGWRGEKCELPCQDGTY 534
Query: 375 QSPDATKECLRCPCSAV----TSTGSCSIKSSELEPECDQ-CKDGYIGPNCN---KCENG 426
A RC CS +TG C CD C +G GPNC+ C+NG
Sbjct: 535 GLNCAE----RCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNG 590
Query: 427 YYNFDSICRK----CQCHGHVDPVKTPKICKPE------SGECINCLHNT------TGFW 470
+ C C+C +IC P S C C+H++ TG
Sbjct: 591 -----ASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGL- 644
Query: 471 CENCLEGY 478
C+ CL G+
Sbjct: 645 CD-CLPGF 651
Score = 100 bits (248), Expect = 5e-21
Identities = 77/244 (31%), Positives = 110/244 (45%), Gaps = 41/244 (16%)
Query: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCET-CKEGFYLNYTSGLCQPCDCSPHGAL 299
C+CS + + C+ TTG C C PG+ G+HC++ C EG + PC C +GA
Sbjct: 542 CDCS-----HADGCHPTTGHCRCLPGWSGVHCDSVCAEG---RWGPNCSLPCYCK-NGAS 592
Query: 300 SIPCNSSGKCQCKVGVIGSICDR-CQDGYYGFSKNGCLPCQCNNRSASCDALTGACLNCQ 358
P G C+C G G+ C R C G+YG + P QC + S C +TG C +C
Sbjct: 593 CSP--DDGICECAPGFRGTTCQRICSPGFYGHRCSQTCP-QCVHSSGPCHHITGLC-DCL 648
Query: 359 ENSKGNHCEE-CKEGFYQSPDATKECLR-CPCSAVTSTGSCSIKSSELEPECDQCKDGYI 416
G C E C G + K C C C T+ G+C + ++ C QC G+I
Sbjct: 649 PGFTGALCNEVCPSGRF-----GKNCAGICTC---TNNGTC----NPIDRSC-QCYPGWI 695
Query: 417 GPNCNK-CENGYYNFDSICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWC-ENC 474
G +C++ C ++ + I C CH C GEC C TG +C + C
Sbjct: 696 GSDCSQPCPPAHWGPNCI-HTCNCHNGA-------FCSAYDGEC-KCTPGWTGLYCTQRC 746
Query: 475 LEGY 478
G+
Sbjct: 747 PLGF 750
Score = 98.6 bits (244), Expect = 2e-20
Identities = 76/250 (30%), Positives = 101/250 (40%), Gaps = 52/250 (20%)
Query: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALS 300
C C N C+ TG+C C PGY G CE LC P P
Sbjct: 195 CQCQ-----NGATCDHVTGECRCPPGYTGAFCE------------DLCPPGKHGPQCEQR 237
Query: 301 IPCNS-------SGKCQCKVGVIGSICDR-CQDGYYGFSKNGCLPCQCNNRSASCDALTG 352
PC + +G+C C G +G++C + C +G +G KN CQC+N +CDA TG
Sbjct: 238 CPCQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFG--KNCSQECQCHN-GGTCDAATG 294
Query: 353 ACLNCQENSKGNHC-EECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKSSELEPECDQC 411
C +C G C +EC G Y A C C + G C S C
Sbjct: 295 QC-HCSPGYTGERCQDECPVGTYGVLCAE----TCQC---VNGGKCYHVSGAC-----LC 341
Query: 412 KDGYIGPNCNK--CENGYYNFDSICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGF 469
+ G+ G C C G Y ++C CH ++ C P SGEC C +G
Sbjct: 342 EAGFAGERCEARLCPEGLYGI-KCDKRCPCH-----LENTHSCHPMSGECA-CKPGWSGL 394
Query: 470 WC-ENCLEGY 478
+C E C G+
Sbjct: 395 YCNETCSPGF 404
Score = 94.0 bits (232), Expect = 4e-19
Identities = 82/272 (30%), Positives = 107/272 (39%), Gaps = 64/272 (23%)
Query: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHC-ETCKEGFYLNYTSGLC-QPCDCSPHGA 298
C C N C+ TGQC C PGY G C + C G Y LC + C C G
Sbjct: 281 CQCH-----NGGTCDAATGQCHCSPGYTGERCQDECPVGTY----GVLCAETCQCVNGGK 331
Query: 299 LSIPCNSSGKCQCKVGVIGSICDR--CQDGYYGFSKNGCLPCQCNNRSASCDALTGACLN 356
+ SG C C+ G G C+ C +G YG + PC N + SC ++G C
Sbjct: 332 C---YHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLEN-THSCHPMSGECA- 386
Query: 357 CQENSKGNHCEE-CKEGFYQSPDATKECLRC----PCSAVTSTGSCSIKSSELEPECDQC 411
C+ G +C E C GFY +A ++ C C +V TG C+ C
Sbjct: 387 CKPGWSGLYCNETCSPGFY--GEACQQICSCQNGADCDSV--TGKCT------------C 430
Query: 412 KDGYIGPNCN-KCENGYYNFDSICRKCQCHGHVDPVKTPKICKPESGEC----------- 459
G+ G +C+ C G Y + R C C K +C P G C
Sbjct: 431 APGFKGIDCSTPCPLGTYGINCSSR-CGC-------KNDAVCSPVDGSCTCKAGWHGVDC 482
Query: 460 -INCLHNTTGFWCE---NCLE-GYVHDLEGNC 486
I C T GF C CL G + L+G C
Sbjct: 483 SIRCPSGTWGFGCNLTCQCLNGGACNTLDGTC 514
Score = 91.7 bits (226), Expect = 2e-18
Identities = 75/233 (32%), Positives = 101/233 (43%), Gaps = 35/233 (15%)
Query: 261 CECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALSIPCNSSGKCQCKVGVIGSIC 320
