Search of human proteins with 29789405

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|29789405 hypothetical protein LOC284565 [Homo sapiens]
         (670 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|29789405 hypothetical protein LOC284565 [Homo sapiens]            1352   0.0  
gi|157266285 hypothetical protein LOC728936 [Homo sapiens]           1341   0.0  
gi|83415174 hypothetical protein LOC400818 [Homo sapiens]            1283   0.0  
gi|92110019 hypothetical protein LOC55672 [Homo sapiens]             1268   0.0  
gi|224589132 hypothetical protein LOC100132406 [Homo sapiens]        1211   0.0  
gi|169162915 PREDICTED: hypothetical protein LOC728841 [Homo sap...  1208   0.0  
gi|239741309 PREDICTED: hypothetical protein XP_002344485 [Homo ...  1204   0.0  
gi|7657017 hypothetical protein LOC25832 [Homo sapiens]              1084   0.0  
gi|156071420 hypothetical protein LOC728912 [Homo sapiens]            995   0.0  
gi|119709825 neuroblastoma breakpoint family, member 11-like [Ho...   995   0.0  
gi|14149997 neuroblastoma breakpoint family, member 3 [Homo sapi...   815   0.0  
gi|239741297 PREDICTED: neuroblastoma breakpoint family, member ...   530   e-150
gi|221136844 neuroblastoma breakpoint family, member 6 isoform 1...   479   e-135
gi|221218991 neuroblastoma breakpoint family, member 4 [Homo sap...   476   e-134
gi|221136848 neuroblastoma breakpoint family, member 6 isoform 2...   476   e-134
gi|114158664 hypothetical protein LOC343505 [Homo sapiens]            451   e-126
gi|239758011 PREDICTED: hypothetical protein LOC728841, partial ...   224   2e-58
gi|239747446 PREDICTED: similar to Neuroblastoma breakpoint fami...   119   9e-27
gi|239741304 PREDICTED: similar to Neuroblastoma breakpoint fami...   116   6e-26
gi|239741281 PREDICTED: Neuroblastoma breakpoint family member 6...   116   6e-26
gi|239752894 PREDICTED: Neuroblastoma breakpoint family member 6...   114   4e-25
gi|157311604 phosphodiesterase 4D interacting protein isoform 1 ...    80   5e-15
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li...    66   1e-10
gi|7657138 golgi integral membrane protein 4 [Homo sapiens]            62   2e-09
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...    59   2e-08
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho...    59   2e-08
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho...    59   2e-08
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho...    59   2e-08
gi|21735548 centrosomal protein 2 [Homo sapiens]                       55   3e-07
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li...    52   2e-06

>gi|29789405 hypothetical protein LOC284565 [Homo sapiens]
          Length = 670

 Score = 1352 bits (3500), Expect = 0.0
 Identities = 670/670 (100%), Positives = 670/670 (100%)

Query: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
           MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY
Sbjct: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60

Query: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120
           EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS
Sbjct: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120

Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180
           RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE
Sbjct: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180

Query: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240
           KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL
Sbjct: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240

Query: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP 300
           IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP
Sbjct: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP 300

Query: 301 PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV 360
           PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV
Sbjct: 301 PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV 360

Query: 361 LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSC 420
           LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSC
Sbjct: 361 LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSC 420

Query: 421 PRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDR 480
           PRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDR
Sbjct: 421 PRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDR 480

Query: 481 IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY 540
           IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY
Sbjct: 481 IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY 540

Query: 541 ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDDNPPCPRLYGVLMEVEE 600
           ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDDNPPCPRLYGVLMEVEE
Sbjct: 541 ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDDNPPCPRLYGVLMEVEE 600

Query: 601 PEVLQDSLDRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFALYVDNRFFTLTVTSLHL 660
           PEVLQDSLDRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFALYVDNRFFTLTVTSLHL
Sbjct: 601 PEVLQDSLDRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFALYVDNRFFTLTVTSLHL 660

Query: 661 VFQMGVIFPQ 670
           VFQMGVIFPQ
Sbjct: 661 VFQMGVIFPQ 670


>gi|157266285 hypothetical protein LOC728936 [Homo sapiens]
          Length = 670

 Score = 1341 bits (3470), Expect = 0.0
 Identities = 666/670 (99%), Positives = 666/670 (99%)

Query: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
           MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY
Sbjct: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60

Query: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120
           EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS
Sbjct: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120

Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180
           RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE
Sbjct: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180

Query: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240
           KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL
Sbjct: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240

Query: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP 300
           IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP
Sbjct: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP 300

Query: 301 PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV 360
           PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV
Sbjct: 301 PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV 360

Query: 361 LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSC 420
           LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSC
Sbjct: 361 LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSC 420

Query: 421 PRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDR 480
           PRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLAL VDR
Sbjct: 421 PRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDR 480

Query: 481 IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY 540
           IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY
Sbjct: 481 IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY 540

Query: 541 ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDDNPPCPRLYGVLMEVEE 600
           ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDDNPPCPRL GVLMEVEE
Sbjct: 541 ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDDNPPCPRLNGVLMEVEE 600

Query: 601 PEVLQDSLDRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFALYVDNRFFTLTVTSLHL 660
           PEVLQDSLDRCYST SMYFE PDSFQHYRSVFYSFEEEHISFALYVDNRFFTLTVTSLHL
Sbjct: 601 PEVLQDSLDRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFALYVDNRFFTLTVTSLHL 660

Query: 661 VFQMGVIFPQ 670
           VFQMGVIFPQ
Sbjct: 661 VFQMGVIFPQ 670


>gi|83415174 hypothetical protein LOC400818 [Homo sapiens]
          Length = 942

 Score = 1283 bits (3319), Expect = 0.0
 Identities = 644/671 (95%), Positives = 653/671 (97%), Gaps = 1/671 (0%)

Query: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
           MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLAN+Q KYKY
Sbjct: 272 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKY 331

Query: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120
           EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS
Sbjct: 332 EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 391

Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180
           RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRL QHLVQKLSPENDNDD+EDVQVEVAE
Sbjct: 392 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAE 451

Query: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240
           KVQKSSAPREMQKAEEKEVPEDSLEECAIT SNSHGPYDSNQPH+KTKITFEEDKVDSTL
Sbjct: 452 KVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTL 511

Query: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP 300
           IGSSSHVE EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYST SIP
Sbjct: 512 IGSSSHVEREDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTPSIP 571

Query: 301 PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV 360
           PEMLASY+SYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEK PEV
Sbjct: 572 PEMLASYKSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEV 631

Query: 361 LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSC 420
           LQDSL RCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLA+DMDEIEKYQEVEEDQDPSC
Sbjct: 632 LQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSC 691

Query: 421 PRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDR 480
           PRLSRELLDEKEPEVLQDSL R YSTPS Y ELPDLGQPYSSAVYSLEEQYLGLAL +DR
Sbjct: 692 PRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQPYSSAVYSLEEQYLGLALDLDR 751

Query: 481 IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY 540
           IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDS QPYGSSFY
Sbjct: 752 IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSWQPYGSSFY 811

Query: 541 ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVE 599
           ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGE+D NPPCPRL GVLMEVE
Sbjct: 812 ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVE 871

Query: 600 EPEVLQDSLDRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFALYVDNRFFTLTVTSLH 659
           EPEVLQDSLD CYSTPSMYFE PDSFQHYRSVFYSFEE+HISFALYVDNRFFTLTVTSLH
Sbjct: 872 EPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLH 931

Query: 660 LVFQMGVIFPQ 670
           LVFQM VIFPQ
Sbjct: 932 LVFQMEVIFPQ 942



 Score =  540 bits (1391), Expect = e-153
 Identities = 345/700 (49%), Positives = 431/700 (61%), Gaps = 78/700 (11%)

Query: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
           MVVSAGP SSEKAEMNILEINEKLRPQLAE KQQF NLKE+CFLTQLAGFLANRQKKYKY
Sbjct: 1   MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFLTQLAGFLANRQKKYKY 60

Query: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120
           EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVH+QERELTQL+EKLREGRDAS
Sbjct: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDAS 120

Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180
           RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRL QHLVQKLSPEND D+DEDVQVE  E
Sbjct: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDE 180

Query: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240
           KV +S APRE+QKAEE +V EDSLEECAITCSNSHGP DSNQPHK  KITFEED+V+STL
Sbjct: 181 KVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240

Query: 241 I--GSSSHVEWEDAVHIIP-----ENESDDEEEEEKGPVSPR----NLQESEEEEVPQES 289
           +    SSH E +DA++I+P      + ++       GP+S      N+ E  E+  PQ +
Sbjct: 241 VVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLA 300

Query: 290 WDEGYSTLSIPPE----MLASYQSYSSTFHSLEEQQVCMAVDIGRHRW---DQVKKEDQE 342
            ++     ++  +     LA + +     +  EE +  +   +   R    +++ ++ ++
Sbjct: 301 -EKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQ 359

Query: 343 ATGPRLSRELLDEKEPEV------LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQ-- 394
           A   R  + L+  +E E+      L++  D   S       L    +P +S    L++  
Sbjct: 360 AEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQL 419

Query: 395 -----------QRVGLAIDMDEIEKYQ--EVEEDQDPSCPRLSRELLDEKEPEVLQDSLD 441
                      Q++    D D+ E  Q    E+ Q  S P   RE+   +E EV +DSL+
Sbjct: 420 AEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAP---REMQKAEEKEVPEDSLE 476

Query: 442 RCYSTPSDYLELPDLGQPYSSAVYSLEEQ-----YLGLALAVDR---------IKKDQEE 487
            C  T S+     D  QP+     + EE       +G +  V+R          + D EE
Sbjct: 477 ECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEREDAVHIIPENESDDEE 536

Query: 488 EEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHV 547
           EE++GP  P   R L E  E EV Q+S D  YSTPS   E   S + Y S+F++LEE+ V
Sbjct: 537 EEEKGPVSP---RNLQESEEEEVPQESWDEGYSTPSIPPEMLASYKSYSSTFHSLEEQQV 593

Query: 548 GFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDDNPPCPRLYGVLMEVEEPEVLQDS 607
             ++D+G                  + R  + + ED     PRL   L++ + PEVLQDS
Sbjct: 594 CMAVDIG------------------RHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDS 635

Query: 608 LDRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFALYVD 647
           L RCYSTPS   E  DS Q YRS FY  E++ +  A+ +D
Sbjct: 636 LYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMD 675


>gi|92110019 hypothetical protein LOC55672 [Homo sapiens]
          Length = 1214

 Score = 1268 bits (3281), Expect = 0.0
 Identities = 634/672 (94%), Positives = 647/672 (96%), Gaps = 2/672 (0%)

Query: 1    MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
            MVVSAGPLSSEKAEMNILE+NEKLRPQLAEKKQQFRNLKEKCF+TQLA FLAN+Q KYKY
Sbjct: 543  MVVSAGPLSSEKAEMNILEMNEKLRPQLAEKKQQFRNLKEKCFVTQLACFLANQQNKYKY 602

Query: 61   EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120
            EECKDLIK +LRNERQFKEEKLAEQLKQAEELRQYKVLVH+QERELTQLREKLREGRDAS
Sbjct: 603  EECKDLIKSVLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 662

Query: 121  RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180
            RSLN+HLQALLTPDEPDKSQGQDLQEQLAEGCRL Q L QKLSPENDND DEDVQVEVAE
Sbjct: 663  RSLNQHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQQLFQKLSPENDNDHDEDVQVEVAE 722

Query: 181  KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240
            KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPH+KTKITFEEDKVDSTL
Sbjct: 723  KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 782

Query: 241  IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP 300
            IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP
Sbjct: 783  IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP 842

Query: 301  PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV 360
            PEMLASYQSYS TFHSLEEQQVCMAVDIG HRWDQVKKEDQEATGPRLSRELLDEK PEV
Sbjct: 843  PEMLASYQSYSGTFHSLEEQQVCMAVDIGGHRWDQVKKEDQEATGPRLSRELLDEKGPEV 902

Query: 361  LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSC 420
            LQDSLDRCYSTPSG LELTDSCQPYRSAFY+LEQQRVG A+DMDEIEKYQEVEEDQDPSC
Sbjct: 903  LQDSLDRCYSTPSGYLELTDSCQPYRSAFYILEQQRVGWALDMDEIEKYQEVEEDQDPSC 962

Query: 421  PRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDR 480
            PRLSRELLDEKEPEVLQDSLDRCYSTPS YLELPDLGQPY SAVYSLEEQYLGLAL VDR
Sbjct: 963  PRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYRSAVYSLEEQYLGLALDVDR 1022

Query: 481  IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY 540
            IKKDQEEEEDQGPPCPRLSRELLE VEPEVLQDSLDRCYSTPSSCLEQPDSC PYGSSFY
Sbjct: 1023 IKKDQEEEEDQGPPCPRLSRELLEAVEPEVLQDSLDRCYSTPSSCLEQPDSCLPYGSSFY 1082

Query: 541  ALEEKHVGFSLDVGEIEKKGKGKKRRGRRS-KKKRRRGRKEGEDD-NPPCPRLYGVLMEV 598
            ALEEKHVGFSLDVGEIEKKGKGKKRRGRRS KK+RRRGRKEGE+D NPPCPRL G+LMEV
Sbjct: 1083 ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSTKKRRRRGRKEGEEDQNPPCPRLSGMLMEV 1142

Query: 599  EEPEVLQDSLDRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFALYVDNRFFTLTVTSL 658
            EEPEVLQDSLDRCYSTPSMYFE PDSFQHYRSVFYSFEE+HISFAL VDNRF TL  TSL
Sbjct: 1143 EEPEVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALDVDNRFLTLMGTSL 1202

Query: 659  HLVFQMGVIFPQ 670
            HLVFQMGVIFPQ
Sbjct: 1203 HLVFQMGVIFPQ 1214



 Score =  550 bits (1416), Expect = e-156
 Identities = 350/699 (50%), Positives = 430/699 (61%), Gaps = 76/699 (10%)

Query: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
           MVVSAGPLSSEKAEMNILE+NEKLRPQLAEKKQQFRNLKEKCF+TQLAGFLAN+Q KYKY
Sbjct: 272 MVVSAGPLSSEKAEMNILEMNEKLRPQLAEKKQQFRNLKEKCFVTQLAGFLANQQNKYKY 331

Query: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120
           EEC+DLIK MLRNERQFKEEKLAEQLKQAEELRQYKVLVH+QERELTQLREKLREGRDAS
Sbjct: 332 EECEDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 391

Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180
           RSLN+HLQALLTPDEPDKSQGQDLQEQLAEGCRL QHLVQKLSPEND D+DEDVQVE AE
Sbjct: 392 RSLNQHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE 451

Query: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240
           KV +SSAPRE+QKAEE +VPEDSLEECAITCSNSHGP DSNQPHK   ITFEEDKV+S L
Sbjct: 452 KVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNINITFEEDKVNSAL 511

Query: 241 I--GSSSHVEWEDAVHIIP-----ENESDDEEEEEKGPVSPR----NLQESEEEEVPQ-E 288
           +    SSH E +DAV+I+P      + ++       GP+S      N+ E  E+  PQ  
Sbjct: 512 VVDRESSHDECQDAVNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEMNEKLRPQLA 571

Query: 289 SWDEGYSTLSIP--PEMLASYQSYSSTFHSLEE-QQVCMAVDIGRHRWDQVKKEDQ--EA 343
              + +  L        LA + +     +  EE + +  +V     ++ + K  +Q  +A
Sbjct: 572 EKKQQFRNLKEKCFVTQLACFLANQQNKYKYEECKDLIKSVLRNERQFKEEKLAEQLKQA 631

Query: 344 TGPRLSRELLDEKEPEV------LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQ-- 395
              R  + L+  +E E+      L++  D   S       L    +P +S    L++Q  
Sbjct: 632 EELRQYKVLVHSQERELTQLREKLREGRDASRSLNQHLQALLTPDEPDKSQGQDLQEQLA 691

Query: 396 ---RVGLAI----------DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDR 442
              R+   +          D DE  + +  E+ Q  S P   RE+   +E EV +DSL+ 
Sbjct: 692 EGCRLAQQLFQKLSPENDNDHDEDVQVEVAEKVQKSSAP---REMQKAEEKEVPEDSLEE 748

Query: 443 CYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLAL--------------AVDRIKKDQEEE 488
           C  T S+     D  QP+     + EE  +   L               +   + D EEE
Sbjct: 749 CAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEE 808

Query: 489 EDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVG 548
           E++GP  P   R L E  E EV Q+S D  YST S   E   S Q Y  +F++LEE+ V 
Sbjct: 809 EEKGPVSP---RNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSGTFHSLEEQQVC 865

Query: 549 FSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDDNPPCPRLYGVLMEVEEPEVLQDSL 608
            ++D+G            G R  + ++      ED     PRL   L++ + PEVLQDSL
Sbjct: 866 MAVDIG------------GHRWDQVKK------EDQEATGPRLSRELLDEKGPEVLQDSL 907

Query: 609 DRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFALYVD 647
           DRCYSTPS Y E  DS Q YRS FY  E++ + +AL +D
Sbjct: 908 DRCYSTPSGYLELTDSCQPYRSAFYILEQQRVGWALDMD 946



 Score =  466 bits (1199), Expect = e-131
 Identities = 285/524 (54%), Positives = 343/524 (65%), Gaps = 41/524 (7%)

Query: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
           MVVSAGP SSEKAE NILEINEKLRPQLAE KQQFRNLKEKCF+TQLAGFLANRQKKYKY
Sbjct: 1   MVVSAGPWSSEKAETNILEINEKLRPQLAENKQQFRNLKEKCFVTQLAGFLANRQKKYKY 60

Query: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120
           EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVH+QERELTQLREKLREGRDAS
Sbjct: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120

Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180
           RSLN+HLQALLTPDEPDKSQGQDLQEQLAEGCRL QHLVQKLSPEND D+DEDVQVE AE
Sbjct: 121 RSLNQHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE 180

Query: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240
           KV +SSAPRE+QKAEE +VPEDSLEECAITCSNSHGP DSNQPHK   ITFEEDKV+STL
Sbjct: 181 KVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNINITFEEDKVNSTL 240

Query: 241 I--GSSSHVEWEDAVHIIP-----ENESDDEEEEEKGPVSPR----NLQESEEEEVPQ-E 288
           +    SSH E +DAV+I+P      + ++       GP+S      N+ E  E+  PQ  
Sbjct: 241 VVDRESSHDECQDAVNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEMNEKLRPQLA 300

Query: 289 SWDEGYSTLSIP--PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRW---DQVKKEDQEA 343
              + +  L        LA + +     +  EE +  +   +   R    +++ ++ ++A
Sbjct: 301 EKKQQFRNLKEKCFVTQLAGFLANQQNKYKYEECEDLIKSMLRNERQFKEEKLAEQLKQA 360

Query: 344 TGPRLSRELLDEKEPEV------LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRV 397
              R  + L+  +E E+      L++  D   S       L    +P +S    L++Q  
Sbjct: 361 EELRQYKVLVHSQERELTQLREKLREGRDASRSLNQHLQALLTPDEPDKSQGQDLQEQLA 420

Query: 398 -GLAI--------------DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDR 442
            G  +              D DE  + +E E+  + S P   RE+   +E +V +DSL+ 
Sbjct: 421 EGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAP---REVQKAEESKVPEDSLEE 477

Query: 443 CYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQE 486
           C  T S+     D  QP+ +   + EE  +  AL VDR     E
Sbjct: 478 CAITCSNSHGPCDSNQPHKNINITFEEDKVNSALVVDRESSHDE 521



 Score = 35.8 bits (81), Expect = 0.13
 Identities = 40/162 (24%), Positives = 69/162 (42%), Gaps = 21/162 (12%)

Query: 404 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSA 463
           +E+ +Y+ +   Q+    +L  +L + ++         R  +     L  PD  +P  S 
Sbjct: 90  EELRQYKVLVHSQERELTQLREKLREGRDAS-------RSLNQHLQALLTPD--EPDKSQ 140

Query: 464 VYSLEEQYL-GLALA---VDRIKKDQEEEEDQGPPCPRLS--------RELLEVVEPEVL 511
              L+EQ   G  LA   V ++  + +E+ED+                RE+ +  E +V 
Sbjct: 141 GQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPREVQKAEESKVP 200

Query: 512 QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 553
           +DSL+ C  T S+     DS QP+ +     EE  V  +L V
Sbjct: 201 EDSLEECAITCSNSHGPCDSNQPHKNINITFEEDKVNSTLVV 242



 Score = 34.7 bits (78), Expect = 0.29
 Identities = 18/53 (33%), Positives = 31/53 (58%)

Query: 595 LMEVEEPEVLQDSLDRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFALYVD 647
           + + EE +V +DSL+ C  T S      DS Q ++++  +FEE+ ++  L VD
Sbjct: 191 VQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNINITFEEDKVNSTLVVD 243


>gi|224589132 hypothetical protein LOC100132406 [Homo sapiens]
          Length = 3628

 Score = 1211 bits (3132), Expect = 0.0
 Identities = 605/648 (93%), Positives = 620/648 (95%), Gaps = 1/648 (0%)

Query: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
           MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQL+GFLAN+QKKYKY
Sbjct: 272 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLSGFLANQQKKYKY 331

Query: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120
           EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQL+EKLREGRDAS
Sbjct: 332 EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDAS 391

Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180
           RSLNEHLQALLTP EPDKSQGQDLQEQLAEGCRL QHLVQKLSPENDNDDDEDVQVEVAE
Sbjct: 392 RSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE 451

Query: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240
           KVQKSSAPREMQKAEEKEVPEDSLEECAIT SNSHG YDSNQPH+KTKITFEEDKVDSTL
Sbjct: 452 KVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTL 511

Query: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP 300
           IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP
Sbjct: 512 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP 571

Query: 301 PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV 360
           PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEK PEV
Sbjct: 572 PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEV 631

Query: 361 LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSC 420
            QDS DRCYSTPSGCLELTDSCQPYRSAFY+LEQQRVGLAIDMDEIEKYQEVEEDQDPSC
Sbjct: 632 FQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAIDMDEIEKYQEVEEDQDPSC 691

Query: 421 PRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDR 480
           PRLSRELLDEKEPEVLQDSLDRCYSTPS YLELPDLGQPYSSAVYSLEEQYLGLAL VDR
Sbjct: 692 PRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR 751

Query: 481 IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY 540
           IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY
Sbjct: 752 IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY 811

Query: 541 ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVE 599
           ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGE+D NPPCPRL   L++ +
Sbjct: 812 ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEK 871

