Guide to the Human Genome
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Name: SMURF2 Sequence: fasta or formatted (748aa) NCBI GI: 12232397
Description:

SMAD specific E3 ubiquitin protein ligase 2

Referenced in:

Ubiquitin and Related Protein Modifications
WW Domain

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             3.5         26           2
 C cysteine            2.3         17           1
 D aspartate           6.1         46           2
 E glutamate           6.0         45           2
 F phenylalanine       4.0         30           2
 G glycine             6.8         51           2
 H histidine           3.5         26           1
 I isoleucine          4.8         36           2
 K lysine              5.3         40           2
 L leucine            10.2         76           2
 M methionine          1.2          9           1
 N asparagine          5.3         40           2
 P proline             5.3         40           2
 Q glutamine           5.6         42           5
 R arginine            7.4         55           2
 S serine              5.1         38           2
 T threonine           5.9         44           2
 V valine              6.4         48           3
 W tryptophan          1.7         13           1
 Y tyrosine            3.5         26           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   SMAD specific E3 ubiquitin protein ligase 2 
SMURF1                0.739   Smad ubiquitination regulatory factor 1 isoform 2 [H...
SMURF1                0.730   Smad ubiquitination regulatory factor 1 isoform 1 [H...
NEDD4L                0.315   neural precursor cell expressed, developmentally do...
NEDD4L                0.315   neural precursor cell expressed, developmentally dow...
NEDD4L                0.315   neural precursor cell expressed, developmentally do...
NEDD4L                0.315   neural precursor cell expressed, developmentally do...
NEDD4L                0.315   neural precursor cell expressed, developmentally do...
NEDD4L                0.315   neural precursor cell expressed, developmentally do...
NEDD4L                0.315   neural precursor cell expressed, developmentally do...
NEDD4L                0.315   neural precursor cell expressed, developmentally do...
NEDD4L                0.315   neural precursor cell expressed, developmentally do...
WWP2                  0.304   WW domain containing E3 ubiquitin protein ligase 2 i...
ITCH                  0.302   itchy homolog E3 ubiquitin protein ligase 
NEDD4                 0.300   neural precursor cell expressed, developmentally do...
NEDD4                 0.300   neural precursor cell expressed, developmentally do...
WWP1                  0.299   WW domain containing E3 ubiquitin protein ligase 1 [...
WWP2                  0.265   WW domain containing E3 ubiquitin protein ligase 2 i...
HECW2                 0.220   HECT, C2 and WW domain containing E3 ubiquitin prote...
HECW1                 0.218   NEDD4-like ubiquitin-protein ligase 1 
HUWE1                 0.200   HECT, UBA and WWE domain containing 1 
HACE1                 0.157   HECT domain and ankyrin repeat containing, E3 ubiqu...
HECTD2                0.110   HECT domain containing 2 isoform a 
UBE3A                 0.109   ubiquitin protein ligase E3A isoform 3 
UBE3A                 0.109   ubiquitin protein ligase E3A isoform 1 
UBE3A                 0.109   ubiquitin protein ligase E3A isoform 2 
KIAA0317              0.103   hypothetical protein LOC9870 
HERC4                 0.098   hect domain and RLD 4 isoform b 
HERC4                 0.098   hect domain and RLD 4 isoform a 
UBE3C                 0.094   ubiquitin protein ligase E3C 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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