C+C PG+ G +C + +G + + C C +GAL P +G C C G G C
Sbjct: 124 CQCEPGWGGTNCSSACDGDH--WGPHCTSRCQCK-NGALCNPI--TGACHCAAGFRGWRC 178
Query: 321 -DRCQDGYYGFSKNGC-LPCQCNNRSASCDALTGACLNCQENSKGNHCEECKEGFYQSPD 378
DRC+ G YG N C CQC N A+CD +TG C C G CE+ P
Sbjct: 179 EDRCEQGTYG---NDCHQRCQCQN-GATCDHVTGEC-RCPPGYTGAFCEDLCPPGKHGPQ 233
Query: 379 ATKECLRCPCS----AVTSTGSCSIKSSELEPECDQ-CKDGYIGPNCN---KCENGYYNF 430
+ RCPC TG CS S + C Q C +G G NC+ +C NG
Sbjct: 234 CEQ---RCPCQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNG-GTC 289
Query: 431 DSICRKCQCH-GHVD-------PVKTPKICKPESGECIN---CLHNTTGFWCE 472
D+ +C C G+ PV T + E+ +C+N C H + CE
Sbjct: 290 DAATGQCHCSPGYTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSGACLCE 342
Score = 51.2 bits (121), Expect = 3e-06
Identities = 29/84 (34%), Positives = 38/84 (45%), Gaps = 12/84 (14%)
Query: 240 VCNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCE-TCKEGFYLNYTSGLCQPCDCSPHGA 298
+C C N C+ +GQC CR G+ G HCE C G Y G Q CDC +
Sbjct: 758 ICQCQ-----NGADCDHISGQCTCRTGFMGRHCEQKCPSG---TYGYGCRQICDCLNNST 809
Query: 299 LSIPCNSSGKCQCKVGVIGSICDR 322
+ +G C C G G+ CD+
Sbjct: 810 CD---HITGTCYCSPGWKGARCDQ 830
Score = 43.5 bits (101), Expect = 6e-04
Identities = 34/126 (26%), Positives = 51/126 (40%), Gaps = 30/126 (23%)
Query: 368 ECKEGFYQS-----PDATKECLRCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNK 422
+C GFY+S P +C+ C A P QC+ G+ G NC+
Sbjct: 93 QCCPGFYESGEMCVPHCADKCVHGRCIA---------------PNTCQCEPGWGGTNCSS 137
Query: 423 CENGYYNFDSICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCEN-CLEG-YVH 480
+G + +CQC K +C P +G C +C G+ CE+ C +G Y +
Sbjct: 138 ACDGDHWGPHCTSRCQC-------KNGALCNPITGAC-HCAAGFRGWRCEDRCEQGTYGN 189
Query: 481 DLEGNC 486
D C
Sbjct: 190 DCHQRC 195
>gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens]
Length = 1668
Score = 102 bits (254), Expect = 1e-21
Identities = 52/148 (35%), Positives = 70/148 (47%), Gaps = 17/148 (11%)
Query: 323 CQDGYY----GFSKNGCLPCQCNNRSASCDALTGACLNCQENSKGNHCEECKEGFYQSPD 378
C GYY G C+PC CN S C +G C+NCQ N+ G HCE C+EG+Y +
Sbjct: 59 CSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNA- 117
Query: 379 ATKECLRCPCSAVTSTGS-CSIKSSELEPECDQCKDGYIGPNCNKCENGYY----NFDSI 433
C CPC S + C + ++ C CK GY G C +C GY+ F
Sbjct: 118 VHGSCRACPCPHTNSFATGCVVNGGDV--RC-SCKAGYTGTQCERCAPGYFGNPQKFGGS 174
Query: 434 CRKCQCHGHVDPVKTPKICKPESGECIN 461
C+ C C+ + C P +G+CIN
Sbjct: 175 CQPCSCNSNGQLGS----CHPLTGDCIN 198
Score = 98.2 bits (243), Expect = 2e-20
Identities = 49/140 (35%), Positives = 72/140 (51%), Gaps = 15/140 (10%)
Query: 241 CNCSVVGSLNVNRCNQTTGQC-ECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGAL 299
CNC+ + N+C +G C C+ G HCE C+EG+Y N G C+ C C +
Sbjct: 78 CNCNG----HSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRACPCPHTNSF 133
Query: 300 SIPCNSSG---KCQCKVGVIGSICDRCQDGYYGFSK---NGCLPCQCNNRS--ASCDALT 351
+ C +G +C CK G G+ C+RC GY+G + C PC CN+ SC LT
Sbjct: 134 ATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLT 193
Query: 352 GACLNCQ--ENSKGNHCEEC 369
G C+N + ++S C++C
Sbjct: 194 GDCINQEPKDSSPAEECDDC 213
Score = 78.2 bits (191), Expect = 2e-14
Identities = 54/178 (30%), Positives = 78/178 (43%), Gaps = 25/178 (14%)
Query: 256 QTTGQCECRPGYQGLH-CETCKEGFYLNYT---SGLCQPCDCSPHGALSIPC-NSSGKC- 309
Q GQ + + Y + C G+Y ++ +G C PC+C+ H S C + SG C
Sbjct: 39 QPPGQSQLQASYVEFRPSQGCSPGYYRDHKGLYTGRCVPCNCNGH---SNQCQDGSGICV 95
Query: 310 QCKVGVIGSICDRCQDGYYGFSKNG-CLPCQC---NNRSASCDALTG-ACLNCQENSKGN 364
C+ G C+RCQ+GYYG + +G C C C N+ + C G +C+ G
Sbjct: 96 NCQHNTAGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGT 155
Query: 365 HCEECKEGFYQSPDA-TKECLRCPCSAVTSTGSC----------SIKSSELEPECDQC 411