Query: 600 EPEVLQDSLDRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFALYVD 647
            PEVLQDSLDRCYSTPS   E  DS Q YRS FY  E++ + FA+ +D
Sbjct: 872 GPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMD 919



 Score =  606 bits (1563), Expect = e-173
 Identities = 331/505 (65%), Positives = 366/505 (72%), Gaps = 40/505 (7%)

Query: 169  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 673  DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 732

Query: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 733  SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVE 778

Query: 283  EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
             EV Q+S D  YST S   E   S Q Y S+F++LEE+ V  ++D+G             
Sbjct: 779  PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 838

Query: 330  ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
                  R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 839  RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 898

Query: 384  PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
            PYRSAFYVLEQQRVG A+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 899  PYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 958

Query: 444  YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELL 503
            YSTPS YLELPDLGQPYSSAVYSLEEQYLGLAL VDRIKKDQEEEEDQGPPCPRLSRELL
Sbjct: 959  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 1018

Query: 504  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 1019 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 1078

Query: 564  KRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQP 622
            KRRGRRSKK+RRRGRKEGE+D NPPCPRL   L++ + PEVLQDSLDRCYSTPS   E  
Sbjct: 1079 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 1138

Query: 623  DSFQHYRSVFYSFEEEHISFALYVD 647
            DS Q YRS FY  E++ + FA+ +D
Sbjct: 1139 DSCQPYRSAFYVLEQQRVGFAVDMD 1163



 Score =  606 bits (1563), Expect = e-173
 Identities = 331/505 (65%), Positives = 365/505 (72%), Gaps = 40/505 (7%)

Query: 169  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 2383 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2442

Query: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 2443 SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVE 2488

Query: 283  EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
             EV Q+S D  YST S   E   S Q Y S+F++LEE  V  ++D+G             
Sbjct: 2489 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 2548

Query: 330  ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
                  R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 2549 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 2608

Query: 384  PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
            PYRSAFYVLEQQ VGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 2609 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2668

Query: 444  YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELL 503
            YSTPS YLELPDLGQPYSSAVYSLEEQYLGLAL VDRIKKDQEEEEDQGPPCPRLSRELL
Sbjct: 2669 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 2728

Query: 504  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 2729 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 2788

Query: 564  KRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQP 622
            KRRGRRSKK+RRRGRKEGE+D NPPCPRL   L++ + PEVLQDSLDRCYSTPS   E  
Sbjct: 2789 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 2848

Query: 623  DSFQHYRSVFYSFEEEHISFALYVD 647
            DS Q YRS FY  E++H+  A+ +D
Sbjct: 2849 DSCQPYRSAFYVLEQQHVGLAVDMD 2873



 Score =  604 bits (1558), Expect = e-173
 Identities = 330/505 (65%), Positives = 364/505 (72%), Gaps = 40/505 (7%)

Query: 169  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 1651 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1710

Query: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 1711 SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVE 1756

Query: 283  EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
             EV Q+S D  YST S   E   S Q Y S+F++LEE  V  ++D+G             
Sbjct: 1757 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 1816

Query: 330  ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
                  R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 1817 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1876

Query: 384  PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
            PYRSAFYVLEQQ VGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 1877 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 1936

Query: 444  YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELL 503
            YSTPS YLELPDLGQPYSSAVYSLEEQYLGLAL VDRIKKDQEEEEDQGPPCPRLSRELL
Sbjct: 1937 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 1996

Query: 504  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEE HVGFSLDVGEIEKKGKGK
Sbjct: 1997 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGK 2056

Query: 564  KRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQP 622
            KRRGRRSKK+RRRGRKEGE+D NPPCPRL   L++ + PEVLQDSLDRCYSTPS   E  
Sbjct: 2057 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 2116

Query: 623  DSFQHYRSVFYSFEEEHISFALYVD 647
            DS Q YRS FY  E++H+  A+ +D
Sbjct: 2117 DSCQPYRSAFYVLEQQHVGLAVDMD 2141



 Score =  604 bits (1558), Expect = e-173
 Identities = 330/505 (65%), Positives = 364/505 (72%), Gaps = 40/505 (7%)

Query: 169  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 1895 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1954

Query: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 1955 SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVE 2000

Query: 283  EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
             EV Q+S D  YST S   E   S Q Y S+F++LEE  V  ++D+G             
Sbjct: 2001 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 2060

Query: 330  ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
                  R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 2061 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 2120

Query: 384  PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
            PYRSAFYVLEQQ VGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 2121 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2180

Query: 444  YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELL 503
            YSTPS YLELPDLGQPYSSAVYSLEEQYLGLAL VDRIKKDQEEEEDQGPPCPRLSRELL
Sbjct: 2181 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 2240

Query: 504  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEE HVGFSLDVGEIEKKGKGK
Sbjct: 2241 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGK 2300

Query: 564  KRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQP 622
            KRRGRRSKK+RRRGRKEGE+D NPPCPRL   L++ + PEVLQDSLDRCYSTPS   E  
Sbjct: 2301 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 2360

Query: 623  DSFQHYRSVFYSFEEEHISFALYVD 647
            DS Q YRS FY  E++H+  A+ +D
Sbjct: 2361 DSCQPYRSAFYVLEQQHVGLAVDMD 2385



 Score =  604 bits (1558), Expect = e-173
 Identities = 330/505 (65%), Positives = 364/505 (72%), Gaps = 40/505 (7%)

Query: 169  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 2139 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2198

Query: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 2199 SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVE 2244

Query: 283  EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
             EV Q+S D  YST S   E   S Q Y S+F++LEE  V  ++D+G             
Sbjct: 2245 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 2304

Query: 330  ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
                  R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 2305 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 2364

Query: 384  PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
            PYRSAFYVLEQQ VGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 2365 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2424

Query: 444  YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELL 503
            YSTPS YLELPDLGQPYSSAVYSLEEQYLGLAL VDRIKKDQEEEEDQGPPCPRLSRELL
Sbjct: 2425 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 2484

Query: 504  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEE HVGFSLDVGEIEKKGKGK
Sbjct: 2485 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGK 2544

Query: 564  KRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQP 622
            KRRGRRSKK+RRRGRKEGE+D NPPCPRL   L++ + PEVLQDSLDRCYSTPS   E  
Sbjct: 2545 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 2604

Query: 623  DSFQHYRSVFYSFEEEHISFALYVD 647
            DS Q YRS FY  E++H+  A+ +D
Sbjct: 2605 DSCQPYRSAFYVLEQQHVGLAVDMD 2629



 Score =  601 bits (1550), Expect = e-172
 Identities = 329/505 (65%), Positives = 365/505 (72%), Gaps = 40/505 (7%)

Query: 169  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 2627 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2686

Query: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 2687 SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVE 2732

Query: 283  EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
             EV Q+S D  YST S   E   S Q Y S+F++LEE+ V  ++D+G             
Sbjct: 2733 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 2792

Query: 330  ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
                  R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 2793 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 2852

Query: 384  PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
            PYRSAFYVLEQQ VGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 2853 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2912

Query: 444  YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELL 503
            YSTPS YLELPDLGQPYSSAVYSLEEQYLGLAL VDRIKKDQEEEEDQGPPCPRLSRELL
Sbjct: 2913 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 2972

Query: 504  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 2973 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 3032

Query: 564  KRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQP 622
            KRRGRRSKK+RRRGRKEGE+D NPPCPRL   L++ + P+VLQDSLDRCYSTPS   E  
Sbjct: 3033 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGCLELC 3092

Query: 623  DSFQHYRSVFYSFEEEHISFALYVD 647
            DS Q YRS FY  E++ +  A+ +D
Sbjct: 3093 DSCQPYRSAFYVLEQQRVGLAVDMD 3117



 Score =  600 bits (1548), Expect = e-171
 Identities = 329/505 (65%), Positives = 365/505 (72%), Gaps = 38/505 (7%)

Query: 169  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL  C  T S      D  QP+ 
Sbjct: 1405 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLNRCYSTPSGYLELPDLGQPYS 1464

Query: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
                + EE  +   L          D   I  + + ++EE+E++ P  PR    L E  E
Sbjct: 1465 SAVYSLEEQYLGLAL----------DVDRI--KKDQEEEEDEDQDPPCPRLSRELLEVVE 1512

Query: 283  EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
             EV Q+S D  YST S   E   S Q Y S+F++LEE  V  ++D+G             
Sbjct: 1513 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 1572

Query: 330  ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
                  R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 1573 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1632

Query: 384  PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
            PYRSAFYVLEQQ VGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 1633 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 1692

Query: 444  YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELL 503
            YSTPS YLELPDLGQPYSSAVYSLEEQYLGLAL VDRIKKDQEEEEDQGPPCPRLSRELL
Sbjct: 1693 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 1752

Query: 504  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEE HVGFSLDVGEIEKKGKGK
Sbjct: 1753 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGK 1812

Query: 564  KRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQP 622
            KRRGRRSKK+RRRGRKEGE+D NPPCPRL   L++ + PEVLQDSLDRCYSTPS   E  
Sbjct: 1813 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 1872

Query: 623  DSFQHYRSVFYSFEEEHISFALYVD 647
            DS Q YRS FY  E++H+  A+ +D
Sbjct: 1873 DSCQPYRSAFYVLEQQHVGLAVDMD 1897



 Score =  600 bits (1547), Expect = e-171
 Identities = 340/579 (58%), Positives = 400/579 (69%), Gaps = 36/579 (6%)

Query: 90   EELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPD---------EPDKSQ 140
            +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP          +P  S 
Sbjct: 2873 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 2932

Query: 141  GQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR---EMQKAEEK 197
               L+EQ   G  L    ++K     D +++ED         Q    PR   E+ +  E 
Sbjct: 2933 VYSLEEQYL-GLALDVDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEP 2977

Query: 198  EVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIP 257
            EV +DSL+ C  T S+     DS QP+  +    EE  V  +L       + +       
Sbjct: 2978 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGR 3037

Query: 258  ENESD-----DEEEEEKGPVSPRNLQESEEEEVP---QESWDEGYSTLSIPPEMLASYQS 309
             ++ +      E EE++ P  PR  +E  +E+ P   Q+S D  YST S   E+  S Q 
Sbjct: 3038 RSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGCLELCDSCQP 3097

Query: 310  YSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCY 369
            Y S F+ LE+Q+V +AVD+      Q  +EDQ+ + PRLSRELLDEK PEVLQDSLDRCY
Sbjct: 3098 YRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKGPEVLQDSLDRCY 3157

Query: 370  STPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLD 429
            STPSGCLEL DSCQPYRSAFY+LEQQRVGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLD
Sbjct: 3158 STPSGCLELCDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLD 3217

Query: 430  EKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEE 489
            EKEPEVLQDSLDRCYSTPS YLELPDLGQPYSSAVYSLEEQYLGLAL VDRIKKDQEEEE
Sbjct: 3218 EKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE 3277

Query: 490  DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF 549
            DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF
Sbjct: 3278 DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF 3337

Query: 550  SLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVEEPEVLQDSL 608
            SLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGE+D NPPCPRL   L++ + PEVLQDSL
Sbjct: 3338 SLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSL 3397

Query: 609  DRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFALYVD 647
            DRCYSTPS   E  DS Q YRS FY  E++H+  A+ +D
Sbjct: 3398 DRCYSTPSGCLELCDSCQPYRSAFYVLEQQHVGLAVDMD 3436



 Score =  598 bits (1541), Expect = e-171
 Identities = 327/505 (64%), Positives = 363/505 (71%), Gaps = 40/505 (7%)

Query: 169  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 917  DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 976

Query: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 977  SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVE 1022

Query: 283  EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
             EV Q+S D  YST S   E   S Q Y S+F++LEE+ V  ++D+G             
Sbjct: 1023 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 1082

Query: 330  ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
                  R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 1083 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1142

Query: 384  PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
            PYRSAFYVLEQQRVG A+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 1143 PYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 1202

Query: 444  YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELL 503
            YSTPS YLELPDLGQPYSSAVYSLEEQYLGLAL VDRIKKD+EEEEDQ PPCPRLSRELL
Sbjct: 1203 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELL 1262

Query: 504  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
            EVV PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 1263 EVVAPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 1322

Query: 564  KRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQP 622
            KRRGRRSKK+RRRGRKEGE+D NPPCPRL   L++ + PEVLQDSLDRCYSTPS   E  
Sbjct: 1323 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 1382

Query: 623  DSFQHYRSVFYSFEEEHISFALYVD 647
            DS Q YRS FY  E++ +  A+ +D
Sbjct: 1383 DSCQPYRSAFYVLEQQRVGMAVDMD 1407



 Score =  592 bits (1526), Expect = e-169
 Identities = 326/507 (64%), Positives = 364/507 (71%), Gaps = 42/507 (8%)

Query: 169  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 1161 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1220

Query: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
                + EE  +   L               +   + D+EEEE++ P  PR    L E   
Sbjct: 1221 SAVYSLEEQYLGLALD--------------VDRIKKDEEEEEDQDPPCPRLSRELLEVVA 1266

Query: 283  EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
             EV Q+S D  YST S   E   S Q Y S+F++LEE+ V  ++D+G             
Sbjct: 1267 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 1326

Query: 330  ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
                  R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 1327 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1386

Query: 384  PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
            PYRSAFYVLEQQRVG+A+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL+RC
Sbjct: 1387 PYRSAFYVLEQQRVGMAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLNRC 1446

Query: 444  YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEE--EDQGPPCPRLSRE 501
            YSTPS YLELPDLGQPYSSAVYSLEEQYLGLAL VDRIKKDQEEE  EDQ PPCPRLSRE
Sbjct: 1447 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDEDQDPPCPRLSRE 1506

Query: 502  LLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGK 561
            LLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEE HVGFSLDVGEIEKKGK
Sbjct: 1507 LLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGK 1566

Query: 562  GKKRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFE 620
            GKKRRGRRSKK+RRRGRKEGE+D NPPCPRL   L++ + PEVLQDSLDRCYSTPS   E
Sbjct: 1567 GKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLE 1626

Query: 621  QPDSFQHYRSVFYSFEEEHISFALYVD 647
              DS Q YRS FY  E++H+  A+ +D
Sbjct: 1627 LTDSCQPYRSAFYVLEQQHVGLAVDMD 1653



 Score =  568 bits (1465), Expect = e-162
 Identities = 317/528 (60%), Positives = 370/528 (70%), Gaps = 40/528 (7%)

Query: 169  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
            D DE  + +  E+ Q  S PR   E+   +  EV +DSL+ C  T S      DS QP++
Sbjct: 3115 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYR 3174

Query: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
                  E+ +V   +               + E E   E EE++ P  PR    L + +E
Sbjct: 3175 SAFYILEQQRVGLAVD--------------MDEIEKYQEVEEDQDPSCPRLSRELLDEKE 3220

Query: 283  EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQE 342
             EV Q+S D  YST S   E+    Q YSS  +SLEEQ + +A+D+ R + DQ ++EDQ 
Sbjct: 3221 PEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQG 3280

Query: 343  ATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAID 402
               PRLSRELL+  EPEVLQDSLDRCYSTPS CLE  DSCQPY S+FY LE++ VG ++D
Sbjct: 3281 PPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLD 3340

Query: 403  MDEIEKY-------------------QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
            + EIEK                    +E EEDQ+P CPRLSRELLDEK PEVLQDSLDRC
Sbjct: 3341 VGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRC 3400

Query: 444  YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELL 503
            YSTPS  LEL D  QPY SA Y LE+Q++GLA+ +D I+K QE EEDQ P CPRLSRELL
Sbjct: 3401 YSTPSGCLELCDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELL 3460

Query: 504  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
            +  EPEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE+++G +LDV +IEKKGKGK
Sbjct: 3461 DEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGK 3520

Query: 564  KRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQP 622
            KRRGRRSKK+RRRGRKEGE+D NPPCPRL GVLMEVEE EVLQDSLDRCYSTPSMYFE P
Sbjct: 3521 KRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELP 3580

Query: 623  DSFQHYRSVFYSFEEEHISFALYVDNRFFTLTVTSLHLVFQMGVIFPQ 670
            DSFQHYRSVFYSFEE+HISFALYVDNRFFTLTVTSLHLVFQMGVIFPQ
Sbjct: 3581 DSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMGVIFPQ 3628



 Score =  548 bits (1411), Expect = e-156
 Identities = 349/711 (49%), Positives = 420/711 (59%), Gaps = 100/711 (14%)

Query: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
           MVVSAGP SSEKAEMNILEINE LRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY
Sbjct: 1   MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60

Query: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120
           EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVH+QERELTQLREKLREGRDAS
Sbjct: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120

Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180
           RSL EHLQALLTPDEPDKSQGQDLQEQLAEGCRL QHLVQKLSPEND D+DEDVQVE AE
Sbjct: 121 RSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE 180

Query: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240
           KV +SSAPRE+QKAEE +VPEDSLEECAITCSNSHGP DSNQPHK  KITFEED+V+STL
Sbjct: 181 KVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240

Query: 241 I--GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLS 298
           +    SSH E +DA++I+P            GP S            P  S     + L 
Sbjct: 241 VVDRESSHDECQDALNILP----------VPGPTSSATNVSMVVSAGPLSSEKAEMNILE 290

Query: 299 IPPEMLASYQSYSSTFHSLEEQQVCMAVDIG--------RHRWDQVK------------- 337
           I  ++          F +L+E+  C    +         ++++++ K             
Sbjct: 291 INEKLRPQLAEKKQQFRNLKEK--CFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQF 348

Query: 338 KEDQEATGPRLSREL--------LDEKE----PEVLQDSLDRCYSTPSGCLELTDSCQPY 385
           KE++ A   + + EL          E+E     E L++  D   S       L    +P 
Sbjct: 349 KEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPD 408

Query: 386 RSAFYVLEQQRV-GLAI--------------DMDEIEKYQEVEEDQDPSCPRLSRELLDE 430
           +S    L++Q   G  +              D DE  + +  E+ Q  S P   RE+   
Sbjct: 409 KSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAP---REMQKA 465

Query: 431 KEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLAL-------------- 476
           +E EV +DSL+ C  T S+     D  QP+     + EE  +   L              
Sbjct: 466 EEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVH 525

Query: 477 AVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 536
            +   + D EEEE++GP  P   R L E  E EV Q+S D  YST S   E   S Q Y 
Sbjct: 526 IIPENESDDEEEEEKGPVSP---RNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYS 582

Query: 537 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDDNPPCPRLYGVLM 596
           S+F++LEE+ V  ++D+G                  + R  + + ED     PRL   L+
Sbjct: 583 STFHSLEEQQVCMAVDIG------------------RHRWDQVKKEDQEATGPRLSRELL 624

Query: 597 EVEEPEVLQDSLDRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFALYVD 647
           + + PEV QDS DRCYSTPS   E  DS Q YRS FY  E++ +  A+ +D
Sbjct: 625 DEKGPEVFQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAIDMD 675


>gi|169162915 PREDICTED: hypothetical protein LOC728841 [Homo
           sapiens]
          Length = 3815

 Score = 1208 bits (3125), Expect = 0.0
 Identities = 602/648 (92%), Positives = 619/648 (95%), Gaps = 1/648 (0%)

Query: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
           MVVSAGPLSSEKAEMNILEINEKL PQLAEKKQQFRNLKE+CF+TQLAGFLAN+QKKYKY
Sbjct: 21  MVVSAGPLSSEKAEMNILEINEKLHPQLAEKKQQFRNLKERCFVTQLAGFLANQQKKYKY 80

Query: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120
           EECKDLIK MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS
Sbjct: 81  EECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 140

Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180
           RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRL QHLVQKLSPENDNDDDEDVQVE+AE
Sbjct: 141 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVELAE 200

Query: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240
           KVQKSSAPREMQKAEEKEVPEDS EECAIT SNSHGPYDSNQPH+KTKITFEEDKVDSTL
Sbjct: 201 KVQKSSAPREMQKAEEKEVPEDSQEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTL 260

Query: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP 300
           IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP
Sbjct: 261 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP 320

Query: 301 PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV 360
           PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEK PEV
Sbjct: 321 PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEV 380

Query: 361 LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSC 420
           LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQR+GLA+DMDEIEKYQEVEEDQDPSC
Sbjct: 381 LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRIGLAVDMDEIEKYQEVEEDQDPSC 440

Query: 421 PRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDR 480
           PRLSRELLDEKEPEVLQDSLDRCYSTPS YLELPDLGQPYSSAVYSLEEQYLGLAL VDR
Sbjct: 441 PRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR 500

Query: 481 IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY 540
            KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY
Sbjct: 501 TKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY 560

Query: 541 ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVE 599
           ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGE+D NPPCPRL   L++ +
Sbjct: 561 ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEK 620

Query: 600 EPEVLQDSLDRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFALYVD 647
            PEVLQDSLDRCYSTPS   E  DS Q YRS FY  E++ +  A+ +D
Sbjct: 621 GPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMD 668



 Score =  612 bits (1579), Expect = e-175
 Identities = 334/505 (66%), Positives = 367/505 (72%), Gaps = 40/505 (7%)

Query: 169 DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
           D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 422 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 481

Query: 226 KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
               + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 482 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 527

Query: 283 EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
            EV Q+S D  YST S   E   S Q Y S+F++LEE+ V  ++D+G             
Sbjct: 528 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 587

Query: 330 ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
                 R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 588 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 647

Query: 384 PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
           PYRSAFYVLEQQRVGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 648 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 707

Query: 444 YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELL 503
           YSTPS YLELPDLGQPYSSAVYSLEEQYLGLAL VDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 708 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 767

Query: 504 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
           EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 768 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 827

Query: 564 KRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQP 622
           KRRGRRSKK+RRRGRKEGE+D NPPCPRL   L++ +EPEVLQDSLDRCYSTPS Y E P
Sbjct: 828 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELP 887

Query: 623 DSFQHYRSVFYSFEEEHISFALYVD 647
           D  Q Y S  YS EE+++  AL VD
Sbjct: 888 DLGQPYSSAVYSLEEQYLGLALDVD 912



 Score =  612 bits (1579), Expect = e-175
 Identities = 334/505 (66%), Positives = 367/505 (72%), Gaps = 40/505 (7%)

Query: 169  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 2149 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2208

Query: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 2209 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 2254

Query: 283  EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
             EV Q+S D  YST S   E   S Q Y S+F++LEE+ V  ++D+G             
Sbjct: 2255 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 2314

Query: 330  ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
                  R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 2315 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 2374

Query: 384  PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
            PYRSAFYVLEQQRVGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 2375 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2434

Query: 444  YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELL 503
            YSTPS YLELPDLGQPYSSAVYSLEEQYLGLAL VDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 2435 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 2494