CE C G++ +P C C C++ GSC K S ECD C
Sbjct: 156 QCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 213
Score = 54.7 bits (130), Expect = 3e-07
Identities = 27/70 (38%), Positives = 35/70 (50%), Gaps = 12/70 (17%)
Query: 423 CENGYYN-----FDSICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEG 477
C GYY + C C C+GH + C+ SG C+NC HNT G CE C EG
Sbjct: 59 CSPGYYRDHKGLYTGRCVPCNCNGHSNQ------CQDGSGICVNCQHNTAGEHCERCQEG 112
Query: 478 YV-HDLEGNC 486
Y + + G+C
Sbjct: 113 YYGNAVHGSC 122
Score = 49.3 bits (116), Expect = 1e-05
Identities = 32/114 (28%), Positives = 44/114 (38%), Gaps = 12/114 (10%)
Query: 369 CKEGFYQSPDA--TKECLRCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENG 426
C G+Y+ T C+ C C+ + C S C C+ G +C +C+ G
Sbjct: 59 CSPGYYRDHKGLYTGRCVPCNCNG--HSNQCQDGSGI----CVNCQHNTAGEHCERCQEG 112
Query: 427 YYN--FDSICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGY 478
YY CR C C H + T + C +C TG CE C GY
Sbjct: 113 YYGNAVHGSCRACPCP-HTNSFATGCVVNGGDVRC-SCKAGYTGTQCERCAPGY 164
>gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens]
Length = 1724
Score = 102 bits (254), Expect = 1e-21
Identities = 52/148 (35%), Positives = 70/148 (47%), Gaps = 17/148 (11%)
Query: 323 CQDGYY----GFSKNGCLPCQCNNRSASCDALTGACLNCQENSKGNHCEECKEGFYQSPD 378
C GYY G C+PC CN S C +G C+NCQ N+ G HCE C+EG+Y +
Sbjct: 59 CSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNA- 117
Query: 379 ATKECLRCPCSAVTSTGS-CSIKSSELEPECDQCKDGYIGPNCNKCENGYY----NFDSI 433
C CPC S + C + ++ C CK GY G C +C GY+ F
Sbjct: 118 VHGSCRACPCPHTNSFATGCVVNGGDV--RC-SCKAGYTGTQCERCAPGYFGNPQKFGGS 174
Query: 434 CRKCQCHGHVDPVKTPKICKPESGECIN 461
C+ C C+ + C P +G+CIN
Sbjct: 175 CQPCSCNSNGQLGS----CHPLTGDCIN 198
Score = 98.2 bits (243), Expect = 2e-20
Identities = 49/140 (35%), Positives = 72/140 (51%), Gaps = 15/140 (10%)
Query: 241 CNCSVVGSLNVNRCNQTTGQC-ECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGAL 299
CNC+ + N+C +G C C+ G HCE C+EG+Y N G C+ C C +
Sbjct: 78 CNCNG----HSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRACPCPHTNSF 133
Query: 300 SIPCNSSG---KCQCKVGVIGSICDRCQDGYYGFSK---NGCLPCQCNNRS--ASCDALT 351
+ C +G +C CK G G+ C+RC GY+G + C PC CN+ SC LT
Sbjct: 134 ATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLT 193
Query: 352 GACLNCQ--ENSKGNHCEEC 369
G C+N + ++S C++C
Sbjct: 194 GDCINQEPKDSSPAEECDDC 213
Score = 78.2 bits (191), Expect = 2e-14
Identities = 54/178 (30%), Positives = 78/178 (43%), Gaps = 25/178 (14%)
Query: 256 QTTGQCECRPGYQGLH-CETCKEGFYLNYT---SGLCQPCDCSPHGALSIPC-NSSGKC- 309
Q GQ + + Y + C G+Y ++ +G C PC+C+ H S C + SG C
Sbjct: 39 QPPGQSQLQASYVEFRPSQGCSPGYYRDHKGLYTGRCVPCNCNGH---SNQCQDGSGICV 95
Query: 310 QCKVGVIGSICDRCQDGYYGFSKNG-CLPCQC---NNRSASCDALTG-ACLNCQENSKGN 364
C+ G C+RCQ+GYYG + +G C C C N+ + C G +C+ G
Sbjct: 96 NCQHNTAGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGT 155
Query: 365 HCEECKEGFYQSPDA-TKECLRCPCSAVTSTGSC----------SIKSSELEPECDQC 411
CE C G++ +P C C C++ GSC K S ECD C
Sbjct: 156 QCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 213
Score = 54.7 bits (130), Expect = 3e-07
Identities = 27/70 (38%), Positives = 35/70 (50%), Gaps = 12/70 (17%)
Query: 423 CENGYYN-----FDSICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEG 477
C GYY + C C C+GH + C+ SG C+NC HNT G CE C EG
Sbjct: 59 CSPGYYRDHKGLYTGRCVPCNCNGHSNQ------CQDGSGICVNCQHNTAGEHCERCQEG 112
Query: 478 YV-HDLEGNC 486
Y + + G+C
Sbjct: 113 YYGNAVHGSC 122
Score = 49.3 bits (116), Expect = 1e-05
Identities = 32/114 (28%), Positives = 44/114 (38%), Gaps = 12/114 (10%)
Query: 369 CKEGFYQSPDA--TKECLRCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENG 426
C G+Y+ T C+ C C+ + C S C C+ G +C +C+ G
Sbjct: 59 CSPGYYRDHKGLYTGRCVPCNCNG--HSNQCQDGSGI----CVNCQHNTAGEHCERCQEG 112
Query: 427 YYN--FDSICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGY 478
YY CR C C H + T + C +C TG CE C GY
Sbjct: 113 YYGNAVHGSCRACPCP-HTNSFATGCVVNGGDVRC-SCKAGYTGTQCERCAPGY 164
>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
Length = 1044
Score = 101 bits (251), Expect = 2e-21
Identities = 83/275 (30%), Positives = 114/275 (41%), Gaps = 70/275 (25%)
Query: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCE--TCKEGFYLNYTSGLCQPCDCSPHGA 298
C+C N +C+ TTG CEC PGY+G C+ C EG + G PC C
Sbjct: 318 CDCH-----NGGQCSPTTGACECEPGYKGPRCQERLCPEGL---HGPGCTLPCPCDADNT 369
Query: 299 LSIPCNS-SGKCQCKVGVIGSIC-DRCQDGYYGFSKNGC-LPCQCNNRSASCDALTGAC- 354
+S C+ +G C C+ G G C + C GYYG +GC LPC C N A C ++TG C
Sbjct: 370 IS--CHPVTGACTCQPGWSGHHCNESCPVGYYG---DGCQLPCTCQN-GADCHSITGGCT 423
Query: 355 -----------LNCQENSKGNHCEE------------------CKEGFYQSPDATKEC-- 383
++C + G +C CKEG +Q D T C
Sbjct: 424 CAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEG-WQGLDCTLPCPS 482
Query: 384 ----LRCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNCN-KCENGYYNFDSICRKCQ 438
L C S + G+ S ++ C C G++G C C +G + + C
Sbjct: 483 GTWGLNCNESCTCANGAA---CSPIDGSC-SCTPGWLGDTCELPCPDGTFGL-NCSEHCD 537
Query: 439 CHGHVDPVKTPKICKPESGECINCLHNTTGFWCEN 473
C H D C P +G C CL TG C++
Sbjct: 538 C-SHADG------CDPVTGHCC-CLAGWTGIRCDS 564
Score = 97.1 bits (240), Expect = 5e-20
Identities = 86/272 (31%), Positives = 117/272 (43%), Gaps = 51/272 (18%)
Query: 253 RCNQTTGQCECRPGYQGLHC-ETCKEGFYLNYTSGLCQPCDCSPHGALSIPCNSSGKCQC 311
+C+ TGQC C GY G C E C G ++ Q CDC G S ++G C+C
Sbjct: 282 QCDHVTGQCHCTAGYMGDRCQEECPFG---SFGFQCSQHCDCHNGGQCS---PTTGACEC 335
Query: 312 KVGVIGSICDR--CQDGYYGFSKNGC-LPCQCN-NRSASCDALTGACLNCQENSKGNHC- 366
+ G G C C +G +G GC LPC C+ + + SC +TGAC CQ G+HC
Sbjct: 336 EPGYKGPRCQERLCPEGLHG---PGCTLPCPCDADNTISCHPVTGAC-TCQPGWSGHHCN 391
Query: 367 EECKEGFYQSPDATKECLRCPC----SAVTSTGSCSIKSSELEPECD-QCKDGYIGPNCN 421
E C G+Y D + L C C + TG C+ + C C G GPNC+
Sbjct: 392 ESCPVGYY--GDGCQ--LPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCS 447
Query: 422 KCENGYYNFDSICRKCQCHGHVDPVKTPKICKPESGECINC-LHNTTGFWCENCLEGYV- 479
SIC C G PV CK E + ++C L +G W NC E
Sbjct: 448 ----------SIC-SCNNGGTCSPVDGSCTCK-EGWQGLDCTLPCPSGTWGLNCNESCTC 495
Query: 480 ------HDLEGNC------IKKEVILPTPEGS 499
++G+C + LP P+G+
Sbjct: 496 ANGAACSPIDGSCSCTPGWLGDTCELPCPDGT 527
Score = 94.4 bits (233), Expect = 3e-19
Identities = 90/319 (28%), Positives = 125/319 (39%), Gaps = 84/319 (26%)
Query: 254 CNQTTGQCECRPGYQGLHCE----------------TCKEGFYLNYTSGLC--------- 288
C+ G+C C PGY G++CE C+ G ++ +G C
Sbjct: 197 CDPRAGECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGA 256
Query: 289 ---QPCDCSPHG---ALSIPCNS-------SGKCQCKVGVIGSIC-DRCQDGYYGFSKNG 334
QPC G + PC+ +G+C C G +G C + C G +GF +
Sbjct: 257 VCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCS- 315
Query: 335 CLPCQCNNRSASCDALTGACLNCQENSKGNHCEE--CKEGFYQSPDATKECLRCPCSAVT 392
C C+N C TGAC C+ KG C+E C EG + P T L CPC A
Sbjct: 316 -QHCDCHN-GGQCSPTTGAC-ECEPGYKGPRCQERLCPEGLH-GPGCT---LPCPCDADN 368
Query: 393 S------TGSCSIKSSELEPECDQCKDGYIGPNCNK-CENGYYNFDSICRKCQCHGHVD- 444
+ TG+C+ C+ G+ G +CN+ C GYY D C C D
Sbjct: 369 TISCHPVTGACT------------CQPGWSGHHCNESCPVGYYG-DGCQLPCTCQNGADC 415
Query: 445 -PVKTPKICKPE-SGE--CINCLHNTTGFWCENCLE----GYVHDLEGNCIKKE------ 490
+ C P GE ++C T G C + G ++G+C KE
Sbjct: 416 HSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLD 475
Query: 491 VILPTPEGSTILVSNASLT 509
LP P G+ L N S T
Sbjct: 476 CTLPCPSGTWGLNCNESCT 494
Score = 90.1 bits (222), Expect = 6e-18
Identities = 80/259 (30%), Positives = 110/259 (42%), Gaps = 36/259 (13%)