Query: 504  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 2495 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 2554

Query: 564  KRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQP 622
            KRRGRRSKK+RRRGRKEGE+D NPPCPRL   L++ +EPEVLQDSLDRCYSTPS Y E P
Sbjct: 2555 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELP 2614

Query: 623  DSFQHYRSVFYSFEEEHISFALYVD 647
            D  Q Y S  YS EE+++  AL VD
Sbjct: 2615 DLGQPYSSAVYSLEEQYLGLALDVD 2639



 Score =  608 bits (1567), Expect = e-174
 Identities = 327/482 (67%), Positives = 357/482 (74%), Gaps = 37/482 (7%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVE 248
            RE+   +E EV +DSL+ C  T S      D  QP+     + EE  +   L        
Sbjct: 2585 RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD------- 2637

Query: 249  WEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPEMLA 305
                   +   + D EEEE++GP  PR    L E  E EV Q+S D  YST S   E   
Sbjct: 2638 -------VDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPD 2690

Query: 306  SYQSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVKKEDQEATGP 346
            S Q Y S+F++LEE+ V  ++D+G                   R R  +  +EDQ    P
Sbjct: 2691 SCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCP 2750

Query: 347  RLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEI 406
            RLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLA+DMDEI
Sbjct: 2751 RLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEI 2810

Query: 407  EKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYS 466
            EKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPS YLELPDLGQPYSSAVYS
Sbjct: 2811 EKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYS 2870

Query: 467  LEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 526
            LEEQYLGLAL VDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL
Sbjct: 2871 LEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 2930

Query: 527  EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDD-N 585
            EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGE+D N
Sbjct: 2931 EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN 2990

Query: 586  PPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFALY 645
            PPCPRL   L++ +EPEVLQDSLDRCYSTPS Y E PD  Q Y S  YS EE+++  AL 
Sbjct: 2991 PPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD 3050

Query: 646  VD 647
            VD
Sbjct: 3051 VD 3052



 Score =  603 bits (1554), Expect = e-172
 Identities = 324/494 (65%), Positives = 360/494 (72%), Gaps = 37/494 (7%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVE 248
            RE+   +E EV +DSL+ C  T S      D  QP+     + EE  +   L        
Sbjct: 3336 RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD------- 3388

Query: 249  WEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPEMLA 305
                   +   + D EEEE++GP  PR    L E  E EV Q+S D  YST S   E   
Sbjct: 3389 -------VDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPD 3441

Query: 306  SYQSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVKKEDQEATGP 346
            S Q Y S+F++LEE+ V  ++D+G                   R R  +  +EDQ    P
Sbjct: 3442 SCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCP 3501

Query: 347  RLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEI 406
            RLSRELLDEK PEVLQDSLDR YSTPSGCLELTDSCQPYRSAFYVLEQQRVGLA+DMDEI
Sbjct: 3502 RLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEI 3561

Query: 407  EKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYS 466
            EKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPS YLELPDLGQPYSSAVYS
Sbjct: 3562 EKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYS 3621

Query: 467  LEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 526
            LEEQYLGLAL VDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL
Sbjct: 3622 LEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 3681

Query: 527  EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDD-N 585
            EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGE+D N
Sbjct: 3682 EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN 3741

Query: 586  PPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFALY 645
            PPCPRL   L++ + PEVLQDSLDRCYSTPS   E  DS Q YRS FY  E++ +  A+ 
Sbjct: 3742 PPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVD 3801

Query: 646  VDNRFFTLTVTSLH 659
            +D  + ++ V  +H
Sbjct: 3802 MDGEYLSMKVIRIH 3815



 Score =  601 bits (1549), Expect = e-172
 Identities = 329/505 (65%), Positives = 364/505 (72%), Gaps = 40/505 (7%)

Query: 169  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 1661 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1720

Query: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 1721 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 1766

Query: 283  EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
             EV Q+S D  YST S   E   S Q Y S+F++LEE+ V  ++D+G             
Sbjct: 1767 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 1826

Query: 330  ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
                  R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 1827 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1886

Query: 384  PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
            PYRSAFYVLEQQRVGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 1887 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 1946

Query: 444  YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELL 503
            YSTPS YLELPDLGQPYSSAVYSLEEQYLGLAL VDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 1947 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 2006

Query: 504  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 2007 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 2066

Query: 564  KRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQP 622
            KRRGRRSKK+RRRGRKEGE+D NPPCPRL   L++ + PEVLQDSLDR YSTPS   E  
Sbjct: 2067 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELT 2126

Query: 623  DSFQHYRSVFYSFEEEHISFALYVD 647
            DS Q YRS FY  E++ +  A+ +D
Sbjct: 2127 DSCQPYRSAFYVLEQQRVGLAVDMD 2151



 Score =  601 bits (1549), Expect = e-172
 Identities = 329/505 (65%), Positives = 364/505 (72%), Gaps = 40/505 (7%)

Query: 169  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 1905 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1964

Query: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 1965 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 2010

Query: 283  EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
             EV Q+S D  YST S   E   S Q Y S+F++LEE+ V  ++D+G             
Sbjct: 2011 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 2070

Query: 330  ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
                  R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTPSGCLELTDSCQ
Sbjct: 2071 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQ 2130

Query: 384  PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
            PYRSAFYVLEQQRVGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 2131 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2190

Query: 444  YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELL 503
            YSTPS YLELPDLGQPYSSAVYSLEEQYLGLAL VDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 2191 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 2250

Query: 504  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 2251 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 2310

Query: 564  KRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQP 622
            KRRGRRSKK+RRRGRKEGE+D NPPCPRL   L++ + PEVLQDSLDRCYSTPS   E  
Sbjct: 2311 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 2370

Query: 623  DSFQHYRSVFYSFEEEHISFALYVD 647
            DS Q YRS FY  E++ +  A+ +D
Sbjct: 2371 DSCQPYRSAFYVLEQQRVGLAVDMD 2395



 Score =  600 bits (1547), Expect = e-171
 Identities = 323/482 (67%), Positives = 355/482 (73%), Gaps = 37/482 (7%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVE 248
            RE+   +E EV +DSL+ C  T S      D  QP+     + EE  +   L        
Sbjct: 1440 RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD------- 1492

Query: 249  WEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPEMLA 305
                   +   + D EEEE++GP  PR    L E  E EV Q+S D  YST S   E   
Sbjct: 1493 -------VDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPD 1545

Query: 306  SYQSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVKKEDQEATGP 346
            S Q Y S+F++LEE+ V  ++D+G                   R R  +  +EDQ    P
Sbjct: 1546 SCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCP 1605

Query: 347  RLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEI 406
            RLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLA+DMDEI
Sbjct: 1606 RLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEI 1665

Query: 407  EKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYS 466
            EKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPS YLELPDLGQPYSSAVYS
Sbjct: 1666 EKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYS 1725

Query: 467  LEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 526
            LEEQYLGLAL VDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL
Sbjct: 1726 LEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 1785

Query: 527  EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDD-N 585
            EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGE+D N
Sbjct: 1786 EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN 1845

Query: 586  PPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFALY 645
            PPCPRL   L++ + PEVLQDSLDRCYSTPS   E  DS Q YRS FY  E++ +  A+ 
Sbjct: 1846 PPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVD 1905

Query: 646  VD 647
            +D
Sbjct: 1906 MD 1907



 Score =  587 bits (1514), Expect = e-168
 Identities = 324/505 (64%), Positives = 360/505 (71%), Gaps = 40/505 (7%)

Query: 169  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 666  DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 725

Query: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 726  SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 771

Query: 283  EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
             EV Q+S D  YST S   E   S Q Y S+F++LEE+ V  ++D+G             
Sbjct: 772  PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 831

Query: 330  ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
                  R R  +  +EDQ    PRLSRELLDEKEPEVLQDSLDRCYSTPSG LEL D  Q
Sbjct: 832  RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQ 891

Query: 384  PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
            PY SA Y LE+Q +GLA+D+DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 892  PYSSAVYSLEEQYLGLALDVDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 951

Query: 444  YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELL 503
            YSTPS YLELPDLGQPYSSAVYSLEEQYLGLAL VDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 952  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 1011

Query: 504  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 1012 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 1071

Query: 564  KRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQP 622
            KRRGRRSKK+RRRGRKEGE+D NPPCPRL   L++ +EPEVLQDSLDRCYSTPS Y E P
Sbjct: 1072 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELP 1131

Query: 623  DSFQHYRSVFYSFEEEHISFALYVD 647
            D  Q Y S  YS EE+++  AL VD
Sbjct: 1132 DLGQPYSSAVYSLEEQYLGLALDVD 1156



 Score =  561 bits (1445), Expect = e-160
 Identities = 306/482 (63%), Positives = 345/482 (71%), Gaps = 37/482 (7%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVE 248
            RE+   +E EV +DSL+ C  T S      D  QP+     + EE  +   L        
Sbjct: 858  RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD------- 910

Query: 249  WEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPEMLA 305
                   + E E   E EE++ P  PR    L + +E EV Q+S D  YST S   E+  
Sbjct: 911  -------VDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPD 963

Query: 306  SYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSL 365
              Q YSS  +SLEEQ + +A+D+ R + DQ ++EDQ    PRLSRELL+  EPEVLQDSL
Sbjct: 964  LGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSL 1023

Query: 366  DRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKY---------------- 409
            DRCYSTPS CLE  DSCQPY S+FY LE++ VG ++D+ EIEK                 
Sbjct: 1024 DRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERR 1083

Query: 410  ---QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYS 466
               +E EEDQ+P CPRLSRELLDEKEPEVLQDSLDRCYSTPS YLELPDLGQPYSSAVYS
Sbjct: 1084 RGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYS 1143

Query: 467  LEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 526
            LEEQYLGLAL VDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL
Sbjct: 1144 LEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 1203

Query: 527  EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDD-N 585
            EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGE+D N
Sbjct: 1204 EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN 1263

Query: 586  PPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFALY 645
            PPCPRL   L++ +EPEVLQDSLDRCYSTPS Y E PD  Q Y S  YS EE+++  AL 
Sbjct: 1264 PPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD 1323

Query: 646  VD 647
            VD
Sbjct: 1324 VD 1325



 Score =  560 bits (1442), Expect = e-159
 Identities = 327/604 (54%), Positives = 390/604 (64%), Gaps = 45/604 (7%)

Query: 79   EEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTP----D 134
            EE+        +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP    +
Sbjct: 901  EEQYLGLALDVDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLE 960

Query: 135  EPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR---EM 191
             PD  Q         E     Q+L   L  +    D E+      E+ Q    PR   E+
Sbjct: 961  LPDLGQPYSSAVYSLE----EQYLGLALDVDRTKKDQEE------EEDQGPPCPRLSREL 1010

Query: 192  QKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVEWED 251
             +  E EV +DSL+ C  T S+     DS QP+  +    EE  V  +L       + + 
Sbjct: 1011 LEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKG 1070

Query: 252  AVHIIPENESD-----DEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPEM 303
                   ++ +      E EE++ P  PR    L + +E EV Q+S D  YST S   E+
Sbjct: 1071 KKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLEL 1130

Query: 304  LASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQD 363
                Q YSS  +SLEEQ + +A+D+ R + DQ ++EDQ    PRLSRELL+  EPEVLQD
Sbjct: 1131 PDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQD 1190

Query: 364  SLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKY-------------- 409
            SLDRCYSTPS CLE  DSCQPY S+FY LE++ VG ++D+ EIEK               
Sbjct: 1191 SLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKE 1250

Query: 410  -----QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAV 464
                 +E EEDQ+P CPRLSRELLDEKEPEVLQDSLDRCYSTPS YLELPDLGQPYSSAV
Sbjct: 1251 RRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAV 1310

Query: 465  YSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSS 524
            YSLEEQYLGLAL VDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSS
Sbjct: 1311 YSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSS 1370

Query: 525  CLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDD 584
            CLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGE+D
Sbjct: 1371 CLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEED 1430

Query: 585  -NPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFA 643
             NPPCPRL   L++ +EPEVLQDSLDRCYSTPS Y E PD  Q Y S  YS EE+++  A
Sbjct: 1431 QNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLA 1490

Query: 644  LYVD 647
            L VD
Sbjct: 1491 LDVD 1494



 Score =  560 bits (1442), Expect = e-159
 Identities = 305/482 (63%), Positives = 346/482 (71%), Gaps = 37/482 (7%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVE 248
            RE+   +  EV +DSL+ C  T S      DS QP++      E+ +V   +        
Sbjct: 2754 RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVD------- 2806

Query: 249  WEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPEMLA 305
                   + E E   E EE++ P  PR    L + +E EV Q+S D  YST S   E+  
Sbjct: 2807 -------MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPD 2859

Query: 306  SYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSL 365
              Q YSS  +SLEEQ + +A+D+ R + DQ ++EDQ    PRLSRELL+  EPEVLQDSL
Sbjct: 2860 LGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSL 2919

Query: 366  DRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKY---------------- 409
            DRCYSTPS CLE  DSCQPY S+FY LE++ VG ++D+ EIEK                 
Sbjct: 2920 DRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERR 2979

Query: 410  ---QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYS 466
               +E EEDQ+P CPRLSRELLDEKEPEVLQDSLDRCYSTPS YLELPDLGQPYSSAVYS
Sbjct: 2980 RGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYS 3039

Query: 467  LEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 526
            LEEQYLGLAL VDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL
Sbjct: 3040 LEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 3099

Query: 527  EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDD-N 585
            EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGE+D N
Sbjct: 3100 EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN 3159

Query: 586  PPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFALY 645
            PPCPRL   L++ +EPEVLQDSLDRCYSTPS Y E PD  Q Y S  YS EE+++  AL 
Sbjct: 3160 PPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD 3219

Query: 646  VD 647
            VD
Sbjct: 3220 VD 3221



 Score =  559 bits (1440), Expect = e-159
 Identities = 306/487 (62%), Positives = 350/487 (71%), Gaps = 28/487 (5%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVE 248
            RE+ +  E EV +DSL+ C  T S+     DS QP+  +    EE  V  +L       +
Sbjct: 2904 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKK 2963

Query: 249  WEDAVHIIPENESD-----DEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIP 300
             +        ++ +      E EE++ P  PR    L + +E EV Q+S D  YST S  
Sbjct: 2964 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGY 3023

Query: 301  PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV 360
             E+    Q YSS  +SLEEQ + +A+D+ R + DQ ++EDQ    PRLSRELL+  EPEV
Sbjct: 3024 LELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEV 3083

Query: 361  LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKY----------- 409
            LQDSLDRCYSTPS CLE  DSCQPY S+FY LE++ VG ++D+ EIEK            
Sbjct: 3084 LQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRS 3143

Query: 410  --------QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYS 461
                    +E EEDQ+P CPRLSRELLDEKEPEVLQDSLDRCYSTPS YLELPDLGQPYS
Sbjct: 3144 KKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 3203

Query: 462  SAVYSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYST 521
            SAVYSLEEQYLGLAL VDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYST
Sbjct: 3204 SAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYST 3263

Query: 522  PSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEG 581
            PSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEG
Sbjct: 3264 PSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEG 3323

Query: 582  EDD-NPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHI 640
            E+D NPPCPRL   L++ +EPEVLQDSLDRCYSTPS Y E PD  Q Y S  YS EE+++
Sbjct: 3324 EEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYL 3383

Query: 641  SFALYVD 647
              AL VD
Sbjct: 3384 GLALDVD 3390



 Score =  552 bits (1422), Expect = e-157
 Identities = 301/482 (62%), Positives = 344/482 (71%), Gaps = 37/482 (7%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVE 248
            RE+   +  EV +DSL+ C  T S      DS QP++      E+ +V   +        
Sbjct: 2341 RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVD------- 2393

Query: 249  WEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPEMLA 305
                   + E E   E EE++ P  PR    L + +E EV Q+S D  YST S   E+  
Sbjct: 2394 -------MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPD 2446

Query: 306  SYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSL 365
              Q YSS  +SLEEQ + +A+D+ R + DQ ++EDQ    PRLSRELL+  EPEVLQDSL
Sbjct: 2447 LGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSL 2506

Query: 366  DRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKY---------------- 409
            DRCYSTPS CLE  DSCQPY S+FY LE++ VG ++D+ EIEK                 
Sbjct: 2507 DRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERR 2566

Query: 410  ---QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYS 466
               +E EEDQ+P CPRLSRELLDEKEPEVLQDSLDRCYSTPS YLELPDLGQPYSSAVYS
Sbjct: 2567 RGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYS 2626

Query: 467  LEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 526
            LEEQYLGLAL VDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL
Sbjct: 2627 LEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 2686

Query: 527  EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDD-N 585
            EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGE+D N
Sbjct: 2687 EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN 2746

Query: 586  PPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFALY 645
            PPCPRL   L++ + PEVLQDSLDRCYSTPS   E  DS Q YRS FY  E++ +  A+ 
Sbjct: 2747 PPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVD 2806

Query: 646  VD 647
            +D
Sbjct: 2807 MD 2808



 Score =  551 bits (1420), Expect = e-157
 Identities = 302/487 (62%), Positives = 348/487 (71%), Gaps = 28/487 (5%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVE 248
            RE+ +  E EV +DSL+ C  T S+     DS QP+  +    EE  V  +L       +
Sbjct: 1177 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKK 1236

Query: 249  WEDAVHIIPENESD-----DEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIP 300
             +        ++ +      E EE++ P  PR    L + +E EV Q+S D  YST S  
Sbjct: 1237 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGY 1296

Query: 301  PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV 360
             E+    Q YSS  +SLEEQ + +A+D+ R + DQ ++EDQ    PRLSRELL+  EPEV
Sbjct: 1297 LELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEV 1356

Query: 361  LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKY----------- 409
            LQDSLDRCYSTPS CLE  DSCQPY S+FY LE++ VG ++D+ EIEK            
Sbjct: 1357 LQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRS 1416

Query: 410  --------QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYS 461
                    +E EEDQ+P CPRLSRELLDEKEPEVLQDSLDRCYSTPS YLELPDLGQPYS
Sbjct: 1417 KKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1476

Query: 462  SAVYSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYST 521
            SAVYSLEEQYLGLAL VDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYST
Sbjct: 1477 SAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYST 1536

Query: 522  PSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEG 581
            PSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEG
Sbjct: 1537 PSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEG 1596

Query: 582  EDD-NPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHI 640
            E+D NPPCPRL   L++ + PEVLQDSLDRCYSTPS   E  DS Q YRS FY  E++ +
Sbjct: 1597 EEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRV 1656

Query: 641  SFALYVD 647
              A+ +D
Sbjct: 1657 GLAVDMD 1663



 Score =  547 bits (1410), Expect = e-155
 Identities = 301/487 (61%), Positives = 347/487 (71%), Gaps = 28/487 (5%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVE 248
            RE+ +  E EV +DSL+ C  T S+     DS QP+  +    EE  V  +L       +
Sbjct: 3073 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKK 3132

Query: 249  WEDAVHIIPENESD-----DEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIP 300
             +        ++ +      E EE++ P  PR    L + +E EV Q+S D  YST S  
Sbjct: 3133 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGY 3192

Query: 301  PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV 360
             E+    Q YSS  +SLEEQ + +A+D+ R + DQ ++EDQ    PRLSRELL+  EPEV
Sbjct: 3193 LELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEV 3252

Query: 361  LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKY----------- 409
            LQDSLDRCYSTPS CLE  DSCQPY S+FY LE++ VG ++D+ EIEK            
Sbjct: 3253 LQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRS 3312

Query: 410  --------QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYS 461
                    +E EEDQ+P CPRLSRELLDEKEPEVLQDSLDRCYSTPS YLELPDLGQPYS
Sbjct: 3313 KKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 3372

Query: 462  SAVYSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYST 521
            SAVYSLEEQYLGLAL VDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYST
Sbjct: 3373 SAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYST 3432

Query: 522  PSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEG 581
            PSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEG
Sbjct: 3433 PSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEG 3492

Query: 582  EDD-NPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHI 640
            E+D NPPCPRL   L++ + PEVLQDSLDR YSTPS   E  DS Q YRS FY  E++ +
Sbjct: 3493 EEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRV 3552

Query: 641  SFALYVD 647
              A+ +D
Sbjct: 3553 GLAVDMD 3559


>gi|239741309 PREDICTED: hypothetical protein XP_002344485 [Homo
           sapiens]
          Length = 4621

 Score = 1204 bits (3115), Expect = 0.0
 Identities = 601/648 (92%), Positives = 618/648 (95%), Gaps = 1/648 (0%)

Query: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
           MVVSAGPLSSEKAEMNILEINEKL PQLAEKKQQFRNLKE+CF+TQLAGFLAN+QKKYKY
Sbjct: 272 MVVSAGPLSSEKAEMNILEINEKLHPQLAEKKQQFRNLKERCFVTQLAGFLANQQKKYKY 331

Query: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120
           EECKDLIK MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS
Sbjct: 332 EECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 391

Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180
           RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRL QHLVQKLSPENDNDDDEDVQVE+AE
Sbjct: 392 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVELAE 451

Query: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240
           KVQKSSAPREMQKAEEKEVPEDS EECAIT SNSHGPYDSNQPH+KTKITFEEDKVDSTL
Sbjct: 452 KVQKSSAPREMQKAEEKEVPEDSQEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTL 511

Query: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP 300
           IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP
Sbjct: 512 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP 571

Query: 301 PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV 360
           PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEK PEV
Sbjct: 572 PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEV 631

Query: 361 LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSC 420
           LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQR+GLA+DMDEIEKYQEVEEDQDPSC
Sbjct: 632 LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRIGLAVDMDEIEKYQEVEEDQDPSC 691

Query: 421 PRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDR 480
           PRLSRELLDEKEPEVLQDSLDRCYSTPS YLELPDLGQPYSSAVYSLEEQYLGLAL VDR
Sbjct: 692 PRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR 751

Query: 481 IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY 540
            KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY
Sbjct: 752 TKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY 811

Query: 541 ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVE 599
           ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGE+D NPPCPRL   L++ +
Sbjct: 812 ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEK 871

Query: 600 EPEVLQDSLDRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFALYVD 647
            PEVLQDSLDR YSTPS   E  DS Q YRS FY  E++ +  A+ +D
Sbjct: 872 GPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMD 919



 Score =  703 bits (1814), Expect = 0.0
 Identities = 377/528 (71%), Positives = 404/528 (76%), Gaps = 40/528 (7%)

Query: 169  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 4108 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 4167

Query: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 4168 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 4213