Query: 242 NCSVVGSL-NVNRCNQTTGQCECRPGYQGLHCE-TCKEGFYLNYTSGLCQPCDCSPHGAL 299
NCSV S N C+ G CEC PG++G C+ C GF Y G QPC H
Sbjct: 574 NCSVSCSCENGGSCSPEDGSCECAPGFRGPLCQRICPPGF---YGHGCAQPCPLCVHS-- 628
Query: 300 SIPCNS-SGKCQCKVGVIGSICDR-CQDGYYGFSKNGCLPCQCNNRSASCDALTGACLNC 357
S PC+ SG C+C G G++C++ C GY+G ++ C C N + +C + G+C C
Sbjct: 629 SRPCHHISGICECLPGFSGALCNQVCAGGYFG--QDCAQLCSCAN-NGTCSPIDGSC-QC 684
Query: 358 QENSKGNHCEE-CKEGFYQSPDATKECL---RCPCSAVTSTGSCSIKSSELEPECDQ-CK 412
G C + C GF+ P C CSA G+C C Q C
Sbjct: 685 FPGWIGKDCSQACPPGFW-GPACFHACSCHNGASCSA--EDGACHCTPGWTGLFCTQRCP 741
Query: 413 DGYIGPNCNK---CENGYYNFDSICRKCQCHGHVDPVKTPKICKP--------ESGECIN 461
+ G +C + C+NG + D I KC C + C P + EC+N
Sbjct: 742 AAFFGKDCGRVCQCQNG-ASCDHISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQLCECMN 800
Query: 462 ---CLHNTTGFWCENCLEG 477
C H T +C +G
Sbjct: 801 NSTCDHVTGTCYCSPGFKG 819
Score = 87.8 bits (216), Expect = 3e-17
Identities = 66/242 (27%), Positives = 101/242 (41%), Gaps = 52/242 (21%)
Query: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALS 300
C+CS + + C+ TG C C G+ G+ C++ C P P+ ++S
Sbjct: 536 CDCS-----HADGCDPVTGHCCCLAGWTGIRCDST------------CPPGRWGPNCSVS 578
Query: 301 IPCNS-------SGKCQCKVGVIGSICDR-CQDGYYGFSKNGCL-PCQ-CNNRSASCDAL 350
C + G C+C G G +C R C G+YG +GC PC C + S C +
Sbjct: 579 CSCENGGSCSPEDGSCECAPGFRGPLCQRICPPGFYG---HGCAQPCPLCVHSSRPCHHI 635
Query: 351 TGACLNCQENSKGNHCEECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKSSELEPECDQ 410
+G C C G C + G Y D + C + + G+C S ++ C Q
Sbjct: 636 SGIC-ECLPGFSGALCNQVCAGGYFGQDCAQLC------SCANNGTC----SPIDGSC-Q 683
Query: 411 CKDGYIGPNCNK-CENGYYNFDSICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGF 469
C G+IG +C++ C G++ + C CH C E G C +C TG
Sbjct: 684 CFPGWIGKDCSQACPPGFWG-PACFHACSCHNGAS-------CSAEDGAC-HCTPGWTGL 734
Query: 470 WC 471
+C
Sbjct: 735 FC 736
Score = 79.0 bits (193), Expect = 1e-14
Identities = 73/224 (32%), Positives = 96/224 (42%), Gaps = 46/224 (20%)
Query: 261 CECRPGYQGLHCET-CKEGFYLNYTSGLCQPCDCSPHGALSIPCNSSGKCQCKVGVIGSI 319
C C PG+ G C + C + + S CQ +GAL P +G C C G G
Sbjct: 118 CHCEPGWGGPDCSSGCDSDHWGPHCSNRCQ----CQNGALCNPI--TGACVCAAGFRGWR 171
Query: 320 CDR-CQDGYYGFSKNGC-LPCQCNNRSASCDALTGACLNCQENSKGNHCEE-CKEGFYQS 376
C+ C G +G GC LPCQC + ASCD G CL C G +CEE C G + +
Sbjct: 172 CEELCAPGTHG---KGCQLPCQCRH-GASCDPRAGECL-CAPGYTGVYCEELCPPGSHGA 226
Query: 377 PDATKEC-LRCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNC-NKCENGYYNFDSIC 434
C LRCPC + G+C + EC C G+ G C C G + +
Sbjct: 227 -----HCELRCPCQ---NGGTC----HHITGEC-ACPPGWTGAVCAQPCPPGTFG-QNCS 272
Query: 435 RKCQCH--GHVDPVKTPKICKPESGECINCLHNTTGFWCENCLE 476
+ C CH G D V +G+C H T G+ + C E
Sbjct: 273 QDCPCHHGGQCDHV---------TGQC----HCTAGYMGDRCQE 303
Score = 46.6 bits (109), Expect = 7e-05
Identities = 27/84 (32%), Positives = 37/84 (44%), Gaps = 12/84 (14%)
Query: 240 VCNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCE-TCKEGFYLNYTSGLCQPCDCSPHGA 298
VC C N C+ +G+C CR G+ G HCE C G + G Q C+C +
Sbjct: 752 VCQCQ-----NGASCDHISGKCTCRTGFTGQHCEQRCAPG---TFGYGCQQLCECMNNST 803
Query: 299 LSIPCNSSGKCQCKVGVIGSICDR 322
+ +G C C G G CD+
Sbjct: 804 CD---HVTGTCYCSPGFKGIRCDQ 824
Score = 35.4 bits (80), Expect = 0.16
Identities = 12/36 (33%), Positives = 21/36 (58%), Gaps = 5/36 (13%)
Query: 238 EYVCNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCE 273
+ +C C +N + C+ TG C C PG++G+ C+
Sbjct: 793 QQLCEC-----MNNSTCDHVTGTCYCSPGFKGIRCD 823
>gi|122937343 platelet endothelial aggregation receptor 1 [Homo
sapiens]
Length = 1037
Score = 100 bits (248), Expect = 5e-21
Identities = 87/274 (31%), Positives = 108/274 (39%), Gaps = 63/274 (22%)
Query: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHC-ETCKEGFYLNYTSGLCQPCDCSPHGAL 299
C C N C++ TGQC C PGY G C E C G + + CDC+P A
Sbjct: 276 CRCH-----NGGLCDRFTGQCRCAPGYTGDRCREECPVG---RFGQDCAETCDCAP-DAR 326
Query: 300 SIPCNSSGKCQCKVGVIGSIC-DR-CQDGYYGFSKNGCLPCQCN-NRSASCDALTGACLN 356
P N G C C+ G G C DR C DG+YG S PC C+ S SC + G C +
Sbjct: 327 CFPAN--GACLCEHGFTGDRCTDRLCPDGFYGLSCQA--PCTCDREHSLSCHPMNGEC-S 381
Query: 357 CQENSKGNHCEECKEGFYQSPDATKECLRCPCSAV--TSTGSCSIKSSELEPECDQCKDG 414
C G HC E P + CL C V ++G C QC G
Sbjct: 382 CLPGWAGLHCNESCPQDTHGPGCQEHCL-CLHGGVCQATSGLC------------QCAPG 428
Query: 415 YIGPNC-NKCENGYYNFDSICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCEN 473
Y GP+C + C Y + R C C + C P GEC+
Sbjct: 429 YTGPHCASLCPPDTYGVNCSAR-CSCENAI-------ACSPIDGECV------------- 467
Query: 474 CLEGYVHDLEGNCIKKEVILPTPEGSTILVSNAS 507
C EG+ GNC +P P G+ NAS
Sbjct: 468 CKEGW---QRGNC-----SVPCPPGTWGFSCNAS 493
Score = 88.6 bits (218), Expect = 2e-17
Identities = 86/290 (29%), Positives = 112/290 (38%), Gaps = 80/290 (27%)
Query: 254 CNQTTGQCECRPGYQGLHCET-CKEGFYLNYTSGLCQPCD----CSPHGALSIPCNSSGK 308
C T+G C+C PGY G HC + C Y S C C+ CSP G+
Sbjct: 416 CQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCS-CENAIACSP---------IDGE 465
Query: 309 CQCKVGVIGSICD-RCQDGYYGFSKNGCLPCQCNNRSASCDALTGACLNCQENSKGNHCE 367
C CK G C C G +GFS N CQC + A C TGAC C G HC+
Sbjct: 466 CVCKEGWQRGNCSVPCPPGTWGFSCNA--SCQCAH-EAVCSPQTGAC-TCTPGWHGAHCQ 521
Query: 368 -ECKEGFYQSPDATK-EC----------LRCPCSA-----------------VTSTGSCS 398
C +G + A++ +C RC C A V + +C+
Sbjct: 522 LPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCT 581
Query: 399 IKS-SELEPECDQ--CKDGYIGPNCNK-CENGYYNFDSICRKCQCHGHVDPVKTPKICKP 454
K+ PE C G+ GP+C + C+ G Y C C+C H C P
Sbjct: 582 CKNGGTCLPENGNCVCAPGFRGPSCQRSCQPGRYG--KRCVPCKCANH-------SFCHP 632
Query: 455 ESGECINCLHNTT----------GFWCENCLE-------GYVHDLEGNCI 487
+G C CL T G W ENC + G H +G+CI
Sbjct: 633 SNGTCY-CLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDGSCI 681
Score = 72.4 bits (176), Expect = 1e-12
Identities = 73/251 (29%), Positives = 99/251 (39%), Gaps = 47/251 (18%)
Query: 260 QCECRPGYQGLHCET-CKEGFYLNYTSGLCQPCDCSPHGALSIPCNSSGKCQCKVGVIGS 318
QC+C PG++G C + C G + +PC C + + SG C C G+
Sbjct: 119 QCQCVPGWRGDDCSSECAPGMWGPQCD---KPCSCGNNSSCD---PKSGVCSCPSGLQPP 172
Query: 319 IC-DRCQDGYYGFSKNGCLPCQCNNRSASCDALTGACLNCQENSKGNHCE-ECKEGFYQS 376
C C GYYG + CQC+ A CD TGAC C G C+ C +G S
Sbjct: 173 NCLQPCTPGYYGPACQ--FRCQCHG--APCDPQTGACF-CPAERTGPSCDVSCSQG--TS 225
Query: 377 PDATKECLRCPCSAV--TSTGSCSIKSSELEPECD-QCKDGYIGPNCN---KCENGYY-- 428
C V T GSCS + C C +G+ GPNC+ +C NG
Sbjct: 226 GFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLCD 285
Query: 429 NFDSICR--------KCQ-----------CHGHVDPVKTPKICKPESGECINCLHNTTGF 469
F CR +C+ C D + C P +G C+ C H TG
Sbjct: 286 RFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDAR-CFPANGACL-CEHGFTGD 343
Query: 470 WCEN--CLEGY 478
C + C +G+
Sbjct: 344 RCTDRLCPDGF 354
Score = 65.9 bits (159), Expect = 1e-10
Identities = 45/143 (31%), Positives = 63/143 (44%), Gaps = 19/143 (13%)
Query: 235 VKTEYVCNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCE-TCKEGFYLNYTSGLCQPCDC 293
V C C N C G C C PG++G C+ +C+ G Y C PC C
Sbjct: 574 VNCSNTCTCK-----NGGTCLPENGNCVCAPGFRGPSCQRSCQPGRY----GKRCVPCKC 624
Query: 294 SPHGALSIPCNSSGKCQCKVGVIGSICDR-CQDGYYGFSKNGCLPCQCNNRSASCDALTG 352
+ H S S+G C C G G C + C G++G +N CQC++ +C G
Sbjct: 625 ANH---SFCHPSNGTCYCLAGWTGPDCSQPCPPGHWG--ENCAQTCQCHH-GGTCHPQDG 678
Query: 353 ACLNCQENSKGNHC-EECKEGFY 374
+C+ C G+HC E C G +
Sbjct: 679 SCI-CPLGWTGHHCLEGCPLGTF 700
>gi|93204871 netrin 4 [Homo sapiens]
Length = 628