Query: 283  EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
             EV Q+S D  YST S   E   S Q Y S+F++LEE+ V  ++D+G             
Sbjct: 4214 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 4273

Query: 330  ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
                  R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 4274 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 4333

Query: 384  PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
            PYRSAFYVLEQQRVGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 4334 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 4393

Query: 444  YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELL 503
            YSTPS YLELPDLGQPYSSAVYSLEEQYLGLAL VDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 4394 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 4453

Query: 504  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 4454 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 4513

Query: 564  KRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQP 622
            KRRGRRSKKKRRRGRKEGE+D NPPCPRL GVLMEVEEPEVLQDSLD CYSTPSMYFE P
Sbjct: 4514 KRRGRRSKKKRRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELP 4573

Query: 623  DSFQHYRSVFYSFEEEHISFALYVDNRFFTLTVTSLHLVFQMGVIFPQ 670
            DSFQHYRSVFYSFEE+HISFALYVDNRFFTLTVTSLHLVFQMGVIFPQ
Sbjct: 4574 DSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMGVIFPQ 4621



 Score =  608 bits (1569), Expect = e-174
 Identities = 333/505 (65%), Positives = 366/505 (72%), Gaps = 40/505 (7%)

Query: 169  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 2381 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2440

Query: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 2441 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 2486

Query: 283  EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
             EV Q+S D  YST S   E   S Q Y S+F++LEE+ V  ++D+G             
Sbjct: 2487 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 2546

Query: 330  ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
                  R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTPSGCLELTDSCQ
Sbjct: 2547 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQ 2606

Query: 384  PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
            PYRSAFYVLEQQRVGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 2607 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2666

Query: 444  YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELL 503
            YSTPS YLELPDLGQPYSSAVYSLEEQYLGLAL VDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 2667 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 2726

Query: 504  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 2727 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 2786

Query: 564  KRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQP 622
            KRRGRRSKK+RRRGRKEGE+D NPPCPRL   L++ +EPEVLQDSLDRCYSTPS Y E P
Sbjct: 2787 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELP 2846

Query: 623  DSFQHYRSVFYSFEEEHISFALYVD 647
            D  Q Y S  YS EE+++  AL VD
Sbjct: 2847 DLGQPYSSAVYSLEEQYLGLALDVD 2871



 Score =  605 bits (1559), Expect = e-173
 Identities = 330/505 (65%), Positives = 365/505 (72%), Gaps = 40/505 (7%)

Query: 169  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 3376 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 3435

Query: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 3436 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 3481

Query: 283  EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
             EV Q+S D  YST S   E   S Q Y S+F++LEE+ V  ++D+G             
Sbjct: 3482 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 3541

Query: 330  ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
                  R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 3542 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 3601

Query: 384  PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
            PYRSAFYVLEQQRVGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 3602 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 3661

Query: 444  YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELL 503
            YSTPS YLELPDLGQPYSSAVYSLEEQYLGLAL VDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 3662 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 3721

Query: 504  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 3722 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 3781

Query: 564  KRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQP 622
            KRRGRRSKK+RRRGRKEGE+D NPPCPRL   L++ + PEVLQDSLDRCYSTPS   E  
Sbjct: 3782 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 3841

Query: 623  DSFQHYRSVFYSFEEEHISFALYVD 647
            DS Q YRS FY  E++ +  A+ +D
Sbjct: 3842 DSCQPYRSAFYVLEQQRVGLAVDMD 3866



 Score =  604 bits (1558), Expect = e-173
 Identities = 330/505 (65%), Positives = 365/505 (72%), Gaps = 40/505 (7%)

Query: 169  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 3864 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 3923

Query: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 3924 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 3969

Query: 283  EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
             EV Q+S D  YST S   E   S Q Y S+F++LEE+ V  ++D+G             
Sbjct: 3970 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 4029

Query: 330  ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
                  R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 4030 RRSKKERRRGRKEGEEDQTPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 4089

Query: 384  PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
            PYRSAFYVLEQQRVGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 4090 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 4149

Query: 444  YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELL 503
            YSTPS YLELPDLGQPYSSAVYSLEEQYLGLAL VDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 4150 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 4209

Query: 504  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 4210 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 4269

Query: 564  KRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQP 622
            KRRGRRSKK+RRRGRKEGE+D NPPCPRL   L++ + PEVLQDSLDRCYSTPS   E  
Sbjct: 4270 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 4329

Query: 623  DSFQHYRSVFYSFEEEHISFALYVD 647
            DS Q YRS FY  E++ +  A+ +D
Sbjct: 4330 DSCQPYRSAFYVLEQQRVGLAVDMD 4354



 Score =  602 bits (1553), Expect = e-172
 Identities = 329/505 (65%), Positives = 364/505 (72%), Gaps = 40/505 (7%)

Query: 169  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 3620 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 3679

Query: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 3680 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 3725

Query: 283  EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
             EV Q+S D  YST S   E   S Q Y S+F++LEE+ V  ++D+G             
Sbjct: 3726 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 3785

Query: 330  ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
                  R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 3786 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 3845

Query: 384  PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
            PYRSAFYVLEQQRVGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 3846 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 3905

Query: 444  YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELL 503
            YSTPS YLELPDLGQPYSSAVYSLEEQYLGLAL VDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 3906 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 3965

Query: 504  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 3966 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 4025

Query: 564  KRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQP 622
            KRRGRRSKK+RRRGRKEGE+D  PPCPRL   L++ + PEVLQDSLDRCYSTPS   E  
Sbjct: 4026 KRRGRRSKKERRRGRKEGEEDQTPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 4085

Query: 623  DSFQHYRSVFYSFEEEHISFALYVD 647
            DS Q YRS FY  E++ +  A+ +D
Sbjct: 4086 DSCQPYRSAFYVLEQQRVGLAVDMD 4110



 Score =  601 bits (1549), Expect = e-172
 Identities = 329/505 (65%), Positives = 364/505 (72%), Gaps = 40/505 (7%)

Query: 169  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 673  DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 732

Query: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 733  SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 778

Query: 283  EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
             EV Q+S D  YST S   E   S Q Y S+F++LEE+ V  ++D+G             
Sbjct: 779  PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 838

Query: 330  ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
                  R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTPSGCLELTDSCQ
Sbjct: 839  RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQ 898

Query: 384  PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
            PYRSAFYVLEQQRVGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 899  PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 958

Query: 444  YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELL 503
            YSTPS YLELPDLGQPYSSAVYSLEEQYLGLAL VDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 959  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 1018

Query: 504  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 1019 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 1078

Query: 564  KRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQP 622
            KRRGRRSKK+RRRGRKEGE+D NPPCPRL   L++ + PEVLQDSLDRCYSTPS   E  
Sbjct: 1079 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 1138

Query: 623  DSFQHYRSVFYSFEEEHISFALYVD 647
            DS Q YRS FY  E++ +  A+ +D
Sbjct: 1139 DSCQPYRSAFYVLEQQRVGLAVDMD 1163



 Score =  601 bits (1549), Expect = e-172
 Identities = 329/505 (65%), Positives = 364/505 (72%), Gaps = 40/505 (7%)

Query: 169  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 917  DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 976

Query: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 977  SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 1022

Query: 283  EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
             EV Q+S D  YST S   E   S Q Y S+F++LEE+ V  ++D+G             
Sbjct: 1023 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 1082

Query: 330  ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
                  R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 1083 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1142

Query: 384  PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
            PYRSAFYVLEQQRVGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 1143 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 1202

Query: 444  YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELL 503
            YSTPS YLELPDLGQPYSSAVYSLEEQYLGLAL VDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 1203 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 1262

Query: 504  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 1263 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 1322

Query: 564  KRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQP 622
            KRRGRRSKK+RRRGRKEGE+D NPPCPRL   L++ + PEVLQDSLDR YSTPS   E  
Sbjct: 1323 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELT 1382

Query: 623  DSFQHYRSVFYSFEEEHISFALYVD 647
            DS Q YRS FY  E++ +  A+ +D
Sbjct: 1383 DSCQPYRSAFYVLEQQRVGLAVDMD 1407



 Score =  601 bits (1549), Expect = e-172
 Identities = 329/505 (65%), Positives = 364/505 (72%), Gaps = 40/505 (7%)

Query: 169  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 1161 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1220

Query: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 1221 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 1266

Query: 283  EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
             EV Q+S D  YST S   E   S Q Y S+F++LEE+ V  ++D+G             
Sbjct: 1267 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 1326

Query: 330  ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
                  R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTPSGCLELTDSCQ
Sbjct: 1327 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQ 1386

Query: 384  PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
            PYRSAFYVLEQQRVGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 1387 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 1446

Query: 444  YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELL 503
            YSTPS YLELPDLGQPYSSAVYSLEEQYLGLAL VDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 1447 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 1506

Query: 504  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 1507 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 1566

Query: 564  KRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQP 622
            KRRGRRSKK+RRRGRKEGE+D NPPCPRL   L++ + PEVLQDSLDRCYSTPS   E  
Sbjct: 1567 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 1626

Query: 623  DSFQHYRSVFYSFEEEHISFALYVD 647
            DS Q YRS FY  E++ +  A+ +D
Sbjct: 1627 DSCQPYRSAFYVLEQQRVGLAVDMD 1651



 Score =  601 bits (1549), Expect = e-172
 Identities = 329/505 (65%), Positives = 364/505 (72%), Gaps = 40/505 (7%)

Query: 169  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 1405 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1464

Query: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 1465 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 1510

Query: 283  EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
             EV Q+S D  YST S   E   S Q Y S+F++LEE+ V  ++D+G             
Sbjct: 1511 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 1570

Query: 330  ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
                  R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 1571 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1630

Query: 384  PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
            PYRSAFYVLEQQRVGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 1631 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 1690

Query: 444  YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELL 503
            YSTPS YLELPDLGQPYSSAVYSLEEQYLGLAL VDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 1691 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 1750

Query: 504  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 1751 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 1810

Query: 564  KRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQP 622
            KRRGRRSKK+RRRGRKEGE+D NPPCPRL   L++ + PEVLQDSLDR YSTPS   E  
Sbjct: 1811 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELT 1870

Query: 623  DSFQHYRSVFYSFEEEHISFALYVD 647
            DS Q YRS FY  E++ +  A+ +D
Sbjct: 1871 DSCQPYRSAFYVLEQQRVGLAVDMD 1895



 Score =  600 bits (1547), Expect = e-171
 Identities = 323/482 (67%), Positives = 355/482 (73%), Gaps = 37/482 (7%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVE 248
            RE+   +E EV +DSL+ C  T S      D  QP+     + EE  +   L        
Sbjct: 3155 RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD------- 3207

Query: 249  WEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPEMLA 305
                   +   + D EEEE++GP  PR    L E  E EV Q+S D  YST S   E   
Sbjct: 3208 -------VDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPD 3260

Query: 306  SYQSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVKKEDQEATGP 346
            S Q Y S+F++LEE+ V  ++D+G                   R R  +  +EDQ    P
Sbjct: 3261 SCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCP 3320

Query: 347  RLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEI 406
            RLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLA+DMDEI
Sbjct: 3321 RLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEI 3380

Query: 407  EKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYS 466
            EKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPS YLELPDLGQPYSSAVYS
Sbjct: 3381 EKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYS 3440

Query: 467  LEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 526
            LEEQYLGLAL VDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL
Sbjct: 3441 LEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 3500

Query: 527  EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDD-N 585
            EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGE+D N
Sbjct: 3501 EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN 3560

Query: 586  PPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFALY 645
            PPCPRL   L++ + PEVLQDSLDRCYSTPS   E  DS Q YRS FY  E++ +  A+ 
Sbjct: 3561 PPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVD 3620

Query: 646  VD 647
            +D
Sbjct: 3621 MD 3622



 Score =  597 bits (1539), Expect = e-170
 Identities = 328/505 (64%), Positives = 363/505 (71%), Gaps = 40/505 (7%)

Query: 169  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 1649 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1708

Query: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 1709 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 1754

Query: 283  EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
             EV Q+S D  YST S   E   S Q Y S+F++LEE+ V  ++D+G             
Sbjct: 1755 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 1814

Query: 330  ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
                  R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTPSGCLELTDSCQ
Sbjct: 1815 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQ 1874

Query: 384  PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
            PYRSAFYVLEQQRVGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 1875 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 1934

Query: 444  YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELL 503
            YSTPS YLELPDLGQPYSSAVYSLEEQYLGLAL VDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 1935 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 1994

Query: 504  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 1995 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 2054

Query: 564  KRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQP 622
            KRRGRRSKK+RRRGRKEGE+D NPPCPRL   L++ + PEVLQDSLDR YSTPS   E  
Sbjct: 2055 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELT 2114

Query: 623  DSFQHYRSVFYSFEEEHISFALYVD 647
            DS Q YRS FY  E++ +  A+ +D
Sbjct: 2115 DSCQPYRSAFYVLEQQRVGLAVDMD 2139



 Score =  597 bits (1539), Expect = e-170
 Identities = 328/505 (64%), Positives = 363/505 (71%), Gaps = 40/505 (7%)

Query: 169  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 1893 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1952

Query: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 1953 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 1998

Query: 283  EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
             EV Q+S D  YST S   E   S Q Y S+F++LEE+ V  ++D+G             
Sbjct: 1999 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 2058

Query: 330  ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
                  R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTPSGCLELTDSCQ
Sbjct: 2059 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQ 2118

Query: 384  PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
            PYRSAFYVLEQQRVGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 2119 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2178

Query: 444  YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELL 503
            YSTPS YLELPDLGQPYSSAVYSLEEQYLGLAL VDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 2179 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 2238

Query: 504  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 2239 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 2298

Query: 564  KRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQP 622
            KRRGRRSKK+RRRGRKEGE+D NPPCPRL   L++ + PEVLQDSLDR YSTPS   E  
Sbjct: 2299 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELT 2358

Query: 623  DSFQHYRSVFYSFEEEHISFALYVD 647
            DS Q YRS FY  E++ +  A+ +D
Sbjct: 2359 DSCQPYRSAFYVLEQQRVGLAVDMD 2383



 Score =  597 bits (1539), Expect = e-170
 Identities = 328/505 (64%), Positives = 363/505 (71%), Gaps = 40/505 (7%)

Query: 169  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 2137 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2196

Query: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 2197 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLSRELLEVVE 2242

Query: 283  EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329
             EV Q+S D  YST S   E   S Q Y S+F++LEE+ V  ++D+G             
Sbjct: 2243 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 2302

Query: 330  ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
                  R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTPSGCLELTDSCQ
Sbjct: 2303 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQ 2362

Query: 384  PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443
            PYRSAFYVLEQQRVGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 2363 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2422

Query: 444  YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELL 503
            YSTPS YLELPDLGQPYSSAVYSLEEQYLGLAL VDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 2423 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 2482

Query: 504  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 2483 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 2542

Query: 564  KRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQP 622
            KRRGRRSKK+RRRGRKEGE+D NPPCPRL   L++ + PEVLQDSLDR YSTPS   E  
Sbjct: 2543 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELT 2602

Query: 623  DSFQHYRSVFYSFEEEHISFALYVD 647
            DS Q YRS FY  E++ +  A+ +D
Sbjct: 2603 DSCQPYRSAFYVLEQQRVGLAVDMD 2627



 Score =  559 bits (1440), Expect = e-159
 Identities = 306/487 (62%), Positives = 350/487 (71%), Gaps = 28/487 (5%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVE 248
            RE+ +  E EV +DSL+ C  T S+     DS QP+  +    EE  V  +L       +
Sbjct: 2723 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKK 2782

Query: 249  WEDAVHIIPENESD-----DEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIP 300
             +        ++ +      E EE++ P  PR    L + +E EV Q+S D  YST S  
Sbjct: 2783 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGY 2842

Query: 301  PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV 360
             E+    Q YSS  +SLEEQ + +A+D+ R + DQ ++EDQ    PRLSRELL+  EPEV
Sbjct: 2843 LELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEV 2902

Query: 361  LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKY----------- 409
            LQDSLDRCYSTPS CLE  DSCQPY S+FY LE++ VG ++D+ EIEK            
Sbjct: 2903 LQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRS 2962

Query: 410  --------QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYS 461
                    +E EEDQ+P CPRLSRELLDEKEPEVLQDSLDRCYSTPS YLELPDLGQPYS
Sbjct: 2963 KKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 3022

Query: 462  SAVYSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYST 521
            SAVYSLEEQYLGLAL VDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYST
Sbjct: 3023 SAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYST 3082

Query: 522  PSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEG 581
            PSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEG
Sbjct: 3083 PSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEG 3142

Query: 582  EDD-NPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHI 640
            E+D NPPCPRL   L++ +EPEVLQDSLDRCYSTPS Y E PD  Q Y S  YS EE+++
Sbjct: 3143 EEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYL 3202

Query: 641  SFALYVD 647
              AL VD
Sbjct: 3203 GLALDVD 3209



 Score =  556 bits (1432), Expect = e-158
 Identities = 304/482 (63%), Positives = 345/482 (71%), Gaps = 37/482 (7%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVE 248
            RE+   +  EV +DSL+    T S      DS QP++      E+ +V   +        
Sbjct: 2573 RELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVD------- 2625

Query: 249  WEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPEMLA 305
                   + E E   E EE++ P  PR    L + +E EV Q+S D  YST S   E+  
Sbjct: 2626 -------MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPD 2678

Query: 306  SYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSL 365
              Q YSS  +SLEEQ + +A+D+ R + DQ ++EDQ    PRLSRELL+  EPEVLQDSL
Sbjct: 2679 LGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSL 2738

Query: 366  DRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKY---------------- 409
            DRCYSTPS CLE  DSCQPY S+FY LE++ VG ++D+ EIEK                 
Sbjct: 2739 DRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERR 2798

Query: 410  ---QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYS 466
               +E EEDQ+P CPRLSRELLDEKEPEVLQDSLDRCYSTPS YLELPDLGQPYSSAVYS
Sbjct: 2799 RGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYS 2858

Query: 467  LEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 526
            LEEQYLGLAL VDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL
Sbjct: 2859 LEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 2918

Query: 527  EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDD-N 585
            EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGE+D N
Sbjct: 2919 EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN 2978

Query: 586  PPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFALY 645
            PPCPRL   L++ +EPEVLQDSLDRCYSTPS Y E PD  Q Y S  YS EE+++  AL 
Sbjct: 2979 PPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD 3038

Query: 646  VD 647
            VD
Sbjct: 3039 VD 3040



 Score =  551 bits (1420), Expect = e-157
 Identities = 302/487 (62%), Positives = 348/487 (71%), Gaps = 28/487 (5%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVE 248
            RE+ +  E EV +DSL+ C  T S+     DS QP+  +    EE  V  +L       +
Sbjct: 2892 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKK 2951

Query: 249  WEDAVHIIPENESD-----DEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIP 300
             +        ++ +      E EE++ P  PR    L + +E EV Q+S D  YST S  
Sbjct: 2952 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGY 3011

Query: 301  PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV 360
             E+    Q YSS  +SLEEQ + +A+D+ R + DQ ++EDQ    PRLSRELL+  EPEV
Sbjct: 3012 LELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEV 3071

Query: 361  LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKY----------- 409
            LQDSLDRCYSTPS CLE  DSCQPY S+FY LE++ VG ++D+ EIEK            
Sbjct: 3072 LQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRS 3131

Query: 410  --------QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYS 461
                    +E EEDQ+P CPRLSRELLDEKEPEVLQDSLDRCYSTPS YLELPDLGQPYS
Sbjct: 3132 KKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 3191

Query: 462  SAVYSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYST 521
            SAVYSLEEQYLGLAL VDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYST
Sbjct: 3192 SAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYST 3251

Query: 522  PSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEG 581
            PSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEG
Sbjct: 3252 PSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEG 3311

Query: 582  EDD-NPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHI 640
            E+D NPPCPRL   L++ + PEVLQDSLDRCYSTPS   E  DS Q YRS FY  E++ +
Sbjct: 3312 EEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRV 3371

Query: 641  SFALYVD 647
              A+ +D
Sbjct: 3372 GLAVDMD 3378



 Score =  541 bits (1395), Expect = e-154
 Identities = 347/711 (48%), Positives = 419/711 (58%), Gaps = 100/711 (14%)

Query: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
           MVVSAGP SSEKAEMNILEINEKLRPQLAE KQQF NLKE+CF+TQLAGFLAN+QKKY Y
Sbjct: 1   MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFVTQLAGFLANQQKKYNY 60

Query: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120
           EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVH+QERELTQLREKLREGRDAS
Sbjct: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120

Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180
           RSLNEHLQALLT DEPDKSQGQDLQEQLAEGCRL QHLVQKLSPEND D+DEDVQVE AE
Sbjct: 121 RSLNEHLQALLTLDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE 180

Query: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240
           KVQKSSAPRE+QK EE +VPEDSLEECAITCSNSHGP DSNQPHK  KITFEED+V+STL
Sbjct: 181 KVQKSSAPREVQKTEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240

Query: 241 I--GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLS 298
           +    SSH E +DA++I+P            GP S            P  S     + L 
Sbjct: 241 VVDRESSHDECQDALNILP----------VPGPTSSATNVSMVVSAGPLSSEKAEMNILE 290

Query: 299 IPPEMLASYQSYSSTFHSLEEQQVCMAVDIG--------RHRWDQVK------------- 337
           I  ++          F +L+E+  C    +         ++++++ K             
Sbjct: 291 INEKLHPQLAEKKQQFRNLKER--CFVTQLAGFLANQQKKYKYEECKDLIKSMLRNERQF 348

Query: 338 KEDQEATGPRLSREL--------LDEKE----PEVLQDSLDRCYSTPSGCLELTDSCQPY 385
           KE++ A   + + EL          E+E     E L++  D   S       L    +P 
Sbjct: 349 KEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPD 408

Query: 386 RSAFYVLEQQRV-GLAI--------------DMDEIEKYQEVEEDQDPSCPRLSRELLDE 430
           +S    L++Q   G  +              D DE  + +  E+ Q  S P   RE+   
Sbjct: 409 KSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVELAEKVQKSSAP---REMQKA 465

Query: 431 KEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLAL-------------- 476
           +E EV +DS + C  T S+     D  QP+     + EE  +   L              
Sbjct: 466 EEKEVPEDSQEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVH 525

Query: 477 AVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 536
            +   + D EEEE++GP  P   R L E  E EV Q+S D  YST S   E   S Q Y 
Sbjct: 526 IIPENESDDEEEEEKGPVSP---RNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYS 582