Score = 98.6 bits (244), Expect = 2e-20
Identities = 63/195 (32%), Positives = 88/195 (45%), Gaps = 33/195 (16%)
Query: 192 PGHQWPVAKMPQKYL---GKYACESNLKSKYLPLTQPVMNLRVSEAVKTEY-------VC 241
P H + K P + GK C+ N + P+ N R EA + C
Sbjct: 273 PVHGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTC 332
Query: 242 NCSVVGS-----LNVNRC--NQTTGQCE-CRPGYQGLHCETCKEGFYLNY-----TSGLC 288
C+ +NV N++ G C+ C+ +G +C+ CK GFY + C
Sbjct: 333 KCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDAC 392
Query: 289 QPCDCSPHGALSIPCNS-------SGKCQCKVGVIGSICDRCQDGYYGFSKNGCLPCQCN 341
+PC C P G+ +P NS +G C CK GV G CDRC GY+GF GC PC C
Sbjct: 393 KPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDC- 451
Query: 342 NRSASCDALTGACLN 356
+ SCD +TG C++
Sbjct: 452 --AGSCDPITGDCIS 464
Score = 94.4 bits (233), Expect = 3e-19
Identities = 62/214 (28%), Positives = 86/214 (40%), Gaps = 54/214 (25%)
Query: 291 CDCSPHGALSIPCNS-------------SGKCQCKVGVIGSICDRCQ-----------DG 326
C C+ H IP + GKC CK GS C C DG
Sbjct: 262 CFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADG 321
Query: 327 YYGFSKNGCLPCQCNNRSASC-----------DALTGACLNCQENSKGNHCEECKEGFYQ 375
G + N C C+CN + +C + G C +CQ N++G +C+ CK GFY+
Sbjct: 322 KTG-APNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYR 380
Query: 376 -------SPDATKECLRCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGYY 428
+PDA K C P + + +C CK G G C++C GY+
Sbjct: 381 DLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDC-PCKPGVAGRRCDRCMVGYW 439
Query: 429 NF-DSICRKCQCHGHVDPVKTPKICKPESGECIN 461
F D CR C C G DP+ +G+CI+
Sbjct: 440 GFGDYGCRPCDCAGSCDPI---------TGDCIS 464
Score = 54.7 bits (130), Expect = 3e-07
Identities = 41/181 (22%), Positives = 62/181 (34%), Gaps = 35/181 (19%)
Query: 259 GQCECRPGYQGLHCETCKEGFY---------LNYTSGLCQPCDCSPHGAL---------S 300
G+C C+ G HC+ C + C+ C C+ H +
Sbjct: 291 GKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEA 350
Query: 301 IPCNSSGKCQ-CKVGVIGSICDRCQDGYYG------FSKNGCLPCQCN---------NRS 344
S G C C+ G C RC+ G+Y + + C PC C+ N
Sbjct: 351 SGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSV 410
Query: 345 ASCDALTGACLNCQENSKGNHCEECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKSSEL 404
CD G C C+ G C+ C G++ D C S TG C +++
Sbjct: 411 TFCDPSNGDC-PCKPGVAGRRCDRCMVGYWGFGDYGCRPCDCAGSCDPITGDCISSHTDI 469
Query: 405 E 405
+
Sbjct: 470 D 470
Score = 51.2 bits (121), Expect = 3e-06
Identities = 33/120 (27%), Positives = 47/120 (39%), Gaps = 9/120 (7%)
Query: 395 GSCSIKSSELEPECDQCKDGYIGPNCNKCENGYYNFDSICRKCQCHGHVDPVKTPKICKP 454
G C K + C C Y + +G + CR C+C+GH D
Sbjct: 291 GKCMCKHNTAGSHCQHCAPLY-NDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWE 349
Query: 455 ESGE-----CINCLHNTTGFWCENCLEGYVHDLEGNCIKKEVILPT---PEGSTILVSNA 506
SG C +C HNT G +C+ C G+ DL + P P GS +L +N+
Sbjct: 350 ASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANS 409
>gi|145701025 multiple EGF-like-domains 8 [Homo sapiens]
Length = 2778
Score = 93.6 bits (231), Expect = 5e-19
Identities = 69/249 (27%), Positives = 98/249 (39%), Gaps = 58/249 (23%)
Query: 254 CNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALSIPCNSSGKCQCKV 313
CN+T C G C +CK G+ ++ +GLC+P C+ G ++ C C+C
Sbjct: 2122 CNETQN---CHDQPHGYEC-SCKTGYTMDNMTGLCRPV-CA-QGCVNGSCVEPDHCRCHF 2175
Query: 314 GVIGSICDRCQDGYYGFSKNGCLPCQCNNRSASCDALTGA---CLNCQENSKGNHCEECK 370
G +G C C+CN R + C A GA CL C+ ++KG+HCE+C
Sbjct: 2176 GFVGRNCST--------------ECRCN-RHSEC-AGVGARDHCLLCRNHTKGSHCEQCL 2219
Query: 371 EGFYQSPDATKECLRCPCSAVTSTGSC-----------SIKSSELEPE------------ 407
F S C C ++ C K L+PE
Sbjct: 2220 PLFVGSAVGGGTCRPCHAFCRGNSHICISRKELQMSKGEPKKYSLDPEEIENWVTEGPSE 2279
Query: 408 ----CDQCKDGYIGPNCNKCENGYYNFDSICRKCQCHGHVDPVKTPKICKPESGECINCL 463
C C++ G C C GY+ D C KCQC+GH D C + G C
Sbjct: 2280 DEAVCVNCQNNSYGEKCESCLQGYFLLDGKCTKCQCNGHAD------TCNEQDGTGCPCQ 2333
Query: 464 HNTTGFWCE 472
+NT C+
Sbjct: 2334 NNTETGTCQ 2342
Score = 77.0 bits (188), Expect = 5e-14
Identities = 55/168 (32%), Positives = 71/168 (42%), Gaps = 47/168 (27%)
Query: 260 QCECRPGYQG---LHC-----ETCKEGFY-----------LNYTSGLCQP---------- 290
+C C+ GYQG HC E C G L +TS L P
Sbjct: 1032 ECHCQRGYQGDGISHCNRTCLEDCGHGVCSGPPDFTCVCDLGWTSDLPPPTPAPGPPAPR 1091
Query: 291 ----CDCSPHGALSIPCNSSGK--C-QCKVGVIGSICDRCQDGYYGFS--KNGCLPCQCN 341
C CS H C G C +C+ G C+RC+ G +G + GC PCQCN
Sbjct: 1092 CSRDCGCSFHSH----CRKRGPGFCDECQDWTWGEHCERCRPGSFGNATGSRGCRPCQCN 1147
Query: 342 N----RSASCDALTGACLNCQENSKGNHCEECKEGFYQSPDATKECLR 385
R CD L+G C CQ++++G HC+ C G+Y P A C R
Sbjct: 1148 GHGDPRRGHCDNLSGLCF-CQDHTEGAHCQLCSPGYYGDPRAGGSCFR 1194
Score = 55.1 bits (131), Expect = 2e-07
Identities = 31/87 (35%), Positives = 43/87 (49%), Gaps = 8/87 (9%)
Query: 408 CDQCKDGYIGPNCNKCENGYY---NFDSICRKCQCHGHVDPVKTPKICKPESGECINCLH 464
CD+C+D G +C +C G + CR CQC+GH DP + C SG C C
Sbjct: 1112 CDECQDWTWGEHCERCRPGSFGNATGSRGCRPCQCNGHGDPRRGH--CDNLSGLCF-CQD 1168
Query: 465 NTTGFWCENCLEGYVHD--LEGNCIKK 489
+T G C+ C GY D G+C ++
Sbjct: 1169 HTEGAHCQLCSPGYYGDPRAGGSCFRE 1195
Score = 52.4 bits (124), Expect = 1e-06
Identities = 40/172 (23%), Positives = 57/172 (33%), Gaps = 50/172 (29%)
Query: 263 CRPGYQGLHCETCKEGFYLNYTSG-LCQPCDCSPHGALSI-------------------- 301
CR +G HCE C F + G C+PC G I
Sbjct: 2206 CRNHTKGSHCEQCLPLFVGSAVGGGTCRPCHAFCRGNSHICISRKELQMSKGEPKKYSLD 2265
Query: 302 -----------PCNSSGKC-QCKVGVIGSICDRCQDGYYGFSKNGCLPCQCNNRSASCDA 349
P C C+ G C+ C GY+ C CQCN + +C+
Sbjct: 2266 PEEIENWVTEGPSEDEAVCVNCQNNSYGEKCESCLQGYF-LLDGKCTKCQCNGHADTCNE 2324
Query: 350 LTGACLNCQENSKGNHCE----------------ECKEGFYQSPDATKECLR 385
G CQ N++ C+ +C+E F+ SP ++C R
Sbjct: 2325 QDGTGCPCQNNTETGTCQGSSPSDRRDCYKYQCAKCRESFHGSPLGGQQCYR 2376
Score = 38.1 bits (87), Expect = 0.025
Identities = 13/40 (32%), Positives = 20/40 (50%)
Query: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFY 280
C C+ G C+ +G C C+ +G HC+ C G+Y
Sbjct: 1144 CQCNGHGDPRRGHCDNLSGLCFCQDHTEGAHCQLCSPGYY 1183
Score = 36.6 bits (83), Expect = 0.073
Identities = 23/68 (33%), Positives = 28/68 (41%), Gaps = 19/68 (27%)
Query: 256 QTTGQCECRPGYQGLHCETCKEGFYLNYTSGLCQPCD--CSPHGALSIPCNSSGKCQCKV 313
Q G C C PG+ G C GL Q C C HG + P G C+C+
Sbjct: 153 QPPGVCACEPGWGGPDC-------------GL-QECSAYCGSHGTCASPL---GPCRCEP 195
Query: 314 GVIGSICD 321
G +G CD
Sbjct: 196 GFLGRACD 203
Score = 31.2 bits (69), Expect = 3.1
Identities = 21/68 (30%), Positives = 24/68 (35%), Gaps = 12/68 (17%)
Query: 259 GQCECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALSIPCNSSGKCQCKVGVIGS 318
G C C G+ G HC LC P +C+ H S G C C G G
Sbjct: 1364 GLCRCPQGWAGPHCR-----------MALC-PENCNAHTGAGTCNQSLGVCICAEGFGGP 1411
Query: 319 ICDRCQDG 326
C DG
Sbjct: 1412 DCATKLDG 1419
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.130 0.416
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,164,582
Number of Sequences: 37866
Number of extensions: 2058428
Number of successful extensions: 48819
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 666
Number of HSP's successfully gapped in prelim test: 2045
Number of HSP's that attempted gapping in prelim test: 16305
Number of HSP's gapped (non-prelim): 16179
length of query: 639
length of database: 18,247,518
effective HSP length: 109
effective length of query: 530
effective length of database: 14,120,124
effective search space: 7483665720
effective search space used: 7483665720
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.