Query: 537 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDDNPPCPRLYGVLM 596
           S+F++LEE+ V  ++D+G                  + R  + + ED     PRL   L+
Sbjct: 583 STFHSLEEQQVCMAVDIG------------------RHRWDQVKKEDQEATGPRLSRELL 624

Query: 597 EVEEPEVLQDSLDRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFALYVD 647
           + + PEVLQDSLDRCYSTPS   E  DS Q YRS FY  E++ I  A+ +D
Sbjct: 625 DEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRIGLAVDMD 675


>gi|7657017 hypothetical protein LOC25832 [Homo sapiens]
          Length = 921

 Score = 1084 bits (2803), Expect = 0.0
 Identities = 539/579 (93%), Positives = 553/579 (95%), Gaps = 1/579 (0%)

Query: 70  MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 129
           MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA
Sbjct: 1   MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 60

Query: 130 LLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR 189
           LLTPDEPDKSQGQDLQEQLAEGCRL QHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR
Sbjct: 61  LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR 120

Query: 190 EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVEW 249
           EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPH+KTKITFEEDKVDSTLIGSSSHVEW
Sbjct: 121 EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEW 180

Query: 250 EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQS 309
           EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASY+S
Sbjct: 181 EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYKS 240

Query: 310 YSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCY 369
           YSSTFHSLEEQQVCMAVDIGRHRWDQVKKED EATGPRLSRELLDEK PEVLQDSLDRCY
Sbjct: 241 YSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCY 300

Query: 370 STPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLD 429
           STPSGCLELTDSCQPYRSAFYVLEQQRVGLA++MDEIEKYQEVEEDQDPSCPRLSRELLD
Sbjct: 301 STPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLD 360

Query: 430 EKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEE 489
           EKEPEVLQDSL RCYSTPS YLELPDLGQPYSSAVYSLEEQYLGLAL VDRIKKDQEEEE
Sbjct: 361 EKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE 420

Query: 490 DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF 549
           DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF
Sbjct: 421 DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF 480

Query: 550 SLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVEEPEVLQDSL 608
           SLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGE+D NPPCPRL   L++ + PEVLQDSL
Sbjct: 481 SLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSL 540

Query: 609 DRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFALYVD 647
           DRCYSTPS   E  DS Q YRS FY  E++ +  A+ +D
Sbjct: 541 DRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMD 579



 Score =  690 bits (1781), Expect = 0.0
 Identities = 384/602 (63%), Positives = 437/602 (72%), Gaps = 36/602 (5%)

Query: 90  EELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPD---------EPDKSQ 140
           +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP          +P  S 
Sbjct: 335 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSA 394

Query: 141 GQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR---EMQKAEEK 197
              L+EQ   G  L    ++K     D +++ED         Q    PR   E+ +  E 
Sbjct: 395 VYSLEEQYL-GLALDVDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEP 439

Query: 198 EVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIP 257
           EV +DSL+ C  T S+     DS QP+  +    EE  V  +L       + +       
Sbjct: 440 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGR 499

Query: 258 ENESD-----DEEEEEKGPVSPRNLQESEEE---EVPQESWDEGYSTLSIPPEMLASYQS 309
            ++ +      E EE++ P  PR  +E  +E   EV Q+S D  YST S   E+  S Q 
Sbjct: 500 RSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQP 559

Query: 310 YSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCY 369
           Y S F+ LE+Q+V +AVD+      Q  +EDQ+ + PRLS ELLDEKEPEVLQ+SLDRCY
Sbjct: 560 YRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQESLDRCY 619

Query: 370 STPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLD 429
           STPSGCLELTDSCQPYRSAFY+LEQQRVGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLD
Sbjct: 620 STPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLD 679

Query: 430 EKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEE 489
           EKEPEVLQDSL RCYSTPS YLELPDLGQPYSSAVYSLEEQYLGLAL VDRIKKDQEEEE
Sbjct: 680 EKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE 739

Query: 490 DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF 549
           DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF
Sbjct: 740 DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF 799

Query: 550 SLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVEEPEVLQDSL 608
           SLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGE+D NPPCPRL  +LMEVEEPEVLQDSL
Sbjct: 800 SLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSMLMEVEEPEVLQDSL 859

Query: 609 DRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFALYVDNRFFTLTVTSLHLVFQMGVIF 668
           D CYSTPSMYFE PDSFQHYRSVFYSFEEEHISFALYVDNRFFTLTVTSLHLVFQMGVIF
Sbjct: 860 DICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFALYVDNRFFTLTVTSLHLVFQMGVIF 919

Query: 669 PQ 670
           PQ
Sbjct: 920 PQ 921


>gi|156071420 hypothetical protein LOC728912 [Homo sapiens]
          Length = 790

 Score =  995 bits (2572), Expect = 0.0
 Identities = 505/582 (86%), Positives = 527/582 (90%), Gaps = 1/582 (0%)

Query: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
           MVVSAGPLSSEKAEMNILEINEKL PQLAEKKQQFR+LKEKCF+TQ+A FLA +Q KYKY
Sbjct: 197 MVVSAGPLSSEKAEMNILEINEKLCPQLAEKKQQFRSLKEKCFVTQVACFLAKQQNKYKY 256

Query: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120
           EECKDLIK MLRNERQFKEEKLAEQLKQAEELRQYKVLVH+QERELTQLREKLREGRDAS
Sbjct: 257 EECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 316

Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180
           RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRL QHLVQKLSPENDNDDDEDVQVEVAE
Sbjct: 317 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE 376

Query: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240
           KVQKSS+PREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPH+KTKITFEEDKVDSTL
Sbjct: 377 KVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 436

Query: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP 300
           IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP
Sbjct: 437 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP 496

Query: 301 PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV 360
           PE LASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV
Sbjct: 497 PERLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV 556

Query: 361 LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSC 420
           LQDSLDRCYSTPS  L LTDSCQPYRSAFYVLEQQR+GLA+DMDEIEKYQEVEEDQDPSC
Sbjct: 557 LQDSLDRCYSTPSVYLGLTDSCQPYRSAFYVLEQQRIGLAVDMDEIEKYQEVEEDQDPSC 616

Query: 421 PRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDR 480
           PRLSRELL EKEPEVLQDSLDRCYSTPS YLELPDLGQPY SAVYSLEEQYLGLAL VDR
Sbjct: 617 PRLSRELLAEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYRSAVYSLEEQYLGLALDVDR 676

Query: 481 IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY 540
           IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD     P   L       P    F 
Sbjct: 677 IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDVIQLLP-VVLNSLTPASPTEVPFM 735

Query: 541 ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGE 582
              +  + F L   +++++G+G+K      ++K     K+G+
Sbjct: 736 HWRKNMLAFLLTWEKLKRRGRGRKEGEEDQRRKEEGEEKKGK 777



 Score =  382 bits (982), Expect = e-106
 Identities = 260/620 (41%), Positives = 336/620 (54%), Gaps = 96/620 (15%)

Query: 90  EELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 149
           +E++QYKVLVH+QERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA
Sbjct: 15  QEIQQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 74

Query: 150 EGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAI 209
           EGCRL QHLVQKLSPEND D+DEDVQVE  EKV +SSAPRE+QKAEE +VPEDSLEECAI
Sbjct: 75  EGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESSAPREVQKAEESKVPEDSLEECAI 134

Query: 210 TCSNSHGPYDSNQPHKKTKITFEEDKVDSTLI--GSSSHVEWEDAVHIIPENESDDEEEE 267
           TCSNSHGP DS QPHK  KITFEEDKV+S+L+    SSH   +DA++I+P          
Sbjct: 135 TCSNSHGPCDSIQPHKNIKITFEEDKVNSSLVVDRESSHDGCQDALNILP---------- 184

Query: 268 EKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEE-----QQV 322
             GP S            P  S     + L I  ++          F SL+E     Q  
Sbjct: 185 VPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLCPQLAEKKQQFRSLKEKCFVTQVA 244

Query: 323 C-MAVDIGRHRWDQVK-------KEDQEATGPRLSRELLDEKE----------------- 357
           C +A    ++++++ K       + +++    +L+ +L   +E                 
Sbjct: 245 CFLAKQQNKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQ 304

Query: 358 -PEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRV-GLAI-------------- 401
             E L++  D   S       L    +P +S    L++Q   G  +              
Sbjct: 305 LREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDN 364

Query: 402 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYS 461
           D DE  + +  E+ Q  S P   RE+   +E EV +DSL+ C  T S+     D  QP+ 
Sbjct: 365 DDDEDVQVEVAEKVQKSSSP---REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 421

Query: 462 SAVYSLEEQYLGLAL--------------AVDRIKKDQEEEEDQGPPCPRLSRELLEVVE 507
               + EE  +   L               +   + D EEEE++GP  P   R L E  E
Sbjct: 422 KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSP---RNLQESEE 478

Query: 508 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 567
            EV Q+S D  YST S   E+  S Q Y S+F++LEE+ V  ++D+G             
Sbjct: 479 EEVPQESWDEGYSTLSIPPERLASYQSYSSTFHSLEEQQVCMAVDIG------------- 525

Query: 568 RRSKKKRRRGRKEGEDDNPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQPDSFQH 627
                + R  + + ED     PRL   L++ +EPEVLQDSLDRCYSTPS+Y    DS Q 
Sbjct: 526 -----RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSVYLGLTDSCQP 580

Query: 628 YRSVFYSFEEEHISFALYVD 647
           YRS FY  E++ I  A+ +D
Sbjct: 581 YRSAFYVLEQQRIGLAVDMD 600



 Score =  221 bits (563), Expect = 2e-57
 Identities = 141/327 (43%), Positives = 185/327 (56%), Gaps = 38/327 (11%)

Query: 335 QVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQ 394
           +V ++ Q+++ PR   E+   +E EV +DSL+ C  T S      DS QP+R      E+
Sbjct: 373 EVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEE 429

Query: 395 QRVGLAID--------------MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL 440
            +V   +               + E E   E EE++ P  PR    L + +E EV Q+S 
Sbjct: 430 DKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESW 486

Query: 441 DRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSR 500
           D  YST S   E     Q YSS  +SLEEQ + +A+ + R + DQ ++EDQ    PRLSR
Sbjct: 487 DEGYSTLSIPPERLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSR 546

Query: 501 ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKG 560
           ELL+  EPEVLQDSLDRCYSTPS  L   DSCQPY S+FY LE++ +G ++D+ EIEK  
Sbjct: 547 ELLDEKEPEVLQDSLDRCYSTPSVYLGLTDSCQPYRSAFYVLEQQRIGLAVDMDEIEKY- 605

Query: 561 KGKKRRGRRSKKKRRRGRKEGEDDNPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFE 620
                            ++  ED +P CPRL   L+  +EPEVLQDSLDRCYSTPS Y E
Sbjct: 606 -----------------QEVEEDQDPSCPRLSRELLAEKEPEVLQDSLDRCYSTPSGYLE 648

Query: 621 QPDSFQHYRSVFYSFEEEHISFALYVD 647
            PD  Q YRS  YS EE+++  AL VD
Sbjct: 649 LPDLGQPYRSAVYSLEEQYLGLALDVD 675



 Score = 39.3 bits (90), Expect = 0.012
 Identities = 48/186 (25%), Positives = 77/186 (41%), Gaps = 21/186 (11%)

Query: 295 STLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLD 354
           ST  +P +     Q Y    HS E +   +   +   R     +   E     L+ +  D
Sbjct: 5   STGRLPGQPTQEIQQYKVLVHSQERELTQLREKLREGR--DASRSLNEHLQALLTPDEPD 62

Query: 355 EKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEE 414
           + + + LQ+ L        GC          R A +++  Q++    D DE E  Q VEE
Sbjct: 63  KSQGQDLQEQL------AEGC----------RLAQHLV--QKLSPENDEDEDEDVQ-VEE 103

Query: 415 DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGL 474
           D+        RE+   +E +V +DSL+ C  T S+     D  QP+ +   + EE  +  
Sbjct: 104 DEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSIQPHKNIKITFEEDKVNS 163

Query: 475 ALAVDR 480
           +L VDR
Sbjct: 164 SLVVDR 169


>gi|119709825 neuroblastoma breakpoint family, member 11-like [Homo
           sapiens]
          Length = 790

 Score =  995 bits (2572), Expect = 0.0
 Identities = 505/582 (86%), Positives = 527/582 (90%), Gaps = 1/582 (0%)

Query: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
           MVVSAGPLSSEKAEMNILEINEKL PQLAEKKQQFR+LKEKCF+TQ+A FLA +Q KYKY
Sbjct: 197 MVVSAGPLSSEKAEMNILEINEKLCPQLAEKKQQFRSLKEKCFVTQVACFLAKQQNKYKY 256

Query: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120
           EECKDLIK MLRNERQFKEEKLAEQLKQAEELRQYKVLVH+QERELTQLREKLREGRDAS
Sbjct: 257 EECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 316

Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180
           RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRL QHLVQKLSPENDNDDDEDVQVEVAE
Sbjct: 317 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE 376

Query: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240
           KVQKSS+PREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPH+KTKITFEEDKVDSTL
Sbjct: 377 KVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 436

Query: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP 300
           IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP
Sbjct: 437 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP 496

Query: 301 PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV 360
           PE LASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV
Sbjct: 497 PERLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV 556

Query: 361 LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSC 420
           LQDSLDRCYSTPS  L LTDSCQPYRSAFYVLEQQR+GLA+DMDEIEKYQEVEEDQDPSC
Sbjct: 557 LQDSLDRCYSTPSVYLGLTDSCQPYRSAFYVLEQQRIGLAVDMDEIEKYQEVEEDQDPSC 616

Query: 421 PRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDR 480
           PRLSRELL EKEPEVLQDSLDRCYSTPS YLELPDLGQPY SAVYSLEEQYLGLAL VDR
Sbjct: 617 PRLSRELLAEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYRSAVYSLEEQYLGLALDVDR 676

Query: 481 IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY 540
           IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD     P   L       P    F 
Sbjct: 677 IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDVIQLLP-VVLNSLTPASPTEVPFM 735

Query: 541 ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGE 582
              +  + F L   +++++G+G+K      ++K     K+G+
Sbjct: 736 HWRKNMLAFLLTWEKLKRRGRGRKEGEEDQRRKEEGEEKKGK 777



 Score =  384 bits (985), Expect = e-106
 Identities = 261/620 (42%), Positives = 336/620 (54%), Gaps = 96/620 (15%)

Query: 90  EELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 149
           EE++QYKVLVH+QERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA
Sbjct: 15  EEIQQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 74

Query: 150 EGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAI 209
           EGCRL QHLVQKLSPEND D+DEDVQVE  EKV +SSAPRE+QKAEE +VPEDSLEECAI
Sbjct: 75  EGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESSAPREVQKAEESKVPEDSLEECAI 134

Query: 210 TCSNSHGPYDSNQPHKKTKITFEEDKVDSTLI--GSSSHVEWEDAVHIIPENESDDEEEE 267
           TCSNSHGP DS QPHK  KITFEEDKV+S+L+    SSH   +DA++I+P          
Sbjct: 135 TCSNSHGPCDSIQPHKNIKITFEEDKVNSSLVVDRESSHDGCQDALNILP---------- 184

Query: 268 EKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEE-----QQV 322
             GP S            P  S     + L I  ++          F SL+E     Q  
Sbjct: 185 VPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLCPQLAEKKQQFRSLKEKCFVTQVA 244

Query: 323 C-MAVDIGRHRWDQVK-------KEDQEATGPRLSRELLDEKE----------------- 357
           C +A    ++++++ K       + +++    +L+ +L   +E                 
Sbjct: 245 CFLAKQQNKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQ 304

Query: 358 -PEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRV-GLAI-------------- 401
             E L++  D   S       L    +P +S    L++Q   G  +              
Sbjct: 305 LREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDN 364

Query: 402 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYS 461
           D DE  + +  E+ Q  S P   RE+   +E EV +DSL+ C  T S+     D  QP+ 
Sbjct: 365 DDDEDVQVEVAEKVQKSSSP---REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 421

Query: 462 SAVYSLEEQYLGLAL--------------AVDRIKKDQEEEEDQGPPCPRLSRELLEVVE 507
               + EE  +   L               +   + D EEEE++GP  P   R L E  E
Sbjct: 422 KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSP---RNLQESEE 478

Query: 508 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 567
            EV Q+S D  YST S   E+  S Q Y S+F++LEE+ V  ++D+G             
Sbjct: 479 EEVPQESWDEGYSTLSIPPERLASYQSYSSTFHSLEEQQVCMAVDIG------------- 525

Query: 568 RRSKKKRRRGRKEGEDDNPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQPDSFQH 627
                + R  + + ED     PRL   L++ +EPEVLQDSLDRCYSTPS+Y    DS Q 
Sbjct: 526 -----RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSVYLGLTDSCQP 580

Query: 628 YRSVFYSFEEEHISFALYVD 647
           YRS FY  E++ I  A+ +D
Sbjct: 581 YRSAFYVLEQQRIGLAVDMD 600



 Score =  221 bits (563), Expect = 2e-57
 Identities = 141/327 (43%), Positives = 185/327 (56%), Gaps = 38/327 (11%)

Query: 335 QVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQ 394
           +V ++ Q+++ PR   E+   +E EV +DSL+ C  T S      DS QP+R      E+
Sbjct: 373 EVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEE 429

Query: 395 QRVGLAID--------------MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL 440
            +V   +               + E E   E EE++ P  PR    L + +E EV Q+S 
Sbjct: 430 DKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESW 486

Query: 441 DRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSR 500
           D  YST S   E     Q YSS  +SLEEQ + +A+ + R + DQ ++EDQ    PRLSR
Sbjct: 487 DEGYSTLSIPPERLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSR 546

Query: 501 ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKG 560
           ELL+  EPEVLQDSLDRCYSTPS  L   DSCQPY S+FY LE++ +G ++D+ EIEK  
Sbjct: 547 ELLDEKEPEVLQDSLDRCYSTPSVYLGLTDSCQPYRSAFYVLEQQRIGLAVDMDEIEKY- 605

Query: 561 KGKKRRGRRSKKKRRRGRKEGEDDNPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFE 620
                            ++  ED +P CPRL   L+  +EPEVLQDSLDRCYSTPS Y E
Sbjct: 606 -----------------QEVEEDQDPSCPRLSRELLAEKEPEVLQDSLDRCYSTPSGYLE 648

Query: 621 QPDSFQHYRSVFYSFEEEHISFALYVD 647
            PD  Q YRS  YS EE+++  AL VD
Sbjct: 649 LPDLGQPYRSAVYSLEEQYLGLALDVD 675



 Score = 39.3 bits (90), Expect = 0.012
 Identities = 48/186 (25%), Positives = 77/186 (41%), Gaps = 21/186 (11%)

Query: 295 STLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLD 354
           ST  +P +     Q Y    HS E +   +   +   R     +   E     L+ +  D
Sbjct: 5   STGRLPGQPTEEIQQYKVLVHSQERELTQLREKLREGR--DASRSLNEHLQALLTPDEPD 62

Query: 355 EKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEE 414
           + + + LQ+ L        GC          R A +++  Q++    D DE E  Q VEE
Sbjct: 63  KSQGQDLQEQL------AEGC----------RLAQHLV--QKLSPENDEDEDEDVQ-VEE 103

Query: 415 DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGL 474
           D+        RE+   +E +V +DSL+ C  T S+     D  QP+ +   + EE  +  
Sbjct: 104 DEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSIQPHKNIKITFEEDKVNS 163

Query: 475 ALAVDR 480
           +L VDR
Sbjct: 164 SLVVDR 169


>gi|14149997 neuroblastoma breakpoint family, member 3 [Homo
           sapiens]
          Length = 633

 Score =  815 bits (2106), Expect = 0.0
 Identities = 418/553 (75%), Positives = 465/553 (84%)

Query: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
           MVVSAGP S EKAEMNILEIN+K RPQLAE KQQFRNLK+KC +TQ+A FLANRQ  Y Y
Sbjct: 57  MVVSAGPWSGEKAEMNILEINKKSRPQLAENKQQFRNLKQKCLVTQVAYFLANRQNNYDY 116

Query: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120
           E+CKDLIK MLR+ER   EEKLAE+L QAEELRQYKVLVH+QERELTQLREKL+EGRDAS
Sbjct: 117 EDCKDLIKSMLRDERLLTEEKLAEELGQAEELRQYKVLVHSQERELTQLREKLQEGRDAS 176

Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180
           RSLN+HLQALLTPDEPD SQG+DL+EQLAEGCRL QHLVQKLSPEND+D+DEDV+VE AE
Sbjct: 177 RSLNQHLQALLTPDEPDNSQGRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDVKVEEAE 236

Query: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240
           KVQ+  APRE+QKAEEKEVPEDSLEECAITCSNSH P +SNQP+  T+ITFEED+VDSTL
Sbjct: 237 KVQELYAPREVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVDSTL 296

Query: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP 300
           I SSSH EW DAV IIPENESD E+EEEKGPVSPRNLQESEEEE PQESWDEG  TLSIP
Sbjct: 297 IDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPRNLQESEEEEAPQESWDEGDWTLSIP 356

Query: 301 PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV 360
           P+M ASYQS  STFHS+EEQQV +A+DIGRH  DQVKKEDQEAT PRLSRELLDEKEPEV
Sbjct: 357 PDMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVKKEDQEATSPRLSRELLDEKEPEV 416

Query: 361 LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSC 420
           LQDSLDR YSTP   LEL D CQPYRS FY L++Q +GLA+D+D ++K QE EEDQ P C
Sbjct: 417 LQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPC 476

Query: 421 PRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDR 480
           PRLSREL +  EPE LQDSLDR YSTP  Y ELPD  QPY S  YSLEE+++G +L VD 
Sbjct: 477 PRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDE 536

Query: 481 IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY 540
           I+K QE EEDQ PPCPRL+  L+E  EPEVLQDSLDRCYST S+  +   S Q Y S+FY
Sbjct: 537 IEKYQEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFY 596

Query: 541 ALEEKHVGFSLDV 553
           + EE+ V  +LDV
Sbjct: 597 SFEEQDVSLALDV 609


>gi|239741297 PREDICTED: neuroblastoma breakpoint family, member 9
           [Homo sapiens]
          Length = 299

 Score =  530 bits (1366), Expect = e-150
 Identities = 267/287 (93%), Positives = 275/287 (95%)

Query: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
           MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFR+LKEKCF+TQLAGFLA +Q KYKY
Sbjct: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKY 60

Query: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120
           EECKDLIK MLRNE QFKEEKLAEQLKQAEELRQYKVLVH+QERELTQLREKLREGRDAS
Sbjct: 61  EECKDLIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120

Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180
           RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRL QHLVQKLSPENDNDDDEDVQVEVAE
Sbjct: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE 180

Query: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240
           KVQKSS+PREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPH+KTKITFEEDKVDSTL
Sbjct: 181 KVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240

Query: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQ 287
           IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR    S E+  P+
Sbjct: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTSVGSSEKGGPR 287



 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 34/112 (30%), Positives = 49/112 (43%), Gaps = 17/112 (15%)

Query: 402 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYS 461
           D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S+     D  QP+ 
Sbjct: 169 DDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 225

Query: 462 SAVYSLEEQYLGLALA--------------VDRIKKDQEEEEDQGPPCPRLS 499
               + EE  +   L               +   + D EEEE++GP  PR S
Sbjct: 226 KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTS 277



 Score = 37.7 bits (86), Expect = 0.035
 Identities = 30/104 (28%), Positives = 47/104 (45%), Gaps = 17/104 (16%)

Query: 335 QVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQ 394
           +V ++ Q+++ PR   E+   +E EV +DSL+ C  T S      DS QP+R      E+
Sbjct: 177 EVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEE 233

Query: 395 QRVGLAI--------------DMDEIEKYQEVEEDQDPSCPRLS 424
            +V   +               + E E   E EE++ P  PR S
Sbjct: 234 DKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTS 277



 Score = 35.0 bits (79), Expect = 0.22
 Identities = 42/163 (25%), Positives = 69/163 (42%), Gaps = 27/163 (16%)

Query: 404 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSA 463
           +E+ +Y+ +   Q+    +L  +L + ++         R  +     L  PD  +P  S 
Sbjct: 90  EELRQYKVLVHSQERELTQLREKLREGRDAS-------RSLNEHLQALLTPD--EPDKSQ 140

Query: 464 VYSLEEQYL-GLALAVDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEP 508
              L+EQ   G  LA   ++K     D +++ED         Q    PR   E+ +  E 
Sbjct: 141 GQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEK 197

Query: 509 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSL 551
           EV +DSL+ C  T S+     DS QP+  +    EE  V  +L
Sbjct: 198 EVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240



 Score = 32.3 bits (72), Expect = 1.5
 Identities = 18/50 (36%), Positives = 26/50 (52%)

Query: 595 LMEVEEPEVLQDSLDRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFAL 644
           + + EE EV +DSL+ C  T S      DS Q +R    +FEE+ +   L
Sbjct: 191 MQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240


>gi|221136844 neuroblastoma breakpoint family, member 6 isoform 1
           [Homo sapiens]
          Length = 667

 Score =  479 bits (1234), Expect = e-135
 Identities = 281/504 (55%), Positives = 349/504 (69%), Gaps = 28/504 (5%)

Query: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGF-LANRQKKYK 59
           MVVSA PLSSE+AEMNILEIN++LR QLAE  QQFR+LKEK  +TQ   + LAN+ KKYK
Sbjct: 1   MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60

Query: 60  YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDA 119
            EE KD+I  +LR+E Q   EKLAE+L+QAEELRQYK LVH+Q +ELTQLREKLREGRDA
Sbjct: 61  CEEYKDIIDSVLRDELQ-SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119

Query: 120 SRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDV--QVE 177
           SR LN+HL+ LLTPD+PDKSQGQDL+EQLAEG RL +HLV KLSPEND D+DED   + E
Sbjct: 120 SRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDE 179

Query: 178 VAEKVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVD 237
             EKVQ+S APRE+QK EEKEVP+DSLEECA+TCSNSH P +SNQPH+ TKITF+E +VD
Sbjct: 180 EVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVD 239

Query: 238 STLIGSSSHV--EWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQES---WDE 292
           S L+  S H   E E+A++I PEN++D EEEE K PV PRN Q  E  E+          
Sbjct: 240 SALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRNRQSLEPGELTNLRDFLISP 299

Query: 293 GYSTLSIP--PEMLASYQSYSSTFHSLEEQQVCMAVDIGRH----RWDQV------KKED 340
             S ++ P   +   SY+    +F +L+EQ+VC A D+ R     +WD+       K+ D
Sbjct: 300 VVSHVANPGHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSD 359

Query: 341 ------QEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQ 394
                 QE   PRLSR  L   + E+ Q+SLD C  TPS   +LT S  PY S  Y  E 
Sbjct: 360 LEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFED 419

Query: 395 QRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELP 454
           ++V LA+ +D+I+K QE  EDQ P CPRLS+EL + KE EV +DS++  Y TPS + ++ 
Sbjct: 420 KQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVS 478

Query: 455 DLGQPYSSAVYSLEEQYLGLALAV 478
           D  QPYSS + SLE+Q    AL V
Sbjct: 479 DCHQPYSSTLSSLEDQLACSALDV 502



 Score =  110 bits (276), Expect = 3e-24
 Identities = 106/351 (30%), Positives = 153/351 (43%), Gaps = 64/351 (18%)

Query: 334 DQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLE 393
           D+  ++ QE+  PR   E+   +E EV QDSL+ C  T S     ++S QP+RS     +
Sbjct: 178 DEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFK 234

Query: 394 QQRVGLAIDMD----------------EIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQ 437
           +  V  A+ ++                E +   E EE + P  PR  + L    EP  L 
Sbjct: 235 EHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRNRQSL----EPGELT 290

Query: 438 DSLDRCYSTPSDYLELP---DLGQPYSSAVYS---LEEQYLGLALAVDRI---------- 481
           +  D   S    ++  P   D    Y     S   L+EQ +  A  V R           
Sbjct: 291 NLRDFLISPVVSHVANPGHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETS 350

Query: 482 ------KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 535
                 + D EE + Q    PRLSR  L V + E+ Q+SLD C  TPS   +   S  PY
Sbjct: 351 LGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPY 410

Query: 536 GSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDDNPPCPRLYGVL 595
            S+ Y+ E+K V  +L                     K ++ ++E ED +PPCPRL   L
Sbjct: 411 WSTLYSFEDKQVSLAL-------------------VDKIKKDQEEIEDQSPPCPRLSQEL 451

Query: 596 MEVEEPEVLQDSLDRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFALYV 646
            EV+E EV +DS++  Y TPS++ +  D  Q Y S   S E++    AL V
Sbjct: 452 PEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 502



 Score = 37.4 bits (85), Expect = 0.045
 Identities = 23/62 (37%), Positives = 33/62 (53%), Gaps = 3/62 (4%)

Query: 587 PCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFALYV 646
           P PR    + + EE EV QDSL+ C  T S      +S Q +RS   +F+E  +  AL V
Sbjct: 188 PAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVDSALVV 244

Query: 647 DN 648
           ++
Sbjct: 245 ES 246


>gi|221218991 neuroblastoma breakpoint family, member 4 [Homo
           sapiens]
          Length = 638

 Score =  476 bits (1225), Expect = e-134
 Identities = 289/547 (52%), Positives = 359/547 (65%), Gaps = 54/547 (9%)

Query: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGF-LANRQKKYK 59
           MVVSA PLSSE+AEMNILEIN++LR QLAE  QQFR+LKEK  +TQ   + LAN+ KKYK
Sbjct: 1   MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60

Query: 60  YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDA 119
            EE KD+I  +LR+E Q   EKLAE+L+QAEELRQYK LVH+Q +ELTQLREKLREGRDA
Sbjct: 61  CEEYKDIIDSVLRDELQ-SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119

Query: 120 SRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDV--QVE 177
           SR LN+HL+ LLTPD+PDKSQGQDL+EQLAEG RL +HLV KLSPEND D+DED   + E
Sbjct: 120 SRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDE 179

Query: 178 VAEKVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVD 237
             EKVQ+S APRE+QK EEKEVP+DSLEECA+TCSNSH P +SNQPH+ TKITF+E +VD
Sbjct: 180 EVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVD 239

Query: 238 STLIGSSSHV--EWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYS 295
           S L+  S H   E E+A++I PEN++D EEEE K PV PR+  +S               
Sbjct: 240 SALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSN-------------- 285

Query: 296 TLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRH----RWDQV------KKED----- 340
                     SY+    +F +L+EQ+VC A D+ R     +WD+       K+ D     
Sbjct: 286 ----------SYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVK 335

Query: 341 -QEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGL 399
            QE   PRLSR  L   + E+ Q+SLD C  TPS   +LT S  PY S  Y  E ++V L
Sbjct: 336 GQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSL 395

Query: 400 AIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQP 459
           A+ +D+I+K QE  EDQ P CPRLS+EL + KE EV +DS++  Y TPS + ++ D  QP
Sbjct: 396 AL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQP 454

Query: 460 YSSAVYSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCY 519
           YSS + SLE+Q   LA +   +    E    QG     LS    EV   +V Q  L+   
Sbjct: 455 YSSTLSSLEDQ---LACSALDVASPTEAACPQGTWSGDLSHHQSEV---QVSQAQLEPST 508

Query: 520 STPSSCL 526
             P SCL
Sbjct: 509 LVP-SCL 514



 Score =  115 bits (287), Expect = 2e-25
 Identities = 100/329 (30%), Positives = 149/329 (45%), Gaps = 49/329 (14%)

Query: 334 DQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLE 393
           D+  ++ QE+  PR   E+   +E EV QDSL+ C  T S     ++S QP+RS     +
Sbjct: 178 DEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFK 234

Query: 394 QQRVGLAIDMD----------------EIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQ 437
           +  V  A+ ++                E +   E EE + P  PR   +    +  EV  
Sbjct: 235 EHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSNSYRHREVSF 294

Query: 438 DSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPR 497
            +LD             D+ + YS+  +  +E  LG        + D EE + Q    PR
Sbjct: 295 LALDE-----QKVCSAQDVARDYSNPKW--DETSLGFL----EKQSDLEEVKGQETVAPR 343

Query: 498 LSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIE 557
           LSR  L V + E+ Q+SLD C  TPS   +   S  PY S+ Y+ E+K V  +L      
Sbjct: 344 LSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLAL------ 397

Query: 558 KKGKGKKRRGRRSKKKRRRGRKEGEDDNPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSM 617
                          K ++ ++E ED +PPCPRL   L EV+E EV +DS++  Y TPS+
Sbjct: 398 -------------VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSV 444

Query: 618 YFEQPDSFQHYRSVFYSFEEEHISFALYV 646
           + +  D  Q Y S   S E++    AL V
Sbjct: 445 HHDVSDCHQPYSSTLSSLEDQLACSALDV 473



 Score = 37.4 bits (85), Expect = 0.045
 Identities = 23/62 (37%), Positives = 33/62 (53%), Gaps = 3/62 (4%)

Query: 587 PCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFALYV 646
           P PR    + + EE EV QDSL+ C  T S      +S Q +RS   +F+E  +  AL V
Sbjct: 188 PAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVDSALVV 244

Query: 647 DN 648
           ++
Sbjct: 245 ES 246


>gi|221136848 neuroblastoma breakpoint family, member 6 isoform 2
           [Homo sapiens]
          Length = 638

 Score =  476 bits (1224), Expect = e-134
 Identities = 276/499 (55%), Positives = 342/499 (68%), Gaps = 47/499 (9%)

Query: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGF-LANRQKKYK 59
           MVVSA PLSSE+AEMNILEIN++LR QLAE  QQFR+LKEK  +TQ   + LAN+ KKYK
Sbjct: 1   MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60

Query: 60  YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDA 119
            EE KD+I  +LR+E Q   EKLAE+L+QAEELRQYK LVH+Q +ELTQLREKLREGRDA
Sbjct: 61  CEEYKDIIDSVLRDELQ-SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119

Query: 120 SRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDV--QVE 177
           SR LN+HL+ LLTPD+PDKSQGQDL+EQLAEG RL +HLV KLSPEND D+DED   + E
Sbjct: 120 SRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDE 179

Query: 178 VAEKVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVD 237
             EKVQ+S APRE+QK EEKEVP+DSLEECA+TCSNSH P +SNQPH+ TKITF+E +VD
Sbjct: 180 EVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVD 239

Query: 238 STLIGSSSHV--EWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYS 295
           S L+  S H   E E+A++I PEN++D EEEE K PV PR+  +S               
Sbjct: 240 SALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSN-------------- 285

Query: 296 TLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRH----RWDQV------KKED----- 340
                     SY+    +F +L+EQ+VC A D+ R     +WD+       K+ D     
Sbjct: 286 ----------SYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVK 335

Query: 341 -QEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGL 399
            QE   PRLSR  L   + E+ Q+SLD C  TPS   +LT S  PY S  Y  E ++V L
Sbjct: 336 GQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSL 395

Query: 400 AIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQP 459
           A+ +D+I+K QE  EDQ P CPRLS+EL + KE EV +DS++  Y TPS + ++ D  QP
Sbjct: 396 AL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQP 454

Query: 460 YSSAVYSLEEQYLGLALAV 478
           YSS + SLE+Q    AL V
Sbjct: 455 YSSTLSSLEDQLACSALDV 473



 Score =  115 bits (287), Expect = 2e-25
 Identities = 100/329 (30%), Positives = 149/329 (45%), Gaps = 49/329 (14%)

Query: 334 DQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLE 393
           D+  ++ QE+  PR   E+   +E EV QDSL+ C  T S     ++S QP+RS     +
Sbjct: 178 DEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFK 234

Query: 394 QQRVGLAIDMD----------------EIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQ 437
           +  V  A+ ++                E +   E EE + P  PR   +    +  EV  
Sbjct: 235 EHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSNSYRHREVSF 294

Query: 438 DSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPR 497
            +LD             D+ + YS+  +  +E  LG        + D EE + Q    PR
Sbjct: 295 LALDE-----QKVCSAQDVARDYSNPKW--DETSLGFL----EKQSDLEEVKGQETVAPR 343

Query: 498 LSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIE 557
           LSR  L V + E+ Q+SLD C  TPS   +   S  PY S+ Y+ E+K V  +L      
Sbjct: 344 LSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLAL------ 397

Query: 558 KKGKGKKRRGRRSKKKRRRGRKEGEDDNPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSM 617
                          K ++ ++E ED +PPCPRL   L EV+E EV +DS++  Y TPS+
Sbjct: 398 -------------VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSV 444

Query: 618 YFEQPDSFQHYRSVFYSFEEEHISFALYV 646
           + +  D  Q Y S   S E++    AL V
Sbjct: 445 HHDVSDCHQPYSSTLSSLEDQLACSALDV 473



 Score = 37.4 bits (85), Expect = 0.045
 Identities = 23/62 (37%), Positives = 33/62 (53%), Gaps = 3/62 (4%)

Query: 587 PCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFALYV 646
           P PR    + + EE EV QDSL+ C  T S      +S Q +RS   +F+E  +  AL V
Sbjct: 188 PAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVDSALVV 244

Query: 647 DN 648
           ++
Sbjct: 245 ES 246


>gi|114158664 hypothetical protein LOC343505 [Homo sapiens]
          Length = 421

 Score =  451 bits (1159), Expect = e-126
 Identities = 244/372 (65%), Positives = 281/372 (75%), Gaps = 11/372 (2%)

Query: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
           MVVSAGP SSEKAEMNILEINEKLRPQLAE KQQFRN+K+K  +TQ+AGFLAN+Q KYKY
Sbjct: 21  MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGFLANQQNKYKY 80

Query: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120
           EECKDLIK MLR E QFKEEKLAEQLKQAEELRQYKVLVH+QEREL QLREKLREGRDAS
Sbjct: 81  EECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDAS 140

Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180
            SLN+HLQALLTPD+ D SQGQD +EQLAEGCRL +HLV KLSPEND D+DE+ + +  +
Sbjct: 141 HSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDENDKTKELD 200

Query: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240
           KVQ+S APRE QKAEEKEVPEDSLEECAIT SNSHGP DSN PHK  KIT EEDKV+S L
Sbjct: 201 KVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSIL 260

Query: 241 I--GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR--------NLQESEEEEVPQESW 290
           +    SS  EW+DA++I+ EN++DDEEEE K PV P+         LQESEE+EV Q+S 
Sbjct: 261 VVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSP 320

Query: 291 DEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSR 350
           +E  +T     ++  SYQ    TF +L EQ+VC A D+        K E+     P    
Sbjct: 321 EERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH-SNSKGEETPLGFPDTKY 379

Query: 351 ELLDEKEPEVLQ 362
              DEK+  + Q
Sbjct: 380 CWKDEKDERMSQ 391



 Score = 63.9 bits (154), Expect = 5e-10
 Identities = 58/209 (27%), Positives = 93/209 (44%), Gaps = 27/209 (12%)

Query: 377 ELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 436
           +L + C+  R   + L  +      D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220

Query: 437 QDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVD----------------R 480
           +DSL+ C  T S+     D   P+ +   + EE  +   L VD                 
Sbjct: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280

Query: 481 IKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 535
            + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340

Query: 536 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 564
             +F AL E+ V  + DV       KG++
Sbjct: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369



 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 47/168 (27%), Positives = 72/168 (42%), Gaps = 6/168 (3%)

Query: 479 DRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSS 538
           D   K +E ++ Q  P PR   E  +  E EV +DSL+ C  T S+     DS  P+ + 
Sbjct: 191 DENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNI 247

Query: 539 FYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDDNPPCPRLY--GV-L 595
               EE  V   L V     + + +       + +     +EG+   PP   L+  G+ L
Sbjct: 248 KITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKL 307

Query: 596 MEVEEPEVLQDSLDRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFA 643
            E EE EVLQDS +   +T     +   S+Q     F +  E+ +  A
Sbjct: 308 QESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSA 355



 Score = 31.2 bits (69), Expect = 3.2
 Identities = 17/52 (32%), Positives = 29/52 (55%)

Query: 597 EVEEPEVLQDSLDRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFALYVDN 648
           + EE EV +DSL+ C  T S      DS   ++++  + EE+ ++  L VD+
Sbjct: 213 KAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDS 264


>gi|239758011 PREDICTED: hypothetical protein LOC728841, partial
           [Homo sapiens]
          Length = 166

 Score =  224 bits (571), Expect = 2e-58
 Identities = 111/144 (77%), Positives = 122/144 (84%), Gaps = 1/144 (0%)

Query: 526 LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDD- 584
           LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGE+D 
Sbjct: 1   LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 585 NPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFAL 644
           NPPCPRL   L++ +EPEVLQDSLDRCYSTPS Y E PD  Q Y S  YS EE+++  AL
Sbjct: 61  NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 645 YVDNRFFTLTVTSLHLVFQMGVIF 668
            VD+ + T+ V SLHLVFQ+GVIF
Sbjct: 121 DVDSEYLTMKVISLHLVFQIGVIF 144



 Score =  161 bits (407), Expect = 2e-39
 Identities = 84/123 (68%), Positives = 92/123 (74%), Gaps = 19/123 (15%)

Query: 376 LELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKY-------------------QEVEEDQ 416
           LE  DSCQPY S+FY LE++ VG ++D+ EIEK                    +E EEDQ
Sbjct: 1   LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 417 DPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLAL 476
           +P CPRLSRELLDEKEPEVLQDSLDRCYSTPS YLELPDLGQPYSSAVYSLEEQYLGLAL
Sbjct: 61  NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 477 AVD 479
            VD
Sbjct: 121 DVD 123



 Score =  125 bits (313), Expect = 2e-28
 Identities = 66/122 (54%), Positives = 81/122 (66%), Gaps = 19/122 (15%)

Query: 451 LELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKD-------------------QEEEEDQ 491
           LE PD  QPY S+ Y+LEE+++G +L V  I+K                    +E EEDQ
Sbjct: 1   LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 492 GPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSL 551
            PPCPRLSRELL+  EPEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE+++G +L
Sbjct: 61  NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 552 DV 553
           DV
Sbjct: 121 DV 122



 Score =  112 bits (281), Expect = 8e-25
 Identities = 63/118 (53%), Positives = 76/118 (64%), Gaps = 19/118 (16%)

Query: 306 SYQSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVKKEDQEATGP 346
           S Q Y S+F++LEE+ V  ++D+G                   R R  +  +EDQ    P
Sbjct: 6   SCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQNPPCP 65

Query: 347 RLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMD 404
           RLSRELLDEKEPEVLQDSLDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D
Sbjct: 66  RLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD 123



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 29/68 (42%), Positives = 40/68 (58%), Gaps = 3/68 (4%)

Query: 264 EEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQ 320
           E EE++ P  PR    L + +E EV Q+S D  YST S   E+    Q YSS  +SLEEQ
Sbjct: 55  EGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQ 114

Query: 321 QVCMAVDI 328
            + +A+D+
Sbjct: 115 YLGLALDV 122


>gi|239747446 PREDICTED: similar to Neuroblastoma breakpoint family
           member 6-like protein [Homo sapiens]
          Length = 298

 Score =  119 bits (298), Expect = 9e-27
 Identities = 76/190 (40%), Positives = 110/190 (57%), Gaps = 9/190 (4%)

Query: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGF-LANRQKKYK 59
           M VSA      +AEM+ILE N+ LR +L + KQ F++L EK   ++   + L N  +KYK
Sbjct: 1   MAVSATTCFGPRAEMSILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60

Query: 60  YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDA 119
            EECKDLI+ +L  E QF+E +LAE  + A  LR +  L+ AQ  ELT LR+K++EGR  
Sbjct: 61  CEECKDLIESVLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKIQEGRGV 120

Query: 120 SRSLNEHL-------QALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDN-DDD 171
                +H+       + LL   +    Q Q   EQ+ +G +LT+ LV+KL+ EN N   +
Sbjct: 121 CYLFTQHVKNTVKSFEGLLRNTDIAYYQRQRFCEQMVQGSQLTEILVRKLATENHNGKKN 180

Query: 172 EDVQVEVAEK 181
           ED Q  +A +
Sbjct: 181 EDRQKPLAPR 190


>gi|239741304 PREDICTED: similar to Neuroblastoma breakpoint family
           member 6-like protein [Homo sapiens]
          Length = 298

 Score =  116 bits (291), Expect = 6e-26
 Identities = 75/190 (39%), Positives = 109/190 (57%), Gaps = 9/190 (4%)

Query: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGF-LANRQKKYK 59
           M VSA      +AE++ILE N+ LR +L + KQ F++L EK   ++   + L N  +KYK
Sbjct: 1   MAVSATTCFGPRAEISILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60

Query: 60  YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDA 119
            EECKDLI+ +L  E QF+E +LAE  + A  LR +  L+ AQ  ELT LR+K +EGR  
Sbjct: 61  CEECKDLIESVLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKTQEGRGV 120

Query: 120 SRSLNEHL-------QALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDN-DDD 171
                +H+       + LL   +    Q Q   EQ+ +G +LT+ LV+KL+ EN N   +
Sbjct: 121 CYLFTQHVKNTVKSFEGLLRNTDIAYYQRQRFCEQMVQGSQLTEILVRKLATENHNGKKN 180

Query: 172 EDVQVEVAEK 181
           ED Q  +A +
Sbjct: 181 EDRQKPLAPR 190


>gi|239741281 PREDICTED: Neuroblastoma breakpoint family member
           6-like protein [Homo sapiens]
          Length = 322

 Score =  116 bits (291), Expect = 6e-26
 Identities = 75/190 (39%), Positives = 109/190 (57%), Gaps = 9/190 (4%)

Query: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGF-LANRQKKYK 59
           M VSA      +AE++ILE N+ LR +L + KQ F++L EK   ++   + L N  +KYK
Sbjct: 1   MAVSATTCFGPRAEISILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60

Query: 60  YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDA 119
            EECKDLI+ +L  E QF+E +LAE  + A  LR +  L+ AQ  ELT LR+K +EGR  
Sbjct: 61  CEECKDLIESVLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKTQEGRGV 120

Query: 120 SRSLNEHL-------QALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDN-DDD 171
                +H+       + LL   +    Q Q   EQ+ +G +LT+ LV+KL+ EN N   +
Sbjct: 121 CYLFTQHVKNTVKSFEGLLRNTDIAYYQRQRFCEQMVQGSQLTEILVRKLATENHNGKKN 180

Query: 172 EDVQVEVAEK 181
           ED Q  +A +
Sbjct: 181 EDRQKPLAPR 190


>gi|239752894 PREDICTED: Neuroblastoma breakpoint family member
           6-like protein [Homo sapiens]
          Length = 298

 Score =  114 bits (284), Expect = 4e-25
 Identities = 75/190 (39%), Positives = 107/190 (56%), Gaps = 9/190 (4%)

Query: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGF-LANRQKKYK 59
           M VSA      +AE++ILE N+ LR +L + KQ F++L EK   ++   + L N  +KYK
Sbjct: 1   MAVSATTCFGPRAEISILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60

Query: 60  YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDA 119
            EECKDLI+ +L  E QF+E +LAE  + A  LR +  L+ AQ  ELT LR+K +EGR  
Sbjct: 61  CEECKDLIESVLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKTQEGRGV 120

Query: 120 SRSLNEHL-------QALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDN-DDD 171
                +H+       + LL        Q Q   EQ+ +G +LT+ LV+KL  EN N   +
Sbjct: 121 CYLFTQHVKNTVKSFEGLLRNTGIAYYQRQRFCEQMVQGSQLTEILVRKLVTENHNGKKN 180

Query: 172 EDVQVEVAEK 181
           ED Q  +A +
Sbjct: 181 EDRQKPLAPR 190


>gi|157311604 phosphodiesterase 4D interacting protein isoform 1 [Homo
            sapiens]
          Length = 2346

 Score = 80.5 bits (197), Expect = 5e-15
 Identities = 58/182 (31%), Positives = 97/182 (53%), Gaps = 14/182 (7%)

Query: 79   EEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEH-------LQALL 131
            EEKLAE+L+ A    +Y  L+  Q REL+ LR+K+REGR     +  H        + LL
Sbjct: 1458 EEKLAEELRSASWPGKYDSLIQDQARELSYLRQKIREGRGICYLITRHAKDTVKSFEDLL 1517

Query: 132  TPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVE-VAEKVQKSSAPRE 190
              ++ D   GQ  +EQLA+G +LT+ L  KLS ++   + +   +E +A ++      RE
Sbjct: 1518 RSNDIDYYLGQSFREQLAQGSQLTERLTSKLSTKDHKSEKDQAGLEPLALRLS-----RE 1572

Query: 191  MQKAEEK-EVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVEW 249
            +Q+ E+  EV +  L+  ++T S+SH   DS++    T    +E +  S +   S +  +
Sbjct: 1573 LQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSSTSFLSDELEACSDMDIVSEYTHY 1632

Query: 250  ED 251
            E+
Sbjct: 1633 EE 1634



 Score = 38.1 bits (87), Expect = 0.027
 Identities = 31/85 (36%), Positives = 43/85 (50%), Gaps = 6/85 (7%)

Query: 334  DQVKKEDQEATGP---RLSRELLD-EKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAF 389
            D   ++DQ    P   RLSREL + EK  EVLQ  LD    TPS    L+DS +   S  
Sbjct: 1552 DHKSEKDQAGLEPLALRLSRELQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSSTS 1611

Query: 390  YVLEQQRVGLAIDMDEIEKYQEVEE 414
            ++ ++  +    DMD + +Y   EE
Sbjct: 1612 FLSDE--LEACSDMDIVSEYTHYEE 1634



 Score = 34.3 bits (77), Expect = 0.38
 Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 4/75 (5%)

Query: 483  KDQEEEEDQG---PPCPRLSRELLEVVEP-EVLQDSLDRCYSTPSSCLEQPDSCQPYGSS 538
            KD + E+DQ    P   RLSREL E  +  EVLQ  LD    TPSS     DS +   S+
Sbjct: 1551 KDHKSEKDQAGLEPLALRLSRELQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSST 1610

Query: 539  FYALEEKHVGFSLDV 553
             +  +E      +D+
Sbjct: 1611 SFLSDELEACSDMDI 1625



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 41/187 (21%), Positives = 78/187 (41%), Gaps = 34/187 (18%)

Query: 14  EMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRN 73
           E NI  +N  L    + K+Q  +  +E          L  R    K  E  +++   LR 
Sbjct: 433 EQNIQHLNHSL----SHKEQLLQEFRE---------LLQYRDNSDKTLEANEMLLEKLRQ 479

Query: 74  ERQFK--------EEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNE 125
               K        +EK +   ++ +ELRQ ++ V  ++ +L +LR+ L       +S+  
Sbjct: 480 RIHDKAVALERAIDEKFSALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQSMES 539

Query: 126 HLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKS 185
            L+A          +G ++ EQL+  C+  Q L +++  +      E  Q  + +++Q S
Sbjct: 540 LLRA----------KGLEV-EQLSTTCQNLQWLKEEMETKFSRWQKE--QESIIQQLQTS 586

Query: 186 SAPREMQ 192
              R  +
Sbjct: 587 LHDRNKE 593



 Score = 32.3 bits (72), Expect = 1.5
 Identities = 32/91 (35%), Positives = 43/91 (47%), Gaps = 6/91 (6%)

Query: 408  KYQEVEEDQ---DPSCPRLSRELLD-EKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSA 463
            K  + E+DQ   +P   RLSREL + EK  EVLQ  LD    TPS    L D  +  SS 
Sbjct: 1551 KDHKSEKDQAGLEPLALRLSRELQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSST 1610

Query: 464  VYSLEEQYLGLALAVDRIKKDQEEEEDQGPP 494
             +  +E  L     +D + +    EE +  P
Sbjct: 1611 SFLSDE--LEACSDMDIVSEYTHYEEKKASP 1639



 Score = 30.8 bits (68), Expect = 4.2
 Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 3/80 (3%)

Query: 90   EELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 149
            E+ R+ +  +    RE +Q  E LRE   +SRS   HLQ L    E  K + Q L E L 
Sbjct: 1909 EDNRRLQAQLSHVSREHSQETESLREALLSSRS---HLQELEKELEHQKVERQQLLEDLR 1965

Query: 150  EGCRLTQHLVQKLSPENDND 169
            E  +   H  ++     +ND
Sbjct: 1966 EKQQEVLHFREERLSLQEND 1985



 Score = 30.4 bits (67), Expect = 5.5
 Identities = 33/134 (24%), Positives = 64/134 (47%), Gaps = 13/134 (9%)

Query: 18  LEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFM------L 71
           LEI +KL+  + +K++Q  + K+     + A   + +QK+  ++  ++L K +      L
Sbjct: 353 LEI-QKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEEL 411

Query: 72  RNE----RQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKL--REGRDASRSLNE 125
           +N+    R ++ EK  E   Q + ++     +  +E+ L + RE L  R+  D +   NE
Sbjct: 412 QNKSQQLRAWEAEKYNEIRTQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANE 471

Query: 126 HLQALLTPDEPDKS 139
            L   L     DK+
Sbjct: 472 MLLEKLRQRIHDKA 485


>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 828

 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 111/582 (19%), Positives = 221/582 (37%), Gaps = 68/582 (11%)

Query: 8   LSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLI 67
           +++E+ +    E+ EKLR   +EK +   N+KE                K K E  K L+
Sbjct: 180 ITNEELKKKNAELQEKLRLAESEKSEIQLNVKEL---------------KRKLERAKFLL 224

Query: 68  KFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHL 127
             +  N  Q       E  +Q EELR+ +  +  QE ++ +  E+LRE     R   E +
Sbjct: 225 PQVQTNTLQ------EEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKM 278

Query: 128 QALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSA 187
           +         + + ++ +++L E  +L +   Q    E    + E+   E  EK+ +   
Sbjct: 279 RRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEE 338

Query: 188 ---PREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSS 244
               +E Q  E+++   D  E             D     K+ ++  E++K+        
Sbjct: 339 RLWEQEKQMREQEQKMRDQEERM--------WEQDERLREKEERMR-EQEKMWEQEEKMQ 389

Query: 245 SHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEML 304
                 +    + E E    E+EEK      N+ E EE+E  Q+   E    L    +M 
Sbjct: 390 EEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQ 449

Query: 305 ASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDS 364
              +        + +Q+     +  +  W Q K  +QE        ++ D+++   + D 
Sbjct: 450 EQEEKIWEQEEKIRDQEEMWGQE--KKMWRQEKMREQEDQMWEQEEKMRDQEQK--MWDQ 505

Query: 365 LDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAID------MDEIEKYQEVEEDQDP 418
            +R +       E  +  +  +  +   E+ R             D+ EK +E E  ++ 
Sbjct: 506 EERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMRER 565

Query: 419 SCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAV 478
                  E +  ++ E +Q+  ++         E  +  Q     ++  EE         
Sbjct: 566 EKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE--------- 616

Query: 479 DRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSS 538
              K  ++EEED+        +E +   + E +Q+  ++ +       EQ +  +     
Sbjct: 617 ---KMWEQEEEDK-----MQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQ--- 665

Query: 539 FYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKE 580
               EEK  G    + E E+K +G++ +  R ++++ RG++E
Sbjct: 666 ----EEKMQGQEEKMREQEEKMQGQEEK-MREQEEKMRGQEE 702


>gi|7657138 golgi integral membrane protein 4 [Homo sapiens]
          Length = 696

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 63/279 (22%), Positives = 121/279 (43%), Gaps = 32/279 (11%)

Query: 32  KQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLA-EQLKQAE 90
           ++Q R  KE+    + A  L    +   Y   K +IKF    E Q ++++LA +Q+++A+
Sbjct: 366 EEQDREWKEQHEQREAANLLEGHARAEVYPSAKPMIKFQSPYEEQLEQQRLAVQQVEEAQ 425

Query: 91  ELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAE 150
           +LR+++  +H Q  +   LR++ ++ +  +R +    QA L   E  + Q Q+   Q A 
Sbjct: 426 QLREHQEALHQQRLQGHLLRQQEQQQQQVAREMALQRQAEL---EEGRPQHQEQLRQQAH 482

Query: 151 GCRLTQHLVQKLSP----------ENDNDDDEDVQVEVAEKVQ-KSSAPREMQKAEEKE- 198
              +   +VQ              E DN   ++ + +   + + +   PRE     E + 
Sbjct: 483 YDAMDNDIVQGAEDQGIQGEEGAYERDNQHQDEAEGDPGNRHEPREQGPREADPESEADR 542

Query: 199 --------------VPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSS 244
                           ED  EE A      + P D N+  K++    E  +V+  L+ + 
Sbjct: 543 AAVEDINPADDPNNQGEDEFEE-AEQVREENLP-DENEEQKQSNQKQENTEVEEHLVMAG 600

Query: 245 SHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEE 283
           +  + ED V    + E+++E +E+      R L+ + EE
Sbjct: 601 NPDQQEDNVDEQYQEEAEEEVQEDLTEEKKRELEHNAEE 639



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 34/147 (23%), Positives = 60/147 (40%), Gaps = 26/147 (17%)

Query: 136 PDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDD-DEDVQVEVAEKVQKSSAPREMQKA 194
           PD+++ Q    Q  E   + +HLV   +P+   D+ DE  Q E  E+VQ           
Sbjct: 574 PDENEEQKQSNQKQENTEVEEHLVMAGNPDQQEDNVDEQYQEEAEEEVQ----------- 622

Query: 195 EEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVEWEDAVH 254
             +++ E+   E       ++G  D N   K      +E + D+   G   H        
Sbjct: 623 --EDLTEEKKRELEHNAEETYGENDENTDDKNNDGEEQEVRDDNRPKGREEHY------- 673

Query: 255 IIPENESDDEEEEEKGPVSPRNLQESE 281
                E ++EEEE+   V+ ++ + +E
Sbjct: 674 -----EEEEEEEEDGAAVAEKSHRRAE 695



 Score = 36.2 bits (82), Expect = 0.10
 Identities = 70/315 (22%), Positives = 117/315 (37%), Gaps = 33/315 (10%)

Query: 72  RNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLRE-------KLREGRDASRSLN 124
           R     K++ L  Q ++ +EL + K  V+    E  QLR+       +L++ +   ++L 
Sbjct: 148 RTFNDHKQKYLQLQQEKEQELSKLKETVYNLREENRQLRKAHQDIHTQLQDVKQQHKNLL 207

Query: 125 EHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQK 184
              + L+   E  KS     Q Q+AE  +L   L +  S    +  ++    +VA   Q 
Sbjct: 208 SEHEQLVVTLEDHKSALAAAQTQVAEYKQLKDTLNRIPSLRKPDPAEQQNVTQVAHSPQG 267

Query: 185 SSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSS 244
            +  RE    E +EV  ++         N        +  K    T +E +  +      
Sbjct: 268 YNTAREKPTREVQEVSRNN-----DVWQNHEAVPGRAEDTKLYAPTHKEAEFQAPPEPIQ 322

Query: 245 SHVEW-EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQE---SWD--------- 291
             VE  E   H + E      EEEE   V      E E +  P+E    W          
Sbjct: 323 QEVERREPEEHQVEEEHRKALEEEEMEQVGQAEHLEEEHDPSPEEQDREWKEQHEQREAA 382

Query: 292 ---EGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEAT-GPR 347
              EG++   + P      +  S     LE+Q++     + +    Q  +E QEA    R
Sbjct: 383 NLLEGHARAEVYPSAKPMIKFQSPYEEQLEQQRLA----VQQVEEAQQLREHQEALHQQR 438

Query: 348 LSRELLDEKEPEVLQ 362
           L   LL ++E +  Q
Sbjct: 439 LQGHLLRQQEQQQQQ 453



 Score = 34.7 bits (78), Expect = 0.29
 Identities = 87/442 (19%), Positives = 171/442 (38%), Gaps = 73/442 (16%)

Query: 17  ILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAG---FLANRQKKYKYEECKDLIKFMLRN 73
           + E   +L   L +++ + +  KE   + +L         RQ         ++   ML++
Sbjct: 64  VYEHRSRLEKSLQKERLEHKKAKEDFLVYKLEAQETLNKGRQDSNSRYSALNVQHQMLKS 123

Query: 74  ERQFKEEKLA----EQLKQAEEL--------RQYKVLVHAQERELTQLREKLREGRDASR 121
           + +  +++ +    E  KQ E+         ++Y  L   +E+EL++L+E +   R+ +R
Sbjct: 124 QHEELKKQHSDLEEEHRKQGEDFSRTFNDHKQKYLQLQQEKEQELSKLKETVYNLREENR 183

Query: 122 SLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAEK 181
            L +  Q + T  +  K Q ++L         L++H    ++ E+        Q +VAE 
Sbjct: 184 QLRKAHQDIHTQLQDVKQQHKNL---------LSEHEQLVVTLEDHKSALAAAQTQVAEY 234

Query: 182 VQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLI 241
            Q       +    +     D  E+  +T   +H P   N   +K   T E  +V     
Sbjct: 235 KQLKDTLNRIPSLRK----PDPAEQQNVT-QVAHSPQGYNTAREKP--TREVQEV----- 282

Query: 242 GSSSHVEWEDAVHIIPENESDDE-----EEEEKGPVSPRNLQESEEEEVPQESWDEGYST 296
            S ++  W++    +P    D +      +E +    P  +Q+  E   P+E   E    
Sbjct: 283 -SRNNDVWQNH-EAVPGRAEDTKLYAPTHKEAEFQAPPEPIQQEVERREPEEHQVE---- 336

Query: 297 LSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEK 356
                      + +       E +QV  A  +        +++D+E       +E  +++
Sbjct: 337 -----------EEHRKALEEEEMEQVGQAEHLEEEHDPSPEEQDRE------WKEQHEQR 379

Query: 357 EPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQ 416
           E   L +   R    PS    +     PY      LEQQR+     + ++E+ Q++ E Q
Sbjct: 380 EAANLLEGHARAEVYPS-AKPMIKFQSPYEEQ---LEQQRLA----VQQVEEAQQLREHQ 431

Query: 417 DP-SCPRLSRELLDEKEPEVLQ 437
           +     RL   LL ++E +  Q
Sbjct: 432 EALHQQRLQGHLLRQQEQQQQQ 453


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
            sapiens]
          Length = 1972

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 95/474 (20%), Positives = 194/474 (40%), Gaps = 51/474 (10%)

Query: 25   RPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAE 84
            R   A+++QQ   +K        A +L  + + +++      +K +L+  RQ +E +  E
Sbjct: 803  RKAFAKRQQQLTAMK--VIQRNCAAYL--KLRNWQWWRLFTKVKPLLQVTRQEEEMQAKE 858

Query: 85   QLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDL 144
               Q  + RQ K      E EL +L +K  +  +    L E LQA    +    ++ +++
Sbjct: 859  DELQKTKERQQKA-----ENELKELEQKHSQLTEEKNLLQEQLQA----ETELYAEAEEM 909

Query: 145  QEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSL 204
            + +LA   +  + ++ ++    + ++D   Q++   K          ++ EE+E     L
Sbjct: 910  RVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL 969

Query: 205  EECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESD-- 262
            +   +T               + KI   ED++   L+    + +      ++ E  SD  
Sbjct: 970  QLEKVTA--------------EAKIKKLEDEI---LVMDDQNNKLSKERKLLEERISDLT 1012

Query: 263  ----DEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLE 318
                +EEE+ K     +N  ES   E+      E  S   +  ++    +  +S FH   
Sbjct: 1013 TNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQEL-EKLKRKLEGDASDFH--- 1068

Query: 319  EQQVCMAVDIGRHRWDQVKKEDQ-EATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLE 377
            EQ   +   I   +    KKE++ +A   RL  E+  +       ++L +         +
Sbjct: 1069 EQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQK------NNALKKIRELEGHISD 1122

Query: 378  LTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQ 437
            L +     R+A    E+Q+  L  +++ ++   E+E+  D +  +       E+E  VL+
Sbjct: 1123 LQEDLDSERAARNKAEKQKRDLGEELEALK--TELEDTLDSTATQQELRAKREQEVTVLK 1180

Query: 438  DSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEEDQ 491
             +LD    T S   ++ ++ Q ++ AV  L EQ      A   + K+++  E +
Sbjct: 1181 KALDE--ETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKE 1232



 Score = 33.9 bits (76), Expect = 0.50
 Identities = 31/125 (24%), Positives = 58/125 (46%), Gaps = 8/125 (6%)

Query: 10   SEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKF 69
            +E A   +   N++LR +L E +   ++ K K  +  L   +A  +++ + E  +   K 
Sbjct: 1783 NESARQQLERQNKELRSKLHEMEGAVKS-KFKSTIAALEAKIAQLEEQVEQEARE---KQ 1838

Query: 70   MLRNERQFKEEKLAEQLKQAEELR----QYKVLVHAQERELTQLREKLREGRDASRSLNE 125
                  + K++KL E L Q E+ R    QYK         + QL+ +L E  + S+ +N 
Sbjct: 1839 AATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINA 1898

Query: 126  HLQAL 130
            + + L
Sbjct: 1899 NRRKL 1903



 Score = 30.4 bits (67), Expect = 5.5
 Identities = 30/117 (25%), Positives = 52/117 (44%), Gaps = 11/117 (9%)

Query: 14   EMNILEINEKLRPQLAEK-------KQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDL 66
            E  I ++ E++  +  EK       KQ+ + LKE     +    +A + K+ + E+    
Sbjct: 1820 EAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKE-QAEKGNAR 1878

Query: 67   IKFMLRNERQFKEEKL---AEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120
            +K + R   + +EE     A + K   EL +      A  RE+  L+ KLR G + S
Sbjct: 1879 VKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETS 1935


>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
            sapiens]
          Length = 1979

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 95/474 (20%), Positives = 194/474 (40%), Gaps = 51/474 (10%)

Query: 25   RPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAE 84
            R   A+++QQ   +K        A +L  + + +++      +K +L+  RQ +E +  E
Sbjct: 810  RKAFAKRQQQLTAMK--VIQRNCAAYL--KLRNWQWWRLFTKVKPLLQVTRQEEEMQAKE 865

Query: 85   QLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDL 144
               Q  + RQ K      E EL +L +K  +  +    L E LQA    +    ++ +++
Sbjct: 866  DELQKTKERQQKA-----ENELKELEQKHSQLTEEKNLLQEQLQA----ETELYAEAEEM 916

Query: 145  QEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSL 204
            + +LA   +  + ++ ++    + ++D   Q++   K          ++ EE+E     L
Sbjct: 917  RVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL 976

Query: 205  EECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESD-- 262
            +   +T               + KI   ED++   L+    + +      ++ E  SD  
Sbjct: 977  QLEKVTA--------------EAKIKKLEDEI---LVMDDQNNKLSKERKLLEERISDLT 1019

Query: 263  ----DEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLE 318
                +EEE+ K     +N  ES   E+      E  S   +  ++    +  +S FH   
Sbjct: 1020 TNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQEL-EKLKRKLEGDASDFH--- 1075

Query: 319  EQQVCMAVDIGRHRWDQVKKEDQ-EATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLE 377
            EQ   +   I   +    KKE++ +A   RL  E+  +       ++L +         +
Sbjct: 1076 EQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQK------NNALKKIRELEGHISD 1129

Query: 378  LTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQ 437
            L +     R+A    E+Q+  L  +++ ++   E+E+  D +  +       E+E  VL+
Sbjct: 1130 LQEDLDSERAARNKAEKQKRDLGEELEALK--TELEDTLDSTATQQELRAKREQEVTVLK 1187

Query: 438  DSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEEDQ 491
             +LD    T S   ++ ++ Q ++ AV  L EQ      A   + K+++  E +
Sbjct: 1188 KALDE--ETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKE 1239



 Score = 33.9 bits (76), Expect = 0.50
 Identities = 31/125 (24%), Positives = 58/125 (46%), Gaps = 8/125 (6%)

Query: 10   SEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKF 69
            +E A   +   N++LR +L E +   ++ K K  +  L   +A  +++ + E  +   K 
Sbjct: 1790 NESARQQLERQNKELRSKLHEMEGAVKS-KFKSTIAALEAKIAQLEEQVEQEARE---KQ 1845

Query: 70   MLRNERQFKEEKLAEQLKQAEELR----QYKVLVHAQERELTQLREKLREGRDASRSLNE 125
                  + K++KL E L Q E+ R    QYK         + QL+ +L E  + S+ +N 
Sbjct: 1846 AATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINA 1905

Query: 126  HLQAL 130
            + + L
Sbjct: 1906 NRRKL 1910



 Score = 30.4 bits (67), Expect = 5.5
 Identities = 30/117 (25%), Positives = 52/117 (44%), Gaps = 11/117 (9%)

Query: 14   EMNILEINEKLRPQLAEK-------KQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDL 66
            E  I ++ E++  +  EK       KQ+ + LKE     +    +A + K+ + E+    
Sbjct: 1827 EAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKE-QAEKGNAR 1885

Query: 67   IKFMLRNERQFKEEKL---AEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120
            +K + R   + +EE     A + K   EL +      A  RE+  L+ KLR G + S
Sbjct: 1886 VKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETS 1942


>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
            sapiens]
          Length = 1945

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 95/474 (20%), Positives = 194/474 (40%), Gaps = 51/474 (10%)

Query: 25   RPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAE 84
            R   A+++QQ   +K        A +L  + + +++      +K +L+  RQ +E +  E
Sbjct: 810  RKAFAKRQQQLTAMK--VIQRNCAAYL--KLRNWQWWRLFTKVKPLLQVTRQEEEMQAKE 865

Query: 85   QLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDL 144
               Q  + RQ K      E EL +L +K  +  +    L E LQA    +    ++ +++
Sbjct: 866  DELQKTKERQQKA-----ENELKELEQKHSQLTEEKNLLQEQLQA----ETELYAEAEEM 916

Query: 145  QEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSL 204
            + +LA   +  + ++ ++    + ++D   Q++   K          ++ EE+E     L
Sbjct: 917  RVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL 976

Query: 205  EECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESD-- 262
            +   +T               + KI   ED++   L+    + +      ++ E  SD  
Sbjct: 977  QLEKVTA--------------EAKIKKLEDEI---LVMDDQNNKLSKERKLLEERISDLT 1019

Query: 263  ----DEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLE 318
                +EEE+ K     +N  ES   E+      E  S   +  ++    +  +S FH   
Sbjct: 1020 TNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQEL-EKLKRKLEGDASDFH--- 1075

Query: 319  EQQVCMAVDIGRHRWDQVKKEDQ-EATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLE 377
            EQ   +   I   +    KKE++ +A   RL  E+  +       ++L +         +
Sbjct: 1076 EQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQK------NNALKKIRELEGHISD 1129

Query: 378  LTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQ 437
            L +     R+A    E+Q+  L  +++ ++   E+E+  D +  +       E+E  VL+
Sbjct: 1130 LQEDLDSERAARNKAEKQKRDLGEELEALK--TELEDTLDSTATQQELRAKREQEVTVLK 1187

Query: 438  DSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEEDQ 491
             +LD    T S   ++ ++ Q ++ AV  L EQ      A   + K+++  E +
Sbjct: 1188 KALDE--ETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKE 1239



 Score = 33.9 bits (76), Expect = 0.50
 Identities = 31/125 (24%), Positives = 58/125 (46%), Gaps = 8/125 (6%)

Query: 10   SEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKF 69
            +E A   +   N++LR +L E +   ++ K K  +  L   +A  +++ + E  +   K 
Sbjct: 1790 NESARQQLERQNKELRSKLHEMEGAVKS-KFKSTIAALEAKIAQLEEQVEQEARE---KQ 1845

Query: 70   MLRNERQFKEEKLAEQLKQAEELR----QYKVLVHAQERELTQLREKLREGRDASRSLNE 125
                  + K++KL E L Q E+ R    QYK         + QL+ +L E  + S+ +N 
Sbjct: 1846 AATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINA 1905

Query: 126  HLQAL 130
            + + L
Sbjct: 1906 NRRKL 1910


>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
            sapiens]
          Length = 1938

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 95/474 (20%), Positives = 194/474 (40%), Gaps = 51/474 (10%)

Query: 25   RPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAE 84
            R   A+++QQ   +K        A +L  + + +++      +K +L+  RQ +E +  E
Sbjct: 803  RKAFAKRQQQLTAMK--VIQRNCAAYL--KLRNWQWWRLFTKVKPLLQVTRQEEEMQAKE 858

Query: 85   QLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDL 144
               Q  + RQ K      E EL +L +K  +  +    L E LQA    +    ++ +++
Sbjct: 859  DELQKTKERQQKA-----ENELKELEQKHSQLTEEKNLLQEQLQA----ETELYAEAEEM 909

Query: 145  QEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSL 204
            + +LA   +  + ++ ++    + ++D   Q++   K          ++ EE+E     L
Sbjct: 910  RVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL 969

Query: 205  EECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESD-- 262
            +   +T               + KI   ED++   L+    + +      ++ E  SD  
Sbjct: 970  QLEKVTA--------------EAKIKKLEDEI---LVMDDQNNKLSKERKLLEERISDLT 1012

Query: 263  ----DEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLE 318
                +EEE+ K     +N  ES   E+      E  S   +  ++    +  +S FH   
Sbjct: 1013 TNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQEL-EKLKRKLEGDASDFH--- 1068

Query: 319  EQQVCMAVDIGRHRWDQVKKEDQ-EATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLE 377
            EQ   +   I   +    KKE++ +A   RL  E+  +       ++L +         +
Sbjct: 1069 EQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQK------NNALKKIRELEGHISD 1122

Query: 378  LTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQ 437
            L +     R+A    E+Q+  L  +++ ++   E+E+  D +  +       E+E  VL+
Sbjct: 1123 LQEDLDSERAARNKAEKQKRDLGEELEALK--TELEDTLDSTATQQELRAKREQEVTVLK 1180

Query: 438  DSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEEDQ 491
             +LD    T S   ++ ++ Q ++ AV  L EQ      A   + K+++  E +
Sbjct: 1181 KALDE--ETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKE 1232



 Score = 33.9 bits (76), Expect = 0.50
 Identities = 31/125 (24%), Positives = 58/125 (46%), Gaps = 8/125 (6%)

Query: 10   SEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKF 69
            +E A   +   N++LR +L E +   ++ K K  +  L   +A  +++ + E  +   K 
Sbjct: 1783 NESARQQLERQNKELRSKLHEMEGAVKS-KFKSTIAALEAKIAQLEEQVEQEARE---KQ 1838

Query: 70   MLRNERQFKEEKLAEQLKQAEELR----QYKVLVHAQERELTQLREKLREGRDASRSLNE 125
                  + K++KL E L Q E+ R    QYK         + QL+ +L E  + S+ +N 
Sbjct: 1839 AATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINA 1898

Query: 126  HLQAL 130
            + + L
Sbjct: 1899 NRRKL 1903


>gi|21735548 centrosomal protein 2 [Homo sapiens]
          Length = 2442

 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 120/527 (22%), Positives = 204/527 (38%), Gaps = 82/527 (15%)

Query: 22   EKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRN-------E 74
            E L   L  + Q+    KE+    Q+      RQ K   EE  + IK  LR        +
Sbjct: 1647 EHLTQDLERRDQELMLQKERI---QVLEDQRTRQTKI-LEEDLEQIKLSLRERGRELTTQ 1702

Query: 75   RQFKEEKLAE----QLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQAL 130
            RQ  +E+  E       Q   L   K+++  +E+E+   +E + E ++    L + LQ L
Sbjct: 1703 RQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLQGL 1762

Query: 131  ----------LTPDEPD-KSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVA 179
                      L+  E +     Q LQE   +G    Q L  +L          D ++E  
Sbjct: 1763 HRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEAL 1822

Query: 180  EKVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDST 239
            ++ Q+ +  +E +  E+ +  + +LE+  +T    HG     Q HK+     EE+     
Sbjct: 1823 QQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGEL---QDHKEQARRLEEE----- 1874

Query: 240  LIGSSSHVEWEDAVHIIPENESDDEEEEEKG--PVSPRNLQESEEEEVP----QESWDEG 293
            L      V+   A+  +  +   +  E+EK    +  +  ++++E EV     Q+SW + 
Sbjct: 1875 LAVEGRRVQ---ALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQDSWLQA 1931

Query: 294  YSTLSIPPEMLASYQSYSSTFHSLEE----QQVCMAVDIGRHRWDQVKKEDQEATGPRLS 349
             + L    + L + ++ S +    EE    +   +   +G+       KE        LS
Sbjct: 1932 QAVLKERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELS 1991

Query: 350  RELLDEKEPEVLQDSLDRCYSTPSGCL--------ELTDSCQPYRSAFYVLEQQRVGLAI 401
            R L  E     LQ SLD C +              E+ D    Y+     L+Q    LA 
Sbjct: 1992 RSL--EASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQ---ALAQ 2046

Query: 402  DMDEIEKYQEVEEDQDPS-CPRLSRELLDEK--------EPEV--LQDSLDRCYST---- 446
              +E+   QE E+  + S   R+   ++ EK        E E+  L  S+     T    
Sbjct: 2047 RDEELRHQQEREQLLEKSLAQRVQENMIQEKQNLGQEREEEEIRGLHQSVRELQLTLAQK 2106

Query: 447  PSDYLELPDLGQ-------PYSSAVYSLEEQYLGLALAVDRIKKDQE 486
              + LEL +  Q       P+S     +EEQ L L     R++++ E
Sbjct: 2107 EQEILELRETQQRNNLEALPHSHKTSPMEEQSLKLDSLEPRLQRELE 2153



 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 51/193 (26%), Positives = 89/193 (46%), Gaps = 22/193 (11%)

Query: 11   EKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFM 70
            E  E   +E+  +L+ Q  E +      +E+   TQ    L   Q + + E    L++ +
Sbjct: 878  ESLEREKMELEMRLKEQQTEMEAIQAQREEE--RTQAESALCQMQLETEKERVS-LLETL 934

Query: 71   LRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELT-----QLREKLREGRDASRSLNE 125
            L+ +++     LA+  +Q E LRQ   +   +E+E T     QL+E  RE ++A+R   +
Sbjct: 935  LQTQKE-----LADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRD 989

Query: 126  HLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKS 185
             L AL            DLQ+Q+ +   L   LV +      +D    V+ EV EK++++
Sbjct: 990  DLAALQEESSSLLQDKMDLQKQVED---LKSQLVAQ------DDSQRLVEQEVQEKLRET 1040

Query: 186  SAPREMQKAEEKE 198
                 +QK  E+E
Sbjct: 1041 QEYNRIQKELERE 1053



 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 105/471 (22%), Positives = 184/471 (39%), Gaps = 90/471 (19%)

Query: 44   LTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQE 103
            L +L   +A+ Q + +  E   L +   + ER+  +        Q E L+   V   AQ 
Sbjct: 1315 LMELHETMASLQSRLRRAE---LQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQA 1371

Query: 104  RELTQLREKLREGRDASRSLNEHL-------QALLTPDEPDKSQGQDLQEQLAEGCRLTQ 156
                 L E LR  R A +  NE +       QAL    E   +QG+ LQE LA    LTQ
Sbjct: 1372 SAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLA---LLTQ 1428

Query: 157  HLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHG 216
             L ++         +E+V+  +  ++Q+    REMQKA        +LE  ++       
Sbjct: 1429 TLAER---------EEEVET-LRGQIQELEKQREMQKA--------ALELLSLDLKK--- 1467

Query: 217  PYDSNQPHKKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRN 276
                    +  ++  +++++           E E    ++       +E E+K  V    
Sbjct: 1468 --------RNQEVDLQQEQIQ----------ELEKCRSVLEHLPMAVQEREQKLTVQREQ 1509

Query: 277  LQESEEE-EVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQV---CMAVDI--GR 330
            ++E E++ E  +   +     L    +M+   +S       L++Q V   C+A+++    
Sbjct: 1510 IRELEKDRETQRNVLEHQLLELEKKDQMI---ESQRGQVQDLKKQLVTLECLALELEENH 1566

Query: 331  HRWDQVKKEDQEATGPR------LSRELLD-EKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383
            H+ +  +K  +E  G R      L+   LD E+  + LQ    + +   S    L     
Sbjct: 1567 HKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARE-- 1624

Query: 384  PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEP-EVLQDSLDR 442
                    L+++   +    ++IE+ Q  +E       R  +EL+ +KE  +VL+D   R
Sbjct: 1625 --------LQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTR 1676

Query: 443  CYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEEDQGP 493
                  + LE   L         SL E+  G  L   R    +  EE +GP
Sbjct: 1677 QTKILEEDLEQIKL---------SLRER--GRELTTQRQLMQERAEEGKGP 1716



 Score = 39.7 bits (91), Expect = 0.009
 Identities = 56/217 (25%), Positives = 96/217 (44%), Gaps = 34/217 (15%)

Query: 8    LSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQL-----AGFL------ANRQK 56
            L +EK  +++LE   + + +LA+  QQ   L++   + +L      G L      A R+ 
Sbjct: 921  LETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQREL 980

Query: 57   KYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQ-LREKLRE 115
            K    + +D +  +        ++K+  Q KQ E+L+   V     +R + Q ++EKLRE
Sbjct: 981  KEAARQHRDDLAALQEESSSLLQDKMDLQ-KQVEDLKSQLVAQDDSQRLVEQEVQEKLRE 1039

Query: 116  GRDASR--------------SLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQK 161
             ++ +R              SL E  Q LL   E D  + Q+L   L +  +  Q   ++
Sbjct: 1040 TQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQEL-SALRQDMQEAQGEQKE 1098

Query: 162  LSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKE 198
            LS +      E ++ EV EK +     +E Q  EE E
Sbjct: 1099 LSAQM-----ELLRQEVKEK-EADFLAQEAQLLEELE 1129



 Score = 35.8 bits (81), Expect = 0.13
 Identities = 39/149 (26%), Positives = 73/149 (48%), Gaps = 14/149 (9%)

Query: 11   EKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECK-DLIKF 69
            E+ E+ + +  + L+  LA   Q     +E+  +  L G +   +K+ + ++   +L+  
Sbjct: 1407 EQGELKVAQ-GKALQENLALLTQTLAEREEE--VETLRGQIQELEKQREMQKAALELLSL 1463

Query: 70   MLRNERQ---FKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLRE---GRDASRSL 123
             L+   Q    ++E++ E  K    L    + V  +E++LT  RE++RE    R+  R++
Sbjct: 1464 DLKKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNV 1523

Query: 124  NEH-LQALLTPD---EPDKSQGQDLQEQL 148
             EH L  L   D   E  + Q QDL++QL
Sbjct: 1524 LEHQLLELEKKDQMIESQRGQVQDLKKQL 1552



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 60/221 (27%), Positives = 89/221 (40%), Gaps = 58/221 (26%)

Query: 8   LSSEKAEMNI-LEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKY-------- 58
           L  EKA + + L+  E+ R  LAE+ Q   + KE   L + + F A +Q           
Sbjct: 734 LVREKAALEVRLQAVERDRQDLAEQLQGLSSAKE---LLESSLFEAQQQNSVIEVTKGQL 790

Query: 59  -----KYEECKDLI-------KFMLRNERQFKEEK---LAEQLKQAEE-----LRQYKVL 98
                   + K++I       K  L  ER   E++    A QL QAE+     L Q K  
Sbjct: 791 EVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKA- 849

Query: 99  VHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHL 158
             A E+E+ QLREK  + R      + H Q L    E  + +  +L+ +L E        
Sbjct: 850 --AHEKEVNQLREKWEKER------SWHQQELAKALESLEREKMELEMRLKE-------- 893

Query: 159 VQKLSPENDNDDDEDVQVE-VAEKVQKSSAPREMQKAEEKE 198
                      + E +Q +   E+ Q  SA  +MQ   EKE
Sbjct: 894 --------QQTEMEAIQAQREEERTQAESALCQMQLETEKE 926



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 117/577 (20%), Positives = 221/577 (38%), Gaps = 107/577 (18%)

Query: 14   EMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRN 73
            E  +LE+ EK    +  ++ Q ++LK++  L  L       ++ +   EC+  +   L  
Sbjct: 1525 EHQLLEL-EKKDQMIESQRGQVQDLKKQ--LVTLECLALELEENHHKMECQQKLIKELEG 1581

Query: 74   ERQFKEEKLAEQL----KQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 129
            +R+ +   L        ++++EL+     +H  E   T L  +L+E              
Sbjct: 1582 QRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQER------------- 1628

Query: 130  LLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR 189
                D+  KSQ    +EQ+ E  R  +HL Q L        D+++ ++  E++Q      
Sbjct: 1629 ----DQEVKSQ----REQIEELQRQKEHLTQDLERR-----DQELMLQ-KERIQ----VL 1670

Query: 190  EMQKAEEKEVPEDSLEECAITCSN------------SHGPYDSNQPHKKTKITFEEDKVD 237
            E Q+  + ++ E+ LE+  ++                    +   P K  + + E  K+ 
Sbjct: 1671 EDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKL- 1729

Query: 238  STLIGSSSHVE-WEDAVHIIPENESDDEEE-----EEKGPVSPRNLQESEEEEVPQESWD 291
              L      VE  ++ +H + E +   E++      + G  S    Q  +E  V Q+   
Sbjct: 1730 -ILRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQ 1788

Query: 292  EGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRE 351
            E      +  + L S          L+E Q  +A        + +++E Q+A G     E
Sbjct: 1789 EAREQGELKEQSLQS---------QLDEAQRALAQ--RDQELEALQQEQQQAQG---QEE 1834

Query: 352  LLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQE 411
             + EK  + LQ +L++ + T     E     Q ++     LE++   LA++   ++  +E
Sbjct: 1835 RVKEK-ADALQGALEQAHMT---LKERHGELQDHKEQARRLEEE---LAVEGRRVQALEE 1887

Query: 412  VEEDQDPSCPRLSREL--LDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEE 469
            V  D         + L  L ++  E  Q+      +    +L+        + AV    +
Sbjct: 1888 VLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQDSWLQ--------AQAVLKERD 1939

Query: 470  QYLGLALAVDRIKKDQEE---------EEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYS 520
            Q L    A  +  + QEE         +E  G     L  +   ++E   L  SL+   +
Sbjct: 1940 QELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELSRSLEASTA 1999

Query: 521  TPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIE 557
            T  + L   D+CQ +      LEE      +  GEI+
Sbjct: 2000 TLQASL---DACQAHSRQ---LEE---ALRIQEGEIQ 2027


>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 899

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 72/342 (21%), Positives = 144/342 (42%), Gaps = 46/342 (13%)

Query: 10  SEKAE--MNILEINEKL-RPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDL 66
           SEK+E  +N+ E+  KL R +    + Q   L+E+ +  +    L  ++KK + +E K  
Sbjct: 239 SEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEE--LREQEKKIRKQEEK-- 294

Query: 67  IKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREG---RDASRSL 123
              M R E + +E++  +  +Q E++ + +  +  QE+EL +  ++LRE    R+    +
Sbjct: 295 ---MWRQEERLREQE-GKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQM 350

Query: 124 NEHLQALLTPDEPDKSQGQDL---QEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180
            E  + +   +E  + Q + +   +E+L E  +  +   QK+  + +   ++D ++   E
Sbjct: 351 QEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLR--E 408

Query: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240
           K ++     +M +  EK   E  ++E                  KKT+   E+ + +  +
Sbjct: 409 KEERMREQEKMWEQVEKMREEKKMQE----------------QEKKTRDQEEKMQEEERI 452

Query: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP 300
                 +          E E    E+EEK      N+ E EE+E  Q+   E    L   
Sbjct: 453 REREKKMR---------EEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQ 503

Query: 301 PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQE 342
            +M    +        + +Q+     +  +  W Q K  +QE
Sbjct: 504 EKMQEQEEKIWEQEEKIRDQEEMWGQE--KKMWRQEKMREQE 543



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 58/294 (19%), Positives = 127/294 (43%), Gaps = 32/294 (10%)

Query: 11  EKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFM 70
           E  +  + E  EKL  Q   ++Q+ +  +++  +          +K ++ E+ ++    M
Sbjct: 487 EWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQM 546

Query: 71  LRNERQFK--EEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREG---RDASRSLNE 125
              E + +  E+K+ +Q ++ E+  Q       QE++     EK+RE    R+  + + E
Sbjct: 547 WEQEEKMRDQEQKMWDQEERMEKKTQ------EQEKKTWDQEEKMREEERMREREKKMRE 600

Query: 126 HLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKV-QK 184
             + +   +E  + Q + +QEQ  +     + + ++   E    + E+   E  EK+ ++
Sbjct: 601 EEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQ---EEKMWEQEEKMWEQEEKMWEQ 657

Query: 185 SSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKT----KITFEEDKVDSTL 240
              P + +K  E E     ++E           ++  +  KKT    K T++++K+    
Sbjct: 658 QRLPEQKEKLWEHE----KMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEE 713

Query: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEE--EVPQESWDE 292
                  +  +   ++ E E   +E+EEK       +QE EEE  E  ++ W++
Sbjct: 714 SMREREKKMREEEEMMREQEEKMQEQEEK-------MQEQEEEMWEQEEKMWEQ 760


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.130    0.370 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,319,210
Number of Sequences: 37866
Number of extensions: 1561738
Number of successful extensions: 13443
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 114
Number of HSP's successfully gapped in prelim test: 774
Number of HSP's that attempted gapping in prelim test: 8705
Number of HSP's gapped (non-prelim): 3148
length of query: 670
length of database: 18,247,518
effective HSP length: 109
effective length of query: 561
effective length of database: 14,120,124
effective search space: 7921389564
effective search space used: 7921389564
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.